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Sample records for advanced ccd imaging

  1. Advanced CCD camera developments

    SciTech Connect

    Condor, A.

    1994-11-15

    Two charge coupled device (CCD) camera systems are introduced and discussed, describing briefly the hardware involved, and the data obtained in their various applications. The Advanced Development Group Defense Sciences Engineering Division has been actively designing, manufacturing, fielding state-of-the-art CCD camera systems for over a decade. These systems were originally developed for the nuclear test program to record data from underground nuclear tests. Today, new and interesting application for these systems have surfaced and development is continuing in the area of advanced CCD camera systems, with the new CCD camera that will allow experimenters to replace film for x-ray imaging at the JANUS, USP, and NOVA laser facilities.

  2. Development of a CCD array as an imaging detector for advanced X-ray astrophysics facilities

    NASA Technical Reports Server (NTRS)

    Schwartz, D. A.

    1981-01-01

    The development of a charge coupled device (CCD) X-ray imager for a large aperture, high angular resolution X-ray telescope is discussed. Existing CCDs were surveyed and three candidate concepts were identified. An electronic camera control and computer interface, including software to drive a Fairchild 211 CCD, is described. In addition a vacuum mounting and cooling system is discussed. Performance data for the various components are given.

  3. Advanced CCD imager technology for use from 1 to 10,000 A

    NASA Technical Reports Server (NTRS)

    Twichell, J. C.; Burke, B. E.; Reich, R. K.; Mcgonagle, W. H.; Huang, C. M.

    1990-01-01

    A low-noise, high-sensitivity charge-coupled-device (CCD) technology for imaging applications extending from the soft X-ray (1 A) to the near-infrared (10,000 A) regimes was developed together with a fabrication technology for making back-illuminated versions of these devices with quantum efficiencies as high as 90 percent from 5000 to 7000 A. The efforts have focused on two devices, a 64 x 64 pixel back-illuminated imager with two output ports that operates at 2000 frames per second with 23 electrons read noise, and a larger device, with 420 x 420 pixel format, designed for lower frame rates with noise as low as 1.5 electrons and used at visible, UV, and X-ray wavelengths. Applications to plasma diagnostics include Thomson scattering and high-frame-rate imaging in the visible, as well as X-ray imaging and bolometry.

  4. Preventing Blooming In CCD Images

    NASA Technical Reports Server (NTRS)

    Janesick, James

    1992-01-01

    Clocking scheme for charge-coupled-device (CCD) imaging photodetector prevents smearing of bright spots and eliminates residual images. Also imposes charge-collecting electric field of optimum-full-well configuration, minimizes nonuniformities among picture elements, and keeps dark current low. Works under almost any lighting conditions.

  5. CCD imager with photodetector bias introduced via the CCD register

    NASA Technical Reports Server (NTRS)

    Kosonocky, Walter F. (Inventor)

    1986-01-01

    An infrared charge-coupled-device (IR-CCD) imager uses an array of Schottky-barrier diodes (SBD's) as photosensing elements and uses a charge-coupled-device (CCD) for arranging charge samples supplied in parallel from the array of SBD's into a succession of serially supplied output signal samples. Its sensitivity to infrared (IR) is improved by placing bias charges on the Schottky barrier diodes. Bias charges are transported to the Schottky barrier diodes by a CCD also used for charge sample read-out.

  6. High Precision CCD Imaging Polarimetry

    NASA Astrophysics Data System (ADS)

    Magalhaes, A. M.; Rodrigues, C. V.; Margoniner, V. E.; Pereyra, A.; Heathcote, S.; Coyne, G. V.

    1994-12-01

    We describe a recent modification to the direct CCD Cameras at CTIO and LNA (Brazil) observatories in order to allow for high precision optical polarimetry. We make use of a rotating achromatic half-wave plate as a retarder and a Savart plate as analyser. Cancellation of sky polarization and independence of the CCD flat field correction are among the advantages of the arrangement. We show preliminary data that indicate the high polarimetric precision achievable with the method for non-extended sources. We give a brief description of the on-going observational programs employing the technique. Polarimetry of extended objects can be performed by using a Polaroid sheet in place of the Savart plate. Use of the Savart plate with such fields can also be valuable in the reduction, and analysis, of the extended source images as it provides polarization data on the non-extended objects in the field.

  7. Measuring Tracking Accuracy of CCD Imagers

    NASA Technical Reports Server (NTRS)

    Stanton, R. H.; Dennison, E. W.

    1985-01-01

    Tracking accuracy and resolution of charge-coupled device (CCD) imaging arrays measured by instrument originally developed for measuring performance of star-tracking telescope. Operates by projecting one or more artifical star images on surface of CCD array, moving stars in controlled patterns, and comparing star locations computed from CCD outputs with those calculated from step coordinates of micropositioner.

  8. Large area CCD image sensors for space astronomy

    NASA Technical Reports Server (NTRS)

    Schwarzschild, M.

    1979-01-01

    The Defense Advanced Research Projects Agency (DARPA) has a substantial program to develop a 2200 x 2200 pixel CCD (Charge Coupled Device) mosaic array made up of 400 individual CCD's, 110 x 110 pixels square. This type of image sensor appeared to have application in space and ground-based astronomy. Under this grant a CCD television camera system was built which was capable of operating an array of 4 CCD's to explore the suitability of the CCD's to explore the suitability of the CCD for astronomical applications. Two individual packaged CCD's were received and evaluated. Evaluation of the basic characteristics of the best individual chips was encouraging, but the manufacturer found that their yield in manufacturing this design is two low to supply sufficient CDD's for the DARPA mosaic array. The potential utility of large mosaic arrays in astronomy is still substantial and continued monitoring of the manufacturers progress in the coming year is recommended.

  9. This is a CCD image

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This is a CCD image taken 19 July UT (18 July CDT) at 02:23 UT (9:23pm CDT) with the 0.8m telescope of The University of Texas McDonald Observatory. An 764nm filter was used. This filter shows the cloud tops of Jupiter. North is at the top and west is to the right. In the southern hemisphere three white ovals which are not associated with the comet are visible across the central meridian. To the south and west of these white ovals the impact location of comet fragment C is visible as a subtle dark patch. Barely visible near the north polar region is the shadow of the Jovian moon Ganymede. This image was taken by Dr. Wayne Pryor (University of Colorado), Dr. Chan Na (Southwest Research Institute) and Dr. Anita Cochran (University of Texas).

  10. CCD Imaging of KIC 8462852

    NASA Astrophysics Data System (ADS)

    Lahey, Adam

    2016-06-01

    A particularly interesting star, KIC 8562852, recently became famous for its enigmatic dips in brightness. The interpretation broadcast by many popular media outlets was that the dips were caused by a megastructure built around the star by an intelligent civilization. The best scientific hypothesis relies on a natural phenomenon: the break-up of a comet orbiting the star. To further address this problem, we have measured the star for four months using BGSU’s 0.5m telescope and digital CCD camera, and we present the star’s brightness as a function of time. Using three very clear nights, we refined the brightness of four comparison stars which can be used by the local astronomical community to monitor the star’s brightness. These newly refined magnitudes should reduce the uncertainties in our brightness measurements; this error analysis is essential in determining the significance of any brightness deviations. An observed dip in brightness would confirm the comet hypothesis by establishing a cyclical pattern, or may serve as a basis for new understanding of variable stars. An additional element to the project involves creating CCD calibration images and a well-documented procedure for future use.

  11. CCD Detects Two Images In Quick Succession

    NASA Technical Reports Server (NTRS)

    Janesick, James R.; Collins, Andy

    1996-01-01

    Prototype special-purpose charge-coupled device (CCD) designed to detect two 1,024 x 1,024-pixel images in rapid succession. Readout performed slowly to minimize noise. CCD operated in synchronism with pulsed laser, stroboscope, or other pulsed source of light to form pairs of images of rapidly moving objects.

  12. A multi-frame, megahertz CCD imager

    SciTech Connect

    Mendez, Jacob A; Balzer, Stephen J; Watson, Scott A

    2008-01-01

    A high-efficiency, high-speed imager has been fabricated capable of framing rates of 2 MHz. This device utilizes a 512 x 512 pixel charge coupled device (CCD) with a 25cmZ active area, and incorporates an electronic shutter technology designed for back-illuminated CCD's, making this the largest and fastest back-illuminated CCD in the world. Characterizing an imager capable of this frame rate presents unique challenges. High speed LED drivers and intense radioactive sources are needed to perform basic measurements. We investigate properties normally associated with single-frame CCD's such as read noise, gain, full-well capacity, detective quantum efficiency (DQE), sensitivity, and linearity. In addition, we investigate several properties associated with the imager's multi-frame operation such as transient frame response and frame-to-frame isolation while contrasting our measurement techniques and results with more conventional devices.

  13. A multi-frame, megahertz CCd imager

    SciTech Connect

    Mendez, Jacob; Balzer, Stephen; Watson, Scott; Reich, Robert

    2010-01-01

    To record high-speed, explosively driven, events, a high efficiency, high speed, imager has been fabricated which is capable of framing rates of 2 MHz. This device utilizes a 512 x 512 pixel charge coupled device (CCD) with a 25cm{sup 2} active area, and incorporates an electronic shutter technology designed for back-illuminated CCD's, making this the largest and fastest back-illuminated CCD in the world. Characterizing an imager capable of this frame rate presents unique challenges. High speed LED drivers and intense radioactive sources are needed to perform the most basic measurements. We investigate properties normally associated with single-frame CCD's such as read noise, full-well capacity, sensitivity, signal to noise ratio, linearity and dynamic range. In addition, we investigate several properties associated with the imager's multi-frame operation such as transient frame response and frame-to-frame isolation while contrasting our measurement techniques and results with more conventional devices.

  14. Automatic CCD Imaging Systems for Time-series CCD Photometry

    NASA Astrophysics Data System (ADS)

    Caton, D. B.; Pollock, J. T.; Davis, S. A.

    2004-12-01

    CCDs allow precision photometry to be done with small telescopes and at sites with less than ideal seeing conditions. The addition of an automatic observing mode makes it easy to do time-series CCD photometry of variable stars and AGN/QSOs. At Appalachian State University's Dark Sky Observatory (DSO), we have implemented automatic imaging systems for image acquisition, scripted filter changing, data storage and quick-look online photometry two different telescopes, the 32-inch and 18-inch telescopes. The camera at the 18-inch allows a simple system where the data acquisition PC controls a DFM Engineering filter wheel and Photometrics/Roper camera. The 32-inch system is the more complex, with three computers communicating in order to make good use of its camera's 30-second CCD-read time for filter change. Both telescopes use macros written in the PMIS software (GKR Computer Consulting). Both systems allow automatic data capture with only tended care provided by the observer. Indeed, one observer can easily run both telescopes simultaneously. The efficiency and reliability of these systems also reduces observer errors. The only unresolved problem is an occasional but rare camera-read error (the PC is apparently interrupted). We also sometimes experience a crash of the PMIS software, probably due to its 16-bit code now running in the Windows 2000 32-bit environment. We gratefully acknowledge the support of the National Science Foundation through grants number AST-0089248 and AST-9119750, the Dunham Fund for Astrophysical Research, and the ASU Research Council.

  15. CCD architecture for spacecraft SAR image processing

    NASA Technical Reports Server (NTRS)

    Arens, W. E.

    1977-01-01

    A real-time synthetic aperture radar (SAR) image processing architecture amenable to future on-board spacecraft applications is currently under development. Using state-of-the-art charge-coupled device (CCD) technology, low cost and power are inherent features. Other characteristics include the ability to reprogram correlation reference functions, correct for range migration, and compensate for antenna beam pointing errors on the spacecraft in real time. The first spaceborne demonstration is scheduled to be flown as an experiment on a 1982 Shuttle imaging radar mission (SIR-B). This paper describes the architecture and implementation characteristics of this initial spaceborne CCD SAR image processor.

  16. Potential usefulness of CCD imagers in astronomy

    NASA Technical Reports Server (NTRS)

    Mccord, T. B.; Bosel, J. P.

    1975-01-01

    Two dimensional detectors have been important in astronomy since the earliest days of the science. Recently, the requirements for greater photometric accuracy, sensitivity and spectral coverage have driven the search for better imaging devices. Electron beam readout devices with a variety of target materials and intensification schemes, including the SEC and silicon vidicons, have been used successfully. The CCD as an image detector has several potential advantages over electron beam readout devices; low noise, simple construction and geometric stability are among them.

  17. This is a CCD image

    NASA Technical Reports Server (NTRS)

    2002-01-01

    An 893nm filter which isolates absorption by methane gas was used. This filter makes high cloud features appear bright. North is at the top and west is to the right. Three white ovals which are not associated with the comet are visible across the central meridian. To the south and west of these white ovals the impact locations of two comet fragments are visible as bright spots. The spot due to comet fragment A is on the west limb and the spot due to fragment C is to the east of it. The black spot just below the north polar hood is the shadow of the Jovian moon Ganymede. This image was taken by Dr. Wayne Pryor (University of Colorado), Dr. Chan Na (Southwest Research Institute) and Dr. Anita Cochran (University of Texas).

  18. A Pipeline Tool for CCD Image Processing

    NASA Astrophysics Data System (ADS)

    Bell, Jon F.; Young, Peter J.; Roberts, William H.; Sebo, Kim M.

    MSSSO is part of a collaboration developing a wide field imaging CCD mosaic (WFI). As part of this project, we have developed a GUI based pipeline tool that is an integrated part of MSSSO's CICADA data acquisition environment and processes CCD FITS images as they are acquired. The tool is also designed to run as a stand alone program to process previously acquired data. IRAF tasks are used as the central engine, including the new NOAO mscred package for processing multi-extension FITS files. The STScI OPUS pipeline environment may be used to manage data and process scheduling. The Motif GUI was developed using SUN Visual Workshop. C++ classes were written to facilitate launching of IRAF and OPUS tasks. While this first version implements calibration processing up to and including flat field corrections, there is scope to extend it to other processing.

  19. Development of a CCD for ultraviolet imaging using a CCD photocathode combination

    NASA Technical Reports Server (NTRS)

    Collins, D. R.; Roberts, C. G.; Chan, W. W.; Rhines, W. C.; Barton, J. B.; Sobieski, S.

    1975-01-01

    CCD in the electron-in mode, coupled with a bi-alkali photocathode to produce UV photon conversion, provides the following desirable features: (1) high UV response of the bi-alkali photocathode; (2) excellent imaging quality of a CCD area array; and (3) high signal-to-noise ratio due to the EBS (electron bombarded silicon) gain of the CCD operating in a tube configuration. This paper describes the rationale and progress made in developing a CCD for use as an UV imager.

  20. Astrometrica: Astrometric data reduction of CCD images

    NASA Astrophysics Data System (ADS)

    Raab, Herbert

    2012-03-01

    Astrometrica is an interactive software tool for scientific grade astrometric data reduction of CCD images. The current version of the software is for the Windows 32bit operating system family. Astrometrica reads FITS (8, 16 and 32 bit integer files) and SBIG image files. The size of the images is limited only by available memory. It also offers automatic image calibration (Dark Frame and Flat Field correction), automatic reference star identification, automatic moving object detection and identification, and access to new-generation star catalogs (PPMXL, UCAC 3 and CMC-14), in addition to online help and other features. Astrometrica is shareware, available for use for a limited period of time (100 days) for free; special arrangements can be made for educational projects.

  1. The design of an advanced CCD timing generator

    NASA Astrophysics Data System (ADS)

    Cheng, Guimei; Wu, Songbo; Wan, Min; Bao, Bin; Deng, JueQiong; Duan, Jing

    2015-10-01

    This paper describes how to design and develop an advanced Charge Coupled Device (CCD) timing generator which can obtain high precise CCD output signals. Above all, theory of the design and implementation of CCD timing generator is introduced based on Field Programmable Gate Array (FPGA) devices in detail. Secondly, it studies and analyzes the influencing factors that the waveform of CCD driving timing signals have on qualities of CCD output signals, which contain duty-cycle of HCCD clock, positive width of RST, signal-skew and delays among these signals. Then some skills are presented to improve and optimize the design in the phase of coding, compiling and placement and routing, which include code constraint, incremental placement and so on. Finally, simulation and verification of the design are performed with simulation tools, and hardware tests are carried out and experiment results are proved by oscilloscope.

  2. CCD image acquisition for multispectral teledetection

    NASA Astrophysics Data System (ADS)

    Peralta-Fabi, R.; Peralta, A.; Prado, Jorge M.; Vicente, Esau; Navarette, M.

    1992-08-01

    A low cost high-reliability multispectral video system has been developed for airborne remote sensing. Three low weight CCD cameras are mounted together with a photographic camera in a keviar composite self-contained structure. The CCD cameras are remotely controlled have spectral filters (80 nm at 50 T) placed in front of their optical system and all cameras are aligned to capture the same image field. Filters may be changed so as to adjust spectral bands according to the object s reflectance properties but a set of bands common to most remote sensing aircraft and satellites are usually placed covering visible and near JR. This paper presents results obtained with this system and some comparisons as to the cost resolution and atmospheric correction advantages with respect to other more costly devices. Also a brief description of the Remotely Piloted Vehicle (RPV) project where the camera system will be mounted is given. The images so obtained replace the costlier ones obtained by satellites in severai specific applications. Other applications under development include fire monitoring identification of vegetation in the field and in the laboratory discrimination of objects by color for industrial applications and for geological and engineering surveys. 1.

  3. Method for eliminating artifacts in CCD imagers

    DOEpatents

    Turko, B.T.; Yates, G.J.

    1992-06-09

    An electronic method for eliminating artifacts in a video camera employing a charge coupled device (CCD) as an image sensor is disclosed. The method comprises the step of initializing the camera prior to normal read out and includes a first dump cycle period for transferring radiation generated charge into the horizontal register while the decaying image on the phosphor being imaged is being integrated in the photosites, and a second dump cycle period, occurring after the phosphor image has decayed, for rapidly dumping unwanted smear charge which has been generated in the vertical registers. Image charge is then transferred from the photosites and to the vertical registers and read out in conventional fashion. The inventive method allows the video camera to be used in environments having high ionizing radiation content, and to capture images of events of very short duration and occurring either within or outside the normal visual wavelength spectrum. Resultant images are free from ghost, smear and smear phenomena caused by insufficient opacity of the registers and, and are also free from random damage caused by ionization charges which exceed the charge limit capacity of the photosites. 3 figs.

  4. Method for eliminating artifacts in CCD imagers

    DOEpatents

    Turko, Bojan T.; Yates, George J.

    1992-01-01

    An electronic method for eliminating artifacts in a video camera (10) employing a charge coupled device (CCD) (12) as an image sensor. The method comprises the step of initializing the camera (10) prior to normal read out and includes a first dump cycle period (76) for transferring radiation generated charge into the horizontal register (28) while the decaying image on the phosphor (39) being imaged is being integrated in the photosites, and a second dump cycle period (78), occurring after the phosphor (39) image has decayed, for rapidly dumping unwanted smear charge which has been generated in the vertical registers (32). Image charge is then transferred from the photosites (36) and (38) to the vertical registers (32) and read out in conventional fashion. The inventive method allows the video camera (10) to be used in environments having high ionizing radiation content, and to capture images of events of very short duration and occurring either within or outside the normal visual wavelength spectrum. Resultant images are free from ghost, smear and smear phenomena caused by insufficient opacity of the registers (28) and (32), and are also free from random damage caused by ionization charges which exceed the charge limit capacity of the photosites (36) and (37).

  5. 8-megapixel thermoelectrically cooled CCD imaging system

    NASA Astrophysics Data System (ADS)

    Diercks, Alan H.; Angione, John; Stubbs, Christopher W.; Cook, Kem H.; Bowell, Edward; Koehn, Bruce W.; Nye, Ralph A.; Dodgen, Dave

    1995-03-01

    We are developing an astronomical imaging system which employs a thermoelectrically cooled focal plane consisting of two 'edge-buttable' Loral 2048 X 2048 pixel CCDs. To allow strip scanning, the columns of the CCDs are mutually aligned on a custom Kovar mount. The clocking and bias voltage levels for each CCD are independently adjustable, but both CCDs are operated synchronously. Each chip is read out from one output and measured at 14 bits with commercially available A/D converters at a rate of 250 kpixels/s, permitting scanning across the sky at up to 1000 deg2/hr (about twenty times faster than the equatorial sidereal rate) to a limiting magnitude (S/N equals 3) near V equals 19. The instrument will be used as part of the Lowell Observatory Near-Earth-Object Search (LONEOS) using a 57-cm Schmidt telescope at Lowell Observatory in Flagstaff, Arizona.

  6. UV-sensitive scientific CCD image sensors

    NASA Astrophysics Data System (ADS)

    Vishnevsky, Grigory I.; Kossov, Vladimir G.; Iblyaminova, A. F.; Lazovsky, Leonid Y.; Vydrevitch, Michail G.

    1997-06-01

    An investigation of probe laser irradiation interaction with substances containing in an environment has long since become a recognized technique for contamination detection and identification. For this purpose, a near and midrange-IR laser irradiation is traditionally used. However, as many works presented on last ecology monitoring conferences show, in addition to traditional systems, rapidly growing are systems with laser irradiation from near-UV range (250 - 500 nm). Use of CCD imagers is one of the prerequisites for this allowing the development of a multi-channel computer-based spectral research system. To identify and analyze contaminating impurities on an environment, such methods as laser fluorescence analysis, UV absorption and differential spectroscopy, Raman scattering are commonly used. These methods are used to identify a large number of impurities (petrol, toluene, Xylene isomers, SO2, acetone, methanol), to detect and identify food pathogens in real time, to measure a concentration of NH3, SO2 and NO in combustion outbursts, to detect oil products in a water, to analyze contaminations in ground waters, to define ozone distribution in the atmosphere profile, to monitor various chemical processes including radioactive materials manufacturing, heterogeneous catalytic reactions, polymers production etc. Multi-element image sensor with enhanced UV sensitivity, low optical non-uniformity, low intrinsic noise and high dynamic range is a key element of all above systems. Thus, so called Virtual Phase (VP) CCDs possessing all these features, seems promising for ecology monitoring spectral measuring systems. Presently, a family of VP CCDs with different architecture and number of pixels is developed and being manufactured. All CCDs from this family are supported with a precise slow-scan digital image acquisition system that can be used in various image processing systems in astronomy, biology, medicine, ecology etc. An image is displayed directly on a PC

  7. High-resolution CCD imagers using area-array CCD's for sensing spectral components of an optical line image

    NASA Technical Reports Server (NTRS)

    Elabd, Hammam (Inventor); Kosonocky, Walter F. (Inventor)

    1987-01-01

    CCD imagers with a novel replicated-line-imager architecture are abutted to form an extended line sensor. The sensor is preceded by optics having a slit aperture and having an optical beam splitter or astigmatic lens for projecting multiple line images through an optical color-discriminating stripe filter to the CCD imagers. A very high resolution camera suitable for use in a satellite, for example, is thus provided. The replicated-line architecture of the imager comprises an area-array CCD, successive rows of which are illuminated by replications of the same line segment, as transmitted by respective color filter stripes. The charge packets formed by accumulation of photoresponsive charge in the area-array CCD are read out row by row. Each successive row of charge packets is then converted from parallel to serial format in a CCD line register and its amplitude sensed to generate a line of output signal.

  8. Radiation events in astronomical CCD images

    NASA Astrophysics Data System (ADS)

    Smith, Alan R.; McDonald, Richard J.; Hurley, D. C.; Holland, Steven E.; Groom, Donald E.; Brown, William E.; Gilmore, David K.; Stover, Richard J.; Wei, Mingzhi

    2002-04-01

    The remarkable sensitivity of depleted silicon to ionizing radiation is a nuisance to astronomers. 'Cosmic rays' degrade images because of struck pixels, leading to modified observing strategies and the development of algorithms to remove the unwanted artifacts. In the new-generation CCD's with thick sensitive regions, cosmic-ray muons make recognizable straight tracks and there is enhanced sensitivity to ambient gamma radiation via Compton-scattered electrons ('worms'). Beta emitters inside the dewar, for example high-potassium glasses such as BK7 , also produce worm-like tracks. The cosmic-ray muon rate is irreducible and increases with altitude. The gamma rays are mostly by- products of 40K decay and the U and Th decay chains; these elements commonly appear as traces in concrete and other materials. The Compton recoil event rate can be reduced significantly by the choice of materials in the environment and dewar and by careful shielding. Telescope domes appear to have significantly lower rates than basement laboratories and Coude spectrograph rooms. Radiation sources inside the dewar can be eliminated by judicious choice of materials. Cosmogenic activation during high-altitude fights does not appear to be a problem. Our conclusion are supported by tests at the Lawrence Berkeley National Laboratory low-level counting facilities in Berkeley and at Oroville, California (180 m underground).

  9. Radiation events in astronomical CCD images

    SciTech Connect

    Smith, A.R.; McDonald, R.J.; Hurley, D.L.; Holland, S.E.; Groom, D.E.; Brown, W.E.; Gilmore, D.K.; Stover, R.J.; Wei, M.

    2001-12-18

    The remarkable sensitivity of depleted silicon to ionizing radiation is a nuisance to astronomers. ''Cosmic rays'' degrade images because of struck pixels, leading to modified observing strategies and the development of algorithms to remove the unwanted artifacts. In the new-generation CCD's with thick sensitive regions, cosmic-ray muons make recognizable straight tracks and there is enhanced sensitivity to ambient gamma radiation via Compton-scattered electrons (''worms''). Beta emitters inside the dewar, for example high-potassium glasses such as BK7, also produce worm-like tracks. The cosmic-ray muon rate is irreducible and increases with altitude. The gamma rays are mostly by-products of the U and Th decay chains; these elements always appear as traces in concrete and other materials. The Compton recoil event rate can be reduced significantly by the choice of materials in the environment and dewar and by careful shielding. Telescope domes appear to be significantly cleaner than basement laboratories and Coude spectrograph rooms. Radiation sources inside the dewar can be eliminated by judicious choice of materials. Cosmogenic activation during high-altitude flights does not appear to be a problem. Our conclusions are supported by tests at the Lawrence Berkeley National Laboratory low-level counting facilities in Berkeley and at Oroville, California (180 m underground).

  10. Low-noise video amplifiers for imaging CCD's

    NASA Technical Reports Server (NTRS)

    Scinicariello, F.

    1976-01-01

    Various techniques were developed which enable the CCD (charge coupled device) imaging array user to obtain optimum performance from the device. A CCD video channel was described, and detector-preamplifier interface requirements were examined. A noise model for the system was discussed at length and laboratory data presented and compared to predicted results.

  11. Correlation and image compression for limited-bandwidth CCD.

    SciTech Connect

    Thompson, Douglas G.

    2005-07-01

    As radars move to Unmanned Aerial Vehicles with limited-bandwidth data downlinks, the amount of data stored and transmitted with each image becomes more significant. This document gives the results of a study to determine the effect of lossy compression in the image magnitude and phase on Coherent Change Detection (CCD). We examine 44 lossy compression types, plus lossless zlib compression, and test each compression method with over 600 CCD image pairs. We also derive theoretical predictions for the correlation for most of these compression schemes, which compare favorably with the experimental results. We recommend image transmission formats for limited-bandwidth programs having various requirements for CCD, including programs which cannot allow performance degradation and those which have stricter bandwidth requirements at the expense of CCD performance.

  12. CCD operation using the High Speed Imager Test Station

    SciTech Connect

    Albright, K.L.; Yates, G.J.; King, N.S.P.; McDonald, T.E.; Turko, B.T.

    1992-12-01

    The use of a high-speed (up to 100 MHz.) programmable pattern generator and special clock driver/translator circuits for clocking solid-state multiple output imagers is discussed. A specific example of clocking a developmental 256 x 512 two-port CCD is illustrated. Reference to a prior report of clocking an eight-port CCD is included. Future use in clocking a CID imager is discussed.

  13. CCD operation using the High Speed Imager Test Station

    SciTech Connect

    Albright, K.L.; Yates, G.J.; King, N.S.P.; McDonald, T.E. ); Turko, B.T. )

    1992-01-01

    The use of a high-speed (up to 100 MHz.) programmable pattern generator and special clock driver/translator circuits for clocking solid-state multiple output imagers is discussed. A specific example of clocking a developmental 256 x 512 two-port CCD is illustrated. Reference to a prior report of clocking an eight-port CCD is included. Future use in clocking a CID imager is discussed.

  14. Based on line scan CCD print image detection system

    NASA Astrophysics Data System (ADS)

    Zhang, Lifeng; Xie, Kai; Li, Tong

    2015-12-01

    In this paper, a new method based on machine vision is proposed for the defects of the traditional manual inspection of the quality of printed matter. With the aid of on line array CCD camera for image acquisition, using stepper motor as a sampling of drive circuit. Through improvement of driving circuit, to achieve the different size or precision image acquisition. In the terms of image processing, the standard image registration algorithm then, because of the characteristics of CCD-image acquisition, rigid body transformation is usually used in the registration, so as to achieve the detection of printed image.

  15. CCD image data acquisition system for optical astronomy.

    NASA Astrophysics Data System (ADS)

    Bhat, P. N.; Patnaik, K.; Kembhavi, A. K.; Patnaik, A. R.; Prabhu, T. P.

    1990-11-01

    A complete image processing system based on a charge coupled device (CCD) has been developed at TIFR, Bombay, for use in optical astronomy. The system consists of a P-8600/B GEC CCD chip, a CCD controller, a VAX 11/725 mini-computer to carry out the image acquisition and display on a VS-11 monitor. All the necessary software and part of the hardware were developed locally, integrated together and installed at the Vainu Bappu Observatory at Kavalur. CCD as an imaging device and its advantages over the conventional photographic plate is briefly reviewed. The acquisition system is described in detail. The preliminary results are presented and the future research programme is outlined.

  16. Collection and processing data for high quality CCD images.

    SciTech Connect

    Doerry, Armin Walter

    2007-03-01

    Coherent Change Detection (CCD) with Synthetic Aperture Radar (SAR) images is a technique whereby very subtle temporal changes can be discerned in a target scene. However, optimal performance requires carefully matching data collection geometries and adjusting the processing to compensate for imprecision in the collection geometries. Tolerances in the precision of the data collection are discussed, and anecdotal advice is presented for optimum CCD performance. Processing considerations are also discussed.

  17. Application of the CCD camera in medical imaging

    NASA Astrophysics Data System (ADS)

    Chu, Wei-Kom; Smith, Chuck; Bunting, Ralph; Knoll, Paul; Wobig, Randy; Thacker, Rod

    1999-04-01

    Medical fluoroscopy is a set of radiological procedures used in medical imaging for functional and dynamic studies of digestive system. Major components in the imaging chain include image intensifier that converts x-ray information into an intensity pattern on its output screen and a CCTV camera that converts the output screen intensity pattern into video information to be displayed on a TV monitor. To properly respond to such a wide dynamic range on a real-time basis, such as fluoroscopy procedure, are very challenging. Also, similar to all other medical imaging studies, detail resolution is of great importance. Without proper contrast, spatial resolution is compromised. The many inherent advantages of CCD make it a suitable choice for dynamic studies. Recently, CCD camera are introduced as the camera of choice for medical fluoroscopy imaging system. The objective of our project was to investigate a newly installed CCD fluoroscopy system in areas of contrast resolution, details, and radiation dose.

  18. The Dark Energy Survey CCD imager design

    SciTech Connect

    Cease, H.; DePoy, D.; Diehl, H.T.; Estrada, J.; Flaugher, B.; Guarino, V.; Kuk, K.; Kuhlmann, S.; Schultz, K.; Schmitt, R.L.; Stefanik, A.; /Fermilab /Ohio State U. /Argonne

    2008-06-01

    The Dark Energy Survey is planning to use a 3 sq. deg. camera that houses a {approx} 0.5m diameter focal plane of 62 2kx4k CCDs. The camera vessel including the optical window cell, focal plate, focal plate mounts, cooling system and thermal controls is described. As part of the development of the mechanical and cooling design, a full scale prototype camera vessel has been constructed and is now being used for multi-CCD readout tests. Results from this prototype camera are described.

  19. Overlapping-Gate Ccd Imagers On Gallium Arsenide

    NASA Astrophysics Data System (ADS)

    Kosel, P. B.; Katzer, D. S.; Poore, R. E...

    1987-01-01

    Charge-coupled device (CCD) imagers have been fabricated on gallium arsenide (GaAs) with very closely spaced (<100nm) Schottky-barrier metal electrodes. The short interelectrode spacing was achieved by using anodic oxidation in an ethylene glycol based electrolyte. All the active device regions of the CCD imagers were formed by silicon implantation into semi-insulating GaAs substrates followed by rapid thermal activation. The photodetectors were Schottky barrier diodes formed with thin aluminum metal anodes over silicon-implanted active regions in the semi-insulating substrate. The detectors formed a linear array along one side of the CCD channel and a three-phase transfer electrode structure was used. The imagers have been tested with front side illumination at clocking speeds up to 25 MHz.

  20. Development of CCD imaging sensors for space applications, phase 1

    NASA Technical Reports Server (NTRS)

    Antcliffe, G. A.

    1975-01-01

    The results of an experimental investigation to develop a large area charge coupled device (CCD) imager for space photography applications are described. Details of the design and processing required to achieve 400 X 400 imagers are presented together with a discussion of the optical characterization techniques developed for this program. A discussion of several aspects of large CCD performance is given with detailed test reports. The areas covered include dark current, uniformity of optical response, square wave amplitude response, spectral responsivity and dynamic range.

  1. Compression of CCD raw images for digital still cameras

    NASA Astrophysics Data System (ADS)

    Sriram, Parthasarathy; Sudharsanan, Subramania

    2005-03-01

    Lossless compression of raw CCD images captured using color filter arrays has several benefits. The benefits include improved storage capacity, reduced memory bandwidth, and lower power consumption for digital still camera processors. The paper discusses the benefits in detail and proposes the use of a computationally efficient block adaptive scheme for lossless compression. Experimental results are provided that indicate that the scheme performs well for CCD raw images attaining compression factors of more than two. The block adaptive method also compares favorably with JPEG-LS. A discussion is provided indicating how the proposed lossless coding scheme can be incorporated into digital still camera processors enabling lower memory bandwidth and storage requirements.

  2. CCD image sensor induced error in PIV applications

    NASA Astrophysics Data System (ADS)

    Legrand, M.; Nogueira, J.; Vargas, A. A.; Ventas, R.; Rodríguez-Hidalgo, M. C.

    2014-06-01

    The readout procedure of charge-coupled device (CCD) cameras is known to generate some image degradation in different scientific imaging fields, especially in astrophysics. In the particular field of particle image velocimetry (PIV), widely extended in the scientific community, the readout procedure of the interline CCD sensor induces a bias in the registered position of particle images. This work proposes simple procedures to predict the magnitude of the associated measurement error. Generally, there are differences in the position bias for the different images of a certain particle at each PIV frame. This leads to a substantial bias error in the PIV velocity measurement (˜0.1 pixels). This is the order of magnitude that other typical PIV errors such as peak-locking may reach. Based on modern CCD technology and architecture, this work offers a description of the readout phenomenon and proposes a modeling for the CCD readout bias error magnitude. This bias, in turn, generates a velocity measurement bias error when there is an illumination difference between two successive PIV exposures. The model predictions match the experiments performed with two 12-bit-depth interline CCD cameras (MegaPlus ES 4.0/E incorporating the Kodak KAI-4000M CCD sensor with 4 megapixels). For different cameras, only two constant values are needed to fit the proposed calibration model and predict the error from the readout procedure. Tests by different researchers using different cameras would allow verification of the model, that can be used to optimize acquisition setups. Simple procedures to obtain these two calibration values are also described.

  3. Development of CCD Imaging System Using Thermoelectric Cooling Method

    NASA Astrophysics Data System (ADS)

    Park, Youngsik; Lee, Ho Jin; Han, Wonyong; Nam, Uk-Won; Lee, Yong-Sam

    2000-06-01

    We developed low light CCD imaging system using thermoelectric cooling method collaboration with a company to design a commercial model. It consists of Kodak KAF-0401E (768x512 pixels) CCD chip,thermoelectric module manufactured by Thermotek. This TEC system can reach an operative temperature of -25deg. We employed an Uniblitz VS25S shutter and it has capability a minimum exposure time 80ms. The system components are an interface card using a Korea Astronomy Observatory (hereafter KAO) ISA bus controller, image acquisition with AD9816 chip, that is 12bit video processor. The performance test with this imaging system showed good operation within the initial specification of our design. It shows a dark current less than 0.4e-/pixel/sec at a temperature of -10deg, a linearity 99.9+/-0.1%, gain 4.24e-adu, and system noise is 25.3e- (rms). For low temperature CCD operation, we designed a TEC, which uses a one-stage peltier module and forced air heat exchanger. This TEC imaging system enables accurate photometry (+/-0.01mag) even though the CCD is not at 'conventional' cryogenic temperatures (140K). The system can be a useful instrument for any other imaging applications. Finally, with this system, we obtained several images of astronomical objects for system performance tests.

  4. Computer-aided analysis of CCD linear image sensors

    NASA Technical Reports Server (NTRS)

    Prince, S. S.

    1976-01-01

    Special test equipment and techniques to collect and process image information from charge coupled devices (CCDs) by digital computer were reviewed. The video channel was traced from the CCD to the direct memory access bus of the Interdata Computer. Software was developed to evaluate and characterize a CCD for (1) dark signal versus temperature relationship, (2) calculation of temporal noise magnitude and noise shape for each pixel, (3) spatial noise into the video chain due to dark signal, (4) response versus illumination relationship (gamma), (5) response versus wavelength of illumination (spectral), (6) optimization of forcing functions, and (7) evaluation of an image viewed by a CCD. The basic software differences and specific examples of each program operating on real data are presented.

  5. Large-area CCD imagers for spacecraft applications

    NASA Technical Reports Server (NTRS)

    Antcliffe, G. A.; Hornbeck, L. J.; Younse, J. M.; Barton, J. B.; Collins, D. R.

    1975-01-01

    Backside illuminated CCD imagers with 100 x 160 resolution elements have been fabricated using double level metal technology. Detailed study of the optical performance of such arrays has been performed between 24 C and -40 C using data rates from 10 kHz to 1 MHz. A 400 x 400 array is presently being fabricated.

  6. Simulations of the STIS CCD clear imaging mode PSF

    NASA Technical Reports Server (NTRS)

    Cornett, R. H.; Grusczak, A.; Ftaclas, C.; Heap, S. R.; Woodgate, B. E.

    1997-01-01

    Detailed understanding of the properties of the point-spread function (PSF) of Space Telescope Imaging Spectrograph (STIS) imaging modes is necessary to separate real effects of geometrically complex astronomical sources, such as protoplanetary disks surrounding bright stars, from instrumental effects, such as scattering and diffraction. In order to investigate STIS imaging properties we have numerically simulated broadband stellar PSFs generated by STIS in CCD clear imaging mode, including the effects of the Lyot stop and the coronagraphic wedges. The input spectrum is a stellar model atmosphere of the appropriate spectral type, convolved with the pre-flight STIS CCD response function. The PSF modeler generates broadband PSFs by co-adding weighted monochromatic PSFs across the waveband.

  7. Advanced imaging system

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This document describes the Advanced Imaging System CCD based camera. The AIS1 camera system was developed at Photometric Ltd. in Tucson, Arizona as part of a Phase 2 SBIR contract No. NAS5-30171 from the NASA/Goddard Space Flight Center in Greenbelt, Maryland. The camera project was undertaken as a part of the Space Telescope Imaging Spectrograph (STIS) project. This document is intended to serve as a complete manual for the use and maintenance of the camera system. All the different parts of the camera hardware and software are discussed and complete schematics and source code listings are provided.

  8. A large field CCD system for quantitative imaging of microarrays

    PubMed Central

    Hamilton, G.; Brown, N.; Oseroff, V.; Huey, B.; Segraves, R.; Sudar, D.; Kumler, J.; Albertson, D.; Pinkel, D.

    2006-01-01

    We describe a charge-coupled device (CCD) imaging system for microarrays capable of acquiring quantitative, high dynamic range images of very large fields. Illumination is supplied by an arc lamp, and filters are used to define excitation and emission bands. The system is linear down to fluorochrome densities ≪1 molecule/µm2. The ratios of the illumination intensity distributions for all excitation wavelengths have a maximum deviation ∼±4% over the object field, so that images can be analyzed without computational corrections for the illumination pattern unless higher accuracy is desired. Custom designed detection optics produce achromatic images of the spectral region from ∼ 450 to ∼750 nm. Acquisition of a series of images of multiple fluorochromes from multiple arrays occurs under computer control. The version of the system described in detail provides images of 20 mm square areas using a 27 mm square, 2K × 2K pixel, cooled CCD chip with a well depth of ∼105 electrons, and provides ratio measurements accurate to a few percent over a dynamic range in intensity >1000. Resolution referred to the sample is 10 µm, sufficient for obtaining quantitative multicolor images from >30 000 array elements in an 18 mm × 18 mm square. PMID:16670425

  9. Event-Driven Random-Access-Windowing CCD Imaging System

    NASA Technical Reports Server (NTRS)

    Monacos, Steve; Portillo, Angel; Ortiz, Gerardo; Alexander, James; Lam, Raymond; Liu, William

    2004-01-01

    A charge-coupled-device (CCD) based high-speed imaging system, called a realtime, event-driven (RARE) camera, is undergoing development. This camera is capable of readout from multiple subwindows [also known as regions of interest (ROIs)] within the CCD field of view. Both the sizes and the locations of the ROIs can be controlled in real time and can be changed at the camera frame rate. The predecessor of this camera was described in High-Frame-Rate CCD Camera Having Subwindow Capability (NPO- 30564) NASA Tech Briefs, Vol. 26, No. 12 (December 2002), page 26. The architecture of the prior camera requires tight coupling between camera control logic and an external host computer that provides commands for camera operation and processes pixels from the camera. This tight coupling limits the attainable frame rate and functionality of the camera. The design of the present camera loosens this coupling to increase the achievable frame rate and functionality. From a host computer perspective, the readout operation in the prior camera was defined on a per-line basis; in this camera, it is defined on a per-ROI basis. In addition, the camera includes internal timing circuitry. This combination of features enables real-time, event-driven operation for adaptive control of the camera. Hence, this camera is well suited for applications requiring autonomous control of multiple ROIs to track multiple targets moving throughout the CCD field of view. Additionally, by eliminating the need for control intervention by the host computer during the pixel readout, the present design reduces ROI-readout times to attain higher frame rates. This camera (see figure) includes an imager card consisting of a commercial CCD imager and two signal-processor chips. The imager card converts transistor/ transistor-logic (TTL)-level signals from a field programmable gate array (FPGA) controller card. These signals are transmitted to the imager card via a low-voltage differential signaling (LVDS) cable

  10. CCD Image Identification: An Artificial Neural Networks Approach

    NASA Astrophysics Data System (ADS)

    El-Bassuny Alawy, A.; et al.

    An Artificial Neural Network (ANN) technique in supervised mode has been developed to classify stellar, cosmic and noise identities on CCD frames. It has been implemented and coded in the C language for Personal Computers users. Its learning factors and training (cumulative, rms and decision) errors have been investigated. Two sets comprising a few hundred images of stars, cosmic rays and noise of different levels were adopted to train and test the algorithm developed. The present approach has been applied on a CCD frame of the star cluster M67. The results were discussed in comparison with those obtained from DAOPHOTII code out of the same frame. It has been shown that the present approach is fast, precise, efficient and reliable as well as requiring no prior input data for identification.

  11. Line scan CCD image processing for biomedical application

    NASA Astrophysics Data System (ADS)

    Lee, Choon-Young; Yan, Lei; Lee, Sang-Ryong

    2010-02-01

    Blood samples are frequently analyzed for the blood disorders or other diseases in the research and clinic applications. Most of the analyses are related to blood cell counts and blood cell sizes. In this paper, the line scan CCD imaging system is developed, which is based on the Texas Instruments' TMS320C6416T (DSP6416), a high performance digital signal processor and Altera's Field programmable Gate Array (FPGA) EP3C25F324. It is used to acquire and process the images of blood cells for counting the number of cells, sizing and positioning them. The cell image is captured by line scan CCD sensor and then the digital image data converted by Analogue Front-End (AFE) are transferred into FPGA, after pre-processing they are transferred into DSP6416 through the interface of First In First Out (FIFO) in FPGA and External Memory Interfaces (EMIF) of DSP6416. Then the image data are processed in DSP6416. Experimental results show that this system is useful and efficient.

  12. Recent CCD Images of Hubble's Variable Nebula (NGC 2261)

    NASA Astrophysics Data System (ADS)

    Meisel, D.; Dykstra, W.; Schulitz, F.

    1992-05-01

    Four CCD exposures of Hubble's Variable Nebula were taken with the RIT Kodak KF-4200 array using the 0.6m Hawaii telescope at Mauna Kea. The field of view was 5' x 7' of arc with a resolution of 0.3" per pixel. The effective wavelengths were v 5300A, r 6200A, i 8000A and ii 9000A. Preliminary image processing has been done on Macintosh IIfxs and LCs using NIH Image1.44b20 and has revealed considerable detail in the dust cloud, but no obvious obscuration features as seen at past epochs. Final image processing is continuing on Sun workstations using IRAF and SAO Image. Differences of structure between the wavelength bands and comparisons between images at other epochs, CO maps, and polarimetry will be discussed.

  13. 3CCD image segmentation and edge detection based on MATLAB

    NASA Astrophysics Data System (ADS)

    He, Yong; Pan, Jiazhi; Zhang, Yun

    2006-09-01

    This research aimed to identify weeds from crops in early stage in the field operation by using image-processing technology. As 3CCD images offer greater binary value difference between weed and crop section than ordinary digital images taken by common cameras. It has 3 channels (green, red, ifred) which takes a snap-photo of the same area, and the three images can be composed into one image, which facilitates the segmentation of different areas. By the application of image-processing toolkit on MATLAB, the different areas in the image can be segmented clearly. As edge detection technique is the first and very important step in image processing, The different result of different processing method was compared. Especially, by using the wavelet packet transform toolkit on MATLAB, An image was preprocessed and then the edge was extracted, and getting more clearly cut image of edge. The segmentation methods include operations as erosion, dilation and other algorithms to preprocess the images. It is of great importance to segment different areas in digital images in field real time, so as to be applied in precision farming, to saving energy and herbicide and many other materials. At present time Large scale software as MATLAB on PC was used, but the computation can be reduced and integrated into a small embed system, which means that the application of this technique in agricultural engineering is feasible and of great economical value.

  14. Producing CCD imaging sensor with flashed backside metal film

    NASA Technical Reports Server (NTRS)

    Janesick, James R. (Inventor)

    1988-01-01

    A backside illuminated CCD imaging sensor for reading out image charges from wells of the array of pixels is significantly improved for blue, UV, far UV and low energy x-ray wavelengths (1-5000.ANG.) by so overthinning the backside as to place the depletion edge at the surface and depositing a thin transparent metal film of about 10.ANG. on a native-quality oxide film of less than about 30.ANG. grown on the thinned backside. The metal is selected to have a higher work function than that of the semiconductor to so bend the energy bands (at the interface of the semiconductor material and the oxide film) as to eliminate wells that would otherwise trap minority carriers. A bias voltage may be applied to extend the frontside depletion edge to the interface of the semiconductor material with the oxide film in the event there is not sufficient thinning. This metal film (flash gate), which improves and stabilizes the quantum efficiency of a CCD imaging sensor, will also improve the QE of any p-n junction photodetector.

  15. CCD imaging sensor with flashed backside metal film

    NASA Technical Reports Server (NTRS)

    Janesick, James R. (Inventor)

    1991-01-01

    A backside illuminated CCD imaging sensor for reading out image charges from wells of the array of pixels is significantly improved for blue, UV, far UV and low energy x-ray wavelengths (1-5000.ANG.) by so overthinning the backside as to place the depletion edge at the surface and depositing a thin transparent metal film of about 10.ANG. on a native-quality oxide film of less than about 30.ANG. grown on the thinned backside. The metal is selected to have a higher work function than that of the semiconductor to so bend the energy bands (at the interface of the semiconductor material and the oxide film) as to eliminate wells that would otherwise trap minority carriers. A bias voltage may be applied to extend the frontside depletion edge to the interface of the semiconductor material with the oxide film in the event there is not sufficient thinning. This metal film (flash gate), which improves and stabilizes the quantum efficiency of a CCD imaging sensor, will also improve the QE of any p-n junction photodetector.

  16. CCD detector development projects by the Beamline Technical Support Group at the Advanced Photon Source

    NASA Astrophysics Data System (ADS)

    Lee, John H.; Fernandez, Patricia; Madden, Tim; Molitsky, Michael; Weizeorick, John

    2007-11-01

    This paper will describe two ongoing detector projects being developed by the Beamline Technical Support Group at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The first project is the design and construction of two detectors: a single-CCD system and a two-by-two Mosaic CCD camera for Small-Angle X-ray Scattering (SAXS). Both of these systems utilize the Kodak KAF-4320E CCD coupled to fiber optic tapers, custom mechanical hardware, electronics, and software developed at ANL. The second project is a Fast-CCD (FCCD) detector being developed in a collaboration between ANL and Lawrence Berkeley National Laboratory (LBNL). This detector will use ANL-designed readout electronics and a custom LBNL-designed CCD, with 480×480 pixels and 96 outputs, giving very fast readout.

  17. CCD detector development projects by the beamline technical support group at the Advanced Photon Source.

    SciTech Connect

    Lee, J. H.; Fernandez, P.; Madden, T.; Molitsky, M.; Weizeorick, J.

    2007-11-11

    This paper will describe two ongoing detector projects being developed by the Beamline Technical Support Group at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The first project is the design and construction of two detectors: a single-CCD system and a two-by-two Mosaic CCD camera for Small-Angle X-ray Scattering (SAXS). Both of these systems utilize the Kodak KAF-4320E CCD coupled to fiber optic tapers, custom mechanical hardware, electronics, and software developed at ANL. The second project is a Fast-CCD (FCCD) detector being developed in a collaboration between ANL and Lawrence Berkeley National Laboratory (LBNL). This detector will use ANL-designed readout electronics and a custom LBNL-designed CCD, with 480 x 480 pixels and 96 outputs, giving very fast readout.

  18. Matching a curved focal plane with CCD's - Wide field imaging of glancing incidence X-ray telescopes

    NASA Technical Reports Server (NTRS)

    Nousek, J. A.; Garmire, G. P.; Ricker, G. R.; Bautz, M. W.; Levine, A. M.; Collins, S. A.

    1987-01-01

    The design of a wide field imaging camera suitable for use with a glancing incidence X-ray telescope is complicated by the sharply concave nature of the optimum focal surface of such a telescope. Such a camera made up of a mosaic of CCDs is being designed which is intended for flight aboard the Advanced X-ray Astrophysics Facility (AXAF). The design rationale and tradeoffs are discussed, and the layout for the imaging CCD array is presented. The related issue of optimizing performance of transmission objective gratings is also discussed, and the array of CCD orientations suitable for this problem is presented.

  19. Large area CCD image sensors for scientific applications

    NASA Technical Reports Server (NTRS)

    Blouke, M. M.; Heidtmann, D. L.; Corrie, B.; Lust, M. L.; Janesick, J. R.

    1985-01-01

    The designs of the 512 x 512 pixel and 2048 x 2048 pixel CCD sensors developed for scientific imaging are described. Both sensors are manufactured using the three phase, three level polysilicon gate technology, and the architecture of the chips is series-parallel-series. The components of the two different on-chip amplifiers are examined. The sensors are thinned and operated in the back side illumination mode to ensure the highest quantum efficiency. The performances of a number of front side illuminated devices and two thinned rear illuminated chips are evaluated. It is observed that the sensors equal or exceed their proposed charge transfer efficiency of 0.99999, the noise level of 2 e- and 20 e- at 50 kp/s, the quantum efficiency of 40 percent at 400 microns and 70 percent at 700 microns, and of the well capacity of greater than 500 ke-/pixel.

  20. System for control of cooled CCD and image data processing for plasma spectroscopy

    SciTech Connect

    Mimura, M.; Kakeda, T.; Inoko, A.

    1995-12-31

    A Spectroscopic measurement system which has a spacial resolution is important for plasma study. This is especially true for a measurement of a plasma without axial symmetry like the LHD-plasma. Several years ago, we developed an imaging spectroscopy system using a CCD camera and an image-memory board of a personal computer. It was very powerful to study a plasma-gas interaction phenomena. In which system, however, an ordinary CCD was used so that the dark-current noise of the CCD prevented to measure dark spectral lines. Recently, a cooled CCD system can be obtained for the high sensitivity measurement. But such system is still very expensive. The cooled CCD itself as an element can be purchased cheaply, because amateur agronomists began to use it to take a picture of heavenly bodies. So we developed an imaging spectroscopy system using such a cheap cooled CCD for plasma experiment.

  1. A new testing method of SNR for cooled CCD imaging camera based on stationary wavelet transform

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Liu, Qianshun; Yu, Feihong

    2013-08-01

    Cooled CCD (charge coupled device) imaging camera has found wide application in the field of astronomy, color photometry, spectroscopy, medical imaging, densitometry, chemiluminescence and epifluorescence imaging. A Cooled CCD (CCCD) imaging camera differs from traditional CCD/CMOS imaging camera in that Cooled CCD imaging camera can get high resolution image even in the low illumination environment. SNR (signal noise ratio) is most popular parameter of digital image quality evaluation. Many researchers have proposed various SNR testing methods for traditional CCD imaging camera, however, which is seldom suitable to Cooled CCD imaging camera because of different main noise source. In this paper, a new testing method of SNR is proposed to evaluate the quality of image captured by Cooled CCD. Stationary Wavelet Transform (SWT) is introduced in the testing method for getting more exact image SNR value. The method proposed take full advantage of SWT in the image processing, which makes the experiment results accuracy and reliable. To further refining SNR testing results, the relation between SNR and integration time is also analyzed in this article. The experimental results indicate that the testing method proposed accords with the SNR model of CCCD. In addition, the testing values for one system are about one value, which show that the proposed testing method is robust.

  2. 32-megapixel dual-color CCD imaging system

    NASA Astrophysics Data System (ADS)

    Stubbs, Christopher W.; Marshall, Stuart; Cook, Kenneth H.; Hills, Robert F.; Noonan, Joseph; Akerlof, Carl W.; Alcock, Charles R.; Axelrod, Timothy S.; Bennett, D.; Dagley, K.; Freeman, K. C.; Griest, Kim; Park, Hye-Sook; Perlmutter, Saul; Peterson, Bruce A.; Quinn, Peter J.; Rodgers, A. W.; Sosin, C.; Sutherland, W. J.

    1993-07-01

    We have developed an astronomical imaging system that incorporates a total of eight 2048 X 2048 pixel CCDs into two focal planes, to allow simultaneous imaging in two colors. Each focal plane comprises four 'edge-buttable' detector arrays, on custom Kovar mounts. The clocking and bias voltage levels for each CCD are independently adjustable, but all the CCDs are operated synchronously. The sixteen analog outputs (two per chip) are measured at 16 bits with commercially available correlated double sampling A/D converters. The resulting 74 MBytes of data per frame are transferred over fiber optic links into dual-ported VME memory. The total readout time is just over one minute. We obtain read noise ranging from 6.5 e- to 10 e- for the various channels when digitizing at 34 Kpixels/sec, with full well depths (MPP mode) of approximately 100,000 e- per 15 micrometers X 15 micrometers pixel. This instrument is currently being used in a search of gravitational microlensing from compact objects in our Galactic halo, using the newly refurbished 1.3 m telescope at the Mt. Stromlo Observatory, Australia.

  3. Image restoration for interlaced scan CCD image with space-variant motion blurs

    NASA Astrophysics Data System (ADS)

    Peng, Zhao; Guo-Qiang, Ni; Ting-Fa, Xu

    2010-09-01

    When the speeds of objects in a scene exceed the temporal resolution of the camera shutter, motion blurs will occur. Since objects are often moving in different directions at different speeds, the degradation of a CCD image is often characterized by space-variant motion blurs. Image restoration algorithms for space-variant motion blurs are available for progressive scan CCD images, but not for interlaced scan images. To address the space-variant image restoration for interlaced scan images, a novel three-step image restoration scheme is proposed. Firstly, one interlaced scan image is divided into odd field and even field images. Secondly, these two field images are further segmented into rectangular blocks and the motion vectors are computed based on these rectangular blocks using an efficient block matching algorithm. Thirdly, image restoration is performed using a blind deconvolution algorithm in the odd or even field image. The final restored image is obtained by combining the restored odd and even field images. The scheme is illustrated by restoring a space-variant blurred moving vehicle image and a synthetic blurred image.

  4. Electron multiplication CCD detector technology advancement for the WFIRST-AFTA coronagraph

    NASA Astrophysics Data System (ADS)

    Harding, Leon K.; Demers, Richard T.; Hoenk, Michael; Peddada, Pavani; Nemati, Bijan; Cherng, Michael; Michaels, Darren; Loc, Anthony; Bush, Nathan; Hall, David; Murray, Neil; Gow, Jason; Burgon, Ross; Holland, Andrew; Reinheimer, Alice; Jorden, Paul R.; Jordan, Douglas

    2015-11-01

    The WFIRST-AFTA (Wide Field InfraRed Survey Telescope-Astrophysics Focused Telescope Asset) is a NASA space observatory. It will host two major astronomical instruments: a wide-field imager (WFI) to search for dark energy and carry out wide field near infrared (NIR) surveys, and a coronagraph instrument (CGI) to image and spectrally characterize extrasolar planets. In this paper, we discuss the work that has been carried out at JPL in advancing Electron Multiplying CCD (EMCCD) technology to higher flight maturity, with the goal of reaching a NASA technology readiness level of 6 (TRL-6) by early-to-mid 2016. The EMCCD has been baselined for both the coronagraph's imager and integral field spectrograph (IFS) based on its sub-electron noise performance at extremely low flux levels - the regime where the AFTA CGI will operate. We present results from a study that fully characterizes the beginning of life performance of the EMCCD. We also discuss, and present initial results from, a recent radiation test campaign that was designed and carried out to mimic the conditions of the WFIRST-AFTA space environment in an L2 orbit, where we sought to assess the sensor's end of life performance, particularly degradation of its charge transfer efficiency, in addition to other parameters such as dark current, electron multiplication gain, clock induced charge and read noise.

  5. Experimental Comparison of the High-Speed Imaging Performance of an EM-CCD and sCMOS Camera in a Dynamic Live-Cell Imaging Test Case

    PubMed Central

    Beier, Hope T.; Ibey, Bennett L.

    2014-01-01

    The study of living cells may require advanced imaging techniques to track weak and rapidly changing signals. Fundamental to this need is the recent advancement in camera technology. Two camera types, specifically sCMOS and EM-CCD, promise both high signal-to-noise and high speed (>100 fps), leaving researchers with a critical decision when determining the best technology for their application. In this article, we compare two cameras using a live-cell imaging test case in which small changes in cellular fluorescence must be rapidly detected with high spatial resolution. The EM-CCD maintained an advantage of being able to acquire discernible images with a lower number of photons due to its EM-enhancement. However, if high-resolution images at speeds approaching or exceeding 1000 fps are desired, the flexibility of the full-frame imaging capabilities of sCMOS is superior. PMID:24404178

  6. Design of area array CCD image acquisition and display system based on FPGA

    NASA Astrophysics Data System (ADS)

    Li, Lei; Zhang, Ning; Li, Tianting; Pan, Yue; Dai, Yuming

    2014-09-01

    With the development of science and technology, CCD(Charge-coupled Device) has been widely applied in various fields and plays an important role in the modern sensing system, therefore researching a real-time image acquisition and display plan based on CCD device has great significance. This paper introduces an image data acquisition and display system of area array CCD based on FPGA. Several key technical challenges and problems of the system have also been analyzed and followed solutions put forward .The FPGA works as the core processing unit in the system that controls the integral time sequence .The ICX285AL area array CCD image sensor produced by SONY Corporation has been used in the system. The FPGA works to complete the driver of the area array CCD, then analog front end (AFE) processes the signal of the CCD image, including amplification, filtering, noise elimination, CDS correlation double sampling, etc. AD9945 produced by ADI Corporation to convert analog signal to digital signal. Developed Camera Link high-speed data transmission circuit, and completed the PC-end software design of the image acquisition, and realized the real-time display of images. The result through practical testing indicates that the system in the image acquisition and control is stable and reliable, and the indicators meet the actual project requirements.

  7. Failure Analysis of CCD Image Sensors Using SQUID and GMR Magnetic Current Imaging

    NASA Technical Reports Server (NTRS)

    Felt, Frederick S.

    2005-01-01

    During electrical testing of a Full Field CCD Image Senor, electrical shorts were detected on three of six devices. These failures occurred after the parts were soldered to the PCB. Failure analysis was performed to determine the cause and locations of these failures on the devices. After removing the fiber optic faceplate, optical inspection was performed on the CCDs to understand the design and package layout. Optical inspection revealed that the device had a light shield ringing the CCD array. This structure complicated the failure analysis. Alternate methods of analysis were considered, including liquid crystal, light and thermal emission, LT/A, TT/A SQUID, and MP. Of these, SQUID and MP techniques were pursued for further analysis. Also magnetoresistive current imaging technology is discussed and compared to SQUID.

  8. Comparative analysis of data quality and applications in vegetation of HJ-1A CCD images

    NASA Astrophysics Data System (ADS)

    Wei, Hongwei; Tian, Qingjiu; Huang, Yan; Wang, Yan

    2014-05-01

    To study the data quality and to find the differences in vegetation monitoring applications, the same region at Chuzhou Lai 'an, the data of HJ-1A CCD1 on the April 1st, 2012 and the data of HJ-1A CCD2 on the March 31, 2012 have being comparative analysis by the method of objective quality (image)assessment which selecting over five spectral image evaluation parameters: radiation precision (mean, variance, inclination, steepness), information entropy, signal-to-noise ratio, sharpness, contrast, and normalized differential vegetation index. The results show that there is little differences between the HJ-1A CCD1 and CCD2 by objective evaluation of data quality except radiation precision conform to their design theory, so the conclusion is that the difference of them without considering on the usual unless continuation;and Combination of field observation data Lai'an spectral data and GPS data (each point),selecting the normalized difference vegetation index as CCD1, CCD2 in vegetation monitoring application on the evaluation of the differences, and the specific process is based on GPS data is divided into nine small plots of spectral data ,and image data of nine one-to-one correspondence plots, and their normalized difference vegetation index values were calculated ,and measured spectra data resampling HJ-1A CCD1, CCD2 spectral response function calculated NDVI, and the results show that there is little differences between the HJ-1A CCD1 and CCD2 by objective evaluation of data quality, and, the differences of wheat `s reflection and normalized vegetation index is mainly due to calibration coefficients of CCD1 and CCD2, the differences of the solar elevation angle when obtaining the image and atmospheric conditions, so it has to consider the performance indicators as well as access conditions of CCD1 and CCD2, and to be take the normalization techniques for processing for the comparison analysis in the use of HJ-1A CCD Data to surface dynamic changes; Finally, in

  9. Development of filter exchangeable 3CCD camera for multispectral imaging acquisition

    NASA Astrophysics Data System (ADS)

    Lee, Hoyoung; Park, Soo Hyun; Kim, Moon S.; Noh, Sang Ha

    2012-05-01

    There are a lot of methods to acquire multispectral images. Dynamic band selective and area-scan multispectral camera has not developed yet. This research focused on development of a filter exchangeable 3CCD camera which is modified from the conventional 3CCD camera. The camera consists of F-mounted lens, image splitter without dichroic coating, three bandpass filters, three image sensors, filer exchangeable frame and electric circuit for parallel image signal processing. In addition firmware and application software have developed. Remarkable improvements compared to a conventional 3CCD camera are its redesigned image splitter and filter exchangeable frame. Computer simulation is required to visualize a pathway of ray inside of prism when redesigning image splitter. Then the dimensions of splitter are determined by computer simulation which has options of BK7 glass and non-dichroic coating. These properties have been considered to obtain full wavelength rays on all film planes. The image splitter is verified by two line lasers with narrow waveband. The filter exchangeable frame is designed to make swap bandpass filters without displacement change of image sensors on film plane. The developed 3CCD camera is evaluated to application of detection to scab and bruise on Fuji apple. As a result, filter exchangeable 3CCD camera could give meaningful functionality for various multispectral applications which need to exchange bandpass filter.

  10. The research and development of CCD-based slab continuous casting mold copper surface imaging system

    NASA Astrophysics Data System (ADS)

    Wang, Xingdong; Zhang, Liugang; Xie, Haihua; Long, Liaosha; Yu, Wenyong

    2011-11-01

    An imaging system for the continuous casting mold copper surface is researched and developed, to replace the on-line manual measuring method, which is used to checking Copper defects such as wearing, scratches and coating loss and other phenomena. Method: The imaging system proposes a special optical loop formed by three Mirrors, selects light source, CCD camera and lens type, designs mechanical transmission system and installation platform. Result: the optical loop and light source can insure imaging large-format object in narrow space. The CCD camera and lens determine the accuracy of horizontal scanning, and the mechanical transmission system ensures accuracy of the vertical scan. The installation platform supplies base and platform for the system. Conclusions: CCD-based copper surface imaging system effectively prevent defects such as missed measuring and low efficiency, etc. It can automatically and accurately shoot copper surface images on-line, and supply basis for image processing, defects identification and copper changing in the late.

  11. Evaluation of image quality of a new CCD-based system for chest imaging

    NASA Astrophysics Data System (ADS)

    Sund, Patrik; Kheddache, Susanne; Mansson, Lars G.; Bath, Magnus; Tylen, Ulf

    2000-04-01

    The Imix radiography system (Qy Imix Ab, Finland)consists of an intensifying screen, optics, and a CCD camera. An upgrade of this system (Imix 2000) with a red-emitting screen and new optics has recently been released. The image quality of Imix (original version), Imix 200, and two storage-phosphor systems, Fuji FCR 9501 and Agfa ADC70 was evaluated in physical terms (DQE) and with visual grading of the visibility of anatomical structures in clinical images (141 kV). PA chest images of 50 healthy volunteers were evaluated by experienced radiologists. All images were evaluated on Siemens Simomed monitors, using the European Quality Criteria. The maximum DQE values for Imix, Imix 2000, Agfa and Fuji were 11%, 14%, 17% and 19%, respectively (141kV, 5μGy). Using the visual grading, the observers rated the systems in the following descending order. Fuji, Imix 2000, Agfa, and Imix. Thus, the upgrade to Imix 2000 resulted in higher DQE values and a significant improvement in clinical image quality. The visual grading agrees reasonably well with the DQE results; however, Imix 2000 received a better score than what could be expected from the DQE measurements. Keywords: CCD Technique, Chest Imaging, Digital Radiography, DQE, Image Quality, Visual Grading Analysis

  12. A new segmentation algorithm for lunar surface terrain based on CCD images

    NASA Astrophysics Data System (ADS)

    Jiang, Hong-Kun; Tian, Xiao-Lin; Xu, Ao-Ao

    2015-09-01

    Terrain classification is one of the critical steps used in lunar geomorphologic analysis and landing site selection. Most of the published works have focused on a Digital Elevation Model (DEM) to distinguish different regions of lunar terrain. This paper presents an algorithm that can be applied to lunar CCD images by blocking and clustering according to image features, which can accurately distinguish between lunar highland and lunar mare. The new algorithm, compared with the traditional algorithm, can improve classification accuracy. The new algorithm incorporates two new features and one Tamura texture feature. The new features are generating an enhanced image histogram and modeling the properties of light reflection, which can represent the geological characteristics based on CCD gray level images. These features are applied to identify texture in order to perform image clustering and segmentation by a weighted Euclidean distance to distinguish between lunar mare and lunar highlands. The new algorithm has been tested on Chang'e-1 CCD data and the testing result has been compared with geological data published by the U.S. Geological Survey. The result has shown that the algorithm can effectively distinguish the lunar mare from highlands in CCD images. The overall accuracy of the proposed algorithm is satisfactory, and the Kappa coefficient is 0.802, which is higher than the result of combining the DEM with CCD images.

  13. The future scientific CCD

    NASA Technical Reports Server (NTRS)

    Janesick, J. R.; Elliott, T.; Collins, S.; Marsh, H.; Blouke, M. M.

    1984-01-01

    Since the first introduction of charge-coupled devices (CCDs) in 1970, CCDs have been considered for applications related to memories, logic circuits, and the detection of visible radiation. It is pointed out, however, that the mass market orientation of CCD development has left largely untapped the enormous potential of these devices for advanced scientific instrumentation. The present paper has, therefore, the objective to introduce the CCD characteristics to the scientific community, taking into account prospects for further improvement. Attention is given to evaluation criteria, a summary of current CCDs, CCD performance characteristics, absolute calibration tools, quantum efficiency, aspects of charge collection, charge transfer efficiency, read noise, and predictions regarding the characteristics of the next generation of silicon scientific CCD imagers.

  14. Space station application of CCD image sensors for x-ray imaging

    SciTech Connect

    Lowrance, John L.

    1997-01-10

    Charge Coupled Device (CCD) type solid state image sensors are employed in a number of space based imaging experiments and will be the basis for a camera system to acquire x-ray diffraction images on board the Space Station. This paper will present the system engineering considerations that led to the selection of CCDs over other x-ray imaging technologies and the design of the camera system. This will include discussion of the special requirements imposed by the space environment and this x-ray crystallography mission. This systems engineering discussion will be followed by a summary of high spatial resolution CCDs that are candidates for this camera, what may become available in the future, and what improvements would make CCDs even more suited to such X-ray imaging applications on the ground as well as in space.

  15. High-accuracy x-ray imaging: screen, lens, and CCD

    NASA Astrophysics Data System (ADS)

    Zeman, Herbert D.; DiBianca, Frank A.; Thomason, Donald B.; Sebes, Jeno I.; Lovhoiden, Gunnar; Liao, D.-Z.; Kambeyanda, Dona

    1993-09-01

    A liquid nitrogen cooled CCD TV camera from Astromed, Ltd. has been used for quantitative X-ray medical imaging. The CCD camera is coupled to a Kodak Lanex Regular X-ray intensifying screen with a 5:1 macro lens for bone mineral densitometry of the femur of a rat for a study of the development of osteoporosis. As a feasibility study of the use of the CCD for mammography, a 2:1 macro lens has been used to couple the CCD to a clear CsI(Tl) crystal, 100 mm in diameter and 3 mm thick. The spatial resolution and quantum efficiency of the system is significantly improved by replacing the Lanex Regular screen with the CsI(Tl) crystal.

  16. LED characterization for development of on-board calibration unit of CCD-based advanced wide-field sensor camera of Resourcesat-2A

    NASA Astrophysics Data System (ADS)

    Chatterjee, Abhijit; Verma, Anurag

    2016-05-01

    The Advanced Wide Field Sensor (AWiFS) camera caters to high temporal resolution requirement of Resourcesat-2A mission with repeativity of 5 days. The AWiFS camera consists of four spectral bands, three in the visible and near IR and one in the short wave infrared. The imaging concept in VNIR bands is based on push broom scanning that uses linear array silicon charge coupled device (CCD) based Focal Plane Array (FPA). On-Board Calibration unit for these CCD based FPAs is used to monitor any degradation in FPA during entire mission life. Four LEDs are operated in constant current mode and 16 different light intensity levels are generated by electronically changing exposure of CCD throughout the calibration cycle. This paper describes experimental setup and characterization results of various flight model visible LEDs (λP=650nm) for development of On-Board Calibration unit of Advanced Wide Field Sensor (AWiFS) camera of RESOURCESAT-2A. Various LED configurations have been studied to meet dynamic range coverage of 6000 pixels silicon CCD based focal plane array from 20% to 60% of saturation during night pass of the satellite to identify degradation of detector elements. The paper also explains comparison of simulation and experimental results of CCD output profile at different LED combinations in constant current mode.

  17. Method for implementation of back-illuminated CMOS or CCD imagers

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor)

    2008-01-01

    A method for implementation of back-illuminated CMOS or CCD imagers. An oxide layer buried between silicon wafer and device silicon is provided. The oxide layer forms a passivation layer in the imaging structure. A device layer and interlayer dielectric are formed, and the silicon wafer is removed to expose the oxide layer.

  18. Technology advancement of the CCD201-20 EMCCD for the WFIRST coronagraph instrument: sensor characterization and radiation damage

    NASA Astrophysics Data System (ADS)

    Harding, Leon K.; Demers, Richard T.; Hoenk, Michael; Peddada, Pavani; Nemati, Bijan; Cherng, Michael; Michaels, Darren; Neat, Leo S.; Loc, Anthony; Bush, Nathan; Hall, David; Murray, Neil; Gow, Jason; Burgon, Ross; Holland, Andrew; Reinheimer, Alice; Jorden, Paul R.; Jordan, Douglas

    2016-01-01

    The Wide Field InfraRed Survey Telescope-Astrophysics Focused Telescope Asset (WFIRST-AFTA) mission is a 2.4-m class space telescope that will be used across a swath of astrophysical research domains. JPL will provide a high-contrast imaging coronagraph instrument-one of two major astronomical instruments. In order to achieve the low noise performance required to detect planets under extremely low flux conditions, the electron multiplying charge-coupled device (EMCCD) has been baselined for both of the coronagraph's sensors-the imaging camera and integral field spectrograph. JPL has established an EMCCD test laboratory in order to advance EMCCD maturity to technology readiness level-6. This plan incorporates full sensor characterization, including read noise, dark current, and clock-induced charge. In addition, by considering the unique challenges of the WFIRST space environment, degradation to the sensor's charge transfer efficiency will be assessed, as a result of damage from high-energy particles such as protons, electrons, and cosmic rays. Science-grade CCD201-20 EMCCDs have been irradiated to a proton fluence that reflects the projected WFIRST orbit. Performance degradation due to radiation displacement damage is reported, which is the first such study for a CCD201-20 that replicates the WFIRST conditions. In addition, techniques intended to identify and mitigate radiation-induced electron trapping, such as trap pumping, custom clocking, and thermal cycling, are discussed.

  19. CCD imaging technology and the war on crime

    NASA Astrophysics Data System (ADS)

    McNeill, Glenn E.

    1992-08-01

    Linear array based CCD technology has been successfully used in the development of an Automatic Currency Reader/Comparator (ACR/C) system. The ACR/C system is designed to provide a method for tracking US currency in the organized crime and drug trafficking environments where large amounts of cash are involved in illegal transactions and money laundering activities. United States currency notes can be uniquely identified by the combination of the denomination serial number and series year. The ACR/C system processes notes at five notes per second using a custom transport a stationary linear array and optical character recognition (OCR) techniques to make such identifications. In this way large sums of money can be " marked" (using the system to read and store their identifiers) and then circulated within various crime networks. The system can later be used to read and compare confiscated notes to the known sets of identifiers from the " marked" set to document a trail of criminal activities. With the ACR/C law enforcement agencies can efficiently identify currency without actually marking it. This provides an undetectable means for making each note individually traceable and facilitates record keeping for providing evidence in a court of law. In addition when multiple systems are used in conjunction with a central data base the system can be used to track currency geographically. 1.

  20. Development of a Portable 3CCD Camera System for Multispectral Imaging of Biological Samples

    PubMed Central

    Lee, Hoyoung; Park, Soo Hyun; Noh, Sang Ha; Lim, Jongguk; Kim, Moon S.

    2014-01-01

    Recent studies have suggested the need for imaging devices capable of multispectral imaging beyond the visible region, to allow for quality and safety evaluations of agricultural commodities. Conventional multispectral imaging devices lack flexibility in spectral waveband selectivity for such applications. In this paper, a recently developed portable 3CCD camera with significant improvements over existing imaging devices is presented. A beam-splitter prism assembly for 3CCD was designed to accommodate three interference filters that can be easily changed for application-specific multispectral waveband selection in the 400 to 1000 nm region. We also designed and integrated electronic components on printed circuit boards with firmware programming, enabling parallel processing, synchronization, and independent control of the three CCD sensors, to ensure the transfer of data without significant delay or data loss due to buffering. The system can stream 30 frames (3-waveband images in each frame) per second. The potential utility of the 3CCD camera system was demonstrated in the laboratory for detecting defect spots on apples. PMID:25350510

  1. Development of a portable 3CCD camera system for multispectral imaging of biological samples.

    PubMed

    Lee, Hoyoung; Park, Soo Hyun; Noh, Sang Ha; Lim, Jongguk; Kim, Moon S

    2014-01-01

    Recent studies have suggested the need for imaging devices capable of multispectral imaging beyond the visible region, to allow for quality and safety evaluations of agricultural commodities. Conventional multispectral imaging devices lack flexibility in spectral waveband selectivity for such applications. In this paper, a recently developed portable 3CCD camera with significant improvements over existing imaging devices is presented. A beam-splitter prism assembly for 3CCD was designed to accommodate three interference filters that can be easily changed for application-specific multispectral waveband selection in the 400 to 1000 nm region. We also designed and integrated electronic components on printed circuit boards with firmware programming, enabling parallel processing, synchronization, and independent control of the three CCD sensors, to ensure the transfer of data without significant delay or data loss due to buffering. The system can stream 30 frames (3-waveband images in each frame) per second. The potential utility of the 3CCD camera system was demonstrated in the laboratory for detecting defect spots on apples. PMID:25350510

  2. Electron detection characteristics of a slow-scan CCD camera, imaging plates and film, and electron image restoration.

    PubMed

    Zuo, J M

    2000-05-01

    Electron detection characteristics are summarized for the slow scan CCD (SSC) camera, imaging plates, and film. The advantage of each detector is demonstrated with the selected examples of electron diffraction and imaging. The Richardson-Lucy algorithm for image restoration is described and tested for images recorded with the SSC camera. The effectiveness of image restoration is demonstrated for the recorded high-resolution lattice image, energy-loss spectrum, and convergent beam electron diffraction (CBED) pattern. PMID:10816266

  3. CCD imaging of the inner coma jets of comet P/Halley

    NASA Technical Reports Server (NTRS)

    Boswell, James; Hughes, David W.

    1992-01-01

    We analyze the inner coma section of a CCD image of comet P/Halley taken at 1807 UT on 13 March 1986 using a C2 filter (wavelength 5000 to 5200A, half maximum) with the 3.8 m Anglo Australian Telescope at Siding Springs, Australia. Atmospheric turbulence leads to a spreading of the image detail and this produces a blander image of the inner coma region with a slower radial decrease of brightness in comparison to the unaffected image. We remove this smearing by utilizing the point spread function of a star on the same CCD image. Jets were then revealed by removing the average background. Analysis of the jet structure enabled us to estimate the lower limit of the parent molecule velocity. This is found to be 0.3 km s(exp -1).

  4. The interface of CCD image line sensor ILX511 in technical spectrometer

    NASA Astrophysics Data System (ADS)

    BartonÄk, LudÄk.; Keprt, Jiri, Sr.

    2003-11-01

    This paper presents a way for practical use of the CCD linear image sensor for scanning of light in some optical applications (spectroscopy). Communication of the equipment (detector CCD) with computer is realized by the help of a parallel interface of a personal computer (PC) without additive interface card. In final part of this contribution is presented a realization of measuring circuit (enhanced parallel interface PC) for the sensor ILXS 1 1. The use of the line detector is demonstrated on detection of the optical spectrum of the mercury lamp.

  5. A configurable distributed high-performance computing framework for satellite's TDI-CCD imaging simulation

    NASA Astrophysics Data System (ADS)

    Xue, Bo; Mao, Bingjing; Chen, Xiaomei; Ni, Guoqiang

    2010-11-01

    This paper renders a configurable distributed high performance computing(HPC) framework for TDI-CCD imaging simulation. It uses strategy pattern to adapt multi-algorithms. Thus, this framework help to decrease the simulation time with low expense. Imaging simulation for TDI-CCD mounted on satellite contains four processes: 1) atmosphere leads degradation, 2) optical system leads degradation, 3) electronic system of TDI-CCD leads degradation and re-sampling process, 4) data integration. Process 1) to 3) utilize diversity data-intensity algorithms such as FFT, convolution and LaGrange Interpol etc., which requires powerful CPU. Even uses Intel Xeon X5550 processor, regular series process method takes more than 30 hours for a simulation whose result image size is 1500 * 1462. With literature study, there isn't any mature distributing HPC framework in this field. Here we developed a distribute computing framework for TDI-CCD imaging simulation, which is based on WCF[1], uses Client/Server (C/S) layer and invokes the free CPU resources in LAN. The server pushes the process 1) to 3) tasks to those free computing capacity. Ultimately we rendered the HPC in low cost. In the computing experiment with 4 symmetric nodes and 1 server , this framework reduced about 74% simulation time. Adding more asymmetric nodes to the computing network, the time decreased namely. In conclusion, this framework could provide unlimited computation capacity in condition that the network and task management server are affordable. And this is the brand new HPC solution for TDI-CCD imaging simulation and similar applications.

  6. Novel driver method to improve ordinary CCD frame rate for high-speed imaging diagnosis

    NASA Astrophysics Data System (ADS)

    Luo, Tong-Ding; Li, Bin-Kang; Yang, Shao-Hua; Guo, Ming-An; Yan, Ming

    2016-06-01

    The use of ordinary Charge-coupled-Device (CCD) imagers for the analysis of fast physical phenomenon is restricted because of the low-speed performance resulting from their long output times. Even though the form of Intensified-CCD (ICCD), coupled with a gated image intensifier, has extended their use for high speed imaging, the deficiency remains to be solved that ICDD could record only one image in a single shot. This paper presents a novel driver method designed to significantly improve the ordinary interline CCD burst frame rate for high-speed photography. This method is based on the use of vertical registers as storage, so that a small number of additional frames comprised of reduced-spatial-resolution images obtained via a specific sampling operation can be buffered. Hence, the interval time of the received series of images is related to the exposure and vertical transfer times only and, thus, the burst frame rate can be increased significantly. A prototype camera based on this method is designed as part of this study, exhibiting a burst rate of up to 250,000 frames per second (fps) and a capacity to record three continuous images. This device exhibits a speed enhancement of approximately 16,000 times compared with the conventional speed, with a spatial resolution reduction of only 1/4.

  7. Design and realization of an image mosaic system on the CCD aerial camera

    NASA Astrophysics Data System (ADS)

    Liu, Hai ying; Wang, Peng; Zhu, Hai bin; Li, Yan; Zhang, Shao jun

    2015-08-01

    It has long been difficulties in aerial photograph to stitch multi-route images into a panoramic image in real time for multi-route flight framing CCD camera with very large amount of data, and high accuracy requirements. An automatic aerial image mosaic system based on GPU development platform is described in this paper. Parallel computing of SIFT feature extraction and matching algorithm module is achieved by using CUDA technology for motion model parameter estimation on the platform, which makes it's possible to stitch multiple CCD images in real-time. Aerial tests proved that the mosaic system meets the user's requirements with 99% accuracy and 30 to 50 times' speed improvement of the normal mosaic system.

  8. Fundamental performance differences between CMOS and CCD imagers: Part II

    NASA Astrophysics Data System (ADS)

    Janesick, James; Andrews, James; Tower, John; Grygon, Mark; Elliott, Tom; Cheng, John; Lesser, Michael; Pinter, Jeff

    2007-09-01

    A new class of CMOS imagers that compete with scientific CCDs is presented. The sensors are based on deep depletion backside illuminated technology to achieve high near infrared quantum efficiency and low pixel cross-talk. The imagers deliver very low read noise suitable for single photon counting - Fano-noise limited soft x-ray applications. Digital correlated double sampling signal processing necessary to achieve low read noise performance is analyzed and demonstrated for CMOS use. Detailed experimental data products generated by different pixel architectures (notably 3TPPD, 5TPPD and 6TPG designs) are presented including read noise, charge capacity, dynamic range, quantum efficiency, charge collection and transfer efficiency and dark current generation. Radiation damage data taken for the imagers is also reported.

  9. A pnCCD-based, fast direct single electron imaging camera for TEM and STEM

    NASA Astrophysics Data System (ADS)

    Ryll, H.; Simson, M.; Hartmann, R.; Holl, P.; Huth, M.; Ihle, S.; Kondo, Y.; Kotula, P.; Liebel, A.; Müller-Caspary, K.; Rosenauer, A.; Sagawa, R.; Schmidt, J.; Soltau, H.; Strüder, L.

    2016-04-01

    We report on a new camera that is based on a pnCCD sensor for applications in scanning transmission electron microscopy. Emerging new microscopy techniques demand improved detectors with regards to readout rate, sensitivity and radiation hardness, especially in scanning mode. The pnCCD is a 2D imaging sensor that meets these requirements. Its intrinsic radiation hardness permits direct detection of electrons. The pnCCD is read out at a rate of 1,150 frames per second with an image area of 264 x 264 pixel. In binning or windowing modes, the readout rate is increased almost linearly, for example to 4000 frames per second at 4× binning (264 x 66 pixel). Single electrons with energies from 300 keV down to 5 keV can be distinguished due to the high sensitivity of the detector. Three applications in scanning transmission electron microscopy are highlighted to demonstrate that the pnCCD satisfies experimental requirements, especially fast recording of 2D images. In the first application, 65536 2D diffraction patterns were recorded in 70 s. STEM images corresponding to intensities of various diffraction peaks were reconstructed. For the second application, the microscope was operated in a Lorentz-like mode. Magnetic domains were imaged in an area of 256 x 256 sample points in less than 37 seconds for a total of 65536 images each with 264 x 132 pixels. Due to information provided by the two-dimensional images, not only the amplitude but also the direction of the magnetic field could be determined. In the third application, millisecond images of a semiconductor nanostructure were recorded to determine the lattice strain in the sample. A speed-up in measurement time by a factor of 200 could be achieved compared to a previously used camera system.

  10. Structure for implementation of back-illuminated CMOS or CCD imagers

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Cunningham, Thomas J. (Inventor)

    2009-01-01

    A structure for implementation of back-illuminated CMOS or CCD imagers. An epitaxial silicon layer is connected with a passivation layer, acting as a junction anode. The epitaxial silicon layer converts light passing through the passivation layer and collected by the imaging structure to photoelectrons. A semiconductor well is also provided, located opposite the passivation layer with respect to the epitaxial silicon layer, acting as a junction cathode. Prior to detection, light does not pass through a dielectric separating interconnection metal layers.

  11. Astrometric Performance of STIS CCD CTI Corrections on Omega Cen Images

    NASA Astrophysics Data System (ADS)

    Biretta, John; Lockwood, Sean; Debes, John

    2015-09-01

    Here we examine the astrometric performance of these new pixel-based CTI corrections, and compare their performance to the already existing empirical CTI corrections. Tests are performed using imaging observations of the star cluster Omega Cen taken in 2012. The astrometric effects of CTI are evaluated by comparing the Y coordinates of the stars on images read out through the A and D amplifiers, which are located at opposite corners of the CCD detector.

  12. [An Improved DDV Method to Retrieve AOT for HJ CCD Image in Typical Mountainous Areas].

    PubMed

    Zhao, Zhi-qiang; Li, Ai-nong; Bian, Jin-hu; Huang, Cheng-quan

    2015-06-01

    Domestic HJ CCD imaging applications in environment and disaster monitoring and prediction has great potential. But, HJ CCD image lack of Mid-Nir band can not directly retrieve Aerosol Optical Thickness (AOT) by the traditional Dark Dense Vegetation (DDV) method, and the mountain AOT changes in space-time dramatically affected by the mountain environment, which reduces the accuracy of atmospheric correction. Based on wide distribution of mountainous dark dense forest, the red band histogram threshold method was introduced to identify the mountainous DDV pixels. Subsequently, the AOT of DDV pixels were retrieved by lookup table constructed by 6S radiative transfer model with assumption of constant ratio between surface reflectance in red and blue bands, and then were interpolated to whole image. MODIS aerosol product and the retrieved AOT by the proposed algorithm had very good consistency in spatial distribution, and HJ CCD image was more suitable for the remote sensing monitoring of aerosol in mountain areas, which had higher spatial resolution. Their fitting curve of scatterplot was y = 0.828 6x-0.01 and R2 was 0.984 3 respectively. Which indicate the improved DDV method can effectively retrieve AOT, and its precision can satisfy the atmospheric correction and terrain radiation correction for Hj CCD image in mountainous areas. The improvement of traditional DDV method can effectively solve the insufficient information problem of the HJ CCD image which have only visible light and near infrared band, when solving radiative transfer equation. Meanwhile, the improved method fully considered the influence of mountainous terrain environment. It lays a solid foundation for the HJ CCD image atmospheric correction in the mountainous areas, and offers the possibility for its automated processing. In addition, the red band histogram threshold method was better than NDVI method to identify mountain DDV pixels. And, the lookup table and ratio between surface reflectance

  13. Online measuring method of the wheel set wear based on CCD and image processing

    NASA Astrophysics Data System (ADS)

    Wu, Kaihua; Zhang, Jianhua; Yan, Kuang

    2005-01-01

    The online measurement of wheel set wear parameters is important for ensuring the safety of train vehicle and increasing the reliability and efficiency of maintaining. The paper researched an automatic measuring method of wheel set parameters based on CCD and image processing. The method used precision laser displacement sensor, CCD, digital image processing and motion control technology to realize the non-contact automatic measuring of wheel set parameters. These parameters include the flange thickness, flange height, wheel diameter, rim inside distance, rim inside thickness, rim width, scotching and flaking on wheel tread. The tread and flange profile were captured using laser source and high resolution CCD sensor. The image SNR was gained through narrow band-pass optical filters which wavelength matched with laser source. In order to detect the irregular tread failures formed in running of train vehicle, the paper used precision laser displacement sensor to scan the tread and acquire the position while the wheel set was rotating. The displacement data of different positions were transformed to digital image. Then digital image processing was used to distinguish and judge the failures. The measuring accuracy of geometrical parameters, scotching depth and flaking length were 0.2mm, 0.1mm and 0.5mm respectively. The repeatability and accuracy can meet the demand of non-contact online wheel set maintaining.

  14. Design and performance of charge multiplying color FIT CCD image sensor

    NASA Astrophysics Data System (ADS)

    Kobayashi, Izumi; Shibuya, Hiroaki; Tachibana, Toshio; Nishiwaki, Takahiro; Kashima, Shunji; Hynecek, Jaroslav

    2005-03-01

    The paper describes important design features and resulting performance of a color VGA format Frame Interline Transfer CCD image sensor that utilizes Charge Carrier Multiplication for increased sensitivity and low noise. The description includes the details of the photo site design that is formed by a pinned photodiode with a lateral anti-blooming drain. The design details of the photo-site transfer gate region are also given together with the design details of the vertical CCD register that result in a fast charge transfer into the memory and thus low smear. Since the device is not using the vertical overflow anti-blooming drain for the booming control, the near IR performance is not reduced. The color sensing capability is achieved by employing either RGB or complementary color filters. The remaining focus of the article is on the typical characterization results such as the CTE, image lag, and low dark current. The NIR and color imaging performance at low light levels is investigated in detail and characterized. In conclusion several typical scene color images taken by the camera that uses the developed charge-multiplying FIT CCD image sensor are shown.

  15. Dynamic monitoring of lake based on HJ-CCD Images: a case study of Poyang Lake

    NASA Astrophysics Data System (ADS)

    Liu, Dong; Huang, Haiqing; Gong, Fang; Zhu, Qiankun; Yang, Xuefei

    2014-11-01

    Lake ecological environment is changing, driving by natural and human factors, and in turn influence people's living and producing. Therefore, dynamic monitoring of lake based on remote sensing technologies will play an important role to the disaster prevention and reduction work of lakes. In this paper, we expounded a series of work to realized monitor Poyang Lake dynamically by using HJ-CCD images. First, we did pretreatment to all HJ-CCD images, which mainly contain geometric correction, atmospheric correlation, image clipping, etc. Then, based on different features between water and non-water in different index layers, we extracted the covered area by water in different times from the corresponding HJ-CCD images, and we also extracted the true area through visual interpretation method. After that, by combining the water boundaries and DEM, we also estimated water level and water capacity in different times. Results of our work showed that the mean absolute error of water area extracted through remote technologies is 5.57%. The relationship of remote sensing areas and visual interpretation areas could be described as Strue = 0.8757*Sinterp + 110.24, with R2 = 0.9807. Besides, there was obvious relationship between water area and water capacity of Poyang Lake too, and the relations can be described with linear function. Based on such results, we can realize the dynamic estimation of Poyang Lake's area and capacity from daily gotten HJ-CCD image which covers the District of Poyang Lake. In other words, the results of this paper can provide decision basis for Poyang Lake's real-time, dynamic, economic monitoring.

  16. High-resolution image digitizing through 12x3-bit RGB-filtered CCD camera

    NASA Astrophysics Data System (ADS)

    Cheng, Andrew Y. S.; Pau, Michael C. Y.

    1996-09-01

    A high resolution computer-controlled CCD image capturing system is developed by using a 12 bits 1024 by 1024 pixels CCD camera and motorized RGB filters to grasp an image with color depth up to 36 bits. The filters distinguish the major components of color and collect them separately while the CCD camera maintains the spatial resolution and detector filling factor. The color separation can be done optically rather than electronically. The operation is simply by placing the capturing objects like color photos, slides and even x-ray transparencies under the camera system, the necessary parameters such as integration time, mixing level and light intensity are automatically adjusted by an on-line expert system. This greatly reduces the restrictions of the capturing species. This unique approach can save considerable time for adjusting the quality of image, give much more flexibility of manipulating captured object even if it is a 3D object with minimal setup fixers. In addition, cross sectional dimension of a 3D capturing object can be analyzed by adapting a fiber optic ring light source. It is particularly useful in non-contact metrology of a 3D structure. The digitized information can be stored in an easily transferable format. Users can also perform a special LUT mapping automatically or manually. Applications of the system include medical images archiving, printing quality control, 3D machine vision, and etc.

  17. Star-field identification algorithm. [for implementation on CCD-based imaging camera

    NASA Technical Reports Server (NTRS)

    Scholl, M. S.

    1993-01-01

    A description of a new star-field identification algorithm that is suitable for implementation on CCD-based imaging cameras is presented. The minimum identifiable star pattern element consists of an oriented star triplet defined by three stars, their celestial coordinates, and their visual magnitudes. The algorithm incorporates tolerance to faulty input data, errors in the reference catalog, and instrument-induced systematic errors.

  18. Design of multi-mode compatible image acquisition system for HD area array CCD

    NASA Astrophysics Data System (ADS)

    Wang, Chen; Sui, Xiubao

    2014-11-01

    Combining with the current development trend in video surveillance-digitization and high-definition, a multimode-compatible image acquisition system for HD area array CCD is designed. The hardware and software designs of the color video capture system of HD area array CCD KAI-02150 presented by Truesense Imaging company are analyzed, and the structure parameters of the HD area array CCD and the color video gathering principle of the acquisition system are introduced. Then, the CCD control sequence and the timing logic of the whole capture system are realized. The noises of the video signal (KTC noise and 1/f noise) are filtered by using the Correlated Double Sampling (CDS) technique to enhance the signal-to-noise ratio of the system. The compatible designs in both software and hardware for the two other image sensors of the same series: KAI-04050 and KAI-08050 are put forward; the effective pixels of these two HD image sensors are respectively as many as four million and eight million. A Field Programmable Gate Array (FPGA) is adopted as the key controller of the system to perform the modularization design from top to bottom, which realizes the hardware design by software and improves development efficiency. At last, the required time sequence driving is simulated accurately by the use of development platform of Quartus II 12.1 combining with VHDL. The result of the simulation indicates that the driving circuit is characterized by simple framework, low power consumption, and strong anti-interference ability, which meet the demand of miniaturization and high-definition for the current tendency.

  19. CCD Camera

    DOEpatents

    Roth, Roger R.

    1983-01-01

    A CCD camera capable of observing a moving object which has varying intensities of radiation eminating therefrom and which may move at varying speeds is shown wherein there is substantially no overlapping of successive images and wherein the exposure times and scan times may be varied independently of each other.

  20. CCD Camera

    DOEpatents

    Roth, R.R.

    1983-08-02

    A CCD camera capable of observing a moving object which has varying intensities of radiation emanating therefrom and which may move at varying speeds is shown wherein there is substantially no overlapping of successive images and wherein the exposure times and scan times may be varied independently of each other. 7 figs.

  1. Optimised Post-Exposure Image Sharpening Code for L3-CCD Detectors

    SciTech Connect

    Harding, Leon K.; Butler, Raymond F.; Redfern, R. Michael; Sheehan, Brendan J.; McDonald, James

    2008-02-22

    As light from celestial bodies traverses Earth's atmosphere, the wavefronts are distorted by atmospheric turbulence, thereby lowering the angular resolution of ground-based imaging. Rapid time-series imaging enables Post-Exposure Image Sharpening (PEIS) techniques, which employ shift-and-add frame registration to remove the tip-tilt component of the wavefront error--as well as telescope wobble, thus benefiting all observations. Further resolution gains are possible by selecting only frames with the best instantaneous seeing--a technique sometimes calling 'Lucky Imaging'. We implemented these techniques in the 1990s, with the TRIFFID imaging photon-counting camera, and its associated data reduction software. The software was originally written for time-tagged photon-list data formats, recorded by detectors such as the MAMA. This paper describes our deep re-structuring of the software to handle the 2-d FITS images produced by Low Light Level CCD (L3-CCD) cameras, which have sufficient time-series resolution (>30 Hz) for PEIS. As before, our code can perform straight frame co-addition, use composite reference stars, perform PEIS under several different algorithms to determine the tip/tilt shifts, store 'quality' and shift information for each frame, perform frame selection, and generate exposure-maps for photometric correction. In addition, new code modules apply all 'static' calibrations (bias subtraction, dark subtraction and flat-fielding) to the frames immediately prior to the other algorithms. A unique feature of our PEIS/Lucky Imaging code is the use of bidirectional wiener-filtering. Coupled with the far higher sensitivity of the L3-CCD over the previous TRIFFID detectors, much fainter reference stars and much narrower time windows can be used.

  2. High-speed video recording system using multiple CCD imagers and digital storage

    NASA Astrophysics Data System (ADS)

    Racca, Roberto G.; Clements, Reginald M.

    1995-05-01

    This paper describes a fully solid state high speed video recording system. Its principle of operation is based on the use of several independent CCD imagers and an array of liquid crystal light valves that control which imager receives the light from the subject. The imagers are exposed in rapid succession and are then read out sequentially at standard video rate into digital memory, generating a time-resolved sequence with as many frames as there are imagers. This design allows the use of inexpensive, consumer-grade camera modules and electronics. A microprocessor-based controller, designed to accept up to ten imagers, handles all phases of the recording: exposure timing, image digitization and storage, and sequential playback onto a standard video monitor. The system is capable of recording full screen black and white images with spatial resolution similar to that of standard television, at rates of about 10,000 images per second in pulsed illumination mode. We have designed and built two optical configurations for the imager multiplexing system. The first one involves permanently splitting the subject light into multiple channels and placing a liquid crystal shutter in front of each imager. A prototype with three CCD imagers and shutters based on this configuration has allowed successful three-image video recordings of phenomena such as the action of an air rifle pellet shattering a piece of glass, using a high-intensity pulsed light emitting diode as the light source. The second configuration is more light-efficient in that it routes the entire subject light to each individual imager in sequence by using the liquid crystal cells as selectable binary switches. Despite some operational limitations, this method offers a solution when the available light, if subdivided among all the imagers, would not allow a sufficiently short exposure time.

  3. Advanced radiographic imaging techniques.

    NASA Technical Reports Server (NTRS)

    Beal, J. B.; Brown, R. L.

    1973-01-01

    Examination of the nature and operational constraints of conventional X-radiographic and neutron imaging methods, providing a foundation for a discussion of advanced radiographic imaging systems. Two types of solid-state image amplifiers designed to image X rays are described. Operational theory, panel construction, and performance characteristics are discussed. A closed-circuit television system for imaging neutrons is then described and the system design, operational theory, and performance characteristics are outlined. Emphasis is placed on a description of the advantages of these imaging systems over conventional methods.

  4. An abuttable CCD imager for visible and X-ray focal plane arrays

    NASA Technical Reports Server (NTRS)

    Burke, Barry E.; Mountain, Robert W.; Harrison, David C.; Bautz, Marshall W.; Doty, John P.

    1991-01-01

    A frame-transfer silicon charge-coupled-device (CCD) imager has been developed that can be closely abutted to other imagers on three sides of the imaging array. It is intended for use in multichip arrays. The device has 420 x 420 pixels in the imaging and frame-store regions and is constructed using a three-phase triple-polysilicon process. Particular emphasis has been placed on achieving low-noise charge detection for low-light-level imaging in the visible and maximum energy resolution for X-ray spectroscopic applications. Noise levels of 6 electrons at 1-MHz and less than 3 electrons at 100-kHz data rates have been achieved. Imagers have been fabricated on 1000-Ohm-cm material to maximize quantum efficiency and minimize split events in the soft X-ray regime.

  5. The measurement of astronomical parallaxes with CCD imaging cameras on small telescopes

    SciTech Connect

    Ratcliff, S.J. ); Balonek, T.J. ); Marschall, L.A. ); DuPuy, D.L. ); Pennypacker, C.R. ); Verma, R. ); Alexov, A. ); Bonney, V. )

    1993-03-01

    Small telescopes equipped with charge-coupled device (CCD) imaging cameras are well suited to introductory laboratory exercises in positional astronomy (astrometry). An elegant example is the determination of the parallax of extraterrestrial objects, such as asteroids. For laboratory exercises suitable for introductory students, the astronomical hardware needs are relatively modest, and, under the best circumstances, the analysis requires little more than arithmetic and a microcomputer with image display capabilities. Results from the first such coordinated parallax observations of asteroids ever made are presented. In addition, procedures for several related experiments, involving single-site observations and/or parallaxes of earth-orbiting artificial satellites, are outlined.

  6. [Advance in imaging spectropolarimeter].

    PubMed

    Wang, Xin-quan; Xiangli, Bin; Huang, Min; Hu, Liang; Zhou, Jin-song; Jing, Juan-juan

    2011-07-01

    Imaging spectropolarimeter (ISP) is a type of novel photoelectric sensor which integrated the functions of imaging, spectrometry and polarimetry. In the present paper, the concept of the ISP is introduced, and the advances in ISP at home and abroad in recent years is reviewed. The principles of ISPs based on novel devices, such as acousto-optic tunable filter (AOTF) and liquid crystal tunable filter (LCTF), are illustrated. In addition, the principles of ISPs developed by adding polarized components to the dispersing-type imaging spectrometer, spatially modulated Fourier transform imaging spectrometer, and computer tomography imaging spectrometer are introduced. Moreover, the trends of ISP are discussed too. PMID:21942063

  7. A new method of CCD dark current correction via extracting the dark Information from scientific images

    NASA Astrophysics Data System (ADS)

    Ma, Bin; Shang, Zhaohui; Hu, Yi; Liu, Qiang; Wang, Lifan; Wei, Peng

    2014-07-01

    We have developed a new method to correct dark current at relatively high temperatures for Charge-Coupled Device (CCD) images when dark frames cannot be obtained on the telescope. For images taken with the Antarctic Survey Telescopes (AST3) in 2012, due to the low cooling efficiency, the median CCD temperature was -46°C, resulting in a high dark current level of about 3e-/pix/sec, even comparable to the sky brightness (10e-/pix/sec). If not corrected, the nonuniformity of the dark current could even overweight the photon noise of the sky background. However, dark frames could not be obtained during the observing season because the camera was operated in frame-transfer mode without a shutter, and the telescope was unattended in winter. Here we present an alternative, but simple and effective method to derive the dark current frame from the scientific images. Then we can scale this dark frame to the temperature at which the scientific images were taken, and apply the dark frame corrections to the scientific images. We have applied this method to the AST3 data, and demonstrated that it can reduce the noise to a level roughly as low as the photon noise of the sky brightness, solving the high noise problem and improving the photometric precision. This method will also be helpful for other projects that suffer from similar issues.

  8. CCD mosaic images of the supernova remnant 3C 400.2

    NASA Technical Reports Server (NTRS)

    Winkler, P. F.; Olinger, Todd M.; Westerbeke, Scott A.

    1993-01-01

    We have constructed CCD mosaic images of the old Galactic supernova remnant 3C 400.2 in lines of H-alpha + forbidden N II, forbidden S II, and forbidden O III, plus a continuum band. These are the first CCD images covering the full extent of this remnant, and they reveal significantly more nebulosity than the deepest photographic plates. Comparison with radio and X-ray images indicates dramatically different morphology in the three regimes. The optical images both in H-alpha + forbidden N II and in forbidden S II show an almost complete, irregular shell of emission, with a diameter of about 16 arcmin, little over half that of the radio shell, while the X-ray structure is a centrally peaked ellipsoid. Approximate values for optical line fluxes are obtained; we estimate L(H-alpha) about 3 x 10 exp 35 ergs/s, roughly three times the X-ray luminosity. We also report a previously uncataloged planetary nebula southwest of 3C 400.2.

  9. An Automatic Technique for Finding Faint Moving Objects in Wide Field CCD Images

    NASA Astrophysics Data System (ADS)

    Hainaut, O. R.; Meech, K. J.

    1996-09-01

    The traditional method used to find moving objects in astronomical images is to blink pairs or series of frames after registering them to align the background objects. While this technique is extremely efficient in terms of the low signal-to-noise ratio that the human sight can detect, it proved to be extremely time-, brain- and eyesight-consuming. The wide-field images provided by the large CCD mosaic recently built at IfA cover a field of view of 20 to 30' over 8192(2) pixels. Blinking such images is an enormous task, comparable to that of blinking large photographic plates. However, as the data are available digitally (each image occupying 260Mb of disk space), we are developing a set of computer codes to perform the moving object identification in sets of frames. This poster will describe the techniques we use in order to reach a detection efficiency as good as that of a human blinker; the main steps are to find all the objects in each frame (for which we rely on ``S-Extractor'' (Bertin & Arnouts (1996), A&ASS 117, 393), then identify all the background objects, and finally to search the non-background objects for sources moving in a coherent fashion. We will also describe the results of this method applied to actual data from the 8k CCD mosaic. {This work is being supported, in part, by NSF grant AST 92-21318.}

  10. Design of Frame-transferred Surface Array CCD Imaging System for Dark Objects

    NASA Astrophysics Data System (ADS)

    Zhang, Yu-heng; Yan, Yi-hua

    2016-01-01

    In order to realize the requirement of low-noise observations of dark objects in deep-space explorations, the design method for a simple and stable space camera imaging system is proposed in this paper. Based on the back-illuminated frame-transferred surface array CCD (CCD47-20AIMO) produced by the British E2V company, the circuitry design is given for the every part of the system. In which the applications of the correlated double-sampling analog-digital converter (AD) and the synchronous dynamic random access memory (SDRAM) can effectively suppress the correlated noise in the image signal. In addition, a drive control method favorable to the adjustment of exposure time is proposed, in the light-sensing stage it provides the exposure time with an independent and adjustable time delay to make the imaging system satisfy the requirement of long exposure time setting. The imaging system adopts the Cyclone III-series EP3C25Q240C8 field programable gate array produced by the Altera company as the kernel control device, and the drives are programmed in modules according to the function of the every device, in favor of transplantation. The simulative and experimental results indicate that the drive circuitry works normally, and that the system design can satisfy the preset requirement.

  11. Design for the correction system of the real time nonuniformity of large area-array CCD image

    NASA Astrophysics Data System (ADS)

    Wang, Yan; Li, Chunmei; Lei, Ning

    2012-10-01

    With the robust thriving of aviation cameras and remote sensing technology, the linear-array CCD (charge-coupled device) and area CCD have developed toward large area CCD, which has a broad coverage and avoids the difficulty in jointing small area CCDs in addition to improving time resolution. However, due to the high amount of pixels and channels of large area CCD, photo-response non-uniformity (PRNU) is severe. In this paper, a real time non-uniformity correction system is introduced for a sort of large area full frame transfer CCD. First, the correction algorithm is elaborated according to CCD's working principle. Secondly, due to the high number of pixels and correction coefficient, ordinary chip memory cannot meet the requirement. The combination of external flash memory and DDR described in the paper satisfies large capacity memory and rapid real time correction. The methods and measurement steps for obtaining correction factors are provided simultaneously. At the end, an imaging test is made. The non-uniformity of the image is reduced to 0.38 % from the pre-correction 2.96 %, achieving an obvious reduction of non-uniformity. The result shows that the real time non-uniformity correction system can meet the demands of large area-array CCD.

  12. Linear CCD attitude measurement system based on the identification of the auxiliary array CCD

    NASA Astrophysics Data System (ADS)

    Hu, Yinghui; Yuan, Feng; Li, Kai; Wang, Yan

    2015-10-01

    Object to the high precision flying target attitude measurement issues of a large space and large field of view, comparing existing measurement methods, the idea is proposed of using two array CCD to assist in identifying the three linear CCD with multi-cooperative target attitude measurement system, and to address the existing nonlinear system errors and calibration parameters and more problems with nine linear CCD spectroscopic test system of too complicated constraints among camera position caused by excessive. The mathematical model of binocular vision and three linear CCD test system are established, co-spot composition triangle utilize three red LED position light, three points' coordinates are given in advance by Cooperate Measuring Machine, the red LED in the composition of the three sides of a triangle adds three blue LED light points as an auxiliary, so that array CCD is easier to identify three red LED light points, and linear CCD camera is installed of a red filter to filter out the blue LED light points while reducing stray light. Using array CCD to measure the spot, identifying and calculating the spatial coordinates solutions of red LED light points, while utilizing linear CCD to measure three red LED spot for solving linear CCD test system, which can be drawn from 27 solution. Measured with array CCD coordinates auxiliary linear CCD has achieved spot identification, and has solved the difficult problems of multi-objective linear CCD identification. Unique combination of linear CCD imaging features, linear CCD special cylindrical lens system is developed using telecentric optical design, the energy center of the spot position in the depth range of convergence in the direction is perpendicular to the optical axis of the small changes ensuring highprecision image quality, and the entire test system improves spatial object attitude measurement speed and precision.

  13. Design and Fabrication of High-Efficiency CMOS/CCD Imagers

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata

    2007-01-01

    An architecture for back-illuminated complementary metal oxide/semiconductor (CMOS) and charge-coupled-device (CCD) ultraviolet/visible/near infrared- light image sensors, and a method of fabrication to implement the architecture, are undergoing development. The architecture and method are expected to enable realization of the full potential of back-illuminated CMOS/CCD imagers to perform with high efficiency, high sensitivity, excellent angular response, and in-pixel signal processing. The architecture and method are compatible with next-generation CMOS dielectric-forming and metallization techniques, and the process flow of the method is compatible with process flows typical of the manufacture of very-large-scale integrated (VLSI) circuits. The architecture and method overcome all obstacles that have hitherto prevented high-yield, low-cost fabrication of back-illuminated CMOS/CCD imagers by use of standard VLSI fabrication tools and techniques. It is not possible to discuss the obstacles in detail within the space available for this article. Briefly, the obstacles are posed by the problems of generating light-absorbing layers having desired uniform and accurate thicknesses, passivation of surfaces, forming structures for efficient collection of charge carriers, and wafer-scale thinning (in contradistinction to diescale thinning). A basic element of the present architecture and method - the element that, more than any other, makes it possible to overcome the obstacles - is the use of an alternative starting material: Instead of starting with a conventional bulk-CMOS wafer that consists of a p-doped epitaxial silicon layer grown on a heavily-p-doped silicon substrate, one starts with a special silicon-on-insulator (SOI) wafer that consists of a thermal oxide buried between a lightly p- or n-doped, thick silicon layer and a device silicon layer of appropriate thickness and doping. The thick silicon layer is used as a handle: that is, as a mechanical support for the

  14. Advanced Geosynchronous Imager

    NASA Technical Reports Server (NTRS)

    Chesters, Dennis

    1999-01-01

    For improved understanding of chaotic processes and the diurnal cycle, an advanced GOES imager must also have the multi-spectral spectral bands used by low earth orbit (LEO) imagers, with on-orbit calibration for all bands. A synergy between GEO and LEO radiometry would enable earth system scientists to fuse the remote sensing data from all the spaceborne platforms. These additional radiometric capabilities are designed to observe important physical processes that vary rapidly and unpredicably: smoke, fires, precipitation, ozone, volcanic ash, cloud phase and height, and surface temperature. We believe the technology now exists to develop an imaging system that can meet future weather reporting and earth system science needs. To meet this need, we propose a design for a comprehensive geosynchronous atmospheric imager. This imager is envisioned to fly on a GOES-N class spacecraft, within the volume, weight and power constraints of a platform similar to GOES-N while delivering 100 times more data and radiometric quality than the GOES-N imager. The higher data rate probably requires its own ground station, which could serve as a systems prototype for NOAA's next generation of operational satellites. For operational compatibility, our proposed advanced GOES imaging system contains the GOES-R requirements as a subset, and the GOES-N imager capabilities (and the sounder's imaging channels) as a further subset.

  15. Fibre-optic coupling to high-resolution CCD and CMOS image sensors

    NASA Astrophysics Data System (ADS)

    van Silfhout, R. G.; Kachatkou, A. S.

    2008-12-01

    We describe a simple method of gluing fibre-optic faceplates to complementary metal oxide semiconductor (CMOS) active pixel and charge coupled device (CCD) image sensors and report on their performance. Cross-sectional cuts reveal that the bonding layer has a thickness close to the diameter of the individual fibres and is uniform over the whole sensor area. Our method requires no special tools or alignment equipment and gives reproducible and high-quality results. The method maintains a uniform bond layer thickness even if sensor dies are mounted at slight angles with their package. These fibre-coupled sensors are of particular interest to X-ray imaging applications but also provide a solution for compact optical imaging systems.

  16. Object-oriented programming approach to CCD data acquisition and image processing

    NASA Astrophysics Data System (ADS)

    Naidu, B. Nagaraja; Srinivasan, R.; Shankar, S. Murali

    1997-10-01

    In the recent past both the CCD camera controller hardware and software have witnessed a dynamic change to keep pace with the astronomer's imaging requirements. Conventional data acquisition software is based on menu driven programs developed using structured high level languages in non-window environment. An application under windows offers several advantages to the users, over the non-window approach, like multitasking, accessing large memory and inter-application communication. Windows also provides many programming facilities to the developers such as device-independent graphics, support to wide range of input/output devices, menus, icons, bitmaps. However, programming for windows environment under structured programming demands an in-depth knowledge of events, formats, handles and inner workings. Object-oriented approach simplifies the task of programming for windows by using object windows which manage the message- processing behavior and insulate the developer from the details of inner workings of windows. As a result, a window application can be developed in much less time and effort compared to conventional approaches. We have designed and developed an easy-to-use CCD data acquisition and processing software under Microsoft Windows 3.1 operating environment using object-Pascal for windows. The acquisition software exploits the advantages of the objects to provide custom specific tool boxes to implement different functions of CCD data accusation and image processing. In this paper the hierarchy of the software structure and various application functions are presented. The flexibility of the software to handle different CCDs and also mosaic arrangement is illustrated.

  17. Controlled charge extraction—antiblooming capabilities in pnCCD imaging sensors

    NASA Astrophysics Data System (ADS)

    Schmidt, J.; Hartmann, R.; Holl, P.; Huth, M.; Lutz, G.; Pietsch, U.; Ryll, H.; Send, S.; Simson, M.; Soltau, H.; Soltau, J.; Steigenhöfer, D.; Strüder, L.

    2016-01-01

    Blooming in a CCD occurs when the signal charges accumulating in a pixel exceed the pixel saturation level and spill over into adjacent pixels. They start to spill over the weakest threshold in the electric potential of the pixel structure resulting in a degradation of the spatial information. With antiblooming mechanisms, the spatial resolution of the incoming photons can be preserved, but the intensity information is lost in the overflowing pixels. For imaging experiments, relying on a precise image structure, the preservation of the spatial resolution at the expense of precise intensity information is a workable compromise. In contrast to insulated gate CCDs, notably MOSCCDs, the potential wells of the pixel array of a pnCCD are created by p+n junctions, allowing direct electric access to the pixel structure. This allows to directly drain off charges from the pixels and to define a drain level by applying the appropriate operation voltages. Charge packets from 1 000 to more than one billion signal electrons per readout frame were generated without observing a spillover into adjacent pixels. As soon as the saturation level of the pixel is reached, the excess charge carriers are removed through charge drains exclusively created with the modification of the electric potential of the pnCCD by the operation voltages. No additional antiblooming structures were implemented in the device and the pixel full well capacity of approximately 300 000 electrons in standard operation mode was preserved. A physical model of the antiblooming mechanism of pnCCDs with a pixel size of 75 μ m × 75 μ m was established by two-dimensional numerical device simulations and verified by experiments.

  18. Holographic particle image velocimetry: signal recovery from under-sampled CCD data

    NASA Astrophysics Data System (ADS)

    Coupland, J. M.

    2004-04-01

    Holographic particle image velocimetry (HPIV) has now been demonstrated by several research groups as a method to make three-component velocity measurements from a three-dimensional fluid flow field. More recently digital HPIV has become a hot topic with the promise of near-real-time measurements without the often cumbersome optics and wet processing associated with traditional holographic methods. It is clear, however, that CCD cameras have a limited number of pixels and are not capable of resolving more than a small fraction of the interference pattern that is recorded by a typical particulate hologram. In this paper, we consider under-sampling of the interference pattern to reduce the information content and to allow recordings to be made on a CCD sensor. We describe the basic concept of model fitting to under-sampled data and demonstrate signal recovery through computer simulation. A three-dimensional analysis shows that in general, periodic sampling strategies can result in multiple particle images in the reconstruction. It is shown, however, that the significance of these peaks is reduced in the case of high numerical aperture (NA) reconstruction and can be virtually eliminated by dithering the position of sampling apertures.

  19. Development of proton CT imaging system using plastic scintillator and CCD camera.

    PubMed

    Tanaka, Sodai; Nishio, Teiji; Matsushita, Keiichiro; Tsuneda, Masato; Kabuki, Shigeto; Uesaka, Mitsuru

    2016-06-01

    A proton computed tomography (pCT) imaging system was constructed for evaluation of the error of an x-ray CT (xCT)-to-WEL (water-equivalent length) conversion in treatment planning for proton therapy. In this system, the scintillation light integrated along the beam direction is obtained by photography using the CCD camera, which enables fast and easy data acquisition. The light intensity is converted to the range of the proton beam using a light-to-range conversion table made beforehand, and a pCT image is reconstructed. An experiment for demonstration of the pCT system was performed using a 70 MeV proton beam provided by the AVF930 cyclotron at the National Institute of Radiological Sciences. Three-dimensional pCT images were reconstructed from the experimental data. A thin structure of approximately 1 mm was clearly observed, with spatial resolution of pCT images at the same level as that of xCT images. The pCT images of various substances were reconstructed to evaluate the pixel value of pCT images. The image quality was investigated with regard to deterioration including multiple Coulomb scattering. PMID:27191962

  20. Development of proton CT imaging system using plastic scintillator and CCD camera

    NASA Astrophysics Data System (ADS)

    Tanaka, Sodai; Nishio, Teiji; Matsushita, Keiichiro; Tsuneda, Masato; Kabuki, Shigeto; Uesaka, Mitsuru

    2016-06-01

    A proton computed tomography (pCT) imaging system was constructed for evaluation of the error of an x-ray CT (xCT)-to-WEL (water-equivalent length) conversion in treatment planning for proton therapy. In this system, the scintillation light integrated along the beam direction is obtained by photography using the CCD camera, which enables fast and easy data acquisition. The light intensity is converted to the range of the proton beam using a light-to-range conversion table made beforehand, and a pCT image is reconstructed. An experiment for demonstration of the pCT system was performed using a 70 MeV proton beam provided by the AVF930 cyclotron at the National Institute of Radiological Sciences. Three-dimensional pCT images were reconstructed from the experimental data. A thin structure of approximately 1 mm was clearly observed, with spatial resolution of pCT images at the same level as that of xCT images. The pCT images of various substances were reconstructed to evaluate the pixel value of pCT images. The image quality was investigated with regard to deterioration including multiple Coulomb scattering.

  1. Performance of a slow-scan CCD camera for macromolecular imaging in a 400 kV electron cryomicroscope.

    PubMed

    Sherman, M B; Brink, J; Chiu, W

    1996-04-01

    The feasibility and limitations of a 1024 x 1024 slow-scan charge-coupled device (CCD) camera were evaluated for imaging in a 400kV electron cryomicroscope. Catalase crystals and amorphous carbon film were used as test specimens. Using catalase crystals, it was found that the finite (24 microns) pixel size of the slow-scan CCD camera governs the ultimate resolution in the acquired images. For instance, spot-scan images of ice-embedded catalase crystals showed resolutions of 8 A and 4 A at effective magnifications of 67,000 x and 132,000 x, respectively. Using an amorphous carbon film, the damping effect of the modulation transfer function (MTF) of the slow-scan CCD camera on the specimen's Fourier spectrum relative to that of the photographic film was evaluated. The MTF of the slow-scan CCD camera fell off more rapidly compared to that of the photographic film and reached the value of 0.2 at the Nyquist frequency. Despite this attenuation, the signal-to-noise ratio of the CCD data, as determined from reflections of negatively-stained catalase crystals, was found to decrease to approximately 50% of that of photographic film data. The phases computed from images of the same negatively-stained catalase crystals recorded consecutively on both the slow-scan CCD camera and photographic film were found to be comparable to each other within 12 degrees. Ways of minimizing the effect of the MTF of the slow-scan CCD camera on the acquired images are also presented. PMID:8858867

  2. Quantification winter wheat LAI with HJ-1CCD image features over multiple growing seasons

    NASA Astrophysics Data System (ADS)

    Li, Xinchuan; Zhang, Youjing; Luo, Juhua; Jin, Xiuliang; Xu, Ying; Yang, Wenzhi

    2016-02-01

    Remote sensing images are widely used to map leaf area index (LAI) continuously over landscape. The objective of this study is to explore the ideal image features from Chinese HJ-1 A/B CCD images for estimating winter wheat LAI in Beijing. Image features were extracted from such images over four seasons of winter wheat growth, including five vegetation indices (VIs), principal components (PC), tasseled cap transformations (TCT) and texture parameters. The LAI was significantly correlated with the near-infrared reflectance band, five VIs [normalized difference vegetation index, enhanced vegetation index (EVI), modified nonlinear vegetation index (MNLI), optimization of soil-adjusted vegetation index, and ratio vegetation index], the first principal component (PC1) and the second TCT component (TCT2). However, these image features cannot significantly improve the estimation accuracy of winter wheat LAI in conjunction with eight texture measures. To determine the few ideal features with the best estimation accuracy, partial least squares regression (PLSR) and variable importance in projection (VIP) were applied to predict LAI values. Four remote sensing features (TCT2, PC1, MNLI and EVI) were chosen based on VIP values. The result of leave-one-out cross-validation demonstrated that the PLSR model based on these four features produced better result than the ten features' model, throughout the whole growing season. The results of this study suggest that selecting a few ideal image features is sufficient for LAI estimation.

  3. Photon counting imaging and centroiding with an electron-bombarded CCD using single molecule localisation software

    NASA Astrophysics Data System (ADS)

    Hirvonen, Liisa M.; Barber, Matthew J.; Suhling, Klaus

    2016-06-01

    Photon event centroiding in photon counting imaging and single-molecule localisation in super-resolution fluorescence microscopy share many traits. Although photon event centroiding has traditionally been performed with simple single-iteration algorithms, we recently reported that iterative fitting algorithms originally developed for single-molecule localisation fluorescence microscopy work very well when applied to centroiding photon events imaged with an MCP-intensified CMOS camera. Here, we have applied these algorithms for centroiding of photon events from an electron-bombarded CCD (EBCCD). We find that centroiding algorithms based on iterative fitting of the photon events yield excellent results and allow fitting of overlapping photon events, a feature not reported before and an important aspect to facilitate an increased count rate and shorter acquisition times.

  4. Photon counting imaging and centroiding with an electron-bombarded CCD using single molecule localisation software

    PubMed Central

    Hirvonen, Liisa M.; Barber, Matthew J.; Suhling, Klaus

    2016-01-01

    Photon event centroiding in photon counting imaging and single-molecule localisation in super-resolution fluorescence microscopy share many traits. Although photon event centroiding has traditionally been performed with simple single-iteration algorithms, we recently reported that iterative fitting algorithms originally developed for single-molecule localisation fluorescence microscopy work very well when applied to centroiding photon events imaged with an MCP-intensified CMOS camera. Here, we have applied these algorithms for centroiding of photon events from an electron-bombarded CCD (EBCCD). We find that centroiding algorithms based on iterative fitting of the photon events yield excellent results and allow fitting of overlapping photon events, a feature not reported before and an important aspect to facilitate an increased count rate and shorter acquisition times. PMID:27274604

  5. Texas Instruments /TI/ 800 x 800 charge-coupled device /CCD/ image sensor

    NASA Technical Reports Server (NTRS)

    Blouke, M. M.; Hall, J. E.; Cowens, M. W.; Janesick, J. R.

    1981-01-01

    Very-large area high-performance CCD image sensors with 800 x 800 pixel format have been successfully fabricated and operated on the basis of a three-level polysilicon gate technology. They are thinned to 8 microns over the entire 12.2 x 12.2 mm active area, and are used in the rear illumination mode. The light transfer characteristic has a gamma value of 1.000 + or - 0.002 over most of the dynamic range. Analysis of the noise behavior shows that the device SNR is shot-noise-limited over most of the dynamic range. Simple on-chip signal processing can be performed using an integration well to noiselessly collect signal charge from multiple pixels prior to reading out the charge. A UV-sensitive phosphor has been applied to the chip, yielding a device capable of imaging at wavelengths from the vacuum UV to the near IR.

  6. Effects On Beam Alignment Due To Neutron-Irradiated CCD Images At The National Ignition Facility

    SciTech Connect

    Awwal, A; Manuel, A; Datte, P; Burkhart, S

    2011-02-28

    The 192 laser beams in the National Ignition Facility (NIF) are automatically aligned to the target-chamber center using images obtained through charged coupled device (CCD) cameras. Several of these cameras are in and around the target chamber during an experiment. Current experiments for the National Ignition Campaign are attempting to achieve nuclear fusion. Neutron yields from these high energy fusion shots expose the alignment cameras to neutron radiation. The present work explores modeling and predicting laser alignment performance degradation due to neutron radiation effects, and demonstrates techniques to mitigate performance degradation. Camera performance models have been created based on the measured camera noise from the cumulative single-shot fluence at the camera location. We have found that the effect of the neutron-generated noise for all shots to date have been well within the alignment tolerance of half a pixel, and image processing techniques can be utilized to reduce the effect even further on the beam alignment.

  7. Digital image measurement of specimen deformation based on CCD cameras and Image J software: an application to human pelvic biomechanics

    NASA Astrophysics Data System (ADS)

    Jia, Yongwei; Cheng, Liming; Yu, Guangrong; Lou, Yongjian; Yu, Yan; Chen, Bo; Ding, Zuquan

    2008-03-01

    A method of digital image measurement of specimen deformation based on CCD cameras and Image J software was developed. This method was used to measure the biomechanics behavior of human pelvis. Six cadaveric specimens from the third lumbar vertebra to the proximal 1/3 part of femur were tested. The specimens without any structural abnormalities were dissected of all soft tissue, sparing the hip joint capsules and the ligaments of the pelvic ring and floor. Markers with black dot on white background were affixed to the key regions of the pelvis. Axial loading from the proximal lumbar was applied by MTS in the gradient of 0N to 500N, which simulated the double feet standing stance. The anterior and lateral images of the specimen were obtained through two CCD cameras. Based on Image J software, digital image processing software, which can be freely downloaded from the National Institutes of Health, digital 8-bit images were processed. The procedure includes the recognition of digital marker, image invert, sub-pixel reconstruction, image segmentation, center of mass algorithm based on weighted average of pixel gray values. Vertical displacements of S1 (the first sacral vertebrae) in front view and micro-angular rotation of sacroiliac joint in lateral view were calculated according to the marker movement. The results of digital image measurement showed as following: marker image correlation before and after deformation was excellent. The average correlation coefficient was about 0.983. According to the 768 × 576 pixels image (pixel size 0.68mm × 0.68mm), the precision of the displacement detected in our experiment was about 0.018 pixels and the comparatively error could achieve 1.11\\perthou. The average vertical displacement of S1 of the pelvis was 0.8356+/-0.2830mm under vertical load of 500 Newtons and the average micro-angular rotation of sacroiliac joint in lateral view was 0.584+/-0.221°. The load-displacement curves obtained from our optical measure system

  8. Design of Digital Controller for a CCD Camera with Dual-Speed Tracking Imaging on Same Frame

    NASA Astrophysics Data System (ADS)

    Wang, Hui-Juan; Li, Bin-Hua; Li, Yong-Ming; He, Chun

    2007-12-01

    The CCD cameras with high performance have been widely used in astronomical observations. The techniques for observing moving objects or still objects independently are mature. However, when both the moving objects (such as satellites, debris and asteroids) and still objects (such as stars) are observed at the same time via the same CCD camera, images of one kind of these two objects must be elongated in the most time. In order to solve this problem, the authors developed a novel imaging technique and a corresponding observation method. The photosensitive areas in some CCD arrays are physically divided into two or more zones. Based on these CCD arrays, the new idea can be implemented: one half of the photosensitive area is used to image the still objects in stare mode, and another half to image the moving objects in drift scan mode. It means that both moving objects and still objects can be tracked at the same time without the elongation of their images on the same CCD frame. Thus the new technique is called Dual-Speed Tracking Imaging on Same Frame (DSTIS). This paper briefly introduces the operation principle of the DSTIS CCD camera. After some discussions on the request of a digital controller for the camera, the design philosophy and basic structure of the controller are presented. Then some simulation and testing results are shown, and problems that were encountered during the simulation and testing are analyzed in detail and solved successfully. By the results of the software simulation and hardware testing, the design has been certified correctly.

  9. Delta-doped CCD's as low-energy particle detectors and imagers

    NASA Technical Reports Server (NTRS)

    Nikzad, Shouleh (Inventor); Hoenk, Michael E. (Inventor); Hecht, Michael H. (Inventor)

    2002-01-01

    The back surface of a thinned charged-coupled device (CCD) is treated to eliminate the backside potential well that appears in a conventional thinned CCD during backside illumination. The backside of the CCD includes a delta layer of high-concentration dopant confined to less than one monolayer of the crystal semiconductor. The thinned, delta-doped CCD is used to detect very low-energy particles that penetrate less than 1.0 nm into the CCD, including electrons having energies less than 1000 eV and protons having energies less than 10 keV.

  10. Handbook of CCD Astronomy

    NASA Astrophysics Data System (ADS)

    Howell, Steve B.

    2000-04-01

    This handbook constitutes a concise and accessible reference on all practical aspects of using Charge-Coupled Devices (CCDs). Starting with the electronic workings of these modern marvels, Steven Howell discusses their basic characteristics and then gives methods and examples for determining their values. While the focus is on using CCDs in professional observational astronomy, advanced amateur astronomers, and researchers in physics, chemistry, medical imaging, and remote sensing will also benefit from the material. Tables of useful and hard-to-find data, and key practical equations round off the book's treatment. For exercises and more information, log on to www.psi.edu/~howell/ccd.html.

  11. Stereo Imaging Velocimetry Technique Using Standard Off-the-Shelf CCD Cameras

    NASA Technical Reports Server (NTRS)

    McDowell, Mark; Gray, Elizabeth

    2004-01-01

    Stereo imaging velocimetry is a fluid physics technique for measuring three-dimensional (3D) velocities at a plurality of points. This technique provides full-field 3D analysis of any optically clear fluid or gas experiment seeded with tracer particles. Unlike current 3D particle imaging velocimetry systems that rely primarily on laser-based systems, stereo imaging velocimetry uses standard off-the-shelf charge-coupled device (CCD) cameras to provide accurate and reproducible 3D velocity profiles for experiments that require 3D analysis. Using two cameras aligned orthogonally, we present a closed mathematical solution resulting in an accurate 3D approximation of the observation volume. The stereo imaging velocimetry technique is divided into four phases: 3D camera calibration, particle overlap decomposition, particle tracking, and stereo matching. Each phase is explained in detail. In addition to being utilized for space shuttle experiments, stereo imaging velocimetry has been applied to the fields of fluid physics, bioscience, and colloidal microscopy.

  12. Development of three-wavelength CCD image pyrometer used for the temperature field measurements of continuous casting billets.

    PubMed

    Xie, Zhi; Bai, Haicheng

    2014-02-01

    This paper develops an imaging based three-color pyrometer for the monitoring of temperature distribution in a continuous casting billet. A novel optical device, together with an embedded electronic system, is designed to sequentially collect a dark image and three thermal images with specified wavelengths on a same monochromatic charge-coupled-device (CCD). The three thermal images provide the basis for the determination of target temperature, while the dark image is used to online eliminate the dark noise of CCD with a differential method. This image pyrometer is not only independent of target emissivity but also overcomes the dissimilarity of measuring accuracy between the micro-sensors of CCD resulted from the non-uniformity of pixels' intensity response and the vignetting of optical system. Furthermore, a precise two-color temperature field measuring model on the CCD pyrometer is established, based on which a self-adaptive light-integration mechanism is presented. Compared with the traditional fixed light-integration method, the measuring range of the pyrometer is greatly extended and its sensitivity in low temperature segment is improved. The test results in a steel factory demonstrate that the pyrometer is capable of meeting the requirement of surface temperature measurements about casting billets. Reliability and accuracy of measurement results are also discussed herein. PMID:24593387

  13. Development of three-wavelength CCD image pyrometer used for the temperature field measurements of continuous casting billets

    SciTech Connect

    Xie, Zhi; Bai, Haicheng

    2014-02-15

    This paper develops an imaging based three-color pyrometer for the monitoring of temperature distribution in a continuous casting billet. A novel optical device, together with an embedded electronic system, is designed to sequentially collect a dark image and three thermal images with specified wavelengths on a same monochromatic charge-coupled-device (CCD). The three thermal images provide the basis for the determination of target temperature, while the dark image is used to online eliminate the dark noise of CCD with a differential method. This image pyrometer is not only independent of target emissivity but also overcomes the dissimilarity of measuring accuracy between the micro-sensors of CCD resulted from the non-uniformity of pixels’ intensity response and the vignetting of optical system. Furthermore, a precise two-color temperature field measuring model on the CCD pyrometer is established, based on which a self-adaptive light-integration mechanism is presented. Compared with the traditional fixed light-integration method, the measuring range of the pyrometer is greatly extended and its sensitivity in low temperature segment is improved. The test results in a steel factory demonstrate that the pyrometer is capable of meeting the requirement of surface temperature measurements about casting billets. Reliability and accuracy of measurement results are also discussed herein.

  14. CCD imaging of Comet Wilson (1987VII) - A quantitative coma analysis

    NASA Technical Reports Server (NTRS)

    Schulz, Rita; A'Hearn, Michael F.; Birch, Peter V.; Bowers, Craig; Kempin, Mark; Martin, Ralph

    1993-01-01

    Distinctive cometary components (dust, ions, and radicals) are studied on the basis of 2D, narrow-band CCD images of Comet Wilson (1987VII). The fact that Comet Wilson showed no significant structures in the neutral coma during its first perihelion passage is additional evidence for the hypothesis that dynamically new comets do not show a heterogeneous nucleus, but still have a relatively uniform surface. The deviations from the 1/rho law for the decrease of surface brightness as a function of nuclear distance are explained by a combination of short-term variations in the dust production and the effects of solar radiation pressure. The C2 production rate remains basically constant during the whole observational period, while the CN production rate decreases with increasing heliocentric distance. It is inferred that the formation of C2 might be due both to photolytic destruction of some parent molecules as well as to chemical reactions between other species.

  15. Observations of Selected Double Star Systems Using CCD Astrometry, Lucky Imaging, and Speckle Interferometry

    NASA Astrophysics Data System (ADS)

    Ariyawansa, Ashan; Troville, Jonathan

    2014-10-01

    In August 2013, a team of six undergraduate students were selected for a two week research program, Consortium for Undergraduate Research and Education in Astronomy (CUREA), at the Mount Wilson Observatory-California. Each student completed a project related to observational astronomy and a joint project was done by Ariyawansa and Troville on measuring double stars. In this project, three different methods were used to measure the angular separation and the position angle of the double stars. CCD astrometry was the first method used to measure the star system WDS17574+3540, which has been identified as a quadruple system. Lucky imaging and speckle interferometry were the other methods used to measure the systems delta Cyg, epsilon1 Lyr, epsilon2 Lyr, and WDS23595+3343 with reduction using the REDUC software package.

  16. Recent and Future Advances of Ground-based 1.5 CCD Telescope AZT-22

    NASA Astrophysics Data System (ADS)

    Pinigin, G.; Shulga, A.; Aslan, Z.; Gumerov, R.

    Current state and future programme of positional astronomy of 1.5 meter telescope `Z'-22 (1500,11600) of the Engelhardt astronomical observatory of the Kazan university (Russia) installed in Turkey (National observatory in the near of Antalia) is discussed. `Z'-22 was made by S-Petersburg optical firm LOMO in 1995 and equipped with CCD camera ST-8 and second CCD camera (1024 × 1140, 16 × 16 deg) worked in stare and drift-scan mode. First light presented observations of extra galactic radio sources, Jupiter with Callisto and Saturn with moons in 1999. It was shown a good quality of CCD frames and high positional accuracy owing to good instrumental and register parameters. The original method of the Nikolaev Axial meridian circle (AMC) and CCD `Z'-22 combination by using of covered strips connected with the extragalactic radio sources (ERS) for refinement of the optical/radio reference frames linking and for HC extension to faint stars is proposed. From another site coordinated programme could be include observations of small Solar system bodies about 16-20 magnitudes for determination of mutual orientation of dynamical frame and ICRF, selected asteroids mass; for determination of transneptunian population, large planets moons, near-Earth objects positions and brightness and so on. This work was done according by financial support of Russian foundation of basic research N99-02-06013, 99-02-17514 and Russian Federal Program ``Astronomy''.

  17. An adaptive threshold method for improving astrometry of space debris CCD images

    NASA Astrophysics Data System (ADS)

    Sun, Rong-yu; Zhao, Chang-yin

    2014-06-01

    Optical survey is a main technique for observing space debris, and precisely measuring the positions of space debris is of great importance. Due to several factors, e.g. the angle object normal to the observer, the shape as well as the attitude of the object, the variations of observed characteristics for low earth orbital space debris are distinct. When we look at optical CCD images of observed objects, the size and brightness are varying, hence it’s difficult to decide the threshold during centroid measurement and precise astrometry. Traditionally the threshold is given empirically and constantly in data reduction, and obviously it’s not suitable for data reduction of space debris. Here we offer a solution to provide the threshold. Our method assumes that the PSF (point spread function) is Gaussian and estimates the signal flux by a directly two-dimensional Gaussian fit, then a cubic spline interpolation is performed to divide each initial pixel into several sub-pixels, at last the threshold is determined by the estimation of signal flux and the sub-pixels above threshold are separated to estimate the centroid. A trail observation of the fast spinning satellite Ajisai is made and the CCD frames are obtained to test our algorithm. The calibration precision of various threshold is obtained through the comparison between the observed equatorial position and the reference one, the latter are obtained from the precise ephemeris of the satellite. The results indicate that our method reduces the total errors of measurements, it works effectively in improving the centering precision of space debris images.

  18. Design of Frame Transfer Area CCD Imaging System for Dark Objects

    NASA Astrophysics Data System (ADS)

    Zhang, Y. H.; Yan, Y. H.

    2015-05-01

    To realize the requirement of low-noise observation of the dark objects in deep-space missions, a simple and stable design method for the imaging system of space camera is proposed in this paper, and it is performed for the schematic circuit diagram design of each part of the CCD47-20 back illuminated AIMO produced by E2V company. The long exposure for the dark object observation can be realized by adjusting the delay time. The imaging system circuit uses the synchronous dynamic random access memory (SDRAM) and correlated double sampling (CDS) analog-to-digital converter (AD) which can remove the noise in the image signal. The Altera's CycloneIII EP3C25Q240C8 field programmable gate array (FPGA) is adopted as the core control device in the imaging system to write the driver, which is modularly designed and portable as well. The simulation and measurement show that the drive circuit works normally to satisfy the requirement of systematic design.

  19. Wide-field direct CCD observations supporting the Astro-1 Space Shuttle mission's Ultraviolet Imaging Telescope

    NASA Technical Reports Server (NTRS)

    Hintzen, Paul; Angione, Ron; Talbert, Freddie; Cheng, K.-P.; Smith, Eric; Stecher, Theodore P.

    1993-01-01

    Wide field direct CCD observations are being obtained to support and complement the vacuum-ultraviolet (VUV) images provided by Astro's Ultraviolet Imaging Telescope (UIT) during a Space Shuttle flight in December 1990. Because of the wide variety of projects addressed by UIT, the fields observed include (1) galactic supernova remnants such as the Cygnus Loop and globular clusters such as Omega Cen and M79; (2) the Magellanic Clouds, M33, M81, and other galaxies in the Local Group; and (3) rich clusters of galaxies, principally the Perseus cluster and Abell 1367. Ground-based observations have been obtained for virtually all of the Astro-1 UIT fields. The optical images allow identification of individual UV sources in each field and provide the long baseline in wavelength necessary for accurate analysis of UV-bright sources. To facilitate use of our optical images for analysis of UIT data and other projects, we plan to archive them, with the UIT images, at the National Space Science Data Center (NSSDC), where they will be universally accessible via anonymous FTP. The UIT, one of three telescopes comprising the Astro spacecraft, is a 38-cm f/9 Ritchey-Chretien telescope on which high quantum efficiency, solar-blind image tubes are used to record VUV images on photographic film. Five filters with passbands centered between 1250A and 2500A provide both VUV colors and a measurement of extinction via the 2200A dust feature. The resulting calibrated VUV pictures are 40 arcminutes in diameter at 2.5 arcseconds resolution. The capabilities of UIT, therefore, complement HST's WFPC: the latter has 40 times greater collecting area, while UIT's usable field has 170 times WFPC's field area.

  20. High-speed high-resolution epifluorescence imaging system using CCD sensor and digital storage for neurobiological research

    NASA Astrophysics Data System (ADS)

    Takashima, Ichiro; Kajiwara, Riichi; Murano, Kiyo; Iijima, Toshio; Morinaka, Yasuhiro; Komobuchi, Hiroyoshi

    2001-04-01

    We have designed and built a high-speed CCD imaging system for monitoring neural activity in an exposed animal cortex stained with a voltage-sensitive dye. Two types of custom-made CCD sensors were developed for this system. The type I chip has a resolution of 2664 (H) X 1200 (V) pixels and a wide imaging area of 28.1 X 13.8 mm, while the type II chip has 1776 X 1626 pixels and an active imaging area of 20.4 X 18.7 mm. The CCD arrays were constructed with multiple output amplifiers in order to accelerate the readout rate. The two chips were divided into either 24 (I) or 16 (II) distinct areas that were driven in parallel. The parallel CCD outputs were digitized by 12-bit A/D converters and then stored in the frame memory. The frame memory was constructed with synchronous DRAM modules, which provided a capacity of 128 MB per channel. On-chip and on-memory binning methods were incorporated into the system, e.g., this enabled us to capture 444 X 200 pixel-images for periods of 36 seconds at a rate of 500 frames/second. This system was successfully used to visualize neural activity in the cortices of rats, guinea pigs, and monkeys.

  1. Weak Lensing PSF Correction of Wide-field CCD Mosaic Images (SULI Paper)

    SciTech Connect

    Cevallos, Marissa; /Caltech /SLAC

    2006-01-04

    Gravitational lensing provides some of the most compelling evidence for the existence of dark matter. Dark matter on galaxy cluster scales can be mapped due to its weak gravitational lensing effect: a cluster mass distribution can be inferred from the net distortion of many thousands of faint background galaxies that it induces. Because atmospheric aberration and defects in the detector distort the apparent shape of celestial objects, it is of great importance to characterize accurately the point spread function (PSF) across an image. In this research, the PSF is studied in images from the Canada-France-Hawaii Telescope (CFHT), whose camera is divided into 12 CCD chips. Traditional weak lensing methodology involves averaging the PSF across the entire image: in this work we investigate the effects of measuring the PSF in each chip independently. This chip-by-chip analysis was found to reduce the strength of the correlation between star and galaxy shapes, and predicted more strongly the presence of known galaxy clusters in mass maps. These results suggest correcting the CFHT PSF on an individual chip basis significantly improves the accuracy of detecting weak lensing.

  2. CCD Centroiding Experiment for Correcting a Distorted Image on the Focal Plane

    NASA Astrophysics Data System (ADS)

    Yano, Taihei; Araki, Hiroshi; Gouda, Naoteru; Kobayashi, Yukiyasu; Tsujimoto, Takuji; Nakajima, Tadashi; Kawano, Nobuyuki; Tazawa, Seiichi; Yamada, Yoshiyuki; Hanada, Hideo; Asari, Kazuyoshi; Tsuruta, Seiitsu

    2006-10-01

    JASMINE (Japan Astrometry Satellite Mission for Infrared Exploration) and ILOM (In situ Lunar Orientation Measurement) are space missions that are in progress at the National Astronomical Observatory of Japan. These two projects require a common astrometric technique to obtain precise positions of star images on solid-state detectors in order to accomplish their objectives. In the laboratory, we have carried out measurements of the centroid of artificial star images on a CCD array in order to investigate the precision of the positions of the stars, using an algorithm for estimating them from photon-weighted means of the stars. In the calibration of the position of a star image at the focal plane, we have also taken into account the lowest order distortion due to optical aberrations, which is proportional to the cube of the distance from the optical axis. Accordingly, we find that the precision of the measurement for the positions of the stars reaches below 1/100 pixel for one measurement.

  3. Reducing Scattered Light in CCD Images at the CTIO 0.9m Telescope

    NASA Astrophysics Data System (ADS)

    Barnaby, D.; Rauscher, B. J.

    1998-12-01

    We have been studying luminous halos around spiral galaxies in very deep near-infrared K-band images (limiting surface brightness =24 mag arcsec(-2) ; lambda_ {c} = 2.35 mu m). Following our successful detection of a halo around the southern spiral galaxy ESO 240-G11 (Rauscher et al. 1998), we collected optical CCD images of candidate galaxies at the Cerro Tololo Interamerican Observatory (CTIO) 0.9 m telescope from 17-21 Sept 1998. Because light scattered by the telescope can mask or mimic faint, extended emission, we took precautions to minimize stray and scattered light. To assess the amount of scattered light, we collected images of the telescope pupil using a pinhole camera, which we constructed by laying a sheet of aluminum foil, perforated with a submillimeter hole, 19 mm in front of the CCD. These images showed that the telescope did scatter light on the order of a few percent over a radius of about 2 arcminutes. Supressing this extraneous light was highly desirable, since halo surface brightness can be < 0.2% of the disk central surface brightness. To reduce the scattered light, the staff of CTIO and we added 3 baffles. One baffle consisted of a 0.95 m diameter tube added as an extension to the telescope, which has a closed-tube design. The other 2 baffles were diaphragms mounted between the primary baffle (the ``chimney'') and the shutter. These baffles effectively eliminated the largest sources of scattered light, which appear to be the edge of the secondary baffle and the inner surface of the chimney (Figure 1, http:// astro.uchicago.edu/home/web/barnaby/sctrdlite98.html). In this paper, we quantify the reduction in scattered light and examine the most useful location to add baffles to this telescope. Acknowledgements. We thank the CTIO Telescope Operations staff for their help in constructing and installing the baffles. We also thank support astronomer Nick Suntzeff for suggesting the pinhole tests. Rauscher, B. J. et al. 1998, ApJ, 506, 116

  4. Computer-vision-based weed identification of images acquired by 3CCD camera

    NASA Astrophysics Data System (ADS)

    Zhang, Yun; He, Yong; Fang, Hui

    2006-09-01

    Selective application of herbicide to weeds at an earlier stage in crop growth is an important aspect of site-specific management of field crops. For approaches more adaptive in developing the on-line weed detecting application, more researchers involves in studies on image processing techniques for intensive computation and feature extraction tasks to identify the weeds from the other crops and soil background. This paper investigated the potentiality of applying the digital images acquired by the MegaPlus TM MS3100 3-CCD camera to segment the background soil from the plants in question and further recognize weeds from the crops using the Matlab script language. The image of the near-infrared waveband (center 800 nm; width 65 nm) was selected principally for segmenting soil and identifying the cottons from the thistles was achieved based on their respective relative area (pixel amount) in the whole image. The results show adequate recognition that the pixel proportion of soil, cotton leaves and thistle leaves were 78.24%(-0.20% deviation), 16.66% (+ 2.71% SD) and 4.68% (-4.19% SD). However, problems still exists by separating and allocating single plants for their clustering in the images. The information in the images acquired via the other two channels, i.e., the green and the red bands, need to be extracted to help the crop/weed discrimination. More optical specimens should be acquired for calibration and validation to establish the weed-detection model that could be effectively applied in fields.

  5. Dynamic MTF improvement scheme and its validation for CCD operating in TDI mode for Earth imaging applications

    NASA Astrophysics Data System (ADS)

    Dubey, Neeraj; Banerjee, Arup

    2016-05-01

    The paper presents the scheme for improving the image contrast in the remote sensing images and highlights the novelty in hardware & software design in the test system developed for measuring image contrast function. Modulation transfer function (MTF) is the most critical quality element of the high-resolution imaging payloads for earth observation consisting of TDI-CCD (Time Delayed Integration Charge Coupled Device) image. From the mathematical model for MTF Smear MTF of 65% (35% degradation) is observed. Then a operating method for TDI-CCD is developed, using which 96% of Motion Smear MTF will occur within the imaging operation. As a major part of the validation, indigenously designed and developed a test system for measuring the dynamic MTF of TDI Sensors which consists of the optical scanning system, TDI-CCD camera drive & video processing electronics, thermal control system and telecentric uniform illumination system. The experimental results confirm that image quality improvement can be achieved by this method. This method is now implemented in the flight model hardware of the remote sensing payload.

  6. The utility of texture analysis to improve per-pixel classification for CBERS02's CCD image

    NASA Astrophysics Data System (ADS)

    Peng, Guangxiong; He, Yuhua; Li, Jing; Chen, Yunhao; Hu, Deyong

    2006-10-01

    The maximum likelihood classification (MLC) is one of the most popular methods in remote sensing image classification. Because the maximum likelihood classification is based on spectrum of objects, it cannot correctly distinguish objects that have same spectrum and cannot reach the accuracy requirement. In this paper, we take an area of Langfang of Hebei province in China as an example and discuss the method of combining texture of panchromatic image with spectrum to improve the accuracy of CBERS02 CCD image information extraction. Firstly, analysis of the textures of the panchromatic image (CCD5) made by using texture analysis of Gray Level Coocurrence Matrices and statistic index. Then optimal texture window size of angular second moment, contrast, entropy and correlation is obtained according to variation coefficient of each texture measure for each thematic class. The chosen optimal window size is that from which the value of variation coefficient starts to stabilize while having the smallest value. The output images generated by texture analysis are used as additional bands together with other multi-spectral bands(CCD1-4) in classification. Objects that have same spectrums can be distinguished. Finally, the accuracy measurement is compared with the classification based on spectrum only .The result indicates that the objects with same spectrum are distinguished by using texture analysis in image classification, and the spectral /textural combination improves more than spectrum only in classification accuracy.

  7. Preliminary results of SAR image compression using MatrixViewTM on coherent change detection (CCD) analysis

    NASA Astrophysics Data System (ADS)

    Gresko, Lawrence S.; Gorham, LeRoy A.; Thiagarajan, Arvind

    2012-05-01

    An investigation was made into the feasibility of compressing complex Synthetic Aperture Radar (SAR) images using MatrixViewTM compression technology to achieve higher compression ratios than previously achieved. Complex SAR images contain both amplitude and phase information that are severely degraded with traditional compression techniques. This phase and amplitude information allows interferometric analysis to detect minute changes between pairs of SAR images, but is highly sensitive to any degradation in image quality. This sensitivity provides a measure to compare capabilities of different compression technologies. The interferometric process of Coherent Change Detection (CCD) is acutely sensitive to any quality loss and, therefore, is a good measure by which to compare compression capabilities of different technologies. The best compression that could be achieved by block adaptive quantization (a classical compression approach) applied to a set of I and Q phased-history samples, was a Compression Ratio (CR) of 2x. Work by Novak and Frost [3] increased this CR to 3-4x using a more complex wavelet-based Set Partitioning In Hierarchical Trees (SPIHT) algorithm (similar in its core to JPEG 2000). In each evaluation as the CR increased, degradation occurred in the reconstituted image measured by the CCD image coherence. The maximum compression was determined at the point the CCD image coherence remained > 0.9. The same investigation approach using equivalent sample data sets was performed using an emerging technology and product called MatrixViewTM. This paper documents preliminary results of MatrixView's compression of an equivalent data set to demonstrate a CR of 10-12x with an equivalent CCD coherence level of >0.9: a 300-400% improvement over SPIHT.

  8. Measurement of time varying temperature fields using visible imaging CCD cameras

    SciTech Connect

    Keanini, R.G.; Allgood, C.L.

    1996-12-31

    A method for measuring time-varying surface temperature distributions using high frame rate visible imaging CCD cameras is described. The technique is based on an ad hoc model relating measured radiance to local surface temperature. This approach is based on the fairly non-restrictive assumptions that atmospheric scattering and absorption, and secondary emission and reflection are negligible. In order to assess performance, both concurrent and non-concurrent calibration and measurement, performed under dynamic thermal conditions, are examined. It is found that measurement accuracy is comparable to the theoretical accuracy predicted for infrared-based systems. In addition, performance tests indicate that in the experimental system, real-time calibration can be achieved while real-time whole-field temperature measurements require relatively coarse spatial resolution. The principal advantages of the proposed method are its simplicity and low cost. In addition, since independent temperature measurements are used for calibration, emissivity remains unspecified, so that a potentially significant source of error is eliminated.

  9. Steam wetness measurement using CCD imaging methods in low-pressure turbine

    NASA Astrophysics Data System (ADS)

    Wu, Wei; Qin, Shiqiao; Huang, Zhuqing; Wang, Xingshu; Hu, Chunsheng

    2010-11-01

    The steam flow in low-pressure turbine contained abundant water droplets, which will decrease the work efficiency and pose potential threaten to operation safety, so measurement of steam wetness has brought great interest in electricity generation industry. In this paper, a new measuring method using CCD (Charge Coupled Device) imaging technique was proposed to determine the wetness in steam turbine based on the forward small angle light scattering theory. A simulated steam turbine facility was designed to generate the wet steam, and light scattering experiments were carried out at various working conditions in this device. The steam wetness parameters and droplet size distribution were obtained by means of numerical inversion of the light intensity distribution based on Mie scattering theory. The results demonstrate that the obtained data from the present analysis is in good agreement with the results of the theory analysis and previous study, and the proposed method is proved to be suitable for steam wetness measuring and monitoring by further development.

  10. A Channel Stop Defined, Barrier And Drain Antiblooming Structure For Virtual Phase Ccd Image Sensors

    NASA Astrophysics Data System (ADS)

    Keenan, W. F.; Hosack, H. H.

    1987-04-01

    A new barrier and drain antiblooming architecture has been developed for virtual phase CCD image sensors. In this structure the drain is isolated from the pixel wells by the channel stop implant except in the antiblooming control region, where it is the same as the normal pixel barrier which exists along the direction of charge transfer. In addition, in this structure the drain is placed beneath the virtual electrode to eliminate low voltage breakdown effects. The unique organization of this structure allows the same potential levels to be used in both the antiblooming barrier and the transfer barrier. This multiple use of the same potential region greatly simplifies the processing needed for this type of device. The structure is formed by the process steps normally used to fabricate the sensor without antiblooming, except for one additional ion implant and pattern level to form the antiblooming drain. The antibooming action is continuous during integration and readout, and has extremely high overload tolerance. These features make this structure the preferred form of antiblooming for applications which have very high overload, such as flash lamp illumination. The process economy inherent in this anti-blooming structure results in higher sensor yields and lower manufacturing costs.

  11. Classification of volcanic ash particles from Sakurajima volcano using CCD camera image and cluster analysis

    NASA Astrophysics Data System (ADS)

    Miwa, T.; Shimano, T.; Nishimura, T.

    2012-12-01

    Quantitative and speedy characterization of volcanic ash particle is needed to conduct a petrologic monitoring of ongoing eruption. We develop a new simple system using CCD camera images for quantitatively characterizing ash properties, and apply it to volcanic ash collected at Sakurajima. Our method characterizes volcanic ash particles by 1) apparent luminance through RGB filters and 2) a quasi-fractal dimension of the shape of particles. Using a monochromatic CCD camera (Starshoot by Orion Co. LTD.) attached to a stereoscopic microscope, we capture digital images of ash particles that are set on a glass plate under which white colored paper or polarizing plate is set. The images of 1390 x 1080 pixels are taken through three kinds of color filters (Red, Green and Blue) under incident-light and transmitted-light through polarizing plate. Brightness of the light sources is set to be constant, and luminance is calibrated by white and black colored papers. About fifteen ash particles are set on the plate at the same time, and their images are saved with a bit map format. We first extract the outlines of particles from the image taken under transmitted-light through polarizing plate. Then, luminances for each color are represented by 256 tones at each pixel in the particles, and the average and its standard deviation are calculated for each ash particle. We also measure the quasi-fractal dimension (qfd) of ash particles. We perform box counting that counts the number of boxes which consist of 1×1 and 128×128 pixels that catch the area of the ash particle. The qfd is estimated by taking the ratio of the former number to the latter one. These parameters are calculated by using software R. We characterize volcanic ash from Showa crater of Sakurajima collected in two days (Feb 09, 2009, and Jan 13, 2010), and apply cluster analyses. Dendrograms are formed from the qfd and following four parameters calculated from the luminance: Rf=R/(R+G+B), G=G/(R+G+B), B=B/(R+G+B), and

  12. Electro-optical testing of fully depleted CCD image sensors for the Large Synoptic Survey Telescope camera

    NASA Astrophysics Data System (ADS)

    Doherty, Peter E.; Antilogus, Pierre; Astier, Pierre; Chiang, James; Gilmore, D. Kirk; Guyonnet, Augustin; Huang, Dajun; Kelly, Heather; Kotov, Ivan; Kubanek, Petr; Nomerotski, Andrei; O'Connor, Paul; Rasmussen, Andrew; Riot, Vincent J.; Stubbs, Christopher W.; Takacs, Peter; Tyson, J. Anthony; Vetter, Kurt

    2014-07-01

    The LSST Camera science sensor array will incorporate 189 large format Charge Coupled Device (CCD) image sensors. Each CCD will include over 16 million pixels and will be divided into 16 equally sized segments and each segment will be read through a separate output amplifier. The science goals of the project require CCD sensors with state of the art performance in many aspects. The broad survey wavelength coverage requires fully depleted, 100 micrometer thick, high resistivity, bulk silicon as the imager substrate. Image quality requirements place strict limits on the image degradation that may be caused by sensor effects: optical, electronic, and mechanical. In this paper we discuss the design of the prototype sensors, the hardware and software that has been used to perform electro-optic testing of the sensors, and a selection of the results of the testing to date. The architectural features that lead to internal electrostatic fields, the various effects on charge collection and transport that are caused by them, including charge diffusion and redistribution, effects on delivered PSF, and potential impacts on delivered science data quality are addressed.

  13. Analysis of the detective quantum efficiency of coupling a CCD to a scintillating phosphor for x-ray microtomographic imaging

    NASA Astrophysics Data System (ADS)

    Westmore, Michael S.; Cunningham, Ian A.

    1993-09-01

    We are developing an x-ray microtomographic imaging system ((mu) CT) for imaging small objects at very high (approximately 25 micrometers ) spatial resolution. The detector for this system consists of a CCD array coupled to a phosphor screen through a fiber-optic faceplate. For the purposes of signal and noise analysis, this system is modeled as a multi-stage cascaded imaging system consisting of: (a) conversion of x-ray quanta to optical quanta in the phosphor; (b) collection and transfer of optical quanta from the phosphor to the CCD; and (c) detection of optical quanta by the CCD. We use the model of Rabbani et al. for cascaded systems to theoretically calculate the detective quantum efficiency (DQE) as a function of spatial frequency. We have developed the theoretical basis of a spatial-frequency dependent nomogram in terms of the system DQE. This approach is used to identify any sources of image degradation, and to make optimal design decisions of system parameters such as optical gains or numerical apertures. Using this approach, we show that the spreading of optical photons in the phosphor screen is the most significant factor degrading the MTF.

  14. Performance of x-ray imaging systems with optical coupling for demagnification between scintillator and CCD readout

    NASA Astrophysics Data System (ADS)

    Roehrig, Hans; Yu, Tong; Schempp, William V.

    1994-11-01

    This paper discusses the performance of x-ray imaging devices employing optical coupling between the x-ray detector (phosphor screen) and the readout (CCD). Optical coupling can be performed with the aid of a lens or with the aid of a fiber-optic taper. Conventional wisdom predicts that fiber-optic coupling is superior on account of superior light collection efficiency. For the same demagnification, fiber-optic tapers usually have a higher numerical aperture in the object plane than a lens. This paper presents a review of critical imaging system components and provides a comparison of factors such as light collection efficiency, phosphor screen light output and CCD sensitivity. The paper presents data obtained with two commercially available x-ray imaging systems, one a lens coupled system, the other a fiber- optically coupled system. These systems are used for mammographically guided stereotactic breast biopsy to determine the x-, y-, and z-coordinates of the lesion to be biopsied. The paper concludes that a lens coupled x-ray imaging system can be superior to a fiber-optic one, particularly with respect to Detective Quantum Efficiency. This superiority is based on a quantum gain of about 5 CCD electrons per absorbed x-ray photon, which is (however barely) sufficient to preserve most of the information collected by the system's Lanex screen.

  15. A CCD/CMOS process for integrated image acquisition and early vision signal processing

    NASA Astrophysics Data System (ADS)

    Keast, Craig L.; Sodini, Charles G.

    The development of technology which integrates a four phase, buried-channel CCD in an existing 1.75 micron CMOS process is described. The four phase clock is employed in the integrated early vision system to minimize process complexity. Signal corruption is minimized and lateral fringing fields are enhanced by burying the channel. The CMOS process for CCD enhancement is described, which highlights a new double-poly process and the buried channel, and the integration is outlined. The functionality and transfer efficiency of the process enhancement were appraised by measuring CCD shift registers at 100 kHz. CMOS measurement results are presented, which include threshold voltages, poly-to-poly capacitor voltage and temperature coefficients, and dark current. A CCD/CMOS processor is described which combines smoothing and segmentation operations. The integration of the CCD and the CMOS processes is found to function due to the enhancement-compatible design of the CMOS process and the thorough employment of CCD module baseline process steps.

  16. Analysis of Lab-Scale Drainage and Imbibition Experiments with ERT and High Resolution CCD Imaging

    NASA Astrophysics Data System (ADS)

    Breen, S. J.; Detwiler, R. L.; Carrigan, C. R.

    2012-12-01

    Field-scale studies have shown Electrical Resistivity Tomography (ERT) to be an effective tool for imaging resistivity anomalies such as those caused by infiltration events or migration of conductive solutes. However, the actual distribution of parameters of interest (e.g., saturation or ion concentration) is rarely known at field sites, and therefore the accuracy of ERT inversion results is difficult to assess quantitatively. Lab-scale experiments provide the opportunity to test ERT in controlled environments, where the true parameter distributions can be better constrained and even measured in real time. We present results from analog bench-scale experiments aimed at evaluating the ability of ERT to quantify the spatial distribution of water during repeated drainage and imbibition cycles in a near-uniform porous medium. Our experiments represent a well-controlled analog for field-scale processes. We inject and withdraw measured volumes of water (resistivity similar to groundwater) into translucent chambers filled with quartz sand and lined with electrodes. Once the chamber is fully saturated, imbibition and drainage cycles are carried out. Simultaneously, a CCD camera captures high-resolution images, and an ERT data acquisition system scans the chamber. Processing of the CCD images using quantitative visualization techniques results in high-resolution measurements of the spatial distribution of the water, which are compared directly to inverted resistivity fields to quantitatively evaluate the accuracy of the ERT inversions. Thus, these experiments combine the two key advantages of numerical studies and field studies: 1) independent saturation measurements and 2) real, non-synthetic, ERT data. They also allow a high degree of control over the physical processes under investigation. Results from recent ERT data taken during gas injection experiments into a brine-saturated background showed reasonably high sensitivity to the spatial distribution of electrically

  17. Evaluation of imaging performance of a taper optics CCD; FReLoN' camera designed for medical imaging.

    PubMed

    Coan, Paola; Peterzol, Angela; Fiedler, Stefan; Ponchut, Cyril; Labiche, Jean Claude; Bravin, Alberto

    2006-05-01

    The purpose of this work was to assess the imaging performance of an indirect conversion detector (taper optics CCD; FReLoN' camera) in terms of the modulation transfer function (MTF), normalized noise power spectrum (NNPS) and detective quantum efficiency (DQE). Measurements were made with a synchrotron radiation laminar beam at various monochromatic energies in the 20-51.5 keV range for a gadolinium-based fluorescent screen varying in thickness; data acquisition and analysis were made by adapting to this beam geometry protocols used for conventional cone beams. The pre-sampled MTFs of the systems were measured using an edge method. The NNPS of the systems were determined for a range of exposure levels by two-dimensional Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, NNPS, exposure and incoming number of photons. The MTF, for a given screen, was found to be almost energy independent and, for a given energy, higher for the thinnest screen. At 33 keV and for the 40 (100) microm screen, at 10% the MTF is 9.2 (8.6) line-pairs mm(-1). The NNPS was found to be different in the two analyzed directions in relation to frequency. Highest DQE values were found for the combination 100 microm and 25 keV (0.5); it was still equal to 0.4 at 51.5 keV (above the gadolinium K-edge). The DQE is limited by the phosphor screen conversion yield and by the CCD efficiency. At the end of the manuscript the results of the FReLoN characterization and those from a selected number of detectors presented in the literature are compared. PMID:16645252

  18. Megacam: A Wide-Field CCD Imager for the MMT and Magellan

    NASA Astrophysics Data System (ADS)

    McLeod, Brian; Geary, John; Conroy, Maureen; Fabricant, Daniel; Ordway, Mark; Szentgyorgyi, Andrew; Amato, Stephen; Ashby, Matthew; Caldwell, Nelson; Curley, Dylan; Gauron, Thomas; Holman, Matthew; Norton, Timothy; Pieri, Mario; Roll, John; Weaver, David; Zajac, Joseph; Palunas, Povilas; Osip, David

    2015-04-01

    Megacam is a large-format optical camera that can be operated at the f/5 Cassegrain foci of the MMT on Mount Hopkins, Arizona, and the Magellan Clay telescope at Las Campanas Observatory, Chile. Megacam's focal plane is composed of 36 closely packed e2v CCD42-90 CCDs, each with 2048 × 4608 pixels, assembled in an 18,432 × 18,432 array. Two additional CCD42-90s are provided for autoguiding and focus control. The CCDs have 13.5 μm square pixels that subtend 0 \\overset{''}{.} 08 at the f/5 foci, yielding a 25' × 25' field-of-view. The camera system includes a focal plane shutter, two filter wheels, two liquid nitrogen reservoirs, a central chamber that holds the CCD mosaic array, and two electronics boxes. Megacam is equipped with a variety of broadband and narrowband filters. Software features include automatic calculation of twilight flat exposure times.

  19. Image Quality of Digital Direct Flat-Panel Mammography Versus an Indirect Small-Field CCD Technique Using a High-Contrast Phantom

    PubMed Central

    Krug, Kathrin Barbara; Stützer, Hartmut; Frommolt, Peter; Boecker, Julia; Bovenschulte, Henning; Sendler, Volker; Lackner, Klaus

    2011-01-01

    Objective. To compare the detection of microcalcifications on mammograms of an anthropomorphic breast phantom acquired by a direct digital flat-panel detector mammography system (FPM) versus a stereotactic breast biopsy system utilizing CCD (charge-coupled device) technology with either a 1024 or 512 acquisition matrix (1024 CCD and 512 CCD). Materials and Methods. Randomly distributed silica beads (diameter 100–1400 μm) and anthropomorphic scatter bodies were applied to 48 transparent films. The test specimens were radiographed on a direct digital FPM and by the indirect 1024 CCD and 512 CCD techniques. Four radiologists rated the monitor-displayed images independently of each other in random order. Results. The rate of correct positive readings for the “number of detectable microcalcifications” for silica beads of 100–199 μm in diameter was 54.2%, 50.0% and 45.8% by FPM, 1024 CCD and 512 CCD, respectively. The inter-rater variability was most pronounced for silica beads of 100–199 μm in diameter. The greatest agreement with the gold standard was observed for beads >400 μm in diameter across all methods. Conclusion. Stereotactic spot images taken by 1024 matrix CCD technique are diagnostically equivalent to direct digital flat-panel mammograms for visualizing simulated microcalcifications >400 μm in diameter. PMID:22332015

  20. The low-resolution imaging spectrograph red channel CCD upgrade: fully depleted, high-resistivity CCDs for Keck

    NASA Astrophysics Data System (ADS)

    Rockosi, C.; Stover, R.; Kibrick, R.; Lockwood, C.; Peck, M.; Cowley, D.; Bolte, M.; Adkins, S.; Alcott, B.; Allen, S. L.; Brown, B.; Cabak, G.; Deich, W.,; Hilyard, D.,; Kassis, M.,; Lanclos, K.,; Lewis, J.,; Pfister, T.,; Phillips, A.,; Robinson, L.,; Saylor, M.,; Thompson, M.,; Ward, J.,; Wei, M.,; Wright, C.,

    2010-07-01

    A mosaic of two 2k x 4k fully depleted, high resistivity CCD detectors was installed in the red channel of the Low Resolution Imaging Spectrograph for the Keck-I Telescope in June, 2009 replacing a monolithic Tektronix/SITe 2k x 2k CCD. These CCDs were fabricated at Lawrence Berkeley National Laboratory (LBNL) and packaged and characterized by UCO/Lick Observatory. Major goals of the detector upgrade were increased throughput and reduced interference fringing at wavelengths beyond 800 nm, as well as improvements in the maintainability and serviceability of the instrument. We report on the main features of the design, the results of optimizing detector performance during integration and testing, as well as the throughput, sensitivity and performance of the instrument as characterized during commissioning.

  1. Photometric correction and reflectance calculation for lunar images from the Chang'E-1 CCD stereo camera.

    PubMed

    Chen, Chao; Qin, Qiming; Chen, Li; Zheng, Hong; Fa, Wenzhe; Ghulam, Abduwasit; Zhang, Chengye

    2015-12-01

    Photometric correction and reflectance calculation are two important processes in the scientific analysis and application of Chang'E-1 (CE-1) charge-coupled device (CCD) stereo camera data. In this paper, the methods of photometric correction and reflectance calculation were developed. On the one hand, in considering the specificity of datasets acquired by the CE-1 CCD stereo camera, photometric correction was conducted based on the digital number value directly using the revised Lommel-Seeliger factor. On the other hand, on the basis of laboratory-measured bidirectional reflectances, the relative reflectance was then calculated using the empirical linear model. The presented approach can be used to identify landing sites, obtain global images, and produce topographic maps of the lunar surface. PMID:26831395

  2. Advancing biomedical imaging

    PubMed Central

    Weissleder, Ralph; Nahrendorf, Matthias

    2015-01-01

    Imaging reveals complex structures and dynamic interactive processes, located deep inside the body, that are otherwise difficult to decipher. Numerous imaging modalities harness every last inch of the energy spectrum. Clinical modalities include magnetic resonance imaging (MRI), X-ray computed tomography (CT), ultrasound, and light-based methods [endoscopy and optical coherence tomography (OCT)]. Research modalities include various light microscopy techniques (confocal, multiphoton, total internal reflection, superresolution fluorescence microscopy), electron microscopy, mass spectrometry imaging, fluorescence tomography, bioluminescence, variations of OCT, and optoacoustic imaging, among a few others. Although clinical imaging and research microscopy are often isolated from one another, we argue that their combination and integration is not only informative but also essential to discovering new biology and interpreting clinical datasets in which signals invariably originate from hundreds to thousands of cells per voxel. PMID:26598657

  3. Advanced image memory architecture

    NASA Astrophysics Data System (ADS)

    Vercillo, Richard; McNeill, Kevin M.

    1994-05-01

    A workstation for radiographic images, known as the Arizona Viewing Console (AVC), was developed at the University of Arizona Health Sciences Center in the Department of Radiology. This workstation has been in use as a research tool to aid us in investigating how a radiologist interacts with a workstation, to determine which image processing features are required to aid the radiologist, to develop user interfaces and to support psychophysical and clinical studies. Results from these studies have show a need to increase the current image memory's available storage in order to accommodate high resolution images. The current triple-ported image memory can be allocated to store any number of images up to a combined total of 4 million pixels. Over the past couple of years, higher resolution images have become easier to generate with the advent of laser digitizers and computed radiology systems. As part of our research, a larger 32 million pixel image memory for AVC has been designed to replace the existing image memory.

  4. Wide field imaging of solar system objects with an 8192 x 8192 CCD mosaic

    NASA Technical Reports Server (NTRS)

    Hall, Donald N. B.

    1995-01-01

    As part of this program, we successfully completed the construction of the world's largest CCD camera, an 8192 x 8192 CCD mosaic. The system employs 8 2K x 4K 3-edge buttable CCDs arranged in a 2 x 4 chip mosaic. The focal plane has small gaps (less than 1 mm) between mosaic elements and measures over 120 mm x 120 mm. The initial set of frontside illuminated CCDs were developed with Loral-Fairchild in a custom foundry run. The initial lots yielded of order 20 to 25 functional devices, of which we selected the best eight for inclusion for the camera. We have designed a custom 3-edge-buttable package that ensures the CCD dies are mounted flat to plus or minus 10 microns over the entire area of the mosaic. The mosaic camera system consists of eight separate readout signal chains controlled by two independent DSP microcontrollers. These are in turn interfaced to a Sun Sparc-10 workstation through two high speed fiber optic interfaces. The system saw first-light on the Canada-France-Hawaii Telescope on Mauna Kea in March 1995. First-light on the University of Hawaii 2.2-M Telescope on Mauna Kea was in July 1995. Both runs were quite successful. A sample of some of the early science from the first light run is reported in the publication, 'Observations of Weak Lensing in Clusters with an 8192 x 8192 CCD Mosaic Camera'.

  5. Wetland resource investigation of the northern suburb of the Zhangye City based on the airborne CCD images

    NASA Astrophysics Data System (ADS)

    Ma, Mingguo

    2009-10-01

    The CCD images were obtained during the intensive observation period of the Watershed Allied Telemetry Experimental Research. 49 scenes of CCD images with 1-m spatial resolution were used for the pre-processed and investigation on the north suburban wetland resource for the Zhangye City. The pre-processing includes radiometric correction, preliminary geometric correction, preliminary image mosaicing, offset position processing, color matching, differential GPS measurement of the Ground Control Points, geometric precision correction. The image mosaicing exists a series of problems. The biggest problem is the disagreement of the hues. The software of Geoway ColorPro was used to match the colors. The manual interpretation method was applied to extract the patch boundary and type from the mosaiced image. Some questionably patch types were confirmed based on the field investigation. Three main conclusions can be obtained according to the investigation. Firstly, the wetland patches are more fragmentized than the patches of the other land use types. Secondly, the wetland area occupies 45.8 percentages of the total investigation area. The first three wetland types are herb swamp, forest and shrub, and Inland salt marsh. Finally, the investigation results were widely applied to the different departments of the local government.

  6. Modern Imaging Technology: Recent Advances

    SciTech Connect

    Welch, Michael J.; Eckelman, William C.

    2004-06-18

    This 2-day conference is designed to bring scientist working in nuclear medicine, as well as nuclear medicine practitioners together to discuss the advances in four selected areas of imaging: Biochemical Parameters using Small Animal Imaging, Developments in Small Animal PET Imaging, Cell Labeling, and Imaging Angiogenesis Using Multiple Modality. The presentations will be on molecular imaging applications at the forefront of research, up to date on the status of molecular imaging in nuclear medicine as well as in related imaging areas. Experts will discuss the basic science of imaging techniques, and scheduled participants will engage in an exciting program that emphasizes the current status of molecular imaging as well as the role of DOE funded research in this area.

  7. Mammographic imaging with a small format CCD-based digital cassette: Physical characteristics of a clinical systema

    PubMed Central

    Vedantham, Srinivasan; Karellas, Andrew; Suryanarayanan, Sankararaman; Levis, Ilias; Sayag, Michel; Kleehammer, Robert; Heidsieck, Robert; D’Orsi, Carl J.

    2008-01-01

    The physical characteristics of a clinical charge coupled device (CCD)-based imager (Senovision, GE Medical Systems, Milwaukee, WI) for small-field digital mammography have been investigated. The imager employs a MinR 2000™ (Eastman Kodak Company, Rochester, NY) scintillator coupled by a 1:1 optical fiber to a front-illuminated 61×61 mm CCD operating at a pixel pitch of 30 microns. Objective criteria such as modulation transfer function (MTF), noise power spectrum (NPS), detective quantum efficiency (DQE), and noise equivalent quanta (NEQ) were employed for this evaluation. The results demonstrated a limiting spatial resolution (10% MTF) of 10 cy/mm. The measured DQE of the current prototype utilizing a 28 kVp, Mo–Mo spectrum beam hardened with 4.5 cm Lucite is ~40% at close to zero spatial frequency at an exposure of 8.2 mR, and decreases to ~28% at a low exposure of 1.1 mR. Detector element nonuniformity and electronic gain variations were not significant after appropriate calibration and software corrections. The response of the imager was linear and did not exhibit signal saturation under tested exposure conditions. PMID:10984230

  8. Observations of the plasma torus of Jupiter with a Fabry-Perot/charge-coupled device /CCD/ imaging spectrometer

    NASA Technical Reports Server (NTRS)

    Roesler, F. L.; Scherb, F.; Oliversen, R.; Jaehnig, K.; Williams, T.; York, D. G.; Jenkins, E. B.

    1981-01-01

    A description is presented of the use of a CCD imaging spectrometer which has been employed at a 2.1 m telescope to obtain monochromatic images in the red and near infrared. The system studied was Jupiter's plasma torus which circles the planet with radial extent about 5 RJ and 7 RJ (RJ is the radius of Jupiter). In ground based measurements the torus has been observed in the forbidden emission lines of S(plus) at 6716 A and 6731 A and S(plus plus) at 9531 A. Attention is given to aspects of instrumentation, observations, and performance. It is felt that the particular significance of the obtained results from the instrumental point of view is the demonstration that the CCD is an excellent detector for monochromatic imaging in the near infrared out to at least 10830 A and that pixel binning before readout can produce significantly improved S/N ratios for the study of faint, diffuse sources in cases where readout noise is dominant.

  9. Effect of direct x-ray interaction in the photodetector on image noise for a CCD/scintillator system

    NASA Astrophysics Data System (ADS)

    Flynn, Michael J.; Hames, Sean M.; Ciarelli, James J.

    1996-04-01

    Digital x-ray imaging detectors for soft x-rays (1 to 50 keV) are significant for medical mammography, dental radiography, microradiography, x-ray diffraction, and x-ray telescope applications. For systems in which a scintillator is optically coupled to a photodetector, a small number of electrons are produced for each interaction in the scintillator (more than 10 e- in well designed systems). However, x-rays interacting directly in the photodetector produce a large charge for each detected event (about 4,700 e- for a 17 keV x-ray absorbed in silicon. These direct interactions can significantly increase image noise even when their interaction probability and contribution to image signal are low. In this paper we report on analytic investigations of the direct and indirect contributions to noise for a system consisting of a CsI scintillator, fiber optic coupler, and CCD photo-detector. The fiber optic coupler is shown to be essential to shield the CCD detector from direct interactions. A 3 mm thick fiber optic coupler is sufficient to eliminate most of the events that can noticeably increase noise.

  10. Laboratory simulation of Euclid-like sky images to study the impact of CCD radiation damage on weak gravitational lensing

    NASA Astrophysics Data System (ADS)

    Prod'homme, T.; Verhoeve, P.; Oosterbroek, T.; Boudin, N.; Short, A.; Kohley, R.

    2014-07-01

    Euclid is the ESA mission to map the geometry of the dark universe. It uses weak gravitational lensing, which requires the accurate measurement of galaxy shapes over a large area in the sky. Radiation damage in the 36 Charge-Coupled Devices (CCDs) composing the Euclid visible imager focal plane has already been identified as a major contributor to the weak-lensing error budget; radiation-induced charge transfer inefficiency (CTI) distorts the galaxy images and introduces a bias in the galaxy shape measurement. We designed a laboratory experiment to project Euclid-like sky images onto an irradiated Euclid CCD. In this way - and for the first time - we are able to directly assess the effect of CTI on the Euclid weak-lensing measurement free of modelling uncertainties. We present here the experiment concept, setup, and first results. The results of such an experiment provide test data critical to refine models, design and test the Euclid data processing CTI mitigation scheme, and further optimize the Euclid CCD operation.

  11. Imaging the Moon II: Webcam CCD Observations and Analysis (a Two-Week Lab for Non-Majors)

    NASA Astrophysics Data System (ADS)

    Sato, T.

    2014-07-01

    Imaging the Moon is a successful two-week lab involving real sky observations of the Moon in which students make telescopic observations and analyze their own images. Originally developed around the 35 mm film camera, a common household object adapted for astronomical work, the lab now uses webcams as film photography has evolved into an obscure specialty technology and increasing numbers of students have little familiarity with it. The printed circuit board with the CCD is harvested from a commercial webcam and affixed to a tube to mount on a telescope in place of an eyepiece. Image frames are compiled to form a lunar mosaic, and crater sizes are measured. Students also work through the logistical steps of telescope time assignment and scheduling. They learn to keep a schedule and work with uncertainties of weather in ways paralleling research observations. Because there is no need for a campus observatory, this lab can be replicated at a wide variety of institutions.

  12. Infrared imaging spectrometry by the use of bundled chalcogenide glass fibers and a PtSi CCD camera

    NASA Astrophysics Data System (ADS)

    Saito, Mitsunori; Kikuchi, Katsuhiro; Tanaka, Chinari; Sone, Hiroshi; Morimoto, Shozo; Yamashita, Toshiharu T.; Nishii, Junji

    1999-10-01

    A coherent fiber bundle for infrared image transmission was prepared by arranging 8400 chalcogenide (AsS) glass fibers. The fiber bundle, 1 m in length, is transmissive in the infrared spectral region of 1 - 6 micrometer. A remote spectroscopic imaging system was constructed with the fiber bundle and an infrared PtSi CCD camera. The system was used for the real-time observation (frame time: 1/60 s) of gas distribution. Infrared light from a SiC heater was delivered to a gas cell through a chalcogenide fiber, and transmitted light was observed through the fiber bundle. A band-pass filter was used for the selection of gas species. A He-Ne laser of 3.4 micrometer wavelength was also used for the observation of hydrocarbon gases. Gases bursting from a nozzle were observed successfully by a remote imaging system.

  13. Advanced Land Imager Assessment System

    NASA Technical Reports Server (NTRS)

    Chander, Gyanesh; Choate, Mike; Christopherson, Jon; Hollaren, Doug; Morfitt, Ron; Nelson, Jim; Nelson, Shar; Storey, James; Helder, Dennis; Ruggles, Tim; Kaita, Ed; Levy, Raviv; Ong, Lawrence; Markham, Brian; Schweiss, Robert

    2008-01-01

    The Advanced Land Imager Assessment System (ALIAS) supports radiometric and geometric image processing for the Advanced Land Imager (ALI) instrument onboard NASA s Earth Observing-1 (EO-1) satellite. ALIAS consists of two processing subsystems for radiometric and geometric processing of the ALI s multispectral imagery. The radiometric processing subsystem characterizes and corrects, where possible, radiometric qualities including: coherent, impulse; and random noise; signal-to-noise ratios (SNRs); detector operability; gain; bias; saturation levels; striping and banding; and the stability of detector performance. The geometric processing subsystem and analysis capabilities support sensor alignment calibrations, sensor chip assembly (SCA)-to-SCA alignments and band-to-band alignment; and perform geodetic accuracy assessments, modulation transfer function (MTF) characterizations, and image-to-image characterizations. ALIAS also characterizes and corrects band-toband registration, and performs systematic precision and terrain correction of ALI images. This system can geometrically correct, and automatically mosaic, the SCA image strips into a seamless, map-projected image. This system provides a large database, which enables bulk trending for all ALI image data and significant instrument telemetry. Bulk trending consists of two functions: Housekeeping Processing and Bulk Radiometric Processing. The Housekeeping function pulls telemetry and temperature information from the instrument housekeeping files and writes this information to a database for trending. The Bulk Radiometric Processing function writes statistical information from the dark data acquired before and after the Earth imagery and the lamp data to the database for trending. This allows for multi-scene statistical analyses.

  14. Retrieve leaf area index from HJ-CCD image based on support vector regression and physical model

    NASA Astrophysics Data System (ADS)

    Pan, Jingjing; Yang, Hua; He, Wei; Xu, Peipei

    2013-10-01

    Many vegetation biophysical parameters, e.g. Leaf Area Index, have nonlinear relationships with spectral reflectance, while Support Vector Regression (SVR) has fantastic nonlinear fitting ability owing to kernel inner product and the sparseness of Support Vectors (SVs). Currently, most of the LAI inversion methods over Huanjing optical satellites (HJ) are based on empirical relationship between LAI and spectral index, which have some limitations. In this paper, we developed an algorithm combining SVR and physical model-PROSAIL to retrieve LAI over HJ-CCD image. The model adopted a new HJ vegetation index (HJVI), which can lessen saturation on high LAI domain. Experiments over simulations generated by PROSAIL model proved the new algorithm's good performance on noising resisting and effectiveness of HJVI. Finally, we applied the algorithm on a HJ1B CCD2 image and validated it with the field measured data in Xinxiang, Henan Province, China. The RMSE of 0.5230 indicated the applicability of the SVR-based physical method over HJ data.

  15. Design and implementation of fast bipolar clock drivers for CCD imaging systems in space applications

    NASA Astrophysics Data System (ADS)

    Jayarajan, Jayesh; Kumar, Nishant; Verma, Amarnath; Thaker, Ramkrishna

    2016-05-01

    Drive electronics for generating fast, bipolar clocks, which can drive capacitive loads of the order of 5-10nF are indispensable for present day Charge Coupled Devices (CCDs). Design of these high speed bipolar clocks is challenging because of the capacitive loads that have to be driven and a strict constraint on the rise and fall times. Designing drive electronics circuits for space applications becomes even more challenging due to limited number of available discrete devices, which can survive in the harsh radiation prone space environment. This paper presents the design, simulations and test results of a set of such high speed, bipolar clock drivers. The design has been tested under a thermal cycle of -15 deg C to +55 deg C under vacuum conditions and has been designed using radiation hardened components. The test results show that the design meets the stringent rise/fall time requirements of 50+/-10ns for Multiple Vertical CCD (VCCD) clocks and 20+/-5ns for Horizontal CCD (HCCD) clocks with sufficient design margins across full temperature range, with a pixel readout rate of 6.6MHz. The full design has been realized in flexi-rigid PCB with package volume of 140x160x50 mm3.

  16. CCD and CMOS sensors

    NASA Astrophysics Data System (ADS)

    Waltham, Nick

    The charge-coupled device (CCD) has been developed primarily as a compact image sensor for consumer and industrial markets, but is now also the preeminent visible and ultraviolet wavelength image sensor in many fields of scientific research including space-science and both Earth and planetary remote sensing. Today"s scientific or science-grade CCD will strive to maximise pixel count, focal plane coverage, photon detection efficiency over the broadest spectral range and signal dynamic range whilst maintaining the lowest possible readout noise. The relatively recent emergence of complementary metal oxide semiconductor (CMOS) image sensor technology is arguably the most important development in solid-state imaging since the invention of the CCD. CMOS technology enables the integration on a single silicon chip of a large array of photodiode pixels alongside all of the ancillary electronics needed to address the array and digitise the resulting analogue video signal. Compared to the CCD, CMOS promises a more compact, lower mass, lower power and potentially more radiation tolerant camera.

  17. Recent imaging advances in neurology.

    PubMed

    Rocchi, Lorenzo; Niccolini, Flavia; Politis, Marios

    2015-09-01

    Over the recent years, the application of neuroimaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) has considerably advanced the understanding of complex neurological disorders. PET is a powerful molecular imaging tool, which investigates the distribution and binding of radiochemicals attached to biologically relevant molecules; as such, this technique is able to give information on biochemistry and metabolism of the brain in health and disease. MRI uses high intensity magnetic fields and radiofrequency pulses to provide structural and functional information on tissues and organs in intact or diseased individuals, including the evaluation of white matter integrity, grey matter thickness and brain perfusion. The aim of this article is to review the most recent advances in neuroimaging research in common neurological disorders such as movement disorders, dementia, epilepsy, traumatic brain injury and multiple sclerosis, and to evaluate their contribution in the diagnosis and management of patients. PMID:25808503

  18. Scientific CCD technology at JPL

    NASA Technical Reports Server (NTRS)

    Janesick, J.; Collins, S. A.; Fossum, E. R.

    1991-01-01

    Charge-coupled devices (CCD's) were recognized for their potential as an imaging technology almost immediately following their conception in 1970. Twenty years later, they are firmly established as the technology of choice for visible imaging. While consumer applications of CCD's, especially the emerging home video camera market, dominated manufacturing activity, the scientific market for CCD imagers has become significant. Activity of the Jet Propulsion Laboratory and its industrial partners in the area of CCD imagers for space scientific instruments is described. Requirements for scientific imagers are significantly different from those needed for home video cameras, and are described. An imager for an instrument on the CRAF/Cassini mission is described in detail to highlight achieved levels of performance.

  19. Advances in multimodality molecular imaging

    PubMed Central

    Zaidi, Habib; Prasad, Rameshwar

    2009-01-01

    Multimodality molecular imaging using high resolution positron emission tomography (PET) combined with other modalities is now playing a pivotal role in basic and clinical research. The introduction of combined PET/CT systems in clinical setting has revolutionized the practice of diagnostic imaging. The complementarity between the intrinsically aligned anatomic (CT) and functional or metabolic (PET) information provided in a “one-stop shop” and the possibility to use CT images for attenuation correction of the PET data has been the driving force behind the success of this technology. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) in a single gantry is technically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of few preclinical PET systems and one human prototype dedicated for simultaneous PET/MR brain imaging. This paper discusses recent advances in PET instrumentation and the advantages and challenges of multimodality imaging systems. Future opportunities and the challenges facing the adoption of multimodality imaging instrumentation will also be addressed. PMID:20098557

  20. Design of a hardware/software FPGA-based driver system for a large area high resolution CCD image sensor

    NASA Astrophysics Data System (ADS)

    Chen, Ying; Xu, Wanpeng; Zhao, Rongsheng; Chen, Xiangning

    2014-09-01

    A hardware/software field programmable gate array (FPGA)-based driver system was proposed and demonstrated for the KAF-39000 large area high resolution charge coupled device (CCD). The requirements of the KAF-39000 driver system were analyzed. The structure of "microprocessor with application specific integrated circuit (ASIC) chips" was implemented to design the driver system. The system test results showed that dual channels of imaging analog data were obtained with a frame rate of 0.87 frame/s. The frequencies of horizontal timing and vertical timing were 22.9 MHz and 28.7 kHz, respectively, which almost reached the theoretical value of 24 MHz and 30 kHz, respectively.

  1. Statistical analysis of temporal and spatial evolution of in-vessel dust particles in fusion devices by using CCD images

    NASA Astrophysics Data System (ADS)

    Hong, Suk-Ho; Kim, Kyung-Rae; Nam, Yong-Un; Chung, Jinil; Grisolia, Christian; Rohde, Volker; KSTAR Team; TORE SUPRA Team; ASDEX Upgrade Team

    2013-08-01

    Images of wide-angle visible standard CCD cameras contain information on Dust Creation Events (DCEs) that occur during plasma operations. Database on the DCEs can be built by analyzing the straight line-like dust trajectories in scrape-off layer caused by plasma-dust interaction along the vacuum vessel. The database provides short/long term temporal evolution and spatial distribution of origins of DCEs in fusion devices. We have studied DCEs of 2011 KSTAR campaign and compared with that of 2006 Tore Supra (TS) and 2007 ASDEX Upgrade (AUG) campaign. An analysis software, with which the location of dust trajectories in 3D position in the KSTAR vacuum vessel is identified, is developed and the dust velocity distribution in 2011 campaign is measured. ©2001 Elsevier Science.

  2. Electronic intraoral dental x-ray imaging system employing a direct-sensing CCD array

    NASA Astrophysics Data System (ADS)

    Cox, John D.; Langford, D. S.; Williams, Donald W.

    1993-12-01

    A commercial prototype intraoral radiography system has been developed that can provide digital x-ray images for diagnosis. The system consists of an intraoral detector head, an intermediate drive electronics package, a main drive electronics package, and a PC-based digital image management system. The system has the potential to replace the use of dental film in intraoral radiographic examinations. High-resolution images are acquired, then displayed on a CRT within seconds of image acquisition.

  3. Visual enhancement of laparoscopic nephrectomies using the 3-CCD camera

    NASA Astrophysics Data System (ADS)

    Crane, Nicole J.; Kansal, Neil S.; Dhanani, Nadeem; Alemozaffar, Mehrdad; Kirk, Allan D.; Pinto, Peter A.; Elster, Eric A.; Huffman, Scott W.; Levin, Ira W.

    2006-02-01

    Many surgical techniques are currently shifting from the more conventional, open approach towards minimally invasive laparoscopic procedures. Laparoscopy results in smaller incisions, potentially leading to less postoperative pain and more rapid recoveries . One key disadvantage of laparoscopic surgery is the loss of three-dimensional assessment of organs and tissue perfusion. Advances in laparoscopic technology include high-definition monitors for improved visualization and upgraded single charge coupled device (CCD) detectors to 3-CCD cameras, to provide a larger, more sensitive color palette to increase the perception of detail. In this discussion, we further advance existing laparoscopic technology to create greater enhancement of images obtained during radical and partial nephrectomies in which the assessment of tissue perfusion is crucial but limited with current 3-CCD cameras. By separating the signals received by each CCD in the 3-CCD camera and by introducing a straight forward algorithm, rapid differentiation of renal vessels and perfusion is accomplished and could be performed real time. The newly acquired images are overlaid onto conventional images for reference and comparison. This affords the surgeon the ability to accurately detect changes in tissue oxygenation despite inherent limitations of the visible light image. Such additional capability should impact procedures in which visual assessment of organ vitality is critical.

  4. Photon counting imaging with an electron-bombarded CCD: Towards a parallel-processing photoelectronic time-to-amplitude converter

    SciTech Connect

    Hirvonen, Liisa M.; Jiggins, Stephen; Sergent, Nicolas; Zanda, Gianmarco; Suhling, Klaus

    2014-12-15

    We have used an electron-bombarded CCD for optical photon counting imaging. The photon event pulse height distribution was found to be linearly dependent on the gain voltage. We propose on this basis that a gain voltage sweep during exposure in an electron-bombarded sensor would allow photon arrival time determination with sub-frame exposure time resolution. This effectively uses an electron-bombarded sensor as a parallel-processing photoelectronic time-to-amplitude converter, or a two-dimensional photon counting streak camera. Several applications that require timing of photon arrival, including Fluorescence Lifetime Imaging Microscopy, may benefit from such an approach. A simulation of a voltage sweep performed with experimental data collected with different acceleration voltages validates the principle of this approach. Moreover, photon event centroiding was performed and a hybrid 50% Gaussian/Centre of Gravity + 50% Hyperbolic cosine centroiding algorithm was found to yield the lowest fixed pattern noise. Finally, the camera was mounted on a fluorescence microscope to image F-actin filaments stained with the fluorescent dye Alexa 488 in fixed cells.

  5. Intra-Oral X-Ray Fluoroscopy With Image Intensifier And CCD. A new imagery for a new dentistry.

    NASA Astrophysics Data System (ADS)

    Le Denmat, D.; Bonifay, P.; Camus, Jean P.; Bouchier, Guy; Roville, J. C.

    1989-05-01

    At present, many dental acts involve operations carried out without visual monitoring, for example in mouth surgery or during the course of a dental root canal treatment. While this kind of operation is in progress, the dental surgeon is guided by his tactile sense alone. Only the traditional pre and post-operative radiographic examinations are possible. Waiting for a least ten minutes is the time required for these radiographs. This article describes a new material giving the dentist the means of a real time visual monitoring for the intervention being carried out. The device implemented in our laboratory is a dental fluoroscopy set with low level X-ray doses, small field, suitable resolution, and primarily usable for kinetic images acquisition. This dental fluoroscopic device consists of : - a special X-ray generator (low exposure and collimated flow), - a fiber optics bundle and its X-ray / visible converter, - an image intensifier associated to a charge coupled device (CCD), - and finally, a digital processing device for image treatment and display. A preliminary/ dosimetric study completes this work.

  6. Low cost referenced luminescent imaging of oxygen and pH with a 2-CCD colour near infrared camera.

    PubMed

    Ehgartner, Josef; Wiltsche, Helmar; Borisov, Sergey M; Mayr, Torsten

    2014-10-01

    A low cost imaging set-up for optical chemical sensors based on NIR-emitting dyes is presented. It is based on a commercially available 2-CCD colour near infrared camera, LEDs and tailor-made optical sensing materials for oxygen and pH. The set-up extends common ratiometric RGB imaging based on the red, green and blue channels of colour cameras by an additional NIR channel. The hardware and software of the camera were adapted to perform ratiometric imaging. A series of new planar sensing foils were introduced to image oxygen, pH and both parameters simultaneously. The used NIR-emitting indicators are based on benzoporphyrins and aza-BODIPYs for oxygen and pH, respectively. Moreover, a wide dynamic range oxygen sensor is presented. It allows accurate imaging of oxygen from trace levels up to ambient air concentrations. The imaging set-up in combination with the normal range ratiometric oxygen sensor showed a resolution of 4-5 hPa at low oxygen concentrations (<50 hPa) and 10-15 hPa at ambient air oxygen concentrations; the trace range oxygen sensor (<20 hPa) revealed a resolution of about 0.5-1.8 hPa. The working range of the pH-sensor was in the physiological region from pH 6.0 up to pH 8.0 and showed an apparent pKa-value of 7.3 with a resolution of about 0.1 pH units. The performance of the dual parameter oxygen/pH sensor was comparable to the single analyte pH and normal range oxygen sensors. PMID:25096329

  7. Dynamic imaging with a triggered and intensified CCD camera system in a high-intensity neutron beam

    NASA Astrophysics Data System (ADS)

    Vontobel, P.; Frei, G.; Brunner, J.; Gildemeister, A. E.; Engelhardt, M.

    2005-04-01

    When time-dependent processes within metallic structures should be inspected and visualized, neutrons are well suited due to their high penetration through Al, Ag, Ti or even steel. Then it becomes possible to inspect the propagation, distribution and evaporation of organic liquids as lubricants, fuel or water. The principle set-up of a suited real-time system was implemented and tested at the radiography facility NEUTRA of PSI. The highest beam intensity there is 2×107 cm s, which enables to observe sequences in a reasonable time and quality. The heart of the detection system is the MCP intensified CCD camera PI-Max with a Peltier cooled chip (1300×1340 pixels). The intensifier was used for both gating and image enhancement, where as the information was accumulated over many single frames on the chip before readout. Although, a 16-bit dynamic range is advertised by the camera manufacturers, it must be less due to the inherent noise level from the intensifier. The obtained result should be seen as the starting point to go ahead to fit the different requirements of car producers in respect to fuel injection, lubricant distribution, mechanical stability and operation control. Similar inspections will be possible for all devices with repetitive operation principle. Here, we report about two measurements dealing with the lubricant distribution in a running motorcycle motor turning at 1200 rpm. We were monitoring the periodic stationary movements of piston, valves and camshaft with a micro-channel plate intensified CCD camera system (PI-Max 1300RB, Princeton Instruments) triggered at exactly chosen time points.

  8. Back-illuminated CCD imager adapted for contrast transfer function measurements thereon

    NASA Technical Reports Server (NTRS)

    Levine, Peter A. (Inventor)

    1987-01-01

    Stripe patterns of varying spatial frequency, formed in the top-metalization of a back-illuminated solid-state imager, facilitate on-line measurement of contrast transfer function during wafer-probe testing. The imager may be packaged to allow front-illumination during in-the-field testing after its manufacture.

  9. Optical design and characterization of an advanced computational imaging system

    NASA Astrophysics Data System (ADS)

    Shepard, R. Hamilton; Fernandez-Cull, Christy; Raskar, Ramesh; Shi, Boxin; Barsi, Christopher; Zhao, Hang

    2014-09-01

    We describe an advanced computational imaging system with an optical architecture that enables simultaneous and dynamic pupil-plane and image-plane coding accommodating several task-specific applications. We assess the optical requirement trades associated with custom and commercial-off-the-shelf (COTS) optics and converge on the development of two low-cost and robust COTS testbeds. The first is a coded-aperture programmable pixel imager employing a digital micromirror device (DMD) for image plane per-pixel oversampling and spatial super-resolution experiments. The second is a simultaneous pupil-encoded and time-encoded imager employing a DMD for pupil apodization or a deformable mirror for wavefront coding experiments. These two testbeds are built to leverage two MIT Lincoln Laboratory focal plane arrays - an orthogonal transfer CCD with non-uniform pixel sampling and on-chip dithering and a digital readout integrated circuit (DROIC) with advanced on-chip per-pixel processing capabilities. This paper discusses the derivation of optical component requirements, optical design metrics, and performance analyses for the two testbeds built.

  10. Fully depleted back illuminated CCD

    DOEpatents

    Holland, Stephen Edward

    2001-01-01

    A backside illuminated charge coupled device (CCD) is formed of a relatively thick high resistivity photon sensitive silicon substrate, with frontside electronic circuitry, and an optically transparent backside ohmic contact for applying a backside voltage which is at least sufficient to substantially fully deplete the substrate. A greater bias voltage which overdepletes the substrate may also be applied. One way of applying the bias voltage to the substrate is by physically connecting the voltage source to the ohmic contact. An alternate way of applying the bias voltage to the substrate is to physically connect the voltage source to the frontside of the substrate, at a point outside the depletion region. Thus both frontside and backside contacts can be used for backside biasing to fully deplete the substrate. Also, high resistivity gaps around the CCD channels and electrically floating channel stop regions can be provided in the CCD array around the CCD channels. The CCD array forms an imaging sensor useful in astronomy.

  11. CCD-Based Imaging of Low-Energy Charged Particle Distribution Functions on ePOP and Swarm

    NASA Astrophysics Data System (ADS)

    Knudsen, D. J.; Burchill, J. K.

    2013-12-01

    The Canadian Enhanced Polar Outflow Probe (ePOP) and the European Space Agency's three Swarm satellites are being readied for launch in September and November 2013, respectively. Each will carry instruments that incorporate a novel CCD-based charged-particle detector to provide 64-pixel-diameter images of 2-D, low-energy charged particle distributions. The ePOP Suprathermal Electron Imager (SEI) will produce distribution functions in pitch angle and energy up to 200 eV at rates of up to 100 per second, with the goal of characterizing photo and suprathermal electrons that can drive ion outflow. The SEI can also image ion distributions up to 20 eV. ePOP will be launched on a Space-X Falcon 9 rocket into a polar elliptical orbit with an apogee of 1500 km. The Swarm satellites will be launched on a Russian Rokot vehicle into circular polar orbits, two at an initial altitude of 450 km, the third at 530 km. Swarm will measure magnetic and electric fields, the latter indirectly through ion drift detected by two Thermal Ion Imagers (TII) in each instrument, with the aid of Langmuir probe measurements of spacecraft potential and electron density and temperature. Electric fields measurements will be produced at a cadence of 2 per second to produce a picture of ionospheric electrodynamics at scales from 4 km to global. Due to special emphasis on measurement precision, Swarm will be able to resolve variations in Poynting flux as small as 1 microWatt per square meter. We gratefully acknowledge the ePOP SEI technical development team at the University of Calgary, and funding from the Canadian Space Agency. The Swarm Electric Field Instruments were built by a COM DEV Canada in collaboration with the University of Calgary and the Swedish Institute for Space Physics in Uppsala, with funding from ESA and CSA.

  12. High-resolution application of YAG:Ce and LuAG:Ce imaging detectors with a CCD X-ray camera

    NASA Astrophysics Data System (ADS)

    Touš, Jan; Horváth, Martin; Pína, Ladislav; Blažek, Karel; Sopko, Bruno

    2008-06-01

    A high-resolution CCD X-ray camera based on YAG:Ce or LuAG:Ce thin scintillators is presented. High-resolution in low-energy X-ray radiation is proved with several objects. The spatial resolution achieved in the images is about 1 μm. The high-resolution imaging system is a combination of a high-sensitivity digital CCD camera and an optical system with a thin scintillator-imaging screen. The screen can consist of YAG:Ce or LuAG:Ce inorganic scintillator [J.A. Mares, Radiat. Meas. 38 (2004) 353]. These materials have the advantages of mechanical and chemical stability and non-hygroscopicity. The high-resolution imaging system can be used with different types of radiation (X-ray, electrons, UV, and VUV [M. Nikl, Meas. Sci. Technol. 17 (2006) R37]). The objects used for the imaging tests are grids and small animals with features of several microns in size. The resolution capabilities were tested using different types of CCD cameras and scintillation imaging screens.

  13. Colorized linear CCD data acquisition system with automatic exposure control

    NASA Astrophysics Data System (ADS)

    Li, Xiaofan; Sui, Xiubao

    2014-11-01

    Colorized linear cameras deliver superb color fidelity at the fastest line rates in the industrial inspection. It's RGB trilinear sensor eliminates image artifacts by placing a separate row of pixels for each color on a single sensor. It's advanced design minimizes distance between rows to minimize image artifacts due to synchronization. In this paper, the high-speed colorized linear CCD data acquisition system was designed take advantages of the linear CCD sensor μpd3728. The hardware and software design of the system based on FPGA is introduced and the design of the functional modules is performed. The all system is composed of CCD driver module, data buffering module, data processing module and computer interface module. The image data was transferred to computer by Camera link interface. The system which automatically adjusts the exposure time of linear CCD, is realized with a new method. The integral time of CCD can be controlled by the program. The method can automatically adjust the integration time for different illumination intensity under controlling of FPGA, and respond quickly to brightness changes. The data acquisition system is also offering programmable gains and offsets for each color. The quality of image can be improved after calibration in FPGA. The design has high expansibility and application value. It can be used in many application situations.

  14. The Orthogonal Transfer CCD

    NASA Astrophysics Data System (ADS)

    Tonry, J.; Burke, Barry E.; Schechter, Paul L.

    1997-10-01

    We have designed and built a new type of CCD that we call an orthogonal transfer CCD (OTCCD), which permits parallel clocking horizontally as well as vertically. The device has been used successfully to remove image motion caused by atmospheric turbulence at rates up to 100 Hz, and promises to be a better, cheaper way to carry out image motion correction for imaging than by using fast tip/tilt mirrors. We report on the device characteristics, and find that the large number of transfers needed to track image motion does not significantly degrade the image either because of charge transfer inefficiency or because of charge traps. For example, after 100 sec of tracking at 100 Hz approximately 3% of the charge would diffuse into a skirt around the point spread function. Four nights of data at the Michigan-Dartmouth-MIT (MDM) 2.4-m telescope also indicate that the atmosphere is surprisingly benign, in terms of both the speed and coherence angle of image motion. Image motion compensation improved image sharpness by about 0.5'' in quadrature with no degradation over a field of at least 3 arcminutes. (SECTION: Astronomical Instrumentation)

  15. Evaluation of crop yield loss of floods based on water turbidity index with multi-temporal HJ-CCD images

    NASA Astrophysics Data System (ADS)

    Gu, Xiaohe; Xu, Peng; Wang, Lei; Wang, Xiuhui

    2015-12-01

    Paddy is one of the most important food crops in China. Due to the intensive planting in the surrounding of rivers and lakes, paddy is vulnerable to flooding stress. The research on predicting crop yield loss derived from flooding stress will help the adjustment of crop planting structure and the claims of agricultural insurance. The paper aimed to develop a method of estimating yield loss of paddy derived from flooding by multi-temporal HJ CCD images. At first, the water pixels after flooding were extracted, from which the water line (WL) of turbid water pixels was generated. Secondly, the water turbidity index (WTI) and perpendicular vegetation index (PVI) was defined and calculated. By analyzing the relation among WTI, PVI and paddy yield, the model of evaluating yield loss of flooding was developed. Based on this model, the spatial distribution of paddy yield loss derived from flooding was mapped in the study area. Results showed that the water turbidity index (WTI) could be used to monitor the sediment content of flood, which was closely related to the plant physiology and per unit area yield of paddy. The PVI was the good indicator of paddy yield with significant correlation (0.965). So the PVI could be used to estimate the per unit area yield before harvesting. The PVI and WTI had good linear relation, which could provide an effective, practical and feasible method for monitoring yield loss of waterlogged paddy.

  16. Estimation of rice phenology date using integrated HJ-1 CCD and Landsat-8 OLI vegetation indices time-series images.

    PubMed

    Wang, Jing; Huang, Jing-feng; Wang, Xiu-zhen; Jin, Meng-ting; Zhou, Zhen; Guo, Qiao-ying; Zhao, Zhe-wen; Huang, Wei-jiao; Zhang, Yao; Song, Xiao-dong

    2015-10-01

    Accurate estimation of rice phenology is of critical importance for agricultural practices and studies. However, the accuracy of phenological parameters extracted by remote sensing data cannot be guaranteed because of the influence of climate, e.g. the monsoon season, and limited available remote sensing data. In this study, we integrate the data of HJ-1 CCD and Landsat-8 operational land imager (OLI) by using the ordinary least-squares (OLS), and construct higher temporal resolution vegetation indices (VIs) time-series data to extract the phenological parameters of single-cropped rice. Two widely used VIs, namely the normalized difference vegetation index (NDVI) and 2-band enhanced vegetation index (EVI2), were adopted to minimize the influence of environmental factors and the intrinsic difference between the two sensors. Savitzky-Golay (S-G) filters were applied to construct continuous VI profiles per pixel. The results showed that, compared with NDVI, EVI2 was more stable and comparable between the two sensors. Compared with the observed phenological data of the single-cropped rice, the integrated VI time-series had a relatively low root mean square error (RMSE), and EVI2 showed higher accuracy compared with NDVI. We also demonstrate the application of phenology extraction of the single-cropped rice in a spatial scale in the study area. While the work is of general value, it can also be extrapolated to other regions where qualified remote sensing data are the bottleneck but where complementary data are occasionally available. PMID:26465131

  17. Estimation of rice phenology date using integrated HJ-1 CCD and Landsat-8 OLI vegetation indices time-series images*

    PubMed Central

    Wang, Jing; Huang, Jing-Feng; Wang, Xiu-Zhen; Jin, Meng-Ting; Zhou, Zhen; Guo, Qiao-Ying; Zhao, Zhe-Wen; Huang, Wei-Jiao; Zhang, Yao; Song, Xiao-Dong

    2015-01-01

    Accurate estimation of rice phenology is of critical importance for agricultural practices and studies. However, the accuracy of phenological parameters extracted by remote sensing data cannot be guaranteed because of the influence of climate, e.g. the monsoon season, and limited available remote sensing data. In this study, we integrate the data of HJ-1 CCD and Landsat-8 operational land imager (OLI) by using the ordinary least-squares (OLS), and construct higher temporal resolution vegetation indices (VIs) time-series data to extract the phenological parameters of single-cropped rice. Two widely used VIs, namely the normalized difference vegetation index (NDVI) and 2-band enhanced vegetation index (EVI2), were adopted to minimize the influence of environmental factors and the intrinsic difference between the two sensors. Savitzky-Golay (S-G) filters were applied to construct continuous VI profiles per pixel. The results showed that, compared with NDVI, EVI2 was more stable and comparable between the two sensors. Compared with the observed phenological data of the single-cropped rice, the integrated VI time-series had a relatively low root mean square error (RMSE), and EVI2 showed higher accuracy compared with NDVI. We also demonstrate the application of phenology extraction of the single-cropped rice in a spatial scale in the study area. While the work is of general value, it can also be extrapolated to other regions where qualified remote sensing data are the bottleneck but where complementary data are occasionally available. PMID:26465131

  18. Analysis of CCD images of the coma of comet P/Halley

    NASA Technical Reports Server (NTRS)

    Combi, Michael R.

    1992-01-01

    The modeling analysis objective of this project is to make use of the skill acquired in the development of Monte Carlo particle trajectory models for the distributions of gas species in cometary comae as a basis for a new dust coma model. This model will include a self-consistent picture of the time-dependent dusty-gas dynamics of the inner coma and the three-dimensional time-dependent trajectories of the dust particles under the influence of solar gravity and solar radiation pressure in the outer coma. Our purpose is to use this model as a tool to analyze selected images from two sets of data of the comet P/Halley with the hope that we can help to understand the effects of a number of important processes on the spatial morphology of the observed dust coma. The study will proceed much in the same way as our study of the spatially extended hydrogen coma where we were able to understand the spatial morphology of the Lyman-alpha coma in terms of the partial thermalization of the hot H atoms produced by the photodissociation of cometary H2O and OH. The processes of importance to the observed dust coma include: (1) the dust particle size distribution function; (2) the terminal velocities of various sized dust particles in the inner coma; (3) the radiation scattering properties of dust particles, which are important both in terms of the observed scattered radiation and the radiation pressure acceleration on dust particles; (4) the fragmentation and/or vaporization of dust particles; (5) the relative importance of CHON and silicate dust particles as they contribute both to the dusty-gas dynamics in the inner coma (that produce the dust particle terminal velocities) and to the observed spatial morphology of the outer dust coma; and (6) the time and direction dependence of the source of dust.

  19. Recent advances in imaging technologies in dentistry

    PubMed Central

    Shah, Naseem; Bansal, Nikhil; Logani, Ajay

    2014-01-01

    Dentistry has witnessed tremendous advances in all its branches over the past three decades. With these advances, the need for more precise diagnostic tools, specially imaging methods, have become mandatory. From the simple intra-oral periapical X-rays, advanced imaging techniques like computed tomography, cone beam computed tomography, magnetic resonance imaging and ultrasound have also found place in modern dentistry. Changing from analogue to digital radiography has not only made the process simpler and faster but also made image storage, manipulation (brightness/contrast, image cropping, etc.) and retrieval easier. The three-dimensional imaging has made the complex cranio-facial structures more accessible for examination and early and accurate diagnosis of deep seated lesions. This paper is to review current advances in imaging technology and their uses in different disciplines of dentistry. PMID:25349663

  20. Streak Camera Performance with Large-Format CCD Readout

    SciTech Connect

    Lerche, R A; Andrews, D S; Bell, P M; Griffith, R L; McDonald, J W; Torres, P III; Vergel de Dios, G

    2003-07-08

    The ICF program at Livermore has a large inventory of optical streak cameras that were built in the 1970s and 1980s. The cameras include micro-channel plate image-intensifier tubes (IIT) that provide signal amplification and early lens-coupled CCD readouts. Today, these cameras are still very functional, but some replacement parts such as the original streak tube, CCD, and IIT are scarce and obsolete. This article describes recent efforts to improve the performance of these cameras using today's advanced CCD readout technologies. Very sensitive, large-format CCD arrays with efficient fiber-optic input faceplates are now available for direct coupling with the streak tube. Measurements of camera performance characteristics including linearity, spatial and temporal resolution, line-spread function, contrast transfer ratio (CTR), and dynamic range have been made for several different camera configurations: CCD coupled directly to the streak tube, CCD directly coupled to the IIT, and the original configuration with a smaller CCD lens coupled to the IIT output. Spatial resolution (limiting visual) with and without the IIT is 8 and 20 lp/mm, respectively, for photocathode current density up to 25% of the Child-Langmuir (C-L) space-charge limit. Temporal resolution (fwhm) deteriorates by about 20% when the cathode current density reaches 10% of the C-L space charge limit. Streak tube operation with large average tube current was observed by illuminating the entire slit region through a Ronchi ruling and measuring the CTR. Sensitivity (CCD electrons per streak tube photoelectron) for the various configurations ranged from 7.5 to 2,700 with read noise of 7.5 to 10.5 electrons. Optimum spatial resolution is achieved when the IIT is removed. Maximum dynamic range requires a configuration where a single photoelectron from the photocathode produces a signal that is 3 to 5 times the read noise.

  1. Design and application of TEC controller Using in CCD camera

    NASA Astrophysics Data System (ADS)

    Gan, Yu-quan; Ge, Wei; Qiao, Wei-dong; Lu, Di; Lv, Juan

    2011-08-01

    Thermoelectric cooler (TEC) is a kind of solid hot pump performed with Peltier effect. And it is small, light and noiseless. The cooling quantity is proportional to the TEC working current when the temperature difference between the hot side and the cold side keeps stable. The heating quantity and cooling quantity can be controlled by changing the value and direction of current of two sides of TEC. So, thermoelectric cooling technology is the best way to cool CCD device. The E2V's scientific image sensor CCD47-20 integrates TEC and CCD together. This package makes easier of electrical design. Software and hardware system of TEC controller are designed with CCD47-20 which is packaged with integral solid-state Peltier cooler. For hardware system, 80C51 MCU is used as CPU, 8-bit ADC and 8-bit DAC compose of closed-loop controlled system. Controlled quantity can be computed by sampling the temperature from thermistor in CCD. TEC is drove by MOSFET which consists of constant current driving circuit. For software system, advanced controlled precision and convergence speed of TEC system can be gotten by using PID controlled algorithm and tuning proportional, integral and differential coefficient. The result shows: if the heat emission of the hot side of TEC is good enough to keep the temperature stable, and when the sampling frequency is 2 seconds, temperature controlled velocity is 5°C/min. And temperature difference can reach -40°C controlled precision can achieve 0.3°C. When the hot side temperature is stable at °C, CCD temperature can reach -°C, and thermal noise of CCD is less than 1e-/pix/s. The controlled system restricts the dark-current noise of CCD and increases SNR of the camera system.

  2. CCD detectors for spectroscopy and imaging of x-rays with the eROSITA space telescope

    NASA Astrophysics Data System (ADS)

    Meidinger, N.; Andritschke, R.; Ebermayer, S.; Elbs, J.; Hälker, O.; Hartmann, R.; Herrmann, S.; Kimmel, N.; Predehl, P.; Schächner, G.; Soltau, H.; Strüder, L.; Tiedemann, L.

    2009-08-01

    A special type of CCD, the so-called PNCCD, was originally developed for the focal plane camera of the XMMNewton space telescope. After the satellite launch in 1999, the MPI Halbleiterlabor continued the detector development for various ground-based applications. Finally, a new X-ray PNCCD was designed again for a space telescope named eROSITA. The space telescope will be equipped with an array of seven parallel oriented X-ray mirror systems of Wolter-I type and seven cameras, placed in their foci. This instrumentation will permit the exploration of the X-ray universe in the energy band from 0.3 keV up to 10 keV with a time resolution of 50 ms for a full image comprising 384 x 384 pixels. eROSITA will be accommodated on the new Russian Spectrum-RG satellite. The mission was already approved by the responsible German and Russian space agencies. The detector development is focussed to fulfil the scientific specifications for detector performance under the constraints of all the mechanical, power, thermal and radiation hardness issues for space instrumentation. This considers also the recent change of the satellite's orbit. The Lagrange point L2 was decided as new destination of the satellite instead of a low-Earth orbit (LEO). We present a detailed description of the detector system and the current development status. The most recent test results are reported here. Essential steps for completion of the seven focal plane detectors until satellite launch in 2012 will be itemized.

  3. Performance evaluation of CCD- and mobile-phone-based near-infrared fluorescence imaging systems with molded and 3D-printed phantoms

    NASA Astrophysics Data System (ADS)

    Wang, Bohan; Ghassemi, Pejhman; Wang, Jianting; Wang, Quanzeng; Chen, Yu; Pfefer, Joshua

    2016-03-01

    Increasing numbers of devices are emerging which involve biophotonic imaging on a mobile platform. Therefore, effective test methods are needed to ensure that these devices provide a high level of image quality. We have developed novel phantoms for performance assessment of near infrared fluorescence (NIRF) imaging devices. Resin molding and 3D printing techniques were applied for phantom fabrication. Comparisons between two imaging approaches - a CCD-based scientific camera and an NIR-enabled mobile phone - were made based on evaluation of the contrast transfer function and penetration depth. Optical properties of the phantoms were evaluated, including absorption and scattering spectra and fluorescence excitation-emission matrices. The potential viability of contrastenhanced biological NIRF imaging with a mobile phone is demonstrated, and color-channel-specific variations in image quality are documented. Our results provide evidence of the utility of novel phantom-based test methods for quantifying image quality in emerging NIRF devices.

  4. Quantitative estimation of Secchi disk depth using the HJ-1B CCD image and in situ observations in Sishili Bay, China

    NASA Astrophysics Data System (ADS)

    Yu, Dingfeng; Zhou, Bin; Fan, Yanguo; Li, Tantan; Liang, Shouzhen; Sun, Xiaoling

    2014-11-01

    Secchi disk depth (SDD) is an important optical property of water related to water quality and primary production. The traditional sampling method is not only time-consuming and labor-intensive but also limited in terms of temporal and spatial coverage, while remote sensing technology can deal with these limitations. In this study, models estimating SDD have been proposed based on the regression analysis between the HJ-1 satellite CCD image and synchronous in situ water quality measurements. The results illustrate the band ratio model of B3/B1 of CCD could be used to estimate Secchi depth in this region, with the mean relative error (MRE) of 8.6% and root mean square error (RMSE) of 0.1 m, respectively. This model has been applied to one image of HJ-1 satellite CCD, generating water transparency on June 23, 2009, which will be of immense value for environmental monitoring. In addition, SDD was deeper in offshore waters than in inshore waters. River runoffs, hydrodynamic environments, and marine aquaculture are the main factors influencing SDD in this area.

  5. Recent Advancements in Microwave Imaging Plasma Diagnostics

    SciTech Connect

    H. Park; C.C. Chang; B.H. Deng; C.W. Domier; A.J.H. Donni; K. Kawahata; C. Liang; X.P. Liang; H.J. Lu; N.C. Luhmann, Jr.; A. Mase; H. Matsuura; E. Mazzucato; A. Miura; K. Mizuno; T. Munsat; K. and Y. Nagayama; M.J. van de Pol; J. Wang; Z.G. Xia; W-K. Zhang

    2002-03-26

    Significant advances in microwave and millimeter wave technology over the past decade have enabled the development of a new generation of imaging diagnostics for current and envisioned magnetic fusion devices. Prominent among these are revolutionary microwave electron cyclotron emission imaging (ECEI), microwave phase imaging interferometers, imaging microwave scattering and microwave imaging reflectometer (MIR) systems for imaging electron temperature and electron density fluctuations (both turbulent and coherent) and profiles (including transport barriers) on toroidal devices such as tokamaks, spherical tori, and stellarators. The diagnostic technology is reviewed, and typical diagnostic systems are analyzed. Representative experimental results obtained with these novel diagnostic systems are also presented.

  6. Advanced camera image data acquisition system for Pi-of-the-Sky

    NASA Astrophysics Data System (ADS)

    Kwiatkowski, Maciej; Kasprowicz, Grzegorz; Pozniak, Krzysztof; Romaniuk, Ryszard; Wrochna, Grzegorz

    2008-11-01

    The paper describes a new generation of high performance, remote control, CCD cameras designed for astronomical applications. A completely new camera PCB was designed, manufactured, tested and commissioned. The CCD chip was positioned in a different way than previously resulting in better performance of the astronomical video data acquisition system. The camera was built using a low-noise, 4Mpixel CCD circuit by STA. The electronic circuit of the camera is highly parameterized and reconfigurable, as well as modular in comparison with the solution of first generation, due to application of open software solutions and FPGA circuit, Altera Cyclone EP1C6. New algorithms were implemented into the FPGA chip. There were used the following advanced electronic circuit in the camera system: microcontroller CY7C68013a (core 8051) by Cypress, image processor AD9826 by Analog Devices, GigEth interface RTL8169s by Realtec, memory SDRAM AT45DB642 by Atmel, CPU typr microprocessor ARM926EJ-S AT91SAM9260 by ARM and Atmel. Software solutions for the camera and its remote control, as well as image data acquisition are based only on the open source platform. There were used the following image interfaces ISI and API V4L2, data bus AMBA, AHB, INDI protocol. The camera will be replicated in 20 pieces and is designed for continuous on-line, wide angle observations of the sky in the research program Pi-of-the-Sky.

  7. Hepatocellular carcinoma: Advances in diagnostic imaging.

    PubMed

    Sun, Haoran; Song, Tianqiang

    2015-10-01

    Thanks to the growing knowledge on biological behaviors of hepatocellular carcinomas (HCC), as well as continuous improvement in imaging techniques and experienced interpretation of imaging features of the nodules in cirrhotic liver, the detection and characterization of HCC has improved in the past decade. A number of practice guidelines for imaging diagnosis have been developed to reduce interpretation variability and standardize management of HCC, and they are constantly updated with advances in imaging techniques and evidence based data from clinical series. In this article, we strive to review the imaging techniques and the characteristic features of hepatocellular carcinoma associated with cirrhotic liver, with emphasis on the diagnostic value of advanced magnetic resonance imaging (MRI) techniques and utilization of hepatocyte-specific MRI contrast agents. We also briefly describe the concept of liver imaging reporting and data systems and discuss the consensus and controversy of major practice guidelines. PMID:26632539

  8. Microscopy imaging device with advanced imaging properties

    SciTech Connect

    Ghosh, Kunal; Burns, Laurie; El Gamal, Abbas; Schnitzer, Mark J.; Cocker, Eric; Ho, Tatt Wei

    2015-11-24

    Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm.sup.2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 .mu.m resolution for an image of the field of view.

  9. [Advances in musculoskeletal MR imaging].

    PubMed

    Ho, Michael; Andreisek, Gustav

    2015-09-01

    Musculoskeletal imaging is a rapidly developing field offering several new techniques. MR neurography provides an additive value with complementary and precise information about peripheral nerves. Hereby, MR neurography not only enables the radiologist to differentiate between a mononeuropathic or a polyneuropathic process, but also helps to find nerve compression syndromes by visualizing the nerve surrounding structures as well. An additional administration of contrast agent enables detection of tumors and inflammation of peripheral nerves. Whole body MRI opens new possibilities for detection and follow-up in oncological disorders, systemic diseases, in pediatric diagnostics and in preventive medicine. Guidelines are useful for an evidence-based application of this technique. MRI is generally considered to be the gold standard in diagnostic imaging of the spine. Continuous technical developments have led to a better image quality. New guidelines for standardized image interpretation and reporting have been published and should be used to avoid loss of information from high resolution imaging to effective treatment. PMID:26331202

  10. Real-time detection of DNA hybridization on microarray using a CCD-based imaging system equipped with a rotated microlens array disk.

    PubMed

    Mogi, Takeyuki; Hatakeyama, Keiichi; Taguchi, Tomoyuki; Wake, Hitoshi; Tanaami, Takeo; Hosokawa, Masahito; Tanaka, Tsuyoshi; Matsunaga, Tadashi

    2011-01-15

    This work describes a novel charge-coupled device (CCD)-based imaging system (MB Biochip Reader™) for real-time detection of DNA hybridization to DNA microarrays. The MB Biochip Reader™ consisted of a laser light source (532 nm), a microlens array for generation of a multi-beam laser, and a CCD for 2-D signal imaging. The MB Biochip Reader™ with a rotated microlens array, allowed large-field imaging (6.2 mm × 7.6 mm with 6.45 μm resolution) with fast time-resolution at 0.2 s without speckle noise. Furthermore, real-time detection of DNA hybridization, which is sufficient to obtain accurate data from tens of thousands of array element per field, was successfully performed without the need for laser scanning. The performance of the MB Biochip Reader™ for DNA microarray imaging was similar to the commercially available photomultiplier tube (PMT)-based microarray scanner, ScanArray Lite. The system potentially could be applied toward real-time analysis in many other fluorescent techniques in addition to real-time DNA microarray analysis. PMID:20951567

  11. Digital monochrome CCD camera for robust pixel correspondant, data compression, and preprocessing in an integrated PC-based image-processing environment

    NASA Astrophysics Data System (ADS)

    Arshad, Norhashim M.; Harvey, David M.; Hobson, Clifford A.

    1996-12-01

    This paper describes the development of a compact digital CCD camera which contains image digitization and processing which interfaces to a personal computer (PC) via a standard enhanced parallel port. Digitizing of precise pixel samples coupled with the provision of putting a single chip FPGA for data processing, became the main digital components of the camera prior to sending the data to the PC. A form of compression scheme is applied so that the digital images may be transferred within the existing parallel port bandwidth. The data is decompressed in the PC environment for a real- time display of the video images using purely native processor resources. Frame capture is built into the camera so that a full uncompressed digital image could be sent for special processing.

  12. Advanced Atmospheric Sounder and Imaging Radiometer (AASIR)

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Design information for the Advanced Atmospheric Sounder and Imaging Radiometer is reported, which was developed to determine the configuration of a sensor for IR and visible imaging. The areas of technology reported include: systems design, optics, mechanics, electronics, detectors, radiative cooler, and radiometric calibration.

  13. Advanced Imaging Algorithms for Radiation Imaging Systems

    SciTech Connect

    Marleau, Peter

    2015-10-01

    The intent of the proposed work, in collaboration with University of Michigan, is to develop the algorithms that will bring the analysis from qualitative images to quantitative attributes of objects containing SNM. The first step to achieving this is to develop an indepth understanding of the intrinsic errors associated with the deconvolution and MLEM algorithms. A significant new effort will be undertaken to relate the image data to a posited three-dimensional model of geometric primitives that can be adjusted to get the best fit. In this way, parameters of the model such as sizes, shapes, and masses can be extracted for both radioactive and non-radioactive materials. This model-based algorithm will need the integrated response of a hypothesized configuration of material to be calculated many times. As such, both the MLEM and the model-based algorithm require significant increases in calculation speed in order to converge to solutions in practical amounts of time.

  14. CCD research. [design, fabrication, and applications

    NASA Technical Reports Server (NTRS)

    Gassaway, J. D.

    1976-01-01

    The fundamental problems encountered in designing, fabricating, and applying CCD's are reviewed. Investigations are described and results and conclusions are given for the following: (1) the development of design analyses employing computer aided techniques and their application to the design of a grapped structure; (2) the role of CCD's in applications to electronic functions, in particular, signal processing; (3) extending the CCD to silicon films on sapphire (SOS); and (4) all aluminum transfer structure with low noise input-output circuits. Related work on CCD imaging devices is summarized.

  15. Advanced MR Imaging of the Visual Pathway.

    PubMed

    Yu, Fang; Duong, Timothy; Tantiwongkosi, Bundhit

    2015-08-01

    Vision is one of our most vital senses, deriving from the eyes as well as structures deep within the intracranial compartment. MR imaging, through its wide selection of sequences, offers an array of structural and functional imaging tools to interrogate this intricate system. This review describes several advanced MR imaging sequences and explores their potential clinical applications as well as areas for further development. PMID:26208415

  16. Imaging of the pancreas: Recent advances

    PubMed Central

    Chaudhary, Vikas; Bano, Shahina

    2011-01-01

    A wide spectrum of anomalies of pancreas and the pancreatic duct system are commonly encountered at radiological evaluation. Diagnosing pancreatic lesions generally requires a multimodality approach. This review highlights the new advances in pancreatic imaging and their applications in the diagnosis and management of pancreatic pathologies. The mainstay techniques include computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound (EUS), radionuclide imaging (RNI) and optical coherence tomography (OCT). PMID:21847450

  17. Characterization of a CCD-based digital x-ray imaging system for small-animal studies: properties of spatial resolution.

    PubMed

    Ouandji, Fabrice; Potter, Eric; Chen, Wei R; Li, Yuhua; Tang, David; Liu, Hong

    2002-05-01

    A digital x-ray imaging system was designed for small-animal studies. This system is a fiber-optics taper-coupled imaging system with two CCD arrays uniquely jointed. The x-ray source of the system has a small focal spot of 20 microm. This digital imaging system contains specially designed shelves to provide magnification levels, ranging from 1.5x to 5x. The system is characterized in terms of its properties of spatial resolution. An observer-based spatial resolution measurement was conducted with a line-pair target and a sector test pattern. The modulation transfer function of the system, with different magnifications, was studied by use of a 10-microm lead slit. The average resolutions at 50% and 5% modulations at 1x magnification were measured as 3.9 and 8.4 lp/mm, respectively, where lp indicates line pairs. With 5x magnification, the 50% and the 5% modulations provided 13.2- and 29.9-lp/mm, respectively, average spatial resolutions. The measurements showed consistency between the two individual CCD arrays; the difference in resolution between the two CCDs is less than 1%, even at high magnifications. PMID:12009151

  18. Advances in optical imaging for pharmacological studies

    PubMed Central

    Arranz, Alicia; Ripoll, Jorge

    2015-01-01

    Imaging approaches are an essential tool for following up over time representative parameters of in vivo models, providing useful information in pharmacological studies. Main advantages of optical imaging approaches compared to other imaging methods are their safety, straight-forward use and cost-effectiveness. A main drawback, however, is having to deal with the presence of high scattering and high absorption in living tissues. Depending on how these issues are addressed, three different modalities can be differentiated: planar imaging (including fluorescence and bioluminescence in vivo imaging), optical tomography, and optoacoustic approaches. In this review we describe the latest advances in optical in vivo imaging with pharmacological applications, with special focus on the development of new optical imaging probes in order to overcome the strong absorption introduced by different tissue components, especially hemoglobin, and the development of multimodal imaging systems in order to overcome the resolution limitations imposed by scattering. PMID:26441646

  19. Advanced noninvasive imaging of spinal vascular malformations

    PubMed Central

    Eddleman, Christopher S.; Jeong, Hyun; Cashen, Ty A.; Walker, Matthew; Bendok, Bernard R.; Batjer, H. Hunt; Carroll, Timothy J.

    2010-01-01

    Spinal vascular malformations (SVMs) are an uncommon, heterogeneous group of vascular anomalies that can render devastating neurological consequences if they are not diagnosed and treated in a timely fashion. Imaging SVMs has always presented a formidable challenge because their clinical and imaging presentations resemble those of neoplasms, demyelination diseases, and infection. Advancements in noninvasive imaging modalities (MR and CT angiography) have increased during the last decade and have improved the ability to accurately diagnose spinal vascular anomalies. In addition, intraoperative imaging techniques have been developed that aid in the intraoperative assessment before, during, and after resection of these lesions with minimal and/or optimal use of spinal digital subtraction angiography. In this report, the authors review recent advancements in the imaging of SVMs that will likely lead to more timely diagnoses and treatment while reducing procedural risk exposure to the patients who harbor these uncommon spinal lesions. PMID:19119895

  20. Recent advances in liver imaging.

    PubMed

    Mutter, D; Soler, L; Marescaux, J

    2010-10-01

    Liver surgery remains a difficult challenge in which preoperative data analysis and strategy definition may play a significant role in the success of the procedure. Medical image processing led to a major improvement of patient care by guiding the surgical gesture. From this initial data, new technologies of virtual reality and augmented reality can increase the potential of such images. The 3D modeling of the liver of patients from their CT scan or MRI thus allows an improved surgical planning. Simulation allows the procedure to be simulated preoperatively and offers the opportunity to train the surgical gesture before carrying it out. These three preoperative steps can be used intraoperatively thanks to the development of augmented reality, which consists of superimposing the preoperative 3D modeling of the patient onto the real intraoperative view of the patient and his/her organs. Augmented reality provides surgeons with a transparent view of the patient. This facilitated the intraoperative identification of the vascular anatomy and the control of the segmental arteries and veins in liver surgery, thus preventing intraoperative bleeding. It can also offer guidance due to the virtual improvement of their real surgical tools, which are tracked in real-time during the procedure. During the surgical procedure, augmented reality, therefore, offers surgeons a transparent view of their patient, which will lead to the automation of the most complex maneuvers. The new ways of processing and analyzing liver images have dramatically changed the approach to liver surgery. PMID:20932146

  1. Chemical Approaches for Advanced Optical Imaging

    NASA Astrophysics Data System (ADS)

    Chen, Zhixing

    Advances in optical microscopy have been constantly expanding our knowledge of biological systems. The achievements therein are a result of close collaborations between physicists/engineers who build the imaging instruments and chemists/biochemists who design the corresponding probe molecules. In this work I present a number of chemical approaches for the development of advanced optical imaging methods. Chapter 1 provides an overview of the recent advances of novel imaging approaches taking advantage of chemical tag technologies. Chapter 2 describes the second-generation covalent trimethoprim-tag as a viable tool for live cell protein-specific labeling and imaging. In Chapter 3 we present a fluorescence lifetime imaging approach to map protein-specific micro-environment in live cells using TMP-Cy3 as a chemical probe. In Chapter 4, we present a method harnessing photo-activatable fluorophores to extend the fundamental depth limit in multi-photon microscopy. Chapter 5 describes the development of isotopically edited alkyne palette for multi-color live cell vibrational imaging of cellular small molecules. These studies exemplify the impact of modern chemical approaches in the development of advanced optical microscopies.

  2. Advanced Microwave/Millimeter-Wave Imaging Technology

    NASA Astrophysics Data System (ADS)

    Shen, Zuowei; Yang, Lu; Luhmann, N. C., Jr.; Domier, C. W.; Ito, N.; Kogi, Y.; Liang, Y.; Mase, A.; Park, H.; Sakata, E.; Tsai, W.; Xia, Z. G.; Zhang, P.

    Millimeter wave technology advances have made possible active and passive millimeter wave imaging for a variety of applications including advanced plasma diagnostics, radio astronomy, atmospheric radiometry, concealed weapon detection, all-weather aircraft landing, contraband goods detection, harbor navigation/surveillance in fog, highway traffic monitoring in fog, helicopter and automotive collision avoidance in fog, and environmental remote sensing data associated with weather, pollution, soil moisture, oil spill detection, and monitoring of forest fires, to name but a few. The primary focus of this paper is on technology advances which have made possible advanced imaging and visualization of magnetohydrodynamic (MHD) fluctuations and microturbulence in fusion plasmas. Topics of particular emphasis include frequency selective surfaces, planar Schottky diode mixer arrays, electronically controlled beam shaping/steering arrays, and high power millimeter wave local oscillator and probe sources.

  3. Advanced MR Imaging of Gliomas: An Update

    PubMed Central

    Chiang, Shih-Wei; Chung, Hsiao-Wen; Tsai, Fong Y.; Chen, Cheng-Yu

    2013-01-01

    Recent advances in the treatment of cerebral gliomas have increased the demands on noninvasive neuroimaging for the diagnosis, therapeutic planning, tumor monitoring, and patient outcome prediction. In the meantime, improved magnetic resonance (MR) imaging techniques have shown much potentials in evaluating the key pathological features of the gliomas, including cellularity, invasiveness, mitotic activity, angiogenesis, and necrosis, hence, further shedding light on glioma grading before treatment. In this paper, an update of advanced MR imaging techniques is reviewed, and their potential roles as biomarkers of tumor grading are discussed. PMID:23862163

  4. Advanced Imaging of Chiari 1 Malformations.

    PubMed

    Fakhri, Akbar; Shah, Manish N; Goyal, Manu S

    2015-10-01

    Type I Chiari malformations are congenital deformities involving cerebellar tonsillar herniation downward through the foramen magnum. Structurally, greater than 5 mm of tonsillar descent in adults and more than 6 mm in children is consistent with type I Chiari malformations. However, the radiographic severity of the tonsillar descent does not always correlate well with the clinical symptomatology. Advanced imaging can help clinically correlate imaging to symptoms. Specifically, cerebrospinal fluid (CSF) flow abnormalities are seen in patients with type I Chiari malformation. Advanced MRI involving cardiac-gated and phase-contrast MRI affords a view of such CSF flow abnormalities. PMID:26408061

  5. A programmable CCD driver circuit for multiphase CCD operation

    NASA Technical Reports Server (NTRS)

    Ewin, Audrey J.; Reed, Kenneth V.

    1989-01-01

    A programmable CCD (charge-coupled device) driver circuit was designed to drive CCDs in multiphased modes. The purpose of the drive electronics is to operate developmental CCD imaging arrays for NASA's tiltable moderate resolution imaging spectrometer (MODIS-T). Five objectives for the driver were considered during its design: (1) the circuit drives CCD electrode voltages between 0 V and +30 V to produce reasonable potential wells, (2) the driving sequence is started with one input signal, (3) the driving sequence is started with one input signal, (4) the circuit allows programming of frame sequences required by arrays of any size, (5) it produces interfacing signals for the CCD and the DTF (detector test facility). Simulation of the driver verified its function with the master clock running up to 10 MHz. This suggests a maximum rate of 400,000 pixels/s. Timing and packaging parameters were verified. The design uses 54 TTL (transistor-transistor logic) chips. Two versions of hardware were fabricated: wirewrap and printed circuit board. Both were verified functionally with a logic analyzer.

  6. Advances of imaging for hepatocellular carcinoma.

    PubMed

    Choi, Byung Ihn

    2010-07-01

    A variety of imaging modalities, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine, and angiography, are currently used in evaluating patients with chronic liver disease and suspected hepatocellular carcinoma (HCC). Further technological advancement will undoubtedly have a major impact on liver tumor imaging. Increased speed of data acquisition and consequently shorter scan times in CT and MRI show further improvement in resolution by further reducing motion artifacts. Development of new contrast materials for liver tumor imaging in US and MRI improve tumor detection and characterization by increasing the contrast resolution. Currently available advanced US techniques in the evaluation of HCC are various harmonic imaging techniques with contrast agents, volume imaging, and recently, US elastography, that has been developing and might play a role in characterizing liver nodules in the future. The latest advance in CT is the multidetector (MD) CT scanner where a 256- or 320-detector CT was introduced. Recent studies describe the high sensitivity of double arterial phase imaging in hepatic tumor detection and the usefulness of CT angiography by using MD CT in a detailed assessment of hepatic arterial anatomy using a three-dimensional dataset. In addition, perfusion CT imaging is also being developed and can be used for the characterization and treatment monitoring of HCC. Dual-energy CT with new technology is also continuously progressing. Advances in MR technology, including hardware and pulse sequence implementation, allow acquisition times to be reduced to the time frame of one breathhold, providing multiphasic dynamic MRI. Functional MRI including diffusion-weighted MRI, MR elastography, and new MR contrast agent with dual function have been investigated for the clinical utility of detection and characterization of HCCs. Functional MRI has a potential to be a promising technique for assessing HCC. PMID:20616584

  7. Dark signal correction for a lukecold frame-transfer CCD. New method and application to the solar imager of the PICARD space mission

    NASA Astrophysics Data System (ADS)

    Hochedez, J.-F.; Timmermans, C.; Hauchecorne, A.; Meftah, M.

    2014-01-01

    Context. Astrophysical observations must be corrected for their imperfections of instrumental origin. When charge-coupled devices (CCDs) are used, their dark signal is one such hindrance. In their pristine state, most CCD pixels are cool, that is, they exhibit a low quasi-uniform dark current, which can be estimated and corrected for. In space, after having been hit by an energetic particle, pixels can turn hot, viz. they start delivering excessive, less predictable, dark current. The hot pixels therefore need to be flagged so that a subsequent analysis may ignore them. Aims: The image data of the PICARD-SODISM solar telescope require dark signal correction and hot pixel identification. Its E2V 42-80 CCD operates at -7.2 °C and has a frame-transfer architecture. Both image and memory zones thus accumulate dark current during integration and readout time, respectively. These two components must be separated in order to estimate the dark signal for any given observation. This is the main purpose of the dark signal model presented in this paper. Methods: The dark signal time-series of every pixel was processed by the unbalanced Haar technique to timestamp when its dark signal changed significantly. In-between these instants, the two components were assumed to be constant, and a robust linear regression, with respect to integration time, provides first estimates and a quality coefficient. The latter serves to assign definitive estimates for this pixel and that period. Results: Our model is part of the SODISM Level 1 data production scheme. To confirm its reliability, we verified on dark frames that it leaves a negligible residual bias (5 e-) and generates a small rms error (25 e- rms). We also examined the distribution of the image zone dark current. The cool pixel level is found to be 4.0 e- pxl-1 s-1, in agreement with the predicted value. The emergence rate of hot pixels was investigated as well. It yields a threshold criterion at 50 e- pxl-1 s-1. The growth rate

  8. Advanced imaging research and development at DARPA

    NASA Astrophysics Data System (ADS)

    Dhar, Nibir K.; Dat, Ravi

    2012-06-01

    Advances in imaging technology have huge impact on our daily lives. Innovations in optics, focal plane arrays (FPA), microelectronics and computation have revolutionized camera design. As a result, new approaches to camera design and low cost manufacturing is now possible. These advances are clearly evident in visible wavelength band due to pixel scaling, improvements in silicon material and CMOS technology. CMOS cameras are available in cell phones and many other consumer products. Advances in infrared imaging technology have been slow due to market volume and many technological barriers in detector materials, optics and fundamental limits imposed by the scaling laws of optics. There is of course much room for improvements in both, visible and infrared imaging technology. This paper highlights various technology development projects at DARPA to advance the imaging technology for both, visible and infrared. Challenges and potentials solutions are highlighted in areas related to wide field-of-view camera design, small pitch pixel, broadband and multiband detectors and focal plane arrays.

  9. Uncooled thermal imaging sensor and application advances

    NASA Astrophysics Data System (ADS)

    Norton, Peter W.; Cox, Stephen; Murphy, Bob; Grealish, Kevin; Joswick, Mike; Denley, Brian; Feda, Frank; Elmali, Loriann; Kohin, Margaret

    2006-05-01

    BAE Systems continues to advance the technology and performance of microbolometer-based thermal imaging modules and systems. 640x480 digital uncooled infrared focal plane arrays are in full production, illustrated by recent production line test data for two thousand focal plane arrays. This paper presents a snapshot of microbolometer technology at BAE Systems and an overview of two of the most important thermal imaging sensor programs currently in production: a family of thermal weapons sights for the United States Army and a thermal imager for the remote weapons station on the Stryker vehicle.

  10. Advanced imaging and visualization in gastrointestinal disorders

    PubMed Central

    Gilja, Odd Helge; Hatlebakk, Jan G; Ødegaard, Svein; Berstad, Arnold; Viola, Ivan; Giertsen, Christopher; Hausken, Trygve; Gregersen, Hans

    2007-01-01

    Advanced medical imaging and visualization has a strong impact on research and clinical decision making in gastroenterology. The aim of this paper is to show how imaging and visualization can disclose structural and functional abnormalities of the gastrointestinal (GI) tract. Imaging methods such as ultrasonography, magnetic resonance imaging (MRI), endoscopy, endosonography, and elastography will be outlined and visualization with Virtual Reality and haptic methods. Ultrasonography is a versatile method that can be used to evaluate antral contractility, gastric emptying, transpyloric flow, gastric configuration, intragastric distribution of meals, gastric accommodation and strain measurement of the gastric wall. Advanced methods for endoscopic ultrasound, three-dimensional (3D) ultrasound, and tissue Doppler (Strain Rate Imaging) provide detailed information of the GI tract. Food hypersensitivity reactions including gastrointestinal reactions due to food allergy can be visualized by ultrasonography and MRI. Development of multi-parametric and multi-modal imaging may increase diagnostic benefits and facilitate fusion of diagnostic and therapeutic imaging in the future. PMID:17457973

  11. Advanced endoscopic imaging to improve adenoma detection

    PubMed Central

    Neumann, Helmut; Nägel, Andreas; Buda, Andrea

    2015-01-01

    Advanced endoscopic imaging is revolutionizing our way on how to diagnose and treat colorectal lesions. Within recent years a variety of modern endoscopic imaging techniques was introduced to improve adenoma detection rates. Those include high-definition imaging, dye-less chromoendoscopy techniques and novel, highly flexible endoscopes, some of them equipped with balloons or multiple lenses in order to improve adenoma detection rates. In this review we will focus on the newest developments in the field of colonoscopic imaging to improve adenoma detection rates. Described techniques include high-definition imaging, optical chromoendoscopy techniques, virtual chromoendoscopy techniques, the Third Eye Retroscope and other retroviewing devices, the G-EYE endoscope and the Full Spectrum Endoscopy-system. PMID:25789092

  12. Advanced technologies for remote sensing imaging applications

    SciTech Connect

    Wood, L.L.

    1993-06-07

    Generating and returning imagery from great distances has been generally associated with national security activities, with emphasis on reliability of system operation. (While the introduction of such capabilities was usually characterized by high levels of innovation, the evolution of such systems has followed the classical track of proliferation of ``standardized items`` expressing ever more incremental technological advances.) Recent focusing of interest on the use of remote imaging systems for commercial and scientific purposes can be expected to induce comparatively rapid advances along the axes of efficiency and technological sophistication, respectively. This paper reviews the most basic reasons for expecting the next decade of advances to dwarf the impressive accomplishments of the past ten years. The impact of these advances clearly will be felt in all major areas of large-scale human endeavor, commercial, military and scientific.

  13. Advanced laser systems for photoacoustic imaging

    NASA Astrophysics Data System (ADS)

    Klosner, Marc; Sampathkumar, Ashwin; Chan, Gary; Wu, Chunbai; Gross, Daniel; Heller, Donald F.

    2015-03-01

    We describe the ongoing development of laser systems for advanced photoacoustic imaging (PAI). We discuss the characteristics of these laser systems and their particular benefits for soft tissue imaging and next-generation breast cancer diagnostics. We provide an overview of laser performance and compare this with other laser systems that have been used for early-stage development of PAI. These advanced systems feature higher pulse energy output at clinically relevant repetition rates, as well as a novel wavelength-cycling output pulse format. Wavelength cycling provides pulse sequences for which the output repeatedly alternates between two wavelengths that provide differential imaging. This capability improves co-registration of captured differential images. We present imaging results of phantoms obtained with a commercial ultrasound detector system and a wavelength-cycling laser source providing ~500 mJ/pulse at 755 and 797 nm, operating at 25 Hz. The results include photoacoustic images and corresponding pulse-echo data from a tissue mimicking phantom containing inclusions, simulating tumors in the breast. We discuss the application of these systems to the contrast-enhanced detection of various tissue types and tumors.

  14. Characteristic analysis on the thermal noise of infrared CCD

    NASA Astrophysics Data System (ADS)

    Zhang, Rong-zhu; Yu, Xing; Liu, Guo-dong

    2014-09-01

    1.064 μm, 1.319 μm and 10.6 μm laser were used to irradiate silicon-based HgCdTe CCD image system. The temperature distribution of detector induced by infrared laser irradiating in the experiment above was simulated. The influence of temperature on photoelectric parameters of HgCdTe CCD was calculated. A CCD physical model of crosstalk saturation was built and the response characteristic of CCD under the influence of thermal noise was analyzed. Result indicated that the rise of temperature induced by laser irradiating little influenced imaging effect of CCD.

  15. Advances in transmission x-ray optics

    SciTech Connect

    Ceglio, N.M.

    1983-01-01

    Recent developments in x-ray optics are reviewed. Specific advances in coded aperture imaging, zone plate lens fabrication, time and space resolved spectroscopy, and CCD x-ray detection are discussed.

  16. Foundations of Advanced Magnetic Resonance Imaging

    PubMed Central

    Bammer, Roland; Skare, Stefan; Newbould, Rexford; Liu, Chunlei; Thijs, Vincent; Ropele, Stefan; Clayton, David B.; Krueger, Gunnar; Moseley, Michael E.; Glover, Gary H.

    2005-01-01

    Summary: During the past decade, major breakthroughs in magnetic resonance imaging (MRI) quality were made by means of quantum leaps in scanner hardware and pulse sequences. Some advanced MRI techniques have truly revolutionized the detection of disease states and MRI can now—within a few minutes—acquire important quantitative information noninvasively from an individual in any plane or volume at comparatively high resolution. This article provides an overview of the most common advanced MRI methods including diffusion MRI, perfusion MRI, functional MRI, and the strengths and weaknesses of MRI at high magnetic field strengths. PMID:15897944

  17. High-power white LED-based system incorporating a CCD Offner imaging spectrometer for real-time fluorescence qPCR measurements

    NASA Astrophysics Data System (ADS)

    Alaruri, Sami D.

    2014-12-01

    An optical system for qPCR fluorescence measurements which incorporates high-power white LEDs, PMMA plastic lenses and an Offner multichannel (imaging) CCD-based spectrometer has been developed and validated. The optical system can detect twenty reaction vessels in an asynchronous manner and up to seven different fluorescent dyes (7 plex) at 1 nM dye concentrations in each of the reaction vessels. Furthermore, PCR curves obtained using the optical measurement system for a genomic deoxyribonucleic acid (DNA) template containing HEX and Texas Red fluorescent probes (fluorophores) are discussed. The spectral resolution, dynamic range and repeatability of the measurement system are < 15 nm, > 3 decades and < 1% CV, respectively.

  18. Occultation Predictions Using CCD Strip-Scanning Astrometry

    NASA Technical Reports Server (NTRS)

    Dunham, Edward W.; Ford, C. H.; Stone, R. P. S.; McDonald, S. W.; Olkin, C. B.; Elliot, J. L.; Witteborn, Fred C. (Technical Monitor)

    1994-01-01

    We are developing the method of CCD strip-scanning astrometry for the purpose of deriving reliable advance predictions for occultations involving small objects in the outer solar system. We are using a camera system based on a Ford/Loral 2Kx2K CCD with the Crossley telescope at Lick Observatory for this work. The columns of die CCD are aligned East-West, the telescope drive is stopped, and the CCD is clocked at the same rate that the stars drift across it. In this way we obtain arbitrary length strip images 20 arcmin wide with 0.58" pixels. Since planets move mainly in RA, it is possible to obtain images of the planet and star to be occulted on the same strip well before the occultation occurs. The strip-to-strip precision (i.e. reproducibility) of positions is limited by atmospheric image motion to about 0.1" rms per strip. However, for objects that are nearby in R.A., the image motion is highly correlated and their relative positions are good to 0.02" rms per strip. We will show that the effects of atmospheric image motion on a given strip can be removed if a sufficient number of strips of a given area have been obtained. Thus, it is possible to reach an rms precision of 0.02" per strip, corresponding to about 0.3 of Pluto or Triton's angular radius. The ultimate accuracy of a prediction based on strip-scanning astrometry is currently limited by the accuracy of the positions of the stars in the astrometric network used and by systematic errors most likely due to the optical system. We will show the results of . the prediction of some recent occultations as examples of the current capabilities and limitations of this technique.

  19. A CCD-based optical CT scanner for high-resolution 3D imaging of radiation dose distributions: equipment specifications, optical simulations and preliminary results

    NASA Astrophysics Data System (ADS)

    Doran, Simon J.; Klein Koerkamp, Koen; Bero, Mamdouh A.; Jenneson, Paul; Morton, Edward J.; Gilboy, Walter B.

    2001-12-01

    Methods based on magnetic resonance imaging for the measurement of three-dimensional distributions of radiation dose are highly developed. However, relatively little work has been done on optical computed tomography (OCT). This paper describes a new OCT scanner based on a broad beam light source and a two-dimensional charge-coupled device (CCD) detector. A number of key design features are discussed including the light source; the scanning tank, turntable and stepper motor control; the diffuser screen onto which images are projected and the detector. It is shown that the non-uniform pixel sensitivity of the low-cost CCD detector used and the granularity of the diffuser screen lead to a serious ring artefact in the reconstructed images. Methods are described for eliminating this. The problems arising from reflection and refraction at the walls of the gel container are explained. Optical ray-tracing simulations are presented for cylindrical containers with a variety of radii and verified experimentally. Small changes in the model parameters lead to large variations in the signal intensity observed in the projection data. The effect of imperfect containers on data quality is discussed and a method based on a 'correction scan' is shown to be successful in correcting many of the related image artefacts. The results of two tomography experiments are presented. In the first experiment, a radiochromic Fricke gel sample was exposed four times in different positions to a 100 kVp x-ray beam perpendicular to the plane of imaging. Images of absorbed dose with slice thickness of 140 μm were acquired, with 'true' in-plane resolution of 560 × 560 μm2 at the edge of the 72 mm field of view and correspondingly higher resolution at the centre. The nominal doses measured correlated well with the known exposure times. The second experiment demonstrated the well known phenomenon of diffusion in the dosemeter gels and yielded a value of (0.12 +/- 0.02) mm2 s-1 for the diffusion

  20. A CCD-based optical CT scanner for high-resolution 3D imaging of radiation dose distributions: equipment specifications, optical simulations and preliminary results.

    PubMed

    Doran, S J; Koerkamp, K K; Bero, M A; Jenneson, P; Morton, E J; Gilboy, W B

    2001-12-01

    Methods based on magnetic resonance imaging for the measurement of three-dimensional distributions of radiation dose are highly developed. However, relatively little work has been done on optical computed tomography (OCT). This paper describes a new OCT scanner based on a broad beam light source and a two-dimensional charge-coupled device (CCD) detector. A number of key design features are discussed including the light source; the scanning tank, turntable and stepper motor control; the diffuser screen onto which images are projected and the detector. It is shown that the non-uniform pixel sensitivity of the low-cost CCD detector used and the granularity of the diffuser screen lead to a serious ring artefact in the reconstructed images. Methods are described for eliminating this. The problems arising from reflection and refraction at the walls of the gel container are explained. Optical ray-tracing simulations are presented for cylindrical containers with a variety of radii and verified experimentally. Small changes in the model parameters lead to large variations in the signal intensity observed in the projection data. The effect of imperfect containers on data quality is discussed and a method based on a 'correction scan' is shown to be successful in correcting many of the related image artefacts. The results of two tomography experiments are presented. In the first experiment, a radiochromic Fricke gel sample was exposed four times in different positions to a 100 kVp x-ray beam perpendicular to the plane of imaging. Images of absorbed dose with slice thickness of 140 microm were acquired. with 'true' in-plane resolution of 560 x 560 microm2 at the edge of the 72 mm field of view and correspondingly higher resolution at the centre. The nominal doses measured correlated well with the known exposure times. The second experiment demonstrated the well known phenomenon of diffusion in the dosemeter gels and yielded a value of (0.12 +/- 0.02) mm2 s(-1) for the diffusion

  1. Use of a speckle reduction technique to improve the reconstruction image quality of CCD-based optical computed tomography scanner

    NASA Astrophysics Data System (ADS)

    Chang, Yuan-Jen

    2015-06-01

    This study proposed a speckle reduction technique (SRT) that employs a rotating diffuser in the parallel beam optical computed tomography (CT). Results showed that the mean and standard deviation of the gray level are 89.79±4.53 and 89.16±2.88 for reconstruction images without SRT and with SRT, respectively. The proposed SRT effectively removed ring artifacts. In addition, two image processing techniques, namely, the mean and Wiener filters, were also used to improve the reconstructed images. The image processing technique alone effectively reduced ring artifacts, but some fluctuations were still observed in the line profiles of the reconstructed images. Results proved that the proposed SRT is a simple method that is easily implemented to improve image quality for parallel beam optical CT. The combination of SRT and image filters was suggested to achieve the best image reconstruction quality through the full removal of ring artifacts.

  2. Terahertz Tools Advance Imaging for Security, Industry

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Picometrix, a wholly owned subsidiary of Advanced Photonix Inc. (API), of Ann Arbor, Michigan, invented the world s first commercial terahertz system. The company improved the portability and capabilities of their systems through Small Business Innovation Research (SBIR) agreements with Langley Research Center to provide terahertz imaging capabilities for inspecting the space shuttle external tanks and orbiters. Now API s systems make use of the unique imaging capacity of terahertz radiation on manufacturing floors, for thickness measurements of coatings, pharmaceutical tablet production, and even art conservation.

  3. CCD Luminescence Camera

    NASA Technical Reports Server (NTRS)

    Janesick, James R.; Elliott, Tom

    1987-01-01

    New diagnostic tool used to understand performance and failures of microelectronic devices. Microscope integrated to low-noise charge-coupled-device (CCD) camera to produce new instrument for analyzing performance and failures of microelectronics devices that emit infrared light during operation. CCD camera also used to indentify very clearly parts that have failed where luminescence typically found.

  4. Wide Dynamic Range CCD Camera

    NASA Astrophysics Data System (ADS)

    Younse, J. M.; Gove, R. J.; Penz, P. A.; Russell, D. E.

    1984-11-01

    A liquid crystal attenuator (LCA) operated as a variable neutral density filter has been attached to a charge-coupled device (CCD) imager to extend the dynamic range of a solid-state TV camera by an order of magnitude. Many applications are best served by a camera with a dynamic range of several thousand. For example, outside security systems must operate unattended with "dawn-to-dusk" lighting conditions. Although this can be achieved with available auto-iris lens assemblies, more elegant solutions which provide the small size, low power, high reliability advantages of solid state technology are now available. This paper will describe one such unique way of achieving these dynamic ranges using standard optics by making the CCD imager's glass cover a controllable neutral density filter. The liquid crystal attenuator's structure and theoretical properties for this application will be described along with measured transmittance. A small integrated TV camera which utilizes a "virtual-phase" CCD sensor coupled to a LCA will be described and test results for a number of the camera's optical and electrical parameters will be given. These include the following camera parameters: dynamic range, Modulation Transfer Function (MTF), spectral response, and uniformity. Also described will be circuitry which senses the ambient scene illuminance and automatically provides feedback signals to appropriately adjust the transmittance of the LCA. Finally, image photographs using this camera, under various scene illuminations, will be shown.

  5. Imaging Tumor Hypoxia to Advance Radiation Oncology

    PubMed Central

    Lee, Chen-Ting; Boss, Mary-Keara

    2014-01-01

    Abstract Significance: Most solid tumors contain regions of low oxygenation or hypoxia. Tumor hypoxia has been associated with a poor clinical outcome and plays a critical role in tumor radioresistance. Recent Advances: Two main types of hypoxia exist in the tumor microenvironment: chronic and cycling hypoxia. Chronic hypoxia results from the limited diffusion distance of oxygen, and cycling hypoxia primarily results from the variation in microvessel red blood cell flux and temporary disturbances in perfusion. Chronic hypoxia may cause either tumor progression or regressive effects depending on the tumor model. However, there is a general trend toward the development of a more aggressive phenotype after cycling hypoxia. With advanced hypoxia imaging techniques, spatiotemporal characteristics of tumor hypoxia and the changes to the tumor microenvironment can be analyzed. Critical Issues: In this review, we focus on the biological and clinical consequences of chronic and cycling hypoxia on radiation treatment. We also discuss the advanced non-invasive imaging techniques that have been developed to detect and monitor tumor hypoxia in preclinical and clinical studies. Future Directions: A better understanding of the mechanisms of tumor hypoxia with non-invasive imaging will provide a basis for improved radiation therapeutic practices. Antioxid. Redox Signal. 21, 313–337. PMID:24329000

  6. Prospects for a Wide Field CCD Camera Aboard NGST

    NASA Astrophysics Data System (ADS)

    Golimowski, D. A.; Ford, H. C.; Tsvetanov, Z. I.; Burrows, C. J.; Krist, J. E.; White, R. L.; Clampin, M.; Rafal, M.; Hartig, G.

    1998-05-01

    The importance of a Next Generation Space Telescope (NGST) for studying the infrared universe has often overshadowed NGST's potential benefit to optical astronomy. As currently envisioned, NGST could also provide views of the visible universe with resolution and sensitivity that are unmatched by any existing ground- or space-based observatory. We discuss the scientific advantages and technical feasibility of placing a wide-field CCD camera aboard NGST. Using simulated data, we compare the imaging performance of such a camera with that achieved or expected with the Keck Telescope and the HST Advanced Camera for Surveys. Finally, we discuss the technical challenges of temperature regulation and radiation shielding for a CCD camera in the NGST environment.

  7. Image stabilization for SWIR advanced optoelectronic device

    NASA Astrophysics Data System (ADS)

    Schiopu, Paul; Manea, Adrian; Cristea, Ionica; Grosu, Neculai; Craciun, Anca-Ileana; Craciun, Alexandru; Granciu, Dana

    2015-02-01

    At long ranges and under low visibility conditions, Advanced Optoelectronic Device provides the signal-to-noise ratio and image quality in the Short-wave Infra-red - SWIR (wavelengths between 1,1 ÷2,5 μm), significantly better than in the near wave infrared - NWIR and visible spectral bands [1,2]. The quality of image is nearly independent of the polarization in the incoming light, but it is influenced by the relative movement between the optical system and the observer (the operators' handshake), and the movement towards the support system (land and air vehicles). All these make it difficult to detect objectives observation in real time. This paper presents some systems enhance which the ability of observation and sighting through the optical systems without the use of the stands, tripods or other means. We have to eliminate the effect of "tremors of the hands" and the vibration in order to allow the use of optical devices by operators on the moving vehicles on land, on aircraft, or on boats, and to provide additional comfort for the user to track the moving object through the optical system, without losing the control in the process of detection and tracking. The practical applications of stabilization image process, in SWIR, are the most advanced part of the optical observation systems available worldwide [3,4,5]. This application has a didactic nature, because it ensures understanding by the students about image stabilization and their participation in research.

  8. The CTIO CCD-TV acquisition camera

    NASA Astrophysics Data System (ADS)

    Walker, Alistair R.; Schmidt, Ricardo

    A prototype CCD-TV camera has been built at CTIO, conceptually similar to the cameras in use at Lick Observatory. A GEC CCD is used as the detector, cooled thermo-electrically to -45C. Pictures are displayed via an IBM PC clone computer and an ITI image display board. Results of tests at the CTIO telescopes are discussed, including comparisons with the RCA ISIT cameras used at present for acquisition and guiding.

  9. Modeling of Proton-Induced CCD Degradation in the Chandra X-Ray Observatory

    NASA Technical Reports Server (NTRS)

    Lo, D. H.; Srour, J. R.

    2003-01-01

    Modeling results are presented for proton-induced degradation of charge-coupled devices (CCDs) used in the Advanced CCD Imaging Spectrometer instrument on the Chandra X-Ray Observatory. A methodology is described that provides insights regarding degradation mechanism and on-orbit performance for front-illuminated and back-illuminated CCDs Proton-induced changes in charge transfer inefficiency are modeled. The observed amount of on-orbit degradation can be accounted for using a proton spectrum at the CCD location that is reduced in magnitude by a factor of approx. 1E5 compared to the spectrum incident on the spacecraft.

  10. Single-spin CCD.

    PubMed

    Baart, T A; Shafiei, M; Fujita, T; Reichl, C; Wegscheider, W; Vandersypen, L M K

    2016-04-01

    Spin-based electronics or spintronics relies on the ability to store, transport and manipulate electron spin polarization with great precision. In its ultimate limit, information is stored in the spin state of a single electron, at which point quantum information processing also becomes a possibility. Here, we demonstrate the manipulation, transport and readout of individual electron spins in a linear array of three semiconductor quantum dots. First, we demonstrate single-shot readout of three spins with fidelities of 97% on average, using an approach analogous to the operation of a charge-coupled device (CCD). Next, we perform site-selective control of the three spins, thereby writing the content of each pixel of this 'single-spin charge-coupled device'. Finally, we show that shuttling an electron back and forth in the array hundreds of times, covering a cumulative distance of 80 μm, has negligible influence on its spin projection. Extrapolating these results to the case of much larger arrays points at a diverse range of potential applications, from quantum information to imaging and sensing. PMID:26727201

  11. Single-spin CCD

    NASA Astrophysics Data System (ADS)

    Baart, T. A.; Shafiei, M.; Fujita, T.; Reichl, C.; Wegscheider, W.; Vandersypen, L. M. K.

    2016-04-01

    Spin-based electronics or spintronics relies on the ability to store, transport and manipulate electron spin polarization with great precision. In its ultimate limit, information is stored in the spin state of a single electron, at which point quantum information processing also becomes a possibility. Here, we demonstrate the manipulation, transport and readout of individual electron spins in a linear array of three semiconductor quantum dots. First, we demonstrate single-shot readout of three spins with fidelities of 97% on average, using an approach analogous to the operation of a charge-coupled device (CCD). Next, we perform site-selective control of the three spins, thereby writing the content of each pixel of this ‘single-spin charge-coupled device’. Finally, we show that shuttling an electron back and forth in the array hundreds of times, covering a cumulative distance of 80 μm, has negligible influence on its spin projection. Extrapolating these results to the case of much larger arrays points at a diverse range of potential applications, from quantum information to imaging and sensing.

  12. A Review of Significant Advances in Neutron Imaging from Conception to the Present

    NASA Astrophysics Data System (ADS)

    Brenizer, J. S.

    This review summarizes the history of neutron imaging with a focus on the significant events and technical advancements in neutron imaging methods, from the first radiograph to more recent imaging methods. A timeline is presented to illustrate the key accomplishments that advanced the neutron imaging technique. Only three years after the discovery of the neutron by English physicist James Chadwick in 1932, neutron imaging began with the work of Hartmut Kallmann and Ernst Kuhn in Berlin, Germany, from 1935-1944. Kallmann and Kuhn were awarded a joint US Patent issued in January 1940. Little progress was made until the mid-1950's when Thewlis utilized a neutron beam from the BEPO reactor at Harwell, marking the beginning of the application of neutron imaging to practical applications. As the film method was improved, imaging moved from a qualitative to a quantitative technique, with applications in industry and in nuclear fuels. Standards were developed to aid in the quantification of the neutron images and the facility's capabilities. The introduction of dynamic neutron imaging (initially called real-time neutron radiography and neutron television) in the late 1970's opened the door to new opportunities and new challenges. As the electronic imaging matured, the introduction of the CCD imaging devices and solid-state light intensifiers helped address some of these challenges. Development of improved imaging devices for the medical community has had a major impact on neutron imaging. Additionally, amorphous silicon sensors provided improvements in temporal resolution, while providing a reasonably large imaging area. The development of new neutron imaging sensors and the development of new neutron imaging techniques in the past decade has advanced the technique's ability to provide insight and understanding of problems that other non-destructive techniques could not provide. This rapid increase in capability and application would not have been possible without the

  13. Advances in Imaging for Atrial Fibrillation Ablation

    PubMed Central

    D'Silva, Andrew; Wright, Matthew

    2011-01-01

    Over the last fifteen years, our understanding of the pathophysiology of atrial fibrillation (AF) has paved the way for ablation to be utilized as an effective treatment option. With the aim of gaining more detailed anatomical representation, advances have been made using various imaging modalities, both before and during the ablation procedure, in planning and execution. Options have flourished from procedural fluoroscopy, electroanatomic mapping systems, preprocedural computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, and combinations of these technologies. Exciting work is underway in an effort to allow the electrophysiologist to assess scar formation in real time. One advantage would be to lessen the learning curve for what are very complex procedures. The hope of these developments is to improve the likelihood of a successful ablation procedure and to allow more patients access to this treatment. PMID:22091384

  14. CCD Camera Observations

    NASA Astrophysics Data System (ADS)

    Buchheim, Bob; Argyle, R. W.

    One night late in 1918, astronomer William Milburn, observing the region of Cassiopeia from Reverend T.H.E.C. Espin's observatory in Tow Law (England), discovered a hitherto unrecorded double star (Wright 1993). He reported it to Rev. Espin, who measured the pair using his 24-in. reflector: the fainter star was 6.0 arcsec from the primary, at position angle 162.4 ^{circ } (i.e. the fainter star was south-by-southeast from the primary) (Espin 1919). Some time later, it was recognized that the astrograph of the Vatican Observatory had taken an image of the same star-field a dozen years earlier, in late 1906. At that earlier epoch, the fainter star had been separated from the brighter one by only 4.8 arcsec, at position angle 186.2 ^{circ } (i.e. almost due south). Were these stars a binary pair, or were they just two unrelated stars sailing past each other? Some additional measurements might have begun to answer this question. If the secondary star was following a curved path, that would be a clue of orbital motion; if it followed a straight-line path, that would be a clue that these are just two stars passing in the night. Unfortunately, nobody took the trouble to re-examine this pair for almost a century, until the 2MASS astrometric/photometric survey recorded it in late 1998. After almost another decade, this amateur astronomer took some CCD images of the field in 2007, and added another data point on the star's trajectory, as shown in Fig. 15.1.

  15. Spatio-temporal prediction of leaf area index of rubber plantation using HJ-1A/1B CCD images and recurrent neural network

    NASA Astrophysics Data System (ADS)

    Chen, Bangqian; Wu, Zhixiang; Wang, Jikun; Dong, Jinwei; Guan, Liming; Chen, Junming; Yang, Kai; Xie, Guishui

    2015-04-01

    Rubber (Hevea brasiliensis) plantations are one of the most important economic forest in tropical area. Retrieving leaf area index (LAI) and its dynamics by remote sensing is of great significance in ecological study and production management, such as yield prediction and post-hurricane damage evaluation. Thirteen HJ-1A/1B CCD images, which possess the spatial advantage of Landsat TM/ETM+ and 2-days temporal resolution of MODIS, were introduced to predict the spatial-temporal LAI of rubber plantation on Hainan Island by Nonlinear AutoRegressive networks with eXogenous inputs (NARX) model. Monthly measured LAIs at 30 stands by LAI-2000 between 2012 and 2013 were used to explore the LAI dynamics and their relationship with spectral bands and seven vegetation indices, and to develop and validate model. The NARX model, which was built base on input variables of day of year (DOY), four spectral bands and weight difference vegetation index (WDVI), possessed good accuracies during the model building for the data set of training (N = 202, R2 = 0.98, RMSE = 0.13), validation (N = 43, R2 = 0.93, RMSE = 0.24) and testing (N = 43, R2 = 0.87, RMSE = 0.31), respectively. The model performed well during field validation (N = 24, R2 = 0.88, RMSE = 0.24) and most of its mapping results showed better agreement (R2 = 0.54-0.58, RMSE = 0.47-0.71) with the field data than the results of corresponding stepwise regression models (R2 = 0.43-0.51, RMSE = 0.52-0.82). Besides, the LAI statistical values from the spatio-temporal LAI maps and their dynamics, which increased dramatically from late March (2.36 ± 0.59) to early May (3.22 ± 0.64) and then gradually slow down until reached the maximum value in early October (4.21 ± 0.87), were quite consistent with the statistical results of the field data. The study demonstrates the feasibility and reliability of retrieving spatio-temporal LAI of rubber plantations by an artificial neural network (ANN) approach, and provides some insight on the

  16. Advanced imaging systems programs at DARPA MTO

    NASA Astrophysics Data System (ADS)

    Dhar, Nibir K.; Elizondo, Lee A.; Dat, Ravi; Elizondo, Shelly L.

    2013-09-01

    In this paper, we review a few selected imaging technology development programs at the Defense Advanced Research Projects Agency (DARPA) in the reflective visible to the emissive/thermal long wave infrared (LWIR) spectral bands. For the reflective visible band, results are shown for two different imagers: a gigapixel monocentric multi-scale camera design that solves the scaling issues for a high pixel count, and a wide field of view and a single photon detection camera with a large dynamic range. Also, a camera with broadband capability covering both reflective and thermal bands (0.5 μm to 5.0 μm) with >80% quantum efficiency is discussed. In the emissive/thermal band, data is presented for both uncooled and cryogenically cooled LWIR detectors with pixel pitches approaching the fundamental detection limits. By developing wafer scale manufacturing processes and reducing the pixel size of uncooled thermal imagers, it is shown that an affordable camera on a chip, capable of seeing through obscurants in day or night, is feasible. Also, the fabrication and initial performance of the world's first 5 μm pixel pitch LWIR camera is discussed. Lastly, we use an initial model to evaluate the signal to noise ratio and noise equivalent differential temperature as a function of well capacity to predict the performance for this thermal imager.

  17. What X-ray images and CCD energy resolution can tell us about the physics of ICM

    NASA Astrophysics Data System (ADS)

    Churazov, E.

    2016-06-01

    X-ray images and moderate-resolution energy spectra provide us with a wealth of data on the global properties of galaxy clusters. Additional information is recored in small scale surface brightness and spectral perturbations. We argue that statistical analysis of many small fluctuations in different X-ray energy bands offers a convenient way of characterizing the nature of perturbations and reveals important clues on the ICM physics and on the AGN feedback process.

  18. Smart image sensors: an emerging key technology for advanced optical measurement and microsystems

    NASA Astrophysics Data System (ADS)

    Seitz, Peter

    1996-08-01

    Optical microsystems typically include photosensitive devices, analog preprocessing circuitry and digital signal processing electronics. The advances in semiconductor technology have made it possible today to integrate all photosensitive and electronical devices on one 'smart image sensor' or photo-ASIC (application-specific integrated circuits containing photosensitive elements). It is even possible to provide each 'smart pixel' with additional photoelectronic functionality, without compromising the fill factor substantially. This technological capability is the basis for advanced cameras and optical microsystems showing novel on-chip functionality: Single-chip cameras with on- chip analog-to-digital converters for less than $10 are advertised; image sensors have been developed including novel functionality such as real-time selectable pixel size and shape, the capability of performing arbitrary convolutions simultaneously with the exposure, as well as variable, programmable offset and sensitivity of the pixels leading to image sensors with a dynamic range exceeding 150 dB. Smart image sensors have been demonstrated offering synchronous detection and demodulation capabilities in each pixel (lock-in CCD), and conventional image sensors are combined with an on-chip digital processor for complete, single-chip image acquisition and processing systems. Technological problems of the monolithic integration of smart image sensors include offset non-uniformities, temperature variations of electronic properties, imperfect matching of circuit parameters, etc. These problems can often be overcome either by designing additional compensation circuitry or by providing digital correction routines. Where necessary for technological or economic reasons, smart image sensors can also be combined with or realized as hybrids, making use of commercially available electronic components. It is concluded that the possibilities offered by custom smart image sensors will influence the design

  19. High performance CCD camera system for digitalisation of 2D DIGE gels.

    PubMed

    Strijkstra, Annemieke; Trautwein, Kathleen; Roesler, Stefan; Feenders, Christoph; Danzer, Daniel; Riemenschneider, Udo; Blasius, Bernd; Rabus, Ralf

    2016-07-01

    An essential step in 2D DIGE-based analysis of differential proteome profiles is the accurate and sensitive digitalisation of 2D DIGE gels. The performance progress of commercially available charge-coupled device (CCD) camera-based systems combined with light emitting diodes (LED) opens up a new possibility for this type of digitalisation. Here, we assessed the performance of a CCD camera system (Intas Advanced 2D Imager) as alternative to a traditionally employed, high-end laser scanner system (Typhoon 9400) for digitalisation of differential protein profiles from three different environmental bacteria. Overall, the performance of the CCD camera system was comparable to the laser scanner, as evident from very similar protein abundance changes (irrespective of spot position and volume), as well as from linear range and limit of detection. PMID:27252121

  20. Electron Trajectory Reconstruction for Advanced Compton Imaging of Gamma Rays

    NASA Astrophysics Data System (ADS)

    Plimley, Brian Christopher

    Gamma-ray imaging is useful for detecting, characterizing, and localizing sources in a variety of fields, including nuclear physics, security, nuclear accident response, nuclear medicine, and astronomy. Compton imaging in particular provides sensitivity to weak sources and good angular resolution in a large field of view. However, the photon origin in a single event sequence is normally only limited to the surface of a cone. If the initial direction of the Compton-scattered electron can be measured, the cone can be reduced to a cone segment with width depending on the uncertainty in the direction measurement, providing a corresponding increase in imaging sensitivity. Measurement of the electron's initial direction in an efficient detection material requires very fine position resolution due to the electron's short range and tortuous path. A thick (650 mum), fully-depleted charge-coupled device (CCD) developed for infrared astronomy has 10.5-mum position resolution in two dimensions, enabling the initial trajectory measurement of electrons of energy as low as 100 keV. This is the first time the initial trajectories of electrons of such low energies have been measured in a solid material. In this work, the CCD's efficacy as a gamma-ray detector is demonstrated experimentally, using a reconstruction algorithm to measure the initial electron direction from the CCD track image. In addition, models of fast electron interaction physics, charge transport and readout were used to generate modeled tracks with known initial direction. These modeled tracks allowed the development and refinement of the reconstruction algorithm. The angular sensitivity of the reconstruction algorithm is evaluated extensively with models for tracks below 480 keV, showing a FWHM as low as 20° in the pixel plane, and 30° RMS sensitivity to the magnitude of the out-of-plane angle. The measurement of the trajectories of electrons with energies as low as 100 keV have the potential to make electron

  1. The Wasilewski sample of emission-line galaxies - Follow-up CCD imaging and spectroscopic and IRAS observations

    NASA Technical Reports Server (NTRS)

    Bothun, Gregory D.; Schmitz, Mark; Halpern, Jules P.; Lonsdale, Carol J.; Impey, Chris

    1989-01-01

    The results of an extensive imaging and spectroscopic follow-up of the objective prism-selected emission line galaxy (ELG) sample of Wasilewski (1982) are presented. Fluxes at 12, 25, 60, and 100 microns were also obtained from the coadded IRAS survey data. ELGs found by objective prism surveys are found to be generally small and underluminous galaxies which usually have higher than average optical surface brightness. The Seyfert detection rate in objective prism surveys is roughly 10 percent and the ratio of the space densities of Seyfert 2 to Seyfert 1 galaxies is significantly larger than unity. Most of the galaxies selected by objective prism surveys are star-forming, late-type spirals which often show disturbed morphology. About 25 percent of the galaxies detected by the surveys are faint, high-excitation metal-poor compact H II regions.

  2. A high-resolution radar and CCD imaging study of crater rays in Mare Serenitatis and Mare Nectaris

    NASA Technical Reports Server (NTRS)

    Campbell, Bruce A.; Bell, James F., III; Zisk, Stanley H.; Hawke, B. R.; Horton, Keith A.

    1992-01-01

    Radar and spectral image processing techniques are reviewed and their application to the rays in Mare Serenitatis and Mare Nectaris is discussed. Analysis of data for Mare Serenitatis shows that the ray that passes west of the Bessel Crater is characterized by up to 40 percent highland ejecta. Radar data show that optically bright ray deposits are characterized by enhanced 1-50 cm scale roughness within the upper meter of the regolith, but not by enhanced 1-10 m blockiness. Stokes vector analysis of the 3.0 cm radar echoes shows that the western portion of the Bessel ejecta blanket is characterized by an anomalously high nondiffuse depolarized return. The ray analyzed in Mare Nectaris passes close to Rosse Crater and is characterized by a cluster of bright secondary craters within a radar-rough halo downrange of Tycho. This downrange deposit is attributed to excavation of local fragmental material by a secondary debris surge.

  3. Recent advances in imaging subcellular processes

    PubMed Central

    Myers, Kenneth A.; Janetopoulos, Christopher

    2016-01-01

    Cell biology came about with the ability to first visualize cells. As microscopy techniques advanced, the early microscopists became the first cell biologists to observe the inner workings and subcellular structures that control life. This ability to see organelles within a cell provided scientists with the first understanding of how cells function. The visualization of the dynamic architecture of subcellular structures now often drives questions as researchers seek to understand the intricacies of the cell. With the advent of fluorescent labeling techniques, better and new optical techniques, and more sensitive and faster cameras, a whole array of questions can now be asked. There has been an explosion of new light microscopic techniques, and the race is on to build better and more powerful imaging systems so that we can further our understanding of the spatial and temporal mechanisms controlling molecular cell biology. PMID:27408708

  4. Recent advances in morphological cell image analysis.

    PubMed

    Chen, Shengyong; Zhao, Mingzhu; Wu, Guang; Yao, Chunyan; Zhang, Jianwei

    2012-01-01

    This paper summarizes the recent advances in image processing methods for morphological cell analysis. The topic of morphological analysis has received much attention with the increasing demands in both bioinformatics and biomedical applications. Among many factors that affect the diagnosis of a disease, morphological cell analysis and statistics have made great contributions to results and effects for a doctor. Morphological cell analysis finds the cellar shape, cellar regularity, classification, statistics, diagnosis, and so forth. In the last 20 years, about 1000 publications have reported the use of morphological cell analysis in biomedical research. Relevant solutions encompass a rather wide application area, such as cell clumps segmentation, morphological characteristics extraction, 3D reconstruction, abnormal cells identification, and statistical analysis. These reports are summarized in this paper to enable easy referral to suitable methods for practical solutions. Representative contributions and future research trends are also addressed. PMID:22272215

  5. Recent advances in imaging subcellular processes.

    PubMed

    Myers, Kenneth A; Janetopoulos, Christopher

    2016-01-01

    Cell biology came about with the ability to first visualize cells. As microscopy techniques advanced, the early microscopists became the first cell biologists to observe the inner workings and subcellular structures that control life. This ability to see organelles within a cell provided scientists with the first understanding of how cells function. The visualization of the dynamic architecture of subcellular structures now often drives questions as researchers seek to understand the intricacies of the cell. With the advent of fluorescent labeling techniques, better and new optical techniques, and more sensitive and faster cameras, a whole array of questions can now be asked. There has been an explosion of new light microscopic techniques, and the race is on to build better and more powerful imaging systems so that we can further our understanding of the spatial and temporal mechanisms controlling molecular cell biology. PMID:27408708

  6. The EMSS catalog of X-ray-selected clusters of galaxies. 1: An atlas of CCD images of 41 distant clusters

    NASA Technical Reports Server (NTRS)

    Gioia, I. M.; Luppino, G. A.

    1994-01-01

    An atlas of deep, wide-field R-band charge coupled device (CCD) images of a complete sample of distant, X-ray-selected clusters of galaxies is presented. These clusters are the 41 most distant (z is greater than or equal to 0.15) and most X-ray-luminous (L(sub x) is greater than or equal to 2 x 10(exp 44) ergs/s) clusters in the Einstein Observatory Extended Medium Sensitivity Survey (EMSS) catalog that are observable from Mauna Kea (delta is greater than -40 deg). The sample spans a redshift range of 0.15 is less than or equal to z is less than or equal to 0.81 and includes at least two and possibly as many as six rich clusters with z is greater than 0.5. For the most part, the data are of superior quality, with a median seeing of 0.8 sec full width half-maximum (FWHM) and coverage of at least 1 Mpc x 1 Mpc in the cluster frame (H(sub 0) = 50; q(sub 0) = 1/2). In addition, we update the available optical, X-ray, and radio data on the entire EMSS sample of 104 clusters. We outline the cluster selection criteria in detail and emphasize that X-ray-selected cluster samples may prove to be more useful for cosmological studies than optically selected samples. The EMSS cluster sample in particular can be exploited for diverse cosmological investigations, as demonstrated by the detection of evolution in the X-ray luminosity function previously reported, and more recently by the discovery of a large number of gravitationally lensed images in these clusters.

  7. Automatic state calibration with CCD cameras

    NASA Astrophysics Data System (ADS)

    Ge, Renyan

    1994-03-01

    The instrumental errors of an analytical plotter derive mainly from the stage of the analytical plotter, so the stage calibration is a very important quality index for evaluating the measurement accuracy of the analytical plotter. With the help of CCD images, realization of high-precision positioning and measurement has become the basic standard for machine vision and real time photogrammetry systems. The software system, which employs some image processing algorithms for the automatic stage calibration with the CCD camera, based on the analytical plotter which SOKKIA researched and developed, is discussed. The reliability and validity are also discussed.

  8. Curved CCD detector devices and arrays for multispectral astrophysical applications and terrestrial stereo panoramic cameras

    NASA Astrophysics Data System (ADS)

    Swain, Pradyumna; Mark, David

    2004-09-01

    The emergence of curved CCD detectors as individual devices or as contoured mosaics assembled to match the curved focal planes of astronomical telescopes and terrestrial stereo panoramic cameras represents a major optical design advancement that greatly enhances the scientific potential of such instruments. In altering the primary detection surface within the telescope"s optical instrumentation system from flat to curved, and conforming the applied CCD"s shape precisely to the contour of the telescope"s curved focal plane, a major increase in the amount of transmittable light at various wavelengths through the system is achieved. This in turn enables multi-spectral ultra-sensitive imaging with much greater spatial resolution necessary for large and very large telescope applications, including those involving infrared image acquisition and spectroscopy, conducted over very wide fields of view. For earth-based and space-borne optical telescopes, the advent of curved CCD"s as the principle detectors provides a simplification of the telescope"s adjoining optics, reducing the number of optical elements and the occurrence of optical aberrations associated with large corrective optics used to conform to flat detectors. New astronomical experiments may be devised in the presence of curved CCD applications, in conjunction with large format cameras and curved mosaics, including three dimensional imaging spectroscopy conducted over multiple wavelengths simultaneously, wide field real-time stereoscopic tracking of remote objects within the solar system at high resolution, and deep field survey mapping of distant objects such as galaxies with much greater multi-band spatial precision over larger sky regions. Terrestrial stereo panoramic cameras equipped with arrays of curved CCD"s joined with associative wide field optics will require less optical glass and no mechanically moving parts to maintain continuous proper stereo convergence over wider perspective viewing fields than

  9. Range-Gated LADAR Coherent Imaging Using Parametric Up-Conversion of IR and NIR Light for Imaging with a Visible-Range Fast-Shuttered Intensified Digital CCD Camera

    SciTech Connect

    YATES,GEORGE J.; MCDONALD,THOMAS E. JR.; BLISS,DAVID E.; CAMERON,STEWART M.; ZUTAVERN,FRED J.

    2000-12-20

    Research is presented on infrared (IR) and near infrared (NIR) sensitive sensor technologies for use in a high speed shuttered/intensified digital video camera system for range-gated imaging at ''eye-safe'' wavelengths in the region of 1.5 microns. The study is based upon nonlinear crystals used for second harmonic generation (SHG) in optical parametric oscillators (OPOS) for conversion of NIR and IR laser light to visible range light for detection with generic S-20 photocathodes. The intensifiers are ''stripline'' geometry 18-mm diameter microchannel plate intensifiers (MCPIIS), designed by Los Alamos National Laboratory and manufactured by Philips Photonics. The MCPIIS are designed for fast optical shattering with exposures in the 100-200 ps range, and are coupled to a fast readout CCD camera. Conversion efficiency and resolution for the wavelength conversion process are reported. Experimental set-ups for the wavelength shifting and the optical configurations for producing and transporting laser reflectance images are discussed.

  10. Recent advances in human viruses imaging studies.

    PubMed

    Florian, Paula Ecaterina; Rouillé, Yves; Ruta, Simona; Nichita, Norica; Roseanu, Anca

    2016-06-01

    Microscopy techniques are often exploited by virologists to investigate molecular details of critical steps in viruses' life cycles such as host cell recognition and entry, genome replication, intracellular trafficking, and release of mature virions. Fluorescence microscopy is the most attractive tool employed to detect intracellular localizations of various stages of the viral infection and monitor the pathogen-host interactions associated with them. Super-resolution microscopy techniques have overcome the technical limitations of conventional microscopy and offered new exciting insights into the formation and trafficking of human viruses. In addition, the development of state-of-the art electron microscopy techniques has become particularly important in studying virus morphogenesis by revealing ground-braking ultrastructural details of this process. This review provides recent advances in human viruses imaging in both, in vitro cell culture systems and in vivo, in the animal models recently developed. The newly available imaging technologies bring a major contribution to our understanding of virus pathogenesis and will become an important tool in early diagnosis of viral infection and the development of novel therapeutics to combat the disease. PMID:27059598

  11. Advances in fluorescence labeling strategies for dynamic cellular imaging

    PubMed Central

    Dean, Kevin M; Palmer, Amy E

    2014-01-01

    Synergistic advances in optical physics, probe design, molecular biology, labeling techniques and computational analysis have propelled fluorescence imaging into new realms of spatiotemporal resolution and sensitivity. This review aims to discuss advances in fluorescent probes and live-cell labeling strategies, two areas that remain pivotal for future advances in imaging technology. Fluorescent protein– and bio-orthogonal–based methods for protein and RNA imaging are discussed as well as emerging bioengineering techniques that enable their expression at specific genomic loci (for example, CRISPR and TALENs). Important attributes that contribute to the success of each technique are emphasized, providing a guideline for future advances in dynamic live-cell imaging. PMID:24937069

  12. Vacuum compatible miniature CCD camera head

    DOEpatents

    Conder, Alan D.

    2000-01-01

    A charge-coupled device (CCD) camera head which can replace film for digital imaging of visible light, ultraviolet radiation, and soft to penetrating x-rays, such as within a target chamber where laser produced plasmas are studied. The camera head is small, capable of operating both in and out of a vacuum environment, and is versatile. The CCD camera head uses PC boards with an internal heat sink connected to the chassis for heat dissipation, which allows for close(0.04" for example) stacking of the PC boards. Integration of this CCD camera head into existing instrumentation provides a substantial enhancement of diagnostic capabilities for studying high energy density plasmas, for a variety of military industrial, and medical imaging applications.

  13. Vacuum compatible miniature CCD camera head

    SciTech Connect

    Conder, A.D.

    2000-06-20

    A charge-coupled device (CCD) camera head is disclosed which can replace film for digital imaging of visible light, ultraviolet radiation, and soft to penetrating x-rays, such as within a target chamber where laser produced plasmas are studied. The camera head is small, capable of operating both in and out of a vacuum environment, and is versatile. The CCD camera head uses PC boards with an internal heat sink connected to the chassis for heat dissipation, which allows for close (0.04 inches for example) stacking of the PC boards. Integration of this CCD camera head into existing instrumentation provides a substantial enhancement of diagnostic capabilities for studying high energy density plasmas, for a variety of military, industrial, and medical imaging applications.

  14. Performance of the Aspect Camera Assembly for the Advanced X-Ray Astrophysics Facility: Imaging

    NASA Technical Reports Server (NTRS)

    Michaels, Dan

    1998-01-01

    The Aspect Camera Assembly (ACA) is a "state-of-the-art" star tracker that provides real-time attitude information to the Advanced X-Ray Astrophysics Facility - Imaging (AXAF-I), and provides imaging data for "post-facto" ground processing. The ACA consists of a telescope with a CCD focal plane, associated focal plane read-out electronics, and an on-board processor that processes the focal plane data to produce star image location reports. On-board star image locations are resolved to 0.8 arcsec, and post-facto algorithms yield 0.2 arcsec star location accuracies (at end of life). The protoflight ACA has been built, along with a high accuracy vacuum test facility. Image position determination has been verified to < 0.2 arcsec accuracies. This paper is a follow-on paper to one presented by the author at the AeroSense '95 conference. This paper presents the "as built" configuration, the tested performance, and the test facility's design and demonstrated accuracy. The ACA has been delivered in anticipation of a August, 1998 shuttle launch.

  15. Typical effects of laser dazzling CCD camera

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen; Zhang, Jianmin; Shao, Bibo; Cheng, Deyan; Ye, Xisheng; Feng, Guobin

    2015-05-01

    In this article, an overview of laser dazzling effect to buried channel CCD camera is given. The CCDs are sorted into staring and scanning types. The former includes the frame transfer and interline transfer types. The latter includes linear and time delay integration types. All CCDs must perform four primary tasks in generating an image, which are called charge generation, charge collection, charge transfer and charge measurement. In camera, the lenses are needed to input the optical signal to the CCD sensors, in which the techniques for erasing stray light are used. And the electron circuits are needed to process the output signal of CCD, in which many electronic techniques are used. The dazzling effects are the conjunct result of light distribution distortion and charge distribution distortion, which respectively derive from the lens and the sensor. Strictly speaking, in lens, the light distribution is not distorted. In general, the lens are so well designed and fabricated that its stray light can be neglected. But the laser is of much enough intensity to make its stray light obvious. In CCD image sensors, laser can induce a so large electrons generation. Charges transfer inefficiency and charges blooming will cause the distortion of the charge distribution. Commonly, the largest signal outputted from CCD sensor is restricted by capability of the collection well of CCD, and can't go beyond the dynamic range for the subsequent electron circuits maintaining normal work. So the signal is not distorted in the post-processing circuits. But some techniques in the circuit can make some dazzling effects present different phenomenon in final image.

  16. A quadrant-CCD star tracker

    NASA Technical Reports Server (NTRS)

    Clampin, M.; Durrance, S. T.; Barkhouser, R.; Golimowski, D. A.; Wald, A.; Fastie, W. G.; Heidtmann, D. L.; Blouke, Morley M.; Westphal, James A.; Janesick, James R.

    1990-01-01

    The characteristics of a quadrant-CCD designed for pointing and tracking are discussed with reference to its use in an adaptive optics program. The quadrant-CCD is used to correct stellar image motion proceeding from atmospheric turbulence by means of a system in which a sensor measures the image offset and sends data to a high-speed tip/tilt mirror. The design and control of the device are detailed, including four 100-micron-square pixels, the quadrant architecture, controller electronics, and data acquisition computer and interface. The transfer function is set forth in the x and y directions, and transfer curves are shown. A laboratory simulation of random image motion was conducted to evaluate the performance of the quadrant-CCD as an image motion sensor, and the experimental results are presented. The suitability of the quadrant-CCD for space-based pointing and tracking uses is demonstrated by this test and two earlier theoretical studies. Some future developments which improve performance capabilities are mentioned.

  17. Electron tubes and image intensifiers; Proceedings of the Meeting, San Jose, CA, Feb. 10, 11, 1992

    NASA Astrophysics Data System (ADS)

    Johnson, C. B.; Laprade, Bruce N.

    Various papers on electron tubes and image intensifiers are presented. Individual topics addressed include: high-performance LLTV CCD camera for nighttime pilotage, characterization and modelling of microchannel-plate intensified-CCD SNR variations with image size, high-resolution vidicon-based readout system for photon-counting streak camera applications, advancement in microchannel-plate technology, and fractal multifiber microchannel plates.

  18. Recent advances in the imaging of hepatocellular carcinoma

    PubMed Central

    You, Myung-Won; Kim, Kyoung Won; Lee, So Jung; Shin, Yong Moon; Kim, Jin Hee; Lee, Moon-Gyu

    2015-01-01

    The role of imaging is crucial for the surveillance, diagnosis, staging and treatment monitoring of hepatocellular carcinoma (HCC). Over the past few years, considerable technical advances were made in imaging of HCCs. New imaging technology, however, has introduced new challenges in our clinical practice. In this article, the current status of clinical imaging techniques for HCC is addressed. The diagnostic performance of imaging techniques in the context of recent clinical guidelines is also presented. PMID:25834808

  19. Hyper Suprime-Cam: CCD readout electronics

    NASA Astrophysics Data System (ADS)

    Nakaya, Hidehiko; Uchida, Tomohisa; Miyatake, Hironao; Aihara, Hiroaki; Doi, Yoshiyuki; Furusawa, Hisanori; Karoji, Hiroshi; Kamata, Yukiko; Kawanomoto, Satoshi; Komiyama, Yutaka; Miyazaki, Satoshi; Morokuma, Tomoki; Tanaka, Manobu; Tanaka, Yoko

    2008-07-01

    Hyper Suprime-Cam is planned to employ about 120 2k×4k fully-depleted CCDs with 4 signal outputs for each. The data size of an image becomes larger than 2Gbytes. All of the CCDs are designed to be readout parallel within 20 seconds, and the readout noise is expected to be 5e. The frontend electronics will be mounted in a vacuumed cryostat, and connected to the backend electronics mounted on the outside of the cryostat. The frontend electronics includes entire analog circuits for CCD including CCD drivers, preamplifiers and ADC. The backend electronics consists of newly developed gigabit Ethernet modules combined with 2Gbytes memory modules, and several supporting boards. We will present the current status of the CCD readout electronics developments for HSC.

  20. Active Pixel Sensors: Are CCD's Dinosaurs?

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.

    1993-01-01

    Charge-coupled devices (CCD's) are presently the technology of choice for most imaging applications. In the 23 years since their invention in 1970, they have evolved to a sophisticated level of performance. However, as with all technologies, we can be certain that they will be supplanted someday. In this paper, the Active Pixel Sensor (APS) technology is explored as a possible successor to the CCD. An active pixel is defined as a detector array technology that has at least one active transistor within the pixel unit cell. The APS eliminates the need for nearly perfect charge transfer -- the Achilles' heel of CCDs. This perfect charge transfer makes CCD's radiation 'soft,' difficult to use under low light conditions, difficult to manufacture in large array sizes, difficult to integrate with on-chip electronics, difficult to use at low temperatures, difficult to use at high frame rates, and difficult to manufacture in non-silicon materials that extend wavelength response.

  1. Advanced x-ray imaging spectrometer

    NASA Technical Reports Server (NTRS)

    Callas, John L. (Inventor); Soli, George A. (Inventor)

    1998-01-01

    An x-ray spectrometer that also provides images of an x-ray source. Coded aperture imaging techniques are used to provide high resolution images. Imaging position-sensitive x-ray sensors with good energy resolution are utilized to provide excellent spectroscopic performance. The system produces high resolution spectral images of the x-ray source which can be viewed in any one of a number of specific energy bands.

  2. SAR coherent change detection (CCD) for search and rescue

    NASA Astrophysics Data System (ADS)

    Mansfield, Arthur W.; Poehler, Paul L.; Rais, Houra

    1997-06-01

    Recent advances in the areas of phase history processing, interferometry, and radargrammetric adjustment have made possible extremely accurate information extraction from synthetic aperture radar (SAR) image pairs by means of interferometric techniques. The potential gain in accuracy is significant since measurements can theoretically be determined to within a fraction of a wavelength (subcentimeter accuracy) as opposed to a fraction of pixel distance (meter accuracy). One promising application of interferometric SAR (IFSAR) is the use of coherent change detection (CCD) over large areas to locate downed aircraft. This application poses an additional challenge since IFSAR must be processed at longer wavelengths to achieve foliage penetration. In this paper a combination of advanced techniques is described for using airborne SAR imagery to carry out this mission. Performance parameters are derived, and some examples are given from actual data.

  3. Universal tool microscope remanufacture based on CCD

    NASA Astrophysics Data System (ADS)

    Kang, Jian; Hu, Zhongxiang; Zhang, Xunming; Zhang, Jiaying

    2006-02-01

    To overcome the drawback of traditional universal tool microscopes, a remanufacturing scheme based on charge coupled devices (CCD) is proposed. In this paper, the remanufacturing of old tool microscopes is replaced gradually by CCD and grating ruler and the development of a novel measuring system designed to directly analyze image of the screw to be measured is discussed. For the analysis of image, such novel image processing methods as adaptive switching median (ASM) filter and edge detection based on the modified Sobel operator are designed. For the line detection algorithm, HOUGH transform also is used to measure the screw parameter. Experiments on screw images demonstrate that the scheme of remanufactured universal tool microscope is of feasibility and the proposed measurement is of validity.

  4. The XMM pn-CCD detector system: First results

    NASA Astrophysics Data System (ADS)

    Braeuninger, H.; Danner, R.; Findeis, N.; Hauff, D.; Holl, P.; Kemmer, J.; Kendziorra, E.; Kraemer, J.; Lechner, P.; Lutz, G.

    1992-12-01

    The pn-CCD (Charge Coupled Device) is a novel type of CCD developed for fast X-ray imaging and spectroscopy for the X-ray Multi Mirror (XMM) satellite mission. Each 200 by 64 pixel large pn-CCD unit with a sensitive area of 3 by 1 sq cm is a fully depleted detector. With the use of the CMOS Amplifier and Multiplexing chip (CAMEX64B) it is possible to read out the 64 CCD channels in parallel before they are multiplexed and sent to an ADC. For the first time the system of a 64 channel pn-CCD together with CAMEX64B readout, ADC conversion, and data acquisition and storage has been brought into operation. First images of an Fe-55 X-ray source are presented and discussed.

  5. Advances in the reconstruction of LBT LINC-NIRVANA images

    NASA Astrophysics Data System (ADS)

    La Camera, A.; Desiderá, G.; Arcidiacono, C.; Boccacci, P.; Bertero, M.

    2007-09-01

    Context: LINC-NIRVANA, the Fizeau interferometer of the Large Binocular Telescope (LBT), will require routine use of image reconstruction methods for data reduction. To this purpose our group has already developed the software package AIRY (Astronomical Image Restoration in interferometrY). Aims: Observations of a target, with different orientations of the baseline of LINC-NIRVANA, will provide images with different orientations with respect to the CCD camera. This rotation effect was not taken into account in our previous work. Therefore in this paper we propose a method able to compensate for the rotation of the field of view. Moreover we investigate acceleration techniques for reducing the computational burden of multiple image deconvolution. Methods: The basic method is a suitable modification of the Richardson-Lucy algorithm, also implementing an approach we proposed for reducing boundary effects. Acceleration techniques, proposed by Biggs & Andrews, are extended and applied to this new algorithm. Finally a method for estimating the unknown point spread function (PSF) by extracting and extrapolating the image of a reference star is developed and implemented. Results: The method introduced for compensating object rotation and reducing boundary effects, as well as its accelerated versions, are tested on simulated LINC-NIRVANA images, using the VLT image of the Crab Nebula as test object. The results are very promising. Moreover the method for PSFs extraction is tested on simulated images, derived from the LBT image of the galaxy NGC 6946 and obtained by convolving this image with PSFs computed by means of the numerical code LOST (Layer Oriented Simulation Tool).

  6. Advance of Molecular Imaging Technology and Targeted Imaging Agent in Imaging and Therapy

    PubMed Central

    Chen, Zhi-Yi; Wang, Yi-Xiang; Lin, Yan; Zhang, Jin-Shan; Yang, Feng; Zhou, Qiu-Lan; Liao, Yang-Ying

    2014-01-01

    Molecular imaging is an emerging field that integrates advanced imaging technology with cellular and molecular biology. It can realize noninvasive and real time visualization, measurement of physiological or pathological process in the living organism at the cellular and molecular level, providing an effective method of information acquiring for diagnosis, therapy, and drug development and evaluating treatment of efficacy. Molecular imaging requires high resolution and high sensitive instruments and specific imaging agents that link the imaging signal with molecular event. Recently, the application of new emerging chemical technology and nanotechnology has stimulated the development of imaging agents. Nanoparticles modified with small molecule, peptide, antibody, and aptamer have been extensively applied for preclinical studies. Therapeutic drug or gene is incorporated into nanoparticles to construct multifunctional imaging agents which allow for theranostic applications. In this review, we will discuss the characteristics of molecular imaging, the novel imaging agent including targeted imaging agent and multifunctional imaging agent, as well as cite some examples of their application in molecular imaging and therapy. PMID:24689058

  7. Advanced imaging in COPD: insights into pulmonary pathophysiology

    PubMed Central

    Milne, Stephen

    2014-01-01

    Chronic obstructive pulmonary disease (COPD) involves a complex interaction of structural and functional abnormalities. The two have long been studied in isolation. However, advanced imaging techniques allow us to simultaneously assess pathological processes and their physiological consequences. This review gives a comprehensive account of the various advanced imaging modalities used to study COPD, including computed tomography (CT), magnetic resonance imaging (MRI), and the nuclear medicine techniques positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Some more recent developments in imaging technology, including micro-CT, synchrotron imaging, optical coherence tomography (OCT) and electrical impedance tomography (EIT), are also described. The authors identify the pathophysiological insights gained from these techniques, and speculate on the future role of advanced imaging in both clinical and research settings. PMID:25478198

  8. Recent Advances in Imaging Alzheimer’s Disease

    PubMed Central

    Braskie, Meredith N.; Toga, Arthur W.; Thompson, Paul M.

    2014-01-01

    Advances in brain imaging technology in the past five years have contributed greatly to the understanding of Alzheimer’s disease (AD). Here, we review recent research related to amyloid imaging, new methods for magnetic resonance imaging analyses, and statistical methods. We also review research that evaluates AD risk factors and brain imaging, in the context of AD prediction and progression. We selected a variety of illustrative studies, describing how they advanced the field and are leading AD research in promising new directions. PMID:22672880

  9. Tuberculosis, advanced - chest x-rays (image)

    MedlinePlus

    ... tissue, and can cause tissue death. These chest x-rays show advanced pulmonary tuberculosis. There are multiple light ... location of cavities within these light areas. The x-ray on the left clearly shows that the opacities ...

  10. Tuberculosis, advanced - chest x-rays (image)

    MedlinePlus

    Tuberculosis is an infectious disease that causes inflammation, the formation of tubercules and other growths within tissue, ... death. These chest x-rays show advanced pulmonary tuberculosis. There are multiple light areas (opacities) of varying ...

  11. Recent advances in ophthalmic molecular imaging.

    PubMed

    Ramos de Carvalho, J Emanuel; Verbraak, Frank D; Aalders, Maurice C; van Noorden, Cornelis J; Schlingemann, Reinier O

    2014-01-01

    The aim of molecular imaging techniques is the visualization of molecular processes and functional changes in living animals and human patients before morphological changes occur at the cellular and tissue level. Ophthalmic molecular imaging is still in its infancy and has mainly been used in small animals for pre-clinical research. The goal of most of these pre-clinical studies is their translation into ophthalmic molecular imaging techniques in clinical care. We discuss various molecular imaging techniques and their applications in ophthalmology. PMID:24529711

  12. Advances in photographic X-ray imaging for solar astronomy

    NASA Technical Reports Server (NTRS)

    Moses, J. Daniel; Schueller, R.; Waljeski, K.; Davis, John M.

    1989-01-01

    The technique of obtaining quantitative data from high resolution soft X-ray photographic images produced by grazing incidence optics was successfully developed to a high degree during the Solar Research Sounding Rocket Program and the S-054 X-Ray Spectrographic Telescope Experiment Program on Skylab. Continued use of soft X-ray photographic imaging in sounding rocket flights of the High Resolution Solar Soft X-Ray Imaging Payload has provided opportunities to further develop these techniques. The developments discussed include: (1) The calibration and use of an inexpensive, commercially available microprocessor controlled drum type film processor for photometric film development; (2) The use of Kodak Technical Pan 2415 film and Kodak SO-253 High Speed Holographic film for improved resolution; and (3) The application of a technique described by Cook, Ewing, and Sutton for determining the film characteristics curves from density histograms of the flight film. Although the superior sensitivity, noise level, and linearity of microchannel plate and CCD detectors attracts the development efforts of many groups working in soft X-ray imaging, the high spatial resolution and dynamic range as well as the reliability and ease of application of photographic media assures the continued use of these techniques in solar X-ray astronomy observations.

  13. Advances in photographic X-ray imaging for solar astronomy

    NASA Technical Reports Server (NTRS)

    Moses, D.; Schueller, R.; Waljeski, K.; Davis, J. M.

    1989-01-01

    The technique of obtaining quantitative data from high resolution soft X-ray photographic images produced by grazing incidence optics was successfully developed to a high degree during the AS&E Solar Research Sounding Rocket Program and the S-054 X-Ray Spectrographic Telescope Experiment Program on Skylab. Continued use of soft X-Ray photographic imaging in sounding rocket flights of the AS&E High Resolution Solar Soft X-Ray Imaging Payload has provided opportunities to further develop these techniques. The developments discussed include: (1) the calibration and use of an inexpensive, commercially available microprocessor controlled drum type film processor for photometric film development, (2) the use of Kodak Technical Pan 2415 film and Kodak SO-253 High Speed Holographic film for improved resolution, and (3) the application of a technique described by Cook, Ewing, and Sutton (1988) for determining the film characteristics curves from density histograms of the flight film. Although the superior sensitivity, noise level, and linearity of microchannel plate and CCD detectors attracts the development efforts of many groups working in soft X-ray imaging, the high spatial resolution and dynamic range as well as the reliability and ease of application of photographic media assures the continued use of these techniques in solar X-ray astronomy observations.

  14. Advanced Imaging Optics Utilizing Wavefront Coding.

    SciTech Connect

    Scrymgeour, David; Boye, Robert; Adelsberger, Kathleen

    2015-06-01

    Image processing offers a potential to simplify an optical system by shifting some of the imaging burden from lenses to the more cost effective electronics. Wavefront coding using a cubic phase plate combined with image processing can extend the system's depth of focus, reducing many of the focus-related aberrations as well as material related chromatic aberrations. However, the optimal design process and physical limitations of wavefront coding systems with respect to first-order optical parameters and noise are not well documented. We examined image quality of simulated and experimental wavefront coded images before and after reconstruction in the presence of noise. Challenges in the implementation of cubic phase in an optical system are discussed. In particular, we found that limitations must be placed on system noise, aperture, field of view and bandwidth to develop a robust wavefront coded system.

  15. Advances in hyperspectral LWIR pushbroom imagers

    NASA Astrophysics Data System (ADS)

    Holma, Hannu; Mattila, Antti-Jussi; Hyvärinen, Timo; Weatherbee, Oliver

    2011-06-01

    Two long-wave infrared (LWIR) hyperspectral imagers have been under extensive development. The first one utilizes a microbolometer focal plane array (FPA) and the second one is based on an Mercury Cadmium Telluride (MCT) FPA. Both imagers employ a pushbroom imaging spectrograph with a transmission grating and on-axis optics. The main target has been to develop high performance instruments with good image quality and compact size for various industrial and remote sensing application requirements. A big challenge in realizing these goals without considerable cooling of the whole instrument is to control the instrument radiation. The challenge is much bigger in a hyperspectral instrument than in a broadband camera, because the optical signal from the target is spread spectrally, but the instrument radiation is not dispersed. Without any suppression, the instrument radiation can overwhelm the radiation from the target even by 1000 times. The means to handle the instrument radiation in the MCT imager include precise instrument temperature stabilization (but not cooling), efficient optical background suppression and the use of background-monitoring-on-chip (BMC) method. This approach has made possible the implementation of a high performance, extremely compact spectral imager in the 7.7 to 12.4 μm spectral range. The imager performance with 84 spectral bands and 384 spatial pixels has been experimentally verified and an excellent NESR of 14 mW/(m2srμm) at 10 μm wavelength with a 300 K target has been achieved. This results in SNR of more than 700. The LWIR imager based on a microbolometer detector array, first time introduced in 2009, has been upgraded. The sensitivity of the imager has improved drastically by a factor of 3 and SNR by about 15 %. It provides a rugged hyperspectral camera for chemical imaging applications in reflection mode in laboratory and industry.

  16. Transmission electron microscope CCD camera

    DOEpatents

    Downing, Kenneth H.

    1999-01-01

    In order to improve the performance of a CCD camera on a high voltage electron microscope, an electron decelerator is inserted between the microscope column and the CCD. This arrangement optimizes the interaction of the electron beam with the scintillator of the CCD camera while retaining optimization of the microscope optics and of the interaction of the beam with the specimen. Changing the electron beam energy between the specimen and camera allows both to be optimized.

  17. Combining advanced imaging processing and low cost remote imaging capabilities

    NASA Astrophysics Data System (ADS)

    Rohrer, Matthew J.; McQuiddy, Brian

    2008-04-01

    Target images are very important for evaluating the situation when Unattended Ground Sensors (UGS) are deployed. These images add a significant amount of information to determine the difference between hostile and non-hostile activities, the number of targets in an area, the difference between animals and people, the movement dynamics of targets, and when specific activities of interest are taking place. The imaging capabilities of UGS systems need to provide only target activity and not images without targets in the field of view. The current UGS remote imaging systems are not optimized for target processing and are not low cost. McQ describes in this paper an architectural and technologic approach for significantly improving the processing of images to provide target information while reducing the cost of the intelligent remote imaging capability.

  18. Advances in cardiac magnetic resonance imaging of congenital heart disease.

    PubMed

    Driessen, Mieke M P; Breur, Johannes M P J; Budde, Ricardo P J; van Oorschot, Joep W M; van Kimmenade, Roland R J; Sieswerda, Gertjan Tj; Meijboom, Folkert J; Leiner, Tim

    2015-01-01

    Due to advances in cardiac surgery, survival of patients with congenital heart disease has increased considerably during the past decades. Many of these patients require repeated cardiovascular magnetic resonance imaging to assess cardiac anatomy and function. In the past decade, technological advances have enabled faster and more robust cardiovascular magnetic resonance with improved image quality and spatial as well as temporal resolution. This review aims to provide an overview of advances in cardiovascular magnetic resonance hardware and acquisition techniques relevant to both pediatric and adult patients with congenital heart disease and discusses the techniques used to assess function, anatomy, flow and tissue characterization. PMID:25552386

  19. Advances in Small Animal Imaging Systems

    NASA Astrophysics Data System (ADS)

    Loudos, George K.

    2007-11-01

    The rapid growth in genetics and molecular biology combined with the development of techniques for genetically engineering small animals has led to an increased interest in in vivo laboratory animal imaging during the past few years. For this purpose, new instrumentation, data acquisition strategies, and image processing and reconstruction techniques are being developed, researched and evaluated. The aim of this article is to give a short overview of the state of the art technologies for high resolution and high sensitivity molecular imaging techniques, primarily positron emission tomography (PET) and single photon emission computed tomography (SPECT). The basic needs of small animal imaging will be described. The evolution in instrumentation in the past two decades, as well as the commercially available systems will be overviewed. Finally, the new trends in detector technology and preliminary results from challenging applications will be presented. For more details a number of references are provided.

  20. Advances in Small Animal Imaging Systems

    SciTech Connect

    Loudos, George K.

    2007-11-26

    The rapid growth in genetics and molecular biology combined with the development of techniques for genetically engineering small animals has led to an increased interest in in vivo laboratory animal imaging during the past few years. For this purpose, new instrumentation, data acquisition strategies, and image processing and reconstruction techniques are being developed, researched and evaluated. The aim of this article is to give a short overview of the state of the art technologies for high resolution and high sensitivity molecular imaging techniques, primarily positron emission tomography (PET) and single photon emission computed tomography (SPECT). The basic needs of small animal imaging will be described. The evolution in instrumentation in the past two decades, as well as the commercially available systems will be overviewed. Finally, the new trends in detector technology and preliminary results from challenging applications will be presented. For more details a number of references are provided.

  1. Advanced Image Search: A Strategy for Creating Presentation Boards

    ERIC Educational Resources Information Center

    Frey, Diane K.; Hines, Jean D.; Swinker, Mary E.

    2008-01-01

    Finding relevant digital images to create presentation boards requires advanced search skills. This article describes a course assignment involving a technique designed to develop students' literacy skills with respect to locating images of desired quality and content from Internet databases. The assignment was applied in a collegiate apparel…

  2. Study on CCD measurement of temperature field in laser molten pool

    NASA Astrophysics Data System (ADS)

    Lei, Jian-bo; Yang, Xi-chen; Wang, Yun-shan; Li, Hui-shan

    2005-01-01

    The quality of laser remanufacturing depends on temperature field distribution in laser molten pool. In this paper, two-dimensional temperature field model and CCD measurement of temperature field were developed. According to radiant transfer function, bright of light signal of temperature field grabbed by CCD was transformed to spectral radiant signal. A new system model for CCD measurement of temperature filed was proposed. It concluded optical system, CCD camera, image plate, orientating laser, special image software and computer. Thermal image signal received by CCD is transformed to digital signal by image plate. After processing digital image signal by computer, Temperature field distribution can be obtained by thermal image displaying. It was proved that CCD Measurement of molten pool temperature field was available. Automatic control of laser remanufacturing processing could be achieved by feedback control of thermal radiant signal.

  3. Center for Advanced Signal and Imaging Sciences Workshop 2004

    SciTech Connect

    McClellan, J H; Carrano, C; Poyneer, L; Palmer, D; Baker, K; Chen, D; London, R; Weinert, G; Brase, J; Paglieroni, D; Lopez, A; Grant, C W; Wright, W; Burke, M; Miller, W O; DeTeresa, S; White, D; Toeppen, J; Haugen, P; Kamath, C; Nguyen, T; Manay, S; Newsam, S; Cantu-Paz, E; Pao, H; Chang, J; Chambers, D; Leach, R; Paulson, C; Romero, C E; Spiridon, A; Vigars, M; Welsh, P; Zumstein, J; Romero, K; Oppenheim, A; Harris, D B; Dowla, F; Brown, C G; Clark, G A; Ong, M M; Clance, T J; Kegelmeyer, l M; Benzuijen, M; Bliss, E; Burkhart, S; Conder, A; Daveler, S; Ferguson, W; Glenn, S; Liebman, J; Norton, M; Prasad, R; Salmon, T; Kegelmeyer, L M; Hafiz, O; Cheung, S; Fodor, I; Aufderheide, M B; Bary, A; Martz, Jr., H E; Burke, M W; Benson, S; Fisher, K A; Quarry, M J

    2004-11-15

    Welcome to the Eleventh Annual C.A.S.I.S. Workshop, a yearly event at the Lawrence Livermore National Laboratory, presented by the Center for Advanced Signal & Image Sciences, or CASIS, and sponsored by the LLNL Engineering Directorate. Every November for the last 10 years we have convened a diverse set of engineering and scientific talent to share their work in signal processing, imaging, communications, controls, along with associated fields of mathematics, statistics, and computing sciences. This year is no exception, with sessions in Adaptive Optics, Applied Imaging, Scientific Data Mining, Electromagnetic Image and Signal Processing, Applied Signal Processing, National Ignition Facility (NIF) Imaging, and Nondestructive Characterization.

  4. STIS-01 CCD Functional

    NASA Astrophysics Data System (ADS)

    Valenti, Jeff

    2001-07-01

    This activity measures the baseline performance and commandability of the CCD subsystem. Only primary amplifier D is used. Bias, Dark, and Flat Field exposures are taken in order to measure read noise, dark current, CTE, and gain. Numerous bias frames are taken to permit construction of "superbias" frames in which the effects of read noise have been rendered negligible. Dark exposures are made outside the SAA. Full frame and binned observations are made, with binning factors of 1x1 and 2x2. Finally, tungsten lamp exposures are taken through narrow slits to confirm the slit positions in the current database. All exposures are internals. This is a reincarnation of SM3A proposal 8502 with some unnecessary tests removed from the program.

  5. Advanced prism-grating-prism imaging spectrograph in online industrial applications

    NASA Astrophysics Data System (ADS)

    Vaarala, Tapio; Aikio, Mauri; Keraenen, Heimo

    1997-08-01

    Imaging spectrographs have traditionally been utilized in aerial and remote sensing applications. A novel, compact and inexpensive imaging spectrograph developed by VTT Electronics is now available. It contains a multichannel fiber optic sensor head, a dispersive prism-grating-prism (PGP) component and digital CCD matrix camera capable of area integration. In rolled steel manufacturing, a protective oil film is applied on steel to resist corrosion while in transport and storage. The main problems in the oiling machine are film thickness control and jet failures. In this application, the spectrum of fluorescence of an oil film was measured simultaneously with parallel fibers. A relatively simple calibration and analysis procedure was used to calculate the oil film thickness. On-line color control for color reproduction is essential in both consumer and industrial products. The instrument was tested and analyzed for measuring differences in color by multivariate analysis of the spectra and by color space coordinate estimation. In general, a continuous spectrum is not absolute requirement. In these two examples, filter-based measurement would probably cost less thana PGP spectrograph solution. On the other hand, by measuring the spectrum and using an advanced signal processing algorithm one production version will cover all installations in both applications. In practice, only the fiber sensor mechanics need to be modified.

  6. Design of a multifunction astronomical CCD camera

    NASA Astrophysics Data System (ADS)

    Yao, Dalei; Wen, Desheng; Xue, Jianru; Chen, Zhi; Wen, Yan; Jiang, Baotan; Xi, Jiangbo

    2015-07-01

    To satisfy the requirement of the astronomical observation, a novel timing sequence of frame transfer CCD is proposed. The multiple functions such as the adjustments of work pattern, exposure time and frame frequency are achieved. There are four work patterns: normal, standby, zero exposure and test. The adjustment of exposure time can set multiple exposure time according to the astronomical observation. The fame frequency can be adjusted when dark target is imaged and the maximum exposure time cannot satisfy the requirement. On the design of the video processing, offset correction and adjustment of multiple gains are proposed. Offset correction is used for eliminating the fixed pattern noise of CCD. Three gains pattern can improve the signal to noise ratio of astronomical observation. Finally, the images in different situations are collected and the system readout noise is calculated. The calculation results show that the designs in this paper are practicable.

  7. Advances in Optical Spectroscopy and Imaging of Breast Lesions

    SciTech Connect

    Demos, S; Vogel, A J; Gandjbakhche, A H

    2006-01-03

    A review is presented of recent advances in optical imaging and spectroscopy and the use of light for addressing breast cancer issues. Spectroscopic techniques offer the means to characterize tissue components and obtain functional information in real time. Three-dimensional optical imaging of the breast using various illumination and signal collection schemes in combination with image reconstruction algorithms may provide a new tool for cancer detection and monitoring of treatment.

  8. Advances in noninvasive imaging of melanoma.

    PubMed

    Menge, Tyler D; Pellacani, Giovanni

    2016-03-01

    Melanoma is the most dangerous type of skin cancer and its incidence has risen sharply in recent decades. Early detection of disease is critical for improving patient outcomes. Any pigmented lesion that is clinically concerning must be removed by biopsy for morphologic investigation on histology. However, biopsies are invasive and can cause significant morbidity, and their accuracy in detecting melanoma may be limited by sampling error. The advent of noninvasive imaging devices has allowed for assessment of intact skin, thereby minimizing the need for biopsy; and these technologies are increasingly being used in the diagnosis and management of melanoma. Reflectance confocal microscopy, optical coherence tomography, ultrasonography, and multispectral imaging are noninvasive imaging techniques that have emerged as diagnostic aids to physical exam and/or conventional dermoscopy. This review summarizes the current knowledge about these techniques and discusses their practical applications and limitations. PMID:26963113

  9. Functional knee assessment with advanced imaging.

    PubMed

    Amano, Keiko; Li, Qi; Ma, C Benjamin

    2016-06-01

    The purpose of anterior cruciate ligament (ACL) reconstruction is to restore the native stability of the knee joint and to prevent further injury to meniscus and cartilage, yet studies have suggested that joint laxity remains prevalent in varying degrees after ACL reconstruction. Imaging can provide measurements of translational and rotational motions of the tibiofemoral joint that may be too small to detect in routine physical examinations. Various imaging modalities, including fluoroscopy, computed tomography (CT), and magnetic resonance imaging (MRI), have emerged as powerful methods in measuring the minute details involved in joint biomechanics. While each technique has its own strengths and limitations, they have all enhanced our understanding of the knee joint under various stresses and movements. Acquiring the knowledge of the complex and dynamic motions of the knee after surgery would help lead to improved surgical techniques and better patient outcomes. PMID:27052009

  10. SHG nanoprobes: advancing harmonic imaging in biology.

    PubMed

    Dempsey, William P; Fraser, Scott E; Pantazis, Periklis

    2012-05-01

    Second harmonic generating (SHG) nanoprobes have recently emerged as versatile and durable labels suitable for in vivo imaging, circumventing many of the inherent drawbacks encountered with classical fluorescent probes. Since their nanocrystalline structure lacks a central point of symmetry, they are capable of generating second harmonic signal under intense illumination - converting two photons into one photon of half the incident wavelength - and can be detected by conventional two-photon microscopy. Because the optical signal of SHG nanoprobes is based on scattering, rather than absorption as in the case of fluorescent probes, they neither bleach nor blink, and the signal does not saturate with increasing illumination intensity. When SHG nanoprobes are used to image live tissue, the SHG signal can be detected with little background signal, and they are physiologically inert, showing excellent long-term photostability. Because of their photophysical properties, SHG nanoprobes provide unique advantages for molecular imaging of living cells and tissues with unmatched sensitivity and temporal resolution. PMID:22392481

  11. Advanced MEMS-based infrared imager

    NASA Astrophysics Data System (ADS)

    Chen, Ming

    2003-04-01

    Infrared radiation imager is of important for a wide range of applications. IR infrared imagers have not been widely available due to cost and complexity issues. A major cost of IR imager is associated with the requirements of cooling and pixel-level integration with electronic amplifier and read-out circuitry that are often incompatible with the detector materials. Recent research activities have lead to a new class of IR imager based on thermally isolated MEMS (micro-electromechanical systems) arrays whose bending can be directly detected by optical means. This approach eliminates the need for cooling and complex electronic multiplexers, holding the potential to drastically reduce IR imager cost. However, MEMS based IR imaging devices demonstrated to date are less sensitive than the commercially available ones. We have established a comprehensive finite element model (FEM) using Ansys tool. An accurate computer model for the proposed MEME IR detector is critical for the device development and fabrication. The model greatly enhanced our capability to cost effectively optimize the design from concept to fabrication layout. Our model predicts the deformation of this pixel structure under a surface stress for both thermal and photo-induced effects under various conditions. This simulation model provided a design base for new generation of optical MEMS IR sensors that has higher sensitivity and the potential of incorporating passive thermal amplification. Our simple MEMS design incorporates optical read-out, which eliminates the drawback of electronic means that inevitably introduce additional signal loss due to thermal contact made to the detector element. When packaged under vacuum environment, significant sensitivity improvement is anticipated. The deflection of a cantilever as a function of a rise in its temperature is determined by the classical thermomechanical governing equation for a bimaterial cantilever beam. Our finite element model is established using

  12. Advanced Optical Imaging Techniques for Neurodevelopment

    PubMed Central

    Wu, Yicong; Christensen, Ryan; Colón-Ramos, Daniel; Shroff, Hari

    2013-01-01

    Over the past decade, developmental neuroscience has been transformed by the widespread application of confocal and two-photon fluorescence microscopy. Even greater progress is imminent, as recent innovations in microscopy now enable imaging with increased depth, speed, and spatial resolution; reduced phototoxicity; and in some cases without external fluorescent probes. We discuss these new techniques and emphasize their dramatic impact on neurobiology, including the ability to image neurons at depths exceeding 1 mm, to observe neurodevelopment noninvasively throughout embryogenesis, and to visualize neuronal processes or structures that were previously too small or too difficult to target with conventional microscopy. PMID:23831260

  13. Solid state imagers and their applications; Proceedings of the Meeting, Cannes, France, November 26, 27, 1985

    NASA Technical Reports Server (NTRS)

    Declerck, Gilbert J. (Editor)

    1986-01-01

    Topics treated include the use of semiconductor imagers in high energy particle physics, an X-ray image sensor based on an optical TDI-CCD imager, and an electron-sensitive CCD readout array for a circular-scan streak tube. Papers are presented on the pan-imager, high resolution linear arrays, the reduction of reflection losses in solid-state image sensors, a high resolution CCD imager module with swing operation, large area CCD image sensors for scientific applications, and new readout techniques for frame transfer CCDs. Consideration is given to advanced optoelectronical sensors for autonomous rendezvous/docking and proximity operations in space, the testing and characterization of CCDs for the Rosat star sensors, an advanced radial camera for the Hubble Space Telescope, and scanning or staring infrared imagers.

  14. Advances in Lymphatic Imaging and Drug Delivery

    SciTech Connect

    Nune, Satish K.; Gunda, Padmaja; Majeti, Bharat K.; Thallapally, Praveen K.; Laird, Forrest M.

    2011-09-10

    Cancer remains the second leading cause of death after heart disease in the US. While metastasized cancers such as breast, prostate, and colon are incurable, before their distant spread, these diseases will have invaded the lymphatic system as a first step in their progression. Hence, proper evaluation of the disease state of the lymphatics which drain a tumor site is crucial to staging and the formation of a treatment plan. Current lymphatic imaging modalities with visible dyes and radionucleotide tracers offer limited sensitivity and poor resolution; however, newer tools using nanocarriers, quantum dots, and magnetic resonance imaging promise to vastly improve the staging of lymphatic spread without needless biopsies. Concurrent with the improvement of lymphatic imaging agents, has been the development of drug carriers that can localize chemotherapy to the lymphatic system, thus improving the treatment of localized disease while minimizing the exposure of healthy organs to cytotoxic drugs. This review will focus on polymeric systems that have been developed for imaging and drug delivery to the lymph system, how these new devices improve upon current technologies, and where further improvement is needed.

  15. Advances in image registration and fusion

    NASA Astrophysics Data System (ADS)

    Steer, Christopher; Rogers, Jeremy; Smith, Moira; Heather, Jamie; Bernhardt, Mark; Hickman, Duncan

    2008-03-01

    Many image fusion systems involving passive sensors require the accurate registration of the sensor data prior to performing fusion. Since depth information is not readily available in such systems, all registration algorithms are intrinsically approximations based upon various assumption about the depth field. Although often overlooked, many registration algorithms can break down in certain situations and this may adversely affect the image fusion performance. In this paper, we discuss a framework for quantifying the accuracy and robustness of image registration algorithms which allows a more precise understanding of their shortcomings. In addition, some novel algorithms have been investigated that overcome some of these limitations. A second aspect of this work has considered the treatment of images from multiple sensors whose angular and spatial separation is large and where conventional registration algorithms break down (typically greater than a few degrees of separation). A range of novel approaches is reported which exploit the use of parallax to estimate depth information and reconstruct a geometrical model of the scene. The imagery can then be combined with this geometrical model to render a variety of useful representations of the data. These techniques (which we term Volume Registration) show great promise as a means of gathering and presenting 3D and 4D scene information for both military and civilian applications.

  16. Multispectral laser imaging for advanced food analysis

    NASA Astrophysics Data System (ADS)

    Senni, L.; Burrascano, P.; Ricci, M.

    2016-07-01

    A hardware-software apparatus for food inspection capable of realizing multispectral NIR laser imaging at four different wavelengths is herein discussed. The system was designed to operate in a through-transmission configuration to detect the presence of unwanted foreign bodies inside samples, whether packed or unpacked. A modified Lock-In technique was employed to counterbalance the significant signal intensity attenuation due to transmission across the sample and to extract the multispectral information more efficiently. The NIR laser wavelengths used to acquire the multispectral images can be varied to deal with different materials and to focus on specific aspects. In the present work the wavelengths were selected after a preliminary analysis to enhance the image contrast between foreign bodies and food in the sample, thus identifying the location and nature of the defects. Experimental results obtained from several specimens, with and without packaging, are presented and the multispectral image processing as well as the achievable spatial resolution of the system are discussed.

  17. Linejitter and geometric calibration of CCD-cameras

    NASA Astrophysics Data System (ADS)

    Beyer, Horst A.

    Precise radiometric and geometric transmission of images from CCD-sensor to memory is a fundamental aspect of CCD-camera calibration. Linejitter and other degradation occurring during transmission are major limiting factors of the precision attainable with most current CCD-cameras and framegrabbers. The video signal, synchronisation signals and principal electronic components involved in synchronisation and transmission are analysed and their influence on linejitter discussed. A method for signal transmission with the elimination of linejitter and other degradations is shown. Methods for the determination and correction of linejitter are discussed.

  18. CCD/CID Processors Would Offer Greater Precision

    NASA Technical Reports Server (NTRS)

    Barhen, Jacob; Toomarian, Nikzad; Fijany, Amir

    1995-01-01

    Charge-coupled-device/charge-injection-device (CCD/CID) data processors of proposed type offer advantages of massively parallel computational architecture and high computational speed typical of older CCD/CID data processors, but with increased precision. Useful in performing matrix vector multiplications in variety of applications, including solving partial differential equations, processing signal and image data, control computations, and neural-network simulations. Greater precision of proposed devices help to ensure accuracy in CCD/CID implementations of pseudospectral neural networks - particular class of artificial neural networks especially suited to solving nonlinear differential equations.

  19. Recent advances in radiology and medical imaging

    SciTech Connect

    Steiner, R.E.; Sherwood, T.

    1986-01-01

    The first chapter, on the radiology of arthritis, is an overview. The second and seventh chapters are on the chest the former, on adult respiratory distress syndrome, is a brief summary, and the latter, on digital radiography of the chest with the prototype slit-scanning technique. The third chapter reviews computed tomography of the lumbar spine. The following two chapters are on MR imaging, one on the central nervous system (covering demyelinating diseases, cardiovascular disease, infections, and tumors), with excellent illustrations; and one on MR imaging of the body. The illustrations are good. The following chapter is on extracardiac digital subtraction angiography (DSA), with an interesting table comparing and contrasting conventional angiography with both intraveneous and intraarterial DSA. The eighth chapter on pediatric imaging fits a world of experience. Chapter 9 is an update on contrast media, while the next chapter is on barium infusion examination of the small intestine. The final three chapters are concerned with the present state of angioplasty, interventional radiology in the urinary tract.

  20. Advanced image analysis for the preservation of cultural heritage

    NASA Astrophysics Data System (ADS)

    France, Fenella G.; Christens-Barry, William; Toth, Michael B.; Boydston, Kenneth

    2010-02-01

    The Library of Congress' Preservation Research and Testing Division has established an advanced preservation studies scientific program for research and analysis of the diverse range of cultural heritage objects in its collection. Using this system, the Library is currently developing specialized integrated research methodologies for extending preservation analytical capacities through non-destructive hyperspectral imaging of cultural objects. The research program has revealed key information to support preservation specialists, scholars and other institutions. The approach requires close and ongoing collaboration between a range of scientific and cultural heritage personnel - imaging and preservation scientists, art historians, curators, conservators and technology analysts. A research project of the Pierre L'Enfant Plan of Washington DC, 1791 had been undertaken to implement and advance the image analysis capabilities of the imaging system. Innovative imaging options and analysis techniques allow greater processing and analysis capacities to establish the imaging technique as the first initial non-invasive analysis and documentation step in all cultural heritage analyses. Mapping spectral responses, organic and inorganic data, topography semi-microscopic imaging, and creating full spectrum images have greatly extended this capacity from a simple image capture technique. Linking hyperspectral data with other non-destructive analyses has further enhanced the research potential of this image analysis technique.

  1. Advanced Imaging Among Health Maintenance Organization Enrollees With Cancer

    PubMed Central

    Loggers, Elizabeth T.; Fishman, Paul A.; Peterson, Do; O'Keeffe-Rosetti, Maureen; Greenberg, Caprice; Hornbrook, Mark C.; Kushi, Lawrence H.; Lowry, Sarah; Ramaprasan, Arvind; Wagner, Edward H.; Weeks, Jane C.; Ritzwoller, Debra P.

    2014-01-01

    Purpose: Fee-for-service (FFS) Medicare expenditures for advanced imaging studies (defined as computed tomography [CT], magnetic resonance imaging [MRI], positron emission tomography [PET] scans, and nuclear medicine studies [NM]) rapidly increased in the past two decades for patients with cancer. Imaging rates are unknown for patients with cancer, whether under or over age 65 years, in health maintenance organizations (HMOs), where incentives may differ. Materials and Methods: Incident cases of breast, colorectal, lung, prostate, leukemia, and non-Hodgkin lymphoma (NHL) cancers diagnosed in 2003 and 2006 from four HMOs in the Cancer Research Network were used to determine 2-year overall mean imaging counts and average total imaging costs per HMO enrollee by cancer type for those under and over age 65. Results: There were 44,446 incident cancer patient cases, with a median age of 75 (interquartile range, 71-81), and 454,029 imaging procedures were performed. The mean number of images per patient increased from 7.4 in 2003 to 12.9 in 2006. Rates of imaging were similar across age groups, with the exception of greater use of echocardiograms and NM studies in younger patients with breast cancer and greater use of PET among younger patients with lung cancer. Advanced imaging accounted for approximately 41% of all imaging, or approximately 85% of the $8.7 million in imaging expenditures. Costs were nearly $2,000 per HMO enrollee; costs for younger patients with NHL, leukemia, and lung cancer were nearly $1,000 more in 2003. Conclusion: Rates of advanced imaging appear comparable among FFS and HMO participants of any age with these six cancers. PMID:24844241

  2. Comparison of a CCD and an APS for soft X-ray diffraction

    NASA Astrophysics Data System (ADS)

    Stewart, Graeme; Bates, R.; Blue, A.; Clark, A.; Dhesi, S. S.; Maneuski, D.; Marchal, J.; Steadman, P.; Tartoni, N.; Turchetta, R.

    2011-12-01

    We compare a new CMOS Active Pixel Sensor (APS) to a Princeton Instruments PIXIS-XO: 2048B Charge Coupled Device (CCD) with soft X-rays tested in a synchrotron beam line at the Diamond Light Source (DLS). Despite CCDs being established in the field of scientific imaging, APS are an innovative technology that offers advantages over CCDs. These include faster readout, higher operational temperature, in-pixel electronics for advanced image processing and reduced manufacturing cost. The APS employed was the Vanilla sensor designed by the MI3 collaboration and funded by an RCUK Basic technology grant. This sensor has 520 x 520 square pixels, of size 25 μm on each side. The sensor can operate at a full frame readout of up to 20 Hz. The sensor had been back-thinned, to the epitaxial layer. This was the first time that a back-thinned APS had been demonstrated at a beam line at DLS. In the synchrotron experiment soft X-rays with an energy of approximately 708 eV were used to produce a diffraction pattern from a permalloy sample. The pattern was imaged at a range of integration times with both sensors. The CCD had to be operated at a temperature of -55°C whereas the Vanilla was operated over a temperature range from 20°C to -10°C. We show that the APS detector can operate with frame rates up to two hundred times faster than the CCD, without excessive degradation of image quality. The signal to noise of the APS is shown to be the same as that of the CCD at identical integration times and the response is shown to be linear, with no charge blooming effects. The experiment has allowed a direct comparison of back thinned APS and CCDs in a real soft x-ray synchrotron experiment.

  3. Recent advances in echocardiography: strain and strain rate imaging

    PubMed Central

    Mirea, Oana; Duchenne, Jurgen; Voigt, Jens-Uwe

    2016-01-01

    Deformation imaging by echocardiography is a well-established research tool which has been gaining interest from clinical cardiologists since the introduction of speckle tracking. Post-processing of echo images to analyze deformation has become readily available at the fingertips of the user. New parameters such as global longitudinal strain have been shown to provide added diagnostic value, and ongoing efforts of the imaging societies and industry aimed at harmonizing methods will improve the technique further. This review focuses on recent advances in the field of echocardiographic strain and strain rate imaging, and provides an overview on its current and potential future clinical applications. PMID:27158476

  4. Advanced High-Speed Framing Camera Development for Fast, Visible Imaging Experiments

    SciTech Connect

    Amy Lewis, Stuart Baker, Brian Cox, Abel Diaz, David Glass, Matthew Martin

    2011-05-11

    The advances in high-voltage switching developed in this project allow a camera user to rapidly vary the number of output frames from 1 to 25. A high-voltage, variable-amplitude pulse train shifts the deflection location to the new frame location during the interlude between frames, making multiple frame counts and locations possible. The final deflection circuit deflects to five different frame positions per axis, including the center position, making for a total of 25 frames. To create the preset voltages, electronically adjustable {+-}500 V power supplies were chosen. Digital-to-analog converters provide digital control of the supplies. The power supplies are clamped to {+-}400 V so as not to exceed the voltage ratings of the transistors. A field-programmable gated array (FPGA) receives the trigger signal and calculates the combination of plate voltages for each frame. The interframe time and number of frames are specified by the user, but are limited by the camera electronics. The variable-frame circuit shifts the plate voltages of the first frame to those of the second frame during the user-specified interframe time. Designed around an electrostatic image tube, a framing camera images the light present during each frame (at the photocathode) onto the tube’s phosphor. The phosphor persistence allows the camera to display multiple frames on the phosphor at one time. During this persistence, a CCD camera is triggered and the analog image is collected digitally. The tube functions by converting photons to electrons at the negatively charged photocathode. The electrons move quickly toward the more positive charge of the phosphor. Two sets of deflection plates skew the electron’s path in horizontal and vertical (x axis and y axis, respectively) directions. Hence, each frame’s electrons bombard the phosphor surface at a controlled location defined by the voltages on the deflection plates. To prevent the phosphor from being exposed between frames, the image tube

  5. Dyslexia: advances in clinical and imaging studies.

    PubMed

    Koeda, Tatsuya; Seki, Ayumi; Uchiyama, Hitoshi; Sadato, Norihiro

    2011-03-01

    The aim of this report is to describe the characteristics of Japanese dyslexia, and to demonstrate several of our studies about the extraction of these characteristic and their neurophysiological and neuroimaging abnormalities, as well as advanced studies of phonological awareness and the underlying neural substrate. Based on these results, we have proposed a 2-step approach for remedial education (e-learning web site: http://www.dyslexia-koeda.jp/). The first step is decoding, which decreases reading errors, and the second is vocabulary learning, which improves reading fluency. This 2-step approach is designed to serve first grade children. In addition, we propose the RTI (response to intervention) model as a desirable system for remedial education. PMID:21146943

  6. Advanced and Conventional Magnetic Resonance Imaging in Neuropsychiatric Lupus.

    PubMed

    Sarbu, Nicolae; Bargalló, Núria; Cervera, Ricard

    2015-01-01

    Neuropsychiatric lupus is a major diagnostic challenge, and a main cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). Magnetic resonance imaging (MRI) is, by far, the main tool for assessing the brain in this disease. Conventional and advanced MRI techniques are used to help establishing the diagnosis, to rule out alternative diagnoses, and recently, to monitor the evolution of the disease. This review explores the neuroimaging findings in SLE, including the recent advances in new MRI methods. PMID:26236469

  7. Advanced and Conventional Magnetic Resonance Imaging in Neuropsychiatric Lupus

    PubMed Central

    Sarbu, Nicolae; Bargalló, Núria; Cervera, Ricard

    2015-01-01

    Neuropsychiatric lupus is a major diagnostic challenge, and a main cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). Magnetic resonance imaging (MRI) is, by far, the main tool for assessing the brain in this disease. Conventional and advanced MRI techniques are used to help establishing the diagnosis, to rule out alternative diagnoses, and recently, to monitor the evolution of the disease. This review explores the neuroimaging findings in SLE, including the recent advances in new MRI methods. PMID:26236469

  8. Medical x-ray-sensitive array based on CCD

    NASA Astrophysics Data System (ADS)

    Gnedenko, Valeri G.; Krasnjuk, Andrey A.; Larionov, Sergei V.; Phainberg, Evgeni M.; Shilin, Victor A.; Skrylev, Alexander S.; Stenin, Vladimir J.

    1996-04-01

    The achievements of CCD technology allow to design X-ray sensitive solid-state images for various medicine applications. The first medical systems have been created for using in dental practice and diagnosis. This radiovisiographic method allows to reduce X-ray exposure by 80%, except any films and provide paralleled diagnosis capacities which revolutionize every day practice. In the future a mosaic scanner with CCD chips will be used for detecting breast cancer.

  9. Advances in CT imaging for urolithiasis

    PubMed Central

    Andrabi, Yasir; Patino, Manuel; Das, Chandan J.; Eisner, Brian; Sahani, Dushyant V.; Kambadakone, Avinash

    2015-01-01

    Urolithiasis is a common disease with increasing prevalence worldwide and a lifetime-estimated recurrence risk of over 50%. Imaging plays a critical role in the initial diagnosis, follow-up and urological management of urinary tract stone disease. Unenhanced helical computed tomography (CT) is highly sensitive (>95%) and specific (>96%) in the diagnosis of urolithiasis and is the imaging investigation of choice for the initial assessment of patients with suspected urolithiasis. The emergence of multi-detector CT (MDCT) and technological innovations in CT such as dual-energy CT (DECT) has widened the scope of MDCT in the stone disease management from initial diagnosis to encompass treatment planning and monitoring of treatment success. DECT has been shown to enhance pre-treatment characterization of stone composition in comparison with conventional MDCT and is being increasingly used. Although CT-related radiation dose exposure remains a valid concern, the use of low-dose MDCT protocols and integration of newer iterative reconstruction algorithms into routine CT practice has resulted in a substantial decrease in ionizing radiation exposure. In this review article, our intent is to discuss the role of MDCT in the diagnosis and post-treatment evaluation of urolithiasis and review the impact of emerging CT technologies such as dual energy in clinical practice. PMID:26166961

  10. Satisfaction of search experiments in advanced imaging

    NASA Astrophysics Data System (ADS)

    Berbaum, Kevin S.

    2012-03-01

    The objective of our research is to understand the perception of multiple abnormalities in an imaging examination and to develop strategies for improved diagnostic. We are one of the few laboratories in the world pursuing the goal of reducing detection errors through a better understanding of the underlying perceptual processes involved. Failure to detect an abnormality is the most common class of error in diagnostic imaging and generally is considered the most serious by the medical community. Many of these errors have been attributed to "satisfaction of search," which occurs when a lesion is not reported because discovery of another abnormality has "satisfied" the goal of the search. We have gained some understanding of the mechanisms of satisfaction of search (SOS) traditional radiographic modalities. Currently, there are few interventions to remedy SOS error. For example, patient history that the prompts specific abnormalities, protects the radiologist from missing them even when other abnormalities are present. The knowledge gained from this programmatic research will lead to reduction of observer error.

  11. Advances in CT imaging for urolithiasis.

    PubMed

    Andrabi, Yasir; Patino, Manuel; Das, Chandan J; Eisner, Brian; Sahani, Dushyant V; Kambadakone, Avinash

    2015-01-01

    Urolithiasis is a common disease with increasing prevalence worldwide and a lifetime-estimated recurrence risk of over 50%. Imaging plays a critical role in the initial diagnosis, follow-up and urological management of urinary tract stone disease. Unenhanced helical computed tomography (CT) is highly sensitive (>95%) and specific (>96%) in the diagnosis of urolithiasis and is the imaging investigation of choice for the initial assessment of patients with suspected urolithiasis. The emergence of multi-detector CT (MDCT) and technological innovations in CT such as dual-energy CT (DECT) has widened the scope of MDCT in the stone disease management from initial diagnosis to encompass treatment planning and monitoring of treatment success. DECT has been shown to enhance pre-treatment characterization of stone composition in comparison with conventional MDCT and is being increasingly used. Although CT-related radiation dose exposure remains a valid concern, the use of low-dose MDCT protocols and integration of newer iterative reconstruction algorithms into routine CT practice has resulted in a substantial decrease in ionizing radiation exposure. In this review article, our intent is to discuss the role of MDCT in the diagnosis and post-treatment evaluation of urolithiasis and review the impact of emerging CT technologies such as dual energy in clinical practice. PMID:26166961

  12. CCD correlated quadruple sampling processor

    NASA Technical Reports Server (NTRS)

    Gaalema, S. D. (Inventor)

    1981-01-01

    A correlated quadruple sampling processor for improved signal-to-noise ratio in the output of a charge-coupled device (CCD) is comprised of: switching means for momentarily clamping a CCD signal line at a first reference level A before a CCD data pulse and then obtaining a first data sample B with respect to the reference A during a CCD data pulse, and storing the positive sample B-A; switching means for momentarily clamping the CCD signal line a second time at the level C during the presence of the CCD data pulse and then obtaining a second data sample D with respect to the reference level C after the CCD data pulse, and storing the negative sample D-C; and means for obtaining the difference between the stored samples +(B-A) and -(D-C), thus increasing the net signal amplitude by a factor of about 2 while the noise would be increased by only a factor of square root of 2 since there will be no correlation in the noise between the double samples +(B-A) and -(D-C) effectively added.

  13. ADVANCES IN MOLECULAR IMAGING OF PANCREATIC BETA CELLS

    PubMed Central

    Lin, Mai; Lubag, Angelo; McGuire, Michael J.; Seliounine, Serguei Y.; Tsyganov, Edward N.; Antich, Peter P.; Sherry, A. Dean; Brown, Kathlynn C.; Sun, Xiankai

    2009-01-01

    The development of non-invasive imaging methods for early diagnosis of the beta cell associated metabolic diseases, including type 1 and type 2 diabetes (T1D and T2D), has recently drawn considerable interest from the molecular imaging community as well as clinical investigators. Due to the challenges imposed by the location of the pancreas, the sparsely dispersed beta cell population within the pancreas, and the poor understanding of the pathogenesis of the diseases, clinical diagnosis of beta cell abnormalities is still limited. Current diagnostic methods are invasive, often inaccurate, and usually performed post-onset of the disease. Advances in imaging techniques for probing beta cell mass and function are needed to address this critical health care problem. A variety of currently available imaging techniques have been tested for the assessment of the pancreatic beta cell islets. Here we discuss the current advances in magnetic resonance imaging (MRI), bioluminescence imaging (BLI), and nuclear imaging for the study of beta cell diseases. Spurred by early successes in nuclear imaging techniques for beta cells, especially positron emission tomography (PET), the need for beta cell specific ligands has expanded. Progress in the field for obtaining such ligands is presented. Additionally, we report our preliminary efforts of developing such a peptidic ligand for PET imaging of the pancreatic beta cells. PMID:18508529

  14. Advanced terahertz imaging system performance model for concealed weapon identification

    NASA Astrophysics Data System (ADS)

    Murrill, Steven R.; Redman, Brian; Espinola, Richard L.; Franck, Charmaine C.; Petkie, Douglas T.; De Lucia, Frank C.; Jacobs, Eddie L.; Griffin, Steven T.; Halford, Carl E.; Reynolds, Joe

    2007-04-01

    The U.S. Army Night Vision and Electronic Sensors Directorate (NVESD) and the U.S. Army Research Laboratory (ARL) have developed a terahertz-band imaging system performance model for detection and identification of concealed weaponry. The details of this MATLAB-based model which accounts for the effects of all critical sensor and display components, and for the effects of atmospheric attenuation, concealment material attenuation, and active illumination, were reported on at the 2005 SPIE Europe Security and Defence Symposium. The focus of this paper is to report on recent advances to the base model which have been designed to more realistically account for the dramatic impact that target and background orientation can have on target observability as related to specular and Lambertian reflections captured by an active-illumination-based imaging system. The advanced terahertz-band imaging system performance model now also accounts for target and background thermal emission, and has been recast into a user-friendly, Windows-executable tool. This advanced THz model has been developed in support of the Defense Advanced Research Project Agency's (DARPA) Terahertz Imaging Focal-Plane Technology (TIFT) program. This paper will describe the advanced THz model and its new radiometric sub-model in detail, and provide modeling and experimental results on target observability as a function of target and background orientation.

  15. Earth Observing-1 Advanced Land Imager: Radiometric Response Calibration

    NASA Technical Reports Server (NTRS)

    Mendenhall, J. A.; Lencioni, D. E.; Evans, J. B.

    2000-01-01

    The Advanced Land Imager (ALI) is one of three instruments to be flown on the first Earth Observing mission (EO-1) under NASA's New Millennium Program (NMP). ALI contains a number of innovative features, including a wide field of view optical design, compact multispectral focal plane arrays, non-cryogenic HgCdTe detectors for the short wave infrared bands, and silicon carbide optics. This document outlines the techniques adopted during ground calibration of the radiometric response of the Advanced Land Imager. Results from system level measurements of the instrument response, signal-to-noise ratio, saturation radiance, and dynamic range for all detectors of every spectral band are also presented.

  16. [Interventional MR imaging: state of the art and technological advances].

    PubMed

    Viard, R; Rousseau, J

    2008-01-01

    Due to its excellent soft tissue contrast and lack of ionizing radiation, MR imaging is well suited for interventional procedures. MRI is being increasingly used for guidance during percutaneous procedures or surgery. Technical advances in interventional MR imaging are reviewed in this paper. Ergonomical factors with improved access to patients as well as advances in informatics, electronics and robotics largely explain this increasing role. Different elements are discussed from improved access to patients in the scanners to improved acquisition pulse sequences. Selected clinical applications and recent publications will be presented to illustrate the current status of this technique. PMID:18288022

  17. Advanced Imaging Catheter: Final Project Report

    SciTech Connect

    Krulevitch, P; Colston, B; DaSilva, L; Hilken, D; Kluiwstra, J U; Lee, A P; London, R; Miles, R; Schumann, D; Seward, K; Wang, A

    2001-07-20

    Minimally invasive surgery (MIS) is an approach whereby procedures conventionally performed with large and potentially traumatic incisions are replaced by several tiny incisions through which specialized instruments are inserted. Early MIS, often called laparoscopic surgery, used video cameras and laparoscopes to visualize and control the medical devices, which were typically cutting or stapling tools. More recently, catheter-based procedures have become a fast growing sector of all surgeries. In these procedures, small incisions are made into one of the main arteries (e.g. femoral artery in the thigh), and a long thin hollow tube is inserted and positioned near the target area. The key advantage of this technique is that recovery time can be reduced from months to a matter of days. In the United States, over 700,000 catheter procedures are performed annually representing a market of over $350 million. Further growth in this area will require significant improvements in the current catheter technology. In order to effectively navigate a catheter through the tortuous vessels of the body, two capabilities must exist: imaging and positioning. In most cases, catheter procedures rely on radiography for visualization and manual manipulation for positioning of the device. Radiography provides two-dimensional, global images of the vasculature and cannot be used continuously due to radiation exposure to both the patient and physician. Intravascular ultrasound devices are available for continuous local imaging at the catheter tip, but these devices cannot be used simultaneously with therapeutic devices. Catheters are highly compliant devices, and manipulating the catheter is similar to pushing on a string. Often, a guide wire is used to help position the catheter, but this procedure has its own set of problems. Three characteristics are used to describe catheter maneuverability: (1) pushability -- the amount of linear displacement of the distal end (inside body) relative to

  18. STIS CCD Saturation Limits Cycle 21

    NASA Astrophysics Data System (ADS)

    Proffitt, Charles

    2013-10-01

    The goal of this program is to measure the level at which individual STIS CCD pixels stop responding linearly to added photons as a function of position on the detector. Tests will be done at both GAIN=1 and GAIN=4 at a variety of positions on the detector. At each position and gain we will take 6 to 8 HITM1 CCD MIRVIS lamp exposures at exposures levels ranging from ~ 0.4X to 2X full well, using the 0.09X29 aperture. Non-standard MSM positions will be used to image this slit at five different rows along the detector. At each of these rows, two different mirror tilts will be used to allow this narrow aperture to cover the full width of the detector.

  19. Imaging spectrometer technologies for advanced Earth remote sensing

    NASA Technical Reports Server (NTRS)

    Wellman, J. B.; Breckinridge, J. B.; Kuperfman, P.; Salazar, R. P.; Sigurdson, K. B.

    1982-01-01

    A major requirement of multispectral imaging systems for advanced Earth remote sensing is the provision for greater spectral resolution and more versatile spectral band selection. The imaging spectrometer instrument concept provides this versatility by the combination of pushbroom imaging and spectrally dispersing optics using area array detectors in the focal plane. The shuttle imaging spectrometer concept achieves 10- and 20-meter ground instantaneous fields of view with 20-nanometer spectral resolution from Earth Orbit. Onboard processing allows the selection of spectral bands during flight; this, in turn, permits the sensor parameters to be tailored to the experiment objectives. Advances in optical design, infrared detector arrays, and focal plane cooling indicate the feasibility of the instrument concept and support the practicability of a validation flight experiment for the shuttle in the late 1980s.

  20. Recent Advances in Molecular, Multimodal and Theranostic Ultrasound Imaging

    PubMed Central

    Kiessling, Fabian; Fokong, Stanley; Bzyl, Jessica; Lederle, Wiltrud; Palmowski, Moritz; Lammers, Twan

    2014-01-01

    Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of many different diseases. In this context, US contrast agents can improve lesion delineation, characterization and therapy response evaluation. US contrast agents are usually micrometer-sized gas bubbles, stabilized with soft or hard shells. By conjugating antibodies to the microbubble (MB) surface, and by incorporating diagnostic agents, drugs or nucleic acids into or onto the MB shell, molecular, multimodal and theranostic MB can be generated. We here summarize recent advances in molecular, multimodal and theranostic US imaging, and introduce concepts how such advanced MB can be generated, applied and imaged. Examples are given for their use to image and treat oncological, cardiovascular and neurological diseases. Furthermore, we discuss for which therapeutic entities incorporation into (or conjugation to) MB is meaningful, and how US-mediated MB destruction can increase their extravasation, penetration, internalization and efficacy. PMID:24316070

  1. Imaging spectrometer technologies for advanced earth remote sensing

    NASA Technical Reports Server (NTRS)

    Wellman, J. B.; Breckinridge, J. B.; Kupferman, P.; Salazar, R. P.; Sigurdson, K. B.

    1982-01-01

    A major requirement of multispectral imaging systems for advanced earth remote sensing is the provision for greater spectral resolution and more versatile spectral band selection. The imaging spectrometer instrument concept provides this versatility by the combination of pushbroom imaging and spectrally dispersing optics using area array detectors in the focal plane. The shuttle imaging spectrometer concept achieves 10- and 20-meter ground instantaneous fields of view with 20-nanometer spectral resolution from earth orbit. Onboard processing allows the selection of spectral bands during flight; this, in turn, permits the sensor parameters to be tailored to the experiment objectives. Advances in optical design, infrared detector arrays, and focal plane cooling indicate the feasibility of the instrument concept and support the practicability of a validation flight experiment for the shuttle in the late 1980s. Previously announced in STAR as N83-28542

  2. Advanced digital detectors for neutron imaging.

    SciTech Connect

    Doty, F. Patrick

    2003-12-01

    Neutron interrogation provides unique information valuable for Nonproliferation & Materials Control and other important applications including medicine, airport security, protein crystallography, and corrosion detection. Neutrons probe deep inside massive objects to detect small defects and chemical composition, even through high atomic number materials such as lead. However, current detectors are bulky gas-filled tubes or scintillator/PM tubes, which severely limit many applications. Therefore this project was undertaken to develop new semiconductor radiation detection materials to develop the first direct digital imaging detectors for neutrons. The approach relied on new discovery and characterization of new solid-state sensor materials which convert neutrons directly to electronic signals via reactions BlO(n,a)Li7 and Li6(n,a)T.

  3. A 128K-bit CCD buffer memory system

    NASA Technical Reports Server (NTRS)

    Siemens, K. H.; Wallace, R. W.; Robinson, C. R.

    1976-01-01

    A prototype system was implemented to demonstrate that CCD's can be applied advantageously to the problem of low power digital storage and particularly to the problem of interfacing widely varying data rates. 8K-bit CCD shift register memories were used to construct a feasibility model 128K-bit buffer memory system. Peak power dissipation during a data transfer is less than 7 W., while idle power is approximately 5.4 W. The system features automatic data input synchronization with the recirculating CCD memory block start address. Descriptions are provided of both the buffer memory system and a custom tester that was used to exercise the memory. The testing procedures and testing results are discussed. Suggestions are provided for further development with regards to the utilization of advanced versions of CCD memory devices to both simplified and expanded memory system applications.

  4. A microprocessor-controlled CCD star tracker

    NASA Technical Reports Server (NTRS)

    Salomon, P. M.; Goss, W. C.

    1976-01-01

    The STELLAR (Star Tracker for Economical Long Life Attitude Reference) utilizes an image sensing Charge-Coupled Device (CCD) operating under microprocessor control. This approach results in a new type of high-accuracy star tracker which can be adapted to a wide variety of different space flight applications through software changes only. The STELLAR determines two-axis star positions by computing the element and the interelement interpolated centroid positions of the star images. As many as 10 stars may be tracked simultaneously, providing significantly increased stability and accuracy. A detailed description of the STELLAR is presented along with measurements of system performance obtained from an operating breadboard model.

  5. SCREEN photometric property detection system based on area CCD

    NASA Astrophysics Data System (ADS)

    Yan, Fu-cai; Ye, Wei; Xu, Yu; Wang, Chao; Zhang, Yu-wei

    2011-08-01

    The photometric property detection of screen display is crucial for screen display quality test. Traditional photometry detection technologies were based on photoelectric sensors such as silicon photocell, photo-electric multiplier and CdS, which can detect only some isolated points. To break the limitation of randomness, incompleteness and detection accuracy in current technologies, we designed a screen photometric detection system based on area CCD. The system consists of photometric image sensor, photometric image acquisition hardware and photometric image analyzing software. The photometric image sensor, which adopts optical lens, optical filters and area CCD, adapts its spectrum response property to fit the spectrum luminous efficiency curve V (λ) by adjusting the thickness and quantity of appropriate optical filters. photometric image acquisition hardware adopts the DSP as a core processor to drive the area CCD, to sample, acquire , process and save the image from image sensor, to transmit the image to computer. For real-time performance of transmitting, the hardware system adopts the transmission protocol of USB2.0. The uploaded image will be processed by photometric image analyzing software, and then displayed in real time with detection results. The screen photometric detection technology based on area CCD can detect specifications of the whole screen such as luminance, contrast, onoff ratio and uniformity, breaks the limitation of randomness and incompleteness in current detection technology, exactly and fully reflects the integrated display quality of the whole screen. According to the test results, the accuracy of this system has reached the accuracy level one in China.

  6. Photon-counting gamma camera based on columnar CsI(Tl) optically coupled to a back-illuminated CCD

    PubMed Central

    Miller, Brian W.; Barber, H. Bradford; Barrett, Harrison H.; Chen, Liying; Taylor, Sean J.

    2010-01-01

    Recent advances have been made in a new class of CCD-based, single-photon-counting gamma-ray detectors which offer sub-100 μm intrinsic resolutions.1–7 These detectors show great promise in small-animal SPECT and molecular imaging and exist in a variety of configurations. Typically, a columnar CsI(Tl) scintillator or a radiography screen (Gd2O2S:Tb) is imaged onto the CCD. Gamma-ray interactions are seen as clusters of signal spread over multiple pixels. When the detector is operated in a charge-integration mode, signal spread across pixels results in spatial-resolution degradation. However, if the detector is operated in photon-counting mode, the gamma-ray interaction position can be estimated using either Anger (centroid) estimation or maximum-likelihood position estimation resulting in a substantial improvement in spatial resolution.2 Due to the low-light-level nature of the scintillation process, CCD-based gamma cameras implement an amplification stage in the CCD via electron multiplying (EMCCDs)8–10 or via an image intensifier prior to the optical path.1 We have applied ideas and techniques from previous systems to our high-resolution LumiSPECT detector.11, 12 LumiSPECT is a dual-modality optical/SPECT small-animal imaging system which was originally designed to operate in charge-integration mode. It employs a cryogenically cooled, high-quantum-efficiency, back-illuminated large-format CCD and operates in single-photon-counting mode without any intermediate amplification process. Operating in photon-counting mode, the detector has an intrinsic spatial resolution of 64 μm compared to 134 μm in integrating mode. PMID:20890397

  7. Enhanced performance CCD output amplifier

    DOEpatents

    Dunham, Mark E.; Morley, David W.

    1996-01-01

    A low-noise FET amplifier is connected to amplify output charge from a che coupled device (CCD). The FET has its gate connected to the CCD in common source configuration for receiving the output charge signal from the CCD and output an intermediate signal at a drain of the FET. An intermediate amplifier is connected to the drain of the FET for receiving the intermediate signal and outputting a low-noise signal functionally related to the output charge signal from the CCD. The amplifier is preferably connected as a virtual ground to the FET drain. The inherent shunt capacitance of the FET is selected to be at least equal to the sum of the remaining capacitances.

  8. CCD (charge-coupled device) sensors in synchrotron x-ray detectors

    SciTech Connect

    Strauss, M.G.; Naday, I.; Sherman, I.S.; Kraimer, M.R.; Westbrook, E.M.; Zaluzec, N.J.

    1987-01-01

    The intense photon flux from advanced synchrotron light sources, such as the 7-GeV synchrotron being designed at Argonne, require integrating-type detectors. Charge-coupled devices (CCDs) are well suited as synchrotron x-ray detectors. When irradiated indirectly via a phosphor followed by reducing optics, diffraction patterns of 100 cm/sup 2/ can be imaged on a 2 cm/sup 2/ CCD. With a conversion efficiency of approx.1 CCD electron/x-ray photon, a peak saturation capacity of >10/sup 6/ x rays can be obtained. A programmable CCD controller operating at a clock frequency of 20 MHz has been developed. The readout rate is 5 x 10/sup 6/ pixels/s and the shift rate in the parallel registers is 10/sup 6/ lines/s. The test detector was evaluated in two experiments. In protein crystallography diffraction patterns have been obtained from a lysozyme crystal using a conventional rotating anode x-ray generator. Based on these results we expect to obtain at a synchrotron diffraction images at the rate of approx.1 frame/s or a complete 3-dimensional data set from a single crystal in approx.2 min. 16 refs., 16 figs., 2 tabs.

  9. Charge-Coupled Device (CCD) Trackers For High-Accuracy Guidance Applications

    NASA Astrophysics Data System (ADS)

    Salomon, Phil M.

    1981-02-01

    Recent advances in large area charge-coupled device (CCD) imaging detectors and high-speed microprocessors have prompted the development of a new clss of electro-optical tracking instruments at the Jet Propulsion Labora-tory (JPL). These instruments are designed for standardized NASA-wide usage and are characterized by their extremely high pointing accuracy and stability and performance capabilities which are largely software defined and thus easily adapted to a variety of mission requirements. This paper presents an examination of the methods by which CCD detectors are being incorporated in star tracker instruments and the performance capabilities that can be expected from currently available devices. The multi-function sensor concept, in which a single sensor can function in a variety of guidance applications, is described. Software algorithms designed to provide efficient extraction of guidance information from both point and extended images are also presented. CCD star tracker implementations currently underway at JPL are described, and perfor-mance data obtained during laboratory testing are presented and discussed.

  10. Charge-coupled device /CCD/ trackers for high accuracy guidance applications

    NASA Technical Reports Server (NTRS)

    Salomon, P. M.

    1979-01-01

    Recent advances in large area charge coupled device (CCD) imaging detectors and high speed microprocessors have prompted the development of a new class of electro-optical tracking instruments at the Jet Propulsion Laboratory (JPL). These instruments are designed for standardized NASA-wide usage and are characterized by their extremely high pointing accuracy and stability and performance capabilities which are largely software defined and thus easily adapted to a variety of mission requirements. This paper presents an examination of the methods by which CCD detectors are being incorporated in star tracker instruments and the performance capabilities that can be expected from currently available devices. The multi-function sensor concept, in which a single sensor can function in a variety of guidance applications, is described. Software algorithms designed to provide efficient extraction of guidance information from both point and extended images are also presented. CCD star tracker implementations currently underway at JPL are described, and performance data obtained during laboratory testing is presented and discussed.

  11. AXIOM: Advanced X-ray imaging of the magnetosheath

    NASA Astrophysics Data System (ADS)

    Sembay, S.; Branduardi-Raymont, G.; Eastwood, J. P.; Sibeck, D. G.; Abbey, A.; Brown, P.; Carter, J. A.; Carr, C. M.; Forsyth, C.; Kataria, D.; Kemble, S.; Milan, S.; Owen, C. J.; Read, A. M.; Peacocke, L.; Arridge, C. S.; Coates, A. J.; Collier, M. R.; Cowley, S. W. H.; Fazakerley, A. N.; Fraser, G.; Jones, G. H.; Lallement, R.; Lester, M.; Porter, F. S.; Yeoman, T.

    2012-04-01

    AXIOM (Advanced X-ray Imaging Of the Magnetosphere) is a concept mission which aims to explain how the Earth's magnetosphere responds to the changing impact of the solar wind using a unique method never attempted before; performing wide-field soft X-ray imaging and spectroscopy of the magnetosheath, magnetopause and bow shock at high spatial and temporal resolution. Global imaging of these regions is possible because of the solar wind charge exchange (SWCX) process which produces elevated soft X-ray emission from the interaction of high charge-state solar wind ions with primarily neutral hydrogen in the Earth's exosphere and near-interplanetary space.

  12. The ADIS advanced data acquisition, imaging, and storage system

    SciTech Connect

    Flaherty, J.W.

    1986-01-01

    The design and development of Automated Ultrasonic Scanning Systems (AUSS) by McDonnell Aircraft Company has provided the background for the development of the ADIS advanced data acquisition, imaging, and storage system. The ADIS provides state-of-the-art ultrasonic data processing and imaging features which can be utilized in both laboratory and production line composite evaluation applications. System features, such as, real-time imaging, instantaneous electronic rescanning, multitasking capability, histograms, and cross-sections, provide the tools necessary to inspect and evaluate composite parts quickly and consistently.

  13. AXIOM: Advanced X-Ray Imaging Of the Magnetosheath

    NASA Technical Reports Server (NTRS)

    Sembay, S.; Branduardi-Rayrnont, G.; Eastwood, J. P.; Sibeck, D. G.; Abbey, A.; Brown, P.; Carter, J. A.; Carr, C. M.; Forsyth, C; Kataria, D.; Kemble, S.; Milan, S.; Owen, C. J.; Read, A. M.; Peacocke, L.; Arridge, C. S.; Coates, A. J.; Collier, M. R.; Cowley, S. W. H.; Fazakerley, A. N.; Fraser, G.; Jones, G. H.; Lallement, R.; Lester, M.; Porter, F. S.

    2012-01-01

    AXIOM (Advanced X-ray Imaging Of the Magnetosphere) is a concept mission which aims to explain how the Earth's magnetosphere responds to the changing impact of the solar wind using a unique method never attempted before; performing wide-field soft X-ray imaging and spectroscopy of the magnetosheath. magnetopause and bow shock at high spatial and temporal resolution. Global imaging of these regions is possible because of the solar wind charge exchange (SWCX) process which produces elevated soft X-ray emission from the interaction of high charge-state solar wind ions with primarily neutral hydrogen in the Earth's exosphere and near-interplanetary space.

  14. The Advanced Space Plant Culture Device with Live Imaging Technique

    NASA Astrophysics Data System (ADS)

    Zheng, Weibo; Zhang, Tao; Tong, Guanghui

    The live imaging techniques, including the color and fluorescent imags, are very important and useful for space life science. The advanced space plant culture Device (ASPCD) with live imaging Technique, developed for Chinese Spacecraft, would be introduced in this paper. The ASPCD had two plant experimental chambers. Three cameras (two color cameras and one fluorescent camera) were installed in the two chambers. The fluorescent camera could observe flowering genes, which were labeled by GFP. The lighting, nutrient, temperature controling and water recycling were all independent in each chamber. The ASPCD would beed applied to investigate for the growth and development of the high plant under microgravity conditions on board the Chinese Spacecraft.

  15. In-flight performance of the Japanese Advanced Meteorological Imager

    NASA Astrophysics Data System (ADS)

    Puschell, Jeffrey J.; Osgood, Roderic; Auchter, Joseph; Hurt, W. Todd; Hitomi, Miyamoto; Sasaki, Masayuki; Tahara, Yoshihiko; Tadros, Alfred; Faller, Ken; Mclaren, Mark; Sheffield, Jonathan; Gaiser, John; Kamel, Ahmed; Gunshor, Mathew

    2006-08-01

    The Japanese Advanced Meteorological Imager (JAMI) was developed by Raytheon and delivered to Space Systems/Loral as the Imager Subsystem for Japan's MTSAT-1R satellite. MTSAT-1R was launched from the Tanegashima Space Center on 2005 February 26 and became formally operational on 2005 June 28. This paper compares in-flight performance of JAMI with predictions made before launch. The performance areas discussed include radiometric sensitivity (NEDT and SNR) versus spectral channel, calibration accuracy versus spectral channel derived from comparisons of JAMI and AIRS measurements and image navigation and registration.

  16. X-ray Diffraction and Multi-Frame Phase Contrast Imaging Diagnostics for IMPULSE at the Advanced Photon Source

    SciTech Connect

    Iverson, Adam; Carlson, Carl; Young, Jason; Curtis, Alden; Jensen, Brian; Ramos, Kyle; Yeager, John; Montgomery, David; Fezza, Kamel

    2013-07-08

    The diagnostic needs of any dynamic loading platform present unique technical challenges that must be addressed in order to accurately measure in situ material properties in an extreme environment. The IMPULSE platform (IMPact system for Ultrafast Synchrotron Experiments) at the Advanced Photon Source (APS) is no exception and, in fact, may be more challenging, as the imaging diagnostics must be synchronized to both the experiment and the 60 ps wide x-ray bunches produced at APS. The technical challenges of time-resolved x-ray diffraction imaging and high-resolution multi-frame phase contrast imaging (PCI) are described in this paper. Example data from recent IMPULSE experiments are shown to illustrate the advances and evolution of these diagnostics with a focus on comparing the performance of two intensified CCD cameras and their suitability for multi-frame PCI. The continued development of these diagnostics is fundamentally important to IMPULSE and many other loading platforms and will benefit future facilities such as the Dynamic Compression Sector at APS and MaRIE at Los Alamos National Laboratory.

  17. Imaging for understanding speech communication: Advances and challenges

    NASA Astrophysics Data System (ADS)

    Narayanan, Shrikanth

    2005-04-01

    Research in speech communication has relied on a variety of instrumentation methods to illuminate details of speech production and perception. One longstanding challenge has been the ability to examine real-time changes in the shaping of the vocal tract; a goal that has been furthered by imaging techniques such as ultrasound, movement tracking, and magnetic resonance imaging. The spatial and temporal resolution afforded by these techniques, however, has limited the scope of the investigations that could be carried out. In this talk, we focus on some recent advances in magnetic resonance imaging that allow us to perform near real-time investigations on the dynamics of vocal tract shaping during speech. Examples include Demolin et al. (2000) (4-5 images/second, ultra-fast turbo spin echo) and Mady et al. (2001,2002) (8 images/second, T1 fast gradient echo). A recent study by Narayanan et al. (2004) that used a spiral readout scheme to accelerate image acquisition has allowed for image reconstruction rates of 24 images/second. While these developments offer exciting prospects, a number of challenges lie ahead, including: (1) improving image acquisition protocols, hardware for enhancing signal-to-noise ratio, and optimizing spatial sampling; (2) acquiring quality synchronized audio; and (3) analyzing and modeling image data including cross-modality registration. [Work supported by NIH and NSF.

  18. Driving a CCD with two ASICs: CABAC and ASPIC

    NASA Astrophysics Data System (ADS)

    Juramy, Claire; Antilogus, Pierre; Bailly, Philippe; Baumont, Sylvain; Dhellot, Marc; El Berni, Mowafak; Jeglot, Jimmy; Lebbolo, Hervé; Martin, David; Qureshi, Aftab; Russo, Stefano; Terront, Diego; Tocut, Vanessa; Vallerand, Philippe

    2014-07-01

    We present two lines of ASICs dedicated to the control and readout of CCD sensors. The CABAC (Clocks And Biases ASIC for CCDs) provides all required bias voltages and clocks. The ASPIC (Analog Signal Processing Integrated Circuit) processes 8 CCD output channels: amplification, Correlated Double Sampling, conversion to differential signal. Both chips are highly configurable in order to fulfill a wide range of astronomical CCD readout needs, from fast readout of wide-field imaging arrays to slower speeds and higher gains for spectroscopy. Their sizes and temperature ranges allow to integrate them in-cryostat, close to the sensors, and they offer diagnostic capabilities to assist the integration. In addition to extensive stand-alone tests, these chips are integrated in the LSST REB (Raft Electronics Board), and have been tested driving the E2V prototype CCD for the LSST focal plane.

  19. Advanced technology development for image gathering, coding, and processing

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O.

    1990-01-01

    Three overlapping areas of research activities are presented: (1) Information theory and optimal filtering are extended to visual information acquisition and processing. The goal is to provide a comprehensive methodology for quantitatively assessing the end-to-end performance of image gathering, coding, and processing. (2) Focal-plane processing techniques and technology are developed to combine effectively image gathering with coding. The emphasis is on low-level vision processing akin to the retinal processing in human vision. (3) A breadboard adaptive image-coding system is being assembled. This system will be used to develop and evaluate a number of advanced image-coding technologies and techniques as well as research the concept of adaptive image coding.

  20. Establishing advanced practice for medical imaging in New Zealand

    PubMed Central

    Yielder, Jill; Young, Adrienne; Park, Shelley; Coleman, Karen

    2014-01-01

    IntroductionThis article presents the outcome and recommendations following the second stage of a role development project conducted on behalf of the New Zealand Institute of Medical Radiation Technology (NZIMRT). The study sought to support the development of profiles and criteria that may be used to formulate Advanced Scopes of Practice for the profession. It commenced in 2011, following on from initial research that occurred between 2005 and 2008 investigating role development and a possible career structure for medical radiation technologists (MRTs) in New Zealand (NZ). MethodsThe study sought to support the development of profiles and criteria that could be used to develop Advanced Scopes of Practice for the profession through inviting 12 specialist medical imaging groups in NZ to participate in a survey. ResultsFindings showed strong agreement on potential profiles and on generic criteria within them; however, there was less agreement on specific skills criteria within specialist areas. ConclusionsThe authors recommend that one Advanced Scope of Practice be developed for Medical Imaging, with the establishment of generic and specialist criteria. Systems for approval of the overall criteria package for any individual Advanced Practitioner (AP) profile, audit and continuing professional development requirements need to be established by the Medical Radiation Technologists Board (MRTB) to meet the local needs of clinical departments. It is further recommended that the NZIMRT and MRTB promote and support the need for an AP pathway for medical imaging in NZ. PMID:26229631

  1. Establishing advanced practice for medical imaging in New Zealand

    SciTech Connect

    Yielder, Jill; Young, Adrienne; Park, Shelley; Coleman, Karen

    2014-02-15

    Introduction: This article presents the outcome and recommendations following the second stage of a role development project conducted on behalf of the New Zealand Institute of Medical Radiation Technology (NZIMRT). The study sought to support the development of profiles and criteria that may be used to formulate Advanced Scopes of Practice for the profession. It commenced in 2011, following on from initial research that occurred between 2005 and 2008 investigating role development and a possible career structure for medical radiation technologists (MRTs) in New Zealand (NZ). Methods: The study sought to support the development of profiles and criteria that could be used to develop Advanced Scopes of Practice for the profession through inviting 12 specialist medical imaging groups in NZ to participate in a survey. Results: Findings showed strong agreement on potential profiles and on generic criteria within them; however, there was less agreement on specific skills criteria within specialist areas. Conclusions: The authors recommend that one Advanced Scope of Practice be developed for Medical Imaging, with the establishment of generic and specialist criteria. Systems for approval of the overall criteria package for any individual Advanced Practitioner (AP) profile, audit and continuing professional development requirements need to be established by the Medical Radiation Technologists Board (MRTB) to meet the local needs of clinical departments. It is further recommended that the NZIMRT and MRTB promote and support the need for an AP pathway for medical imaging in NZ.

  2. Riprese CCD della chioma interna della cometa Ikeya-Zhang

    NASA Astrophysics Data System (ADS)

    Comolli, Lorenzo

    2003-03-01

    During the period of maximum brightness of comet Ikeya-Zhang we acquired many unsaturated CCD images thanks to a period of good weather. The series of images of about 2 weeks can be animated so that changes in the inner coma are made evident. Elaborations with Larson-Sekanina filter and masking filters evidence details like concentric halos, jets and shells.

  3. CCD centroiding experiment for JASMINE and ILOM

    NASA Astrophysics Data System (ADS)

    Yano, Taihei; Araki, Hiroshi; Gouda, Naoteru; Kobayashi, Yukiyasu; Tsujimoto, Takuji; Nakajima, Tadashi; Kawano, Nobuyuki; Tazawa, Seiichi; Yamada, Yoshiyuki; Hanada, Hideo; Asari, Kazuyoshi; Tsuruta, Seiitsu

    2006-06-01

    JASMINE and ILOM are space missions which are in progress at the National Astronomical Observatory of Japan. These two projects need a common astrometric technique to obtain precise positions of star images on solid state detectors to accomplish the objectives. We have carried out measurements of centroid of artificial star images on a CCD to investigate the accuracy of the positions of the stars, using an algorithm for estimating them from photon weighted means of the stars. We find that the accuracy of the star positions reaches 1/300 pixel for one measurement. We also measure positions of stars, using an algorithm for correcting the distorted optical image. Finally, we find that the accuracy of the measurement for the positions of the stars from the strongly distorted image is under 1/150 pixel for one measurement.

  4. Challenges and recent advances in mass spectrometric imaging of neurotransmitters

    PubMed Central

    Gemperline, Erin; Chen, Bingming; Li, Lingjun

    2014-01-01

    Mass spectrometric imaging (MSI) is a powerful tool that grants the ability to investigate a broad mass range of molecules, from small molecules to large proteins, by creating detailed distribution maps of selected compounds. To date, MSI has demonstrated its versatility in the study of neurotransmitters and neuropeptides of different classes toward investigation of neurobiological functions and diseases. These studies have provided significant insight in neurobiology over the years and current technical advances are facilitating further improvements in this field. neurotransmitters, focusing specifically on the challenges and recent Herein, we advances of MSI of neurotransmitters. PMID:24568355

  5. Recent advances in image-guided targeted prostate biopsy.

    PubMed

    Brown, Anna M; Elbuluk, Osama; Mertan, Francesca; Sankineni, Sandeep; Margolis, Daniel J; Wood, Bradford J; Pinto, Peter A; Choyke, Peter L; Turkbey, Baris

    2015-08-01

    Prostate cancer is a common malignancy in the United States that results in over 30,000 deaths per year. The current state of prostate cancer diagnosis, based on PSA screening and sextant biopsy, has been criticized for both overdiagnosis of low-grade tumors and underdiagnosis of clinically significant prostate cancers (Gleason score ≥7). Recently, image guidance has been added to perform targeted biopsies of lesions detected on multi-parametric magnetic resonance imaging (mpMRI) scans. These methods have improved the ability to detect clinically significant cancer, while reducing the diagnosis of low-grade tumors. Several approaches have been explored to improve the accuracy of image-guided targeted prostate biopsy, including in-bore MRI-guided, cognitive fusion, and MRI/transrectal ultrasound fusion-guided biopsy. This review will examine recent advances in these image-guided targeted prostate biopsy techniques. PMID:25596716

  6. Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection

    PubMed Central

    Sinharay, Sanhita; Pagel, Mark D.

    2016-01-01

    Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new capabilities for biomarker detection through molecular imaging. MRI contrast agents based on the T2 exchange mechanism have more recently expanded the armamentarium of agents for molecular imaging. Compared with T1 and T2* agents, T2 exchange agents have a slower chemical exchange rate, which improves the ability to design these MRI contrast agents with greater specificity for detecting the intended biomarker. MRI contrast agents that are detected through chemical exchange saturation transfer (CEST) have even slower chemical exchange rates. Another emerging class of MRI contrast agents uses hyperpolarized 13C to detect the agent with outstanding sensitivity. These hyperpolarized 13C agents can be used to track metabolism and monitor characteristics of the tissue microenvironment. Together, these various MRI contrast agents provide excellent opportunities to develop molecular imaging for biomarker detection. PMID:27049630

  7. Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection.

    PubMed

    Sinharay, Sanhita; Pagel, Mark D

    2016-06-12

    Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new capabilities for biomarker detection through molecular imaging. MRI contrast agents based on the T2 exchange mechanism have more recently expanded the armamentarium of agents for molecular imaging. Compared with T1 and T2* agents, T2 exchange agents have a slower chemical exchange rate, which improves the ability to design these MRI contrast agents with greater specificity for detecting the intended biomarker. MRI contrast agents that are detected through chemical exchange saturation transfer (CEST) have even slower chemical exchange rates. Another emerging class of MRI contrast agents uses hyperpolarized (13)C to detect the agent with outstanding sensitivity. These hyperpolarized (13)C agents can be used to track metabolism and monitor characteristics of the tissue microenvironment. Together, these various MRI contrast agents provide excellent opportunities to develop molecular imaging for biomarker detection. PMID:27049630

  8. Advanced hyperspectral video imaging system using Amici prism.

    PubMed

    Feng, Jiao; Fang, Xiaojing; Cao, Xun; Ma, Chenguang; Dai, Qionghai; Zhu, Hongbo; Wang, Yongjin

    2014-08-11

    In this paper, we propose an advanced hyperspectral video imaging system (AHVIS), which consists of an objective lens, an occlusion mask, a relay lens, an Amici prism and two cameras. An RGB camera is used for spatial reading and a gray scale camera is used for measuring the scene with spectral information. The objective lens collects more light energy from the observed scene and images the scene on an occlusion mask, which subsamples the image of the observed scene. Then, the subsampled image is sent to the gray scale camera through the relay lens and the Amici prism. The Amici prism that is used to realize spectral dispersion along the optical path reduces optical distortions and offers direct view of the scene. The main advantages of the proposed system are improved light throughput and less optical distortion. Furthermore, the presented configuration is more compact, robust and practicable. PMID:25321019

  9. Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection

    NASA Astrophysics Data System (ADS)

    Sinharay, Sanhita; Pagel, Mark D.

    2016-06-01

    Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new capabilities for biomarker detection through molecular imaging. MRI contrast agents based on the T2 exchange mechanism have more recently expanded the armamentarium of agents for molecular imaging. Compared with T1 and T2* agents, T2 exchange agents have a slower chemical exchange rate, which improves the ability to design these MRI contrast agents with greater specificity for detecting the intended biomarker. MRI contrast agents that are detected through chemical exchange saturation transfer (CEST) have even slower chemical exchange rates. Another emerging class of MRI contrast agents uses hyperpolarized 13C to detect the agent with outstanding sensitivity. These hyperpolarized 13C agents can be used to track metabolism and monitor characteristics of the tissue microenvironment. Together, these various MRI contrast agents provide excellent opportunities to develop molecular imaging for biomarker detection.

  10. Advanced biologically plausible algorithms for low-level image processing

    NASA Astrophysics Data System (ADS)

    Gusakova, Valentina I.; Podladchikova, Lubov N.; Shaposhnikov, Dmitry G.; Markin, Sergey N.; Golovan, Alexander V.; Lee, Seong-Whan

    1999-08-01

    At present, in computer vision, the approach based on modeling the biological vision mechanisms is extensively developed. However, up to now, real world image processing has no effective solution in frameworks of both biologically inspired and conventional approaches. Evidently, new algorithms and system architectures based on advanced biological motivation should be developed for solution of computational problems related to this visual task. Basic problems that should be solved for creation of effective artificial visual system to process real world imags are a search for new algorithms of low-level image processing that, in a great extent, determine system performance. In the present paper, the result of psychophysical experiments and several advanced biologically motivated algorithms for low-level processing are presented. These algorithms are based on local space-variant filter, context encoding visual information presented in the center of input window, and automatic detection of perceptually important image fragments. The core of latter algorithm are using local feature conjunctions such as noncolinear oriented segment and composite feature map formation. Developed algorithms were integrated into foveal active vision model, the MARR. It is supposed that proposed algorithms may significantly improve model performance while real world image processing during memorizing, search, and recognition.

  11. Advanced imaging techniques for the detection of breast cancer.

    PubMed

    Jochelson, Maxine

    2012-01-01

    Mammography is the only breast imaging examination that has been shown to reduce breast cancer mortality. Population-based sensitivity is 75% to 80%, but sensitivity in high-risk women with dense breasts is only in the range of 50%. Breast ultrasound and contrast-enhanced breast magnetic resonance imaging (MRI) have become additional standard modalities used in the diagnosis of breast cancer. In high-risk women, ultrasound is known to detect approximately four additional cancers per 1,000 women. MRI is exquisitely sensitive for the detection of breast cancer. In high-risk women, it finds an additional four to five cancers per 100 women. However, both ultrasound and MRI are also known to lead to a large number of additional benign biopsies and short-term follow-up examinations. Many new breast imaging tools have improved and are being developed to improve on our current ability to diagnose early-stage breast cancer. These can be divided into two groups. The first group is those that are advances in current techniques, which include digital breast tomosynthesis and contrast-enhanced mammography and ultrasound with elastography or microbubbles. The other group includes new breast imaging platforms such as breast computed tomography (CT) scanning and radionuclide breast imaging. These are exciting advances. However, in this era of cost and radiation containment, it is imperative to look at all of them objectively to see which will provide clinically relevant additional information. PMID:24451711

  12. Advanced Imaging Modalities in the Detection of Cerebral Vasospasm

    PubMed Central

    Mills, Jena N.; Mehta, Vivek; Russin, Jonathan; Amar, Arun P.; Rajamohan, Anandh; Mack, William J.

    2013-01-01

    The pathophysiology of cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH) is complex and is not entirely understood. Mechanistic insights have been gained through advances in the capabilities of diagnostic imaging. Core techniques have focused on the assessment of vessel caliber, tissue metabolism, and/or regional perfusion parameters. Advances in imaging have provided clinicians with a multifaceted approach to assist in the detection of cerebral vasospasm and the diagnosis of delayed ischemic neurologic deficits (DIND). However, a single test or algorithm with broad efficacy remains elusive. This paper examines both anatomical and physiological imaging modalities applicable to post-SAH vasospasm and offers a historical background. We consider cerebral blood flow velocities measured by Transcranial Doppler Ultrasonography (TCD). Structural imaging techniques, including catheter-based Digital Subtraction Angiography (DSA), CT Angiography (CTA), and MR Angiography (MRA), are reviewed. We examine physiologic assessment by PET, HMPAO SPECT, 133Xe Clearance, Xenon-Enhanced CT (Xe/CT), Perfusion CT (PCT), and Diffusion-Weighted/MR Perfusion Imaging. Comparative advantages and limitations are discussed. PMID:23476766

  13. Labeling of virus components for advanced, quantitative imaging analyses.

    PubMed

    Sakin, Volkan; Paci, Giulia; Lemke, Edward A; Müller, Barbara

    2016-07-01

    In recent years, investigation of virus-cell interactions has moved from ensemble measurements to imaging analyses at the single-particle level. Advanced fluorescence microscopy techniques provide single-molecule sensitivity and subdiffraction spatial resolution, allowing observation of subviral details and individual replication events to obtain detailed quantitative information. To exploit the full potential of these techniques, virologists need to employ novel labeling strategies, taking into account specific constraints imposed by viruses, as well as unique requirements of microscopic methods. Here, we compare strengths and limitations of various labeling methods, exemplify virological questions that were successfully addressed, and discuss challenges and future potential of novel approaches in virus imaging. PMID:26987299

  14. Advances in brain imaging: a new ethical challenge.

    PubMed

    Alfano, B; Brunetti, A

    1997-01-01

    Technical advances in the past 25 years permitted substantial advances in the neuroimaging field, expanding the diagnostic and research potentials and significantly reducing the use of old invasive imaging techniques for research purposes. The safer procedures now available allow acquisition of reference data, morphological assessment and functional characterisation from healthy volunteers. However, enrollment of volunteers is still a sensitive ethical issue. Ethical problems related to informed consent, for both research and diagnostic procedures, in patients with neuropsychiatric disorders represent an additional crucial issue. Furthermore, with both functional and structural neuroimaging studies, there is a theoretical risk of violation of individual privacy. Research in the neuroimaging field should tend to increase the amount of information obtained through appropriate post-processing procedures, including multimodality image fusion, and to limit stress and discomfort. PMID:9616958

  15. Driving techniques for high frame rate CCD camera

    NASA Astrophysics Data System (ADS)

    Guo, Weiqiang; Jin, Longxu; Xiong, Jingwu

    2008-03-01

    This paper describes a high-frame rate CCD camera capable of operating at 100 frames/s. This camera utilizes Kodak KAI-0340, an interline transfer CCD with 640(vertical)×480(horizontal) pixels. Two output ports are used to read out CCD data and pixel rates approaching 30 MHz. Because of its reduced effective opacity of vertical charge transfer registers, interline transfer CCD can cause undesired image artifacts, such as random white spots and smear generated in the registers. To increase frame rate, a kind of speed-up structure has been incorporated inside KAI-0340, then it is vulnerable to a vertical stripe effect. The phenomena which mentioned above may severely impair the image quality. To solve these problems, some electronic methods of eliminating these artifacts are adopted. Special clocking mode can dump the unwanted charge quickly, then the fast readout of the images, cleared of smear, follows immediately. Amplifier is used to sense and correct delay mismatch between the dual phase vertical clock pulses, the transition edges become close to coincident, so vertical stripes disappear. Results obtained with the CCD camera are shown.

  16. Advanced Imaging for Biopsy Guidance in Primary Brain Tumors

    PubMed Central

    Tsiouris, Apostolos J; Ramakrishna, Rohan

    2016-01-01

    Accurate glioma sampling is required for diagnosis and establishing eligibility for relevant clinical trials. MR-based perfusion and spectroscopy sequences supplement conventional MR in noninvasively predicting the areas of highest tumor grade for biopsy. We report the case of a patient with gliomatosis cerebri and multifocal patchy enhancement in whom the combination of advanced and conventional imaging attributes successfully guided a diagnostic biopsy. PMID:27014538

  17. Advanced indium antimonide monolithic charge coupled infrared imaging arrays

    NASA Technical Reports Server (NTRS)

    Koch, T. L.; Merilainen, C. A.; Thom, R. D.

    1981-01-01

    The continued process development of SiO2 insulators for use in advanced InSb monolithic charge coupled infrared imaging arrays is described. Specific investigations into the use of plasma enhanced chemical vapor deposited (PECVD) SiO2 as a gate insulator for InSb charge coupled devices is discussed, as are investigations of other chemical vapor deposited SiO2 materials.

  18. Anti-Stokes effect CCD camera and SLD based optical coherence tomography for full-field imaging in the 1550nm region

    NASA Astrophysics Data System (ADS)

    Kredzinski, Lukasz; Connelly, Michael J.

    2012-06-01

    Full-field Optical coherence tomography is an en-face interferometric imaging technology capable of carrying out high resolution cross-sectional imaging of the internal microstructure of an examined specimen in a non-invasive manner. The presented system is based on competitively priced optical components available at the main optical communications band located in the 1550 nm region. It consists of a superluminescent diode and an anti-stokes imaging device. The single mode fibre coupled SLD was connected to a multi-mode fibre inserted into a mode scrambler to obtain spatially incoherent illumination, suitable for OCT wide-field modality in terms of crosstalk suppression and image enhancement. This relatively inexpensive system with moderate resolution of approximately 24um x 12um (axial x lateral) was constructed to perform a 3D cross sectional imaging of a human tooth. To our knowledge this is the first 1550 nm full-field OCT system reported.

  19. Advances in Magnetic Resonance Imaging of the Skull Base

    PubMed Central

    Kirsch, Claudia F.E.

    2014-01-01

    Introduction Over the past 20 years, magnetic resonance imaging (MRI) has advanced due to new techniques involving increased magnetic field strength and developments in coils and pulse sequences. These advances allow increased opportunity to delineate the complex skull base anatomy and may guide the diagnosis and treatment of the myriad of pathologies that can affect the skull base. Objectives The objective of this article is to provide a brief background of the development of MRI and illustrate advances in skull base imaging, including techniques that allow improved conspicuity, characterization, and correlative physiologic assessment of skull base pathologies. Data Synthesis Specific radiographic illustrations of increased skull base conspicuity including the lower cranial nerves, vessels, foramina, cerebrospinal fluid (CSF) leaks, and effacement of endolymph are provided. In addition, MRIs demonstrating characterization of skull base lesions, such as recurrent cholesteatoma versus granulation tissue or abscess versus tumor, are also provided as well as correlative clinical findings in CSF flow studies in a patient pre- and post-suboccipital decompression for a Chiari I malformation. Conclusions This article illustrates MRI radiographic advances over the past 20 years, which have improved clinicians' ability to diagnose, define, and hopefully improve the treatment and outcomes of patients with underlying skull base pathologies. PMID:25992137

  20. Ground-based CCD astrometry with wide field imagers. III. WFI@2.2m proper-motion catalog of the globular cluster ω Centauri

    NASA Astrophysics Data System (ADS)

    Bellini, A.; Piotto, G.; Bedin, L. R.; Anderson, J.; Platais, I.; Momany, Y.; Moretti, A.; Milone, A. P.; Ortolani, S.

    2009-01-01

    Context: ω Centauri is the most well studied Galactic Globular Cluster because of its numerous puzzling features: significant dispersion in metallicity, multiple populations, triple main-sequence, horizontal branch morphology, He-rich population(s), and extended star-formation history. Intensive spectroscopic follow-up observing campaigns targeting stars at different positions in the color-magnitude diagram promises to clarify some of these peculiarities. Aims: To be able to target cluster members reliably during spectroscopic surveys and both spatial and radial distributions in the cluster outskirts without including field stars, a high quality proper-motion catalog of ω Cen and membership probability determination are required. The only available wide field proper-motion catalog of ω Cen is derived from photographic plates, and only for stars brighter than B~16. Using ESO archive data, we create a new, CCD-based, proper-motion catalog for this cluster, extending to B~20. Methods: We used high precision astrometric software developed specifically for data acquired by WFI@2.2m telescope and presented in the first paper of this series. We demonstrated previously that a 7 mas astrometric precision level can be achieved with this telescope and camera for well exposed stars in a single exposure, assuming an empirical PSF and a local transformation approach in measuring star displacements. Results: We achieved a good cluster-field separation with a temporal base-line of only four years. We corrected our photometry for sky-concentration effects. We provide calibrated photometry for UBVR_CIC wide-band data plus narrow-band filter data centered on Hα for almost 360 000 stars. We confirm that the ω Cen metal-poor and metal-rich components have the same proper motion, and demonstrate that the metal-intermediate component in addition exhibits the same mean motion as the other RGB stars. We provide membership probability determinations for published ω Cen variable star

  1. Parallel hardware architecture for CCD-mosaic digital mammography

    NASA Astrophysics Data System (ADS)

    Smith, Scott T.; Kim, Hyunkeun; Swarnakar, Vivek; Jeong, Myoungki; Wobschall, Darold C.

    1998-06-01

    The development of an efficient parallel hardware architecture suitable for CCD-mosaic digital mammography has been accomplished. This paper presents this architecture including both the analog and digital portions of the imaging hardware. A two dimensional array of CCD sensors are used to capture the mammographic image synchronously and simultaneously. Each CCD's analog signal is converted to a 12 bits/pixel digital value through an array of high speed analog-to-digital converters. A parallel array of mesh connected TMS320C40 DSP processors then takes in the digital image data simultaneously. The DSP's are used to precisely register the mosaic of individual images to form the final large format digital mammogram. Also, they are used to control CCD characteristics and parallel data transport to the viewing workstation. One master DSP is located on the workstation's PCI bus which controls the parallel DSP array and collects compressed image data through a 60MB/s port. Since all computations are performed in parallel using local memory on each DSP, the overall acquisition, image registration, and transmission to display of the final mammogram is performed in less than 30 seconds. This allows the physician to perform a preliminary observation of the patient's mammogram.

  2. Interline Transfer CCD Camera for Gated Broadband Coherent Anti-Stokes Raman-Scattering Measurements.

    PubMed

    Roy, S; Ray, G; Lucht, R P

    2001-11-20

    Use of an interline transfer CCD camera for the acquisition of broadband coherent anti-Stokes Raman-scattering (CARS) spectra is demonstrated. The interline transfer CCD has alternating columns of imaging and storage pixels that allow one to acquire two successive images by shifting the first image in the storage pixels and immediately acquiring the second image. We have used this dual-image mode for gated CARS measurements by acquiring a CARS spectral image and shifting it rapidly from the imaging pixel columns to the storage pixel columns. We have demonstrated the use of this dual-image mode for gated single-laser-shot measurement of hydrogen and nitrogen CARS spectra at room temperature and in atmospheric pressure flames. The performance of the interline transfer CCD for these CARS measurements is compared directly with the performance of a back-illuminated unintensified CCD camera. PMID:18364895

  3. Advances in imaging secondary ion mass spectrometry for biological samples

    SciTech Connect

    Boxer, Steven G.; Kraft, Mary L.; Weber, Peter K.

    2008-12-16

    Imaging mass spectrometry combines the power of mass spectrometry to identify complex molecules based on mass with sample imaging. Recent advances in secondary ion mass spectrometry have improved sensitivity and spatial resolution, so that these methods have the potential to bridge between high-resolution structures obtained by X-ray crystallography and cyro-electron microscopy and ultrastructure visualized by conventional light microscopy. Following background information on the method and instrumentation, we address the key issue of sample preparation. Because mass spectrometry is performed in high vacuum, it is essential to preserve the lateral organization of the sample while removing bulk water, and this has been a major barrier for applications to biological systems. Furthermore, recent applications of imaging mass spectrometry to cell biology, microbial communities, and biosynthetic pathways are summarized briefly, and studies of biological membrane organization are described in greater depth.

  4. Imaging spectroscopic analysis at the Advanced Light Source

    SciTech Connect

    MacDowell, A. A.; Warwick, T.; Anders, S.; Lamble, G.M.; Martin, M.C.; McKinney, W.R.; Padmore, H.A.

    1999-05-12

    One of the major advances at the high brightness third generation synchrotrons is the dramatic improvement of imaging capability. There is a large multi-disciplinary effort underway at the ALS to develop imaging X-ray, UV and Infra-red spectroscopic analysis on a spatial scale from. a few microns to 10nm. These developments make use of light that varies in energy from 6meV to 15KeV. Imaging and spectroscopy are finding applications in surface science, bulk materials analysis, semiconductor structures, particulate contaminants, magnetic thin films, biology and environmental science. This article is an overview and status report from the developers of some of these techniques at the ALS. The following table lists all the currently available microscopes at the. ALS. This article will describe some of the microscopes and some of the early applications.

  5. Advances in imaging secondary ion mass spectrometry for biological samples

    DOE PAGESBeta

    Boxer, Steven G.; Kraft, Mary L.; Weber, Peter K.

    2008-12-16

    Imaging mass spectrometry combines the power of mass spectrometry to identify complex molecules based on mass with sample imaging. Recent advances in secondary ion mass spectrometry have improved sensitivity and spatial resolution, so that these methods have the potential to bridge between high-resolution structures obtained by X-ray crystallography and cyro-electron microscopy and ultrastructure visualized by conventional light microscopy. Following background information on the method and instrumentation, we address the key issue of sample preparation. Because mass spectrometry is performed in high vacuum, it is essential to preserve the lateral organization of the sample while removing bulk water, and this hasmore » been a major barrier for applications to biological systems. Furthermore, recent applications of imaging mass spectrometry to cell biology, microbial communities, and biosynthetic pathways are summarized briefly, and studies of biological membrane organization are described in greater depth.« less

  6. Red Fluorescent Proteins: Advanced Imaging Applications and Future Design

    PubMed Central

    Shcherbakova, Daria M.; Subach, Oksana M.; Verkhusha, Vladislav V.

    2015-01-01

    In the past few years a large series of the advanced red-shifted fluorescent proteins (RFPs) has been developed. These enhanced RFPs provide new possibilities to study biological processes at the levels ranging from single molecules to whole organisms. Herein the relationship between the properties of the RFPs of different phenotypes and their applications to various imaging techniques are described. Existing and emerging imaging approaches are discussed for conventional RFPs, far-red FPs, RFPs with a large Stokes shift, fluorescent timers, irreversibly photoactivatable and reversibly photo-switchable RFPs. Advantages and limitations of specific RFPs for each technique are presented. Recent progress in understanding the chemical transformations of red chromophores allows the future RFP phenotypes and their respective novel imaging applications to be foreseen. PMID:22851529

  7. Advanced gastrointestinal endoscopic imaging for inflammatory bowel diseases

    PubMed Central

    Tontini, Gian Eugenio; Rath, Timo; Neumann, Helmut

    2016-01-01

    Gastrointestinal luminal endoscopy is of paramount importance for diagnosis, monitoring and dysplasia surveillance in patients with both, Crohn’s disease and ulcerative colitis. Moreover, with the recent recognition that mucosal healing is directly linked to the clinical outcome of patients with inflammatory bowel disorders, a growing demand exists for the precise, timely and detailed endoscopic assessment of superficial mucosal layer. Further, the novel field of molecular imaging has tremendously expanded the clinical utility and applications of modern endoscopy, now encompassing not only diagnosis, surveillance, and treatment but also the prediction of individual therapeutic responses. Within this review, we describe how novel endoscopic approaches and advanced endoscopic imaging methods such as high definition and high magnification endoscopy, dye-based and dye-less chromoendoscopy, confocal laser endomicroscopy, endocytoscopy and molecular imaging now allow for the precise and ultrastructural assessment of mucosal inflammation and describe the potential of these techniques for dysplasia detection. PMID:26811662

  8. CCD centroiding analysis for Nano-JASMINE observation data

    NASA Astrophysics Data System (ADS)

    Niwa, Yoshito; Yano, Taihei; Araki, Hiroshi; Gouda, Naoteru; Kobayashi, Yukiyasu; Yamada, Yoshiyuki; Tazawa, Seiichi; Hanada, Hideo

    2010-07-01

    Nano-JASMINE is a very small satellite mission for global space astrometry with milli-arcsecond accuracy, which will be launched in 2011. In this mission, centroids of stars in CCD image frames are estimated with sub-pixel accuracy. In order to realize such a high precision centroiding an algorithm utilizing a least square method is employed. One of the advantages is that centroids can be calculated without explicit assumption of the point spread functions of stars. CCD centroiding experiment has been performed to investigate whether this data analysis is available, and centroids of artificial star images on a CCD are determined with a precision of less than 0.001 pixel. This result indicates parallaxes of stars within 300 pc from Sun can be observed in Nano-JASMINE.

  9. Printed circuit board for a CCD camera head

    DOEpatents

    Conder, Alan D.

    2002-01-01

    A charge-coupled device (CCD) camera head which can replace film for digital imaging of visible light, ultraviolet radiation, and soft to penetrating x-rays, such as within a target chamber where laser produced plasmas are studied. The camera head is small, capable of operating both in and out of a vacuum environment, and is versatile. The CCD camera head uses PC boards with an internal heat sink connected to the chassis for heat dissipation, which allows for close (0.04" for example) stacking of the PC boards. Integration of this CCD camera head into existing instrumentation provides a substantial enhancement of diagnostic capabilities for studying high energy density plasmas, for a variety of military industrial, and medical imaging applications.

  10. Advances in Spectral-Spatial Classification of Hyperspectral Images

    NASA Technical Reports Server (NTRS)

    Fauvel, Mathieu; Tarabalka, Yuliya; Benediktsson, Jon Atli; Chanussot, Jocelyn; Tilton, James C.

    2012-01-01

    Recent advances in spectral-spatial classification of hyperspectral images are presented in this paper. Several techniques are investigated for combining both spatial and spectral information. Spatial information is extracted at the object (set of pixels) level rather than at the conventional pixel level. Mathematical morphology is first used to derive the morphological profile of the image, which includes characteristics about the size, orientation and contrast of the spatial structures present in the image. Then the morphological neighborhood is defined and used to derive additional features for classification. Classification is performed with support vector machines using the available spectral information and the extracted spatial information. Spatial post-processing is next investigated to build more homogeneous and spatially consistent thematic maps. To that end, three presegmentation techniques are applied to define regions that are used to regularize the preliminary pixel-wise thematic map. Finally, a multiple classifier system is defined to produce relevant markers that are exploited to segment the hyperspectral image with the minimum spanning forest algorithm. Experimental results conducted on three real hyperspectral images with different spatial and spectral resolutions and corresponding to various contexts are presented. They highlight the importance of spectral-spatial strategies for the accurate classification of hyperspectral images and validate the proposed methods.

  11. Diagnostic imaging advances in murine models of colitis

    PubMed Central

    Brückner, Markus; Lenz, Philipp; Mücke, Marcus M; Gohar, Faekah; Willeke, Peter; Domagk, Dirk; Bettenworth, Dominik

    2016-01-01

    Inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis are chronic-remittent inflammatory disorders of the gastrointestinal tract still evoking challenging clinical diagnostic and therapeutic situations. Murine models of experimental colitis are a vital component of research into human IBD concerning questions of its complex pathogenesis or the evaluation of potential new drugs. To monitor the course of colitis, to the present day, classical parameters like histological tissue alterations or analysis of mucosal cytokine/chemokine expression often require euthanasia of animals. Recent advances mean revolutionary non-invasive imaging techniques for in vivo murine colitis diagnostics are increasingly available. These novel and emerging imaging techniques not only allow direct visualization of intestinal inflammation, but also enable molecular imaging and targeting of specific alterations of the inflamed murine mucosa. For the first time, in vivo imaging techniques allow for longitudinal examinations and evaluation of intra-individual therapeutic response. This review discusses the latest developments in the different fields of ultrasound, molecularly targeted contrast agent ultrasound, fluorescence endoscopy, confocal laser endomicroscopy as well as tomographic imaging with magnetic resonance imaging, computed tomography and fluorescence-mediated tomography, discussing their individual limitations and potential future diagnostic applications in the management of human patients with IBD. PMID:26811642

  12. Developments in the EM-CCD camera for OGRE

    NASA Astrophysics Data System (ADS)

    Tutt, James H.; McEntaffer, Randall L.; DeRoo, Casey; Schultz, Ted; Miles, Drew M.; Zhang, William; Murray, Neil J.; Holland, Andrew D.; Cash, Webster; Rogers, Thomas; O'Dell, Steve; Gaskin, Jessica; Kolodziejczak, Jeff; Evagora, Anthony M.; Holland, Karen; Colebrook, David

    2014-07-01

    The Off-plane Grating Rocket Experiment (OGRE) is a sub-orbital rocket payload designed to advance the development of several emerging technologies for use on space missions. The payload consists of a high resolution soft X-ray spectrometer based around an optic made from precision cut and ground, single crystal silicon mirrors, a module of off-plane gratings and a camera array based around Electron Multiplying CCD (EM-CCD) technology. This paper gives an overview of OGRE with emphasis on the detector array; specifically this paper will address the reasons that EM-CCDs are the detector of choice and the advantages and disadvantages that this technology offers.

  13. Stable vacuum UV CCD detectors designed for space flight experiments

    NASA Technical Reports Server (NTRS)

    Socker, Dennis G.; Marchywka, Mike; Taylor, G. C.; Levine, P.; Rios, R.; Shallcross, F.; Hughes, G.

    1993-01-01

    Thinned, backside-illuminated, p-channel CCD images are under development which can exploit the surface potential in VUV applications, yielding enhanced quantum efficiency to wavelengths as short as 1100 A. The current goal is production of large-format, 5-micron pixel imagers for spectrographic and imaging VUV spaceflight experiments. Model predictions of the effect of device design on quantum efficiency, well capacity, and crosstalk are presented for such 5-micron-approaching pixel sizes.

  14. An advanced image analysis tool for the quantification and characterization of breast cancer in microscopy images.

    PubMed

    Goudas, Theodosios; Maglogiannis, Ilias

    2015-03-01

    The paper presents an advanced image analysis tool for the accurate and fast characterization and quantification of cancer and apoptotic cells in microscopy images. The proposed tool utilizes adaptive thresholding and a Support Vector Machines classifier. The segmentation results are enhanced through a Majority Voting and a Watershed technique, while an object labeling algorithm has been developed for the fast and accurate validation of the recognized cells. Expert pathologists evaluated the tool and the reported results are satisfying and reproducible. PMID:25681102

  15. Quantitative Computed Tomography and Image Analysis for Advanced Muscle Assessment

    PubMed Central

    Edmunds, Kyle Joseph; Gíslason, Magnus K.; Arnadottir, Iris D.; Marcante, Andrea; Piccione, Francesco; Gargiulo, Paolo

    2016-01-01

    Medical imaging is of particular interest in the field of translational myology, as extant literature describes the utilization of a wide variety of techniques to non-invasively recapitulate and quantity various internal and external tissue morphologies. In the clinical context, medical imaging remains a vital tool for diagnostics and investigative assessment. This review outlines the results from several investigations on the use of computed tomography (CT) and image analysis techniques to assess muscle conditions and degenerative process due to aging or pathological conditions. Herein, we detail the acquisition of spiral CT images and the use of advanced image analysis tools to characterize muscles in 2D and 3D. Results from these studies recapitulate changes in tissue composition within muscles, as visualized by the association of tissue types to specified Hounsfield Unit (HU) values for fat, loose connective tissue or atrophic muscle, and normal muscle, including fascia and tendon. We show how results from these analyses can be presented as both average HU values and compositions with respect to total muscle volumes, demonstrating the reliability of these tools to monitor, assess and characterize muscle degeneration. PMID:27478562

  16. Recent Advances in Molecular Magnetic Resonance Imaging of Liver Fibrosis

    PubMed Central

    Li, Zhiming; Sun, Jihong; Yang, Xiaoming

    2015-01-01

    Liver fibrosis is a life-threatening disease with high morbidity and mortality owing to its diverse causes. Liver biopsy, as the current gold standard for diagnosing and staging liver fibrosis, has a number of limitations, including sample variability, relatively high cost, an invasive nature, and the potential of complications. Most importantly, in clinical practice, patients often reject additional liver biopsies after initiating treatment despite their being necessary for long-term follow-up. To resolve these problems, a number of different noninvasive imaging-based methods have been developed for accurate diagnosis of liver fibrosis. However, these techniques only reflect morphological or perfusion-related alterations in the liver, and thus they are generally only useful for the diagnosis of late-stage liver fibrosis (liver cirrhosis), which is already characterized by “irreversible” anatomic and hemodynamic changes. Thus, it is essential that new approaches are developed for accurately diagnosing early-stage liver fibrosis as at this stage the disease may be “reversed” by active treatment. The development of molecular MR imaging technology has potential in this regard, as it facilitates noninvasive, target-specific imaging of liver fibrosis. We provide an overview of recent advances in molecular MR imaging for the diagnosis and staging of liver fibrosis and we compare novel technologies with conventional MR imaging techniques. PMID:25874221

  17. Imaging of the heart: historical perspective and recent advances.

    PubMed

    Lam, W C; Pennell, D J

    2016-02-01

    Correct diagnosis must be made before appropriate treatment can be given. The aim of cardiac imaging is to establish cardiac diagnosis as accurate as possible and to avert unnecessary invasive procedures. There are many different modalities of cardiac imaging and each of them has advanced tremendously throughout the past decades. Echocardiography, as the first-line modality in most clinical circumstances, has progressed from two-dimensional, single-planed M-mode in the 1960s to three-dimensional speckle tracking echocardiography nowadays. Cardiac computed tomography angiogram (CCTA) has revolutionised the management of coronary artery disease as it allows clinicians to visualise the coronary arteries without performing an invasive angiogram. Because of the high negative predictive value, CCTA plays an important reassuring role in acute chest pain management. The greatest strength of cardiovascular magnetic resonance (CMR) is that it provides information in tissue characterization. It is the modality of choice in assessing myocardial viability and myocardial infiltration such as haemochromatosis or amyloidosis. Each of these modalities has its own strengths and limitations. In fact, they are complementing each other in different clinical settings. Cardiac imaging will continue to advance and, not long from now, we will not need invasive procedures to make an accurate cardiac diagnosis. PMID:26647305

  18. Technology in radiology: advances in diagnostic imaging & therapeutics.

    PubMed

    Stern, S M

    1993-01-01

    Nearly 100 years from its birth, radiology continues to grow as though still in adolescence. Although some radiologic technologies have matured more than others, new applications and techniques appear regularly in the literature. Radiology has evolved from purely diagnostic devices to interventional technologies. New contrast agents in MRI, X ray and ultrasound enable physicians to make diagnoses and plan therapies with greater precision than ever before. Techniques are less and less invasive. Advances in computer technology have given supercomputer-like power to high-end nuclear medicine and MRI systems. Imaging systems in most modalities are now designed with upgrades in mind instead of "planned obsolescence." Companies routinely upgrade software and other facets of their products, sometimes at no additional charge to existing customers. Hospitals, radiology groups and imaging centers will face increasing demands to justify what they do according to patient outcomes and management criteria. Did images make the diagnosis or confirm it? Did the images determine optimal treatment strategies or confirm which strategies might be appropriate? Third-party payers, especially the government, will view radiology in those terms. The diagnostic imaging and therapy systems of today require increasingly sophisticated technical support for maintenance and repair. Hospitals, radiology groups and imaging centers will have to determine the most economic and effective ways to guarantee equipment up-time. Borrowing from the automotive industry, some radiology manufacturers have devised transtelephonic software systems to facilitate remote troubleshooting. To ensure their fiscal viability, hospitals continue to acquire new imaging and therapy technologies for competitive and access-to-services reasons.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:10129808

  19. A CCD search for geosynchronous debris

    NASA Technical Reports Server (NTRS)

    Gehrels, Tom; Vilas, Faith

    1986-01-01

    Using the Spacewatch Camera, a search was conducted for objects in geosynchronous earth orbit. The system is equipped with a CCD camera cooled with dry ice; the image scale is 1.344 arcsec/pixel. The telescope drive was off so that during integrations the stars were trailed while geostationary objects appeared as round images. The technique should detect geostationary objects to a limiting apparent visual magnitude of 19. A sky area of 8.8 square degrees was searched for geostationary objects while geosynchronous debris passing through was 16.4 square degrees. Ten objects were found of which seven are probably geostationary satellites having apparent visual magnitudes brighter than 13.1. Three objects having magnitudes equal to or fainter than 13.7 showed motion in the north-south direction. The absence of fainter stationary objects suggests that a gap in debris size exists between satellites and particles having diameters in the millimeter range.

  20. CCD sensors for spacecraft optical navigation

    NASA Technical Reports Server (NTRS)

    Eisenman, A. R.; Alexander, J. W.; Stanton, R. H.

    1979-01-01

    The optical navigation process uses spaceborne measurements of the apparent direction vector from the spacecraft to a target body, (planet, satellite, star, etc.) to improve estimates of the spacecraft trajectory. Ground-based controllers assimilate the optical measurements, together with spacecraft radio-tracking data and target ephemeris data, to generate a best estimate of the trajectory relative to the target. The present paper deals with a development program supporting the use of (solid state) CCD (Charged Coupled Device) imagers for spacecraft navigation. It is shown that stars can be detected that are two to three magnitudes fainter than with an equivalent vidicon based instrument, that effects of global response nonuniformity and dark current spikes can be essentially eliminated from the data as a result of the reproducibility of both effects, and that charge trailing during readout of star image data can lead to position measurement errors.

  1. Millimeter-Wave Imaging Technology Advancements for Plasma Diagnostics Applications

    NASA Astrophysics Data System (ADS)

    Kong, Xiangyu

    To realize fusion plant, the very first step is to understand the fundamental physics of materials under fusion conditions, i.e. to understand fusion plasmas. Our research group, Plasma Diagnostics Group, focuses on developing advanced tools for physicists to extract as much information as possible from fusion plasmas at millions degrees. The Electron Cyclotron Emission Imaging (ECEI) diagnostics is a very useful tool invented in this group to study fusion plasma electron temperature and it fluctuations. This dissertation presents millimeter wave imaging technology advances recently developed in this group to improve the ECEI system. New technologies made it more powerful to image and visualize magneto-hydrodynamics (MHD) activities and micro-turbulence in fusion plasmas. Topics of particular emphasis start from development of miniaturized elliptical substrate lens array. This novel substrate lens array replaces the previous generation substrate lens, hyper-hemispherical substrate lens, in terms of geometry. From the optical performance perspective, this substitution not only significantly simplifies the optical system with improved optical coupling, but also enhances the RF/LO coupling efficiency. By the benefit of the mini lens focusing properties, a wideband dual-dipole antenna array is carefully designed and developed. The new antenna array is optimized simultaneously for receiving both RF and LO, with sharp radiation patterns, low side-lobe levels, and less crosstalk between adjacent antennas. In addition, a high frequency antenna is also developed, which extends the frequency limit from 145 GHz to 220 GHz. This type of antenna will be used on high field operation tokamaks with toroidal fields in excess of 3 Tesla. Another important technology advance is so-called extended bandwidth double down-conversion electronics. This new electronics extends the instantaneous IF coverage from 2 to 9.2 GHz to 2 to 16.4 GHz. From the plasma point of view, it means that the

  2. Color measurements using a colorimeter and a CCD camera

    SciTech Connect

    Spratlin, T.L.; Simpson, M.L.

    1992-02-01

    Two new techniques are introduced for measuring the color content of printed graphic images with applications to web inspection such as color flaws and measurement of color quality. The techniques involve the development of algorithms for combining the information obtained from commercially available CCD color cameras and colorimeters to produce a colorimeter system with pixel resolution. 9 refs.

  3. The Advanced Gamma-ray Imaging System (AGIS) - Simulation Studies

    SciTech Connect

    Maier, G.; Buckley, J.; Bugaev, V.; Fegan, S.; Vassiliev, V. V.; Funk, S.; Konopelko, A.

    2008-12-24

    The Advanced Gamma-ray Imaging System (AGIS) is a US-led concept for a next-generation instrument in ground-based very-high-energy gamma-ray astronomy. The most important design requirement for AGIS is a sensitivity of about 10 times greater than current observatories like Veritas, H.E.S.S or MAGIC. We present results of simulation studies of various possible designs for AGIS. The primary characteristics of the array performance, collecting area, angular resolution, background rejection, and sensitivity are discussed.

  4. The Advanced Gamma-ray Imaging System (AGIS): Simulation studies

    SciTech Connect

    Maier, G.; Buckley, J.; Bugaev, V.; Fegan, S.; Funk, S.; Konopelko, A.; Vassiliev, V.V.; /UCLA

    2011-06-14

    The Advanced Gamma-ray Imaging System (AGIS) is a next-generation ground-based gamma-ray observatory being planned in the U.S. The anticipated sensitivity of AGIS is about one order of magnitude better than the sensitivity of current observatories, allowing it to measure gamma-ray emission from a large number of Galactic and extra-galactic sources. We present here results of simulation studies of various possible designs for AGIS. The primary characteristics of the array performance - collecting area, angular resolution, background rejection, and sensitivity - are discussed.

  5. A large area cooled-CCD detector for electron microscopy

    NASA Astrophysics Data System (ADS)

    Faruqi, A. R.; Andrews, H. N.; Raeburn, C.

    1994-09-01

    Large area cooled-CCDs are an excellent medium for (indirectly) recording electron images and electron diffraction patterns in real time and for use in electron tomography; real-time imaging is extremely useful in making rapid adjustments in the electron microscope. CCDs provide high sensitivity (useful for minimising dosage to radiation-sensitive biological specimen), good resolution, stable performance, excellent dynamic range and linearity and a reasonably fast readout. We have built an electron imaging device based on the EEV 1152 by 814 pixel CCD which is controlled from a unix based SUN Sparestation operating under X-Windows. The incident 100 kV electrons are converted to visible light in a 0.5 mm thick YAG single crystal which is imaged through a lens on to the CCD. The CCD electronics is designed to be as flexible as possible and allows a wide variation in the readout speed to cater for the relatively fast application where readout noise is less critical and low readout noise applications where the extra few seconds of readout time are not significant. The CCD electronics is built in VME format which is controlled through a S-bus to VME driver. With two parallel channels of readout the whole image can be read out in ˜ 1 s (using the faster readout speed) with 16 bit precision and the image is displayed under X-Windows in a few seconds. The present readout works at 500 kHz and has a noise of ˜ 30 e rms per pixel. With a Peltier cooling device we can operate the CCD at ˜ -40°C which reduces the dark current adequately to allow exposures of up to several minutes. Several examples of patterns collected with the system on a Philips CM12 microscope will be presented.

  6. Advances in imaging ultrastructure yield new insights into presynaptic biology

    PubMed Central

    Bruckner, Joseph J.; Zhan, Hong; O’Connor-Giles, Kate M.

    2015-01-01

    Synapses are the fundamental functional units of neural circuits, and their dysregulation has been implicated in diverse neurological disorders. At presynaptic terminals, neurotransmitter-filled synaptic vesicles are released in response to calcium influx through voltage-gated calcium channels activated by the arrival of an action potential. Decades of electrophysiological, biochemical, and genetic studies have contributed to a growing understanding of presynaptic biology. Imaging studies are yielding new insights into how synapses are organized to carry out their critical functions. The development of techniques for rapid immobilization and preservation of neuronal tissues for electron microscopy (EM) has led to a new renaissance in ultrastructural imaging that is rapidly advancing our understanding of synapse structure and function. PMID:26052269

  7. Glaucoma Diagnosis and Monitoring Using Advanced Imaging Technologies

    PubMed Central

    Sehi, Mitra; Iverson, Shawn M

    2014-01-01

    Advanced ocular imaging technologies facilitate objective and reproducible quantification of change in glaucoma but at the same time, impose new challenges on scientists and clinicians for separating true structural change from imaging noise. This review examines time-domain and spectral-domain optical coherence tomography, confocal scanning laser ophthalmoscopy and scanning laser polarimetry technologies and discusses the diagnostic accuracy and the ability of each technique for evaluation of glaucomatous progression. A broad review of the current literature reveals that objective assessment of retinal nerve fiber layer, ganglion cell complex and optic nerve head topography may improve glaucoma monitoring when used as a complementary tool in conjunction with the clinical judgment of an expert. PMID:24470807

  8. Recent Advances in the Imaging of Frontotemporal Dementia

    PubMed Central

    Whitwell, Jennifer L.; Josephs, Keith A.

    2012-01-01

    Neuroimaging has played an important role in the characterization of the frontotemporal dementia (FTD) syndromes, demonstrating neurodegenerative signatures that can aid in the differentiation of FTD from other neurodegenerative disorders. Recent advances have been driven largely by the refinement of the clinical syndromes that underlie FTD, and by the discovery of new genetic and pathological features associated with FTD. Many new imaging techniques and modalities are also now available that allow the assessment of other aspects of brain structure and function, such as diffusion tensor imaging and resting state functional MRI. Studies have utilized these recent techniques, as well as traditional volumetric MRI, to provide further insight into disease progression across the many clinical, genetic and pathological variants of FTD. Importantly, neuroimaging signatures have been identified that will improve the clinician’s ability to predict underlying genetic and pathological features, and hence ultimately improve patient diagnosis. PMID:23015371

  9. Advanced DTM Generation from Very High Resolution Satellite Stereo Images

    NASA Astrophysics Data System (ADS)

    Perko, R.; Raggam, H.; Gutjahr, K. H.; Schardt, M.

    2015-03-01

    This work proposes a simple filtering approach that can be applied to digital surface models in order to extract digital terrain models. The method focusses on robustness and computational efficiency and is in particular tailored to filter DSMs that are extracted from satellite stereo images. It represents an evolution of an existing DTM generation method and includes distinct advancement through the integration of multi-directional processing as well as slope dependent filtering, thus denoted "MSD filtering". The DTM generation workflow is fully automatic and requires no user interaction. Exemplary results are presented for a DSM generated from a Pléiades tri-stereo image data set. Qualitative and quantitative evaluations with respect to highly accurate reference LiDAR data confirm the effectiveness of the proposed algorithm.

  10. Recent advances in live cell imaging of hepatoma cells

    PubMed Central

    2014-01-01

    Live cell imaging enables the study of dynamic processes of living cells in real time by use of suitable reporter proteins and the staining of specific cellular structures and/or organelles. With the availability of advanced optical devices and improved cell culture protocols it has become a rapidly growing research methodology. The success of this technique relies mainly on the selection of suitable reporter proteins, construction of recombinant plasmids possessing cell type specific promoters as well as reliable methods of gene transfer. This review aims to provide an overview of the recent developments in the field of marker proteins (bioluminescence and fluorescent) and methodologies (fluorescent resonance energy transfer, fluorescent recovery after photobleaching and proximity ligation assay) employed as to achieve an improved imaging of biological processes in hepatoma cells. Moreover, different expression systems of marker proteins and the modes of gene transfer are discussed with emphasis on the study of lipid droplet formation in hepatocytes as an example. PMID:25005127

  11. Advances on image interpolation based on ant colony algorithm.

    PubMed

    Rukundo, Olivier; Cao, Hanqiang

    2016-01-01

    This paper presents an advance on image interpolation based on ant colony algorithm (AACA) for high resolution image scaling. The difference between the proposed algorithm and the previously proposed optimization of bilinear interpolation based on ant colony algorithm (OBACA) is that AACA uses global weighting, whereas OBACA uses local weighting scheme. The strength of the proposed global weighting of AACA algorithm depends on employing solely the pheromone matrix information present on any group of four adjacent pixels to decide which case deserves a maximum global weight value or not. Experimental results are further provided to show the higher performance of the proposed AACA algorithm with reference to the algorithms mentioned in this paper. PMID:27047729

  12. Advances and challenges in deformable image registration: From image fusion to complex motion modelling.

    PubMed

    Schnabel, Julia A; Heinrich, Mattias P; Papież, Bartłomiej W; Brady, Sir J Michael

    2016-10-01

    Over the past 20 years, the field of medical image registration has significantly advanced from multi-modal image fusion to highly non-linear, deformable image registration for a wide range of medical applications and imaging modalities, involving the compensation and analysis of physiological organ motion or of tissue changes due to growth or disease patterns. While the original focus of image registration has predominantly been on correcting for rigid-body motion of brain image volumes acquired at different scanning sessions, often with different modalities, the advent of dedicated longitudinal and cross-sectional brain studies soon necessitated the development of more sophisticated methods that are able to detect and measure local structural or functional changes, or group differences. Moving outside of the brain, cine imaging and dynamic imaging required the development of deformable image registration to directly measure or compensate for local tissue motion. Since then, deformable image registration has become a general enabling technology. In this work we will present our own contributions to the state-of-the-art in deformable multi-modal fusion and complex motion modelling, and then discuss remaining challenges and provide future perspectives to the field. PMID:27364430

  13. Time series photometry of faint cataclysmic variables with a CCD

    NASA Astrophysics Data System (ADS)

    Abbott, Timothy Mark Cameron

    1992-08-01

    I describe a new hardware and software environment for the practice of time-series stellar photometry with the CCD systems available at McDonald Observatory. This instrument runs suitable CCD's in frame transfer mode and permits windowing on the CCD image to maximize the duty cycle of the photometer. Light curves may be extracted and analyzed in real time at the telescope and image data are stored for later, more thorough analysis. I describe a star tracking algorithm, which is optimized for a timeseries of images of the same stellar field. I explore the extraction of stellar brightness measures from these images using circular software apertures and develop a complete description of the noise properties of this technique. I show that scintillation and pixelization noise have a significant effect on high quality observations. I demonstrate that optimal sampling and profile fitting techniques are unnecessarily complex or detrimental methods of obtaining stellar brightness measures under conditions commonly encountered in timeseries CCD photometry. I compare CCD's and photomultiplier tubes as detectors for timeseries photometry using light curves of a variety of stars obtained simultaneously with both detectors and under equivalent conditions. A CCD can produce useful data under conditions when a photomultiplier tube cannot, and a CCD will often produce more reliable results even under photometric conditions. I prevent studies of the cataclysmic variables (CV's) AL Com, CP Eri, V Per, and DO Leo made using the time series CCD photometer. AL Com is a very faint CV at high Galactic latitude and a bona fide Population II CV. Some of the properties of AL Com are similar to the dwarf nova WZ Sge and others are similar to the intermediate polar EX Hya, but overall AL Com is unlike any other well-studied cataclysmic variable. CP Eri is shown to be the fifth known interacting binary white dwarf. V Per was the first CV found to have an orbital period near the middle of the

  14. Advanced 3D imaging lidar concepts for long range sensing

    NASA Astrophysics Data System (ADS)

    Gordon, K. J.; Hiskett, P. A.; Lamb, R. A.

    2014-06-01

    Recent developments in 3D imaging lidar are presented. Long range 3D imaging using photon counting is now a possibility, offering a low-cost approach to integrated remote sensing with step changing advantages in size, weight and power compared to conventional analogue active imaging technology. We report results using a Geiger-mode array for time-of-flight, single photon counting lidar for depth profiling and determination of the shape and size of tree canopies and distributed surface reflections at a range of 9km, with 4μJ pulses with a frame rate of 100kHz using a low-cost fibre laser operating at a wavelength of λ=1.5 μm. The range resolution is less than 4cm providing very high depth resolution for target identification. This specification opens up several additional functionalities for advanced lidar, for example: absolute rangefinding and depth profiling for long range identification, optical communications, turbulence sensing and time-of-flight spectroscopy. Future concepts for 3D time-of-flight polarimetric and multispectral imaging lidar, with optical communications in a single integrated system are also proposed.

  15. Diagnosis by Endoscopy and Advanced Imaging of Barrett's Neoplasia.

    PubMed

    Swager, Anne-Fré; Curvers, Wouter L; Bergman, Jacques J

    2016-01-01

    Evaluation of patients with Barrett's esophagus (BE) using dye-based chromoendoscopy, optical chromoendoscopy, autofluorescence imaging, or confocal laser endomicroscopy does not significantly increase the number of patients with a diagnosis of early neoplasia compared with high-definition white light endoscopy (HD-WLE) with random biopsy analysis. These newer imaging techniques are not more effective in standard surveillance of patients with BE because the prevalence of early neoplasia is low and HD-WLE with random biopsy analysis detects most cases of neoplasia. The evaluation and treatment of patients with BE and early stage neoplasia should be centralized in tertiary referral centers, where procedures are performed under optimal conditions, by expert endoscopists. Lesions that require resection are almost always detected by HD-WLE, although advanced imaging techniques can detect additional flat lesions. However, these are of limited clinical significance because they are effectively eradicated by ablation therapy. No endoscopic imaging technique can reliably assess submucosal or lymphangio invasion. Endoscopic resection of early stage neoplasia in patients with BE is important for staging and management. Optical chromoendoscopy can also be used to evaluate lesions before endoscopic resection and in follow-up after successful ablation therapy. PMID:27573768

  16. Recent Advances in Techniques for Hyperspectral Image Processing

    NASA Technical Reports Server (NTRS)

    Plaza, Antonio; Benediktsson, Jon Atli; Boardman, Joseph W.; Brazile, Jason; Bruzzone, Lorenzo; Camps-Valls, Gustavo; Chanussot, Jocelyn; Fauvel, Mathieu; Gamba, Paolo; Gualtieri, Anthony; Marconcini, Mattia; Tilton, James C.; Trianni, Giovanna

    2009-01-01

    Imaging spectroscopy, also known as hyperspectral imaging, has been transformed in less than 30 years from being a sparse research tool into a commodity product available to a broad user community. Currently, there is a need for standardized data processing techniques able to take into account the special properties of hyperspectral data. In this paper, we provide a seminal view on recent advances in techniques for hyperspectral image processing. Our main focus is on the design of techniques able to deal with the highdimensional nature of the data, and to integrate the spatial and spectral information. Performance of the discussed techniques is evaluated in different analysis scenarios. To satisfy time-critical constraints in specific applications, we also develop efficient parallel implementations of some of the discussed algorithms. Combined, these parts provide an excellent snapshot of the state-of-the-art in those areas, and offer a thoughtful perspective on future potentials and emerging challenges in the design of robust hyperspectral imaging algorithms

  17. Microwave Imaging for Breast Cancer Detection: Advances in Three–Dimensional Image Reconstruction

    PubMed Central

    Golnabi, Amir H.; Meaney, Paul M.; Epstein, Neil R.; Paulsen, Keith D.

    2013-01-01

    Microwave imaging is based on the electrical property (permittivity and conductivity) differences in materials. Microwave imaging for biomedical applications is particularly interesting, mainly due to the fact that available range of dielectric properties for different tissues can provide important functional information about their health. Under the assumption that a 3D scattering problem can be reasonably represented as a simplified 2D model, one can take advantage of the simplicity and lower computational cost of 2D models to characterize such 3D phenomenon. Nonetheless, by eliminating excessive model simplifications, 3D microwave imaging provides potentially more valuable information over 2Dtechniques, and as a result, more accurate dielectric property maps may be obtained. In this paper, we present some advances we have made in three–dimensional image reconstruction, and show the results from a 3D breast phantom experiment using our clinical microwave imaging system at Dartmouth Hitchcock Medical Center (DHMC), NH. PMID:22255641

  18. Solid state television camera (CCD-buried channel)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The development of an all solid state television camera, which uses a buried channel charge coupled device (CCD) as the image sensor, was undertaken. A 380 x 488 element CCD array is utilized to ensure compatibility with 525 line transmission and display monitor equipment. Specific camera design approaches selected for study and analysis included (a) optional clocking modes for either fast (1/60 second) or normal (1/30 second) frame readout, (b) techniques for the elimination or suppression of CCD blemish effects, and (c) automatic light control and video gain control (i.e., ALC and AGC) techniques to eliminate or minimize sensor overload due to bright objects in the scene. Preferred approaches were determined and integrated into a deliverable solid state TV camera which addressed the program requirements for a prototype qualifiable to space environment conditions.

  19. Extreme ultraviolet response of a Tektronix 1024 x 1024 CCD

    NASA Astrophysics Data System (ADS)

    Moses, Daniel J.; Hochedez, Jean-Francois E.; Howard, Russell A.; Au, Benjamin D.; Wang, Dennis; Blouke, Morley

    1992-08-01

    The goal of the detector development program for the Solar and Heliospheric Spacecraft (SOHO) EUV Imaging Telescope (EIT) is an Extreme UltraViolet (EUV) CCD (Charge Coupled Device) camera. The Naval Research Lab (NRL) SOHO COD Group has developed a design for the EIT camera and is screening CCDs for flight application. Tektronix Inc. have fabricated 1024x1024 CCDs for the EIT program. As a part of the CCD screening effort the quantum efficiency (QE) of a prototype CCD has been measured in the NRL EUV laboratory over the wavelength range of 256 to 735 Angstroms. A simplified model has been applied to these QE measurements to illustrate the relevant physical processes that determine the performance of the detector.

  20. Advances in infrared and imaging fibres for astronomical instrumentation

    NASA Astrophysics Data System (ADS)

    Haynes, Roger; McNamara, Pam; Marcel, Jackie; Jovanovic, Nemanja

    2006-06-01

    Optical fibres have already played a huge part in ground based astronomical instrumentation, however, with the revolution in photonics currently taking place new fibre technologies and integrated optical devices are likely to have a profound impact on the way we manipulate light in the future. The Anglo Australian Observatory, along with partners at the Optical Fibre Technology Centre of the University of Sydney, is investigating some of the developing technologies as part of our Astrophotonics programme2. In this paper we discuss the advances that have been made with infrared transmitting fibre, both conventional and microstructured, in particular those based on fluoride glasses. Fluoride glasses have a particularly wide transparent region from the UV through to around 7μm, whereas silica fibres, commonly used in astronomy, only transmit out to about 2μm. We discuss the impact of advances in fibre manufacture that have greatly improved the optical, chemical resistance and physical properties of the fluoride fibres. We also present some encouraging initial test results for a modern imaging fibre bundle and imaging fibre taper.

  1. Precise Determination of Brillouin Scattering Spectrum Using a Virtually Imaged Phase Array (VIPA) Spectrometer and Charge-Coupled Device (CCD) Camera.

    PubMed

    Meng, Zhaokai; Yakovlev, Vladislav V

    2016-08-01

    Brillouin spectroscopy is an emerging tool for microscopic optical imaging as it allows noninvasive assessment of viscoelastic properties of materials. The use of atomic-molecular absorption cells as ultra-narrow notch filters allows acquisition of Brillouin spectra from turbid samples despite their strong elastic scattering. However, such systems alter the shapes of the Brillouin lines, making the precise determination of the Brillouin shift difficult. In this report, we propose a simple method for analyzing the Brillouin spectrum using a customized least-square fitting algorithm. The absorption spectrum induced by the atomic-molecular cell was taken into consideration. The capability of the method is confirmed by processing experimental spectroscopic data from the pure water at different temperatures. The accuracy of the measurements of ±1 MHz spectral line shift is experimentally demonstrated. PMID:27296309

  2. Determination of visible coordinates of the low-orbit space objects and their photometry by the CCD camera with the analogue output. Initial image processing

    NASA Astrophysics Data System (ADS)

    Shakun, L. S.; Koshkin, N. I.

    2014-06-01

    The number of artificial space objects in the low Earth orbit has been continuously increasing. That raises the requirements for the accuracy of measurement of their coordinates and for the precision of the prediction of their motion. The accuracy of the prediction can be improved if the actual current orientation of the non-spherical satellite is taken into account. In so doing, it becomes possible to directly determine the atmospheric density along the orbit. The problem solution is to regularly conduct the photometric surveillances of a large number of satellites and monitor the parameters of their rotation around the centre of mass. To do that, it is necessary to get and promptly process large video arrays, containing pictures of a satellite against the background stars. In the present paper, the method for the simultaneous measurement of coordinates and brightness of the low Earth orbit space objects against the background stars when they are tracked by telescope KT-50 with the mirror diameter of 50 cm and with video camera WAT-209H2 is considered. The problem of determination of the moments of exposures of images is examined in detail. The estimation of the accuracy of measuring both the apparent coordinates of stars and their photometry is given on the example of observation of the open star cluster. In the presented observations, the standard deviation of one position measured is 1σ, the accuracy of determination of the moment of exposure of images is better than 0.0001 s. The estimate of the standard deviation of one measurement of brightness is 0.1m. Some examples of the results of surveillances of satellites are also presented in the paper.

  3. The Effectiveness of Advance Organizers on the Signification of Poetic Images

    ERIC Educational Resources Information Center

    Bayat, Nihat

    2007-01-01

    Advance organizers activate the most suitable schema to learn new material. Poetic images are signified in schemata and the elements which are not expressed may be called by advance organizers. The purpose of this investigation is to discern the effectiveness of advance organizers on the signification of poetic images. Pretest-posttest…

  4. Advances in ultrasound imaging for congenital malformations during early gestation

    PubMed Central

    Rayburn, William F.; Jolley, Jennifer A.; Simpson, Lynn L.

    2015-01-01

    With refinement in ultrasound technology, detection of fetal structural abnormalities has improved and there have been detailed reports of the natural history and expected outcomes for many anomalies. The ability to either reassure a high-risk woman with normal intrauterine images or offer comprehensive counseling and offer options in cases of strongly suspected lethal or major malformations has shifted prenatal diagnoses to the earliest possible gestational age. When indicated, scans in early gestation are valuable in accurate gestational dating. Stricter sonographic criteria for early nonviability guard against unnecessary intervention. Most birth defects are without known risk factors, and detection of certain malformations is possible in the late first trimester. The best time for a standard complete fetal and placental scan is 18–20 weeks. In addition, certain soft anatomic markers provide clues to chromosomal aneuploidy risk. Maternal obesity and multifetal pregnancies are now more common and further limit early gestation visibility. Other advanced imaging techniques during early gestation in select cases of suspected malformations include fetal echocardiography and magnetic resonance imaging. PMID:25820190

  5. Advanced Imaging in Femoroacetabular Impingement: Current State and Future Prospects

    PubMed Central

    Bittersohl, Bernd; Hosalkar, Harish S.; Hesper, Tobias; Tiderius, Carl Johan; Zilkens, Christoph; Krauspe, Rüdiger

    2015-01-01

    Symptomatic femoroacetabular impingement (FAI) is now a known precursor of early osteoarthritis (OA) of the hip. In terms of clinical intervention, the decision between joint preservation and joint replacement hinges on the severity of articular cartilage degeneration. The exact threshold during the course of disease progression when the cartilage damage is irreparable remains elusive. The intention behind radiographic imaging is to accurately identify the morphology of osseous structural abnormalities and to accurately characterize the chondrolabral damage as much as possible. However, both plain radiographs and computed tomography (CT) are insensitive for articular cartilage anatomy and pathology. Advanced magnetic resonance imaging (MRI) techniques include magnetic resonance arthrography and biochemically sensitive techniques of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T1rho (T1ρ), T2/T2* mapping, and several others. The diagnostic performance of these techniques to evaluate cartilage degeneration could improve the ability to predict an individual patient-specific outcome with non-surgical and surgical care. This review discusses the facts and current applications of biochemical MRI for hip joint cartilage assessment covering the roles of dGEMRIC, T2/T2*, and T1ρ mapping. The basics of each technique and their specific role in FAI assessment are outlined. Current limitations and potential pitfalls as well as future directions of biochemical imaging are also outlined. PMID:26258129

  6. Advanced Imaging in Femoroacetabular Impingement: Current State and Future Prospects.

    PubMed

    Bittersohl, Bernd; Hosalkar, Harish S; Hesper, Tobias; Tiderius, Carl Johan; Zilkens, Christoph; Krauspe, Rüdiger

    2015-01-01

    Symptomatic femoroacetabular impingement (FAI) is now a known precursor of early osteoarthritis (OA) of the hip. In terms of clinical intervention, the decision between joint preservation and joint replacement hinges on the severity of articular cartilage degeneration. The exact threshold during the course of disease progression when the cartilage damage is irreparable remains elusive. The intention behind radiographic imaging is to accurately identify the morphology of osseous structural abnormalities and to accurately characterize the chondrolabral damage as much as possible. However, both plain radiographs and computed tomography (CT) are insensitive for articular cartilage anatomy and pathology. Advanced magnetic resonance imaging (MRI) techniques include magnetic resonance arthrography and biochemically sensitive techniques of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T1rho (T1ρ), T2/T2* mapping, and several others. The diagnostic performance of these techniques to evaluate cartilage degeneration could improve the ability to predict an individual patient-specific outcome with non-surgical and surgical care. This review discusses the facts and current applications of biochemical MRI for hip joint cartilage assessment covering the roles of dGEMRIC, T2/T2*, and T1ρ mapping. The basics of each technique and their specific role in FAI assessment are outlined. Current limitations and potential pitfalls as well as future directions of biochemical imaging are also outlined. PMID:26258129

  7. AXIOM: advanced X-ray imaging of the magnetosphere

    NASA Astrophysics Data System (ADS)

    Branduardi-Raymont, Graziella; Sembay, Steve F.; Eastwood, Jonathan P.; Sibeck, David G.; Abbey, Tony A.; Brown, Patrick; Carter, Jenny A.; Carr, Chris M.; Forsyth, Colin; Kataria, Dhiren; Kemble, Steve; Milan, Steve E.; Owen, Chris J.; Peacocke, Lisa; Read, Andy M.; Coates, Andrew J.; Collier, Michael R.; Cowley, Stan W. H.; Fazakerley, Andrew N.; Fraser, George W.; Jones, Geraint H.; Lallement, Rosine; Lester, Mark; Porter, F. Scott; Yeoman, Tim K.

    2012-04-01

    Planetary plasma and magnetic field environments can be studied in two complementary ways—by in situ measurements, or by remote sensing. While the former provide precise information about plasma behaviour, instabilities and dynamics on local scales, the latter offers the global view necessary to understand the overall interaction of the magnetospheric plasma with the solar wind. Some parts of the Earth's magnetosphere have been remotely sensed, but the majority remains unexplored by this type of measurements. Here we propose a novel and more elegant approach employing remote X-ray imaging techniques, which are now possible thanks to the relatively recent discovery of solar wind charge exchange X-ray emissions in the vicinity of the Earth's magnetosphere. In this article we describe how an appropriately designed and located X-ray telescope, supported by simultaneous in situ measurements of the solar wind, can be used to image the dayside magnetosphere, magnetosheath and bow shock, with a temporal and spatial resolution sufficient to address several key outstanding questions concerning how the solar wind interacts with the Earth's magnetosphere on a global level. Global images of the dayside magnetospheric boundaries require vantage points well outside the magnetosphere. Our studies have led us to propose `AXIOM: Advanced X-ray Imaging of the Magnetosphere', a concept mission using a Vega launcher with a LISA Pathfinder-type Propulsion Module to place the spacecraft in a Lissajous orbit around the Earth-Moon L1 point. The model payload consists of an X-ray Wide Field Imager, capable of both imaging and spectroscopy, and an in situ plasma and magnetic field measurement package. This package comprises a Proton-Alpha Sensor, designed to measure the bulk properties of the solar wind, an Ion Composition Analyser, to characterise the minor ion populations in the solar wind that cause charge exchange emission, and a Magnetometer, designed to measure the strength and

  8. AXIOM: Advanced X-ray Imaging of the Magnetosphere

    NASA Technical Reports Server (NTRS)

    Branduardi-Raymont, G.; Sembay, S. F.; Eastwood, J. P.; Sibeck, D. G.; Abbey, A.; Brown, P.; Carter, J. A.; Carr, C. M.; Forsyth, C.; Kataria, D.; Kemble, S.; Milan, S. E.; Owen, C. J.; Peacocke, L.; Read, A. M.; Coates, A. J.; Collier, M. R.; Cowley, S. W. H.; Fazakerley, A. N.; Fraser, G. W.; Jones, G. H.; Lallement, R.; Lester, M.; Porter, F. S.; Yeoman, T. K.

    2012-01-01

    Planetary plasma and magnetic field environments can be studied in two complementary ways - by in situ measurements, or by remote sensing. While the former provide precise information about plasma behaviour, instabilities and dynamics on local scales, the latter offers the global view necessary to understand the overall interaction of the magnetospheric plasma with the solar wind. Some parts of the Earth's magnetosphere have been remotely sensed, but the majority remains unexplored by this type of measurements. Here we propose a novel and more elegant approach employing remote X-ray imaging techniques. which are now possible thanks to the relatively recent discovery of solar wind charge exchange X-ray emissions in the vicinity of the Earth's magnetosphere. In this article we describe how an appropriately designed and located. X-ray telescope, supported by simultaneous in situ measurements of the solar wind, can be used to image the dayside magnetosphere, magnetosheath and bow shock. with a temporal and spatial resolution sufficient to address several key outstanding questions concerning how the solar wind interacts with the Earth's magnetosphere on a global level. Global images of the dayside magnetospheric boundaries require vantage points well outside the magnetosphere. Our studies have led us to propose 'AXIOM: Advanced X-ray Imaging Of the Magnetosphere', a concept mission using a Vega launcher with a LISA Pathfinder-type Propulsion Module to place the spacecraft in a Lissajous orbit around the Earth - Moon Ll point. The model payload consists of an X-ray Wide Field Imager, capable of both imaging and spectroscopy, and an in situ plasma and magnetic field measurement package. This package comprises a Proton-Alpha Sensor, designed to measure the bulk properties of the solar wind, an Ion Composition Analyser, to characterize the minor ion populations in the solar wind that cause charge exchange emission, and a Magnetometer, designed to measure the strength and

  9. AXIOM: Advanced X-Ray Imaging of the Magnetosphere

    NASA Technical Reports Server (NTRS)

    Branduardi-Raymont, G.; Sembay, S. F.; Eastwood, J. P.; Sibeck, D. G.; Abbey, A.; Brown, P.; Carter, J. A.; Carr, C. M.; Forsyth, C.; Kataria, D.; Kemble, S.; Milan, S. E.; Owen, C. J.; Peacocke, L.; Read, A. M.; Coates, A. J.; Collier, M. R.; Cowley, S. W. H.; Fazakerley, A. N.; Fraser, G. W.; Jones, G. H.; Lallement, R.; Lester, M.; Porter, F. S.; Yeoman, T. K.

    2011-01-01

    Planetary plasma and magnetic field environments can be studied in two complementary ways by in situ measurements, or by remote sensing. While the former provide precise information about plasma behaviour, instabilities and dynamics on local scales, the latter offers the global view necessary to understand the overall interaction of the magnetospheric plasma with the solar wind. Some parts of the Earth's magnetosphere have been remotely sensed, but the majority remains unexplored by this type of measurements. Here we propose a novel and more elegant approach employing remote X-ray imaging techniques, which are now possible thanks to the relatively recent discovery of solar wind charge exchange X-ray emissions in the vicinity of the Earth's magnetosphere. In this article we describe how an appropriately designed and located X-ray telescope, supported by simultaneous in situ measurements of the solar wind, can be used to image the dayside magnetosphere, magnetosheath and bow shock, with a temporal and spatial resolution sufficient to address several key outstanding questions concerning how the solar wind interacts with the Earth's magnetosphere on a global level. Global images of the dayside magnetospheric boundaries require vantage points well outside the magnetosphere. Our studies have led us to propose AXIOM: Advanced X-ray Imaging Of the Magnetosphere, a concept mission using a Vega launcher with a LISA Pathfinder-type Propulsion Module to place the spacecraft in a Lissajous orbit around the Earth Moon L1 point. The model payload consists of an X-ray Wide Field Imager, capable of both imaging and spectroscopy, and an in situ plasma and magnetic field measurement package. This package comprises a Proton-Alpha Sensor, designed to measure the bulk properties of the solar wind, an Ion Composition Analyser, to characterize the minor ion populations in the solar wind that cause charge exchange emission, and a Magnetometer, designed to measure the strength and direction

  10. Resolved CCD Photometry of Pluto and Charon

    SciTech Connect

    Jones, J.H.; Waddell, P.; Christian, C.A.

    1988-04-01

    Highly resolved CCD images of Pluto and Charon near maximum separation are measured with point spread function fitting techniques to determine independent magnitudes and an accurate separation for Pluto and Charon. A measured separation of 0.923 + or - 0.005 arcsec at a position angle of 173.3 + or - 0.3 deg on June 18, 1987 UT produced a value of 19558.0 + or - 153.0 km for the radius of Charon's orbit. An apparent B magnitude of 14.877 + or - 0.009 and (B-I) color of 1.770 + or - 0.015 are determined for Pluto, while Charon is fainter with B = 18.826 + or - 0.011 and slightly bluer with (B-I) = 1.632 + or - 0.018. 18 references.

  11. CCD observations of old nova fields

    SciTech Connect

    Downes, R.A.; Szkody, P.; Washington Uni., Seattle )

    1989-06-01

    The discovery of CK Vulpeculae (Nova 1670) has prompted a major review of ideas concerning the long-term development of novae. Unfortunately, there are very few recovered novae old enough to provide confirmation (or rejection) of the new hibernation scenario. CCD images of seven old nova fields, and R band photometry for four fields, have been obtained in an attempt to recover these objects in quiescence. A strong candidate for U Leonis, and a possible counterpart for T Bootis, are found. For three other fields, weak candidates have been found. Finding charts and colors are presented for the seven fields observed. The R light curves of U Leo, indicating an orbital period of 192.5 or 385.0 min, are shown. 14 refs.

  12. CCD observations of old nova fields

    NASA Technical Reports Server (NTRS)

    Downes, Ronald A.; Szkody, Paula

    1989-01-01

    The discovery of CK Vulpeculae (Nova 1670) has prompted a major review of ideas concerning the long-term development of novae. Unfortunately, there are very few recovered novae old enough to provide confirmation (or rejection) of the new 'hibernation' scenario. CCD images of seven old nova fields, and R band photometry for four fields, have been obtained in an attempt to recover these objects in quiescence. A strong candidate for U Leonis, and a possible counterpart for T Bootis, are found. For three other fields, weak candidates have been found. Finding charts and colors are presented for the seven fields observed. The R light curves of U Leo, indicating an orbital period of 192.5 or 385.0 min, are shown.

  13. VIIRS Nighttime Lights: Advances in Satellite Low-Light Imaging

    NASA Astrophysics Data System (ADS)

    Hsu, F.; Baugh, K.; Elvidge, C.; Zhizhin, M. N.

    2013-12-01

    The Soumi National Polar-orbiting Partnership (SNPP) Visible Infrared Imaging Radiometer Suite (VIIRS) Day-Night Band (DNB) represents a major advance in low-light imaging over previous data sources. Building on 18 years of experience compositing nighttime data from the Defense Meteorological Satellite Program (DMSP) Operational Linescan System (OLS), NOAA's NGDC Earth Observation Group created the first global VIIRS nighttime lights composite product by adapting their algorithms to process these new data. Compositing nighttime data involves combining only high quality data components over a period of time to improve sensitivity and coverage. Flag image were compiled to describe image quality. The initial flag categories included: daytime, twilight, stray light, non-zero lunar illuminance, noisy edge of scan data, clouds, and no data. High quality data included in the nighttime lights composite is defined as not having any of these attributes present. After the initial adaptation of heritage OLS algorithms, the authors sought to improve the sharpness of lights in the composite by adding additional flag categories. These include a refined VIIRS cloud mask, a mask based on cloud optical thickness, and a ranking of sharpness of light.. The VIIRS cloud mask, which is a JPSS retained intermediate product cloud mask (IICMO) is refined to reject the misclassification of hot sources like gas flares as cloud. Another JPSS retained intermediate product, cloud optical thickness, also provides valuable information about the clarity of atmosphere. The authors also implemented a sharp light detector to further characterize the quality of light for each pixel. Results of compositing multiple months in 2013 using these new flag categories are presented to demonstrate the improvements in nighttime lights composite quality.

  14. Data acquisition system based on the Nios II for a CCD camera

    NASA Astrophysics Data System (ADS)

    Li, Binhua; Hu, Keliang; Wang, Chunrong; Liu, Yangbing; He, Chun

    2006-06-01

    The FPGA with Avalon Bus architecture and Nios soft-core processor developed by Altera Corporation is an advanced embedded solution for control and interface systems. A CCD data acquisition system with an Ethernet terminal port based on the TCP/IP protocol is implemented in NAOC, which is composed of a piece of interface board with an Altera's FPGA, 32MB SDRAM and some other accessory devices integrated on it, and two packages of control software used in the Nios II embedded processor and the remote host PC respectively. The system is used to replace a 7200 series image acquisition card which is inserted in a control and data acquisition PC, and to download commands to an existing CCD camera and collect image data from the camera to the PC. The embedded chip in the system is a Cyclone FPGA with a configurable Nios II soft-core processor. Hardware structure of the system, configuration for the embedded soft-core processor, and peripherals of the processor in the PFGA are described. The C program run in the Nios II embedded system is built in the Nios II IDE kits and the C++ program used in the PC is developed in the Microsoft's Visual C++ environment. Some key techniques in design and implementation of the C and VC++ programs are presented, including the downloading of the camera commands, initialization of the camera, DMA control, TCP/IP communication and UDP data uploading.

  15. Charge transfer efficiency in proton damaged CCD`s

    SciTech Connect

    Hardy, T. |; Murowinski, R.; Deen, M.J.

    1998-04-01

    The authors have performed detailed measurements of the charge transfer efficiency (CTE) in a thinned, backside-illuminated imaging charge-coupled device (CCD). The device had been damaged in three separate sections by proton radiation typical of that which a CCD would receive in space-borne experiments, nuclear imaging, or particle detection. They examined CTE as a function of signal level, temperature, and radiation dose. The dominant factor affecting the CTE in radiation-damaged CCD`s is seen to be trapping by bulk states. They present a simple physical model for trapping as a function of transfer rate, trap concentration, and temperature. They have made calculations using this model and arrived at predictions which closely match the measured results. The CTE was also observed to have a nonlinear dependence on signal level. Using two-dimensional device simulations to examine the distribution of the charge packets in the CCD channel over a range of signal levels, they were able to explain the observed variation.

  16. The 2-d CCD Data Reduction Cookbook

    NASA Astrophysics Data System (ADS)

    Davenhall, A. C.; Privett, G. J.; Taylor, M. B.

    This cookbook presents simple recipes and scripts for reducing direct images acquired with optical CCD detectors. Using these recipes and scripts you can correct un-processed images obtained from CCDs for various instrumental effects to retrieve an accurate picture of the field of sky observed. The recipes and scripts use standard software available at all Starlink sites. The topics covered include: creating and applying bias and flat-field corrections, registering frames and creating a stack or mosaic of registered frames. Related auxiliary tasks, such as converting between different data formats, displaying images and calculating image statistics are also presented. In addition to the recipes and scripts, sufficient background material is presented to explain the procedures and techniques used. The treatment is deliberately practical rather than theoretical, in keeping with the aim of providing advice on the actual reduction of observations. Additional material outlines some of the differences between using conventional optical CCDs and the similar arrays used to observe at infrared wavelengths.

  17. Mosaic CCD method: A new technique for observing dynamics of cometary magnetospheres

    NASA Technical Reports Server (NTRS)

    Saito, T.; Takeuchi, H.; Kozuba, Y.; Okamura, S.; Konno, I.; Hamabe, M.; Aoki, T.; Minami, S.; Isobe, S.

    1992-01-01

    On April 29, 1990, the plasma tail of Comet Austin was observed with a CCD camera on the 105-cm Schmidt telescope at the Kiso Observatory of the University of Tokyo. The area of the CCD used in this observation is only about 1 sq cm. When this CCD is used on the 105-cm Schmidt telescope at the Kiso Observatory, the area corresponds to a narrow square view of 12 ft x 12 ft. By comparison with the photograph of Comet Austin taken by Numazawa (personal communication) on the same night, we see that only a small part of the plasma tail can be photographed at one time with the CCD. However, by shifting the view on the CCD after each exposure, we succeeded in imaging the entire length of the cometary magnetosphere of 1.6 x 10(exp 6) km. This new technique is called 'the mosaic CCD method'. In order to study the dynamics of cometary plasma tails, seven frames of the comet from the head to the tail region were twice imaged with the mosaic CCD method and two sets of images were obtained. Six microstructures, including arcade structures, were identified in both the images. Sketches of the plasma tail including microstructures are included.

  18. Dosimetry of heavy ions by use of CCD detectors

    NASA Technical Reports Server (NTRS)

    Schott, J. U.

    1994-01-01

    The design and the atomic composition of Charge Coupled Devices (CCD's) make them unique for investigations of single energetic particle events. As detector system for ionizing particles they detect single particles with local resolution and near real time particle tracking. In combination with its properties as optical sensor, particle transversals of single particles are to be correlated to any objects attached to the light sensitive surface of the sensor by simple imaging of their shadow and subsequent image analysis of both, optical image and particle effects, observed in affected pixels. With biological objects it is possible for the first time to investigate effects of single heavy ions in tissue or extinguished organs of metabolizing (i.e. moving) systems with a local resolution better than 15 microns. Calibration data for particle detection in CCD's are presented for low energetic protons and heavy ions.

  19. Sharpening advanced land imager multispectral data using a sensor model

    USGS Publications Warehouse

    Lemeshewsky, G.P.

    2005-01-01

    The Advanced Land Imager (ALI) instrument on NASA's Earth Observing One (EO-1) satellite provides for nine spectral bands at 30m ground sample distance (GSD) and a 10m GSD panchromatic band. This report describes an image sharpening technique where the higher spatial resolution information of the panchromatic band is used to increase the spatial resolution of ALI multispectral (MS) data. To preserve the spectral characteristics, this technique combines reported deconvolution deblurring methods for the MS data with highpass filter-based fusion methods for the Pan data. The deblurring process uses the point spread function (PSF) model of the ALI sensor. Information includes calculation of the PSF from pre-launch calibration data. Performance was evaluated using simulated ALI MS data generated by degrading the spatial resolution of high resolution IKONOS satellite MS data. A quantitative measure of performance was the error between sharpened MS data and high resolution reference. This report also compares performance with that of a reported method that includes PSF information. Preliminary results indicate improved sharpening with the method reported here.

  20. Aortic Stenosis, a Left Ventricular Disease: Insights from Advanced Imaging.

    PubMed

    Badiani, Sveeta; van Zalen, Jet; Treibel, Thomas A; Bhattacharyya, Sanjeev; Moon, James C; Lloyd, Guy

    2016-08-01

    Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence. It is increasingly clear that it is also a disease of the left ventricle (LV) rather than purely the aortic valve. The transition from left ventricular hypertrophy to fibrosis results in the eventual adverse effects on systolic and diastolic function. Appropriate selection of patients for aortic valve intervention is crucial, and current guidelines recommend aortic valve replacement in severe AS with symptoms or in asymptomatic patients with left ventricular ejection fraction (LVEF) <50 %. LVEF is not a sensitive marker and there are other parameters used in multimodality imaging techniques, including longitudinal strain, exercise stress echo and cardiac MRI that may assist in detecting subclinical and subtle LV dysfunction. These findings offer potentially better ways to evaluate patients, time surgery, predict recovery and potentially offer targets for specific therapies. This article outlines the pathophysiology behind the LV response to aortic stenosis and the role of advanced multimodality imaging in describing it. PMID:27384950

  1. Noise characterization of the linear CCD

    SciTech Connect

    McConaghy, C.F.

    1980-05-01

    Work in evaluating the noise performance of the linear charge-coupled devices (CCD) is summarized. The noise determines the minimum amplitude signal the CCD is capable of capturing and therefore is one of the prime parameters in determining dynamic range. The noise after correlated double sampling and correction of some ground loops will be shown equivalent to 150 rms electrons at the floating diffusion sensor on the CCD.

  2. 2048 pixel front illuminated linear CCD for spectroscopy

    NASA Astrophysics Data System (ADS)

    Wang, Chao-min; Liu, Chang-ju; Zheng, Yu; Li, Ping

    2009-07-01

    The charge couple device(CCD) used in spectroscopy requests good response to the wave bands between 190-1000 nm. The common measure to carry out UV response is phosphor coatings or back illuminated. Among them, phosphors are wavelength converters that convert short-wavelength light into the visible spectral region. This technology needs adding special process which not only raises cost, reduces yield, but also reduces the resolution of the image. Back illuminated is reducing CCD thickness to 15um which is thinner than the normal paper by mechanical polishing and chemical corrosion after completing the front processes of CCD. This technology needs special instrument, complex process , and the yield is also low. Both phosphor coatings and back illuminated have some disadvantages such as low space resolution, complex process, low yield, high cost etc. The CCD of traditional structure has no response to the wavelength less than 350nm, the reason is that the length of UV penetrating through Si is shallow, the penetrating length is only 6.5nm of 300nm UV, the shorter wavelength UV, the shallower penetrating length. The junction depth of normal CCD process is above 200nm, some realize shallow junction through molecular beam epitaxy, but the instrument is expensive and the cost is high. The photosensitive area of normal structure CCD adopting portrait P-N junction, light incidences from N area, N area can't be completely depleted because of the restrict of physics, photon can't arrive depletion area directly. On the basis of thorough analysis traditional UV CCD, horizontal P-N junction structure of Photosensitive area is put forward, whose depletion can reach the surface, the photon falls depletion area directly, which can effectively carry out the absorption of the UV light and the collection of photoelectron. As the latent absorption of Si3N4 to UV with less than 248nm wavelength, the Si3N4 passivation on the photosensitive area is take out. The improved 2048 elements

  3. Intensified-CCD focal plane detector for space applications A second generation

    NASA Technical Reports Server (NTRS)

    Torr, M. R.; Torr, D. G.; Baum, R.; Spielmaker, R.

    1986-01-01

    An intensified-CCD detector system developed for space applications from commercially available components is described. This detector uses components which are readily available and are mechanically, thermally, and optically coupled to produce the final compact system. The CCD is cooled using a Peltier-effect thermoelectric cooler to reduce thermal noise. The image is formed on the photocathode of a proximity-focused image intensifier and is transferred fiber-optically from the intensifier to the CDD. Various photocathode and window materials are used to optimize the system for use within the wavelength range extending from the far UV to the near IR. The basic design, including the image intensifier, intensifier-CCD interface, CCD array, cooling, electronics, and mounting, and the detector performance are described in detail.

  4. Data acquisition and control system for high-performance large-area CCD systems

    NASA Astrophysics Data System (ADS)

    Afanasieva, I. V.

    2015-04-01

    Astronomical CCD systems based on second-generation DINACON controllers were developed at the SAO RAS Advanced Design Laboratory more than seven years ago and since then have been in constant operation at the 6-meter and Zeiss-1000 telescopes. Such systems use monolithic large-area CCDs. We describe the software developed for the control of a family of large-area CCD systems equipped with a DINACON-II controller. The software suite serves for acquisition, primary reduction, visualization, and storage of video data, and also for the control, setup, and diagnostics of the CCD system.

  5. The Advanced X-ray Spectroscopy and Imaging Observatory (AXSIO)

    NASA Technical Reports Server (NTRS)

    White, Nicholas E.; Bookbinder, Jay; Petre, Robert; Smith, Randall; Ptak, Andrew; Tananbaum, Harvey; Garcia, Michael

    2012-01-01

    Following recommendations from the 2010 "New Worlds, New Horizons" (NWNH) report, the Advanced X-ray Spectroscopy and Imaging Observatory (AXSIO) concept streamlines the International X-ray Observatory (IXO) mission to concentrate on the science objectives that are enabled by high-resolution spectroscopic capabilities. AXSIO will trace orbits close to the event horizon of black holes, measure black hole spin for tens of supermassive black holes (SMBH), use spectroscopy to characterize outflows and the environment of AGN during their peak activity, observe 5MBH out to redshift z=6, map bulk motions and turbulence in galaxy clusters, find the missing baryons in the cosmic web using background quasars, and observe the process of cosmic feedback where black holes and supernovae inject energy on galactic and intergalactic scales. These measurements are enabled by a 0.9 sq m collecting area at 1.25 keV, a micro calorimeter array providing high-resolution spectroscopic imaging and a deployable high efficiency grating spectrometer. AXSIO delivers a 30-fold increase in effective area for high resolution spectroscopy. The key simplifications are guided by recommendations in the NWNH panel report include a reduction in focal length from 20m to 10m, eliminating the extendable optical bench, and a reduction in the instrument complement from six to two, avoiding a movable instrument platform. A focus on spectroscopic science allows the spatial resolution requirement to be relaxed to 10 arc sec (with a 5 arc sec goal). These simplifications decrease the total mission cost to under the $2B cost to NASA recommended by NWNH. AXSIO will be available to the entire astronomical community with observing allocations based on peer-review.

  6. The Advanced X-ray Spectroscopy and Imaging Observatory (AXSIO)

    NASA Astrophysics Data System (ADS)

    White, Nicholas E.; Bookbinder, Jay; Petre, Robert; Smith, Randall; Ptak, Andrew; Tananbaum, Harvey; Bregman, Joel; Garcia, Michael; Zhang, W.; Kelley, R.; Kilbourne, C.; Bandler, S.

    2012-09-01

    Following recommendations from the 2010 "New Worlds, New Horizons" (NWNH) report, the Advanced X-ray Spectroscopy and Imaging Observatory (AXSIO) concept streamlines the International X-ray Observatory (IXO) mission to concentrate on the science objectives that are enabled by high-resolution spectroscopic capabilities. AXSIO will trace orbits close to the event horizon of black holes, measure black hole spin for tens of supermassive black holes (SMBH), use spectroscopy to characterize outflows and the environment of AGN during their peak activity, observe SMBH out to redshift z=6, map bulk motions and turbulence in galaxy clusters, find the missing baryons in the cosmic web using background quasars, and observe the process of cosmic feedback where black holes and supernovae inject energy on galactic and intergalactic scales. These measurements are enabled by a 0.9 sq m collecting area at 1.25 keV, a microcalorimeter array providing high-resolution spectroscopic imaging and a deployable high efficiency grating spectrometer. AXSIO delivers a 30-fold increase in effective area for high-resolution spectroscopy. The key simplifications are guided by recommendations in the NWNH panel report include a reduction in focal length from 20m to 10m, eliminating the extendable optical bench, and a reduction in the instrument complement from six to two, avoiding a movable instrument platform. A focus on spectroscopic science allows the spatial resolution requirement to be relaxed to 10 arcsec (with a 5 arc sec goal). These simplifications decrease the total mission cost to under the $2B cost to NASA recommended by NWNH. AXSIO will be available to the entire astronomical community with observing allocations based on peer- review.

  7. The 2060 Chiron: CCD photometry

    NASA Technical Reports Server (NTRS)

    Bus, Schelte J.; Bowell, Edward; Harris, Alan W.

    1987-01-01

    R-band CCD photometry of 2060 was carried out on nine nights in Nov. and Dec. 1986. The rotation period is 5.9181 + or - 0.0003 hr and the peak to peak lightcurve amplitude is 0.088 + or - 0.0003 mag. Photometric parameters are H sub R = 6.24 + or - 0.02 mag and G sub R = + or - 0.15, though formal errors may not be realistic. The lightcurve has two pairs of extrema, but its asymmetry, as evidenced by the presence of significant odd Fourier harmonics, suggests macroscopic surface irregularities and/or the presence of some large scale albedo variegation. The observational rms residual is + or - 0.015 mag. On time scales from minutes to days there is no evidence for nonperiodic (cometary) brightness changes at the level of a few millimagnitudes.

  8. A collaborative enterprise for multi-stakeholder participation in the advancement of quantitative imaging.

    PubMed

    Buckler, Andrew J; Bresolin, Linda; Dunnick, N Reed; Sullivan, Daniel C

    2011-03-01

    Medical imaging has seen substantial and rapid technical advances during the past decade, including advances in image acquisition devices, processing and analysis software, and agents to enhance specificity. Traditionally, medical imaging has defined anatomy, but increasingly newer, more advanced, imaging technologies provide biochemical and physiologic information based on both static and dynamic modalities. These advanced technologies are important not only for detecting disease but for characterizing and assessing change of disease with time or therapy. Because of the rapidity of these advances, research to determine the utility of quantitative imaging in either clinical research or clinical practice has not had time to mature. Methods to appropriately develop, assess, regulate, and reimburse must be established for these advanced technologies. Efficient and methodical processes that meet the needs of stakeholders in the biomedical research community, therapeutics developers, and health care delivery enterprises will ultimately benefit individual patients. To help address this, the authors formed a collaborative program-the Quantitative Imaging Biomarker Alliance. This program draws from the very successful precedent set by the Integrating the Healthcare Enterprise effort but is adapted to the needs of imaging science. Strategic guidance supporting the development, qualification, and deployment of quantitative imaging biomarkers will lead to improved standardization of imaging tests, proof of imaging test performance, and greater use of imaging to predict the biologic behavior of tissue and monitor therapy response. These, in turn, confer value to corporate stakeholders, providing incentives to bring new and innovative products to market. PMID:21339352

  9. Advanced imaging techniques for the study of plant growth and development

    PubMed Central

    Sozzani, Rosangela; Busch, Wolfgang; Spalding, Edgar P.; Benfey, Philip N.

    2014-01-01

    A variety of imaging methodologies are being used to collect data for quantitative studies of plant growth and development from living plants. Multi-level data, from macroscopic to molecular, and from weeks to seconds, can be acquired. Furthermore, advances in parallelized and automated image acquisition enable the throughput to capture images from large populations of plants under specific growth conditions. Image-processing capabilities allow for 3D or 4D reconstruction of image data and automated quantification of biological features. These advances facilitate the integration of imaging data with genome-wide molecular data to enable systems-level modeling. PMID:24434036

  10. Advanced Reservoir Imaging Using Frequency-Dependent Seismic Attributes

    SciTech Connect

    Fred Hilterman; Tad Patzek; Gennady Goloshubin; Dmitriy Silin; Charlotte Sullivan; Valeri Korneev

    2007-12-31

    Our report concerning advanced imaging and interpretation technology includes the development of theory, the implementation of laboratory experiments and the verification of results using field data. We investigated a reflectivity model for porous fluid-saturated reservoirs and demonstrated that the frequency-dependent component of the reflection coefficient is asymptotically proportional to the reservoir fluid mobility. We also analyzed seismic data using different azimuths and offsets over physical models of fractures filled with air and water. By comparing our physical model synthetics to numerical data we have identified several diagnostic indicators for quantifying the fractures. Finally, we developed reflectivity transforms for predicting pore fluid and lithology using rock-property statistics from 500 reservoirs in both the shelf and deep-water Gulf of Mexico. With these transforms and seismic AVO gathers across the prospect and its down-dip water-equivalent reservoir, fluid saturation can be estimated without a calibration well that ties the seismic. Our research provides the important additional mechanisms to recognize, delineate, and validate new hydrocarbon reserves and assist in the development of producing fields.

  11. Recent Advances in Metabolic Profiling And Imaging of Prostate Cancer

    PubMed Central

    Thapar, Roopa; Titus, Mark A

    2015-01-01

    Cancer is a metabolic disease. Cancer cells, being highly proliferative, show significant alterations in metabolic pathways such as glycolysis, respiration, the tricarboxylic acid (TCA) cycle, oxidative phosphorylation, lipid metabolism, and amino acid metabolism. Metabolites like peptides, nucleotides, products of glycolysis, the TCA cycle, fatty acids, and steroids can be an important read out of disease when characterized in biological samples such as tissues and body fluids like urine, serum, etc. The cancer metabolome has been studied since the 1960s by analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. Current research is focused on the identification and validation of biomarkers in the cancer metabolome that can stratify high-risk patients and distinguish between benign and advanced metastatic forms of the disease. In this review, we discuss the current state of prostate cancer metabolomics, the biomarkers that show promise in distinguishing indolent from aggressive forms of the disease, the strengths and limitations of the analytical techniques being employed, and future applications of metabolomics in diagnostic imaging and personalized medicine of prostate cancer. PMID:25632377

  12. Recent advances in imaging crustal fault zones: a review

    NASA Astrophysics Data System (ADS)

    Yang, Hongfeng

    2015-04-01

    Crustal faults usually have a fault core and surrounding regions of brittle damage, forming a low-velocity zone (LVZ) in the immediate vicinity of the main slip interface. The LVZ may amplify ground motion, influence rupture propagation, and hold important information of earthquake physics. A number of geophysical and geodetic methods have been developed to derive high-resolution structure of the LVZ. Here, I review a few recent approaches, including ambient noise cross-correlation on dense across-fault arrays and GPS recordings of fault-zone trapped waves. Despite the past efforts, many questions concerning the LVZ structure remain unclear, such as the depth extent of the LVZ. High-quality data from larger and denser arrays and new seismic imaging technique using larger portion of recorded waveforms, which are currently under active development, may be able to better resolve the LVZ structure. In addition, effects of the along-strike segmentation and gradational velocity changes across the boundaries between the LVZ and the host rock on rupture propagation should be investigated by conducting comprehensive numerical experiments. Furthermore, high-quality active sources such as recently developed large-volume air-gun arrays provide a powerful tool to continuously monitor temporal changes of fault-zone properties, and thus can advance our understanding of fault zone evolution.

  13. Radiometric calibration of the EO-1 Advanced Land Imager

    NASA Astrophysics Data System (ADS)

    Mendenhall, Jeffrey A.; Lencioni, Donald E.; Parker, Alexander C.

    1999-09-01

    The radiometric calibration of the Earth Observation 1 Advanced Land Imager (EO-1 ALI) was completed in the Spring of 1999 at Lincoln Laboratory. This calibration was conducted with the ALI as a fully assembled instrument in a thermal vacuum chamber at operation temperatures. The ALI was calibrated radiometrically at the system level from 0 to > 100 percent Earth-equivalent albedo using a combination of internal and external halogen and Xenon lamps attached to a large integrating sphere. Absolute radiometric calibration was achieved by measuring the output of the integrating sphere at each radiance level prior to ALI illumination using a NIST-traceable spectroradiometer. Additional radiometric characterization of this instrument was obtained from data collected using a collimator designed for the spectral calibration of the ALI. In this paper we review the techniques employed during radiometric calibration and present the measured gain, linearity, offset, signal-to- noise ratio and polarization sensitivity of each pixel. The testing result of a novel, in-flight solar calibration technique are also discussed. Finally, the results from a Lincoln Laboratory/Goddard Space Flight Center Landsat transfer radiometric study are presented.

  14. Earth Observing-1 Advanced Land Imager: Imaging Performance On-Orbit

    NASA Technical Reports Server (NTRS)

    Hearn, D. R.

    2002-01-01

    This report analyzes the on-orbit imaging performance of the Advanced Land Imager (ALI) on the Earth Observing-1 satellite. The pre-flight calibrations are first summarized. The methods used to reconstruct and geometrically correct the image data from this push-broom sensor are described. The method used here does not refer to the position and attitude telemetry from the spacecraft. Rather, it is assumed that the image of the scene moves across the focal plane with a constant velocity, which can be ascertained from the image data itself. Next, an assortment of the images so reconstructed is presented. Color images sharpened with the 10-m panchromatic band data are shown, and the algorithm for producing them from the 30-m multispectral data is described. The approach taken for assessing spatial resolution is to compare the sharpness of features in the on-orbit image data with profiles predicted on the basis of the pre-flight calibrations. A large assortment of bridge profiles is analyzed, and very good fits to the predicted shapes are obtained. Lunar calibration scans are analyzed to examine the sharpness of the edge-spread function at the limb of the moon. The darkness of the space beyond the limb is better for this purpose than anything that could be simulated on the ground. From these scans, we find clear evidence of scattering in the optical system, as well as some weak ghost images. Scans of planets and stars are also analyzed. Stars are useful point sources of light at all wavelengths, and delineate the point-spread functions of the system. From a quarter-speed scan over the Pleiades, we find that the ALI can detect 6th magnitude stars. The quality of the reconstructed images verifies the capability of the ALI to produce Landsat-type multi spectral data. The signal-to-noise and panchromatic spatial resolution are considerably superior to those of the existing Landsat sensors. The spatial resolution is confirmed to be as good as it was designed to be.

  15. Robotic CCD microscope for enhanced crystal recognition

    DOEpatents

    Segelke, Brent W.; Toppani, Dominique

    2007-11-06

    A robotic CCD microscope and procedures to automate crystal recognition. The robotic CCD microscope and procedures enables more accurate crystal recognition, leading to fewer false negative and fewer false positives, and enable detection of smaller crystals compared to other methods available today.

  16. Status Of Sofradir IR-CCD Detectors

    NASA Astrophysics Data System (ADS)

    Tribolet, Philippe; Radisson, Patrick

    1988-05-01

    The topics of this paper deal with the IR-CCD detectors manufactured by SOFRADIR the new French joint venture. Description of the IRCCD technology and the advantages of this approach are given. In conclusion, some IR-CCD typical results are given.

  17. Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging

    PubMed Central

    Shimojo, Masafumi; Higuchi, Makoto; Suhara, Tetsuya; Sahara, Naruhiko

    2015-01-01

    The rapid progress in advanced imaging technologies has expanded our toolbox for monitoring a variety of biological aspects in living subjects including human. In vivo radiological imaging using small chemical tracers, such as with positron emission tomography, represents an especially vital breakthrough in the efforts to improve our understanding of the complicated cascade of neurodegenerative disorders including Alzheimer's disease (AD), and it has provided the most reliable visible biomarkers for enabling clinical diagnosis. At the same time, in combination with genetically modified animal model systems, the most recent innovation of fluorescence imaging is helping establish diverse applications in basic neuroscience research, from single-molecule analysis to animal behavior manipulation, suggesting the potential utility of fluorescence technology for dissecting the detailed molecular-based consequence of AD pathophysiology. In this review, our primary focus is on a current update of PET radiotracers and fluorescence indicators beneficial for understanding the AD cascade, and discussion of the utility and pitfalls of those imaging modalities for future translational research applications. We will also highlight current cutting-edge genetic approaches and discuss how to integrate individual technologies for further potential innovations. PMID:26733795

  18. Measuring method of CCD installation verticality based on own system of intelligent laser cutting machine

    NASA Astrophysics Data System (ADS)

    Zhong, Ping; Lu, Hongbo; Liu, Fuguo; Chen, Ziyuan; He, Pan; Jiang, Xueshi

    2016-01-01

    The installation verticality between the optical axis of CCD and the working plane of intelligent laser cutting machine is one of the most important factors in determining image quality of the processed object which comes from computer vision system. In this paper, an innovative method is proposed which can make it possible to use the equipment of own system of intelligent laser cutting machine to detect installation verticality between the optical axis of CCD and the working plane. Experimental results show that the method presented in this paper is a feasible solution for measuring the installation verticality between the optical axis of CCD and the working plane of intelligent laser cutting machine.

  19. Advanced signal processing

    NASA Astrophysics Data System (ADS)

    Creasey, D. J.

    1985-12-01

    A collection of papers on advanced signal processing in radar, sonar, and communications is presented. The topics addressed include: transmitter aerials, high-power amplifier design for active sonar, radar transmitters, receiver array technology for sonar, new underwater acoustic detectors, diversity techniques in communications receivers, GaAs IC amplifiers for radar and communication receivers, integrated optical techniques for acoustooptic receivers, logarithmic receivers, CCD processors for sonar, acoustooptic correlators, designing in silicon, very high performance integrated circuits, and digital filters. Also discussed are: display types, scan converters in sonar, display ergonomics, simulators, high throughput sonar processors, optical fiber systems for signal processing, satellite communications, VLSI array processor for image and signal processing, ADA, future of cryogenic devices for signal processing applications, advanced image understanding, and VLSI architectures for real-time image processing.

  20. The Advanced Gamma-Ray Imaging System (AGIS): Science Highlights

    SciTech Connect

    Buckley, J.; Coppi, P.; Digel, S.; Funk, S.; Krawczynski, H.; Krennrich, F.; Pohl, M.; Romani, R.; Vassiliev, V.; /UCLA

    2011-11-21

    The Advanced Gamma-ray Imaging System (AGIS), a future gamma-ray telescope consisting of an array of {approx}50 atmospheric Cherenkov telescopes distributed over an area of {approx}1 km{sup 2}, will provide a powerful new tool for exploring the high-energy universe. The order-of-magnitude increase in sensitivity and improved angular resolution could provide the first detailed images of {gamma}-ray emission from other nearby galaxies or galaxy clusters. The large effective area will provide unprecedented sensitivity to short transients (such as flares from AGNs and GRBs) probing both intrinsic spectral variability (revealing the details of the acceleration mechanism and geometry) as well as constraining the high-energy dispersion in the velocity of light (probing the structure of spacetime and Lorentz invariance). A wide field of view ({approx}4 times that of current instruments) and excellent angular resolution (several times better than current instruments) will allow for an unprecedented survey of the Galactic plane, providing a deep unobscured survey of SNRs, X-ray binaries, pulsar-wind nebulae, molecular cloud complexes and other sources. The differential flux sensitivity of {approx}10{sup -13} erg cm{sup -2} sec{sup -1} will rival the most sensitive X-ray instruments for these extended Galactic sources. The excellent capabilities of AGIS at energies below 100 GeV will provide sensitivity to AGN and GRBs out to cosmological redshifts, increasing the number of AGNs detected at high energies from about 20 to more than 100, permitting population studies that will provide valuable insights into both a unified model for AGN and a detailed measurement of the effects of intergalactic absorption from the diffuse extragalactic background light. A new instrument with fast-slewing wide-field telescopes could provide detections of a number of long-duration GRBs providing important physical constraints from this new spectral component. The new array will also have excellent

  1. Design, development, and performance of the STEREO SECCHI CCD cameras

    NASA Astrophysics Data System (ADS)

    Waltham, Nick; Eyles, Chris

    2007-09-01

    We report the design, development and performance of the SECCHI (Sun Earth Connection Coronal and Heliospheric Investigation) CCD camera electronics on NASA's Solar Terrestrial Relations Observatory (STEREO). STEREO consists of two nearly identical space-based observatories; one ahead of Earth in its orbit, the other trailing behind to provide the first-ever stereoscopic (3D) measurements to study the Sun and the nature of its coronal mass ejections. The SECCHI instrument suite consists of five telescopes that will observe the solar corona, and inner heliosphere all the way from the surface of the Sun to the orbit of the Earth, and beyond. Each telescope contains a large-format science-grade CCD; two within the Heliospheric Imager (HI) instrument, and three in a separate instrument package (SCIP) consisting of two coronagraphs and an EUV imager. The CCDs are operated from two Camera Electronics Boxes. Constraints on the size, mass, and power available for the camera electronics required the development of a miniaturised solution employing digital and mixed-signal ASICs, FPGAs, and compact surface-mount construction. Operating more than one CCD from a single box also provides economy on the number of DC-DC converters and interface electronics required. We describe the requirements for the overall design and implementation, and in particular the design and performance of the camera's space-saving mixed-signal CCD video processing ASIC. The performance of the camera is reviewed together with sample images obtained since the STEREO mission was successfully launched on October 25 2006 from Cape Canaveral.

  2. Integration design of FPGA software for a miniaturizing CCD remote sensing camera

    NASA Astrophysics Data System (ADS)

    Yin, Na; Li, Qiang; Rong, Peng; Lei, Ning; Wan, Min

    2014-09-01

    Video signal processor (VSP) is an important part for CCD remote sensing cameras, and also is the key part of light miniaturization design for cameras. We need to apply FPGAs to improve the level of integration for simplifying the video signal processor circuit. This paper introduces an integration design of FPGA software for video signal processor in a certain space remote sensing camera in detail. This design has accomplished the functions of integration in CCD timing control, integral time control, CCD data formatting and CCD image processing and correction on one single FPGA chip, which resolved the problem for miniaturization of video signal processor in remote sensing cameras. Currently, this camera has already launched successfully and obtained high quality remote sensing images, which made contribution to the miniaturizing remote sensing camera.

  3. Advances in Clinical and Biomedical Applications of Photoacoustic Imaging

    PubMed Central

    Su, Jimmy L.; Wang, Bo; Wilson, Katheryne E.; Bayer, Carolyn L.; Chen, Yun-Sheng; Kim, Seungsoo; Homan, Kimberly A.; Emelianov, Stanislav Y.

    2010-01-01

    Importance of the field Photoacoustic imaging is an imaging modality that derives image contrast from the optical absorption coefficient of the tissue being imaged. The imaging technique is able to differentiate between healthy and diseased tissue with either deeper penetration or higher resolution than other functional imaging modalities currently available. From a clinical standpoint, photoacoustic imaging has demonstrated safety and effectiveness in diagnosing diseased tissue regions using either endogenous tissue contrast or exogenous contrast agents. Furthermore, the potential of photoacoustic imaging has been demonstrated in various therapeutic interventions ranging from drug delivery and release to image-guided therapy and monitoring. Areas covered in this review This article reviews the current state of photoacoustic imaging in biomedicine from a technological perspective, highlights various biomedical and clinical applications of photoacoustic imaging, and gives insights on future directions. What the reader will gain Readers will learn about the various applications of photoacoustic imaging, as well as the various contrast agents that can be used to assist photoacoustic imaging. This review will highlight both pre-clinical and clinical uses for photoacoustic imaging, as well as discuss some of the challenges that must be addressed to move photoacoustic imaging into the clinical realm. Take home message Photoacoustic imaging offers unique advantages over existing imaging modalities. The imaging field is broad with many exciting applications for detecting and diagnosing diseased tissue or processes. Photoacoustics is also used in therapeutic applications to identify and characterize the pathology and then to monitor the treatment. Although the technology is still in its infancy, much work has been done in the pre-clinical arena, and photoacoustic imaging is fast approaching the clinical setting. PMID:21344060

  4. Cryostat and CCD for MEGARA at GTC

    NASA Astrophysics Data System (ADS)

    Castillo-Domínguez, E.; Ferrusca, D.; Tulloch, S.; Velázquez, M.; Carrasco, E.; Gallego, J.; Gil de Paz, A.; Sánchez, F. M.; Vílchez Medina, J. M.

    2012-09-01

    MEGARA (Multi-Espectrógrafo en GTC de Alta Resolución para Astronomía) is the new integral field unit (IFU) and multi-object spectrograph (MOS) instrument for the GTC. The spectrograph subsystems include the pseudo-slit, the shutter, the collimator with a focusing mechanism, pupil elements on a volume phase holographic grating (VPH) wheel and the camera joined to the cryostat through the last lens, with a CCD detector inside. In this paper we describe the full preliminary design of the cryostat which will harbor the CCD detector for the spectrograph. The selected cryogenic device is an LN2 open-cycle cryostat which has been designed by the "Astronomical Instrumentation Lab for Millimeter Wavelengths" at INAOE. A complete description of the cryostat main body and CCD head is presented as well as all the vacuum and temperature sub-systems to operate it. The CCD is surrounded by a radiation shield to improve its performance and is placed in a custom made mechanical mounting which will allow physical adjustments for alignment with the spectrograph camera. The 4k x 4k pixel CCD231 is our selection for the cryogenically cooled detector of MEGARA. The characteristics of this CCD, the internal cryostat cabling and CCD controller hardware are discussed. Finally, static structural finite element modeling and thermal analysis results are shown to validate the cryostat model.

  5. Photometric correction for an optical CCD-based system based on the sparsity of an eight-neighborhood gray gradient.

    PubMed

    Zhang, Yuzhong; Zhang, Yan

    2016-07-01

    In an optical measurement and analysis system based on a CCD, due to the existence of optical vignetting and natural vignetting, photometric distortion, in which the intensity falls off away from the image center, affects the subsequent processing and measuring precision severely. To deal with this problem, an easy and straightforward method used for photometric distortion correction is presented in this paper. This method introduces a simple polynomial fitting model of the photometric distortion function and employs a particle swarm optimization algorithm to get these model parameters by means of a minimizing eight-neighborhood gray gradient. Compared with conventional calibration methods, this method can obtain the profile information of photometric distortion from only a single common image captured by the optical CCD-based system, with no need for a uniform luminance area source used as a standard reference source and relevant optical and geometric parameters in advance. To illustrate the applicability of this method, numerical simulations and photometric distortions with different lens parameters are evaluated using this method in this paper. Moreover, the application example of temperature field correction for casting billets also demonstrates the effectiveness of this method. The experimental results show that the proposed method is able to achieve the maximum absolute error for vignetting estimation of 0.0765 and the relative error for vignetting estimation from different background images of 3.86%. PMID:27409217

  6. The Crimean CCD telescope for the asteroid observations

    NASA Astrophysics Data System (ADS)

    Chernykh, Nikolaj; Rumyantsev, Vasilij

    2002-11-01

    The old 64-cm Richter-Slefogt telescope (F=90 cm) of the Crimean Astrophysical Observatory was reconstructed and equipped with the St-8 CCD camera supplied by the Planetary Society as the Eugene Shoemaker Near Earth Object Grant. The first observations of minor planets and comets were made with the telescope in 2000. The CCD matrix of St-8 camera in the focus of our telescope covers field of 52'.7×35'.1. With 120-second exposure we obtain the images of stars up to the limiting magnitude of 20.5 mag within S/N=3. The first phase of automation of the telescope was completed in May of 2002. According to our estimations, the telescope will be able to cover the sky area of 20 square deg with threefold overlapping during the night. The software for object localization, image parameters determination, stars identification, astrometric reduction, identification and cataloguing of asteroids is worked up. The first observation results obtained with the 64-cm CCD telescope are discussed.

  7. Use of CCD sensors in flow cytometry for nonimaging applications

    NASA Astrophysics Data System (ADS)

    Beisker, Wolfgang

    1997-05-01

    The use of charge coupled devices (CCDs) as non-imaging sensors in flow cytometric systems to replace the classical photomultplier tubes (PMTs) is very advantageous: the quantum efficiency of the CCDs is about 5 to 10 times higher as for PMTs, the charge storage capability of CCDs avoids analogue processing of the fluorescence signals, the dynamic range is up to 18 bits and the fluorescence intensity at different wavelengths can be recorded on the same chip. In this report a full frame CCD imager is used in a thermoelectrically cooled environment. The output signal for the CCD is digitized with a 12-bit ADC and the data are sorted as list-mode data typically used in flow cytometric work. The performance of the system is demonstrated with DNA staining of mammalian cells with acridine-orange, propidium iodide and ethidium bromide. DNA histograms comparable with standard flow cytometry are recorded. From the same data set pulse-widths histograms can be processed and used for doublet discrimination. The high quantum efficiency of the CCD sensors is of special interest for fluorescing dyes in the dark red or near IR wavelength range.

  8. Focusing optics of a parallel beam CCD optical tomography apparatus for 3D radiation gel dosimetry.

    PubMed

    Krstajić, Nikola; Doran, Simon J

    2006-04-21

    Optical tomography of gel dosimeters is a promising and cost-effective avenue for quality control of radiotherapy treatments such as intensity-modulated radiotherapy (IMRT). Systems based on a laser coupled to a photodiode have so far shown the best results within the context of optical scanning of radiosensitive gels, but are very slow ( approximately 9 min per slice) and poorly suited to measurements that require many slices. Here, we describe a fast, three-dimensional (3D) optical computed tomography (optical-CT) apparatus, based on a broad, collimated beam, obtained from a high power LED and detected by a charged coupled detector (CCD). The main advantages of such a system are (i) an acquisition speed approximately two orders of magnitude higher than a laser-based system when 3D data are required, and (ii) a greater simplicity of design. This paper advances our previous work by introducing a new design of focusing optics, which take information from a suitably positioned focal plane and project an image onto the CCD. An analysis of the ray optics is presented, which explains the roles of telecentricity, focusing, acceptance angle and depth-of-field (DOF) in the formation of projections. A discussion of the approximation involved in measuring the line integrals required for filtered backprojection reconstruction is given. Experimental results demonstrate (i) the effect on projections of changing the position of the focal plane of the apparatus, (ii) how to measure the acceptance angle of the optics, and (iii) the ability of the new scanner to image both absorbing and scattering gel phantoms. The quality of reconstructed images is very promising and suggests that the new apparatus may be useful in a clinical setting for fast and accurate 3D dosimetry. PMID:16585845

  9. CCD Photometry of bright stars using objective wire mesh

    SciTech Connect

    Kamiński, Krzysztof; Zgórz, Marika; Schwarzenberg-Czerny, Aleksander

    2014-06-01

    Obtaining accurate photometry of bright stars from the ground remains problematic due to the danger of overexposing the target and/or the lack of suitable nearby comparison stars. The century-old method of using objective wire mesh to produce multiple stellar images seems promising for the precise CCD photometry of such stars. Furthermore, our tests on β Cep and its comparison star, differing by 5 mag, are very encouraging. Using a CCD camera and a 20 cm telescope with the objective covered by a plastic wire mesh, in poor weather conditions, we obtained differential photometry with a precision of 4.5 mmag per two minute exposure. Our technique is flexible and may be tuned to cover a range as big as 6-8 mag. We discuss the possibility of installing a wire mesh directly in the filter wheel.

  10. CCD Photometry of Bright Stars Using Objective Wire Mesh

    NASA Astrophysics Data System (ADS)

    Kamiński, Krzysztof; Schwarzenberg-Czerny, Aleksander; Zgórz, Marika

    2014-06-01

    Obtaining accurate photometry of bright stars from the ground remains problematic due to the danger of overexposing the target and/or the lack of suitable nearby comparison stars. The century-old method of using objective wire mesh to produce multiple stellar images seems promising for the precise CCD photometry of such stars. Furthermore, our tests on β Cep and its comparison star, differing by 5 mag, are very encouraging. Using a CCD camera and a 20 cm telescope with the objective covered by a plastic wire mesh, in poor weather conditions, we obtained differential photometry with a precision of 4.5 mmag per two minute exposure. Our technique is flexible and may be tuned to cover a range as big as 6-8 mag. We discuss the possibility of installing a wire mesh directly in the filter wheel.

  11. SCP -- A Simple CCD Processing Package

    NASA Astrophysics Data System (ADS)

    Lewis, J. R.

    This note describes a small set of programs, written at RGO, which deal with basic CCD frame processing (e.g. bias subtraction, flat fielding, trimming etc.). The need to process large numbers of CCD frames from devices such as FOS or ISIS in order to extract spectra has prompted the writing of routines which will do the basic hack-work with a minimal amount of interaction from the user. Although they were written with spectral data in mind, there are no ``spectrum-specific'' features in the software which means they can be applied to any CCD data.

  12. Development of CCD controller for scientific application

    NASA Astrophysics Data System (ADS)

    Khan, M. S.; Pathan, F. M.; Shah, U. V., Prof; Makwana, D. H., Prof; Anandarao, B. G., Prof

    2010-02-01

    Photoelectric equipment has wide applications such as spectroscopy, temperature measurement in infrared region and in astronomical research etc. A photoelectric transducer converts radiant energy into electrical energy. There are two types of photoelectric transducers namely photo-multiplier tube (PMT) and charged couple device (CCD) are used to convert radiant energy into electrical signal. Now the entire modern instruments use CCD technology. We have designed and developed a CCD camera controller using camera chip CD47-10 of Marconi which has 1K × 1K pixel for space application only.

  13. Advanced magneto-optical microscopy: Imaging from picoseconds to centimeters - imaging spin waves and temperature distributions (invited)

    NASA Astrophysics Data System (ADS)

    Urs, Necdet Onur; Mozooni, Babak; Mazalski, Piotr; Kustov, Mikhail; Hayes, Patrick; Deldar, Shayan; Quandt, Eckhard; McCord, Jeffrey

    2016-05-01

    Recent developments in the observation of magnetic domains and domain walls by wide-field optical microscopy based on the magneto-optical Kerr, Faraday, Voigt, and Gradient effect are reviewed. Emphasis is given to the existence of higher order magneto-optical effects for advanced magnetic imaging. Fundamental concepts and advances in methodology are discussed that allow for imaging of magnetic domains on various length and time scales. Time-resolved imaging of electric field induced domain wall rotation is shown. Visualization of magnetization dynamics down to picosecond temporal resolution for the imaging of spin-waves and magneto-optical multi-effect domain imaging techniques for obtaining vectorial information are demonstrated. Beyond conventional domain imaging, the use of a magneto-optical indicator technique for local temperature sensing is shown.

  14. The CCD/Transit Instrument (CTI) data-analysis system

    NASA Technical Reports Server (NTRS)

    Cawson, M. G. M.; Mcgraw, J. T.; Keane, M. J.

    1986-01-01

    An account is given of the Kitt Peak CCD/Transit Instrument's software for the automated archiving, analysis, and interrogation of each observation night's nearly 450 Mbytes of image data. The analysis phase is performed by a pair of linked algorithms, one of which operates on the absolute pixel-values and the other on the spatial derivative of the data, so that both isolated and merged images are reliably detected in a single pass. This is in due course followed by the automatic comparison of each new detection with a set of predefined templates in parameter space, in order to find such interesting objects as supernovae, quasars, and variable stars.

  15. Lock-in CCD and the convolver CCD: applications of exposure-concurrent photocharge transfer in optical metrology and machine vision

    NASA Astrophysics Data System (ADS)

    Seitz, Peter; Spirig, Thomas; Vietze, Oliver; Metzler, Peter

    1995-04-01

    Two types of image sensors are described that exploit the CCD's capability of spatially moving photocharge simultaneously with the exposure to a scene. The lock-in CCD is a two- dimensional array of pixels, each of which is a synchronous detector for oscillating optical wave fields with a spatially varying distribution of phase, amplitude and background offset. Main applications of this novel CCD type are in time-of-flight and heterodyne interferometric range imaging without moving parts. The convolver CCD consists of a two-dimensional array of pixels, connected with their nearest neighbors through short CCD lines, with which photocharge can be transferred vertically and horizontally during the exposure. By suitably timing these charge shifts, freely programmable convolutions with kernels of arbitrary size become possible. Tap weight accuracies of typically 2% of the largest tap value have been obtained for a variety of linear filters that are commonly used in machine vision. An integral part of these CCDs is a programmable, microcontroller-based driver system, capable of generating dynamic pulse sequences and driving virtually any image sensor available commercially or custom designed for special applications.

  16. CCD TV focal plane guider development and comparison to SIRTF applications

    NASA Technical Reports Server (NTRS)

    Rank, David M.

    1989-01-01

    It is expected that the SIRTF payload will use a CCD TV focal plane fine guidance sensor to provide acquisition of sources and tracking stability of the telescope. Work has been done to develop CCD TV cameras and guiders at Lick Observatory for several years and have produced state of the art CCD TV systems for internal use. NASA decided to provide additional support so that the limits of this technology could be established and a comparison between SIRTF requirements and practical systems could be put on a more quantitative basis. The results of work carried out at Lick Observatory which was designed to characterize present CCD autoguiding technology and relate it to SIRTF applications is presented. Two different design types of CCD cameras were constructed using virtual phase and burred channel CCD sensors. A simple autoguider was built and used on the KAO, Mt. Lemon and Mt. Hamilton telescopes. A video image processing system was also constructed in order to characterize the performance of the auto guider and CCD cameras.

  17. A novel calibration method of CCD camera for LAMOST

    NASA Astrophysics Data System (ADS)

    Gu, Yonggang; Jin, Yi; Zhai, Chao

    2012-09-01

    Large Sky Area Multi-object Fiber Spectroscopic Telescope - LAMOST, with a 1.75m-diameter focal plane on which 4000 optical fibers are arranged, is one of major scientific projects in China. During the surveying process of LAMOST, the optical imaging system makes the astrometric objects be imaged in the focal plane, and the optical fiber positioning system controls the 4000 fibers to be aligned with these objects and obtain their spectrum. In order to correct the positioning error of these optical fibers, the CCD camera is used to detect these fibers’ position in the way of close-range photogrammetry. As we all know, the calibration quality of the CCD camera is one of the most important factors for detection precision. However, the camera calibration has two following problems in the field work of LAMOST. First, the camera parameters are not stable due to the changes of on-site work environment and the vibration during movement. So, the CCD camera must be on-line calibrated. Second, a large-size high-precision calibration target is needed to calibrate the camera, for the focal plane is very big. Making such a calibration target, it is very difficult and costly. Meanwhile, the large calibration target is hard to be fixed on LAMOST because of the space constraint. In this paper, an improved bundle adjustment self-calibration method is proposed to solve the two problems above. The results of experiment indicate that this novel calibration method needs only a few control points while the traditional calibration methods need much more control points to get the same accuracy. So the method could realize the on-line high-precision calibration of CCD camera for LAMOST.

  18. Recent Advances in Imaging of Small and Large Bowel.

    PubMed

    Das, Chandan J; Manchanda, Smita; Panda, Ananya; Sharma, Anshul; Gupta, Arun K

    2016-01-01

    The diagnosis of bowel pathology is challenging in view of the nonspecific clinical presentation. Currently, there are various imaging modalities available to reach an accurate diagnosis. These modalities include conventional techniques (radiographs, small bowel follow-through, conventional enteroclysis), ultrasonography, and cross-sectional examinations (computed tomography [CT] and MR imaging) as well as functional imaging modalities, such as PET-CT or PET-MR imaging. Each modality has its own advantages and disadvantages and can be used in isolation or combination. This review discusses the role of CT, MR imaging, and PET-CT in the evaluation of small and large bowel diseases. PMID:26590441

  19. Advances in Imaging of the Pediatric Pituitary Gland.

    PubMed

    Bou-Ayache, Jad M; Delman, Bradley N

    2016-06-01

    High-resolution MRI of the pediatric sella can help identity or confirm clinical abnormalities, assess pituitary gland size and structure, and reveal acquired lesions. This article reviews contemporary techniques for imaging of the sella and associated structures in this population. Strengths and weaknesses of conventional imaging are discussed, as are techniques that can enhance yield. Some new and emerging technologies are discussed, including MR elastography, perfusion imaging, spectroscopy, and diffusion-weighted and diffusion-tensor imaging. It is expected that this overview will provide insight as to where pediatric sella imaging is currently and where it may head in the future. PMID:27241974

  20. Radiation load to the SNAP CCD

    SciTech Connect

    N. V. Mokhov, I. L. Rakhno and S. I. Striganov

    2003-08-14

    Results of an express Monte Carlo analysis with the MARS14 code of radiation load to the CCD optical detectors in the Supernova Acceleration Project (SNAP) mission presented for realistic radiation environment over the satellite orbit.

  1. The advancing clinical impact of molecular imaging in CVD.

    PubMed

    Osborn, Eric A; Jaffer, Farouc A

    2013-12-01

    Molecular imaging seeks to unravel critical molecular and cellular events in living subjects by providing complementary biological information to current structural clinical imaging modalities. In recent years, molecular imaging efforts have marched forward into the clinical cardiovascular arena, and are now actively illuminating new biology in a broad range of conditions, including atherosclerosis, myocardial infarction, thrombosis, vasculitis, aneurysm, cardiomyopathy, and valvular disease. Development of novel molecular imaging reporters is occurring for many clinical cardiovascular imaging modalities (positron emission tomography, single-photon emission computed tomography, magnetic resonance imaging), as well as in translational platforms such as intravascular fluorescence imaging. The ability to image, track, and quantify molecular biomarkers in organs not routinely amenable to biopsy (e.g., the heart and vasculature) open new clinical opportunities to tailor therapeutics based on a cardiovascular disease molecular profile. In addition, molecular imaging is playing an increasing role in atherosclerosis drug development in phase II clinical trials. Here, we present state-of-the-art clinical cardiovascular molecular imaging strategies, and explore promising translational approaches positioned for clinical testing in the near term. PMID:24332285

  2. Design of 300 frames per second 16-port CCD video processing circuit

    NASA Astrophysics Data System (ADS)

    Yang, Shao-hua; Guo, Ming-an; Li, Bin-kang; Xia, Jing-tao; Wang, Qunshu

    2011-08-01

    It is hard to achieve the speed of hundreds frames per second in high resolution charge coupled device (CCD) cameras, because the pixels' charge must be read out one by one in serial mode, this cost a lot of time. The multiple-port CCD technology is a new efficiency way to realize high frame rate high resolution solid state imaging systems. The pixel charge is read out from a multiple-port CCD through several ports in parallel mode, witch decrease the reading time of the CCD. But it is hard for the multiple-port CCDs' video processing circuit design, and the real time high speed image data acquisition is also a knotty problem. A 16-port high frame rate CCD video processing circuit based on Complex Programmable Logic Device (CPLD) and VSP5010 has been developed around a specialized back illuminated, 512 x 512 pixels, 400fps (frames per second) frame transfer CCD sensor from Sarnoff Ltd. A CPLD is used to produce high precision sample clock and timing, and the high accurate CCD video voltage sample is achieved with Correlated Double Sampling (CDS) technology. 8 chips of VSP5010 with CDS function is adopted to achieve sample and digitize CCD analog signal into 12 bit digital image data. Thus the 16 analog CCD output was digitized into 192 bit 6.67MHz parallel digital image data. Then CPLD and Time Division Multiplexing (TDM) technology are used to encode the 192 bit wide data into two 640MHz serial data and transmitted to remote data acquisition module via two fibers. The acquisition module decodes the serial data into original image data and stores the data into a frame cache, and then the software reads the data from the frame cache based on USB2.0 technology and stores the data in a hard disk. The digital image data with 12bit per pixel was collected and displayed with system software. The results show that the 16-por 300fps CCD output signals could be digitized and transmitted with the video processing circuit, and the remote data acquisition has been realized.

  3. New trends in developments of CCD arrays

    NASA Astrophysics Data System (ADS)

    Timofeev, V. O.

    2005-06-01

    Currently the number of foreign companies manufacturing the charge-coupled devices (CCD) comes to many tens, and manufacture of CCDs for different applications exceeds 10 million pieces per year. With the purpose to provide competition ability of our CCDs our enterprise has concentrated efforts on the manufacture of customized CCDs designed either for military or civilian applications. The main trends in the CCD developments are presented.

  4. Recent Advances in Image Assisted Neurosurgical Procedures: Improved Navigational Accuracy and Patient Safety

    ScienceCinema

    Olivi, Alessandro, M.D.

    2010-09-01

    Neurosurgical procedures require precise planning and intraoperative support. Recent advances in image guided technology have provided neurosurgeons with improved navigational support for more effective and safer procedures. A number of exemplary cases will be presented.

  5. Recent Advances in Image Assisted Neurosurgical Procedures: Improved Navigational Accuracy and Patient Safety

    SciTech Connect

    Olivi, Alessandro, M.D.

    2010-08-28

    Neurosurgical procedures require precise planning and intraoperative support. Recent advances in image guided technology have provided neurosurgeons with improved navigational support for more effective and safer procedures. A number of exemplary cases will be presented.

  6. Carbon nanotubes for biomedical imaging: the recent advances.

    PubMed

    Gong, Hua; Peng, Rui; Liu, Zhuang

    2013-12-01

    This article reviews the latest progresses regarding the applications of carbon nanotubes (CNTs), including single-walled carbon nanotubes (SWNTs) and multi-walled carbon nanotubes (MWNTs), as multifunctional nano-probes for biomedical imaging. Utilizing the intrinsic band-gap fluorescence of semi-conducting single-walled carbon nanotubes (SWNTs), fluorescence imaging in the near infrared II (NIR-II) region with enhanced tissue penetration and spatial resolution has shown great promise in recent years. Raman imaging based on the resonance Raman scattering of SWNTs has also been explored by a number of groups for in vitro and in vivo imaging of biological samples. The strong absorbance of CNTs in the NIR region can be used for photoacoustic imaging, and their photoacoustic signals can be dramatically enhanced by adding organic dyes, or coating with gold shells. Taking advantages of metal nanoparticle impurities attached to nanotubes, CNTs can also serve as a T2-contrast agent in magnetic resonance (MR) imaging. In addition, when labeled with radioactive isotopes, many groups have developed nuclear imaging with functionalized CNTs. Therefore CNTs are unique imaging probes with great potential in biomedical multimodal imaging. PMID:24184130

  7. The Advancing Clinical Impact of Molecular Imaging in Cardiovascular Disease

    PubMed Central

    Osborn, Eric A; Jaffer, Farouc A

    2013-01-01

    Molecular imaging seeks to unravel critical molecular and cellular events in living subjects by providing complementary biological information to current structural clinical imaging modalities. In recent years, molecular imaging efforts have marched forward into the clinical cardiovascular arena, and are now actively illuminating new biology in a broad range of conditions, including atherosclerosis, myocardial infarction, thrombosis, vasculitis, aneurysm, cardiomyopathy, and valvular disease. Development of novel molecular imaging reporters is occurring for many clinical cardiovascular imaging modalities (PET, SPECT, MRI), as well in translational platforms such as intravascular fluorescence imaging. The ability to image, track, and quantify molecular biomarkers in organs not routinely amenable to biopsy (e.g. the heart and vasculature) open new clinical opportunities to tailor therapeutics based on a cardiovascular disease molecular profile. In addition, molecular imaging is playing an increasing role in atherosclerosis drug development in Phase II clinical trials. Here we present state-of-the-art clinical cardiovascular molecular imaging strategies, and explore promising translational approaches positioned for clinical testing in the near term. PMID:24332285

  8. Advances in passive imaging elements with micromirror array

    NASA Astrophysics Data System (ADS)

    Maekawa, Satoshi; Nitta, Kouichi; Matoba, Osamu

    2008-02-01

    We have proposed a new passive imaging optics which consists of a grid array of micro roof mirrors working as dihedral corner reflectors. Although this element forms mirror-like images at opposite side of objects, the images are real. Because the imaging principle of the proposed element is based on accumulation of rays, the design of each light path makes many kinds of devices possible. So, we propose two variations of such a device. One device consists of an array of micro retroreflectors and a half mirror, and it can also form real mirror-like images. The advantage of this device is wide range of view, because the displacement of each retororeflector is not limited on a plane unlike the roof mirror grid array. The other consists of an array of long dihedral corner reflectors. Although this structure has been already known as a roof mirror array, it can be used for imaging. This device forms two heterogeneous images. One is real at the same side of an object, and the other is virtual at the opposite side. This is a conjugate imaging optics of a slit mirror array whose mirror surface is perpendicular to the device surface. The advantage of a roor mirror array is that the real image has horizontal parallax and can be seen in air naturally.

  9. Easily Transported CCD Systems for Use in Astronomy Labs

    NASA Astrophysics Data System (ADS)

    Meisel, D.

    1992-12-01

    Relatively inexpensive CCD cameras and portable computers are now easily obtained as commercially available products. I will describe a prototype system that can be used by introductory astronomy students, even urban enviroments, to obtain useful observations of the night sky. It is based on the ST-4 CCDs made by Santa Barbara Instruments Group and Macintosh Powerbook145 computers. Students take outdoor images directly from the college campus, bring the exposures back into the lab and download the images into our networked server. These stored images can then be processed (at a later time) using a variety of image processing programs including a new astronomical version of the popular "freeware" NIH Image package that is currently under development at Geneseo. The prototype of this system will be demonstrated and available for hands-on use during the meeting. This work is supported by NSF ILI Demonstration Grant USE9250493 and Grants from SUNY-GENESEO.

  10. MO-C-BRE-01: The WMIS-AAPM Joint Symposium: Advances in Molecular Imaging

    SciTech Connect

    Contag, C; Pogue, B; Lewis, J

    2014-06-15

    This joint symposium of the World Molecular Imaging Society (WMIS) and the AAPM includes three luminary speakers discussing work in new paradigms of molecular imaging in cancer (Contag), applications of optical imaging technologies to radiation therapy (Pogue) and an update on PET imaging as a surrogate biomarker for cancer progression and response to therapy. Learning Objectives: Appreciate the current trends in molecular and systems imaging. Understand how optical imaging technologies, and particularly Cerenkov detectors, can be used in advancing radiation oncology. Stay current on new PET tracers - and targets - of interest in cancer treatment.

  11. Advanced fiber optic face plate quality detector design

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Su, Liping; Zhao, Jingxia

    2010-10-01

    A fiber optic face plate is defined by a plurality of fibers of transparent material that are fused and compressed together to transmit an image from one end to another end. Fiber optic face plates exhibit utility in the image intensifiers, cathoderay tubes, and other media displays. In this paper, the design of an advanced fiber optic face plate quality detector is presented. Modern optoelectronic imaging techniques are being used to form fiber optic plate transmission images that are suitable for analyzing the quality parameters of fiber optic face plate. The diffusing light from a halogen lamp is condensed by condenser lens then through a fiber optic face plate, a set of lenses are used to magnify the transmission image, a computer controls a long linear CCD to scan the transmission image, a data grabber captures the CCD's output data and the computer transforms the data into frame image for further analysis. Digital image processing techniques are adopted to analyze the transmission image to obtain the required quality parameters. The image analysis software combines the API that a company provided and programed API is used to acquire the quality parameter that a relevant criteria required. With the long linear CCD scanning and image analysis being computerized, it accomplishes the detection of quality parameters of fiber optic face plates automaticly. The detector can replace the manual detection method and can be widely used for the quality detection of fiber optic face plate. Manufacturers of fiber optic face plates can benefit from the detector for quality control.

  12. Speckle-based modulation transfer function measurements for comparative evaluation of CCD and CMOS detector arrays

    NASA Astrophysics Data System (ADS)

    Fernández-Oliveras, Alicia; Pozo, Antonio M.; Rubiño, Manuel

    2013-01-01

    Charge-coupled device (CCD) and complementary metal-oxide semiconductor (CMOS) matrices offer excellent features in imaging systems. For assessing the suitability of each technology according to the application, the complete characterization of the detector arrays becomes necessary. A system is optically characterized by the modulation transfer function (MTF). We have comparatively studied the results provided by the speckle method for detectors of two types: CCD and CMOS. To do so, we first analysed the precision in determining the MTF of the CCD using two apertures at the exit port of an integrating sphere: a single and a double-slit. For the single-slit, we propose a new procedure of fitting the experimental data which overcomes the drawbacks of the conventional procedure. Since it offered lower uncertainty and better reproducibility, the single-slit was used for the study with the CMOS detector. Significant differences were found between the MTF of the CCD and the CMOS detectors.

  13. First results with the pn-CCD detector system for the XMM satellite mission

    NASA Astrophysics Data System (ADS)

    Bräuninger, H.; Danner, R.; Hauff, D.; Lechner, P.; Lutz, G.; Meidinger, N.; Pinotti, E.; Reppin, C.; Strüder, L.; Trümper, J.; Kendziorra, E.; Krämer, J.; Mohan, M.; Staubert, R.; Findeis, N.; Holl, P.; Kemmer, J.; von Zanthier, C.

    1993-03-01

    The pn-CCD is a novel CCD type which is developed for fast X-ray imaging and spectroscopy for the X-ray Multi Mirror (XMM) satellite mission. Each 200 × 64 pixel large pn-CCD unit with a sensitive area of 3 × 1 cm 2 is a fully depleted detector. Full depletion allows for high photon detection efficiency (> 90% in the energy range of 500 eV-10 keV), for a small input capacitance necessary for low noise signal measurements and for backward illumination. For good time resolution and low noise performance each of the 64 CCD channels is terminated with an integrated input-JFET for signal amplification. With the use of the CMOS Amplifier and Multiplexing Chip (CAMEX64B) it is possible to read out the 64 CCD channels in parallel before they are multiplexed and sent to an ADC. For the first time the system of a 64 channel pn-CCD together with CAMEX64B readout, ADC conversion and data acquisition and storage has been brought into operation. First images of an 55Fe X-ray source are presented and discussed.

  14. Advances in multimodality molecular imaging of bone structure and function

    PubMed Central

    Lambers, Floor M; Kuhn, Gisela; Müller, Ralph

    2012-01-01

    The skeleton is important to the body as a source of minerals and blood cells and provides a structural framework for strength, mobility and the protection of organs. Bone diseases and disorders can have deteriorating effects on the skeleton, but the biological processes underlying anatomical changes in bone diseases occurring in vivo are not well understood, mostly due to the lack of appropriate analysis techniques. Therefore, there is ongoing research in the development of novel in vivo imaging techniques and molecular markers that might help to gain more knowledge of these pathological pathways in animal models and patients. This perspective provides an overview of the latest developments in molecular imaging applied to bone. It emphasizes that multimodality imaging, the combination of multiple imaging techniques encompassing different image modalities, enhances the interpretability of data, and is imperative for the understanding of the biological processes and the associated changes in bone structure and function relationships in vivo. PMID:27127622

  15. PIFEX: An advanced programmable pipelined-image processor

    NASA Technical Reports Server (NTRS)

    Gennery, D. B.; Wilcox, B.

    1985-01-01

    PIFEX is a pipelined-image processor being built in the JPL Robotics Lab. It will operate on digitized raster-scanned images (at 60 frames per second for images up to about 300 by 400 and at lesser rates for larger images), performing a variety of operations simultaneously under program control. It thus is a powerful, flexible tool for image processing and low-level computer vision. It also has applications in other two-dimensional problems such as route planning for obstacle avoidance and the numerical solution of two-dimensional partial differential equations (although its low numerical precision limits its use in the latter field). The concept and design of PIFEX are described herein, and some examples of its use are given.

  16. The Crimean CCD Telescope for the asteroid observations

    NASA Astrophysics Data System (ADS)

    Chernykh, N. S.; Rumyantsev, V. V.

    2002-09-01

    The old 64-cm Richter-Slefogt telescope (F=90 cm) of the Crimean Astrophysical Observatory was reconstructed and equipped with the SBIG ST-8 CCD camera received from the Planetary Society for Eugene Shoemaker's Near Earth Object Grant. First observations of minor planets and comets were made with it. The CCD matrix of the St-8 camera in the focus of our telescope covers a field of 52'.7 x 35'.1. The 120 - second exposure yields stars up to the limiting magnitude of 20.5 for S/N=3. According to preliminary estimations, the telescope of today state enables us to cover, during the year, the sky area of not more than 600 sq. deg. with threefold overlaps. An automation of the telescope can increase the productivity up to 20000 sq. deg. per year. The software for object localization, image parameters determination, stars identification, astrometric reduction, identification and catalogue of asteroids is worked up. The first results obtained with the Crimean CCD 64-cm telescope are discussed.

  17. Correcting STIS CCD Point-Source Spectra for CTE Loss

    NASA Technical Reports Server (NTRS)

    Goudfrooij, Paul; Bohlin, Ralph C.; Maiz-Apellaniz, Jesus

    2006-01-01

    We review the on-orbit spectroscopic observations that are being used to characterize the Charge Transfer Efficiency (CTE) of the STIS CCD in spectroscopic mode. We parameterize the CTE-related loss for spectrophotometry of point sources in terms of dependencies on the brightness of the source, the background level, the signal in the PSF outside the standard extraction box, and the time of observation. Primary constraints on our correction algorithm are provided by measurements of the CTE loss rates for simulated spectra (images of a tungsten lamp taken through slits oriented along the dispersion axis) combined with estimates of CTE losses for actual spectra of spectrophotometric standard stars in the first order CCD modes. For point-source spectra at the standard reference position at the CCD center, CTE losses as large as 30% are corrected to within approx.1% RMS after application of the algorithm presented here, rendering the Poisson noise associated with the source detection itself to be the dominant contributor to the total flux calibration uncertainty.

  18. Using a Web Cam CCD to do V Band Photometry

    NASA Astrophysics Data System (ADS)

    Temple, Paul

    2009-05-01

    With the plethora of cheap web cam based CCD cameras in the market today, it seemed expedient to find out if they can be used to do photometry. An experiment was planned to determine if it was possible to do this kind of exacting measurement. Arne Henden (AAVSO) believed it would be possible to do V band photometry to 0.05 mag accuracy with a web cam CCD. Using a 6" refractor, the heart of M42 was repeatedly imaged. Theta 2 and SAO 132322 were the comparison stars and V361 Orion was the target variable. Since the 1/4 HAD CCD chip only allows for a field of 10x7 arc minutes using the 6" refractor, the number targets was limited. The RGB on the chip itself provides the filters needed for photometry. The G band pass on the chip ranges from 425-650 nm with a peak band pass at 540, V band pass is 475-645 with a peak at 525. The results indicate that a web cam CCD can be used for V band photometry. With a 10 second calibrated exposure without the Peltier cooling being engaged, the results for the 2 target stars were ± 0.18 mag. The star Theta 2 was 0.18 brighter in V than the actual measurement from the Tycho catalog. SAO 132322 was -0.012 mag dimmer than the listed Tycho measurement. Then using SAO 132322 and Theta 2 as comparison stars, V361 Orion was estimated at 7.786 magnitudes. This is inline with visual estimates received before and after this date. With more estimates of known magnitude comparison stars, a correction factor should be estimated and applied to the variable work that will make it more accurate. This correction factor should bring it close to Arne Henden's estimate of 0.05 mag accuracy.

  19. Fully depleted back-illuminated p-channel CCD development

    SciTech Connect

    Bebek, Chris J.; Bercovitz, John H.; Groom, Donald E.; Holland, Stephen E.; Kadel, Richard W.; Karcher, Armin; Kolbe, William F.; Oluseyi, Hakeem M.; Palaio, Nicholas P.; Prasad, Val; Turko, Bojan T.; Wang, Guobin

    2003-07-08

    An overview of CCD development efforts at Lawrence Berkeley National Laboratory is presented. Operation of fully-depleted, back-illuminated CCD's fabricated on high resistivity silicon is described, along with results on the use of such CCD's at ground-based observatories. Radiation damage and point-spread function measurements are described, as well as discussion of CCD fabrication technologies.

  20. 3D Imaging with Structured Illumination for Advanced Security Applications

    SciTech Connect

    Birch, Gabriel Carisle; Dagel, Amber Lynn; Kast, Brian A.; Smith, Collin S.

    2015-09-01

    Three-dimensional (3D) information in a physical security system is a highly useful dis- criminator. The two-dimensional data from an imaging systems fails to provide target dis- tance and three-dimensional motion vector, which can be used to reduce nuisance alarm rates and increase system effectiveness. However, 3D imaging devices designed primarily for use in physical security systems are uncommon. This report discusses an architecture favorable to physical security systems; an inexpensive snapshot 3D imaging system utilizing a simple illumination system. The method of acquiring 3D data, tests to understand illumination de- sign, and software modifications possible to maximize information gathering capability are discussed.