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Sample records for advanced cell technology

  1. Advanced Cell Technology, Inc.

    PubMed

    Caldwell, William M

    2007-03-01

    Advanced Cell Technology, Inc. (OTCBB: ACTC) is a biotechnology company applying novel human embryonic stem cell technologies in the emerging field of regenerative medicine. We believe that regenerative medicine has the potential to revolutionize the field by enabling scientists to produce human cells of any kind for use in a wide array of therapies.

  2. Technology Advancement for Integrative Stem Cell Analyses

    PubMed Central

    Jeong, Yoon

    2014-01-01

    Scientists have endeavored to use stem cells for a variety of applications ranging from basic science research to translational medicine. Population-based characterization of such stem cells, while providing an important foundation to further development, often disregard the heterogeneity inherent among individual constituents within a given population. The population-based analysis and characterization of stem cells and the problems associated with such a blanket approach only underscore the need for the development of new analytical technology. In this article, we review current stem cell analytical technologies, along with the advantages and disadvantages of each, followed by applications of these technologies in the field of stem cells. Furthermore, while recent advances in micro/nano technology have led to a growth in the stem cell analytical field, underlying architectural concepts allow only for a vertical analytical approach, in which different desirable parameters are obtained from multiple individual experiments and there are many technical challenges that limit vertically integrated analytical tools. Therefore, we propose—by introducing a concept of vertical and horizontal approach—that there is the need of adequate methods to the integration of information, such that multiple descriptive parameters from a stem cell can be obtained from a single experiment. PMID:24874188

  3. Technology advancement for integrative stem cell analyses.

    PubMed

    Jeong, Yoon; Choi, Jonghoon; Lee, Kwan Hyi

    2014-12-01

    Scientists have endeavored to use stem cells for a variety of applications ranging from basic science research to translational medicine. Population-based characterization of such stem cells, while providing an important foundation to further development, often disregard the heterogeneity inherent among individual constituents within a given population. The population-based analysis and characterization of stem cells and the problems associated with such a blanket approach only underscore the need for the development of new analytical technology. In this article, we review current stem cell analytical technologies, along with the advantages and disadvantages of each, followed by applications of these technologies in the field of stem cells. Furthermore, while recent advances in micro/nano technology have led to a growth in the stem cell analytical field, underlying architectural concepts allow only for a vertical analytical approach, in which different desirable parameters are obtained from multiple individual experiments and there are many technical challenges that limit vertically integrated analytical tools. Therefore, we propose--by introducing a concept of vertical and horizontal approach--that there is the need of adequate methods to the integration of information, such that multiple descriptive parameters from a stem cell can be obtained from a single experiment.

  4. Recent Advances in Solar Cell Technology

    NASA Technical Reports Server (NTRS)

    Landis, Geoffrey A.; Bailey, Sheila G.; Piszczor, Michael F., Jr.

    1996-01-01

    The advances in solar cell efficiency, radiation tolerance, and cost over the last decade are reviewed. Potential performance of thin-film solar cells in space are discussed, and the cost and the historical trends in production capability of the photovoltaics industry are considered with respect to the requirements of space power systems. Concentrator cells with conversion efficiency over 30%, and nonconcentrating solar cells with efficiency over 25% are now available, and advanced radiation-tolerant cells and lightweight, thin-film arrays are both being developed. Nonsolar applications of solar cells, including thermophotovoltaics, alpha- and betavoltaics, and laser power receivers, are also discussed.

  5. Process Technology and Advanced Concepts: Organic Solar Cells (Fact Sheet)

    SciTech Connect

    Not Available

    2011-06-01

    Capabilities fact sheet for the National Center for Photovoltaics: Process Technology and Advanced Concepts: Organic Solar Cell that includes scope, core competencies and capabilities, and contact/web information.

  6. Recent technological advances in thin film solar cells

    SciTech Connect

    Ullal, H.S.; Zwelbel, K.; Surek, T.

    1990-03-01

    High-efficiency, low-cost thin film solar cells are an exciting photovoltaic technology option for generating cost-effective electricity in 1995 and beyond. This paper reviews the substantial advances made by several thin film solar cell technologies, namely, amorphous silicon, copper indium diselenide, cadmium telluride, and polycrystalline silicon. Recent examples of utility demonstration projects of these emerging materials are also discussed. 8 refs., 4 figs.

  7. Advanced technology lightweight fuel cell program

    NASA Technical Reports Server (NTRS)

    Martin, R. E.

    1981-01-01

    The potential of the alkaline electrolyte fuel cell as the power source in a multi hundred kilowatt orbital energy storage system was studied. The total system weight of an electrolysis cell energy storage system was determined. The tests demonstrated: (1) the performance stability of a platinum on carbon anode catalyst configuration after 5000 hours of testing has no loss in performance; (2) capability of the alkaline fuel cell to operate to a cyclical load profile; (3) suitability of a lightweight graphite electrolyte reservoir plate for use in the alkaline fuel cell; (4) long life potential of a hybrid polysulfone cell edge frame construction; and (5) long term stability of a fiber reinforced potassium titanate matrix structure. The power section tested operates with passive water removal eliminating the requirement for a dynamic hydrogen pump water separator thereby allowing a powerplant design with reduced weight, lower parasite power, and a potential for high reliability and extended endurance. It is concluded that two perovskites are unsuitable for use as a catalyst or as a catalyst support at the cathode of an alkaline fuel cell.

  8. Recent advances in cell sheet technology for periodontal regeneration.

    PubMed

    Wang, Jing; Zhang, Rui; Shen, Yun; Xu, Chenyuan; Qi, Shengcai; Lu, Liyan; Wang, Raorao; Xu, Yuanzhi

    2014-05-01

    Tissue engineering has yielded several successes in early clinical trials of regenerative medicine with grafting therapeutic cells seeded into biodegradable scaffolds. However this conventional cell delivery method has limited the field's progress. In recent decades, we have developed a novel cell transferring method, cell sheet technology that allows for controlled attachment and detachment of cells via simple temperature variations of a surface-intelligent temperatureresponsive polymer:poly (N-isopropylacrylamide). It has been widely applied to create functional tissue sheets with cells derived from various tissues to treat a wide range of diseases. Periodontal cell sheets non-invasively harvested from temperature- responsive culture surfaces have been successfully manufactured, resulting in communicative multilayered constructs. Transplantation of cell sheets onto periodontal defects has improved bone and tissue regeneration in animal models and humans and shows low immunogenicity. In this review, we summarize the recent advances of techniques in cell sheet engineering and its application for periodontal regeneration.

  9. Technological advances in real-time tracking of cell death

    PubMed Central

    Skommer, Joanna; Darzynkiewicz, Zbigniew; Wlodkowic, Donald

    2010-01-01

    Cell population can be viewed as a quantum system, which like Schrödinger’s cat exists as a combination of survival- and death-allowing states. Tracking and understanding cell-to-cell variability in processes of high spatio-temporal complexity such as cell death is at the core of current systems biology approaches. As probabilistic modeling tools attempt to impute information inaccessible by current experimental approaches, advances in technologies for single-cell imaging and omics (proteomics, genomics, metabolomics) should go hand in hand with the computational efforts. Over the last few years we have made exciting technological advances that allow studies of cell death dynamically in real-time and with the unprecedented accuracy. These approaches are based on innovative fluorescent assays and recombinant proteins, bioelectrical properties of cells, and more recently also on state-of-the-art optical spectroscopy. Here, we review current status of the most innovative analytical technologies for dynamic tracking of cell death, and address the interdisciplinary promises and future challenges of these methods. PMID:20519963

  10. Recent advances in solid polymer electrolyte fuel cell technology

    SciTech Connect

    Ticianelli, E.A.; Srinivasan, S.; Gonzalez, E.R.

    1988-01-01

    With methods used to advance solid polymer electrolyte fuel cell technology, we are close to obtaining the goal of 1 A/cm/sup 2/ at 0.7. Higher power densities have been reported (2 A/cm/sup 2/ at 0.5 V) but only with high catalyst loading electrodes (2 mg/cm/sup 2/ and 4 mg/cm/sup 2/ at anode and cathode, respectively) and using a Dow membrane with a better conductivity and water retention characteristics. Work is in progress to ascertain performances of cells with Dow membrane impregnated electrodes and Dow membrane electrolytes. 5 refs., 6 figs.

  11. Advances in Li-TiS2 cell technology

    NASA Technical Reports Server (NTRS)

    Surampudi, S.; Shen, D. H.; Huang, C.-K.; Deligiannis, F.; Attia, A. I.; Halpert, G.

    1991-01-01

    Jet Propulsion Laboratories (JPL) is involved in a NASA sponsored program to develop ambient temperature secondary cells for future space missions. After several years of research on various cathode materials, titanium disulfide (TiS2) was selected in view of its intrinsic reversibility and high faradaic utilization. In the last two years, the efforts were focussed on improving the cycle life of the system and developing 1 Ah cells. Several approaches including the use of mixed solvent electrolytes, the operation of cells at low temperature, and the cycling of cells under different voltage limits, were initially examined to improve the cycle life performance of the Li/TiS2 system. Spiral wound 1 Ah cells fabricated incorporating the improvements from the above studies have delivered more than 600 cycles at 50 percent depth of discharge (DOD). Work is in progress to identify alternate anode materials that can improve the cycle life of the cells to 1000 cycles at 50 percent DOD. The advances made in the Li/TiS2 technology at JPL since 1989 are summarized.

  12. Advances in Li-TiS2 cell technology

    NASA Astrophysics Data System (ADS)

    Surampudi, S.; Shen, D. H.; Huang, C.-K.; Deligiannis, F.; Attia, A. I.; Halpert, G.

    1991-09-01

    Jet Propulsion Laboratories (JPL) is involved in a NASA sponsored program to develop ambient temperature secondary cells for future space missions. After several years of research on various cathode materials, titanium disulfide (TiS2) was selected in view of its intrinsic reversibility and high faradaic utilization. In the last two years, the efforts were focussed on improving the cycle life of the system and developing 1 Ah cells. Several approaches including the use of mixed solvent electrolytes, the operation of cells at low temperature, and the cycling of cells under different voltage limits, were initially examined to improve the cycle life performance of the Li/TiS2 system. Spiral wound 1 Ah cells fabricated incorporating the improvements from the above studies have delivered more than 600 cycles at 50 percent depth of discharge (DOD). Work is in progress to identify alternate anode materials that can improve the cycle life of the cells to 1000 cycles at 50 percent DOD. The advances made in the Li/TiS2 technology at JPL since 1989 are summarized.

  13. Technological Advancements

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2010-01-01

    The influx of technology has brought significant improvements to school facilities. Many of those advancements can be found in classrooms, but when students head down the hall to use the washrooms, they are likely to find a host of technological innovations that have improved conditions in that part of the building. This article describes modern…

  14. Advances and Applications of Single Cell Sequencing Technologies

    PubMed Central

    Wang, Yong; Navin, Nicholas E.

    2015-01-01

    Single cell sequencing (SCS) has emerged as a powerful new set of technologies for studying rare cells and delineating complex populations. Over the past 5 years, SCS methods for DNA and RNA have had a broad impact on many diverse fields of biology, including microbiology, neurobiology, development, tissue mosaicism, immunology and cancer research. In this review, we will discuss SCS technologies and applications, as well as translational applications in the clinic. PMID:26000845

  15. Recent advances in microbial single cell genomics technology and applications

    NASA Astrophysics Data System (ADS)

    Stepanauskas, R.

    2015-12-01

    Single cell genomics is increasingly utilized as a powerful tool to decipher the metabolic potential, evolutionary histories and in situ interactions of environmental microorganisms. I will present several new developments of this exciting technology, which improve genomic data recovery from individual cells and allow its integration with cell's phenotypic properties. I will also demonstrate how these new technical capabilities help understanding the biology of the "microbial dark matter" inhabiting marine and terrestrial subsurface environments.

  16. Advanced technology for extended endurance alkaline fuel cells

    NASA Technical Reports Server (NTRS)

    Sheibley, D. W.; Martin, R. A.

    1987-01-01

    Advanced components have been developed for alkaline fuel cells with a view to the satisfaction of NASA Space Station design requirements for extended endurance. The components include a platinum-on-carbon catalyst anode, a potassium titanate-bonded electrolyte matrix, a lightweight graphite electrolyte reservoir plate, a gold-plated nickel-perforated foil electrode substrate, a polyphenylene sulfide cell edge frame material, and a nonmagnesium cooler concept. When incorporated into the alkaline fuel cell unit, these components are expected to yield regenerative operation in a low earth orbit Space Station with a design life greater than 5 years.

  17. Advances in tubular solid oxide fuel cell technology

    SciTech Connect

    Singhal, S.C.

    1996-12-31

    The design, materials and fabrication processes for the earlier technology Westinghouse tubular geometry cell have been described in detail previously. In that design, the active cell components were deposited in the form of thin layers on a ceramic porous support tube (PST). The tubular design of these cells and the materials used therein have been validated by successful electrical testing for over 65,000 h (>7 years). In these early technology PST cells, the support tube, although sufficiently porous, presented an inherent impedance to air flow toward air electrode. In order to reduce such impedance to air flow, the wall thickness of the PST was first decreased from the original 2 mm (the thick-wall PST) to 1.2 mm (the thin-wall PST). The calcia-stabilized zirconia support tube has now been completely eliminated and replaced by a doped lanthanum manganite tube in state-of-the-art SOFCs. This doped lanthanum manganite tube is extruded and sintered to about 30 to 35 percent porosity, and serves as the air electrode onto which the other cell components are fabricated in thin layer form. These latest technology cells are designated as air electrode supported (AES) cells.

  18. [Technological advances in single-cell genomic analyses].

    PubMed

    Pan, Xing-Hua; Zhu, Hai-Ying; Marjani, Sadie L

    2011-01-01

    The technological progress of the genomics has transformed life science research. The main objectives of genomics are sequencing of new genomes and genome-wide identification of the function and the interaction of genes and their products. The recently developed second generation or next generation sequencing platforms and DNA microarray technology are immensely important and powerful tools for functional genomic analyses. However, their application is limited by the requirement of sufficient amounts of high quality nucleic acid samples. Therefore, when only a single cell or a very small number of cells are available or are preferred, the whole genomic sequencing or functional genomic objectives cannot be achieved conventionally and require a robust amplification method. This review highlights DNA amplification technologies and summarizes the strategies currently utilized for whole genome sequencing of a single cell, with specific focus on studies investigating microorganisms; An outline for targeted re-sequencing enabling the analysis of larger genomes is also provided. Furthermore, the review presents the emerging functional genomic applications using next-generation sequencing or microarray analysis to examine genome-wide transcriptional profile, chromatin modification and other types of protein-DNA binding profile, and CpG methylation mapping in a single cell or a very low quantity of cells. The nature of these technologies and their prospects are also addressed.

  19. Cell death goes LIVE: technological advances in real-time tracking of cell death.

    PubMed

    Skommer, Joanna; Darzynkiewicz, Zbigniew; Wlodkowic, Donald

    2010-06-15

    Cell population can be viewed as a quantum system, which like Schrödinger's cat exists as a combination of survival- and death-allowing states. Tracking and understanding cell-to-cell variability in processes of high spatio-temporal complexity such as cell death is at the core of current systems biology approaches. As probabilistic modeling tools attempt to impute information inaccessible by current experimental approaches, advances in technologies for single-cell imaging and omics (proteomics, genomics, metabolomics) should go hand in hand with the computational efforts. Over the last few years we have made exciting technological advances that allow studies of cell death dynamically in real-time and with the unprecedented accuracy. These approaches are based on innovative fluorescent assays and recombinant proteins, bioelectrical properties of cells, and more recently also on state-of-the-art optical spectroscopy. Here, we review current status of the most innovative analytical technologies for dynamic tracking of cell death, and address the interdisciplinary promises and future challenges of these methods.

  20. Advances in Materials and System Technology for Portable Fuel Cells

    NASA Technical Reports Server (NTRS)

    Narayanan, Sekharipuram R.

    2007-01-01

    This viewgraph presentation describes the materials and systems engineering used for portable fuel cells. The contents include: 1) Portable Power; 2) Technology Solution; 3) Portable Hydrogen Systems; 4) Direct Methanol Fuel Cell; 5) Direct Methanol Fuel Cell System Concept; 6) Overview of DMFC R&D at JPL; 7) 300-Watt Portable Fuel Cell for Army Applications; 8) DMFC units from Smart Fuel Cell Inc, Germany; 9) DMFC Status and Prospects; 10) Challenges; 11) Rapid Screening of Well-Controlled Catalyst Compositions; 12) Screening of Ni-Zr-Pt-Ru alloys; 13) Issues with New Membranes; 14) Membranes With Reduced Methanol Crossover; 15) Stacks; 16) Hybrid DMFC System; 17) Small Compact Systems; 18) Durability; and 19) Stack and System Parameters for Various Applications.

  1. Electric utility acid fuel cell stack technology advancement

    NASA Technical Reports Server (NTRS)

    Congdon, J. V.; Goller, G. J.; Greising, G. J.; Obrien, J. J.; Randall, S. A.; Sandelli, G. J.; Breault, R. D.; Austin, G. W.; Bopse, S.; Coykendall, R. D.

    1984-01-01

    The principal effort under this program was directed at the fuel cell stack technology required to accomplish the initial feasibility demonstrations of increased cell stack operating pressures and temperatures, increased cell active area, incorporation of the ribbed substrate cell configuration at the bove conditions, and the introduction of higher performance electrocatalysts. The program results were successful with the primary accomplishments being: (1) fabrication of 10 sq ft ribbed substrate, cell components including higher performing electrocatalysts; (2) assembly of a 10 sq ft, 30-cell short stack; and (3) initial test of this stack at 120 psia and 405 F. These accomplishments demonstrate the feasibility of fabricating and handling large area cells using materials and processes that are oriented to low cost manufacture. An additional accomplishment under the program was the testing of two 3.7 sq ft short stacks at 12 psia/405 F to 5400 and 4500 hours respectively. These tests demonstrate the durability of the components and the cell stack configuration to a nominal 5000 hours at the higher pressure and temperature condition planned for the next electric utility power plant.

  2. Initial Comparisons between the Advanced Technology Development Gen 2 Baseline Cells and Variant C Cells

    SciTech Connect

    Christophersen, Jon Petter; Motloch, Chester George; Wright, Randy Ben; Murphy, Timothy Collins; Belt, Jeffrey R; Ho, Chinh Dac; Bloom, Ira D.; Jones, S. A.; Battaglia, Vincent S.; Jungst, Rudy G.; Case, Herb L.; Sutula, Raymond A.; Barnes, James A.; Duong, Tien Q.

    2002-06-01

    The Advanced Technology Development Program is testing a second generation of lithium-ion cells, consisting of a baseline and three variant chemistries. The cathode composition of the Variant C chemistry was altered with an increase to the aluminum dopant and a decrease to the cobalt dopant to explore the impact on performance. However, it resulted in a 20% drop in rated capacity. Also, the Variant C average power fade is higher, but capacity fade is higher for the Baseline cell chemistry. Initial results indicate that the Variant C chemistry will reach end of life sooner than the Baseline chemistry.

  3. Further advances in silicon solar cell technology for space application

    NASA Technical Reports Server (NTRS)

    Lillington, D. R.; Kukulka, J. R.

    1986-01-01

    Recent improvements relating to the design of high efficiency cells are presented. A conceptual design using passivation techniques is discussed, which potentially increases the open circuit voltage to approximately 650 mV. This concept is supported by experimental data using only silicon passivation beneath contacts. The use of thin thermal oxides of silicon for passivation between contacts is also discussed. A number of novel structures have also been fabricated to investigate reduction in the thermal alpha of planar and sculptured cells. It is shown that this may be as low as 0.63 on glassed gridded back cells, and that the IR rejection beyond 1.1 microns may approach 100 percent if the backside is AR coated. Finally, experimental data is given to support the existence of free electron absorption in heavily doped emitters on sculptured cells.

  4. Validation test of advanced technology for IPV nickel-hydrogen flight cells: Update

    NASA Astrophysics Data System (ADS)

    Smithrick, John J.; Hall, Stephen W.

    1992-05-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the low-earth-orbit (LEO) cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing at the Naval Weapons Support Center (NWSC), Crane, Indiana under a NASA Lewis Contract. An advanced 125 Ah IPV nickel-hydrogen cell was designed. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion. The advanced cell design is in the process of being validated using real time LEO cycle life testing of NWSC, Crane, Indiana. An update of validation test results confirming this technology is presented.

  5. Validation test of advanced technology for IPV nickel-hydrogen flight cells: Update

    NASA Technical Reports Server (NTRS)

    Smithrick, John J.; Hall, Stephen W.

    1992-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the low-earth-orbit (LEO) cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing at the Naval Weapons Support Center (NWSC), Crane, Indiana under a NASA Lewis Contract. An advanced 125 Ah IPV nickel-hydrogen cell was designed. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion. The advanced cell design is in the process of being validated using real time LEO cycle life testing of NWSC, Crane, Indiana. An update of validation test results confirming this technology is presented.

  6. Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

    PubMed Central

    Lai, Tingfeng; Yang, Yuansheng; Ng, Say Kong

    2013-01-01

    From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been approved by US Food and Drug Administration (FDA) annually. In addition, the expiration of blockbuster biologics has also spurred the emergence of biosimilars. The increasing numbers of innovator biologic products and biosimilars have thus fuelled the demand of production cell lines with high productivity. Currently, mammalian cell line development technologies used by most biopharmaceutical companies are based on either the methotrexate (MTX) amplification technology or the glutamine synthetase (GS) system. With both systems, the cell clones obtained are highly heterogeneous, as a result of random genome integration by the gene of interest and the gene amplification process. Consequently, large numbers of cell clones have to be screened to identify rare stable high producer cell clones. As such, the cell line development process typically requires 6 to 12 months and is a time, capital and labour intensive process. This article reviews established advances in protein expression and clone screening which are the core technologies in mammalian cell line development. Advancements in these component technologies are vital to improve the speed and efficiency of generating robust and highly productive cell line for large scale production of protein therapeutics. PMID:24276168

  7. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Fourth Results Report

    SciTech Connect

    Eudy, L.; Chandler, K.

    2013-01-01

    SunLine Transit Agency, which provides public transit services to the Coachella Valley area of California, has demonstrated hydrogen and fuel cell bus technologies for more than 10 years. In May 2010, SunLine began demonstrating the advanced technology (AT) fuel cell bus with a hybrid electric propulsion system, fuel cell power system, and lithium-based hybrid batteries. This report describes operations at SunLine for the AT fuel cell bus and five compressed natural gas buses. The U.S. Department of Energy's National Renewable Energy Laboratory (NREL) is working with SunLine to evaluate the bus in real-world service to document the results and help determine the progress toward technology readiness. NREL has previously published three reports documenting the operation of the fuel cell bus in service. This report provides a summary of the results with a focus on the bus operation from February 2012 through November 2012.

  8. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: First Results Report

    SciTech Connect

    Eudy, L.; Chandler, K.

    2011-03-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. This report provides the early data results and implementation experience of the AT fuel cell bus since it was placed in service.

  9. Systems biology of yeast: enabling technology for development of cell factories for production of advanced biofuels.

    PubMed

    de Jong, Bouke; Siewers, Verena; Nielsen, Jens

    2012-08-01

    Transportation fuels will gradually shift from oil based fuels towards alternative fuel resources like biofuels. Current bioethanol and biodiesel can, however, not cover the increasing demand for biofuels and there is therefore a need for advanced biofuels with superior fuel properties. Novel cell factories will provide a production platform for advanced biofuels. However, deep cellular understanding is required for improvement of current biofuel cell factories. Fast screening and analysis (-omics) methods and metabolome-wide mathematical models are promising techniques. An integrated systems approach of these techniques drives diversity and quantity of several new biofuel compounds. This review will cover the recent technological developments that support improvement of the advanced biofuels 1-butanol, biodiesels and jetfuels.

  10. Validation test of advanced technology for IPV nickel-hydrogen flight cells - Update

    NASA Astrophysics Data System (ADS)

    Smithrick, John J.; Hall, Stephen W.

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the LEO cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion.

  11. Validation test of advanced technology for IPV nickel-hydrogen flight cells - Update

    NASA Technical Reports Server (NTRS)

    Smithrick, John J.; Hall, Stephen W.

    1992-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the LEO cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion.

  12. Advanced Manufacturing Technologies

    NASA Technical Reports Server (NTRS)

    Fikes, John

    2016-01-01

    Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

  13. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Second Results Report and Appendices

    SciTech Connect

    Eudy, L.; Chandler, K.

    2011-10-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. This is the second results report for the AT fuel cell bus since it was placed in service, and it focuses on the newest data analysis and lessons learned since the previous report. The appendices, referenced in the main report, provide the full background for the evaluation. They will be updated as new information is collected but will contain the original background material from the first report.

  14. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Third Results Reports

    SciTech Connect

    Eudy, L.; Chandler, K.

    2012-05-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. NREL has previously published two reports documenting the operation of the fuel cell bus in service. This report provides a summary of the results with a focus on the bus operation from July 2011 through January 2012.

  15. Advanced sensors technology survey

    NASA Technical Reports Server (NTRS)

    Cooper, Tommy G.; Costello, David J.; Davis, Jerry G.; Horst, Richard L.; Lessard, Charles S.; Peel, H. Herbert; Tolliver, Robert

    1992-01-01

    This project assesses the state-of-the-art in advanced or 'smart' sensors technology for NASA Life Sciences research applications with an emphasis on those sensors with potential applications on the space station freedom (SSF). The objectives are: (1) to conduct literature reviews on relevant advanced sensor technology; (2) to interview various scientists and engineers in industry, academia, and government who are knowledgeable on this topic; (3) to provide viewpoints and opinions regarding the potential applications of this technology on the SSF; and (4) to provide summary charts of relevant technologies and centers where these technologies are being developed.

  16. Application of Pixel-cell Detector Technology for Advanced Neutron Beam Monitors

    SciTech Connect

    Kopp, Daniel M.

    2011-01-11

    Application of Pixel-Cell Detector Technology for Advanced Neutron Beam Monitors Specifications of currently available neutron beam detectors limit their usefulness at intense neutron beams of large-scale national user facilities used for the advanced study of materials. A large number of neutron-scattering experiments require beam monitors to operate in an intense neutron beam flux of >10E+7 neutrons per second per square centimeter. For instance, a 4 cm x 4 cm intense beam flux of 6.25 x 10E+7 n/s/cm2 at the Spallation Neutron Source will put a flux of 1.00 x 10E+9 n/s at the beam monitor. Currently available beam monitors with a typical efficiency of 1 x 10E-4 will need to be replaced in less than two years of operation due to wire and gas degradation issues. There is also a need at some instruments for beam position information that are beyond the capabilities of currently available He-3 and BF3 neutron beam monitors. ORDELA, Inc.’s research under USDOE SBIR Grant (DE-FG02-07ER84844) studied the feasibility of using pixel-cell technology for developing a new generation of stable, long-life neutron beam monitors. The research effort has led to the development and commercialization of advanced neutron beam detectors that will directly benefit the Spallation Neutron Source and other intense neutron sources such as the High Flux Isotope Reactor. A prototypical Pixel-Cell Neutron Beam Monitor was designed and constructed during this research effort. This prototype beam monitor was exposed to an intense neutron beam at the HFIR SNS HB-2 test beam site. Initial measurements on efficiency, uniformity across the detector, and position resolution yielded excellent results. The development and test results have provided the required data to initiate the fabrication and commercialization of this next generation of neutron-detector systems. ORDELA, Inc. has (1) identified low-cost design and fabrication strategies, (2) developed and built pixel-cell detectors and

  17. Advances in solid polymer electrolyte fuel cell technology with low-platinum-loading electrodes

    NASA Technical Reports Server (NTRS)

    Srinivasan, Supramaniam; Ticianelli, E. A.; Derouin, C. R.; Redondo, A.

    1987-01-01

    The Gemini Space program demonstrated the first major application of fuel cell systems. Solid polymer electrolyte fuel cells were used as auxiliary power sources in the spacecraft. There has been considerable progress in this technology since then, particularly with the substitution of Nafion for the polystyrene sulfonate membrane as the electrolyte. Until recently the performance was good only with high platinum loading (4 mg/sq cm) electrodes. Methods are presented to advance the technology by (1) use of low platinum loading (0.35 mg/sq cm) electrodes; (2) optimization of anode/membrane/cathode interfaces by hot pressing; (3) pressurization of reactant gases, which is most important when air is used as cathodic reactant; and (4) adequate humidification of reactant gases to overcome the water management problem. The high performance of the fuel cell with the low loading of platinum appears to be due to the extension of the three dimensional reaction zone by introduction of a proton conductor, Nafion. This was confirmed by cyclic voltammetry.

  18. Advanced Solar Cell and Array Technology for NASA Deep Space Missions

    NASA Technical Reports Server (NTRS)

    Piszczor, Michael; Benson, Scott; Scheiman, David; Finacannon, Homer; Oleson, Steve; Landis, Geoffrey

    2008-01-01

    A recent study by the NASA Glenn Research Center assessed the feasibility of using photovoltaics (PV) to power spacecraft for outer planetary, deep space missions. While the majority of spacecraft have relied on photovoltaics for primary power, the drastic reduction in solar intensity as the spacecraft moves farther from the sun has either limited the power available (severely curtailing scientific operations) or necessitated the use of nuclear systems. A desire by NASA and the scientific community to explore various bodies in the outer solar system and conduct "long-term" operations using using smaller, "lower-cost" spacecraft has renewed interest in exploring the feasibility of using photovoltaics for to Jupiter, Saturn and beyond. With recent advances in solar cell performance and continuing development in lightweight, high power solar array technology, the study determined that photovoltaics is indeed a viable option for many of these missions.

  19. Advances in photovoltaic technology

    NASA Technical Reports Server (NTRS)

    Landis, G. A.; Bailey, S. G.

    1992-01-01

    The advances in solar cell efficiency, radiation tolerance, and cost in the last 10 years are presented. The potential performance of thin-film solar cells in space is examined, and the cost and the historical trends in production capability of the photovoltaics industry are considered with respect to the needs of satellite solar power systems. Attention is given to single-crystal cells, concentrator and cascade cells, and thin-film solar cells.

  20. Advanced manufacturing: Technology diffusion

    SciTech Connect

    Tesar, A.

    1995-12-01

    In this paper we examine how manufacturing technology diffuses rom the developers of technology across national borders to those who do not have the capability or resources to develop advanced technology on their own. None of the wide variety of technology diffusion mechanisms discussed in this paper are new, yet the opportunities to apply these mechanisms are growing. A dramatic increase in technology diffusion occurred over the last decade. The two major trends which probably drive this increase are a worldwide inclination towards ``freer`` markets and diminishing isolation. Technology is most rapidly diffusing from the US In fact, the US is supplying technology for the rest of the world. The value of the technology supplied by the US more than doubled from 1985 to 1992 (see the Introduction for details). History shows us that technology diffusion is inevitable. It is the rates at which technologies diffuse to other countries which can vary considerably. Manufacturers in these countries are increasingly able to absorb technology. Their manufacturing efficiency is expected to progress as technology becomes increasingly available and utilized.

  1. Advanced Environmental Monitoring Technologies

    NASA Technical Reports Server (NTRS)

    Jan, Darrell

    2004-01-01

    Viewgraphs on Advanced Environmental Monitoring Technologies are presented. The topics include: 1) Monitoring & Controlling the Environment; 2) Illustrative Example: Canary 3) Ground-based Commercial Technology; 4) High Capability & Low Mass/Power + Autonomy = Key to Future SpaceFlight; 5) Current Practice: in Flight; 6) Current Practice: Post Flight; 7) Miniature Mass Spectrometer for Planetary Exploration and Long Duration Human Flight; 8) Hardware and Data Acquisition System; 9) 16S rDNA Phylogenetic Tree; and 10) Preview of Porter.

  2. Advanced solar dynamic technology program

    NASA Technical Reports Server (NTRS)

    Calogeras, James

    1990-01-01

    Viewgraphs and discussion on Advanced Solar Dynamic Technology Program are presented. Topics covered include: advanced solar dynamic technology program; advanced concentrators; advanced heat receivers; power conversion systems; dished all metal honeycomb sandwich panels; Stirling cavity heat pipe receiver; Brayton solar receiver; and thermal energy storage technology.

  3. Cell Phone-Based and Adherence Device Technologies for HIV Care and Treatment in Resource-Limited Settings: Recent Advances.

    PubMed

    Campbell, Jeffrey I; Haberer, Jessica E

    2015-12-01

    Numerous cell phone-based and adherence monitoring technologies have been developed to address barriers to effective HIV prevention, testing, and treatment. Because most people living with HIV and AIDS reside in resource-limited settings (RLS), it is important to understand the development and use of these technologies in RLS. Recent research on cell phone-based technologies has focused on HIV education, linkage to and retention in care, disease tracking, and antiretroviral therapy adherence reminders. Advances in adherence devices have focused on real-time adherence monitors, which have been used for both antiretroviral therapy and pre-exposure prophylaxis. Real-time monitoring has recently been combined with cell phone-based technologies to create real-time adherence interventions using short message service (SMS). New developments in adherence technologies are exploring ingestion monitoring and metabolite detection to confirm adherence. This article provides an overview of recent advances in these two families of technologies and includes research on their acceptability and cost-effectiveness when available. It additionally outlines key challenges and needed research as use of these technologies continues to expand and evolve.

  4. Advanced composites technology program

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr.

    1993-01-01

    This paper provides a brief overview of the NASA Advanced Composites Technology (ACT) Program. Critical technology issues that must be addressed and solved to develop composite primary structures for transport aircraft are delineated. The program schedule and milestones are included. Work completed in the first 3 years of the program indicates the potential for achieving composite structures that weigh less and are cost effective relative to conventional aluminum structure. Selected technical accomplishments are noted. Readers who are seeking more in-depth technical information should study the other papers included in these proceedings.

  5. Advanced Technology Vehicle Testing

    SciTech Connect

    James Francfort

    2004-06-01

    The goal of the U.S. Department of Energy's Advanced Vehicle Testing Activity (AVTA) is to increase the body of knowledge as well as the awareness and acceptance of electric drive and other advanced technology vehicles (ATV). The AVTA accomplishes this goal by testing ATVs on test tracks and dynamometers (Baseline Performance testing), as well as in real-world applications (Fleet and Accelerated Reliability testing and public demonstrations). This enables the AVTA to provide Federal and private fleet managers, as well as other potential ATV users, with accurate and unbiased information on vehicle performance and infrastructure needs so they can make informed decisions about acquiring and operating ATVs. The ATVs currently in testing include vehicles that burn gaseous hydrogen (H2) fuel and hydrogen/CNG (H/CNG) blended fuels in internal combustion engines (ICE), and hybrid electric (HEV), urban electric, and neighborhood electric vehicles. The AVTA is part of DOE's FreedomCAR and Vehicle Technologies Program.

  6. Advanced geothermal technologies

    NASA Astrophysics Data System (ADS)

    Whetten, J. T.; Murphy, H. D.; Hanold, R. J.; Myers, C. W.; Dunn, J. C.

    Research and development in advanced technologies for geothermal energy production continue to increase the energy production options for the Nation. The high-risk investment over the past few years by the U.S. Department of Energy in geopressured, hot dry rock, and magma energy resources is producing new means to lower production costs and to take advantage of these resources. The Nation has far larger and more regionally extensive geothermal resources than heretofore realized. At the end of a short 30-day closed-loop flow test, the manmade hot dry rock reservoir at Fenton Hill, New Mexico was producing 10 MW thermal, and still climbing, proving the technical feasibility of this new technology. The scientific feasibility of magma energy extraction was demonstrated, and new field tests to evaluate this technology are planned. Analysis and field tests confirm the viability of geopressured-geothermal energy and the prospect that many dry-hole or depleted petroleum wells can be turned into producing geopressured-geothermal wells. Technological advances achieved through hot dry rock, magma, geopressured, and other geothermal research are making these resources and conventional hydrothermal resources more competitive.

  7. Advanced composite fuselage technology

    NASA Technical Reports Server (NTRS)

    Ilcewicz, Larry B.; Smith, Peter J.; Horton, Ray E.

    1993-01-01

    Boeing's ATCAS program has completed its third year and continues to progress towards a goal to demonstrate composite fuselage technology with cost and weight advantages over aluminum. Work on this program is performed by an integrated team that includes several groups within The Boeing Company, industrial and university subcontractors, and technical support from NASA. During the course of the program, the ATCAS team has continued to perform a critical review of composite developments by recognizing advances in metal fuselage technology. Despite recent material, structural design, and manufacturing advancements for metals, polymeric matrix composite designs studied in ATCAS still project significant cost and weight advantages for future applications. A critical path to demonstrating technology readiness for composite transport fuselage structures was created to summarize ATCAS tasks for Phases A, B, and C. This includes a global schedule and list of technical issues which will be addressed throughout the course of studies. Work performed in ATCAS since the last ACT conference is also summarized. Most activities relate to crown quadrant manufacturing scaleup and performance verification. The former was highlighted by fabricating a curved, 7 ft. by 10 ft. panel, with cocured hat-stiffeners and cobonded J-frames. In building to this scale, process developments were achieved for tow-placed skins, drape formed stiffeners, braided/RTM frames, and panel cure tooling. Over 700 tests and supporting analyses have been performed for crown material and design evaluation, including structural tests that demonstrated limit load requirements for severed stiffener/skin failsafe damage conditions. Analysis of tests for tow-placed hybrid laminates with large damage indicates a tensile fracture toughness that is higher than that observed for advanced aluminum alloys. Additional recent ATCAS achievements include crown supporting technology, keel quadrant design evaluation, and

  8. Advanced Technology Vehicle Testing

    SciTech Connect

    James Francfort

    2003-11-01

    The light-duty vehicle transportation sector in the United States depends heavily on imported petroleum as a transportation fuel. The Department of Energy’s Advanced Vehicle Testing Activity (AVTA) is testing advanced technology vehicles to help reduce this dependency, which would contribute to the economic stability and homeland security of the United States. These advanced technology test vehicles include internal combustion engine vehicles operating on 100% hydrogen (H2) and H2CNG (compressed natural gas) blended fuels, hybrid electric vehicles, neighborhood electric vehicles, urban electric vehicles, and electric ground support vehicles. The AVTA tests and evaluates these vehicles with closed track and dynamometer testing methods (baseline performance testing) and accelerated reliability testing methods (accumulating lifecycle vehicle miles and operational knowledge within 1 to 1.5 years), and in normal fleet environments. The Arizona Public Service Alternative Fuel Pilot Plant and H2-fueled vehicles are demonstrating the feasibility of using H2 as a transportation fuel. Hybrid, neighborhood, and urban electric test vehicles are demonstrating successful applications of electric drive vehicles in various fleet missions. The AVTA is also developing electric ground support equipment (GSE) test procedures, and GSE testing will start during the fall of 2003. All of these activities are intended to support U.S. energy independence. The Idaho National Engineering and Environmental Laboratory manages these activities for the AVTA.

  9. Advanced gearbox technology

    NASA Technical Reports Server (NTRS)

    Anderson, N. E.; Cedoz, R. W.; Salama, E. E.; Wagner, D. A.

    1987-01-01

    An advanced 13,000 HP, counterrotating (CR) gearbox was designed and successfully tested to provide a technology base for future designs of geared propfan propulsion systems for both commercial and military aircraft. The advanced technology CR gearbox was designed for high efficiency, low weight, long life, and improved maintainability. The differential planetary CR gearbox features double helical gears, double row cylindrical roller bearings integral with planet gears, tapered roller prop support bearings, and a flexible ring gear and diaphragm to provide load sharing. A new Allison propfan back-to-back gearbox test facility was constructed. Extensive rotating and stationary instrumentation was used to measure temperature, strain, vibration, deflection and efficiency under representative flight operating conditions. The tests verified smooth, efficient gearbox operation. The highly-instrumented advanced CR gearbox was successfully tested to design speed and power (13,000 HP), and to a 115 percent overspeed condition. Measured CR gearbox efficiency was 99.3 percent at the design point based on heat loss to the oil. Tests demonstrated low vibration characteristics of double helical gearing, proper gear tooth load sharing, low stress levels, and the high load capacity of the prop tapered roller bearings. Applied external prop loads did not significantly affect gearbox temperature, vibration, or stress levels. Gearbox hardware was in excellent condition after the tests with no indication of distress.

  10. Advanced optical instruments technology

    NASA Technical Reports Server (NTRS)

    Shao, Mike; Chrisp, Michael; Cheng, Li-Jen; Eng, Sverre; Glavich, Thomas; Goad, Larry; Jones, Bill; Kaarat, Philip; Nein, Max; Robinson, William

    1992-01-01

    The science objectives for proposed NASA missions for the next decades push the state of the art in sensitivity and spatial resolution over a wide range of wavelengths, including the x-ray to the submillimeter. While some of the proposed missions are larger and more sensitive versions of familiar concepts, such as the next generation space telescope, others use concepts, common on the Earth, but new to space, such as optical interferometry, in order to provide spatial resolutions impossible with other concepts. However, despite their architecture, the performance of all of the proposed missions depends critically on the back-end instruments that process the collected energy to produce scientifically interesting outputs. The Advanced Optical Instruments Technology panel was chartered with defining technology development plans that would best improve optical instrument performance for future astrophysics missions. At this workshop the optical instrument was defined as the set of optical components that reimage the light from the telescope onto the detectors to provide information about the spatial, spectral, and polarization properties of the light. This definition was used to distinguish the optical instrument technology issues from those associated with the telescope, which were covered by a separate panel. The panel identified several areas for optical component technology development: diffraction gratings; tunable filters; interferometric beam combiners; optical materials; and fiber optics. The panel also determined that stray light suppression instruments, such as coronagraphs and nulling interferometers, were in need of general development to support future astrophysics needs.

  11. State Technologies Advancement Collaborative

    SciTech Connect

    David S. Terry

    2012-01-30

    The U. S. Department of Energy (DOE), National Association of State Energy Officials (NASEO), and Association of State Energy Research and Technology Transfer Institutions (ASERTTI) signed an intergovernmental agreement on November 14, 2002, that allowed states and territories and the Federal Government to better collaborate on energy research, development, demonstration and deployment (RDD&D) projects. The agreement established the State Technologies Advancement Collaborative (STAC) which allowed the states and DOE to move RDD&D forward using an innovative competitive project selection and funding process. A cooperative agreement between DOE and NASEO served as the contracting instrument for this innovative federal-state partnership obligating funds from DOE's Office of Energy Efficiency and Renewable Energy and Office of Fossil Energy to plan, fund, and implement RDD&D projects that were consistent with the common priorities of the states and DOE. DOE's Golden Field Office provided Federal oversight and guidance for the STAC cooperative agreement. The STAC program was built on the foundation of prior Federal-State efforts to collaborate on and engage in joint planning for RDD&D. Although STAC builds on existing, successful programs, it is important to note that it was not intended to replace other successful joint DOE/State initiatives such as the State Energy Program or EERE Special Projects. Overall the STAC process was used to fund, through three competitive solicitations, 35 successful multi-state research, development, deployment, and demonstration projects with an overall average non-federal cost share of 43%. Twenty-two states were awarded at least one prime contract, and organizations in all 50 states and some territories were involved as subcontractors in at least one STAC project. Projects were funded in seven program areas: (1) Building Technologies, (2) Industrial Technologies, (3) Transportation Technologies, (4) Distributed Energy Resources, (5

  12. Monolithic solid oxide fuel cell technology advancement for coal- based power generation. Quarterly report, December 1991

    SciTech Connect

    Not Available

    1992-01-15

    The program is conducted by a team consisting of AiResearch Los Angeles Division of Allied-Signal Aerospace Company and Argonne National Laboratory (ANL). The objective of the program is to advance materials and fabrication methodologies to develop a monolithic solid oxide fuel cell (MSOFC) system capable of meeting performance, life, and cost goals for coal-based power generation. The program focuses on materials research and development, fabrication process development, cell/stack performance testing and characterization, cost and system analysis, and quality development.

  13. Monolithic solid oxide fuel cell technology advancement for coal- based power generation

    SciTech Connect

    Not Available

    1992-01-15

    The program is conducted by a team consisting of AiResearch Los Angeles Division of Allied-Signal Aerospace Company and Argonne National Laboratory (ANL). The objective of the program is to advance materials and fabrication methodologies to develop a monolithic solid oxide fuel cell (MSOFC) system capable of meeting performance, life, and cost goals for coal-based power generation. The program focuses on materials research and development, fabrication process development, cell/stack performance testing and characterization, cost and system analysis, and quality development.

  14. Recent findings and technological advances in phosphoproteomics for cells and tissues.

    PubMed

    von Stechow, Louise; Francavilla, Chiara; Olsen, Jesper V

    2015-01-01

    Site-specific phosphorylation is a fast and reversible covalent post-translational modification that is tightly regulated in cells. The cellular machinery of enzymes that write, erase and read these modifications (kinases, phosphatases and phospho-binding proteins) is frequently deregulated in different diseases, including cancer. Large-scale studies of phosphoproteins - termed phosphoproteomics - strongly rely on the use of high-performance mass spectrometric instrumentation. This powerful technology has been applied to study a great number of phosphorylation-based phenotypes. Nevertheless, many technical and biological challenges have to be overcome to identify biologically relevant phosphorylation sites in cells and tissues. This review describes different technological strategies to identify and quantify phosphorylation sites with high accuracy, without significant loss of analysis speed and reproducibility in tissues and cells. Moreover, computational tools for analysis, integration and biological interpretation of phosphorylation events are discussed.

  15. Recent findings and technological advances in phosphoproteomics for cells and tissues

    PubMed Central

    von Stechow, Louise; Francavilla, Chiara; Olsen, Jesper V

    2015-01-01

    Site-specific phosphorylation is a fast and reversible covalent post-translational modification that is tightly regulated in cells. The cellular machinery of enzymes that write, erase and read these modifications (kinases, phosphatases and phospho-binding proteins) is frequently deregulated in different diseases, including cancer. Large-scale studies of phosphoproteins – termed phosphoproteomics – strongly rely on the use of high-performance mass spectrometric instrumentation. This powerful technology has been applied to study a great number of phosphorylation-based phenotypes. Nevertheless, many technical and biological challenges have to be overcome to identify biologically relevant phosphorylation sites in cells and tissues. This review describes different technological strategies to identify and quantify phosphorylation sites with high accuracy, without significant loss of analysis speed and reproducibility in tissues and cells. Moreover, computational tools for analysis, integration and biological interpretation of phosphorylation events are discussed. PMID:26400465

  16. USMC UGS technology advancements

    NASA Astrophysics Data System (ADS)

    Hartup, David C.; Barr, Michael E.; Hirz, Philip M.; Kipp, Jason; Fishburn, Thomas A.; Waller, Ezra S.; Marks, Brian A.

    2008-04-01

    Technology advancements for the USMC UGS system are described. Integration of the ARL Blue Radio/CSR into the System Controller and Radio Repeater permit the TRSS system to operate seamlessly within the Family of UGS concept. In addition to the Blue Radio/CSR, the TRSS system provides VHF and SATCOM radio links. The TRSS system is compatible with a wide range of imagers, including those with both analog and digital interfaces. The TRSS System Controller permits simultaneous monitoring of 2 camera inputs. To complement enhanced compatibility and improved processing, the mechanical housing of the TRSS System Controller has been updated. The SDR-II, a system monitoring device, also incorporates four Blue Radio/CSRs along with other communication capabilities, making it an ideal choice for a monitoring station within the Family of UGS. Field testing of L-3 Nova's UGS system at YPG has shown flawless performance, capturing all 126 targets.

  17. Recent advances in yeast cell-surface display technologies for waste biorefineries.

    PubMed

    Liu, Zhuo; Ho, Shih-Hsin; Hasunuma, Tomohisa; Chang, Jo-Shu; Ren, Nan-Qi; Kondo, Akihiko

    2016-09-01

    Waste biorefinery aims to maximize the output of value-added products from various artificial/agricultural wastes by using integrated bioprocesses. To make waste biorefinery economically feasible, it is thus necessary to develop a low-cost, environment-friendly technique to perform simultaneous biodegradation and bioconversion of waste materials. Cell-surface display engineering is a novel, cost-effective technique that can auto-immobilize proteins on the cell exterior of microorganisms, and has been applied for use with waste biofinery. Through tethering different enzymes (e.g., cellulase, lipase, and protease) or metal-binding peptides on cell surfaces, various yeast strains can effectively produce biofuels and biochemicals from sugar/protein-rich waste materials, catalyze waste oils into biodiesels, or retrieve heavy metals from wastewater. This review critically summarizes recent applications of yeast cell-surface display on various types of waste biorefineries, highlighting its potential and future challenges with regard to commercializing this technology. PMID:27039354

  18. Recent advances in yeast cell-surface display technologies for waste biorefineries.

    PubMed

    Liu, Zhuo; Ho, Shih-Hsin; Hasunuma, Tomohisa; Chang, Jo-Shu; Ren, Nan-Qi; Kondo, Akihiko

    2016-09-01

    Waste biorefinery aims to maximize the output of value-added products from various artificial/agricultural wastes by using integrated bioprocesses. To make waste biorefinery economically feasible, it is thus necessary to develop a low-cost, environment-friendly technique to perform simultaneous biodegradation and bioconversion of waste materials. Cell-surface display engineering is a novel, cost-effective technique that can auto-immobilize proteins on the cell exterior of microorganisms, and has been applied for use with waste biofinery. Through tethering different enzymes (e.g., cellulase, lipase, and protease) or metal-binding peptides on cell surfaces, various yeast strains can effectively produce biofuels and biochemicals from sugar/protein-rich waste materials, catalyze waste oils into biodiesels, or retrieve heavy metals from wastewater. This review critically summarizes recent applications of yeast cell-surface display on various types of waste biorefineries, highlighting its potential and future challenges with regard to commercializing this technology.

  19. Technological advances in adoptive immunotherapy.

    PubMed

    Oelke, Mathias; Krueger, Christine; Schneck, Jonathan P

    2005-01-01

    Adoptive immunotherapy is an attractive and elegant strategy for treating a variety of life-threatening diseases. Several approaches have been developed to generate antigen-specific CD4+ and CD8+ T cells for adoptive T-cell therapy in cancer and infectious diseases. Currently, many approaches are based on either the use of autologous peptide pulsed dendritic cells as antigen-presenting cells or nonspecific expansion of T cells. Unfortunately, current approaches lack the ability to serve as reproducible and economically viable methods. Several groups are developing new artificial approaches to overcome problems associated with dendritic cells and the nonspecific expansion of T-cell clones in order to make adoptive immunotherapy more feasible and effective. Thus, by increasing the availability of adoptive immunotherapy, we will be able to better determine the efficacy of the approaches in the treatment of a variety of diseases. In this review, we focus on technological advances that will facilitate adoptive immunotherapy. Specifically, we summarize current strategies which are either based on artificial antigen-presenting cells or on T-cell receptor gene transfer. PMID:15753966

  20. Benefits of advanced technology in industrial cogeneration

    NASA Technical Reports Server (NTRS)

    Barna, G. J.; Burns, R. K.

    1979-01-01

    This broad study is aimed at identifying the most attractive advanced energy conversion systems for industrial cogeneration for the 1985 to 2000 time period and assessing the advantages of advanced technology systems compared to using today's commercially available technology. Energy conversion systems being studied include those using steam turbines, open cycle gas turbines, combined cycles, diesel engines, Stirling engines, closed cycle gas turbines, phosphoric acid and molten carbonate fuel cells and thermionics. Specific cases using today's commercially available technology are being included to serve as a baseline for assessing the advantages of advanced technology.

  1. Monolithic solid oxide fuel cell technology advancement for coal-based power generation. Final report, September 1989--March 1994

    SciTech Connect

    Not Available

    1994-05-01

    This project has successfully advanced the technology for MSOFCs for coal-based power generation. Major advances include: tape-calendering processing technology, leading to 3X improved performance at 1000 C; stack materials formulations and designs with sufficiently close thermal expansion match for no stack damage after repeated thermal cycling in air; electrically conducting bonding with excellent structural robustness; and sealants that form good mechanical seals for forming manifold structures. A stack testing facility was built for high-spower MSOFC stacks. Comprehensive models were developed for fuel cell performance and for analyzing structural stresses in multicell stacks and electrical resistance of various stack configurations. Mechanical and chemical compatibility properties of fuel cell components were measured; they show that the baseline Ca-, Co-doped interconnect expands and weakens in hydrogen fuel. This and the failure to develop adequate sealants were the reason for performance shortfalls in large stacks. Small (1-in. footprint) two-cell stacks were fabricated which achieved good performance (average area-specific-resistance 1.0 ohm-cm{sup 2} per cell); however, larger stacks had stress-induced structural defects causing poor performance.

  2. Advanced Adaptive Optics Technology Development

    SciTech Connect

    Olivier, S

    2001-09-18

    The NSF Center for Adaptive Optics (CfAO) is supporting research on advanced adaptive optics technologies. CfAO research activities include development and characterization of micro-electro-mechanical systems (MEMS) deformable mirror (DM) technology, as well as development and characterization of high-resolution adaptive optics systems using liquid crystal (LC) spatial light modulator (SLM) technology. This paper presents an overview of the CfAO advanced adaptive optics technology development activities including current status and future plans.

  3. Advances in cell culture

    SciTech Connect

    Maramorosch, K. )

    1987-01-01

    This book presents papers on advances in cell culture. Topics covered include: Genetic changes in the influenza viruses during growth in cultured cells; The biochemistry and genetics of mosquito cells in culture; and Tree tissue culture applications.

  4. Microbial electrolysis cells turning to be versatile technology: recent advances and future challenges.

    PubMed

    Zhang, Yifeng; Angelidaki, Irini

    2014-06-01

    Microbial electrolysis cells (MECs) are an electricity-mediated microbial bioelectrochemical technology, which is originally developed for high-efficiency biological hydrogen production from waste streams. Compared to traditional biological technologies, MECs can overcome thermodynamic limitations and achieve high-yield hydrogen production from wide range of organic matters at relatively mild conditions. This approach greatly reduces the electric energy cost for hydrogen production in contrast to direct water electrolysis. In addition to hydrogen production, MECs may also support several energetically unfavorable biological/chemical reactions. This unique advantage of MECs has led to several alternative applications such as chemicals synthesis, recalcitrant pollutants removal, resources recovery, bioelectrochemical research platform and biosensors, which have greatly broaden the application scopes of MECs. MECs are becoming a versatile platform technology and offer a new solution for emerging environmental issues related to waste streams treatment and energy and resource recovery. Different from previous reviews that mainly focus on hydrogen production, this paper provides an up-to-date review of all the new applications of MECs and their resulting performance, current challenges and prospects of future. PMID:24631941

  5. Microbial electrolysis cells turning to be versatile technology: recent advances and future challenges.

    PubMed

    Zhang, Yifeng; Angelidaki, Irini

    2014-06-01

    Microbial electrolysis cells (MECs) are an electricity-mediated microbial bioelectrochemical technology, which is originally developed for high-efficiency biological hydrogen production from waste streams. Compared to traditional biological technologies, MECs can overcome thermodynamic limitations and achieve high-yield hydrogen production from wide range of organic matters at relatively mild conditions. This approach greatly reduces the electric energy cost for hydrogen production in contrast to direct water electrolysis. In addition to hydrogen production, MECs may also support several energetically unfavorable biological/chemical reactions. This unique advantage of MECs has led to several alternative applications such as chemicals synthesis, recalcitrant pollutants removal, resources recovery, bioelectrochemical research platform and biosensors, which have greatly broaden the application scopes of MECs. MECs are becoming a versatile platform technology and offer a new solution for emerging environmental issues related to waste streams treatment and energy and resource recovery. Different from previous reviews that mainly focus on hydrogen production, this paper provides an up-to-date review of all the new applications of MECs and their resulting performance, current challenges and prospects of future.

  6. Recent advances in solid polymer electrolyte fuel cell technology with low platinum loading electrodes

    NASA Technical Reports Server (NTRS)

    Srinivasan, Supramaniam; Manko, David J.; Enayatullah, Mohammad; Appleby, A. John

    1989-01-01

    High power density fuel cell systems for defense and civilian applications are being developed. Taking into consideration the main causes for efficiency losses (activation, mass transport and ohmic overpotentials) the only fuel cell systems capable of achieving high power densities are the ones with alkaline and solid polymer electrolyte. High power densities (0.8 W/sq cm at 0.8 V and 1 A/sq cm with H2 and O2 as reactants), were already used in NASA's Apollo and Space Shuttle flights as auxiliary power sources. Even higher power densities (4 W/sq cm - i.e., 8 A sq cm at 0.5 V) were reported by the USAF/International Fuel Cells in advanced versions of the alkaline system. High power densities (approximately 1 watt/sq cm) in solid polymer electrolyte fuel cells with ten times lower platinum loading in the electrodes (i.e., 0.4 mg/sq cm) were attained. It is now possible to reach a cell potential of 0.620 V at a current density of 2 A/sq cm and at a temperature of 95 C and pressure of 4/5 atm with H2/O2 as reactants. The slope of the linear region of the potential-current density plot for this case is 0.15 ohm-sq cm. With H2/air as reactants and under the same operating conditions, mass transport limitations are encountered at current densities above 1.4 A/sq cm. Thus, the cell potential at 1 A/sq cm with H2/air as reactants is less than that with H2/O2 as reactants by 40 mV, which is the expected value based on electrode kinetics of the oxygen reduction reaction, and at 2 A/sq cm with H2/air as reactant is less than the corresponding value with H2/O2 as reactants by 250 mV, which is due to the considerably greater mass transport limitations in the former case.

  7. Technological advances for deciphering the complexity of psychiatric disorders: merging proteomics with cell biology.

    PubMed

    Wesseling, Hendrik; Guest, Paul C; Lago, Santiago G; Bahn, Sabine

    2014-08-01

    Proteomic studies have increased our understanding of the molecular pathways affected in psychiatric disorders. Mass spectrometry and two-dimensional gel electrophoresis analyses of post-mortem brain samples from psychiatric patients have revealed effects on synaptic, cytoskeletal, antioxidant and mitochondrial protein networks. Multiplex immunoassay profiling studies have found alterations in hormones, growth factors, transport and inflammation-related proteins in serum and plasma from living first-onset patients. Despite these advances, there are still difficulties in translating these findings into platforms for improved treatment of patients and for discovery of new drugs with better efficacy and side effect profiles. This review describes how the next phase of proteomic investigations in psychiatry should include stringent replication studies for validation of biomarker candidates and functional follow-up studies which can be used to test the impact on physiological function. All biomarker candidates should now be tested in series with traditional and emerging cell biological approaches. This should include investigations of the effects of post-translational modifications, protein dynamics and network analyses using targeted proteomic approaches. Most importantly, there is still an urgent need for development of disease-relevant cellular models for improved translation of proteomic findings into a means of developing novel drug treatments for patients with these life-altering disorders.

  8. Advanced Materials Technology

    NASA Technical Reports Server (NTRS)

    Blankenship, C. P. (Compiler); Teichman, L. A. (Compiler)

    1982-01-01

    Composites, polymer science, metallic materials (aluminum, titanium, and superalloys), materials processing technology, materials durability in the aerospace environment, ceramics, fatigue and fracture mechanics, tribology, and nondestructive evaluation (NDE) are discussed. Research and development activities are introduced to the nonaerospace industry. In order to provide a convenient means to help transfer aerospace technology to the commercial mainstream in a systematic manner.

  9. Advanced interdisciplinary technologies

    NASA Technical Reports Server (NTRS)

    Anderson, John L.

    1990-01-01

    The following topics are presented in view graph form: (1) breakthrough trust (space research and technology assessment); (2) bionics (technology derivatives from biological systems); (3) biodynamics (modeling of human biomechanical performance based on anatomical data); and (4) tethered atmospheric research probes.

  10. Advanced technology composite aircraft structures

    NASA Technical Reports Server (NTRS)

    Ilcewicz, Larry B.; Walker, Thomas H.

    1991-01-01

    Work performed during the 25th month on NAS1-18889, Advanced Technology Composite Aircraft Structures, is summarized. The main objective of this program is to develop an integrated technology and demonstrate a confidence level that permits the cost- and weight-effective use of advanced composite materials in primary structures of future aircraft with the emphasis on pressurized fuselages. The period from 1-31 May 1991 is covered.

  11. New advances in erectile technology.

    PubMed

    Stein, Marshall J; Lin, Haocheng; Wang, Run

    2014-02-01

    New discoveries and technological advances in medicine are rapid. The role of technology in the treatment of erectile dysfunction (ED) will be widened and more options will be available in the years to come. These erectile technologies include external penile support devices, penile vibrators, low intensity extracorporeal shockwave, tissue engineering, nanotechnology and endovascular technology. Even for matured treatment modalities for ED, such as vacuum erectile devices and penile implants, there is new scientific information and novel technology available to improve their usage and to stimulate new ideas. We anticipate that erectile technologies may revolutionize ED treatment and in the very near future ED may become a curable condition.

  12. Advanced Modular Inverter Technology Development

    SciTech Connect

    Adam Szczepanek

    2006-02-04

    Electric and hybrid-electric vehicle systems require an inverter to convert the direct current (DC) output of the energy generation/storage system (engine, fuel cells, or batteries) to the alternating current (AC) that vehicle propulsion motors use. Vehicle support systems, such as lights and air conditioning, also use the inverter AC output. Distributed energy systems require an inverter to provide the high quality AC output that energy system customers demand. Today's inverters are expensive due to the cost of the power electronics components, and system designers must also tailor the inverter for individual applications. Thus, the benefits of mass production are not available, resulting in high initial procurement costs as well as high inverter maintenance and repair costs. Electricore, Inc. (www.electricore.org) a public good 501 (c) (3) not-for-profit advanced technology development consortium assembled a highly qualified team consisting of AeroVironment Inc. (www.aerovironment.com) and Delphi Automotive Systems LLC (Delphi), (www.delphi.com), as equal tiered technical leads, to develop an advanced, modular construction, inverter packaging technology that will offer a 30% cost reduction over conventional designs adding to the development of energy conversion technologies for crosscutting applications in the building, industry, transportation, and utility sectors. The proposed inverter allows for a reduction of weight and size of power electronics in the above-mentioned sectors and is scalable over the range of 15 to 500kW. The main objective of this program was to optimize existing AeroVironment inverter technology to improve power density, reliability and producibility as well as develop new topology to reduce line filter size. The newly developed inverter design will be used in automotive and distribution generation applications. In the first part of this program the high-density power stages were redesigned, optimized and fabricated. One of the main tasks

  13. Advanced composites technology

    SciTech Connect

    DeTeresa, S J; Groves, S E; Sanchez, R J

    1998-10-01

    The development of fiber composite components in next-generation munitions, such as sabots for kinetic energy penetrators and lightweight cases for advanced artillery projectiles, relies on design trade-off studies using validated computer code simulations. We are developing capabilities to determine the failure of advanced fiber composites under multiaxial stresses to critically evaluate three-dimensional failure models and develop new ones if necessary. The effects of superimposed hydrostatic pressure on failure of composites are being investigated using a high-pressure testing system that incorporates several unique features. Several improvements were made to the system this year, and we report on the first tests of both isotropic and fiber composite materials. The preliminary results indicate that pressure has little effect on longitudinal compression strength of unidirectional composites, but issues with obtaining reliable failures in these materials still remain to be resolved. The transverse compression strength was found to be significantly enhanced by pressure, and the trends observed for this property and the longitudinal strength are in agreement with recent models for failure of fiber composites.

  14. Recent advances in solid polymer electrolyte fuel cell technology with low platinum loading electrodes

    NASA Technical Reports Server (NTRS)

    Srinivasan, Supramaniam; Manko, David J.; Koch, Hermann; Enayetullah, Mohammad A.; Appleby, A. John

    1989-01-01

    Of all the fuel cell systems only alkaline and solid polymer electrolyte fuel cells are capable of achieving high power densities (greater than 1 W/sq cm) required for terrestrial and extraterrestrial applications. Electrode kinetic criteria for attaining such high power densities are discussed. Attainment of high power densities in solid polymer electrolyte fuel cells has been demonstrated earlier by different groups using high platinum loading electrodes (4 mg/sq cm). Recent works at Los Alamos National Laboratory and at Texas A and M University (TAMU) demonstrated similar performance for solid polymer electrolyte fuel cells with ten times lower platinum loading (0.45 mg/sq cm) in the electrodes. Some of the results obtained are discussed in terms of the effects of type and thickness of membrane and of the methods platinum localization in the electrodes on the performance of a single cell.

  15. [Technological advances in neurorehabilitation].

    PubMed

    Gutiérrez-Martínez, Josefina; Núñez-Gaona, Marco Antonio; Carrillo-Mora, Paul

    2014-07-01

    Neurological rehabilitation arose as formal method in the 60's, for the therapeutic treatment of patients with stroke or spinal cord injury, which develop severe sequelae that affect their motor and sensory abilities. Although the Central Nervous System has plasticity mechanisms for spontaneous recovery, a high percentage of patients should receive specialized therapies to regain motor function, such as Constraint Induced Movement Therapy or Upright physical Therapy. The neurorehabilitation has undergone drastic changes over the last two decades due to the incorporation of computer and robotic electronic devices, designed to produce positive changes in cortical excitability of the cerebral hemisphere damaged and so to improve neuroplasticity. Among equipment, we can mention those for electrotherapy devices, apparatus for transcranial magnetic stimulation, the robotic lower limb orthoses, robot for upper limb training, systems for functional electrical stimulation, neuroprosthesis and brain computer interfaces. These devices have caused controversy because of its application and benefits reported in the literature. The aim of Neurorehabilitation technologies is to take advantage of the functional neuromuscular structures preserved, and they compensate or re-learn the functions that previously made the damaged areas. The purpose of this article is to mention some clinical applications and benefits that these technologies offer to patients with neuronal injury.

  16. Advances in energy technology

    SciTech Connect

    Sauer, H.J. Jr.; Hegler, B.E.

    1982-01-01

    Papers on various topics of energy conservation, new passive solar heating and storage devices, governmental particiaption in developing energy technologies, and the development of diverse energy sources and safety features are presented. Attention is given to recent shifts in the federal and state government roles in energy research, development and economic incentives. The applications of passive solar walls, flat plate collectors and trombe walls as retorfits for houses, institutions, and industries were examined. Attention was given to the implementation of wind power by a zoo and the use of spoilers as speed control devices in a Darrieus wind turbine. Aspects of gasohol, coal, synfuel, and laser-pyrolyzed coal products use are investigated. Finally, the economic, social, and political factors influencing energy system selection are explored, together with conservation practices in housing, government, and industry, and new simulators for enhancing nuclear power plant safety.

  17. Current metabolomics: technological advances.

    PubMed

    Putri, Sastia P; Yamamoto, Shinya; Tsugawa, Hiroshi; Fukusaki, Eiichiro

    2013-07-01

    Metabolomics, the global quantitative assessment of metabolites in a biological system, has played a pivotal role in various fields of science in the post-genomic era. Metabolites are the result of the interaction of the system's genome with its environment and are not merely the end product of gene expression, but also form part of the regulatory system in an integrated manner. Therefore, metabolomics is often considered a powerful tool to provide an instantaneous snapshot of the physiology of a cell. The power of metabolomics lies on the acquisition of analytical data in which metabolites in a cellular system are quantified, and the extraction of the most meaningful elements of the data by using various data analysis tool. In this review, we discuss the latest development of analytical techniques and data analyses methods in metabolomics study.

  18. Advanced Aerogel Technology

    NASA Technical Reports Server (NTRS)

    Jones, Steven

    2013-01-01

    The JPL Aerogel Laboratory has made aerogels for NASA flight missions, e.g., Stardust, 2003 Mars Exploration Rovers and the 2011 Mars Science Laboratory, as well as NASA research projects for the past 14 years. During that time it has produced aerogels of a range of shapes, sizes, densities and compositions. Research is ongoing in the development of aerogels for future sample capture and return missions and for thermal insulation for both spacecraft and scientific instruments. For the past several years, the JPL Aerogel Laboratory has been developing, producing and testing a new composite material for use as the high temperature thermal insulation in the Advanced Sterling Radioisotope Generator (ASRG) being developed by Lockheed Martin and NASA. The composite is made up of a glass fiber felt, silica aerogel, Titania powder, and silica powder. The oxide powders are included to reduce irradiative heat transport at elevated temperatures. These materials have thermal conductivity values that are the same as the best commercially produced high temperature insulation materials, and yet are 40% lighter. By greatly reducing the amount of oxide powder in the composite, the density, and therefore for the value of the thermal conductivity, would be reduced. The JPL Aerogel Laboratory has experimented with using glass fiber felt, expanded glass fiber felt and loose fibers to add structural integrity to silica aerogels. However, this work has been directed toward high temperature applications. By conducting a brief investigation of the optimal combination of fiber reinforcement and aerogel density, a durable, extremely efficient thermal insulation material for ambient temperature applications would be produced. If a transparent thermal insulation is desired, then aerogel is an excellent candidate material. At typical ambient temperatures, silica aerogel prevents the transport of heat via convection and conduction due to its highly porous nature. To prevent irradiative thermal

  19. Advanced Technology for Engineering Education

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

    1998-01-01

    This document contains the proceedings of the Workshop on Advanced Technology for Engineering Education, held at the Peninsula Graduate Engineering Center, Hampton, Virginia, February 24-25, 1998. The workshop was jointly sponsored by the University of Virginia's Center for Advanced Computational Technology and NASA. Workshop attendees came from NASA, other government agencies, industry and universities. The objectives of the workshop were to assess the status of advanced technologies for engineering education and to explore the possibility of forming a consortium of interested individuals/universities for curriculum reform and development using advanced technologies. The presentations covered novel delivery systems and several implementations of new technologies for engineering education. Certain materials and products are identified in this publication in order to specify adequately the materials and products that were investigated in the research effort. In no case does such identification imply recommendation or endorsement of products by NASA, nor does it imply that the materials and products are the only ones or the best ones available for this purpose. In many cases equivalent materials and products are available and would probably produce equivalent results.

  20. Energy Storage (II): Developing Advanced Technologies

    ERIC Educational Resources Information Center

    Robinson, Arthur L

    1974-01-01

    Energy storage, considered by some scientists to be the best technological and economic advancement after advanced nuclear power, still rates only modest funding for research concerning the development of advanced technologies. (PEB)

  1. Advanced Operating System Technologies

    NASA Astrophysics Data System (ADS)

    Cittolin, Sergio; Riccardi, Fabio; Vascotto, Sandro

    . Our work started in the second half of 1994, with a research agreement between CERN and Chorus Systemes (France), world leader in the micro-kernel OS technology. The Chorus OS is targeted to distributed real-time applications, and it can very efficiently support different "OS personalities" in the same environment, like Posix, UNIX, and a CORBA compliant distributed object architecture. Projects are being set-up to verify the suitability of our work for LHC applications, we are building a scaled-down prototype of the DAQ system foreseen for the CMS experiment at LHC, where we will directly test our protocols and where we will be able to make measurements and benchmarks, guiding our development and allowing us to build an analytical model of the system, suitable for simulation and large scale verification.

  2. Advanced Air Bag Technology Assessment

    NASA Technical Reports Server (NTRS)

    Phen, R. L.; Dowdy, M. W.; Ebbeler, D. H.; Kim. E.-H.; Moore, N. R.; VanZandt, T. R.

    1998-01-01

    As a result of the concern for the growing number of air-bag-induced injuries and fatalities, the administrators of the National Highway Traffic Safety Administration (NHTSA) and the National Aeronautics and Space Administration (NASA) agreed to a cooperative effort that "leverages NHTSA's expertise in motor vehicle safety restraint systems and biomechanics with NASAs position as one of the leaders in advanced technology development... to enable the state of air bag safety technology to advance at a faster pace..." They signed a NASA/NHTSA memorandum of understanding for NASA to "evaluate air bag to assess advanced air bag performance, establish the technological potential for improved technology (smart) air bag systems, and identify key expertise and technology within the agency (i.e., NASA) that can potentially contribute significantly to the improved effectiveness of air bags." NASA is committed to contributing to NHTSAs effort to: (1) understand and define critical parameters affecting air bag performance; (2) systematically assess air bag technology state of the art and its future potential; and (3) identify new concepts for air bag systems. The Jet Propulsion Laboratory (JPL) was selected by NASA to respond to the memorandum of understanding by conducting an advanced air bag technology assessment. JPL analyzed the nature of the need for occupant restraint, how air bags operate alone and with safety belts to provide restraint, and the potential hazards introduced by the technology. This analysis yielded a set of critical parameters for restraint systems. The researchers examined data on the performance of current air bag technology, and searched for and assessed how new technologies could reduce the hazards introduced by air bags while providing the restraint protection that is their primary purpose. The critical parameters which were derived are: (1) the crash severity; (2) the use of seat belts; (3) the physical characteristics of the occupants; (4) the

  3. Advanced Manufacturing Technologies (AMT): Additive Manufactured Hot Fire Planning and Testing in GRC Cell 32 Project

    NASA Technical Reports Server (NTRS)

    Fikes, John C.

    2014-01-01

    The objective of this project is to hot fire test an additively manufactured thrust chamber assembly TCA (injector and thrust chamber). GRC will install the additively manufactured Inconel 625 injector, two additively manufactured (SLM) water cooled Cu-Cr thrust chamber barrels and one additively manufactured (SLM) water cooled Cu-Cr thrust chamber nozzle on the test stand in Cell 32 and perform hot fire testing of the integrated TCA.

  4. Advanced Passivation Technology and Loss Factor Minimization for High Efficiency Solar Cells.

    PubMed

    Park, Cheolmin; Balaji, Nagarajan; Jung, Sungwook; Choi, Jaewoo; Ju, Minkyu; Lee, Seunghwan; Kim, Jungmo; Bong, Sungjae; Chung, Sungyoun; Lee, Youn-Jung; Yi, Junsin

    2015-10-01

    High-efficiency Si solar cells have attracted great attention from researchers, scientists, photovoltaic (PV) industry engineers for the past few decades. With thin wafers, surface passivation becomes necessary to increase the solar cells efficiency by overcoming several induced effects due to associated crystal defects and impurities of c-Si. This paper discusses suitable passivation schemes and optimization techniques to achieve high efficiency at low cost. SiNx film was optimized with higher transmittance and reduced recombination for using as an effective antireflection and passivation layer to attain higher solar cell efficiencies. The higher band gap increased the transmittance with reduced defect states that persisted at 1.68 and 1.80 eV in SiNx films. The thermal stability of SiN (Si-rich)/SiN (N-rich) stacks was also studied. Si-rich SiN with a refractive index of 2.7 was used as a passivation layer and N-rich SiN with a refractive index of 2.1 was used for thermal stability. An implied Voc of 720 mV with a stable lifetime of 1.5 ms was obtained for the stack layer after firing. Si-N and Si-H bonding concentration was analyzed by FTIR for the correlation of thermally stable passivation mechanism. The passivation property of spin coated Al2O3 films was also investigated. An effective surface recombination velocity of 55 cm/s with a high density of negative fixed charges (Qf) on the order of 9 x 10(11) cm(-2) was detected in Al2O3 films.

  5. Advancing Binaural Cochlear Implant Technology.

    PubMed

    Dietz, Mathias; McAlpine, David

    2015-12-30

    This special issue contains a collection of 13 papers highlighting the collaborative research and engineering project entitled Advancing Binaural Cochlear Implant Technology-ABCIT-as well as research spin-offs from the project. In this introductory editorial, a brief history of the project is provided, alongside an overview of the studies.

  6. Proton exchange membrane materials for the advancement of direct methanol fuel-cell technology

    DOEpatents

    Cornelius, Christopher J.

    2006-04-04

    A new class of hybrid organic-inorganic materials, and methods of synthesis, that can be used as a proton exchange membrane in a direct methanol fuel cell. In contrast with Nafion.RTM. PEM materials, which have random sulfonation, the new class of materials have ordered sulfonation achieved through self-assembly of alternating polyimide segments of different molecular weights comprising, for example, highly sulfonated hydrophilic PDA-DASA polyimide segment alternating with an unsulfonated hydrophobic 6FDA-DAS polyimide segment. An inorganic phase, e.g., 0.5 5 wt % TEOS, can be incorporated in the sulfonated polyimide copolymer to further improve its properties. The new materials exhibit reduced swelling when exposed to water, increased thermal stability, and decreased O.sub.2 and H.sub.2 gas permeability, while retaining proton conductivities similar to Nafion.RTM.. These improved properties may allow direct methanol fuel cells to operate at higher temperatures and with higher efficiencies due to reduced methanol crossover.

  7. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Gedney, Richard T.; Schertler, Ronald J.

    1989-01-01

    The NASA Advanced Communications Technology Satellite (ACTS) was conceived to help maintain U.S. leadership in the world's communications-satellite market. This experimental satellite is expected to be launched by NASA in 1992 and to furnish the technology necessary for establishing very small aperture terminal digital networks which provide on-demand full-mesh connectivity, and 1.544-MBPS services with only a single hop. Utilizing on-board switching and processing, each individual voice or data circuit can be separately routed to any location in the network. This paper provides an overview of the ACTS and discusses the value of the technology for future communications systems.

  8. Fuel cell technology program

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A fuel cell technology program was established to advance the state-of-the-art of hydrogen-oxygen fuel cells using low temperature, potassium hydroxide electrolyte technology as the base. Program tasks are described consisting of baseline cell design and stack testing, hydrogen pump design and testing, and DM-2 powerplant testing and technology extension efforts. A baseline cell configuration capable of a minimum of 2000 hours of life was defined. A 6-cell prototype stack, incorporating most of the scheme cell features, was tested for a total of 10,497 hours. A 6-cell stack incorporating all of the design features was tested. The DM-2 powerplant with a 34 cell stack, an accessory section packaged in the basic configuration anticipated for the space shuttle powerplant and a powerplant control unit, was defined, assembled, and tested. Cells were used in the stack and a drag-type hydrogen pump was installed in the accessory section. A test program was established, in conjunction with NASA/JSC, based on space shuttle orbiter mission. A 2000-hour minimum endurance test and a 5000-hour goal were set and the test started on August 8, 1972. The 2000-hour milestone was completed on November 3, 1972. On 13 March 1973, at the end of the thirty-first simulated seven-day mission and 5072 load hours, the test was concluded, all goals having been met. At this time, the DM-2 was in excellent condition and capable of additional endurance.

  9. NEMO: Advanced energy systems and technologies

    NASA Astrophysics Data System (ADS)

    Lund, P.

    In this report, the contents and major results of the national research program on advanced energy system and technologies (NEMO) are presented. The NEMO-program was one of the energy research programs of the Ministry of Trade and Industry during 1988-1992. Helsinki University of Technology had the responsibility of the overall coordination of the program. NEMO has been the largest resource allocation into advanced energy systems in Finland so far. The total budget was 70 million FIM. The focus of the program has been in solar energy, wind power, and energy storage. Hydrogen and fuel cells have been included in smaller amount. On all major fields of the NEMO-program, useful and high quality results have been obtained. Results of international significance include among others arctic wind energy, new approaches for the energy storage problem in solar energy applications, and the development of a completely new storage battery. International collaboration has been given high priority. The NEMO-program has also been active in informing the industries of the various business and utilization possibilities that advanced energy technologies offer. For example, major demonstration plants of each technology group have been realized. It is recommended that the further R and D should be still more focused on commercial applications. Through research efforts at universities, a good technology base should be maintained, whereas the industries should take a stronger position in commercializing new technology. Parallel to technology R and D, more public resources should be allocated for market introduction.

  10. Subsea completion technology needs advances

    SciTech Connect

    Ledbetter, R.

    1995-09-18

    Subsea technology needs further advances to reduce operational costs before operators will expand the use of subsea well completions in the Gulf of Mexico. They will continue to choose surface completion-oriented systems as long as these are more economical operationally than subsea system. Designs of subsea equipment such as trees, connectors, control pods, umbilicals, and flow lines, must bring about reductions in the cost of both installation and workover compatibility. Remote operated vehicle (ROV) manipulation is one avenue that should be exploited. The bottom line is that significant cooperation between equipment manufacturers and ROV companies is needed to develop advanced ROV technology, and operators should be involved to help guide operational strategies.

  11. Live-cell analysis of plant reproduction: live-cell imaging, optical manipulation, and advanced microscopy technologies.

    PubMed

    Kurihara, Daisuke; Hamamura, Yuki; Higashiyama, Tetsuya

    2013-05-01

    Sexual reproduction ensures propagation of species and enhances genetic diversity within populations. In flowering plants, sexual reproduction requires complicated and multi-step cell-to-cell communications among male and female cells. However, the confined nature of plant reproduction processes, which occur in the female reproductive organs and several cell layers of the pistil, limits our ability to observe these events in vivo. In this review, we discuss recent live-cell imaging in in vitro systems and the optical manipulation techniques that are used to capture the dynamic mechanisms representing molecular and cellular communications in sexual plant reproduction. PMID:23438900

  12. Live-cell analysis of plant reproduction: live-cell imaging, optical manipulation, and advanced microscopy technologies.

    PubMed

    Kurihara, Daisuke; Hamamura, Yuki; Higashiyama, Tetsuya

    2013-05-01

    Sexual reproduction ensures propagation of species and enhances genetic diversity within populations. In flowering plants, sexual reproduction requires complicated and multi-step cell-to-cell communications among male and female cells. However, the confined nature of plant reproduction processes, which occur in the female reproductive organs and several cell layers of the pistil, limits our ability to observe these events in vivo. In this review, we discuss recent live-cell imaging in in vitro systems and the optical manipulation techniques that are used to capture the dynamic mechanisms representing molecular and cellular communications in sexual plant reproduction.

  13. Center for Advanced Computational Technology

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.

    2000-01-01

    The Center for Advanced Computational Technology (ACT) was established to serve as a focal point for diverse research activities pertaining to application of advanced computational technology to future aerospace systems. These activities include the use of numerical simulations, artificial intelligence methods, multimedia and synthetic environments, and computational intelligence, in the modeling, analysis, sensitivity studies, optimization, design and operation of future aerospace systems. The Center is located at NASA Langley and is an integral part of the School of Engineering and Applied Science of the University of Virginia. The Center has four specific objectives: 1) conduct innovative research on applications of advanced computational technology to aerospace systems; 2) act as pathfinder by demonstrating to the research community what can be done (high-potential, high-risk research); 3) help in identifying future directions of research in support of the aeronautical and space missions of the twenty-first century; and 4) help in the rapid transfer of research results to industry and in broadening awareness among researchers and engineers of the state-of-the-art in applications of advanced computational technology to the analysis, design prototyping and operations of aerospace and other high-performance engineering systems. In addition to research, Center activities include helping in the planning and coordination of the activities of a multi-center team of NASA and JPL researchers who are developing an intelligent synthesis environment for future aerospace systems; organizing workshops and national symposia; as well as writing state-of-the-art monographs and NASA special publications on timely topics.

  14. Fuel cell technology program

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A program to advance the technology for a cost-effective hydrogen/oxygen fuel cell system for future manned spacecraft is discussed. The evaluation of base line design concepts and the development of product improvements in the areas of life, power, specific weight and volume, versatility of operation, field maintenance and thermal control were conducted from the material and component level through the fabrication and test of an engineering model of the fuel cell system. The program was to be accomplished in a 13 month period.

  15. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Plecity, Mark S.; Nall, Mark E.

    1991-01-01

    The NASA Advanced Communications Technology Satellite (ACTS) provides high risk technologies having the potential to dramatically enhance the capabilities of the satellite communications industry. This experimental satellite, which will be launched by NASA in 1993, will furnish the technology necessary for providing a range of services. Utilizing the ACTS very-high-gain-hopping spot-beam antennas with on-board routing and processing, Very Small Aperture Terminal (VSAT) digital networks which provide on-demand, full-mesh-convectivity 1.544-MBPS services with only a single hop can be established. The high-gain spot-beam antenna at Ka-band permits wide area, flexible networks providing high data rate services between modest-size earth terminals.

  16. Advances in single chain technology.

    PubMed

    Gonzalez-Burgos, Marina; Latorre-Sanchez, Alejandro; Pomposo, José A

    2015-10-01

    The recent ability to manipulate and visualize single atoms at atomic level has given rise to modern bottom-up nanotechnology. Similar exquisite degree of control at the individual polymeric chain level for producing functional soft nanoentities is expected to become a reality in the next few years through the full development of so-called "single chain technology". Ultra-small unimolecular soft nano-objects endowed with useful, autonomous and smart functions are the expected, long-term valuable output of single chain technology. This review covers the recent advances in single chain technology for the construction of soft nano-objects via chain compaction, with an emphasis in dynamic, letter-shaped and compositionally unsymmetrical single rings, complex multi-ring systems, single chain nanoparticles, tadpoles, dumbbells and hairpins, as well as the potential end-use applications of individual soft nano-objects endowed with useful functions in catalysis, sensing, drug delivery and other uses. PMID:26505056

  17. Advances in single chain technology.

    PubMed

    Gonzalez-Burgos, Marina; Latorre-Sanchez, Alejandro; Pomposo, José A

    2015-10-01

    The recent ability to manipulate and visualize single atoms at atomic level has given rise to modern bottom-up nanotechnology. Similar exquisite degree of control at the individual polymeric chain level for producing functional soft nanoentities is expected to become a reality in the next few years through the full development of so-called "single chain technology". Ultra-small unimolecular soft nano-objects endowed with useful, autonomous and smart functions are the expected, long-term valuable output of single chain technology. This review covers the recent advances in single chain technology for the construction of soft nano-objects via chain compaction, with an emphasis in dynamic, letter-shaped and compositionally unsymmetrical single rings, complex multi-ring systems, single chain nanoparticles, tadpoles, dumbbells and hairpins, as well as the potential end-use applications of individual soft nano-objects endowed with useful functions in catalysis, sensing, drug delivery and other uses.

  18. Electrochemical carbon dioxide concentrator advanced technology tasks

    NASA Technical Reports Server (NTRS)

    Schneider, J. J.; Schubert, F. H.; Hallick, T. M.; Woods, R. R.

    1975-01-01

    Technology advancement studies are reported on the basic electrochemical CO2 removal process to provide a basis for the design of the next generation cell, module and subsystem hardware. An Advanced Electrochemical Depolarized Concentrator Module (AEDCM) is developed that has the characteristics of low weight, low volume, high CO2, removal, good electrical performance and low process air pressure drop. Component weight and noise reduction for the hardware of a six man capacity CO2 collection subsystem was developed for the air revitalization group of the Space Station Prototype (SSP).

  19. Center for Advanced Separation Technology

    SciTech Connect

    Honaker, Rick

    2013-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, CAST is now a five-university consortium – Virginia Tech, West Virginia University, University of Kentucky, University of Utah and Montana Tech, - that is supported through U.S. DOE Cooperative Agreement No. DE-FE0000699, Center for Advanced Separation Technology. Much of the research to be conducted with Cooperative Agreement funds will be longer term, high-risk, basic research and will be carried out in two broad areas: Advanced Pre-Combustion Clean Coal Technologies and Gas-Gas Separations. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the five member universities. These were reviewed and the selected proposals were forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed below by category, along with abstracts from their final reports.

  20. Advances in SIS receiver technology

    NASA Technical Reports Server (NTRS)

    Frerking, M. A.

    1988-01-01

    Significant advances in SIS receiver technology since the last Asilomar meeting include: superconductor materials, integrated inductive tuning elements, and planar mounting structures. The effect of these advances is to push the upper frequency operating limit from about 600 to 1500 GHz, and to enhance the feasibility of focal plane arrays of heterodyne receivers. A fundamental high frequency operating limit of SIS mixers is set by the superconducting energy gap. A practical limitation for high frequency operation of SIS junctions is their parasitic capacitance and resistance. The performance of the mixer will be degraded by the Resistor-Capacitor rolloff. Several designs were reported for inductive elements integrated on the same substrate as the SIS junctions to tune out the bulk junction capacitance. Most millimeter SIS-based heterodyne receivers have used waveguide coupling structures. Technology has advanced to the state where programs that have a high probability of success can be defined to produce arrays of SIS receivers for frequencies as high as 1500 GHz.

  1. Advances in Genome Biology & Technology

    SciTech Connect

    Thomas J. Albert, Jon R. Armstrong, Raymond K. Auerback, W. Brad Barbazuk, et al.

    2007-12-01

    This year's meeting focused on the latest advances in new DNA sequencing technologies and the applications of genomics to disease areas in biology and biomedicine. Daytime plenary sessions highlighted cutting-edge research in areas such as complex genetic diseases, comparative genomics, medical sequencing, massively parallel DNA sequencing, and synthetic biology. Technical approaches being developed and utilized in contemporary genomics research were presented during evening concurrent sessions. Also, as in previous years, poster sessions bridged the morning and afternoon plenary sessions. In addition, for the third year in a row, the Advances in Genome Biology and Technology (AGBT) meeting was preceded by a pre-meeting workshop that aimed to provide an introductory overview for trainees and other meeting attendees. This year, speakers at the workshop focused on next-generation sequencing technologies, including their experiences, findings, and helpful advise for others contemplating using these platforms in their research. Speakers from genome centers and core sequencing facilities were featured and the workshop ended with a roundtable discussion, during which speakers fielded questions from the audience.

  2. [Advances in genetic modification technologies].

    PubMed

    Zhang, Baixue; Sun, Qixin; Li, Haifeng

    2015-08-01

    Genetic modification technology is a new molecular tool for targeted genome modification. It includes zinc finger nucleases (ZFN) technology, transcription activator-like effector nucleases (TALEN) technology and clustered regularly interspaced short palindromic repeat (CRISPR)-associated (Cas) (CRISPR-Cas) nucleases technology. All of these nucleases create DNA double-strand breaks (DSB) at chromosomal targeted sites and induce cell endogenous mechanisms that are primarily repaired by the non-homologous end joining (NHEJ) or homologous recombination (HR) pathway, resulting in targeted endogenous gene knock-out or exogenous gene insertion. In recent years, genetic modification technologies have been successfully applied to bacteria, yeast, human cells, fruit fly, zebra fish, mouse, rat, livestock, cynomolgus monkey, Arabidopsis, rice, tobacco, maize, sorghum, wheat, barley and other organisms, showing its enormous advantage in gene editing field. Especially, the newly developed CRISPR-Cas9 system arose more attention because of its low cost, high effectiveness, simplicity and easiness. We reviewed the principles and the latest research progress of these three technologies, as well as prospect of future research and applications.

  3. Advances in nondestructive evaluation technology

    NASA Technical Reports Server (NTRS)

    Heyman, J. S.

    1982-01-01

    Research at NASA Langley's Materials Characterization Instrumentation Section has followed the philosophy of improving the science base of nondestructive evaluation and advancing the state of the art of quantitative interpretability of physical measurements of materials. Details of several R&D programs choosen to highlight the last several years are given. Applications of these technologies are presented in the area of stress measurement, characterization of metal heat treatment, and evaluation of material internal structure. A second focus of the program is on quantitative transducers/measurements that have resulted in better data in irregular inhomogeneous materials such as composites. Examples are presented of new capabilities resulting from these advances that include fatigue and impact damage evaluation.

  4. [Technological advances: the coming radiology].

    PubMed

    García, César; Ortega, Dulia

    2002-06-01

    We are living in a changing world, acknowledging all kinds of changes: social, technological, and ethical. This is the environment encircling medical and radiological work: demanding, with high expectations and a cohort of amazing technological advances, in all areas of human knowledge. We need to make the necessary reflections about these faster and faster changes. Radiology, as an important part of clinical work, is facing no minor challenges: technological and other most prevalent like: Who will be specialists in the next future? How are we prepared to face the radiological teaching and formation of radiologists? How to finance this technological developments? Meanwhile, in our context of an underdeveloped country, this sounds as far as the Moon, but changes will reach us sooner or later. We must resolve some problems that are a little bit more basic, such as a good level of education and health care for our people, then we will be ready to incorporate some of these amazing new technologies. PMID:12194695

  5. Materials Advance Chemical Propulsion Technology

    NASA Technical Reports Server (NTRS)

    2012-01-01

    In the future, the Planetary Science Division of NASA's Science Mission Directorate hopes to use better-performing and lower-cost propulsion systems to send rovers, probes, and observers to places like Mars, Jupiter, and Saturn. For such purposes, a new propulsion technology called the Advanced Materials Bipropellant Rocket (AMBR) was developed under NASA's In-Space Propulsion Technology (ISPT) project, located at Glenn Research Center. As an advanced chemical propulsion system, AMBR uses nitrogen tetroxide oxidizer and hydrazine fuel to propel a spacecraft. Based on current research and development efforts, the technology shows great promise for increasing engine operation and engine lifespan, as well as lowering manufacturing costs. In developing AMBR, ISPT has several goals: to decrease the time it takes for a spacecraft to travel to its destination, reduce the cost of making the propulsion system, and lessen the weight of the propulsion system. If goals like these are met, it could result in greater capabilities for in-space science investigations. For example, if the amount (and weight) of propellant required on a spacecraft is reduced, more scientific instruments (and weight) could be added to the spacecraft. To achieve AMBR s maximum potential performance, the engine needed to be capable of operating at extremely high temperatures and pressure. To this end, ISPT required engine chambers made of iridium-coated rhenium (strong, high-temperature metallic elements) that allowed operation at temperatures close to 4,000 F. In addition, ISPT needed an advanced manufacturing technique for better coating methods to increase the strength of the engine chamber without increasing the costs of fabricating the chamber.

  6. Advances in traction drive technology

    NASA Technical Reports Server (NTRS)

    Loewenthal, S. H.; Anderson, N. E.; Rohn, D. A.

    1983-01-01

    Traction drives are traced from early uses as main transmissions in automobiles at the turn of the century to modern, high-powered traction drives capable of transmitting hundreds of horsepower. Recent advances in technology are described which enable today's traction drive to be a serious candidate for off-highway vehicles and helicopter applications. Improvements in materials, traction fluids, design techniques, power loss and life prediction methods will be highlighted. Performance characteristics of the Nasvytis fixed-ratio drive are given. Promising future drive applications, such as helicopter main transmissions and servo-control positioning mechanisms are also addressed.

  7. Advanced Artificial Intelligence Technology Testbed

    NASA Technical Reports Server (NTRS)

    Anken, Craig S.

    1993-01-01

    The Advanced Artificial Intelligence Technology Testbed (AAITT) is a laboratory testbed for the design, analysis, integration, evaluation, and exercising of large-scale, complex, software systems, composed of both knowledge-based and conventional components. The AAITT assists its users in the following ways: configuring various problem-solving application suites; observing and measuring the behavior of these applications and the interactions between their constituent modules; gathering and analyzing statistics about the occurrence of key events; and flexibly and quickly altering the interaction of modules within the applications for further study.

  8. Advanced Mirror & Modelling Technology Development

    NASA Technical Reports Server (NTRS)

    Effinger, Michael; Stahl, H. Philip; Abplanalp, Laura; Maffett, Steven; Egerman, Robert; Eng, Ron; Arnold, William; Mosier, Gary; Blaurock, Carl

    2014-01-01

    The 2020 Decadal technology survey is starting in 2018. Technology on the shelf at that time will help guide selection to future low risk and low cost missions. The Advanced Mirror Technology Development (AMTD) team has identified development priorities based on science goals and engineering requirements for Ultraviolet Optical near-Infrared (UVOIR) missions in order to contribute to the selection process. One key development identified was lightweight mirror fabrication and testing. A monolithic, stacked, deep core mirror was fused and replicated twice to achieve the desired radius of curvature. It was subsequently successfully polished and tested. A recently awarded second phase to the AMTD project will develop larger mirrors to demonstrate the lateral scaling of the deep core mirror technology. Another key development was rapid modeling for the mirror. One model focused on generating optical and structural model results in minutes instead of months. Many variables could be accounted for regarding the core, face plate and back structure details. A portion of a spacecraft model was also developed. The spacecraft model incorporated direct integration to transform optical path difference to Point Spread Function (PSF) and between PSF to modulation transfer function. The second phase to the project will take the results of the rapid mirror modeler and integrate them into the rapid spacecraft modeler.

  9. Advanced microfabrication technologies for microspacecraft

    NASA Astrophysics Data System (ADS)

    Ghezzo, M.; Bagepalli, B.; Kodiyalam, S.; Korham, C.; Browall, K.; Alexander, Norman

    1993-06-01

    Advanced microfabrication technologies offer the prospect of reducing the weight and size of spacecraft through the use of lighter and stronger materials in conjunction with new mechanical/structural design concepts and design optimization methods. At the same time, electronic components have been scaled down while increasing functional utility. A two-fold benefit is derived for space applications through the use of less expensive components and the lower launch costs associated with lighter components. GE-CRD is actively pursuing research in these key technologies for a wide range of applications including satellites. These key technologies will be reviewed and an update on GE progress will be given. The need to reduce weight and lower cost, while maintaining product quality and reliability are primary drivers in the design of satellites, in general, and microsatellites in particular. For the structural subsystem, these requirements pose a complex design problem unless new mechanical design concepts and computer-aided design optimization methods are employed. Several new concepts, such as battery packs doubling as panel reinforcements and fuel tanks as integral structural members, need to utilized. In addition, new viscoelastic material damping concepts for spacecraft components provide for lighter weight/lower cost designs, while satisfying the structural dynamics requirements. High density interconnect (HDI) technology permits the use of bare IC's on a ceramic substrate with 90 percent active area utilization. A copper/polyimide multilayer structure is the backbone of the technology, which has demonstrated a size/weight reduction of greater than 10x compared to printed circuit board with performance up to the GHz level. HDI modules have exceptional mechanical robustness as evidenced by survival of 180 kg rapid acceleration tests. Microelectromechanical systems (MEMS) are redefining sensors and actuators by miniaturization through micromachining techniques

  10. ARPA advanced fuel cell development

    SciTech Connect

    Dubois, L.H.

    1995-08-01

    Fuel cell technology is currently being developed at the Advanced Research Projects Agency (ARPA) for several Department of Defense applications where its inherent advantages such as environmental compatibility, high efficiency, and low noise and vibration are overwhelmingly important. These applications range from man-portable power systems of only a few watts output (e.g., for microclimate cooling and as direct battery replacements) to multimegawatt fixed base systems. The ultimate goal of the ARPA program is to develop an efficient, low-temperature fuel cell power system that operates directly on a military logistics fuel (e.g., DF-2 or JP-8). The absence of a fuel reformer will reduce the size, weight, cost, and complexity of such a unit as well as increase its reliability. In order to reach this goal, ARPA is taking a two-fold, intermediate time-frame approach to: (1) develop a viable, low-temperature proton exchange membrane (PEM) fuel cell that operates directly on a simple hydrocarbon fuel (e.g., methanol or trimethoxymethane) and (2) demonstrate a thermally integrated fuel processor/fuel cell power system operating on a military logistics fuel. This latter program involves solid oxide (SOFC), molten carbonate (MCFC), and phosphoric acid (PAFC) fuel cell technologies and concentrates on the development of efficient fuel processors, impurity scrubbers, and systems integration. A complementary program to develop high performance, light weight H{sub 2}/air PEM and SOFC fuel cell stacks is also underway. Several recent successes of these programs will be highlighted.

  11. Genome engineering in cattle: recent technological advancements.

    PubMed

    Wang, Zhongde

    2015-02-01

    Great strides in technological advancements have been made in the past decade in cattle genome engineering. First, the success of cloning cattle by somatic cell nuclear transfer (SCNT) or chromatin transfer (CT) is a significant advancement that has made obsolete the need for using embryonic stem (ES) cells to conduct cell-mediated genome engineering, whereby site-specific genetic modifications can be conducted in bovine somatic cells via DNA homologous recombination (HR) and whereby genetically engineered cattle can subsequently be produced by animal cloning from the genetically modified cells. With this approach, a chosen bovine genomic locus can be precisely modified in somatic cells, such as to knock out (KO) or knock in (KI) a gene via HR, a gene-targeting strategy that had almost exclusively been used in mouse ES cells. Furthermore, by the creative application of embryonic cloning to rejuvenate somatic cells, cattle genome can be sequentially modified in the same line of somatic cells and complex genetic modifications have been achieved in cattle. Very recently, the development of designer nucleases-such as zinc finger nucleases (ZFNs) and transcription activator-like effector nuclease (TALENs), and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9)-has enabled highly efficient and more facile genome engineering in cattle. Most notably, by employing such designer nucleases, genomes can be engineered at single-nucleotide precision; this process is now often referred to as genome or gene editing. The above achievements are a drastic departure from the traditional methods of creating genetically modified cattle, where foreign DNAs are randomly integrated into the animal genome, most often along with the integrations of bacterial or viral DNAs. Here, I review the most recent technological developments in cattle genome engineering by highlighting some of the major achievements in creating genetically engineered

  12. Important advances in technology: echocardiography.

    PubMed

    Nagueh, Sherif F; Quiñones, Miguel A

    2014-01-01

    Echocardiography has evolved over the past 45 years from a simple M-mode tracing to an array of technologies that include two-dimensional imaging, pulsed and continuous wave spectral Doppler, color flow and tissue Doppler, and transesophageal echocardiography. Together, these modalities provide a comprehensive anatomic and functional evaluation of cardiac chambers and valves, pericardium, and ascending and descending aorta. The switch from analog to digital signal processing revolutionized the field of ultrasound, resulting in improved image resolution, smaller instrumentation that allows bedside evaluation and diagnosis of patients, and digital image storage for more accurate quantification and comparison with previous studies. It also opened the door for new advances such as harmonic imaging, automated border detection and quantification, 3-dimensional imaging, and speckle tracking. This article offers an overview of some newer developments in echocardiography and their promising applications.

  13. Advanced Technology Composite Fuselage - Manufacturing

    NASA Technical Reports Server (NTRS)

    Wilden, K. S.; Harris, C. G.; Flynn, B. W.; Gessel, M. G.; Scholz, D. B.; Stawski, S.; Winston, V.

    1997-01-01

    The goal of Boeing's Advanced Technology Composite Aircraft Structures (ATCAS) program is to develop the technology required for cost-and weight-efficient use of composite materials in transport fuselage structure. Carbon fiber reinforced epoxy was chosen for fuselage skins and stiffening elements, and for passenger and cargo floor structures. The automated fiber placement (AFP) process was selected for fabrication of stringer-stiffened and sandwich skin panels. Circumferential and window frames were braided and resin transfer molded (RTM'd). Pultrusion was selected for fabrication of floor beams and constant-section stiffening elements. Drape forming was chosen for stringers and other stiffening elements cocured to skin structures. Significant process development efforts included AFP, braiding, RTM, autoclave cure, and core blanket fabrication for both sandwich and stiffened-skin structure. Outer-mold-line and inner-mold-line tooling was developed for sandwich structures and stiffened-skin structure. The effect of design details, process control and tool design on repeatable, dimensionally stable, structure for low cost barrel assembly was assessed. Subcomponent panels representative of crown, keel, and side quadrant panels were fabricated to assess scale-up effects and manufacturing anomalies for full-scale structures. Manufacturing database including time studies, part quality, and manufacturing plans were generated to support the development of designs and analytical models to access cost, structural performance, and dimensional tolerance.

  14. Advances in nanopore sequencing technology.

    PubMed

    Yang, Yongqiang; Liu, Ruoyu; Xie, Haiqiang; Hui, Yanting; Jiao, Rengang; Gong, Yu; Zhang, Yiyu

    2013-07-01

    Much tremendous break through have been obtained in recent years for nanopore sequencing to achieve the goal of $1000 genome. As a method of single molecule sequencing, nanopore sequencing can discriminate the individual molecules of the target DNA strand rapidly due to the current blockages by translocating the nucleotides through a nano-scale pore. Both the protein-pores and solid-state nanopore channels which called single nanopore sequencing have been studied widely for the application of nanopore sequencing technology. This review will give a detail representation to protein nanopore and solid-state nanopore sequencing. For protein nanopore sequencing technology, we will introduce different nanopore types, device assembly and some challenges still exist at present. We will focus on more research fields for solid-state nanopore sequencing in terms of materials, device assembly, fabricated methods, translocation process and some specific challenges. The review also covers some of the technical advances in the union nanopore sequencing, which include nanopore sequencing combine with exonuclease, hybridization, synthesis and design polymer.

  15. ADVANCED RECIPROCATING COMPRESSION TECHNOLOGY (ARCT)

    SciTech Connect

    Danny M. Deffenbaugh; Klaus Brun; Ralph E. Harris; J. Pete Harrell; Robert J. Mckee; J. Jeffrey Moore; Steven J. Svedeman; Anthony J. Smalley; Eugene L. Broerman; Robert A Hart; Marybeth G. Nored; Ryan S. Gernentz; Shane P. Siebenaler

    2005-12-01

    The U.S. natural gas pipeline industry is facing the twin challenges of increased flexibility and capacity expansion. To meet these challenges, the industry requires improved choices in gas compression to address new construction and enhancement of the currently installed infrastructure. The current fleet of installed reciprocating compression is primarily slow-speed integral machines. Most new reciprocating compression is and will be large, high-speed separable units. The major challenges with the fleet of slow-speed integral machines are: limited flexibility and a large range in performance. In an attempt to increase flexibility, many operators are choosing to single-act cylinders, which are causing reduced reliability and integrity. While the best performing units in the fleet exhibit thermal efficiencies between 90% and 92%, the low performers are running down to 50% with the mean at about 80%. The major cause for this large disparity is due to installation losses in the pulsation control system. In the better performers, the losses are about evenly split between installation losses and valve losses. The major challenges for high-speed machines are: cylinder nozzle pulsations, mechanical vibrations due to cylinder stretch, short valve life, and low thermal performance. To shift nozzle pulsation to higher orders, nozzles are shortened, and to dampen the amplitudes, orifices are added. The shortened nozzles result in mechanical coupling with the cylinder, thereby, causing increased vibration due to the cylinder stretch mode. Valve life is even shorter than for slow speeds and can be on the order of a few months. The thermal efficiency is 10% to 15% lower than slow-speed equipment with the best performance in the 75% to 80% range. The goal of this advanced reciprocating compression program is to develop the technology for both high speed and low speed compression that will expand unit flexibility, increase thermal efficiency, and increase reliability and integrity

  16. Modern Imaging Technology: Recent Advances

    SciTech Connect

    Welch, Michael J.; Eckelman, William C.

    2004-06-18

    This 2-day conference is designed to bring scientist working in nuclear medicine, as well as nuclear medicine practitioners together to discuss the advances in four selected areas of imaging: Biochemical Parameters using Small Animal Imaging, Developments in Small Animal PET Imaging, Cell Labeling, and Imaging Angiogenesis Using Multiple Modality. The presentations will be on molecular imaging applications at the forefront of research, up to date on the status of molecular imaging in nuclear medicine as well as in related imaging areas. Experts will discuss the basic science of imaging techniques, and scheduled participants will engage in an exciting program that emphasizes the current status of molecular imaging as well as the role of DOE funded research in this area.

  17. Advanced Training Technologies and Learning Environments

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

    1999-01-01

    This document contains the proceedings of the Workshop on Advanced Training Technologies and Learning Environments held at NASA Langley Research Center, Hampton, Virginia, March 9-10, 1999. The workshop was jointly sponsored by the University of Virginia's Center for Advanced Computational Technology and NASA. Workshop attendees were from NASA, other government agencies, industry, and universities. The objective of the workshop was to assess the status and effectiveness of different advanced training technologies and learning environments.

  18. Micromachining technology for advanced weapon systems

    SciTech Connect

    Sniegowski, J.J.

    1996-12-31

    An overview of planned uses for polysilicon surface-micromachining technology in advanced weapon systems is presented. Specifically, this technology may allow consideration of fundamentally new architectures for realization of surety component functions.

  19. Recent advances in flue gas desulfurization technologies

    SciTech Connect

    Pan, Y.S.

    1991-01-01

    Recent advances in flue gas desulfurization (FGD) technologies are reported. The technological advances include conventional wet FGD system improvements, advanced wet FGD system development, spray dryer system operations, technologies for furnace sorbent injections, post-combustion dry technologies, combined SO{sub 2}/NO{sub x} technologies, and several emerging FGD technologies. In addition, progress of by-product utilization that affects the operating cost of FGD systems is described. Economics of some commercially available and nearly maturing FGD technologies is also discussed. The materials included in this report are obtained from technical presentations made through September 1990, at several national and international conferences. This report is intended to document current advances and status of various FGD technologies. 101 refs., 16 figs.

  20. COSTS FOR ADVANCED COAL COMBUSTION TECHNOLOGIES

    EPA Science Inventory

    The report gives results of an evaluation of the development status of advanced coal combustion technologies and discusses the preparation of performance and economic models for their application to electric utility plants. he technologies addressed were atmospheric fluidized bed...

  1. Advancing colloidal quantum dot photovoltaic technology

    NASA Astrophysics Data System (ADS)

    Cheng, Yan; Arinze, Ebuka S.; Palmquist, Nathan; Thon, Susanna M.

    2016-06-01

    Colloidal quantum dots (CQDs) are attractive materials for solar cells due to their low cost, ease of fabrication and spectral tunability. Progress in CQD photovoltaic technology over the past decade has resulted in power conversion efficiencies approaching 10%. In this review, we give an overview of this progress, and discuss limiting mechanisms and paths for future improvement in CQD solar cell technology.We briefly summarize nanoparticle synthesis and film processing methods and evaluate the optoelectronic properties of CQD films, including the crucial role that surface ligands play in materials performance. We give an overview of device architecture engineering in CQD solar cells. The compromise between carrier extraction and photon absorption in CQD photovoltaics is analyzed along with different strategies for overcoming this trade-off. We then focus on recent advances in absorption enhancement through innovative device design and the use of nanophotonics. Several light-trapping schemes, which have resulted in large increases in cell photocurrent, are described in detail. In particular, integrating plasmonic elements into CQD devices has emerged as a promising approach to enhance photon absorption through both near-field coupling and far-field scattering effects. We also discuss strategies for overcoming the single junction efficiency limits in CQD solar cells, including tandem architectures, multiple exciton generation and hybrid materials schemes. Finally, we offer a perspective on future directions for the field and the most promising paths for achieving higher device efficiencies.

  2. Advanced cell technology for high performance Li-A1/FeS{sub 2} secondary batteries.

    SciTech Connect

    Henriksen, G. L.

    1998-07-10

    In early 1993. Argonne National Laboratory (ANL) initiated a major R and D effort to develop bipolar Li-Al/LiCl-LiBr-KBr/FeS{sub 2} batteries for electric vehicles, targeting the USABC Long-Term Goals. Significant advancements were achieved in the areas of (i) chemical purity, (ii) electrode and electrolyte additives, and (iii) peripheral seals. It was determined that key chemical constituents contained undesirable impurities. ANL developed new chemical processes for preparing Li{sub 2}S, FeS, and CoS{sub 2} that were >98.5% pure. We evaluated a large variety of electrode and electrolyte additives for reducing cell area specific impedance (ASI). Candidate positive electrode additives offered increased electronic conductivity, enhanced reaction kinetics, and/or improved porous electrode morphology. CoS{sub 2}, CuFeS{sub 2}, MgO, and graphite (fibers) were identified as the most beneficial impedance-reducing positive electrode additives. Although electronically conductive carbon and graphite additives produced measurable ASI reductions in the negative electrode, they degraded its structural integrity and were deemed impractical. Lil and LiF were identified as beneficial electrolyte additives, that enhance positive electrode kinetics. ANL refined its baseline metal/ceramic peripheral seal and increased its strength by a factor of three (achieving a safety factor >10). In parallel, ANL developed a high-strength advanced metal/ceramic seal that offers appreciable cost reductions.

  3. Development of advanced fuel cell system

    NASA Technical Reports Server (NTRS)

    Gitlow, B.; Meyer, A. P.; Bell, W. F.; Martin, R. E.

    1978-01-01

    An experimental program was conducted continuing the development effort to improve the weight, life, and performance characteristics of hydrogen-oxygen alkaline fuel cells for advanced power systems. These advanced technology cells operate with passive water removal which contributes to a lower system weight and extended operating life. Endurance evaluation of two single cells and two, two-cell plaques was continued. Three new test articles were fabricated and tested. A single cell completed 7038 hours of endurance testing. This cell incorporated a Fybex matrix, hybrid-frame, PPF anode, and a 90 Au/10 Pt cathode. This configuration was developed to extend cell life. Two cell plaques with dedicated flow fields and manifolds for all fluids did not exhibit the cell-to-cell electrolyte transfer that limited the operating life of earlier multicell plaques.

  4. Technological advances in powered wheelchairs.

    PubMed

    Edlich, Richard F; Nelson, Kenneth P; Foley, Marni L; Buschbacher, Ralph M; Long, William B; Ma, Eva K

    2004-01-01

    During the last 40 years, there have been revolutionary advances in power wheelchairs. These unique wheelchair systems, designed for the physically immobile patient, have become extremely diversified, allowing the user to achieve different positions, including tilt, recline, and, more recently, passive standing. Because of this wide diversity of powered wheelchair products, there is a growing realization of the need for certification of wheeled mobility suppliers. Legislation in Tennessee (Consumer Protection Act for Wheeled Mobility) passed in 2003 will ensure that wheeled mobility suppliers must have Assistive Technology Supplier certification and maintain their continuing education credits when fitting individuals in wheelchairs for long-term use. Fifteen other legislative efforts are currently underway in general assemblies throughout the US. Manufacturers, dealers, hospitals, and legislators are working toward the ultimate goal of passing federal legislation delineating the certification process of wheeled mobility suppliers. The most recent advance in the design of powered wheelchairs is the development of passive standing positions. The beneficial effects of passive standing have been documented by comprehensive scientific studies. These benefits include reduction of seating pressure, decreased bone demineralization, increased bladder pressure, enhanced orthostatic circulatory regulation, reduction in muscular tone, decrease in upper extremity muscle stress, and enhanced functional status in general. In February 2003, Permobil, Inc., introduced the powered Permobil Chairman 2K Stander wheelchair, which can tilt, recline, and stand. Other companies are now manufacturing powered wheelchairs that can achieve a passive standing position. These wheelchairs include the Chief SR Powerchair, VERTRAN, and LifeStand Compact. Another new addition to the wheelchair industry is the iBOT, which can elevate the user to reach cupboards and climb stairs but has no passive

  5. [Results of complex treatment of patients with squamous cell carcinoma of the anal canal using advanced radiotherapy technologies].

    PubMed

    Glebovskaya, V V; Tkachev, S I; Rasulov, A O; Tsaryuk, V F; Gordeev, S S; Fedyanin, M Yu; Aliev, V A; Mamedly, Z Z; Kuzmichev, D V; Trofimova, O P; Borisova, T N; Yazhgunovich, I P

    2015-01-01

    During recent decades radiotherapy is the basis, on which it is built a medical complex that is the first-line treatment of patients with squamous cell carcinoma of the anal canal. An increase of overall and disease-free survival and quality of life of patients with squamous cell carcinoma of the anal canal at the present stage of development of a comprehensive medical treatment is largely due to the improvement of technical equipment of radiotherapy departments of oncology clinics. The use of modem linear electron accelerators and systems of computer dosimetric planning to create a 3D program of isodose distribution, diagnostic devices (computed tomography and magnetic resonance imaging) as well as a number of other conditions permit accurate summarizing of proposed dose, reducing of absorbed dose to critical structures, diminishing unplanned interruptions in chemoradiotherapy course by means of modern technologies of conformal radiotherapy (3D CRT, IMRT, VMAT). The paper presents the preliminary results of a comprehensive medical treatment of 14 patients with squamous cell carcinoma of the anal canal. PMID:26571840

  6. Advancements in Aptamer Discovery Technologies.

    PubMed

    Gotrik, Michael R; Feagin, Trevor A; Csordas, Andrew T; Nakamoto, Margaret A; Soh, H Tom

    2016-09-20

    transforms solution-phase aptamers into "aptamer particles" that can be individually screened at high-throughput via fluorescence-activated cell sorting. Using PD, we have shown the feasibility of rapidly generating aptamers with exceptional affinities, even for proteins that have previously proven intractable to aptamer discovery. We are confident that these advanced aptamer-discovery methods will accelerate the discovery of aptamer reagents with excellent affinities and specificities, perhaps even exceeding those of the best monoclonal antibodies. Since aptamers are reproducible, renewable, stable, and can be distributed as sequence information, we anticipate that these affinity reagents will become even more valuable tools for both research and clinical applications.

  7. Advancements in Aptamer Discovery Technologies.

    PubMed

    Gotrik, Michael R; Feagin, Trevor A; Csordas, Andrew T; Nakamoto, Margaret A; Soh, H Tom

    2016-09-20

    transforms solution-phase aptamers into "aptamer particles" that can be individually screened at high-throughput via fluorescence-activated cell sorting. Using PD, we have shown the feasibility of rapidly generating aptamers with exceptional affinities, even for proteins that have previously proven intractable to aptamer discovery. We are confident that these advanced aptamer-discovery methods will accelerate the discovery of aptamer reagents with excellent affinities and specificities, perhaps even exceeding those of the best monoclonal antibodies. Since aptamers are reproducible, renewable, stable, and can be distributed as sequence information, we anticipate that these affinity reagents will become even more valuable tools for both research and clinical applications. PMID:27526193

  8. Advanced Cell Development and Degradation Studies

    SciTech Connect

    J. E. O'Brien; C. M. Stoots; J. S. Herring; R. C. O'Brien; K. G. Condie; M. Sohal; G. K. Housley; J. J. Hartvigsen; D. Larsen; G. Tao; B. Yildiz; V. Sharma; P. Singh; N. Petigny; T. L. Cable

    2010-09-01

    The Idaho National Laboratory (INL) has been researching the application of solid-oxide electrolysis cells for large-scale hydrogen production from steam over a temperature range of 800 to 900ºC. From 2003 – 2009, this work was sponsored by the DOE Nuclear Hydrogen Initiative (NHI). Starting in 2010, the HTE research program has been sponsored by the Next Generation Nuclear Plant (NGNP) program. HTSE research priorities in FY10 are centered on understanding and reducing cell and stack performance degradation to an acceptable level to advance the technology readiness level of HTSE and to justify further large-scale demonstration activities. This report provides a summary of our FY10 experimental program, which has been focused on advanced cell and stack development and degradation studies. Advanced cell and stack development activities are under way at five technology partners: MSRI, Versa Power, Ceramatec, NASA Glenn, and St. Gobain. Performance evaluation of the advanced technology cells and stacks has been performed by the technology partners, by MIT and the University of Connecticut and at the INL HTE Laboratory. Summaries of these development activities and test results are presented.

  9. JPL Advanced Thermal Control Technology Roadmap - 2012

    NASA Technical Reports Server (NTRS)

    Birur, Gaj; Rodriguez, Jose I.

    2012-01-01

    NASA's new emphasis on human exploration program for missions beyond LEO requires development of innovative and revolutionary technologies. Thermal control requirements of future NASA science instruments and missions are very challenging and require advanced thermal control technologies. Limited resources requires organizations to cooperate and collaborate; government, industry, universities all need to work together for the successful development of these technologies.

  10. Identifying Advanced Technologies for Education's Future.

    ERIC Educational Resources Information Center

    Moore, Gwendolyn B.; Yin, Robert K.

    A study to determine how three advanced technologies might be applied to the needs of special education students helped inspire the development of a new method for identifying such applications. This new method, named the "Hybrid Approach," combines features of the two traditional methods: technology-push and demand-pull. Technology-push involves…

  11. Advanced technologies for Mission Control Centers

    NASA Technical Reports Server (NTRS)

    Dalton, John T.; Hughes, Peter M.

    1991-01-01

    Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

  12. Isotope separation and advanced manufacturing technology

    NASA Astrophysics Data System (ADS)

    Carpenter, J.; Kan, T.

    This is the fourth issue of a semiannual report for the Isotope Separation and Advanced Materials Manufacturing (ISAM) Technology Program at Lawrence Livermore National Laboratory. Primary objectives include: (1) the Uranium Atomic Vapor Laser Isotope Separation (UAVLIS) process, which is being developed and prepared for deployment as an advanced uranium enrichment capability; (2) Advanced manufacturing technologies, which include industrial laser and E-beam material processing and new manufacturing technologies for uranium, plutonium, and other strategically important materials in support of DOE and other national applications. This report features progress in the ISAM Program from October 1993 through March 1994.

  13. Low speed propellers: Impact of advanced technologies

    NASA Technical Reports Server (NTRS)

    Keiter, I. D.

    1980-01-01

    Sensitivity studies performed to evaluate the potential of several advanced technological elements on propeller performance, noise, weight, and cost for general aviation aircraft are discussed. Studies indicate that the application of advanced technologies to general aviation propellers can reduce fuel consumption in future aircraft an average of ten percent, meeting current regulatory noise limits. Through the use of composite blade construction, up to 25 percent propeller weight reduction can be achieved. This weight reduction in addition to seven percent propeller efficiency improvements through application of advanced technologies result in four percent reduction in direct operating costs, ten percent reduction in aircraft acquisition cost, and seven percent lower gross weight for general aviation aircraft.

  14. Hybrid Fuel Cell Technology Overview

    SciTech Connect

    None available

    2001-05-31

    For the purpose of this STI product and unless otherwise stated, hybrid fuel cell systems are power generation systems in which a high temperature fuel cell is combined with another power generating technology. The resulting system exhibits a synergism in which the combination performs with an efficiency far greater than can be provided by either system alone. Hybrid fuel cell designs under development include fuel cell with gas turbine, fuel cell with reciprocating (piston) engine, and designs that combine different fuel cell technologies. Hybrid systems have been extensively analyzed and studied over the past five years by the Department of Energy (DOE), industry, and others. These efforts have revealed that this combination is capable of providing remarkably high efficiencies. This attribute, combined with an inherent low level of pollutant emission, suggests that hybrid systems are likely to serve as the next generation of advanced power generation systems.

  15. Applications technology satellites advanced mission study

    NASA Technical Reports Server (NTRS)

    Gould, L. M.

    1972-01-01

    Three spacecraft configurations were designed for operation as a high powered synchronous communications satellite. Each spacecraft includes a 1 kw TWT and a 2 kw Klystron power amplifier feeding an antenna with multiple shaped beams. One of the spacecraft is designed to be boosted by a Thor-Delta launch vehicle and raised to synchronous orbit with electric propulsion. The other two are inserted into a elliptical transfer orbit with an Atlas Centaur and injected into final orbit with an apogee kick motor. Advanced technologies employed in the several configurations include tubes with multiple stage collectors radiating directly to space, multiple-contoured beam antennas, high voltage rollout solar cell arrays with integral power conditioning, electric propulsion for orbit raising and on-station attitude control and station-keeping, and liquid metal slip rings.

  16. Costs and Benefits of Advanced Aeronautical Technology

    NASA Technical Reports Server (NTRS)

    Bobick, J. C.; Denny, R. E.

    1983-01-01

    Programs available from COSMIC used to evaluate economic feasibility of applying advanced aeronautical technology to civil aircraft of future. Programs are composed of three major models: Fleet Accounting Module, Airframe manufacturer Module, and Air Carrier Module.

  17. Advancing Binaural Cochlear Implant Technology

    PubMed Central

    McAlpine, David

    2015-01-01

    This special issue contains a collection of 13 papers highlighting the collaborative research and engineering project entitled Advancing Binaural Cochlear Implant Technology—ABCIT—as well as research spin-offs from the project. In this introductory editorial, a brief history of the project is provided, alongside an overview of the studies. PMID:26721929

  18. Rotorcraft technology at Boeing Vertol: Recent advances

    NASA Technical Reports Server (NTRS)

    Shaw, John; Dadone, Leo; Wiesner, Robert

    1988-01-01

    An overview is presented of key accomplishments in the rotorcraft development at Boeing Vertol. Projects of particular significance: high speed rotor development and the Model 360 Advanced Technology Helicopter. Areas addressed in the overview are: advanced rotors with reduced noise and vibration, 3-D aerodynamic modeling, flight control and avionics, active control, automated diagnostics and prognostics, composite structures, and drive systems.

  19. Benefits of advanced propulsion technology for the advanced supersonic transport

    NASA Technical Reports Server (NTRS)

    Hines, R. W.; Sabatella, J. A.

    1973-01-01

    Future supersonic transports will have to provide improvement in the areas of economics, range, and emissions relative to the present generation of supersonic transports, as well as meeting or improving upon FAR 36 noise goals. This paper covers the promising propulsion systems including variable-cycle engine concepts for long-range supersonic commercial transport application. The benefits of applying advanced propulsion technology to solve the economic and environmental problems are reviewed. The advanced propulsion technologies covered are in the areas of structures, materials, cooling techniques, aerodynamics, variable engine geometry, jet noise suppressors, acoustic treatment, and low-emission burners. The results of applying the advanced propulsion technology are presented in terms of improvement in overall system takeoff gross weight and return on investment.

  20. Policy issues inherent in advanced technology development

    SciTech Connect

    Baumann, P.D.

    1994-12-31

    In the development of advanced technologies, there are several forces which are involved in the success of the development of those technologies. In the overall development of new technologies, a sufficient number of these forces must be present and working in order to have a successful opportunity at developing, introducing and integrating into the marketplace a new technology. This paper discusses some of these forces and how they enter into the equation for success in advanced technology research, development, demonstration, commercialization and deployment. This paper limits itself to programs which are generally governmental funded, which in essence represent most of the technology development efforts that provide defense, energy and environmental technological products. Along with the identification of these forces are some suggestions as to how changes may be brought about to better ensure success in a long term to attempt to minimize time and financial losses.

  1. Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    NASA Technical Reports Server (NTRS)

    Doyle, Monica; ONeil, Daniel A.; Christensen, Carissa B.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS) is a decision support tool designed to aid program managers and strategic planners in determining how to invest technology research and development dollars. It is an Excel-based modeling package that allows a user to build complex space architectures and evaluate the impact of various technology choices. ATLAS contains system models, cost and operations models, a campaign timeline and a centralized technology database. Technology data for all system models is drawn from a common database, the ATLAS Technology Tool Box (TTB). The TTB provides a comprehensive, architecture-independent technology database that is keyed to current and future timeframes.

  2. Advanced Refrigerator/Freezer Technology Development. Technology Assessment

    NASA Technical Reports Server (NTRS)

    Gaseor, Thomas; Hunter, Rick; Hamill, Doris

    1996-01-01

    The NASA Lewis Research Center, through contract with Oceaneering Space Systems, is engaged in a project to develop advanced refrigerator/freezer (R/F) technologies for future Life and Biomedical Sciences space flight missions. The first phase of this project, a technology assessment, has been completed to identify the advanced R/F technologies needed and best suited to meet the requirements for the five R/F classifications specified by Life and Biomedical Science researchers. Additional objectives of the technology assessment were to rank those technologies based on benefit and risk, and to recommend technology development activities that can be accomplished within this project. This report presents the basis, the methodology, and results of the R/F technology assessment, along with technology development recommendations.

  3. Advanced clean coal utilization technologies

    SciTech Connect

    Moritomi, Hiroshi

    1993-12-31

    The most important greenhouse gas is CO{sub 2} from coal utilization. Ways of mitigating CO{sub 2} emissions include the use of alternative fuels, using renewable resources and increasing the efficiency of power generation and end use. Adding to such greenhouse gas mitigation technologies, post combustion control by removing CO{sub 2} from power station flue gases and then storing or disposing it will be available. Although the post combustion control have to be evaluated in a systematic manner relating them to whether they are presently available technology, to be available in the near future or long term prospects requiring considerable development, it is considered to be a less promising option owing to the high cost and energy penalty. By contrast, abatement technologies aimed at improving conversion efficiency or reducing energy consumption will reduce emissions while having their own commercial justification.

  4. Assurance Technology Challenges of Advanced Space Systems

    NASA Technical Reports Server (NTRS)

    Chern, E. James

    2004-01-01

    The initiative to explore space and extend a human presence across our solar system to revisit the moon and Mars post enormous technological challenges to the nation's space agency and aerospace industry. Key areas of technology development needs to enable the endeavor include advanced materials, structures and mechanisms; micro/nano sensors and detectors; power generation, storage and management; advanced thermal and cryogenic control; guidance, navigation and control; command and data handling; advanced propulsion; advanced communication; on-board processing; advanced information technology systems; modular and reconfigurable systems; precision formation flying; solar sails; distributed observing systems; space robotics; and etc. Quality assurance concerns such as functional performance, structural integrity, radiation tolerance, health monitoring, diagnosis, maintenance, calibration, and initialization can affect the performance of systems and subsystems. It is thus imperative to employ innovative nondestructive evaluation methodologies to ensure quality and integrity of advanced space systems. Advancements in integrated multi-functional sensor systems, autonomous inspection approaches, distributed embedded sensors, roaming inspectors, and shape adaptive sensors are sought. Concepts in computational models for signal processing and data interpretation to establish quantitative characterization and event determination are also of interest. Prospective evaluation technologies include ultrasonics, laser ultrasonics, optics and fiber optics, shearography, video optics and metrology, thermography, electromagnetics, acoustic emission, x-ray, data management, biomimetics, and nano-scale sensing approaches for structural health monitoring.

  5. Technological Advances and the Study of Reading.

    ERIC Educational Resources Information Center

    Henk, William A.

    Recent technological advances in neuroanatomy and neurophysiology have unearthed structural and functional patterns in the brain that can be associated with severe reading disabilities. As a response, this paper examines several computer-driven technologies whose capabilities shed light on brain-related issues germane to reading, with the intent…

  6. One Micron Laser Technology Advancements at GSFC

    NASA Technical Reports Server (NTRS)

    Heaps, William S.

    2010-01-01

    This slide presentation reviews the advancements made in one micron laser technology at Goddard Space Flight Center. It includes information about risk factors that are being addressed by GSFC, and overviews of the various programs that GSFC is currently managing that are using 1 micron laser technology.

  7. Advancing Careers in Information Science and Technology

    ERIC Educational Resources Information Center

    Stanton, Wilbur W.; Templeton, Dennie E.; Chase, Joe D.; Rose, Melinda; Eaton, Carlotta

    2005-01-01

    The authors discuss the joining of 12 Virginia community colleges from the Appalachian region of southwestern Virginia with Radford University to form the Regional Technology Education Consortium (RTEC), a three-year project funded by the National Science Foundation Advanced Technological Education program and designed to develop articulation…

  8. Responding to Industry Demands: Advanced Technology Centers.

    ERIC Educational Resources Information Center

    Smith, Elizabeth Brient

    1991-01-01

    Discusses characteristics identified by the Center for Occupational Research and Development as indicative of fully functioning advanced technology centers, including the provision of training and retraining in such areas as design, manufacturing, materials science, and electro-optics; technology transfer; demonstration sites; needs assessment;…

  9. TECHcitement: Advances in Technological Education, 2007

    ERIC Educational Resources Information Center

    Patton, Madeline

    2007-01-01

    This publication presents the following nine articles: (1) ATE [Advanced Technological Education] Readies Technicians for International Competition; (2) Technicians in Demand Worldwide; (3) Accreditation Board for Engineering and Technology Endorses International Protocols for Technicians; (4) Entrepreneurial Educator Creates InnovaBio to Meet…

  10. Advanced technology development program for lithium-ion batteries : thermal abuse performance of 18650 Li-ion cells.

    SciTech Connect

    Crafts, Chris C.; Doughty, Daniel Harvey; McBreen, James.; Roth, Emanuel Peter

    2004-03-01

    Li-ion cells are being developed for high-power applications in hybrid electric vehicles currently being designed for the FreedomCAR (Freedom Cooperative Automotive Research) program. These cells offer superior performance in terms of power and energy density over current cell chemistries. Cells using this chemistry are the basis of battery systems for both gasoline and fuel cell based hybrids. However, the safety of these cells needs to be understood and improved for eventual widespread commercial application in hybrid electric vehicles. The thermal behavior of commercial and prototype cells has been measured under varying conditions of cell composition, age and state-of-charge (SOC). The thermal runaway behavior of full cells has been measured along with the thermal properties of the cell components. We have also measured gas generation and gas composition over the temperature range corresponding to the thermal runaway regime. These studies have allowed characterization of cell thermal abuse tolerance and an understanding of the mechanisms that result in cell thermal runaway.

  11. Advanced Lost Foam Casting Technology

    SciTech Connect

    Charles E. Bates; Harry E. Littleton; Don Askeland; Taras Molibog; Jason Hopper; Ben Vatankhah

    2000-11-30

    This report describes the research done under the six tasks to improve the process and make it more functional in an industrial environment. Task 1: Pattern Pyrolysis Products and Pattern Properties Task 2: Coating Quality Control Task 3: Fill and Solidification Code Task 4: Alternate Pattern Materials Task 5: Casting Distortion Task 6: Technology Transfer

  12. Advances in femtosecond laser technology

    PubMed Central

    Callou, Thais Pinheiro; Garcia, Renato; Mukai, Adriana; Giacomin, Natalia T; de Souza, Rodrigo Guimarães; Bechara, Samir J

    2016-01-01

    Femtosecond laser technology has become widely adopted by ophthalmic surgeons. The purpose of this study is to discuss applications and advantages of femtosecond lasers over traditional manual techniques, and related unique complications in cataract surgery and corneal refractive surgical procedures, including: LASIK flap creation, intracorneal ring segment implantation, presbyopic treatments, keratoplasty, astigmatic keratotomy, and intrastromal lenticule procedures. PMID:27143847

  13. Advances in femtosecond laser technology.

    PubMed

    Callou, Thais Pinheiro; Garcia, Renato; Mukai, Adriana; Giacomin, Natalia T; de Souza, Rodrigo Guimarães; Bechara, Samir J

    2016-01-01

    Femtosecond laser technology has become widely adopted by ophthalmic surgeons. The purpose of this study is to discuss applications and advantages of femtosecond lasers over traditional manual techniques, and related unique complications in cataract surgery and corneal refractive surgical procedures, including: LASIK flap creation, intracorneal ring segment implantation, presbyopic treatments, keratoplasty, astigmatic keratotomy, and intrastromal lenticule procedures.

  14. Recent advances in hypersonic technology

    NASA Technical Reports Server (NTRS)

    Dwoyer, Douglas L.

    1990-01-01

    This paper will focus on recent advances in hypersonic aerodynamic prediction techniques. Current capabilities of existing numerical methods for predicting high Mach number flows will be discussed and shortcomings will be identified. Physical models available for inclusion into modern codes for predicting the effects of transition and turbulence will also be outlined and their limitations identified. Chemical reaction models appropriate to high-speed flows will be addressed, and the impact of their inclusion in computational fluid dynamics codes will be discussed. Finally, the problem of validating predictive techniques for high Mach number flows will be addressed.

  15. Advanced Cogeneration Technology Economic Optimization Study (ACTEOS)

    NASA Technical Reports Server (NTRS)

    Nanda, P.; Ansu, Y.; Manuel, E. H., Jr.; Price, W. G., Jr.

    1980-01-01

    The advanced cogeneration technology economic optimization study (ACTEOS) was undertaken to extend the results of the cogeneration technology alternatives study (CTAS). Cost comparisons were made between designs involving advanced cogeneration technologies and designs involving either conventional cogeneration technologies or not involving cogeneration. For the specific equipment cost and fuel price assumptions made, it was found that: (1) coal based cogeneration systems offered appreciable cost savings over the no cogeneration case, while systems using coal derived liquids offered no costs savings; and (2) the advanced cogeneration systems provided somewhat larger cost savings than the conventional systems. Among the issues considered in the study included: (1) temporal variations in steam and electric demands; (2) requirements for reliability/standby capacity; (3) availability of discrete equipment sizes; (4) regional variations in fuel and electricity prices; (5) off design system performance; and (6) separate demand and energy charges for purchased electricity.

  16. Advanced Communication Technology Satellite (ACTS) multibeam antenna technology verification experiments

    NASA Technical Reports Server (NTRS)

    Acosta, Roberto J.; Larko, Jeffrey M.; Lagin, Alan R.

    1992-01-01

    The Advanced Communication Technology Satellite (ACTS) is a key to reaching NASA's goal of developing high-risk, advanced communications technology using multiple frequency bands to support the nation's future communication needs. Using the multiple, dynamic hopping spot beams, and advanced on board switching and processing systems, ACTS will open a new era in communications satellite technology. One of the key technologies to be validated as part of the ACTS program is the multibeam antenna with rapidly reconfigurable hopping and fixed spot beam to serve users equipped with small-aperature terminals within the coverage areas. The proposed antenna technology experiments are designed to evaluate in-orbit ACTS multibeam antenna performance (radiation pattern, gain, cross pol levels, etc.).

  17. Plasma Heating: An Advanced Technology

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The Mercury and Apollo spacecraft shields were designed to protect astronauts from high friction temperatures (well over 2,000 degrees Fahrenheit) when re-entering the Earth's atmosphere. It was necessary to test and verify the heat shield materials on Earth before space flight. After exhaustive research and testing, NASA decided to use plasma heating as a heat source. This technique involves passing a strong electric current through a rarefied gas to create a plasma (ionized gas) that produces an intensely hot flame. Although NASA did not invent the concept, its work expanded the market for commercial plasma heating systems. One company, Plasma Technology Corporation (PTC), was founded by a member of the team that developed the Re-entry Heating Simulator at Ames Research Center (ARC). Dr. Camacho, President of PTC, believes the technology has significant environmental applications. These include toxic waste disposal, hydrocarbon, decomposition, medical waste disposal, asbestos waste destruction, and chemical and radioactive waste disposal.

  18. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Schertler, Ronald J.; Gedney, Richard T.

    1992-01-01

    An overview of the NASA ACTS program is presented. The key technologies of ACTS include spot beams, on-board baseband processing and routing, wide bandwidth (900 MHz), and Ka-band transponders. The discussion covers system description, current status of the spacecraft development, ACTS earth stations, NGS traffic terminal, USAT, land and aeronautical mobiles, high data rate and propagation receive only terminals, and ACTS experiments program.

  19. Advances in core drilling technology

    NASA Astrophysics Data System (ADS)

    Holdsworth, G.

    Some notable technical advances in drill design were reported at the meeting, held in Canada August 30-September 1, 1982, at the University of Calgary. Chief amongst these was a battery powered, computer assisted electromechanical core drill which has recently been used by the Danes in Greenland to continuously core to the base of the ice sheet at 2038 m. This is the deepest coring operation so far on the Greenland ice sheet. (The record for deep glacier drilling is held by the U.S. Army Cold Regions Research and Engineering Laboratory for the continuous coring through 2164 m of ice to bedrock at Byrd Station, Antarctica, in 1968). In early 1982, a current Soviet core drilling operation was reported to be at a depth of 2000 m at Vostok station, Antarctica, where the total ice thickness is about 4000 m; the goal of core drilling the entire ice thickness there could be achieved before the end of 1983.

  20. Advances in pipe prover technology

    SciTech Connect

    Jakubenas, P.P.

    1996-09-01

    The petroleum industry has used pipe provers for on line calibration of liquid flow meters for over 30 years. Recently a number of innovations have come to the forefront that enhance the reliability of pipe provers, reduce their size, make them more accurate, and increase their value to the end users. With the widespread use of turbine meters for custody transfer, accurate measurement is more dependent on frequent proving, thus the industry will continue to demand advanced provers and proving techniques. The author will discuss the aforementioned subject with regard to both bidirectional and unidirectional pipe provers. A description of the operational principles of pipe provers and the enhancements that are now available in terms of prover mechanical configuration and electronic instrumentation will be described in detail. In addition, information will be provided concerning integration of pipe provers into measurement systems and design and use of sophisticated computer control systems for automated proving.

  1. Ceramic Technology for Advanced Heat Engines Project

    SciTech Connect

    Not Available

    1990-08-01

    The Ceramic Technology For Advanced Heat Engines Project was developed by the Department of Energy's Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS's Advanced Materials Development Program, was developed to meet the ceramic technology requirements of the OTS's automotive technology programs. Significant accomplishments in fabricating ceramic components for the Department of Energy (DOE), National Aeronautics and Space Administration (NASA), and Department of Defense (DOD) advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. However, these programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and data base and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. An assessment of needs was completed, and a five year project plan was developed with extensive input from private industry. The objective of the project is to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on structural ceramics for advanced gas turbine and diesel engines, ceramic hearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines.

  2. Space platform advanced technology study

    NASA Technical Reports Server (NTRS)

    Burns, G.

    1981-01-01

    Current and past space platform and power module studies were utilized to point the way to areas of development for mechanical devices that will be required for the ultimate implementation of a platform erected and serviced by the Shuttle/Orbiter. The study was performed in accordance with a study plan which included: a review of space platform technology; orbiter berthing system requirements; berthing latch interface requirements, design, and model fabrication; berthing umbilical interface requirements and design; adaptive end effector design and model fabrication; and adaptive end effector requirements.

  3. Advanced neutral-beam technology

    SciTech Connect

    Berkner, K.H.

    1980-09-01

    Extensive development will be required to achieve the 50- to 75-MW, 175- to 200-keV, 5- to 10-sec pulses of deuterium atoms envisioned for ETF and INTOR. Multi-megawatt injector systems are large (and expansive); they consist of large vacuum tanks with many square meters of cryogenic pumping panels, beam dumps capable of dissipating several megawatts of un-neutralized beam, bending magnets, electrical power systems capable of fast turnoff with low (capacity) stored energy, and, of course, the injector modules (ion sources and accelerators). The technology requirements associated with these components are described.

  4. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-11-04

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  5. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2006-05-15

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  6. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher E. Hull

    2006-09-30

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  7. Advanced RF Front End Technology

    NASA Technical Reports Server (NTRS)

    Herman, M. I.; Valas, S.; Katehi, L. P. B.

    2001-01-01

    The ability to achieve low-mass low-cost micro/nanospacecraft for Deep Space exploration requires extensive miniaturization of all subsystems. The front end of the Telecommunication subsystem is an area in which major mass (factor of 10) and volume (factor of 100) reduction can be achieved via the development of new silicon based micromachined technology and devices. Major components that make up the front end include single-pole and double-throw switches, diplexer, and solid state power amplifier. JPL's Center For Space Microsystems - System On A Chip (SOAC) Program has addressed the challenges of front end miniaturization (switches and diplexers). Our objectives were to develop the main components that comprise a communication front end and enable integration in a single module that we refer to as a 'cube'. In this paper we will provide the latest status of our Microelectromechanical System (MEMS) switches and surface micromachined filter development. Based on the significant progress achieved we can begin to provide guidelines of the proper system insertion for these emerging technologies. Additional information is contained in the original extended abstract.

  8. Advanced nuclear energy analysis technology.

    SciTech Connect

    Gauntt, Randall O.; Murata, Kenneth K.; Romero, Vicente JosÔe; Young, Michael Francis; Rochau, Gary Eugene

    2004-05-01

    A two-year effort focused on applying ASCI technology developed for the analysis of weapons systems to the state-of-the-art accident analysis of a nuclear reactor system was proposed. The Sandia SIERRA parallel computing platform for ASCI codes includes high-fidelity thermal, fluids, and structural codes whose coupling through SIERRA can be specifically tailored to the particular problem at hand to analyze complex multiphysics problems. Presently, however, the suite lacks several physics modules unique to the analysis of nuclear reactors. The NRC MELCOR code, not presently part of SIERRA, was developed to analyze severe accidents in present-technology reactor systems. We attempted to: (1) evaluate the SIERRA code suite for its current applicability to the analysis of next generation nuclear reactors, and the feasibility of implementing MELCOR models into the SIERRA suite, (2) examine the possibility of augmenting ASCI codes or alternatives by coupling to the MELCOR code, or portions thereof, to address physics particular to nuclear reactor issues, especially those facing next generation reactor designs, and (3) apply the coupled code set to a demonstration problem involving a nuclear reactor system. We were successful in completing the first two in sufficient detail to determine that an extensive demonstration problem was not feasible at this time. In the future, completion of this research would demonstrate the feasibility of performing high fidelity and rapid analyses of safety and design issues needed to support the development of next generation power reactor systems.

  9. Advanced Microwave/Millimeter-Wave Imaging Technology

    NASA Astrophysics Data System (ADS)

    Shen, Zuowei; Yang, Lu; Luhmann, N. C., Jr.; Domier, C. W.; Ito, N.; Kogi, Y.; Liang, Y.; Mase, A.; Park, H.; Sakata, E.; Tsai, W.; Xia, Z. G.; Zhang, P.

    Millimeter wave technology advances have made possible active and passive millimeter wave imaging for a variety of applications including advanced plasma diagnostics, radio astronomy, atmospheric radiometry, concealed weapon detection, all-weather aircraft landing, contraband goods detection, harbor navigation/surveillance in fog, highway traffic monitoring in fog, helicopter and automotive collision avoidance in fog, and environmental remote sensing data associated with weather, pollution, soil moisture, oil spill detection, and monitoring of forest fires, to name but a few. The primary focus of this paper is on technology advances which have made possible advanced imaging and visualization of magnetohydrodynamic (MHD) fluctuations and microturbulence in fusion plasmas. Topics of particular emphasis include frequency selective surfaces, planar Schottky diode mixer arrays, electronically controlled beam shaping/steering arrays, and high power millimeter wave local oscillator and probe sources.

  10. Advanced technologies for remote sensing imaging applications

    SciTech Connect

    Wood, L.L.

    1993-06-07

    Generating and returning imagery from great distances has been generally associated with national security activities, with emphasis on reliability of system operation. (While the introduction of such capabilities was usually characterized by high levels of innovation, the evolution of such systems has followed the classical track of proliferation of ``standardized items`` expressing ever more incremental technological advances.) Recent focusing of interest on the use of remote imaging systems for commercial and scientific purposes can be expected to induce comparatively rapid advances along the axes of efficiency and technological sophistication, respectively. This paper reviews the most basic reasons for expecting the next decade of advances to dwarf the impressive accomplishments of the past ten years. The impact of these advances clearly will be felt in all major areas of large-scale human endeavor, commercial, military and scientific.

  11. DOE/JPL advanced thermionic technology program

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Progress made in different tasks of the advanced thermionic technology program is described. The tasks include surface and plasma investigations (surface characterization, spectroscopic plasma experiments, and converter theory); low temperature converter development (tungsten emitter, tungsten oxide collector and tungsten emitter, nickel collector); component hardware development (hot shell development); flame-fired silicon carbide converters; high temperature and advanced converter studies; postoperational diagnostics; and correlation of design interfaces.

  12. Electrochromic Windows: Advanced Processing Technology

    SciTech Connect

    SAGE Electrochromics, Inc

    2006-12-13

    This project addresses the development of advanced fabrication capabilities for energy saving electrochromic (EC) windows. SAGE EC windows consist of an inorganic stack of thin films deposited onto a glass substrate. The window tint can be reversibly changed by the application of a low power dc voltage. This property can be used to modulate the amount of light and heat entering buildings (or vehicles) through the glazings. By judicious management of this so-called solar heat gain, it is possible to derive significant energy savings due to reductions in heating lighting, and air conditioning (HVAC). Several areas of SAGE’s production were targeted during this project to allow significant improvements to processing throughput, yield and overall quality of the processing, in an effort to reduce the cost and thereby improve the market penetration. First, the overall thin film process was optimized to allow a more robust set of operating points to be used, thereby maximizing the yield due to the thin film deposition themselves. Other significant efforts aimed at improving yield were relating to implementing new procedures and processes for the manufacturing process, to improve the quality of the substrate preparation, and the quality of the IGU fabrication. Furthermore, methods for reworking defective devices were developed, to enable devices which would otherwise be scrapped to be made into useful product. This involved the in-house development of some customized equipment. Finally, the improvements made during this project were validated to ensure that they did not impact the exceptional durability of the SageGlass® products. Given conservative estimates for cost and market penetration, energy savings due to EC windows in residences in the US are calculated to be of the order 0.026 quad (0.026×1015BTU/yr) by the year 2017.

  13. Technological Advances in Psychiatric Nursing: An update.

    PubMed

    Bostrom, Andrea C

    2016-06-01

    Understanding and treating mental illness has improved in many ways as a result of the fast pace of technological advances. The technologies that have the greatest potential impact are those that (1) increase the knowledge of how the brain functions and changes based on interventions, (2) have the potential to personalize interventions based on understanding genetic factors of drug metabolism and pharmacodynamics, and (3) use information technology to provide treatment in the absence of an adequate mental health workforce. Technologies are explored for psychiatric nurses to consider. Psychiatric nurses are encouraged to consider the experiences of psychiatric patients, including poor health, stigmatization, and suffering.

  14. Technological advances for studying human behavior

    NASA Technical Reports Server (NTRS)

    Roske-Hofstrand, Renate J.

    1990-01-01

    Technological advances for studying human behavior are noted in viewgraph form. It is asserted that performance-aiding systems are proliferating without a fundamental understanding of how they would interact with the humans who must control them. Two views of automation research, the hardware view and the human-centered view, are listed. Other viewgraphs give information on vital elements for human-centered research, a continuum of the research process, available technologies, new technologies for persistent problems, a sample research infrastructure, the need for metrics, and examples of data-link technology.

  15. Advanced photovoltaic power system technology for lunar base applications

    NASA Technical Reports Server (NTRS)

    Brinker, David J.; Flood, Dennis J.

    1992-01-01

    The development of an advanced photovoltaic power system that would have application for a manned lunar base is currently planned under the Surface Power element of Pathfinder. Significant mass savings over state-of-the-art photovoltaic/battery systems are possible with the use of advanced lightweight solar arrays coupled with regenerative fuel cell storage. The solar blanket, using either ultrathin GaAs or amorphous silicon solar cells, would be integrated with a reduced-g structure. Regenerative fuel cells with high-pressure gas storage in filament-wound tanks are planned for energy storage. An advanced PV/RFC power system is a leading candidate for a manned lunar base as it offers a tremendous weight advantage over state-of-the-art photovoltaic/battery systems and is comparable in mass to other advanced power generation technologies.

  16. The Advanced Technology Operations System: ATOS

    NASA Technical Reports Server (NTRS)

    Kaufeler, J.-F.; Laue, H. A.; Poulter, K.; Smith, H.

    1993-01-01

    Mission control systems supporting new space missions face ever-increasing requirements in terms of functionality, performance, reliability and efficiency. Modern data processing technology is providing the means to meet these requirements in new systems under development. During the past few years the European Space Operations Centre (ESOC) of the European Space Agency (ESA) has carried out a number of projects to demonstrate the feasibility of using advanced software technology, in particular, knowledge based systems, to support mission operations. A number of advances must be achieved before these techniques can be moved towards operational use in future missions, namely, integration of the applications into a single system framework and generalization of the applications so that they are mission independent. In order to achieve this goal, ESA initiated the Advanced Technology Operations System (ATOS) program, which will develop the infrastructure to support advanced software technology in mission operations, and provide applications modules to initially support: Mission Preparation, Mission Planning, Computer Assisted Operations, and Advanced Training. The first phase of the ATOS program is tasked with the goal of designing and prototyping the necessary system infrastructure to support the rest of the program. The major components of the ATOS architecture is presented. This architecture relies on the concept of a Mission Information Base (MIB) as the repository for all information and knowledge which will be used by the advanced application modules in future mission control systems. The MIB is being designed to exploit the latest in database and knowledge representation technology in an open and distributed system. In conclusion the technological and implementation challenges expected to be encountered, as well as the future plans and time scale of the project, are presented.

  17. Advances in ambient temperature secondary lithium cells

    NASA Technical Reports Server (NTRS)

    Subbarao, S.; Shen, D. H.; Deligiannis, F.; Huang, C-K.; Halpert, G.

    1989-01-01

    The goal is to develop secondary lithium cells with a 100 Wh/kg specific energy capable of 1000 cycles at 50 percent DOD. The approach towards meeting this goal initially focused on several basic issues related to the cell chemistry, selection of cathode materials and electrolytes and component development. The performance potential of Li-TiS2, Li-MoS3, Li-V6O13 and Li-NbSe3 electrochemical systems was examined. Among these four, the Li-TiS2 system was found to be the most promising system in terms of achievable specific energy and cycle life. Major advancements to date in the development of Li-TiS2 cells are in the areas of cathode processing technology, mixed solvent electrolytes, and cell assembly. A summary is given of these advances.

  18. Advanced MCT technologies in France

    NASA Astrophysics Data System (ADS)

    Destefanis, Gérard; Tribolet, Philippe

    2007-04-01

    In this paper we present an overview of the very recent developments of the HgCdTe infrared detector technology developed by CEA-LETI and industrialized by Sofradir in France. Today Sofradir uses in production for more than 15years a very mature, reproducible, well mastered and fully understood, planar n on p ion implanted technology. This process that allows very high yields to be achieved in all infrared bands from SWIR to LWIR uses the very conventional approach of LPE growth of MCT on lattice-matched CdZnTe substrates. Progress in this field is continuous from 20years and has recently leaded to the fabrication of high performance VLWIR FPA (320x256 with cut off wavelengths as high as 20μm). Moreover, thanks to the design of the epitaxial structure and to the substrate removal step MCT FPAs present the unique features to have very high quantum efficiency (above 70%) from the cut off wavelength down to the UV. This effect, which opens new application fields, was recently demonstrated in SWIR 320x256 FPAs with cut off wavelength of 2.5μm. Very high quality FPAs (1280x1024) with pitches as small as 15μm have already been demonstrated last year using the MBE growth of MWIR MCT epilayers on 4 inches germanium substrates, n on p ion implanted photodiodes and the hot welding indium bump hybridization technique. At the same time, with the MBE growth, bicolor and dual band FPAs which uses more complex multi hetero-junctions architectures (both 4 layers npn and 'pseudo planar' structures and extrinsically doped MCT layers) were fabricated with formats of 320x256 and pitches as small as 25μm. A very new area of development concerns avalanche photodiodes (APD) made with MCT. This semiconductor presents a unique feature among all the over semiconductors. Extremely high avalanche gains can be obtained on n on p photodiodes without absolutely any noise excess (F(K)=1): MCT APDs act as perfect amplifiers. These results open new interesting fields of investigation for low

  19. Reliability modelling system for analysis of advanced battery technologies

    NASA Astrophysics Data System (ADS)

    Imhoff, C. H.; Hostick, C. J.; Nakaoka, R. K.

    1985-05-01

    Key considerations in evaluating the reliability of advanced battery technologies include the impact of cell failures on battery performance and cost. Pacific Northwest Laboratory developed interactive microcomputer based simulation models to help battery developers use cell reliability data to calculate the expected performance of new battery technologies. Key benefits of this model include its capability to estimate the effect of cell failures upon: (1) battery system discharge performance, (2) system cycle life, and (3) system economic performance (tradeoffs between capital investment and lifetime operating costs).

  20. Advancing Autonomous Operations Technologies for NASA Missions

    NASA Technical Reports Server (NTRS)

    Cruzen, Craig; Thompson, Jerry Todd

    2013-01-01

    This paper discusses the importance of implementing advanced autonomous technologies supporting operations of future NASA missions. The ability for crewed, uncrewed and even ground support systems to be capable of mission support without external interaction or control has become essential as space exploration moves further out into the solar system. The push to develop and utilize autonomous technologies for NASA mission operations stems in part from the need to reduce operations cost while improving and increasing capability and safety. This paper will provide examples of autonomous technologies currently in use at NASA and will identify opportunities to advance existing autonomous technologies that will enhance mission success by reducing operations cost, ameliorating inefficiencies, and mitigating catastrophic anomalies.

  1. Advanced sensing technology in environmental field.

    PubMed

    Wakida, Shin-ichi

    2009-01-01

    Before the introduction of advanced sensing technology in environmental fields, environmental issues were discussed as several categories, such as local environmental issues in the 1970s, global environmental issues in the 1980s, living environmental issues in the 2000s and environmental stress issues in near future, which are of increasing interest in Japan. Using advanced sensing technologies, such as electrochemical sensors, chemically-sensitive field-effect transistors (ChemFETs) based on micro-electro mechanical system (MEMS) micromachining technology and subsequently electrophoretic separation and microfluidic Lab-on-a-Chip using MEMS technology, we have steered several kinds of environmental monitoring projects timely in response to the environmental issues for over the last 25 years. Among the local environmental issues, the global environmental issues and the living environmental issues, some fruits of R&D project will be introduced. Finally, our latest concern of the environmental stress monitoring was discussed and preliminary results were also introduced.

  2. Materials International Space Station Experiment (MISSE) 5 Developed to Test Advanced Solar Cell Technology Aboard the ISS

    NASA Technical Reports Server (NTRS)

    Wilt, David M.

    2004-01-01

    The testing of new technologies aboard the International Space Station (ISS) is facilitated through the use of a passive experiment container, or PEC, developed at the NASA Langley Research Center. The PEC is an aluminum suitcase approximately 2 ft square and 5 in. thick. Inside the PEC are mounted Materials International Space Station Experiment (MISSE) plates that contain the test articles. The PEC is carried to the ISS aboard the space shuttle or a Russian resupply vehicle, where astronauts attach it to a handrail on the outer surface of the ISS and deploy the PEC, which is to say the suitcase is opened 180 deg. Typically, the PEC is left in this position for approximately 1 year, at which point astronauts close the PEC and it is returned to Earth. In the past, the PECs have contained passive experiments, principally designed to characterize the durability of materials subjected to the ultraviolet radiation and atomic oxygen present at the ISS orbit. The MISSE5 experiment is intended to characterize state-of-art (SOA) and beyond photovoltaic technologies.

  3. Advanced Technology Development for Stirling Convertors

    NASA Technical Reports Server (NTRS)

    Thieme, Lanny G.; Schreiber, Jeffrey G.

    2004-01-01

    A high-efficiency Stirling Radioisotope generator (SRG) for use on potential NASA space missions is being developed by the Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center. GRC is also developing advanced technology for Stirling converters, aimed at substantially improving the specific power and efficiency of the converter.The status and results to date will be discussed in this paper.

  4. Advanced photovoltaic power system technology for lunar base applications

    NASA Technical Reports Server (NTRS)

    Brinker, David J.; Flood, Dennis J.

    1988-01-01

    Advanced photovoltaic/electrochemical (batteries or regenerative fuel cells for storage) power system options for a lunar base are discussed and compared. Estimated system masses are compared with those projected for the SP-100 nuclear system. The results of the comparison are quantified in terms of the mass saved in a scenario which assembles the initial base elements in Low Earth Orbit (LEO) and launches from there to the lunar surface. A brief summary is given of advances in photovoltaic/electrochemical power system technologies currently under development in the NASA/OAST program. A description of the planned focussed technology program for surface power in the new Pathfinder initiative is also provided.

  5. FY 2007 Progress Report for Advanced Combustion Engine Technologies

    SciTech Connect

    None, None

    2007-12-01

    Advanced combustion engines have great potential for achieving dramatic energy efficiency improvements in light-duty vehicle applications, where it is suited to both conventional and hybrid- electric powertrain configurations. Light-duty vehicles with advanced combustion engines can compete directly with gasoline engine hybrid vehicles in terms of fuel economy and consumer-friendly driving characteristics; also, they are projected to have energy efficiencies that are competitive with hydrogen fuel cell vehicles when used in hybrid applications.Advanced engine technologies being researched and developed by the Advanced Combustion Engine R&D Sub-Program will also allow the use of hydrogen as a fuel in ICEs and will provide an energy-efficient interim hydrogen-based powertrain technology during the transition to hydrogen/fuelcell-powered transportation vehicles.

  6. Advances in technologies and study design

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Completion of the initial draft sequence of the human genome was the proving ground for and has ushered in significant advancements in technology of increasing sophistication and ever increasing amounts of data. Often, this combination has a multiplicative effect of stimulating research groups to co...

  7. Advanced Technological Education Survey 2011 Fact Sheet

    ERIC Educational Resources Information Center

    Wingate, Lori; Westine, Carl; Gullickson, Arlen

    2011-01-01

    This fact sheet summarizes data gathered in the 2011 survey of National Science Foundation (NSF) Advanced Technological Education (ATE) grant recipients. Conducted by EvaluATE, the evaluation resource center for the ATE program located at The Evaluation Center at Western Michigan University, this was the twelfth annual survey of ATE projects and…

  8. Advanced Technological Education Survey 2012 Fact Sheet

    ERIC Educational Resources Information Center

    Wingate, Lori; Smith, Corey; Westine, Carl; Gullickson, Arlen

    2012-01-01

    This fact sheet summarizes data gathered in the 2012 survey of National Science Foundation (NSF) Advanced Technological Education (ATE) grant recipients. Conducted by EvaluATE, the evaluation resource center for the ATE program located at The Evaluation Center at Western Michigan University, this was the thirteenth annual survey of ATE projects…

  9. TECHcitement: Advances in Technological Education, 2006

    ERIC Educational Resources Information Center

    American Association of Community Colleges (NJ1), 2006

    2006-01-01

    This publication includes 13 articles: (1) ATE [Advanced Technological Education] Attuned to Global Competition; (2) Materials Science Center Supplies Information on Often-Overlooked Field; (3) CSEC [Cyber Security Education Consortium] Builds Corps of Cyber Technicians; (4) KCTCS [Kentucky Community and Technical College System] Is U.S. Partner…

  10. Advanced Technological Education Survey 2010 Fact Sheet

    ERIC Educational Resources Information Center

    Wingate, Lori; Westine, Carl; Gullickson, Arlen

    2010-01-01

    This fact sheet summarizes data gathered in the 2010 survey of National Science Foundation (NSF) Advanced Technological Education (ATE) grant recipients. Conducted by EvaluATE, the evaluation resource center for the ATE program located at The Evaluation Center at Western Michigan University, this was the eleventh annual survey of ATE projects and…

  11. Advanced Technological Education Survey 2009 Fact Sheet

    ERIC Educational Resources Information Center

    Wingate, Lori; Gullickson, Arlen

    2009-01-01

    This fact sheet summarizes data gathered in the 2009 survey of National Science Foundation (NSF) Advanced Technological Education (ATE) grant recipients. Conducted by The Evaluation Center at Western Michigan University, this was the tenth annual survey of ATE projects and centers. Included here are statistics about the program's grantees and…

  12. Why Video? How Technology Advances Method

    ERIC Educational Resources Information Center

    Downing, Martin J., Jr.

    2008-01-01

    This paper reports on the use of video to enhance qualitative research. Advances in technology have improved our ability to capture lived experiences through visual means. I reflect on my previous work with individuals living with HIV/AIDS, the results of which are described in another paper, to evaluate the effectiveness of video as a medium that…

  13. TECHcitement: Advances in Technology Education, 2008

    ERIC Educational Resources Information Center

    Patton, Madeline

    2008-01-01

    This publication presents the following articles: (1) Advanced Technological Education (ATE) Develops Student Recruitment and Retention Strategies; (2) Marketer Advises Tech Educators Appeal to Teens' Emotions, Desires to Do Something Important; (3) Digital Bridge Academy Gets At-Risk Students on Paths to Knowledge-Based Careers; (4) Project…

  14. TECHcitement: Advances in Technological Education, 2004

    ERIC Educational Resources Information Center

    American Association of Community Colleges (NJ1), 2004

    2004-01-01

    This edition of "TECHcitement" contains the following articles: (1) ATE Program Leads to Student Success; (2) Doing Whatever It Takes for Aquaculture; (3) The Bridge to Biotech; (4) Girls See What They Can Do With Technology at Camp; (5) Students Advancing Solutions to Business Problems; (6) CREATE Recreates Technical Education in California; (7)…

  15. Advances in technologies and study design.

    PubMed

    Parnell, Laurence D

    2012-01-01

    The initial draft sequence of the human genome was the proving ground for significant technological advancements, and its completion has ushered in increasingly sophisticated tools and ever-increasing amounts of data. Often, this combination has multiplicative effects such as stimulating research groups to consider subsequent experiments of at least equal if not greater complexity or employ advanced technologies. As applied to the fields of nutrigenetics and nutrigenomics, these advances in technology and experimental design allow researchers to probe the biological, biochemical, and physiological mechanisms underpinning the response to micro- and macronutrients, along with downstream health effects. It is becoming ever more apparent that effects on gene expression as a consequence of genetic variation and perturbations to cellular and physiological systems are an important cornerstone of nutrigenomics and nutrigenetics research. A critical, near-term objective, however, must be to determine where and how nutrients and their metabolites augment or disrupt the genetic variation-gene expression axis. Downstream effects on protein and metabolite measures are also seen with growing regularity as vital components to this research. Thus, this chapter reviews the scope of recent progress and innovation in genomics and associated technologies as well as study designs as applied to nutrigenomics and nutrigenetics research and provides concrete examples of the application of those advancements in genomics-oriented nutrition research.

  16. Advanced Stirling Convertor (ASC) Technology Maturation

    NASA Technical Reports Server (NTRS)

    Wong, Wayne A.; Wilson, Scott; Collins, Josh; Wilson, Kyle

    2016-01-01

    The Advanced Stirling Convertor (ASC) development effort was initiated by NASA Glenn Research Center with contractor Sunpower, Inc., to develop high-efficiency thermal-to-electric power conversion technology for NASA Radioisotope Power Systems (RPSs). Early successful performance demonstrations led to the expansion of the project as well as adoption of the technology by the Department of Energy (DOE) and system integration contractor Lockheed Martin Space Systems Company as part of the Advanced Stirling Radioisotope Generator (ASRG) flight project. The ASRG integrates a pair of ASCs to convert the heat from a pair of General Purpose Heat Source (GPHS) modules into electrical power. The expanded NASA ASC effort included development of several generations of ASC prototypes or engineering units to help prepare the ASC technology and Sunpower for flight implementation. Sunpower later had two parallel contracts allowing the last of the NASA engineering units called ASC-E3 to serve as pathfinders for the ASC-F flight convertors being built for DOE. The ASC-E3 convertors utilized the ASC-F flight specifications and were built using the ASC-F design and process documentation. Shortly after the first ASC-F pair achieved initial operation, due to budget constraints, the DOE ASRG flight development contract was terminated. NASA continues to invest in the development of Stirling RPS technology including continued production of the ASC-E3 convertors, seven of which have been delivered with one additional unit in production. Starting in fiscal year 2015, Stirling Convertor Technology Maturation has been reorganized as an element of the RPS Stirling Cycle Technology Development (SCTD) Project and long-term plans for continued Stirling technology advancement are in reformulation. This paper provides a status on the ASC project, an overview of advancements made in the design and production of the ASC at Sunpower, and a summary of acceptance tests, reliability tests, and tactical

  17. Advanced Stirling Convertor (ASC) Technology Maturation

    NASA Technical Reports Server (NTRS)

    Wong, Wayne A.; Wilson, Scott; Collins, Josh; Wilson, Kyle

    2015-01-01

    The Advanced Stirling Convertor (ASC) development effort was initiated by NASA Glenn Research Center (GRC) with contractor Sunpower Inc. to develop high efficiency thermal-to-electric power conversion technology for NASA Radioisotope Power Systems. Early successful performance demonstrations led to the expansion of the project as well as adoption of the technology by the Department of Energy (DOE) and system integration contractor Lockheed Martin Space Systems Company as part of the Advanced Stirling Radioisotope Generator (ASRG) flight project. The ASRG integrates a pair of ASCs to convert the heat from a pair of General Purpose Heat Source (GPHS) modules into electrical power. The expanded NASA ASC effort included development of several generations of ASC prototypes or Engineering Units to help prepare the ASC technology and Sunpower for flight implementation. Sunpower later had two parallel contracts allowing the last of the NASA Engineering Units called ASC-E3 to serve as pathfinders for the ASC-F flight convertors being built for DOE. The ASC-E3 convertors utilized the ASC-F flight specifications and were built using the ASC-F design and process documentation. Shortly after the first ASC-F Pair achieved initial operation, due to budget constraints, the DOE ASRG flight development contract was terminated. NASA continues to invest in the development of Stirling RPS technology including continued production of the ASC-E3 convertors, seven of which have been delivered with one additional unit in production. Starting in FY2015, Stirling Convertor Technology Maturation has been reorganized as an element of the RPS Stirling Cycle Technology Development (SCTD) Project and long-term plans for continued Stirling technology advancement are in reformulation. This paper provides a status on the ASC project, an overview of advancements made in the design and production of the ASC at Sunpower, and a summary of acceptance tests, reliability tests, and tactical tests at NASA

  18. NASA/industry advanced turboprop technology program

    NASA Technical Reports Server (NTRS)

    Ziemianski, Joseph A.; Whitlow, John B., Jr.

    1988-01-01

    Experimental and analytical effort shows that use of advanced turboprop (propfan) propulsion instead of conventional turbofans in the older narrow-body airline fleet could reduce fuel consumption for this type of aircraft by up to 50 percent. The NASA Advanced Turboprop (ATP) program was formulated to address the key technologies required for these thin, swept-blade propeller concepts. A NASA, industry, and university team was assembled to develop and validate applicable design codes and prove by ground and flight test the viability of these propeller concepts. Some of the history of the ATP Project, an overview of some of the issues, and a summary of the technology developed to make advanced propellers viable in the high-subsonic cruise speed application are presented. The ATP program was awarded the prestigious Robert J. Collier Trophy for the greatest achievement in aeronautics and astronautics in America in 1987.

  19. NASA/industry advanced turboprop technology program

    NASA Technical Reports Server (NTRS)

    Ziemianski, Joseph A.; Whitlow, John B., Jr.

    1988-01-01

    Experimental and analytical effort shows that use of advanced turboprop (propfan) propulsion instead of conventional turbofans in the older narrow-body airline fleet could reduce fuel consumption for this type of aircraft by up to 50 percent. The NASA Advanced Turboprop (ATP) program was formulated to address the key technologies required for these thin, swept-blade propeller concepts. A NASA, industry, and university team was assembled to develop and validate applicable design codes and prove by ground and flight test the viability of these propeller concepts. Some of the history of the ATP project, an overview of some of the issues, and a summary of the technology developed to make advanced propellers viable in the high-subsonic cruise speed application are presented. The ATP program was awarded the prestigious Robert J. Collier Trophy for the greatest achievement in aeronautics and astronautics in America in 1987.

  20. Advanced Engineering Technology for Measuring Performance.

    PubMed

    Rutherford, Drew N; D'Angelo, Anne-Lise D; Law, Katherine E; Pugh, Carla M

    2015-08-01

    The demand for competency-based assessments in surgical training is growing. Use of advanced engineering technology for clinical skills assessment allows for objective measures of hands-on performance. Clinical performance can be assessed in several ways via quantification of an assessee's hand movements (motion tracking), direction of visual attention (eye tracking), levels of stress (physiologic marker measurements), and location and pressure of palpation (force measurements). Innovations in video recording technology and qualitative analysis tools allow for a combination of observer- and technology-based assessments. Overall the goal is to create better assessments of surgical performance with robust validity evidence.

  1. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Work to develop and demonstrate the technology of structural ceramics for automotive engines and similar applications is described. Long-range technology is being sought to produce gas turbine engines for automobiles with reduced fuel consumption and reduced environmental impact. The Advanced Turbine Technology Application Project (ATTAP) test bed engine is designed such that, when installed in a 3,000 pound inertia weight automobile, it will provide low emissions, 42 miles per gallon fuel economy on diesel fuel, multifuel capability, costs competitive with current spark ignition engines, and noise and safety characteristics that meet Federal standards.

  2. Technology advancement of an oxygen generation subsystem

    NASA Technical Reports Server (NTRS)

    Lee, M. K.; Burke, K. A.; Schubert, F. H.; Wynveen, R. A.

    1979-01-01

    An oxygen generation subsystem based on water electrolysis was developed and tested to further advance the concept and technology of the spacecraft air revitalization system. Emphasis was placed on demonstrating the subsystem integration concept and hardware maturity at a subsystem level. The integration concept of the air revitalization system was found to be feasible. Hardware and technology of the oxygen generation subsystem was demonstrated to be close to the preprototype level. Continued development of the oxygen generation technology is recommended to further reduce the total weight penalties of the oxygen generation subsystem through optimization.

  3. Advanced technologies for perimeter intrusion detection sensors

    SciTech Connect

    Williams, J.D.

    1995-03-01

    The development of integrated circuit fabrication techniques and the resulting devices have contributed more to the advancement of exterior intrusion detectors and alarm assessment devices than any other technology. The availability of this technology has led to the improvements in and further development of smaller more powerful computers, microprocessors, solid state memories, solid state cameras, thermal imagers, low-power lasers, and shorter pulse width and higher frequency electronic circuitry. This paper presents information on planning a perimeter intrusion detection system, identifies the site characteristics that affect its performance, and describes improvements to perimeter intrusion detection sensors and assessment devices that have been achieved by using integrated circuit technology.

  4. Recent advances in imaging technologies in dentistry

    PubMed Central

    Shah, Naseem; Bansal, Nikhil; Logani, Ajay

    2014-01-01

    Dentistry has witnessed tremendous advances in all its branches over the past three decades. With these advances, the need for more precise diagnostic tools, specially imaging methods, have become mandatory. From the simple intra-oral periapical X-rays, advanced imaging techniques like computed tomography, cone beam computed tomography, magnetic resonance imaging and ultrasound have also found place in modern dentistry. Changing from analogue to digital radiography has not only made the process simpler and faster but also made image storage, manipulation (brightness/contrast, image cropping, etc.) and retrieval easier. The three-dimensional imaging has made the complex cranio-facial structures more accessible for examination and early and accurate diagnosis of deep seated lesions. This paper is to review current advances in imaging technology and their uses in different disciplines of dentistry. PMID:25349663

  5. Space solar cell technology development - A perspective

    NASA Technical Reports Server (NTRS)

    Scott-Monck, J.

    1982-01-01

    The developmental history of photovoltaics is examined as a basis for predicting further advances to the year 2000. Transistor technology was the precursor of solar cell development. Terrestrial cells were modified for space through changes in geometry and size, as well as the use of Ag-Ti contacts and manufacture of a p-type base. The violet cell was produced for Comsat, and involved shallow junctions, new contacts, and an enhanced antireflection coating for better radiation tolerance. The driving force was the desire by private companies to reduce cost and weight for commercial satellite power supplies. Liquid phase epitaxial (LPE) GaAs cells are the latest advancement, having a 4 sq cm area and increased efficiency. GaAs cells are expected to be flight ready in the 1980s. Testing is still necessary to verify production techniques and the resistance to electron and photon damage. Research will continue in CVD cell technology, new panel technology, and ultrathin Si cells.

  6. Elderly people's interaction with advanced technology.

    PubMed

    Blažun, Helena; Vošner, Janez; Kokol, Peter; Saranto, Kaija; Rissanen, Sari

    2014-01-01

    Aging of population is an inevitable process by which the number of elderly people is increasing. Rapid development of information and communication technology (ICT) is changing basic needs of elderly people; therefore society should ensure opportunities for elderly to learn and use ICT in a way to manage their daily life activities and in this way enable them participation in the information and knowledge society. The purpose of the study was to find out whether elderly are acquainted with the advanced technology and to what extent they use it or they desire to use it. Within the single point study we interviewed 100 randomly selected elderly people from different geographical regions in Slovenia. Results showed the differences in the use of advanced technology by Slovenian regions; therefore in the future activities should be focused on organizing promotional and demonstrational activities including ICT courses to increase elderly's motivation for ICT interaction.

  7. Overview of advanced law enforcement electronic technology

    NASA Astrophysics Data System (ADS)

    Harden, W. R.

    1995-05-01

    Law enforcement and security management are using advanced electronic equipment to increase the effectiveness and efficiency of the budget restricted police officer force. Currently there is also significant national attention concerning the possible utilization of 'military' electronic hardware to implement the much sought after 'force multiplier' which can help to alleviate each jurisdictions economic restrictions. However, as we are now finding, the transfer of 'military' hardware for utilization by law enforcement personnel is not as economically viable as hoped. This paper will address some of the recent advances in electronic technology that are being derived from the military technology base. Additionally, comments are given concerning the economic impact as the technology is transferred to the law enforcement community.

  8. ESA's advanced relay and technology mission

    NASA Astrophysics Data System (ADS)

    Lechte, H.; Bird, A. G.; van Holtz, L.; Oppenhauser, G.

    1990-05-01

    The Advanced Relay and Technology Mission is discussed. The objective of the mission is to develop, launch, and operate a single geostationary satellite. The proposed satellite includes advanced communications payloads with data-relay, mobile, and fixed-service applications. The semiconductor laser intersatellite link experiment (Silex), which is aimed at developing an optical communications data-relay system, is described. The Silex configuration is designed for LEO or GEO applications and has a 65 Mbit/s data rate over the optical return link. Consideration is given to the phased-array technology utilized in the S-band data-relay payload; the L-band land mobile payload; diagnostics and propagation packages; and technology experiments for improving the platform.

  9. The reprogramming therapy for a patient with advanced hepatocellular carcinoma by using human-induced pluripotent stem (iPS) cells technology.

    PubMed

    Moriguchi, Hisashi; Madson, Joren

    2013-01-01

    Therapeutic methods to reprogramme and destroy human solid tumour cells have not been developed. We show a proof-of-concept for the direct reprogramming therapy of human solid tumour cells. Furthermore, our study is the first to report on the development of a new treatment by using human-induced pluripotent stem cells technology.

  10. Advanced coal technology by-products: Long-term results from landfill test cells and their implications for reuse or disposal applications

    SciTech Connect

    Weinberg, A.; Harness, J.L.

    1994-06-01

    New air pollution regulations under the 1991 Clean Air Act and other legislation are motivating continued development and implementation, of cleaner, more efficient processes for converting coal to electrical power. These clean coal processes produce solid by-products which differ in important respects from conventional pulverized coal combustion ash. Clean coal by-products` contain both residual sorbent and captured SO{sub 2} control products, as well as the mineral component of the coal. The Department of Energy/Morgantown Energy Technology Center has contracted Radian Corporation to construct and monitor landfill test cells with a several different advanced coal combustion by-products at three locations around the US; data from these sites provide a unique picture of the long-term field behavior of clean coal combustion by-products. The field testing sites were located in western Colorado, northern Ohio, and central Illinois. Fluidized bed combustion and lime injection residues are characterized by high lime and calcium sulfate contents` contributed by reacted and unreacted sorbent materials, and produce an leachate, when wetted. Compared with conventional coal fly ash, the clean coal technology ashes have been noted for potential difficulties when wetted, including corrosivity, heat generation, cementation, and swelling on hydration. On the other hand, the high lime content and chemical reactivity of clean coal residues offer potential benefits in reuse as a cementitious material.The results of three years of data collection suggest a fairly consistent pattern of behavior for the calcium-based dry sorbent systems involved in the project, despite differences in the initial of the by-products, differences in the methods of placement, and differences in climate at the test sites.

  11. Sustainability assessment of advanced wastewater treatment technologies.

    PubMed

    Høibye, L; Clauson-Kaas, J; Wenzel, H; Larsen, H F; Jacobsen, B N; Dalgaard, O

    2008-01-01

    As a consequence of the EU Water Framework Directive more focus is now on discharges of hazardous substances from wastewater treatment plants and sewers. Thus, many municipalities in Denmark may have to adopt to future advanced treatment technologies. This paper describes a holistic assessment, which includes technical, economical and environmental aspects. The technical and economical assessment is performed on 5 advanced treatment technologies: sand filtration, ozone treatment, UV exclusively for disinfection of pathogenic microorganisms, membrane bioreactor (MBR) and UV in combination with advanced oxidation. The technical assessment is based on 12 hazardous substances comprising heavy metals, organic pollutants, endocrine disruptors as well as pathogenic microorganisms. The environmental assessment is performed by life cycle assessment (LCA) comprising 9 of the specific hazardous substances and three advanced treatment methods; sand filtration, ozone treatment and MBR. The technical and economic assessment showed that UV solely for disinfection purposes or ozone treatment is the most advantageous advanced treatment methods if the demands are restricted to pathogenic microorganisms. In terms of sustainability, sand filtration is the most advantageous method based on the technical and environmental assessment due to the low energy consumption and high efficiency with regards to removal of heavy metals.

  12. Advances in Bioprinting Technologies for Craniofacial Reconstruction.

    PubMed

    Visscher, Dafydd O; Farré-Guasch, Elisabet; Helder, Marco N; Gibbs, Susan; Forouzanfar, Tymour; van Zuijlen, Paul P; Wolff, Jan

    2016-09-01

    Recent developments in craniofacial reconstruction have shown important advances in both the materials and methods used. While autogenous tissue is still considered to be the gold standard for these reconstructions, the harvesting procedure remains tedious and in many cases causes significant donor site morbidity. These limitations have subsequently led to the development of less invasive techniques such as 3D bioprinting that could offer possibilities to manufacture patient-tailored bioactive tissue constructs for craniofacial reconstruction. Here, we discuss the current technological and (pre)clinical advances of 3D bioprinting for use in craniofacial reconstruction and highlight the challenges that need to be addressed in the coming years.

  13. Advances in Bioprinting Technologies for Craniofacial Reconstruction.

    PubMed

    Visscher, Dafydd O; Farré-Guasch, Elisabet; Helder, Marco N; Gibbs, Susan; Forouzanfar, Tymour; van Zuijlen, Paul P; Wolff, Jan

    2016-09-01

    Recent developments in craniofacial reconstruction have shown important advances in both the materials and methods used. While autogenous tissue is still considered to be the gold standard for these reconstructions, the harvesting procedure remains tedious and in many cases causes significant donor site morbidity. These limitations have subsequently led to the development of less invasive techniques such as 3D bioprinting that could offer possibilities to manufacture patient-tailored bioactive tissue constructs for craniofacial reconstruction. Here, we discuss the current technological and (pre)clinical advances of 3D bioprinting for use in craniofacial reconstruction and highlight the challenges that need to be addressed in the coming years. PMID:27113634

  14. Maneuvering technology for advanced fighter aircraft

    NASA Technical Reports Server (NTRS)

    Alexander, Michael G.; Harris, Scott H.; Byers, Richard H.

    1992-01-01

    The need for increased maneuverability has its genesis from the first aerial combat engagement when two adversaries entangled themselves in a deadly aerial dance trying to gain the advantage over the other. It has only been in the past two decades that technologies have been investigated to increase aircraft control at maneuver attitudes that are typically dominated by highly separated flows. These separated flow regions are aggravated by advanced fighter aircraft shapes required to defeat an electronic enemy. This paper discusses passive and active devices that can be used to enhance the maneuverability of advanced fighter aircraft through vortex flow control, boundary layer control, and innovative flow manipulation.

  15. Advanced endoscopic technologies for colorectal cancer screening

    PubMed Central

    Obstein, Keith L; Valdastri, Pietro

    2013-01-01

    Colorectal cancer is the third most common cancer in men and the second most common cancer in women worldwide. Diagnosing colorectal has been increasingly successful due to advances in technology. Flexible endoscopy is considered to be an effective method for early diagnosis and treatment of gastrointestinal cancer, making it a popular choice for screening programs. However, millions of people who may benefit from endoscopic colorectal cancer screening fail to have the procedure performed. Main reasons include psychological barriers due to the indignity of the procedure, fear of procedure related pain, bowel preparation discomfort, and potential need for sedation. Therefore, an urgent need for new technologies addressing these issues clearly exists. In this review, we discuss a set of advanced endoscopic technologies for colorectal cancer screening that are either already available or close to clinical trial. In particular, we focus on visual-inspection-only advanced flexible colonoscopes, interventional colonoscopes with alternative propulsion mechanisms, wireless capsule colonoscopy, and technologies for intraprocedural bowel cleansing. Many of these devices have the potential to reduce exam related patient discomfort, obviate the need for sedation, increase diagnostic yield, reduce learning curves, improve access to screening, and possibly avert the need for a bowel preparation. PMID:23382621

  16. An assessment of advanced technology for industrial cogeneration

    NASA Technical Reports Server (NTRS)

    Moore, N.

    1983-01-01

    The potential of advanced fuel utilization and energy conversion technologies to enhance the outlook for the increased use of industrial cogeneration was assessed. The attributes of advanced cogeneration systems that served as the basis for the assessment included their fuel flexibility and potential for low emissions, efficiency of fuel or energy utilization, capital equipment and operating costs, and state of technological development. Over thirty advanced cogeneration systems were evaluated. These cogeneration system options were based on Rankine cycle, gas turbine engine, reciprocating engine, Stirling engine, and fuel cell energy conversion systems. The alternatives for fuel utilization included atmospheric and pressurized fluidized bed combustors, gasifiers, conventional combustion systems, alternative energy sources, and waste heat recovery. Two advanced cogeneration systems with mid-term (3 to 5 year) potential were found to offer low emissions, multi-fuel capability, and a low cost of producing electricity. Both advanced cogeneration systems are based on conventional gas turbine engine/exhaust heat recovery technology; however, they incorporate advanced fuel utilization systems.

  17. The Importance of Advancing Technology to America's Energy Goals

    SciTech Connect

    Wilbanks, Thomas J; Greene, David L

    2010-05-01

    A wide range of energy technologies appears to be needed for the United States to meet its energy goals. A method is developed that relates the uncertainty of technological progress in eleven technology areas to the achievement of CO2 mitigation and reduced oil dependence. We conclude that to be confident of meeting both energy goals, each technology area must have a much better than 50/50 probability of success, that carbon capture and sequestration, biomass, battery electric or fuel cell vehicles, advanced fossil liquids, and energy efficiency technologies for buildings appear to be almost essential, and that the success of each one of the 11 technologies is important. These inferences are robust to moderate variations in assumptions.

  18. Advanced control technology and its potential for future transport aircraft

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.

  19. Advances in Robotic Servicing Technology Development

    NASA Technical Reports Server (NTRS)

    Gefke, Gardell G.; Janas, Alex; Pellegrino, Joseph; Sammons, Matthew; Reed, Benjamin

    2015-01-01

    NASA's Satellite Servicing Capabilities Office (SSCO) has matured robotic and automation technologies applicable to in-space robotic servicing and robotic exploration over the last six years. This paper presents the progress of technology development activities at the Goddard Space Flight Center Servicing Technology Center and on the ISS, with an emphasis on those occurring in the past year. Highlighted advancements are design reference mission analysis for servicing in low Earth orbit (LEO) and asteroid redirection; delivery of the engineering development unit of the NASA Servicing Arm; an update on International Space Station Robotic Refueling Mission; and status of a comprehensive ground-based space robot technology demonstration expanding in-space robotic servicing capabilities beginning fall 2015.

  20. Advances in Robotic Servicing Technology Development

    NASA Technical Reports Server (NTRS)

    Gefke, Gardell G.; Janas, Alex; Pellegrino, Joseph; Sammons, Matthew; Reed, Benjamin

    2015-01-01

    NASA's Satellite Servicing Capabilities Office (SSCO) has matured robotic and automation technologies applicable to in-space robotic servicing and robotic exploration over the last six years. This paper presents the progress of technology development activities at the Goddard Space Flight Center Servicing Technology Center and on the ISS, with an emphasis on those occurring in the past year. Highlighted advancements are design reference mission analysis for servicing in low Earth orbit (LEO) and near Earth asteroid boulder retrieval; delivery of the engineering development unit of the NASA Servicing Arm; an update on International Space Station Robotic Refueling Mission; and status of a comprehensive ground-based space robot technology demonstration expanding in-space robotic servicing capabilities beginning fall 2015.

  1. Ceramic technology for advanced heat engines project

    SciTech Connect

    Not Available

    1990-09-01

    The Ceramic Technology for Advanced Heat Engines Project was developed by the Department of Energy's Office of Transportation Systems in Conservation and Renewable Energy. This project was developed to meet the ceramic technology requirements of the OTT's automotive technology programs. This project is managed by ORNL and is closely coordinated with complementary ceramics tasks funded by other DOE offices, NASA, DoD, and industry. Research is discussed under the following topics; Turbomilling of SiC Whiskers; microwave sintering of silicon nitride; and milling characterization; processing of monolithics; silicon nitride matrix; oxide matrix; silicate matrix; thermal and wear coatings; joining; design; contact interfaces; time-dependent behavior; environmental effects; fracture mechanics; nondestructive evaluation; and technology transfer. References, figures, and tables are included with each topic.

  2. Pazopanib for the first-line treatment of patients with advanced and/or metastatic renal cell carcinoma : a NICE single technology appraisal.

    PubMed

    Kilonzo, Mary; Hislop, Jenni; Elders, Andrew; Fraser, Cynthia; Bissett, Donald; McClinton, Samuel; Mowatt, Graham; Vale, Luke

    2013-01-01

    The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of pazopanib hydrochloride (GlaxoSmithKline) to submit evidence of the clinical and cost effectiveness of the drug for the first-line treatment of advanced and/or metastatic renal cell carcinoma, as part of the Institute's single technology appraisal (STA) process. The Aberdeen Health Technology Assessment Group were commissioned to act as the Evidence Review Group (ERG). This article provides a description of the company submission, the ERG review and NICE's subsequent decisions. The objective of this paper is to summarize the independent review and critique of the evidence submitted for the consideration of the NICE Appraisal Committee and NICE's subsequently issued guidance. The ERG produced a critical review of the evidence for the clinical and cost effectiveness of the technology based upon the manufacturer's submission to NICE. The ERG also independently searched for relevant evidence and modified the manufacturer's decision analytic model to examine the impact of altering some of the key assumptions. For progression-free survival (PFS), there was a statistically significant longer survival for pazopanib compared with placebo (as assessed by the ERG, based upon the original manufacturer submission with a clinical cut-off date of 23 May 2008) [median 11.1 vs. 2.8 months; hazard ratio (HR) 0.40; 95 % CI 0.27, 0.60]. Data from the indirect comparison suggested that pazopanib had a greater survival than interferon alpha (IFN-α) [HR 0.512; 95 % CI 0.326, 0.802] but provided no evidence of any difference compared with sunitinib (HR 0.949; 95 % CI 0.575, 1.568). With regard to overall survival, 64 % (n = 99) of patients in the pazopanib arm and 63 % (n = 49) of patients in the placebo arm had died and a total of 51 % (n = 40) of placebo patients had crossed over to receive pazopanib. Although data were provided on an intention-to-treat basis, crossover between therapies

  3. Energy and cost saving results for advanced technology systems from the Cogeneration Technology Alternatives Study (CTAS)

    NASA Technical Reports Server (NTRS)

    Sagerman, G. D.; Barna, G. J.; Burns, R. K.

    1979-01-01

    An overview of the organization and methodology of the Cogeneration Technology Alternatives Study is presented. The objectives of the study were to identify the most attractive advanced energy conversion systems for industrial cogeneration applications in the future and to assess the advantages of advanced technology systems compared to those systems commercially available today. Advanced systems studied include steam turbines, open and closed cycle gas turbines, combined cycles, diesel engines, Stirling engines, phosphoric acid and molten carbonate fuel cells and thermionics. Steam turbines, open cycle gas turbines, combined cycles, and diesel engines were also analyzed in versions typical of today's commercially available technology to provide a base against which to measure the advanced systems. Cogeneration applications in the major energy consuming manufacturing industries were considered. Results of the study in terms of plant level energy savings, annual energy cost savings and economic attractiveness are presented for the various energy conversion systems considered.

  4. Advances and trends in computational structures technology

    NASA Technical Reports Server (NTRS)

    Noor, A. K.; Venneri, S. L.

    1990-01-01

    The major goals of computational structures technology (CST) are outlined, and recent advances in CST are examined. These include computational material modeling, stochastic-based modeling, computational methods for articulated structural dynamics, strategies and numerical algorithms for new computing systems, multidisciplinary analysis and optimization. The role of CST in the future development of structures technology and the multidisciplinary design of future flight vehicles is addressed, and the future directions of CST research in the prediction of failures of structural components, the solution of large-scale structural problems, and quality assessment and control of numerical simulations are discussed.

  5. Advanced Sciences and Technology Research for Astrodynamics

    NASA Astrophysics Data System (ADS)

    Jah, M.

    The Advanced Sciences and Technology Research Institute for Astrodynamics (ASTRIA) has been created as a research endeavor that focuses all astrodynamics R&D within the Air Force Research Laboratory (AFRL). ASTRIA is mainly a consortium of academic partners brought together to bear on the nation's challenges as related to astrodynamics sciences and technologies. An overview of ASTRIA is presented as well as examples of several research efforts that are relevant to data/track association, UCT/cross-tagging mitigation, and attitude recovery from light curve data.

  6. Second NASA Advanced Composites Technology Conference

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr. (Compiler); Bohon, Herman L. (Compiler)

    1992-01-01

    The conference papers are presented. The Advanced Composite Technology (ACT) Program is a major multi-year research initiative to achieve a national goal of technology readiness before the end of the decade. Conference papers recorded results of research in the ACT Program in the specific areas of automated fiber placement, resin transfer molding, textile preforms, and stitching as these processes influence design, performance, and cost of composites in aircraft structures. These papers will also be included in the Ninth Conference Proceedings to be published by the Federal Aviation Administration as a separate document.

  7. Advances in computed tomography imaging technology.

    PubMed

    Ginat, Daniel Thomas; Gupta, Rajiv

    2014-07-11

    Computed tomography (CT) is an essential tool in diagnostic imaging for evaluating many clinical conditions. In recent years, there have been several notable advances in CT technology that already have had or are expected to have a significant clinical impact, including extreme multidetector CT, iterative reconstruction algorithms, dual-energy CT, cone-beam CT, portable CT, and phase-contrast CT. These techniques and their clinical applications are reviewed and illustrated in this article. In addition, emerging technologies that address deficiencies in these modalities are discussed.

  8. Advanced rotorcraft technology: Task force report

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The technological needs and opportunities related to future civil and military rotorcraft were determined and a program plan for NASA research which was responsive to the needs and opportunities was prepared. In general, the program plan places the primary emphasis on design methodology where the development and verification of analytical methods is built upon a sound data base. The four advanced rotorcraft technology elements identified are aerodynamics and structures, flight control and avionic systems, propulsion, and vehicle configurations. Estimates of the total funding levels that would be required to support the proposed program plan are included.

  9. Personnel screening with advanced multistatic imaging technology

    NASA Astrophysics Data System (ADS)

    Ahmed, Sherif S.

    2013-05-01

    Personnel screening is demanded nowadays for securing air traffic as well as critical infrastructures. The millimeter-waves are able to penetrate clothes and detect concealed objects, making them an attractive choice for security screening. Imaging methods based on multistatic architecture can ensure high quality imagery in terms of resolution and dynamic range. Following the advances in semiconductor technology, fully electronic solutions delivering real-time imaging are becoming feasible. Furthermore, the continuously increasing capabilities of digital signal processing units allow for the utilization of digital-beamforming techniques for image reconstruction, thus offering new opportunities for imaging systems to use sophisticated operation modes. Based on these modern technologies, an advanced realization addressing personnel screening in E-band with planar multistatic sparse array design is demonstrated.

  10. Advanced manufacturing: Technology and international competitiveness

    SciTech Connect

    Tesar, A.

    1995-02-01

    Dramatic changes in the competitiveness of German and Japanese manufacturing have been most evident since 1988. All three countries are now facing similar challenges, and these challenges are clearly observed in human capital issues. Our comparison of human capital issues in German, Japanese, and US manufacturing leads us to the following key judgments: Manufacturing workforces are undergoing significant changes due to advanced manufacturing technologies. As companies are forced to develop and apply these technologies, the constituency of the manufacturing workforce (especially educational requirements, contingent labor, job content, and continuing knowledge development) is being dramatically and irreversibly altered. The new workforce requirements which result due to advanced manufacturing require a higher level of worker sophistication and responsibility.

  11. Advanced pyrochemical technologies for minimizing nuclear waste

    SciTech Connect

    Bronson, M.C.; Dodson, K.E.; Riley, D.C.

    1994-06-01

    The Department of Energy (DOE) is seeking to reduce the size of the current nuclear weapons complex and consequently minimize operating costs. To meet this DOE objective, the national laboratories have been asked to develop advanced technologies that take uranium and plutonium, from retired weapons and prepare it for new weapons, long-term storage, and/or final disposition. Current pyrochemical processes generate residue salts and ceramic wastes that require aqueous processing to remove and recover the actinides. However, the aqueous treatment of these residues generates an estimated 100 liters of acidic transuranic (TRU) waste per kilogram of plutonium in the residue. Lawrence Livermore National Laboratory (LLNL) is developing pyrochemical techniques to eliminate, minimize, or more efficiently treat these residue streams. This paper will present technologies being developed at LLNL on advanced materials for actinide containment, reactors that minimize residues, and pyrochemical processes that remove actinides from waste salts.

  12. Recent technological advancements in breast ultrasound.

    PubMed

    Eisenbrey, John R; Dave, Jaydev K; Forsberg, Flemming

    2016-08-01

    Ultrasound is becoming increasingly common as an imaging tool for the detection and characterization of breast tumors. This paper provides an overview of recent technological advancements, especially those that may have an impact in clinical applications in the field of breast ultrasound in the near future. These advancements include close to 100% fractional bandwidth high frequency (5-18MHz) 2D and 3D arrays, automated breast imaging systems to minimize the operator dependence and advanced processing techniques, such as those used for detection of microcalcifications. In addition, elastography and contrast-enhanced ultrasound examinations that are expected to further enhance the clinical importance of ultrasound based breast tumor screening are briefly reviewed. These techniques have shown initial promise in clinical trials and may translate to more comprehensive clinical adoption in the future.

  13. Recent technological advancements in breast ultrasound.

    PubMed

    Eisenbrey, John R; Dave, Jaydev K; Forsberg, Flemming

    2016-08-01

    Ultrasound is becoming increasingly common as an imaging tool for the detection and characterization of breast tumors. This paper provides an overview of recent technological advancements, especially those that may have an impact in clinical applications in the field of breast ultrasound in the near future. These advancements include close to 100% fractional bandwidth high frequency (5-18MHz) 2D and 3D arrays, automated breast imaging systems to minimize the operator dependence and advanced processing techniques, such as those used for detection of microcalcifications. In addition, elastography and contrast-enhanced ultrasound examinations that are expected to further enhance the clinical importance of ultrasound based breast tumor screening are briefly reviewed. These techniques have shown initial promise in clinical trials and may translate to more comprehensive clinical adoption in the future. PMID:27179143

  14. Development of Advanced Ceramic Manufacturing Technology

    SciTech Connect

    Pujari, V.K.

    2001-04-05

    Advanced structural ceramics are enabling materials for new transportation engine systems that have the potential for significantly reducing energy consumption and pollution in automobiles and heavy vehicles. Ceramic component reliability and performance have been demonstrated in previous U.S. DOE initiatives, but high manufacturing cost was recognized as a major barrier to commercialization. Norton Advanced Ceramics (NAC), a division of Saint-Gobain Industrial Ceramics, Inc. (SGIC), was selected to perform a major Advanced Ceramics Manufacturing Technology (ACMT) Program. The overall objectives of NAC's program were to design, develop, and demonstrate advanced manufacturing technology for the production of ceramic exhaust valves for diesel engines. The specific objectives were (1) to reduce the manufacturing cost by an order of magnitude, (2) to develop and demonstrate process capability and reproducibility, and (3) to validate ceramic valve performance, durability, and reliability. The program was divided into four major tasks: Component Design and Specification, Component Manufacturing Technology Development, Inspection and Testing, and Process Demonstration. A high-power diesel engine valve for the DDC Series 149 engine was chosen as the demonstration part for this program. This was determined to be an ideal component type to demonstrate cost-effective process enhancements, the beneficial impact of advanced ceramics on transportation systems, and near-term commercialization potential. The baseline valve material was NAC's NT451 SiAION. It was replaced, later in the program, by an alternate silicon nitride composition (NT551), which utilized a lower cost raw material and a simplified powder-processing approach. The material specifications were defined based on DDC's engine requirements, and the initial and final component design tasks were completed.

  15. Advanced Solar Cells for Satellite Power Systems

    NASA Technical Reports Server (NTRS)

    Flood, Dennis J.; Weinberg, Irving

    1994-01-01

    The multiple natures of today's space missions with regard to operational lifetime, orbital environment, cost and size of spacecraft, to name just a few, present such a broad range of performance requirements to be met by the solar array that no single design can suffice to meet them all. The result is a demand for development of specialized solar cell types that help to optimize overall satellite performance within a specified cost range for any given space mission. Historically, space solar array performance has been optimized for a given mission by tailoring the features of silicon solar cells to account for the orbital environment and average operating conditions expected during the mission. It has become necessary to turn to entirely new photovoltaic materials and device designs to meet the requirements of future missions, both in the near and far term. This paper will outline some of the mission drivers and resulting performance requirements that must be met by advanced solar cells, and provide an overview of some of the advanced cell technologies under development to meet them. The discussion will include high efficiency, radiation hard single junction cells; monolithic and mechanically stacked multiple bandgap cells; and thin film cells.

  16. Man-machine interface requirements - advanced technology

    NASA Technical Reports Server (NTRS)

    Remington, R. W.; Wiener, E. L.

    1984-01-01

    Research issues and areas are identified where increased understanding of the human operator and the interaction between the operator and the avionics could lead to improvements in the performance of current and proposed helicopters. Both current and advanced helicopter systems and avionics are considered. Areas critical to man-machine interface requirements include: (1) artificial intelligence; (2) visual displays; (3) voice technology; (4) cockpit integration; and (5) pilot work loads and performance.

  17. Medical technology advances from space research

    NASA Technical Reports Server (NTRS)

    Pool, S. L.

    1972-01-01

    Details of medical research and development programs, particularly an integrated medical laboratory, as derived from space technology are given. The program covers digital biotelemetry systems, automatic visual field mapping equipment, sponge electrode caps for clinical electroencephalograms, and advanced respiratory analysis equipment. The possibility of using the medical laboratory in ground based remote areas and regional health care facilities, as well as long duration space missions is discussed.

  18. Advanced technologies for future environmental satellite systems

    NASA Astrophysics Data System (ADS)

    Dittberner, Gerald J.; Crison, Michael J.; Bajpai, Shyam; Diedrich, Benjamin L.

    2004-09-01

    Environmental satellites today are designed to meet the most requirements possible within the constraints of budget, reliability, availability, robustness, manufacturability, and the state of the art in affordable technology. As we learn more and more about observing and forecasting, requirements continue to be developed and validated for measurements that can benefit from for advances in technology. The goal is to incorporate new technologies into operational systems as quickly as possible. Technologies that exist or are being developed in response to growing requirements can be categorized as "requirements pull" whereas technologies rooted in basic research and engineering exploration fall in to a "technology push" category. NOAA has begun exploration into technologies for future NOAA satellite systems. Unmet requirements exist that drive the need to locate, explore, exploit, assess, and encourage development in several technologies. Areas needing advanced technologies include: atmospheric aerosols; cloud parameters; precipitation; profiles of temperature, moisture, pressure, and wind; atmospheric radiation; trace gas abundance and distribution; land surface; ocean surface; and space weather components such as neutral density and electron density. One of the more interesting ideas in the technology push category is a constellation of satellites at Medium Earth Orbit (MEO) altitudes, here described as circular orbits near 11,000 km altitude. Consider the vision of being able to observe the environment anywhere on the Earth, at anytime, with any repeat look frequency, and being able to communicate these measurements to anyone, anywhere, anytime, in real time. Studies suggest that a constellation of MEO satellites occupying equatorial and polar orbits (inclination = 90 degrees) could, in principle, accomplish this task. Also new on the horizon is solar sail technology. NOAA has been looking at solar sails as providing a propulsive system that could be used to

  19. RUBIN Microsatellites for Advanced Space Technology Demonstration

    NASA Astrophysics Data System (ADS)

    Kalnins, Indulis

    The first new space technology demonstration payload BIRD-RUBIN was developed by OHB- System in co-operation with students from the University of Applied Sciences, Bremen, and was successfully launched July 15th, 2000 together with the scientific satellites CHAMP and MITA onboard a COSMOS 3M launcher. The BIRD-RUBIN mission has tested the telematics technology in space via ORBCOMM network. Small data packages were sent by the hatbox sized system to the ORBCOMM satellite net, then transmitted further on to the ground stations and from that point entered into the internet. The payload user could retrieve the data direct via email account and was able to send commands back to payload in orbit. The next micro satellite RUBIN-2 for advanced space technology demonstration will be launched at the end of 2002 as "secondary" payload on the Russian launcher DNEPR. The RUBIN-2 micro satellite platform will use again the inter-satellite communication mode via Orbcomm network and offers an orbital testbed with low cost, bi-directional and near real-time Internet access. In parallel to the further inter satellite link experiments using Orbcomm, several additional leading edge technology experiments will be done onboard Rubin-2 (electrical propulsion, two loop miniaturized thermal control system, GPS navigation, LI-Ion Battery, etc.). This paper provides an overview of RUBIN micro satellites for advanced space technology demonstrations. The main results of the first BIRD-RUBIN experiment and the goals of the second Rubin-2 mission are described. The potential of low cost technology demonstration missions using Internet and inter satellite communication technology via commercial satellite systems and the piggyback flight opportunities on Russian launchers are discussed.

  20. Advances in ambient temperature secondary lithium cells

    NASA Technical Reports Server (NTRS)

    Subbarao, S.; Shen, D. H.; Deligiannis, F.; Huang, C.-K.; Halpert, G.

    1990-01-01

    The goal of the NASA/OAST sponsored program on the development of ambient-temperature secondary lithium cells for future space applications is to develop cells with a 100 W h/kg specific energy and capable of 1000 cycles at 50-percent depth of discharge. This paper examines the performance potentials of Li-TiS2, Li-MoS3, Li-V6O13, and Li-NbSe3 electrochemical systems at ambient temperature, together with cycle life and safety characteristics. Of these four, the Li-TiS2 system was found to be the most promising in terms of achievable specific energy and cycle life. Major advances made on the development of secondary lithium cells, which are in the areas of cathode processing technology, mixed solvent electrolytes, and cell assembly, are summarized.

  1. Development of PEM fuel cell technology at international fuel cells

    SciTech Connect

    Wheeler, D.J.

    1996-04-01

    The PEM technology has not developed to the level of phosphoric acid fuel cells. Several factors have held the technology development back such as high membrane cost, sensitivity of PEM fuel cells to low level of carbon monoxide impurities, the requirement to maintain full humidification of the cell, and the need to pressurize the fuel cell in order to achieve the performance targets. International Fuel Cells has identified a hydrogen fueled PEM fuel cell concept that leverages recent research advances to overcome major economic and technical obstacles.

  2. Advanced Platform Systems Technology study. Volume 4: Technology advancement program plan

    NASA Technical Reports Server (NTRS)

    1983-01-01

    An overview study of the major technology definition tasks and subtasks along with their interfaces and interrelationships is presented. Although not specifically indicated in the diagram, iterations were required at many steps to finalize the results. The development of the integrated technology advancement plan was initiated by using the results of the previous two tasks, i.e., the trade studies and the preliminary cost and schedule estimates for the selected technologies. Descriptions for the development of each viable technology advancement was drawn from the trade studies. Additionally, a logic flow diagram depicting the steps in developing each technology element was developed along with descriptions for each of the major elements. Next, major elements of the logic flow diagrams were time phased, and that allowed the definition of a technology development schedule that was consistent with the space station program schedule when possible. Schedules show the major milestone including tests required as described in the logic flow diagrams.

  3. Advanced Reactor Technology -- Regulatory Technology Development Plan (RTDP)

    SciTech Connect

    Moe, Wayne Leland

    2015-05-01

    This DOE-NE Advanced Small Modular Reactor (AdvSMR) regulatory technology development plan (RTDP) will link critical DOE nuclear reactor technology development programs to important regulatory and policy-related issues likely to impact a “critical path” for establishing a viable commercial AdvSMR presence in the domestic energy market. Accordingly, the regulatory considerations that are set forth in the AdvSMR RTDP will not be limited to any one particular type or subset of advanced reactor technology(s) but rather broadly consider potential regulatory approaches and the licensing implications that accompany all DOE-sponsored research and technology development activity that deal with commercial non-light water reactors. However, it is also important to remember that certain “minimum” levels of design and safety approach knowledge concerning these technology(s) must be defined and available to an extent that supports appropriate pre-licensing regulatory analysis within the RTDP. Final resolution to advanced reactor licensing issues is most often predicated on the detailed design information and specific safety approach as documented in a facility license application and submitted for licensing review. Because the AdvSMR RTDP is focused on identifying and assessing the potential regulatory implications of DOE-sponsored reactor technology research very early in the pre-license application development phase, the information necessary to support a comprehensive regulatory analysis of a new reactor technology, and the resolution of resulting issues, will generally not be available. As such, the regulatory considerations documented in the RTDP should be considered an initial “first step” in the licensing process which will continue until a license is issued to build and operate the said nuclear facility. Because a facility license application relies heavily on the data and information generated by technology development studies, the anticipated regulatory

  4. Green Propulsion Technologies for Advanced Air Transports

    NASA Technical Reports Server (NTRS)

    Del Rosario, Ruben

    2015-01-01

    Air transportation is critical to U.S. and Global economic vitality. However, energy and climate issues challenge aviations ability to be sustainable in the long term. Aviation must dramatically reduce fuel use and related emissions. Energy costs to U.S. airlines nearly tripled between 1995 and 2011, and continue to be the highest percentage of operating costs. The NASA Advanced Air Transports Technology Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the NASA vision of revolutionary systems and propulsion technologies needed to achieve these challenging goals. Specifically, the primary focus is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe, which are envisioned as being powered by Hybrid Electric Propulsion Systems.

  5. RF Technologies for Advancing Space Communication Infrastructure

    NASA Technical Reports Server (NTRS)

    Romanofsky, Robert R.; Bibyk, Irene K.; Wintucky, Edwin G.

    2006-01-01

    This paper will address key technologies under development at the NASA Glenn Research Center designed to provide architecture-level impacts. Specifically, we will describe deployable antennas, a new type of phased array antenna and novel power amplifiers. The evaluation of architectural influence can be conducted from two perspectives where said architecture can be analyzed from either the top-down to determine the areas where technology improvements will be most beneficial or from the bottom-up where each technology s performance advancement can affect the overall architecture s performance. This paper will take the latter approach with focus on some technology improvement challenges and address architecture impacts. For example, using data rate as a performance metric, future exploration scenarios are expected to demand data rates possibly exceeding 1 Gbps. To support these advancements in a Mars scenario, as an example, Ka-band and antenna aperture sizes on the order of 10 meters will be required from Mars areostationary platforms. Key technical challenges for a large deployable antenna include maximizing the ratio of deployed-to-packaged volume, minimizing aerial density, maintaining RMS surface accuracy to within 1/20 of a wavelength or better, and developing reflector rigidization techniques. Moreover, the high frequencies and large apertures manifest a new problem for microwave engineers that are familiar to optical communications specialists: pointing. The fine beam widths and long ranges dictate the need for electronic or mechanical feed articulation to compensate for spacecraft attitude control limitations.

  6. Green Propulsion Technologies for Advanced Air Transports

    NASA Technical Reports Server (NTRS)

    Del Rosario, Ruben

    2015-01-01

    Air transportation is critical to U.S. and Global economic vitality. However, energy and climate issues challenge aviation's ability to be sustainable in the long term. Aviation must dramatically reduce fuel use and related emissions. Energy costs to U.S. airlines nearly tripled between 1995 and 2011, and continue to be the highest percentage of operating costs. The NASA Advanced Air Transports Technology Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the NASA vision of revolutionary systems and propulsion technologies needed to achieve these challenging goals. Specifically, the primary focus is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe.

  7. National Advanced Drilling and Excavation Technologies Program

    SciTech Connect

    1993-06-15

    The second meeting of Federal agency representatives interested in the National Advanced Drilling and Excavation Technologies (NADET) Program took place on June 15, 1993. The Geothermal Division of the U.S. Department of Energy (DOE) hosted the meeting at the Washington, D.C., offices of DOE. Representatives from the National Science Foundation, U.S. Geological Survey, U.S. Bureau of Mines, National Institute of Standards and Technology, National Aeronautics and Space Administration, Environmental Protection Agency, and various offices within the Department of Energy attended. For a complete list of attendees see Attachment A. The purpose of the meeting was: (1) to cover the status of efforts to gain formal approval for NADET, (2) to brief participants on events since the last meeting, especially two recent workshops that explored research needs in drilling and excavation, (3) to review some recent technological advances, and (4) to solicit statements of the importance of improving drilling and excavation technologies to the missions of the various agencies. The meeting agenda is included as Attachment B.

  8. Ceramic technology for Advanced Heat Engines Project

    SciTech Connect

    Johnson, D.R.

    1991-07-01

    Significant accomplishments in fabricating ceramic components for advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. However, these programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and database and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. An assessment of needs was completed, and a five year project plan was developed with extensive input from private industry. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on the structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines. To facilitate the rapid transfer of this technology to US industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities. This project is managed by ORNL for the Office of Transportation Technologies, Office of Transportation Materials, and is closely coordinated with complementary ceramics tasks funded by other DOE offices, NASA, DOD, and industry.

  9. Commercialization of Advanced Communications Technology Satellite (ACTS) technology

    NASA Astrophysics Data System (ADS)

    Plecity, Mark S.; Strickler, Walter M.; Bauer, Robert A.

    1996-03-01

    In an on-going effort to maintain United States leadership in communication satellite technology, the National Aeronautics and Space Administration (NASA), led the development of the Advanced Communications Technology Satellite (ACTS). NASA's ACTS program provides industry, academia, and government agencies the opportunity to perform both technology and telecommunication service experiments with a leading-edge communication satellite system. Over 80 organizations are using ACTS as a multi server test bed to establish communication technologies and services of the future. ACTS was designed to provide demand assigned multiple access (DAMA) digital communications with a minimum switchable circuit bandwidth of 64 Kbps, and a maximum channel bandwidth of 900 MHZ. It can, therefore, provide service to thin routes as well as connect fiber backbones in supercomputer networks, across oceans, or restore full communications in the event of national or manmade disaster. Service can also be provided to terrestrial and airborne mobile users. Commercial applications of ACTS technologies include: telemedicine; distance education; Department of Defense operations; mobile communications, aeronautical applications, terrestrial applications, and disaster recovery. This paper briefly describes the ACTS system and the enabling technologies employed by ACTS including Ka-band hopping spot beams, on-board routing and switching, and rain fade compensation. When used in conjunction with a time division multiple access (TDMA) architecture, these technologies provide a higher capacity, lower cost satellite system. Furthermore, examples of completed user experiments, future experiments, and plans of organizations to commercialize ACTS technology in their own future offerings will be discussed.

  10. Technology advancement of the static feed water electrolysis process

    NASA Technical Reports Server (NTRS)

    Schubert, F. H.; Wynveen, R. A.

    1977-01-01

    A program to advance the technology of oxygen- and hydrogen-generating subsystems based on water electrolysis was studied. Major emphasis was placed on static feed water electrolysis, a concept characterized by low power consumption and high intrinsic reliability. The static feed based oxygen generation subsystem consists basically of three subassemblies: (1) a combined water electrolysis and product gas dehumidifier module; (2) a product gas pressure controller and; (3) a cyclically filled water feed tank. Development activities were completed at the subsystem as well as at the component level. An extensive test program including single cell, subsystem and integrated system testing was completed with the required test support accessories designed, fabricated, and assembled. Mini-product assurance activities were included throughout all phases of program activities. An extensive number of supporting technology studies were conducted to advance the technology base of the static feed water electrolysis process and to resolve problems.

  11. Advanced thermal management technologies for defense electronics

    NASA Astrophysics Data System (ADS)

    Bloschock, Kristen P.; Bar-Cohen, Avram

    2012-05-01

    Thermal management technology plays a key role in the continuing miniaturization, performance improvements, and higher reliability of electronic systems. For the past decade, and particularly, the past 4 years, the Defense Advanced Research Projects Agency (DARPA) has aggressively pursued the application of micro- and nano-technology to reduce or remove thermal constraints on the performance of defense electronic systems. The DARPA Thermal Management Technologies (TMT) portfolio is comprised of five technical thrust areas: Thermal Ground Plane (TGP), Microtechnologies for Air-Cooled Exchangers (MACE), NanoThermal Interfaces (NTI), Active Cooling Modules (ACM), and Near Junction Thermal Transport (NJTT). An overview of the TMT program will be presented with emphasis on the goals and status of these efforts relative to the current State-of-the-Art. The presentation will close with future challenges and opportunities in the thermal management of defense electronics.

  12. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2004-05-12

    This Technical Progress Report describes progress made on the seventeen subprojects awarded in the first year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of project activity only. The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium--Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno--that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation (2) Solid-liquid separation (3) Chemical/Biological Extraction (4) Modeling and Control, and (5) Environmental Control.

  13. Advanced Fuel Cell System Thermal Management for NASA Exploration Missions

    NASA Technical Reports Server (NTRS)

    Burke, Kenneth A.

    2009-01-01

    The NASA Glenn Research Center is developing advanced passive thermal management technology to reduce the mass and improve the reliability of space fuel cell systems for the NASA exploration program. An analysis of a state-of-the-art fuel cell cooling systems was done to benchmark the portion of a fuel cell system s mass that is dedicated to thermal management. Additional analysis was done to determine the key performance targets of the advanced passive thermal management technology that would substantially reduce fuel cell system mass.

  14. Advanced Education and Technology Business Plan, 2010-13

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2010

    2010-01-01

    This paper presents the business plan of the Ministry of Advanced Education and Technology for 2010 to 2013. Advanced Education and Technology supports the advanced learning system by providing funding for advanced learning providers, coordinating and approving programs of study at public institutions, licensing and approving programs at private…

  15. Advanced spacecraft fuel cell systems

    NASA Technical Reports Server (NTRS)

    Thaller, L. H.

    1972-01-01

    The development and characteristics of advanced spacecraft fuel cell systems are discussed. The system is designed to operate on low pressure, propulsion grade hydrogen and oxygen. The specific goals are 10,000 hours of operation with refurbishment, 20 pounds per kilowatt at a sustained power of 7 KW, and 21 KW peaking capability for durations of two hours. The system rejects waste heat to the spacecraft cooling system at power levels up to 7 KW. At higher powers, the system automatically transfers to open cycle operation with overboard steam venting.

  16. 10 CFR 611.3 - Advanced technology vehicle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is...

  17. 10 CFR 611.3 - Advanced technology vehicle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is...

  18. 10 CFR 611.3 - Advanced technology vehicle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is...

  19. 10 CFR 611.3 - Advanced technology vehicle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is...

  20. 10 CFR 611.3 - Advanced technology vehicle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is...

  1. Technological Advances in Deep Brain Stimulation.

    PubMed

    Ughratdar, Ismail; Samuel, Michael; Ashkan, Keyoumars

    2015-01-01

    Functional and stereotactic neurosurgery has always been regarded as a subspecialty based on and driven by technological advances. However until recently, the fundamentals of deep brain stimulation (DBS) hardware and software design had largely remained stagnant since its inception almost three decades ago. Recent improved understanding of disease processes in movement disorders as well clinician and patient demands has resulted in new avenues of development for DBS technology. This review describes new advances both related to hardware and software for neuromodulation. New electrode designs with segmented contacts now enable sophisticated shaping and sculpting of the field of stimulation, potentially allowing multi-target stimulation and avoidance of side effects. To avoid lengthy programming sessions utilising multiple lead contacts, new user-friendly software allows for computational modelling and individualised directed programming. Therapy delivery is being improved with the next generation of smaller profile, longer-lasting, re-chargeable implantable pulse generators (IPGs). These include IPGs capable of delivering constant current stimulation or personalised closed-loop adaptive stimulation. Post-implantation Magnetic Resonance Imaging (MRI) has long been an issue which has been partially overcome with 'MRI conditional devices' and has enabled verification of DBS lead location. Surgical technique is considering a shift from frame-based to frameless stereotaxy or greater role for robot assisted implantation. The challenge for these contemporary techniques however, will be in demonstrating equivalent safety and accuracy to conventional methods. We also discuss potential future direction utilising wireless technology allowing for miniaturisation of hardware. PMID:26406128

  2. Technological Advances in Deep Brain Stimulation.

    PubMed

    Ughratdar, Ismail; Samuel, Michael; Ashkan, Keyoumars

    2015-01-01

    Functional and stereotactic neurosurgery has always been regarded as a subspecialty based on and driven by technological advances. However until recently, the fundamentals of deep brain stimulation (DBS) hardware and software design had largely remained stagnant since its inception almost three decades ago. Recent improved understanding of disease processes in movement disorders as well clinician and patient demands has resulted in new avenues of development for DBS technology. This review describes new advances both related to hardware and software for neuromodulation. New electrode designs with segmented contacts now enable sophisticated shaping and sculpting of the field of stimulation, potentially allowing multi-target stimulation and avoidance of side effects. To avoid lengthy programming sessions utilising multiple lead contacts, new user-friendly software allows for computational modelling and individualised directed programming. Therapy delivery is being improved with the next generation of smaller profile, longer-lasting, re-chargeable implantable pulse generators (IPGs). These include IPGs capable of delivering constant current stimulation or personalised closed-loop adaptive stimulation. Post-implantation Magnetic Resonance Imaging (MRI) has long been an issue which has been partially overcome with 'MRI conditional devices' and has enabled verification of DBS lead location. Surgical technique is considering a shift from frame-based to frameless stereotaxy or greater role for robot assisted implantation. The challenge for these contemporary techniques however, will be in demonstrating equivalent safety and accuracy to conventional methods. We also discuss potential future direction utilising wireless technology allowing for miniaturisation of hardware.

  3. The Advanced Technology Development Center (ATDC)

    NASA Technical Reports Server (NTRS)

    Clements, G. R.; Willcoxon, R. (Technical Monitor)

    2001-01-01

    NASA is building the Advanced Technology Development Center (ATDC) to provide a 'national resource' for the research, development, demonstration, testing, and qualification of Spaceport and Range Technologies. The ATDC will be located at Space Launch Complex 20 (SLC-20) at Cape Canaveral Air Force Station (CCAFS) in Florida. SLC-20 currently provides a processing and launch capability for small-scale rockets; this capability will be augmented with additional ATDC facilities to provide a comprehensive and integrated in situ environment. Examples of Spaceport Technologies that will be supported by ATDC infrastructure include densified cryogenic systems, intelligent automated umbilicals, integrated vehicle health management systems, next-generation safety systems, and advanced range systems. The ATDC can be thought of as a prototype spaceport where industry, government, and academia, in partnership, can work together to improve safety of future space initiatives. The ATDC is being deployed in five separate phases. Major ATDC facilities will include a Liquid Oxygen Area; a Liquid Hydrogen Area, a Liquid Nitrogen Area, and a multipurpose Launch Mount; 'Iron Rocket' Test Demonstrator; a Processing Facility with a Checkout and Control System; and Future Infrastructure Developments. Initial ATDC development will be completed in 2006.

  4. Advanced supersonic technology propulsion system study

    NASA Technical Reports Server (NTRS)

    Szeliga, R.; Allan, R. D.

    1974-01-01

    This study had the objectives of determining the most promising conventional and variable cycle engine types; the effect of design cruise Mach number (2.2, 2.7 and 3.2) on a commercial supersonic transport; effect of advanced engine technology on the choice of engine cycle; and effect of utilizing hydrogen as the engine fuel. The technology required for the engines was defined, and the levels of development to ensure availability of this technology in advanced aircraft propulsion systems were assessed. No clearcut best conventional or variable cycle engine was identified. The dry bypass turbojet and the duct burning turbofans were initially selected as the best conventional engines, but later results, utilizing augmentation at takeoff, added the mixed-flow augmented turbofan as a promising contender. The modulating air flow, three-rotor variable cycle engine identified the performance features desired from VCE concepts (elimination of inlet drag and reduction in afterbody drag), but was a very heavy and complex engine.

  5. IPIRG programs - advances in pipe fracture technology

    SciTech Connect

    Wilkowski, G.; Olson, R.; Scott, P.

    1997-04-01

    This paper presents an overview of the advances made in fracture control technology as a result of the research performed in the International Piping Integrity Research Group (IPIRG) program. The findings from numerous experiments and supporting analyses conducted to investigate the behavior of circumferentially flawed piping and pipe systems subjected to high-rate loading typical of seismic events are summarized. Topics to be discussed include; (1) Seismic loading effects on material properties, (2) Piping system behavior under seismic loads, (3) Advances in elbow fracture evaluations, and (4) {open_quotes}Real{close_quotes} piping system response. The presentation for each topic will be illustrated with data and analytical results. In each case, the state-of-the-art in fracture mechanics prior to the first IPIRG program will be contrasted with the state-of-the-art at the completion of the IPIRG-2 program.

  6. Technology readiness for advanced ducted engines

    SciTech Connect

    Eckardt, D.; Brines, G.L.

    1989-01-01

    The Advanced Ducted Engines (ADEs) currently undergoing development for next-generation passenger aircraft typically possess bypass ratios of the order of 12-25 and specific fuel consumption figures 12-17 percent lower than current advanced turbofans. An extensive technology-readiness program has been mounted on behalf of ADE design definition over the last two years, encompassing among its concerns aircraft/engine-installation interference, low pressure-ratio fan aerodynamics, fan/nacelle interactions (including windmilling and thrust-reversal), acoustic characteristics, transonic-drive turbines, and slender nacelle aerodynamic and mechanical design. Both turbine-driven and geared ADE fans, which may be of single-rotating or contrarotating type, are discussed. 5 refs.

  7. Laser light scattering instrument advanced technology development

    NASA Technical Reports Server (NTRS)

    Wallace, J. F.

    1993-01-01

    The objective of this advanced technology development (ATD) project has been to provide sturdy, miniaturized laser light scattering (LLS) instrumentation for use in microgravity experiments. To do this, we assessed user requirements, explored the capabilities of existing and prospective laser light scattering hardware, and both coordinated and participated in the hardware and software advances needed for a flight hardware instrument. We have successfully breadboarded and evaluated an engineering version of a single-angle glove-box instrument which uses solid state detectors and lasers, along with fiber optics, for beam delivery and detection. Additionally, we have provided the specifications and written verification procedures necessary for procuring a miniature multi-angle LLS instrument which will be used by the flight hardware project which resulted from this work and from this project's interaction with the laser light scattering community.

  8. Advanced Technology System Scheduling Governance Model

    SciTech Connect

    Ang, Jim; Carnes, Brian; Hoang, Thuc; Vigil, Manuel

    2015-06-11

    In the fall of 2005, the Advanced Simulation and Computing (ASC) Program appointed a team to formulate a governance model for allocating resources and scheduling the stockpile stewardship workload on ASC capability systems. This update to the original document takes into account the new technical challenges and roles for advanced technology (AT) systems and the new ASC Program workload categories that must be supported. The goal of this updated model is to effectively allocate and schedule AT computing resources among all three National Nuclear Security Administration (NNSA) laboratories for weapons deliverables that merit priority on this class of resource. The process outlined below describes how proposed work can be evaluated and approved for resource allocations while preserving high effective utilization of the systems. This approach will provide the broadest possible benefit to the Stockpile Stewardship Program (SSP).

  9. Recent advances in magnetostrictive particulate composite technology

    NASA Astrophysics Data System (ADS)

    Pulliam, Wade J.; McKnight, Geoffrey P.; Carman, Gregory P.

    2002-07-01

    Recently, there have been significant advances in using magnetostrictive particles in a polymer matrix; finding uses in many applications, both as an active transducer and a passive damper. Termed magnetostrictive particulate composites (MPC), the material provides capabilities identical or superior to the monolithic material. Fortis Technologies has been pursuing improvements in the application and fabrication of this innovative material. The MPC technology provides a passive, broadband, large temperature range, high stiffness, dampling material to be used where current technologies fall short. Damping applications of this technology include sporting goods, power/hand tools, space launch and satellite design, noise abatement and vibration isolation. Energy absorption of the composites has been measured and is approaching that of the monolithic material. The material can also be actively controlled by a magnetic field, producing a transducer that can be used for sonar applications. The advantage of this technology over those currently in use is the large power density at relatively low frequencies and the ease of fabrication, allowing less expensive and more effective conformal arrays. Effective strain output and piezomagnetic coefficients have been measured, as have its dynamic properties. The results show significant improvement of the strain output and piezomagnetic coefficients, approaching the monolithic material.

  10. Advanced Technology Development for Stirling Convertors

    NASA Technical Reports Server (NTRS)

    Thieme, Lanny G.; Schreiber, Jeffrey G.

    2004-01-01

    A high-efficiency Stirling Radioisotope Generator (SRG) for use on potential NASA Space Science missions is being developed by the Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center (GRC). These missions may include providing spacecraft onboard electric power for deep space missions or power for unmanned Mars rovers. GRC is also developing advanced technology for Stirling convertors, aimed at substantially improving the specific power and efficiency of the convertor and the overall power system. Performance and mass improvement goals have been established for second- and thirdgeneration Stirling radioisotope power systems. Multiple efforts are underway to achieve these goals, both in-house at GRC and under various grants and contracts. The status and results to date for these efforts will be discussed in this paper. Cleveland State University (CSU) is developing a multi-dimensional Stirling computational fluid dynamics code, capable of modeling complete convertors. A 2-D version of the code is now operational, and validation efforts at both CSU and the University of Minnesota are complementing the code development. A screening of advanced superalloy, refractory metal alloy, and ceramic materials has been completed, and materials have been selected for creep and joining characterization as part of developing a high-temperature heater head. A breadboard characterization is underway for an advanced controller using power electronics for active power factor control with a goal of eliminating the heavy tuning capacitors that are typically needed to achieve near unity power factors. Key Stirling developments just initiated under recent NRA (NASA Research Announcement) awards will also be discussed. These include a lightweight convertor to be developed by Sunpower Inc. and an advanced microfabricated regenerator to be done by CSU.

  11. Physics and Advanced Technologies 2001 Annual Report

    SciTech Connect

    Jacobs, R

    2002-05-09

    The Physics and Advanced Technologies (PAT) Directorate was created in July 2000 by Bruce Tarter, Director of Lawrence Livermore National Laboratory (LLNL). The Director called for the new organization to execute and support programs that apply cutting-edge physics and advanced technology to develop integrated solutions to problems in national security, fusion energy, information science, health care, and other national grand challenges. When I was appointed a year later as the PAT Directorate's first Associate Director, I initiated a strategic planning project to develop a vision, mission, and long-term goals for the Directorate. We adopted the goal of becoming a leader in frontier physics and technology for twenty-first-century national security missions: Stockpile Stewardship, homeland security, energy independence, and the exploration of space. Our mission is to: (1) Help ensure the scientific excellence and vitality of the major LLNL programs through its leadership role in performing basic and applied multidisciplinary research and development with programmatic impact, and by recruiting and retaining science and technology leaders; (2) Create future opportunities and directions for LLNL and its major programs by growing new program areas and cutting-edge capabilities that are synergistic with, and supportive of, its national security mission; (3) Provide a direct conduit to the academic and high-tech industrial sectors for LLNL and its national security programs, through which the Laboratory gains access to frontier science and technology, and can impact the science and technology communities; (4) Leverage unique Laboratory capabilities, to advance the state universe. This inaugural PAT Annual Report begins a series that will chronicle our progress towards fulfilling this mission. I believe the report demonstrates that the PAT Directorate has a strong base of capabilities and accomplishments on which to build in meeting its goals. Some of the highlights

  12. Management accounting for advanced technological environments.

    PubMed

    Kaplan, R S

    1989-08-25

    Management accounting systems designed decades ago no longer provide timely, relevant information for companies in today's highly competitive environment. New operational control and performance measurement systems are recognizing the importance of direct measurement of quality, manufacturing lead times, flexibility, and customer responsiveness, as well as more accurate measures of the actual costs of consumed resources. Activity-based cost systems can assign the costs of indirect and support resources to the specific products and activities that benefit from these resources. Both operational control and activity-based systems represent new opportunities for improved managerial information in complex, technologically advanced environments. PMID:17773356

  13. AGT (Advanced Gas Turbine) technology project

    NASA Technical Reports Server (NTRS)

    1988-01-01

    An overall summary documentation is provided for the Advanced Gas Turbine Technology Project conducted by the Allison Gas Turbine Division of General Motors. This advanced, high risk work was initiated in October 1979 under charter from the U.S. Congress to promote an engine for transportation that would provide an alternate to reciprocating spark ignition (SI) engines for the U.S. automotive industry and simultaneously establish the feasibility of advanced ceramic materials for hot section components to be used in an automotive gas turbine. As this program evolved, dictates of available funding, Government charter, and technical developments caused program emphases to focus on the development and demonstration of the ceramic turbine hot section and away from the development of engine and powertrain technologies and subsequent vehicular demonstrations. Program technical performance concluded in June 1987. The AGT 100 program successfully achieved project objectives with significant technology advances. Specific AGT 100 program achievements are: (1) Ceramic component feasibility for use in gas turbine engines has been demonstrated; (2) A new, 100 hp engine was designed, fabricated, and tested for 572 hour at operating temperatures to 2200 F, uncooled; (3) Statistical design methodology has been applied and correlated to experimental data acquired from over 5500 hour of rig and engine testing; (4) Ceramic component processing capability has progressed from a rudimentary level able to fabricate simple parts to a sophisticated level able to provide complex geometries such as rotors and scrolls; (5) Required improvements for monolithic and composite ceramic gas turbine components to meet automotive reliability, performance, and cost goals have been identified; (6) The combustor design demonstrated lower emissions than 1986 Federal Standards on methanol, JP-5, and diesel fuel. Thus, the potential for meeting emission standards and multifuel capability has been initiated

  14. Advanced Modulation and Coding Technology Conference

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The objectives, approach, and status of all current LeRC-sponsored industry contracts and university grants are presented. The following topics are covered: (1) the LeRC Space Communications Program, and Advanced Modulation and Coding Projects; (2) the status of four contracts for development of proof-of-concept modems; (3) modulation and coding work done under three university grants, two small business innovation research contracts, and two demonstration model hardware development contracts; and (4) technology needs and opportunities for future missions.

  15. Cell patterning technologies for organotypic tissue fabrication.

    PubMed

    Guillotin, Bertrand; Guillemot, Fabien

    2011-04-01

    Bottom-up tissue engineering technologies address two of the main limitations of top-down tissue engineering approaches: the control of mass transfer and the fabrication of a controlled and functional histoarchitecture. These emerging technologies encompass mesoscale (e.g. cell sheets, cell-laden hydrogels and 3D printing) and microscale technologies (e.g. inkjet printing and laser-assisted bioprinting), which are used to manipulate and assemble cell-laden building blocks whose thicknesses correspond to the diffusion limit of metabolites, and present the capacity for cell patterning with microscale precision, respectively. Here, we review recent technological advances and further discuss how these technologies are complementary, and could therefore be combined for the biofabrication of organotypic tissues either in vitro, thus serving as realistic tissue models, or within a clinic setting.

  16. Exploring the glycoproteomics landscape with advanced MS technologies.

    PubMed

    Lazar, Iulia M; Deng, Jingren; Ikenishi, Fumio; Lazar, Alexandru C

    2015-01-01

    The advance of glycoproteomic technologies has offered unique insights into the importance of glycosylation in determining the functional roles of a protein within a cell. Biologically active glycoproteins include the categories of enzymes, hormones, proteins involved in cell proliferation, cell membrane proteins involved in cell-cell recognition, and communication events or secreted proteins, just to name a few. The recent progress in analytical instrumentation, methodologies, and computational approaches has enabled a detailed exploration of glycan structure, connectivity, and heterogeneity, underscoring the staggering complexity of the glycome repertoire in a cell. A variety of approaches involving the use of spectroscopy, MS, separation, microfluidic, and microarray technologies have been used alone or in combination to tackle the glycoproteome challenge, the research results of these efforts being captured in an overwhelming number of annual publications. This work is aimed at reviewing the major developments and accomplishments in the field of glycoproteomics, with focus on the most recent advancements (2012-2014) that involve the use of capillary separations and MS detection. PMID:25311661

  17. AEDOT technology. [Advanced Energy Design and Operation Technologies (AEDOT)

    SciTech Connect

    Shankle, D.L.

    1993-03-01

    Most commercial buildings designed today will use more energy and cost more to operate and maintain than necessary. If energy performance were considered early in building design, 30% to 60% of the energy now used in new commercial buildings could be saved cost-effectively. However, most building design teams do not adequately consider the energy impacts of design decisions to achieve these savings; the tools for doing so simply do not yet exist. Computer technology can help design teams consider energy performance as an integral part of the design process. This technology could enable designers to produce much more energy-efficient buildings without increasing the costs of building design. Recognizing this, the US Department of Energy (DOE) has initiated the Advanced Energy Design and Operation Technologies (AEDOT) project, led by Pacific Northwest Laboratory (PNL). The aim of the project is to develop advanced computer-based technologies that will help designers take advantage of these potentially large energy savings. The success of the AEDOT project depends largely on the ability to develop energy design-support tools that can be integrated into comprehensive building design environments so that all parts of the design process willbe supported. Energy, just one consideration among many in building design, must be considered in a context that includes visual, acoustic, and structural aspects; accessibility; thermal comfort; indoor air quality; cost; and other factors associated with the quality, acceptability, and performance of a building. Advanced computer-aided design support environments will need to integrate tools from many different domains and provide access to the vast amounts of data that designers need to apply these tools and to make informed decisions.

  18. Advanced 3-V semiconductor technology assessment

    NASA Technical Reports Server (NTRS)

    Nowogrodzki, M.

    1983-01-01

    Components required for extensions of currently planned space communications systems are discussed for large antennas, crosslink systems, single sideband systems, Aerostat systems, and digital signal processing. Systems using advanced modulation concepts and new concepts in communications satellites are included. The current status and trends in materials technology are examined with emphasis on bulk growth of semi-insulating GaAs and InP, epitaxial growth, and ion implantation. Microwave solid state discrete active devices, multigigabit rate GaAs digital integrated circuits, microwave integrated circuits, and the exploratory development of GaInAs devices, heterojunction devices, and quasi-ballistic devices is considered. Competing technologies such as RF power generation, filter structures, and microwave circuit fabrication are discussed. The fundamental limits of semiconductor devices and problems in implementation are explored.

  19. Advanced teleoperation: Technology innovations and applications

    NASA Technical Reports Server (NTRS)

    Schenker, Paul S.; Bejczy, Antal K.; Kim, Won S.

    1994-01-01

    The capability to remotely, robotically perform space assembly, inspection, servicing, and science functions would rapidly expand our presence in space, and the cost efficiency of being there. There is considerable interest in developing 'telerobotic' technologies, which also have comparably important terrestrial applications to health care, underwater salvage, nuclear waste remediation and other. Such tasks, both space and terrestrial, require both a robot and operator interface that is highly flexible and adaptive, i.e., capable of efficiently working in changing and often casually structured environments. One systems approach to this requirement is to augment traditional teleoperation with computer assists -- advanced teleoperation. We have spent a number of years pursuing this approach, and highlight some key technology developments and their potential commercial impact. This paper is an illustrative summary rather than self-contained presentation; for completeness, we include representative technical references to our work which will allow the reader to follow up items of particular interest.

  20. Systematic Discrimination of Advanced Hydrogen Production Technologies

    SciTech Connect

    Charles V. Park; Michael W. Patterson

    2010-07-01

    The U.S. Department of Energy, in concert with industry, is developing a high-temperature gas-cooled reactor at the Idaho National Laboratory (INL) to demonstrate high temperature heat applications to produce hydrogen and electricity or to support other industrial applications. A key part of this program is the production of hydrogen from water that would significantly reduce carbon emissions compared to current production using natural gas. In 2009 the INL led the methodical evaluation of promising advanced hydrogen production technologies in order to focus future resources on the most viable processes. This paper describes how the evaluation process was systematically planned and executed. As a result, High-Temperature Steam Electrolysis was selected as the most viable near-term technology to deploy as a part of the Next Generation Nuclear Plant Project.

  1. CENTER FOR ADVANCED SEPARATION TECHNOLOGY (CAST) PROGRAM

    SciTech Connect

    Yoon, Roe-Hoan; Hull, Christopher

    2014-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations.

  2. Technologies Advance UAVs for Science, Military

    NASA Technical Reports Server (NTRS)

    2010-01-01

    A Space Act Agreement with Goddard Space Flight Center and West Virginia University enabled Aurora Flight Sciences Corporation, of Manassas, Virginia, to develop cost-effective composite manufacturing capabilities and open a facility in West Virginia. The company now employs 160 workers at the plant, tasked with crafting airframe components for the Global Hawk unmanned aerial vehicle (UAV) program. While one third of the company's workforce focuses on Global Hawk production, the rest of the company develops advanced UAV technologies that are redefining traditional approaches to unmanned aviation. Since the company's founding, Aurora s cutting-edge work has been supported with funding from NASA's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs.

  3. Recent advances in polyethylene separator technology

    NASA Astrophysics Data System (ADS)

    Weighall, M. J.

    The well known technical and production benefits of polyethylene separator materials over other separator materials have prompted a dramatic increase in polyethylene separator usage in recent years. Separator trends in the United States from 1980 to 1996, and in Europe from 1987 to 1992, are shown. The manufacturing process for polyethylene separators is outlined, with particular emphasis on the latest advances in manufacturing technology. These improvements have resulted in a higher quality product, and also benefit the environment because of the sophisticated oil extraction and solvent recovery system. The product quality improvements resulting from the latest manufacturing technology include consistent conformance to dimensional specifications, low electrical resistance, close control of residual oil content, virtual elimination of pinholes, and good running properties on the battery manufacturers' plate enveloping machines. The material can also be manufactured with a very thin backweb to reduce electrical resistance still further.

  4. Composite armored vehicle advanced technology demonstator

    SciTech Connect

    Ostberg, D.T.; Dunfee, R.S.; Thomas, G.E.

    1996-12-31

    Composite structures are a key technology needed to develop future lightweight combat vehicles that are both deployable and survivable. The Composite Armored Vehicle Advanced Technology Demonstrator Program that started in fiscal year 1994 will continue through 1998 to verily that composite structures are a viable solution for ground combat vehicles. Testing thus far includes material characterization, structural component tests and full scale quarter section tests. Material and manufacturing considerations, tests, results and changes, and the status of the program will be described. The structural component tests have been completed successfully, and quarter section testing is in progress. Upon completion of the critical design review, the vehicle demonstrator will be Fabricated and undergo government testing.

  5. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This report is the fifth in a series of Annual Technical Summary Reports for the Advanced Turbine Technology Applications Project (ATTAP), sponsored by the U.S. Department of Energy (DOE). The report was prepared by Garrett Auxiliary Power Division (GAPD), a unit of Allied-Signal Aerospace Company, a unit of Allied Signal, Inc. The report includes information provided by Garrett Ceramic Components, and the Norton Advanced Ceramics Company, (formerly Norton/TRW Ceramics), subcontractors to GAPD on the ATTAP. This report covers plans and progress on ceramics development for commercial automotive applications over the period 1 Jan. through 31 Dec. 1992. Project effort conducted under this contract is part of the DOE Gas Turbine Highway Vehicle System program. This program is directed to provide the U.S. automotive industry the high-risk, long-range technology necessary to produce gas turbine engines for automobiles with reduced fuel consumption, reduced environmental impact, and a decreased reliance on scarce materials and resources. The program is oriented toward developing the high-risk technology of ceramic structural component design and fabrication, such that industry can carry this technology forward to production in the 1990's. The ATTAP test bed engine, carried over from the previous AGT101 project, is being used for verification testing of the durability of next generation ceramic components, and their suitability for service at Reference Powertrain Design conditions. This document reports the technical effort conducted by GAPD and the ATTAP subcontractors during the fifth year of the project. Topics covered include ceramic processing definition and refinement, design improvements to the ATTAP test bed engine and test rigs, and the methodology development of ceramic impact and fracture mechanisms. Appendices include reports by ATTAP subcontractors in the development of silicon nitride materials and processes.

  6. [New advances in animal transgenic technology].

    PubMed

    Sun, Zhen-Hong; Miao, Xiang-Yang; Zhu, Rui-Liang

    2010-06-01

    Animal transgenic technology is one of the fastest growing biotechnology in the 21st century. It is used to integrate foreign genes into the animal genome by genetic engineering technology so that foreign genes can be expressed and inherited to the offspring. The transgenic efficiency and precise control of gene expression are the key limiting factors on preparation of transgenic animals. A variety of transgenic techniques are available, each of which has its own advantages and disadvantages and still needs further study because of unresolved technical and safety issues. With the in-depth research, the transgenic technology will have broad application prospects in the fields of exploration of gene function, animal genetic improvement, bioreactor, animal disease models, organ transplantation and so on. This article reviews the recently developed animal gene transfer techniques, including germline stem cell mediated method to improve the efficiency, gene targeting to improve the accuracy, RNA interference (RNAi)-mediated gene silencing technology, and the induced pluripotent stem cells (iPS) transgenic technology. The new transgenic techniques can provide a better platform for the study of trans-genic animals and promote the development of medical sciences, livestock production, and other fields.

  7. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This report is the fourth in a series of Annual Technical Summary Reports for the Advanced Turbine Technology Applications Project (ATTAP). This report covers plans and progress on ceramics development for commercial automotive applications over the period 1 Jan. - 31 Dec. 1991. Project effort conducted under this contract is part of the DOE Gas Turbine Highway Vehicle System program. This program is directed to provide the U.S. automotive industry the high-risk, long-range technology necessary to produce gas turbine engines for automobiles with reduced fuel consumption, reduced environmental impact, and a decreased reliance on scarce materials and resources. The program is oriented toward developing the high-risk technology of ceramic structural component design and fabrication, such that industry can carry this technology forward to production in the 1990s. The ATTAP test bed engine, carried over from the previous AGT101 project, is being used for verification testing of the durability of next-generation ceramic components, and their suitability for service at Reference Powertrain Design conditions. This document reports the technical effort conducted by GAPD and the ATTAP subcontractors during the fourth year of the project. Topics covered include ceramic processing definition and refinement, design improvements to the ATTAP test bed engine and test rigs and the methodology development of ceramic impact and fracture mechanisms. Appendices include reports by ATTAP subcontractors in the development of silicon nitride and silicon carbide families of materials and processes.

  8. Advanced Gas Turbine (AGT) technology development project

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This report is the final in a series of Technical Summary Reports for the Advanced Gas Turbine (AGT) Technology Development Project, authorizrd under NASA Contract DEN3-167 and sponsored by the DOE. The project was administered by NASA-Lewis Research Center of Cleveland, Ohio. Plans and progress are summarized for the period October 1979 through June 1987. This program aims to provide the US automotive industry the high risk, long range technology necessary to produce gas turbine engines for automobiles that will reduce fuel consumption and reduce environmental impact. The intent is that this technology will reach the marketplace by the 1990s. The Garrett/Ford automotive AGT was designated AGT101. The AGT101 is a 74.5 kW (100 shp) engine, capable of speeds to 100,000 rpm, and operates at turbine inlet temperatures to 1370 C (2500 F) with a specific fuel consumption level of 0.18 kg/kW-hr (0.3 lbs/hp-hr) over most of the operating range. This final report summarizes the powertrain design, power section development and component/ceramic technology development.

  9. Advanced Technologies for Design Information Verification

    SciTech Connect

    Watkins, Michael L.; Sheen, David M.; Rose, Joseph L.; Cumblidge, Stephen E.

    2009-07-08

    This paper discusses several technologies that have the potential to enhance facilities design verification. These approaches have shown promise in addressing the challenges associated with the verification of sub-component geometry and material composition for structures that are not directly accessible for physical inspection. A simple example is a pipe that extends into or through a wall or foundation. Both advanced electromagnetic and acoustic modalities will be discussed. These include advanced radar imaging, transient thermographic imaging, and guided acoustic wave imaging. Examples of current applications are provided. The basic principles and mechanisms of these inspection techniques are presented along with the salient practical features, advantages, and disadvantages of each technique. Other important considerations, such as component geometries, materials, and degree of access are also treated. The importance of, and strategies for, developing valid inspection models are also discussed. Beyond these basic technology adaptation and evaluation issues, important user interface considerations are outlined, along with approaches to quantify the overall performance reliability of the various inspection methods.

  10. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Reports technical effort by AlliedSignal Engines in sixth year of DOE/NASA funded project. Topics include: gas turbine engine design modifications of production APU to incorporate ceramic components; fabrication and processing of silicon nitride blades and nozzles; component and engine testing; and refinement and development of critical ceramics technologies, including: hot corrosion testing and environmental life predictive model; advanced NDE methods for internal flaws in ceramic components; and improved carbon pulverization modeling during impact. ATTAP project is oriented toward developing high-risk technology of ceramic structural component design and fabrication to carry forward to commercial production by 'bridging the gap' between structural ceramics in the laboratory and near-term commercial heat engine application. Current ATTAP project goal is to support accelerated commercialization of advanced, high-temperature engines for hybrid vehicles and other applications. Project objectives are to provide essential and substantial early field experience demonstrating ceramic component reliability and durability in modified, available, gas turbine engine applications; and to scale-up and improve manufacturing processes of ceramic turbine engine components and demonstrate application of these processes in the production environment.

  11. Coronary artery stents: advances in technology.

    PubMed

    Sheth, Sameer D; Giugliano, Robert P

    2014-10-01

    The introduction of percutaneous coronary intervention (PCI) in the late 1970s revolutionized the management of stable and unstable coronary artery disease, providing an effective, quick, safe, and increasingly widely available method for coronary revascularization for many patients. Rapid development in this field led to the introduction of a number of new technologies, including intracoronary stents that have resulted in improved efficacy and long-term safety. In this manuscript we review the experience with the 2 major available classes of stents (bare metal [BMS], drug-eluting [DES]) and describe the delivery systems for these stents. An evidence review of the large trial data comparing balloon angioplasty, BMS, and DES demonstrates the incremental advances over time, with the latest generation of DES achieving the lowest rates of restenosis, stent thrombosis, and recurrent myocardial infarction. In addition, we provide an overview of the latest developments in stent technology, including the introduction of bioresorbable stents and new stent delivery systems. These latest advances are hoped to further improve outcomes while reducing costs due to a reduction in the need for future procedures and hospitalizations due to recurrent coronary disease.

  12. Workshop on advanced technologies for planetary instruments

    NASA Technical Reports Server (NTRS)

    Appleby, J. (Editor)

    1993-01-01

    NASA's robotic solar system exploration program requires a new generation of science instruments. Design concepts are now judged against stringent mass, power, and size constraints--yet future instruments must be highly capable, reliable, and, in some applications, they must operate for many years. The most important single constraint, however, is cost: new instruments must be developed in a tightly controlled design-to-cost environment. Technical innovation is the key to success and will enable the sophisticated measurements needed for future scientific exploration. As a fundamental benefit, the incorporation of breakthrough technologies in planetary flight hardware will contribute to U.S. industrial competitiveness and will strengthen the U.S. technology base. The Workshop on Advanced Technologies for Planetary Instruments was conceived to address these challenges, to provide an open forum in which the NASA and DoD space communities could become better acquainted at the working level, and to assess future collaborative efforts. Over 300 space scientists and engineers participated in the two-and-a-half-day meeting held April 28-30, 1993, in Fairfax, Virginia. It was jointly sponsored by NASA's Solar System Exploration Division (SSED), within the Office of Space Science (OSS); NASA's Office of Advanced Concepts and Technology (OACT); DoD's Strategic Defense Initiative Organization (SDIO), now called the Ballistic Missile Defense Organization (BMDO); and the Lunar and Planetary Institute (LPI). The meeting included invited oral and contributed poster presentations, working group sessions in four sub-disciplines, and a wrap-up panel discussion. On the first day, the planetary science community described instrumentation needed for missions that may go into development during the next 5 to 10 years. Most of the second day was set aside for the DoD community to inform their counterparts in planetary science about their interests and capabilities, and to describe the

  13. Advanced Electric Traction System Technology Development

    SciTech Connect

    Anderson, Iver

    2011-01-14

    As a subcontractor to General Motors (GM), Ames Laboratory provided the technical expertise and supplied experimental materials needed to assess the technology of high energy bonded permanent magnets that are injection or compression molded for use in the Advanced Electric Traction System motor. This support was a sustained (Phase 1: 6/07 to 3/08) engineering effort that builds on the research achievements of the primary FreedomCAR project at Ames Laboratory on development of high temperature magnet alloy particulate in both flake and spherical powder forms. Ames Lab also provide guidance and direction in selection of magnet materials and supported the fabrication of experimental magnet materials for development of injection molding and magnetization processes by Arnold Magnetics, another project partner. The work with Arnold Magnetics involved a close collaboration on particulate material design and processing to achieve enhanced particulate properties and magnetic performance in the resulting bonded magnets. The overall project direction was provided by GM Program Management and two design reviews were held at GM-ATC in Torrance, CA. Ames Lab utilized current expertise in magnet powder alloy design and processing, along with on-going research advances being achieved under the existing FreedomCAR Program project to help guide and direct work during Phase 1 for the Advanced Electric Traction System Technology Development Program. The technical tasks included review of previous GM and Arnold Magnets work and identification of improvements to the benchmark magnet material, Magnequench MQP-14-12. Other benchmark characteristics of the desired magnet material include 64% volumetric loading with PPS polymer and a recommended maximum use temperature of 200C. A collaborative relationship was maintained with Arnold Magnets on the specification and processing of the bonded magnet material required by GM-ATC.

  14. Stem cell technology for neurodegenerative diseases.

    PubMed

    Lunn, J Simon; Sakowski, Stacey A; Hur, Junguk; Feldman, Eva L

    2011-09-01

    Over the past 20 years, stem cell technologies have become an increasingly attractive option to investigate and treat neurodegenerative diseases. In the current review, we discuss the process of extending basic stem cell research into translational therapies for patients suffering from neurodegenerative diseases. We begin with a discussion of the burden of these diseases on society, emphasizing the need for increased attention toward advancing stem cell therapies. We then explain the various types of stem cells utilized in neurodegenerative disease research, and outline important issues to consider in the transition of stem cell therapy from bench to bedside. Finally, we detail the current progress regarding the applications of stem cell therapies to specific neurodegenerative diseases, focusing on Parkinson disease, Huntington disease, Alzheimer disease, amyotrophic lateral sclerosis, and spinal muscular atrophy. With a greater understanding of the capacity of stem cell technologies, there is growing public hope that stem cell therapies will continue to progress into realistic and efficacious treatments for neurodegenerative diseases.

  15. Advanced energy systems and technologies - National R and D programme

    NASA Astrophysics Data System (ADS)

    Lund, P. D.

    1992-08-01

    The energy R and D in Finland is accomplished through the energy research programs of the Ministry of Trade and Industry. Today there are some 12 R and D programs in operation covering the various aspects of the energy sector. The NEMO-program deals with advanced new energy technologies and systems. The NEMO-program was launched in 1988 and it ends at the end of 1992. Helsinki University of Technology has been responsible for the coordination and most of the universities, research centers, and companies on new advanced energy technologies have been involved in the realization of NEMO. The objectives of the program have been to assess the potential of new technologies in the Finnish energy supply system, encourage and support businesses, and to create necessary research tradition in Finland. At the beginning in year 1988, several new technologies were included, but as the knowledge has increased, focusing on the most promising fields has taken place. Wind and solar energy show the best promises in respect to business activities and possibilities for utilization in Finland. Energy storage some other advanced technologies such as fuel cells and hydrogen technologies represented in the NEMO-program have an important role, but the commercial applications lie more distant in the future. The NEMO-program has reached its objectives. The international evaluation in fall 1990 gave very positive feedback and the scientific quality of the work was found good. At the same time, the contents was still focused more on commercial applications to support national industries in the field. The descriptions of the ongoing NEMO research projects are included in this report.

  16. Advances in space technology: the NSBRI Technology Development Team

    NASA Technical Reports Server (NTRS)

    Maurer, R. H.; Charles, H. K. Jr; Pisacane, V. L.

    2002-01-01

    As evidenced from Mir and other long-duration space missions, the space environment can cause significant alterations in the human physiology that could prove dangerous for astronauts. The NASA programme to develop countermeasures for these deleterious human health effects is being carried out by the National Space Biomedical Research Institute (NSBRI). The NSBRI has 12 research teams, ten of which are primarily physiology based, one addresses on-board medical care, and the twelfth focuses on technology development in support of the other research teams. This Technology Development (TD) Team initially supported four instrumentation developments: (1) an advanced, multiple projection, dual energy X ray absorptiometry (AMPDXA) scanning system: (2) a portable neutron spectrometer; (3) a miniature time-of-flight mass spectrometer: and (4) a cardiovascular identification system. Technical highlights of the original projects are presented along with an introduction to the five new TD Team projects being funded by the NSBRI.

  17. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-01-20

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/Biological Extraction; (4) Modeling and Control; and (5) Environmental Control.

  18. Regenerative medicine: advances in new methods and technologies.

    PubMed

    Park, Dong-Hyuk; Eve, David J

    2009-11-01

    The articles published in the journal Cell Transplantation - The Regenerative Medicine Journal over the last two years reveal the recent and future cutting-edge research in the fields of regenerative and transplantation medicine. 437 articles were published from 2007 to 2008, a 17% increase compared to the 373 articles in 2006-2007. Neuroscience was still the most common section in both the number of articles and the percentage of all manuscripts published. The increasing interest and rapid advance in bioengineering technology is highlighted by tissue engineering and bioartificial organs being ranked second again. For a similar reason, the methods and new technologies section increased significantly compared to the last period. Articles focusing on the transplantation of stem cell lineages encompassed almost 20% of all articles published. By contrast, the non-stem cell transplantation group which is made up primarily of islet cells, followed by biomaterials and fetal neural tissue, etc. comprised less than 15%. Transplantation of cells pre-treated with medicine or gene transfection to prolong graft survival or promote differentiation into the needed phenotype, was prevalent in the transplantation articles regardless of the kind of cells used. Meanwhile, the majority of non-transplantation-based articles were related to new devices for various purposes, characterization of unknown cells, medicines, cell preparation and/or optimization for transplantation (e.g. isolation and culture), and disease pathology.

  19. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher Hull

    2009-10-31

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium -- Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno - that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/biological extraction; (4) Modeling and control; and (5) Environmental control. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed by category, along with brief abstracts of their aims and objectives.

  20. Land reclamation: Advances in research technology

    SciTech Connect

    Younos, T.; Diplas, P.; Mostaghimi, S.

    1992-01-01

    Land reclamation encompasses remediation of industrial wasteland, improvement of infertile land for agricultural production, preservation of wetlands, and restoration of disturbed areas. Land reclamation is an integral part of sustainable development which aims to reconcile economic productivity with environmental preservation. During the 1980s, significant progress was achieved in the application of advanced technologies to sustainable development projects. The goal of this international symposium was to serve as a forum to review current research and state-of-the-art technology dealing with various aspects of land reclamation, and provide an opportunity for professional interaction and exchange of information in a multi-disciplinary setting. The scope of the symposium was as broad as the topic itself. The keynote address by Professor John Cairns focused on a systems approach in land restoration projects and challenges facing scientists in global biotic impoverishment. Other topics discussed in ten mechanical sessions included development and applications of computer models, geographic information systems, remote sensing technology, salinity problems, surface and ground water monitoring, reclamation of mine areas, soil amendment methods and impacts, wetland restoration techniques, and land use planning for resource protection.

  1. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Charles M. Boyer II; Ronald J. MacDonald P.G.

    2002-01-01

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger-Holditch Reservoir Technologies (H-RT) has joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners have provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project are to develop and validate methodologies that can quickly and cost-effectively identify wells with enhancement potential. We have continued to enhance and streamline our software, and we are testing the final stages of our new Microsoft{trademark} Access/Excel based software. We are continuing to process the information and are identifying potential candidate wells that can be used in Phase 2 to validate the new methodologies. In addition, preparation of the final technical report is underway. During this quarter, we have presented our project and discussed the software to numerous Petroleum Technology Transfer Council (PTTC) workshops located in various regions of the United States.

  2. NASA's Advanced Information Systems Technology (AIST) Program: Advanced Concepts and Disruptive Technologies

    NASA Astrophysics Data System (ADS)

    Little, M. M.; Moe, K.; Komar, G.

    2014-12-01

    NASA's Earth Science Technology Office (ESTO) manages a wide range of information technology projects under the Advanced Information Systems Technology (AIST) Program. The AIST Program aims to support all phases of NASA's Earth Science program with the goal of enabling new observations and information products, increasing the accessibility and use of Earth observations, and reducing the risk and cost of satellite and ground based information systems. Recent initiatives feature computational technologies to improve information extracted from data streams or model outputs and researchers' tools for Big Data analytics. Data-centric technologies enable research communities to facilitate collaboration and increase the speed with which results are produced and published. In the future NASA anticipates more small satellites (e.g., CubeSats), mobile drones and ground-based in-situ sensors will advance the state-of-the-art regarding how scientific observations are performed, given the flexibility, cost and deployment advantages of new operations technologies. This paper reviews the success of the program and the lessons learned. Infusion of these technologies is challenging and the paper discusses the obstacles and strategies to adoption by the earth science research and application efforts. It also describes alternative perspectives for the future program direction and for realizing the value in the steps to transform observations from sensors to data, to information, and to knowledge, namely: sensor measurement concepts development; data acquisition and management; data product generation; and data exploitation for science and applications.

  3. The Implementation of Advanced Solar Array Technology in Future NASA Missions

    NASA Technical Reports Server (NTRS)

    Piszczor, Michael F.; Kerslake, Thomas W.; Hoffman, David J.; White, Steve; Douglas, Mark; Spence, Brian; Jones, P. Alan

    2003-01-01

    Advanced solar array technology is expected to be critical in achieving the mission goals on many future NASA space flight programs. Current PV cell development programs offer significant potential and performance improvements. However, in order to achieve the performance improvements promised by these devices, new solar array structures must be designed and developed to accommodate these new PV cell technologies. This paper will address the use of advanced solar array technology in future NASA space missions and specifically look at how newer solar cell technologies impact solar array designs and overall power system performance.

  4. Advanced component technologies for energy-efficient turbofan engines

    NASA Technical Reports Server (NTRS)

    Saunders, N. T.

    1980-01-01

    A cooperative government-industry effort, the Energy Efficient Engine Project, to develop the advanced technology base for future commercial development of a new generation of more fuel conservative turbofan engines for airline use is described. Engine configurations that are dependent upon technology advances in each major engine component are defined and current design and development of the advanced components are included.

  5. Advanced Education and Technology Business Plan, 2010-13. Highlights

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2010

    2010-01-01

    The Ministry of Advanced Education and Technology envisions Alberta's prosperity through innovation and lifelong learning. Advanced Education and Technology's mission is to lead the development of a knowledge-driven future through a dynamic and integrated advanced learning and innovation system. This paper presents the highlights of the business…

  6. Advances in uncooled technology at BAE SYSTEMS

    NASA Astrophysics Data System (ADS)

    Backer, Brian S.; Kohin, Margaret; Leary, Arthur R.; Blackwell, Richard J.; Rumbaugh, Roy N.

    2003-09-01

    BAE SYSTEMS has made tremendous progress in uncooled technology and systems in the last year. In this paper we present performance results and imagery from our latest 640x480 and 320x240 small pixel focal plane arrays. Both were produced using submicron lithography and have achieved our lowest NETDs to date. Testing of the 320x240 devices has shown TNETDs of 30mK at F/1. Video imagery from our 640 x 480 uncooled camera installed in a POINTER Unattended Aerial Vehicle is also shown. In addition, we introduce our newest commercial imaging camera core, the SCC500 and show its vastly improved characteristics. Lastly, plans for future advancements are outlined.

  7. Next generation sequencing technology: Advances and applications.

    PubMed

    Buermans, H P J; den Dunnen, J T

    2014-10-01

    Impressive progress has been made in the field of Next Generation Sequencing (NGS). Through advancements in the fields of molecular biology and technical engineering, parallelization of the sequencing reaction has profoundly increased the total number of produced sequence reads per run. Current sequencing platforms allow for a previously unprecedented view into complex mixtures of RNA and DNA samples. NGS is currently evolving into a molecular microscope finding its way into virtually every fields of biomedical research. In this chapter we review the technical background of the different commercially available NGS platforms with respect to template generation and the sequencing reaction and take a small step towards what the upcoming NGS technologies will bring. We close with an overview of different implementations of NGS into biomedical research. This article is part of a Special Issue entitled: From Genome to Function.

  8. Advanced monolithic pixel sensors using SOI technology

    NASA Astrophysics Data System (ADS)

    Miyoshi, Toshinobu; Arai, Yasuo; Asano, Mari; Fujita, Yowichi; Hamasaki, Ryutaro; Hara, Kazuhiko; Honda, Shunsuke; Ikegami, Yoichi; Kurachi, Ikuo; Mitsui, Shingo; Nishimura, Ryutaro; Tauchi, Kazuya; Tobita, Naoshi; Tsuboyama, Toru; Yamada, Miho

    2016-07-01

    We are developing advanced pixel sensors using silicon-on-insulator (SOI) technology. A SOI wafer is used; top silicon is used for electric circuit and bottom silicon is used as a sensor. Target applications are high-energy physics, X-ray astronomy, material science, non-destructive inspection, medical application and so on. We have developed two integration-type pixel sensors, FPIXb and INTPIX7. These sensors were processed on single SOI wafers with various substrates in n- or p-type and double SOI wafers. The development status of double SOI sensors and some up-to-date test results of n-type and p-type SOI sensors are shown.

  9. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This report summarizes work performed in support of the development and demonstration of a structural ceramic technology for automotive gas turbine engines. The AGT101 regenerated gas turbine engine developed under the previous DOE/NASA Advanced Gas Turbine (AGT) program is being utilized for verification testing of the durability of next-generation ceramic components and their suitability for service at reference powertrain design conditions. Topics covered in this report include ceramic processing definition and refinement, design improvements to the test bed engine and test rigs, and design methodologies related to ceramic impact and fracture mechanisms. Appendices include reports by ATTAP subcontractors addressing the development of silicon nitride and silicon carbide families of materials and processes.

  10. Advanced information technology: Building stronger databases

    SciTech Connect

    Price, D.

    1994-12-01

    This paper discusses the attributes of the Advanced Information Technology (AIT) tool set, a database application builder designed at the Lawrence Livermore National Laboratory. AIT consists of a C library and several utilities that provide referential integrity across a database, interactive menu and field level help, and a code generator for building tightly controlled data entry support. AIT also provides for dynamic menu trees, report generation support, and creation of user groups. Composition of the library and utilities is discussed, along with relative strengths and weaknesses. In addition, an instantiation of the AIT tool set is presented using a specific application. Conclusions about the future and value of the tool set are then drawn based on the use of the tool set with that specific application.

  11. National Coalition of Advanced Technology Centers Proposal to the Nation.

    ERIC Educational Resources Information Center

    National Coalition of Advanced Technology Centers, Waco, TX.

    In 1988, nine institutions operating advanced technology centers (ATC's) to provide workers with up-to-date technical skills formed the National Coalition of Advanced Technology Centers (NCATC). The center was established to increase awareness of ATC's, serve as a forum for the discussion and demonstration of new and underused technologies,…

  12. NASA Lewis advanced IPV nickel-hydrogen technology

    NASA Technical Reports Server (NTRS)

    Smithrick, John J.; Britton, Doris L.

    1993-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts. Some of the advancements are as follows: to use 26 percent potassium hydroxide electrolyte to improve cycle life and performance, to modify the state of the art cell design to eliminate identified failure modes and further improve cycle life, and to develop a lightweight nickel electrode to reduce battery mass, hence reduce launch and/or increase satellite payload. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen battery cells was reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 accelerated LEO cycles at 80 percent DOD compared to 3,500 cycles for cells containing 31 percent KOH. Results of the boiler plate cell tests have been validated at NWSC, Crane, Indiana. Forty-eight ampere-hour flight cells containing 26 and 31 percent KOH have undergone real time LEO cycle life testing at an 80 percent DOD, 10 C. The three cells containing 26 percent KOH failed on the average at cycle 19,500. The three cells containing 31 percent KOH failed on the average at cycle 6,400. Validation testing of NASA Lewis 125 Ah advanced design IPV nickel-hydrogen flight cells is also being conducted at NWSC, Crane, Indiana under a NASA Lewis contract. This consists of characterization, storage, and cycle life testing. There was no capacity degradation after 52 days of storage with the cells in the discharged state, on open circuit, 0 C, and a hydrogen pressure of 14.5 psia. The catalyzed wall wick cells have been cycled for over 22,694 cycles with no cell failures in the continuing test. All three of the non-catalyzed wall wick cells failed (cycles 9,588; 13,900; and 20,575). Cycle life test results of the Fibrex nickel electrode has demonstrated the feasibility of an improved nickel electrode giving a higher specific energy nickel-hydrogen cell. A nickel-hydrogen boiler plate cell using an 80

  13. NASA Lewis advanced IPV nickel-hydrogen technology

    NASA Astrophysics Data System (ADS)

    Smithrick, John J.; Britton, Doris L.

    1993-11-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts. Some of the advancements are as follows: to use 26 percent potassium hydroxide electrolyte to improve cycle life and performance, to modify the state of the art cell design to eliminate identified failure modes and further improve cycle life, and to develop a lightweight nickel electrode to reduce battery mass, hence reduce launch and/or increase satellite payload. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen battery cells was reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 accelerated LEO cycles at 80 percent DOD compared to 3,500 cycles for cells containing 31 percent KOH. Results of the boiler plate cell tests have been validated at NWSC, Crane, Indiana. Forty-eight ampere-hour flight cells containing 26 and 31 percent KOH have undergone real time LEO cycle life testing at an 80 percent DOD, 10 C. The three cells containing 26 percent KOH failed on the average at cycle 19,500. The three cells containing 31 percent KOH failed on the average at cycle 6,400. Validation testing of NASA Lewis 125 Ah advanced design IPV nickel-hydrogen flight cells is also being conducted at NWSC, Crane, Indiana under a NASA Lewis contract. This consists of characterization, storage, and cycle life testing. There was no capacity degradation after 52 days of storage with the cells in the discharged state, on open circuit, 0 C, and a hydrogen pressure of 14.5 psia. The catalyzed wall wick cells have been cycled for over 22,694 cycles with no cell failures in the continuing test. All three of the non-catalyzed wall wick cells failed (cycles 9,588; 13,900; and 20,575). Cycle life test results of the Fibrex nickel electrode has demonstrated the feasibility of an improved nickel electrode giving a higher specific energy nickel-hydrogen cell. A nickel-hydrogen boiler plate cell using an 80

  14. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Advanced Turbine Technologies Application Project (ATTAP) is in the fifth year of a multiyear development program to bring the automotive gas turbine engine to a state at which industry can make commercialization decisions. Activities during the past year included reference powertrain design updates, test-bed engine design and development, ceramic component design, materials and component characterization, ceramic component process development and fabrication, ceramic component rig testing, and test-bed engine fabrication and testing. Engine design and development included mechanical design, combustion system development, alternate aerodynamic flow testing, and controls development. Design activities included development of the ceramic gasifier turbine static structure, the ceramic gasifier rotor, and the ceramic power turbine rotor. Material characterization efforts included the testing and evaluation of five candidate high temperature ceramic materials. Ceramic component process development and fabrication, with the objective of approaching automotive volumes and costs, continued for the gasifier turbine rotor, gasifier turbine scroll, extruded regenerator disks, and thermal insulation. Engine and rig fabrication, testing, and development supported improvements in ceramic component technology. Total test time in 1992 amounted to 599 hours, of which 147 hours were engine testing and 452 were hot rig testing.

  15. CCSDS - Advancing Spaceflight Technology for International Collaboration

    NASA Technical Reports Server (NTRS)

    Kearney, Mike; Kiely, Aaron; Yeh, Penshu; Gerner, Jean-Luc; Calzolari, Gian-Paolo; Gifford, Kevin; Merri, Mario; Weiss, Howard

    2010-01-01

    The Consultative Committee for Space Data Systems (CCSDS) has been developing data and communications standards since 1982, with the objective of providing interoperability for enabling international collaboration for spaceflight missions. As data and communications technology has advanced, CCSDS has progressed to capitalize on existing products when available and suitable for spaceflight, and to develop innovative new approaches when available products fail. The current scope of the CCSDS architecture spans the end-to-end data architecture of a spaceflight mission, with ongoing efforts to develop and standardize cutting-edge technology. This manuscript describes the overall architecture, the position of CCSDS in the standards and international mission community, and some CCSDS processes. It then highlights in detail several of the most interesting and critical technical areas in work right now, and how they support collaborative missions. Special topics include: Delay/Disruption Tolerant Networking (DTN), Asynchronous Message Service (AMS), Multispectral/Hyperspectral Data Compression (MHDC), Coding and Synchronization, Onboard Wireless, Spacecraft Monitor and Control, Navigation, Security, and Time Synchronization/Correlation. Broad international participation in development of CCSDS standards is encouraged.

  16. Advanced Technology Composite Fuselage - Materials and Processes

    NASA Technical Reports Server (NTRS)

    Scholz, D. B.; Dost, E. F.; Flynn, B. W.; Ilcewicz, L. B.; Nelson, K. M.; Sawicki, A. J.; Walker, T. H.; Lakes, R. S.

    1997-01-01

    The goal of Boeing's Advanced Technology Composite Aircraft Structures (ATCAS) program was to develop the technology required for cost and weight efficient use of composite materials in transport fuselage structure. This contractor report describes results of material and process selection, development, and characterization activities. Carbon fiber reinforced epoxy was chosen for fuselage skins and stiffening elements and for passenger and cargo floor structures. The automated fiber placement (AFP) process was selected for fabrication of monolithic and sandwich skin panels. Circumferential frames and window frames were braided and resin transfer molded (RTM'd). Pultrusion was selected for fabrication of floor beams and constant section stiffening elements. Drape forming was chosen for stringers and other stiffening elements. Significant development efforts were expended on the AFP, braiding, and RTM processes. Sandwich core materials and core edge close-out design concepts were evaluated. Autoclave cure processes were developed for stiffened skin and sandwich structures. The stiffness, strength, notch sensitivity, and bearing/bypass properties of fiber-placed skin materials and braided/RTM'd circumferential frame materials were characterized. The strength and durability of cocured and cobonded joints were evaluated. Impact damage resistance of stiffened skin and sandwich structures typical of fuselage panels was investigated. Fluid penetration and migration mechanisms for sandwich panels were studied.

  17. Advanced Technology Composite Fuselage-Structural Performance

    NASA Technical Reports Server (NTRS)

    Walker, T. H.; Minguet, P. J.; Flynn, B. W.; Carbery, D. J.; Swanson, G. D.; Ilcewicz, L. B.

    1997-01-01

    Boeing is studying the technologies associated with the application of composite materials to commercial transport fuselage structure under the NASA-sponsored contracts for Advanced Technology Composite Aircraft Structures (ATCAS) and Materials Development Omnibus Contract (MDOC). This report addresses the program activities related to structural performance of the selected concepts, including both the design development and subsequent detailed evaluation. Design criteria were developed to ensure compliance with regulatory requirements and typical company objectives. Accurate analysis methods were selected and/or developed where practical, and conservative approaches were used where significant approximations were necessary. Design sizing activities supported subsequent development by providing representative design configurations for structural evaluation and by identifying the critical performance issues. Significant program efforts were directed towards assessing structural performance predictive capability. The structural database collected to perform this assessment was intimately linked to the manufacturing scale-up activities to ensure inclusion of manufacturing-induced performance traits. Mechanical tests were conducted to support the development and critical evaluation of analysis methods addressing internal loads, stability, ultimate strength, attachment and splice strength, and damage tolerance. Unresolved aspects of these performance issues were identified as part of the assessments, providing direction for future development.

  18. Advanced Technology Composite Fuselage: Program Overview

    NASA Technical Reports Server (NTRS)

    Ilcewicz, L. B.; Smith, P. J.; Hanson, C. T.; Walker, T. H.; Metschan, S. L.; Mabson, G. E.; Wilden, K. S.; Flynn, B. W.; Scholz, D. B.; Polland, D. R.; Fredrikson, H. G.; Olson, J. T.; Backman, B. F.

    1997-01-01

    The Advanced Technology Composite Aircraft Structures (ATCAS) program has studied transport fuselage structure with a large potential reduction in the total direct operating costs for wide-body commercial transports. The baseline fuselage section was divided into four 'quadrants', crown, keel, and sides, gaining the manufacturing cost advantage possible with larger panels. Key processes found to have savings potential include (1) skins laminated by automatic fiber placement, (2) braided frames using resin transfer molding, and (3) panel bond technology that minimized mechanical fastening. The cost and weight of the baseline fuselage barrel was updated to complete Phase B of the program. An assessment of the former, which included labor, material, and tooling costs, was performed with the help of design cost models. Crown, keel, and side quadrant cost distributions illustrate the importance of panel design configuration, area, and other structural details. Composite sandwich panel designs were found to have the greatest cost savings potential for most quadrants. Key technical findings are summarized as an introduction to the other contractor reports documenting Phase A and B work completed in functional areas. The current program status in resolving critical technical issues is also highlighted.

  19. Advanced Life Support Technologies and Scenarios

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.

    2011-01-01

    As NASA looks beyond the International Space Station toward long-duration, deep space missions away from Earth, the current practice of supplying consumables and spares will not be practical nor affordable. New approaches are sought for life support and habitation systems that will reduce dependency on Earth and increase mission sustainability. To reduce launch mass, further closure of Environmental Control and Life Support Systems (ECLSS) beyond the current capability of the ISS will be required. Areas of particular interest include achieving higher degrees of recycling within Atmosphere Revitalization, Water Recovery and Waste Management Systems. NASA is currently investigating advanced carbon dioxide reduction processes that surpass the level of oxygen recovery available from the Sabatier Carbon Dioxide Reduction Assembly (CRA) on the ISS. Improving the efficiency of the recovery of water from spacecraft solid and liquid wastes is possible through use of emerging technologies such as the heat melt compactor and brine dewatering systems. Another significant consumable is that of food. Food production systems based on higher plants may not only contribute significantly to the diet, but also contribute to atmosphere revitalization, water purification and waste utilization. Bioreactors may be potentially utilized for wastewater and solid waste management. The level at which bioregenerative technologies are utilized will depend on their comparative requirements for spacecraft resources including mass, power, volume, heat rejection, crew time and reliability. Planetary protection requirements will need to be considered for missions to other solar system bodies.

  20. Advanced Technology for Isolating Payloads in Microgravity

    NASA Technical Reports Server (NTRS)

    Alhorn, Dean C.

    1997-01-01

    advances in isolation technology for that particular component. The final section presents some concluding thoughts and a summary of anticipated advances in research and development for isolating microgravity experiments.

  1. Technology Advancement of the Visible Nulling Coronagraph

    NASA Technical Reports Server (NTRS)

    Lyon, Richard G.; Clampin, Mark; Petrone, Peter; Thompson, Patrick; Bolcar, Matt; Madison, Timothy; Woodruff, Robert; Noecker, Charley; Kendrick, Steve

    2010-01-01

    The critical high contrast imaging technology for the Extrasolar Planetary Imaging Coronagraph (EPIC) mission concept is the visible nulling coronagraph (VNC). EPIC would be capable of imaging jovian planets, dust/debris disks, and potentially super-Earths and contribute to answering how bright the debris disks are for candidate stars. The contrast requirement for EPIC is 10(exp 9) contrast at 125 milli-arseconds inner working angle. To advance the VNC technology NASA/Goddard Space Flight Center, in collaboration with Lockheed-Martin, previously developed a vacuum VNC testbed, and achieved narrowband and broadband suppression of the core of the Airy disk. Recently our group was awarded a NASA Technology Development for Exoplanet Missions to achieve two milestones: (i) 10(exp 8) contrast in narrowband light, and, (ii) 10(ecp 9) contrast in broader band light; one milestone per year, and both at 2 Lambda/D inner working angle. These will be achieved with our 2nd generation testbed known as the visible nulling testbed (VNT). It contains a MEMS based hex-packed segmented deformable mirror known as the multiple mirror array (MMA) and coherent fiber bundle, i.e. a spatial filter array (SFA). The MMA is in one interferometric arm and works to set the wavefront differences between the arms to zero. Each of the MMA segments is optically mapped to a single mode fiber of the SFA, and the SFA passively cleans the sub-aperture wavefront error leaving only piston, tip and tilt error to be controlled. The piston degree of freedom on each segment is used to correct the wavefront errors, while the tip/tilt is used to simultaneously correct the amplitude errors. Thus the VNT controls both amplitude and wavefront errors with a single MMA in closed-loop in a vacuum tank at approx.20 Hz. Herein we will discuss our ongoing progress with the VNT.

  2. Morpheus: Advancing Technologies for Human Exploration

    NASA Technical Reports Server (NTRS)

    Olansen, Jon B.; Munday, Stephen R.; Mitchell, Jennifer D.; Baine, Michael

    2012-01-01

    NASA's Morpheus Project has developed and tested a prototype planetary lander capable of vertical takeoff and landing. Designed to serve as a vertical testbed (VTB) for advanced spacecraft technologies, the vehicle provides a platform for bringing technologies from the laboratory into an integrated flight system at relatively low cost. This allows individual technologies to mature into capabilities that can be incorporated into human exploration missions. The Morpheus vehicle is propelled by a LOX/Methane engine and sized to carry a payload of 1100 lb to the lunar surface. In addition to VTB vehicles, the Project s major elements include ground support systems and an operations facility. Initial testing will demonstrate technologies used to perform autonomous hazard avoidance and precision landing on a lunar or other planetary surface. The Morpheus vehicle successfully performed a set of integrated vehicle test flights including hot-fire and tethered hover tests, leading up to un-tethered free-flights. The initial phase of this development and testing campaign is being conducted on-site at the Johnson Space Center (JSC), with the first fully integrated vehicle firing its engine less than one year after project initiation. Designed, developed, manufactured and operated in-house by engineers at JSC, the Morpheus Project represents an unprecedented departure from recent NASA programs that traditionally require longer, more expensive development lifecycles and testing at remote, dedicated testing facilities. Morpheus testing includes three major types of integrated tests. A hot-fire (HF) is a static vehicle test of the LOX/Methane propulsion system. Tether tests (TT) have the vehicle suspended above the ground using a crane, which allows testing of the propulsion and integrated Guidance, Navigation, and Control (GN&C) in hovering flight without the risk of a vehicle departure or crash. Morpheus free-flights (FF) test the complete Morpheus system without the additional

  3. Advanced Wall Framing; BTS Technology Fact Sheet

    SciTech Connect

    Southface Energy Institute; Tromly, K.

    2000-11-07

    Advanced framing techniques for home construction have been researched extensively and proven effective. Both builders and home owners can benefit from advanced framing. Advanced framing techniques create a structurally sound home that has lower material and labor costs than a conventionally framed house. This fact sheet describes advanced framing techniques, design considerations, and framing.

  4. The ACTS Flight System - Cost-Effective Advanced Communications Technology. [Advanced Communication Technology Satellite

    NASA Technical Reports Server (NTRS)

    Holmes, W. M., Jr.; Beck, G. A.

    1984-01-01

    The multibeam communications package (MCP) for the Advanced Communications Technology Satellite (ACTS) to be STS-launched by NASA in 1988 for experimental demonstration of satellite-switched TDMA (at 220 Mbit/sec) and baseband-processor signal routing (at 110 or 27.5 Mbit/sec) is characterized. The developmental history of the ACTS, the program definition, and the spacecraft-bus and MCP parameters are reviewed and illustrated with drawings, block diagrams, and maps of the coverage plan. Advanced features of the MPC include 4.5-dB-noise-figure 30-GHz FET amplifiers and 20-GHz TWTA transmitters which provide either 40-W or 8-W RF output, depending on rain conditions. The technologies being tested in ACTS can give frequency-reuse factors as high as 20, thus greatly expanding the orbit/spectrum resources available for U.S. communications use.

  5. Benefits from synergies and advanced technologies for an advanced-technology space station

    NASA Technical Reports Server (NTRS)

    Garrett, L. Bernard; Ferebee, Melvin J., Jr.; Queijo, Manuel J.; Butterfield, Ansel J.

    1991-01-01

    A configuration for a second-generation advanced technology space station has been defined in a series of NASA-sponsored studies. Definitions of subsystems specifically addressed opportunities for beneficial synergistic interactions and those potential synergies and their benefits are identified. One of the more significant synergistic benefits involves the multi-function utilization of water within a large system that generates artificial gravity by rotation. In such a system, water not only provides the necessary crew life support, but also serves as counterrotator mass, as moveable ballast, and as a source for propellant gases. Additionally, the synergistic effects between advanced technology materials, operation at reduced artificial gravity, and lower cabin atmospheric pressure levels show beneficial interactions that can be quantified in terms of reduced mass to orbit.

  6. Advanced Thermal Control Technologies for "CEV" (New Name: ORION)

    NASA Technical Reports Server (NTRS)

    Golliher, Eric; Westheimer, David; Ewert, Michael; Hasan, Mojib; Anderson, Molly; Tuan, George; Beach, Duane

    2007-01-01

    NASA is currently investigating several technology options for advanced human spaceflight. This presentation covers some recent developments that relate to NASA's Orion spacecraft and future Lunar missions.

  7. Fish T cells: recent advances through genomics

    USGS Publications Warehouse

    Laing, Kerry J.; Hansen, John D.

    2011-01-01

    This brief review is intended to provide a concise overview of the current literature concerning T cells, advances in identifying distinct T cell functional subsets, and in distinguishing effector cells from memory cells. We compare and contrast a wealth of recent progress made in T cell immunology of teleost, elasmobranch, and agnathan fish, to knowledge derived from mammalian T cell studies. From genome studies, fish clearly have most components associated with T cell function and we can speculate on the presence of putative T cell subsets, and the ability to detect their differentiation to form memory cells. Some recombinant proteins for T cell associated cytokines and antibodies for T cell surface receptors have been generated that will facilitate studying the functional roles of teleost T cells during immune responses. Although there is still a long way to go, major advances have occurred in recent years for investigating T cell responses, thus phenotypic and functional characterization is on the near horizon.

  8. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    ATTAP activities during the past year were highlighted by an extensive materials assessment, execution of a reference powertrain design, test-bed engine design and development, ceramic component design, materials and component characterization, ceramic component process development and fabrication, component rig design and fabrication, test-bed engine fabrication, and hot gasifier rig and engine testing. Materials assessment activities entailed engine environment evaluation of domestically supplied radial gasifier turbine rotors that were available at the conclusion of the Advanced Gas Turbine (AGT) Technology Development Project as well as an extensive survey of both domestic and foreign ceramic suppliers and Government laboratories performing ceramic materials research applicable to advanced heat engines. A reference powertrain design was executed to reflect the selection of the AGT-5 as the ceramic component test-bed engine for the ATTAP. Test-bed engine development activity focused on upgrading the AGT-5 from a 1038 C (1900 F) metal engine to a durable 1371 C (2500 F) structural ceramic component test-bed engine. Ceramic component design activities included the combustor, gasifier turbine static structure, and gasifier turbine rotor. The materials and component characterization efforts have included the testing and evaluation of several candidate ceramic materials and components being developed for use in the ATTAP. Ceramic component process development and fabrication activities were initiated for the gasifier turbine rotor, gasifier turbine vanes, gasifier turbine scroll, extruded regenerator disks, and thermal insulation. Component rig development activities included combustor, hot gasifier, and regenerator rigs. Test-bed engine fabrication activities consisted of the fabrication of an all-new AGT-5 durability test-bed engine and support of all engine test activities through instrumentation/build/repair. Hot gasifier rig and test-bed engine testing

  9. Hydrogen-bromine fuel cell advance component development

    NASA Technical Reports Server (NTRS)

    Charleston, Joann; Reed, James

    1988-01-01

    Advanced cell component development is performed by NASA Lewis to achieve improved performance and longer life for the hydrogen-bromine fuel cells system. The state-of-the-art hydrogen-bromine system utilizes the solid polymer electrolyte (SPE) technology, similar to the SPE technology developed for the hydrogen-oxygen fuel cell system. These studies are directed at exploring the potential for this system by assessing and evaluating various types of materials for cell parts and electrode materials for Bromine-hydrogen bromine environment and fabricating experimental membrane/electrode-catalysts by chemical deposition.

  10. ADVANCED OXIDATION TECHNOLOGIES FOR THE TREATMENT OF CONTAMINATED GROUNDWATER

    EPA Science Inventory

    This paper presents information on two pilot-field appliations of advanced oxidation technologies for contaminated groundwater with organis. The two UV/oxidation technologies were developed by Ultrox International of Santa Ana, California and Peroxidatrion Systems, Inc. of Tucso...

  11. Advanced Cooling Technology, Inc. final technical progress report

    SciTech Connect

    Myers, H.S.

    1993-08-12

    Tasks performed to develop an improved version of Advanced Cooling Technology`s Evaporative Subcooling System are described. Work on pump stability, improved drainage mechanism, and the American Refrigeration Institute engineering performance tests is presented.

  12. Technological advances in the hemostasis laboratory.

    PubMed

    Lippi, Giuseppe; Plebani, Mario; Favaloro, Emmanuel J

    2014-03-01

    Automation is conventionally defined as the use of machines, control systems, and information technologies to optimize productivity. Although automation is now commonplace in several areas of diagnostic testing, especially in clinical chemistry and immunochemistry, the concept of extending this process to hemostasis testing has only recently been advanced. The leading drawbacks are still represented by the almost unique biological matrix because citrated plasma can only be used for clotting assays and few other notable exceptions, and by the highly specific pretreatment of samples, which is particularly distinct to other test systems. Despite these important limitations, a certain degree of automation is also now embracing hemostasis testing. The more relevant developments include the growing integration of routine hemostasis analyzers with track line systems and workcells, the development of specific instrumentation tools to enhance reliability of testing (i.e., signal detection with different technologies to increase test panels, plasma indices for preanalytical check of interfering substances, failure patterns sensors for identifying insufficient volume, clots or bubbles, cap-piercing for enhancing operator safety, automatic reflex testing, automatic redilution of samples, and laser barcode readers), preanalytical features (e.g., positive identification, automatic systems for tube(s) labeling, transillumination devices), and postphlebotomy tools (pneumatic tube systems for reducing turnaround time, sample transport boxes for ensuring stability of specimens, monitoring systems for identifying unsuitable conditions of transport). Regardless of these important innovations, coagulation/hemostasis testing still requires specific technical and clinical expertise, not only in terms of measurement procedures but also for interpreting and then appropriately utilizing the derived information. Thus, additional and special caution has to be used when designing projects of

  13. Physics and Advanced Technologies 2003 Annual Report

    SciTech Connect

    Hazi, A; Sketchley, J

    2005-01-20

    The Physics and Advanced Technologies (PAT) Directorate overcame significant challenges in 2003 to deliver a wealth of scientific and programmatic milestones, and move toward closer alignment with programs at Lawrence Livermore National Laboratory. We acted aggressively in enabling the PAT Directorate to contribute to future, growing Lawrence Livermore missions in homeland security and at the National Ignition Facility (NIF). We made heavy investments to bring new capabilities to the Laboratory, to initiate collaborations with major Laboratory programs, and to align with future Laboratory directions. Consistent with our mission, we sought to ensure that Livermore programs have access to the best science and technology, today and tomorrow. For example, in a move aimed at revitalizing the Laboratory's expertise in nuclear and radiation detection, we brought the talented Measurement Sciences Group to Livermore from Lawrence Berkeley National Laboratory, after its mission there had diminished. The transfer to our I Division entailed significant investment by PAT in equipment and infrastructure required by the group. In addition, the move occurred at a time when homeland security funding was expected, but not yet available. By the end of the year, though, the group was making crucial contributions to the radiation detection program at Livermore, and nearly every member was fully engaged in programmatic activities. Our V Division made a move of a different sort, relocating en masse from Building 121 to the NIF complex. This move was designed to enhance interaction and collaboration among high-energy-density experimental scientists at the Laboratory, a goal that is essential to the effective use of NIF in the future. Since then, V Division has become increasingly integrated with NIF activities. Division scientists are heavily involved in diagnostic development and fielding and are poised to perform equation-of-state and high-temperature hohlraum experiments in 2004 as

  14. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Advanced Turbine Technology Application Project (ATTAP) activities during the past year were highlighted by test-bed engine design and development activities; ceramic component design; materials and component characterization; ceramic component process development and fabrication; component rig testing; and test-bed engine fabrication and testing. Although substantial technical challenges remain, all areas exhibited progress. Test-bed engine design and development activity included engine mechanical design, power turbine flow-path design and mechanical layout, and engine system integration aimed at upgrading the AGT-5 from a 1038 C metal engine to a durable 1371 C structural ceramic component test-bed engine. ATTAP-defined ceramic and associated ceramic/metal component design activities include: the ceramic combustor body, the ceramic gasifier turbine static structure, the ceramic gasifier turbine rotor, the ceramic/metal power turbine static structure, and the ceramic power turbine rotors. The materials and component characterization efforts included the testing and evaluation of several candidate ceramic materials and components being developed for use in the ATTAP. Ceramic component process development and fabrication activities are being conducted for the gasifier turbine rotor, gasifier turbine vanes, gasifier turbine scroll, extruded regenerator disks, and thermal insulation. Component rig testing activities include the development of the necessary test procedures and conduction of rig testing of the ceramic components and assemblies. Four-hundred hours of hot gasifier rig test time were accumulated with turbine inlet temperatures exceeding 1204 C at 100 percent design gasifier speed. A total of 348.6 test hours were achieved on a single ceramic rotor without failure and a second ceramic rotor was retired in engine-ready condition at 364.9 test hours. Test-bed engine fabrication, testing, and development supported improvements in ceramic component technology

  15. Advanced technologies for encryption of satellite links

    NASA Astrophysics Data System (ADS)

    McMahan, Sherry S.

    The use of encryption on satellite links is discussed. Advanced technology exists to provide transmission security for large earth station with data rates up to 50 megabits per second. One of the major concerns in the use of encryption equipment with very small aperture terminals (VSAT) is the key management issue and the related operational costs. The low cost requirement and the lack of physical protection of remote VSATs place severe constraints on the design of encryption equipment. Encryption may be accomplished by embedding a tamper proof encryption module into the baseband unit of each VSAT. VSAT networks are usually star networks where there is a single large earth station that serves as a hub and all satellite communications takes place between each VSAT and the hub earth station. The hub earth station has the secret master key of each VSAT. These master keys are used to downline load encrypted session keys to each VSAT. A more secure alternative is to use public key techniques where each embedded VSAT encryption module internally generates its own secret and public numbers. The secret number never leaves the module while the public number is sent to the hub at the time of initialization of the encryption module into the VSAT. Physical access control to encryption modules of VSAT systems can be implemented using passwords, smart cards or biometrics.

  16. The technology behind Colgate Total Advanced Fresh.

    PubMed

    Williams, Malcolm I; Cummins, Diane

    2003-09-01

    In the early 1990s, a breakthrough toothpaste, Colgate Total, was launched with documented long-lasting activity against plaque, gingivitis, calculus, tooth decay, and bad breath. The technology behind this toothpaste is the combination of triclosan, a polyvinylmethylether/maleic acid copolymer, and sodium fluoride. The copolymer ensures maximal oral retention and subsequent release of the antibacterial triclosan. Effective levels of triclosan have been observed in the oral cavity 12 hours after brushing the teeth, allowing prolonged control of oral bacteria that may cause the most common dental problems, including bad breath. Similarly, the enhanced retention of triclosan to oral surfaces after using this revolutionary toothpaste for up to 2 years has led to significantly reduced incremental coronal caries compared to an American Dental Association-Approved anticavity fluoride toothpaste. Furthermore, significantly less calcium remained in dental plaque after brushing the teeth with the triclosan/copolymer toothpaste, resulting in the formation of less tartar. In keeping with the multiple oral health benefits provided by Colgate Total, consumers are now offered a new dentifrice, Colgate Total Advanced Fresh, which provides the numerous therapeutic and esthetic benefits that are the hallmark of Colgate Total. The new dentifrice, which contains an impactful breath-freshening flavor, has been documented to provide sustained control of bad breath over 12 hours.

  17. Advanced Lost Foam Casting Technology - Phase V

    SciTech Connect

    Wanliang Sun; Harry E. Littleton; Charles E. Bates

    2004-04-29

    Previous research, conducted under DOE Contracts DE-FC07-89ID12869, DE-FC07-93ID12230 and DE-FC07-95ID113358 made significant advances in understanding the Lost Foam Casting (LFC) Process and clearly identified areas where additional developments were needed to improve the process and make it more functional in industrial environments. The current project focused on eight tasks listed as follows: Task 1--Computational Model for the Process and Data Base to Support the Model; Task 2--Casting Dimensional Accuracy; Task 3--Pattern Production; Task 4--Improved Pattern Materials; Task 5--Coating Control; Task 6--In-Plant Case Studies; Task 7--Energy and the Environmental Data; and Task 8--Technology Transfer. This report summarizes the work done on all tasks in the period of October 1, 1999 through September 30, 2004. The results obtained in each task and subtask are summarized in this Executive Summary and details are provided in subsequent sections of the report.

  18. Advanced ignition and propulsion technology program

    SciTech Connect

    Oldenborg, R.; Early, J.; Lester, C.

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). Reliable engine re-ignition plays a crucial role in enabling commercial and military aircraft to fly safely at high altitudes. This project addressed research elements critical to the optimization of laser-based igniter. The effort initially involved a collaborative research and development agreement with B.F. Goodrich Aerospace and Laser Fare, Inc. The work involved integrated experiments with theoretical modeling to provide a basic understanding of the chemistry and physics controlling the laser-induced ignition of fuel aerosols produced by turbojet engine injectors. In addition, the authors defined advanced laser igniter configurations that minimize laser packaging size, weight, complexity and power consumption. These innovative ignition concepts were shown to reliably ignite jet fuel aerosols over a broad range of fuel/air mixture and a t fuel temperatures as low as -40 deg F. The demonstrated fuel ignition performance was highly superior to that obtained by the state-of-the-art, laser-spark ignition method utilizing comparable laser energy. The authors also developed a laser-based method that effectively removes optically opaque deposits of fuel hydrocarbon combustion residues from laser window surfaces. Seven patents have been either issued or are pending that resulted from the technology developments within this project.

  19. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Ronald J. MacDonald

    2005-04-27

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger Data & Consulting Services (DCS) joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners previously provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project were to develop and validate methodologies that can quickly and cost-effectively identify underperforming wells with remediation potential. We enhanced and streamlined our software and are using it with Microsoft's{trademark} Access and Excel programs. During the last quarter of 2002, Great Lakes provided us with additional data for approximately 2,200 wells located in their Cooperstown field situated in northwestern Pennsylvania. We identified approximately 220 potential remediation candidates and Great Lakes personnel reviewed this list for viability and selected more than twenty five wells to be reworked. Approximately fifteen wells have been successfully reworked as of year-end 2004. This field provided a rigorous test of our software and analytical methods. We processed all the information provided to us including the Cooperstown data. Great Lakes also provided supplemental data listing the original operator of the wells.

  20. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Ronald J. MacDonald

    2004-07-14

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger Data & Consulting Services (DCS) joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners previously provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project are to develop and validate methodologies that can quickly and cost-effectively identify underperforming wells with remediation potential. We have enhanced and streamlined our software and are using it with the latest versions of Microsoft's{trademark} Access and Excel programs. During the last quarter of 2002, Great Lakes provided us with additional data for approximately 2,200 wells located in their Cooperstown field situated in northwestern Pennsylvania. We identified approximately 130 potential remediation candidates, and Great Lakes personnel are currently reviewing this list for viable remediation. Within the last few weeks, a list of five candidates have been chosen for refract, in addition to two alternate wells. This field has provided a rigorous test of our software and analytical methods. We have processed all the information provided to us including the Cooperstown data. Great Lakes also provided supplemental data listing the original operator of the wells. We have determined whether a statistically significant number of underperformers correlate to specific operators and/or their associated completion/stimulation methods. In addition, the DOE has reviewed a draft version of a final report.

  1. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Ronald J. MacDonald

    2003-04-01

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger Data & Consulting Services (DCS) joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners previously provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project are to develop and validate methodologies that can quickly and cost-effectively identify wells with enhancement potential. We have enhanced and streamlined our software, and we are using the final version of our new Microsoft{trademark} Access/Excel programs. During the last quarter of 2002, we received additional data for approximately 2,200 wells from Great Lakes. This information pertains to their Cooperstown field located in northwestern Pennsylvania. We recognized approximately 130 potential remediation candidates, and Great Lakes' personnel are currently reviewing this list for viable remediation. This field has provided a rigorous test of our software and analytical methods. We have processed all the information provided to us including the Cooperstown data. Great Lakes also provided supplemental data listing the original operator of the wells. We are also determining whether a statistically significant number of underperformers correlate to specific operators and/or their associated completion/stimulation methods. In addition, the DOE has reviewed a draft version of a final report.

  2. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Ronald J. MacDonald

    2003-04-04

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger Data & Consulting Services (DCS) joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners previously provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project are to develop and validate methodologies that can quickly and cost-effectively identify wells with enhancement potential. We have enhanced and streamlined our software, and we are using the final version of our new Microsoft{trademark} Access/Excel programs. During the last quarter of 2002, we received additional data for approximately 2,200 wells from Great Lakes. This information pertains to their Cooperstown field located in northwestern Pennsylvania. We recognized approximately 130 potential remediation candidates, and Great Lakes' personnel are currently reviewing this list for viable remediation. This field has provided a rigorous test of our software and analytical methods. We have processed all the information provided to us including the Cooperstown data. Great Lakes also provided supplemental data listing the original operator of the wells. We have determined whether a statistically significant number of underperformers correlate to specific operators and/or their associated completion/stimulation methods. In addition, the DOE has reviewed a draft version of a final report.

  3. ADVANCED TECHNOLOGIES FOR STRIPPER GAS WELL ENHANCEMENT

    SciTech Connect

    Ronald J. MacDonald

    2003-01-01

    As part of Task 1 in Advanced Technologies for Stripper Gas Well Enhancement, Schlumberger Data & Consulting Services (DCS) joined with two Appalachian Basin producers, Great Lakes Energy Partners, LLC, and Belden & Blake Corporation to develop methodologies for identification and enhancement of stripper wells with economic upside potential. These industry partners previously provided us with data for more than 700 wells in northwestern Pennsylvania. Phase 1 goals of this project are to develop and validate methodologies that can quickly and cost-effectively identify wells with enhancement potential. We have enhanced and streamlined our software, and we are using the final version of our new Microsoft{trademark} Access/Excel based software. We have received additional data from Great Lakes pertaining to a Cooperstown field that is expected to have numerous remediation candidates. This field will provide a rigorous test of out software and analytical methods. We have processed all the information provided to us before receiving the Cooperstown data and are currently analyzing the new data. Great Lakes will be providing supplemental data in the near future that will identify the original operator of the wells. This will prove valuable in determining whether a statistically significant number of underperformers are a result of specific operators and their associated completion/stimulation methods. We have identified potential candidate wells for Phase 2 to validate the new methodologies. In addition, a draft version of a final report has been reviewed by DOE.

  4. The Advanced Communication Technology Satellite and ISDN

    NASA Technical Reports Server (NTRS)

    Lowry, Peter A.

    1996-01-01

    This paper depicts the Advanced Communication Technology Satellite (ACTS) system as a global central office switch. The ground portion of the system is the collection of earth stations or T1-VSAT's (T1 very small aperture terminals). The control software for the T1-VSAT's resides in a single CPU. The software consists of two modules, the modem manager and the call manager. The modem manager (MM) controls the RF modem portion of the T1-VSAT. It processes the orderwires from the satellite or from signaling generated by the call manager (CM). The CM controls the Recom Laboratories MSPs by receiving signaling messages from the stacked MSP shelves ro units and sending appropriate setup commands to them. There are two methods used to setup and process calls in the CM; first by dialing up a circuit using a standard telephone handset or, secondly by using an external processor connected to the CPU's second COM port, by sending and receiving signaling orderwires. It is the use of the external processor which permits the ISDN (Integrated Services Digital Network) Signaling Processor to implement ISDN calls. In August 1993, the initial testing of the ISDN Signaling Processor was carried out at ACTS System Test at Lockheed Marietta, Princeton, NJ using the spacecraft in its test configuration on the ground.

  5. Advanced Gas Turbine (AGT) Technology Development Project

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This report is the eleventh in the series of Technical Summary reports for the Advanced Gas Turbine (AGT) Technology Development Project, authorized under NASA Contract DEN3-167, and sponsored by the Department of Energy (DOE). This report was prepared by Garrett Turbine Engine Company, A Division of the Garrett Corporation, and includes information provided by Ford Motor Company, the Standard Oil Company, and AiResearch Casting Company. This report covers plans and progress for the period July 1, 1985 through June 30, 1986. Technical progress during the reported period was highlighted by the 85-hour endurance run of an all-ceramic engine operating in the 2000 to 2250 F temperature regime. Component development continued in the areas of the combustion/fuel injection system, regenerator and seals system, and ceramic turbine rotor attachment design. Component rig testing saw further refinements. Ceramic materials showed continued improvements in required properties for gas turbine applications; however, continued development is needed before performance and reliability goals can be set.

  6. Energy 101: Fuel Cell Technology

    ScienceCinema

    None

    2016-07-12

    Learn how fuel cell technology generates clean electricity from hydrogen to power our buildings and transportation-while emitting nothing but water. This video illustrates the fundamentals of fuel cell technology and its potential to supply our homes, offices, industries, and vehicles with sustainable, reliable energy.

  7. Energy 101: Fuel Cell Technology

    SciTech Connect

    2014-03-11

    Learn how fuel cell technology generates clean electricity from hydrogen to power our buildings and transportation-while emitting nothing but water. This video illustrates the fundamentals of fuel cell technology and its potential to supply our homes, offices, industries, and vehicles with sustainable, reliable energy.

  8. Advanced Technology Lifecycle Analysis System (ATLAS)

    NASA Technical Reports Server (NTRS)

    O'Neil, Daniel A.; Mankins, John C.

    2004-01-01

    Developing credible mass and cost estimates for space exploration and development architectures require multidisciplinary analysis based on physics calculations, and parametric estimates derived from historical systems. Within the National Aeronautics and Space Administration (NASA), concurrent engineering environment (CEE) activities integrate discipline oriented analysis tools through a computer network and accumulate the results of a multidisciplinary analysis team via a centralized database or spreadsheet Each minute of a design and analysis study within a concurrent engineering environment is expensive due the size of the team and supporting equipment The Advanced Technology Lifecycle Analysis System (ATLAS) reduces the cost of architecture analysis by capturing the knowledge of discipline experts into system oriented spreadsheet models. A framework with a user interface presents a library of system models to an architecture analyst. The analyst selects models of launchers, in-space transportation systems, and excursion vehicles, as well as space and surface infrastructure such as propellant depots, habitats, and solar power satellites. After assembling the architecture from the selected models, the analyst can create a campaign comprised of missions spanning several years. The ATLAS controller passes analyst specified parameters to the models and data among the models. An integrator workbook calls a history based parametric analysis cost model to determine the costs. Also, the integrator estimates the flight rates, launched masses, and architecture benefits over the years of the campaign. An accumulator workbook presents the analytical results in a series of bar graphs. In no way does ATLAS compete with a CEE; instead, ATLAS complements a CEE by ensuring that the time of the experts is well spent Using ATLAS, an architecture analyst can perform technology sensitivity analysis, study many scenarios, and see the impact of design decisions. When the analyst is

  9. Recent advances in NiMH battery technology

    NASA Astrophysics Data System (ADS)

    Fetcenko, M. A.; Ovshinsky, S. R.; Reichman, B.; Young, K.; Fierro, C.; Koch, J.; Zallen, A.; Mays, W.; Ouchi, T.

    Nickel-metal hydride (NiMH) is a commercially important rechargeable battery technology for both consumer and industrial applications due to design flexibility, excellent energy and power, environmental acceptability and cost. [1] From the initial product introduction in 1991 of cylindrical cells having an energy of 54 Wh kg -1, today's small consumer cells have a specific energy over 100 Wh kg -1. Numerous licensed manufacturers produce a myriad of NiMH products ranging from 30 mAh button cells to a wide variety of consumer cylindrical products, prismatic cells up to 250 Ah for electric buses and 6 Ah multicell modules for hybrid electric vehicles. Power has increased from under 200 to 1200 W kg -1 commercially and up to 2000 W kg -1 at a development level [2]. Early NiMH batteries had limited operating temperatures while today's batteries can provide excellent power at cold temperatures of -30 °C and provide over 90% capacity at 70 °C. Many of these product performance advances are a result of innovations to the metal hydride and nickel hydroxide materials. We will report on some of these key material advances which provide today's NiMH performance and new materials to allow higher energy, power and significant cost reduction.

  10. Advances in lightweight nickel electrode technology

    NASA Technical Reports Server (NTRS)

    Coates, Dwaine; Paul, Gary; Daugherty, Paul

    1989-01-01

    Studies are currently underway to further the development of lightweight nickel electrode technology. Work is focused primarily on the space nickel-hydrogen system and nickel-iron system but is also applicable to the nickel-cadmium and nickel-zinc systems. The goal is to reduce electrode weight while maintaining or improving performance, thereby increasing electrode energy density. Two basic electrode structures are being investigated. The first is the traditional nickel sponge produced from sintered nickel-carbonyl powder. The second is a new material for this application which consists of a non-woven mat of nickel fiber. Electrodes are being manufactured, tested, and evaluated at the electrode and cell level.

  11. Advances in lightweight nickel electrode technology

    NASA Technical Reports Server (NTRS)

    Coates, Dwaine; Paul, Gary; Wheeler, James R.; Daugherty, Paul

    1989-01-01

    Studies are currently underway to further the development of lightweight nickel electrode technology. Work is focused primarily on the space nickel-hydrogen system and nickel-iron system but is also applicable to the nickel-cadmium and nickel-zinc systems. The goal is to reduce electrode weight while maintaining or improving performance thereby increasing electrode energy density. Two basic electrode structures are being investigated. The first is the traditional nickel sponge produced from sintered nickel-carbonyl powder and the second is a new material for this application which consists of a non-woven mat of nickel fiber. Electrodes are being manufactured, tested and evaluated at the electrode and cell level.

  12. USAF advanced terrestrial energy study. Volume 2: Technology handbook

    NASA Astrophysics Data System (ADS)

    Daniels, E. J.; Yudow, B. D.; Donakowski, T. D.

    1983-04-01

    This report presents the results of the USAF Advanced Terrestrial Energy Study. The objective of that study was to develop a data base of key parameters of selected energy conversion and energy storage technologies. The data base includes present and expected (through 2000) performance goals of the systems. The data base was established through an extensive literature search, surveys of manufacturers and researchers, and statistical and qualitative analyses of the available input data. The results of the study are reported in four documents: (1) Project Summary; (2) Technology Handbook; (3) Parameter Survey; (4) Analysis, Data, Bibliography. Contents (Volume II): Diesels, Gas Turbines, Stirlings, Organic Rankine Cycle, Fuel Cells, Photovoltaic Energy Conversion System, Wind Turbines, Batteries, Thermal Energy Storage System.

  13. Glaucoma Diagnosis and Monitoring Using Advanced Imaging Technologies

    PubMed Central

    Sehi, Mitra; Iverson, Shawn M

    2014-01-01

    Advanced ocular imaging technologies facilitate objective and reproducible quantification of change in glaucoma but at the same time, impose new challenges on scientists and clinicians for separating true structural change from imaging noise. This review examines time-domain and spectral-domain optical coherence tomography, confocal scanning laser ophthalmoscopy and scanning laser polarimetry technologies and discusses the diagnostic accuracy and the ability of each technique for evaluation of glaucomatous progression. A broad review of the current literature reveals that objective assessment of retinal nerve fiber layer, ganglion cell complex and optic nerve head topography may improve glaucoma monitoring when used as a complementary tool in conjunction with the clinical judgment of an expert. PMID:24470807

  14. Stem and progenitor cells: advancing bone tissue engineering.

    PubMed

    Tevlin, R; Walmsley, G G; Marecic, O; Hu, Michael S; Wan, D C; Longaker, M T

    2016-04-01

    Unlike many other postnatal tissues, bone can regenerate and repair itself; nevertheless, this capacity can be overcome. Traditionally, surgical reconstructive strategies have implemented autologous, allogeneic, and prosthetic materials. Autologous bone--the best option--is limited in supply and also mandates an additional surgical procedure. In regenerative tissue engineering, there are myriad issues to consider in the creation of a functional, implantable replacement tissue. Importantly, there must exist an easily accessible, abundant cell source with the capacity to express the phenotype of the desired tissue, and a biocompatible scaffold to deliver the cells to the damaged region. A literature review was performed using PubMed; peer-reviewed publications were screened for relevance in order to identify key advances in stem and progenitor cell contribution to the field of bone tissue engineering. In this review, we briefly introduce various adult stem cells implemented in bone tissue engineering such as mesenchymal stem cells (including bone marrow- and adipose-derived stem cells), endothelial progenitor cells, and induced pluripotent stem cells. We then discuss numerous advances associated with their application and subsequently focus on technological advances in the field, before addressing key regenerative strategies currently used in clinical practice. Stem and progenitor cell implementation in bone tissue engineering strategies have the ability to make a major impact on regenerative medicine and reduce patient morbidity. As the field of regenerative medicine endeavors to harness the body's own cells for treatment, scientific innovation has led to great advances in stem cell-based therapies in the past decade.

  15. Advanced Education and Technology Business Plan, 2009-12

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2009

    2009-01-01

    The Ministry of Advanced Education and Technology consists of the following entities for budget purposes: Department of Advanced Education and Technology, the Access to the Future Fund, Alberta Enterprise Corporation, Alberta Research Council Inc., and iCORE Inc. Achieving the Ministry's goals involves the work and coordination of many…

  16. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    SciTech Connect

    Secretary Chu

    2009-07-16

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nation’s dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  17. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    ScienceCinema

    Secretary Chu

    2016-07-12

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nation’s dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  18. Advanced Technological Education Program: 1995 Awards and Activities.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC. Directorate for Education and Human Resources.

    The Advanced Technological Education (ATE) program promotes exemplary improvement in advanced technological education at the national and regional level through support of curriculum development and program improvement at the undergraduate and secondary school levels, especially for technicians being educated for the high performance workplace of…

  19. Advanced Education and Technology Business Plan, 2008-11

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2008

    2008-01-01

    The Ministry of Advanced Education and Technology's 2008-11 business plan identifies how it plans to work over the next three years to enhance advanced learning opportunities and innovation for all Albertans. Alberta's advanced learning system is composed of public board-governed institutions, the apprenticeship and industry training system,…

  20. Advanced technologies impact on compressor design and development: A perspective

    NASA Technical Reports Server (NTRS)

    Ball, Calvin L.

    1989-01-01

    A historical perspective of the impact of advanced technologies on compression system design and development for aircraft gas turbine applications is presented. A bright view of the future is projected in which further advancements in compression system technologies will be made. These advancements will have a significant impact on the ability to meet the ever-more-demanding requirements being imposed on the propulsion system for advanced aircraft. Examples are presented of advanced compression system concepts now being studied. The status and potential impact of transitioning from an empirically derived design system to a computationally oriented system are highlighted. A current NASA Lewis Research Center program to enhance this transitioning is described.

  1. Advanced technology's impact on compressor design and development - A perspective

    NASA Technical Reports Server (NTRS)

    Ball, Calvin L.

    1989-01-01

    A historical perspective of the impact of advanced technologies on compression system design and development for aircraft gas turbine applications is presented. A bright view of the future is projected in which further advancements in compression system technologies will be made. These advancements will have a significant impact on the ability to meet the ever-more-demanding requirements being imposed on the propulsion system for advanced aircraft. Examples are presented of advanced compression system concepts now being studied. The status and potential impact of transitioning from an empirically derived design system to a computationally oriented system are highlighted. A current NASA Lewis Research Center program to enhance this transitioning is described.

  2. Advanced drug delivery and targeting technologies for the ocular diseases

    PubMed Central

    Barar, Jaleh; Aghanejad, Ayuob; Fathi, Marziyeh; Omidi, Yadollah

    2016-01-01

    Introduction: Ocular targeted therapy has enormously been advanced by implementation of new methods of drug delivery and targeting using implantable drug delivery systems (DDSs) or devices (DDDs), stimuli-responsive advanced biomaterials, multimodal nanomedicines, cell therapy modalities and medical bioMEMs. These technologies tackle several ocular diseases such as inflammation-based diseases (e.g., scleritis, keratitis, uveitis, iritis, conjunctivitis, chorioretinitis, choroiditis, retinitis, retinochoroiditis), ocular hypertension and neuropathy, age-related macular degeneration and mucopolysaccharidosis (MPS) due to accumulation of glycosaminoglycans (GAGs). Such therapies appear to provide ultimate treatments, even though much more effective, yet biocompatible, noninvasive therapies are needed to control some disabling ocular diseases/disorders. Methods: In the current study, we have reviewed and discussed recent advancements on ocular targeted therapies. Results: On the ground that the pharmacokinetic and pharmacodynamic analyses of ophthalmic drugs need special techniques, most of ocular DDSs/devices developments have been designed to localized therapy within the eye. Application of advanced DDSs such as Subconjunctival insert/implants (e.g., latanoprost implant, Gamunex-C), episcleral implant (e.g., LX201), cationic emulsions (e.g., Cationorm™, Vekacia™, Cyclokat™), intac/punctal plug DDSs (latanoprost punctal plug delivery system, L-PPDS), and intravitreal implants (I-vitaion™, NT-501, NT- 503, MicroPump, Thethadur, IB-20089 Verisome™, Cortiject, DE-102, Retisert™, Iluvein™ and Ozurdex™) have significantly improved the treatment of ocular diseases. However, most of these DDSs/devices are applied invasively and even need surgical procedures. Of these, use of de novo technologies such as advanced stimuli-responsive nanomaterials, multimodal nanosystems (NSs)/nanoconjugates (NCs), biomacromolecualr scaffolds, and bioengineered cell therapies

  3. Advanced on-site power plant development technology program

    NASA Technical Reports Server (NTRS)

    1984-01-01

    A 30-cell, full area short stack containing advanced cell features was tested for 2900 hours. A stack acid addition approach was selected and will be evaluated on the stack at 5000 hours test time. A brassboard inverter was designed and fabrication was initiated. Evaluation of this brassboard inverter will take place in 1984. A Teflon coated commercial heat exchanger was selected as the preferred approach for the acid condenser. A reformer catalyst with significantly less pressure drop and equivalent performance relative to the 40-K baseline catalyst was selected for the development reformer. The early 40-kW field power plant history was reviewed and adjustments were made to the On-Site Technology Development Program to address critical component issues.

  4. Plan for advanced microelectronics processing technology application

    SciTech Connect

    Goland, A.N.

    1990-10-01

    The ultimate objective of the tasks described in the research agreement was to identify resources primarily, but not exclusively, within New York State that are available for the development of a Center for Advanced Microelectronics Processing (CAMP). Identification of those resources would enable Brookhaven National Laboratory to prepare a program plan for the CAMP. In order to achieve the stated goal, the principal investigators undertook to meet the key personnel in relevant NYS industrial and academic organizations to discuss the potential for economic development that could accompany such a Center and to gauge the extent of participation that could be expected from each interested party. Integrated of these discussions was to be achieved through a workshop convened in the summer of 1990. The culmination of this workshop was to be a report (the final report) outlining a plan for implementing a Center in the state. As events unfolded, it became possible to identify the elements of a major center for x-ray lithography on Lone Island at Brookhaven National Laboratory. The principal investigators were than advised to substitute a working document based upon that concept in place of a report based upon the more general CAMP workshop originally envisioned. Following that suggestion from the New York State Science and Technology Foundation, the principals established a working group consisting of representatives of the Grumman Corporation, Columbia University, the State University of New York at Stony Brook, and Brookhaven National Laboratory. Regular meetings and additional communications between these collaborators have produced a preproposal that constitutes the main body of the final report required by the contract. Other components of this final report include the interim report and a brief description of the activities which followed the establishment of the X-ray Lithography Center working group.

  5. Advanced Technology Solar Telescope Construction: Progress Report

    NASA Astrophysics Data System (ADS)

    Rimmele, Thomas R.; McMullin, J.; Keil, S.; Goode, P.; Knoelker, M.; Kuhn, J.; Rosner, R.; ATST Team

    2012-05-01

    The 4m Advance Technology Solar Telescope (ATST) on Haleakala will be the most powerful solar telescope and the world’s leading ground-based resource for studying solar magnetism that controls the solar wind, flares, coronal mass ejections and variability in the Sun’s output. The ATST will provide high resolution and high sensitivity observations of the dynamic solar magnetic fields throughout the solar atmosphere, including the corona at infrared wavelengths. With its 4 m aperture, ATST will resolve magnetic features at their intrinsic scales. A high order adaptive optics system delivers a corrected beam to the initial set of five state-of-the-art, facility class instrumentation located in the coude laboratory facility. Photopheric and chromospheric magnetometry is part of the key mission of four of these instruments. Coronal magnetometry and spectroscopy will be performed by two of these instruments at infrared wavelengths. The ATST project has transitioned from design and development to its construction phase. Site construction is expected to begin in April 2012. The project has awarded design and fabrication contracts for major telescope subsystems. A robust instrument program has been established and all instruments have passed preliminary design reviews or critical design reviews. A brief overview of the science goals and observational requirements of the ATST will be given, followed by a summary of the project status of the telescope and discussion of the approach to integrating instruments into the facility. The National Science Foundation (NSF) through the National Solar Observatory (NSO) funds the ATST Project. The NSO is operated under a cooperative agreement between the Association of Universities for Research in Astronomy, Inc. (AURA) and NSF.

  6. The Advanced Technology Solar Telescope enclosure

    NASA Astrophysics Data System (ADS)

    Phelps, L.; Barr, J.; Dalrymple, N.; Fraser, M.; Hubbard, R.; Wagner, J.; Warner, M.

    2006-06-01

    Telescope enclosure design is based on an increasingly standard set of criteria. Enclosures must provide failsafe protection in a harsh environment for an irreplaceable piece of equipment; must allow effective air flushing to minimize local seeing while still attenuating wind-induced vibration of the telescope; must reliably operate so that the dome is never the reason for observatory down time; must provide access to utilities, lifting devices and support facilities; and they must be affordable within the overall project budget. The enclosure for the Advanced Technology Solar Telescope (ATST) has to satisfy all these challenging requirements plus one more. To eliminate so-called external dome seeing, the exterior surfaces of the enclosure must be maintained at or just below ambient air temperature while being subjected to the full solar loading of an observing day. Further complicating the design of the ATST enclosure and support facilities are the environmental sensitivities and high construction costs at the selected site - the summit of Haleakala on the island of Maui, Hawaii. Previous development work has determined an appropriate enclosure shape to minimize solar exposure while allowing effective interior flushing, and has demonstrated the feasibility of controlling the exterior skin temperature with an active cooling system. This paper presents the evolution of the design since site selection and how the enclosure and associated thermal systems have been tailored to the particular climatic and terrain conditions of the site. Also discussed are load-reduction strategies that have been identified through thermal modeling, CFD modeling, and other analyses to refine and economize the thermal control systems.

  7. Microscale microbial fuel cells: Advances and challenges.

    PubMed

    Choi, Seokheun

    2015-07-15

    The next generation of sustainable energy could come from microorganisms; evidence that it can be seen with the given rise of Electromicrobiology, the study of microorganisms' electrical properties. Many recent advances in electromicrobiology stem from studying microbial fuel cells (MFCs), which are gaining acceptance as a future alternative "green" energy technology and energy-efficient wastewater treatment method. MFCs are powered by living microorganisms with clean and sustainable features; they efficiently catalyse the degradation of a broad range of organic substrates under natural conditions. There is also increasing interest in photosynthetic MFCs designed to harness Earth's most abundant and promising energy source (solar irradiation). Despite their vast potential and promise, however, MFCs and photosynthetic MFCs have not yet successfully translated into commercial applications because they demonstrate persistent performance limitations and bottlenecks associated with scaling up. Instead, microscale MFCs have received increasing attention as a unique platform for various applications such as powering small portable electronic elements in remote locations, performing fundamental studies of microorganisms, screening bacterial strains, and toxicity detection in water. Furthermore, the stacking of miniaturized MFCs has been demonstrated to offer larger power densities than a single macroscale MFC in terms of scaling up. In this overview, we discuss recent achievements in microscale MFCs as well as their potential applications. Further scientific and technological challenges are also reviewed.

  8. Advanced component technologies for energy-efficient turbofan engines

    NASA Technical Reports Server (NTRS)

    Saunders, N. T.

    1980-01-01

    The paper reviews NASA's Energy Efficient Engine Project which was initiated to provide the advanced technology base for a new generation of fuel-conservative engines for introduction into airline service by the late 1980s. Efforts in this project are directed at advancing engine component and systems technologies to a point of demonstrating technology-readiness by 1984. Early results indicate high promise in achieving most of the goals established in the project.

  9. Development of Advanced Deposition Technology for Microcrystalline Si Based Solar Cells and Modules: Final Technical Report, 1 May 2002-31 July 2004

    SciTech Connect

    Li, Y. M.

    2004-12-01

    The key objective of this subcontract was to take the first steps to extend the radio-frequency plasma-enhanced chemical vapor deposition (RF-PECVD) manufacturing technology of Energy Photovoltaics, Inc. (EPV), to the promising field of a-Si/nc-Si solar cell fabrication by demonstrating ''proof-of-concept'' devices of good efficiencies that previously were believed to be unobtainable in single-chamber reactors owing to contamination problems. A complementary goal was to find a new high-rate deposition method that can conceivably be deployed in large PECVD-type reactors. We emphasize that our goal was not to produce 'champion' devices of near-record efficiencies, but rather, to achieve modestly high efficiencies using a far simpler (cheaper) system, via practical processing methods and materials. To directly attack issues in solar-cell fabrication at EPV, the nc-Si thin films were studied almost exclusively in the p-i-n device configuration (as absorbers or i-layers), not as stand-alone films. Highly efficient, p-i-n type, nc-Si-based solar cells are generally grown on expensive, laboratory superstrates, such as custom ZnO/glass of high texture (granular surface) and low absorption. Also standard was the use of a highly effective back-reflector ZnO/Ag, where the ZnO can be surface-textured for efficient diffuse reflection. The high-efficiency ''champion'' devices made by the PECVD methods were invariably prepared in sophisticated (i.e., expensive), multi-chamber, or at least load-locked deposition systems. The electrode utilization efficiency, defined as the surface-area ratio of the powered electrode to that of the substrates, was typically low at about one (1:1). To evaluate the true potential of nc-Si absorbers for cost-competitive, commercially viable manufacturing of large-area PV modules, we took a more down-to-earth approach, based on our proven production of a-Si PV modules by a massively parallel batch process in single-chamber RF-PECVD systems, to the

  10. Technological Advances in Nursing Care Delivery.

    PubMed

    Sullivan, Debra Henline

    2015-12-01

    Technology is rapidly changing the way nurses deliver patient care. The Health Information Technology for Economic and Clinical Health Act of 2009 encourages health care providers to implement electronic health records for meaningful use of patient information. This development has opened the door to many technologies that use this information to streamline patient care. This article explores current and new technologies that nurses will be working with either now or in the near future.

  11. Funding Smart Classrooms: Administrating Technological Advances.

    ERIC Educational Resources Information Center

    Vartabedian, Robert A.

    According to the Northwestern University (2002) Web site, smart classrooms also can be called "electronic or technologically enhanced classrooms." Smart classrooms create new educational opportunities by integrating networking, computers, and audio visual technology. In this paper instructional technology, in particular, the "smart classroom" is…

  12. Advanced Teaching Methods for the Technology Classroom

    ERIC Educational Resources Information Center

    Petrina, Stephen

    2007-01-01

    Because of the nature of their subject, technology teachers have found ways to make learning active and exciting, often through new activities and projects that have real-world relevance. As technology fields grow, the success of technology teachers is tied in with innovation rather than the accomplishments of the past. This book provides a…

  13. Advanced technologies for turbomachinery systems: An overview

    NASA Technical Reports Server (NTRS)

    Hartmann, M. J.

    1982-01-01

    Turbomachinery system components and associated technologies are discussed. Specific technologies reviewed include the compressor, turbine, internal flow analysis methods, combustion, fuels, materials, structures, bearings, seals, and lubrication, dynamics and controls, and instrumentation. Analytical procedures as a path to improved performance are discussed. The strong interaction between the various technologies if turbomachinery performance gains are to be realized is reflected.

  14. Advanced technologies for NASA space programs

    NASA Technical Reports Server (NTRS)

    Krishen, Kumar

    1991-01-01

    A review of the technology requirements for future space programs is presented. The technologies are emphasized with a discussion of their mission impact. Attention is given to automation and robotics, materials, information acquisition/processing display, nano-electronics/technology, superconductivity, and energy generation and storage.

  15. Advanced on-site power plant development technology program

    NASA Astrophysics Data System (ADS)

    1989-09-01

    The purpose of the technical effort was to establish a technology base for 200-kW on-site fuel cell power plants. It was conducted in two phases: (1) Component evaluation; and (2) Full-scale system verification. This contract was supplemented by a Gas Research Institute (GRI) contract which was conducted in the 1981 to 1986 time period. This GRI contract concentrated on 200-kW scale component design, thermal management/water treatment system analysis and redesign and advanced DC/AC inverter development. The component evaluation phase generally included subscale component tests, scale-up to full-size 200-kW hardware and full-size hardware tests of the cell stack (in Tasks 1 and 2), the power conditioner (in Task 3), the heat exchangers and ancillary components (in Task 4), and the fuel processor (in Task 5). The full-size cell stack, fuel processor, heat exchangers, and ancillary components from the component development tasks were integrated into a dc system called the Verification Test Article (VTA). The VTA which was fabricated and tested under Task 7 allowed for system integration issues associated with the cell stack, fuel processor, thermal management, and water treatment subsystems to be explored under conditions similar to an actual fuel cell power plant. Key accomplishments of this contract are described.

  16. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2003-11-15

    The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (a) Solid-solid separation (b) Solid-liquid separation (c) Chemical/Biological Extraction (d) Modeling and Control, and (e) Environmental Control. Distribution of funds is being handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. The first of these solicitations, referred to as the CAST II-Round 1 RFP, was issued on October 28, 2002. Thirty-eight proposals were received by the December 10, 2002 deadline for this RFP-eleven (11) Solid-Solid Separation, seven (7) Solid-Liquid Separation, ten (10) Chemical/Biological Extraction, six (6) Modeling & Control and four (4) Environmental Control. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. This process took some 7 months to complete but 17 projects (one joint) were in place at the constituent universities (three at Virginia Tech, two at West Virginia University, three at University of Kentucky

  17. Advanced conversion technologies for small-scale remote power systems

    SciTech Connect

    Lamp, T.R.

    1996-12-31

    Forest fires that endangered remote US Air Force sites equipped with radioisotope thermoelectric generators (RTGs) prompted the assessment of power generating systems that could be substituted for RTGs in small scale (10--120 watt) applications. Other non-RTG sites were also studied during the assessment. The power system assessment was conducted by the US Air Forces` Wright Laboratory and included the evaluation of engine-driven generators, solar, wind generators, propane thermoelectric generators (TEGs), batteries, fuel cells, and power systems based on advanced conversion technologies; such as, thermionics, free piston Stirling Engines (FPSE), alkali metal thermoelectric conversion (AMTEC), and thermophotovoltaics (TPV). The assessment team concluded that continued use of the RTGs is clearly the safest, most reliable, and most economical approach to supplying electrical power for remote, difficult to access locations. If political considerations force the replacement of the RTGs, the likely replacement is a hybrid system consisting of solar-PV with a propane-TEG for off-solar times. The transport of combustible fuels in Arctic environments is extremely expensive. It is this high logistics cost that signaled the need to consider the option of more efficient and cost effective power sources for the remote, Arctic applications. This paper summarizes the assessment of some of the more attractive power systems that are based on the advanced conversion technologies of AMTEC, TPV and FPSE.

  18. TECHNOLOGY SUMMARY ADVANCING TANK WASTE RETRIEVAL AND PROCESSING

    SciTech Connect

    SAMS TL; MENDOZA RE

    2010-08-11

    This technology overview provides a high-level summary of technologies being investigated and developed by Washington River Protection Solutions (WRPS) to advance Hanford Site tank waste retrieval and processing. Technology solutions are outlined, along with processes and priorities for selecting and developing them.

  19. Advancing Professionalism in Technology Education. 48th Yearbook, 1999.

    ERIC Educational Resources Information Center

    Gilberti, Anthony F., Ed.; Rouch, David L., Ed.

    This yearbook contains 14 chapters, each by different authors, collected to assist in advancing professionalism within technology education. The 14 chapters are organized in five sections. Section 1: The Need for Professionalism in Technology Education contains "The Need for Professionalism in Technology Education: Challenges for the Future"…

  20. Application of advanced technologies to future military transports

    NASA Technical Reports Server (NTRS)

    Clark, Rodney L.; Lange, Roy H.; Wagner, Richard D.

    1990-01-01

    Long range military transport technologies are addressed with emphasis of defining the potential benefits of the hybrid laminar flow control (HLFC) concept currently being flight tested. Results of a 1990's global range transport study are presented showing the expected payoff from application of advanced technologies. Technology forecast for military transports is also presented.

  1. TECHNOLOGY SUMMARY ADVANCING TANK WASTE RETREIVAL AND PROCESSING

    SciTech Connect

    SAMS TL

    2010-07-07

    This technology overview provides a high-level summary of technologies being investigated and developed by Washington River Protection Solutions (WRPS) to advance Hanford Site tank waste retrieval and processing. Technology solutions are outlined, along with processes and priorities for selecting and developing them.

  2. 2004 Physics and Advanced Technologies In the News

    SciTech Connect

    Hazi, A

    2005-11-01

    Several outstanding research activities in the Physics and Advanced Technology Directorate in 2004 were featured in ''Science & Technology Review'', the monthly publication of the Lawrence Livermore National Laboratory. Reprints of those articles accompany this report. Here we summarize other science and technology highlights, as well as the awards and recognition received by members of the Directorate in 2004.

  3. Advanced High Pressure O2/H2 Technology

    NASA Technical Reports Server (NTRS)

    Morea, S. F. (Editor); Wu, S. T. (Editor)

    1985-01-01

    Activities in the development of advanced high pressure oxygen-hydrogen stage combustion rocket engines are reported. Particular emphasis is given to the Space Shuttle main engine. The areas of engine technology discussed include fracture and fatigue in engine components, manufacturing and producibility engineering, materials, bearing technology, structure dynamics, fluid dynamics, and instrumentation technology.

  4. Advances in culture and manipulation of human pluripotent stem cells.

    PubMed

    Qian, X; Villa-Diaz, L G; Krebsbach, P H

    2013-11-01

    Recent advances in the understanding of pluripotent stem cell biology and emerging technologies to reprogram somatic cells to a stem cell-like state are helping bring stem cell therapies for a range of human disorders closer to clinical reality. Human pluripotent stem cells (hPSCs) have become a promising resource for regenerative medicine and research into early development because these cells are able to self-renew indefinitely and are capable of differentiation into specialized cell types of all 3 germ layers and trophoectoderm. Human PSCs include embryonic stem cells (hESCs) derived from the inner cell mass of blastocyst-stage embryos and induced pluripotent stem cells (hiPSCs) generated via the reprogramming of somatic cells by the overexpression of key transcription factors. The application of hiPSCs and the finding that somatic cells can be directly reprogrammed into different cell types will likely have a significant impact on regenerative medicine. However, a major limitation for successful therapeutic application of hPSCs and their derivatives is the potential xenogeneic contamination and instability of current culture conditions. This review summarizes recent advances in hPSC culture and methods to induce controlled lineage differentiation through regulation of cell-signaling pathways and manipulation of gene expression as well as new trends in direct reprogramming of somatic cells.

  5. Managing the Perception of Advanced Technology Risks in Mission Proposals

    NASA Technical Reports Server (NTRS)

    Bellisario, Sebastian Nickolai

    2012-01-01

    Through my work in the project proposal office I became interested in how technology advancement efforts affect competitive mission proposals. Technology development allows for new instruments and functionality. However, including technology advancement in a mission proposal often increases perceived risk. Risk mitigation has a major impact on the overall evaluation of the proposal and whether the mission is selected. In order to evaluate the different approaches proposals took I compared the proposals claims of heritage and technology advancement to the sponsor feedback provided in the NASA debriefs. I examined a set of Discovery 2010 Mission proposals to draw patterns in how they were evaluated and come up with a set of recommendations for future mission proposals in how they should approach technology advancement to reduce the perceived risk.

  6. Advanced technology for America's future in space

    NASA Technical Reports Server (NTRS)

    1990-01-01

    In response to Recommendation 8 of the Augustine Committee Report, NASA's Office of Aeronautics, Exploration and Technology (OAET) developed a proposed 'Integrated Technology Plan for the Civil Space Program' that entails substantial changes in the processes, structure and the content of NASA's space research and technology program. The Space Systems and Technology Advisory Committee (SSTAC, a subcommittee of the NASA Advisory Committee) and several other senior, expert, informed advisory groups conducted a review of NASA's proposed Integrated Technology Plan (ITP). This review was in response to the specific request in Recommendation 8 that 'NASA utilize an expert, outside review process, managed from headquarters, to assist in the allocation of technology funds'. This document, the final report from that review, addresses: (1) summary recommendations; (2) mission needs; (3) the integrated technology plan; (4) summary reports of the technical panels; and (5) conclusions and observations.

  7. Advanced information processing system for advanced launch system: Hardware technology survey and projections

    NASA Technical Reports Server (NTRS)

    Cole, Richard

    1991-01-01

    The major goals of this effort are as follows: (1) to examine technology insertion options to optimize Advanced Information Processing System (AIPS) performance in the Advanced Launch System (ALS) environment; (2) to examine the AIPS concepts to ensure that valuable new technologies are not excluded from the AIPS/ALS implementations; (3) to examine advanced microprocessors applicable to AIPS/ALS, (4) to examine radiation hardening technologies applicable to AIPS/ALS; (5) to reach conclusions on AIPS hardware building blocks implementation technologies; and (6) reach conclusions on appropriate architectural improvements. The hardware building blocks are the Fault-Tolerant Processor, the Input/Output Sequencers (IOS), and the Intercomputer Interface Sequencers (ICIS).

  8. Schedule Risks Due to Delays in Advanced Technology Development

    NASA Technical Reports Server (NTRS)

    Reeves, John D. Jr.; Kayat, Kamal A.; Lim, Evan

    2008-01-01

    This paper discusses a methodology and modeling capability that probabilistically evaluates the likelihood and impacts of delays in advanced technology development prior to the start of design, development, test, and evaluation (DDT&E) of complex space systems. The challenges of understanding and modeling advanced technology development considerations are first outlined, followed by a discussion of the problem in the context of lunar surface architecture analysis. The current and planned methodologies to address the problem are then presented along with sample analyses and results. The methodology discussed herein provides decision-makers a thorough understanding of the schedule impacts resulting from the inclusion of various enabling advanced technology assumptions within system design.

  9. Advances in stem cell therapy.

    PubMed

    Pérez López, Silvia; Otero Hernández, Jesús

    2012-01-01

    Since the beginning of stem cell biology, considerable effort has been focused in the translation of scientific insights into new therapies. Cell-based assays represent a new strategy for organ and tissue repair in several pathologies. Moreover, alternative treatment strategies are urgently needed due to donor organ shortage that costs many lives every year and results in lifelong immunosuppression. At the moment, only the use of hematopoietic stem cells is considered as the standard for the treatment of malignant and genetic bone marrow disorders, being all other stem cell applications highly experimental. The present chapter tries to summarize some ongoing approaches of stem cell regenerative medicine and also introduces recent findings from published studies and trials conducted in various tissues such as skeletal muscle, liver and lung.

  10. Technology advancement of the electrochemical CO2 concentrating process

    NASA Technical Reports Server (NTRS)

    Schubert, F. H.; Heppner, D. B.; Hallick, T. M.; Woods, R. R.

    1979-01-01

    Two multicell, liquid-cooled, advanced electrochemical depolarized carbon dioxide concentrator modules were fabricated. The cells utilized advanced, lightweight, plated anode current collectors, internal liquid cooling and lightweight cell frames. Both were designed to meet the carbon dioxide removal requirements of one-person, i.e., 1.0 kg/d (2.2 lb/d).

  11. A review of advanced manufacturing technology

    NASA Astrophysics Data System (ADS)

    Broughton, T.

    1981-03-01

    Joining techniques, hot forming technology, forging technology, investment casting, small cooling hole manufacturing, combustor technology, quality assurance, and chip forming machining of gas turbine engine components are discussed. Electron and laser beam welding; laser hard facing techniques; automatic TIG and plasma welding; diffusion brazing of titanium and nickel alloys; heated die forming: blow forming; superplastic forming; fan and compressor blade forging; and wheel and disk forging from powder superalloys are described.

  12. Advanced processing technology for high-efficiency thin-film CuInSe{sub 2} solar cells. Annual subcontract report, 1 March 1992--28 February 1993

    SciTech Connect

    Morel, D.L.; Attar, G.; Karthikeyan, S.; Muthaiah, A.; Zafar, A.

    1993-08-01

    This report describes work to develop novel fabrication for CuInSe{sub 2} (CIS) solar cells that will result in improved performance and cost effectiveness at the manufacturing level. The primary approach involves all solid-state processing for CIS. This was augmented by work to provide novel alternatives for the formation of the window layer/heterojunction contact. Inherent to the project was the need to develop a generic understanding of the relationship between processing and performance so that broad-based transfer to industry can be facilitated. We achieved good-electronic-quality CIS by the use of two selenization procedures for predeposited metal layers. We achieved good stoichiometry throughout the bulk of the film, attained grain sizes of up to 1 {mu}m, and measured electron mobilities of up to 60 cm{sup 2}V-s. However, there is a complex relationship between grain size, adhesion, and performance. Our primary approach to characterization was to fabricate ZnO/CIS test devices and measure as many properties as possible in device format. We are also developing reactive sputtering of ZnO as an alternative window layer technology.

  13. Technology Readiness Levels for Advanced Nuclear Fuels and Materials Development

    SciTech Connect

    Jon Carmack

    2014-01-01

    The Technology Readiness Level (TRL) process is used to quantitatively assess the maturity of a given technology. The TRL process has been developed and successfully used by the Department of Defense (DOD) for development and deployment of new technology and systems for defense applications. In addition, NASA has also successfully used the TRL process to develop and deploy new systems for space applications. Advanced nuclear fuels and materials development is a critical technology needed for closing the nuclear fuel cycle. Because the deployment of a new nuclear fuel forms requires a lengthy and expensive research, development, and demonstration program, applying the TRL concept to the advanced fuel development program is very useful as a management and tracking tool. This report provides definition of the technology readiness level assessment process as defined for use in assessing nuclear fuel technology development for the Advanced Fuel Campaign (AFC).

  14. Advances in Perovskite Solar Cells

    PubMed Central

    Zuo, Chuantian; Bolink, Henk J.; Han, Hongwei; Huang, Jinsong

    2016-01-01

    Organolead halide perovskite materials possess a combination of remarkable optoelectronic properties, such as steep optical absorption edge and high absorption coefficients, long charge carrier diffusion lengths and lifetimes. Taken together with the ability for low temperature preparation, also from solution, perovskite‐based devices, especially photovoltaic (PV) cells have been studied intensively, with remarkable progress in performance, over the past few years. The combination of high efficiency, low cost and additional (non‐PV) applications provides great potential for commercialization. Performance and applications of perovskite solar cells often correlate with their device structures. Many innovative device structures were developed, aiming at large‐scale fabrication, reducing fabrication cost, enhancing the power conversion efficiency and thus broadening potential future applications. This review summarizes typical structures of perovskite solar cells and comments on novel device structures. The applications of perovskite solar cells are discussed. PMID:27812475

  15. An overview of DARPA's advanced space technology program

    NASA Astrophysics Data System (ADS)

    Nicastri, E.; Dodd, J.

    1993-02-01

    The Defense Advanced Research Projects Agency (DARPA) is the central research and development organization of the DoD and, as such, has the primary responsibility for the maintenance of U.S. technological superiority over potential adversaries. DARPA's programs focus on technology development and proof-of-concept demonstrations of both evolutionary and revolutionary approaches for improved strategic, conventional, rapid deployment and sea power forces, and on the scientific investigation into advanced basic technologies of the future. DARPA can move quickly to exploit new ideas and concepts by working directly with industry and universities. For four years, DARPA's Advanced Space Technology Program (ASTP) has addressed various ways to improve the performance of small satellites and launch vehicles. The advanced technologies that are being and will be developed by DARPA for small satellites can be used just as easily on large satellites. The primary objective of the ASTP is to enhance support to operational commanders by developing and applying advanced technologies that will provide cost-effective, timely, flexible, and responsive space systems. Fundamental to the ASTP effort is finding new ways to do business with the goal of quickly inserting new technologies into DoD space systems while reducing cost. In our view, these methods are prime examples of what may be termed 'technology leveraging.' The ASTP has initiated over 50 technology projects, many of which were completed and transitioned to users. The objectives are to quickly qualify these higher risk technologies for use on future programs and reduce the risk of inserting these technologies into major systems, and to provide the miniaturized systems that would enable smaller satellites to have significant - rather than limited - capability. Only a few of the advanced technologies are described, the majority of which are applicable to both large and small satellites.

  16. Advancing Distance Education Programs with Ordinary Technologies.

    ERIC Educational Resources Information Center

    Lemke, Randal A.; And Others

    This paper begins by arguing that access to education for those who do not attend classes on campus can be a question of their access to technology, i.e., the higher (or more exotic) the technology, the fewer the students who have means to use it. Almost universal access via the postal service is discussed in terms of speed, as compared with…

  17. MMIC technology for advanced space communications systems

    NASA Technical Reports Server (NTRS)

    Downey, A. N.; Connolly, D. J.; Anzic, G.

    1984-01-01

    The current NASA program for 20 and 30 GHz monolithic microwave integrated circuit (MMIC) technology is reviewed. The advantages of MMIC are discussed. Millimeter wavelength MMIC applications and technology for communications systems are discussed. Passive and active MMIC compatible components for millimeter wavelength applications are investigated. The cost of a millimeter wavelength MMIC's is projected.

  18. Advances in Technology, Education and Development

    ERIC Educational Resources Information Center

    Kouwenhoven, Wim, Ed.

    2009-01-01

    From 3rd to 5th March 2008 the International Association of Technology, Education and Development organised its International Technology, Education and Development Conference in Valencia, Spain. Over a hundred papers were presented by participants from a great variety of countries. Summarising, this book provides a kaleidoscopic view of work that…

  19. Advanced manufacturing technologies on color plasma displays

    NASA Astrophysics Data System (ADS)

    Betsui, Keiichi

    2000-06-01

    The mass production of the color plasma display started from 1996. However, since the price of the panel is still expensive, PDPs are not in widespread use at home. It is necessary to develop the new and low-cost manufacturing technologies to reduce the price of the panel. This paper describes some of the features of new fabrication technologies of PDPs.

  20. Organizational Considerations for Advanced Manufacturing Technology

    ERIC Educational Resources Information Center

    DeRuntz, Bruce D.; Turner, Roger M.

    2003-01-01

    In the last several decades, the United States has experienced a decline in productivity, while the world has seen a maturation of the global marketplace. Nations have moved manufacturing strategy and process technology issues to the top of management priority lists. The issues surrounding manufacturing technologies and their implementations have…

  1. Advanced composite airframe program: Today's technology

    NASA Technical Reports Server (NTRS)

    Good, Danny E.; Mazza, L. Thomas

    1988-01-01

    The Advanced Composite Airframe Program (ACAP) was undertaken to demonstrate the advantages of the application of advanced composite materials and structural design concepts to the airframe structure on helicopters designed to stringent military requirements. The primary goals of the program were the reduction of airframe production costs and airframe weight by 17 and 22 percent respectively. The ACAP effort consisted of a preliminary design phase, detail design, and design support testing, full-scale fabrication, laboratory testing, and a ground/flight test demonstration. Since the completion of the flight test demonstration programs follow-on efforts were initiated to more fully evaluate a variety of military characteristics of the composite airframe structures developed under the original ACAP advanced development contracts. An overview of the ACAP program is provided and some of the design features, design support testing, manufacturing approaches, and the results of the flight test evaluation, as well as, an overview of Militarization Test and Evaluation efforts are described.

  2. Advances in ROADM technologies and subsystems

    NASA Astrophysics Data System (ADS)

    Eldada, Louay

    2005-09-01

    Until recently, reconfigurable optical add/drop multiplexer (ROADM) systems did not exist, their components were unselected, and their market was unclear. Today, every major system vendor has a ROADM offering, and a large number of component vendors have announced ROADM products based on a variety of technologies, some more mature than others. We review the different optical component technologies that have been developed for use in ROADM subsystems, and describe their principles of operation, designs, advantages, and challenges. The technology platforms that we cover include MEMS, liquid crystals (liquid crystal devices (LCD) and liquid crystal on silicon (LCoS) technologies), and monolithic and hybrid planar lightwave circuits (PLC) based on silica on silicon and polymer on silicon platforms. For each technology, we describe the corresponding ROADM subsystem architectures in terms of functionality, features, size, cost, and maturity.

  3. Advancing Sensor Technology for Aerospace Propulsion

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Mercer, Carolyn R.

    2002-01-01

    NASA's Stennis Space Center (SSC) and Glenn Research Center (GRC) participate in the development of technologies for propulsion testing and propulsion applications in air and space transportation. Future transportation systems and the test facilities needed to develop and sustain them are becoming increasingly complex. Sensor technology is a fundamental pillar that makes possible development of complex systems that must operate in automatic mode (closed loop systems), or even in assisted-autonomous mode (highly self-sufficient systems such as planetary exploration spacecraft). Hence, a great deal of effort is dedicated to develop new sensors and related technologies to be used in research facilities, test facilities, and in vehicles and equipment. This paper describes sensor technologies being developed and in use at SSC and GRC, including new technologies in integrated health management involving sensors, components, processes, and vehicles.

  4. Value analysis for advanced technology products

    NASA Astrophysics Data System (ADS)

    Soulliere, Mark

    2011-03-01

    Technology by itself can be wondrous, but buyers of technology factor in the price they have to pay along with performance in their decisions. As a result, the ``best'' technology may not always win in the marketplace when ``good enough'' can be had at a lower price. Technology vendors often set pricing by ``cost plus margin,'' or by competitors' offerings. What if the product is new (or has yet to be invented)? Value pricing is a methodology to price products based on the value generated (e.g. money saved) by using one product vs. the next best technical alternative. Value analysis can often clarify what product attributes generate the most value. It can also assist in identifying market forces outside of the control of the technology vendor that also influence pricing. These principles are illustrated with examples.

  5. Advanced Microelectronics Technologies for Future Small Satellite Systems

    NASA Technical Reports Server (NTRS)

    Alkalai, Leon

    1999-01-01

    Future small satellite systems for both Earth observation as well as deep-space exploration are greatly enabled by the technological advances in deep sub-micron microelectronics technologies. Whereas these technological advances are being fueled by the commercial (non-space) industries, more recently there has been an exciting new synergism evolving between the two otherwise disjointed markets. In other words, both the commercial and space industries are enabled by advances in low-power, highly integrated, miniaturized (low-volume), lightweight, and reliable real-time embedded systems. Recent announcements by commercial semiconductor manufacturers to introduce Silicon On Insulator (SOI) technology into their commercial product lines is driven by the need for high-performance low-power integrated devices. Moreover, SOI has been the technology of choice for many space semiconductor manufacturers where radiation requirements are critical. This technology has inherent radiation latch-up immunity built into the process, which makes it very attractive to space applications. In this paper, we describe the advanced microelectronics and avionics technologies under development by NASA's Deep Space Systems Technology Program (also known as X2000). These technologies are of significant benefit to both the commercial satellite as well as the deep-space and Earth orbiting science missions. Such a synergistic technology roadmap may truly enable quick turn-around, low-cost, and highly capable small satellite systems for both Earth observation as well as deep-space missions.

  6. Technological advances in renal replacement therapy: five years and beyond.

    PubMed

    Rastogi, Anjay; Nissenson, Allen R

    2009-12-01

    The worldwide epidemic of chronic kidney disease shows no signs of abating in the near future. Current dialysis forms of renal replacement therapy (RRT), even though successful in sustaining life and improving quality of life somewhat for patients with ESRD, have many limitations that result in still unacceptably high morbidity and mortality. Transplantation is an excellent option but is limited by the scarcity of organs. An ideal form of RRT would mimic the functions of natural kidneys and be transparent to the patient, as well as affordable to society. Recent advances in technology, although generally in early stages of development, might achieve these goals. The application of nanotechnology, microfluidics, bioreactors with kidney cells, and miniaturized sorbent systems to regenerate dialysate makes clinical reality seem closer than ever before. Finally, stem cells hold much promise, both for kidney disease and as a source of tissues and organs. In summary, nephrology is at an exciting crossroad with the application of innovative and novel technologies to RRT that hold considerable promise for the near future.

  7. Advanced Platform Systems Technology study. Volume 3: Supporting data

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The overall study effort proceeded from the identification of 106 technology topics to the selection of 5 for detail trade studies. The technical issues and options were evaluated through the trade process. Finally, individual consideration was given to costs and benefits for the technologies identified for advancement. Eight priority technology items were identified for advancement. Supporting data generated during the trade selection and trade study process were presented. Space platform requirements, trade study and cost benefits analysis, and technology advancement planning are advanced. The structured approach used took advantage of a number of forms developed to ensure that a consistent approach was employed by each of the diverse specialists that participated. These forms were an intrinsic part of the study protocol.

  8. Advanced Technology Display House. Volume 2: Energy system design concepts

    NASA Technical Reports Server (NTRS)

    Maund, D. H.

    1981-01-01

    The preliminary design concept for the energy systems in the Advanced Technology Display House is analyzed. Residential energy demand, energy conservation, and energy concepts are included. Photovoltaic arrays and REDOX (reduction oxidation) sizes are discussed.

  9. Advanced Technology Display House. Volume 1: Project Summary and Procedures

    NASA Technical Reports Server (NTRS)

    Maund, D. H.

    1981-01-01

    The Advanced Technology Display House (ATDH) project is described. Tasks are defined in the areas of energy demand, water demand, sewage treatment, electric power, plumbing, lighting, heating, and air conditioning. Energy, water, and sewage systems are defined.

  10. Advanced Materials in Support of EERE Needs to Advance Clean Energy Technologies Program Implementation

    SciTech Connect

    Liby, Alan L; Rogers, Hiram

    2013-10-01

    The goal of this activity was to carry out program implementation and technical projects in support of the ARRA-funded Advanced Materials in Support of EERE Needs to Advance Clean Energy Technologies Program of the DOE Advanced Manufacturing Office (AMO) (formerly the Industrial Technologies Program (ITP)). The work was organized into eight projects in four materials areas: strategic materials, structural materials, energy storage and production materials, and advanced/field/transient processing. Strategic materials included work on titanium, magnesium and carbon fiber. Structural materials included work on alumina forming austentic (AFA) and CF8C-Plus steels. The advanced batteries and production materials projects included work on advanced batteries and photovoltaic devices. Advanced/field/transient processing included work on magnetic field processing. Details of the work in the eight projects are available in the project final reports which have been previously submitted.

  11. Principles of Motor Unit Physiology Evolve With Advances in Technology.

    PubMed

    Farina, Dario; Negro, Francesco; Muceli, Silvia; Enoka, Roger M

    2016-03-01

    Movements are generated by the coordinated activation of motor units. Recent technological advances have made it possible to identify the concurrent activity of several tens of motor units, in contrast with much smaller samples available in classic studies. We discuss how these advances in technology have enabled the development of a population perspective of how the central nervous system controls motor unit activity and thereby the forces exerted by muscles.

  12. Technology advances for Space Shuttle processing

    NASA Technical Reports Server (NTRS)

    Wiskerchen, M. J.; Mollakarimi, C. L.

    1988-01-01

    One of the major initial tasks of the Space Systems Integration and Operations Research Applications (SIORA) Program was the application of automation and robotics technology to all aspects of the Shuttle tile processing and inspection system. The SIORA Program selected a nonlinear systems engineering methodology which emphasizes a team approach for defining, developing, and evaluating new concepts and technologies for the operational system. This is achieved by utilizing rapid prototyping testbeds whereby the concepts and technologies can be iteratively tested and evaluated by the team. The present methodology has clear advantages for the design of large complex systems as well as for the upgrading and evolution of existing systems.

  13. Application of advanced technology to space automation

    NASA Technical Reports Server (NTRS)

    Schappell, R. T.; Polhemus, J. T.; Lowrie, J. W.; Hughes, C. A.; Stephens, J. R.; Chang, C. Y.

    1979-01-01

    Automated operations in space provide the key to optimized mission design and data acquisition at minimum cost for the future. The results of this study strongly accentuate this statement and should provide further incentive for immediate development of specific automtion technology as defined herein. Essential automation technology requirements were identified for future programs. The study was undertaken to address the future role of automation in the space program, the potential benefits to be derived, and the technology efforts that should be directed toward obtaining these benefits.

  14. Advances in induction-heated plasma torch technology

    NASA Technical Reports Server (NTRS)

    Poole, J. W.; Vogel, C. E.

    1972-01-01

    Continuing research has resulted in significant advances in induction-heated plasma torch technology which extend and enhance its potential for broad range of uses in chemical processing, materials development and testing, and development of large illumination sources. Summaries of these advances are briefly described.

  15. Advanced Education and Technology Business Plan, 2011-14

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2011

    2011-01-01

    Advanced Education and Technology's mission is to lead the development of a knowledge-driven future through a dynamic and integrated advanced learning and innovation system. Its core businesses are to: (1) provide strategic leadership for Campus Alberta and Alberta Innovates; and (2) engage learners, industry and the community in learning…

  16. The ECLSS Advanced Automation Project Evolution and Technology Assessment

    NASA Technical Reports Server (NTRS)

    Dewberry, Brandon S.; Carnes, James R.; Lukefahr, Brenda D.; Rogers, John S.; Rochowiak, Daniel M.; Mckee, James W.; Benson, Brian L.

    1990-01-01

    Viewgraphs on Environmental Control and Life Support System (ECLSS) advanced automation project evolution and technology assessment are presented. Topics covered include: the ECLSS advanced automation project; automatic fault diagnosis of ECLSS subsystems descriptions; in-line, real-time chemical and microbial fluid analysis; and object-oriented, distributed chemical and microbial modeling of regenerative environmental control systems description.

  17. Fuel cell technology program

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The results of a solid polymer electrolyte fuel cell development program are summarized. A base line design was defined, and materials and components of the base line configuration were fabricated and tested. Concepts representing base line capability extensions in the areas of life, power, specific weight and volume, versatility of operation, field maintenance, and thermal control were identified and evaluated. Liaison and coordination with space shuttle contractors resulted in the exchange of engineering data.

  18. Advanced Membrane Separation Technologies for Energy Recovery

    SciTech Connect

    2009-05-01

    This factsheet describes a research project whose goal is to develop novel materials for use in membrane separation technologies for the recovery of waste energy and water from industrial process streams.

  19. Prostate Cancer Stem Cells: Research Advances

    PubMed Central

    Jaworska, Dagmara; Król, Wojciech; Szliszka, Ewelina

    2015-01-01

    Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. PMID:26593898

  20. Development of advanced fuel cell system

    NASA Technical Reports Server (NTRS)

    Grevstad, P. E.

    1972-01-01

    Weight, life and performance characteristics optimization of hydrogen-oxygen fuel cell power systems were considered. A promising gold alloy cathode catalyst was identified and tested in a cell for 5,000 hours. The compatibility characteristics of candidate polymer structural materials were measured after exposure to electrolyte and water vapor for 8,000 hours. Lightweight cell designs were prepared and fabrication techniques to produce them were developed. Testing demonstrated that predicted performance was achieved. Lightweight components for passive product water removal and evaporative cooling of cells were demonstrated. Systems studies identified fuel cell powerplant concepts for meeting the requirements of advanced spacecraft.

  1. Prostate Cancer Stem Cells: Research Advances.

    PubMed

    Jaworska, Dagmara; Król, Wojciech; Szliszka, Ewelina

    2015-01-01

    Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease.

  2. Advanced technology for satellite data collection systems

    NASA Technical Reports Server (NTRS)

    Cote, C. E.; Painter, J. E.

    1981-01-01

    Technological developments in satellite data collection are aimed at relieving constraints of existing systems to permit expanded capability at lower costs in future operations. Constraints imposed by the limited electromagnetic spectrum available in the UHF band and the cost of user equipment are principal targets for improvement through technology. This paper describes ongoing developmental activities in system and component areas which will become available for the next generation of operations.

  3. Technology advancement of the electrochemical CO2 concentrating process

    NASA Technical Reports Server (NTRS)

    Schubert, F. H.; Woods, R. R.; Hallick, T. M.; Heppner, D. B.

    1977-01-01

    A five-cell, liquid-cooled advanced electrochemical depolarized carbon dioxide concentrator module was fabricated. The cells utilized the advanced, lightweight, plated anode current collector concept and internal liquid-cooling. The five cell module was designed to meet the carbon dioxide removal requirements of one man and was assembled using plexiglass endplates. This one-man module was tested as part of an integrated oxygen generation and recovery subsystem.

  4. Infrared detectors: Advances, challenges and new technologies

    NASA Astrophysics Data System (ADS)

    Karim, Amir; Andersson, Jan Y.

    2013-12-01

    Human knowledge of infrared (IR) radiation is about 200 years old. However it was in the late 20th century that we developed a wide range of smart technologies for detection and started to take advantage for our benefit. Today IR detector technology is in its 3rd generation and comes with challenging demands. Based on the propagation of IR radiation through free space it is divided into different transmission windows. The most interesting for thermal imaging are the mid-wave IR (MWIR) and the long-wave IR (LW IR). Infrared detectors for thermal imaging have a number of applications in industry, security, search & rescue, surveillance, medicine, research, meteorology, climatology and astronomy. Currently high-performance IR imaging technology is mainly based on epitaxially grown structures of the small-bandgap bulk alloy mercury-cadmium-telluride (MCT), indium antimonide (InSb) and GaAs based quantum-well infrared photodetectors (QWIPs), depending on the application and wavelength range. However, they operate at low temperatures requiring costly and bulky cryogenic systems. In addition there is always a need for better performance, which generates possibilities for developing new technologies. Some emerging technologies are quantum dot infrared photodetectors (QDIPs), type-II strained layer super-lattice, and QDIPs with type-II band alignment. In this report a brief review of the current and new technologies for high performance IR detectors, will be presented.

  5. Advanced Technology Spark-Ignition Aircraft Piston Engine Design Study

    NASA Technical Reports Server (NTRS)

    Stuckas, K. J.

    1980-01-01

    The advanced technology, spark ignition, aircraft piston engine design study was conducted to determine the improvements that could be made by taking advantage of technology that could reasonably be expected to be made available for an engine intended for production by January 1, 1990. Two engines were proposed to account for levels of technology considered to be moderate risk and high risk. The moderate risk technology engine is a homogeneous charge engine operating on avgas and offers a 40% improvement in transportation efficiency over present designs. The high risk technology engine, with a stratified charge combustion system using kerosene-based jet fuel, projects a 65% improvement in transportation efficiency. Technology enablement program plans are proposed herein to set a timetable for the successful integration of each item of required advanced technology into the engine design.

  6. Standards Advisor-Advanced Information Technology for Advanced Information Delivery

    NASA Technical Reports Server (NTRS)

    Hawker, J. Scott

    2003-01-01

    Developers of space systems must deal with an increasing amount of information in responding to extensive requirements and standards from numerous sources. Accessing these requirements and standards, understanding them, comparing them, negotiating them and responding to them is often an overwhelming task. There are resources to aid the space systems developer, such as lessons learned and best practices. Again, though, accessing, understanding, and using this information is often more difficult than helpful. This results in space systems that: 1. Do not meet all their requirements. 2. Do not incorporate prior engineering experience. 3. Cost more to develop. 4. Take longer to develop. The NASA Technical Standards Program (NTSP) web site at http://standards.nasa.gov has made significant improvements in making standards, lessons learned, and related material available to space systems developers agency-wide. The Standards Advisor was conceived to take the next steps beyond the current product, continuing to apply evolving information technology that continues to improve information delivery to space systems developers. This report describes the features of the Standards Advisor and suggests a technical approach to its development.

  7. Medical technology advances from space research.

    NASA Technical Reports Server (NTRS)

    Pool, S. L.

    1971-01-01

    NASA-sponsored medical R & D programs for space applications are reviewed with particular attention to the benefits of these programs to earthbound medical services and to the general public. Notable among the results of these NASA programs is an integrated medical laboratory equipped with numerous advanced systems such as digital biotelemetry and automatic visual field mapping systems, sponge electrode caps for electroencephalograms, and sophisticated respiratory analysis equipment.

  8. Underground communications and tracking technology advances

    SciTech Connect

    Fiscor, S.

    2007-03-15

    As the June 2009 deadline set by the MINER Act grows near, several technologies have emerged as possible options for communicating and tracking underground coal miners in the event of an emergency or disaster. NIOSH is currently deciding how best to invest $10 million assigned by Congress under an Emergency Supplementary Appropriations Act (ESA) to research and develop mine safety technology. Medium and ultra high frequency (UHF) systems seem to be leading the pack with radio frequency identification (RFID) tags serving as the tracking system. Wireless mesh systems can serve as a communications infrastructure and they can do much more. Even more technologies continue to emerge, such as inertial navigation tracking systems. Mines are discovering the wonders of modern voice and data communications underground. Still no one know if it is economically practical to design a system that will function after a coal mine explosion. From the nineteen systems submitted to MSHA's request for information (RFI), six systems were selected that represented most of the technologies that had been proposed: the Rajant Breadcrumb, Innovative Wireless, Concurrent Technologies/Time Domain, Transtek, Gamma Services, and the Kutta Consulting systems. They were tested at CONSOL Energy's McElroy mine in April 2006. MSHA felt that all of those systems needed a significant amount of work before they were ready for use in a underground coal mining environment. The agency continues to work with these, and other manufacturers, to assist in arranging for field demonstration and then to gain MSHA approval.

  9. A rotor technology assessment of the advancing blade concept

    NASA Technical Reports Server (NTRS)

    Pleasants, W. A.

    1983-01-01

    A rotor technology assessment of the Advancing Blade Concept (ABC) was conducted in support of a preliminary design study. The analytical methodology modifications and inputs, the correlation, and the results of the assessment are documented. The primary emphasis was on the high-speed forward flight performance of the rotor. The correlation data base included both the wind tunnel and the flight test results. An advanced ABC rotor design was examined; the suitability of the ABC for a particular mission was not considered. The objective of this technology assessment was to provide estimates of the performance potential of an advanced ABC rotor designed for high speed forward flight.

  10. Advanced High-Temperature Engine Materials Technology Progresses

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The objective of the Advanced High Temperature Engine Materials Technology Program (HITEMP) at the NASA Lewis Research Center is to generate technology for advanced materials and structural analysis that will increase fuel economy, improve reliability, extend life, and reduce operating costs for 21st century civil propulsion systems. The primary focus is on fan and compressor materials (polymer-matrix composites - PMC's), compressor and turbine materials (superalloys, and metal-matrix and intermetallic-matrix composites - MMC's and IMC's), and turbine materials (ceramic-matrix composites - CMC's). These advanced materials are being developed in-house by Lewis researchers and on grants and contracts.

  11. Advanced direct methanol fuel cells. Final report

    SciTech Connect

    Hamdan, Monjid; Kosek, John A.

    1999-11-01

    The goal of the program was an advanced proton-exchange membrane (PEM) for use as the electrolyte in a liquid feed direct methanol fuel cell which provides reduced methanol crossover while simultaneously providing high conductivity and low membrane water content. The approach was to use a membrane containing precross-linked fluorinated base polymer films and subsequently to graft the base film with selected materials. Over 80 different membranes were prepared. The rate of methanol crossover through the advanced membranes was reduced 90%. A 5-cell stack provided stable performance over a 100-hour life test. Preliminary cost estimates predicted a manufacturing cost at $4 to $9 per kW.

  12. Going forward with genetics: recent technological advances and forward genetics in mice.

    PubMed

    Moresco, Eva Marie Y; Li, Xiaohong; Beutler, Bruce

    2013-05-01

    Forward genetic analysis is an unbiased approach for identifying genes essential to defined biological phenomena. When applied to mice, it is one of the most powerful methods to facilitate understanding of the genetic basis of human biology and disease. The speed at which disease-causing mutations can be identified in mutagenized mice has been markedly increased by recent advances in DNA sequencing technology. Creating and analyzing mutant phenotypes may therefore become rate-limiting in forward genetic experimentation. We review the forward genetic approach and its future in the context of recent technological advances, in particular massively parallel DNA sequencing, induced pluripotent stem cells, and haploid embryonic stem cells.

  13. Advance Power Technology Demonstration on Starshine 3

    NASA Technical Reports Server (NTRS)

    Jenkins, Phillip; Scheiman, David; Wilt, David; Raffaelle, Ryne; Button, Robert; Smith, Mark; Kerslake, Thomas; Miller, Thomas

    2002-01-01

    The Starshine 3 satellite will carry several power technology demonstrations. Since Starshine 3 is primarily a passive experiment and does not need electrical power to successfully complete its mission, the requirement for a highly reliable power system is greatly reduced. This creates an excellent opportunity to test new power technologies. Several government and commercial interests have teamed up to provide Starshine 3 with a small power system using state-of-the-art components. Starshine 3 will also fly novel integrated microelectronic power supplies (IMPS) for evaluation.

  14. Advanced NDE Technologies for Powder Metal Components

    SciTech Connect

    Martin, P; Haskins, J; Thomas, G; Dolan, K

    2003-05-01

    Nondestructive evaluation encompasses numerous technologies that assess materials and determine important properties. This paper demonstrates the applicability of several of these technologies to the field of powder metallurgy. The usual application of nondestructive evaluation is to detect and quantify defects in fully sintered product. But probably its most appealing role is to sense problems earlier in the manufacturing process to avoid making defects at all. Also nondestructive evaluation can be incorporated into the manufacturing processes to monitor important parameters and control the processes to produce defect free product. Nondestructive evaluation can characterize powders, evaluate components in the green state, monitor the sintering process, and inspect the final component.

  15. [Technological advances and hospital-at-home care].

    PubMed

    Tibaldi, Vittoria; Aimonino Ricauda, Nicoletta; Rocco, Maurizio; Bertone, Paola; Fanton, Giordano; Isaia, Giancarlo

    2013-05-01

    Advances in the miniaturization and portability of diagnostic technologies, information technologies, remote monitoring, and long-distance care have increased the viability of home-based care, even for patients with serious conditions. Telemedicine and teleradiology projects are active at the Hospital at Home Service of Torino. PMID:23748683

  16. [Technological advances and hospital-at-home care].

    PubMed

    Tibaldi, Vittoria; Aimonino Ricauda, Nicoletta; Rocco, Maurizio; Bertone, Paola; Fanton, Giordano; Isaia, Giancarlo

    2013-05-01

    Advances in the miniaturization and portability of diagnostic technologies, information technologies, remote monitoring, and long-distance care have increased the viability of home-based care, even for patients with serious conditions. Telemedicine and teleradiology projects are active at the Hospital at Home Service of Torino.

  17. They watch and wonder. Public attitudes toward advanced technology

    NASA Technical Reports Server (NTRS)

    Laporte, T.; Metlay, D.

    1975-01-01

    The relationship of technological development to individual and community response was investigated to provide a general conceptual, as well as empirical basis, for an understanding of the impact of advanced technologies on social life. Results of the surveys are presented in tables and graphs.

  18. Advanced Radioisotope Power Conversion Technology Research and Development

    NASA Technical Reports Server (NTRS)

    Wong, Wayne A.

    2004-01-01

    NASA's Radioisotope Power Conversion Technology program is developing next generation power conversion technologies that will enable future missions that have requirements that cannot be met by either the ubiquitous photovoltaic systems or by current Radioisotope Power System (RPS) technology. Performance goals of advanced radioisotope power systems include improvement over the state-of-practice General Purpose Heat Source/Radioisotope Thermoelectric Generator by providing significantly higher efficiency to reduce the number of radioisotope fuel modules, and increase specific power (watts/kilogram). Other Advanced RPS goals include safety, long-life, reliability, scalability, multi-mission capability, resistance to radiation, and minimal interference with the scientific payload. NASA has awarded ten contracts in the technology areas of Brayton, Stirling, Thermoelectric, and Thermophotovoltaic power conversion including five development contracts that deal with more mature technologies and five research contracts. The Advanced RPS Systems Assessment Team includes members from NASA GRC, JPL, DOE and Orbital Sciences whose function is to review the technologies being developed under the ten Radioisotope Power Conversion Technology contracts and assess their relevance to NASA's future missions. Presented is an overview of the ten radioisotope power conversion technology contracts and NASA's Advanced RPS Systems Assessment Team.

  19. The role of voice technology in advanced helicopter cockpits

    NASA Technical Reports Server (NTRS)

    Harper, H. P.

    1982-01-01

    The status of voice output and voice recognition technology in relation to helicopter cockpit applications is described. The maturing of this technology provides many opportunities for new approaches to crew workload reduction. The helicopter operating environment, potential application areas, and the impact on advanced cockpit design are discussed.

  20. 78 FR 18287 - Passenger Screening Using Advanced Imaging Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... confirmed that both the backscatter and millimeter wave technologies are safe because the x-ray or radio... bottled liquid scanners, advanced technology x-ray systems, explosives trace detection (ETD) units, and...-through explosive detection portals, document scanners, shoe scanners, and backscatter x-ray...

  1. MentorLinks: Advancing Technological Education, 2008-2010

    ERIC Educational Resources Information Center

    Hause, Ellen M., Ed.

    2010-01-01

    MentorLinks, part of the Advancing Technological Education program supported by the National Science Foundation and administered by the American Association of Community Colleges (AACC), provides technical assistance and networking opportunities to improve community college programs that prepare technicians in the science, technology, engineering,…

  2. The Advanced Technology Environmental Education Center Summer Fellows Institute.

    ERIC Educational Resources Information Center

    Depken, Diane E.; Zeman, Catherine L.; Lensch, Ellen Kabat; Brown, Edward J.

    2002-01-01

    Describes the background, activities, and outcomes of the Advanced Technology Environmental Education Center (ATEEC) and its Summer Fellows Institutes as a model for disciplinary and cross-disciplinary infusion of environmental science and technology content, curriculum, and methods into the classroom. Presents experiences, themes, and activities…

  3. On the Horizon: New Advances in Security Technology

    ERIC Educational Resources Information Center

    Gamble, Cheryl

    2005-01-01

    The worlds of security and technology have been on an intersecting course since the first published account of the use of fingerprint identification made news in 1880 (although unpublished reports suggest its use as early as 1858). In the three and one half years since the September 11 attacks, technological advances across the security field have…

  4. New Opportunities with the Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Bauer, Robert

    1998-01-01

    Various issues associated with the Advanced Communications Technology Satellite (ACTS) are presented in viewgraph form. Specific topics include: 1) ACTS program review; 2) Spot beam locations; 3) Key ACTS technologies; 4) ACTS accomplishments; 5) Experiments operations; 6) Inclined orbit opportunity, mission and impact; 7) Modifications summary; 8) Experiment opportunity, categories, processes; and 9) Recent and ongoing activity.

  5. Advanced Catalysts for Fuel Cells

    NASA Technical Reports Server (NTRS)

    Narayanan, Sekharipuram R.; Whitacre, Jay; Valdez, T. I.

    2006-01-01

    This viewgraph presentation reviews the development of catalyst for Fuel Cells. The objectives of the project are to reduce the cost of stack components and reduce the amount of precious metal used in fuel cell construction. A rapid combinatorial screening technique based on multi-electrode thin film array has been developed and validated for identifying catalysts for oxygen reduction; focus shifted from methanol oxidation in FY05 to oxygen reduction in FY06. Multi-electrode arrays of thin film catalysts of Pt-Ni and Pt-Ni-Zr have been deposited. Pt-Ni and have been characterized electrochemically and structurally. Pt-Ni-Zr and Pt-Ni films show higher current density and onset potential compared to Pt. Electrocatalytic activity and onset potential are found to be strong function of the lattice constant. Thin film Pt(59)Ni(39)Zr(2) can provide 10 times the current density of thin film Pt. Thin film Pt(59)Ni(39)Zr(2) also shows 65mV higher onset potential than Pt.

  6. Human factors of advanced technology (glass cockpit) transport aircraft

    NASA Technical Reports Server (NTRS)

    Wiener, Earl L.

    1989-01-01

    A three-year study of airline crews at two U.S. airlines who were flying an advanced technology aircraft, the Boeing 757 is discussed. The opinions and experiences of these pilots as they view the advanced, automated features of this aircraft, and contrast them with previous models they have flown are discussed. Training for advanced automation; (2) cockpit errors and error reduction; (3) management of cockpit workload; and (4) general attitudes toward cockpit automation are emphasized. The limitations of the air traffic control (ATC) system on the ability to utilize the advanced features of the new aircraft are discussed. In general the pilots are enthusiastic about flying an advanced technology aircraft, but they express mixed feelings about the impact of automation on workload, crew errors, and ability to manage the flight.

  7. Proceedings -- US Russian workshop on fuel cell technologies

    SciTech Connect

    Baker, B.; Sylwester, A.

    1996-04-01

    On September 26--28, 1995, Sandia National Laboratories sponsored the first Joint US/Russian Workshop on Fuel Cell Technology at the Marriott Hotel in Albuquerque, New Mexico. This workshop brought together the US and Russian fuel cell communities as represented by users, producers, R and D establishments and government agencies. Customer needs and potential markets in both countries were discussed to establish a customer focus for the workshop. Parallel technical sessions defined research needs and opportunities for collaboration to advance fuel cell technology. A desired outcome of the workshop was the formation of a Russian/American Fuel Cell Consortium to advance fuel cell technology for application in emerging markets in both countries. This consortium is envisioned to involve industry and national labs in both countries. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  8. Technological Advances--New Opportunities for Educators.

    ERIC Educational Resources Information Center

    Senese, Donald J.

    Pointing out a serious decline in the educational attainment of the nation's youth, this discussion of ways in which technology can begin to renew and improve education in American schools argues that, just as cable television and computer teleconferencing opened communication capabilities, the microcomputer presents unlimited possibilities for…

  9. Evaluation of the Advanced Subsonic Technology Program Noise Reduction Benefits

    NASA Technical Reports Server (NTRS)

    Golub, Robert A.; Rawls, John W., Jr.; Russell, James W.

    2005-01-01

    This report presents a detailed evaluation of the aircraft noise reduction technology concepts developed during the course of the NASA/FAA Advanced Subsonic Technology (AST) Noise Reduction Program. In 1992, NASA and the FAA initiated a cosponsored, multi-year program with the U.S. aircraft industry focused on achieving significant advances in aircraft noise reduction. The program achieved success through a systematic development and validation of noise reduction technology. Using the NASA Aircraft Noise Prediction Program, the noise reduction benefit of the technologies that reached a NASA technology readiness level of 5 or 6 were applied to each of four classes of aircraft which included a large four engine aircraft, a large twin engine aircraft, a small twin engine aircraft and a business jet. Total aircraft noise reductions resulting from the implementation of the appropriate technologies for each class of aircraft are presented and compared to the AST program goals.

  10. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  11. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at the NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  12. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art (SOA) instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  13. Technological advances in extracorporeal membrane oxygenation for respiratory failure.

    PubMed

    Rehder, Kyle J; Turner, David A; Bonadonna, Desiree; Walczak, Richard J; Rudder, Robert J; Cheifetz, Ira M

    2012-08-01

    Extracorporeal membrane oxygenation (ECMO) for neonatal and pediatric cardiac and/or respiratory failure is well established, and its use for adult respiratory failure is rapidly increasing. Management strategies developed over the past 30 years coupled with significant recent technological advances have led to improved ECMO survival. These new technologies are expanding the potential applications for ECMO in exciting ways, including new patient populations and the ability to make ECMO mobile for both intra- and inter-hospital transport. In this article, we highlight some of the recent technological advances and their impact on the utilization of ECMO in increasingly diverse patient populations.

  14. Advanced helmet tracking technology developments for naval aviation

    NASA Astrophysics Data System (ADS)

    Brindle, James H.

    1996-06-01

    There is a critical need across the Services to improve the effectiveness of aircrew within the crewstation by capitalizing on the natural psycho-motor skills of the pilot through the use of a variety of helmet-mounted visual display and control techniques. This has resulted in considerable interest and significant ongoing research and development efforts on the part of the Navy, as well as the Army and the Air Force, in the technology building blocks associated with this area, such as advanced head position sensing or head tracking technologies, helmet- mounted display optics and electronics, and advanced night vision or image intensification technologies.

  15. Comparative values of advanced space solar cells

    NASA Technical Reports Server (NTRS)

    Slifer, L. W., Jr.

    1982-01-01

    A methodology for deriving a first order dollar value estimate for advanced solar cells which consists of defining scenarios for solar array production and launch to orbit and the associated costs for typical spacecraft, determining that portion affected by cell design and performance and determining the attributable cost differences is presented. Break even values are calculated for a variety of cells; confirming that efficiency and related effects of radiation resistance and temperature coefficient are major factors; array tare mass, packaging and packing factor are important; but cell mass is of lesser significance. Associated dollar values provide a means of comparison.

  16. "ATLAS" Advanced Technology Life-cycle Analysis System

    NASA Technical Reports Server (NTRS)

    Lollar, Louis F.; Mankins, John C.; ONeil, Daniel A.

    2004-01-01

    Making good decisions concerning research and development portfolios-and concerning the best systems concepts to pursue - as early as possible in the life cycle of advanced technologies is a key goal of R&D management This goal depends upon the effective integration of information from a wide variety of sources as well as focused, high-level analyses intended to inform such decisions Life-cycle Analysis System (ATLAS) methodology and tool kit. ATLAS encompasses a wide range of methods and tools. A key foundation for ATLAS is the NASA-created Technology Readiness. The toolkit is largely spreadsheet based (as of August 2003). This product is being funded by the Human and Robotics The presentation provides a summary of the Advanced Technology Level (TRL) systems Technology Program Office, Office of Exploration Systems, NASA Headquarters, Washington D.C. and is being integrated by Dan O Neil of the Advanced Projects Office, NASA/MSFC, Huntsville, AL

  17. Economic impact of applying advanced technologies to transport airplanes.

    NASA Technical Reports Server (NTRS)

    Carline, A. J. K.

    1972-01-01

    Various technologies have been studied which could have application to the design of future transport airplanes. These technologies include the use of supercritical aerodynamics, composite materials, and active control systems, together with advanced engine designs that provide lower noise and pollutant levels. The economic impact of each technology is shown for a typical fleet of 195-passenger, transcontinental commercial transports cruising at both 0.9M and 0.98M. Comparisons are made with conventional transports cruising at 0.82M. Effects of combining the technologies are discussed. An R & D program aimed at bringing the technologies to fruition is outlined.

  18. Advanced technology for reducing aircraft engine pollution

    NASA Technical Reports Server (NTRS)

    Jones, R. E.

    1973-01-01

    Combustor research programs are described whose purpose is to demonstrate significantly lower exhaust emission levels. The proposed EPA regulations covering the allowable levels of emissions will require a major technological effort if these levels are to be met by 1979. Pollution reduction technology is being pursued by NASA through a combination of in-house research, contracted progams, and university grants. In-house research with the swirl-can modular combustor and the double-annular combustor has demonstrated significant reduction in the level of NO(x) emissions. The work is continuing in an attempt to further reduce these levels by improvements in module design and in air-fuel scheduling. Research on the reduction of idle emissions has included the conversion of conventional duplex fuel nozzles to air-assisted nozzles and exploration of the potential improvements possible with fuel staging and variable combustor geometry.

  19. Advanced protection technology for ground combat vehicles.

    PubMed

    Bosse, Timothy G

    2012-01-01

    Just as highway drivers use radar detectors to attempt to stay ahead of police armed with the latest radar technology, the Armed Forces are locked in a spiral to protect combat vehicles and their crews against the latest threats in both the contemporary operating environment and the anticipated operating environment (ie, beyond 2020). In response to bigger, heavier, or better-protected vehicles, adversaries build and deploy larger explosive devices or bombs. However, making improvements to combat vehicles is much more expensive than deploying larger explosives. In addition, demand is increasing for lighter-weight vehicles capable of rapid deployment. Together, these two facts give the threat a clear advantage in the future. To protect vehicles and crews, technologies focusing on detection and hit avoidance, denial of penetration, and crew survivability must be combined synergistically to provide the best chance of survival on the modern battlefield. PMID:22865132

  20. Advanced Optical Technologies for Space Exploration

    NASA Technical Reports Server (NTRS)

    Clark, Natalie

    2007-01-01

    NASA Langley Research Center is involved in the development of photonic devices and systems for space exploration missions. Photonic technologies of particular interest are those that can be utilized for in-space communication, remote sensing, guidance navigation and control, lunar descent and landing, and rendezvous and docking. NASA Langley has recently established a class-100 clean-room which serves as a Photonics Fabrication Facility for development of prototype optoelectronic devices for aerospace applications. In this paper we discuss our design, fabrication, and testing of novel active pixels, deformable mirrors, and liquid crystal spatial light modulators. Successful implementation of these intelligent optical devices and systems in space, requires careful consideration of temperature and space radiation effects in inorganic and electronic materials. Applications including high bandwidth inertial reference units, lightweight, high precision star trackers for guidance, navigation, and control, deformable mirrors, wavefront sensing, and beam steering technologies are discussed. In addition, experimental results are presented which characterize their performance in space exploration systems.

  1. Recent advances in offshore pipeline technology

    SciTech Connect

    Bruschi, R.; Vitali, L.

    1994-12-31

    Since the pioneering construction of the TRANSMED pipeline system across the Sicily Channel in the early 80`s, offshore pipeline technology has been progressing towards more and more difficult environments. Now the projects envisaged for the 90`s are venturing far beyond the challenges of the recent past. The scope of this paper is to present the recent research efforts aimed at tackling the main design aspects of the new challenges. Particular attention will be given to the experiences and achievements on the last few years in transmission pipelines across the European Continental Shelf, e.g. in the Central and Southern North Sea and across the Mediterranean Sea. Technologies, tools and purpose developed criteria will be discussed. The performance of current operating pipeline systems will be reviewed and incentives to rationalize design criteria and guidelines will be illustrated.

  2. Recent advances in magnetic heat pump technology

    NASA Astrophysics Data System (ADS)

    Uherka, Kenneth L.; Hull, John R.; Scheihing, Paul E.

    Magnetic heat pump (MHP)/refrigeration systems, incorporating state-of-the-art superconducting magnet technology, were assessed for industrial applications ranging from the liquefaction of gases (20 K to 100 K range) to cold storage refrigeration for food preservation (250 K to 320 K range). Initial market penetration of MHP technology is anticipated to occur in the gas liquefaction sector, since the performance advantages of magnetic refrigeration cycles relative to gas compression cycles and other conventional systems are more pronounced in the lower temperature ranges. Design options for rotary MHP devices include alternative regeneration schemes to obtain the temperature spans necessary for industrial applications. The results of preliminary design assessment studies indicate that active magnetic regenerator concepts, in which the magnetic working material also serves as the regenerative medium, offer advantages over alternative MHP designs for industrial applications.

  3. Ethical aspects of advanced reproductive technologies.

    PubMed

    Schenker, Joseph G

    2003-11-01

    The progress achieved during the last 25 years in the assisted reproductive technology field has been phenomenal. Many countries currently practice genetic material donation, human embryo cryopreservation, selective embryo reduction, preimplantation genetic diagnosis, and surrogacy. While embryo research and therapeutic cloning are carried out only in a few centers, thus far human cloning has been universally condemned. Nonetheless, the rapid evolution and progress of these various techniques of assisted reproduction has opened a Pandora's box of ethical issues that must be urgently addressed.

  4. Advanced Turbine Technology Applications Project (ATTAP)

    NASA Technical Reports Server (NTRS)

    1991-01-01

    ATTAP activities were highlighted by test bed engine design and development activities; ceramic component design; materials and engine component characterization; ceramic component process development and fabrication; component rig testing; and test bed engine fabrication and testing. Specifically, ATTAP aims to develop and demonstrate the technology of structural ceramics that have the potential for competitive automotive engine life cycle cost and for operating for 3500 hours in a turbine engine environment at temperatures up to 1371 C (2500 F).

  5. Advances in analytical technologies for environmental protection and public safety.

    PubMed

    Sadik, O A; Wanekaya, A K; Andreescu, S

    2004-06-01

    Due to the increased threats of chemical and biological agents of injury by terrorist organizations, a significant effort is underway to develop tools that can be used to detect and effectively combat chemical and biochemical toxins. In addition to the right mix of policies and training of medical personnel on how to recognize symptoms of biochemical warfare agents, the major success in combating terrorism still lies in the prevention, early detection and the efficient and timely response using reliable analytical technologies and powerful therapies for minimizing the effects in the event of an attack. The public and regulatory agencies expect reliable methodologies and devices for public security. Today's systems are too bulky or slow to meet the "detect-to-warn" needs for first responders such as soldiers and medical personnel. This paper presents the challenges in monitoring technologies for warfare agents and other toxins. It provides an overview of how advances in environmental analytical methodologies could be adapted to design reliable sensors for public safety and environmental surveillance. The paths to designing sensors that meet the needs of today's measurement challenges are analyzed using examples of novel sensors, autonomous cell-based toxicity monitoring, 'Lab-on-a-Chip' devices and conventional environmental analytical techniques. Finally, in order to ensure that the public and legal authorities are provided with quality data to make informed decisions, guidelines are provided for assessing data quality and quality assurance using the United States Environmental Protection Agency (US-EPA) methodologies. PMID:15173903

  6. Science and society: a stem cell technology model.

    PubMed

    Kiatpongsan, Sorapop

    2008-02-01

    Stem cell technology has been recognized as an emerging technology that could transform current supportive approach toward curing many chronic disorders and degenerative conditions. Regenerative medicine is the promising area of medical practice in the coming decade. However, stem cell technology also brings up controversial issues from the bioethical perspective such as the destruction of human embryos to derive embryonic stem cells or putting the egg donors at risk when retrieving oocytes used in somatic cell nuclear transfer technique. Recently, scientists have discovered a novel method to derive human embryonic stem cell-like cells (iPS; induced pluripotent stem cells) from human skin cells. This innovative approach would not only be a breakthrough discovery to advance the knowledge of stem cell research and the landmark for future stem cell-based therapy but will also provide viable solutions for social concerns on bioethical issues.

  7. Advancements in the micromirror array projector technology

    NASA Astrophysics Data System (ADS)

    Beasley, David B.; Bender, Matt W.; Crosby, Jay; Messer, Tim; Saylor, Daniel A.

    2003-09-01

    The Micromirror Array Projector System (MAPS) is a state-of-the-art dynamic scene projector developed by Optical Sciences Corporation (OSC) for Hardware-In-the-Loop (HWIL) simulation and sensor test applications. Since the introduction of the first MAPS in 2001, OSC has continued to improve the technology and develop systems for new projection and test applications. The MAPS is based upon the Texas Instruments Digital Micromirror Device (DMD) which has been modified to project high resolution, realistic imagery suitable for testing sensors and seekers operating in the UV, visible, NIR, and IR wavebands. This paper reviews the basic design and describes recent developments and new applications of the MAPS technology. Recent developments for the MAPS include increasing the format of the micromirror array to 1024x768 and increasing the binary frame rate to 10KHz. The MAPS technology has also been applied to the design of a Mobile Extended Spectrum Electro-Optical Test Set (MESEOTS). This test set is designed for testing UV, visible, NIR and IR sensors as well as laser rangefinders, laser trackers, and laser designators. The design and performance of the improved MAPS and the MESEOTS are discussed in paper.

  8. Commercial development of advanced PFBC technology

    SciTech Connect

    McClung, J.D.

    1995-12-31

    In the 1970s, the coal-fired power generation industry recognized that the declining price of electricity over the previous five decades was coming to an end. Maximum use had been made of existing cycle efficiencies and scale-up. As researchers looked for a new approach, the focus shifted from the fully developed Rankine cycle to a new array of coal-fired plants using combined-cycle technology. Now, coal-fired combined-cycle plants are being introduced that shift power production to the Brayton cycle. Integrated Gasification Combined Cycle (IGCC) and Pressurized Fluidized Bed Combustion (PFBC) are two technologies at the forefront of this approach. The PFBC approach burns coal in a fluidized bed combustor at elevated pressure. The plant generates electricity from a gas turbine (expanding the hot, pressurized products of combustion) in addition to the conventional steam (bottoming) cycle. Such a plant can achieve thermal efficiencies of about 40 percent and have a levelized busbar cost below any competing coal-based technology. In addition to the economic benefits, the {open_quotes}built-in{close_quotes} feature of environmental control (SO{sub 2} and NO{sub x}) in the combustion process eliminates the need for external gas cleanup such as scrubbers. A PFBC can burn a wider range of coals than a pulverized-coal-fired (PCF) boiler and is simpler to operate and maintain than an IGCC power plant.

  9. Technological advances in high-throughput screening.

    PubMed

    Liu, Bailing; Li, Songjun; Hu, Jie

    2004-01-01

    High-throughput screening (HTS) is the process of testing a large number of diverse chemical structures against disease targets to identify 'hits'. Compared to traditional drug screening methods, HTS is characterized by its simplicity, rapidness, low cost, and high efficiency, taking the ligand-target interactions as the principle, as well as leading to a higher information harvest. As a multidisciplinary field, HTS involves an automated operation-platform, highly sensitive testing system, specific screening model (in vitro), an abundant components library, and a data acquisition and processing system. Various technologies, especially the novel technologies such as fluorescence, nuclear-magnetic resonance, affinity chromatography, surface plasmon resonance, and DNA microarray, are now available, and the screening of more than 100,000 samples per day is already possible. Fluorescence-based assays include the scintillation proximity assay, time-resolved energy transfer, fluorescence anisotropy, fluorescence correlation spectroscopy, and fluorescence fluctuation spectroscopy. Fluorescence-based techniques are likely to be among the most important detection approaches used for HTS due to their high sensitivity and amenability to automation, giving the industry-wide drive to simplify, miniaturize, and speed up assays. The application of NMR technology to HTS is another recent trend in drug research. One advantage afforded by NMR technology is that it can provide direct information on the affinity of the screening compounds and the binding location of protein. The structure-activity relationship acquired from NMR analysis can sharpen the library design, which will be very important in furnishing HTS with well-defined drug candidates. Affinity chromatography used for library screening will provide the information on the fundamental processes of drug action, such as absorption, distribution, excretion, and receptor activation; also the eluting curve can give directly the

  10. Advanced lost foam from casting technology

    SciTech Connect

    Bates, C. E.; Littleton, H. E.; Askeland, D.; Griffin, J.; Miller, B. A.; Sheldon, D. S.

    1996-05-01

    Previous research made significant advances in understanding the Lost Foam Casting (LFC) Process and clearly identified areas where additional research was needed to improve the process and make it more functional in an industrial environment. The current project focused on five areas listed as follows: Task 1: Precision Pattern Production Task 2: Pattern Coating Consistency Task 3: Sand Fill and Compaction Effects Task 4: Pattern Gating Task 5: Mechanical Properties of Castings. This report summarizes the work done under the current contract in all five areas in the period of October 1, 1994 through December 31, 1995. Twenty-eight (28) companies jointly participate in the project. These companies represent a variety of disciplines, including pattern designers, pattern producers, coating manufacturers, plant design companies, compaction equipment manufacturers, casting producers, and casting buyers.

  11. Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells

    PubMed Central

    Patel, Minal; Yang, Shuying

    2010-01-01

    Traditionally, nuclear reprogramming of cells has been performed by transferring somatic cell nuclei into oocytes, by combining somatic and pluripotent cells together through cell fusion and through genetic integration of factors through somatic cell chromatin. All of these techniques changes gene expression which further leads to a change in cell fate. Here we discuss recent advances in generating induced pluripotent stem cells, different reprogramming methods and clinical applications of iPS cells. Viral vectors have been used to transfer transcription factors (Oct4, Sox2, c-myc, Klf4, and nanog) to induce reprogramming of mouse fibroblasts, neural stem cells, neural progenitor cells, keratinocytes, B lymphocytes and meningeal membrane cells towards pluripotency. Human fibroblasts, neural cells, blood and keratinocytes have also been reprogrammed towards pluripotency. In this review we have discussed the use of viral vectors for reprogramming both animal and human stem cells. Currently, many studies are also involved in finding alternatives to using viral vectors carrying transcription factors for reprogramming cells. These include using plasmid transfection, piggyback transposon system and piggyback transposon system combined with a non viral vector system. Applications of these techniques have been discussed in detail including its advantages and disadvantages. Finally, current clinical applications of induced pluripotent stem cells and its limitations have also been reviewed. Thus, this review is a summary of current research advances in reprogramming cells into induced pluripotent stem cells. PMID:20336395

  12. Application of advanced technologies to small, short-haul aircraft

    NASA Technical Reports Server (NTRS)

    Andrews, D. G.; Brubaker, P. W.; Bryant, S. L.; Clay, C. W.; Giridharadas, B.; Hamamoto, M.; Kelly, T. J.; Proctor, D. K.; Myron, C. E.; Sullivan, R. L.

    1978-01-01

    The results of a preliminary design study which investigates the use of selected advanced technologies to achieve low cost design for small (50-passenger), short haul (50 to 1000 mile) transports are reported. The largest single item in the cost of manufacturing an airplane of this type is labor. A careful examination of advanced technology to airframe structure was performed since one of the most labor-intensive parts of the airplane is structures. Also, preliminary investigation of advanced aerodynamics flight controls, ride control and gust load alleviation systems, aircraft systems and turbo-prop propulsion systems was performed. The most beneficial advanced technology examined was bonded aluminum primary structure. The use of this structure in large wing panels and body sections resulted in a greatly reduced number of parts and fasteners and therefore, labor hours. The resultant cost of assembled airplane structure was reduced by 40% and the total airplane manufacturing cost by 16% - a major cost reduction. With further development, test verification and optimization appreciable weight saving is also achievable. Other advanced technology items which showed significant gains are as follows: (1) advanced turboprop-reduced block fuel by 15.30% depending on range; (2) configuration revisions (vee-tail)-empennage cost reduction of 25%; (3) leading-edge flap addition-weight reduction of 2500 pounds.

  13. Advances in cell culture: anchorage dependence

    PubMed Central

    Merten, Otto-Wilhelm

    2015-01-01

    Anchorage-dependent cells are of great interest for various biotechnological applications. (i) They represent a formidable production means of viruses for vaccination purposes at very large scales (in 1000–6000 l reactors) using microcarriers, and in the last decade many more novel viral vaccines have been developed using this production technology. (ii) With the advent of stem cells and their use/potential use in clinics for cell therapy and regenerative medicine purposes, the development of novel culture devices and technologies for adherent cells has accelerated greatly with a view to the large-scale expansion of these cells. Presently, the really scalable systems—microcarrier/microcarrier-clump cultures using stirred-tank reactors—for the expansion of stem cells are still in their infancy. Only laboratory scale reactors of maximally 2.5 l working volume have been evaluated because thorough knowledge and basic understanding of critical issues with respect to cell expansion while retaining pluripotency and differentiation potential, and the impact of the culture environment on stem cell fate, etc., are still lacking and require further studies. This article gives an overview on critical issues common to all cell culture systems for adherent cells as well as specifics for different types of stem cells in view of small- and large-scale cell expansion and production processes. PMID:25533097

  14. Single-cell technologies to study the immune system.

    PubMed

    Proserpio, Valentina; Mahata, Bidesh

    2016-02-01

    The immune system is composed of a variety of cells that act in a coordinated fashion to protect the organism against a multitude of different pathogens. The great variability of existing pathogens corresponds to a similar high heterogeneity of the immune cells. The study of individual immune cells, the fundamental unit of immunity, has recently transformed from a qualitative microscopic imaging to a nearly complete quantitative transcriptomic analysis. This shift has been driven by the rapid development of multiple single-cell technologies. These new advances are expected to boost the detection of less frequent cell types and transient or intermediate cell states. They will highlight the individuality of each single cell and greatly expand the resolution of current available classifications and differentiation trajectories. In this review we discuss the recent advancement and application of single-cell technologies, their limitations and future applications to study the immune system.

  15. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    SciTech Connect

    2010-01-01

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  16. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    ScienceCinema

    None

    2016-07-12

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  17. Commercialization of Australian advanced infrared technology

    NASA Astrophysics Data System (ADS)

    Redpath, John; Brown, Allen; Woods, William F.

    1995-09-01

    For several decades, the main thrust in infrared technology developments in Australia has been in two main sensor technologies: uncooled silicon chip printed bolometric sensors pioneered by DSTO's Kevin Liddiard, and precision engineered high quality Cadmium Mercury Telluride developed at DSTO under the guidance of Dr. Richard Hartley. In late 1993 a low cost infrared imaging device was developed at DSTO as a sensor for guided missiles. The combination of these three innovations made up a unique package that enabled Australian industry to break through the barriers of commercializing infrared technology. The privately owned company, R.J. Optronics Pty Ltd undertook the process of re-engineering a selection of these DSTO developments to be applicable to a wide range of infrared products. The first project was a novel infrared imager based on a Palmer scan (translated circle) mechanism. This device applies a spinning wedge and a single detector, it uses a video processor to convert the image into a standard rectangular format. Originally developed as an imaging seeker for a stand-off weapon, it is producing such high quality images at such a low cost that it is now also being adapted for a wide variety of other military and commercial applications. A technique for electronically stabilizing it has been developed which uses the inertial signals from co-mounted sensors to compensate for platform motions. This enables it to meet the requirements of aircraft, marine vessels and masthead sight applications without the use of gimbals. After tests on a three-axis motion table, several system configurations have now been successfully operated on a number of lightweight platforms, including a Cessna 172 and the Australian made Seabird Seeker aircraft.

  18. Advanced technologies for rocket single-stage-to-orbit vehicles

    NASA Astrophysics Data System (ADS)

    Wilhite, Alan W.; Bush, Lance B.; Cruz, Christopher I.; Lepsch, Roger A.; Morris, W. Douglas; Stanley, Douglas O.; Wurster, Kathryn E.

    1991-01-01

    A single-stage-to-orbit vertical takeoff/horizontal landing rocket vehicle was studied to determine the benefits of advanced technology. Advanced technologies that were included in the study were variable mixture ratio oxygen/hydrogen rocket engines and materials, structures, and subsystem technologies currently being developed in the National Aero-Space Plane Program. The application of advanced technology results in an 85 percent reduction in vehicle dry weight. With advanced materials, an external thermal protection system, like the Space Shuttle tiles, was not required. Compared to an all-airbreathing horizontal takeoff/horizontal landing vehicle using the same advanced technologies and mission requirements, the rocket vehicle is lighter in dry weight and has fewer subsystems. To increase reliability and safety, operational features were included in the rocket vehicle-robust subsystems, 5 percent additional margin, no slush hydrogen, fail-operational with an engine out, and a crew escape module. The resulting vehicle grew in dry weight and was still lower in dry weight than the airbreathing vehicle.

  19. Advances in air-stripper technology

    SciTech Connect

    Wilson, J.H.; Singh, S.P. ); Lucero, A.J.; Thomas, C.O. . Dept. of Chemical Engineering); Ashworth, R.A.; Elliott, M.G. ); Counce, R.M. Tennessee Univ., Knoxville, TN . Dept. of Chemical Engineering)

    1990-01-01

    The cost for application of air-stripping technology for removal of volatile organic compounds (VOC's) from groundwater has been shown to be relatively insensitive to the cost of the installed capital equipment. In light of this observation, the basis for selection of air stripping equipment may include site-specific requirements without major economic penalties. In this paper, potential advantages for the use of highly efficient packings for traditional packed towers and a commercial rotary gas-liquid contactor are pointed out, and a basis for design is provided. 11 refs., 10 figs.

  20. Networking Technologies Enable Advances in Earth Science

    NASA Technical Reports Server (NTRS)

    Johnson, Marjory; Freeman, Kenneth; Gilstrap, Raymond; Beck, Richard

    2004-01-01

    This paper describes an experiment to prototype a new way of conducting science by applying networking and distributed computing technologies to an Earth Science application. A combination of satellite, wireless, and terrestrial networking provided geologists at a remote field site with interactive access to supercomputer facilities at two NASA centers, thus enabling them to validate and calibrate remotely sensed geological data in near-real time. This represents a fundamental shift in the way that Earth scientists analyze remotely sensed data. In this paper we describe the experiment and the network infrastructure that enabled it, analyze the data flow during the experiment, and discuss the scientific impact of the results.

  1. Advanced energy systems and technologies research programme

    NASA Astrophysics Data System (ADS)

    Lund, P.; Tuominen, E.

    NEMO 2 is a national energy research program for the evaluation, development and promotion of new and renewable forms of energy. NEMO 2 is one of the energy research programs of the Finnish Ministry of Trade and Industry for the years 1993-1998. In NEMO 2 -program, new energy technology is developed as a whole in close collaboration between industry, universities and research institutes, as well as with customers and consumers. The overall budget of NEMO 2 is close to 125 MFIM (1 dollar = 5.7 FIM, Nov. 1993). The main emphasis of the program is on wind and solar energy.

  2. Advances in Detector Technology for Infrared Astronomy

    NASA Technical Reports Server (NTRS)

    McCreight, Craig; Cheng, P. L. (Technical Monitor)

    1995-01-01

    Progress in semiconductor materials and processing technology has allowed the development of infrared detector arrays with unprecedented sensitivity, for imaging and spectroscopic applications in astronomy. The earlier discrete-detector approach has been replaced by large-element (up to 1024 x 1024 pixel), multiplexed devices. Progress has been made against a number of key limiting factors, such as quantum efficiency, noise, spectral response, linearity, and dark current. Future developments will focus on the need for even larger arrays, which operate at higher temperatures.

  3. Recent advances and future applications of microfluidic live-cell microarrays.

    PubMed

    Rothbauer, Mario; Wartmann, David; Charwat, Verena; Ertl, Peter

    2015-11-01

    Microfluidic live-cell microarrays show much promise as screening tools for biomedical research because they could shed light on key biological processes such as cell signaling and cell-to-cell and cell-to-substrate dynamic responses. While miniaturization reduces the need for expensive clinical grade reagents, the integration of functional components including micropumps, biosensors, actuators, mixers and gradient generators results in improved assay reliability, reproducibility and well-defined cell culture conditions. The present review addresses recent technological advances in microfluidic live-cell microarray technology with a special focus on the applications of microfluidic single-cell, multi-cell and 3D cell microarrays.

  4. [Technology development as social process: prospects and frontiers of social scientific elucidation of technological advancement].

    PubMed

    Dierkes, M

    1990-05-01

    This article provides an overview of the new developments in social scientific technology research which have changed considerably as a result of public debate and reactions to the importance of advancements in technology. The shift in emphasis, away from the effects of technology to its shaping, is described and certain hypotheses and concepts of advancement in the study of the social conditions underlying technical development processes are presented.

  5. Technology requirements for advanced earth-orbital transportation systems

    NASA Technical Reports Server (NTRS)

    Haefeli, R. C.; Littler, E. G.; Hurley, J. B.; Winter, M. G.

    1977-01-01

    Areas of advanced technology that are either critical or offer significant benefits to the development of future Earth-orbit transportation systems were identified. Technology assessment was based on the application of these technologies to fully reusable, single-stage-to-orbit (SSTO) vehicle concepts with horizontal landing capability. Study guidelines included mission requirements similar to space shuttle, an operational capability begining in 1995, and main propulsion to be advanced hydrogen-fueled rocket engines. Also evaluated was the technical and economic feasibility of this class of SSTO concepts and the comparative features of three operational take-off modes, which were vertical boost, horizontal sled launch, and horizontal take-off with subsequent inflight fueling. Projections of both normal and accelerated technology growth were made. Figures of merit were derived to provide relative rankings of technology areas. The influence of selected accelerated areas on vehicle design and program costs was analyzed by developing near-optimum point designs.

  6. Energy and Economic Trade Offs for Advanced Technology Subsonic Aircraft

    NASA Technical Reports Server (NTRS)

    Maddalon, D. V.; Wagner, R. D.

    1976-01-01

    Changes in future aircraft technology which conserve energy are studied, along with the effect of these changes on economic performance. Among the new technologies considered are laminar-flow control, composite materials with and without laminar-flow control, and advanced airfoils. Aircraft design features studied include high-aspect-ratio wings, thickness ratio, and range. Engine technology is held constant at the JT9D level. It is concluded that wing aspect ratios of future aircraft are likely to significantly increase as a result of new technology and the push of higher fuel prices. Composite materials may raise aspect radio to about 11 to 12 and practical laminar flow-control systems may further increase aspect ratio to 14 or more. Advanced technology provides significant reductions in aircraft take-off gross weight, energy consumption, and direct operating cost.

  7. Advanced metal-membrane technology-commercialization

    SciTech Connect

    Edlund, D.J.

    1995-06-01

    The gasification of coal offers a potentially significant source of hydrogen for use in clean power generation and as a primary chemical feedstock. However, hydrogen derived from coal continues to be more expensive than hydrogen derived from natural gas or petroleum, due in large part to the expense of separating hydrogen from the mixture of gases produced during gasification. At Bend Research, we have been developing a novel hydrogen-permeable metal membrane that promises to be economical for hydrogen separation and purification, including the purification of hydrogen derived from gasifying coal. Furthermore, the membrane is ideally suited for use at high temperatures (200{degrees} to 500{degrees}C), making it feasible to produce pure hydrogen directly from hot gas streams. Through a partnership with Teledyne Wah Chang, we are proceeding with scale-up of prototype membrane modules and field tests to demonstrate the technology to potential users. Additionally, we are working with potential customers to estimate capital savings and operating costs for integrated systems. In this paper, we present some of the operating characteristics of the metal membrane, including its use to drive equilibrium-limited reactions toward complete conversion (e.g., the water-gas-shift reaction). We also describe our activities for commercializing this technology for a variety of applications.

  8. Advanced ash management technologies for CFBC ash.

    PubMed

    Anthony, E J; Berry, E E; Blondin, J; Bulewicz, E M; Burwell, S

    2003-01-01

    The combustion of high-sulphur coal demands the reduction of sulphur emissions. The sorbent most often used in sulphur capture technology is calcium-based. Ashes from technologies such as circulating fluidized bed combustion (CFBC), therefore, contain high calcium levels. The use and disposal of these ashes poses challenges, because of highly exothermic reactions with water, high-pH leachates, and excessive expansion of solidified materials. This paper looks at the potential of two post-combustion ash treatment processes, CERCHAR hydration and AWDS disposal, in solving these challenges. A high-sulphur coal-derived CFBC ash is examined, after CERCHAR hydration treatment, in conjunction with a conventionally hydrated ash, in a range of chemical, geotechnical and utilization scenarios. The ashes are used to make no-cement and roller-compacted concrete as well as Ash Water Dense Suspensions (AWDS). The solidified mortar paste from no-cement concrete is subjected to an extensive geochemical examination to determine how solidification progresses and strength develops, from a chemical point of view. PMID:12909091

  9. Advanced ash management technologies for CFBC ash.

    PubMed

    Anthony, E J; Berry, E E; Blondin, J; Bulewicz, E M; Burwell, S

    2003-01-01

    The combustion of high-sulphur coal demands the reduction of sulphur emissions. The sorbent most often used in sulphur capture technology is calcium-based. Ashes from technologies such as circulating fluidized bed combustion (CFBC), therefore, contain high calcium levels. The use and disposal of these ashes poses challenges, because of highly exothermic reactions with water, high-pH leachates, and excessive expansion of solidified materials. This paper looks at the potential of two post-combustion ash treatment processes, CERCHAR hydration and AWDS disposal, in solving these challenges. A high-sulphur coal-derived CFBC ash is examined, after CERCHAR hydration treatment, in conjunction with a conventionally hydrated ash, in a range of chemical, geotechnical and utilization scenarios. The ashes are used to make no-cement and roller-compacted concrete as well as Ash Water Dense Suspensions (AWDS). The solidified mortar paste from no-cement concrete is subjected to an extensive geochemical examination to determine how solidification progresses and strength develops, from a chemical point of view.

  10. Advanced evaporator technology progress report FY 1992

    SciTech Connect

    Chamberlain, D.; Hutter, J.C.; Leonard, R.A.

    1995-01-01

    This report summarizes the work that was completed in FY 1992 on the program {open_quotes}Technology Development for Concentrating Process Streams.{close_quotes} The purpose of this program is to evaluate and develop evaporator technology for concentrating radioactive waste and product streams such as those generated by the TRUEX process. Concentrating these streams and minimizing the volume of waste generated can significantly reduce disposal costs; however, equipment to concentrate the streams and recycle the decontaminated condensates must be installed. LICON, Inc., is developing an evaporator that shows a great deal of potential for this application. In this report, concepts that need to be incorporated into the design of an evaporator operated in a radioactive environment are discussed. These concepts include criticality safety, remote operation and maintenance, and materials of construction. Both solubility and vapor-liquid equilibrium data are needed to design an effective process for concentrating process streams. Therefore, literature surveys were completed and are summarized in this report. A model that is being developed to predict vapor phase compositions is described. A laboratory-scale evaporator was purchased and installed to study the evaporation process and to collect additional data. This unit is described in detail. Two new LICON evaporators are being designed for installation at Argonne-East in FY 1993 to process low-level radioactive waste generated throughout the laboratory. They will also provide operating data from a full-sized evaporator processing radioactive solutions. Details on these evaporators are included in this report.

  11. Brazil advances subsea technology in Marlim pilot

    SciTech Connect

    Not Available

    1993-03-29

    Petroleum Brasileiro SA has extended several water depth records for subsea technology during a pilot project in giant Marlim oil field in the Campos basin off Brazil. Petrobras finished the 10 well Marlim pilot last December. The field's pilot phase was intended to begin early production and enable Petrobras to gather more reservoir data. Ten satellite wells, including two prepilot wells, were completed during the Marlim pilot phase with guidelineless (GLL) wet christmas trees designed and fabricated by FMC Corp., Houston, and CBV Industrial Mechanic SA, Rio de Janeiro. The subsea wells are producing 52,000 b/d of oil and 21.19 MMCfd of gas in water depths of 1,847-2,562 ft. Marlim pilot well flow is routed to a permanent semisubmersible floating production system (FPS). Oil moves from the FPS to a monobuoy that offloads to a shuttle tanker. In addition to marking the first successful uses of purpose-built GLL wet trees, FMC said the Marlim pilot project allowed GLL subsea technology to evolve from conceptual status into a proven deepwater completion method. The paper describes the project.

  12. Advanced Metal and Ceramics for Clean Energy Technologies

    NASA Astrophysics Data System (ADS)

    Tanaka, Yasuzo

    In line with the Kyoto Protocol, an effective development for the clean energy technologies and related materials is very significant. Especially, an importance of metal and ceramics using the fuel cell, the solar cell and the rechargeable battery for renewable electricity generation, efficient energy conversion and energy storage technologies is much talked about.

  13. Advanced oxidation technologies for chemical demilitarization

    SciTech Connect

    Rosocha, L.A.; Korzekwa, R.A.; Monagle, M.; Coogan, J.J.; Tennant, R.A.; Brown, L.F.; Currier, R.P.

    1996-12-31

    This is the final report of a one-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory. The main project objective was to establish a technical basis for future program development in the area of chemical warfare agent destruction using a Los Alamos-developed advanced oxidation process: a two-stage device consisting of thermal packed-bed reactor (PBR) and a nonthermal plasma (NTP) reactor. Various compounds were evaluated as potential surrogates for chemical warfare (CW) agents. Representative effluent mass balances were projected for future comparisons with incinerators. The design and construction of lab-scale PBR/NTP reactors (consisting of a liquid injection and metering system, electric furnace, condensers, chemical traps, plasma reactors, power supplies, and chemical diagnostics) has been completed. This equipment, the experience gained from chemical-processing experiments, process modeling, and an initial demonstration of the feasibility of closed-loop operation, have provided a technical basis for further demonstrations and program development efforts.

  14. Technology advances keeping LNG cost-competitive

    SciTech Connect

    Bellow, E.J. Jr.; Ghazal, F.P.; Silverman, A.J.; Myers, S.D.

    1997-06-02

    LNG plants, often very expensive in the past, will in the future need to cost less to build and operate and yet maintain high safety and reliability standards, both during construction and operation. Technical advancements, both in the process and in equipment scaling, manufacturing, and metallurgy, will provide much of the impetus for the improved economics. Although world energy demand is predicted to grow on average of about 2% annually over the next decade, LNG is expected to contribute an increasing portion of this growth with annual growth rates averaging about 7%. This steep growth increase will be propelled mainly by the environmentally friendlier burning characteristics of natural gas and the strong industrial growth in Asian and pacific Rim countries. While LNG is emerging as the fuel of choice for developing economies, its delivered cost to consumers will need to stay competitive with alternate energy supplies if it is to remain in front. The paper discusses LNG process development, treating process, equipment developments (man heat exchanger, compressors, drivers, and pressure vessels), and economy of scale.

  15. Major technological advances and trends in cheese.

    PubMed

    Johnson, M E; Lucey, J A

    2006-04-01

    Over the last 25 yr, cheese production in the United States has more than doubled with most of the increase due to production in the western states. Processing large volumes of milk into cheese has necessitated changes in vat size and design, reliance on computer software, and milk standardization, including use of membrane concentration of milk either at the cheese plant or on the farm. There has been increased interest in specialty cheeses including cheese made from sheep, goat, and organic milks. In addition, membrane processing of whey into various value-added components has become routine. Changes in cheese manufacturing protocols have resulted in a reduction of the manufacturing time and the necessity for consistent and reliable starter activity. Major advances in the genetics of microorganisms have not only resulted in widespread use of fermentation-produced chymosin but also in starter bacteria with improved resistance to bacteriophage infection. Genomics and proteomics have increased the likelihood of the development of nonstarter adjuncts with specific enzymatic activity. Indeed, the use of adjunct microorganisms to produce cheese with a unique flavor profile or to produce cheese with more consistent or better quality flavor has gained almost universal acceptance.

  16. Advanced NMR technology for bioscience and biotechnology

    SciTech Connect

    Hammel, P.C.; Hernandez, G.; Trewhella, J.; Unkefer, C.J.; Boumenthal, D.K.; Kennedy, M.A.; Moore, G.J.

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). NMR plays critical roles in bioscience and biotechnology in both imaging and structure determination. NMR is limited, however, by the inherent low sensitivity of the NMR experiment and the demands for spectral resolution required to study biomolecules. The authors addressed both of these issues by working on the development of NMR force microscopy for molecular imaging, and high field NMR with isotope labeling to overcome limitations in the size of biomolecules that can be studied using NMR. A novel rf coil design for NMR force microscopy was developed that increases the limits of sensitivity in magnetic resonance detection for imaging, and the authors demonstrated sub-surface spatial imaging capabilities. The authors also made advances in the miniaturization of two critical NMR force microscope components. They completed high field NMR and isotope labeling studies of a muscle protein complex which is responsible for regulating muscle contraction and is too large for study using conventional NMR approaches.

  17. Fuel cell technology for prototype logistic fuel cell mobile systems

    SciTech Connect

    Sederquist, R.A.; Garow, J.

    1995-08-01

    Under the aegis of the Advanced Research Project Agency`s family of programs to develop advanced technology for dual use applications, International Fuel Cells Corporation (IFC) is conducting a 39 month program to develop an innovative system concept for DoD Mobile Electric Power (MEP) applications. The concept is to integrate two technologies, the phosphoric acid fuel cell (PAFC) with an auto-thermal reformer (ATR), into an efficient fuel cell power plant of nominally 100-kilowatt rating which operates on logistic fuels (JP-8). The ATR fuel processor is the key to meeting requirements for MEP (including weight, volume, reliability, maintainability, efficiency, and especially operation on logistic fuels); most of the effort is devoted to ATR development. An integrated demonstration test unit culminates the program and displays the benefits of the fuel cell system, relative to the standard 100-kilowatt MEP diesel engine generator set. A successful test provides the basis for proceeding toward deployment. This paper describes the results of the first twelve months of activity during which specific program aims have remained firm.

  18. Technology development program for an advanced microsheet glass concentrator

    NASA Technical Reports Server (NTRS)

    Richter, Scott W.; Lacy, Dovie E.

    1990-01-01

    Solar Dynamic Space Power Systems are candidate electrical power generating systems for future NASA missions. One of the key components in a solar dynamic power system is the concentrator which collects the sun's energy and focuses it into a receiver. In 1985, the NASA Lewis Research Center initiated the Advanced Solar Dynamic Concentrator Program with funding from NASA's Office of Aeronautics and Space Technology (OAST). The objectives of the Advanced Concentrator Program is to develop the technology that will lead to lightweight, highly reflective, accurate, scaleable, and long lived (7 to 10 years) space solar dynamic concentrators. The Advanced Concentrator Program encompasses new and innovative concepts, fabrication techniques, materials selection, and simulated space environmental testing. The Advanced Microsheet Glass Concentrator Program, a reflector concept, that is currently being investigated both in-house and under contract is discussed.

  19. Advanced technologies in the meat industry.

    PubMed

    Longdell, G R

    1994-01-01

    New Zealand has invested heavily in the development of slaughter dressing and deboning equipment and machinery for sheep and lamb. In total some thirteen machines have been developed to date and all are now commercially available and many examples are working within New Zealand and overseas. Significant economic savings have been derived from the introduction of these machines. The Australian meat industry is funding a major programme in beef slaughter technology development. Eleven modules have been developed and at present they are being incorporated into a commercial plant at Kilcoy in Queensland, Australia. The Netherlands have a programme named Slaughterline 2000 which includes a number of pork slaughtering and processing initiations. Stunning, sticking and an automatic carcass opener are developments within this programme.

  20. Advanced assisted reproduction technologies (ART) in goats.

    PubMed

    Baldassarre, H; Karatzas, C N

    2004-07-01

    Assisted reproduction technologies (ART) are reviewed with special emphasis on goat genetic improvement programs. Estrous synchronization and artificial insemination are the most commonly used ART worldwide because of their simplicity and excellent cost/benefit, especially when proven sires are used. Multiple ovulation and embryo transfer (MOET) has not become widely used due to its unpredictability. In vitro embryo production using oocytes collected by laparoscopy from valuable donors has the potential to improve the results obtained from MOET and expand its applications (for example, using prepubertal donors). However, the costs and inefficiencies of the system might restrict its use to special situations. Finally, transgenesis and cloning are expected to have a significant impact on the future genetic improvement of livestock. However, because of low efficiencies and high costs, their present use is restricted to applications with high returns such as the production of recombinant proteins of pharmaceutical and biomedical interest.