Science.gov

Sample records for advanced detector group

  1. CCD detector development projects by the Beamline Technical Support Group at the Advanced Photon Source

    NASA Astrophysics Data System (ADS)

    Lee, John H.; Fernandez, Patricia; Madden, Tim; Molitsky, Michael; Weizeorick, John

    2007-11-01

    This paper will describe two ongoing detector projects being developed by the Beamline Technical Support Group at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The first project is the design and construction of two detectors: a single-CCD system and a two-by-two Mosaic CCD camera for Small-Angle X-ray Scattering (SAXS). Both of these systems utilize the Kodak KAF-4320E CCD coupled to fiber optic tapers, custom mechanical hardware, electronics, and software developed at ANL. The second project is a Fast-CCD (FCCD) detector being developed in a collaboration between ANL and Lawrence Berkeley National Laboratory (LBNL). This detector will use ANL-designed readout electronics and a custom LBNL-designed CCD, with 480×480 pixels and 96 outputs, giving very fast readout.

  2. CCD detector development projects by the beamline technical support group at the Advanced Photon Source.

    SciTech Connect

    Lee, J. H.; Fernandez, P.; Madden, T.; Molitsky, M.; Weizeorick, J.

    2007-11-11

    This paper will describe two ongoing detector projects being developed by the Beamline Technical Support Group at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The first project is the design and construction of two detectors: a single-CCD system and a two-by-two Mosaic CCD camera for Small-Angle X-ray Scattering (SAXS). Both of these systems utilize the Kodak KAF-4320E CCD coupled to fiber optic tapers, custom mechanical hardware, electronics, and software developed at ANL. The second project is a Fast-CCD (FCCD) detector being developed in a collaboration between ANL and Lawrence Berkeley National Laboratory (LBNL). This detector will use ANL-designed readout electronics and a custom LBNL-designed CCD, with 480 x 480 pixels and 96 outputs, giving very fast readout.

  3. Advanced far infrared detectors

    SciTech Connect

    Haller, E.E.

    1993-05-01

    Recent advances in photoconductive and bolometric semiconductor detectors for wavelength 1 mm > {lambda} > 50 {mu}m are reviewed. Progress in detector performance in this photon energy range has been stimulated by new and stringent requirements for ground based, high altitude and space-borne telescopes for astronomical and astrophysical observations. The paper consists of chapters dealing with the various types of detectors: Be and Ga doped Ge photoconductors, stressed Ge:Ga devices and neutron transmutation doped Ge thermistors. Advances in the understanding of basic detector physics and the introduction of modern semiconductor device technology have led to predictable and reliable fabrication techniques. Integration of detectors into functional arrays has become feasible and is vigorously pursued by groups worldwide.

  4. The Advanced LIGO Detectors

    NASA Astrophysics Data System (ADS)

    Fritschel, Peter

    2016-03-01

    After decades of development, the Advanced LIGO gravitational wave detectors are now operating, and they completed their first observational run in early 2016. Advanced LIGO consists of two 4-km scale interferometric detectors located at separate sites in the US. The first year of detector commissioning that led to the first observation run produced instruments that have several times better sensitivity to gravitational-wave strain than previous instruments. At their final design sensitivity, the detectors will be another factor of 2-3x more sensitive than current performance. This talk will cover the design of Advanced LIGO, explain how the sensitivity improvements have been achieved, and lay out the path to reaching final design sensitivity.

  5. Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    Blair, D. G.; Howell, E. J.; Ju, L.; Zhao, C.

    2012-02-01

    Part I. An Introduction to Gravitational Wave Astronomy and Detectors: 1. Gravitational waves D. G. Blair, L. Ju, C. Zhao and E. J. Howell; 2. Sources of gravitational waves D. G. Blair and E. J. Howell; 3. Gravitational wave detectors D. G. Blair, L. Ju, C. Zhao, H. Miao, E. J. Howell, and P. Barriga; 4. Gravitational wave data analysis B. S. Sathyaprakash and B. F. Schutz; 5. Network analysis L. Wen and B. F. Schutz; Part II. Current Laser Interferometer Detectors: Three Case Studies: 6. The Laser Interferometer Gravitational-Wave Observatory P. Fritschel; 7. The VIRGO detector S. Braccini; 8. GEO 600 H. Lück and H. Grote; Part III. Technology for Advanced Gravitational Wave Detectors: 9. Lasers for high optical power interferometers B. Willke and M. Frede; 10. Thermal noise, suspensions and test masses L. Ju, G. Harry and B. Lee; 11. Vibration isolation: Part 1. Seismic isolation for advanced LIGO B. Lantz; Part 2. Passive isolation J-C. Dumas; 12. Interferometer sensing and control P. Barriga; 13. Stabilizing interferometers against high optical power effects C. Zhao, L. Ju, S. Gras and D. G. Blair; Part IV. Technology for Third Generation Gravitational Wave Detectors: 14. Cryogenic interferometers J. Degallaix; 15. Quantum theory of laser-interferometer GW detectors H. Miao and Y. Chen; 16. ET. A third generation observatory M. Punturo and H. Lück; Index.

  6. Advanced detectors and signal processing

    NASA Technical Reports Server (NTRS)

    Greve, D. W.; Rasky, P. H. L.; Kryder, M. H.

    1986-01-01

    Continued progress is reported toward development of a silicon on garnet technology which would allow fabrication of advanced detection and signal processing circuits on bubble memories. The first integrated detectors and propagation patterns have been designed and incorporated on a new mask set. In addition, annealing studies on spacer layers are performed. Based on those studies, a new double layer spacer is proposed which should reduce contamination of the silicon originating in the substrate. Finally, the magnetic sensitivity of uncontaminated detectors from the last lot of wafers is measured. The measured sensitivity is lower than anticipated but still higher than present magnetoresistive detectors.

  7. Advanced Radiation Detector Development

    SciTech Connect

    The University of Michigan

    1998-07-01

    Since our last progress report, the project at The University of Michigan has continued to concentrate on the development of gamma ray spectrometers fabricated from cadmium zinc telluride (CZT). This material is capable of providing energy resolution that is superior to that of scintillation detectors, while avoiding the necessity for cooling associated with germanium systems. In our past reports, we have described one approach (the coplanar grid electrode) that we have used to partially overcome some of the major limitations on charge collection that is found in samples of CZT. This approach largely eliminates the effect of hole motion in the formation of the output signal, and therefore leads to pulses that depend only on the motion of a single carrier (electrons). Since electrons move much more readily through CZT than do holes, much better energy resolution can be achieved under these conditions. In our past reports, we have described a 1 cm cube CZT spectrometer fitted with coplanar grids that achieved an energy resolution of 1.8% from the entire volume of the crystal. This still represents, to our knowledge, the best energy resolution ever demonstrated in a CZT detector of this size.

  8. Report on Advanced Detector Development

    SciTech Connect

    James K. Jewell

    2012-09-01

    Neutron, gamma and charged particle detection improvements are key to supporting many of the foreseen measurements and systems envisioned in the R&D programs and the future fuel cycle requirements, such as basic nuclear physics and data, modeling and simulation, reactor instrumentation, criticality safety, materials management and safeguards. This task will focus on the developmental needs of the FCR&D experimental programs, such as elastic/inelastic scattering, total cross sections and fission neutron spectra measurements, and will leverage a number of existing neutron detector development efforts and programs, such as those at LANL, PNNL, INL, and IAC as well as those at many universities, some of whom are funded under NE grants and contracts. Novel materials and fabrication processes combined with state-of-the-art electronics and computing provide new opportunities for revolutionary detector systems that will be able to meet the high precision needs of the program. This work will be closely coordinated with the Nuclear Data Crosscut. The Advanced Detector Development effort is a broadly-focused activity that supports the development of improved nuclear data measurements and improved detection of nuclear reactions and reactor conditions. This work supports the design and construction of large-scale, multiple component detectors to provide nuclear reaction data of unprecedented quality and precision. Examples include the Time Projection Chamber (TPC) and the DANCE detector at LANL. This work also supports the fabrication and end-user application of novel scintillator materials detection and monitoring.

  9. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  10. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at the NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  11. Advanced Space Radiation Detector Technology Development

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art (SOA) instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  12. Advanced ACTPol Cryogenic Detector Arrays and Readout

    NASA Astrophysics Data System (ADS)

    Henderson, S. W.; Allison, R.; Austermann, J.; Baildon, T.; Battaglia, N.; Beall, J. A.; Becker, D.; De Bernardis, F.; Bond, J. R.; Calabrese, E.; Choi, S. K.; Coughlin, K. P.; Crowley, K. T.; Datta, R.; Devlin, M. J.; Duff, S. M.; Dunkley, J.; Dünner, R.; van Engelen, A.; Gallardo, P. A.; Grace, E.; Hasselfield, M.; Hills, F.; Hilton, G. C.; Hincks, A. D.; Hloẑek, R.; Ho, S. P.; Hubmayr, J.; Huffenberger, K.; Hughes, J. P.; Irwin, K. D.; Koopman, B. J.; Kosowsky, A. B.; Li, D.; McMahon, J.; Munson, C.; Nati, F.; Newburgh, L.; Niemack, M. D.; Niraula, P.; Page, L. A.; Pappas, C. G.; Salatino, M.; Schillaci, A.; Schmitt, B. L.; Sehgal, N.; Sherwin, B. D.; Sievers, J. L.; Simon, S. M.; Spergel, D. N.; Staggs, S. T.; Stevens, J. R.; Thornton, R.; Van Lanen, J.; Vavagiakis, E. M.; Ward, J. T.; Wollack, E. J.

    2016-03-01

    Advanced ACTPol is a polarization-sensitive upgrade for the 6 m aperture Atacama Cosmology Telescope, adding new frequencies and increasing sensitivity over the previous ACTPol receiver. In 2016, Advanced ACTPol will begin to map approximately half the sky in five frequency bands (28-230 GHz). Its maps of primary and secondary cosmic microwave background anisotropies—imaged in intensity and polarization at few arcminute-scale resolution—will enable precision cosmological constraints and also a wide array of cross-correlation science that probes the expansion history of the universe and the growth of structure via gravitational collapse. To accomplish these scientific goals, the Advanced ACTPol receiver will be a significant upgrade to the ACTPol receiver, including four new multichroic arrays of cryogenic, feedhorn-coupled AlMn transition edge sensor polarimeters (fabricated on 150 mm diameter wafers); a system of continuously rotating meta-material silicon half-wave plates; and a new multiplexing readout architecture which uses superconducting quantum interference devices and time division to achieve a 64-row multiplexing factor. Here we present the status and scientific goals of the Advanced ACTPol instrument, emphasizing the design and implementation of the Advanced ACTPol cryogenic detector arrays.

  13. Advanced ACTPol Cryogenic Detector Arrays and Readout

    NASA Astrophysics Data System (ADS)

    Henderson, S. W.; Allison, R.; Austermann, J.; Baildon, T.; Battaglia, N.; Beall, J. A.; Becker, D.; De Bernardis, F.; Bond, J. R.; Calabrese, E.; Choi, S. K.; Coughlin, K. P.; Crowley, K. T.; Datta, R.; Devlin, M. J.; Duff, S. M.; Dunkley, J.; Dünner, R.; van Engelen, A.; Gallardo, P. A.; Grace, E.; Hasselfield, M.; Hills, F.; Hilton, G. C.; Hincks, A. D.; Hloẑek, R.; Ho, S. P.; Hubmayr, J.; Huffenberger, K.; Hughes, J. P.; Irwin, K. D.; Koopman, B. J.; Kosowsky, A. B.; Li, D.; McMahon, J.; Munson, C.; Nati, F.; Newburgh, L.; Niemack, M. D.; Niraula, P.; Page, L. A.; Pappas, C. G.; Salatino, M.; Schillaci, A.; Schmitt, B. L.; Sehgal, N.; Sherwin, B. D.; Sievers, J. L.; Simon, S. M.; Spergel, D. N.; Staggs, S. T.; Stevens, J. R.; Thornton, R.; Van Lanen, J.; Vavagiakis, E. M.; Ward, J. T.; Wollack, E. J.

    2016-08-01

    Advanced ACTPol is a polarization-sensitive upgrade for the 6 m aperture Atacama Cosmology Telescope, adding new frequencies and increasing sensitivity over the previous ACTPol receiver. In 2016, Advanced ACTPol will begin to map approximately half the sky in five frequency bands (28-230 GHz). Its maps of primary and secondary cosmic microwave background anisotropies—imaged in intensity and polarization at few arcminute-scale resolution—will enable precision cosmological constraints and also a wide array of cross-correlation science that probes the expansion history of the universe and the growth of structure via gravitational collapse. To accomplish these scientific goals, the Advanced ACTPol receiver will be a significant upgrade to the ACTPol receiver, including four new multichroic arrays of cryogenic, feedhorn-coupled AlMn transition edge sensor polarimeters (fabricated on 150 mm diameter wafers); a system of continuously rotating meta-material silicon half-wave plates; and a new multiplexing readout architecture which uses superconducting quantum interference devices and time division to achieve a 64-row multiplexing factor. Here we present the status and scientific goals of the Advanced ACTPol instrument, emphasizing the design and implementation of the Advanced ACTPol cryogenic detector arrays.

  14. Advanced ACTPol Cryogenic Detector Arrays and Readout

    NASA Technical Reports Server (NTRS)

    Henderson, S.W.; Battaglia, N.; Wollack, E. J.; Allison, R.; Austermann, J.; Baildon, T.; Beall, J. A.; Becker, D.; De Bernardis, F.; Bond, J. R.

    2016-01-01

    Advanced ACTPol is a polarization-sensitive upgrade for the 6 m aperture Atacama Cosmology Telescope, adding new frequencies and increasing sensitivity over the previous ACTPol receiver. In 2016, Advanced ACTPol will begin to map approximately half the sky in five frequency bands (28-230 GHz). Its maps of primary and secondary cosmic microwave background anisotropies-imaged in intensity and polarization at few arcminute-scale resolution-will enable precision cosmological constraints and also awide array of cross-correlation science that probes the expansion history of the universe and the growth of structure via gravitational collapse. To accomplish these scientific goals, the AdvancedACTPol receiver will be a significant upgrade to the ACTPol receiver, including four new multichroic arrays of cryogenic, feedhorn-coupled AlMn transition edge sensor polarimeters (fabricated on 150 mm diameter wafers); a system of continuously rotating meta-material silicon half-wave plates; and a new multiplexing readout architecture which uses superconducting quantum interference devices and time division to achieve a 64-row multiplexing factor. Here we present the status and scientific goals of the Advanced ACTPol instrument, emphasizing the design and implementation of the AdvancedACTPol cryogenic detector arrays.

  15. Market for advanced humanitarian mine detectors

    NASA Astrophysics Data System (ADS)

    Newnham, Peter; Daniels, David J.

    2001-10-01

    Uncleared landmines and unexploded ordnance remain a major humanitarian and economic threat in over 60 countries. It is estimated that world wide over US 60 million was spent on mien clearance in 1999. Most of this funding is provided by government aid, often channeled via the UN or European Community. The minefield threat is very varied, with many different types of mien, UXO, terrain and climate type. To cope with this variety a range of demining techniques are used: mechanical techniques such as flails are used for vegetation clearance, however the majority of demining work is still carried out by manual deminers using metal detectors and prodders. Over the last 5 years there has been considerable interest within the scientific and engineering communities in the application of advanced technologies to improve the safety and efficiency of this work. Nevertheless few new products have been introduced into, and accepted by, the demining community. Despite the high political profile of the landmine problem very little e hard dat is available on the real characteristics of the demining equipment market. As part of a European Union supported program to evacuate a multi-sensor handheld mien detector concept, Thales and ERA Technology Ltd have carried out an in-depth assessment of this market. This paper describes the cost- benefits that could accrue to the demining community associated with use of advanced equipment under appropriate conditions and the equipment requirements that result. The dynamics of the demining equipment market and the barriers to entry are discussed.

  16. Interagency Advanced Power Group -- Steering group meeting minutes

    SciTech Connect

    Not Available

    1993-11-18

    This document contains the draft meeting minutes of the Steering Group of the Interagency Advanced Power Group. Included are the discussions resulting from the presentation of working group reports and the results of a discussion of IAPG policies and procedures. In the appendix are the reports of the following working groups: Electrical, Mechanical, Solar, and Systems.

  17. Localization of gravitational wave sources with networks of advanced detectors

    SciTech Connect

    Klimenko, S.; Mitselmakher, G.; Pankow, C.; Vedovato, G.; Drago, M.; Prodi, G.; Mazzolo, G.; Salemi, F.; Re, V.; Yakushin, I.

    2011-05-15

    Coincident observations with gravitational wave (GW) detectors and other astronomical instruments are among the main objectives of the experiments with the network of LIGO, Virgo, and GEO detectors. They will become a necessary part of the future GW astronomy as the next generation of advanced detectors comes online. The success of such joint observations directly depends on the source localization capabilities of the GW detectors. In this paper we present studies of the sky localization of transient GW sources with the future advanced detector networks and describe their fundamental properties. By reconstructing sky coordinates of ad hoc signals injected into simulated detector noise, we study the accuracy of the source localization and its dependence on the strength of injected signals, waveforms, and network configurations.

  18. Advanced Group Support Systems and Facilities

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

    1999-01-01

    The document contains the proceedings of the Workshop on Advanced Group Support Systems and Facilities held at NASA Langley Research Center, Hampton, Virginia, July 19-20, 1999. The workshop was jointly sponsored by the University of Virginia Center for Advanced Computational Technology and NASA. Workshop attendees came from NASA, other government agencies, industry, and universities. The objectives of the workshop were to assess the status of advanced group support systems and to identify the potential of these systems for use in future collaborative distributed design and synthesis environments. The presentations covered the current status and effectiveness of different group support systems.

  19. Pre-stabilized Lasers for Advanced Detectors

    NASA Astrophysics Data System (ADS)

    Man, C.-Nary

    Gravitational wave detectors need very stable continuous wave laser sources able to delivering high power beams. Realization of those lasers is a special R&D calling on very low noise controls on very reliable laser sources. After a brief introduction on the laser principles, we review the current laser sources for gravitational wave interferometric detectors, shortly describing the technologies of both solid-state and fiber lasers and amplifiers. A final section addresses the issue of laser pre-stabilization.

  20. Report of the large solenoid detector group

    SciTech Connect

    Hanson, G.G.; Mori, S.; Pondrom, L.G.; Williams, H.H.; Barnett, B.; Barnes, V.; Cashmore, R.; Chiba, M.; DeSalvo, R.; Devlin, T.

    1987-09-01

    This report presents a conceptual design of a large solenoid for studying physics at the SSC. The parameters and nature of the detector have been chosen based on present estimates of what is required to allow the study of heavy quarks, supersymmetry, heavy Higgs particles, WW scattering at large invariant masses, new W and Z bosons, and very large momentum transfer parton-parton scattering. Simply stated, the goal is to obtain optimum detection and identification of electrons, muons, neutrinos, jets, W's and Z's over a large rapidity region. The primary region of interest extends over +-3 units of rapidity, although the calorimetry must extend to +-5.5 units if optimal missing energy resolution is to be obtained. A magnetic field was incorporated because of the importance of identifying the signs of the charges for both electrons and muons and because of the added possibility of identifying tau leptons and secondary vertices. In addition, the existence of a magnetic field may prove useful for studying new physics processes about which we currently have no knowledge. Since hermeticity of the calorimetry is extremely important, the entire central and endcap calorimeters were located inside the solenoid. This does not at the moment seem to produce significant problems (although many issues remain to be resolved) and in fact leads to a very effective muon detector in the central region.

  1. Advanced alignment of the ATLAS inner detector

    NASA Astrophysics Data System (ADS)

    Stahlman, Jonathan M.; Atlas Collaboration

    2013-08-01

    The primary goal of the ATLAS inner detector (ID) is to accurately measure the trajectories of charged particles in the high particle density environment of the large hadron collider (LHC) collisions. This is achieved using a combination of different technologies, including silicon pixels, silicon microstrips, and gaseous drift-tubes, all immersed in a 2 Tesla magnetic field. With nearly 750 k alignable degrees of freedom, it is crucial that an accurate model of the detector positions be produced using an automated and robust algorithm in order to achieve good tracking performance. This has been accomplished using a variety of alignment techniques resulting in near optimal hit and momentum resolutions.

  2. Advances in Detector Technology for Infrared Astronomy

    NASA Technical Reports Server (NTRS)

    McCreight, Craig; Cheng, P. L. (Technical Monitor)

    1995-01-01

    Progress in semiconductor materials and processing technology has allowed the development of infrared detector arrays with unprecedented sensitivity, for imaging and spectroscopic applications in astronomy. The earlier discrete-detector approach has been replaced by large-element (up to 1024 x 1024 pixel), multiplexed devices. Progress has been made against a number of key limiting factors, such as quantum efficiency, noise, spectral response, linearity, and dark current. Future developments will focus on the need for even larger arrays, which operate at higher temperatures.

  3. Advanced digital detectors for neutron imaging.

    SciTech Connect

    Doty, F. Patrick

    2003-12-01

    Neutron interrogation provides unique information valuable for Nonproliferation & Materials Control and other important applications including medicine, airport security, protein crystallography, and corrosion detection. Neutrons probe deep inside massive objects to detect small defects and chemical composition, even through high atomic number materials such as lead. However, current detectors are bulky gas-filled tubes or scintillator/PM tubes, which severely limit many applications. Therefore this project was undertaken to develop new semiconductor radiation detection materials to develop the first direct digital imaging detectors for neutrons. The approach relied on new discovery and characterization of new solid-state sensor materials which convert neutrons directly to electronic signals via reactions BlO(n,a)Li7 and Li6(n,a)T.

  4. Advanced ROICs design for cooled IR detectors

    NASA Astrophysics Data System (ADS)

    Zécri, Michel; Maillart, Patrick; Sanson, Eric; Decaens, Gilbert; Lefoul, Xavier; Baud, Laurent

    2008-04-01

    The CMOS silicon focal plan array technologies hybridized with infrared detectors materials allow to cover a wide range of applications in the field of space, airborne and grounded-based imaging. Regarding other industries which are also using embedded systems, the requirements of such sensor assembly can be seen as very similar; high reliability, low weight, low power, radiation hardness for space applications and cost reduction. Comparing to CCDs technology, excepted the fact that CMOS fabrication uses standard commercial semiconductor foundry, the interest of this technology used in cooled IR sensors is its capability to operate in a wide range of temperature from 300K to cryogenic with a high density of integration and keeping at the same time good performances in term of frequency, noise and power consumption. The CMOS technology roadmap predict aggressive scaling down of device size, transistor threshold voltage, oxide and metal thicknesses to meet the growing demands for higher levels of integration and performance. At the same time infrared detectors manufacturing process is developing IR materials with a tunable cut-off wavelength capable to cover bandwidths from visible to 20μm. The requirements of third generation IR detectors are driving to scaling down the pixel pitch, to develop IR materials with high uniformity on larger formats, to develop Avalanche Photo Diodes (APD) and dual band technologies. These needs in IR detectors technologies developments associated to CMOS technology, used as a readout element, are offering new capabilities and new opportunities for cooled infrared FPAs. The exponential increase of new functionalities on chip, like the active 2D and 3D imaging, the on chip analog to digital conversion, the signal processing on chip, the bicolor, the dual band and DTI (Double Time Integration) mode ...is aiming to enlarge the field of application for cooled IR FPAs challenging by the way the design activity.

  5. Infrared detectors: Advances, challenges and new technologies

    NASA Astrophysics Data System (ADS)

    Karim, Amir; Andersson, Jan Y.

    2013-12-01

    Human knowledge of infrared (IR) radiation is about 200 years old. However it was in the late 20th century that we developed a wide range of smart technologies for detection and started to take advantage for our benefit. Today IR detector technology is in its 3rd generation and comes with challenging demands. Based on the propagation of IR radiation through free space it is divided into different transmission windows. The most interesting for thermal imaging are the mid-wave IR (MWIR) and the long-wave IR (LW IR). Infrared detectors for thermal imaging have a number of applications in industry, security, search & rescue, surveillance, medicine, research, meteorology, climatology and astronomy. Currently high-performance IR imaging technology is mainly based on epitaxially grown structures of the small-bandgap bulk alloy mercury-cadmium-telluride (MCT), indium antimonide (InSb) and GaAs based quantum-well infrared photodetectors (QWIPs), depending on the application and wavelength range. However, they operate at low temperatures requiring costly and bulky cryogenic systems. In addition there is always a need for better performance, which generates possibilities for developing new technologies. Some emerging technologies are quantum dot infrared photodetectors (QDIPs), type-II strained layer super-lattice, and QDIPs with type-II band alignment. In this report a brief review of the current and new technologies for high performance IR detectors, will be presented.

  6. Enhancing the Detector for Advanced Neutron Capture Experiments

    NASA Astrophysics Data System (ADS)

    Couture, A.; Mosby, S.; Baramsai, B.; Bredeweg, T. A.; Jandel, M.; Macon, K.; O'Donnell, J. M.; Rusev, G.; Taddeucci, T. N.; Ullmann, J. L.; Walker, C. L.

    2015-05-01

    The Detector for Advanced Neutron Capture Experiments (DANCE) has been used for extensive studies of neutron capture, gamma decay, photon strength functions, and prompt and delayed fission-gamma emission. Despite these successes, the potential measurements have been limited by the data acquisition hardware. We report on a major upgrade of the DANCE data acquisition that simultaneously enables strait-forward coupling to auxiliary detectors, including high-resolution high-purity germanium detectors and neutron tagging array. The upgrade will enhance the time domain accessible for time-of-flight neutron measurements as well as improve the resolution in the DANCE barium fluoride crystals for photons.

  7. Enhancing the detector for advanced neutron capture experiments

    DOE PAGESBeta

    Couture, A.; Mosby, S.; Baramsai, B.; Bredeweg, T. A.; Jandel, M.; Macon, K.; O’Donnell, J. M.; Rusev, G.; Taddeucci, T. N; Ullmann, J. L.; et al

    2015-05-28

    The Detector for Advanced Neutron Capture Experiments (DANCE) has been used for extensive studies of neutron capture, gamma decay, photon strength functions, and prompt and delayed fission-gamma emission. Despite these successes, the potential measurements have been limited by the data acquisition hardware. We report on a major upgrade of the DANCE data acquisition that simultaneously enables strait-forward coupling to auxiliary detectors, including high-resolution high-purity germanium detectors and neutron tagging array. The upgrade will enhance the time domain accessible for time-of-flight neutron measurements as well as improve the resolution in the DANCE barium fluoride crystals for photons.

  8. Stabilized High Power Laser for Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    Willke, B.; Danzmann, K.; Fallnich, C.; Frede, M.; Heurs, M.; King, P.; Kracht, D.; Kwee, P.; Savage, R.; Seifert, F.; Wilhelm, R.

    2006-03-01

    Second generation gravitational wave detectors require high power lasers with several 100W of output power and with very low temporal and spatial fluctuations. In this paper we discuss possible setups to achieve high laser power and describe a 200W prestabilized laser system (PSL). The PSL noise requirements for advanced gravitational wave detectors will be discussed in general and the stabilization scheme proposed for the Advanced LIGO PSL will be described. Special emphasis will be given to the most demanding power stabilization requiremets and new results (RIN <= 4×10-9/surdHz) will be presented.

  9. Position-sensitive detectors of the detector group at Jülich

    NASA Astrophysics Data System (ADS)

    Engels, R.; Clemens, U.; Kemmerling, G.; Nöldgen, H.; Schelten, J.

    2009-06-01

    The detector group of the Central Institute of Electronics at the Forschungszentrum Jülich GmbH was founded in 1968. First developments aimed at a detector system with a position-sensitive BF 3 proportional counter for small-angle neutron scattering, which was later used at a beamline of the research reactor FRJ2. At the end of the 1970s first measurements were carried out with photomultiplier (PM)-based detector systems linked with a LiI crystal from Harshaw. Based on this experience we started with the spectrum of position-sensitive neutron scintillation detectors, which have been developed and designed in our institute during the last three decades comprising several high-resolution linear and two-dimensional detectors. The general design of those detectors is based on a modified Anger principle using an array of PMs and a 1 mm 6Li glass scintillator. The sensitive detector area varies on the type of the PMs used and is related to the spatial resolution of the detector type. The neutron sensitivity at 1 Å is about 65% and the remaining gamma sensitivity is less than 10 -4 with a maximum count rate up to 500 kHz depending on the used detector system.

  10. Noise Performance of the Advanced LIGO Detectors

    NASA Astrophysics Data System (ADS)

    Hall, Evan; LIGO Scientific Collaboration

    2016-03-01

    Advanced LIGO has completed a four-month search for gravitational wave events using two 4-km laser interferometers separated by a 3000 km baseline. These instruments can sense spacetime strain to better than 10-23 /Hz 1 / 2 in their most sensitive frequency band (80 Hz to 400 Hz). The interferometers' sensitivity is limited by a variety of noise sources, including thermal fluctuations of the test masses and their suspensions, quantum and classical fluctuations of the laser light used to interrogate the test masses, residual environmental disturbances, and noises arising from the sensing and control of the interferometers' length and angular degrees of freedom. We present a budget of these noise sources as they appeared during the first observing run, and discuss ongoing improvements as we look forward to Advanced LIGO achieving full design sensitivity. LIGO was constructed by the California Institute of Technology and Massachusetts Institute of Technology with funding from the National Science Foundation and operates under cooperative agreement PHY-0757058.

  11. Advanced radiation detector development: Advanced semiconductor detector development: Development of a oom-temperature, gamma ray detector using gallium arsenide to develop an electrode detector

    SciTech Connect

    Knoll, G.F.

    1995-11-01

    The advanced detector development project at the University of Michigan has completed the first full year of its current funding. Our general goals are the development of radiation detectors and spectrometers that are capable of portable room temperature operation. Over the past 12 months, we have worked primarily in the development of semiconductor spectrometers with {open_quotes}single carrier{close_quotes} response that offer the promise of room temperature operation and good energy resolution in gamma ray spectroscopy. We have also begun a small scale effort at investigating the properties of a small non-spectroscopic detector system with directional characteristics that will allow identification of the approximate direction in which gamma rays are incident. These activities have made use of the extensive clean room facilities at the University of Michigan for semiconductor device fabrication, and also the radiation measurement capabilities provided in our laboratory in the Phoenix Building on the North Campus. In addition to our laboratory based activities, Professor Knoll has also been a participant in several Department of Energy review activities held in the Forrestal Building and at the Germantown site. The most recent of these has been service on a DOE review panel chaired by Dr. Hap Lamonds that is reviewing the detector development programs supported through the Office of Arms Control and International Security.

  12. Advanced Extravehicular Activity Breakout Group Summary

    NASA Technical Reports Server (NTRS)

    Kosmo, Joseph J.; Perka, Alan; Walz, Carl; Cobb, Sharon; Hanford, Anthony; Eppler, Dean

    2005-01-01

    This viewgraph document summarizes the workings of the Advanced Extravehicular Activity (AEVA) Breakout group in a Martian environment. The group was tasked with: identifying potential contaminants and pathways for AEVA systems with respect to forward and backward contamination; identifying plausible mitigation alternatives and obstacles for pertinent missions; identifying topics that require further research and technology development and discuss development strategies with uncertain Planetary Protection (PP) requirements; Identifying PP requirements that impose the greatest mission/development costs; Identifying PP requirements/topics that require further definition;

  13. Detector for advanced neutron capture experiments at LANSCE

    SciTech Connect

    Ullmann, J. L.; Reifarth, R.; Haight, Robert C.; Hunt, L. F.; O'Donnell, J. M.; Bredeweg, T. A.; Wilhelmy, J. B.; Fowler, Malcolm M.; Vieira, D. J.; Wouters, J. M.; Strottman, D.; Kaeppeler, F.; Heil, M.; Chamberlin, E. P.

    2002-01-01

    The Detector for Advanced Neutron Capture Experiments (DANCE) is a 159-element 4x barium fluoride array designed to study neutron capture on small quantities, 1 mg or less, of radioactive nuclides. It is being built on a 20 m neutron flight path which views the 'upper tier' water moderator at the Manuel J. Lujan Jr. Neutron Scattering Center at the Los Alamos Neutron Science Center. The detector design is based on Monte Carlo calculations which have suggested ways to minimize backgrounds due to neutron scattering events. A data acquisition system based on fast transient digitizers is bcing implemented

  14. The Detector for Advanced Neutron Capture Experiments at LANSCE

    SciTech Connect

    Ullmann, J.L.; Reifarth, R.; Haight, R.C.; Hunt, L.; O'Donnell, J.M.; Rundberg, R.S.; Bredeweg, T.A.; Wilhelmy, J.B.; Fowler, M.M.; Vieira, D.J.; Wouters, J.M.; Strottman, D.D.; Kaeppeler, F.; Heil, M.; Chamberlin, E.P.

    2003-08-26

    The Detector for Advanced Neutron Capture Experiments (DANCE) is a 159-element 4{pi} barium fluoride array designed to study neutron capture on small quantities, 1 mg or less, of radioactive nuclides. It is being built on a 20 m neutron flight path which views the 'upper tier' water moderator at the Manuel J. Lujan Jr. Neutron Scattering Center at the Los Alamos Neutron Science Center. The detector design is based on Monte Carlo calculations which have suggested ways to minimize backgrounds due to neutron scattering events. A data acquisition system based on fast transient digitizers is being implemented.

  15. Developments Toward Monolithic Suspensions for Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    Heptonstall, Alastair; Cantley, Caroline; Crooks, David; Cumming, Alan; Hough, James; Jones, Russell; Martin, Iain; Rowan, Sheila; Cagnoli, Gianpietro

    2008-09-01

    The proposed upgrades to both the LIGO and Virgo gravitational wave observatories will seek to improve detector sensitivity by reducing thermal noise. Based on technologies first implemented at the GEO600 detector, the test mass mirrors will be suspended using fused silica fibres of either circular or rectangular cross section to form monolithic suspensions. In GEO600 cylindrical fused silica fibres were produced using a hydrogen-oxygen flame based machine. Here we report on a new CO2 laser based fibre pulling system under development in Glasgow designed to achieve higher tolerances and reduce contamination of fibres. Preliminary testing of a laser welding process suitable for constructing full scale monolithic suspensions for advanced detectors is described.

  16. The Suitability of Hybrid Waveforms for Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    MacDonald, Ilana; Nissanke, Samaya; Pfeiffer, Harald

    2012-03-01

    Detectors such as Advanced LIGO are expected to measure gravitational wave (GW) signals from compact binaries within the next few years. In order to be able to characterize this type of signal, these detectors require accurate waveform models, which can be constructed by fusing an analytical post-Newtonian (PN) inspiral waveform with a numerical relativity (NR) late-inspiral-merger-ringdown waveform. NR, though the most accurate model, is computationally expensive: the longest simulations to date taking several months to run. PN theory, an analytic approximation to General Relativity, is easy to compute but becomes increasingly inaccurate near merger. Because of this trade-off, it is important to determine the optimal length of the NR waveform, while maintaining the necessary accuracy for GW detectors. We present a study of the sufficient accuracy of PN and NR waveforms for the most demanding usage case: parameter estimation of strong sources in advanced gravitational wave detectors. We perform a comprehensive analysis of errors that enter such ``hybrid waveforms'' in the case of equal- and unequal-mass non-spinning binaries.

  17. Advanced Two-Dimensional Thermal Neutron Detectors for Scattering Studies

    SciTech Connect

    Fried, J.; Harder, J.; Mahler, G.J.; Makowiecki, D.S.; Mead, J.A.; Radeka, V.; Schaknowski, N.A.; Smith, G.C.; Yu, B.

    2002-11-18

    Advances in neutron scattering studies will be given a large boost with the advent of new spallation and reactor sources at present under consideration or construction. An important element for future experiments is a commensurate improvement in neutron detection techniques. At Brookhaven, a development program is under way for greatly increasing the angular coverage, rate capability and resolution of detectors for scattering studies. For example, a curved detector with angular coverage of 120{sup o} by 15{sup o} has recently been developed for protein crystallography at a spallation source. Based on neutron detection using {sup 3}He, the detector has the following major, new attributes: eight identical proportional wire segments operating in parallel, a single gas volume with seamless readout at segment boundaries, parallax errors eliminated in the horizontal plane by the detector's appropriate radius of curvature, high-throughput front-end electronics, position decoding based on high performance digital signal processing. The detector has a global rate capability greater than 1 million per second, position resolution less than 1.5 mm FWHM, timing resolution about 1 {micro}s, efficiency of 50% and 90% at 1{angstrom} and 4 {angstrom} respectively, and an active area 1.5 m x 20 cm.

  18. Advanced Polymers Containing the Phenyltrifluoroethylidene Connecting Group

    NASA Technical Reports Server (NTRS)

    Alstron, William B.; Sivko, Gloria S.

    2006-01-01

    A new, lower cost fluorinated dianhydride based on the phenyltrifluoroethylidene (3F) connecting linkage was invented by the principal author in the early 1980's. New 3F condensation and addition cured polyimides were synthesized with the newly discovered 3F dianhydride and the previously known 3F diamine. As controls, polyimides based on the somewhat analogous higher cost hexafluoroisopropylidene (6F) linkage were also prepared. The short term thermal oxidative stability (TOS), determined by thermal gravimetric analysis (TGA), and the glass transition temperatures (Tg) of 3F dianhydride polyimides were found to be similar to 6F dianhydride polyimides, but the Tg was slightly higher for 3F diamine polyimides than 6F diamine polyimides. Unfortunately, in real time testing, long term TOS of 3F polymers was clearly inferior to 6F polymers. This was due to a 3 to 5 fold greater rate of loss of trifluoromethyl group from 3F versus 6F linkages. However, at shorter times or lower temperatures, 3F TOS was almost comparable to 6F TOS. The wide scope of the 3F technology was also demonstrated to have distinct unique advantages over 6F technology through the use of the 3F pendant phenyl ring as a synthetic site to introduce other functional groups. These groups have been used for the control or modification of polymer properties; an advantage lacking within 6F technology. The synthetic ease by which 3F can be introduced into various types of monomers has lead to the explosion of advanced 3F polyimides and other high performance advanced 3F polymers in the prior decade of 3F polymer literature as cited herein; covering polyimides, substituted polyimides, at least ten types of nonpolyimide 3F polymer modifications, and also the government's nine 3F U.S. patents and corporations' nine 3F U.S. patents.

  19. The Suitability of Hybrid Waveforms for Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    MacDonald, Ilana R.

    The existence of Gravitational Waves from binary black holes is one of the most interesting predictions of General Relativity. These ripples in space-time should be visible to ground-based gravitational wave detectors worldwide in the next few years. One such detector, the Laser Interferometer Gravitational-wave Observatory (LIGO) is in the process of being upgraded to its Advanced sensitivity which should make gravitational wave detections routine. Even so, the signals that LIGO will detect will be faint compared to the detector noise, and so accurate waveform templates are crucial. In this thesis, we present a detailed analysis of the accuracy of hybrid gravitational waveforms. Hybrids are created by stitching a long post-Newtonian inspiral to the late inspiral, merger, and ringdown produced by numerical relativity simulations. We begin our investigation with a study of the systematic errors in the numerical waveform, and errors due to hybridization and choice of detector noise. For current NR waveforms, the largest source of error comes from the unknown high-order terms in the post-Newtonian waveform, which we first explore for equal-mass, non-spinning binaries, and also for unequal-mass, non-spinning binaries. We then consider the potential reduction in hybrid errors if these higher-order terms were known. Finally, we investigate the possibility of using hybrid waveforms as a detection template bank and integrating NR+PN hybrids into the LIGO detection pipeline.

  20. Advances in detector technologies for visible and infrared wavefront sensing

    NASA Astrophysics Data System (ADS)

    Feautrier, Philippe; Gach, Jean-Luc; Downing, Mark; Jorden, Paul; Kolb, Johann; Rothman, Johan; Fusco, Thierry; Balard, Philippe; Stadler, Eric; Guillaume, Christian; Boutolleau, David; Destefanis, Gérard; Lhermet, Nicolas; Pacaud, Olivier; Vuillermet, Michel; Kerlain, Alexandre; Hubin, Norbert; Reyes, Javier; Kasper, Markus; Ivert, Olaf; Suske, Wolfgang; Walker, Andrew; Skegg, Michael; Derelle, Sophie; Deschamps, Joel; Robert, Clélia; Vedrenne, Nicolas; Chazalet, Frédéric; Tanchon, Julien; Trollier, Thierry; Ravex, Alain; Zins, Gérard; Kern, Pierre; Moulin, Thibaut; Preis, Olivier

    2012-07-01

    The purpose of this paper is to give an overview of the state of the art wavefront sensor detectors developments held in Europe for the last decade. The success of the next generation of instruments for 8 to 40-m class telescopes will depend on the ability of Adaptive Optics (AO) systems to provide excellent image quality and stability. This will be achieved by increasing the sampling, wavelength range and correction quality of the wave front error in both spatial and time domains. The modern generation of AO wavefront sensor detectors development started in the late nineties with the CCD50 detector fabricated by e2v technologies under ESO contract for the ESO NACO AO system. With a 128x128 pixels format, this 8 outputs CCD offered a 500 Hz frame rate with a readout noise of 7e-. A major breakthrough has been achieved with the recent development by e2v technologies of the CCD220. This 240x240 pixels 8 outputs EMCCD (CCD with internal multiplication) has been jointly funded by ESO and Europe under the FP6 programme. The CCD220 and the OCAM2 camera that operates the detector are now the most sensitive system in the world for advanced adaptive optics systems, offering less than 0.2 e readout noise at a frame rate of 1500 Hz with negligible dark current. Extremely easy to operate, OCAM2 only needs a 24 V power supply and a modest water cooling circuit. This system, commercialized by First Light Imaging, is extensively described in this paper. An upgrade of OCAM2 is foreseen to boost its frame rate to 2 kHz, opening the window of XAO wavefront sensing for the ELT using 4 synchronized cameras and pyramid wavefront sensing. Since this major success, new developments started in Europe. One is fully dedicated to Natural and Laser Guide Star AO for the E-ELT with ESO involvement. The spot elongation from a LGS Shack Hartman wavefront sensor necessitates an increase of the pixel format. Two detectors are currently developed by e2v. The NGSD will be a 880x840 pixels CMOS

  1. Advanced fiber optic face plate quality detector design

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Su, Liping; Zhao, Jingxia

    2010-10-01

    A fiber optic face plate is defined by a plurality of fibers of transparent material that are fused and compressed together to transmit an image from one end to another end. Fiber optic face plates exhibit utility in the image intensifiers, cathoderay tubes, and other media displays. In this paper, the design of an advanced fiber optic face plate quality detector is presented. Modern optoelectronic imaging techniques are being used to form fiber optic plate transmission images that are suitable for analyzing the quality parameters of fiber optic face plate. The diffusing light from a halogen lamp is condensed by condenser lens then through a fiber optic face plate, a set of lenses are used to magnify the transmission image, a computer controls a long linear CCD to scan the transmission image, a data grabber captures the CCD's output data and the computer transforms the data into frame image for further analysis. Digital image processing techniques are adopted to analyze the transmission image to obtain the required quality parameters. The image analysis software combines the API that a company provided and programed API is used to acquire the quality parameter that a relevant criteria required. With the long linear CCD scanning and image analysis being computerized, it accomplishes the detection of quality parameters of fiber optic face plates automaticly. The detector can replace the manual detection method and can be widely used for the quality detection of fiber optic face plate. Manufacturers of fiber optic face plates can benefit from the detector for quality control.

  2. NASA Advanced Supercomputing (NAS) User Services Group

    NASA Technical Reports Server (NTRS)

    Pandori, John; Hamilton, Chris; Niggley, C. E.; Parks, John W. (Technical Monitor)

    2002-01-01

    This viewgraph presentation provides an overview of NAS (NASA Advanced Supercomputing), its goals, and its mainframe computer assets. Also covered are its functions, including systems monitoring and technical support.

  3. Advanced Antenna-Coupled Superconducting Detector Arrays for CMB Polarimetry

    NASA Astrophysics Data System (ADS)

    Bock, James

    2014-01-01

    We are developing high-sensitivity millimeter-wave detector arrays for measuring the polarization of the cosmic microwave background (CMB). This development is directed to advance the technology readiness of the Inflation Probe mission in NASA's Physics of the Cosmos program. The Inflation Probe is a fourth-generation CMB satellite that will measure the polarization of the CMB to astrophysical limits, characterizing the inflationary polarization signal, mapping large-scale structure based on polarization induced by gravitational lensing, and mapping Galactic magnetic fields through measurements of polarized dust emission. The inflationary polarization signal is produced by a background of gravitational waves from the epoch of inflation, an exponential expansion of space-time in the early universe, with an amplitude that depends on the physical mechanism producing inflation. The inflationary polarization signal may be distinguished by its unique 'B-mode' vector properties from polarization from the density variations that predominantly source CMB temperature anisotropy. Mission concepts for the Inflation Probe are being developed in the US, Europe and Japan. The arrays are based on planar antennas that provide integral beam collimation, polarization analysis, and spectral band definition in a compact lithographed format that eliminates discrete fore-optics such as lenses and feedhorns. The antennas are coupled to transition-edge superconducting bolometers, read out with multiplexed SQUID current amplifiers. The superconducting sensors and readouts developed in this program share common technologies with NASA X-ray and FIR detector applications. Our program targets developments required for space observations, and we discuss our technical progress over the past two years and plans for future development. We are incorporating arrays into active sub-orbital and ground-based experiments, which advance technology readiness while producing state of the art CMB

  4. Delta-doped hybrid advanced detector for low energy particle detection

    NASA Technical Reports Server (NTRS)

    Cunningham, Thomas J. (Inventor); Fossum, Eric R. (Inventor); Nikzad, Shouleh (Inventor); Pain, Bedabrata (Inventor); Soli, George A. (Inventor)

    2000-01-01

    A delta-doped hybrid advanced detector (HAD) is provided which combines at least four types of technologies to create a detector for energetic particles ranging in energy from hundreds of electron volts (eV) to beyond several million eV. The detector is sensitive to photons from visible light to X-rays. The detector is highly energy-sensitive from approximately 10 keV down to hundreds of eV. The detector operates with milliwatt power dissipation, and allows non-sequential readout of the array, enabling various advanced readout schemes.

  5. Delta-doped hybrid advanced detector for low energy particle detection

    NASA Technical Reports Server (NTRS)

    Cunningham, Thomas J. (Inventor); Fossum, Eric R. (Inventor); Nikzad, Shouleh (Inventor); Pain, Bedabrata (Inventor); Soli, George A. (Inventor)

    2002-01-01

    A delta-doped hybrid advanced detector (HAD) is provided which combines at least four types of technologies to create a detector for energetic particles ranging in energy from hundreds of electron volts (eV) to beyond several million eV. The detector is sensitive to photons from visible light to X-rays. The detector is highly energy-sensitive from approximately 10 keV down to hundreds of eV. The detector operates with milliwatt power dissipation, and allows non-sequential readout of the array, enabling various advanced readout schemes.

  6. Interagency Advanced Power Group Steering Group meeting minutes

    SciTech Connect

    Not Available

    1992-11-18

    This document contains presentation overviews and viewgraphs from a meeting military personnel on the subject of power generation and distribution systems for military applications. Mission analysis and directional plans were given for each working group (chemical, mechanical, electrical, nuclear, solar and systems). Attendees represented the US Air Force, Army, Navy, and NASA.

  7. Advanced Gamma-ray Detectors: Science with GRETINA/GRETA

    NASA Astrophysics Data System (ADS)

    Crawford, Heather

    2014-09-01

    In 2007 the NSAC Rare Isotope Beam Task force introduced 17 ``benchmark experimental programs'' to provide a measure of facility performance capabilities for rare-isotope research and to characterize the physics that can be pursued at FRIB. A majority of these topics, and hence the FRIB program and current RIBF programs, will rely on high-resolution, high-efficiency in-flight γ-ray detection. Toward that end, GRETA is proposed to be a high-resolution, high-efficiency 4 π γ-ray spectrometer, consisting of highly segmented germanium detectors grouped in quad-crystal modules. Using pulse shape analysis, the array will be capable of reconstructing the individual interaction points of incident γ-rays. When combined with tracking algorithms, this provides a large increase in sensitivity and resolving power over existing arrays. GRETA, with 30 quad-crystal modules, will allow maximization of the physics opportunities at FRIB, and will play a central role in the science program both with fast-fragmentation and reaccelerated beams. The technology of GRETA, and the capabilities in terms of science have already been demonstrated through the performance of the 1 π spectrometer, GRETINA. Consisting of 7 quad-crystal modules, GRETINA has proven its capabilities in fast-beam experiments at NSCL, a campaign which saw 24 successful experiments which would not have been possible with previous detector technologies. The capabilities of the array in the energy regime of reaccelerated beams is being put to a similar test in the physics campaign currently underway at ANL. The performance and physics accomplishments to date of GRETINA, and a description and path forward to GRETA, the full 4 π tracking array will be discussed. Emphasis will be placed on the role of GRETA or a similar device at facilities like FRIB and RIBF, in terms of experimental capabilities and physics reach. In 2007 the NSAC Rare Isotope Beam Task force introduced 17 ``benchmark experimental programs'' to

  8. Development of an advanced antineutrino detector for reactor monitoring

    NASA Astrophysics Data System (ADS)

    Classen, T.; Bernstein, A.; Bowden, N. S.; Cabrera-Palmer, B.; Ho, A.; Jonkmans, G.; Kogler, L.; Reyna, D.; Sur, B.

    2015-01-01

    Here we present the development of a compact antineutrino detector for the purpose of nuclear reactor monitoring, improving upon a previously successful design. This paper will describe the design improvements of the detector which increases the antineutrino detection efficiency threefold over the previous effort. There are two main design improvements over previous generations of detectors for nuclear reactor monitoring: dual-ended optical readout and single volume detection mass. The dual-ended optical readout eliminates the need for fiducialization and increases the uniformity of the detector's optical response. The containment of the detection mass in a single active volume provides more target mass per detector footprint, a key design criteria for operating within a nuclear power plant. This technology could allow for real-time monitoring of the evolution of a nuclear reactor core, independent of reactor operator declarations of fuel inventories, and may be of interest to the safeguards community.

  9. Advanced Si IR detectors using molecular beam epitaxy

    NASA Technical Reports Server (NTRS)

    Lin, T. L.; Jones, E. W.; George, T.; Ksendzov, A.; Huberman, M. L.

    1991-01-01

    SiGe/Si heterojunction internal photoemission (HIP) long wavelength infrared (LWIR) detectors have been fabricated by MBE. The SiGe/Si HIP detector offers a tailorable spectral response in the long wavelength infrared regime by varying the SiGe/Si heterojunction barrier. Degenerately doped p(+) SiGe layers were grown using elemental boron, as the dopant source allows a low growth temperature. Good crystalline quality was achieved for boron-doped SiGe due to the reduced growth temperature. The dark current density of the boron-doped HIP detectors was found to be thermionic emission limited. HIP detectors with a 0.066 eV were fabricated and characterized using activation energy analysis, corresponding to a 18 micron cutoff wavelength. Photoresponse of the detectors at wavelengths ranging from 2 to 12 microns has been characterized with corresponding quantum efficiencies of 5 - 0.1 percent.

  10. Investigation of Advanced Resonant-Mass Gravitational Radiation Detectors

    NASA Astrophysics Data System (ADS)

    Zhou, Zhiqing

    1994-01-01

    The sensitivity of resonant-mass gravitational radiation detectors depends on both the antenna cross-section and the detector noise. The cross-section is determined by the sound velocity VS and density rho of the antenna material, as well as the antenna geometry. The principal detector noise sources are thermal Nyquist noise and noise due to the readout electromechanical amplifier. The cross-section is proportional to rho V_sp{S}{5} for a given frequency and antenna geometry while the thermal noise is inversely proportional to the antenna's mechanical quality factor Q for a given temperature. Materials with high VS could, in principle, provide about a hundred-fold increase in the antenna cross -section as compared to current generation detectors. In this dissertation we report the results of measurements of the temperature-dependent mechanical losses in several suitable high sound velocity materials. The results show that the signal-to-noise ratios of detectors made of these materials could be improved by a factor of 15 to 100 at 4 K as compared to current detectors with aluminum antennas. A spherical gravitational wave antenna is very promising for gravitational wave astronomy because of its large cross-section, isotropic sky coverage, and the capability it can provide for determining the wave direction. In this dissertation several aspects of spherical detectors, including the eigenfunctions and eigenfrequencies of the normal-modes of an elastic sphere, the energy cross-section, and the response functions that are used to obtain the noise-free solution to the inverse problem are discussed. Using the maximum likelihood estimation method the inverse problem in the presence of noise is solved. We also determine the false-alarm probability and the detection probability for a network of spherical detectors and estimate the detectable event rates for supernovae core collapses and binary coalescences. Six identical cylindrical detectors, with a suitable arrangement of

  11. Advanced μ-bolometer detectors for high-end applications

    NASA Astrophysics Data System (ADS)

    Mizrahi, U.; Schapiro, F.; Bykov, L.; Giladi, A.; Shiloah, N.; Pivnik, I.; Elkind, S.; Maayani, S.; Mordechai, E.; Farbman, O.; Hirsh, Y.; Twitto, A.; Ben-Ezra, M.; Fraenkel, A.

    2012-06-01

    A new generation of high-performance uncooled detector arrays, with 17 and 25 μm pitch, improved sensitivity, and extended spectral response were developed recently by SCD. This development brings the uncooled infrared technology very close to the performance of traditional second generation cooled LWIR detectors, and enables a new range of applications. We demonstrate the use of our Very High Sensitivity (VHS) 25 μm pitch detector with F/2.4, for long range observation systems. We also present the new Wide-Band (WB) detector, where the detector absorption is tuned to both the MWIR and LWIR bands, which is optimal for use in some applications such as situation awareness. Furthermore, in this work we present our 17 μm pitch new family of detectors with different array formats (QVGA, VGA and XGA). These detectors are targeting a wide range of applications, from medium-performance with low Size, Weight and Power (SWaP) applications, up to high-performance imaging applications.

  12. Finite mirror effects in advanced interferometric gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Lundgren, Andrew P.; Bondarescu, Ruxandra; Tsang, David; Bondarescu, Mihai

    2008-02-01

    Thermal noise is expected to be the dominant source of noise in the most sensitive frequency band of second-generation, ground-based gravitational-wave detectors. Reshaping the beam to a flatter, wider profile which probes more of the mirror surface reduces this noise. The “Mesa” beam shape has been proposed for this purpose and was subsequently generalized to a family of hyperboloidal beams with two parameters: twist angle α and beam width D. Varying α allows a continuous transition from the nearly flat (α=0) to the nearly concentric (α=π) Mesa beam configurations. We analytically prove that in the limit D→∞ hyperboloidal beams become Gaussians. The ideal beam choice for reducing thermal noise is the widest possible beam that satisfies the Advanced LIGO (Laser Interferometer Gravitational-wave Observatory) diffraction loss design constraint of 1 part per million (ppm) per bounce for a mirror radius of 17 cm. In the past the diffraction loss has often been calculated using the clipping approximation that, in general, underestimates the diffraction loss. We develop a code using pseudospectral methods to compute the diffraction loss directly from the propagator. We find that the diffraction loss is not a strictly monotonic function of beam width, but has local minima that occur due to finite mirror effects and leads to natural choices of D. For an α=π Mesa beam a local minimum occurs at D=10.67cm and leads to a diffraction loss of 1.4 ppm. We then compute the thermal noise for the entire hyperboloidal family. We find that if one requires a diffraction loss of strictly 1 ppm, the α=0.91π hyperboloidal beam is optimal, leading to the coating thermal noise (the dominant source of noise for fused-silica mirrors) being lower by about 10% than for a Mesa beam while other types of thermal noise decrease as well. We then develop an iterative process that reconstructs the mirror to specifically account for finite mirror effects. This allows us to increase the

  13. Finite mirror effects in advanced interferometric gravitational wave detectors

    SciTech Connect

    Lundgren, Andrew P.; Bondarescu, Ruxandra; Tsang, David; Bondarescu, Mihai

    2008-02-15

    Thermal noise is expected to be the dominant source of noise in the most sensitive frequency band of second-generation, ground-based gravitational-wave detectors. Reshaping the beam to a flatter, wider profile which probes more of the mirror surface reduces this noise. The 'Mesa' beam shape has been proposed for this purpose and was subsequently generalized to a family of hyperboloidal beams with two parameters: twist angle {alpha} and beam width D. Varying {alpha} allows a continuous transition from the nearly flat ({alpha}=0) to the nearly concentric ({alpha}={pi}) Mesa beam configurations. We analytically prove that in the limit D{yields}{infinity} hyperboloidal beams become Gaussians. The ideal beam choice for reducing thermal noise is the widest possible beam that satisfies the Advanced LIGO (Laser Interferometer Gravitational-wave Observatory) diffraction loss design constraint of 1 part per million (ppm) per bounce for a mirror radius of 17 cm. In the past the diffraction loss has often been calculated using the clipping approximation that, in general, underestimates the diffraction loss. We develop a code using pseudospectral methods to compute the diffraction loss directly from the propagator. We find that the diffraction loss is not a strictly monotonic function of beam width, but has local minima that occur due to finite mirror effects and leads to natural choices of D. For an {alpha}={pi} Mesa beam a local minimum occurs at D=10.67 cm and leads to a diffraction loss of 1.4 ppm. We then compute the thermal noise for the entire hyperboloidal family. We find that if one requires a diffraction loss of strictly 1 ppm, the {alpha}=0.91{pi} hyperboloidal beam is optimal, leading to the coating thermal noise (the dominant source of noise for fused-silica mirrors) being lower by about 10% than for a Mesa beam while other types of thermal noise decrease as well. We then develop an iterative process that reconstructs the mirror to specifically account for finite

  14. Advanced Ge detectors for gamma-ray astronomy

    NASA Technical Reports Server (NTRS)

    Varnell, Larry S.

    1991-01-01

    Externally segmented coaxial detectors are fabricated for high efficiency in detecting gamma rays from cosmic sources with good sensitivities. The external background is reduced by enclosing the Ge detector array inside a thick active shield. The outer electrode of the coaxial detectors is subdivided into five segments, and internal beta activity is rejected by operating the segmented detector in a multisegment mode. The multisegment mode requires that events be detected in two or more segments before they are recorded. The full-energy-peak (FEP) efficiency of the unit is tested as a function of the incident gamma-ray energy and of the discriminator threshold of the segments. Measurements of beta-rejection and FEP efficiency are compared with Monte Carlo calculations, and good agreement is noted.

  15. Recent advances in processing and characterization of edgeless detectors

    NASA Astrophysics Data System (ADS)

    Wu, X.; Kalliopuska, J.; Eränen, S.; Virolainen, T.

    2012-02-01

    During past five years VTT has actively developed edgeless detector fabrication process. The straightforward and high yield process relies on ion-implantation to activate the edges of the detector. A recent fabrication process was performed at VTT to provide p-on-n edgeless detectors. The layout contained DC- and AC-coupled strip detector and pixel detectors for Medipix/Timepix readouts. The fabricated detector thicknesses were 50, 100 and 150 μm. Electrical characterization was done for 5 × 5 mm2 edgeless diodes on wafer level. All measured electrical parameters showed a dramatic dependence on the diode thickness. Leakage current was measured below 10 nA/cm2 at full depletion. Calculation using a theoretical approximation indicates the diode surface generation current of less than 300 pA. The breakdown voltages were measured to be above 140 V and increased as a function of diode thickness. Reverse bias of 10 V is enough to fully deplete designed edgeless diodes. Leakage current dependence of temperature was investigated for both p-on-n and previous n-on-n edgeless detectors and results show that the leakage current doubles for every 8.5 degree Celsius rise in temperature. TCAD device simulations reveal that breakdown occurs at the lateral p-n junction where the electric field reaches its highest value. Thick edgeless diodes have wider bulk space that allows electric potential to drop and causes smaller curvature of the equipotential lines. This releases the accumulation of electric field at the corner of anode and increases the breakdown voltage. A good match of the simulated and the measured capacitance-voltage curves enables identification of proper parameters used in the simulation.

  16. Advanced radiation detector development: Advanced semiconductor detector development: Development of a room-temperature, gamma ray detector using gallium arsenide to develop an electrode detector. Annual progress report, September 30, 1994--September 29, 1995

    SciTech Connect

    Knoll, G.F.

    1995-11-01

    The advanced detector development project at the University of Michigan has completed the first full year of its current funding. The general goals are the development of radiation detectors and spectrometers that are capable of portable room temperature operation. Over the past 12 months, the authors have worked primarily in the development of semiconductor spectrometers with ``single carrier`` response that offer the promise of room temperature operation and good energy resolution in gamma ray spectroscopy. They have also begun a small scale effort at investigating the properties of a small non-spectroscopic detector system with directional characteristics that will allow identification of the approximate direction in which gamma rays are incident. These activities have made use of the extensive clean room facilities at the University of Michigan for semiconductor device fabrication, and also the radiation measurement capabilities provided in the laboratory in the Phoenix Building on the North Campus.

  17. The path to the enhanced and advanced LIGO gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Smith, J. R.; LIGO Scientific Collaboration

    2009-06-01

    We report on the status of the Laser Interferometric Gravitational-Wave Observatory (LIGO) and the plans and progress toward Enhanced and Advanced LIGO. The initial LIGO detectors have finished a two-year long data run during which a full year of triple-coincidence data was collected at design sensitivity. Much of this run was also coincident with the data runs of interferometers in Europe, GEO600 and Virgo. The joint analysis of data from this international network of detectors is ongoing. No gravitational wave signals have been detected in analyses completed to date. Currently two of the LIGO detectors are being upgraded to increase their sensitivity in a program called Enhanced LIGO. The Enhanced LIGO detectors will start another roughly one-year long data run with increased sensitivity in 2009. In parallel, construction of Advanced LIGO, a major upgrade to LIGO, has begun. Installation and commissioning of Advanced LIGO hardware at the LIGO sites will commence at the end of the Enhanced LIGO data run in 2011. When fully commissioned, the Advanced LIGO detectors will be ten times as sensitive as the initial LIGO detectors. Advanced LIGO is expected to make several gravitational-wave detections per year.

  18. Collider Detector at Fermilab (CDF): Data from the Top Group's Top Quark Research

    DOE Data Explorer

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group at Fermilab is organized into six working groups, each with a specific focus. The Top group studies the properties of the top quark, the heaviest known fundamental particle. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  19. Collider Detector at Fermilab (CDF): Data from Supersymmetry, New Phenomena Research of the CDF Exotics Group

    DOE Data Explorer

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group at Fermilab is organized into six working groups, each with a specific focus. The Exotics group searches for Supersymmetry and other New Phenomena. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  20. Advances in array detectors for X-ray diffraction techniques.

    PubMed

    Hanley, Quentin S; Denton, M Bonner

    2005-09-01

    Improved focal plane array detector systems are described which can provide improved readout speeds, random addressing and even be employed to simultaneously measure position, intensity and energy. This latter capability promises to rekindle interests in Laue techniques. Simulations of three varieties of foil mask spectrometer in both on- and off-axis configurations indicate that systems of stacked silicon detectors can provide energy measurements within 1% of the true value based on the use of single 'foils' and approximately 10000 photons. An eight-detector hybrid design can provide energy coverage from 4 to 60 keV. Energy resolution can be improved by increased integration time or higher flux experiments. An off-axis spectrometer design in which the angle between the incident beam and the detector system is 45 degrees results in a shift in the optimum energy response of the spectrometer system. In the case of a 200 microm-thick silicon absorber, the energy optimum shifts from 8.7 keV to 10.3 keV as the angle of incidence goes from 0 to 45 degrees. These new designs make better use of incident photons, lower the impact of source flicker through simultaneous rather than sequential collection of intensities, and improve the energy range relative to previously reported systems. PMID:16120985

  1. Advanced Silicon Detectors for High Energy Astrophysics Missions

    NASA Technical Reports Server (NTRS)

    Ricker, George

    2005-01-01

    A viewgraph presentation on the development of silicon detectors for high energy astrophysics missions is presented. The topics include: 1) Background: Motivation for Event-Driven CCD; 2) Report of Grant Activity; 3) Packaged EDCCD; 4) Measured X-ray Energy Resolution of the Gen1 EDCCDs Operated in "Conventional Mode"; and 5) EDCCD Gen 1.5-Lot 1 Planning.

  2. Reducing the suspension thermal noise of advanced gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Hammond, G. D.; Cumming, A. V.; Hough, J.; Kumar, R.; Tokmakov, K.; Reid, S.; Rowan, S.

    2012-06-01

    The international network of gravitational wave detectors is currently undergoing sensitivity upgrades (aLIGO, aVIRGO and GEO-HF) which will lead to the first detection and subsequent observation of a rich variety of astrophysical sources. To obtain a factor of 10 improvement in the strain sensitivity at low frequencies requires the use of ultralow mechanical loss materials and monolithic fused silica suspensions, optimized mirror coatings and the development of cutting edge techniques to super-polish and figure the interferometer optics. The possibility of applying incremental upgrades to the second generation detectors can be realized by making small but significant changes to the suspensions and/or optical mirror coatings. This includes the use of longer suspensions to increase the dissipation dilution, the development of techniques to reduce the surface loss in fused silica suspensions and methods to lower the mechanical loss from the metal springs used to support the test mass. Such upgrades can potentially improve the strain sensitivity by a factor of 2.5. Looking beyond 2015, the development of techniques to further improve the sensitivity by one order of magnitude are discussed. The third generation detectors will be located underground and will be operated at cryogenic temperatures. At low temperatures, silicon is a particularly promising candidate material as it displays good thermal conductivity, high tensile strength and zero thermal expansion coefficient at 120 K, 18 K and T → 0 K.

  3. Beyond Advanced Gravitational Wave Detectors: Beating the Quantum Limit with Squeezed States of Light

    NASA Astrophysics Data System (ADS)

    Barsotti, Lisa

    2013-04-01

    After two decades of technology development, the first direct observation of gravitational waves appears to be imminent. Ground-based interferometric gravitational wave detectors world-wide are about to come back on-line after a major upgrade aimed to significantly improve their sensitivity. As these advanced detectors become a reality, the gravitational wave community is looking at new ways of further expanding their astrophysical reach. The quantum nature of light imposes a fundamental limit to the sensitivity that gravitational wave detectors can achieve, due to statistical fluctuations in the arrival time of photons at the interferometer output (shot noise) and the recoil of the mirrors due to radiation pressure noise. In this talk I will show how mature technology can be used to push interferometric precision measurement beyond the standard quantum limit by means of squeezed states of light, and current ideas on how to integrate this technology into the Advanced detectors of the Laser Interferometer Gravitational wave Observatory (LIGO).

  4. Advanced sensor technologies for high performance infrared detectors

    NASA Astrophysics Data System (ADS)

    Ziegler, J.; Bruder, M.; Finck, M.; Krüger, R.; Menger, P.; Simon, Th.; Wollrab, R.

    2002-06-01

    For high performance IR imaging and seeker systems AIM has established a high yield and reproducible HgCdTe detector technology. For continuous improvement of detector performance, yield and reliability, key processes have been optimized and new approaches have been developed. By a superior CdZnTe Bridgman growth process, dislocation densities < 1×10 5 cm-2 in substrate and epitaxial layer are achieved for all substrates, ensuring high performance focal-plane-arrays, particularly for λ CO=11.5 μm arrays. A new guard ring approach for planar diodes, created by a n +-region in pixel spacing area reduces pixel crosstalk and improves modulation transfer function. For long linear arrays, a multichip-module-technique has been developed, which meets the demands for high temperature-cycle-reliability. In addition, a cycle-to-failure model has been established by cooldown tests on AIM-FPA's to predict cycle-to-failure at existing FPA approach or maximum allowable strain at demanded cycles-to-failure specification.

  5. Advanced Solid State Pixel Detectors for Future High Energy X-ray Missions

    NASA Astrophysics Data System (ADS)

    Harrison, Fiona

    We propose to advance the state of the art in solid state high energy X-ray pixel detectors for astrophysics. This program builds on advanced readout technology developed for suborbital and the NuSTAR space mission, and combines newly-developed CdTe PIN sensors and materials characterization techniques to achieve detectors broad band (1 - 200 keV), sub-keV energy resolution, and 300 micron spatial resolution. The low-noise readout technology will also be taken to the next generation with reduced pixel size, lower noise and significantly reduced dead time.

  6. Mechanical Design and Development of TES Bolometer Detector Arrays for the Advanced ACTPol Experiment

    NASA Technical Reports Server (NTRS)

    Ward, Jonathan T.; Austermann, Jason; Beall, James A.; Choi, Steve K.; Crowley, Kevin T.; Devlin, Mark J.; Duff, Shannon M.; Gallardo, Patricio M.; Henderson, Shawn W.; Ho, Shuay-Pwu Patty; Hilton, Gene; Hubmayr, Johannes; Khavari, Niloufar; Klein, Jeffrey; Koopman, Brian J.; Li, Dale; McMahon, Jeffrey; Mumby, Grace; Nati, Federico; Wollack, Edward J.

    2016-01-01

    The next generation Advanced ACTPol (AdvACT) experiment is currently underway and will consist of four Transition Edge Sensor (TES) bolometer arrays, with three operating together, totaling 5800 detectors on the sky. Building on experience gained with the ACTPol detector arrays, AdvACT will utilize various new technologies, including 150 mm detector wafers equipped with multichroic pixels, allowing for a more densely packed focal plane. Each set of detectors includes a feedhorn array of stacked silicon wafers which form a spline pro le leading to each pixel. This is then followed by a waveguide interface plate, detector wafer, back short cavity plate, and backshort cap. Each array is housed in a custom designed structure manufactured from high purity copper and then gold plated. In addition to the detector array assembly, the array package also encloses cryogenic readout electronics. We present the full mechanical design of the AdvACT high frequency (HF) detector array package along with a detailed look at the detector array stack assemblies. This experiment will also make use of extensive hardware and software previously developed for ACT, which will be modi ed to incorporate the new AdvACT instruments. Therefore, we discuss the integration of all AdvACT arrays with pre-existing ACTPol infrastructure.

  7. LOCALIZATION OF SHORT DURATION GRAVITATIONAL-WAVE TRANSIENTS WITH THE EARLY ADVANCED LIGO AND VIRGO DETECTORS

    SciTech Connect

    Essick, Reed; Vitale, Salvatore; Katsavounidis, Erik; Vedovato, Gabriele; Klimenko, Sergey

    2015-02-20

    The Laser Interferometer Gravitational wave Observatory (LIGO) and Virgo advanced ground-based gravitational-wave detectors will begin collecting science data in 2015. With first detections expected to follow, it is important to quantify how well generic gravitational-wave transients can be localized on the sky. This is crucial for correctly identifying electromagnetic counterparts as well as understanding gravitational-wave physics and source populations. We present a study of sky localization capabilities for two search and parameter estimation algorithms: coherent WaveBurst, a constrained likelihood algorithm operating in close to real-time, and LALInferenceBurst, a Markov chain Monte Carlo parameter estimation algorithm developed to recover generic transient signals with latency of a few hours. Furthermore, we focus on the first few years of the advanced detector era, when we expect to only have two (2015) and later three (2016) operational detectors, all below design sensitivity. These detector configurations can produce significantly different sky localizations, which we quantify in detail. We observe a clear improvement in localization of the average detected signal when progressing from two-detector to three-detector networks, as expected. Although localization depends on the waveform morphology, approximately 50% of detected signals would be imaged after observing 100-200 deg{sup 2} in 2015 and 60-110 deg{sup 2} in 2016, although knowledge of the waveform can reduce this to as little as 22 deg{sup 2}. This is the first comprehensive study on sky localization capabilities for generic transients of the early network of advanced LIGO and Virgo detectors, including the early LIGO-only two-detector configuration.

  8. GW150914: The Advanced LIGO Detectors in the Era of First Discoveries.

    PubMed

    Abbott, B P; Abbott, R; Abbott, T D; Abernathy, M R; Acernese, F; Ackley, K; Adams, C; Adams, T; Addesso, P; Adhikari, R X; Adya, V B; Affeldt, C; Agathos, M; Agatsuma, K; Aggarwal, N; Aguiar, O D; Aiello, L; Ain, A; Ajith, P; Allen, B; Allocca, A; Altin, P A; Anderson, S B; Anderson, W G; Arai, K; Araya, M C; Arceneaux, C C; Areeda, J S; Arnaud, N; Arun, K G; Ascenzi, S; Ashton, G; Ast, M; Aston, S M; Astone, P; Aufmuth, P; Aulbert, C; Babak, S; Bacon, P; Bader, M K M; Baker, P T; Baldaccini, F; Ballardin, G; Ballmer, S W; Barayoga, J C; Barclay, S E; Barish, B C; Barker, D; Barone, F; Barr, B; Barsotti, L; Barsuglia, M; Barta, D; Bartlett, J; Bartos, I; Bassiri, R; Basti, A; Batch, J C; Baune, C; Bavigadda, V; Bazzan, M; Behnke, B; Bejger, M; Bell, A S; Bell, C J; Berger, B K; Bergman, J; Bergmann, G; Berry, C P L; Bersanetti, D; Bertolini, A; Betzwieser, J; Bhagwat, S; Bhandare, R; Bilenko, I A; Billingsley, G; Birch, J; Birney, R; Biscans, S; Bisht, A; Bitossi, M; Biwer, C; Bizouard, M A; Blackburn, J K; Blair, C D; Blair, D G; Blair, R M; Bloemen, S; Bock, O; Bodiya, T P; Boer, M; Bogaert, G; Bogan, C; Bohe, A; Bojtos, P; Bond, C; Bondu, F; Bonnand, R; Boom, B A; Bork, R; Boschi, V; Bose, S; Bouffanais, Y; Bozzi, A; Bradaschia, C; Brady, P R; Braginsky, V B; Branchesi, M; Brau, J E; Briant, T; Brillet, A; Brinkmann, M; Brisson, V; Brockill, P; Brooks, A F; Brown, D A; Brown, D D; Brown, N M; Buchanan, C C; Buikema, A; Bulik, T; Bulten, H J; Buonanno, A; Buskulic, D; Buy, C; Byer, R L; Cadonati, L; Cagnoli, G; Cahillane, C; Calderón Bustillo, J; Callister, T; Calloni, E; Camp, J B; Cannon, K C; Cao, J; Capano, C D; Capocasa, E; Carbognani, F; Caride, S; Casanueva Diaz, J; Casentini, C; Caudill, S; Cavaglià, M; Cavalier, F; Cavalieri, R; Cella, G; Cepeda, C B; Cerboni Baiardi, L; Cerretani, G; Cesarini, E; Chakraborty, R; Chalermsongsak, T; Chamberlin, S J; Chan, M; Chao, S; Charlton, P; Chassande-Mottin, E; Chen, H Y; Chen, Y; Cheng, C; Chincarini, A; Chiummo, A; Cho, H S; Cho, M; Chow, J H; Christensen, N; Chu, Q; Chua, S; Chung, S; Ciani, G; Clara, F; Clark, J A; Cleva, F; Coccia, E; Cohadon, P-F; Colla, A; Collette, C G; Cominsky, L; Constancio, M; Conte, A; Conti, L; Cook, D; Corbitt, T R; Cornish, N; Corsi, A; Cortese, S; Costa, C A; Coughlin, M W; Coughlin, S B; Coulon, J-P; Countryman, S T; Couvares, P; Cowan, E E; Coward, D M; Cowart, M J; Coyne, D C; Coyne, R; Craig, K; Creighton, J D E; Cripe, J; Crowder, S G; Cumming, A; Cunningham, L; Cuoco, E; Dal Canton, T; Danilishin, S L; D'Antonio, S; Danzmann, K; Darman, N S; Dattilo, V; Dave, I; Daveloza, H P; Davier, M; Davies, G S; Daw, E J; Day, R; DeBra, D; Debreczeni, G; Degallaix, J; De Laurentis, M; Deléglise, S; Del Pozzo, W; Denker, T; Dent, T; Dereli, H; Dergachev, V; DeRosa, R T; De Rosa, R; DeSalvo, R; Dhurandhar, S; Díaz, M C; Di Fiore, L; Di Giovanni, M; Di Lieto, A; Di Pace, S; Di Palma, I; Di Virgilio, A; Dojcinoski, G; Dolique, V; Donovan, F; Dooley, K L; Doravari, S; Douglas, R; Downes, T P; Drago, M; Drever, R W P; Driggers, J C; Du, Z; Ducrot, M; Dwyer, S E; Edo, T B; Edwards, M C; Effler, A; Eggenstein, H-B; Ehrens, P; Eichholz, J; Eikenberry, S S; Engels, W; Essick, R C; Etzel, T; Evans, M; Evans, T M; Everett, R; Factourovich, M; Fafone, V; Fair, H; Fairhurst, S; Fan, X; Fang, Q; Farinon, S; Farr, B; Farr, W M; Favata, M; Fays, M; Fehrmann, H; Fejer, M M; Ferrante, I; Ferreira, E C; Ferrini, F; Fidecaro, F; Fiori, I; Fiorucci, D; Fisher, R P; Flaminio, R; Fletcher, M; Fournier, J-D; Franco, S; Frasca, S; Frasconi, F; Frei, Z; Freise, A; Frey, R; Frey, V; Fricke, T T; Fritschel, P; Frolov, V V; Fulda, P; Fyffe, M; Gabbard, H A G; Gair, J R; Gammaitoni, L; Gaonkar, S G; Garufi, F; Gatto, A; Gaur, G; Gehrels, N; Gemme, G; Gendre, B; Genin, E; Gennai, A; George, J; Gergely, L; Germain, V; Ghosh, Archisman; Ghosh, S; Giaime, J A; Giardina, K D; Giazotto, A; Gill, K; Glaefke, A; Goetz, E; Goetz, R; Gondan, L; González, G; Gonzalez Castro, J M; Gopakumar, A; Gordon, N A; Gorodetsky, M L; Gossan, S E; Gosselin, M; Gouaty, R; Graef, C; Graff, P B; Granata, M; Grant, A; Gras, S; Gray, C; Greco, G; Green, A C; Groot, P; Grote, H; Grunewald, S; Guidi, G M; Guo, X; Gupta, A; Gupta, M K; Gushwa, K E; Gustafson, E K; Gustafson, R; Hacker, J J; Hall, B R; Hall, E D; Hammond, G; Haney, M; Hanke, M M; Hanks, J; Hanna, C; Hannam, M D; Hanson, J; Hardwick, T; Haris, K; Harms, J; Harry, G M; Harry, I W; Hart, M J; Hartman, M T; Haster, C-J; Haughian, K; Heidmann, A; Heintze, M C; Heitmann, H; Hello, P; Hemming, G; Hendry, M; Heng, I S; Hennig, J; Heptonstall, A W; Heurs, M; Hild, S; Hoak, D; Hodge, K A; Hofman, D; Hollitt, S E; Holt, K; Holz, D E; Hopkins, P; Hosken, D J; Hough, J; Houston, E A; Howell, E J; Hu, Y M; Huang, S; Huerta, E A; Huet, D; Hughey, B; Husa, S; Huttner, S H; Huynh-Dinh, T; Idrisy, A; Indik, N; Ingram, D R; Inta, R; Isa, H N; Isac, J-M; Isi, M; Islas, G; Isogai, T; Iyer, B R; Izumi, K; Jacqmin, T; Jang, H; Jani, K; Jaranowski, P; Jawahar, S; Jiménez-Forteza, F; Johnson, W W; Jones, D I; Jones, R; Jonker, R J G; Ju, L; Kalaghatgi, C V; Kalogera, V; Kandhasamy, S; Kang, G; Kanner, J B; Karki, S; Kasprzack, M; Katsavounidis, E; Katzman, W; Kaufer, S; Kaur, T; Kawabe, K; Kawazoe, F; Kéfélian, F; Kehl, M S; Keitel, D; Kelley, D B; Kells, W; Kennedy, R; Key, J S; Khalaidovski, A; Khalili, F Y; Khan, I; Khan, S; Khan, Z; Khazanov, E A; Kijbunchoo, N; Kim, C; Kim, J; Kim, K; Kim, Nam-Gyu; Kim, Namjun; Kim, Y-M; King, E J; King, P J; Kinzel, D L; Kissel, J S; Kleybolte, L; Klimenko, S; Koehlenbeck, S M; Kokeyama, K; Koley, S; Kondrashov, V; Kontos, A; Korobko, M; Korth, W Z; Kowalska, I; Kozak, D B; Kringel, V; Królak, A; Krueger, C; Kuehn, G; Kumar, P; Kuo, L; Kutynia, A; Lackey, B D; Landry, M; Lange, J; Lantz, B; Lasky, P D; Lazzarini, A; Lazzaro, C; Leaci, P; Leavey, S; Lebigot, E O; Lee, C H; Lee, H K; Lee, H M; Lee, K; Lenon, A; Leonardi, M; Leong, J R; Leroy, N; Letendre, N; Levin, Y; Levine, B M; Li, T G F; Libson, A; Littenberg, T B; Lockerbie, N A; Logue, J; Lombardi, A L; Lord, J E; Lorenzini, M; Loriette, V; Lormand, M; Losurdo, G; Lough, J D; Lück, H; Lundgren, A P; Luo, J; Lynch, R; Ma, Y; MacDonald, T; Machenschalk, B; MacInnis, M; Macleod, D M; Magaña-Sandoval, F; Magee, R M; Mageswaran, M; Majorana, E; Maksimovic, I; Malvezzi, V; Man, N; Mandel, I; Mandic, V; Mangano, V; Mansell, G L; Manske, M; Mantovani, M; Marchesoni, F; Marion, F; Márka, S; Márka, Z; Markosyan, A S; Maros, E; Martelli, F; Martellini, L; Martin, I W; Martin, R M; Martynov, D V; Marx, J N; Mason, K; Masserot, A; Massinger, T J; Masso-Reid, M; Matichard, F; Matone, L; Mavalvala, N; Mazumder, N; Mazzolo, G; McCarthy, R; McClelland, D E; McCormick, S; McGuire, S C; McIntyre, G; McIver, J; McManus, D J; McWilliams, S T; Meacher, D; Meadors, G D; Meidam, J; Melatos, A; Mendell, G; Mendoza-Gandara, D; Mercer, R A; Merilh, E; Merzougui, M; Meshkov, S; Messenger, C; Messick, C; Meyers, P M; Mezzani, F; Miao, H; Michel, C; Middleton, H; Mikhailov, E E; Milano, L; Miller, J; Millhouse, M; Minenkov, Y; Ming, J; Mirshekari, S; Mishra, C; Mitra, S; Mitrofanov, V P; Mitselmakher, G; Mittleman, R; Moggi, A; Mohan, M; Mohapatra, S R P; Montani, M; Moore, B C; Moore, C J; Moraru, D; Moreno, G; Morriss, S R; Mossavi, K; Mours, B; Mow-Lowry, C M; Mueller, C L; Mueller, G; Muir, A W; Mukherjee, Arunava; Mukherjee, D; Mukherjee, S; Mukund, N; Mullavey, A; Munch, J; Murphy, D J; Murray, P G; Mytidis, A; Nardecchia, I; Naticchioni, L; Nayak, R K; Necula, V; Nedkova, K; Nelemans, G; Neri, M; Neunzert, A; Newton, G; Nguyen, T T; Nielsen, A B; Nissanke, S; Nitz, A; Nocera, F; Nolting, D; Normandin, M E; Nuttall, L K; Oberling, J; Ochsner, E; O'Dell, J; Oelker, E; Ogin, G H; Oh, J J; Oh, S H; Ohme, F; Oliver, M; Oppermann, P; Oram, Richard J; O'Reilly, B; O'Shaughnessy, R; Ottaway, D J; Ottens, R S; Overmier, H; Owen, B J; Pai, A; Pai, S A; Palamos, J R; Palashov, O; Palomba, C; Pal-Singh, A; Pan, H; Pankow, C; Pannarale, F; Pant, B C; Paoletti, F; Paoli, A; Papa, M A; Paris, H R; Parker, W; Pascucci, D; Pasqualetti, A; Passaquieti, R; Passuello, D; Patricelli, B; Patrick, Z; Pearlstone, B L; Pedraza, M; Pedurand, R; Pekowsky, L; Pele, A; Penn, S; Perreca, A; Phelps, M; Piccinni, O; Pichot, M; Piergiovanni, F; Pierro, V; Pillant, G; Pinard, L; Pinto, I M; Pitkin, M; Poggiani, R; Popolizio, P; Post, A; Powell, J; Prasad, J; Predoi, V; Premachandra, S S; Prestegard, T; Price, L R; Prijatelj, M; Principe, M; Privitera, S; Prodi, G A; Prokhorov, L; Puncken, O; Punturo, M; Puppo, P; Pürrer, M; Qi, H; Qin, J; Quetschke, V; Quintero, E A; Quitzow-James, R; Raab, F J; Rabeling, D S; Radkins, H; Raffai, P; Raja, S; Rakhmanov, M; Rapagnani, P; Raymond, V; Razzano, M; Re, V; Read, J; Reed, C M; Regimbau, T; Rei, L; Reid, S; Reitze, D H; Rew, H; Reyes, S D; Ricci, F; Riles, K; Robertson, N A; Robie, R; Robinet, F; Rocchi, A; Rolland, L; Rollins, J G; Roma, V J; Romano, R; Romanov, G; Romie, J H; Rosińska, D; Rowan, S; Rüdiger, A; Ruggi, P; Ryan, K; Sachdev, S; Sadecki, T; Sadeghian, L; Salconi, L; Saleem, M; Salemi, F; Samajdar, A; Sammut, L; Sanchez, E J; Sandberg, V; Sandeen, B; Sanders, J R; Sassolas, B; Sathyaprakash, B S; Saulson, P R; Sauter, O; Savage, R L; Sawadsky, A; Schale, P; Schilling, R; Schmidt, J; Schmidt, P; Schnabel, R; Schofield, R M S; Schönbeck, A; Schreiber, E; Schuette, D; Schutz, B F; Scott, J; Scott, S M; Sellers, D; Sengupta, A S; Sentenac, D; Sequino, V; Sergeev, A; Serna, G; Setyawati, Y; Sevigny, A; Shaddock, D A; Shah, S; Shahriar, M S; Shaltev, M; Shao, Z; Shapiro, B; Shawhan, P; Sheperd, A; Shoemaker, D H; Shoemaker, D M; Siellez, K; Siemens, X; Sigg, D; Silva, A D; Simakov, D; Singer, A; Singer, L P; Singh, A; Singh, R; Singhal, A; Sintes, A M; Slagmolen, B J J; Smith, J R; Smith, N D; Smith, R J E; Son, E J; Sorazu, B; Sorrentino, F; Souradeep, T; Srivastava, A K; Staley, A; Steinke, M; Steinlechner, J; Steinlechner, S; Steinmeyer, D; Stephens, B C; Stone, R; Strain, K A; Straniero, N; Stratta, G; Strauss, N A; Strigin, S; Sturani, R; Stuver, A L; Summerscales, T Z; Sun, L; Sutton, P J; Swinkels, B L; Szczepańczyk, M J; Tacca, M; Talukder, D; Tanner, D B; Tápai, M; Tarabrin, S P; Taracchini, A; Taylor, R; Theeg, T; Thirugnanasambandam, M P; Thomas, E G; Thomas, M; Thomas, P; Thorne, K A; Thorne, K S; Thrane, E; Tiwari, S; Tiwari, V; Tokmakov, K V; Tomlinson, C; Tonelli, M; Torres, C V; Torrie, C I; Töyrä, D; Travasso, F; Traylor, G; Trifirò, D; Tringali, M C; Trozzo, L; Tse, M; Turconi, M; Tuyenbayev, D; Ugolini, D; Unnikrishnan, C S; Urban, A L; Usman, S A; Vahlbruch, H; Vajente, G; Valdes, G; van Bakel, N; van Beuzekom, M; van den Brand, J F J; Van Den Broeck, C; Vander-Hyde, D C; van der Schaaf, L; van Heijningen, J V; van Veggel, A A; Vardaro, M; Vass, S; Vasúth, M; Vaulin, R; Vecchio, A; Vedovato, G; Veitch, J; Veitch, P J; Venkateswara, K; Verkindt, D; Vetrano, F; Viceré, A; Vinciguerra, S; Vine, D J; Vinet, J-Y; Vitale, S; Vo, T; Vocca, H; Vorvick, C; Voss, D; Vousden, W D; Vyatchanin, S P; Wade, A R; Wade, L E; Wade, M; Walker, M; Wallace, L; Walsh, S; Wang, G; Wang, H; Wang, M; Wang, X; Wang, Y; Ward, R L; Warner, J; Was, M; Weaver, B; Wei, L-W; Weinert, M; Weinstein, A J; Weiss, R; Welborn, T; Wen, L; Weßels, P; Westphal, T; Wette, K; Whelan, J T; Whitcomb, S E; White, D J; Whiting, B F; Williams, R D; Williamson, A R; Willis, J L; Willke, B; Wimmer, M H; Winkler, W; Wipf, C C; Wittel, H; Woan, G; Worden, J; Wright, J L; Wu, G; Yablon, J; Yam, W; Yamamoto, H; Yancey, C C; Yap, M J; Yu, H; Yvert, M; Zadrożny, A; Zangrando, L; Zanolin, M; Zendri, J-P; Zevin, M; Zhang, F; Zhang, L; Zhang, M; Zhang, Y; Zhao, C; Zhou, M; Zhou, Z; Zhu, X J; Zucker, M E; Zuraw, S E; Zweizig, J

    2016-04-01

    Following a major upgrade, the two advanced detectors of the Laser Interferometer Gravitational-wave Observatory (LIGO) held their first observation run between September 2015 and January 2016. With a strain sensitivity of 10^{-23}/sqrt[Hz] at 100 Hz, the product of observable volume and measurement time exceeded that of all previous runs within the first 16 days of coincident observation. On September 14, 2015, the Advanced LIGO detectors observed a transient gravitational-wave signal determined to be the coalescence of two black holes [B. P. Abbott et al., Phys. Rev. Lett. 116, 061102 (2016)], launching the era of gravitational-wave astronomy. The event, GW150914, was observed with a combined signal-to-noise ratio of 24 in coincidence by the two detectors. Here, we present the main features of the detectors that enabled this observation. At full sensitivity, the Advanced LIGO detectors are designed to deliver another factor of 3 improvement in the signal-to-noise ratio for binary black hole systems similar in mass to GW150914. PMID:27081966

  9. GW150914: The Advanced LIGO Detectors in the Era of First Discoveries

    NASA Astrophysics Data System (ADS)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.; DeRosa, R. T.; De Rosa, R.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Franco, S.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gatto, A.; Gaur, G.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Haris, K.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, C.; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Królak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lück, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandel, I.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P. G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Neri, M.; Neunzert, A.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perreca, A.; Phelps, M.; Piccinni, O.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shah, S.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, N. D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D. J.; Whiting, B. F.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J. L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; ZadroŻny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.; LIGO Scientific Collaboration; Virgo Collaboration

    2016-04-01

    Following a major upgrade, the two advanced detectors of the Laser Interferometer Gravitational-wave Observatory (LIGO) held their first observation run between September 2015 and January 2016. With a strain sensitivity of 10-23/√{Hz } at 100 Hz, the product of observable volume and measurement time exceeded that of all previous runs within the first 16 days of coincident observation. On September 14, 2015, the Advanced LIGO detectors observed a transient gravitational-wave signal determined to be the coalescence of two black holes [B. P. Abbott et al., Phys. Rev. Lett. 116, 061102 (2016)], launching the era of gravitational-wave astronomy. The event, GW150914, was observed with a combined signal-to-noise ratio of 24 in coincidence by the two detectors. Here, we present the main features of the detectors that enabled this observation. At full sensitivity, the Advanced LIGO detectors are designed to deliver another factor of 3 improvement in the signal-to-noise ratio for binary black hole systems similar in mass to GW150914.

  10. Charge mitigation techniques using glow and corona discharges for advanced gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Campsie, P.; Cunningham, L.; Hendry, M.; Hough, J.; Reid, S.; Rowan, S.; Hammond, G. D.

    2011-11-01

    Charging of silica test masses in gravitational wave detectors could potentially become a significant low-frequency noise source for advanced detectors. Charging noise has already been observed and confirmed in the GEO600 detector and is thought to have been observed in one of the LIGO detectors. In this paper, two charge mitigation techniques using glow and corona discharges were investigated to create repeatable and robust procedures. The glow discharge procedure was used to mitigate charge under vacuum and would be intended to be used in the instance where an optic has become charged while the detector is in operation. The corona discharge procedure was used to discharge samples at atmospheric pressure and would be intended to be used to discharge the detector optics during the cleaning of the optics. Both techniques were shown to reduce both polarities of surface charge on fused silica to a level that would not limit advanced LIGO. Measurements of the transmission of samples that had undergone the charge mitigation procedures showed no significant variation in transmission, at a sensitivity of ~ 200 ppm, in TiO2-doped Ta2O5/SiO2 multi-layer coated fused silica.

  11. Seismic Attenuation Technology for the Advanced Virgo Gravitational Wave Detector

    NASA Astrophysics Data System (ADS)

    Beker, M. G.; Blom, M.; van den Brand, J. F. J.; Bulten, H. J.; Hennes, E.; Rabeling, D. S.

    The current interferometric gravitational wave detectors are being upgraded to what are termed 'second generation' devices. Sensitivities will be increased by an order of magnitude and these new instruments are expected to uncover the field of gravitational astronomy. A main challenge in this endeavor is the mitigation of noise induced by seismic motion. Detailed studies with Virgo show that seismic noise can be reinjected into the dark fringe signal. For example, laser beam jitter and backscattered light limit the sensitivity of the interferometer. Here, we focus on seismic attenuators based on compact inverted pendulums in combination with geometric anti-prings to obtain 40 dB of attenuation above 4 Hz in six degrees of freedom. Low frequency resonances (< 0.5 Hz) are damped by using a control system based on input from LVDTs and geophones. Such systems are under development for the seismic attenuation of optical benches operated both in air and vacuum. The design and realization of the seismic attenuation system for the Virgo external injection bench, including its control scheme, will be discussed and stand-alone performance presented.

  12. Advanced Detector and Waveform Digitizer for Water Vapor DIAL Systems

    NASA Technical Reports Server (NTRS)

    Refaat, Tamer F.; Luck, William S., Jr.; DeYoung, Russell J.

    1998-01-01

    Measurement of atmospheric water vapor has become a major requirement for understanding moist-air processes. Differential absorption lidar (DIAL) is a technique best suited for the measurement of atmospheric water vapor. NASA Langley Research Center is continually developing improved DIAL systems. One aspect of current development is focused on the enhancement of a DIAL receiver by applying state-of-the-art technology in building a new compact detection system that will be placed directly on the DIAL receiver telescope. The newly developed detection system has the capability of being digitally interfaced with a simple personal computer, using a discrete input/output interface. This has the potential of transmitting digital data over relatively long distances instead of analog signals, which greatly reduces measurement noise. In this paper, we discuss some results from the new compact water vapor DIAL detection system which includes a silicon based avalanche photodiode (APD) detector, a 14-bit, 10-MHz waveform digitizer, a microcontroller and other auxiliary electronics. All of which are contained on a small printed-circuit-board. This will significantly reduce the weight and volume over the current CAMAC system and eventually will be used in a water vapor DIAL system on an unpiloted atmospheric vehicle (UAV) aircraft, or alternatively on an orbiting spacecraft.

  13. Progress and challenges in advanced ground-based gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Adier, M.; Aguilar, F.; Akutsu, T.; Arain, M. A.; Ando, M.; Anghinolfi, L.; Antonini, P.; Aso, Y.; Barr, B. W.; Barsotti, L.; Beker, M. G.; Bell, A. S.; Bellon, L.; Bertolini, A.; Blair, C.; Blom, M. R.; Bogan, C.; Bond, C.; Bortoli, F. S.; Brown, D.; Buchler, B. C.; Bulten, H. J.; Cagnoli, G.; Canepa, M.; Carbone, L.; Cesarini, E.; Champagnon, B.; Chen, D.; Chincarini, A.; Chtanov, A.; Chua, S. S. Y.; Ciani, G.; Coccia, E.; Conte, A.; Cortese, M.; Daloisio, M.; Damjanic, M.; Day, R. A.; De Ligny, D.; Degallaix, J.; Doets, M.; Dolique, V.; Dooley, K.; Dwyer, S.; Evans, M.; Factourovich, M.; Fafone, V.; Farinon, S.; Feldbaum, D.; Flaminio, R.; Forest, D.; Frajuca, C.; Frede, M.; Freise, A.; Fricke, T.; Friedrich, D.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Geitner, M.; Gemme, G.; Gleason, J.; Goßler, S.; Gordon, N.; Gräf, C.; Granata, M.; Gras, S.; Gross, M.; Grote, H.; Gustafson, R.; Hanke, M.; Heintze, M.; Hennes, E.; Hild, S.; Huttner, S. H.; Ishidoshiro, K.; Izumi, K.; Kawabe, K.; Kawamura, S.; Kawazoe, F.; Kasprzack, M.; Khalaidovski, A.; Kimura, N.; Koike, S.; Kume, T.; Kumeta, A.; Kuroda, K.; Kwee, P.; Lagrange, B.; Lam, P. K.; Landry, M.; Leavey, S.; Leonardi, M.; Li, T.; Liu, Z.; Lorenzini, M.; Losurdo, G.; Lumaca, D.; Macarthur, J.; Magalhaes, N. S.; Majorana, E.; Malvezzi, V.; Mangano, V.; Mansell, G.; Marque, J.; Martin, R.; Martynov, D.; Mavalvala, N.; McClelland, D. E.; Meadors, G. D.; Meier, T.; Mermet, A.; Michel, C.; Minenkov, Y.; Mow-Lowry, C. M.; Mudadu, L.; Mueller, C. L.; Mueller, G.; Mul, F.; Nanda Kumar, D.; Nardecchia, I.; Naticchioni, L.; Neri, M.; Niwa, Y.; Ohashi, M.; Okada, K.; Oppermann, P.; Pinard, L.; Poeld, J.; Prato, M.; Prodi, G. A.; Puncken, O.; Puppo, P.; Quetschke, V.; Reitze, D. H.; Risson, P.; Rocchi, A.; Saito, N.; Saito, Y.; Sakakibara, Y.; Sassolas, B.; Schimmel, A.; Schnabel, R.; Schofield, R. M. S.; Schreiber, E.; Sequino, V.; Serra, E.; Shaddock, D. A.; Shoda, A.; Shoemaker, D. H.; Shibata, K.; Sigg, D.; Smith-Lefebvre, N.; Somiya, K.; Sorazu, B.; Stefszky, M. S.; Strain, K. A.; Straniero, N.; Suzuki, T.; Takahashi, R.; Tanner, D. B.; Tellez, G.; Theeg, T.; Tokoku, C.; Tsubono, K.; Uchiyama, T.; Ueda, S.; Vahlbruch, H.; Vajente, G.; Vorvick, C.; van den Brand, J. F. J.; Wade, A.; Ward, R.; Wessels, P.; Williams, L.; Willke, B.; Winkelmann, L.; Yamamoto, K.; Zendri, J.-P.

    2014-08-01

    The Amaldi 10 Parallel Session C3 on Advanced Gravitational Wave detectors gave an overview of the status and several specific challenges and solutions relevant to the instruments planned for a mid-decade start of observation. Invited overview talks for the Virgo, LIGO, and KAGRA instruments were complemented by more detailed discussions in presentations and posters of some instrument features and designs.

  14. Classification methods for noise transients in advanced gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Powell, Jade; Trifirò, Daniele; Cuoco, Elena; Heng, Ik Siong; Cavaglià, Marco

    2015-11-01

    Noise of non-astrophysical origin will contaminate science data taken by the advanced laser interferometer gravitational-wave observatory and advanced Virgo gravitational-wave detectors. Prompt characterization of instrumental and environmental noise transients will be critical for improving the sensitivity of the advanced detectors in the upcoming science runs. During the science runs of the initial gravitational-wave detectors, noise transients were manually classified by visually examining the time-frequency scan of each event. Here, we present three new algorithms designed for the automatic classification of noise transients in advanced detectors. Two of these algorithms are based on principal component analysis. They are principal component analysis for transients and an adaptation of LALInference burst. The third algorithm is a combination of an event generator called wavelet detection filter and machine learning techniques for classification. We test these algorithms on simulated data sets, and we show their ability to automatically classify transients by frequency, signal to noise ratio and waveform morphology.

  15. Advances in the development of encapsulants for mercuric iodide X-ray detectors

    NASA Technical Reports Server (NTRS)

    Iwanczyk, J. S.; Wang, Y. J.; Schnepple, W. F.; Bradley, J. G.; Albee, A. L.

    1990-01-01

    Advances in the development of protective impermeable encapsulants with high transparency to ultra-low-energy X-rays for use on HgI2 X-ray detectors are reported. Various X-ray fluorescence spectra from coated detectors are presented. The X-ray absorption in the encapsulants has been analyzed using characteristic radiation from various elements. Results suggest that low-energy cutoffs for the detectors are not determined solely by the encapsulating coatings presently employed but are also influenced by the front electrode and surface effects, which can affect the local electric field or the surface recombination velocity. An energy resolution of 182 eV (FWHM) has been achieved for Ni L lines at 850 eV. Improved detector sensitivity to X-ray energies under 700 eV is demonstrated.

  16. Advanced Fluorescence Protein-Based Synapse-Detectors

    PubMed Central

    Lee, Hojin; Oh, Won Chan; Seong, Jihye; Kim, Jinhyun

    2016-01-01

    The complex information-processing capabilities of the central nervous system emerge from intricate patterns of synaptic input-output relationships among various neuronal circuit components. Understanding these capabilities thus requires a precise description of the individual synapses that comprise neural networks. Recent advances in fluorescent protein engineering, along with developments in light-favoring tissue clearing and optical imaging techniques, have rendered light microscopy (LM) a potent candidate for large-scale analyses of synapses, their properties, and their connectivity. Optically imaging newly engineered fluorescent proteins (FPs) tagged to synaptic proteins or microstructures enables the efficient, fine-resolution illumination of synaptic anatomy and function in large neural circuits. Here we review the latest progress in fluorescent protein-based molecular tools for imaging individual synapses and synaptic connectivity. We also identify associated technologies in gene delivery, tissue processing, and computational image analysis that will play a crucial role in bridging the gap between synapse- and system-level neuroscience. PMID:27445785

  17. Advanced Fluorescence Protein-Based Synapse-Detectors.

    PubMed

    Lee, Hojin; Oh, Won Chan; Seong, Jihye; Kim, Jinhyun

    2016-01-01

    The complex information-processing capabilities of the central nervous system emerge from intricate patterns of synaptic input-output relationships among various neuronal circuit components. Understanding these capabilities thus requires a precise description of the individual synapses that comprise neural networks. Recent advances in fluorescent protein engineering, along with developments in light-favoring tissue clearing and optical imaging techniques, have rendered light microscopy (LM) a potent candidate for large-scale analyses of synapses, their properties, and their connectivity. Optically imaging newly engineered fluorescent proteins (FPs) tagged to synaptic proteins or microstructures enables the efficient, fine-resolution illumination of synaptic anatomy and function in large neural circuits. Here we review the latest progress in fluorescent protein-based molecular tools for imaging individual synapses and synaptic connectivity. We also identify associated technologies in gene delivery, tissue processing, and computational image analysis that will play a crucial role in bridging the gap between synapse- and system-level neuroscience. PMID:27445785

  18. Modular detector for deep underwater registration of muons and muon groups

    NASA Technical Reports Server (NTRS)

    Demianov, A. I.; Sarycheva, L. I.; Sinyov, N. B.; Varadanyan, I. N.; Yershov, A. A.

    1985-01-01

    Registration and identification of muons and muon groups penetrating into the ocean depth, can be performed using a modular multilayer detector with high resolution bidimensional readout - deep underwater calorimeter (project NADIR). Laboratory testing of a prototype sensor cell with liquid scintillator in light-tight casing, testifies to the practicability of the full-scale experiment within reasonable expences.

  19. The GOES-R Advanced Baseline Imager: detector spectral response effects on thermal emissive band calibration

    NASA Astrophysics Data System (ADS)

    Pearlman, Aaron J.; Padula, Francis; Cao, Changyong; Wu, Xiangqian

    2015-10-01

    The Advanced Baseline Imager (ABI) will be aboard the National Oceanic and Atmospheric Administration's Geostationary Operational Environmental Satellite R-Series (GOES-R) to supply data needed for operational weather forecasts and long-term climate variability studies, which depend on high quality data. Unlike the heritage operational GOES systems that have two or four detectors per band, ABI has hundreds of detectors per channel requiring calibration coefficients for each one. This increase in number of detectors poses new challenges for next generation sensors as each detector has a unique spectral response function (SRF) even though only one averaged SRF per band is used operationally to calibrate each detector. This simplified processing increases computational efficiency. Using measured system-level SRF data from pre-launch testing, we have the opportunity to characterize the calibration impact using measured SRFs, both per detector and as an average of detector-level SRFs similar to the operational version. We calculated the spectral response impacts for the thermal emissive bands (TEB) theoretically, by simulating the ABI response viewing an ideal blackbody and practically, with the measured ABI response to an external reference blackbody from the pre-launch TEB calibration test. The impacts from the practical case match the theoretical results using an ideal blackbody. The observed brightness temperature trends show structure across the array with magnitudes as large as 0.1 K for and 12 (9.61 µm), and 0.25 K for band 14 (11.2 µm) for a 300 K blackbody. The trends in the raw ABI signal viewing the blackbody support the spectral response measurements results, since they show similar trends in bands 12 (9.61µm), and 14 (11.2 µm), meaning that the spectral effects dominate the response differences between detectors for these bands. We further validated these effects using the radiometric bias calculated between calibrations using the external blackbody and

  20. Detectors

    DOEpatents

    Orr, Christopher Henry; Luff, Craig Janson; Dockray, Thomas; Macarthur, Duncan Whittemore; Bounds, John Alan; Allander, Krag

    2002-01-01

    The apparatus and method provide techniques through which both alpha and beta emission determinations can be made simultaneously using a simple detector structure. The technique uses a beta detector covered in an electrically conducting material, the electrically conducting material discharging ions generated by alpha emissions, and as a consequence providing a measure of those alpha emissions. The technique also offers improved mountings for alpha detectors and other forms of detectors against vibration and the consequential effects vibration has on measurement accuracy.

  1. Low-latency analysis pipeline for compact binary coalescences in the advanced gravitational wave detector era

    NASA Astrophysics Data System (ADS)

    Adams, T.; Buskulic, D.; Germain, V.; Guidi, G. M.; Marion, F.; Montani, M.; Mours, B.; Piergiovanni, F.; Wang, G.

    2016-09-01

    The multi-band template analysis (MBTA) pipeline is a low-latency coincident analysis pipeline for the detection of gravitational waves (GWs) from compact binary coalescences. MBTA runs with a low computational cost, and can identify candidate GW events online with a sub-minute latency. The low computational running cost of MBTA also makes it useful for data quality studies. Events detected by MBTA online can be used to alert astronomical partners for electromagnetic follow-up. We outline the current status of MBTA and give details of recent pipeline upgrades and validation tests that were performed in preparation for the first advanced detector observing period. The MBTA pipeline is ready for the outset of the advanced detector era and the exciting prospects it will bring.

  2. Astronomy and astrophysics with gravitational waves in the Advanced Detector Era

    NASA Astrophysics Data System (ADS)

    Weinstein, Alan J.; Ligo Scientific Collaboration; Virgo Collaboration

    2012-07-01

    With the advanced gravitational wave detectors coming on line in the next 5 years, we expect to make the first detections of gravitational waves from astrophysical sources, and study the properties of the waves themselves as tests of General Relativity. In addition, these gravitational waves will be powerful tools for the study of their astrophysical sources and source populations. They carry information that is quite complementary to what can be learned from electromagnetic or neutrino observations, probing the central gravitational engines that power the electromagnetic emissions. Preparations are being made to enable near-simultaneous observations of both gravitational wave and electromagnetic observations of transient sources, using low-latency search pipelines and rapid sky localization. We will review the many opportunities for multi-messenger astronomy and astrophysics with gravitational waves enabled by the advanced detectors, and the preparations that are being made to quickly and fully exploit them.

  3. Astronomy and astrophysics with gravitational waves in the advanced detector era

    NASA Astrophysics Data System (ADS)

    Weinstein, Alan J.

    2012-06-01

    With the advanced gravitational wave detectors coming on line in the next 5 years, we expect to make the first detections of gravitational waves from astrophysical sources, and study the properties of the waves themselves as tests of general relativity. In addition, these gravitational waves will be powerful tools for the study of their astrophysical sources and source populations. They carry information that is quite complementary to what can be learned from electromagnetic or neutrino observations, probing the central gravitational engines that power the electromagnetic emissions at the outer layers of the source. Preparations are being made to enable near-simultaneous observations of both gravitational wave and electromagnetic observations of transient sources, using low-latency search pipelines and rapid sky localization. We will review the many opportunities for multi-messenger astronomy and astrophysics with gravitational waves enabled by the advanced detectors, and the preparations that are being made to quickly and fully exploit them.

  4. Data acquisition system for an advanced x-ray imaging crystal spectrometer using a segmented position-sensitive detector.

    PubMed

    Nam, U W; Lee, S G; Bak, J G; Moon, M K; Cheon, J K; Lee, C H

    2007-10-01

    A versatile time-to-digital converter based data acquisition system for a segmented position-sensitive detector has been developed. This data acquisition system was successfully demonstrated to a two-segment position-sensitive detector. The data acquisition system will be developed further to support multisegmented position-sensitive detector to improve the photon count rate capability of the advanced x-ray imaging crystal spectrometer system. PMID:17979416

  5. Technology assessment for the advanced life detector. Final technical report, May 1987-January 1988

    SciTech Connect

    Burrows, W.D.; George, D.T.

    1988-01-29

    This report summarizes an assessment of technology available to develop a noninvasive life detector for use on the battlefield. The detectors determine if casualties wearing chemical protective overgarments are alive or dead without further exposing either the casualties or the aidmen to the contaminated environment. Seven technology approaches sponsored by the Department of Defense (comprising 11 devices), four technologies identified in a market survey, and one device described in a Broad Agency Announcement proposal were examined as candidate Advanced Life Detectors. The technologies and instruments surveyed included three transmitter-receiver technologies, an electrocardiogram (ECG) technology, pacemaker-transmitter/receiver, dry electrode heart rate monitor, five microwave technologies, flash reflectance oximetry, an ultrasound technology, a streaming potential technology, a dry electrode ECG monitor coupled to a microphone, a statometric technique for determining heart rate and blood pressure, and a vital-signs monitor that determines heart rate and blood pressure using blood pressure cuff and microphones incorporated into the cuff. Analysis of the state-of-the-art of each device indicates that none of them are advanced enough to fulfill all the requirements of the draft Joint Services Operational Requirement. Three of the devices identified are recommended for further evaluation.

  6. Focal Plane Detectors for the Advanced Gamma-Ray Imaging System (AGIS)

    SciTech Connect

    Otte, A. N.; Williams, D. A.; Byrum, K.; Drake, G.; Horan, D.; Smith, A.; Wagner, R. G.; Falcone, A.; Funk, S.; Tajima, H.; Mukherjee, R.

    2008-12-24

    The Advanced Gamma-Ray Imaging System (AGIS) is a concept for the next generation observatory in ground-based very high energy gamma-ray astronomy. Design goals are ten times better sensitivity, higher angular resolution, and a lower energy threshold than existing Cherenkov telescopes. Simulations show that a substantial improvement in angular resolution may be achieved if the pixel diameter is reduced to the order of 0.05 deg, i.e. two to three times smaller than the pixel diameter of current Cherenkov telescope cameras. At these dimensions, photon detectors with smaller physical dimensions can be attractive alternatives to the classical photomultiplier tube (PMT). Furthermore, the operation of an experiment with the size of AGIS requires photon detectors that are among other things more reliable, more durable, and possibly higher efficiency photon detectors. Alternative photon detectors we are considering for AGIS include both silicon photomultipliers (SiPMs) and multi-anode photomultipliers (MAPMTs). Here we present results from laboratory testing of MAPMTs and SiPMs along with results from the first incorporation of these devices into cameras on test bed Cherenkov telescopes.

  7. Advanced combined iodine dispenser and detector. [for microorganism annihilation in potable water

    NASA Technical Reports Server (NTRS)

    Lantz, J. B.; Schubert, F. H.; Jensen, F. C.; Powell, J. D.

    1977-01-01

    A total weight of 1.23 kg (2.7 lb), a total volume of 1213 cu m (74 cu in), and an average power consumption of 5.5W was achieved in the advanced combined iodine dispenser/detector by integrating the detector with the iodine source, arranging all iodinator components within a compact package and lowering the parasitic power to the detector and electronics circuits. These achievements surpassed the design goals of 1.36 kg (3.0 lb), 1671 cu m (102 cu in) and 8W. The reliability and maintainability were improved by reducing the detector lamp power, using an interchangeable lamp concept, making the electronic circuit boards easily accessible, providing redundant water seals and improving the accessibility to the iodine accumulator for refilling. The system was designed to iodinate (to 5 ppm iodine) the fuel cell water generated during 27 seven-day orbiter missions (equivalent to 18,500 kg (40,700 lb) of water) before the unit must be recharged with iodine crystals.

  8. Detectability of eccentric compact binary coalescences with advanced gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Coughlin, M.; Meyers, P.; Thrane, E.; Luo, J.; Christensen, N.

    2015-03-01

    Compact binary coalescences are a promising source of gravitational waves for second-generation interferometric gravitational-wave detectors such as advanced LIGO and advanced Virgo. While most binaries are expected to possess circular orbits, some may be eccentric, for example, if they are formed through dynamical capture. Eccentric orbits can create difficulty for matched filtering searches due to the challenges of creating effective template banks to detect these signals. In previous work, we showed how seedless clustering can be used to detect low-mass (Mtotal≤10 M⊙) compact binary coalescences for both spinning and eccentric systems, assuming a circular post-Newtonian expansion. Here, we describe a parametrization that is designed to maximize sensitivity to low-eccentricity (0 ≤ɛ ≤0.6 ) systems, derived from the analytic equations. We show that this parametrization provides a robust and computationally efficient method for detecting eccentric low-mass compact binaries. Based on these results, we conclude that advanced detectors will have a chance of detecting eccentric binaries if optimistic models prove true. However, a null observation is unlikely to firmly rule out models of eccentric binary populations.

  9. Development of an ultrahigh-performance infrared detector platform for advanced spectroscopic sensing systems

    NASA Astrophysics Data System (ADS)

    Jain, Manish; Wicks, Gary; Marshall, Andrew; Craig, Adam; Golding, Terry; Hossain, Khalid; McEwan, Ken; Howle, Chris

    2014-05-01

    Laser-based stand-off sensing of threat agents (e.g. explosives, toxic industrial chemicals or chemical warfare agents), by detection of distinct infrared spectral absorption signature of these materials, has made significant advances recently. This is due in part to the availability of infrared and terahertz laser sources with significantly improved power and tunability. However, there is a pressing need for a versatile, high performance infrared sensor that can complement and enhance the recent advances achieved in laser technology. This work presents new, high performance infrared detectors based on III-V barrier diodes. Unipolar barrier diodes, such as the nBn, have been very successful in the MWIR using InAs(Sb)-based materials, and in the MWIR and LWIR using type-II InAsSb/InAs superlattice-based materials. This work addresses the extension of the barrier diode architecture into the SWIR region, using GaSb-based and InAs-based materials. The program has resulted in detectors with unmatched performance in the 2-3 μm spectral range. Temperature dependent characterization has shown dark currents to be diffusion limited and equal to, or within a factor of 5, of the Rule 07 expression for Auger-limited HgCdTe detectors. Furthermore, D* values are superior to those of existing detectors in the 2-3 μm band. Of particular significance to spectroscopic sensing systems is the ability to have near-background limited performance at operation temperatures compatible with robust and reliable solid state thermoelectric coolers.

  10. Stabilized high-power laser system for the gravitational wave detector advanced LIGO.

    PubMed

    Kwee, P; Bogan, C; Danzmann, K; Frede, M; Kim, H; King, P; Pöld, J; Puncken, O; Savage, R L; Seifert, F; Wessels, P; Winkelmann, L; Willke, B

    2012-05-01

    An ultra-stable, high-power cw Nd:YAG laser system, developed for the ground-based gravitational wave detector Advanced LIGO (Laser Interferometer Gravitational-Wave Observatory), was comprehensively characterized. Laser power, frequency, beam pointing and beam quality were simultaneously stabilized using different active and passive schemes. The output beam, the performance of the stabilization, and the cross-coupling between different stabilization feedback control loops were characterized and found to fulfill most design requirements. The employed stabilization schemes and the achieved performance are of relevance to many high-precision optical experiments. PMID:22565688

  11. Advanced hand-held mine detector and mine detection neutralization and route marking system overview

    NASA Astrophysics Data System (ADS)

    Burch, Ian A.; Allsopp, David J.

    2000-08-01

    An overview of the UK MOD Applied Research Program for Land Mine Detection. The Defense Evaluation and Research Agency carries out and manages the whole of the UK MOD's Counter Minewarfare Applied Research program both within its own laboratories and in partnership with industrial and academic research organizations. This paper will address two specific counter Minewarfare programs, the Advanced Hand Held Mine Detector which started in April 1995 and the Mine Detection Neutralization and Route Marking System which started in April 1997. Both are multi-sensor systems, incorporating between the metal detection, ground penetrating radar, nuclear quadrupole resonance, ultra-wideband radar, and polarized thermal imaging.

  12. Earth Observing-1 Advanced Land Imager: Dark Current and Noise Characterization and Anomalous Detectors

    NASA Technical Reports Server (NTRS)

    Mendenhall, J. A.

    2001-01-01

    The dark current and noise characteristics of the Earth Observing-1 Advanced Land Imager measured during ground calibration at MIT Lincoln Laboratory are presented. Data were collected for the nominal focal plane operating temperature of 220 K as well as supplemental operating temperatures (215 and 225 K). Dark current baseline values are provided, and noise characterization includes the evaluation of white, coherent, low frequency, and high frequency components. Finally, anomalous detectors, characterized by unusual dark current, noise, gain, or cross-talk properties are investigated.

  13. Application of Pixel-cell Detector Technology for Advanced Neutron Beam Monitors

    SciTech Connect

    Kopp, Daniel M.

    2011-01-11

    Application of Pixel-Cell Detector Technology for Advanced Neutron Beam Monitors Specifications of currently available neutron beam detectors limit their usefulness at intense neutron beams of large-scale national user facilities used for the advanced study of materials. A large number of neutron-scattering experiments require beam monitors to operate in an intense neutron beam flux of >10E+7 neutrons per second per square centimeter. For instance, a 4 cm x 4 cm intense beam flux of 6.25 x 10E+7 n/s/cm2 at the Spallation Neutron Source will put a flux of 1.00 x 10E+9 n/s at the beam monitor. Currently available beam monitors with a typical efficiency of 1 x 10E-4 will need to be replaced in less than two years of operation due to wire and gas degradation issues. There is also a need at some instruments for beam position information that are beyond the capabilities of currently available He-3 and BF3 neutron beam monitors. ORDELA, Inc.’s research under USDOE SBIR Grant (DE-FG02-07ER84844) studied the feasibility of using pixel-cell technology for developing a new generation of stable, long-life neutron beam monitors. The research effort has led to the development and commercialization of advanced neutron beam detectors that will directly benefit the Spallation Neutron Source and other intense neutron sources such as the High Flux Isotope Reactor. A prototypical Pixel-Cell Neutron Beam Monitor was designed and constructed during this research effort. This prototype beam monitor was exposed to an intense neutron beam at the HFIR SNS HB-2 test beam site. Initial measurements on efficiency, uniformity across the detector, and position resolution yielded excellent results. The development and test results have provided the required data to initiate the fabrication and commercialization of this next generation of neutron-detector systems. ORDELA, Inc. has (1) identified low-cost design and fabrication strategies, (2) developed and built pixel-cell detectors and

  14. Collider Detector at Fermilab (CDF): Data from Standard Model and Supersymmetric Higgs Bosons Research of the Higgs Group

    DOE Data Explorer

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group at Fermilab is organized into six working groups, each with a specific focus. The Higgs group searches for Standard Model and Supersymmetric Higgs bosons. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  15. Collider Detector at Fermilab (CDF): Data from the QCD Group's Research into Properties of the Strong Interaction

    DOE Data Explorer

    ,

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group at Fermilab is organized into six working groups, each with a specific focus. The QCD group studies the properties of the strong interaction. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  16. Observing gravitational waves from core-collapse supernovae in the advanced detector era

    NASA Astrophysics Data System (ADS)

    Gossan, S. E.; Sutton, P.; Stuver, A.; Zanolin, M.; Gill, K.; Ott, C. D.

    2016-02-01

    The next galactic core-collapse supernova (CCSN) has already exploded, and its electromagnetic (EM) waves, neutrinos, and gravitational waves (GWs) may arrive at any moment. We present an extensive study on the potential sensitivity of prospective detection scenarios for GWs from CCSNe within 5 Mpc, using realistic noise at the predicted sensitivity of the Advanced LIGO and Advanced Virgo detectors for 2015, 2017, and 2019. We quantify the detectability of GWs from CCSNe within the Milky Way and Large Magellanic Cloud, for which there will be an observed neutrino burst. We also consider extreme GW emission scenarios for more distant CCSNe with an associated EM signature. We find that a three-detector network at design sensitivity will be able to detect neutrino-driven CCSN explosions out to ˜5.5 kpc , while rapidly rotating core collapse will be detectable out to the Large Magellanic Cloud at 50 kpc. Of the phenomenological models for extreme GW emission scenarios considered in this study, such as long-lived bar-mode instabilities and disk fragmentation instabilities, all models considered will be detectable out to M31 at 0.77 Mpc, while the most extreme models will be detectable out to M82 at 3.52 Mpc and beyond.

  17. Observing Gravitational Waves from Core-Collapse Supernovae in the Advanced Detector Era

    NASA Astrophysics Data System (ADS)

    Gossan, Sarah; Sutton, Patrick; Stuver, Amber L.; Zanolin, Michele; Gill, Kiranjyot; Ott, Christian D.

    2016-01-01

    The next galactic core-collapse supernova (CCSN) has already exploded, and its electromagnetic (EM) waves, neutrinos, and gravitational waves (GWs) may arrive at any moment. We present an extensive study on the potential sensitivity of prospective detection scenarios for GWs from CCSNe within 5Mpc, using realistic noise at the predicted sensitivity of the Advanced LIGO and Advanced Virgo detectors for 2015, 2017, and 2019. We quantify the detectability of GWs from CCSNe within the Milky Way and Large Magellanic Cloud, for which there will be an observed neutrino burst. We also consider extreme GW emission scenarios for more distant CCSNe with an associated EM signature. We find that a three detector network at design sensitivity will be able to detect neutrino-driven CCSN explosions out to ~5.5 kpc, while rapidly rotating core collapse will be detectable out to the Large Magellanic Cloud at 50kpc. Of the phenomenological models for extreme GW emission scenarios considered in this study, such as long-lived bar-mode instabilities and disk fragmentation instabilities, all models considered will be detectable out to M31 at 0.77 Mpc, while the most extreme models will be detectable out to M82 at 3.52 Mpc and beyond.

  18. Sensitivity of the Advanced LIGO detectors at the beginning of gravitational wave astronomy

    NASA Astrophysics Data System (ADS)

    Martynov, D. V.; Hall, E. D.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Adams, C.; Adhikari, R. X.; Anderson, R. A.; Anderson, S. B.; Arai, K.; Arain, M. A.; Aston, S. M.; Austin, L.; Ballmer, S. W.; Barbet, M.; Barker, D.; Barr, B.; Barsotti, L.; Bartlett, J.; Barton, M. A.; Bartos, I.; Batch, J. C.; Bell, A. S.; Belopolski, I.; Bergman, J.; Betzwieser, J.; Billingsley, G.; Birch, J.; Biscans, S.; Biwer, C.; Black, E.; Blair, C. D.; Bogan, C.; Bork, R.; Bridges, D. O.; Brooks, A. F.; Celerier, C.; Ciani, G.; Clara, F.; Cook, D.; Countryman, S. T.; Cowart, M. J.; Coyne, D. C.; Cumming, A.; Cunningham, L.; Damjanic, M.; Dannenberg, R.; Danzmann, K.; Costa, C. F. Da Silva; Daw, E. J.; DeBra, D.; DeRosa, R. T.; DeSalvo, R.; Dooley, K. L.; Doravari, S.; Driggers, J. C.; Dwyer, S. E.; Effler, A.; Etzel, T.; Evans, M.; Evans, T. M.; Factourovich, M.; Fair, H.; Feldbaum, D.; Fisher, R. P.; Foley, S.; Frede, M.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Galdi, V.; Giaime, J. A.; Giardina, K. D.; Gleason, J. R.; Goetz, R.; Gras, S.; Gray, C.; Greenhalgh, R. J. S.; Grote, H.; Guido, C. J.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hammond, G.; Hanks, J.; Hanson, J.; Hardwick, T.; Harry, G. M.; Heefner, J.; Heintze, M. C.; Heptonstall, A. W.; Hoak, D.; Hough, J.; Ivanov, A.; Izumi, K.; Jacobson, M.; James, E.; Jones, R.; Kandhasamy, S.; Karki, S.; Kasprzack, M.; Kaufer, S.; Kawabe, K.; Kells, W.; Kijbunchoo, N.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kokeyama, K.; Korth, W. Z.; Kuehn, G.; Kwee, P.; Landry, M.; Lantz, B.; Le Roux, A.; Levine, B. M.; Lewis, J. B.; Lhuillier, V.; Lockerbie, N. A.; Lormand, M.; Lubinski, M. J.; Lundgren, A. P.; MacDonald, T.; MacInnis, M.; Macleod, D. M.; Mageswaran, M.; Mailand, K.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martin, I. W.; Martin, R. M.; Marx, J. N.; Mason, K.; Massinger, T. J.; Matichard, F.; Mavalvala, N.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McIntyre, G.; McIver, J.; Merilh, E. L.; Meyer, M. S.; Meyers, P. M.; Miller, J.; Mittleman, R.; Moreno, G.; Mueller, C. L.; Mueller, G.; Mullavey, A.; Munch, J.; Nuttall, L. K.; Oberling, J.; O'Dell, J.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; Osthelder, C.; Ottaway, D. J.; Overmier, H.; Palamos, J. R.; Paris, H. R.; Parker, W.; Patrick, Z.; Pele, A.; Penn, S.; Phelps, M.; Pickenpack, M.; Pierro, V.; Pinto, I.; Poeld, J.; Principe, M.; Prokhorov, L.; Puncken, O.; Quetschke, V.; Quintero, E. A.; Raab, F. J.; Radkins, H.; Raffai, P.; Ramet, C. R.; Reed, C. M.; Reid, S.; Reitze, D. H.; Robertson, N. A.; Rollins, J. G.; Roma, V. J.; Romie, J. H.; Rowan, S.; Ryan, K.; Sadecki, T.; Sanchez, E. J.; Sandberg, V.; Sannibale, V.; Savage, R. L.; Schofield, R. M. S.; Schultz, B.; Schwinberg, P.; Sellers, D.; Sevigny, A.; Shaddock, D. A.; Shao, Z.; Shapiro, B.; Shawhan, P.; Shoemaker, D. H.; Sigg, D.; Slagmolen, B. J. J.; Smith, J. R.; Smith, M. R.; Smith-Lefebvre, N. D.; Sorazu, B.; Staley, A.; Stein, A. J.; Stochino, A.; Strain, K. A.; Taylor, R.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thrane, E.; Torrie, C. I.; Traylor, G.; Vajente, G.; Valdes, G.; van Veggel, A. A.; Vargas, M.; Vecchio, A.; Veitch, P. J.; Venkateswara, K.; Vo, T.; Vorvick, C.; Waldman, S. J.; Walker, M.; Ward, R. L.; Warner, J.; Weaver, B.; Weiss, R.; Welborn, T.; Weßels, P.; Wilkinson, C.; Willems, P. A.; Williams, L.; Willke, B.; Winkelmann, L.; Wipf, C. C.; Worden, J.; Wu, G.; Yamamoto, H.; Yancey, C. C.; Yu, H.; Zhang, L.; Zucker, M. E.; Zweizig, J.

    2016-06-01

    The Laser Interferometer Gravitational Wave Observatory (LIGO) consists of two widely separated 4 km laser interferometers designed to detect gravitational waves from distant astrophysical sources in the frequency range from 10 Hz to 10 kHz. The first observation run of the Advanced LIGO detectors started in September 2015 and ended in January 2016. A strain sensitivity of better than 10-23/√{Hz } was achieved around 100 Hz. Understanding both the fundamental and the technical noise sources was critical for increasing the astrophysical strain sensitivity. The average distance at which coalescing binary black hole systems with individual masses of 30 M⊙ could be detected above a signal-to-noise ratio (SNR) of 8 was 1.3 Gpc, and the range for binary neutron star inspirals was about 75 Mpc. With respect to the initial detectors, the observable volume of the Universe increased by a factor 69 and 43, respectively. These improvements helped Advanced LIGO to detect the gravitational wave signal from the binary black hole coalescence, known as GW150914.

  19. Modelling an advanced ManPAD with dual band detectors and a rosette scanning seeker head

    NASA Astrophysics Data System (ADS)

    Birchenall, Richard P.; Richardson, Mark A.; Butters, Brian; Walmsley, Roy

    2012-01-01

    Man Portable Air Defence Systems (ManPADs) have been a favoured anti aircraft weapon since their appearance on the military proliferation scene in the mid 1960s. Since this introduction there has been a 'cat and mouse' game of Missile Countermeasures (CMs) and the aircraft protection counter counter measures (CCMs) as missile designers attempt to defeat the aircraft platform protection equipment. Magnesium Teflon Viton (MTV) flares protected the target aircraft until the missile engineers discovered the art of flare rejection using techniques including track memory and track angle bias. These early CCMs relied upon CCM triggering techniques such as the rise rate method which would just sense a sudden increase in target energy and assume that a flare CM had been released by the target aircraft. This was not as reliable as was first thought as aspect changes (bringing another engine into the field of view) or glint from the sun could inadvertently trigger a CCM when not needed. The introduction of dual band detectors in the 1980s saw a major advance in CCM capability allowing comparisons between two distinct IR bands to be made thus allowing the recognition of an MTV flare to occur with minimal false alarms. The development of the rosette scan seeker in the 1980s complemented this advancement allowing the scene in the missile field of view (FOV) to be scanned by a much smaller (1/25) instantaneous FOV (IFOV) with the spectral comparisons being made at each scan point. This took the ManPAD from a basic IR energy detector to a pseudo imaging system capable of analysing individual elements of its overall FOV allowing more complex and robust CCM to be developed. This paper continues the work published in [1,2] and describes the method used to model an advanced ManPAD with a rosette scanning seeker head and robust CCMs similar to the Raytheon Stinger RMP.

  20. Revolutionary visible and infrared sensor detectors for the most advanced astronomical AO systems

    NASA Astrophysics Data System (ADS)

    Feautrier, Philippe; Gach, Jean-Luc; Guieu, Sylvain; Downing, Mark; Jorden, Paul; Rothman, Johan; de Borniol, Eric D.; Balard, Philippe; Stadler, Eric; Guillaume, Christian; Boutolleau, David; Coussement, Jérome; Kolb, Johann; Hubin, Norbert; Derelle, Sophie; Robert, Clélia; Tanchon, Julien; Trollier, Thierry; Ravex, Alain; Zins, Gérard; Kern, Pierre; Moulin, Thibaut; Rochat, Sylvain; Delpoulbé, Alain; Lebouqun, Jean-Baptiste

    2014-07-01

    We report in this paper decisive advance on the detector development for the astronomical applications that require very fast operation. Since the CCD220 and OCAM2 major success, new detector developments started in Europe either for visible and IR wavelengths. Funded by ESO and the FP7 Opticon European network, the NGSD CMOS device is fully dedicated to Natural and Laser Guide Star AO for the E-ELT with strong ESO involvement. The NGSD will be a 880x840 pixels CMOS detector with a readout noise of 3 e (goal 1e) at 700 Hz frame rate and providing digital outputs. A camera development, based on this CMOS device and also funded by the Opticon European network, is ongoing. Another major AO wavefront sensing detector development concerns IR detectors based on Avalanche Photodiode (e- APD) arrays within the RAPID project. Developed by the SOFRADIR and CEA/LETI manufacturers, the latter offers a 320x255 8 outputs 30 microns IR array, sensitive from 0.4 to 3 microns, with less than 2 e readout noise at 1600 fps. A rectangular window can also be programmed to speed up even more the frame rate when the full frame readout is not required. The high QE response, in the range of 70%, is almost flat over this wavelength range. Advanced packaging with miniature cryostat using pulse tube cryocoolers was developed in the frame of this programme in order to allow use on this detector in any type of environment. The characterization results of this device are presented here. Readout noise as low as 1.7 e at 1600 fps has been measured with a 3 microns wavelength cut-off chip and a multiplication gain of 14 obtained with a limited photodiode polarization of 8V. This device also exhibits excellent linearity, lower than 1%. The pulse tube cooling allows smart and easy cooling down to 55 K. Vibrations investigations using centroiding and FFT measurements were performed proving that the miniature pulse tube does not induce measurable vibrations to the optical bench, allowing use of this

  1. Advanced Instruction: Facilitation of Individual Learning Processes in Large Groups

    ERIC Educational Resources Information Center

    Putz, Claus; Intveen, Geesche

    2009-01-01

    By supplying various combinations of advanced instructions and different forms of exercises individual learning processes within the impartation of basic knowledge can be activated and supported at best. The fundamentals of our class "Introduction to spatial-geometric cognition using CAD" are constructional inputs, which systematically induce the…

  2. Inverted pendulum as low-frequency pre-isolation for advanced gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Takamori, A.; Raffai, P.; Márka, S.; DeSalvo, R.; Sannibale, V.; Tariq, H.; Bertolini, A.; Cella, G.; Viboud, N.; Numata, K.; Takahashi, R.; Fukushima, M.

    2007-11-01

    We have developed advanced seismic attenuation systems for Gravitational Wave (GW) detectors. The design consists of an Inverted Pendulum (IP) holding stages of Geometrical Anti-Spring Filters (GASF) and pendula, which isolate the test mass suspension from ground noise. The ultra-low-frequency IP suppresses the horizontal seismic noise, while the GASF suppresses the vertical ground vibrations. The three legs of the IP are supported by cylindrical maraging steel flexural joints. The IP can be tuned to very low frequencies by carefully adjusting its load. As a best result, we have achieved an ultra low, ˜12 mHz pendulum frequency for the system prototype made for Advanced LIGO (Laser Interferometer Gravitational Wave Observatory). The measured quality factor, Q, of this IP, ranging from Q˜2500 (at 0.45 Hz) to Q˜2 (at 12 mHz), is compatible with structural damping, and is proportional to the square of the pendulum frequency. Tunable counterweights allow for precise center-of-percussion tuning to achieve the required attenuation up to the first leg internal resonance (˜60 Hz for advanced LIGO prototype). All measurements are in good agreement with our analytical models. We therefore expect good attenuation in the low-frequency region, from ˜0.1to ˜50 Hz, covering the micro-seismic peak. The extremely soft IP requires minimal control force, which simplifies any needed actuation.

  3. Development of an advanced combined iodine dispenser/detector. [for spacecraft water supplies

    NASA Technical Reports Server (NTRS)

    Lantz, J. B.; Jensen, F. C.; Winkler, H. E.; Schubert, F. A.

    1977-01-01

    Injection of iodine into water is widely used to control microbial growth. An entirely automated device for I2 injection has been developed for spacecraft application. Transfer of I2 into the water from a concentrated form is controlled electrochemically via feedback from an integrated photometric I2 level detector. All components are contained within a package weighing only 1.23 kg (2.7 lb) dry, which occupies only 1213 cu cm (74 cu in) of space, and which has the capacity to iodinate 10,900 kg (24,000 lb) of water of 5 ppm. These features exceed design specifications. The device performed satisfactorily during extended testing at variable water flow rates and temperatures. Designed to meet specifications of the Shuttle Orbiter, the device will find application in the regenerative water systems of advanced spacecraft.

  4. Locking the Advanced LIGO Gravitational Wave Detector: with a focus on the Arm Length Stabilization Technique

    NASA Astrophysics Data System (ADS)

    Staley, Alexa

    2015-11-01

    This thesis begins with an introduction on the theory of general relativity and gravitational waves. Common astrophysical sources are described in Chapter 2. Chapter 3 begins with a description of the installed instrument. A discussion on the detector design sensitivity, limiting noise sources, and estimated detection rates is also given. At the end of Chapte 3, the complications of lock acquisition are highlighted. The arm length stabilization system was introduced to Advanced LIGO as a partial way to solve the difficulties of locking. Chapter 4 discusses the motivation for the use of this scheme and explains the methodology. A detailed discussion on the arm length stabilization model is given, along with the noise budget in Chapters 5 and 6 respectively. The full lock sequence is described in Chapter 7. The thesis concludes with the current status of the interferometers. (Abstract shortened by UMI.).

  5. Applications of Gas Imaging Micro-Well Detectors to an Advanced Compton Telescope

    NASA Technical Reports Server (NTRS)

    Bloser, P. F.; Hunter, S. D.; Ryan, J. M.; McConnell, M. L.; Miller, R. S.; Jackson, T. N.; Bai, B.; Jung, S.

    2003-01-01

    We present a concept for an Advanced Compton Telescope (ACT) based on the use of pixelized gas micro-well detectors to form a three-dimensional electron track imager. A micro-well detector consists of an array of individual micro-patterned proportional counters opposite a planar drift electrode. When combined with thin film transistor array readouts, large gas volumes may be imaged with very good spatial and energy resolution at reasonable cost. The third dimension is determined by timing the drift of the ionization electrons. The primary advantage of this approach is the excellent tracking of the Compton recoil electron that is possible in a gas volume. Such good electron tracking allows us to reduce the point spread function of a single incident photon dramatically, greatly improving the imaging capability and sensitivity. The polarization sensitivity, which relies on events with large Compton scattering angles, is particularly enhanced. We describe a possible ACT implementation of this technique, in which the gas tracking volume is surrounded by a CsI calorimeter, and present our plans to build and test a small prototype over the next three years.

  6. Advances in the growth of alkaline-earth halide single crystals for scintillator detectors

    SciTech Connect

    Boatner, Lynn A; Ramey, Joanne Oxendine; Kolopus, James A; Neal, John S; Cherepy, Nerine; Payne, Stephen A.; Beck, P; Burger, Arnold; Rowe, E; Bhattacharya, P.

    2014-01-01

    Alkaline-earth scintillators such as strontium iodide and other alkaline-earth halides activated with divalent europium represent some of the most efficient and highest energy resolution scintillators for use as gamma-ray detectors in a wide range of applications. These applications include the areas of nuclear nonproliferation, homeland security, the detection of undeclared nuclear material, nuclear physics and materials science, medical diagnostics, space physics, high energy physics, and radiation monitoring systems for first responders, police, and fire/rescue personnel. Recent advances in the growth of large single crystals of these scintillator materials hold the promise of higher crystal yields and significantly lower detector production costs. In the present work, we describe new processing protocols that, when combined with our molten salt filtration methods, have led to advances in achieving a significant reduction of cracking effects during the growth of single crystals of SrI2:Eu2+. In particular, we have found that extended pumping on the molten crystal-growth charge under vacuum for time periods extending up to 48 hours is generally beneficial in compensating for variations in the alkaline-earth halide purity and stoichiometry of the materials as initially supplied by commercial sources. These melt-pumping and processing techniques are now being applied to the purification of CaI2:Eu2+ and some mixed-anion europium-doped alkaline-earth halides prior to single-crystal growth by means of the vertical Bridgman technique. The results of initial studies of the effects of aliovalent doping of SrI2:Eu2+ on the scintillation characteristics of this material are also described.

  7. Advances in the growth of alkaline-Earth halide single crystals for scintillator detectors

    NASA Astrophysics Data System (ADS)

    Boatner, L. A.; Ramey, J. O.; Kolopus, J. A.; Neal, J. S.; Cherepy, N. J.; Beck, P. R.; Payne, S. A.; Burger, A.; Rowe, E.; Bhattacharya, P.

    2014-09-01

    Alkaline-earth scintillators such as strontium iodide and other alkaline-earth halides activated with divalent europium represent some of the most efficient and highest energy resolution scintillators for use as gamma-ray detectors in a wide range of applications. These applications include the areas of nuclear nonproliferation, homeland security, the detection of undeclared nuclear material, nuclear physics and materials science, medical diagnostics, space physics, high energy physics, and radiation monitoring systems for first responders, police, and fire/rescue personnel. Recent advances in the growth of large single crystals of these scintillator materials hold the promise of higher crystal yields and significantly lower detector production costs. In the present work, we describe new processing protocols that, when combined with our molten salt filtration methods, have led to advances in achieving a significant reduction of cracking effects during the growth of single crystals of SrI2:Eu2+. In particular, we have found that extended pumping on the molten crystalgrowth charge under vacuum for time periods extending up to 48 hours is generally beneficial in compensating for variations in the alkaline-earth halide purity and stoichiometry of the materials as initially supplied by commercial sources. These melt-pumping and processing techniques are now being applied to the purification of CaI2:Eu2+ and some mixed-anion europium-doped alkaline-earth halides prior to single-crystal growth by means of the vertical Bridgman technique. The results of initial studies of the effects of aliovalent doping of SrI2:Eu2+ on the scintillation characteristics of this material are also described.

  8. The Detector for Advanced Neutron Capture Experiments: A 4{pi} BaF2 Detector for Neutron Capture Measurements at LANSCE

    SciTech Connect

    Ullmann, J.L.; Esch, E.-I.; Haight, R.C.; Hunt, L.; O'Donnell, J.M.; Reifarth, R.; Agvaanluvsan, U.; Alpizar, A.; Hatarik, R.; Bond, E.M.; Bredeweg, T.A.; Kronenberg, A.; Rundberg, R.S.; Vieira, D.J.; Wilhelmy, J.B.; Folden, C.M.; Hoffman, D.C.; Greife, U.; Schwantes, J.M.; Strottman, D.D.

    2005-05-24

    The Detector for Advanced Neutron Capture Experiments (DANCE) is a 162-element 4{pi} BaF2 array designed to make neutron capture cross-section measurements on rare or radioactive targets with masses as little as one milligram. Accurate capture cross sections are needed in many research areas, including stellar nucleosynthesis, advanced nuclear fuel cycles, waste transmutation, and other applied programs. These cross sections are difficult to calculate accurately and must be measured. The design and initial performance results of DANCE is discussed.

  9. Recruiting, retaining, and advancing careers for employees from underrepresented groups.

    PubMed

    Smith, Toni C; Ingersoll, Gail L; Robinson, Regina; Hercules, Hazeldene; Carey, Janet

    2008-04-01

    In response to the need to increase the number of persons from underrepresented groups working in acute care settings, 2 hospitals in upstate New York implemented a multidimensional workforce development project targeting existing and new employees meeting federally defined poverty levels. The authors describe the project and its outcomes, which surpassed original expectations. PMID:18403992

  10. Grouped actinide separation in advanced nuclear fuel cycles

    SciTech Connect

    Glatz, J.P.; Malmbeck, R.; Ougier, M.; Soucek, P.; Murakamin, T.; Tsukada, T.; Koyama, T.

    2013-07-01

    Aiming at cleaner waste streams (containing only the short-lived fission products) a partitioning and transmutation (P-T) scheme can significantly reduce the quantities of long-lived radionuclides consigned to waste. Many issues and options are being discussed and studied at present in view of selecting the optimal route. The choice is between individual treatment of the relevant elements and a grouped treatment of all actinides together. In the European Collaborative Project ACSEPT (Actinide recycling by Separation and Transmutation), grouped separation options derived from an aqueous extraction or from a dry pyroprocessing route were extensively investigated. Successful demonstration tests for both systems have been carried out in the frame of this project. The aqueous process called GANEX (Grouped Actinide Extraction) is composed of 2 cycles, a first one to recover the major part of U followed by a co-extraction of Np, Pu, Am, and Cm altogether. The pyro-reprocessing primarily applicable to metallic fuels such as the U-Pu-Zr alloy originally developed by the Argonne National Laboratory (US) in the mid 1980s, has also been applied to the METAPHIX fuels containing up to 5% of minor actinides and 5% of lanthanides (e.g. U{sub 60}Pu{sub 20}-Zr{sub 10}Am{sub 2}Nd{sub 3.5}Y{sub 0.5}Ce{sub 0.5}Gd{sub 0.5}). A grouped actinide separation has been successfully carried out by electrorefining on solid Al cathodes. At present the recovery of the actinides from the alloy formed with Al upon electrodeposition is under investigation, because an efficient P-T cycle requires multiple re-fabrication and re-irradiation. (authors)

  11. Advancements in the development of a directional-position sensing fast neutron detector using acoustically tensioned metastable fluids

    NASA Astrophysics Data System (ADS)

    Archambault, Brian C.; Webster, Jeffrey A.; Grimes, Thomas F.; Fischer, Kevin F.; Hagen, Alex R.; Taleyakhan, Rusi P.

    2015-06-01

    Advancements in the development of a direction and position sensing fast neutron detector which utilizes the directional acoustic tensioned metastable fluid detector (D-ATMFD) are described. The resulting D-ATMFD sensor is capable of determining the direction of neutron radiation with a single compact detector versus use of arrays of detectors in conventional directional systems. Directional neutron detection and source positioning offer enhanced detection speeds in comparison to traditional proximity searching; including enabling determination of the neutron source shape, size, and strength in near real time. This paper discusses advancements that provide the accuracy and precision of ascertaining directionality and source localization information utilizing enhanced signal processing-cum-signal analysis, refined computational algorithms, and on-demand enlargement capability of the detector sensitive volume. These advancements were accomplished utilizing experimentation and theoretical modeling. Benchmarking and qualifications studies were successfully conducted with random and fission based special nuclear material (SNM) neutron sources (239Pu-Be and 252Cf). These results of assessments have indicated that the D-ATMFD compares well in technical performance with banks of competing directional fast neutron detector technologies under development worldwide, but it does so with a single detector unit, an unlimited field of view, and at a significant reduction in both cost and size while remaining completely blind to common background (e.g., beta-gamma) radiation. Rapid and direct SNM neutron source imaging with two D-ATMFD sensors was experimentally demonstrated, and furthermore, validated via multidimensional nuclear particle transport simulations utilizing MCNP-PoliMi. Characterization of a scaled D-ATMFD based radiation portal monitor (RPM) as a cost-effective and efficient 3He sensor replacement was performed utilizing MCNP-PoliMi simulations, the results of which

  12. Aspects of suspension design for the development of advanced gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Kumar, Rahul

    The Institute for Gravitational Research in the University of Glasgow in collaboration with the Albert Einstein Institute in Hannover, Golm and the University of Cardiff has been actively involved in the research for the development of instruments and data analysis techniques to detect gravitational waves. This includes construction of a long ground based interferometer in Germany called GEO 600 (upgraded to GEO-HF) having an arm length 600 m and strong involvement in the larger detectors of the LIGO (Laser interferometer gravitational wave observatory) project in USA having arm lengths of 4 km (Operated by MIT, Boston and CALTECH, Pasadena). An upgrade to LIGO called Advanced LIGO (aLIGO) is currently under construction with significant input from the University of Glasgow. Thermal noise is one of the most significant noise sources affecting the sensitivity of the detector at a range of frequencies. Thermal noise arises due to the random fluctuations of atoms and molecules in the materials of the test mass mirrors and suspension elements, and is related to mechanical loss in these materials. The work presented in chapter 3 of this thesis is devoted to the analysis of aspects of mechanical loss and thermal noise in the final stages of the GEO suspension. The work in chapter 4 focuses on the theory of photoelasticty and birefringence techniques. A study of mechanical and thermal stress induced in fused silica has been discussed in chapter 5 of this thesis. To understand the working of photoelastic techniques learned in chapter 4, a study of mechanical stress was undertaken by applying a load on the sample to induce temporary birefringence. A study of thermal stress in fused silica welds has also been presented in chapter 5.

  13. Summer Support of the Advanced Structures and Measurements Group

    NASA Technical Reports Server (NTRS)

    Stuber, Alexander Lee

    2010-01-01

    This presentation is my exit presentation summarizing the work that I did this summer during my 10 week summer internship. It is primarily focused on tensile testing of composite coupons including the use of the ARAMIS optical strain measurement system, but it also includes some discussion of other support that I provided for the Dryden composites working group effort. My main efforts in that area were focused on T-joint design for an upcoming hands-on-workshop as well as design of a fixture to test joint coupons. Finally, there is a brief discussion of the other small projects that I worked on, including support of structurally integrated thermal protection system (STIPS) research and the Global Observer wing loads test.

  14. Quantum Well and Quantum Dot Modeling for Advanced Infrared Detectors and Focal Plane Arrays

    NASA Technical Reports Server (NTRS)

    Ting, David; Gunapala, S. D.; Bandara, S. V.; Hill, C. J.

    2006-01-01

    This viewgraph presentation reviews the modeling of Quantum Well Infrared Detectors (QWIP) and Quantum Dot Infrared Detectors (QDIP) in the development of Focal Plane Arrays (FPA). The QWIP Detector being developed is a dual band detector. It is capable of running on two bands Long-Wave Infrared (LWIR) and Medium Wavelength Infrared (MWIR). The same large-format dual-band FPA technology can be applied to Quantum Dot Infrared Photodetector (QDIP) with no modification, once QDIP exceeds QWIP in single device performance. Details of the devices are reviewed.

  15. Investigation of a solid-state detector for advanced computed tomography.

    PubMed

    Hsieh, J; Gurmen, O E; King, K F

    2000-09-01

    Utilization of solid-state detectors for computed tomography (CT) has been the focus of many studies. Previous phantom and clinical experiments have shown that one of the important performance parameters for the solid-state detector is the primary speed and afterglow. In this paper, we present a detailed investigation on the signal decay characteristics of the HiLight (GE Medical Systems, Milwaukee, WI) scintillating detector. The detector primary speed and afterglow are modeled by a multiexponential function and fully characterized by a set of time constants and relative strengths. The sensitivity of these parameters to X-ray photon energy, detector aging, and radiation exposure is then established and analyzed. No statistically significant variation is observed in these parameters due to changes in the above external variables. The impact of various decay time constants on CT image quality, such as spatial resolution, noise, and artifacts, is subsequently illustrated with computer simulations and phantom experiments. Finally, an algorithmic correction scheme is derived to compensate for detector afterglow. The correction scheme employs a recursive filter to remove adverse effects of the detector decay on image quality. Experimental results have shown that the correction scheme successfully restores system spatial resolution, produces a more homogeneous noise pattern, and eliminates ring-band image artifacts due to detector afterglow. The effectiveness and robustness of the correction scheme are demonstrated by extensive phantom and clinical experiments. PMID:11127606

  16. Advanced technologies for future ground-based, laser-interferometric gravitational wave detectors

    PubMed Central

    Hammond, Giles; Hild, Stefan; Pitkin, Matthew

    2014-01-01

    We present a review of modern optical techniques being used and developed for the field of gravitational wave detection. We describe the current state-of-the-art of gravitational waves detector technologies with regard to optical layouts, suspensions and test masses. We discuss the dominant sources and noise in each of these subsystems and the developments that will help mitigate them for future generations of detectors. We very briefly summarise some of the novel astrophysics that will be possible with these upgraded detectors. PMID:25705087

  17. Recent developments in semiconductor gamma-ray detectors

    SciTech Connect

    Luke, Paul N.; Amman, Mark; Tindall, Craig; Lee, Julie S.

    2003-10-28

    The successful development of lithium-drifted Ge detectors in the 1960's marked the beginning of the significant use of semiconductor crystals for direct detection and spectroscopy of gamma rays. In the 1970's, high-purity Ge became available, which enabled the production of complex detectors and multi-detector systems. In the following decades, the technology of semiconductor gamma-ray detectors continued to advance, with significant developments not only in Ge detectors but also in Si detectors and room-temperature compound-semiconductor detectors. In recent years, our group at Lawrence Berkeley National Laboratory has developed a variety of gamma ray detectors based on these semiconductor materials. Examples include Ge strip detectors, lithium-drifted Si strip detectors, and coplanar-grid CdZnTe detectors. These advances provide new capabilities in the measurement of gamma rays, such as the ability to perform imaging and the realization of highly compact spectroscopy systems.

  18. Gravitational waves from Scorpius X-1: A comparison of search methods and prospects for detection with advanced detectors

    NASA Astrophysics Data System (ADS)

    Messenger, C.; Bulten, H. J.; Crowder, S. G.; Dergachev, V.; Galloway, D. K.; Goetz, E.; Jonker, R. J. G.; Lasky, P. D.; Meadors, G. D.; Melatos, A.; Premachandra, S.; Riles, K.; Sammut, L.; Thrane, E. H.; Whelan, J. T.; Zhang, Y.

    2015-07-01

    The low-mass X-ray binary Scorpius X-1 (Sco X-1) is potentially the most luminous source of continuous gravitational-wave radiation for interferometers such as LIGO and Virgo. For low-mass X-ray binaries this radiation would be sustained by active accretion of matter from its binary companion. With the Advanced Detector Era fast approaching, work is underway to develop an array of robust tools for maximizing the science and detection potential of Sco X-1. We describe the plans and progress of a project designed to compare the numerous independent search algorithms currently available. We employ a mock-data challenge in which the search pipelines are tested for their relative proficiencies in parameter estimation, computational efficiency, robustness, and most importantly, search sensitivity. The mock-data challenge data contains an ensemble of 50 Scorpius X-1 (Sco X-1) type signals, simulated within a frequency band of 50-1500 Hz. Simulated detector noise was generated assuming the expected best strain sensitivity of Advanced LIGO [1] and Advanced VIRGO [2] (4 ×10-24 Hz-1 /2 ). A distribution of signal amplitudes was then chosen so as to allow a useful comparison of search methodologies. A factor of 2 in strain separates the quietest detected signal, at 6.8 ×10-26 strain, from the torque-balance limit at a spin frequency of 300 Hz, although this limit could range from 1.2 ×10-25 (25 Hz) to 2.2 ×10-26 (750 Hz) depending on the unknown frequency of Sco X-1. With future improvements to the search algorithms and using advanced detector data, our expectations for probing below the theoretical torque-balance strain limit are optimistic.

  19. Advanced far infrared blocked impurity band detectors based on germanium liquid phase epitaxy

    SciTech Connect

    Olsen, C S

    1998-05-01

    This research has shown that epilayers with residual impurity concentrations of 5 x 10{sup 13} cm{sup {minus}3} can be grown by producing the purest Pb available in the world. These epilayers have extremely low minority acceptor concentrations, which is ideal for fabrication of IR absorbing layers. The Pb LPE growth of Ge also has the advantageous property of gettering Cu from the epilayer and the substrate. Epilayers have been grown with intentional Sb doping for IR absorption on lightly doped substrates. This research has proven that properly working Ge BIB detectors can be fabricated from the liquid phase as long as pure enough solvents are available. The detectors have responded at proper wavelengths when reversed biased even though the response did not quite reach minimum wavenumbers. Optimization of the Sb doping concentration should further decrease the photoionization energy of these detectors. Ge BIB detectors have been fabricated that respond to 60 cm{sup {minus}1} with low responsivity. Through reduction of the minority residual impurities, detector performance has reached responsivities of 1 A/W. These detectors have exhibited quantum efficiency and NEP values that rival conventional photoconductors and are expected to provide a much more sensitive tool for new scientific discoveries in a number of fields, including solid state studies, astronomy, and cosmology.

  20. Advanced far infrared blocked impurity band detectors based on germanium liquid phase epitaxy

    NASA Technical Reports Server (NTRS)

    Olsen, C. S.

    1998-01-01

    This research has shown that epilayers with residual impurity concentrations of 5 x 10(sup 13) cm(exp -3) can be grown by producing the purest Pb available in the world. These epilayers have extremely low minority acceptor concentrations, which is ideal for fabrication of IR absorbing layers. The Pb LPE growth of Ge also has the advantageous property of gettering Cu from the epilayer and the substrate. Epilayers have been grown with intentional Sb doping for IR absorption on lightly doped substrates. This research has proven that properly working Ge BIB detectors can be fabricated from the liquid phase as long as pure enough solvents are available. The detectors have responded at reach minimum wavenumbers. Optimization of the Sb doping concentration should further decrease the photoionization energy of these detectors. Ge BIB detectors have been fabricated that respond to 60 cm(exp -1) with low responsivity. Through reduction of the minority residual impurities, detector performance has reached responsivities of 1 A/W. These detectors have exhibited quantum efficiency and NEP values that rival conventional photoconductors and are expected to provide a much more sensitive tool for new scientific discoveries in a number of fields, including solid state studies, astronomy, and cosmology.

  1. The Science Advancement through Group Engagement Program: Leveling the Playing Field and Increasing Retention in Science

    ERIC Educational Resources Information Center

    Hall, Donna M.; Curtin-Soydan, Amanda J.; Canelas, Dorian A.

    2014-01-01

    How can colleges and universities keep an open gateway to the science disciplines for the least experienced first-year science students while also maintaining high standards that challenge the students with the strongest possible high school backgrounds? The Science Advancement through Group Engagement (SAGE) project targets cohorts of less…

  2. Advanced numerical modeling and hybridization techniques for third-generation infrared detector pixel arrays

    NASA Astrophysics Data System (ADS)

    Schuster, Jonathan

    Infrared (IR) detectors are well established as a vital sensor technology for military, defense and commercial applications. Due to the expense and effort required to fabricate pixel arrays, it is imperative to develop numerical simulation models to perform predictive device simulations which assess device characteristics and design considerations. Towards this end, we have developed a robust three-dimensional (3D) numerical simulation model for IR detector pixel arrays. We used the finite-difference time-domain technique to compute the optical characteristics including the reflectance and the carrier generation rate in the device. Subsequently, we employ the finite element method to solve the drift-diffusion equations to compute the electrical characteristics including the I(V) characteristics, quantum efficiency, crosstalk and modulation transfer function. We use our 3D numerical model to study a new class of detector based on the nBn-architecture. This detector is a unipolar unity-gain barrier device consisting of a narrow-gap absorber layer, a wide-gap barrier layer, and a narrow-gap collector layer. We use our model to study the underlying physics of these devices and to explain the anomalously long lateral collection lengths for photocarriers measured experimentally. Next, we investigate the crosstalk in HgCdTe photovoltaic pixel arrays employing a photon-trapping (PT) structure realized with a periodic array of pillars intended to provide broadband operation. The PT region drastically reduces the crosstalk; making the use of the PT structures not only useful to obtain broadband operation, but also desirable for reducing crosstalk, especially in small pitch detector arrays. Then, the power and flexibility of the nBn architecture is coupled with a PT structure to engineer spectrally filtering detectors. Last, we developed a technique to reduce the cost of large-format, high performance HgCdTe detectors by nondestructively screen-testing detector arrays prior

  3. Recent advances in the modulation transfer function testing of detector arrays

    NASA Astrophysics Data System (ADS)

    Ducharme, Alfred D.

    2008-08-01

    The increased complexity of imaging sensors and total number of discrete detector sites has challenged traditional testing methods. The importance of reliable modulation transfer function testing of imaging sensors with high uncertainty has consequently grown more difficult. In this paper we demonstrate the design of an aperture for the generation of laser speckle with a flat power spectrum covering a wide-band of the measurement spatial frequency range. This aperture allows for the measurement of modulation transfer function (MTF) from zero to twice the Nyquist frequency of a twodimensional detector array. This design mitigates many of the measurement issues inherent in other aperture designs. The MTF measurement of a charge-coupled device (CCD) detector array is used to demonstrate the measurement technique and illustrate the advantages of the new aperture design.

  4. Symmetrical Josephson vortex interferometer as an advanced ballistic single-shot detector

    SciTech Connect

    Soloviev, I. I.; Klenov, N. V.; Bakurskiy, S. V.; Pankratov, A. L.; Kuzmin, L. S.

    2014-11-17

    We consider a ballistic detector formed in an interferometer manner which operational principle relies on Josephson vortex scattering at a measurement potential. We propose an approach to symmetrize the detector scheme and explore arising advantages in the signal-to-noise ratio and in the back-action on a measured object by means of recently presented numerical and analytical methods for modeling of a soliton scattering dynamics in the presence of thermal fluctuations. The obtained characteristics for experimentally relevant parameters reveal practical applicability of the considered schemes including possibility of coupling with standard digital rapid single flux quantum circuits.

  5. Collider Detector at Fermilab (CDF): Data from W, Z bosons and Drell Yan lepton pairs research of the CDF Electroweak Group

    DOE Data Explorer

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group at Fermilab is organized into six working groups, each with a specific focus. The Electroweak group studies production and properties of W, Z bosons and Drell Yan lepton pairs. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  6. Recent advances in superconducting nanowire single photon detectors for single-photon imaging

    NASA Astrophysics Data System (ADS)

    Verma, V. B.; Allman, M. S.; Stevens, M.; Gerrits, T.; Horansky, R. D.; Lita, A. E.; Marsili, F.; Beyer, A.; Shaw, M. D.; Stern, J. A.; Mirin, R. P.; Nam, S. W.

    2016-05-01

    We demonstrate a 64-pixel free-space-coupled array of superconducting nanowire single photon detectors optimized for high detection efficiency in the near-infrared range. An integrated, readily scalable, multiplexed readout scheme is employed to reduce the number of readout lines to 16. The cryogenic, optical, and electronic packaging to read out the array, as well as characterization measurements are discussed.

  7. AIDA: A 16-channel amplifier ASIC to read out the advanced implantation detector array for experiments in nuclear decay spectroscopy

    SciTech Connect

    Braga, D.; Coleman-Smith, P. J.; Davinson, T.; Lazarus, I. H.; Page, R. D.; Thomas, S.

    2011-07-01

    We have designed a read-out ASIC for nuclear decay spectroscopy as part of the AIDA project - the Advanced Implantation Detector Array. AIDA will be installed in experiments at the Facility for Antiproton and Ion Research in GSI, Darmstadt. The AIDA ASIC will measure the signals when unstable nuclei are implanted into the detector, followed by the much smaller signals when the nuclei subsequently decay. Implant energies can be as high as 20 GeV; decay products need to be measured down to 25 keV within just a few microseconds of the initial implants. The ASIC uses two amplifiers per detector channel, one covering the 20 GeV dynamic range, the other selectable over a 20 MeV or 1 GeV range. The amplifiers are linked together by bypass transistors which are normally switched off. The arrival of a large signal causes saturation of the low-energy amplifier and a fluctuation of the input voltage, which activates the link to the high-energy amplifier. The bypass transistors switch on and the input charge is integrated by the high-energy amplifier. The signal is shaped and stored by a peak-hold, then read out on a multiplexed output. Control logic resets the amplifiers and bypass circuit, allowing the low-energy amplifier to measure the subsequent decay signal. We present simulations and test results, demonstrating the AIDA ASIC operation over a wide range of input signals. (authors)

  8. InAs/GaSb type II superlattices for advanced 2nd and 3rd generation detectors

    NASA Astrophysics Data System (ADS)

    Walther, Martin; Rehm, Robert; Schmitz, Johannes; Fleissner, Joachim; Rutz, Frank; Kirste, Lutz; Scheibner, Ralf; Wendler, Joachim; Ziegler, Johann

    2010-01-01

    InAs/GaSb short-period superlattices (SL) based on GaSb, InAs and AlSb have proven their great potential for high performance infrared detectors. Lots of interest is currently focused on the development of short-period InAs/GaSb SLs for advanced 2nd and 3rd generation infrared detectors between 3 - 30 μm. For the fabrication of mono- and bispectral thermal imaging systems in the mid-wavelength infrared region (MWIR) a manufacturable technology for high responsivity thermal imaging systems has been developed. InAs/GaSb short-period superlattices can be fabricated with up to 1000 periods in the intrinsic region without revealing diffusion limited behavior. This enables the fabrication of InAs/GaSb SL camera systems with high responsivity comparable to state of the art CdHgTe and InSb detectors. The material system is also ideally suited for the fabrication of dual-color MWIR/MWIR InAs/GaSb SL camera systems with high quantum efficiency for missile approach warning systems with simultaneous and spatially coincident detection in both spectral channels.

  9. Patients Presenting with Advanced Human Immunodeficiency Virus Disease: Epidemiological Features by Age Group

    PubMed Central

    2016-01-01

    We explored factors influencing presentation with advanced human immunodeficiency virus (HIV) disease by age group. Data were derived from a city-wide cross-sectional survey of 759 HIV-infected adults living in Seoul, Korea. The significance of each observed factor was assessed via multivariate logistic regression. Of subjects aged 20-34 years, lower educational level had a positive influence on presentation with advanced HIV disease (adjusted odds ratio [aOR], 2.43; 95% confidence interval [CI], 1.36-4.34); those recently diagnosed with HIV were more likely to be presented with advanced HIV disease (aOR, 3.17; 95% CI, 0.99-10.2). Of the subjects aged 35-49 years, those w ith advanced HIV disease were more likely to have been diagnosed during health check-ups (aOR, 2.91; 95% CI, 1.15-7.32) or via clinical manifestations (aOR, 3.61; 95% CI, 1.39-9.36). Of the subjects aged ≥ 50 years, presentation with advanced HIV disease was significantly more common in older subjects (aOR per increment of 5 years, 2.06; 95% CI, 1.32-3.23) and less common among individuals diagnosed with HIV in 2000-2006 (aOR, 0.18; 95% CI, 0.04-0.83). In conclusion, a lower educational level in younger subjects and more advanced age in older subjects positively influence the presentation of advanced HIV disease. PMID:26839469

  10. Growth of detector-grade CZT by Traveling Heater Method (THM): An advancement

    SciTech Connect

    ROY, U.N.; JAMES, R.; WEILER, S.; STEIN, J.; GROZA, M.; BURGER, A.; BOLOTNIKOV, A.E.; CAMARDA, G.S.; HOSSAIN, A.; YANG, G.

    2011-04-25

    In this present work we report the growth of Cd{sub 0.9}Zn{sub 0.1}Te doped with In by a modified THM technique. It has been demonstrated that by controlling the microscopically flat growth interface, the size distribution and concentration can be drastically reduced in the as-grown ingots. This results in as-grown detector-grade CZT by the THM technique. The three-dimensional size distribution and concentrations of Te inclusions/precipitations were studied. The size distributions of the Te precipitations/inclusions were observed to be below the 10-{micro}m range with the total concentration less than 10{sup 5} cm{sup -3}. The relatively low value of Te inclusions/precipitations results in excellent charge transport properties of our as-grown samples. The ({mu}{tau}){sub e} values for different as-grown samples varied between 6-20 x 10{sup -3} cm{sup 2}/V. The as-grown samples also showed fairly good detector response with resolution of {approx}1.5%, 2.7% and about 3.8% at 662 keV for quasi-hemispherical geometry for detector volumes of 0.18 cm{sup 3}, 1 cm{sup 3} and 4.2 cm{sup 3}, respectively.

  11. Advances in CMOS Solid-state Photomultipliers for Scintillation Detector Applications

    PubMed Central

    Christian, James F.; Stapels, Christopher J.; Johnson, Erik B.; McClish, Mickel; Dokhale, Purushotthom; Shah, Kanai S.; Mukhopadhyay, Sharmistha; Chapman, Eric; Augustine, Frank L.

    2014-01-01

    Solid-state photomultipliers (SSPMs) are a compact, lightweight, potentially low-cost alternative to a photomultiplier tube for a variety of scintillation detector applications, including digital-dosimeter and medical-imaging applications. Manufacturing SSPMs with a commercial CMOS process provides the ability for rapid prototyping, and facilitates production to reduce the cost. RMD designs CMOS SSPM devices that are fabricated by commercial foundries. This work describes the characterization and performance of these devices for scintillation detector applications. This work also describes the terms contributing to device noise in terms of the excess noise of the SSPM, the binomial statistics governing the number of pixels triggered by a scintillation event, and the background, or thermal, count rate. The fluctuations associated with these terms limit the resolution of the signal pulse amplitude. We explore the use of pixel-level signal conditioning, and characterize the performance of a prototype SSPM device that preserves the digital nature of the signal. In addition, we explore designs of position-sensitive SSPM detectors for medical imaging applications, and characterize their performance. PMID:25540471

  12. Advanced data readout technique for Multianode Position Sensitive Photomultiplier Tube applicable in radiation imaging detectors

    SciTech Connect

    V. Popov

    2011-01-01

    Most of the best performing PSPMT tubes from Hamamatsu and Burle are designed with a pad-matrix anode layout. However, for obtaining a high resolution, a small-sized anode photomultiplier tubes are preferable; these tubes may have 64, 256 or 1024 anodes per tube. If the tubes are used in array to get a larger area detector, the number of analog channels may range from hundreds to thousands. Multichannel analog readout requires special electronics ICs, ASICs etc., which are attached to multichannel DAQ system. As a result, the data file and data processing time will be increased. Therefore, this readout could not be performed in a small project. Usually, most of radiation imaging applications allow the use of analog data processing in front-end electronics, significantly reducing the number of the detector's output lines to data acquisition without reducing the image quality. The idea of pad-matrix decoupling circuit with gain correction was invented and intensively tested in JLab. Several versions of PSPMT readout electronics were produced and studied. All developments were done and optimized specifically for radiation imaging projects. They covered high resolution SPECT, high speed PET, fast neutron imaging, and single tube and multi tube array systems. This paper presents and discusses the summary of the observed results in readout electronics evaluation with different PSPMTs and radiation imaging systems, as well as the advantages and limitations of the developed approach to radiation imaging detectors readout.

  13. Oversampling advances in millimeter-wave scan imaging using inexpensive neon indicator lamp detectors

    NASA Astrophysics Data System (ADS)

    Levanon, Assaf; Kopeika, Natan S.; Yitzhaky, Yitzhak; Abramovich, Amir; Rozban, Daniel; Joseph, Hezi; Aharon, Avihai; Belenky, Alex; Gefen, Michael; Yadid-Pecht, Orly

    2013-06-01

    In recent years, much effort has been invested to develop room temperature inexpensive, but sensitive, millimeter wave (MMW) and terahertz (THz) detectors that can be used as pixels in focal plane arrays, which is important for real-time imaging. A new 18×2 neon indicator lamp MMW/THz scanner was developed. The components of the camera include horizontally shifted two-column glow discharge detectors in a scanning array. The detectors, costing about 50 cents each, are wired to a preprocessing card, a VLSI board, and a motor for scanner movement. A description of the VLSI Verilog programmable hardware of the new scanner, the physical architecture, the software user interface, and imaging results at 97 GHz are presented. At this stage, the emphasis is focused on the lamp exposure time and spatial resolution when the scanning is performed horizontally. In the future it is planned to expose all pixels simultaneously for real-time imaging. New software capabilities allow the application of digital image enhancement algorithms. Fast scanning permits obtaining images in 1 to 5 s. Oversampling yields a sharper edge response and a higher signal-to-noise ratio.

  14. Advanced Photon Counting Imaging Detectors with 100ps Timing for Astronomical and Space Sensing Applications

    NASA Astrophysics Data System (ADS)

    Siegmund, O.; Vallerga, J.; Welsh, B.; Rabin, M.; Bloch, J.

    In recent years EAG has implemented a variety of high-resolution, large format, photon-counting MCP detectors in space instrumentation for satellite FUSE, GALEX, IMAGE, SOHO, HST-COS, rocket, and shuttle payloads. Our scheme of choice has been delay line readouts encoding photon event position centroids, by determination of the difference in arrival time of the event charge at the two ends of a distributed resistive-capacitive (RC) delay line. Our most commonly used delay line configuration is the cross delay line (XDL). In its simplest form the delay-line encoding electronics consists of a fast amplifier for each end of the delay line, followed by time-to-digital converters (TDC's). We have achieved resolutions of < 25 μm in tests over 65 mm x 65 mm (3k x3k resolution elements) with excellent linearity. Using high speed TDC's, we have been able to encode event positions for random photon rates of ~1 MHz, while time tagging events using the MCP output signal to better than 100 ps. The unique ability to record photon X,Y,T high fidelity information has advantages over "frame driven" recording devices for some important applications. For example we have built open face and sealed tube cross delay line detectors used for biological fluorescence lifetime imaging, observation of flare stars, orbital satellites and space debris with the GALEX satellite, and time resolved imaging of the Crab Pulsar with a telescope as small as 1m. Although microchannel plate delay line detectors meet many of the imaging and timing demands of various applications, they have limitations. The relatively high gain (107) reduces lifetime and local counting rate, and the fixed delay (10's of ns) makes multiple simultaneous event recording problematic. To overcome these limitations we have begun development of cross strip readout anodes for microchannel plate detectors. The cross strip (XS) anode is a coarse (~0.5 mm) multi-layer metal and ceramic pattern of crossed fingers on an alumina

  15. Use of Protecting Groups in Carbohydrate Chemistry: An Advanced Organic Synthesis Experiment

    NASA Astrophysics Data System (ADS)

    Cunha, Anna C.; Pereira, Leticia O. R.; de Souza, Maria Cecília B. V.; Ferreira, Vitor F.

    1999-01-01

    A simple and inexpensive three-step reaction sequence for advanced experimental organic chemistry using D-glucosamine hydrochloride as starting material for the synthesis of 2-amino-2-deoxy-1,3,4,6-tetra-O-acetyl-b-D-glucopyranose hydrochloride is described. D-Glucosamine hydrochloride is a carbohydrate derivative isolated from crab shells. It is inexpensive and readily available from most chemical companies. This reaction sequence is appropriate for teaching undergraduate students the correct use of protecting groups. This is a major concept in organic synthesis and one of the determinant factors in the successful realization of multiple-step synthetic projects. The aim of the experiment is to protect the hydroxyl groups of D-glucosamine leaving its amino group as hydrochloride salt. The experiment deals only with protection and deprotection reactions. All products are crystalline substances. The amino group of d-glucosamine hydrochloride is protected by a condensation reaction with p-methoxybenzaldehyde to produce the Schiff's base as a mixture of a- and b-anomers. The second step involves the protection of all hydroxyl groups by esterification reaction using acetic anhydride, forming the imino-tetraacetate derivative as the b-anomer. The stereospecificity of this reaction at the anomeric center is due to the voluminous imino group at C-2. Removal of the amino protection group of this derivative is the final step, which can be accomplished by a selective acid hydrolysis affording the desired peracylated D-glucosamine hydrochloride.

  16. Lunar Seismic Detector to Advance the Search for Strange Quark Matter

    NASA Technical Reports Server (NTRS)

    Galitzki, Nicholas B.

    2005-01-01

    Detection of small seismic signals on the Moon are needed to study lunar internal structure and to detect possible signals from Strange Quark m&er transit events. The immediate objective is to create a prototype seismic detector using a tunnel diode oscillator with a variable capacitor attached to a proof mass. The device is designed to operate effectively on the Moon, which requires a low power consumption to operate through lunar night, while preserving sensitivity. The goal is capacitance resolution of better than 1 part in 10' and power consumption of less than 1 watt.

  17. Impact of upconverted scattered light on advanced interferometric gravitational wave detectors.

    PubMed

    Ottaway, David J; Fritschel, Peter; Waldman, Samuel J

    2012-04-01

    Second generation gravitational wave detectors are being installed in a number of locations globally. These long-baseline, Michelson interferometers increase the sensitivity between 10 and 40 Hz by many orders of magnitude compared with first generation instruments. Control of non-linear noise coupling from scattered light fields is critical to achieve low frequency performance. In this paper we investigate the requirements on the attenuation of scattered light using a novel time-domain analysis and two years of seismic data from the LIGO Livingston Observatory. PMID:22513544

  18. Combinatorial Screening of Advanced Scintillators for High Resolution X-ray Detectors

    SciTech Connect

    Cheng, Shifan; Tao, Dejie; Lynch, Michael; Yuan, Xianglong; Li, Yiqun

    2008-05-12

    The lack of efficient scintillators is a major problem for developing powerful x-ray detectors that are widely used in homeland security, industrial and scientific research. Intematix has developed and applied a high throughput screening process and corresponding crystal growth technology to significantly speed up the discovery process for new efficient scintillators. As a result, Intematix has invented and fabricated three new scintillators both in powder and bulk forms, which possess promising properties such as better radiation hardness and better matching for silicon diode.

  19. Displacement noise from back scattering and specular reflection of input optics in advanced gravitational wave detectors.

    PubMed

    Canuel, B; Genin, E; Vajente, G; Marque, J

    2013-05-01

    The second generation of ground-based interferometric gravitational wave detectors are currently being built and installed. They are designed to be better in strain sensitivity by about a factor 10 with respect to the first generation. Light originating from the laser and following unintended paths, called stray light, has been a major problem during the commissioning of all of the first generation detectors. Indeed, stray light carries information about the phase of the emitting object. Therefore, in the next generation all the optics will be suspended in the vacuum in order to mitigate their associated stray light displacement noise. Despite this additional precaution, the challenging target sensitivity at low frequency which is partially limited by quantum radiation pressure combined with up-conversion effects, requires more detailed investigation. In this paper, we turn our attention to stray light originating from auxiliary optical benches. We use a dedicated formalism to compute the re-coupling of back-reflected and back-scattered light. We show, in particular, how much care should be taken in designing and setting requirements for the input bench optics. PMID:23669911

  20. Advances Towards Readily Deployable Antineutrino Detectors for Reactor Monitoring and Safeguards

    SciTech Connect

    Bowden, N S; Bernstein, A; Dazeley, S; Lund, J; Reyna, D; Sadler, L; Svoboda, R

    2008-06-05

    Nuclear reactors have served as the neutrino source for many fundamental physics experiments. The techniques developed by these experiments make it possible to use these very weakly interacting particles for a practical purpose. The large flux of antineutrinos that leaves a reactor carries information about two quantities of interest for safeguards: the reactor power and fissile inventory. Our LLNL/SNL collaboration has demonstrated that such antineutrino based monitoring is feasible using a relatively small cubic meter scale detector at tens of meters standoff from a commercial PWR. With little or no burden on the plant operator we have been able to remotely and automatically monitor the reactor operational status (on/off), power level, and fuel burnup. Recently, we have investigated several technology paths that could allow such devices to be more readily deployed in the field. In particular, we have developed and fielded two new detectors; a low cost, non- flammable water based design; and a robust solid-state design based upon plastic scintillator. Here we will describe the tradeoffs inherent in these designs, and present results from their field deployments.

  1. Fire Detector

    NASA Technical Reports Server (NTRS)

    1978-01-01

    An early warning fire detection sensor developed for NASA's Space Shuttle Orbiter is being evaluated as a possible hazard prevention system for mining operations. The incipient Fire Detector represents an advancement over commercially available smoke detectors in that it senses and signals the presence of a fire condition before the appearance of flame and smoke, offering an extra margin of safety.

  2. The Urey Instrument: An Advanced In Situ Organic and Oxidant Detector for Mars Exploration

    NASA Astrophysics Data System (ADS)

    Aubrey, Andrew D.; Chalmers, John H.; Bada, Jeffrey L.; Grunthaner, Frank J.; Amashukeli, Xenia; Willis, Peter; Skelley, Alison M.; Mathies, Richard A.; Quinn, Richard C.; Zent, Aaron P.; Ehrenfreund, Pascale; Amundson, Ron; Glavin Daniel P.; Botta, Oliver; Barron, Laurence; Blaney, Diana L.; Clark, Benton C.; Coleman, Max; Hofmann, Beda A.; Josset, Jean-Luc; Rettberg, Petra; Ride, Sally; Musée, François Robert; Sephton, Mark A.; Yen, Albert

    2008-06-01

    The Urey organic and oxidant detector consists of a suite of instruments designed to search for several classes of organic molecules in the martian regolith and ascertain whether these compounds were produced by biotic or abiotic processes using chirality measurements. These experiments will also determine the chemical stability of organic molecules within the host regolith based on the presence and chemical reactivity of surface and atmospheric oxidants. Urey has been selected for the Pasteur payload on the European Space Agency's (ESA's) upcoming 2013 ExoMars rover mission. The diverse and effective capabilities of Urey make it an integral part of the payload and will help to achieve a large portion of the mission's primary scientific objective: "to search for signs of past and present life on Mars." This instrument is named in honor of Harold Urey for his seminal contributions to the fields of cosmochemistry and the origin of life.

  3. The Urey instrument: an advanced in situ organic and oxidant detector for Mars exploration.

    PubMed

    Aubrey, Andrew D; Chalmers, John H; Bada, Jeffrey L; Grunthaner, Frank J; Amashukeli, Xenia; Willis, Peter; Skelley, Alison M; Mathies, Richard A; Quinn, Richard C; Zent, Aaron P; Ehrenfreund, Pascale; Amundson, Ron; Glavin, Daniel P; Botta, Oliver; Barron, Laurence; Blaney, Diana L; Clark, Benton C; Coleman, Max; Hofmann, Beda A; Josset, Jean-Luc; Rettberg, Petra; Ride, Sally; Robert, François; Sephton, Mark A; Yen, Albert

    2008-06-01

    The Urey organic and oxidant detector consists of a suite of instruments designed to search for several classes of organic molecules in the martian regolith and ascertain whether these compounds were produced by biotic or abiotic processes using chirality measurements. These experiments will also determine the chemical stability of organic molecules within the host regolith based on the presence and chemical reactivity of surface and atmospheric oxidants. Urey has been selected for the Pasteur payload on the European Space Agency's (ESA's) upcoming 2013 ExoMars rover mission. The diverse and effective capabilities of Urey make it an integral part of the payload and will help to achieve a large portion of the mission's primary scientific objective: "to search for signs of past and present life on Mars." This instrument is named in honor of Harold Urey for his seminal contributions to the fields of cosmochemistry and the origin of life. PMID:18680409

  4. Overview of the 3rd isirv-Antiviral Group Conference – advances in clinical management

    PubMed Central

    Hurt, Aeron C; Hui, David S; Hay, Alan; Hayden, Frederick G

    2015-01-01

    This review highlights the main points which emerged from the presentations and discussions at the 3rd isirv-Antiviral Group Conference - advances in clinical management. The conference covered emerging and potentially pandemic influenza viruses and discussed novel/pre-licensure therapeutics and currently approved antivirals and vaccines for the control of influenza. Current data on approved and novel treatments for non-influenza respiratory viruses such as MERS-CoV, respiratory syncytial virus (RSV) and rhinoviruses and the challenges of treating immunocompromised patients with respiratory infections was highlighted. PMID:25399715

  5. Coarse-scaling adjustment of fine-group neutron spectra for epithermal neutron beams in BNCT using multiple activation detectors

    NASA Astrophysics Data System (ADS)

    Liu, Yuan-Hao; Nievaart, Sander; Tsai, Pi-En; Liu, Hong-Ming; Moss, Ray; Jiang, Shiang-Huei

    2009-01-01

    In order to provide an improved and reliable neutron source description for treatment planning in boron neutron capture therapy (BNCT), a spectrum adjustment procedure named coarse-scaling adjustment has been developed and applied to the neutron spectrum measurements of both the Tsing Hua Open-pool Reactor (THOR) epithermal neutron beam in Taiwan and the High Flux Reactor (HFR) in The Netherlands, using multiple activation detectors. The coarse-scaling adjustment utilizes a similar idea as the well-known two-foil method, which adjusts the thermal and epithermal neutron fluxes according to the Maxwellian distribution for thermal neutrons and 1/ E distribution over the epithermal neutron energy region. The coarse-scaling adjustment can effectively suppress the number of oscillations appearing in the adjusted spectrum and provide better smoothness. This paper also presents a sophisticated 9-step process utilizing twice the coarse-scaling adjustment which can adjust a given coarse-group spectrum into a fine-group structure, i.e. 640 groups, with satisfactory continuity and excellently matched reaction rates between measurements and calculation. The spectrum adjustment algorithm applied in this study is the same as the well-known SAND-II.

  6. Interagency Advanced Power Group (IAPG) meeting compendium. October 1991--December 1992

    SciTech Connect

    Not Available

    1993-01-01

    Under the direction of the Interagency Advanced Power Group (IAPG), the Power Information Center (PIC) provides support services for each IAPG information exchange session. IAPG members meet a minimum of once each year to share programmatic and technical information on federally funded research and development (R&D) projects in the area of advanced power. This R&D is directed by one of the five IAPG member agencies-the US Army, US Navy, US Air Force, US Department of Energy, and the National Aeronautics and Space Administration. Affiliated Federal groups and federally funded research and development centers can also participate. To enhance the exchange of information between Government researchers, this 1992 IAPG Meeting Compendium has been assembled. This publication is a re-printing of abstracts of each IAPG presentation offered during 1991-1992. The information is arranged chronologically by IAPG meeting. During the 1992 IAPG meeting year, there were presentations restricted to Government audiences only. These ``Restricted`` minutes have not been included in this compilation.

  7. Meaning-centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial

    PubMed Central

    Breitbart, William; Rosenfeld, Barry; Gibson, Christopher; Pessin, Hayley; Poppito, Shannon; Nelson, Christian; Tomarken, Alexis; Timm, Anne Kosinski; Berg, Amy; Jacobson, Colleen; Sorger, Brooke; Abbey, Jennifer; Olden, Megan

    2013-01-01

    Objectives An increasingly important concern for clinicians who care for patients at the end of life is their spiritual well-being and sense of meaning and purpose in life. In response to the need for short-term interventions to address spiritual well-being, we developed Meaning Centered Group Psychotherapy (MCGP) to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose in their lives, even as they approach the end of life. Methods Patients with advanced (stage III or IV) solid tumor cancers (N = 90) were randomly assigned to either MCGP or a supportive group psychotherapy (SGP). Patients were assessed before and after completing the 8-week intervention, and again 2 months after completion. Outcome assessment included measures of spiritual well-being, meaning, hopelessness, desire for death, optimism/pessimism, anxiety, depression and overall quality of life. Results MCGP resulted in significantly greater improvements in spiritual well-being and a sense of meaning. Treatment gains were even more substantial (based on effect size estimates) at the second follow-up assessment. Improvements in anxiety and desire for death were also significant (and increased over time). There was no significant improvement on any of these variables for patients participating in SGP. Conclusions MCGP appears to be a potentially beneficial intervention for patients’ emotional and spiritual suffering at the end of life. Further research, with larger samples, is clearly needed to better understand the potential benefits of this novel intervention. PMID:19274623

  8. An uncooled thermal-array-based detector as an advanced security sensor

    NASA Astrophysics Data System (ADS)

    Rimmer, Andrew N.

    2004-09-01

    A 16x16 un-cooled thermal array based detector (ABD) offers the prospect of a new generation of security sensors, with high false alarm rejection and the ability to detect, track and count the number of intruders. The IRISYS array provides the ability not simply to detect an intruder, but by tracking them as a true moving target discriminate between real and false alarm sources. Target processing is carried out within the sensor allowing the position and size of each target within the field of view to be generated. The location and size for each target is output as a low bandwidth data message suitable for transmission over alarm signalling networks. A central security management system or alarm receiving centre display would provide an operator with an intruder count per room, a pseudo 'visual' display of targets and locations, show target vectors on a graphical display and track targets from room to room, allowing an appropriate response to be initiated. Taking the same concepts into external detection, should allow discrimination of humans versus animals or vermin and afford a high level of reasoning to reject environmentally generated false alarms. In external detection applications using the ABD as a trigger for CCTV, intruder location data would be used to steer and zoom a PTZ camera to achieve an identification view. As auto tracking features are added to the latest dome cameras the ABD's ability to track and output simultaneous data from multiple targets will steer a camera between several intruders.

  9. Systematic development of a group quantification method using evaporative light scattering detector for relative quantification of ginsenosides in ginseng products.

    PubMed

    Lee, Gwang Jin; Shin, Byong-Kyu; Yu, Yun-Hyun; Ahn, Jongsung; Kwon, Sung Won; Park, Jeong Hill

    2016-09-01

    The determination for the contents of multi-components in ginseng products has come to the fore by demands of in-depth information, but the associated industries confront the high cost of securing pure standards for the continuous quality evaluation of the products. This study aimed to develop a prospective high-performance liquid chromatography-evaporative light scattering detector (HPLC-ELSD) method for relative quantification of ginsenosides in ginseng products without a considerable change from the conventional gradient analysis. We investigated the effects of mobile phase composition and elution bandwidth, which are potential variables affecting the ELSD response in the gradient analysis. Similar ELSD response curves of nine major ginsenosides were obtained under the identical flow injection conditions, and the response increased as the percentage of organic solvent increased. The nine ginsenosides were divided into three groups to confirm the effect of elution bandwidth. The ELSD response significantly decreased in case of the late eluted ginsenoside in the individual groups under the isocratic conditions. With the consideration of the two important effects, stepwise changes of the gradient condition were carried out to reach a group quantification method. The inconsistent responses of the nine ginsenosides were reconstituted to three normalized responses by the stepwise changes of the gradient condition, and this result actualized relative quantification in the individual groups. The availability was confirmed by comparing the ginsenoside contents in a base material of ginseng products determined by the direct and group quantification method. The largest difference in the determination results from the two methods was 8.26%, and the difference of total contents was only 0.91%. PMID:27262109

  10. Measuring Intermediate-Mass Black-Hole Binaries with Advanced Gravitational Wave Detectors.

    PubMed

    Veitch, John; Pürrer, Michael; Mandel, Ilya

    2015-10-01

    We perform a systematic study to explore the accuracy with which the parameters of intermediate-mass black-hole binary systems can be measured from their gravitational wave (GW) signatures using second-generation GW detectors. We make use of the most recent reduced-order models containing inspiral, merger, and ringdown signals of aligned-spin effective-one-body waveforms to significantly speed up the calculations. We explore the phenomenology of the measurement accuracies for binaries with total masses between 50M(⊙) and 500M(⊙) and mass ratios between 0.1 and 1. We find that (i) at total masses below ∼200M(⊙), where the signal-to-noise ratio is dominated by the inspiral portion of the signal, the chirp mass parameter can be accurately measured; (ii) at higher masses, the information content is dominated by the ringdown, and total mass is measured more accurately; (iii) the mass of the lower-mass companion is poorly estimated, especially at high total mass and more extreme mass ratios; and (iv) spin cannot be accurately measured for our injection set with nonspinning components. Most importantly, we find that for binaries with nonspinning components at all values of the mass ratio in the considered range and at a network signal-to-noise ratio of 15, analyzed with spin-aligned templates, the presence of an intermediate-mass black hole with mass >100M(⊙) can be confirmed with 95% confidence in any binary that includes a component with a mass of 130M(⊙) or greater. PMID:26551801

  11. Measuring Intermediate-Mass Black-Hole Binaries with Advanced Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    Veitch, John; Pürrer, Michael; Mandel, Ilya

    2015-10-01

    We perform a systematic study to explore the accuracy with which the parameters of intermediate-mass black-hole binary systems can be measured from their gravitational wave (GW) signatures using second-generation GW detectors. We make use of the most recent reduced-order models containing inspiral, merger, and ringdown signals of aligned-spin effective-one-body waveforms to significantly speed up the calculations. We explore the phenomenology of the measurement accuracies for binaries with total masses between 50 M⊙ and 500 M⊙ and mass ratios between 0.1 and 1. We find that (i) at total masses below ˜200 M⊙, where the signal-to-noise ratio is dominated by the inspiral portion of the signal, the chirp mass parameter can be accurately measured; (ii) at higher masses, the information content is dominated by the ringdown, and total mass is measured more accurately; (iii) the mass of the lower-mass companion is poorly estimated, especially at high total mass and more extreme mass ratios; and (iv) spin cannot be accurately measured for our injection set with nonspinning components. Most importantly, we find that for binaries with nonspinning components at all values of the mass ratio in the considered range and at a network signal-to-noise ratio of 15, analyzed with spin-aligned templates, the presence of an intermediate-mass black hole with mass >100 M⊙ can be confirmed with 95% confidence in any binary that includes a component with a mass of 130 M⊙ or greater.

  12. Growth and activation of group IV semiconductors for application in infrared detectors and photovoltaics

    NASA Astrophysics Data System (ADS)

    Xie, Junqi

    Bandgaps in group IV semiconductors such as Ge1-ySn y and Ge1-x-ySixSny are tunable by varying the material composition. The tunable bandgaps make these materials with potential applications in photodetectors, modulators, waveguiders, lasers and photovolatics. This dissertation reports significant improvements of the low-temperature chemical vapor deposition (CVD) process leading to growth of device quality Ge0.98Sn0.02 films with thickness over 500 nm. Highly controlled and efficient doping protocols were also developed to obtain facile substitution and complete activation of dopant atoms at levels 1017 -- 1019 cm-3 via both conventional and custom built molecules. Ge0.98Sn0.02-based PIN structures were subsequently fabricated and characterized. Results show that the incorporation of only 2% of Sn extends the infrared performance of Ge0.98Sn 0.02 based optoelectronic devices to the entire range of transmission windows for telecom applications. Higher Sn content (5% Sn) Ge1-ySny films were also studied to extend the device performance range even further into the infrared. The successful depositions of intrinsic, p- and n-type materials with doping levels 1018-1020/cm3 indicate all components were in place for the fabrication of Ge0.95Sn 0.02-based PIN structures. Meanwhile, a new approach to high quality Ge1-x-ySix Sny ternaries grown directly on both Ge(100) and Si (100) substrates was established based on commercially available sources such as trisilane, digermane and stannane. The soft chemistry process was extended to fabricated p- and n-type layers on Si, and their optical and electrical properties were determined. Characterizations indicate that the properties of GeSiSn are independent of the platform on which they are grown including Si, Ge or GeSn/Si. First-principles calculations show that mixing entropy thermodynamically stabilizes SiGeSn in contrast to GeSn analogs with the same Sn content, in good agreement with experimentally observation. In addition

  13. Advanced composites: Design and application. Proceedings of the meeting of the Mechanical Failures Prevention Group

    NASA Technical Reports Server (NTRS)

    Shives, T. R.; Willard, W. A.

    1979-01-01

    The design and application of advanced composites is discussed with emphasis on aerospace, aircraft, automotive, marine, and industrial applications. Failure modes in advanced composites are also discussed.

  14. 40 CFR 35.4085 - Can my group get an “advance payment” to help us get started?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Can my group get an âadvance paymentâ to help us get started? 35.4085 Section 35.4085 Protection of Environment ENVIRONMENTAL PROTECTION... You Get the Money § 35.4085 Can my group get an “advance payment” to help us get started? Yes,...

  15. 40 CFR 35.4085 - Can my group get an “advance payment” to help us get started?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Can my group get an âadvance paymentâ to help us get started? 35.4085 Section 35.4085 Protection of Environment ENVIRONMENTAL PROTECTION... You Get the Money § 35.4085 Can my group get an “advance payment” to help us get started? Yes,...

  16. 40 CFR 35.4085 - Can my group get an “advance payment” to help us get started?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Can my group get an âadvance paymentâ to help us get started? 35.4085 Section 35.4085 Protection of Environment ENVIRONMENTAL PROTECTION... You Get the Money § 35.4085 Can my group get an “advance payment” to help us get started? Yes,...

  17. 40 CFR 35.4085 - Can my group get an “advance payment” to help us get started?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Can my group get an âadvance paymentâ to help us get started? 35.4085 Section 35.4085 Protection of Environment ENVIRONMENTAL PROTECTION... You Get the Money § 35.4085 Can my group get an “advance payment” to help us get started? Yes,...

  18. 40 CFR 35.4085 - Can my group get an “advance payment” to help us get started?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Can my group get an âadvance paymentâ to help us get started? 35.4085 Section 35.4085 Protection of Environment ENVIRONMENTAL PROTECTION... You Get the Money § 35.4085 Can my group get an “advance payment” to help us get started? Yes,...

  19. Development of a Pharmacy Capstone Course From Focus Groups to Advanced Patient Care

    PubMed Central

    Cooley, Janet H; Tanner, Natalee E; Hanauer, Courtney N; Schiefer, Danielle M; Herrier, Richard N

    2014-01-01

    Objective. To describe the development of a capstone course using qualitative results of focus groups and to determine the impact of the course using a pre- and postcourse surveys. Design. A course titled Advanced Patient Care was developed using themes emerged from 3 stakeholder focus groups and implemented with case-based sessions, interactive exercises, and Objective Structured Clinical Examinations (OSCEs). Pre- and postcourse surveys were conducted to assess the students’ confidence and knowledge in managing 8 commonly-encountered conditions. Assessment. During the 2-year course implementation, a total of 169 students participated in the pre- and postcourse surveys (87.6% response rate). The mean total confidence score increased significantly from 54.3 (±9.2) to 69.0 (±8.6, p<0.001), and the total mean knowledge score increased significantly from 6.3 to 6.9 (p<0.001). Conclusion. The capstone course, fueled by focus group findings and implemented using interactive sessions and simulations, positively impacted students’ confidence and knowledge for clinical practice experiences and professional practice. PMID:25386021

  20. Electron multiplication CCD detector technology advancement for the WFIRST-AFTA coronagraph

    NASA Astrophysics Data System (ADS)

    Harding, Leon K.; Demers, Richard T.; Hoenk, Michael; Peddada, Pavani; Nemati, Bijan; Cherng, Michael; Michaels, Darren; Loc, Anthony; Bush, Nathan; Hall, David; Murray, Neil; Gow, Jason; Burgon, Ross; Holland, Andrew; Reinheimer, Alice; Jorden, Paul R.; Jordan, Douglas

    2015-11-01

    The WFIRST-AFTA (Wide Field InfraRed Survey Telescope-Astrophysics Focused Telescope Asset) is a NASA space observatory. It will host two major astronomical instruments: a wide-field imager (WFI) to search for dark energy and carry out wide field near infrared (NIR) surveys, and a coronagraph instrument (CGI) to image and spectrally characterize extrasolar planets. In this paper, we discuss the work that has been carried out at JPL in advancing Electron Multiplying CCD (EMCCD) technology to higher flight maturity, with the goal of reaching a NASA technology readiness level of 6 (TRL-6) by early-to-mid 2016. The EMCCD has been baselined for both the coronagraph's imager and integral field spectrograph (IFS) based on its sub-electron noise performance at extremely low flux levels - the regime where the AFTA CGI will operate. We present results from a study that fully characterizes the beginning of life performance of the EMCCD. We also discuss, and present initial results from, a recent radiation test campaign that was designed and carried out to mimic the conditions of the WFIRST-AFTA space environment in an L2 orbit, where we sought to assess the sensor's end of life performance, particularly degradation of its charge transfer efficiency, in addition to other parameters such as dark current, electron multiplication gain, clock induced charge and read noise.

  1. Preparation of a one-curie 171Tm target for the Detector for Advanced Neutron Capture Experiments (DANCE)

    SciTech Connect

    Schwantes, Jon M.; Taylor, Wayne A.; Rundberg, Robert S.; Vieira, David J.

    2008-05-15

    Roughly one curie of 171Tm (t1/2=1.92a) has been produced and purified for the purpose of making a nuclear target for the first measurements of its neutron capture cross section. Target preparation consisted of three key steps: (1) material production; (2) separation and purification; and (3) electrodeposition onto a suitable backing material. Approximately 1.5 mg of the target material (at the time of separation) was produced by irradiating roughly 250 mg of its stable enriched 170Er lanthanide neighbor with neutrons at the ILL reactor in France. This production method resulted in a “difficult-to-separate” 1:167 mixture of near-neighboring lanthanides, Tm and Er. Separation and purification was accomplished using high-performance liquid chromatorgraphy (HPLC), with a proprietary cation exchange column (Dionex, CS-3) and alpha-hydroxyisobutyric acid (a-HIB) eluent. This technique yielded a final product of ~95% purity with respect to Tm. A portion (20 ug) of the Tm was electrodeposited on thin Be foil and delivered to the Los Alamos Neutron Science CEnter (LANSCE) for preliminary analysis of its neutron capture cross section using the Detector for Advanced Neutron Capture Experiments (DANCE). This paper discusses the major hurdles associated with the separation and purification step including, scale-up issues related to the use of HPLC for material separation and purification of the target material from a-HIB and 4-(2-pyridylazo)resorcinol (PAR) colorant.

  2. Gamma-ray observations of supernova SN1987A by the balloonborne gamma-ray advanced detector

    SciTech Connect

    Coldwell, R.L.; Rester, A.C. ); Eichhorn, G. ); Starr, R.; Trombka, J.I. ); Lasche, G.P. )

    1988-01-01

    On 8 January 1988, gamma-ray advanced detector (GRAD) supernova observer was launched on a 3.3 x 10{sup 5} cubic meter helium balloon from Williams Field. The instrument maintained a float altitude of 36 kilometers as it drifted eastward along the 78{degrees}S parallel until it was brought down 320 kilometers east of Vostak Station on 10 January and recovered on 13 January. High-energy resolution gamma-ray spectra of the supernova SN1987A were taken; it is hoped that these spectra will provide evidence of explosive nucleosynthesis of the heavy elements in the supernova. Results. The earliest results of the analysis, showed evidence of gamma rays from the radioactive decay of the isotope cobalt-56, the longer-lived daughter of short-lived nickel-56, which was expected to be produced in great abundance in the supernova explosion, but the cobalt-56 line appearing most clearly in the supernova spectrum-the 1,238-kiloelectronvolt gamma-ray--was apparently split into two doppler-shifted and broadened components. This astonishing result appeared to suggest that the mantle of the supernova had expanded asymmetrically with a velocity in excess of 3,000 kilometers per second.

  3. Teaching Groups as Foci for Evaluating Performance in Cost-Effectiveness of GCE Advanced Level Provision: Some Practical Methodological Innovations.

    ERIC Educational Resources Information Center

    Fielding, Antony

    2002-01-01

    Analyzes subject teaching-group effectiveness in English and Welsh General Certification of Education (GCE) Advanced Level prior to a linking to resources; suggests cross-classified multilevel models with weighted random effects for disentangling student, group, and teacher effects; finds that teacher effects are considerable, but cannot find…

  4. Target selection and comparison of mission design for space debris removal by DLR's advanced study group

    NASA Astrophysics Data System (ADS)

    van der Pas, Niels; Lousada, Joao; Terhes, Claudia; Bernabeu, Marc; Bauer, Waldemar

    2014-09-01

    Space debris is a growing problem. Models show that the Kessler syndrome, the exponential growth of debris due to collisions, has become unavoidable unless an active debris removal program is initiated. The debris population in LEO with inclination between 60° and 95° is considered as the most critical zone. In order to stabilize the debris population in orbit, especially in LEO, 5 to 10 objects will need to be removed every year. The unique circumstances of such a mission could require that several objects are removed with a single launch. This will require a mission to rendezvous with a multitude of objects orbiting on different altitudes, inclinations and planes. Removal models have assumed that the top priority targets will be removed first. However this will lead to a suboptimal mission design and increase the ΔV-budget. Since there is a multitude of targets to choose from, the targets can be selected for an optimal mission design. In order to select a group of targets for a removal mission the orbital parameters and political constraints should also be taken into account. Within this paper a number of the target selection criteria are presented. The possible mission targets and their order of retrieval is dependent on the mission architecture. A comparison between several global mission architectures is given. Under consideration are 3 global missions of which a number of parameters are varied. The first mission launches multiple separate deorbit kits. The second launches a mother craft with deorbit kits. The third launches an orbital tug which pulls the debris in a lower orbit, after which a deorbit kit performs the final deorbit burn. A RoM mass and cost comparison is presented. The research described in this paper has been conducted as part of an active debris removal study by the Advanced Study Group (ASG). The ASG is an interdisciplinary student group working at the DLR, analyzing existing technologies and developing new ideas into preliminary

  5. Advanced analytical facilities report of the planetary materials and geochemistry working group

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The role of advanced analytical facilities; upgrading/replacement of the existing facilities; the relationship of advanced facilities to the present program; and possible facilities are examined. Major conclusions and recommendations are presented.

  6. Operation of the power information center: Performance of secretariat functions and information exchange activities in the advanced power field of the interagency advanced power group

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Highlights of activities conducted during the reporting period to facilitate the exchange of technical information among scientists and engineers both within the federal government and within industry are cited. Interagency Advanced Power Group meetings and special efforts, project briefs, and organization development are considered.

  7. Advanced Ionospheric Sensing using GROUP-C and LITES aboard the ISS

    NASA Astrophysics Data System (ADS)

    Budzien, S. A.; Stephan, A. W.; Chakrabarti, S.; Finn, S. C.; Cook, T.; Powell, S. P.; O'Hanlon, B.; Bishop, R. L.

    2015-12-01

    The GPS Radio Occultation and Ultraviolet Photometer Co-located (GROUP-C) and Limb-imaging Ionospheric and Thermospheric Extreme-ultraviolet Spectrograph (LITES) experiments are manifested for flight aboard the International Space Station (ISS) in 2016 as part of the Space Test Program Houston #5 payload. The two experiments provide technical development and risk-reduction for future DoD space weather sensors suitable for ionospheric specification, space situational awareness, and data products for global ionosphere assimilative models. In addition, the combined instrument complement of these two experiments offers a unique opportunity to study structures of the nighttime ionosphere. GROUP-C includes an advanced GPS receiver providing ionospheric electron density profiles and scintillation measurements and a high-sensitivity far-ultraviolet photometer measuring horizontal ionospheric gradients. LITES is an imaging spectrograph that spans 60-140 nm and will obtain high-cadence limb profiles of the ionosphere and thermosphere from 150-350 km altitude. In the nighttime ionosphere, recombination of O+ and electrons produces optically thin emissions at 91.1 and 135.6 nm that can be used to tomographically reconstruct the two-dimensional plasma distribution in the orbital plane below ISS altitudes. Ionospheric irregularities, such as plasma bubbles and blobs, are transient features of the low and middle latitude ionosphere with important implications for operational systems. Irregularity structures have been studied primarily using ground-based systems, though some spaced-based remote and in-situ sensing has been performed. An ionospheric observatory aboard the ISS would provide new capability to study low- and mid-latitude ionospheric structures on a global scale. By combining for the first time high-sensitivity in-track photometry, vertical ionospheric airglow spectrographic imagery, and recent advancements in UV tomography, high-fidelity tomographic reconstruction of

  8. Gaseous Detectors

    NASA Astrophysics Data System (ADS)

    Titov, Maxim

    Since long time, the compelling scientific goals of future high-energy physics experiments were a driving factor in the development of advanced detector technologies. A true innovation in detector instrumentation concepts came in 1968, with the development of a fully parallel readout for a large array of sensing elements - the Multi-Wire Proportional Chamber (MWPC), which earned Georges Charpak a Nobel prize in physics in 1992. Since that time radiation detection and imaging with fast gaseous detectors, capable of economically covering large detection volumes with low mass budget, have been playing an important role in many fields of physics. Advances in photolithography and microprocessing techniques in the chip industry during the past decade triggered a major transition in the field of gas detectors from wire structures to Micro-Pattern Gas Detector (MPGD) concepts, revolutionizing cell-size limitations for many gas detector applications. The high radiation resistance and excellent spatial and time resolution make them an invaluable tool to confront future detector challenges at the next generation of colliders. The design of the new micro-pattern devices appears suitable for industrial production. Novel structures where MPGDs are directly coupled to the CMOS pixel readout represent an exciting field allowing timing and charge measurements as well as precise spatial information in 3D. Originally developed for the high-energy physics, MPGD applications have expanded to nuclear physics, photon detection, astroparticle and neutrino physics, neutron detection, and medical imaging.

  9. The PixFEL project: development of advanced X-ray pixel detectors for application at future FEL facilities

    NASA Astrophysics Data System (ADS)

    Rizzo, G.; Comotti, D.; Fabris, L.; Grassi, M.; Lodola, L.; Malcovati, P.; Manghisoni, M.; Ratti, L.; Re, V.; Traversi, G.; Vacchi, C.; Batignani, G.; Bettarini, S.; Casarosa, G.; Forti, F.; Morsani, F.; Paladino, A.; Paoloni, E.; Dalla Betta, G.-F.; Pancheri, L.; Verzellesi, G.; Xu, H.; Mendicino, R.; Benkechkache, M. A.

    2015-02-01

    The PixFEL project aims to develop an advanced X-ray camera for imaging suited for the demanding requirements of next generation free electron laser (FEL) facilities. New technologies can be deployed to boost the performance of imaging detectors as well as future pixel devices for tracking. In the first phase of the PixFEL project, approved by the INFN, the focus will be on the development of the microelectronic building blocks, carried out with a 65 nm CMOS technology, implementing a low noise analog front-end channel with high dynamic range and compression features, a low power ADC and high density memory. At the same time PixFEL will investigate and implement some of the enabling technologies to assembly a seamless large area X-ray camera composed by a matrix of multilayer four-side buttable tiles. A pixel matrix with active edge will be developed to minimize the dead area of the sensor layer. Vertical interconnection of two CMOS tiers will be explored to build a four-side buttable readout chip with small pixel pitch and all the on-board required functionalities. The ambitious target requirements of the new pixel device are: single photon resolution, 1 to 104 photons @ 1 keV to 10 keV input dynamic range, 10-bit analog to digital conversion up to 5 MHz, 1 kevent in-pixel memory and 100 μm pixel pitch. The long term goal of PixFEL will be the development of a versatile X-ray camera to be operated either in burst mode (European XFEL), or in continuous mode to cope with the high frame rates foreseen for the upgrade phase of the LCLS-II at SLAC.

  10. Frequency-domain gravitational waves from nonprecessing black-hole binaries. II. A phenomenological model for the advanced detector era

    NASA Astrophysics Data System (ADS)

    Khan, Sebastian; Husa, Sascha; Hannam, Mark; Ohme, Frank; Pürrer, Michael; Forteza, Xisco Jiménez; Bohé, Alejandro

    2016-02-01

    We present a new frequency-domain phenomenological model of the gravitational-wave signal from the inspiral, merger and ringdown of nonprecessing (aligned-spin) black-hole binaries. The model is calibrated to 19 hybrid effective-one-body-numerical-relativity waveforms up to mass ratios of 1 ∶18 and black-hole spins of |a /m |˜0.85 (0.98 for equal-mass systems). The inspiral part of the model consists of an extension of frequency-domain post-Newtonian expressions, using higher-order terms fit to the hybrids. The merger ringdown is based on a phenomenological ansatz that has been significantly improved over previous models. The model exhibits mismatches of typically less than 1% against all 19 calibration hybrids and an additional 29 verification hybrids, which provide strong evidence that, over the calibration region, the model is sufficiently accurate for all relevant gravitational-wave astronomy applications with the Advanced LIGO and Virgo detectors. Beyond the calibration region the model produces physically reasonable results, although we recommend caution in assuming that any merger-ringdown waveform model is accurate outside its calibration region. As an example, we note that an alternative nonprecessing model, SEOBNRv2 (calibrated up to spins of only 0.5 for unequal-mass systems), exhibits mismatch errors of up to 10% for high spins outside its calibration region. We conclude that waveform models would benefit most from a larger number of numerical-relativity simulations of high-aligned-spin unequal-mass binaries.

  11. Advanced microbolometer detectors for a next-generation uncooled FPA for space-based thermal remote sensing

    NASA Astrophysics Data System (ADS)

    Williamson, Fraser; Marchese, Linda; Baldenberger, Georges; Châteauneuf, François; Provencal, Francis; Caron, Jean-Sol; Dupont, Fabien; Osouf, Jocelyne; Couture, Patrick; Ngo Phong, Linh; Pope, Tim

    2009-02-01

    INO has established a VOx-based uncooled microbolometer detector technology and an expertise in the development of custom detectors and focal plane arrays. Thanks to their low power consumption and broadband sensitivity, uncooled microbolometer detectors are finding an increased number of applications in the field of space-based thermal remote sensing. A mission requirement study has identified at least seven applications with a need for data in the MWIR (3-8 μm), LWIR (8-15 μm) and or FIR (15-100 μm) wavelength bands. The requirement study points to the need for two main classes of uncooled thermal detectors, the first requiring small and fast detectors for MWIR and LWIR imaging with small ground sampling distance, and the second requiring larger detectors with sensitivity out to the FIR. In this paper, the simulation, design, microfabrication and radiometric testing of detectors for these two classes of requirements will be presented. The performance of the experimental detectors closely approach the mission requirements and show the potential of microbolometer technology to fulfill the requirements of future space based thermal imaging missions.

  12. Recent Research with the Detector for Advanced Neutron Capture Experiments (dance) at the LOS Alamos Neutron Science Center

    NASA Astrophysics Data System (ADS)

    Ullmann, J. L.

    2014-09-01

    The DANCE detector at Los Alamos is a 160 element, nearly 4π BaF2 detector array designed to make measurements of neutron capture on rare or radioactive nuclides. It has also been used to make measurements of gamma-ray multiplicity following capture and gamma-ray output from fission. Several examples of measurements are briefly discussed.

  13. Hybrid deterministic and stochastic x-ray transport simulation for transmission computed tomography with advanced detector noise model

    NASA Astrophysics Data System (ADS)

    Popescu, Lucretiu M.

    2016-03-01

    We present a model for simulation of noisy X-ray computed tomography data sets. The model is made of two main components, a photon transport simulation component that generates the noiseless photon field incident on the detector, and a detector response model that takes as input the incident photon field parameters and given the X-ray source intensity and exposure time can generate noisy data sets, accordingly. The photon transport simulation component combines direct ray-tracing of polychromatic X-rays for calculation of transmitted data, with Monte Carlo simulation for calculation of the scattered-photon data. The Monte Carlo scatter simulation is accelerated by implementing particle splitting and importance sampling variance reduction techniques. The detector-incident photon field data are stored as energy expansion coefficients on a refined grid that covers the detector area. From these data the detector response model is able to generate noisy detector data realizations, by reconstituting the main parameters that describe each detector element response in statistical terms, including spatial correlations. The model is able to generate very fast, on the fly, CT data sets corresponding to different radiation doses, as well as detector response characteristics, facilitating data management in extensive optimization studies by reducing the computation time and storage space demands.

  14. {A Review of Working Group 2 (Advanced Terrestrial Systems) of the COST 296 Action}

    NASA Astrophysics Data System (ADS)

    Warrington, E. M.; Tulunay, E.

    2009-04-01

    E.M. Warrington, E. Tulunay, N.M. Abbasi, J. Azevedo, L. Bertel, A. Bourdillon, E. Benito, C. Bianchi, A. Casimiro, L. Economou, Y. Erhel, S.M. Feeney, S.D. Gunashekar, H. Haralambous, D. Lemur, F. Marie, J.P. Monilie, M. Muriuki, M. Oger M. Pietrella, V. Rannou, H. Rothkaehl, S. Saillant, S. Salous, O. Sari, A.J. Stocker, H.J. Strangeways, Y. Tulunay and N.Y. Zaalov This paper deals with the research undertaken during the COST 296 Action in Working Group 2 on Advanced Terrestrial Systems. The Working Group comprised three work packages covering various topics: Radar and Radiolocation, HF/MF Communications, and Spectrum Management. Results from this Working Group are presented in this paper, and may be summarised as follows. Aspects of HF propagation The propagation characteristics of radio signals are important parameters to consider when designing and operating radio systems. From the point of view Working Group 2 of the COST-296 Action, interest lies with effects associated with propagation via the ionosphere of signals within the HF band. Several aspects were covered: The directions of arrival and times of flight of signals received over a path oriented along the trough have been examined and several types of propagation effects identified. Of particular note, combining the HF observations with satellite measurements has identified the presence of irregularities within the floor of the trough that result in propagation displaced from the great circle direction. An understanding of the propagation effects that result in deviations of the signal path from the great circle direction are of particular relevance to the operation of HF radiolocation systems. Inclusion of the results from the above mentioned measurements into a propagation model of the northerly ionosphere (i.e. those regions of the ionosphere located poleward of, and including, the mid-latitude trough) and the use of this model to predict the coverage expected from transmitters where the signals

  15. Interagency Advanced Power Group, Joint Electrical and Nuclear Working Group, meeting minutes, November 16--17, 1993

    SciTech Connect

    Not Available

    1993-12-31

    Reports on soldier power R&D review, N-MCT power electronic building blocks, silicon carbide power semiconductor work, and ground based radar were made to the Power Conditioning Panel. An introduction to high temperature electronics needs, research and development was made to the High Temperature Electronics Subcommittee. The Pulse Power Panel received reports on the navy ETC gun, and army pulse power. The Superconductivity Panel received reports on high-tc superconducting wires, superconducting magnetic energy storage, and superconducting applications. The Nuclear Working Group received presentations on the Topaz nuclear power program, and space nuclear work in the Department of Energy.

  16. SNM Movement Detection/Radiation Sensors and Advanced Materials Portfolio Review, CdMnTe (CMT) Gamma Ray Detectors

    SciTech Connect

    Bolotnikov,A.

    2009-06-02

    The project goals are: (1) Develop CMT radiation detectors - Demonstrate feasibility (Phase 1 is complete) and Improve material properties and device performance; (2) This project will lead to novel radiation detectors - high detection efficiency, high energy-resolution, ambient-temperature operation, and low production cost; and (3) Such detectors are needed in areas of nonproliferation and national security for detection of SNM. Research highlights are: (1) We achieved our Phase-I goal - Demonstration of CMT detector performance approaching that of CZT detectors; (2) Demonstrated that In-doped CMT is much closer to its anticipated performance as radiation detectors than other alternative materials, TlBr and HgI{sub 2} - Large crystal volumes, 10{sup 10}{Omega}{center_dot}cm, 3 x 10{sup -3}cm{sup 2}/V, and stable response; and (3) Conducted material and device characterization experiments - Detectors: I-V, {mu}{sub e}, ({mu}{tau}){sub e}, internal E fields, energy spectra, and high-resolution x-ray response mapping data and Materials - DLTS, TCT, PL, EPDs, XRD, PCD and IR transmission.

  17. Advances in Telescope and Detector Technologies - Impacts on the Study and Understanding of Binary Star and Exoplanet Systems

    NASA Astrophysics Data System (ADS)

    Guinan, Edward F.; Engle, Scott; Devinney, Edward J.

    2012-04-01

    Current and planned telescope systems (both on the ground and in space) as well as new technologies will be discussed with emphasis on their impact on the studies of binary star and exoplanet systems. Although no telescopes or space missions are primarily designed to study binary stars (what a pity!), several are available (or will be shortly) to study exoplanet systems. Nonetheless those telescopes and instruments can also be powerful tools for studying binary and variable stars. For example, early microlensing missions (mid-1990s) such as EROS, MACHO and OGLE were initially designed for probing dark matter in the halos of galaxies but, serendipitously, these programs turned out to be a bonanza for the studies of eclipsing binaries and variable stars in the Magellanic Clouds and in the Galactic Bulge. A more recent example of this kind of serendipity is the Kepler Mission. Although Kepler was designed to discover exoplanet transits (and so far has been very successful, returning many planetary candidates), Kepler is turning out to be a ``stealth'' stellar astrophysics mission returning fundamentally important and new information on eclipsing binaries, variable stars and, in particular, providing a treasure trove of data of all types of pulsating stars suitable for detailed Asteroseismology studies. With this in mind, current and planned telescopes and networks, new instruments and techniques (including interferometers) are discussed that can play important roles in our understanding of both binary star and exoplanet systems. Recent advances in detectors (e.g. laser frequency comb spectrographs), telescope networks (both small and large - e.g. Super-WASP, HAT-net, RoboNet, Las Combres Observatory Global Telescope (LCOGT) Network), wide field (panoramic) telescope systems (e.g. Large Synoptic Survey Telescope (LSST) and Pan-Starrs), huge telescopes (e.g. the Thirty Meter Telescope (TMT), the Overwhelming Large Telescope (OWL) and the Extremely Large Telescope (ELT

  18. 40 CFR 35.4095 - What can my group pay for with an advance payment?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... used only for the purchase of supplies, postage, the payment of the first deposit to open a bank... for contracts for technical advisors or other contractors. (c) Advance payments are not available...

  19. {A Review of Working Group 2 (Advanced Terrestrial Systems) of the COST 296 Action}

    NASA Astrophysics Data System (ADS)

    Warrington, E. M.; Tulunay, E.

    2009-04-01

    E.M. Warrington, E. Tulunay, N.M. Abbasi, J. Azevedo, L. Bertel, A. Bourdillon, E. Benito, C. Bianchi, A. Casimiro, L. Economou, Y. Erhel, S.M. Feeney, S.D. Gunashekar, H. Haralambous, D. Lemur, F. Marie, J.P. Monilie, M. Muriuki, M. Oger M. Pietrella, V. Rannou, H. Rothkaehl, S. Saillant, S. Salous, O. Sari, A.J. Stocker, H.J. Strangeways, Y. Tulunay and N.Y. Zaalov This paper deals with the research undertaken during the COST 296 Action in Working Group 2 on Advanced Terrestrial Systems. The Working Group comprised three work packages covering various topics: Radar and Radiolocation, HF/MF Communications, and Spectrum Management. Results from this Working Group are presented in this paper, and may be summarised as follows. Aspects of HF propagation The propagation characteristics of radio signals are important parameters to consider when designing and operating radio systems. From the point of view Working Group 2 of the COST-296 Action, interest lies with effects associated with propagation via the ionosphere of signals within the HF band. Several aspects were covered: The directions of arrival and times of flight of signals received over a path oriented along the trough have been examined and several types of propagation effects identified. Of particular note, combining the HF observations with satellite measurements has identified the presence of irregularities within the floor of the trough that result in propagation displaced from the great circle direction. An understanding of the propagation effects that result in deviations of the signal path from the great circle direction are of particular relevance to the operation of HF radiolocation systems. Inclusion of the results from the above mentioned measurements into a propagation model of the northerly ionosphere (i.e. those regions of the ionosphere located poleward of, and including, the mid-latitude trough) and the use of this model to predict the coverage expected from transmitters where the signals

  20. Neutron radiography as a non-destructive method for diagnosing neutron converters for advanced thermal neutron detectors

    NASA Astrophysics Data System (ADS)

    Muraro, A.; Albani, G.; Perelli Cippo, E.; Croci, G.; Angella, G.; Birch, J.; Cazzaniga, C.; Caniello, R.; Dell'Era, F.; Ghezzi, F.; Grosso, G.; Hall-Wilton, R.; Höglund, C.; Hultman, L.; Schimdt, S.; Robinson, L.; Rebai, M.; Salvato, G.; Tresoldi, D.; Vasi, C.; Tardocchi, M.

    2016-03-01

    Due to the well-known problem of 3He shortage, a series of different thermal neutron detectors alternative to helium tubes are being developed, with the goal to find valid candidates for detection systems for the future spallation neutron sources such as the European Spallation Source (ESS). A possible 3He-free detector candidate is a charged particle detector equipped with a three dimensional neutron converter cathode (3D-C). The 3D-C currently under development is composed by a series of alumina (Al2O3) lamellas coated by 1 μ m of 10B enriched boron carbide (B4C). In order to obtain a good characterization in terms of detector efficiency and uniformity it is crucial to know the thickness, the uniformity and the atomic composition of the B4C neutron converter coating. In this work a non-destructive technique for the characterization of the lamellas that will compose the 3D-C was performed using neutron radiography. The results of these measurements show that the lamellas that will be used have coating uniformity suitable for detector applications. This technique (compared with SEM, EDX, ERDA, XPS) has the advantage of being global (i.e. non point-like) and non-destructive, thus it is suitable as a check method for mass production of the 3D-C elements.

  1. Meaning-Centered Group Psychotherapy: An Effective Intervention for Improving Psychological Well-Being in Patients With Advanced Cancer

    PubMed Central

    Breitbart, William; Rosenfeld, Barry; Pessin, Hayley; Applebaum, Allison; Kulikowski, Julia; Lichtenthal, Wendy G.

    2015-01-01

    Purpose To test the efficacy of meaning-centered group psychotherapy (MCGP) to reduce psychological distress and improve spiritual well-being in patients with advanced or terminal cancer. Patients and Methods Patients with advanced cancer (N = 253) were randomly assigned to manualized eight-session interventions of either MCGP or supportive group psychotherapy (SGP). Patients were assessed before and after completing the treatment and 2 months after treatment. The primary outcome measures were spiritual well-being and overall quality of life, with secondary outcome measures assessing depression, hopelessness, desire for hastened death, anxiety, and physical symptom distress. Results Hierarchical linear models that included a priori covariates and only participants who attended ≥ three sessions indicated a significant group × time interaction for most outcome variables. Specifically, patients receiving MCGP showed significantly greater improvement in spiritual well-being and quality of life and significantly greater reductions in depression, hopelessness, desire for hastened death, and physical symptom distress compared with those receiving SGP. No group differences were observed for changes in anxiety. Analyses that included all patients, regardless of whether they attended any treatment sessions (ie, intent-to-treat analyses), and no covariates still showed significant treatment effects (ie, greater benefit for patients receiving MCGP v SGP) for quality of life, depression, and hopelessness but not for other outcome variables. Conclusion This large randomized controlled study provides strong support for the efficacy of MCGP as a treatment for psychological and existential or spiritual distress in patients with advanced cancer. PMID:25646186

  2. Facebook and Classroom Group Work: A Trial Study Involving University of Botswana Advanced Oral Presentation Students

    ERIC Educational Resources Information Center

    Magogwe, Joel M.; Ntereke, Beauty; Phetlhe, Keith R.

    2015-01-01

    In the 21st century, the use of information technology in the classroom is advancing rapidly, especially in higher education. The Internet, through social networking, has made it possible for students to learn and teachers to teach outside the classroom walls. Facebook in particular has made it possible for students to interact and communicate…

  3. 40 CFR 35.4090 - If my group is eligible for an advance payment, how do we get our funds?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false If my group is eligible for an advance payment, how do we get our funds? 35.4090 Section 35.4090 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance How You Get the Money § 35.4090 If...

  4. 40 CFR 35.4090 - If my group is eligible for an advance payment, how do we get our funds?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false If my group is eligible for an advance payment, how do we get our funds? 35.4090 Section 35.4090 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance How You Get the Money § 35.4090 If...

  5. 40 CFR 35.4090 - If my group is eligible for an advance payment, how do we get our funds?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false If my group is eligible for an advance payment, how do we get our funds? 35.4090 Section 35.4090 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance How You Get the Money § 35.4090 If...

  6. Advancing Entrepreneurship Education. A Report of the Youth Entrepreneurship Strategy Group

    ERIC Educational Resources Information Center

    Aspen Institute, 2008

    2008-01-01

    The Youth Entrepreneurship Strategy Group convened its inaugural meeting from September 26-28, 2007 at the Aspen Institute in Aspen, Colorado. A group of dynamic national leaders from the fields of education, entrepreneurship and business, public policy, media, and philanthropy met over three days to explore the promise of, and obstacles to,…

  7. Design of an advanced positron emission tomography detector system and algorithms for imaging small animal models of human disease

    NASA Astrophysics Data System (ADS)

    Foudray, Angela Marie Klohs

    Detecting, quantifying and visualizing biochemical mechanism in a living system without perturbing function is the goal of the instrument and algorithms designed in this thesis. Biochemical mechanisms of cells have long been known to be dependent on the signals they receive from their environment. Studying biological processes of cells in-vitro can vastly distort their function, since you are removing them from their natural chemical signaling environment. Mice have become the biological system of choice for various areas of biomedical research due to their genetic and physiological similarities with humans, the relatively low cost of their care, and their quick breeding cycle. Drug development and efficacy assessment along with disease detection, management, and mechanism research all have benefited from the use of small animal models of human disease. A high resolution, high sensitivity, three-dimensional (3D) positioning positron emission tomography (PET) detector system was designed through device characterization and Monte Carlo simulation. Position-sensitive avalanche photodiodes (PSAPDs) were characterized in various packaging configurations; coupled to various configurations of lutetium oxyorthosilicate (LSO) scintillation crystals. Forty novelly packaged final design devices were constructed and characterized, each providing characteristics superior to commercially available scintillation detectors used in small animal imaging systems: ˜1mm crystal identification, 14-15% of 511 keV energy resolution, and averaging 1.9 to 5.6 ns coincidence time resolution. A closed-cornered box-shaped detector configuration was found to provide optimal photon sensitivity (˜10.5% in the central plane) using dual LSO-PSAPD scintillation detector modules and Monte Carlo simulation. Standard figures of merit were used to determine optimal system acquisition parameters. A realistic model for constituent devices was developed for understanding the signals reported by the

  8. Advanced X-ray Astrophysics Facility (AXAF): Science working group report. [space shuttle payload

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The Advanced X-Ray Astrophysics Facility (AXAF) mission concept is examined from a scientific viewpoint. A brief description of the development of X-ray astronomy and a summary description of AXAF, the scientific objectives of the facility, a description of representative scientific instruments, requirements for X-ray ground testing, and a summary of studies related to spacecraft and support subsystems, are included.

  9. Development of Collaborative Research Initiatives to Advance the Aerospace Sciences-via the Communications, Electronics, Information Systems Focus Group

    NASA Technical Reports Server (NTRS)

    Knasel, T. Michael

    1996-01-01

    The primary goal of the Adaptive Vision Laboratory Research project was to develop advanced computer vision systems for automatic target recognition. The approach used in this effort combined several machine learning paradigms including evolutionary learning algorithms, neural networks, and adaptive clustering techniques to develop the E-MOR.PH system. This system is capable of generating pattern recognition systems to solve a wide variety of complex recognition tasks. A series of simulation experiments were conducted using E-MORPH to solve problems in OCR, military target recognition, industrial inspection, and medical image analysis. The bulk of the funds provided through this grant were used to purchase computer hardware and software to support these computationally intensive simulations. The payoff from this effort is the reduced need for human involvement in the design and implementation of recognition systems. We have shown that the techniques used in E-MORPH are generic and readily transition to other problem domains. Specifically, E-MORPH is multi-phase evolutionary leaming system that evolves cooperative sets of features detectors and combines their response using an adaptive classifier to form a complete pattern recognition system. The system can operate on binary or grayscale images. In our most recent experiments, we used multi-resolution images that are formed by applying a Gabor wavelet transform to a set of grayscale input images. To begin the leaming process, candidate chips are extracted from the multi-resolution images to form a training set and a test set. A population of detector sets is randomly initialized to start the evolutionary process. Using a combination of evolutionary programming and genetic algorithms, the feature detectors are enhanced to solve a recognition problem. The design of E-MORPH and recognition results for a complex problem in medical image analysis are described at the end of this report. The specific task involves the

  10. Pyroelectric detectors

    NASA Technical Reports Server (NTRS)

    Haller, Eugene E.; Beeman, Jeffrey; Hansen, William L.; Hubbard, G. Scott; Mcmurray, Robert E., Jr.

    1990-01-01

    The multi-agency, long-term Global Change programs, and specifically NASA's Earth Observing system, will require some new and advanced photon detector technology which must be specifically tailored for long-term stability, broad spectral range, cooling constraints, and other parameters. Whereas MCT and GaAs alloy based photovoltaic detectors and detector arrays reach most impressive results to wavelengths as long as 12 microns when cooled to below 70 K, other materials, such as ferroelectrics and pyroelectrics, appear to offer special opportunities beyond 12 microns and above 70 K. These materials have found very broad use in a wide variety of room temperature applications. Little is known about these classes of materials at sub-room temperatures and no photon detector results have been reported. From the limited information available, researchers conclude that the room temperature values of D asterisk greater than or equal to 10(exp 9) cm Hz(exp 1/2)/W may be improved by one to two orders of magnitude upon cooling to temperatures around 70 K. Improvements of up to one order of magnitude appear feasible for temperatures achievable by passive cooling. The flat detector response over a wavelength range reaching from the visible to beyond 50 microns, which is an intrinsic advantage of bolometric devices, makes for easy calibration. The fact that these materials have been developed for reduced temperature applications makes ferro- and pyroelectric materials most attractive candidates for serious exploration.

  11. Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer

    PubMed Central

    Applebaum, Allison J.; Lichtenthal, Wendy G.; Pessin, Hayley A.; Radomski, Julia N.; Gökbayrak, N. Simay; Katz, Aviva M.; Rosenfeld, Barry; Breitbart, William

    2013-01-01

    Objective The generalizability of palliative care intervention research is often limited by high rates of study attrition. This study examined factors associated with attrition from a randomized controlled trial comparing meaning-centered group psychotherapy (MCGP), an intervention designed to help advanced cancer patients sustain or enhance their sense of meaning to the supportive group psychotherapy (SGP), a standardized support group. Methods Patients with advanced solid tumor cancers (n = 153) were randomized to eight sessions of either the MCGP or SGP. They completed assessments of psychosocial, spiritual, and physical well-being pretreatment, midtreatment, and 2 months post-treatment. Attrition was assessed in terms of the percent of participants who failed to complete these assessments, and demographic, psychiatric, medical, and study-related correlates of attrition were examined for the participants in each of these categories. Results The rates of attrition at these time points were 28.1%, 17.7%, and 11.1%, respectively; 43.1% of the participants (66 of 153) completed the entire study. The most common reason for dropout was patients feeling too ill. Attrition rates did not vary significantly between study arms. The participants who dropped out pretreatment reported less financial concerns than post-treatment dropouts, and the participants who dropped out of the study midtreatment had poorer physical health than treatment completers. There were no other significant associations between attrition and any demographic, medical, psychiatric, or study-related variables. Conclusions These findings highlight the challenge of maintaining advanced cancer patients in longitudinal research and suggest the need to consider alternative approaches (e.g., telemedicine) for patients who might benefit from group interventions but are too ill to travel. PMID:21751295

  12. Adaptive Radiation in Socially Advanced Stem-Group Ants from the Cretaceous.

    PubMed

    Barden, Phillip; Grimaldi, David A

    2016-02-22

    Across terrestrial ecosystems, modern ants are ubiquitous. As many as 94 out of every 100 individual arthropods in rainforests are ants, and they constitute up to 15% of animal biomass in the Amazon. Moreover, ants are pervasive agents of natural selection as over 10,000 arthropod species are specialized inquilines or myrmecomorphs living among ants or defending themselves through mimicry. Such impact is traditionally explained by sociality: ants are the first major group of ground-dwelling predatory insects to become eusocial, increasing efficiency of tasks and establishing competitive superiority over solitary species. A wealth of specimens from rich deposits of 99 million-year-old Burmese amber resolves ambiguity regarding sociality and diversity in the earliest ants. The stem-group genus Gerontoformica maintained distinct reproductive castes including morphotypes unknown in solitary aculeate (stinging) wasps, providing insight into early behavior. We present rare aggregations of workers, indicating group recruitment as well as an instance of interspecific combat; such aggression is a social feature of modern ants. Two species and an unusual new genus are described, further expanding the remarkable diversity of early ants. Stem-group ants are recovered as a paraphyletic assemblage at the base of modern lineages varying greatly in size, form, and mouthpart structure, interpreted here as an adaptive radiation. Though Cretaceous stem-group ants were eusocial and adaptively diverse, we hypothesize that their extinction resulted from the rise of competitively superior crown-group taxa that today form massive colonies, consistent with Wilson and Hölldobler's concept of "dynastic succession." PMID:26877084

  13. Caribbean Families: Diversity among Ethnic Groups. Advances in Applied Developmental Psychology, Volume 14.

    ERIC Educational Resources Information Center

    Roopnarine, Jaipaul L., Ed.; Brown, Janet, Ed.

    Little is known about the development and function of families in major Caribbean communities, an area composed of diverse ethnic and political groups, the majority of whom live on the edge of poverty. This edited book provides an interdisciplinary examination of Caribbean families, each chapter detailing studies dealing with family structures and…

  14. Group Work during International Disaster Outreach Projects: A Model to Advance Cultural Competence

    ERIC Educational Resources Information Center

    West-Olatunji, Cirecie; Henesy, Rachel; Varney, Melanie

    2015-01-01

    Given the rise in disasters worldwide, counselors will increasingly be called upon to respond. Current accreditation standards require that programs train students to become skillful in disaster/crisis interventions. Group processing to enhance self-awareness and improve conceptualization skills is an essential element of such training. This…

  15. Advances in the development of complexes that contain a group 13 element chalcogen multiple bond.

    PubMed

    Franz, Daniel; Inoue, Shigeyoshi

    2016-06-21

    Inorganic group 13 element (M) chalcogenides (E) based on the general formular M2E3 are ubiquitous in synthesis, catalysis and material science. The parent ME fragment which aggregates to form three dimensional networks in the condensed phase can be expected to exhibit multiple bond character between the elements. Low temperature matrix isolation techniques are required to investigate the nature of this elusive species. An alternate approach for respective studies is the synthesis of electron-precise molecular complexes that contain the ME entity and for which isolation at ambient temperature is possible. This is realized by kinetic stabilization with bulky ligands and thermodynamic stabilization using electron donor, as well as acceptor groups attached to the ME functionality (i.e. donor-acceptor stabilization). In this article we revise the literature on complex compounds that exhibit a bonding interaction between a group 13 element atom and a chalcogen atom that is reasonably to be interpreted in terms of a double- or triple bond. PMID:27216700

  16. The Origin and Advancement of Cardiovascular Physiology in Brazil: The Contribution of Eduardo Krieger to Research Groups

    PubMed Central

    Vasquez, Elisardo C.

    2016-01-01

    Since 1996, symposia devoted to the discussion of advances in cardiovascular physiology have been alternately organized by Brazilian research groups, most of which were created or joined by Ph.D. trainees of Eduardo M Krieger. Therefore, as Frontiers in Physiology is publishing a topic devoted to the celebration of the 20th edition of the Brazilian Symposium of Cardiovascular Physiology, it is a great opportunity to talk about the contributions of Eduardo Krieger to the development of cardiovascular physiology. In this historical mini-review, first, the influence of the Argentinian group of Bernardo Houssay and Braun Menéndez on cardiovascular physiology in Brazil is discussed. Second, the contribution of Eduardo Krieger to the creation of several of those groups and to the development of science and technology is reviewed. Finally, the origin and consolidation of the group of Vitoria is highlighted as an example of a research group that was influenced by the University of Sao Paulo-Faculty of Medicine of Ribeirao Preto and has trained hundreds of Master and Ph.D. students in the area of cardiovascular research. PMID:27148073

  17. Working Group summary reports from the Advanced Photon Source reliability workshop

    SciTech Connect

    Not Available

    1992-05-01

    A workshop was held at APS to address reliability goals for accelerator systems. Seventy-one individuals participated in the workshop, including 30 from other institutions. The goals of the workshop were to: (1) Give attendees an introduction to the basic concepts of reliability analysis. (2) Exchange information on operating experience at existing accelerator facilities and strategies for achieving reliability at facilities under design or in construction. (3) Discuss reliability goals for APS and the means of their achievement. This report contains the working group summary report an APS`s following systems: RF Systems; Power Supplies; Magnet Systems; Interlock and Diagnostics; and Vacuum Systems.

  18. Working Group summary reports from the Advanced Photon Source reliability workshop

    SciTech Connect

    Not Available

    1992-05-01

    A workshop was held at APS to address reliability goals for accelerator systems. Seventy-one individuals participated in the workshop, including 30 from other institutions. The goals of the workshop were to: (1) Give attendees an introduction to the basic concepts of reliability analysis. (2) Exchange information on operating experience at existing accelerator facilities and strategies for achieving reliability at facilities under design or in construction. (3) Discuss reliability goals for APS and the means of their achievement. This report contains the working group summary report an APS's following systems: RF Systems; Power Supplies; Magnet Systems; Interlock and Diagnostics; and Vacuum Systems.

  19. A Consideration of Future Flight Material Exposure Experiments in Japan: Advanced Material Exposure Test Working Group's Proposal

    NASA Astrophysics Data System (ADS)

    Tagawa, Masahito; Yokota, Kumiko; Cho, Mengu; Iwata, Minoru; Yokota, Rikio; Suzuki, Mineo; Matsumoto, Koji; Kimoto, Yugo; Miyazaki, Eiji; Shimamura, Hiroyuki

    In Japan, the largest material exposure program “SM/MPAC&SEED (Service Module/ Micro-Particles Capturer and Space Environment Exposure Device) Experiment” has been completed. This program is quite ambitious among the other Japanese materials exposure tests; 3 sets of samples have been exposed for 1, 2 and 3 years in orbit in order to discover the fluence dependence of the material responses. We have learned a lot of lessons from this program. Based on the lessons learned, the “Advanced Material Exposure Test Working Group” has been established by the Committee on Space Utilization in 2007. This working group discussed the current problems of the material exposure program (flight tests) and proposed the future direction of the experimental methodologies. In this presentation, problems and new challenges discussed in this working group will be discussed.

  20. Prognostic risk factors in advanced Hodgkin's lymphoma. Report of the German Hodgkin Study Group.

    PubMed

    Loeffler, M; Pfreundschuh, M; Hasenclever, D; Hiller, E; Gerhartz, H; Wilmanns, W; Rohloff, R; Rühl, U; Kühn, G; Fuchs, R

    1988-06-01

    In a national multicentre trial in the FRG patients with Hodgkin's lymphoma in stages CS/PS III B/IV were entered into the HD 3 protocol and received induction chemotherapy with 3 x (COPP + ABVD). Patients in complete remission (CR) received consolidation therapy by either radiotherapy (20 Gy IF) or chemotherapy (COPP + ABVD). Patients not in CR received salvage therapy (40 Gy in case of persisting nodal disease, else 4 x CEVD chemotherapy). Between July 1983 and May 1987 230 untreated patients aged 15 to 60 qualified for this HD 3 protocol. This analysis is based on the first 137 patients evaluable for response. Of these, 86 (63%) achieved CR after induction chemotherapy. Including salvage therapy a total of 104 patients (76%) achieved CR. Univariate and multivariate prognostic risk factor analyses were performed using freedom from treatment failure (FFTF) as endpoint. Sex, age, splenectomy, bone marrow, liver and bone involvement had no prognostic impact nor had stage according to the Ann Arbor classification. In contrast, a pretreatment erythrocyte sedimentation rate (ESR) above 80 mm/h and a serum alkaline phosphatase (AP) above 230 IU/ml appeared as significant risk factors (p less than 0.01, relative risk 2.3). The two parameters were not independent. Comparing a group A (ESR less than or equal to 80 and AP less than or equal to 230) versus a pooled group B (ESR greater than 80 and/or AP greater than 230) increased the difference (p less than 0.001, relative risk of 2.8) which was also significant for survival (p less than 0.04). PMID:2454691

  1. Recent Advances in Sarcopenia Research in Asia: 2016 Update From the Asian Working Group for Sarcopenia.

    PubMed

    Chen, Liang-Kung; Lee, Wei-Ju; Peng, Li-Ning; Liu, Li-Kuo; Arai, Hidenori; Akishita, Masahiro

    2016-08-01

    Sarcopenia was recently classified a geriatric syndrome and is a major challenge to healthy aging. Affected patients tend to have worse clinical outcomes and higher mortality than those without sarcopenia. Although there is general agreement on the principal diagnostic characteristics, initial thresholds for muscle mass, strength, and physical performance were based on data from populations of predominantly Europid ancestry and may not apply worldwide. The Asian Working Group for Sarcopenia (AWGS) issued regional consensus guidelines in 2014, and many more research studies from Asia have since been published; this review summarizes recent progress. The prevalence of sarcopenia estimated by the AWGS criteria ranges between 4.1% and 11.5% of the general older population; however, prevalence rates were higher in Asian studies that used European Working Group on Sarcopenia in Older People cut-offs. Risk factors include age, sex, heart disease, hyperlipidemia, daily alcohol consumption, and low protein or vitamin intake; physical activity is protective. Adjusting skeletal muscle mass by weight rather than height is better in showing the effect of older age in sarcopenia and identifying sarcopenic obesity; however, some Asian studies found no significant skeletal muscle loss, and muscle strength might be a better indicator. Although AWGS 2014 diagnostic cut-offs were generally well accepted, some may require further revision in light of conflicting evidence from some studies. The importance of sarcopenia in diverse therapeutic areas is increasingly evident, with strong research interest in sarcopenic obesity and the setting of malignancy. Pharmacologic interventions have been unsatisfactory, and the core management strategies remain physical exercise and nutritional supplementation; however, further research is required to determine the most beneficial approaches. PMID:27372539

  2. Pazopanib and depot octreotide in advanced, well-differentiated neuroendocrine tumours: a multicentre, single-group, phase 2 study

    PubMed Central

    Phan, Alexandria T; Halperin, Daniel M; Chan, Jennifer A; Fogelman, David R; Hess, Kenneth R; Malinowski, Paige; Regan, Eileen; Ng, Chaan S; Yao, James C; Kulke, Matthew H

    2015-01-01

    Summary Background Treatment options for advanced, well-differentiated neuroendocrine tumours (NETs) remain scarce. Pazopanib is an orally bioavailable, small molecule, multitargeted kinase inhibitor that inhibits VEGF receptors 1, 2, and 3. We did a study of the efficacy of pazopanib with depot octreotide in patients with advanced NETs. Methods We did a parallel cohort study of patients with metastatic or locally advanced grade 1–2 carcinoid tumours or pancreatic NETs, by use of a single-group, two-stage design. Patients received pazopanib 800 mg orally once per day and octreotide at their preprotocol dosage. The primary endpoint was the proportion of patients achieving an objective response, as assessed by investigators, by intention-to-treat analysis. This study is registered with ClinicalTrials.gov, identifier NCT00454363, and was completed in March, 2014. Findings Between April 12, 2007, and July 2, 2009, we enrolled 52 patients, including 32 individuals with pancreatic NETs and 20 individuals with carcinoid tumours. Seven (21.9%, 95% CI 11.0–38.8) of 32 patients with pancreatic NETs achieved an objective response. We detected no responses in the first stage of the cohort with carcinoid tumours, and we terminated accrual at 20 patients. Toxic effects included one patient with grade 4 hypertriglyceridaemia and one with grade 4 thrombosis, with the most common grade three events being aminotransferase increases and neutropenia, each of which happened in 3 patients. In all 52 patients, the most frequently observed toxic effects were fatigue (39 [75%]), nausea (33 [63%]), diarrhoea (33 [63%]), and hypertension (28 [54%]). Interpretation Treatment with pazopanib is associated with tumour response for patients with pancreatic NETs, but not for carcinoid tumours; a randomised controlled phase 3 study to assess pazopanib in advanced pancreatic NETs is warranted. Funding US National Cancer Institute of the National Institutes of Health. PMID:25956795

  3. The role of prophylactic cranial irradiation in regionally advanced non-small cell lung cancer. A Southwest Oncology Group Study

    SciTech Connect

    Rusch, V.W.; Griffin, B.R.; Livingston, R.B. )

    1989-10-01

    Lung cancer is the most common malignant disease in the United States. Only the few tumors detected very early are curable, but there has been some progress in the management of more advanced non-small cell lung cancer, particularly in regionally inoperable disease. Prevention of central nervous system relapse is an important issue in this group of patients because brain metastases ultimately develop in 20% to 25% of them. Seventy-three patients with regionally advanced non-small cell lung cancer were entered into a Phase II trial of neutron chest radiotherapy sandwiched between four cycles of chemotherapy including cisplatin, vinblastine, and mitomycin C. Prophylactic cranial irradiation was administered concurrently with chest radiotherapy (3000 cGy in 10 fractions in 15 patients; 3600 cGy in 18 fractions in the remaining 50 patients). Patients underwent computed tomographic scan of the brain before treatment and every 3 months after treatment. The initial overall response rate was 79%, but 65 of the 73 patients have subsequently died of recurrent disease. Median follow-up is 9 months for all 73 patients and 26 months for eight long-term survivors. No patient who completed the prophylactic cranial irradiation program had clinical or radiologic brain metastases. Toxic reactions to prophylactic cranial irradiation included reversible alopecia in all patients, progressive dementia in one patient, and possible optic neuritis in one patient. Both of these patients received 300 cGy per fraction of irradiation. The use of prophylactic cranial irradiation has been controversial, but its safety and efficacy in this trial supports its application in a group of patients at high risk for central nervous system relapse. Further evaluation of prophylactic cranial irradiation in clinical trials for regionally advanced non-small cell lung cancer is warranted.

  4. A Level-1 Tracking Trigger for the CMS upgrade using stacked silicon strip detectors and advanced pattern technologies

    NASA Astrophysics Data System (ADS)

    Boudoul, G.

    2013-01-01

    Experience at high luminosity hadrons collider experiments shows that tracking information enhances the trigger rejection capabilities while retaining high efficiency for interesting physics events. The design of a tracking based trigger for the High Luminosity LHC (HL-LHC) is an extremely challenging task, and requires the identification of high-momentum particle tracks as a part of the Level 1 Trigger. Simulation studies show that this can be achieved by correlating hits on two closely spaced silicon strip sensors, and reconstructing tracks at L1 by employing an Associative Memory approach. The progresses on the design and development of this micro-strip stacked prototype modules and the performance of few prototype detectors will be presented. Preliminary results of a simulated tracker layout equipped with stacked modules are discussed in terms of pT resolution and triggering capabilities. Finally, a discussion on the L1 architecture will be given.

  5. Dignity and Deferral Narratives as Strategies in Facilitated Technology-Based Support Groups for People with Advanced Cancer

    PubMed Central

    Street, Annette F.; Wakelin, Kate; Hordern, Amanda; Bruce, Nicola; Horey, Dell

    2012-01-01

    This paper examines the value of facilitated telephone and online support groups for palliative care. Telephone interviews were conducted with twenty people living with advanced cancer who had participated in either a telephone or online support group facilitated by the Cancer Council Victoria, Melbourne, Australia. Two dominant participant narratives emerged: a focus on dying with dignity or an interest in deferring discussion of death and dying to focus on the present. Despite the different approaches, participants found the technology-based support groups to be accessible and safe environments in which to discuss difficult topics in privacy. Technology-based strategies provide opportunities for health professionals to provide social and emotional care to more people by moving beyond individualised care and facilitate peer-to-peer support at the end of life, especially to those with specific needs. Such options are feasible for palliative care services to set up and acceptable to a group of clients, especially for younger clients or those socially or geographically isolated. PMID:22530115

  6. Advanced Stage Mucinous Adenocarcinoma of the Ovary is both Rare and Highly Lethal: A Gynecologic Oncology Group Study

    PubMed Central

    Zaino, Richard J.; Brady, Mark F.; Lele, Subodh M.; Michael, Helen; Greer, Benjamin; Bookman, Michael A.

    2010-01-01

    Background Primary mucinous adenocarcinomas of the ovary are uncommon and their biologic behavior uncertain. Retrospective studies suggest that many mucinous carcinomas diagnosed as primary to the ovary were actually metastatic from another site. A prospective randomized trial provided an opportunity to estimate the frequency of mucinous tumors, diagnostic reproducibility, and clinical outcomes. Methods A phase III trial enrolled 4000 women with stage III or IV ovarian carcinoma, treated by surgical staging and debulking, with randomization to one of five chemotherapeutic arms. Slides and pathology reports classified as primary mucinous carcinoma were reviewed independently by three pathologists. Cases were re-classified as primary or metastatic to the ovary according to two methods. Overall survival (OS) of reclassified groups was compared with each other and with that of patients with serous carcinomas. Results Forty-four cases were classified as mucinous adenocarcinoma at review. Using either method, only about one third were interpreted by the three reviewers as primary mucinous carcinomas. Reproducibility of interpretations among the reviewers was high with unanimity of opinion in 30 of the 44 (68%) cases. The median survival (MS) did not differ significantly between the groups interpreted as primary or metastatic, but the OS was significantly less than that for women with serous carcinoma (14 vs 42 months, p<0.001). Conclusion Advanced stage mucinous carcinoma of the ovary is very rare and is associated with poor OS. Many mucinous adenocarcinomas that are diagnosed as primary ovarian neoplasms appear to be metastatic to the ovary. PMID:20862744

  7. Performance of advanced a-Si/CsI-based flat-panel x-ray detectors for mammography

    NASA Astrophysics Data System (ADS)

    Albagli, Douglas; Hudspeth, Heather; Possin, George E.; Lee, Ji Ung; Granfors, Paul R.; Giambattista, Brian W.

    2003-06-01

    The GE Senographe 2000D, the first full field digital mammography system based on amorphous Silicon (a-Si) flat panel arrays and a Cesium-Iodide (CsI) scintillator, has been in clinical use for several years. The purpose of this paper is to demonstrate and quantify improvements in the detective quantum efficiency (DQE) for both typical screening and ultra-low exposure levels for this technology platform. A new figure of merit, the electronic noise factor, is introduced to explicitly quantify the influence of the electronic noise, conversion factor, modulation transfer function (MTF), and pixel pitch towards the reduction of DQE at low exposure levels. Methods to improve the DQE through an optimization of both the flat panel design and the scintillator deposition process are discussed. The results show a substantial improvement in the DQE(f) at all frequencies and demonstrate the potential for DQE(0) to exceed 80%. The combination of high DQE at ultra low exposures and the inherent fast read-out capability makes this technology platform ideal for both current clinical procedures and advanced applications that may use multiple projections (tomosynthesis) or contrast media to enhance digital mammography.

  8. Coordination of Advanced Solar Observatory (ASO) Science Working Group (SWG) for the study of instrument accommodation and operational requirements on space station

    NASA Technical Reports Server (NTRS)

    Wu, S. T.

    1989-01-01

    The objectives are to coordinate the activities of the Science Working Group (SWG) of the Advanced Solar Observatory (ASO) for the study of instruments accommodation and operation requirements on board space station. In order to facilitate the progress of the objective, two conferences were organized, together with two small group discussions.

  9. Studies of waveform requirements for intermediate mass-ratio coalescence searches with advanced gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Smith, R. J. E.; Mandel, I.; Vecchio, A.

    2013-08-01

    The coalescence of a stellar-mass compact object into an intermediate-mass black hole (intermediate mass-ratio coalescence; IMRAC) is an important astrophysical source for ground-based gravitational-wave interferometers in the so-called advanced (or second-generation) configuration. However, the ability to carry out effective matched-filter-based searches for these systems is limited by the lack of reliable waveforms. Here we consider binaries in which the intermediate-mass black hole has a mass in the range 24M⊙-200M⊙ with a stellar-mass companion having masses in the range 1.4M⊙-18.5M⊙. In addition, we constrain the mass ratios, q, of the binaries to be in the range 1/140≤q≤1/10 and we restrict our study to the case of circular binaries with nonspinning components. We investigate the relative contribution to the signal-to-noise ratio (SNR) of the three different phases of the coalescence—inspiral, merger and ringdown—using waveforms computed within the effective one-body formalism matched to numerical relativity. We show that merger and ringdown contribute to a substantial fraction of the total SNR over a large portion of the mass parameter space, although in a limited portion the SNR is dominated by the inspiral phase. We further identify three regions in the IMRAC mass space in which (i) inspiral-only searches could be performed with losses in detection rates L in the range 10%≲L≲27%, (ii) searches based on inspiral-only templates lead to a loss in detection rates in the range 27%≲L≲50%, and (iii) templates that include merger and ringdown are essential to prevent losses in detection rates greater than 50%. In addition we find that using inspiral-only templates as filters can lead to large biases in the estimates of the mass parameters of IMRACs. We investigate the effectiveness with which the inspiral-only portion of the IMRAC waveform space is covered by comparing several existing waveform families in this regime. We find that

  10. Overexpression of Receptor for Advanced Glycation End Products and High-Mobility Group Box 1 in Human Dental Pulp Inflammation

    PubMed Central

    Tancharoen, Salunya; Tengrungsun, Tassanee; Suddhasthira, Theeralaksna; Kikuchi, Kiyoshi; Vechvongvan, Nuttavun; Maruyama, Ikuro

    2014-01-01

    High mobility group box 1 (HMGB1), a nonhistone DNA-binding protein, is released into the extracellular space and promotes inflammation. HMGB1 binds to related cell signaling transduction receptors, including receptor for advanced glycation end products (RAGE), which actively participate in vascular and inflammatory diseases. The aim of this study was to examine whether RAGE and HMGB1 are involved in the pathogenesis of pulpitis and investigate the effect of Prevotella intermedia (P. intermedia) lipopolysaccharide (LPS) on RAGE and HMGB1 expression in odontoblast-like cells (OLC-1). RAGE and HMGB1 expression levels in clinically inflamed dental pulp were higher than those in healthy dental pulp. Upregulated expression of RAGE was observed in odontoblasts, stromal pulp fibroblasts-like cells, and endothelial-like cell lining human pulpitis tissue. Strong cytoplasmic HMGB1 immunoreactivity was noted in odontoblasts, whereas nuclear HMGB1 immunoreactivity was seen in stromal pulp fibroblasts-like cells in human pulpitis tissue. LPS stimulated OLC-1 cells produced HMGB1 in a dose-dependent manner through RAGE. HMGB1 translocation towards the cytoplasm and secretion from OLC-1 in response to LPS was inhibited by TPCA-1, an inhibitor of NF-κB activation. These findings suggest that RAGE and HMGB1 play an important role in the pulpal immune response to oral bacterial infection. PMID:25114379

  11. History of infrared detectors

    NASA Astrophysics Data System (ADS)

    Rogalski, A.

    2012-09-01

    This paper overviews the history of infrared detector materials starting with Herschel's experiment with thermometer on February 11th, 1800. Infrared detectors are in general used to detect, image, and measure patterns of the thermal heat radiation which all objects emit. At the beginning, their development was connected with thermal detectors, such as thermocouples and bolometers, which are still used today and which are generally sensitive to all infrared wavelengths and operate at room temperature. The second kind of detectors, called the photon detectors, was mainly developed during the 20th Century to improve sensitivity and response time. These detectors have been extensively developed since the 1940's. Lead sulphide (PbS) was the first practical IR detector with sensitivity to infrared wavelengths up to ˜3 μm. After World War II infrared detector technology development was and continues to be primarily driven by military applications. Discovery of variable band gap HgCdTe ternary alloy by Lawson and co-workers in 1959 opened a new area in IR detector technology and has provided an unprecedented degree of freedom in infrared detector design. Many of these advances were transferred to IR astronomy from Departments of Defence research. Later on civilian applications of infrared technology are frequently called "dual-use technology applications." One should point out the growing utilisation of IR technologies in the civilian sphere based on the use of new materials and technologies, as well as the noticeable price decrease in these high cost technologies. In the last four decades different types of detectors are combined with electronic readouts to make detector focal plane arrays (FPAs). Development in FPA technology has revolutionized infrared imaging. Progress in integrated circuit design and fabrication techniques has resulted in continued rapid growth in the size and performance of these solid state arrays.

  12. SNM Detection with a Large Water Cerenkov Detector

    SciTech Connect

    Dazeley, S; Bernstein, A; Bowden, N; Ouedraogo, S; Svoboda, R; Sweeny, M

    2009-06-04

    Special Nuclear Material (SNM) can either spontaneously fission, or be induced to do so. Either case results in neutron emission. Since neutrons are highly penetrating and difficult to shield, they could, potentially, be detected escaping even a well shielded cargo container. Obviously, if the shielding is sophisticated, detecting it would require a highly efficient detector with close to 4{pi} solid angle coverage. Water Cerenkov detectors may be a cost effective way to achieve that goal if it can be shown that the neutron capture signature is large enough and if sufficient background rejection can be employed as detectors get larger. In 2008 the LLNL Advanced Detector Group reported the successful detection of neutrons with a 1/4 ton gadolinium doped water Cerenkov prototype. We have now built a 4 ton version. This detector is not only bigger, it was designed with photon detection efficiency in mind from the beginning. We are employing increased photocathode coverage and more reflective walls, coated with PTFE. The increased efficiency should allow better energy resolution. We expect that the better diffusive wall reflectivity will reduce the overall dependence of the detector response on particle direction, again producing a more consistent response. We also believe that as detectors get larger, both uncorrelated and correlated backgrounds due to gamma-rays and cosmic ray interactions near the detector will increase. To prove the effectiveness of the technology we must develop new ways to reject these backgrounds while maintaining our sensitivity to SNM neutrons. Better energy resolution will enable us to reject more of the low energy gamma-ray backgrounds on this basis. Overcoming cosmic ray induced neutrons is perhaps an even larger concern as detectors get larger. Our detector is designed so that we can test various segmentation schemes - effectively dividing the detector up into smaller ones. In this presentation, we will describe our detector in detail.

  13. ISS/IDS Detector Study

    SciTech Connect

    Cervera-Villanueva, A.

    2008-02-21

    This article summarises the results obtained by the detector working group of the 'International Scooping Study' (ISS) of a future neutrino oscillations facility. Special emphasis is put on far detectors, for which some of the main issues are identified. A detector R and D strategy in the context of the 'International Design Study' (IDS) for a neutrino factory is also presented.

  14. Special Nuclear Material Detection with a Water Cherenkov based Detector

    SciTech Connect

    Sweany, M; Bernstein, A; Bowden, N; Dazeley, S; Svoboda, R

    2008-11-10

    Fission events from Special Nuclear Material (SNM), such as highly enriched uranium or plutonium, produce a number of neutrons and high energy gamma-rays. Assuming the neutron multiplicity is approximately Poissonian with an average of 2 to 3, the observation of time correlations between these particles from a cargo container would constitute a robust signature of the presence of SNM inside. However, in order to be sensitive to the multiplicity, one would require a high total efficiency. There are two approaches to maximize the total efficiency; maximizing the detector efficiency or maximizing the detector solid angle coverage. The advanced detector group at LLNL is investigating one way to maximize the detector size. We are designing and building a water Cerenkov based gamma and neutron detector for the purpose of developing an efficient and cost effective way to deploy a large solid angle car wash style detector. We report on our progress in constructing a larger detector and also present preliminary results from our prototype detector that indicates detection of neutrons.

  15. Particle Detectors

    NASA Astrophysics Data System (ADS)

    Grupen, Claus; Shwartz, Boris

    2011-09-01

    Preface to the first edition; Preface to the second edition; Introduction; 1. Interactions of particles and radiation with matter; 2. Characteristic properties of detectors; 3. Units of radiation measurements and radiation sources; 4. Accelerators; 5. Main physical phenomena used for particle detection and basic counter types; 6. Historical track detectors; 7. Track detectors; 8. Calorimetry; 9. Particle identification; 10. Neutrino detectors; 11. Momentum measurement and muon detection; 12. Ageing and radiation effects; 13. Example of a general-purpose detector: Belle; 14. Electronics; 15. Data analysis; 16. Applications of particle detectors outside particle physics; 17. Glossary; 18. Solutions; 19. Resumé; Appendixes; Index.

  16. Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists' Group.

    PubMed Central

    Aabo, K.; Adams, M.; Adnitt, P.; Alberts, D. S.; Athanazziou, A.; Barley, V.; Bell, D. R.; Bianchi, U.; Bolis, G.; Brady, M. F.; Brodovsky, H. S.; Bruckner, H.; Buyse, M.; Canetta, R.; Chylak, V.; Cohen, C. J.; Colombo, N.; Conte, P. F.; Crowther, D.; Edmonson, J. H.; Gennatas, C.; Gilbey, E.; Gore, M.; Guthrie, D.; Yeap, B. Y.

    1998-01-01

    The purpose of this systematic study was to provide an up to date and reliable quantitative summary of the relative benefits of various types of chemotherapy (non-platinum vs platinum, single-agent vs combination and carboplatin vs cisplatin) in the treatment of advanced ovarian cancer. Also, to investigate whether well-defined patient subgroups benefit more or less from cisplatin- or carboplatin-based therapy. Meta-analyses were based on updated individual patient data from all available randomized controlled trials (published and unpublished), including 37 trials, 5667 patients and 4664 deaths. The results suggest that platinum-based chemotherapy is better than non-platinum therapy, show a trend in favour of platinum combinations over single-agent platinum, and suggest that cisplatin and carboplatin are equally effective. There is no good evidence that cisplatin is more or less effective than carboplatin in any particular subgroup of patients. Images Figure 1 Figure 2 Figure 3 PMID:9836481

  17. Multisensor mine detector for peacekeeping: improved landmine detector concept (ILDC)

    NASA Astrophysics Data System (ADS)

    McFee, John E.; Carruthers, Al

    1996-05-01

    The Improved Landmine Detector Concept Project was initiated in Autumn 1994 to develop a prototype vehicle mounted mine detector for low metal content and nonmetallic mines for a peacekeeping role on roads. The system will consist of a teleoperated vehicle carrying a highly sensitive electromagnetic induction (EMI) detector, an infrared imager (IR), ground probing radar (GPR), and a thermal neutron activation (TNA) detector for confirmation. The IR, EMI and TNA detectors have been under test since 1995 and the GPR will be received in June 1996. Results of performance trials of the individual detectors are discussed. Various design configurations and their tradeoffs are discussed. Fusion of data from the detectors to reduce false alarm rate and increase probability of detection, a key element to the success of the system, is discussed. An advanced development model of the system is expected to be complete by Spring 1997.

  18. Neutron and X-ray Detectors

    SciTech Connect

    Carini, Gabriella; Denes, Peter; Gruener, Sol; Lessner, Elianne

    2012-08-01

    The Basic Energy Sciences (BES) X-ray and neutron user facilities attract more than 12,000 researchers each year to perform cutting-edge science at these state-of-the-art sources. While impressive breakthroughs in X-ray and neutron sources give us the powerful illumination needed to peer into the nano- to mesoscale world, a stumbling block continues to be the distinct lag in detector development, which is slowing progress toward data collection and analysis. Urgently needed detector improvements would reveal chemical composition and bonding in 3-D and in real time, allow researchers to watch “movies” of essential life processes as they happen, and make much more efficient use of every X-ray and neutron produced by the source The immense scientific potential that will come from better detectors has triggered worldwide activity in this area. Europe in particular has made impressive strides, outpacing the United States on several fronts. Maintaining a vital U.S. leadership in this key research endeavor will require targeted investments in detector R&D and infrastructure. To clarify the gap between detector development and source advances, and to identify opportunities to maximize the scientific impact of BES user facilities, a workshop on Neutron and X-ray Detectors was held August 1-3, 2012, in Gaithersburg, Maryland. Participants from universities, national laboratories, and commercial organizations from the United States and around the globe participated in plenary sessions, breakout groups, and joint open-discussion summary sessions. Sources have become immensely more powerful and are now brighter (more particles focused onto the sample per second) and more precise (higher spatial, spectral, and temporal resolution). To fully utilize these source advances, detectors must become faster, more efficient, and more discriminating. In supporting the mission of today’s cutting-edge neutron and X-ray sources, the workshop identified six detector research challenges

  19. RADIATION DETECTOR

    DOEpatents

    Wilson, H.N.; Glass, F.M.

    1960-05-10

    A radiation detector of the type is described wherein a condenser is directly connected to the electrodes for the purpose of performing the dual function of a guard ring and to provide capacitance coupling for resetting the detector system.

  20. NSF/ESF Workshop on Smart Structures and Advanced Sensors, Santorini Island, Greece, June 26-28, 2005: Structural Actuation and Adaptation Working Group

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Tomizuka, Masayoshi; Bergman, Lawrence; Carpenter, Bernie; Salzano, Carmine; Bairrao, rogerio; Deraemaker, Arnaud; Magonette, Georges; Rodellar, Jose; Kadirkamanathan, Visaken

    2005-01-01

    This document is a result of discussions that took place during the workshop. It describes current state of research and development (R&D) in the areas of structural actuation and adaptation in the context of smart structures and advanced sensors (SS&AS), and provides an outlook to guide future R&D efforts to develop technologies needed to build SS&AS. The discussions took place among the members of the Structural Actuation and Adaptation Working Group, as well as in general sessions including all four working groups. Participants included members of academia, industry, and government from the US and Europe, and representatives from China, Japan, and Korea.

  1. Report of the intermediate-)ital p)/sub perpendicular/ detector group: A beauty spectrometer for the SSC (superconducting super collider)

    SciTech Connect

    Foley, K.J.; Buchanan, C.D.; Morrison, R.J.; McHugh, S.W.; Witherell, M.S.; Atac, M.; Cox, B.; Purohit, M.V.; Stefanski, R.; Wagoner, D.E.

    1987-07-01

    A ''Beauty Spectrometer'' has been designed for studies of B physics at the SSC. The ultimate goal is a definitive measurement of CP violation in the B system. The spectrometer consists of two stages and occupies one side of an intermediate-luminosity interaction region. An upstream, or intermediate, stage extends from the interaction point to 14 m and covers the angular region from 57 mrad (3.3 degree) to 350 mrad (20 degree). The forward stage extends to 77 m and to angles down to 5.7 mrad. The design includes silicon microstrip detectors, conventional tracking, momentum analysis, and hadron and lepton identification. While no fundamental problems have been found, the detector must deal with unprecedented particles fluxes, trigger rates, and data rates. 11 refs., 10 figs., 5 tabs.

  2. 78 FR 39062 - Group Lotus plc; Modification of a Temporary Exemption From an Advanced Air Bag Requirement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... small manufacturers such as Lotus as of September 1, 2012. \\1\\ 78 FR 15114. After publication of Lotus's... exemption, in control of the company's dealers. See 60 FR 12281 (Mar. 6, 1995). The 50 vehicles will count... National Highway Traffic Safety Administration Group Lotus plc; Modification of a Temporary Exemption...

  3. Smoke Detector

    NASA Technical Reports Server (NTRS)

    1979-01-01

    In the photo, Fire Chief Jay Stout of Safety Harbor, Florida, is explaining to young Richard Davis the workings of the Honeywell smoke and fire detector which probably saved Richard's life and that of his teen-age brother. Alerted by the detector's warning, the pair were able to escape their burning home. The detector in the Davis home was one of 1,500 installed in Safety Harbor residences in a cooperative program conducted by the city and Honeywell Inc.

  4. Working group report on advanced high-voltage high-power and energy-storage space systems

    NASA Technical Reports Server (NTRS)

    Cohen, H. A.; Cooke, D. L.; Evans, R. W.; Hastings, D.; Jongeward, G.; Laframboise, J. G.; Mahaffey, D.; Mcintyre, B.; Pfizer, K. A.; Purvis, C.

    1986-01-01

    Space systems in the future will probably include high-voltage, high-power energy-storage and -production systems. Two such technologies are high-voltage ac and dc systems and high-power electrodynamic tethers. The working group identified several plasma interaction phenomena that will occur in the operation of these power systems. The working group felt that building an understanding of these critical interaction issues meant that several gaps in our knowledge had to be filled, and that certain aspects of dc power systems have become fairly well understood. Examples of these current collection are in quiescent plasmas and snap over effects. However, high-voltage dc and almost all ac phenomena are, at best, inadequately understood. In addition, there is major uncertainty in the knowledge of coupling between plasmas and large scale current flows in space plasmas. These gaps in the knowledge are addressed.

  5. Measuring the impact of environmental regulation on productivity growth: The case of a group of advanced countries

    SciTech Connect

    Duarte, R.; Feijoo, M.

    1997-12-31

    Recent economic literature devoted to global environmental problems for example, greenhouse gases, has focused on the emergence of international cooperation and underlying legislative incentives. International cooperation between countries is necessary in the case of global pollution because outcomes resulting from the laissez-faire equilibrium are inefficient, in that each country chooses its pollution behavior in a way that ignores the cost imposed on other countries as a result of that behavior. Voluntary cooperation between sovereign countries has been analyzed in terms of agreements between individual countries or groups of countries aimed at reducing emissions. This paper develops an approach for measuring the impact of environmental regulations on total factor productivity growth which is less restrictive than a simple growth accounting approach. We construct a model in which a group of countries seeks to expand the agreement by self-financing welfare transfers. This implies side payments to other countries in order to induce them to restrict emissions to some desired level, as a result of which a stable coalition is formed. We present some empirical research on the possibility of reaching international agreements with respect to CO{sub 2} emissions. Using data on GDP and CO{sub 2} emissions for five countries or groups of countries - Canada, USA, UE, the other OECD States and Japan- our attention is focused on patterns of energy use, changes in energy intensities through time, and the factors which underlie these changes.

  6. EGFR testing and clinical management of advanced NSCLC: a Galician Lung Cancer Group study (GGCP 048-10)

    PubMed Central

    Vázquez, Sergio; Casal, Joaquín; Afonso Afonso, Francisco Javier; Fírvida, José Luis; Santomé, Lucía; Barón, Francisco; Lázaro, Martín; Pena, Carolina; Amenedo, Margarita; Abdulkader, Ihab; González-Arenas, Carmen; Fachal, Laura; Vega, Ana

    2016-01-01

    Purpose This study aimed to assess the incidence of mutations in the epidermal growth factor receptor (EGFR) gene in non-small-cell lung cancer (NSCLC) patients in the Galician region of Spain and the clinical management and outcome of patients carrying EGFR mutations. Patients and methods All newly diagnosed advanced or metastatic NSCLC patients were screened for EGFR mutations in matched tumor samples (tissue or cytology specimens) and serum samples. Results Of 198 patients screened for EGFR mutations in tumor samples, 184 had evaluable data and, of these, 25 (13.6%) had EGFR mutations (84% sensitizing mutations). EGFR mutation was found in serum in 14 (8.1%) patients (of 174 evaluable). Compared to matched tumor tissue, serum EGFR mutation testing specificity and sensitivity were 99% and 52%, respectively. All but two patients received gefitinib. Median progression-free survival and overall survival were 10 (95% confidence interval: 4.8–15.3) months and 17.8 (95% confidence interval: 13.9–21.6) months, respectively, in patients carrying sensitizing mutations. Conclusion The incidence of EGFR mutations in Galicia is consistent with previous data in Spain. Our results also support the feasibility of EGFR testing to guide treatment decision making using tumor tissue or cytology samples, or serum samples if tumor specimens are unavailable. These findings also confirm that first-line gefitinib is an active treatment option in Caucasians with EGFR mutation-positive NSCLC. PMID:26893581

  7. Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group

    PubMed Central

    2012-01-01

    Background To evaluate the value of KRAS codon 13 mutations in patients with advanced colorectal cancer (advanced CRC) treated with oxaliplatin and fluoropyrimidines. Methods Tumor specimens from 201 patients with advanced CRC from a randomized, phase III trial comparing oxaliplatin/5-FU vs. oxaliplatin/capecitabine were retrospectively analyzed for KRAS mutations. Mutation data were correlated to response data (Overall response rate, ORR), progression-free survival (PFS) and overall survival (OS). Results 201 patients were analysed for KRAS mutation (61.2% males; mean age 64.2 ± 8.6 years). KRAS mutations were identified in 36.3% of tumors (28.8% in codon 12, 7.4% in codon 13). The ORR in codon 13 patients compared to codon 12 and wild type patients was significantly lower (p = 0.008). There was a tendency for a better overall survival in KRAS wild type patients compared to mutants (p = 0.085). PFS in all patients was not different in the three KRAS genetic groups (p = 0.72). However, we found a marked difference in PFS between patients with codon 12 and 13 mutant tumors treated with infusional 5-FU versus capecitabine based regimens. Conclusions Our data suggest that the type of KRAS mutation may be of clinical relevance under oxaliplatin combination chemotherapies without the addition of monoclonal antibodies in particular when overall response rates are important. Trial registration number 2002-04-017 PMID:22876876

  8. Optical Detectors

    NASA Astrophysics Data System (ADS)

    Tabbert, Bernd; Goushcha, Alexander

    Optical detectors are applied in all fields of human activities from basic research to commercial applications in communication, automotive, medical imaging, homeland security, and other fields. The processes of light interaction with matter described in other chapters of this handbook form the basis for understanding the optical detectors physics and device properties.

  9. Metal Detectors.

    ERIC Educational Resources Information Center

    Harrington-Lueker, Donna

    1992-01-01

    Schools that count on metal detectors to stem the flow of weapons into the schools create a false sense of security. Recommendations include investing in personnel rather than hardware, cultivating the confidence of law-abiding students, and enforcing discipline. Metal detectors can be quite effective at afterschool events. (MLF)

  10. Expression and Significance of High-Mobility Group Protein B1 (HMGB1) and the Receptor for Advanced Glycation End-Product (RAGE) in Knee Osteoarthritis

    PubMed Central

    Sun, Xue-Hui; Liu, Ying; Han, Yun; Wang, Jian

    2016-01-01

    Background This study was performed with the aim to explore the expression of high-mobility group protein B1 (HMGB1) and the receptor for advanced glycation end-product (RAGE) in knee osteoarthritis (KOA) and its clinical significance. Material/Methods A total of 108 synovial tissues selected from KOA patients were included in the experimental group. Seventy-five synovial tissues of knee joints, selected from patients who were clinically and pathologically confirmed without joint lesion, were included in the control group. The mRNA and protein expressions of HMGB1 and RAGE were determined by using RT-PCR and immunohistochemistry, respectively. Western blotting was used for measuring relative protein expression. An ROC curve was drawn to evaluate the diagnostic value of HMGB1 and RAGE for KOA. Results The positive cell number and positive expression intensity of HMGB1 and RAGE in synovial tissue was higher in the experimental group than in the control group. PI for HMGB1 and RAGE expression in KOA patients was positively correlated with clinical classification of X-ray films (P<0.05). HMGB1 and RAGE mRNA expressions, as well as relative protein expression of HMGB1 and RAGE in synovial tissue, were higher in the experimental group than in the control group (all P<0.05). The sensitivity of HMGB1 protein, RAGE protein, HMGB1 mRNA, and RAGE mRNA were 76.9%, 64.8%, 86.1%, and 64.8%, respectively; and the specificity was 100%, 96%, 74.7%, and 80%, respectively. Conclusions The protein and mRNA expressions of HMGB1 and RAGE are both increased in KOA patients, suggesting that they are involved in KOA. PMID:27320800

  11. Pivotal advances: high-mobility group box 1 protein--a cytokine with a role in cardiac repair.

    PubMed

    Germani, Antonia; Limana, Federica; Capogrossi, Maurizio C

    2007-01-01

    The nuclear protein high-mobility group box 1 (HMGB1) has been largely characterized for its role in inflammation. However, HMGB1 released by inflammatory cells, as well as by necrotic cells, may also act as a signal of tissue damage and participate in tissue repair by recruiting stem cells to the injury site. The emergence of this function has focused the interest on HMGB1 as a molecule with an active role in tissue regeneration. We recently demonstrated that HMGB1 administration in a mouse model of myocardial infarction activates cardiac stem cells and promotes their differentiation into cardiomyocytes. The regenerative effect results in the improvement of cardiac function. In this review, we highlight the beneficial role of HMGB1 and discuss growth factor-based therapeutic approaches for the treatment of myocardial infarction. PMID:16940333

  12. ZnCdMgSe as a Materials Platform for Advanced Photonic Devices: Broadband Quantum Cascade Detectors and Green Semiconductor Disk Lasers

    NASA Astrophysics Data System (ADS)

    De Jesus, Joel

    The ZnCdMgSe family of II-VI materials has unique and promising characteristics that may be useful in practical applications. For example they can be grown lattice matched to InP substrates with lattice matched bandgaps that span from 2.1 to 3.5 eV, they can be successfully doped n-type, have a large conduction band offset (CBO) with no intervalley scattering present when strained, they have lower average phonon energies, and the InP lattice constant lies in the middle of the ZnSe and CdSe binaries compounds giving room to experiment with tensile and compressive stress. However they have not been studied in detail for use in practical devices. Here we have identified two types of devices that are being currently developed that benefit from the ZnCdMgSe-based material properties. These are the intersubband (ISB) quantum cascade (QC) detectors and optically pumped semiconductor lasers that emit in the visible range. The paucity for semiconductor lasers operating in the green-orange portion of the visible spectrum can be easily overcome with the ZnCdMgSe materials system developed in our research. The non-strain limited, large CBO available allows to expand the operating wavelength of ISB devices providing shorter and longer wavelengths than the currently commercially available devices. This property can also be exploited to develop broadband room temperature operation ISB detectors. The work presented here focused first on using the ZnCdMgSe-based material properties and parameter to understand and predict the interband and intersubband transitions of its heterostructures. We did this by studying an active region of a QC device by contactless electroreflectance, photoluminescence, FTIR transmittance and correlating the measurements to the quantum well structure by transfer matrix modeling. Then we worked on optimizing the ZnCdMgSe material heterostructures quality by studying the effects of growth interruptions on their optical and optoelectronic properties of

  13. Working Group Report: Sensors

    SciTech Connect

    Artuso, M.; et al.,

    2013-10-18

    Sensors play a key role in detecting both charged particles and photons for all three frontiers in Particle Physics. The signals from an individual sensor that can be used include ionization deposited, phonons created, or light emitted from excitations of the material. The individual sensors are then typically arrayed for detection of individual particles or groups of particles. Mounting of new, ever higher performance experiments, often depend on advances in sensors in a range of performance characteristics. These performance metrics can include position resolution for passing particles, time resolution on particles impacting the sensor, and overall rate capabilities. In addition the feasible detector area and cost frequently provides a limit to what can be built and therefore is often another area where improvements are important. Finally, radiation tolerance is becoming a requirement in a broad array of devices. We present a status report on a broad category of sensors, including challenges for the future and work in progress to solve those challenges.

  14. Analysis of laser jamming to satellite-based detector

    NASA Astrophysics Data System (ADS)

    Wang, Si-wen; Guo, Li-hong; Guo, Ru-hai

    2009-07-01

    The reconnaissance satellite, communication satellite and navigation satellite used in the military applications have played more and more important role in the advanced technique wars and already become the significant support and aid system for military actions. With the development of all kinds of satellites, anti-satellite laser weapons emerge as the times require. The experiments and analyses of laser disturbing CCD (charge coupled detector) in near ground have been studied by many research groups, but their results are not suitable to the case that using laser disturbs the satellite-based detector. Because the distance between the satellite-based detector and the ground is very large, it is difficult to damage it directly. However the optical receive system of satellite detector has large optical gain, so laser disturbing satellite detector is possible. In order to determine its feasibility, the theoretical analyses and experimental study are carried out in the paper. Firstly, the influence factors of laser disturbing satellite detector are analyzed in detail, which including laser power density on the surface of the detector after long distance transmission, and laser power density threshold for disturbing etc. These factors are not only induced by the satellite orbit, but dependence on the following parameters: laser average power in the ground, laser beam quality, tracing and aiming precision and atmospheric transmission. A calculation model is developed by considering all factors which then the power density entering into the detector can be calculated. Secondly, the laser disturbing experiment is performed by using LD (laser diode) with the wavelength 808 nm disturbing CCD 5 kilometer away, which the disturbing threshold value is obtained as 3.55×10-4mW/cm2 that coincides with other researcher's results. Finally, using the theoretical model, the energy density of laser on the photosensitive surface of MSTI-3 satellite detector is estimated as about 100m

  15. MS Detectors

    SciTech Connect

    Koppenaal, David W.; Barinaga, Charles J.; Denton, M Bonner B.; Sperline, Roger P.; Hieftje, Gary M.; Schilling, G. D.; Andrade, Francisco J.; Barnes IV., James H.

    2005-11-01

    Good eyesight is often taken for granted, a situation that everyone appreciates once vision begins to fade with age. New eyeglasses or contact lenses are traditional ways to improve vision, but recent new technology, i.e. LASIK laser eye surgery, provides a new and exciting means for marked vision restoration and improvement. In mass spectrometry, detectors are the 'eyes' of the MS instrument. These 'eyes' have also been taken for granted. New detectors and new technologies are likewise needed to correct, improve, and extend ion detection and hence, our 'chemical vision'. The purpose of this report is to review and assess current MS detector technology and to provide a glimpse towards future detector technologies. It is hoped that the report will also serve to motivate interest, prompt ideas, and inspire new visions for ion detection research.

  16. Advanced light element and low energy X-ray line analysis using Energy Dispersive Spectrometry (EDS) with Silicon Drift Detectors (SDD)

    NASA Astrophysics Data System (ADS)

    Salge, T.; Palasse, L.; Berlin, J.; Hansen, B.; Terborg, R.; Falke, M.

    2013-12-01

    Introduction: Characterization at the micro- to nano-scale is crucial for understanding many processes in earth, planetary, material and biological sciences. The composition of thin electron transparent samples can be analyzed in the nm-range using transmission electron microscopes (TEM) or, specific sample holders provided, in the field emission scanning electron microscope (FE-SEM). Nevertheless both methods often require complex sample preparation. An alternative method is to analyze bulk samples with a FE-SEM. In order to decrease the excitation volume for generated X-rays, low accelerating voltages (HV<10) are required. Consequently, only low to intermediate energy X-ray lines can be evaluated and many peak overlaps have to be deconvoluted since the high energy range is not available. Methods: A BRUKER Quantax EDS system with an XFlash Silicon Drift Detector acquired EDS spectra in spectrum images. To separate overlapping peaks, an extended atomic database [1] was used. For single channel EDS the electron beam current, solid angle, take-off angle and exposure time can be optimized to investigate the element composition. Multiple SDD setups ensure an even higher efficiency and larger collection angles for the X-ray analysis than single channel detectors. Shadowing effects are minimized in element distribution maps so that samples can be investigated quickly and sometimes in a close to natural state, with little preparation. A new type of EDS detector, the annular four channel SDD (XFlash 5060F), is placed between the pole piece and sample. It covers a very large solid angle (1.1 sr) and allows sufficient data collection at low beam currents on beam sensitive samples with substantial surface topography. Examples of applications: Results demonstrate that SDD-based EDS analysis contributes essential information on the structure at the micro- to nano scale of the investigated sample types. These include stardust analogue impact experiments [2], Chicxulub asteroid

  17. Combination of Trabectedin and Gemcitabine for Advanced Soft Tissue Sarcomas: Results of a Phase I Dose Escalating Trial of the German Interdisciplinary Sarcoma Group (GISG)

    PubMed Central

    Kasper, Bernd; Reichardt, Peter; Pink, Daniel; Sommer, Michaela; Mathew, Monika; Rauch, Geraldine; Hohenberger, Peter

    2015-01-01

    Background: Evaluation of the potential efficacy and safety of combination therapies for advanced soft tissue sarcomas (STS) has increased substantially after approval of trabectedin and pazopanib. Trabectedin’s introduction in Europe in 2007 depended mainly on its activity in so-called L-sarcomas (liposarcoma and leiomyosarcoma); combination of trabectedin with other chemotherapies used in STS seems of particular interest. Methods: We initiated within the German Interdisciplinary Sarcoma Group (GISG) a phase I dose escalating trial evaluating the combination of trabectedin and gemcitabine in patients with advanced and/or metastatic L-sarcomas (GISG-02; ClinicalTrials.gov NCT01426633). Patients were treated with increasing doses of trabectedin and gemcitabine. The primary endpoint was to determine the maximum tolerated dose. Results: Five patients were included in the study. Two patients were treated on dose level 1 comprising trabectedin 0.9 mg/m2 on day 1 and gemcitabine 700 mg/m2 on days 1 + 8, every 3 weeks. Due to dose-limiting toxicity (DLT) in both patients (elevated transaminases and thrombocytopenia), an additional three patients were treated on dose level −1 with trabectedin 0.7 mg/m2 plus gemcitabine 700 mg/m2. Of these three patients, two demonstrated another DLT; therefore, the trial was stopped and none of the dose levels could be recommended for phase II testing. Conclusion: The GISG-02 phase I study was stopped with the conclusion that the combination of gemcitabine and trabectedin is generally not recommended for the treatment of patients with advanced and/or metastatic leiomyosarcoma or liposarcoma. Also, this phase I study strongly supports the necessity for careful evaluation of combination therapies. PMID:25591040

  18. Survey of a Pelvic Health Physiotherapy Community of Practice: A Pilot Study to Gain Member Input to Help Sustain and Advance the Group

    PubMed Central

    MacIntyre, Donna L.

    2015-01-01

    ABSTRACT Purpose: To gather input and perspectives from members of the Calgary Pelvic Health Physiotherapists' Community of Practice (PHPT CoP) to ensure common goals that help sustain and advance the group. Method: An online survey grounded in CoP theory was used to elicit feedback from 23 PHPTs. Descriptive statistics summarized survey results. Results: The response rate was 96%; all respondents worked in women's pelvic health. Respondents expressed interest in continuing regular face-to-face meetings, a speaker series, case studies, and connecting with other PHPTs. Conclusion: The findings suggest continuation of regular meetings, with a focus on clinical skill development, and an annual Alberta PHPT conference. Members of this community of practice seek a strategy to promote PHPT to the public and develop referral sources. PMID:25931649

  19. Risk of advanced gastric precancerous lesions in Helicobacter pylori infected subjects is influenced by ABO blood group and cagA status

    PubMed Central

    Rizzato, Cosmeri; Kato, Ikuko; Plummer, Martyn; Muñoz, Nubia; Stein, Angelika; van Doorn, Leen Jan; Franceschi, Silvia; Canzian, Federico

    2013-01-01

    A higher incidence of stomach cancer in ABO blood type A individuals than in those with blood type O has been known for a long time. We studied this association in relation to Helicobacter pylori (Hp) of different cagA status. For this study we used baseline gastric histopathology data and DNAs from frozen gastric biopsies of 2077 subjects enrolled in a chemoprevention trial for gastric precancerous lesions in Venezuela. We analyzed 6 single nucleotide polymorphisms in the ABO gene and we assessed the presence of the Hp cagA gene. Odds ratios for risk of advanced precancerous gastric lesions were calculated using individuals with normal gastric epithelium or non-atrophic gastritis as a reference. Among individuals carrying a cagA negative Hp infection or no Hp infection, those with blood type A had a lower risk of intestinal metaplasia and dysplasia than those with blood type O (OR=0.60; 95% CI 0.38-0.94). In carriers of cagA positive Hp strains, individuals with blood type A had a higher risk of intestinal metaplasia or dysplasia than those with blood type O (OR=1.42, 95% CI 1.09-1.86) and a higher risk if compared with subjects carrying cagA− strain and non-A blood group (OR=3.82, 95%CI=2.80-5.20). The interaction between Hp cagA status and blood type was statistically significant (P=0.0006). We showed that SNPs in the ABO gene, predictive of ABO blood groups, are associated with risk of advanced precancerous gastric lesions in individuals infected with Hp, but the assessment of the risk is strictly dependent on cagA status. PMID:23319424

  20. Facilitating advance care planning with ethnically diverse groups of frail, low-income elders in the USA: perspectives of care managers on challenges and recommendations.

    PubMed

    Kwak, Jung; Ko, Eunjeong; Kramer, Betty J

    2014-03-01

    This study examined care managers' perspectives on facilitating advance care planning (ACP) with ethnically diverse elders enrolled in a managed long-term care programme that coordinates medical and long-term care for frail, poor elders in the USA. Seven in-depth interviews and two focus groups were conducted with 24 lead supervisors and care managers of care management teams between July and August 2008; data were analysed with qualitative thematic analysis method. Participants identified four main sources of challenges: death and dying are taboo discussion topics; the dying process is beyond human control; family and others hold decision-making responsibility; and planning for death and dying is a foreign concept. Participants' recommendations to address these challenges were to develop trust with elders over time; cultivate cultural knowledge and sensitivity to respect value orientations; promote designating a healthcare proxy; recognise and educate families and community leaders as critical partners in ACP and provide practical support as needed throughout the illness experience. These findings suggest important practice implications for care managers working with increasingly diverse cultural groups of elders at the end of life. PMID:24495270

  1. The status of laser interferometer gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Raab, F. J.; Ligo Scientific Collaboration

    2006-05-01

    There has been a rapid advance in the sensitivity of broadband searches for gravitational waves, using an international network of kilometer-scale laser interferometers. The LIGO detectors in North America, the GEO600 detector in Germany and the TAMA300 detector in Japan have conducted searches for gravitational waves covering a frequency range from below 100 Hz up to many kHz. These detectors and the VIRGO detector in Italy are in a mature state of commissioning and technology development for a generation of more advanced detectors is ongoing.

  2. PHASE DETECTOR

    DOEpatents

    Kippenhan, D.O.

    1959-09-01

    A phase detector circuit is described for use at very high frequencies of the order of 50 megacycles. The detector circuit includes a pair of rectifiers inverted relative to each other. One voltage to be compared is applied to the two rectifiers in phase opposition and the other voltage to be compared is commonly applied to the two rectifiers. The two result:ng d-c voltages derived from the rectifiers are combined in phase opposition to produce a single d-c voltage having amplitude and polarity characteristics dependent upon the phase relation between the signals to be compared. Principal novelty resides in the employment of a half-wave transmission line to derive the phase opposing signals from the first voltage to be compared for application to the two rectifiers in place of the transformer commonly utilized for such purpose in phase detector circuits for operation at lower frequency.

  3. MAMA Detector

    NASA Technical Reports Server (NTRS)

    Bowyer, Stuart

    1998-01-01

    Work carried out under this grant led to fundamental discoveries and over one hundred publications in the scientific literature. Fundamental developments in instrumentation were made including all the instrumentation on the EUVE satellite, the invention of a whole new type of grazing instrument spectrometer and the development of fundamentally new photon counting detectors including the Wedge and Strip used on EUVE and many other missions and the Time Delay detector used on OREFUS and FUSE. The Wedge and Strip and Time Delay detectors were developed under this grant for less than two million dollars and have been used in numerous missions most recently for the FUSE mission. In addition, a fundamentally new type of diffuse spectrometer has been developed under this grant which has been used in instrumentation on the MMSAT spacecraft and the Lewis spacecraft. Plans are underway to use this instrumentation on several other missions as well.

  4. Hydrogen detector

    DOEpatents

    Kanegae, Naomichi; Ikemoto, Ichiro

    1980-01-01

    A hydrogen detector of the type in which the interior of the detector is partitioned by a metal membrane into a fluid section and a vacuum section. Two units of the metal membrane are provided and vacuum pipes are provided independently in connection to the respective units of the metal membrane. One of the vacuum pipes is connected to a vacuum gauge for static equilibrium operation while the other vacuum pipe is connected to an ion pump or a set of an ion pump and a vacuum gauge both designed for dynamic equilibrium operation.

  5. Microwave detector

    DOEpatents

    Meldner, Heiner W.; Cusson, Ronald Y.; Johnson, Ray M.

    1986-01-01

    A microwave detector (10) is provided for measuring the envelope shape of a microwave pulse comprised of high-frequency oscillations. A biased ferrite (26, 28) produces a magnetization field flux that links a B-dot loop (16, 20). The magnetic field of the microwave pulse participates in the formation of the magnetization field flux. High-frequency insensitive means (18, 22) are provided for measuring electric voltage or current induced in the B-dot loop. The recorded output of the detector is proportional to the time derivative of the square of the envelope shape of the microwave pulse.

  6. Microwave detector

    DOEpatents

    Meldner, H.W.; Cusson, R.Y.; Johnson, R.M.

    1985-02-08

    A microwave detector is provided for measuring the envelope shape of a microwave pulse comprised of high-frequency oscillations. A biased ferrite produces a magnetization field flux that links a B-dot loop. The magnetic field of the microwave pulse participates in the formation of the magnetization field flux. High-frequency insensitive means are provided for measuring electric voltage or current induced in the B-dot loop. The recorded output of the detector is proportional to the time derivative of the square of the envelope shape of the microwave pulse.

  7. Detectors in Extreme Conditions

    SciTech Connect

    Blaj, G.; Carini, G.; Carron, S.; Haller, G.; Hart, P.; Hasi, J.; Herrmann, S.; Kenney, C.; Segal, J.; Tomada, A.

    2015-08-06

    Free Electron Lasers opened a new window on imaging the motion of atoms and molecules. At SLAC, FEL experiments are performed at LCLS using 120Hz pulses with 1012 - 1013 photons in 10 femtoseconds (billions of times brighter than the most powerful synchrotrons). This extreme detection environment raises unique challenges, from obvious to surprising. Radiation damage is a constant threat due to accidental exposure to insufficiently attenuated beam, focused beam and formation of ice crystals reflecting the beam onto the detector. Often high power optical lasers are also used (e.g., 25TW), increasing the risk of damage or impeding data acquisition through electromagnetic pulses (EMP). The sample can contaminate the detector surface or even produce shrapnel damage. Some experiments require ultra high vacuum (UHV) with strict design, surface contamination and cooling requirements - also for detectors. The setup is often changed between or during experiments with short turnaround times, risking mechanical and ESD damage, requiring work planning, training of operators and sometimes continuous participation of the LCLS Detector Group in the experiments. The detectors used most often at LCLS are CSPAD cameras for hard x-rays and pnCCDs for soft x-rays.

  8. Phase II trial of fluorouracil and recombinant interferon alfa-2a in patients with advanced colorectal carcinoma: an Eastern Cooperative Oncology Group study.

    PubMed

    Wadler, S; Lembersky, B; Atkins, M; Kirkwood, J; Petrelli, N

    1991-10-01

    In a pilot clinical trial, treatment of patients with advanced colorectal carcinoma with the combination of fluorouracil (5FU) and recombinant interferon alfa-2a (IFN) resulted in objective tumor regression in 62% of patients. To confirm these findings in a multiinstitutional setting, a phase II clinical trial was initiated by the Eastern Cooperative Oncology Group (ECOG) in 1989. The treatment regimen was identical to that used in the earlier study: 5FU 750 mg/m2/d for 5 days as a continuous infusion followed by weekly outpatient bolus therapy and IFN 9MU subcutaneously beginning day 1 and administered three times per week. Doses were modified for gastrointestinal, hematologic, and neurologic toxicity and for fatigue, similarly to those used in the previous pilot trial. Thirty-eight patients were registered; 36 are evaluable for response (one lost to follow-up and one with nonmeasurable disease). All patients had metastatic or locally recurrent disease beyond the scope of resection; 31 of 38 had liver metastases, and 20 of 38 had two or more sites of involvement. Eight patients had grade 4 toxicities, including sepsis (nonneutropenic) (one), watery diarrhea (two), and granulocytopenia (six). Grade 3 neurologic toxicities were observed in two (5%) patients and included slurred speech and gait disturbance. Objective response was 42% (95% confidence interval [Cl], 27% to 58%), including one clinical complete responder and 14 partial responders. Among the responding patients, the median time to treatment failure was 8 months. Two patients remain on treatment at 10+ and 16+ months: median survival has not been reached. The results of this multiinstitutional trial suggest that the addition of IFN to 5FU enhances the objective response rates achieved in patients with advanced colorectal carcinoma and that the toxicities of this regimen are acceptable. PMID:1919631

  9. Vertex detectors

    SciTech Connect

    Lueth, V.

    1992-07-01

    The purpose of a vertex detector is to measure position and angles of charged particle tracks to sufficient precision so as to be able to separate tracks originating from decay vertices from those produced at the interaction vertex. Such measurements are interesting because they permit the detection of weakly decaying particles with lifetimes down to 10{sup {minus}13} s, among them the {tau} lepton and charm and beauty hadrons. These two lectures are intended to introduce the reader to the different techniques for the detection of secondary vertices that have been developed over the past decades. The first lecture includes a brief introduction to the methods used to detect secondary vertices and to estimate particle lifetimes. It describes the traditional technologies, based on photographic recording in emulsions and on film of bubble chambers, and introduces fast electronic registration of signals derived from scintillating fibers, drift chambers and gaseous micro-strip chambers. The second lecture is devoted to solid state detectors. It begins with a brief introduction into semiconductor devices, and then describes the application of large arrays of strip and pixel diodes for charged particle tracking. These lectures can only serve as an introduction the topic of vertex detectors. Time and space do not allow for an in-depth coverage of many of the interesting aspects of vertex detector design and operation.

  10. Large Format Detector Arrays for Astrophysics

    NASA Technical Reports Server (NTRS)

    Moseley, Harvey

    2006-01-01

    Improvements in detector design and advances in fabrication techniques has resulted in devices which can reach fundamental sensitivity limits in many cases. Many pressing astrophysical questions require large arrays of such sensitive detectors. I will describe the state of far infrared through millimeter detector development at NASA/GSFC, the design and production of large format arrays, and the initial deployment of these powerful new tools.

  11. The GEO 600 gravitational wave detector

    NASA Astrophysics Data System (ADS)

    Willke, B.; Aufmuth, P.; Aulbert, C.; Babak, S.; Balasubramanian, R.; Barr, B. W.; Berukoff, S.; Bose, S.; Cagnoli, G.; Casey, M. M.; Churches, D.; Clubley, D.; Colacino, C. N.; Crooks, D. R. M.; Cutler, C.; Danzmann, K.; Davies, R.; Dupuis, R.; Elliffe, E.; Fallnich, C.; Freise, A.; Goßler, S.; Grant, A.; Grote, H.; Heinzel, G.; Heptonstall, A.; Heurs, M.; Hewitson, M.; Hough, J.; Jennrich, O.; Kawabe, K.; Kötter, K.; Leonhardt, V.; Lück, H.; Malec, M.; McNamara, P. W.; McIntosh, S. A.; Mossavi, K.; Mohanty, S.; Mukherjee, S.; Nagano, S.; Newton, G. P.; Owen, B. J.; Palmer, D.; Papa, M. A.; Plissi, M. V.; Quetschke, V.; Robertson, D. I.; Robertson, N. A.; Rowan, S.; Rüdiger, A.; Sathyaprakash, B. S.; Schilling, R.; Schutz, B. F.; Senior, R.; Sintes, A. M.; Skeldon, K. D.; Sneddon, P.; Stief, F.; Strain, K. A.; Taylor, I.; Torrie, C. I.; Vecchio, A.; Ward, H.; Weiland, U.; Welling, H.; Williams, P.; Winkler, W.; Woan, G.; Zawischa, I.

    2002-04-01

    The GEO 600 laser interferometer with 600 m armlength is part of a worldwide network of gravitational wave detectors. Due to the use of advanced technologies like multiple pendulum suspensions with a monolithic last stage and signal recycling, the anticipated sensitivity of GEO 600 is close to the initial sensitivity of detectors with several kilometres armlength. This paper describes the subsystems of GEO 600, the status of the detector by September 2001 and the plans towards the first science run.

  12. Patient Reported Outcomes in a Practice Changing Randomized Trial of Bevacizumab in the Treatment of Advanced Cervical Cancer: An NRG Oncology/Gynecologic Oncology Group Study

    PubMed Central

    Penson, Richard T.; Huang, Helen Q.; Wenzel, Lari B.; Monk, Bradley J.; Stockman, Sharon; Long, Harry J.; Ramondetta, Lois M.; Landrum, Lisa M.; Oaknin, Ana; Reid, Thomas J.A.; Leitao, Mario M.; Method, Michael; Michael, Helen; Tewari, Krishnansu S.

    2015-01-01

    Background To analyze patient reported outcomes (PROs) in GOG 240, the practice-changing, randomized phase 3 trial that concluded that chemotherapy (cisplatin-paclitaxel or topotecan-paclitaxel) plus bevacizumab significantly improves overall survival (OS), progression-free survival (PFS), and response rates compared to chemotherapy alone in advanced cervical cancer. Trial registration number: NCT00803062. Methods Patients were assessed pre-cycle 1, 2, and 5 and at 6 and 9 months post-cycle 1 with the Functional Assessment of Cancer Therapy-Cervix Trial Outcome Index (FACT-Cx TOI), and items from the FACT/GOG-Neurotoxicity (Ntx) subscale, and a worst pain item from the Brief Pain Inventory (BPI). Differences in FACT-Cx TOI scores were assessed using a linear mixed model adjusting for baseline score and age. A mixed effects mixed distributions model was fitted to evaluate treatment differences of likelihood to report neurotoxicity and pain, and severity of these symptoms, once reported. The association between baseline health-related quality of life and survival was analyzed using Cox proportional hazards models. Findings Among 390 evaluable patients, PRO completion rates declined from 96% (baseline) to 63% (9 months post-cycle 1). Completion rates were not statistically different among treatment regimens (p=0.67). Patients receiving chemotherapy plus bevacizumab reported 1.2 points lower on average (98.75% CI: −4.1, 1.7; p=0.30) in the FACT-Cx TOI scores than those with chemotherapy alone. Patients treated with chemotherapy plus bevacizumab were less likely to report neurotoxicty (overall odds ratio: 0.58; 98.75% CI: 0.17, 0.98; p=0.01). Severity of neurotoxic symptoms did not differ between the two groups (p=0.69). Both groups had similar odds of complaining of pain (odds ratio=0.96; 95% CI: 0.39, 1.52; p=0.78) and reported similar severity of pain (p=0.1). For the entire population, the baseline FACT-Cx TOI score was significantly associated with OS (HR 0

  13. Kansas Advanced Semiconductor Project

    SciTech Connect

    Baringer, P.; Bean, A.; Bolton, T.; Horton-Smith, G.; Maravin, Y.; Ratra, B.; Stanton, N.; von Toerne, E.; Wilson, G.

    2007-09-21

    KASP (Kansas Advanced Semiconductor Project) completed the new Layer 0 upgrade for D0, assumed key electronics projects for the US CMS project, finished important new physics measurements with the D0 experiment at Fermilab, made substantial contributions to detector studies for the proposed e+e- international linear collider (ILC), and advanced key initiatives in non-accelerator-based neutrino physics.

  14. Low-Power Multi-Aspect Space Radiation Detector System

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave; Freeman, Jon C.; Burkebile, Stephen P.

    2012-01-01

    The advanced space radiation detector development team at NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of all of these detector technologies will result in an improved detector system in comparison to existing state-of-the-art (SOA) instruments for the detection and monitoring of the deep space radiation field.

  15. Quality-of-Life Comparisons in a Randomized Trial of Interval Secondary Cytoreduction in Advanced Ovarian Carcinoma: A Gynecologic Oncology Group Study

    PubMed Central

    Wenzel, Lari; Huang, Helen Q.; Monk, Bradley J.; Rose, Peter G.; Cella, David

    2016-01-01

    Purpose To compare self-reported quality of life (QOL) in patients who did versus did not undergo interval secondary cytoreduction after initial surgery and combination chemotherapy for advanced ovarian cancer and to assess the association between baseline QOL scores and survival. Patients and Methods Consenting patients participating in a Gynecologic Oncology Group (GOG) phase III treatment trial (GOG 152) completed the Functional Assessment of Cancer Therapy–Ovarian (FACT-O) questionnaire and treatment-specific supplemental questions at the third and sixth chemotherapy cycles and at 6 and 12 months after starting treatment. Results For all patients, QOL decreased approximately 1 unit from the first to second assessment. Significant improvement observed at 6 months (P < .001) was sustained at 12 months, with no appreciable between-group difference. The baseline FACT-O score was associated with overall survival (P = .048) but not progression-free survival. Less neurotoxicity was reported among patients who did (38.4%) versus did not (54.0%) undergo interval secondary cytoreduction at the third assessment (P = .005), and older patients experienced more long-term effects. Conclusion This is the first multicenter randomized trial in ovarian cancer to longitudinally examine self-reported QOL and establish a predictive value of baseline QOL on survival, attributed primarily to the lowest-scoring quartile. Although interval secondary cytoreduction resulted in no notable long-term difference, a clinically significant improvement was seen in both arms at 6 and 12 months after starting therapy. Interestingly, there were fewer complaints of neurotoxicity at 6 months among patients who did versus did not undergo interval secondary cytoreduction. PMID:16110020

  16. Barriers to Advance Care Planning in Cancer, Heart Failure and Dementia Patients: A Focus Group Study on General Practitioners' Views and Experiences

    PubMed Central

    De Vleminck, Aline; Pardon, Koen; Beernaert, Kim; Deschepper, Reginald; Houttekier, Dirk; Van Audenhove, Chantal; Deliens, Luc; Vander Stichele, Robert

    2014-01-01

    Background The long-term and often lifelong relationship of general practitioners (GPs) with their patients is considered to make them the ideal initiators of advance care planning (ACP). However, in general the incidence of ACP discussions is low and ACP seems to occur more often for cancer patients than for those with dementia or heart failure. Objective To identify the barriers, from GPs' perspective, to initiating ACP and to gain insight into any differences in barriers between the trajectories of patients with cancer, heart failure and dementia. Method Five focus groups were held with GPs (n = 36) in Flanders, Belgium. The focus group discussions were transcribed verbatim and analyzed using the method of constant comparative analysis. Results Three types of barriers were distinguished: barriers relating to the GP, to the patient and family and to the health care system. In cancer patients, a GP's lack of knowledge about treatment options and the lack of structural collaboration between the GP and specialist were expressed as barriers. Barriers that occured more often with heart failure and dementia were the lack of GP familiarity with the terminal phase, the lack of key moments to initiate ACP, the patient's lack of awareness of their diagnosis and prognosis and the fact that patients did not often initiate such discussions themselves. The future lack of decision-making capacity of dementia patients was reported by the GPs as a specific barrier for the initiation of ACP. Conclusion The results of our study contribute to a better understanding of the factors hindering GPs in initiating ACP. Multiple barriers need to be overcome, of which many can be addressed through the development of practical guidelines and educational interventions. PMID:24465450

  17. Metformin protects against hyperglycemia-induced cardiomyocytes injury by inhibiting the expressions of receptor for advanced glycation end products and high mobility group box 1 protein.

    PubMed

    Zhang, Ting; Hu, Xiaorong; Cai, Yuli; Yi, Bo; Wen, Zhongyuan

    2014-03-01

    Metformin (MET), an anti-diabetic oral drug with antioxidant properties, has been proved to provide cardioprotective effects in patients with diabetic disease. However, the mechanism is unclear. This study aimd to investigate the effects of MET on the expressions of receptor for advanced glycation end products (RAGE) and high mobility group box 1 protein (HMGB1) in hyperglycemia-treated neonatal rat ventricular myocytes. Cardiocytes were prepared and cultured with high glucose and different concentrations of MET. The expressions of RAGE and HMGB1 were evaluated by Western blot analysis. The superoxide dismutase (SOD), malondialdehyde (MDA), tumor necrosis factor-α (TNF-α), lactate dehydrogenase (LDH) and creatine kinase (CK) were measured. After 12 h-incubation, MET significantly inhibited the increase of MDA, TNF-α, LDH and CK levels induced by high glucose, especially at the 5 × 10(-5) to 10(-4 )mol/L concentrations while inhibiting the decrease of SOD level. Meanwhile, RAGE and HMGB1 expression were significantly increased induced by hyperglycaemia for 24 h (P < 0.05). MET inhibited the expressions of RAGE and HMGB1 in a dose-dependent manner, especially at the 5 × 10(-5) to 10(-4 )mol/L concentrations (P < 0.05). In conclusion, our study suggested that MET could reduce hyperglycemia-induced cardiocytes injury by inhibiting the expressions of RAGE and HMGB1. PMID:24420848

  18. Impact of Serum High Mobility Group Box 1 and Soluble Receptor for Advanced Glycation End-Products on Subclinical Atherosclerosis in Patients with Granulomatosis with Polyangiitis

    PubMed Central

    de Souza, Alexandre W. S.; de Leeuw, Karina; van Timmeren, Mirjan M.; Limburg, Pieter C.; Stegeman, Coen A.; Bijl, Marc; Westra, Johanna; Kallenberg, Cees G. M.

    2014-01-01

    The objective of this study was to evaluate whether levels of high mobility group box 1 (HMGB1) in granulomatosis with polyangiitis (GPA) patients are associated with carotid atherosclerosis, related to levels of soluble receptor for advanced glycation end-products (sRAGE) and influenced by immunosuppressive or lipid-lowering therapy. Twenty-three GPA patients and 20 controls were evaluated for HMGB1- and sRAGE levels and for carotid atherosclerosis using ultrasound to determine intima-media thickness (IMT). In vitro the effect of atorvastatin on the production of HMGB1 by lipopolysaccharide (LPS)-stimulated human umbilical vein endothelial cells (HUVEC) was assessed. Serum HMGB1 and sRAGE levels did not differ between patients and controls. A negative correlation was found between sRAGE and maximum IMT but HMGB1 and carotid IMT were not related. HMGB1 levels were reduced in GPA patients on statins and prednisolone. In vitro, atorvastatin reduced HMGB1 levels in supernatants of activated HUVEC. In conclusion, carotid IMT is inversely correlated with sRAGE levels but not with HMGB1 levels. Statins and prednisolone are associated with reduced serum HMGB1 levels and atorvastatin decreases HMGB1 release by activated HUVEC in vitro, indicating an additional anti-inflammatory effect of statins. PMID:24776932

  19. Angle detector

    NASA Technical Reports Server (NTRS)

    Parra, G. T. (Inventor)

    1978-01-01

    An angle detector for determining a transducer's angular disposition to a capacitive pickup element is described. The transducer comprises a pendulum mounted inductive element moving past the capacitive pickup element. The capacitive pickup element divides the inductive element into two parts L sub 1 and L sub 2 which form the arms of one side of an a-c bridge. Two networks R sub 1 and R sub 2 having a plurality of binary weighted resistors and an equal number of digitally controlled switches for removing resistors from the networks form the arms of the other side of the a-c bridge. A binary counter, controlled by a phase detector, balances the bridge by adjusting the resistance of R sub 1 and R sub 2. The binary output of the counter is representative of the angle.

  20. Flame Detector

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Scientific Instruments, Inc. has now developed a second generation, commercially available instrument to detect flames in hazardous environments, typically refineries, chemical plants and offshore drilling platforms. The Model 74000 detector incorporates a sensing circuit that detects UV radiation in a 100 degree conical field of view extending as far as 250 feet from the instrument. It operates in a bandwidth that makes it virtually 'blind' to solar radiation while affording extremely high sensitivity to ultraviolet flame detection. A 'windowing' technique accurately discriminates between background UV radiation and ultraviolet emitted from an actual flame, hence the user is assured of no false alarms. Model 7410CP is a combination controller and annunciator panel designed to monitor and control as many as 24 flame detectors. *Model 74000 is no longer being manufactured.

  1. Neutron detector

    DOEpatents

    Stephan, Andrew C.; Jardret; Vincent D.

    2011-04-05

    A neutron detector has a volume of neutron moderating material and a plurality of individual neutron sensing elements dispersed at selected locations throughout the moderator, and particularly arranged so that some of the detecting elements are closer to the surface of the moderator assembly and others are more deeply embedded. The arrangement captures some thermalized neutrons that might otherwise be scattered away from a single, centrally located detector element. Different geometrical arrangements may be used while preserving its fundamental characteristics. Different types of neutron sensing elements may be used, which may operate on any of a number of physical principles to perform the function of sensing a neutron, either by a capture or a scattering reaction, and converting that reaction to a detectable signal. High detection efficiency, an ability to acquire spectral information, and directional sensitivity may be obtained.

  2. Chemochromic Hydrogen Leak Detectors

    NASA Technical Reports Server (NTRS)

    Roberson, Luke; Captain, Janine; Williams, Martha; Smith, Trent; Tate, LaNetra; Raissi, Ali; Mohajeri, Nahid; Muradov, Nazim; Bokerman, Gary

    2009-01-01

    At NASA, hydrogen safety is a key concern for space shuttle processing. Leaks of any level must be quickly recognized and addressed due to hydrogen s lower explosion limit. Chemo - chromic devices have been developed to detect hydrogen gas in several embodiments. Because hydrogen is odorless and colorless and poses an explosion hazard, there is an emerging need for sensors to quickly and accurately detect low levels of leaking hydrogen in fuel cells and other advanced energy- generating systems in which hydrogen is used as fuel. The device incorporates a chemo - chromic pigment into a base polymer. The article can reversibly or irreversibly change color upon exposure to hydrogen. The irreversible pigment changes color from a light beige to a dark gray. The sensitivity of the pigment can be tailored to its application by altering its exposure to gas through the incorporation of one or more additives or polymer matrix. Furthermore, through the incorporation of insulating additives, the chemochromic sensor can operate at cryogenic temperatures as low as 78 K. A chemochromic detector of this type can be manufactured into any feasible polymer part including injection molded plastic parts, fiber-spun textiles, or extruded tapes. The detectors are simple, inexpensive, portable, and do not require an external power source. The chemochromic detectors were installed and removed easily at the KSC launch pad without need for special expertise. These detectors may require an external monitor such as the human eye, camera, or electronic detector; however, they could be left in place, unmonitored, and examined later for color change to determine whether there had been exposure to hydrogen. In one type of envisioned application, chemochromic detectors would be fabricated as outer layers (e.g., casings or coatings) on high-pressure hydrogen storage tanks and other components of hydrogen-handling systems to provide visible indications of hydrogen leaks caused by fatigue failures or

  3. Neutrino Detectors

    NASA Astrophysics Data System (ADS)

    von Feilitzsch, Franz; Lanfranchi, Jean-Côme; Wurm, Michael

    The neutrino was postulated by Wolfgang Pauli in the early 1930s, but could only be detected for the first time in the 1950s. Ever since scientists all around the world have worked on the detection and understanding of this particle which so scarcely interacts with matter. Depending on the origin and nature of the neutrino, various types of experiments have been developed and operated. In this entry, we will review neutrino detectors in terms of neutrino energy and associated detection technique as well as the scientific outcome of some selected examples. After a brief historical introduction, the detection of low-energy neutrinos originating from nuclear reactors or from the Earth is used to illustrate the principles and difficulties which are encountered in detecting neutrinos. In the context of solar neutrino spectroscopy, where the neutrino is used as a probe for astrophysics, three different types of neutrino detectors are presented - water Čerenkov, radiochemical, and liquid-scintillator detectors. Moving to higher neutrino energies, we discuss neutrinos produced by astrophysical sources and from accelerators. The entry concludes with an overview of a selection of future neutrino experiments and their scientific goals.

  4. The response of smoke detectors to pyrolysis and combustion products from aircraft interior materials

    NASA Technical Reports Server (NTRS)

    Mckee, R. G.; Alvares, N. J.

    1976-01-01

    The following projects were completed as part of the effort to develop and test economically feasible fire-resistant materials for interior furnishings of aircraft as well as detectors of incipient fires in passenger and cargo compartments: (1) determination of the sensitivity of various contemporary gas and smoke detectors to pyrolysis and combustion products from materials commonly used in aircraft interiors and from materials that may be used in the future, (2) assessment of the environmental limitations to detector sensitivity and reliability. The tests were conducted on three groups of materials by exposure to the following three sources of exposure: radiant and Meeker burner flame, heated coil, and radiant source only. The first test series used radiant heat and flame exposures on easily obtainable test materials. Next, four materials were selected from the first group and exposed to an incandescent coil to provide the conditions for smoldering combustion. Finally, radiant heat exposures were used on advanced materials that are not readily available.

  5. In the long run...longitudinal studies of psychopathology in children. Committee on Child Psychology. Group for the Advancement of Psychiatry. Report no.143.

    PubMed

    1999-01-01

    Longitudinal studies are difficult to do well. Too short a study and the results may be meaningless. Too long a study and the subjects cannot be found, money runs out, and research methods become seriously out of date. Despite these problems, there have been some longitudinal studies done that have greatly advanced our understanding of the nature and the treatment of psychopathology in childhood. Without these studies, much less would be known about the clinical course of important disorders, the effects of treatments, and the various risk and protective factors. None of these studies has been perfect. Some longitudinal studies did not focus on quite the right questions, some produced contradictory results, and others produced results that were hard to interpret. What have we learned from the longitudinal studies reviewed in this Group for the Advancement of Psychiatry (GAP) report? Many of the things that we have learned have been surprising--even counterintuitive. Pre- and perinatal insults need not necessarily lead to serious consequences in later life. Premature infants, if raised in nondeprived settings, are not likely to be mentally retarded or learning disabled. Today, of course, premature infants who would not have been kept alive 15 years ago are surviving. Will this advancement led to an untoward outcome? We do not know. New longitudinal studies need to be done. Certain serious illnesses emerging later in childhood may be associated with a greater risk of psychopathology. This risk is true at least for those with asthma. Psychological factors, such as psychological stress, also may lead to exacerbation of asthmatic attacks. Whether other illnesses are associated with a greater risk of psychopathology simply has not been studied adequately. Infant temperamental characteristics can be classified and measured; however, they appear to predict little in terms of later personality development or psychopathology. Although temperamental characteristics measured

  6. Micromechanical uncooled photon detectors

    NASA Astrophysics Data System (ADS)

    Datskos, Panos G.

    2000-04-01

    Recent advances in micro-electro-mechanical systems (MEMS) have led to the development of uncooled IR detectors operate as micromechanical thermal detectors or micromechanical quantum detectors. We report on a new method for photon detection using electronic stresses in semiconductor microstructures. Photo-induced stress in semiconductor microstructures, is caused by changes in the charge carrier density in the conduction band and photon detection results from the measurement of the photon-induced bending of semiconductor microstructures. Small changes in position of microstructures are routinely measured in atomic force microscopy where atomic imaging of surfaces relies on the measurement of small changes in the bending of microcantilevers. Changes in the conduction band charge carrier density can result either from direct photo- generation of free charge carriers or from photoelectrons emitted from thin metal film surface in contact with a semiconductor microstructure which forms a Schottky barrier. In our studies we investigated three systems: (i) Si microstructures, (ii) InSb microstructures and (iii) Si microstructures coated with a thin excess electron-hole- pairs while for InSb photo-induced stress causes the crystal lattice to expand. We will present our results and discuss our findings.

  7. A Monte Carlo simulation comparing hydrocarbons as stopping gases for position sensitive neutron detectors

    NASA Astrophysics Data System (ADS)

    Doumas, A.; Smith, G. C.

    2009-12-01

    Various neutron detectors are being developed for the next generation user facilities, which incorporate new as well as existing approaches for the detection of thermal neutrons. Improvements in neutron detector efficiency, detector size and position resolution have occurred over the last three decades and further advances are expected in the next ten years. Since gas detectors are expected to continue in a key role for future thermal neutron experiments, it is advantageous to review some of the criteria for the choice of proton/triton stopping gases for gas-based detectors. Monte Carlo simulations, using the group of programs "Stopping and Range of Ions in Matter", have been run to determine key performance characteristics for neutron detectors which utilize the reaction 3He(n,p)t. This paper will focus on investigating the use of three common hydrocarbons and CF 4 as stopping gases for thermal neutron detectors. A discussion of these gases will include their behavior in terms of proton and triton range, ion distribution and straggle.

  8. Proceedings of the Second Infrared Detector Technology Workshop

    NASA Technical Reports Server (NTRS)

    Mccreight, C. R. (Compiler)

    1986-01-01

    The workshop focused on infrared detector, detector array, and cryogenic electronic technologies relevant to low-background space astronomy. Papers are organized into the following categories: discrete infrared detectors and readout electronics; advanced bolometers; intrinsic integrated infrared arrays; and extrinsic integrated infrared arrays. Status reports on the Space Infrared Telescope Facility (SIRTF) and Infrared Space Observatory (ISO) programs are also included.

  9. High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia

    PubMed Central

    2013-01-01

    Introduction Staphylococcus (S.) aureus has emerged as an important cause of necrotizing pneumonia. Lung injury during S. aureus pneumonia may be enhanced by local release of damage associated molecular patterns such as high-mobility group box 1 (HMGB1). In the current study we sought to determine the functional role of HMGB1 and its receptors, toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE), in the injurious host response to S. aureus pneumonia. Methods Pneumonia was induced in wild type (Wt), TLR4 deficient (tlr4−/−) and RAGE deficient (rage−/−) mice by intranasal inoculation of 1 × 107 colony-forming units (CFU) of a USA300 S. aureus. In a separate set of experiments, Wt mice were injected intraperitoneally with a monoclonal anti-HMGB1 antibody or an isotype matched control antibody immediately before and every 24 hours after intranasal infection of S. aureus. Mice were sacrificed at 6, 24, 48 or 72 hours after infection for harvesting of blood and organs. Results S. aureus pneumonia was associated with HMGB1 release in the bronchoalveolar compartment peaking after 24 hours. Anti-HMGB1 attenuated lung pathology and protein leak and reduced interleukin-1β release 6 hours after infection, but not at later time points. RAGE deficiency more modestly attenuated lung pathology without influencing protein leak, while TLR4 deficiency did not impact on lung injury. Conclusion These data suggest that HMGB1 and RAGE, but not TLR4, contribute to lung injury accompanying the early phase of S. aureus pneumonia. PMID:24342460

  10. Long-Term Survival Advantage and Prognostic Factors Associated With Intraperitoneal Chemotherapy Treatment in Advanced Ovarian Cancer: A Gynecologic Oncology Group Study

    PubMed Central

    Tewari, Devansu; Java, James J.; Salani, Ritu; Armstrong, Deborah K.; Markman, Maurie; Herzog, Thomas; Monk, Bradley J.; Chan, John K.

    2015-01-01

    Purpose To determine long-term survival and associated prognostic factors after intraperitoneal (IP) chemotherapy in patients with advanced ovarian cancer. Patients and Methods Data from Gynecologic Oncology Group protocols 114 and 172 were retrospectively analyzed. Cox proportional hazards regression models were used for statistical analyses. Results In 876 patients, median follow-up was 10.7 years. Median survival with IP therapy was 61.8 months (95% CI, 55.5 to 69.5), compared with 51.4 months (95% CI, 46.0 to 58.2) for intravenous therapy. IP therapy was associated with a 23% decreased risk of death (adjusted hazard ratio [AHR], 0.77; 95% CI, 0.65 to 0.90; P = .002). IP therapy improved survival of those with gross residual (≤ 1 cm) disease (AHR, 0.75; 95% CI, 0.62 to 0.92; P = .006). Risk of death decreased by 12% for each cycle of IP chemotherapy completed (AHR, 0.88; 95% CI, 0.83 to 0.94; P < .001). Factors associated with poorer survival included: clear/mucinous versus serous histology (AHR, 2.79; 95% CI, 1.83 to 4.24; P < .001), gross residual versus no visible disease (AHR, 1.89; 95% CI, 1.48 to 2.43; P < .001), and fewer versus more cycles of IP chemotherapy (AHR, 0.88; 95% CI, 0.83 to 0.94; P < .001). Younger patients were more likely to complete the IP regimen, with a 5% decrease in probability of completion with each year of age (odds ratio, 0.95; 95% CI, 0.93 to 0.96; P < .001). Conclusion The advantage of IP over intravenous chemotherapy extends beyond 10 years. IP therapy enhanced survival of those with gross residual disease. Survival improved with increasing number of IP cycles. PMID:25800756

  11. Advanced Virgo: AN Update

    NASA Astrophysics Data System (ADS)

    Fafone, Viviana

    2015-01-01

    Significant progress has been made in recent years on the development of gravitational wave detectors. Several km-scale interferometers have already operated at interesting sensitivity levels. In particular, the interferometric detector for gravitational waves Virgo completed its fourth science run in August 2011, when the upgrade toward the second-generation detector Advanced Virgo started. This major upgrade is planned to be completed by 2015. The expected final sensitivity of Advanced Virgo is about ten times better than the sensitivity reached by its predecessor. Many of the components of the detector will be changed to meet this goal, including new core optics, a more powerful laser, an improved vacuum system, the implementation of the signal-recycling technique. In this paper the description of the project and the expected schedule are presented.

  12. Dust Detector

    NASA Technical Reports Server (NTRS)

    Kelley, M. C.

    2001-01-01

    We discuss a recent sounding rocket experiment which found charged dust in the Earth's tropical mesosphere. The dust detector was designed to measure small (5000 - 10000 amu.) charged dust particles, most likely of meteoric origin. A 5 km thick layer of positively charged dust was found at an altitude of 90 km, in the vicinity of an observed sporadic sodium layer and sporadic E layer. The observed dust was positively charged in the bulk of the dust layer, but was negatively charged near the bottom.

  13. Ion detector

    DOEpatents

    Tullis, Andrew M.

    1987-01-01

    An improved ion detector device of the ionization detection device chamber ype comprises an ionization chamber having a central electrode therein surrounded by a cylindrical electrode member within the chamber with a collar frictionally fitted around at least one of the electrodes. The collar has electrical contact means carried in an annular groove in an inner bore of the collar to contact the outer surface of the electrode to provide electrical contact between an external terminal and the electrode without the need to solder leads to the electrode.

  14. Plasmon-resonant microchip emitters and detectors for terahertz sensing and spectroscopic applications

    NASA Astrophysics Data System (ADS)

    Otsuji, Taiichi; Komori, Tsuneyoshi; Watanabe, Takayuki; Suemitsu, Tetsuya; Coquillat, Dominique; Knap, Wojciech

    2010-04-01

    This paper reviews recent advances in emission and detection of terahertz (THz) radiation utilizing two-dimensional plasmons in semiconductor heterostructures and their possible sensing and spectroscopic applications. The device is introduced as a light source into a Fourier-transform THz spectrometer. Water-vapor absorption lines as well as fingerprints of honey and maple syrup of sugar-group materials were successfully observed. Absolute sensitivity characteristics and detection polarization are also presented, showing the possibility of new highly efficient THz detectors.

  15. Advance directives

    PubMed Central

    O’Sullivan, Rory; Mailo, Kevin; Angeles, Ricardo; Agarwal, Gina

    2015-01-01

    Abstract Objective To establish the prevalence of patients with advance directives in a family practice, and to describe patients’ perspectives on a family doctor’s role in initiating discussions about advance directives. Design A self-administered patient questionnaire. Setting A busy urban family medicine teaching clinic in Hamilton, Ont. Participants A convenience sample of adult patients attending the clinic over the course of a typical business week. Main outcome measures The prevalence of advance directives in the patient population was determined, and the patients’ expectations regarding the role of their family doctors were elucidated. Results The survey population consisted of 800 participants (a response rate of 72.5%) well distributed across age groups; 19.7% had written advance directives and 43.8% had previously discussed the topic of advance directives, but only 4.3% of these discussions had occurred with family doctors. In 5.7% of cases, a family physician had raised the issue; 72.3% of respondents believed patients should initiate the discussion. Patients who considered advance directives extremely important were significantly more likely to want their family doctors to start the conversation (odds ratio 3.98; P < .05). Conclusion Advance directives were not routinely addressed in the family practice. Most patients preferred to initiate the discussion of advance directives. However, patients who considered the subject extremely important wanted their family doctors to initiate the discussion. PMID:25873704

  16. High speed, high performance /Hg,Cd/Te photodiode detectors.

    NASA Technical Reports Server (NTRS)

    Soderman, D. A.; Pinkston, W. H.

    1972-01-01

    The current performance of high speed photodiode detectors for the 1 to 10 micron spectral region is discussed. The (Hg,Cd)Te photodiode configuration, detector properties, integration in laser receiver modules, and frequency response are considered for near infrared and far infrared wavelengths. The recent advances in (Hg,Cd)Te material and device development are indicated by the realization not only of exceptionally high speed detectors but of detectors that exhibit excellent detectivities. The performance improves substantially when the detector is cooled. This detector junction technology has been extended to other compositions of (Hg,Cd)Te for peak spectral responses at 5 and 10 micron.

  17. High-mobility group box 1 inhibits HCO(3)(-) absorption in medullary thick ascending limb through a basolateral receptor for advanced glycation end products pathway.

    PubMed

    Good, David W; George, Thampi; Watts, Bruns A

    2015-10-15

    High-mobility group box 1 (HMGB1) is a damage-associated molecule implicated in mediating kidney dysfunction in sepsis and sterile inflammatory disorders. HMGB1 is a nuclear protein released extracellularly in response to infection or injury, where it interacts with Toll-like receptor 4 (TLR4) and other receptors to mediate inflammation. Previously, we demonstrated that LPS inhibits HCO(3)(-) absorption in the medullary thick ascending limb (MTAL) through a basolateral TLR4-ERK pathway (Watts BA III, George T, Sherwood ER, Good DW. Am J Physiol Cell Physiol 301: C1296-C1306, 2011). Here, we examined whether HMGB1 could inhibit HCO(3)(-) absorption through the same pathway. Adding HMGB1 to the bath decreased HCO(3)(-) absorption by 24% in isolated, perfused rat and mouse MTALs. In contrast to LPS, inhibition by HMGB1 was preserved in MTALs from TLR4(-/-) mice and was unaffected by ERK inhibitors. Inhibition by HMGB1 was eliminated by the receptor for advanced glycation end products (RAGE) antagonist FPS-ZM1 and by neutralizing anti-RAGE antibody. Confocal immunofluorescence showed expression of RAGE in the basolateral membrane domain. Inhibition of HCO(3)(-) absorption by HMGB1 through RAGE was additive to inhibition by LPS through TLR4 and to inhibition by Gram-positive bacterial molecules through TLR2. Bath amiloride, which selectively prevents inhibition of MTAL HCO(3)(-) absorption mediated through Na⁺/H⁺ exchanger 1 (NHE1), eliminated inhibition by HMGB1. We conclude that HMGB1 inhibits MTAL HCO(3)(-) absorption through a RAGE-dependent pathway distinct from TLR4-mediated inhibition by LPS. These studies provide new evidence that HMGB1-RAGE signaling acts directly to impair the transport function of renal tubules. They reveal a novel paradigm for sepsis-induced renal tubule dysfunction, whereby exogenous pathogen-associated molecules and endogenous damage-associated molecules act directly and independently to inhibit MTAL HCO(3)(-) absorption through

  18. Workshop on detectors for third-generation synchrotron sources: Proceedings

    SciTech Connect

    1994-12-01

    The aims of the workshop were (1) to acquaint APS users with current R and D being carried out on detectors, (2) to identify new detector systems possible during the next five years, (3) to identify new detectors theoretically possible in the future, (4) to stimulate interactions between user groups and detector developers, and (5) to obtain recommendations from expert panels on technical issues needing resolution. Development of detectors at ESRF, Spring-8, BNL, CERN and LBL are included.

  19. Oscillator detector

    SciTech Connect

    Potter, B.M.

    1980-05-13

    An alien liquid detector employs a monitoring element and an oscillatory electronic circuit for maintaining the temperature of the monitoring element substantially above ambient temperature. The output wave form, eg., frequency of oscillation or wave shape, of the oscillatory circuit depends upon the temperaturedependent electrical characteristic of the monitoring element. A predetermined change in the output waveform allows water to be discriminated from another liquid, eg., oil. Features of the invention employing two thermistors in two oscillatory circuits include positioning one thermistor for contact with water and the other thermistor above the oil-water interface to detect a layer of oil if present. Unique oscillatory circuit arrangements are shown that achieve effective thermistor action with an economy of parts and energizing power. These include an operational amplifier employed in an astable multivibrator circuit, a discrete transistor-powered tank circuit, and use of an integrated circuit chip.

  20. Ice detector

    NASA Technical Reports Server (NTRS)

    Weinstein, Leonard M. (Inventor)

    1988-01-01

    An ice detector is provided for the determination of the thickness of ice on the outer surface on an object (e.g., aircraft) independently of temperature or the composition of the ice. First capacitive gauge, second capacitive gauge, and temperature gauge are embedded in embedding material located within a hollowed out portion of the outer surface. This embedding material is flush with the outer surface to prevent undesirable drag. The first capacitive gauge, second capacitive gauge, and the temperature gauge are respectively connected to first capacitive measuring circuit, second capacitive measuring circuit, and temperature measuring circuit. The geometry of the first and second capacitive gauges is such that the ratio of the voltage outputs of the first and second capacitance measuring circuits is proportional to the thickness of ice, regardless of ice temperature or composition. This ratio is determined by offset and dividing circuit.

  1. Advanced Fire Detector for Space Applications

    NASA Technical Reports Server (NTRS)

    Kutzner, Joerg

    2012-01-01

    A document discusses an optical carbon monoxide sensor for early fire detection. During the sensor development, a concept was implemented to allow reliable carbon monoxide detection in the presence of interfering absorption signals. Methane interference is present in the operating wavelength range of the developed prototype sensor for carbon monoxide detection. The operating parameters of the prototype sensor have been optimized so that interference with methane is minimized. In addition, simultaneous measurement of methane is implemented, and the instrument automatically corrects the carbon monoxide signal at high methane concentrations. This is possible because VCSELs (vertical cavity surface emitting lasers) with extended current tuning capabilities are implemented in the optical device. The tuning capabilities of these new laser sources are sufficient to cover the wavelength range of several absorption lines. The delivered carbon monoxide sensor (COMA 1) reliably measures low carbon monoxide levels even in the presence of high methane signals. The signal bleed-over is determined during system calibration and is then accounted for in the system parameters. The sensor reports carbon monoxide concentrations reliably for (interfering) methane concentrations up to several thousand parts per million.

  2. Far-Infrared Blocked Impurity Band Detector Development

    NASA Technical Reports Server (NTRS)

    Hogue, H. H.; Guptill, M. T.; Monson, J. C.; Stewart, J. W.; Huffman, J. E.; Mlynczak, M. G.; Abedin, M. N.

    2007-01-01

    DRS Sensors & Targeting Systems, supported by detector materials supplier Lawrence Semiconductor Research Laboratory, is developing far-infrared detectors jointly with NASA Langley under the Far-IR Detector Technology Advancement Partnership (FIDTAP). The detectors are intended for spectral characterization of the Earth's energy budget from space. During the first year of this effort we have designed, fabricated, and evaluated pilot Blocked Impurity Band (BIB) detectors in both silicon and germanium, utilizing pre-existing customized detector materials and photolithographic masks. A second-year effort has prepared improved silicon materials, fabricated custom photolithographic masks for detector process, and begun detector processing. We report the characterization results from the pilot detectors and other progress.

  3. Chemical warfare detectors worldwide

    SciTech Connect

    Corriveau, J.

    1995-06-01

    The purpose of this presentation is to provide information on the principal technologies used to detect and identify chemical warfare (CW) agents. Detectors of harmful CW agents may be grouped into three major categories based on their operating principles. The three technologies involved are biochemical, ion mobility spectrometry (IMS), and flame photometry (FP). Once a chemical agent has been detected by one of these means, the presence must often be {open_quotes}confirmed{close_quotes} by a second test that is based on a different technology. Two major means of confirming the presence of a chemical agent are mass spectrometry (MS) and {open_quotes}classical{close_quotes} wet chemistry.

  4. Micro UV detector

    NASA Astrophysics Data System (ADS)

    Cabalo, Jerry B.; Sickenberger, Richard; Underwood, William J.; Sickenberger, David W.

    2004-09-01

    A lightweight, tactical biological agent detection network offers the potential for a detect-to-warn capability against biological aerosol attacks. Ideally, this capability can be achieved by deploying the sensors upwind from the protected assets. The further the distance upwind, the greater the warning time. The technological challenge to this concept is the biological detection technology. Here, cost, size and power are major factors in selecting acceptable technologies. This is in part due to the increased field densities needed to cover the upwind area and the fact that the sensors, when deployed forward, must operate autonomously for long periods of time with little or no long-term logistical support. The Defense Advanced Research Project Agency"s (DARPA) Solid-state Ultraviolet Optical Source (SUVOS) program offers an enabling technology to achieving a detector compatible with this mission. As an optical source, these devices emit excitation wavelengths known to be useful in the detection of biological aerosols. The wavelength band is absorbed by the biological aerosol and results in visible fluorescence. Detection of a biological aerosol is based on the observed intensity of this fluorescence signal compared to a background reference. Historically this has been accomplished with emission sources that are outside the boundaries for low cost, low power sensors. The SUVOS technology, on the other hand, provides the same basic wavelengths needed for the detection process in a small, low power package. ECBC has initiated an effort to develop a network array based on micro UV detectors that utilize the SUVOS technology. This paper presents an overview of the micro UV detector and some of the findings to date. This includes the overall design philosophy, fluid flow calculations to maximize presentation of aerosol particles to the sources, and the fluorescence measurements.

  5. Micro-UV detector

    NASA Astrophysics Data System (ADS)

    Cabalo, Jerry B.; Sickenberger, Richard; Underwood, William J.; Sickenberger, David W.

    2004-12-01

    A lightweight, tactical biological agent detection network offers the potential for a detect-to-warn capability against biological aerosol attacks. Ideally, this capability can be achieved by deploying the sensors upwind from the protected assets. The further the distance upwind, the greater the warning time. The technological challenge to this concept is the biological detection technology. Here, cost, size and power are major factors in selecting acceptable technologies. This is in part due to the increased field densities needed to cover the upwind area and the fact that the sensors, when deployed forward, must operate autonomously for long periods of time with little or no long-term logistical support. The Defense Advanced Research Project Agency"s (DARPA) Solid-state Ultraviolet Optical Source (SUVOS) program offers an enabling technology to achieving a detector compatible with this mission. As an optical source, these devices emit excitation wavelengths known to be useful in the detection of biological aerosols. The wavelength band is absorbed by the biological aerosol and results in visible fluorescence. Detection of a biological aerosol is based on the observed intensity of this fluorescence signal compared to a background reference. Historically this has been accomplished with emission sources that are outside the boundaries for low cost, low power sensors. The SUVOS technology, on the other hand, provides the same basic wavelengths needed for the detection process in a small, low power package. ECBC has initiated an effort to develop a network array based on micro UV detectors that utilize the SUVOS technology. This paper presents an overview of the micro UV detector and some of the findings to date. This includes the overall design philosophy, fluid flow calculations to maximize presentation of aerosol particles to the sources, and the fluorescence measurements.

  6. Are Advanced Placement English and First-Year College Composition Equivalent? A Comparison of Outcomes in the Writing of Three Groups of Sophomore College Students

    ERIC Educational Resources Information Center

    Hansen, Kristine; Reeve, Suzanne; Gonzalez, Jennifer; Sudweeks, Richard R.; Hatch, Gary L.; Esplin, Patricia; Bradshaw, William S.

    2006-01-01

    This study was conducted to obtain empirical data to inform policy decisions about exempting incoming students from a first-year composition (FYC) course on the basis of Advanced Placement (AP) English exam scores. It examined the effect of avoiding first-year writing on the writing abilities of sophomore undergraduates. Two three-page writing…

  7. Future of Semiconductor Based Thermal Neutron Detectors

    SciTech Connect

    Nikolic, R J; Cheung, C L; Reinhardt, C E; Wang, T F

    2006-02-22

    Thermal neutron detectors have seen only incremental improvements over the last decades. In this paper we overview the current technology of choice for thermal neutron detection--{sup 3}He tubes, which suffer from, moderate to poor fieldability, and low absolute efficiency. The need for improved neutron detection is evident due to this technology gap and the fact that neutrons are a highly specific indicator of fissile material. Recognizing this need, we propose to exploit recent advances in microfabrication technology for building the next generation of semiconductor thermal neutron detectors for national security requirements, for applications requiring excellent fieldability of small devices. We have developed an innovative pathway taking advantage of advanced processing and fabrication technology to produce the proposed device. The crucial advantage of our Pillar Detector is that it can simultaneously meet the requirements of high efficiency and fieldability in the optimized configuration, the detector efficiency could be higher than 70%.

  8. Performance of an AGATA asymmetric detector

    SciTech Connect

    Boston, A. J.; Dimmock, M. R.; Unsworth, C.; Boston, H. C.; Cooper, R. J.; Grint, A. N.; Harkness, L. J.; Jones, M.; Nolan, P. J.; Oxley, D. C.; Slee, M.; Lazarus, I. H.; Simpson, J.

    2008-11-11

    Each major technical advance in gamma-ray detection devices has resulted in significant new insights into the structure of atomic nuclei. The next major step in gamma-ray spectroscopy involves achieving the goal of a 4{pi} ball of germanium detectors by using the technique of gamma-ray energy tracking in electrically segmented germanium crystals. The resulting spectrometer will have an unparalleled level of detection power for nuclear electromagnetic radiation. Collaborations have been established in Europe (AGATA)[1] and the USA (GRETA/GRETINA)[2] to build gamma-ray tracking spectrometers. This paper discusses the performance of the first AGATA (Advanced GAmma Tracking Array) asymmetric detector that has been tested at the University of Liverpool. The use of a fully digital data acquisition system has allowed detector charge pulse shapes from a selection of well defined photon interaction positions to be analysed, yielding important information on the position sensitivity of the detector.

  9. Pixel detectors for diffraction-limited storage rings

    PubMed Central

    Denes, Peter; Schmitt, Bernd

    2014-01-01

    Dramatic advances in synchrotron radiation sources produce ever-brighter beams of X-rays, but those advances can only be used if there is a corresponding improvement in X-ray detectors. With the advent of storage ring sources capable of being diffraction-limited (down to a certain wavelength), advances in detector speed, dynamic range and functionality is required. While many of these improvements in detector capabilities are being pursued now, the orders-of-magnitude increases in brightness of diffraction-limited storage ring sources will require challenging non-incremental advances in detectors. This article summarizes the current state of the art, developments underway worldwide, and challenges that diffraction-limited storage ring sources present for detectors. PMID:25177989

  10. Detector simulation needs for detector designers

    SciTech Connect

    Hanson, G.G.

    1987-11-01

    Computer simulation of the components of SSC detectors and of the complete detectors will be very important for the designs of the detectors. The ratio of events from interesting physics to events from background processes is very low, so detailed understanding of detector response to the backgrounds is needed. Any large detector for the SSC will be very complex and expensive and every effort must be made to design detectors which will have excellent performance and will not have to undergo major rebuilding. Some areas in which computer simulation is particularly needed are pattern recognition in tracking detectors and development of shower simulation code which can be trusted as an aid in the design and optimization of calorimeters, including their electron identification performance. Existing codes require too much computer time to be practical and need to be compared with test beam data at energies of several hundred GeV. Computer simulation of the processing of the data, including electronics response to the signals from the detector components, processing of the data by microprocessors on the detector, the trigger, and data acquisition will be required. In this report we discuss the detector simulation needs for detector designers.

  11. Causal particle detectors and topology

    SciTech Connect

    Langlois, Paul . E-mail: pmxppl@nottingham.ac.uk

    2006-09-15

    We investigate particle detector responses in some topologically non-trivial spacetimes. We extend a recently proposed regularization of the massless scalar field Wightman function in four-dimensional Minkowski space to arbitrary dimension, to the massive scalar field, to quotients of Minkowski space under discrete isometry groups and to the massless Dirac field. We investigate in detail the transition rate of inertial and uniformly accelerated detectors on the quotient spaces under groups generated by (t,x,y,z)-bar (t,x,y,z+2a), (t,x,y,z)-bar (t,-x,y,z), (t,x,y,z)-bar (t,-x,-y,z), (t,x,y,z)-bar (t,-x,-y,z+a) and some higher dimensional generalizations. For motions in at constant y and z on the latter three spaces the response is time dependent. We also discuss the response of static detectors on the RP{sup 3} geon and inertial detectors on RP{sup 3} de Sitter space via their associated global embedding Minkowski spaces (GEMS). The response on RP{sup 3} de Sitter space, found both directly and in its GEMS, provides support for the validity of applying the GEMS procedure to detector responses and to quotient spaces such as RP{sup 3} de Sitter space and the RP{sup 3} geon where the embedding spaces are Minkowski spaces with suitable identifications.

  12. Enhanced neutron imaging detector using optical processing

    SciTech Connect

    Hutchinson, D.P.; McElhaney, S.A.

    1992-08-01

    Existing neutron imaging detectors have limited count rates due to inherent property and electronic limitations. The popular multiwire proportional counter is qualified by gas recombination to a count rate of less than 10{sup 5} n/s over the entire array and the neutron Anger camera, even though improved with new fiber optic encoding methods, can only achieve 10{sup 6} cps over a limited array. We present a preliminary design for a new type of neutron imaging detector with a resolution of 2--5 mm and a count rate capability of 10{sup 6} cps pixel element. We propose to combine optical and electronic processing to economically increase the throughput of advanced detector systems while simplifying computing requirements. By placing a scintillator screen ahead of an optical image processor followed by a detector array, a high throughput imaging detector may be constructed.

  13. Additional mutations in SRSF2, ASXL1 and/or RUNX1 identify a high-risk group of patients with KIT D816V(+) advanced systemic mastocytosis.

    PubMed

    Jawhar, M; Schwaab, J; Schnittger, S; Meggendorfer, M; Pfirrmann, M; Sotlar, K; Horny, H-P; Metzgeroth, G; Kluger, S; Naumann, N; Haferlach, C; Haferlach, T; Valent, P; Hofmann, W-K; Fabarius, A; Cross, N C P; Reiter, A

    2016-01-01

    Most patients with KIT D816V(+) advanced systemic mastocytosis (SM) are characterized by somatic mutations in additional genes. We sought to clarify the prognostic impact of such mutations. Genotype and clinical characteristics of 70 multi-mutated KIT D816V(+) advanced SM patients were included in univariate and multivariate analyses. The most frequently identified mutated genes were TET2 (n=33 of 70 patients), SRSF2 (n=30), ASXL1 (n=20), RUNX1 (n=16) and JAK2 (n=11). In univariate analysis, overall survival (OS) was adversely influenced by mutations in SRSF2 (P<0.0001), ASXL1 (P=0.002) and RUNX1 (P=0.03), but was not influenced by mutations in TET2 or JAK2. In multivariate analysis, SRSF2 and ASXL1 remained the most predictive adverse indicators concerning OS. Furthermore, we found that inferior OS and adverse clinical characteristics were significantly influenced by the number of mutated genes in the SRSF2/ASXL1/RUNX1 (S/A/R) panel (P<0.0001). In conclusion, the presence and number of mutated genes within the S/A/R panel are adversely associated with advanced disease and poor survival in KIT D816V(+) SM. On the basis of these findings, inclusion of molecular markers should be considered in upcoming prognostic scoring systems for patients with SM. PMID:26464169

  14. Independent detector testing laboratory and the NGST detector characterization project

    NASA Astrophysics Data System (ADS)

    Figer, Donald F.; Rauscher, Bernard J.; Regan, Michael W.; Balleza, Jesus C.; Barkhouser, Robert H.; Bergeron, Louis E.; Greene, Gretchen R.; Kim, Sungsoo; McCandliss, Stephan R.; Morse, Ernie; Pelton, Russell; Reeves, Thomas; Sharma, Utkarsh; Stemniski, P.; Stockman, Hervey S.; Telewicz, M.

    2003-03-01

    The Independent Detector Testing Laboratory (IDTL) has been established by the Space Telescope Science Institute (STScI) and the Johns Hopkins University (JHU), and it will assist the Next Generation Space Telescope (NGST) mission in choosing and operating the best near-infrared detectors. The NGST is the centerpiece of the NASA Office of Space Science theme, the Astronomical Search for Origins, and the highest priority astronomy project for the next decade, according to the National Academy of Science. NGST will need to have the sensitivity to see the first light in the Universe to determine how galaxies formed in the web of dark matter that existed when the Universe was in its infancy (z ~10-20). To achieve this goal, the NGST Project must pursue an aggressive technology program and advance infrared detectors to performance levels beyond what is now possible. As part of this program, NASA has selected the IDTL to verify comparative performance between prototype NGST detectors developed by Rockwell Scientific (HgCdTe) and Raytheon (InSb). The IDTL is charged with obtaining an independent assessment of the ability of these two competing technologies to achieve the demanding specifications of the NGST program within the 0.6-5 μm bandpass and in an ultra-low background (<0.01 e-/s/pixel) environment. We describe the NGST Detector Characterization Project that is being performed in the IDTL. In this project, we will measure first-order detector parameters, i.e. dark current, read noise, QE, intra-pixel sensitivity, linearity, as functions of temperature, well size, and operational mode.

  15. The Independent Detector Testing Laboratory and the JWST Detector Program

    NASA Astrophysics Data System (ADS)

    Figer, D. F.; Rauscher, B. J.; Regan, M. W.; Balleza, J.; Barkhouser, R.; Bergeron, L.; Greene, G. R.; McCandliss, S. R.; Morse, E.; Reeves, T.; Stockman, H. S.

    2002-12-01

    The Independent Detector Testing Laboratory (IDTL) is jointly operated by the Space Telescope Science Institute (STScI) and the Johns Hopkins University (JHU), and is assisting the James Webb Space Telescope (JWST) mission in choosing and operating the best near-infrared detectors. The JWST is the centerpiece of the NASA Office of Space Science theme, the Astronomical Search for Origins, and the highest priority astronomy project for the next decade, according to the National Academy of Science. JWST will need to have the sensitivity to see the first light in the Universe to determine how galaxies formed in the web of dark matter that existed when the Universe was in its infancy (z ~10-20). To achieve this goal, the JWST Project must pursue an aggressive technology program and advance infrared detectors to performance levels beyond what is now possible. As part of this program, NASA has selected the IDTL to verify comparative performance between prototype JWST detectors developed by Rockwell Scientific (HgCdTe) and Raytheon (InSb). The IDTL is charged with obtaining an independent assessment of the ability of these two competing technologies to achieve the demanding specifications of the JWST program within the 0.6-5 μ m bandpass and in an ultra-low background (<0.01 e-/s/pixel) environment. We describe the JWST Detector Characterization Project that is being performed in the IDTL. In this project, we will measure first-order detector parameters, i.e. dark current, read noise, QE, intra-pixel sensitivity, linearity, as functions of temperature, well size, and operational mode.

  16. Improving the data quality of Advanced LIGO based on early engineering run results

    NASA Astrophysics Data System (ADS)

    Nuttall, L. K.; Massinger, T. J.; Areeda, J.; Betzwieser, J.; Dwyer, S.; Effler, A.; Fisher, R. P.; Fritschel, P.; Kissel, J. S.; Lundgren, A. P.; Macleod, D. M.; Martynov, D.; McIver, J.; Mullavey, A.; Sigg, D.; Smith, J. R.; Vajente, G.; Williamson, A. R.; Wipf, C. C.

    2015-12-01

    The Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors have completed their initial upgrade phase and will enter the first observing run in late 2015, with detector sensitivity expected to improve in future runs. Through the combined efforts of on-site commissioners and the Detector Characterization Group of the LIGO Scientific Collaboration, interferometer performance, in terms of data quality, at both LIGO observatories has vastly improved from the start of commissioning efforts to present. Advanced LIGO has already surpassed Enhanced LIGO in sensitivity, and the rate of noise transients, which would negatively impact astrophysical searches, has improved. Here we give details of some of the work which has taken place to better the quality of the LIGO data ahead of the first observing run.

  17. Continued development of room temperature semiconductor nuclear detectors

    NASA Astrophysics Data System (ADS)

    Kim, Hadong; Cirignano, Leonard; Churilov, Alexei; Ciampi, Guido; Kargar, Alireza; Higgins, William; O'Dougherty, Patrick; Kim, Suyoung; Squillante, Michael R.; Shah, Kanai

    2010-08-01

    Thallium bromide (TlBr) and related ternary compounds, TlBrI and TlBrCl, have been under development for room temperature gamma ray spectroscopy due to several promising properties. Due to recent advances in material processing, electron mobility-lifetime product of TlBr is close to Cd(Zn)Te's value which allowed us to fabricate large working detectors. We were also able to fabricate and obtain spectroscopic results from TlBr Capacitive Frisch Grid detector and orthogonal strip detectors. In this paper we report on our recent TlBr and related ternary detector results and preliminary results from Cinnabar (HgS) detectors.

  18. Allogeneic stem cell transplantation for advanced cutaneous T-cell lymphomas: a study from the French Society of Bone Marrow Transplantation and French Study Group on Cutaneous Lymphomas.

    PubMed

    de Masson, Adèle; Beylot-Barry, Marie; Bouaziz, Jean-David; Peffault de Latour, Régis; Aubin, François; Garciaz, Sylvain; d'Incan, Michel; Dereure, Olivier; Dalle, Stéphane; Dompmartin, Anne; Suarez, Felipe; Battistella, Maxime; Vignon-Pennamen, Marie-Dominique; Rivet, Jacqueline; Adamski, Henri; Brice, Pauline; François, Sylvie; Lissandre, Séverine; Turlure, Pascal; Wierzbicka-Hainaut, Ewa; Brissot, Eolia; Dulery, Rémy; Servais, Sophie; Ravinet, Aurélie; Tabrizi, Reza; Ingen-Housz-Oro, Saskia; Joly, Pascal; Socié, Gérard; Bagot, Martine

    2014-03-01

    The treatment of advanced stage primary cutaneous T-cell lymphomas remains challenging. In particular, large-cell transformation of mycosis fungoides is associated with a median overall survival of two years for all stages taken together. Little is known regarding allogeneic hematopoietic stem cell transplantation in this context. We performed a multicenter retrospective analysis of 37 cases of advanced stage primary cutaneous T-cell lymphomas treated with allogeneic stem cell transplantation, including 20 (54%) transformed mycosis fungoides. Twenty-four patients (65%) had stage IV disease (for mycosis fungoides and Sézary syndrome) or disseminated nodal or visceral involvement (for non-epidermotropic primary cutaneous T-cell lymphomas). After a median follow up of 29 months, 19 patients experienced a relapse, leading to a 2-year cumulative incidence of relapse of 56% (95%CI: 0.38-0.74). Estimated 2-year overall survival was 57% (95%CI: 0.41-0.77) and progression-free survival 31% (95%CI: 0.19-0.53). Six of 19 patients with a post-transplant relapse achieved a subsequent complete remission after salvage therapy, with a median duration of 41 months. A weak residual tumor burden before transplantation was associated with increased progression-free survival (HR=0.3, 95%CI: 0.1-0.8; P=0.01). The use of antithymocyte globulin significantly reduced progression-free survival (HR=2.9, 95%CI: 1.3-6.2; P=0.01) but also transplant-related mortality (HR=10(-7), 95%CI: 4.10(-8)-2.10(-7); P<0.001) in univariate analysis. In multivariate analysis, the use of antithymocyte globulin was the only factor significantly associated with decreased progression-free survival (P=0.04). Allogeneic stem cell transplantation should be considered in advanced stage primary cutaneous T-cell lymphomas, including transformed mycosis fungoides. PMID:24213148

  19. Advanced LIGO

    NASA Astrophysics Data System (ADS)

    LIGO Scientific Collaboration; Aasi, J.; Abbott, B. P.; Abbott, R.; Abbott, T.; Abernathy, M. R.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V.; Affeldt, C.; Aggarwal, N.; Aguiar, O. D.; Ain, A.; Ajith, P.; Alemic, A.; Allen, B.; Amariutei, D.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C.; Areeda, J. S.; Ashton, G.; Ast, S.; Aston, S. M.; Aufmuth, P.; Aulbert, C.; Aylott, B. E.; Babak, S.; Baker, P. T.; Ballmer, S. W.; Barayoga, J. C.; Barbet, M.; Barclay, S.; Barish, B. C.; Barker, D.; Barr, B.; Barsotti, L.; Bartlett, J.; Barton, M. A.; Bartos, I.; Bassiri, R.; Batch, J. C.; Baune, C.; Behnke, B.; Bell, A. S.; Bell, C.; Benacquista, M.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Biscans, S.; Biwer, C.; Blackburn, J. K.; Blackburn, L.; Blair, C. D.; Blair, D.; Bock, O.; Bodiya, T. P.; Bojtos, P.; Bond, C.; Bork, R.; Born, M.; Bose, Sukanta; Brady, P. R.; Braginsky, V. B.; Brau, J. E.; Bridges, D. O.; Brinkmann, M.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchman, S.; Buikema, A.; Buonanno, A.; Cadonati, L.; Calderón Bustillo, J.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Caride, S.; Caudill, S.; Cavaglià, M.; Cepeda, C.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chao, S.; Charlton, P.; Chen, Y.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Collette, C.; Cominsky, L.; Constancio, M., Jr.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Costa, C. A.; Coughlin, M. W.; Countryman, S.; Couvares, P.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Creighton, T. D.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cutler, C.; Dahl, K.; Dal Canton, T.; Damjanic, M.; Danilishin, S. L.; Danzmann, K.; Dartez, L.; Dave, I.; Daveloza, H.; Davies, G. S.; Daw, E. J.; DeBra, D.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; D´ıaz, M.; Di Palma, I.; Dojcinoski, G.; Dominguez, E.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Driggers, J. C.; Du, Z.; Dwyer, S.; Eberle, T.; Edo, T.; Edwards, M.; Edwards, M.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Essick, R.; Etzel, T.; Evans, M.; Evans, T.; Factourovich, M.; Fairhurst, S.; Fan, X.; Fang, Q.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Feldbaum, D.; Ferreira, E. C.; Fisher, R. P.; Frei, Z.; Freise, A.; Frey, R.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fuentes-Tapia, S.; Fulda, P.; Fyffe, M.; Gair, J. R.; Gaonkar, S.; Gehrels, N.; Gergely, L. Á.; Giaime, J. A.; Giardina, K. D.; Gleason, J.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gordon, N.; Gorodetsky, M. L.; Gossan, S.; Goßler, S.; Gräf, C.; Graff, P. B.; Grant, A.; Gras, S.; Gray, C.; Greenhalgh, R. J. S.; Gretarsson, A. M.; Grote, H.; Grunewald, S.; Guido, C. J.; Guo, X.; Gushwa, K.; Gustafson, E. K.; Gustafson, R.; Hacker, J.; Hall, E. D.; Hammond, G.; Hanke, M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harry, G. M.; Harry, I. W.; Hart, M.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Hee, S.; Heintze, M.; Heinzel, G.; Hendry, M.; Heng, I. S.; Heptonstall, A. W.; Heurs, M.; Hewitson, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hollitt, S. E.; Holt, K.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E.; Howell, E. J.; Hu, Y. M.; Huerta, E.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh, M.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Islas, G.; Isler, J. C.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacobson, M.; Jang, H.; Jawahar, S.; Ji, Y.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Ju, L.; Haris, K.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Katsavounidis, E.; Katzman, W.; Kaufer, H.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Keiser, G. M.; Keitel, D.; Kelley, D. B.; Kells, W.; Keppel, D. G.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khazanov, E. A.; Kim, C.; Kim, K.; Kim, N. G.; Kim, N.; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Klimenko, S.; Kline, J.; Koehlenbeck, S.; Kokeyama, K.; Kondrashov, V.; Korobko, M.; Korth, W. Z.; Kozak, D. B.; Kringel, V.; Krishnan, B.; Krueger, C.; Kuehn, G.; Kumar, A.; Kumar, P.; Kuo, L.; Landry, M.; Lantz, B.; Larson, S.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Le, J.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Leong, J. R.; Levin, Y.; Levine, B.; Lewis, J.; Li, T. G. F.; Libbrecht, K.; Libson, A.; Lin, A. C.; Littenberg, T. B.; Lockerbie, N. A.; Lockett, V.; Logue, J.; Lombardi, A. L.; Lormand, M.; Lough, J.; Lubinski, M. J.; Lück, H.; Lundgren, A. P.; Lynch, R.; Ma, Y.; Macarthur, J.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R.; Mageswaran, M.; Maglione, C.; Mailand, K.; Mandel, I.; Mandic, V.; Mangano, V.; Mansell, G. L.; Márka, S.; Márka, Z.; Markosyan, A.; Maros, E.; Martin, I. W.; Martin, R. M.; Martynov, D.; Marx, J. N.; Mason, K.; Massinger, T. J.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McLin, K.; McWilliams, S.; Meadors, G. D.; Meinders, M.; Melatos, A.; Mendell, G.; Mercer, R. A.; Meshkov, S.; Messenger, C.; Meyers, P. M.; Miao, H.; Middleton, H.; Mikhailov, E. E.; Miller, A.; Miller, J.; Millhouse, M.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moe, B.; Mohanty, S. D.; Mohapatra, S. R. P.; Moore, B.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Mukherjee, S.; Mullavey, A.; Munch, J.; Murphy, D.; Murray, P. G.; Mytidis, A.; Nash, T.; Nayak, R. K.; Necula, V.; Nedkova, K.; Newton, G.; Nguyen, T.; Nielsen, A. B.; Nissanke, S.; Nitz, A. H.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oppermann, P.; Oram, R.; O'Reilly, B.; Ortega, W.; O'Shaughnessy, R.; Osthelder, C.; Ott, C. D.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Padilla, C.; Pai, A.; Pai, S.; Palashov, O.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Papa, M. A.; Paris, H.; Patrick, Z.; Pedraza, M.; Pekowsky, L.; Pele, A.; Penn, S.; Perreca, A.; Phelps, M.; Pierro, V.; Pinto, I. M.; Pitkin, M.; Poeld, J.; Post, A.; Poteomkin, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S.; Prestegard, T.; Price, L. R.; Principe, M.; Privitera, S.; Prix, R.; Prokhorov, L.; Puncken, O.; Pürrer, M.; Qin, J.; Quetschke, V.; Quintero, E.; Quiroga, G.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rajalakshmi, G.; Rakhmanov, M.; Ramirez, K.; Raymond, V.; Reed, C. M.; Reid, S.; Reitze, D. H.; Reula, O.; Riles, K.; Robertson, N. A.; Robie, R.; Rollins, J. G.; Roma, V.; Romano, J. D.; Romanov, G.; Romie, J. H.; Rowan, S.; Rüdiger, A.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Saleem, M.; Salemi, F.; Sammut, L.; Sandberg, V.; Sanders, J. R.; Sannibale, V.; Santiago-Prieto, I.; Sathyaprakash, B. S.; Saulson, P. R.; Savage, R.; Sawadsky, A.; Scheuer, J.; Schilling, R.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sergeev, A.; Serna, G.; Sevigny, A.; Shaddock, D. A.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Shoemaker, D. H.; Sidery, T. L.; Siemens, X.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L.; Singh, R.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, M. R.; Smith, R. J. E.; Smith-Lefebvre, N. D.; Son, E. J.; Sorazu, B.; Souradeep, T.; Staley, A.; Stebbins, J.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Steplewski, S.; Stevenson, S.; Stone, R.; Strain, K. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sutton, P. J.; Szczepanczyk, M.; Szeifert, G.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Tellez, G.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, V.; Tomlinson, C.; Torres, C. V.; Torrie, C. I.; Traylor, G.; Tse, M.; Tshilumba, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; Vallisneri, M.; van Veggel, A. A.; Vass, S.; Vaulin, R.; Vecchio, A.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Vincent-Finley, R.; Vitale, S.; Vo, T.; Vorvick, C.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, H.; Wang, M.; Wang, X.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Wessels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D. J.; Whiting, B. F.; Wilkinson, C.; Williams, L.; Williams, R.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Xie, S.; Yablon, J.; Yakushin, I.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yang, Q.; Zanolin, M.; Zhang, Fan; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhu, X. J.; Zucker, M. E.; Zuraw, S.; Zweizig, J.

    2015-04-01

    The Advanced LIGO gravitational wave detectors are second-generation instruments designed and built for the two LIGO observatories in Hanford, WA and Livingston, LA, USA. The two instruments are identical in design, and are specialized versions of a Michelson interferometer with 4 km long arms. As in Initial LIGO, Fabry-Perot cavities are used in the arms to increase the interaction time with a gravitational wave, and power recycling is used to increase the effective laser power. Signal recycling has been added in Advanced LIGO to improve the frequency response. In the most sensitive frequency region around 100 Hz, the design strain sensitivity is a factor of 10 better than Initial LIGO. In addition, the low frequency end of the sensitivity band is moved from 40 Hz down to 10 Hz. All interferometer components have been replaced with improved technologies to achieve this sensitivity gain. Much better seismic isolation and test mass suspensions are responsible for the gains at lower frequencies. Higher laser power, larger test masses and improved mirror coatings lead to the improved sensitivity at mid and high frequencies. Data collecting runs with these new instruments are planned to begin in mid-2015.

  20. Sorafenib in patients with locally advanced and metastatic chordomas: a phase II trial of the French Sarcoma Group (GSF/GETO)†

    PubMed Central

    Bompas, E.; Le Cesne, A.; Tresch-Bruneel, E.; Lebellec, L.; Laurence, V.; Collard, O.; Saada-Bouzid, E.; Isambert, N.; Blay, J. Y.; Amela, E. Y.; Salas, S.; Chevreau, C.; Bertucci, F.; Italiano, A.; Clisant, S.; Penel, N.

    2015-01-01

    Background There is no consensual treatment of locally advanced or metastatic chordomas. Patients and methods We conducted a multicenter, open-label, uncontrolled phase II trial of sorafenib (800 mg/day). The primary end point was the 9-month progression-free rate according to RECIST 1.1. All patients had documented progressive disease at the time of study entry. Results Twenty-seven patients were enrolled between May 2011 and January 2014. The median age was 64 (range, 30–86) years. There were 17 men and 10 women. Twelve patients had been previously treated with chemotherapy and molecularly targeted agents. The maximum toxicity grade per patient was grade 3 in 21 cases (77.8%) and grade 4 in 4 cases (14.8%). Sorafenib provided an intent-to-treat best objective response of 1/27 [3.7%; 95% confidence interval (CI) 0.1% to 19.0%], a 9-month progression-free rate of 73.0% (95% CI 46.1–88.0) and a 12-month overall survival rate of 86.5% (95% CI 55.8–96.5). Survival curves were similar in pretreated and not pretreated patients. Discussion Additional clinical trials further exploring sorafenib as a treatment of locally advanced or metastatic chordomas are warranted. PMID:26202596

  1. Terahertz detectors and focal plane arrays

    NASA Astrophysics Data System (ADS)

    Rogalski, A.; Sizov, F.

    2011-09-01

    Terahertz (THz) technology is one of emerging technologies that will change our life. A lot of attractive applications in security, medicine, biology, astronomy, and non-destructive materials testing have been demonstrated already. However, the realization of THz emitters and receivers is a challenge because the frequencies are too high for conventional electronics and the photon energies are too small for classical optics. As a result, THz radiation is resistant to the techniques commonly employed in these well established neighbouring bands. In the paper, issues associated with the development and exploitation of THz radiation detectors and focal plane arrays are discussed. Historical impressive progress in THz detector sensitivity in a period of more than half century is analyzed. More attention is put on the basic physical phenomena and the recent progress in both direct and heterodyne detectors. After short description of general classification of THz detectors, more details concern Schottky barrier diodes, pair braking detectors, hot electron mixers and field-effect transistor detectors, where links between THz devices and modern technologies such as micromachining are underlined. Also, the operational conditions of THz detectors and their upper performance limits are reviewed. Finally, recent advances in novel nanoelectronic materials and technologies are described. It is expected that applications of nanoscale materials and devices will open the door for further performance improvement in THz detectors.

  2. The next detectors for gravitational wave astronomy

    NASA Astrophysics Data System (ADS)

    Blair, David; Ju, Li; Zhao, ChunNong; Wen, LinQing; Miao, HaiXing; Cai, RongGen; Gao, JiangRui; Lin, XueChun; Liu, Dong; Wu, Ling-An; Zhu, ZongHong; Hammond, Giles; Paik, Ho Jung; Fafone, Viviana; Rocchi, Alessio; Blair, Carl; Ma, YiQiu; Qin, JiaYi; Page, Michael

    2015-12-01

    This paper focuses on the next detectors for gravitational wave astronomy which will be required after the current ground based detectors have completed their initial observations, and probably achieved the first direct detection of gravitational waves. The next detectors will need to have greater sensitivity, while also enabling the world array of detectors to have improved angular resolution to allow localisation of signal sources. Sect. 1 of this paper begins by reviewing proposals for the next ground based detectors, and presents an analysis of the sensitivity of an 8 km armlength detector, which is proposed as a safe and cost-effective means to attain a 4-fold improvement in sensitivity. The scientific benefits of creating a pair of such detectors in China and Australia is emphasised. Sect. 2 of this paper discusses the high performance suspension systems for test masses that will be an essential component for future detectors, while sect. 3 discusses solutions to the problem of Newtonian noise which arise from fluctuations in gravity gradient forces acting on test masses. Such gravitational perturbations cannot be shielded, and set limits to low frequency sensitivity unless measured and suppressed. Sects. 4 and 5 address critical operational technologies that will be ongoing issues in future detectors. Sect. 4 addresses the design of thermal compensation systems needed in all high optical power interferometers operating at room temperature. Parametric instability control is addressed in sect. 5. Only recently proven to occur in Advanced LIGO, parametric instability phenomenon brings both risks and opportunities for future detectors. The path to future enhancements of detectors will come from quantum measurement technologies. Sect. 6 focuses on the use of optomechanical devices for obtaining enhanced sensitivity, while sect. 7 reviews a range of quantum measurement options.

  3. ALICE detector in construction phase

    NASA Astrophysics Data System (ADS)

    Peryt, Wiktor S.

    2005-09-01

    ALICE1 collaboration, which prepares one of the biggest physics experiments in the history, came into production phase of its detector. The experiment will start at LHC2 at CERN in 2007/2008. In the meantime about 1000 people from ~70 institutions are involved in this enterprise. ALICE detector consists of many sub-detectors, designed and manufactured in many laboratories and commercial firms, located mainly in Europe, but also in U.S., India, China and Korea. To assure appropriate working environment for such a specific task, strictly related to tests of particular components, measurements and assembly procedures Detector Construction Database system has been designed and implemented at CERN and at some labs involved in these activities. In this paper special attention is paid to this topic not only due to fact of innovative approach to the problem. Another reason is the group of young computer scientists (mainly students) from the Warsaw University of Technology, leaded by the author, has designed and developed the system for the whole experiment3. Another very interesting subject is the Data Acquisition System which has to fulfill very hard requirements concerning speed and high bandwidth. Required technical performance is achieved thanks to using PCI bus (usually in previous high energy physics experiments VME standard has been used) and optical links. Very general overview of the whole detector and physics goals of ALICE experiment will also be given.

  4. Study of improved resins for advanced supersonic technology composites. Part 1: Heteroaromatic polymers containing ether groups. Part 2: Curing chemistry of aromatic polymers and composite studies

    NASA Technical Reports Server (NTRS)

    Takekoshi, T.; Hillig, W. B.; Mellinger, G. A.

    1975-01-01

    Fourteen ether-containing, aromatic dianhydrides have been synthesized from N-phenyl-3 or 4-nitrophthalimide and various bisphenols. The process involves nucleophilic displacement of activated nitro groups with bisphenolate ions. Ether-containing dianhydrides were indefinitely stable in the presence of atmospheric moisture. One-step, high temperature solution polymerization of the ether-containing dianhydrides with m-phenylene diamine, 4,4'-oxydianiline and 1, 3-bis(4-aminophenoxy)benzene afforded 42 polyetherimides. The polyetherimides were all soluble in m-cresol except two which were found to be crystalline. The glass transition temperatures of the polyetherimides ranged from 178 to 277 C. Soluble polybenzimidazopyrrolones containing ether groups were also prepared from the same ether-containing dianhydrides and aromatic tetraamines by one-step solution polymerization. Using low molecular weight polyetherimides, various thermoset resin systems were developed and tested as matrices for fiber-reinforced composites. The curing chemistry involving reaction of the phthalonitrile group and the o-diaminophenyl group was found to be generally applicable to crosslinking various aromatic polymers other than polyimides.

  5. Development of a fast, fine-grained, scintillating fiber hodoscope for use in advanced detector systems for high-energy-physics research. Technical progress report, June 1, 1983-May 31, 1984

    SciTech Connect

    Borenstein, S.R.

    1983-01-01

    This report will indicate the progress made since the last report in the following categories of activity: (1) procurement of a stock of acceptable plastic scintillator perform; (2) improvements in the technique and quality control of drawing and cladding scintillating fibers; (3) fabrication of the bilayer ribbon hodoscope; (4) operation of a prototype hodoscope at the AGS; (5) software development for data acquisition; (6) preparation of an efficient optical coupling between the scintillating fiber and the photo-detector; and (7) determination of the feasibility of the Avalanche Photodiode (APD) as a photo-detector.

  6. Pelvic Lymph Node Status Assessed by 18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Low-Risk Group for Distant Recurrence in Locally Advanced Cervical Cancer: A Prospective Study

    SciTech Connect

    Kang, Sokbom; Park, Jung-Yeol; Lim, Myung-Chul; Song, Yong-Joong; Park, Se-Hyun; Kim, Seok-Ki; Chung, Dae-Chul; Seo, Sang-Soo; Kim, Joo-Young; Park, Sang-Yoon

    2011-03-01

    Purpose: To develop a prediction model to identify a low-risk group for distant recurrence in patients with locally advanced cervical cancer treated by concurrent chemoradiation. Methods and Materials: Prospectively, 62 patients with locally advanced cervical cancer were recruited as a training cohort. Clinical variables and parameters obtained from positron emission tomography (PET) and magnetic resonance imaging were analyzed by logistic regression. For the test set, 54 patients were recruited independently. To identify the low-risk group, negative likelihood ratio (LR) less than 0.2 was set to be a cutoff. Results: Among the training cohort, multivariate logistic analysis revealed that advanced International Federation of Gynecology and Obstetrics (FIGO) stage and a high serum squamous cancer cell (SCC) antigen level were significant risk factors (p = 0.015 and 0.025, respectively). Using the two parameters, criteria to determine a low-risk subset for distant recurrence were postulated: (1) FIGO Stage IIB or less and (2) pretreatment SCC < 2.4 (Model A). Positive pelvic node on PET completely predicted all cases with distant recurrence and thus was considered as another prediction model (Model B). In the test cohort, although Model A did not showed diagnostic performance, Model B completely predicted all cases with distant recurrence and showed a sensitivity of 100% with negative LR of 0. Across the training and test cohort (n = 116), the false negative rate was 0 (95% confidence interval 0%-7.6%). Conclusions: Positive pelvic node on PET is a useful marker in prediction of distant recurrence in patients with locally advanced cervical cancer who are treated with concurrent chemoradiation.

  7. GADRAS Detector Response Function.

    SciTech Connect

    Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.

    2014-11-01

    The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.

  8. The MINOS detectors

    SciTech Connect

    Habig, A.; Grashorn, E.W.; /Minnesota U., Duluth

    2005-07-01

    The Main Injector Neutrino Oscillation Search (MINOS) experiment's primary goal is the precision measurement of the neutrino oscillation parameters in the atmospheric neutrino sector. This long-baseline experiment uses Fermilab's NuMI beam, measured with a Near Detector at Fermilab, and again 735 km later using a Far Detector in the Soudan Mine Underground Lab in northern Minnesota. The detectors are magnetized iron/scintillator calorimeters. The Far Detector has been operational for cosmic ray and atmospheric neutrino data from July of 2003, the Near Detector from September 2004, and the NuMI beam started in early 2005. This poster presents details of the two detectors.

  9. The upgraded DØ detector

    NASA Astrophysics Data System (ADS)

    Abazov, V. M.; Abbott, B.; Abolins, M.; Acharya, B. S.; Adams, D. L.; Adams, M.; Adams, T.; Agelou, M.; Agram, J.-L.; Ahmed, S. N.; Ahn, S. H.; Ahsan, M.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Alverson, G.; Alves, G. A.; Anastasoaie, M.; Andeen, T.; Anderson, J. T.; Anderson, S.; Andrieu, B.; Angstadt, R.; Anosov, V.; Arnoud, Y.; Arov, M.; Askew, A.; Åsman, B.; Assis Jesus, A. C. S.; Atramentov, O.; Autermann, C.; Avila, C.; Babukhadia, L.; Bacon, T. C.; Badaud, F.; Baden, A.; Baffioni, S.; Bagby, L.; Baldin, B.; Balm, P. W.; Banerjee, P.; Banerjee, S.; Barberis, E.; Bardon, O.; Barg, W.; Bargassa, P.; Baringer, P.; Barnes, C.; Barreto, J.; Bartlett, J. F.; Bassler, U.; Bhattacharjee, M.; Baturitsky, M. A.; Bauer, D.; Bean, A.; Baumbaugh, B.; Beauceron, S.; Begalli, M.; Beaudette, F.; Begel, M.; Bellavance, A.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Besson, A.; Beuselinck, R.; Beutel, D.; Bezzubov, V. A.; Bhat, P. C.; Bhatnagar, V.; Binder, M.; Biscarat, C.; Bishoff, A.; Black, K. M.; Blackler, I.; Blazey, G.; Blekman, F.; Blessing, S.; Bloch, D.; Blumenschein, U.; Bockenthien, E.; Bodyagin, V.; Boehnlein, A.; Boeriu, O.; Bolton, T. A.; Bonamy, P.; Bonifas, D.; Borcherding, F.; Borissov, G.; Bos, K.; Bose, T.; Boswell, C.; Bowden, M.; Brandt, A.; Briskin, G.; Brock, R.; Brooijmans, G.; Bross, A.; Buchanan, N. J.; Buchholz, D.; Buehler, M.; Buescher, V.; Burdin, S.; Burke, S.; Burnett, T. H.; Busato, E.; Buszello, C. P.; Butler, D.; Butler, J. M.; Cammin, J.; Caron, S.; Bystricky, J.; Canal, L.; Canelli, F.; Carvalho, W.; Casey, B. C. K.; Casey, D.; Cason, N. M.; Castilla-Valdez, H.; Chakrabarti, S.; Chakraborty, D.; Chan, K. M.; Chandra, A.; Chapin, D.; Charles, F.; Cheu, E.; Chevalier, L.; Chi, E.; Chiche, R.; Cho, D. K.; Choate, R.; Choi, S.; Choudhary, B.; Chopra, S.; Christenson, J. H.; Christiansen, T.; Christofek, L.; Churin, I.; Cisko, G.; Claes, D.; Clark, A. R.; Clément, B.; Clément, C.; Coadou, Y.; Colling, D. J.; Coney, L.; Connolly, B.; Cooke, M.; Cooper, W. E.; Coppage, D.; Corcoran, M.; Coss, J.; Cothenet, A.; Cousinou, M.-C.; Cox, B.; Crépé-Renaudin, S.; Cristetiu, M.; Cummings, M. A. C.; Cutts, D.; da Motta, H.; Das, M.; Davies, B.; Davies, G.; Davis, G. A.; Davis, W.; De, K.; de Jong, P.; de Jong, S. J.; De La Cruz-Burelo, E.; De La Taille, C.; De Oliveira Martins, C.; Dean, S.; Degenhardt, J. D.; Déliot, F.; Delsart, P. A.; Del Signore, K.; DeMaat, R.; Demarteau, M.; Demina, R.; Demine, P.; Denisov, D.; Denisov, S. P.; Desai, S.; Diehl, H. T.; Diesburg, M.; Doets, M.; Doidge, M.; Dong, H.; Doulas, S.; Dudko, L. V.; Duflot, L.; Dugad, S. R.; Duperrin, A.; Dvornikov, O.; Dyer, J.; Dyshkant, A.; Eads, M.; Edmunds, D.; Edwards, T.; Ellison, J.; Elmsheuser, J.; Eltzroth, J. T.; Elvira, V. D.; Eno, S.; Ermolov, P.; Eroshin, O. V.; Estrada, J.; Evans, D.; Evans, H.; Evdokimov, A.; Evdokimov, V. N.; Fagan, J.; Fast, J.; Fatakia, S. N.; Fein, D.; Feligioni, L.; Ferapontov, A. V.; Ferbel, T.; Ferreira, M. J.; Fiedler, F.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Fleck, I.; Fitzpatrick, T.; Flattum, E.; Fleuret, F.; Flores, R.; Foglesong, J.; Fortner, M.; Fox, H.; Franklin, C.; Freeman, W.; Fu, S.; Fuess, S.; Gadfort, T.; Galea, C. F.; Gallas, E.; Galyaev, E.; Gao, M.; Garcia, C.; Garcia-Bellido, A.; Gardner, J.; Gavrilov, V.; Gay, A.; Gay, P.; Gelé, D.; Gelhaus, R.; Genser, K.; Gerber, C. E.; Gershtein, Y.; Gillberg, D.; Geurkov, G.; Ginther, G.; Gobbi, B.; Goldmann, K.; Golling, T.; Gollub, N.; Golovtsov, V.; Gómez, B.; Gomez, G.; Gomez, R.; Goodwin, R.; Gornushkin, Y.; Gounder, K.; Goussiou, A.; Graham, D.; Graham, G.; Grannis, P. D.; Gray, K.; Greder, S.; Green, D. R.; Green, J.; Green, J. A.; Greenlee, H.; Greenwood, Z. D.; Gregores, E. M.; Grinstein, S.; Gris, Ph.; Grivaz, J.-F.; Groer, L.; Grünendahl, S.; Grünewald, M. W.; Gu, W.; Guglielmo, J.; Gupta, A.; Gurzhiev, S. N.; Gutierrez, G.; Gutierrez, P.; Haas, A.; Hadley, N. J.; Haggard, E.; Haggerty, H.; Hagopian, S.; Hall, I.; Hall, R. E.; Han, C.; Han, L.; Hance, R.; Hanagaki, K.; Hanlet, P.; Hansen, S.; Harder, K.; Harel, A.; Harrington, R.; Hauptman, J. M.; Hauser, R.; Hays, C.; Hays, J.; Hazen, E.; Hebbeker, T.; Hebert, C.; Hedin, D.; Heinmiller, J. M.; Heinson, A. P.; Heintz, U.; Hensel, C.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hobbs, J. D.; Hoeneisen, B.; Hohlfeld, M.; Hong, S. J.; Hooper, R.; Hou, S.; Houben, P.; Hu, Y.; Huang, J.; Huang, Y.; Hynek, V.; Huffman, D.; Iashvili, I.; Illingworth, R.; Ito, A. S.; Jabeen, S.; Jacquier, Y.; Jaffré, M.; Jain, S.; Jain, V.; Jakobs, K.; Jayanti, R.; Jenkins, A.; Jesik, R.; Jiang, Y.; Johns, K.; Johnson, M.; Johnson, P.; Jonckheere, A.; Jonsson, P.; Jöstlein, H.; Jouravlev, N.; Juarez, M.; Juste, A.; Kaan, A. P.; Kado, M. M.; Käfer, D.; Kahl, W.; Kahn, S.; Kajfasz, E.

    2006-09-01

    The DØ experiment enjoyed a very successful data-collection run at the Fermilab Tevatron collider between 1992 and 1996. Since then, the detector has been upgraded to take advantage of improvements to the Tevatron and to enhance its physics capabilities. We describe the new elements of the detector, including the silicon microstrip tracker, central fiber tracker, solenoidal magnet, preshower detectors, forward muon detector, and forward proton detector. The uranium/liquid-argon calorimeters and central muon detector, remaining from Run I, are discussed briefly. We also present the associated electronics, triggering, and data acquisition systems, along with the design and implementation of software specific to DØ.

  10. Working Group 7 Summary

    SciTech Connect

    Nagaitsev S.; Berg J.

    2012-06-10

    The primary subject of working group 7 at the 2012 Advanced Accelerator Concepts Workshop was muon accelerators for a muon collider or neutrino factory. Additionally, this working group included topics that did not fit well into other working groups. Two subjects were discussed by more than one speaker: lattices to create a perfectly integrable nonlinear lattice, and a Penning trap to create antihydrogen.

  11. Neutron Detector Waveform Digitization

    NASA Astrophysics Data System (ADS)

    Toebbe, Jonathan; Gray, Fred; Grafil, Elliot; Greife, Uwe

    2010-11-01

    In the frame of a DoE Office of Nuclear Energy funded collaboration to design a next generation neutron elastic and inelastic scattering experiment, the Colorado School of Mines/Regis University group is responsible for developing and testing neutron detectors, pulse shape discrimination and read-out methods. This contribution will describe the test setup based on an n-ToF neutron selection using a ^244Cm-^13C source and the Regis Digitizer. Results on pulse shape discrimination from waveform digitization will be compared to other commercially available discrimination methods. We will also present our efforts to explore different types of algorithm for extraction of neutron assignment probabilities from the collected waveforms.

  12. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group.

    PubMed

    Seddon, J M; Ajani, U A; Sperduto, R D; Hiller, R; Blair, N; Burton, T C; Farber, M D; Gragoudas, E S; Haller, J; Miller, D T

    1994-11-01

    OBJECTIVE--To evaluate the relationships between dietary intake of carotenoids and vitamins A, C, and E and the risk of neovascular age-related macular degeneration (AMD), the leading cause of irreversible blindness among adults. DESIGN--The multicenter Eye Disease Case-Control Study. SETTING--Five ophthalmology centers in the United States. PATIENTS--A total of 356 case subjects who were diagnosed with the advanced stage of AMD within 1 year prior to their enrollment, aged 55 to 80 years, and residing near a participating clinical center. The 520 control subjects were from the same geographic areas as case subjects, had other ocular diseases, and were frequency-matched to cases according to age and sex. MAIN OUTCOME MEASURES--The relative risk for AMD was estimated according to dietary indicators of antioxidant status, controlling for smoking and other risk factors, by using multiple logistic-regression analyses. RESULTS--A higher dietary intake of carotenoids was associated with a lower risk for AMD. Adjusting for other risk factors for AMD, we found that those in the highest quintile of carotenoid intake had a 43% lower risk for AMD compared with those in the lowest quintile (odds ratio, 0.57; 95% confidence interval, 0.35 to 0.92; P for trend = .02). Among the specific carotenoids, lutein and zeaxanthin, which are primarily obtained from dark green, leafy vegetables, were most strongly associated with a reduced risk for AMD (P for trend = .001). Several food items rich in carotenoids were inversely associated with AMD. In particular, a higher frequency of intake of spinach or collard greens was associated with a substantially lower risk for AMD (P for trend < .001). The intake of preformed vitamin A (retinol) was not appreciably related to AMD. Neither vitamin E nor total vitamin C consumption was associated with a statistically significant reduced risk for AMD, although a possibly lower risk for AMD was suggested among those with higher intake of vitamin C

  13. Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report.

    PubMed

    Galardy, Paul J; Hochberg, Jessica; Perkins, Sherrie L; Harrison, Lauren; Goldman, Stanton; Cairo, Mitchell S

    2013-11-01

    Laboratory (LTLS) and clinical (CTLS) tumour lysis syndrome (TLS) are frequent complications in newly diagnosed children with advanced mature B cell non-Hodgkin lymphoma (B-NHL). Rasburicase, compared to allopurinol, results in more rapid reduction of uric acid in paediatric patients at risk for TLS. However, the safety and efficacy of rasburicase for the treatment or or prevention of TLS has not been prospectively evaluated. Children with newly diagnosed stage III-IV, bone marrow(+) and/or central nervous system(+) mature B-NHL received hydration and rasburicase prior to cytoreductive therapy. Rasburicase was safe and well-tolerated and there were no grade III-IV toxicities probably or directly related to rasburicase. Patients with an initial lactate dehydrogenase ≥2× upper limit of normal had a significantly elevated uric acid level (P = 0·005), increased incidence of TLS (P-0·005) and lower glomerular filtration rate (GFR; P < 0·001). Following rasburicase, there was only a 9% and 5% incidence of LTLS and CTLS, respectively. Furthermore, there was a significant improvement in estimated GFR from Day 0 to Day 7 following rasburicase (P = 0·0007) and only 1·3% of patients required new onset renal assisted support after rasburicase administration. A TLS strategy incorporating rasburicase prior to cytoreductive chemotherapy proved safe and effective in preventing new onset renal failure and was associated with a significant improvement in GFR. PMID:24032600

  14. Diminished production of interleukin-6 in chronic lymphocytic leukaemia (B-CLL) cells from patients at advanced stages of disease. Tampere CLL Group.

    PubMed

    Hulkkonen, J; Vilpo, J; Vilpo, L; Hurme, M

    1998-03-01

    The production of the cytokines interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) in B-CLL cells from 24 patients at different stages of chronic lymphocytic B-cell leukaemia (B-CLL) was investigated in vitro. In the majority of these cases, low spontaneous IL-6 production was measured. Mitogenic stimulation with phorbol 12-myristate 13-acetate (PMA) or PMA plus interleukin-2 (IL-2) resulted in a tremendous increase in TNF-alpha and IL-6 production in cells representing early stage (Binet A) disease. In contrast, very little, if any, production took place in cells from patients with advanced stage (Binet C) B-CLL. The results from stage B patients were intermediate. The most remarkable difference was recorded in PMA-stimulated (1 ng/ml) IL-6 production. In stimulated 72 h cultures, IL-6 concentrations were 1280 +/- 1080 pg/ml for Binet A (n = 11), 757 +/- 597 pg/ml for Binet B (n = 8) and 46.0 +/- 84.0 pg/ml for Binet C (n = 5). The differences in IL-6 production between stage C v B and stage C v A were both statistically significant (P=0.025). Similar effects, but to a lesser extent, were observed in TNF-alpha production. These results suggest that the varying capacity to produce IL-6 and TNF-alpha may play a role in B-CLL progression and in clinical manifestations of the disease. PMID:9504629

  15. Tin Can Radiation Detector.

    ERIC Educational Resources Information Center

    Crull, John L.

    1986-01-01

    Provides instructions for making tin can radiation detectors from empty aluminum cans, aluminum foil, clear plastic, copper wire, silica gel, and fine, unwaxed dental floss put together with tape or glue. Also provides suggestions for activities using the detectors. (JN)

  16. Status and perspectives of gaseous photon detectors

    NASA Astrophysics Data System (ADS)

    Di Mauro, Antonio

    2014-12-01

    This article aims at reviewing the state of the art of gaseous photon detectors for RICH applications. Emphasis will be put on THGEM based devices which represent the most advanced development among the various micro-pattern gaseous photon sensors proposed for Cherenkov imaging in very high rate environments.

  17. Optical Ranicon detectors for photon counting imaging.

    NASA Astrophysics Data System (ADS)

    Clampin, Mark; Crocker, Jim; Paresce, Francesco; Rafal, Marc

    1988-08-01

    The design and development of two detectors, known as Ranicon and advanced Ranicon, for optical photon counting imaging on ground-based telescopes are discussed. The proximity focusing, microchannel-plate stack, resistive anode, and signal processing characteristics are described. The theory behind the overall resolution of the Ranicon system is reviewed. Resolution measurements for the instruments are reported and discussed.

  18. 500 MHz neutron detector

    SciTech Connect

    Yen, Yi-Fen; Bowman, J.D.; Matsuda, Y.

    1993-12-01

    A {sup 10}B-loaded scintillation detector was built for neutron transmission measurements at the Los Alamos Neutron Scattering Center. The efficiency of the detector is nearly 100% for neutron energies from 0 to 1 keV. The neutron moderation time in the scintillator is about 250 ns and is energy independent. The detector and data processing system are designed to handle an instantaneous rate as high as 500 MHz. The active area of the detector is 40 cm in diameter.

  19. Segmented pyroelector detector

    DOEpatents

    Stotlar, S.C.; McLellan, E.J.

    1981-01-21

    A pyroelectric detector is described which has increased voltage output and improved responsivity over equivalent size detectors. The device comprises a plurality of edge-type pyroelectric detectors which have a length which is much greater than the width of the segments between the edge-type electrodes. External circuitry connects the pyroelectric detector segments in parallel to provide a single output which maintains 50 ohm impedance characteristics.

  20. Life Finder Detectors; Detector Needs and Status for Spectroscopic Biosignature Characterization

    NASA Astrophysics Data System (ADS)

    Rauscher, Bernard J.; Bolcar, Matthew R.; Clampin, Mark; Domagal-Goldman, Shawn; McElwain, Michael W.; Moseley, Samuel H.; Stahle, Carl; Stark, Christopher C.; Thronson, Harley A.

    2016-01-01

    The search for life on other worlds looms large in NASA's future. Outside our solar system, direct spectroscopic biosignature characterization using very large UV-Optical-IR telescopes with coronagraphs or starshades is a core technique to both AURA's High Definition Space Telescope (HDST) concept and NASA's 30-year strategic plan. These giant space observatories require technological advancements in several areas, one of which is detectors. In this presentation, we review the detector requirements for spectroscopic biosignature characterization and discuss the status of some existing and proposed detector technologies for meeting them.

  1. Gamma ray detector shield

    DOEpatents

    Ohlinger, R.D.; Humphrey, H.W.

    1985-08-26

    A gamma ray detector shield comprised of a rigid, lead, cylindrical-shaped vessel having upper and lower portions with an pneumatically driven, sliding top assembly. Disposed inside the lead shield is a gamma ray scintillation crystal detector. Access to the gamma detector is through the sliding top assembly.

  2. NUV Detector Dark Monitor

    NASA Astrophysics Data System (ADS)

    Zheng, Wei

    2010-09-01

    Perform routine monitoring of MAMA detector dark current. The main purpose isto look for evidence of a change in the dark rates, both to track on-orbit timedependence and to check for a detector problem developing. The spatial distribution of dark rates on the detector and the effect of SAA will also be studied.

  3. NUV Detector Dark Monitor

    NASA Astrophysics Data System (ADS)

    Cox, Colin

    2011-10-01

    Perform routine monitoring of MAMA detector dark current. The main purpose isto look for evidence of a change in the dark rates, both to track on-orbit timedependence and to check for a detector problem developing. The spatial distribution of dark rates on the detector and the effect of SAA will also be studied.

  4. NUV Detector Dark Monitor

    NASA Astrophysics Data System (ADS)

    Ely, Justin

    2012-10-01

    Perform routine monitoring of MAMA detector dark current. The main purpose isto look for evidence of a change in the dark rates, both to track on-orbit timedependence and to check for a detector problem developing. The spatial distribution of dark rates on the detector and the effect of SAA will also be studied.

  5. NUV Detector Dark Monitor

    NASA Astrophysics Data System (ADS)

    Ely, Justin

    2013-10-01

    Perform routine monitoring of MAMA detector dark current. The main purpose isto look for evidence of a change in the dark rates, both to track on-orbit timedependence and to check for a detector problem developing. The spatial distribution of dark rates on the detector and the effect of SAA will also be studied.

  6. Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

    PubMed Central

    Egloff, Ann Marie; Lee, Ju-Whei; Langer, Corey J.; Quon, Harry; Vaezi, Alec; Grandis, Jennifer R.; Seethala, Raja R.; Wang, Lin; Shin, Dong M.; Argiris, Athanassios; Yang, Donghua; Mehra, Ranee; Ridge, John Andrew; Patel, Urjeet A.; Burtness, Barbara A.; Forastiere, Arlene A.

    2014-01-01

    PURPOSE Cisplatin or cetuximab combined with radiotherapy (RT) each yield superior survival in locally advanced squamous cell head and neck cancer (LA-SCCHN) compared to RT alone. E3303 evaluated the triple combination. EXPERIMENTAL DESIGN Patients with stage IV unresectable LA-SCCHN received a loading dose of cetuximab (400mg/m2) followed by 250mg/m2/week and cisplatin 75mg/m2 q 3 weeks x3 cycles concurrent with standard fractionated RT. In the absence of disease progression or unacceptable toxicity, patients continued maintenance cetuximab for 6–12 months. Primary endpoint was 2-year progression-free survival (PFS). Patient tumor and blood correlates, including tumor human papillomavirus (HPV) status, were evaluated for association with survival. RESULTS Sixty-nine patients were enrolled; 60 proved eligible and received protocol treatment. Oropharyngeal (OP) primaries constituted the majority (66.7%), stage T4 48.3% and N2–3 91.7%. Median RT dose delivered was 70 Gy, 71.6% received all 3 cycles of cisplatin and 74.6% received maintenance cetuximab. Median PFS was 19.4 months, 2-year PFS 47% (95%CI: 33–61%). 2-year overall survival (OS) was 66% (95%CI: 53–77%); median OS was not reached. Response rate was 66.7%. Most common grade ≥3 toxicities included mucositis (55%), dysphagia (46%) and neutropenia (26%); one attributable grade 5 toxicity occurred. Only tumor HPV status was significantly associated with survival. HPV was evaluable in 29 tumors; 10 (all OP) were HPV+. HPV+ patients had significantly longer OS and PFS (p=0.004 and p=0.036, respectively). CONCLUSIONS Concurrent cetuximab, cisplatin and RT were well-tolerated and yielded promising 2-year PFS and OS in LA-SCCHN with improved survival for patients with HPV+ tumors. PMID:25107914

  7. Wideband 1.064 micrometer detector evaluation

    NASA Technical Reports Server (NTRS)

    Green, S. I.

    1975-01-01

    The performance of several candidate detectors for use as communications detectors in a 400 Mbps 1.064 micrometers laser communication system was evaluated. The results of communication system Bit Error Rate (BER) testing for the best detector of each type are summarized. Complete testing data of each type detector is presented. The 400 Mbps 1.064 micrometers communication system receiver test bed is described. The best communication system results for each detector type are included. Performance comparisons are made at 0.000001 BER, the specification level chosen for satellite laser communication links. The data is presented in two groups. The first indicates the best performance levels that can be expected on normal space laser communication system operation. The second cites the best performance levels which can be achieved by focusing the signal to diffraction limited spots on the photosensitive area.

  8. Nuclear Electronics: Superconducting Detectors and Processing Techniques

    NASA Astrophysics Data System (ADS)

    Polushkin, Vladimir

    2004-06-01

    With the commercialisation of superconducting particles and radiation detectors set to occur in the very near future, nuclear analytical instrumentation is taking a big step forward. These new detectors have a high degree of accuracy, stability and speed and are suitable for high-density multiplex integration in nuclear research laboratories and astrophysics. Furthermore, superconducting detectors can also be successfully applied to food safety, airport security systems, medical examinations, doping tests & forensic investigations. This book is the first to address a new generation of analytical tools based on new superconductor detectors demonstrating outstanding performance unsurpassed by any other conventional devices. Presenting the latest research and development in nanometer technologies and biochemistry this book: * Discusses the development of nuclear sensing techniques. * Provides guidance on the design and use of the next generation of detectors. * Describes cryogenic detectors for nuclear measurements and spectrometry. * Covers primary detectors, front-end readout electronics and digital signal processing. * Presents applications in nanotechnology and modern biochemistry including DNA sequencing, proteinomics, microorganisms. * Features examples of two applications in X-ray electron probe nanoanalysis and time-of-flight mass spectrometry. This comprehensive treatment is the ideal reference for researchers, industrial engineers and graduate students involved in the development of high precision nuclear measurements, nuclear analytical instrumentation and advanced superconductor primary sensors. This book will also appeal to physicists, electrical and electronic engineers in the nuclear industry.

  9. Successful laparoscopic distal gastrectomy with D2 lymph node dissection preserving the common hepatic artery branched from the left gastric artery for advanced gastric cancer with an Adachi type VI (group 26) vascular anomaly.

    PubMed

    Goto, Hironobu; Yasuda, Takashi; Oshikiri, Taro; Imanishi, Tatsuya; Yamashita, Hironori; Oyama, Masato; Kakinoki, Keitaro; Ohara, Tadayuki; Sendo, Hiroyoshi; Fujino, Yasuhiro; Tominaga, Masahiro; Kakeji, Yoshihiro

    2016-12-01

    We report a case of successful laparoscopic distal gastrectomy with D2 lymph node dissection preserving the common hepatic artery branched from the left gastric artery for advanced gastric cancer with an Adachi type VI (group 26) vascular anomaly. A 76-year-old female patient was admitted with a diagnosis of advanced gastric cancer at the anterior wall to the lesser curvature of the antrum (cT3N0M0 cStage IIA). Dynamic computed tomography showed the ectopia of the common hepatic artery branched from the left gastric artery. We made a diagnosis of an Adachi type VI (group 26) vascular anomaly and performed the abovementioned operation. In this anomaly pattern, scrupulous attention is required to remove the suprapancreatic lymph nodes because the portal vein is located immediately dorsal to those lymph nodes and is at increased risk for the injury in this situation. The common hepatic artery is branched from the left gastric artery, and the hepatic perfusion from the superior mesenteric artery is not present in group 26. Planning to preserve the artery will improve safety when it is possible oncologically. There were no postoperative complications, and the patient was discharged 9 days after the operation. To our knowledge, the present case is the first reported case of a laparoscopic distal gastrectomy with D2 lymph node dissection with an Adachi type VI (group 26) vascular anomaly. Preoperative diagnostic imaging is very important to prevent surgical complications because the reliable identification of vascular anomaly during an operation is very difficult. PMID:27259578

  10. Multi-segment detector

    NASA Technical Reports Server (NTRS)

    George, Peter K. (Inventor)

    1978-01-01

    A plurality of stretcher detector segments are connected in series whereby detector signals generated when a bubble passes thereby are added together. Each of the stretcher detector segments is disposed an identical propagation distance away from passive replicators wherein bubbles are replicated from a propagation path and applied, simultaneously, to the stretcher detector segments. The stretcher detector segments are arranged to include both dummy and active portions thereof which are arranged to permit the geometry of both the dummy and active portions of the segment to be substantially matched.

  11. [A comparative study between low-dose and high-dose medroxyprogesterone acetate (MPA) in the treatment of advanced and recurrent breast cancer--in relation to dose, serum concentration and response. Osaka Breast Cancer Research Group].

    PubMed

    Furukawa, J; Yayoi, E; Takatsuka, Y; Aikawa, T; Maeura, Y; Kobayashi, T; Miyauchi, K; Kotsuma, Y

    1997-05-01

    A prospective randomized study was carried out to evaluate the effectiveness of MPA in the treatment of breast cancer by comparing low dose (600 mg/day) with high dose (1,200 mg/day) of MPA. In 35 evaluable cases, the response rate to treatment was 40.0% (8/20) with low dose MPA and 26.7% (4/15) with high dose MPA. There was no significant difference between the two groups. The serum MPA concentration measured by high-performance liquid chromatography (HPLC) assay was 23.2 +/- 17.6 ng/ml in the low-dose group and 89.5 +/- 56.7 ng/ml in the high-dose group. Intrapatient variability in serum MPA concentration was relatively stable, but interpatient variability was large. No correlation was found between the response rate and serum MPA concentration. The above results indicate that a low dose of MPA (600 mg/day) is a useful treatment with high effectiveness and safety in advanced and recurrent breast cancer patients. Though no exact data on the optimal serum concentration could not be obtained, it was obvious that a successful response cannot be expected from a serum MPA concentration of less than 17 ng/ml, which was the average serum concentration in NC and PD patients of the low-dose group. PMID:9170519

  12. High-energy detector

    DOEpatents

    Bolotnikov, Aleksey E.; Camarda, Giuseppe; Cui, Yonggang; James, Ralph B.

    2011-11-22

    The preferred embodiments are directed to a high-energy detector that is electrically shielded using an anode, a cathode, and a conducting shield to substantially reduce or eliminate electrically unshielded area. The anode and the cathode are disposed at opposite ends of the detector and the conducting shield substantially surrounds at least a portion of the longitudinal surface of the detector. The conducting shield extends longitudinally to the anode end of the detector and substantially surrounds at least a portion of the detector. Signals read from one or more of the anode, cathode, and conducting shield can be used to determine the number of electrons that are liberated as a result of high-energy particles impinge on the detector. A correction technique can be implemented to correct for liberated electron that become trapped to improve the energy resolution of the high-energy detectors disclosed herein.

  13. Phase II Study of the Addition of Bevacizumab to Standard Chemoradiation for Loco-regionally Advanced Nasopharyngeal Carcinoma: Radiation Therapy Oncology Group (RTOG) Trial 0615

    PubMed Central

    Lee, Nancy Y.; Zhang, Ed; Pfister, David. G.; Kim, John; Garden, Adam. S.; Mechalakos, James; Hu, Kenneth; Le, Quynh T.; Colevas, A. Dimitrios; Glisson, Bonnie S.; Chan, Anthony T.C.; Ang, K. Kian

    2016-01-01

    Purpose We sought to improve the outcomes for loco-regionally advanced nasopharyngeal carcinoma (NPC) by testing the feasibility/safety of adding bevacizumab to chemoradiation. Patients/Methods Eligible patients with ≥T2b and/or positive node(s) were prescribed 3 cycles of bevacizumab (15 mg/kg) and cisplatin (100 mg/m2) both given on days 1, 22, and 43 of radiation (70 Gy) using IMRT delivered over 33 days on a daily basis, Monday through Friday. This is followed by 3 cycles of bevacizumab (15 mg/kg), cisplatin (80 mg/m2) both were given on days 64, 85, and 106 and fluorouracil (1000 mg/m2/d) on days 64–67, 85–88, 106–109 after radiation. The primary endpoint was to evaluate the safety of the addition of bevacizumab to chemoradiation, specifically looking at treatment-related Grade 4 hemorrhage and/or any Grade 5 adverse event in the first year. Toxicity during and after treatment were collected along with tumor control endpoints. The analysis was done per protocol. This protocol has completed its target accrual. Results There were a total of 46 patients enrolled in this study of whom 44 patients were eligible for analysis. No grade 3–4 hemorrhage or grade 5 adverse events were observed; 9 patients (20.5%) experienced grade 1–2 hemorrhage. Grade 4 adverse events were experienced by the following numbers of patients: leukopenia NOS – 6; lymphopenia – 5; neutrophil count – 5; pharyngolaryngeal pain – 2; hemoglobin – 1; infection with grade 3–4 neutrophils (blood) – 1; infection with grade 3–4 neutrophils [skin (cellulitis)] – 1; tinnitus – 1; thrombosis – 1; radiation mucositis – 1. The most common grade 3 adverse events were radiation mucositis – 33; dysphagia – 25; and mucositis/stomatitis (clinical exam) (pharynx) – 15. Two patients experienced late grade 3 xerostomia. Other late grade 3 adverse events were: dysphagia – 5; hearing impaired – 3; neuralgia NOS – 2; constitutional symptoms (other) – 1; dehydration

  14. ISABELLE. Volume 4. Detector R and D

    SciTech Connect

    Not Available

    1981-01-01

    Workshop participants were asked to assess the current status of detector R and D in terms of the specific needs for ISABELLE experiments: the demands of high particle rates, extremely selective triggers on complex and rare events, and the economics of large detector systems. The detailed results of working groups convened to consider specific areas of detector development are presented. The key points of this assessment, as regards the continuing R and D program for ISABELLE are summarized here. Twenty-six items from the volume were prepared separately for the data base, along with five items previously prepared. (GHT)

  15. Detector developments at DESY.

    PubMed

    Wunderer, Cornelia B; Allahgholi, Aschkan; Bayer, Matthias; Bianco, Laura; Correa, Jonathan; Delfs, Annette; Göttlicher, Peter; Hirsemann, Helmut; Jack, Stefanie; Klyuev, Alexander; Lange, Sabine; Marras, Alessandro; Niemann, Magdalena; Pithan, Florian; Reza, Salim; Sheviakov, Igor; Smoljanin, Sergej; Tennert, Maximilian; Trunk, Ulrich; Xia, Qingqing; Zhang, Jiaguo; Zimmer, Manfred; Das, Dipayan; Guerrini, Nicola; Marsh, Ben; Sedgwick, Iain; Turchetta, Renato; Cautero, Giuseppe; Giuressi, Dario; Menk, Ralf; Khromova, Anastasiya; Pinaroli, Giovanni; Stebel, Luigi; Marchal, Julien; Pedersen, Ulrik; Rees, Nick; Steadman, Paul; Sussmuth, Mark; Tartoni, Nicola; Yousef, Hazem; Hyun, HyoJung; Kim, KyungSook; Rah, Seungyu; Dinapoli, Roberto; Greiffenberg, Dominic; Mezza, Davide; Mozzanica, Aldo; Schmitt, Bernd; Shi, Xintian; Krueger, Hans; Klanner, Robert; Schwandt, Joem; Graafsma, Heinz

    2016-01-01

    With the increased brilliance of state-of-the-art synchrotron radiation sources and the advent of free-electron lasers (FELs) enabling revolutionary science with EUV to X-ray photons comes an urgent need for suitable photon imaging detectors. Requirements include high frame rates, very large dynamic range, single-photon sensitivity with low probability of false positives and (multi)-megapixels. At DESY, one ongoing development project - in collaboration with RAL/STFC, Elettra Sincrotrone Trieste, Diamond, and Pohang Accelerator Laboratory - is the CMOS-based soft X-ray imager PERCIVAL. PERCIVAL is a monolithic active-pixel sensor back-thinned to access its primary energy range of 250 eV to 1 keV with target efficiencies above 90%. According to preliminary specifications, the roughly 10 cm × 10 cm, 3.5k × 3.7k monolithic sensor will operate at frame rates up to 120 Hz (commensurate with most FELs) and use multiple gains within 27 µm pixels to measure 1 to ∼100000 (500 eV) simultaneously arriving photons. DESY is also leading the development of the AGIPD, a high-speed detector based on hybrid pixel technology intended for use at the European XFEL. This system is being developed in collaboration with PSI, University of Hamburg, and University of Bonn. The AGIPD allows single-pulse imaging at 4.5 MHz frame rate into a 352-frame buffer, with a dynamic range allowing single-photon detection and detection of more than 10000 photons at 12.4 keV in the same image. Modules of 65k pixels each are configured to make up (multi)megapixel cameras. This review describes the AGIPD and the PERCIVAL concepts and systems, including some recent results and a summary of their current status. It also gives a short overview over other FEL-relevant developments where the Photon Science Detector Group at DESY is involved. PMID:26698052

  16. Pillar Structured Thermal Neutron Detector

    SciTech Connect

    Nikolic, R; Conway, A; Reinhardt, C; Graff, R; Wang, T; Deo, N; Cheung, C

    2008-06-10

    This work describes an innovative solid state device structure that leverages advanced semiconductor fabrication technology to produce an efficient device for thermal neutron detection which we have coined the 'Pillar Detector'. State-of-the-art thermal neutron detectors have shortcomings in simultaneously achieving high efficiency, low operating voltage while maintaining adequate fieldability performance. By using a three dimensional silicon PIN diode pillar array filled with isotopic {sup 10}boron ({sup 10}B), a high efficiency device is theoretically possible. Here we review the design considerations for going from a 2-D to 3-D device and discuss the materials trade-offs. The relationship between the geometrical features and efficiency within our 3-D device is investigated by Monte Carlo radiation transport method coupled with finite element drift-diffusion carrier transport simulations. To benchmark our simulations and validate the predicted efficiency scaling, experimental results of a prototype device are illustrated. The fabricated pillar structures reported in this work are composed of 2 {micro}m diameter silicon pillars with a 2 {micro}m spacing and pillar height of 12 {micro}m. The pillar detector with a 12 {micro}m height achieved a thermal neutron detection efficiency of 7.3% at a reverse bias of -2 V.

  17. CALIFA Barrel prototype detector characterisation

    NASA Astrophysics Data System (ADS)

    Pietras, B.; Gascón, M.; Álvarez-Pol, H.; Bendel, M.; Bloch, T.; Casarejos, E.; Cortina-Gil, D.; Durán, I.; Fiori, E.; Gernhäuser, R.; González, D.; Kröll, T.; Le Bleis, T.; Montes, N.; Nácher, E.; Robles, M.; Perea, A.; Vilán, J. A.; Winkel, M.

    2013-11-01

    Well established in the field of scintillator detection, Caesium Iodide remains at the forefront of scintillators for use in modern calorimeters. Recent developments in photosensor technology have lead to the production of Large Area Avalanche Photo Diodes (LAAPDs), a huge advancement on traditional photosensors in terms of high internal gain, dynamic range, magnetic field insensitivity, high quantum efficiency and fast recovery time. The R3B physics programme has a number of requirements for its calorimeter, one of the most challenging being the dual functionality as both a calorimeter and a spectrometer. This involves the simultaneous detection of ∼300 MeV protons and gamma rays ranging from 0.1 to 20 MeV. This scintillator - photosensor coupling provides an excellent solution in this capacity, in part due to the near perfect match of the LAAPD quantum efficiency peak to the light output wavelength of CsI(Tl). Modern detector development is guided by use of Monte Carlo simulations to predict detector performance, nonetheless it is essential to benchmark these simulations against real data taken with prototype detector arrays. Here follows an account of the performance of two such prototypes representing different polar regions of the Barrel section of the forthcoming CALIFA calorimeter. Measurements were taken for gamma-ray energies up to 15.1 MeV (Maier-Leibnitz Laboratory, Garching, Germany) and for direct irradiation with a 180 MeV proton beam (The Svedberg Laboratoriet, Uppsala, Sweden). Results are discussed in light of complementary GEANT4 simulations.

  18. Cherenkov neutron detector for fusion reaction and runaway electron diagnostics.

    PubMed

    Cheon, MunSeong; Kim, Junghee

    2015-08-01

    A Cherenkov-type neutron detector was newly developed and neutron measurement experiments were performed at Korea Superconducting Tokamak Advanced Research. It was shown that the Cherenkov neutron detector can monitor the time-resolved neutron flux from deuterium-fueled fusion plasmas. Owing to the high temporal resolution of the detector, fast behaviors of runaway electrons, such as the neutron spikes, could be observed clearly. It is expected that the Cherenkov neutron detector could be utilized to provide useful information on runaway electrons as well as fusion reaction rate in fusion plasmas. PMID:26329194

  19. Cherenkov neutron detector for fusion reaction and runaway electron diagnostics

    SciTech Connect

    Cheon, MunSeong Kim, Junghee

    2015-08-15

    A Cherenkov-type neutron detector was newly developed and neutron measurement experiments were performed at Korea Superconducting Tokamak Advanced Research. It was shown that the Cherenkov neutron detector can monitor the time-resolved neutron flux from deuterium-fueled fusion plasmas. Owing to the high temporal resolution of the detector, fast behaviors of runaway electrons, such as the neutron spikes, could be observed clearly. It is expected that the Cherenkov neutron detector could be utilized to provide useful information on runaway electrons as well as fusion reaction rate in fusion plasmas.

  20. A high-efficiency focusing Cherenkov radiation detector

    SciTech Connect

    Lewis, K.; Moran, M.J.; Hall, J. ); Graser, M. )

    1992-03-01

    A new design uses advanced technology to produce an efficient, high-bandwidth Cherenkov detector for relativistic charged particles. The detector consists of a diamond-lathe machined ultraviolet-grade Lucite radiator, a parabolic focusing mirror, and a photodiode with an S-20 cathode. This article discusses some details of the detector design and describes preliminary measurements of its response characteristics. The data show the detector to have an overall gain of {approx}76 signal electrons per incident electron and a photodiode-limited response time of {approx}450 ps.

  1. Design philosophy of the Jet Propulsion Laboratory infrared detector test facility

    NASA Technical Reports Server (NTRS)

    Burns, R.; Blessinger, M. A.

    1983-01-01

    To support the development of advanced infrared remote sensing instrumentation using line and area arrays, a test facility has been developed to characterize the detectors. The necessary performance characteristics of the facility were defined by considering current and projected requirements for detector testing. The completed facility provides the desired level of detector testing capability as well as providing ease of human interaction.

  2. Simulated Group Counseling: An Experiential Training Model for Group Work.

    ERIC Educational Resources Information Center

    Romano, John L.

    1998-01-01

    Describes an experiential group training model designed for prepracticum-level counseling graduate students. Simulated Group Counseling (SCG) offers students an opportunity to experience being group members; facilitating a group; and processing the group with peers, an advanced graduate student observer, and the instructor. SGC reduces…

  3. SPECT detectors: the Anger Camera and beyond

    PubMed Central

    Peterson, Todd E.; Furenlid, Lars R.

    2011-01-01

    The development of radiation detectors capable of delivering spatial information about gamma-ray interactions was one of the key enabling technologies for nuclear medicine imaging and, eventually, single-photon emission computed tomography (SPECT). The continuous NaI(Tl) scintillator crystal coupled to an array of photomultiplier tubes, almost universally referred to as the Anger Camera after its inventor, has long been the dominant SPECT detector system. Nevertheless, many alternative materials and configurations have been investigated over the years. Technological advances as well as the emerging importance of specialized applications, such as cardiac and preclinical imaging, have spurred innovation such that alternatives to the Anger Camera are now part of commercial imaging systems. Increased computing power has made it practical to apply advanced signal processing and estimation schemes to make better use of the information contained in the detector signals. In this review we discuss the key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic. PMID:21828904

  4. SPECT detectors: the Anger Camera and beyond.

    PubMed

    Peterson, Todd E; Furenlid, Lars R

    2011-09-01

    The development of radiation detectors capable of delivering spatial information about gamma-ray interactions was one of the key enabling technologies for nuclear medicine imaging and, eventually, single-photon emission computed tomography (SPECT). The continuous sodium iodide scintillator crystal coupled to an array of photomultiplier tubes, almost universally referred to as the Anger Camera after its inventor, has long been the dominant SPECT detector system. Nevertheless, many alternative materials and configurations have been investigated over the years. Technological advances as well as the emerging importance of specialized applications, such as cardiac and preclinical imaging, have spurred innovation such that alternatives to the Anger Camera are now part of commercial imaging systems. Increased computing power has made it practical to apply advanced signal processing and estimation schemes to make better use of the information contained in the detector signals. In this review we discuss the key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic. PMID:21828904

  5. SPECT detectors: the Anger Camera and beyond

    NASA Astrophysics Data System (ADS)

    Peterson, Todd E.; Furenlid, Lars R.

    2011-09-01

    The development of radiation detectors capable of delivering spatial information about gamma-ray interactions was one of the key enabling technologies for nuclear medicine imaging and, eventually, single-photon emission computed tomography (SPECT). The continuous sodium iodide scintillator crystal coupled to an array of photomultiplier tubes, almost universally referred to as the Anger Camera after its inventor, has long been the dominant SPECT detector system. Nevertheless, many alternative materials and configurations have been investigated over the years. Technological advances as well as the emerging importance of specialized applications, such as cardiac and preclinical imaging, have spurred innovation such that alternatives to the Anger Camera are now part of commercial imaging systems. Increased computing power has made it practical to apply advanced signal processing and estimation schemes to make better use of the information contained in the detector signals. In this review we discuss the key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic.

  6. Status of LWIR HgCdTe infrared detector technology

    NASA Technical Reports Server (NTRS)

    Reine, M. B.

    1990-01-01

    The performance requirements that today's advanced Long Wavelength Infrared (LWIR) focal plane arrays place on the HgCdTe photovoltaic detector array are summarized. The theoretical performance limits for intrinsic LWIR HgCdTe detectors are reviewed as functions of cutoff wavelength and operating temperature. The status of LWIR HgCdTe photovoltaic detectors is reviewed and compared to the focal plane array (FPA) requirements and to the theoretical limits. Emphasis is placed on recent data for two-layer HgCdTe PLE heterojunction photodiodes grown at Loral with cutoff wavelengths ranging between 10 and 19 microns at temperatures of 70 to 80 K. Development trends in LWIR HgCdTe detector technology are outlined, and conclusions are drawn about the ability for photovoltaic HgCdTe detector arrays to satisfy a wide variety of advanced FPA array applications.

  7. The Martian Oasis Detector

    NASA Astrophysics Data System (ADS)

    Smith, P. H.; tomasko, M. G.; McEwen, A.; Rice, J.

    2000-07-01

    The next phase of unmanned Mars missions paves the way for astronauts to land on the surface of Mars. There are lessons to be learned from the unmanned precursor missions to the Moon and the Apollo lunar surface expeditions. These unmanned missions (Ranger, Lunar Orbiter, and Surveyor) provided the following valuable information, useful from both a scientific and engineering perspective, which was required to prepare the way for the manned exploration of the lunar surface: (1) high resolution imagery instrumental to Apollo landing site selection also tremendously advanced the state of Nearside and Farside regional geology; (2) demonstrated precision landing (less than two kilometers from target) and soft landing capability; (3) established that the surface had sufficient bearing strength to support a spacecraft; and (4) examination of the chemical composition and mechanical properties of the surface. The search for extinct or extant life on Mars will follow the water. However, geomorphic studies have shown that Mars has had liquid water on its surface throughout its geologic history. A cornucopia of potential landing sites with water histories (lakes, floodplains, oceans, deltas, hydrothermal regions) presently exist. How will we narrow down site selection and increase the likelihood of finding the signs of life? One way to do this is to identify 'Martian oases.' It is known that the Martian surface is often highly fractured and some areas have karst structures that support underground caves. Much of the water that formed the channels and valley networks is thought to be frozen underground. All that is needed to create the potential for liquid water is a near surface source of heat; recent lava flows and Martian meteorites attest to the potential for volcanic activity. If we can locate even one spot where fracturing, ice, and underground heat are co-located then we have the potential for an oasis. Such a discovery could truly excite the imaginations of both the

  8. Neutrino Detectors: Challenges and Opportunities

    SciTech Connect

    Soler, F. J. P.

    2011-10-06

    This paper covers possible detector options suitable at future neutrino facilities, such as Neutrino Factories, Super Beams and Beta Beams. The Magnetised Iron Neutrino Detector (MIND), which is the baseline detector at a Neutrino Factory, will be described and a new analysis which improves the efficiency of this detector at low energies will be shown. Other detectors covered include the Totally Active Scintillating Detectors (TASD), particularly relevant for a low energy Neutrino Factory, emulsion detectors for tau detection, liquid argon detectors and megaton scale water Cherenkov detectors. Finally the requirements of near detectors for long-baseline neutrino experiments will be demonstrated.

  9. The HERMES Recoil Detector

    SciTech Connect

    Kaiser, R.

    2006-07-11

    The HERMES Collaboration is installing a new Recoil Detector to upgrade the spectrometer for measurements of hard exclusive electron/positron scattering reactions, in particular deeply virtual Compton scattering. These measurements will provide access to generalised parton distributions and hence to the localisation of quarks inside hadrons and to their orbital angular momentum. The HERMES Recoil Detector consists of three active components: a silicon detector surrounding the target cell inside the beam vacuum, a scintillating fibre tracker and a photon detector consisting of three layers of tungsten/scintillator. All three detectors are located inside a solenoidal magnetic field of 1 Tesla. The Recoil Detector was extensively tested with cosmic muons over the summer of 2005 and is being installed in the winter of 2005/6 for data taking until summer 2007.

  10. Intelligent Detector Design

    SciTech Connect

    Graf, N.A.; /SLAC

    2012-06-11

    As the complexity and resolution of imaging detectors increases, the need for detailed simulation of the experimental setup also becomes more important. Designing the detectors requires efficient tools to simulate the detector response and reconstruct the events. We have developed efficient and flexible tools for detailed physics and detector response simulation as well as event reconstruction and analysis. The primary goal has been to develop a software toolkit and computing infrastructure to allow physicists from universities and labs to quickly and easily conduct physics analyses and contribute to detector research and development. The application harnesses the full power of the Geant4 toolkit without requiring the end user to have any experience with either Geant4 or C++, thereby allowing the user to concentrate on the physics of the detector system.

  11. Detectors for Particle Radiation

    NASA Astrophysics Data System (ADS)

    Kleinknecht, Konrad

    1999-01-01

    This textbook provides a clear, concise and comprehensive review of the physical principles behind the devices used to detect charged particles and gamma rays, and the construction and performance of these many different types of detectors. Detectors for high-energy particles and radiation are used in many areas of science, especially particle physics and nuclear physics experiments, nuclear medicine, cosmic ray measurements, space sciences and geological exploration. This second edition includes all the latest developments in detector technology, including several new chapters covering micro-strip gas chambers, silicion strip detectors and CCDs, scintillating fibers, shower detectors using noble liquid gases, and compensating calorimeters for hadronic showers. This well-illustrated textbook contains examples from the many areas in science in which these detectors are used. It provides both a coursebook for students in physics, and a useful introduction for researchers in other fields.

  12. Germanium detector vacuum encapsulation

    NASA Technical Reports Server (NTRS)

    Madden, N. W.; Malone, D. F.; Pehl, R. H.; Cork, C. P.; Luke, P. N.; Landis, D. A.; Pollard, M. J.

    1991-01-01

    This paper describes an encapsulation technology that should significantly improve the viability of germanium gamma-ray detectors for a number of important applications. A specialized vacuum chamber has been constructed in which the detector and the encapsulating module are processed in high vacuum. Very high vacuum conductance is achieved within the valveless encapsulating module. The detector module is then sealed without breaking the chamber vacuum. The details of the vacuum chamber, valveless module, processing, and sealing method are presented.

  13. Detectors (4/5)

    ScienceCinema

    None

    2011-10-06

    This lecture will serve as an introduction to particle detectors and detection techniques. In the first lecture, a historic overview of particle detector development will be given. In the second lecture, some basic techniques and concepts for particle detection will be discussed. In the third lecture, the interaction of particles with matter, the basis of particle detection, will be presented. The fourth and fifth lectures will discuss different detector types used for particle tracking, energy measurement and particle identification.

  14. Detectors (5/5)

    ScienceCinema

    None

    2011-10-06

    This lecture will serve as an introduction to particle detectors and detection techniques. In the first lecture, a historic overview of particle detector development will be given. In the second lecture, some basic techniques and concepts for particle detection will be discussed. In the third lecture, the interaction of particles with matter, the basis of particle detection, will be presented. The fourth and fifth lectures will discuss different detector types used for particle tracking, energy measurement and particle identification.

  15. Grouping for Inequity

    ERIC Educational Resources Information Center

    Macqueen, Suzanne Elizabeth

    2013-01-01

    The inequity of streaming as a method of organising classes was established by research conducted in the 1960s and 1970s. While the practice produces small advantages for limited groups of students, it hinders the academic and social advancement of the majority. Although streaming has declined, new forms of achievement grouping have emerged, with…

  16. LIGO-India: expanding the international network of gravitational wave detectors

    NASA Astrophysics Data System (ADS)

    Iyer, Balasubramanian

    2015-04-01

    The first detection of Gravitational Waves (GW) by ground based detectors will open up a fundamentally new observational window to the Universe with implications for astrophysics and eventually cosmology and fundamental physics. The realization of GW astronomy requires a global network of Advanced GW detectors including upcoming observatories like KAGRA (Japan) and LIGO-India to provide good sky localization of the GW sources. LIGO-India is expected to play a key role in locating and deciphering the sources contributing to the GW symphony. The current status of LIGO-India project and the exciting future research opportunities of this ambitious Indo-US collaboration in science, technology and computation will be finally indicated. Acknowledge CISA and APS for the Award of a APS Beller Lectureship. BRI supported by the AIRBUS Group Corporate Foundation through a visiting professorship, which is part of the ``Mathematics of Complex Systems'' chair at ICTS.

  17. A Statistical Estimation Approach for Quantitative Concentrations of Compounds Lacking Authentic Standards/Surrogates Based on Linear Correlations between Directly Measured Detector Responses and Carbon Number of Different Functional Groups

    PubMed Central

    2013-01-01

    A statistical approach was investigated to estimate the concentration of compounds lacking authentic standards/surrogates (CLASS). As a means to assess the reliability of this approach, the response factor (RF) of CLASS is derived by predictive equations based on a linear regression (LR) analysis between the actual RF (by external calibration) of 18 reference volatile organic compounds (VOCs) consisting of six original functional groups and their physicochemical parameters ((1) carbon number (CN), (2) molecular weight (MW), and (3) boiling point (BP)). If the experimental bias is estimated in terms of percent difference (PD) between the actual and projected RF, the least bias for 18 VOCs is found from CN (17.9 ± 19.0%). In contrast, the PD values against MW and BP are 40.6% and 81.5%, respectively. Predictive equations were hence derived via an LR analysis between the actual RF and CN for 29 groups: (1) one group consisting of all 18 reference VOCs, (2) three out of six original functional groups, and (3) 25 groups formed randomly from the six functional groups. The applicability of this method was tested by fitting these 29 equations into each of the six original functional groups. According to this approach, the mean PD for 18 compounds dropped as low as 5.60 ± 5.63%. This approach can thus be used as a practical tool to assess the quantitative data for CLASS. PMID:23766682

  18. Adaptors for radiation detectors

    DOEpatents

    Livesay, Ronald Jason

    2014-04-22

    Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

  19. Adaptors for radiation detectors

    DOEpatents

    Livesay, Ronald Jason

    2015-07-28

    Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

  20. Detectors of gravitational waves

    NASA Astrophysics Data System (ADS)

    Pizzella, G.

    Gravitational waves Motion of test bodies in a g.w. field Energy carried by gravitational waves Gravitational-wave sources Spinning star Double-star systems Fall into a Schwarzschild black hole Radiation from gravitational collapse Gravitational-wave detectors The nonresonant detectors The resonant detectors Electromechnical transducers Piezoelectric ceramic The capacitor The inductor Data analysis The Brownian noise The back-action The wide-band noise, data analysis and optimization The resonant transducer The Wiener-Kolmogoroff filter The cross-section and the effective temperature The antenna bandwidth The gravitational-wave experiments in the world The laser interferometers The resonant detectors

  1. The CDFII Silicon Detector

    SciTech Connect

    Julia Thom

    2004-07-23

    The CDFII silicon detector consists of 8 layers of double-sided silicon micro-strip sensors totaling 722,432 readout channels, making it one of the largest silicon detectors in present use by an HEP experiment. After two years of data taking, we report on our experience operating the complex device. The performance of the CDFII silicon detector is presented and its impact on physics analyses is discussed. We have already observed measurable effects from radiation damage. These results and their impact on the expected lifetime of the detector are briefly reviewed.

  2. Photocapacitive MIS infrared detectors

    NASA Technical Reports Server (NTRS)

    Sher, A.; Lu, S. S.-M.; Moriarty, J. A.; Crouch, R. K.; Miller, W. E.

    1978-01-01

    A new class of room-temperature infrared detectors has been developed through use of metal-insulator-semiconductor (MIS) or metal-insulator-semiconductor-insulator-metal (MISIM) slabs. The detectors, which have been fabricated from Si, Ge and GaAs, rely for operation on the electrical capacitance variations induced by modulated incident radiation. The peak detectivity for a 1000-A Si MISIM detector is comparable to that of a conventional Si detector functioning in the photovoltaic mode. Optimization of the photocapacitive-mode detection sensitivity is discussed.

  3. Inexpensive solid state radiation detector

    NASA Astrophysics Data System (ADS)

    Aplin, Karen; Hastings, Peter; Harrison, R. Giles; Nicoll, Keri

    2015-04-01

    Monitoring of environmental radioactivity is of interest both within the geosciences community and to groups such as the emergency services who need to quickly assess the safety of an environment. Here we present a light weight and inexpensive detector based on solid state technology, that can be easily worn or carried, or used disposably. It responds to gamma radiation and other radioactive particles such as those from space weather and cosmic rays. Unlike traditional technology such as the Geiger counter, the detector can operate at low voltage without the need for step-up circuitry, and it can also distinguish different particle energies. It is suitable for monitoring background radioactivity from cosmic rays and radon as well as responding to higher radioactivity levels. We anticipate that the device will have a broad range of end users, from terrestrial to space applications.

  4. Final Report for the UNIVERSITY-BASED DETECTOR RESEARCH AND DEVELOPMENT FOR THE INTERNATIONAL LINEAR COLLIDER

    SciTech Connect

    Brau, James E

    2013-04-22

    The U.S Linear Collider Detector R&D program, supported by the DOE and NSF umbrella grants to the University of Oregon, made significant advances on many critical aspects of the ILC detector program. Progress advanced on vertex detector sensor development, silicon and TPC tracking, calorimetry on candidate technologies, and muon detection, as well as on beamline measurements of luminosity, energy, and polarization.

  5. Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group

    PubMed Central

    Gardini, Andrea Casadei; Scarpi, Emanuela; Marisi, Giorgia; Foschi, Francesco Giuseppe; Donati, Gabriele; Giampalma, Emanuela; Faloppi, Luca; Scartozzi, Mario; Silvestris, Nicola; Bisulli, Marcello; Corbelli, Jody; Gardini, Andrea; Barba, Giuliano La; Veneroni, Luigi; Tamberi, Stefano; Cascinu, Stefano; Frassineti, Giovanni Luca

    2016-01-01

    Hypertension (HTN) is frequently associated with the use of angiogenesis inhibitors targeting the vascular endothelial growth factor pathway and appears to be a generalized effect of this class of agent. We investigated the phenomenon in 61 patients with advanced hepatocellular carcinoma (HCC) receiving sorafenib. Blood pressure and plasma electrolytes were measured on days 1 and 15 of the treatment. Patients with sorafenib-induced HTN had a better outcome than those without HTN (disease control rate: 63.4% vs. 17.2% (p=0.001); progression-free survival 6.0 months (95% CI 3.2-10.1) vs. 2.5 months (95% CI 1.9-2.6) (p<0.001) and overall survival 14.6 months (95% CI9.7-19.0) vs. 3.9 months (95% CI 3.1-8.7) (p=0.003). Sodium levels were generally higher on day 15 than at baseline (+2.38, p<0.0001) in the group of responders (+4.95, p <0.0001) compared to patients who progressed (PD) (+0.28, p=0.607). In contrast, potassium was lower on day 14 (−0.30, p=0.0008) in the responder group (−0.58, p=0.003) than in those with progressive disease (−0.06, p=0.500). The early onset of hypertension is associated with improved clinical outcome in HCC patients treated with sorafenib. Our data are suggestive of an activation of the renin-angiotensin system in patients with advanced disease who developed HTN during sorafenib treatment. PMID:26893366

  6. Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group.

    PubMed

    Casadei Gardini, Andrea; Scarpi, Emanuela; Marisi, Giorgia; Foschi, Francesco Giuseppe; Donati, Gabriele; Giampalma, Emanuela; Faloppi, Luca; Scartozzi, Mario; Silvestris, Nicola; Bisulli, Marcello; Corbelli, Jody; Gardini, Andrea; La Barba, Giuliano; Veneroni, Luigi; Tamberi, Stefano; Cascinu, Stefano; Frassineti, Giovanni Luca

    2016-03-22

    Hypertension (HTN) is frequently associated with the use of angiogenesis inhibitors targeting the vascular endothelial growth factor pathway and appears to be a generalized effect of this class of agent. We investigated the phenomenon in 61 patients with advanced hepatocellular carcinoma (HCC) receiving sorafenib. Blood pressure and plasma electrolytes were measured on days 1 and 15 of the treatment. Patients with sorafenib-induced HTN had a better outcome than those without HTN (disease control rate: 63.4% vs. 17.2% (p=0.001); progression-free survival 6.0 months (95% CI 3.2-10.1) vs. 2.5 months (95% CI 1.9-2.6) (p<0.001) and overall survival 14.6 months (95% CI9.7-19.0) vs. 3.9 months (95% CI 3.1-8.7) (p=0.003). Sodium levels were generally higher on day 15 than at baseline (+2.38, p<0.0001) in the group of responders (+4.95, p <0.0001) compared to patients who progressed (PD) (+0.28, p=0.607). In contrast, potassium was lower on day 14 (-0.30, p=0.0008) in the responder group (-0.58, p=0.003) than in those with progressive disease (-0.06, p=0.500). The early onset of hypertension is associated with improved clinical outcome in HCC patients treated with sorafenib. Our data are suggestive of an activation of the renin-angiotensin system in patients with advanced disease who developed HTN during sorafenib treatment. PMID:26893366

  7. Gamma Detector Response and Analysis Software%u2013Detector Response Function

    2015-04-01

    Version 00 GADRAS-DRF contains a suite of capabilities related to radiation detection. Its primary function is the simulation of gamma-ray and neutron detector signals to radiation sources. It also contains limited analysis functionality. GADRAS-DRF is the public version of the full version of GADRAS with capabilities such as radiation transport and advanced analyses removed.

  8. Type II superlattice technology for LWIR detectors

    NASA Astrophysics Data System (ADS)

    Klipstein, P. C.; Avnon, E.; Azulai, D.; Benny, Y.; Fraenkel, R.; Glozman, A.; Hojman, E.; Klin, O.; Krasovitsky, L.; Langof, L.; Lukomsky, I.; Nitzani, M.; Shtrichman, I.; Rappaport, N.; Snapi, N.; Weiss, E.; Tuito, A.

    2016-05-01

    SCD has developed a range of advanced infrared detectors based on III-V semiconductor heterostructures grown on GaSb. The XBn/XBp family of barrier detectors enables diffusion limited dark currents, comparable with MCT Rule-07, and high quantum efficiencies. This work describes some of the technical challenges that were overcome, and the ultimate performance that was finally achieved, for SCD's new 15 μm pitch "Pelican-D LW" type II superlattice (T2SL) XBp array detector. This detector is the first of SCD's line of high performance two dimensional arrays working in the LWIR spectral range, and was designed with a ~9.3 micron cut-off wavelength and a format of 640 x 512 pixels. It contains InAs/GaSb and InAs/AlSb T2SLs, engineered using k • p modeling of the energy bands and photo-response. The wafers are grown by molecular beam epitaxy and are fabricated into Focal Plane Array (FPA) detectors using standard FPA processes, including wet and dry etching, indium bump hybridization, under-fill, and back-side polishing. The FPA has a quantum efficiency of nearly 50%, and operates at 77 K and F/2.7 with background limited performance. The pixel operability of the FPA is above 99% and it exhibits a stable residual non uniformity (RNU) of better than 0.04% of the dynamic range. The FPA uses a new digital read-out integrated circuit (ROIC), and the complete detector closely follows the interfaces of SCD's MWIR Pelican-D detector. The Pelican- D LW detector is now in the final stages of qualification and transfer to production, with first prototypes already integrated into new electro-optical systems.

  9. The Zero-Degree Detector System

    NASA Technical Reports Server (NTRS)

    Adams, James H.; Christl, Mark J.; Howell, Leonard W.; Kouznetsov, Evgueni

    2006-01-01

    We will report on a detector system used for accelerator measurement of nuclear fragmentation cross sections. This system consists of two detector planes, each carrying a ring of 8 detectors. Each detector has 64 pads. These two detector planes are arranged facing each other so that the matching detector pads on each plane form a two element charged particle telescope. Each of these telescopes is capable of determining the elemental identity of nuclear fragments passing through it. The system is used to measure light fragment production in the presence of heavier fragments. We will present a detailed discussion of the 64-pad detector design, the substrate design. The front-end electronics used to read out the signals is based on a custom VLSI chip developed for the Advanced Thin Ionization Calorimeter experiment which has been flown successfully twice in Antarctica. Each of these chips has 16 channels and each channel consists of a charge-sensitive preamplifier followed by a shaping amplifier and a track-and-hold circuit. The track-and-hold circuits are connected via a multiplexer to an output line driver. This allows the held signals to be presented, one-by-one via a common data line to a analog-to-digital converter. Because the output line driver can be placed in a high input impedance state when not in use, it is possible to daisy-change many chips on the same common data line. The front-end electronics and data readout scheme will be discussed in detail. The Zero Degree Detector has been used in several accelerator experiments conducted at the NASA Space Radiation Laboratory and the Alternating Gradient Synchrotron at Brookhaven National Laboratory as well as at the HIMAC accelerator in Japan. We will show examples of data taken at these accelerator runs to demonstrate how the system works.

  10. Plans for Advanced LIGO Instruments

    NASA Astrophysics Data System (ADS)

    Wilkinson, Carol

    2005-04-01

    The proposed Advanced LIGO detector will have an increase in sensitivity over initial LIGO by a factor of ten, with an increased bandwidth in the region of highest sensitivity and the ability to tune for specific astrophysical sources. Advanced LIGO will achieve the equivalent of the one-year integrated observation time of initial LIGO in just several hours, allowing observation of astrophysical gravitational waves on a regular basis. The Advanced LIGO detector will replace the existing detector at the LIGO Observatories while retaining the existing building and vacuum system infrastructure. The new instruments build on the initial LIGO Fabry-Perot Michelson Interferometer layout and take advantage of significant advances in technology since the design of initial LIGO in the 1990's. Signal strength/sensitivity will be improved by increasing the laser power, lowering optical absorption, and adding signal recycling to the Fabry-Perot arm cavities. Stray forces on the test masses will be controlled by reducing thermal noise sources in the suspensions and optics and using a multi-staged seismic isolation system with inertial sensing and feedback control. The LIGO laboratory, the LIGO Science Collaboration, and international partners have undertaken a structured program of research and development, including testing of full-scale prototypes in context. Significant progress has been made on several of the detector subsystems. The Advanced LIGO project has been through National Science Foundation peer review and the National Science Board has recommended it for funding. Based on a proposed funding start in 2007, detector installation will begin in 2010, with observations at an advanced level of commissioning in 2013.

  11. GRAVITY detector systems

    NASA Astrophysics Data System (ADS)

    Mehrgan, Leander H.; Finger, Gert; Accardo, Matteo; Lizon, Jean-Louis; Stegmeier, Joerg; Eisenhauer, Frank

    2014-07-01

    GRAVITY is a second generation instrument for the VLT Interferometer, designed to enhance the near-infrared astrometric and spectro-imaging capabilities of VLTI. It will combine the AO corrected beams of the four VLT telescopes. The GRAVITY instrument uses a total of five eAPD detectors, four of which are for wavefront sensing and one for the Fringe tracker. In addition two Hawaii2RG are used, one for the acquisition camera and one for the spectrometer. A compact bath cryostat is used for each WFS unit, one for each of the VLT Unit Telescopes. Both Hawaii2RG detectors have a cutoff wavelength of 2.5 microns. A new and unique element of GRAVITY is the use of infrared wavefront sensors. For this reason SELEX-Galileo has developed a new high speed avalanche photo diode detector for ESO. The SAPHIRA detector, which stands for Selex Avalanche Photodiodes for Highspeed Infra Red Applications, has been already evaluated by ESO. At a frame rate of 1 KHz, a read noise of less than one electron can be demonstrated. A more detailed presentation about the performance of the SPAHIRA detector will be given at this conference 1. Each SAPHIRA detector is installed in an LN2 bath cryostat. The detector stage, filter wheel and optics are mounted on the cold plate of the LN2 vessel and enclosed by a radiation shield. All seven detector systems are controlled and read out by the standard ESO NGC controller. The NGC is a controller platform which can be adapted and customized for all infrared and optical detectors. This paper will discuss specific controller modifications implemented to meet the special requirements of the GRAVITY detector systems and give an overview of the GRAVITY detector systems and their performance.

  12. Front End Spectroscopy ASIC for Germanium Detectors

    NASA Astrophysics Data System (ADS)

    Wulf, Eric

    Large-area, tracking, semiconductor detectors with excellent spatial and spectral resolution enable exciting new access to soft (0.2-5 MeV) gamma-ray astrophysics. The improvements from semiconductor tracking detectors come with the burden of high density of strips and/or pixels that require high-density, low-power, spectroscopy quality readout electronics. CMOS ASIC technologies are a natural fit to this requirement and have led to high-quality readout systems for all current semiconducting tracking detectors except for germanium detectors. The Compton Spectrometer and Imager (COSI), formerly NCT, at University of California Berkeley and the Gamma-Ray Imager/Polarimeter for Solar flares (GRIPS) at Goddard Space Flight Center utilize germanium cross-strip detectors and are on the forefront of NASA's Compton telescope research with funded missions of long duration balloon flights. The development of a readout ASIC for germanium detectors would allow COSI to replace their discrete electronics readout and would enable the proposed Gamma-Ray Explorer (GRX) mission utilizing germanium strip-detectors. We propose a 3-year program to develop and test a germanium readout ASIC to TRL 5 and to integrate the ASIC readout onto a COSI detector allowing a TRL 6 demonstration for the following COSI balloon flight. Our group at NRL led a program, sponsored by another government agency, to produce and integrate a cross-strip silicon detector ASIC, designed and fabricated by Dr. De Geronimo at Brookhaven National Laboratory. The ASIC was designed to handle the large (>30 pF) capacitance of three 10 cm^2 detectors daisy-chained together. The front-end preamplifier, selectable inverter, shaping times, and gains make this ASIC compatible with a germanium cross-strip detector as well. We therefore have the opportunity and expertise to leverage the previous investment in the silicon ASIC for a new mission. A germanium strip detector ASIC will also require precise timing of the signals at

  13. Topological detector: measuring continuous dosimetric quantities with few-element detector array

    NASA Astrophysics Data System (ADS)

    Han, Zhaohui; Brivio, Davide; Sajo, Erno; Zygmanski, Piotr

    2016-08-01

    A prototype topological detector was fabricated and investigated for quality assurance of radiation producing medical devices. Unlike a typical array or flat panel detector, a topological detector, while capable of achieving a very high spatial resolution, consists of only a few elements and therefore is much simpler in construction and more cost effective. The key feature allowing this advancement is a geometry-driven design that is customized for a specific dosimetric application. In the current work, a topological detector of two elements was examined for the positioning verification of the radiation collimating devices (jaws, MLCs, and blades etc). The detector was diagonally segmented from a rectangular thin film strip (2.5 cm  ×  15 cm), giving two contiguous but independent detector elements. The segmented area was the central portion of the strip measuring 5 cm in length. Under irradiation, signals from each detector element were separately digitized using a commercial multichannel data acquisition system. The center and size of an x-ray field, which were uniquely determined by the collimator positions, were shown mathematically to relate to the difference and sum of the two signals. As a proof of concept, experiments were carried out using slit x-ray fields ranging from 2 mm to 20 mm in size. It was demonstrated that, the collimator positions can be accurately measured with sub-millimeter precisions.

  14. Topological detector: measuring continuous dosimetric quantities with few-element detector array.

    PubMed

    Han, Zhaohui; Brivio, Davide; Sajo, Erno; Zygmanski, Piotr

    2016-08-21

    A prototype topological detector was fabricated and investigated for quality assurance of radiation producing medical devices. Unlike a typical array or flat panel detector, a topological detector, while capable of achieving a very high spatial resolution, consists of only a few elements and therefore is much simpler in construction and more cost effective. The key feature allowing this advancement is a geometry-driven design that is customized for a specific dosimetric application. In the current work, a topological detector of two elements was examined for the positioning verification of the radiation collimating devices (jaws, MLCs, and blades etc). The detector was diagonally segmented from a rectangular thin film strip (2.5 cm  ×  15 cm), giving two contiguous but independent detector elements. The segmented area was the central portion of the strip measuring 5 cm in length. Under irradiation, signals from each detector element were separately digitized using a commercial multichannel data acquisition system. The center and size of an x-ray field, which were uniquely determined by the collimator positions, were shown mathematically to relate to the difference and sum of the two signals. As a proof of concept, experiments were carried out using slit x-ray fields ranging from 2 mm to 20 mm in size. It was demonstrated that, the collimator positions can be accurately measured with sub-millimeter precisions. PMID:27452789

  15. Liquid Hydrogen: Target, Detector

    SciTech Connect

    Mulholland, G.T.; Harigel, G.G.

    2004-06-23

    In 1952 D. Glaser demonstrated that a radioactive source's radiation could boil 135 deg. C superheated-diethyl ether in a 3-mm O glass vessel and recorded bubble track growth on high-speed film in a 2-cm3 chamber. This Bubble Chamber (BC) promised improved particle track time and spatial resolution and cycling rate. Hildebrand and Nagle, U of Chicago, reported Liquid Hydrogen minimum ionizing particle boiling in August 1953. John Wood created the 3.7-cm O Liquid Hydrogen BC at LBL in January 1954. By 1959 the Lawrence Berkley Laboratory (LBL) Alvarez group's '72-inch' BC had tracks in liquid hydrogen. Within 10 years bubble chamber volumes increased by a factor of a million and spread to every laboratory with a substantial high-energy physics program. The BC, particle accelerators and special separated particle beams created a new era of High Energy Physics (HEP) experimentation. The BC became the largest most complex cryogenic installation at the world's HEP laboratories for decades. The invention and worldwide development, deployment and characteristics of these cryogenic dynamic target/detectors and related hydrogen targets are described.

  16. Interagency Advanced Power Group meeting minutes

    SciTech Connect

    Not Available

    1991-01-01

    This document contains the minutes and viewgraphs from a meeting of military personnel on the subject of power generation and distribution systems for military applications. Topics include heating and cooling systems for standard shelters, SDIO power programs, solar dynamic space power systems, hybrid solar dynamic/ photovoltaic systems, pulsed power technology, high-{Tc} superconductors, and actuators and other electronic equipment for aerospace vehicles. Attendees represented the US Air Force, Army, Navy, and NASA. (GHH)

  17. Interagency Advanced Power Group meeting minutes

    SciTech Connect

    Not Available

    1991-12-31

    This document contains the minutes and viewgraphs from a meeting of military personnel on the subject of power generation and distribution systems for military applications. Topics include heating and cooling systems for standard shelters, SDIO power programs, solar dynamic space power systems, hybrid solar dynamic/ photovoltaic systems, pulsed power technology, high-{Tc} superconductors, and actuators and other electronic equipment for aerospace vehicles. Attendees represented the US Air Force, Army, Navy, and NASA. (GHH)

  18. Silicon radiation detectors: materials and applications

    SciTech Connect

    Walton, J.T.; Haller, E.E.

    1982-10-01

    Silicon nuclear radiation detectors are available today in a large variety of sizes and types. This profusion has been made possible by the ever increasing quality and diameter silicon single crystals, new processing technologies and techniques, and innovative detector design. The salient characteristics of the four basic detector groups, diffused junction, ion implanted, surface barrier, and lithium drift are reviewed along with the silicon crystal requirements. Results of crystal imperfections detected by lithium ion compensation are presented. Processing technologies and techniques are described. Two recent novel position-sensitive detector designs are discussed - one in high-energy particle track reconstruction and the other in x-ray angiography. The unique experimental results obtained with these devices are presented.

  19. New technologies for UV detectors

    NASA Technical Reports Server (NTRS)

    Joseph, C. L.

    1993-01-01

    Several technologies are currently being developed, leading to substantial improvements in the performance of UV detectors or significant reductions in power or weight. Four technologies discussed are (1) thin-film coatings to enhance the UV sensitivity of CCD's, (2) highly innovative magnet assemblies that dramatically reduce weight and result in virtually no external flux, (3) new techniques for curving microchannel plates (MCP's) so that single plates can be used to prevent ion feedback and present highly localized charge clouds to an anode structure, and (4) high-performance alternatives to glass-based MCP's. In item (2), for example, very robust magnets are made out of rare earth materials such as samarium cobalt, and cladding magnets are employed to prevent flux from escaping from the detector into the external environment. These new ultralight magnet assemblies are able to create strong, exceptionally uniform magnetic fields for image intensification and focusing of photoelectrons. The principle advantage of such detectors is the quantum efficiencies of 70-80 percent obtained throughout ultraviolet wavelengths (900-2000 A), the highest of any device. Despite the improvements achieved under item (3), high-performance alternatives to conventional glass-based MCP's potentially offer three distinct new advantages that include (1) a 30-100-fold improvement in dynamic range resulting in correspondingly higher signal-to-noise ratios, (2) the use of pure dielectric and semiconductor materials that will not outgas contaminants that eventually destroy photocathodes, and (3) channels that have constant spacing providing long-ranged order since the plates are made using photolithography techniques from the semiconductor industry. The manufacturers of these advanced-technology MCP's, however, are a couple of years away from actually producing a functioning image intensifier. In contrast to the use of CCD's for optical, ground based observations, there is no single

  20. The CLAS Cherenkov detector

    SciTech Connect

    G. Adams; V. Burkert; R. Carl; T. Carstens; V. Frolov; L. Houghtlin; G. Jacobs; M. Kossov; M. Klusman; B. Kross; M. Onuk; J. Napolitano; J. W. Price; C. Riggs; Y. Sharabian; A. Stavinsky; L. C. Smith; W. A. Stephens; P. Stoler; W. Tuzel; K. Ullrich; A. Vlassovc; A. Weisenberger; M. Witkowski; B. Wojtekhowski; P. F. Yergin; C. Zorn

    2001-06-01

    The design, construction, and performance of the CLAS Cerenkov threshold gas detector at Jefferson Lab is described. The detector consists of 216 optical modules. Each module consists of 3 adjustable mirrors, of lightweight composite construction, a Winston light collecting cone, a 5-inch photomultiplier tube, and specially designed magnetic shielding.

  1. Particle impact location detector

    NASA Technical Reports Server (NTRS)

    Auer, S. O.

    1974-01-01

    Detector includes delay lines connected to each detector surface strip. When several particles strike different strips simultaneously, pulses generated by each strip are time delayed by certain intervals. Delay time for each strip is known. By observing time delay in pulse, it is possible to locate strip that is struck by particle.

  2. Future particle detector systems

    NASA Astrophysics Data System (ADS)

    Clark, Allan G.

    2000-09-01

    Starting with a short summary of the major new experimental physics programs, we attempt to motivate the reasons why existing general-purpose detectors at Hadron Colliders are what they are, why they are being upgraded, and why new facilities are being constructed. The CDF and ATLAS detectors are used to illustrate these motivations. Selected physics results from the CDF experiment provide evidence for limitations on the detector performance, and new physics opportunities motivate both machine and detector upgrades. This is discussed with emphasis on the improved physics reach of the CDF experiment at the Fermilab Tevatron (√s =2 TeV). From 2005, the Large Hadron Collider (LHC) at CERN will become operational at a collision energy of √s =14 TeV, seven times larger than at the Tevatron Collider. To exploit the physics capability of the LHC, several large detectors are being constructed. The detectors are significantly more complex than those at the Tevatron Collider because of physics and operational constraints. The detector design and technology of the aspects of the large general-purpose detector ATLAS is described.

  3. Arsenic activation neutron detector

    DOEpatents

    Jacobs, Eddy L.

    1981-01-01

    A detector of bursts of neutrons from a deuterium-deuteron reaction includes a quantity of arsenic adjacent a gamma detector such as a scintillator and photomultiplier tube. The arsenic is activated by the 2.5 Mev neutrons to release gamma radiation which is detected to give a quantitative representation of detected neutrons.

  4. Arsenic activation neutron detector

    DOEpatents

    Jacobs, E.L.

    1980-01-28

    A detector of bursts of neutrons from a deuterium-deuteron reaction includes a quantity of arsenic adjacent a gamma detector such as a scintillator and photomultiplier tube. The arsenic is activated by the 2.5-MeV neutrons to release gamma radiation which is detected to give a quantitative representation of detected neutrons.

  5. SCINTILLATION EXPOSURE RATE DETECTOR

    DOEpatents

    Spears, W.G.

    1960-11-01

    A radiation detector for gamma and x rays is described. The detector comprises a scintillation crystal disposed between a tantalum shield and the input of a photomultiplier tube, the crystal and the shield cooperating so that their combined response to a given quantity of radiation at various energy levels is substantially constant.

  6. Alkali ionization detector

    DOEpatents

    Hrizo, John; Bauerle, James E.; Witkowski, Robert E.

    1982-01-01

    A calibration filament containing a sodium-bearing compound is included in combination with the sensing filament and ion collector plate of a sodium ionization detector to permit periodic generation of sodium atoms for the in-situ calibration of the detector.

  7. Borner Ball Neutron Detector

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Bonner Ball Neutron Detector measures neutron radiation. Neutrons are uncharged atomic particles that have the ability to penetrate living tissues, harming human beings in space. The Bonner Ball Neutron Detector is one of three radiation experiments during Expedition Two. The others are the Phantom Torso and Dosimetric Mapping.

  8. Smoke Detectors and Legislation.

    ERIC Educational Resources Information Center

    National Fire Prevention and Control Administration (DOC), Washington, DC.

    This manual, one of a series for use in public education, provides an in-depth review of the current status of state and local smoke detector legislation. First, for the community considering a smoke detector law or ordinance, six decision points are discussed: which residential occupancy sub-classes will be affected; what the time factors are for…

  9. Recent developments in digital radiography detectors

    NASA Astrophysics Data System (ADS)

    Yorkston, John

    2007-10-01

    Medical projection radiography is currently undergoing a major transformation into the digital age. New digital X-ray detectors are providing improved image quality as well as increased functionality. These advances promise to significantly change the practice of radiology in the coming years. This review paper will describe some of the issues associated with the new digital detectors, their design, capabilities and limitations as well as a few of the promising new clinical applications being enabled by their introduction. The review will focus mainly on the new amorphous silicon flat-panel detectors but will also touch on other technologies and promising new developments that may be introduced into the clinical environment in the not too distant future.

  10. Nanomechanical resonance detector

    DOEpatents

    Grossman, Jeffrey C; Zettl, Alexander K

    2013-10-29

    An embodiment of a nanomechanical frequency detector includes a support structure and a plurality of elongated nanostructures coupled to the support structure. Each of the elongated nanostructures has a particular resonant frequency. The plurality of elongated nanostructures has a range of resonant frequencies. An embodiment of a method of identifying an object includes introducing the object to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the object. An embodiment of a method of identifying a molecular species of the present invention includes introducing the molecular species to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the molecular species.

  11. Pyroelectric detector arrays

    NASA Technical Reports Server (NTRS)

    Fripp, A. L.; Robertson, J. B.; Breckenridge, R. (Inventor)

    1982-01-01

    A pyroelectric detector array and the method for using it are described. A series of holes formed through a silicon dioxide layer on the surface of a silicon substrate forms the mounting fixture for the pyroelectric detector array. A series of nontouching strips of indium are formed around the holes to make contact with the backside electrodes and form the output terminals for individual detectors. A pyroelectric detector strip with front and back electrodes, respectively, is mounted over the strips. Biasing resistors are formed on the surface of the silicon dioxide layer and connected to the strips. A metallized pad formed on the surface of layer is connected to each of the biasing resistors and to the film to provide the ground for the pyroelectric detector array.

  12. Pyroelectric detector arrays

    NASA Technical Reports Server (NTRS)

    Fripp, A. L.; Robertson, J. B.; Breckenridge, R. A. (Inventor)

    1982-01-01

    A pryoelectric detector array and the method for making it are described. A series of holes formed through a silicon dioxide layer on the surface of a silicon substrate forms the mounting fixture for the pyroelectric detector array. A series of nontouching strips of indium are formed around the holes to make contact with the backside electrodes and form the output terminals for individual detectors. A pyroelectric detector strip with front and back electrodes, respectively, is mounted over the strip. Biasing resistors are formed on the surface of the silicon dioxide layer and connected to the strips. A metallized pad formed on the surface of the layer is connected to each of the biasing resistors and to the film to provide the ground for the pyroelectric detector array.

  13. Development of an integrated energetic neutral particle measurement system on experimental advanced full superconducting tokamak

    SciTech Connect

    Zhu, Y. B. Liu, D.; Heidbrink, W. W.; Zhang, J. Z.; Qi, M. Z.; Xia, S. B.; Wan, B. N.; Li, J. G.

    2014-11-15

    Full function integrated, compact silicon photodiode based solid state neutral particle analyzers (ssNPA) have been developed for energetic particle (EP) relevant studies on the Experimental Advanced Superconducting Tokamak (EAST). The ssNPAs will be mostly operated in advanced current mode with a few channels to be operated in conventional pulse-counting mode, aiming to simultaneously achieve individually proved ultra-fast temporal, spatial, and spectral resolution capabilities. The design details together with considerations on EAST specific engineering realities and physics requirements are presented. The system, including a group of single detectors on two vertical ports and two 16-channel arrays on a horizontal port, can provide both active and passive charge exchange measurements. ssNPA detectors, with variable thickness of ultra thin tungsten dominated foils directly deposited on the front surface, are specially fabricated and utilized to achieve about 22 keV energy resolution for deuterium particle detection.

  14. The lartge-area picosecond photo-detector (LAPPD) project

    NASA Astrophysics Data System (ADS)

    Varner, Gary

    2012-03-01

    The technological revolution that replaced the bulky Cathode Ray Tube with a wide variety of thin, reduced-cost display technologies, has yet to be realized for photosensors. Such a low-cost, robust and flexible photon detector, capable of efficient single photon measurement with good spatial and temporal resolution, would have numerous scientific, medical and industrial applications. To address the significant technological challenges of realizing such a disruptive technology, the Large Area Picosecond Photo-Detector (LAPPD) collaboration was formed, and has been strongly supported by the Department of Energy. This group leverages the inter-disciplinary capabilities and facilities at Argonne National Laboratory, the Berkeley Space Sciences Laboratory (SSL), electronics expertise at the Universities of Chicago and Hawaii, and close work with industrial partners to extend the known technologies. Advances in theory-inspired design and in-situ photocathode characterization during growth, Atomic Layer Deposition (ALD) for revolutionizing micro-channel plate fabrication, and compact, wave-form sampling CMOS ASIC readout of micro striplines are key tools toward realizing a viable LAPPD device. Progress toward a first 8" x 8" demonstrator module will be presented.

  15. Gamma ray spectroscopy in astrophysics: Future role of scintillation detectors

    NASA Technical Reports Server (NTRS)

    Kurfess, J. D.

    1978-01-01

    The future role of conventional scintillation detector telescopes for line gamma-ray astronomy is discussed. Although the energy resolution of the germanium detectors now being used by several groups is clearly desirable, the larger effective areas and higher efficiencies available with scintillation detectors is advantageous for many observations. This is particularly true for those observations of astrophysical phenomena where significant line broadening is expected.

  16. Pediatric counseling and subsequent use of smoke detectors.

    PubMed

    Miller, R E; Reisinger, K S; Blatter, M M; Wucher, F

    1982-04-01

    Effects of a brief educational and purchase program concerning home fires and smoke detectors by two pediatricians were compared to "routine" counseling without such a program using two groups each of 120 patients of well children. Inspection performed four to six weeks after the office visits showed that of 55 experimental group parents without detectors prior to the program, 26 purchased and 19 installed them correctly. No control group parents did so. PMID:7065320

  17. Arc detector uses fiber optics

    NASA Technical Reports Server (NTRS)

    Finnegan, E. J.; Leech, R. A.

    1979-01-01

    Arc detector for protecting high-power microwave klystron oscillators uses fiber optics connected to remote solid-state light-sensing circuits. Detector is more reliable, smaller, and sensitive than other systems that locate detector in waveguide.

  18. 2010 Chemical Working Group Status

    NASA Technical Reports Server (NTRS)

    Reid, Concha M.

    2010-01-01

    The Steering Group for the Interagency Advanced Power Group (IAPG) held their business meeting on November 30-December 1st in McLean, Virginia. Status reports were presented from each of the IAPG's Working Groups. These charts contain a brief summary of the IAPG Chemical Working Group's activities during 2010 and its plans for 2011.

  19. Economic analysis of a phase III clinical trial evaluating the addition of total androgen suppression to radiation versus radiation alone for locally advanced prostate cancer (Radiation Therapy Oncology Group protocol 86-10)

    SciTech Connect

    Konski, Andre . E-mail: a_konski@fccc.edu; Sherman, Eric; Krahn, Murray; Bremner, Karen; Beck, J. Robert; Watkins-Bruner, Deborah; Pilepich, Michael

    2005-11-01

    Purpose: To evaluate the cost-effectiveness of adding hormone therapy to radiation for patients with locally advanced prostate cancer, using a Monte Carlo simulation of a Markov Model. Methods and Materials: Radiation Therapy Oncology Group (RTOG) protocol 86-10 randomized patients to receive radiation therapy (RT) alone or RT plus total androgen suppression (RTHormones) 2 months before and during RT for the treatment of locally advanced prostate cancer. A Markov model was designed with Data Pro (TreeAge Software, Williamstown, MA). The analysis took a payer's perspective. Transition probabilities from one state of health (i.e., with no disease progression or with hormone-responsive metastatic disease) to another were calculated from published rates pertaining to RTOG 86-10. Patients remained in one state of health for 1 year. Utility values for each health state and treatment were obtained from the literature. Distributions were sampled at random from the treatment utilities according to a second-order Monte Carlo simulation technique. Results: The mean expected cost for the RT-only treatments was $29,240 (range, $29,138-$29,403). The mean effectiveness for the RT-only treatment was 5.48 quality-adjusted life years (QALYs) (range, 5.47-5.50). The mean expected cost for RTHormones was $31,286 (range, $31,058-$31,555). The mean effectiveness was 6.43 QALYs (range, 6.42-6.44). Incremental cost-effectiveness analysis showed RTHormones to be within the range of cost-effectiveness at $2,153/QALY. Cost-effectiveness acceptability curve analysis resulted in a >80% probability that RTHormones is cost-effective. Conclusions: Our analysis shows that adding hormonal treatment to RT improves health outcomes at a cost that is within the acceptable cost-effectiveness range.

  20. Sensors and detectors in NASA's future missions

    NASA Technical Reports Server (NTRS)

    Rubin, B.

    1978-01-01

    Advances in electronics are responsible for major improvements in NASA's sensing and detection capabilities for future space missions. Technologies such as charge-transfer devices, tunable diode lasers, millimeter and submillimeter wave solid-state receiver components, large-scale circuit integration, new electronic materials and processing techniques, and novel detector electronics are contributing to the goal of a tenfold increase in the capacity of data collection from future platforms and will be used for space exploration and utilization.

  1. Detectors for Tomorrow's Instruments

    NASA Technical Reports Server (NTRS)

    Moseley, Harvey

    2009-01-01

    Cryogenically cooled superconducting detectors have become essential tools for a wide range of measurement applications, ranging from quantum limited heterodyne detection in the millimeter range to direct searches for dark matter with superconducting phonon detectors operating at 20 mK. Superconducting detectors have several fundamental and practical advantages which have resulted in their rapid adoption by experimenters. Their excellent performance arises in part from reductions in noise resulting from their low operating temperatures, but unique superconducting properties provide a wide range of mechanisms for detection. For example, the steep dependence of resistance with temperature on the superconductor/normal transition provides a sensitive thermometer for calorimetric and bolometric applications. Parametric changes in the properties of superconducting resonators provides a mechanism for high sensitivity detection of submillimeter photons. From a practical point of view, the use of superconducting detectors has grown rapidly because many of these devices couple well to SQUID amplifiers, which are easily integrated with the detectors. These SQUID-based amplifiers and multiplexers have matured with the detectors; they are convenient to use, and have excellent noise performance. The first generation of fully integrated large scale superconducting detection systems are now being deployed. I will discuss the prospects for a new generation of instruments designed to take full advantage of the revolution in detector technology.

  2. ACCESS: Detector Performance

    NASA Astrophysics Data System (ADS)

    Morris, Matthew J.; Kaiser, M.; Rauscher, B. J.; Kimble, R. A.; Kruk, J. W.; Mott, D. B.; Wen, Y.; Foltz, R.; McCandliss, S. R.; Pelton, R. S.; Wright, E. L.; Feldman, P. D.; Moos, H. W.; Riess, A. G.; Benford, D. J.; Gardner, J. P.; Woodgate, B. E.; Bohlin, R.; Deustua, S. E.; Dixon, W. V.; Sahnow, D. J.; Kurucz, R. L.; Lampton, M.; Perlmutter, S.

    2013-01-01

    ACCESS, Absolute Color Calibration Experiment for Standard Stars, is a series of rocket-borne sub-orbital missions and ground-based experiments that will enable improvements in the precision of the astrophysical flux scale through the transfer of absolute laboratory detector standards from the National Institute of Standards and Technology (NIST) to a network of stellar standards with a calibration accuracy of 1% and a spectral resolving power of 500 across the 0.35 to 1.7 micron bandpass (overview Kaiser et al.). The flight detector and detector spare have been integrated with their electronics and flight mount. The controller electronics have been flight qualified. Vibration testing to launch loads and thermal vacuum testing of the detector, mount, and housing have been performed. The flight detector controller boards have been installed into a ruggedized flight housing. They have been successfully vacuum tested for periods significantly longer than the flight length, and components have been heat-sunk and reinforced as necessary. Thermal stability tests have been performed, and results will be presented. Goddard Space Flight Center’s Detector Characterization Lab (DCL) executed initial characterization tests for the flight detector in 2007. These were repeated in 2012, to ensure and establish baseline performance. Current lab characterization tests at Johns Hopkins are ongoing, and results will be presented. NASA sounding rocket grant NNX08AI65G supports this work.

  3. The HERMES recoil detector

    NASA Astrophysics Data System (ADS)

    Airapetian, A.; Aschenauer, E. C.; Belostotski, S.; Borisenko, A.; Bowles, J.; Brodski, I.; Bryzgalov, V.; Burns, J.; Capitani, G. P.; Carassiti, V.; Ciullo, G.; Clarkson, A.; Contalbrigo, M.; De Leo, R.; De Sanctis, E.; Diefenthaler, M.; Di Nezza, P.; Düren, M.; Ehrenfried, M.; Guler, H.; Gregor, I. M.; Hartig, M.; Hill, G.; Hoek, M.; Holler, Y.; Hristova, I.; Jo, H. S.; Kaiser, R.; Keri, T.; Kisselev, A.; Krause, B.; Krauss, B.; Lagamba, L.; Lehmann, I.; Lenisa, P.; Lu, S.; Lu, X.-G.; Lumsden, S.; Mahon, D.; Martinez de la Ossa, A.; Murray, M.; Mussgiller, A.; Nowak, W.-D.; Naryshkin, Y.; Osborne, A.; Pappalardo, L. L.; Perez-Benito, R.; Petrov, A.; Pickert, N.; Prahl, V.; Protopopescu, D.; Reinecke, M.; Riedl, C.; Rith, K.; Rosner, G.; Rubacek, L.; Ryckbosch, D.; Salomatin, Y.; Schnell, G.; Seitz, B.; Shearer, C.; Shutov, V.; Statera, M.; Steijger, J. J. M.; Stenzel, H.; Stewart, J.; Stinzing, F.; Trzcinski, A.; Tytgat, M.; Vandenbroucke, A.; Van Haarlem, Y.; Van Hulse, C.; Varanda, M.; Veretennikov, D.; Vilardi, I.; Vikhrov, V.; Vogel, C.; Yaschenko, S.; Ye, Z.; Yu, W.; Zeiler, D.; Zihlmann, B.

    2013-05-01

    For the final running period of HERA, a recoil detector was installed at the HERMES experiment to improve measurements of hard exclusive processes in charged-lepton nucleon scattering. Here, deeply virtual Compton scattering is of particular interest as this process provides constraints on generalised parton distributions that give access to the total angular momenta of quarks within the nucleon. The HERMES recoil detector was designed to improve the selection of exclusive events by a direct measurement of the four-momentum of the recoiling particle. It consisted of three components: two layers of double-sided silicon strip sensors inside the HERA beam vacuum, a two-barrel scintillating fibre tracker, and a photon detector. All sub-detectors were located inside a solenoidal magnetic field with a field strength of 1T. The recoil detector was installed in late 2005. After the commissioning of all components was finished in September 2006, it operated stably until the end of data taking at HERA end of June 2007. The present paper gives a brief overview of the physics processes of interest and the general detector design. The recoil detector components, their calibration, the momentum reconstruction of charged particles, and the event selection are described in detail. The paper closes with a summary of the performance of the detection system.

  4. Detector analysis for shallow water active sonar

    NASA Astrophysics Data System (ADS)

    Pastore, Thomas J.; Phillips, Michael E.

    2002-11-01

    SPAWAR Systems Center-San Diego, in concert with the Office of Naval Research (ONR) and Defense Advanced Research Projects Agency (DARPA) has designed and built a proof-of-concept broadband biomimetic sonar. This proof-of-concept sonar emulates a dolphin biosonar system; emitted broadband signals approximate the frequency and time domain characteristics of signals produced by echolocating dolphins, the receive system is spatially modeled after the binaural geometry of the dolphin, and signal processing algorithms incorporate sequential integration of aspect varying returns. As with any sonar, object detection in shallow water while maintaining an acceptable false alarm rate is an important problem. A comprehensive parametric analysis of detection algorithms is presented, focusing primarily on two detector strategies: a matched filter and a spectral detector. The spectral detector compares the ratio of in-band to out-of-band power, and thus functions something like a phase-incoherent matched filter. This computationally efficient detector is shown to perform well with high proportional bandwidth signals. The detector (either matched filter or spectral) is coupled with an alpha-beta tracker which maintains a running noise estimate and calculates signal excess above the estimated noise level which is compared to a fixed threshold.

  5. Cryogenic 3-D Detectors for Solar Physics

    NASA Astrophysics Data System (ADS)

    Stern, R. A.; Martinez-Galarce, D.; Rausch, A.; Shing, L.; Deiker, S.; Boerner, P.; Metcalf, T.; Cabrera, B.; Leman, S. W.; Brink, P.; Irwin, K.; Alexander, D.

    2005-05-01

    Cryogenic microcalorimeters operating in the sub-Kelvin temperature range provide non-dispersive energy resolution at optical through gamma ray energies (e.g, E/Δ E ~ 1500 at 6 keV). Microcalorimeters also have high time resolution (msec or better), and can be made into imaging arrays through SQUID multiplexing of individual pixels or employing position sensitive detector structures. The application of such "3-D" detector technology to solar physics will lead to significant advances in our understanding of magnetic reconnection in the Sun, including X-ray jet phenomena, and active region heating and dynamics. An Explorer-class solar mission within the next 5-10 years, based upon these detectors, is rapidly becoming technically feasible. LMSAL currently has an internally funded laboratory research program to investigate TES (Transition Edge Sensor) microcalorimeters; we recently saw our first X-ray photons using TES detectors supplied by NIST. In addition, we have recently been funded by NASA to begin work with NIST on position-sensitive X-ray strip detectors for solar physics applications. Finally, we are collaborating with with Stanford and NIST on a solar sounding rocket. In this presentation, we will discuss the current status of these programs and their applicability to future Explorer missions and Roadmap missions such as RAM.

  6. Detectors for the NIRCAM Instrument on JWST

    NASA Astrophysics Data System (ADS)

    Young, E. T.; Rieke, M. J.; Hall, D. N. B.; Garnett, J.; Loose, M.; Magoncelli, A.; Winters, G.

    2005-12-01

    NIRCAM is the near infrared camera for the James Webb Space Telescope. It will provide an unprecedented combination of sensitivity, wide field of view, and angular resolution between the wavelengths of 0.6 to 5 μ m. To cover this wide range, the instrument uses two versions of the Rockwell Scientific HgCdTe HAWAII-2RG detector technology. The short wavelength channel consists of a 2 x 2 mosaic of 2.5 μ m cutoff detectors, producing a 4096 x 4096 array. The mid-wavelength channel consists of a single 2048x2048 5 μ m cutoff array. For redundancy and areal coverage, the instrument has two copies of each of these channels, yielding a total of 40 megapixels on the sky. The focal plane array effort includes detector and cryogenic electronics development at Rockwell Scientific, detector packaging at the University of Arizona, and electronics development at Lockheed-Martin Advanced Technology Center. We report on the current status in all these areas. We present data that indicate the NIRCAM detectors will meet the performance goals of JWST. We also discuss testing plans for the next few months that will bring the focal plane arrays to flight technical readiness. The NIRCAM instrument is funded by NASA/GSFC under contract NAS5-02105.

  7. Methods for deploying ultra-clean detectors

    NASA Astrophysics Data System (ADS)

    Schubert, Alexis

    2008-04-01

    Next-generation underground experiments, such as searches for neutrinoless double-beta decay and dark matter experiments, will perform high-sensitivity measurements that require extremely low backgrounds. The Majo-ra-na Collaboration ootnotetextF.T. Avignone III (2007) arXiv:0711.4808v1 proposes such an experiment to search for neutrinoless double-beta decay using an array of germanium crystals enriched in ^76Ge. The design of the Majo-ra-na experiment must minimize backgrounds while meeting criteria for electrical signal quality, structural integrity, and thermal cooling characteristics. Recent work has addressed detector deployment in ultra low-background environments. Advances have been made in fabrication of radiologically pure copper parts. Prototype designs for detector support structures reduce backgrounds by minimizing component mass and making use of ultra-pure materials. This talk will describe the design and use of cryostat test-stands to investigate the performance of prototype designs for detector strings. While Majo-ra-na uses germanium detectors, the design considerations and progress made by the collaboration are applicable to other detector technologies and fields of research.

  8. Charged-coupled detector sky surveys.

    PubMed Central

    Schneider, D P

    1993-01-01

    Sky surveys have played a fundamental role in advancing our understanding of the cosmos. The current pictures of stellar evolution and structure and kinematics of our Galaxy were made possible by the extensive photographic and spectrographic programs performed in the early part of the 20th century. The Palomar Sky Survey, completed in the 1950s, is still the principal source for many investigations. In the past few decades surveys have been undertaken at radio, millimeter, infrared, and x-ray wavelengths; each has provided insights into new astronomical phenomena (e.g., quasars, pulsars, and the 3 degrees cosmic background radiation). The advent of high quantum efficiency, linear solid-state devices, in particular charged-coupled detectors, has brought about a revolution in optical astronomy. With the recent development of large-format charged-coupled detectors and the rapidly increasing capabilities of data acquisition and processing systems, it is now feasible to employ the full capabilities of electronic detectors in projects that cover an appreciable fraction of the sky. This talk reviews the first "large scale" charged-coupled detector survey. This program, designed to detect very distant quasars, reveals the powers and limitations of charged-coupled detector surveys. PMID:11607431

  9. Gravitational wave detector with cosmological reach

    NASA Astrophysics Data System (ADS)

    Dwyer, Sheila; Sigg, Daniel; Ballmer, Stefan W.; Barsotti, Lisa; Mavalvala, Nergis; Evans, Matthew

    2015-04-01

    Twenty years ago, construction began on the Laser Interferometer Gravitational-wave Observatory (LIGO). Advanced LIGO, with a factor of 10 better design sensitivity than Initial LIGO, will begin taking data this year, and should soon make detections a monthly occurrence. While Advanced LIGO promises to make first detections of gravitational waves from the nearby universe, an additional factor of 10 increase in sensitivity would put exciting science targets within reach by providing observations of binary black hole inspirals throughout most of the history of star formation, and high signal to noise observations of nearby events. Design studies for future detectors to date rely on significant technological advances that are futuristic and risky. In this paper we propose a different direction. We resurrect the idea of using longer arm lengths coupled with largely proven technologies. Since the major noise sources that limit gravitational wave detectors do not scale trivially with the length of the detector, we study their impact and find that 40 km arm lengths are nearly optimal, and can incorporate currently available technologies to detect gravitational wave sources at cosmological distances (z ≳7 ) .

  10. LHC detector upgrades

    SciTech Connect

    Dan Green

    2003-09-15

    The LHC detectors are well into their construction phase. The LHC schedule shows first beam to ATLAS and CMS in 2007. Because the LHC accelerator has begun to plan for a ten fold increase in LHC design luminosity (the SLHC or super LHC) it is none too soon to begin to think about the upgrades which will be required of the present LHC detectors. In particular, the tracking systems of ATLAS and CMS will need to be completely rebuilt. Given the time needed to do the R & D, make prototypes, and construct the new detectors and given the accelerator schedule for the SLHC, work needs to begin rather soon.

  11. Layered semiconductor neutron detectors

    DOEpatents

    Mao, Samuel S; Perry, Dale L

    2013-12-10

    Room temperature operating solid state hand held neutron detectors integrate one or more relatively thin layers of a high neutron interaction cross-section element or materials with semiconductor detectors. The high neutron interaction cross-section element (e.g., Gd, B or Li) or materials comprising at least one high neutron interaction cross-section element can be in the form of unstructured layers or micro- or nano-structured arrays. Such architecture provides high efficiency neutron detector devices by capturing substantially more carriers produced from high energy .alpha.-particles or .gamma.-photons generated by neutron interaction.

  12. Overview and Status of Advanced Interferometers for Gravitational Wave Detection

    NASA Astrophysics Data System (ADS)

    Grote, H.

    2016-05-01

    The world-wide network of km-scale laser interferometers is aiming at the detection of gravitational waves of astrophysical origin. The second generation of these instruments, called advanced detectors has been, or is in the process of being completed, and a first observational run with the Advanced LIGO interferometers has been performed late in 2015. The basic functionality of advanced detectors is discussed, along with specific features and status updates of the individual projects.

  13. Collider Detector at Fermilab (CDF): Data from B Hadrons Research

    DOE Data Explorer

    The Collider Detector at Fermilab (CDF) is a Tevatron experiment at Fermilab. The Tevatron, a powerful particle accelerator, accelerates protons and antiprotons close to the speed of light, and then makes them collide head-on inside the CDF detector. The CDF detector is used to study the products of such collisions. The CDF Physics Group is organized into six working groups, each with a specific focus. The Bottom group studies the production and decay of B hadrons. Their public web page makes data and numerous figures available from both CDF Runs I and II.

  14. Picosecond UV single photon detectors with lateral drift field: Concept and technologies

    NASA Astrophysics Data System (ADS)

    Yakimov, M.; Oktyabrsky, S.; Murat, P.

    2015-09-01

    Group III-V semiconductor materials are being considered as a Si replacement for advanced logic devices for quite some time. Advances in III-V processing technologies, such as interface and surface passivation, large area deep submicron lithography with high-aspect ratio etching primarily driven by the metal-oxide-semiconductor field-effect transistor development can also be used for other applications. In this paper we will focus on photodetectors with the drift field parallel to the surface. We compare the proposed concept to the state-of-the-art Si-based technology and discuss requirements which need to be satisfied for such detectors to be used in a single photon counting mode in blue and ultraviolet spectral region with about 10 ps photon timing resolution essential for numerous applications ranging from high-energy physics to medical imaging.

  15. A Photon Counting Imaging Detector for NASA Exoplanet Mission

    NASA Astrophysics Data System (ADS)

    Figer, Donald

    The key objective of the proposed project is to advance the maturity of a 256x256 pixel single-photon optical imaging detector. The detector has zero read noise and is resilient against the harsh effects of radiation in space. We expect that the device will have state-of-the-art performance in other parameters, e.g., high quantum efficiency from UV to 1 #m, low dark current, etc.

  16. Issues and directions in IR detector readout electronics

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.

    1990-01-01

    An introduction to the major issues encountered in the readout of imaging detector arrays in the infrared are presented. These include circuit issues such as multiplexing, buffering, and noise, as well as materials issues. Future directions in infrared readout electronics will also be discussed. These include on-chip signal processing and advanced hybridization schemes. Finally, recent work at Columbia on 2DEG-charge coupled devices for IR detector multiplexing are described.

  17. The GEO 600 Gravitational Wave Detector: Pulsar Prospects

    NASA Astrophysics Data System (ADS)

    Woan, G.; Aufmuth, P.; Aulbert, C.; Babak, S.; Balasubramanian, R.; Barr, B. W.; Berukoff, S.; Bose, S.; Cagnoli, G.; Casey, M. M.; Churches, D.; Colacino, C. N.; Crooks, D. R. M.; Cutler, C.; Danzmann, K.; Davies, R.; Dupuis, R. J.; Elliffe, E.; Fallnich, C.; Freise, A.; Goßler, S.; Grant, A.; Grote, H.; Heinzel, G.; Hepstonstall, A.; Heurs, M.; Hewitson, M.; Hough, J.; Jennrich, O.; Kawabe, K.; Kötter, K.; Leonhardt, V.; Lück, H.; Malec, M.; McNamara, P. W.; Mossavi, K.; Mohanty, S.; Mukherjee, S.; Nagano, S.; Newton, G. P.; Owen, B. J.; Papa, M. A.; Plissi, M. V.; Quetschke, V.; Robertson, D. I.; Robertson, N. A.; Rowan, S.; Rüdiger, A.; Sathyaprakash, B. S.; Schilling, R.; Schutz, B. F.; Senior, R.; Sintes, A. M.; Skeldon, K. D.; Sneddon, P.; Stief, F.; Strain, K. A.; Taylor, I.; Torrie, C. I.; Vecchio, A.; Ward, H.; Weiland, U.; Welling, H.; Williams, P.; Winkler, W.; Willke, B.; Zawischa, I.

    The GEO600 laser-interferometric gravitational wave detector near Hannover, Germany, is one of six such interferometers now close to operation worldwide. The UK/German GEO collaboration uses advanced technologies, including monolithic silica suspensions and signal recycling, to deliver a sensitivity comparable with much larger detectors in their initial configurations. Here we review the design and performance of GEO600 and consider the prospects for a direct detection of continuous gravitational waves from spinning neutron stars.

  18. Multiple detectors "Influence Method".

    PubMed

    Rios, I J; Mayer, R E

    2016-05-01

    The "Influence Method" is conceived for the absolute determination of a nuclear particle flux in the absence of known detector efficiency and without the need to register coincidences of any kind. This method exploits the influence of the presence of one detector in the count rate of another detector, when they are placed one behind the other and define statistical estimators for the absolute number of incident particles and for the efficiency (Rios and Mayer, 2015a). Its detailed mathematical description was recently published (Rios and Mayer, 2015b) and its practical implementation in the measurement of a moderated neutron flux arising from an isotopic neutron source was exemplified in (Rios and Mayer, 2016). With the objective of further reducing the measurement uncertainties, in this article we extend the method for the case of multiple detectors placed one behind the other. The new estimators for the number of particles and the detection efficiency are herein derived. PMID:26943904

  19. Subspace Detectors: Theory

    SciTech Connect

    Harris, D B

    2006-07-11

    Broadband subspace detectors are introduced for seismological applications that require the detection of repetitive sources that produce similar, yet significantly variable seismic signals. Like correlation detectors, of which they are a generalization, subspace detectors often permit remarkably sensitive detection of small events. The subspace detector derives its name from the fact that it projects a sliding window of data drawn from a continuous stream onto a vector signal subspace spanning the collection of signals expected to be generated by a particular source. Empirical procedures are presented for designing subspaces from clusters of events characterizing a source. Furthermore, a solution is presented for the problem of selecting the dimension of the subspace to maximize the probability of detecting repetitive events at a fixed false alarm rate. An example illustrates subspace design and detection using events in the 2002 San Ramon, California earthquake swarm.

  20. Inverter ratio failure detector

    NASA Technical Reports Server (NTRS)

    Wagner, A. P.; Ebersole, T. J.; Andrews, R. E. (Inventor)

    1974-01-01

    A failure detector which detects the failure of a dc to ac inverter is disclosed. The inverter under failureless conditions is characterized by a known linear relationship of its input and output voltages and by a known linear relationship of its input and output currents. The detector includes circuitry which is responsive to the detector's input and output voltages and which provides a failure-indicating signal only when the monitored output voltage is less by a selected factor, than the expected output voltage for the monitored input voltage, based on the known voltages' relationship. Similarly, the detector includes circuitry which is responsive to the input and output currents and provides a failure-indicating signal only when the input current exceeds by a selected factor the expected input current for the monitored output current based on the known currents' relationship.

  1. Microwave Radiation Detector

    NASA Technical Reports Server (NTRS)

    Lesh, J. R.

    1984-01-01

    Direct photon detector responds to microwave frequencies. Method based on trapped-ion frequency-generation standards proposed to detect radio-frequency (RF) radiation at 40.5 GHz. Technique used for directdetection (RF) communication, radar, and radio astronomy.

  2. The CBM RICH detector

    NASA Astrophysics Data System (ADS)

    Adamczewski-Musch, J.; Akishin, P.; Becker, K.-H.; Belogurov, S.; Bendarouach, J.; Boldyreva, N.; Chernogorov, A.; Deveaux, C.; Dobyrn, V.; Dürr, M.; Eschke, J.; Förtsch, J.; Heep, J.; Höohne, C.; Kampert, K.-H.; Kochenda, L.; Kopfer, J.; Kravtsov, P.; Kres, I.; Lebedev, S.; Lebedeva, E.; Leonova, E.; Linev, S.; Mahmoud, T.; Michel, J.; Miftakhov, N.; Niebur, W.; Ovcharenko, E.; Pauly, C.; Pfeifer, D.; Querchfeld, S.; Rautenberg, J.; Reinecke, S.; Riabov, Y.; Roshchin, E.; Samsonov, V.; Tarasenkova, O.; Traxler, M.; Ugur, C.; Vznuzdaev, E.; Vznuzdaev, M.

    2016-05-01

    The CBM RICH detector will use CO2 as radiator gas, focussing glass mirrors with Al+MgF2 reflective and protective coating and Hamamatsu H12700 MAPMTs as photon detectors. The detector will serve for electron to pion separation up to momenta of 8 GeV/c and thus enable in CBM the measurement of electromagnetic radiation from the early and dense fireball in A+A collisions at SIS 100. In this article, the current status of the CBM RICH development will be presented including new measurements of the radiation hardness of the H12700 MAPMT and WLS coatings with p-terphenyl, the new concept for the readout electronics, and optimizations ongoing with respect to the mirror mount structure and overall geometry. Prior to the usage in CBM, part of the already ordered MAPMTs will be used to upgrade the HADES RICH detector for a new measurement campaign at SIS 18 from 2018-2020.

  3. Simplified phase detector

    NASA Technical Reports Server (NTRS)

    Hershey, L. M.

    1979-01-01

    Tanlick sine-wave phase detector gives dc output voltage nearly proportional to phase difference between oscillator signal and reference signal. Device may be used for systems in which signal-to-noise ratio is high.

  4. Ultrafast neutron detector

    DOEpatents

    Wang, C.L.

    1985-06-19

    A neutron detector of very high temporal resolution is described. It may be used to measure distributions of neutrons produced by fusion reactions that persist for times as short as about 50 picoseconds.

  5. SRAM Detector Calibration

    NASA Technical Reports Server (NTRS)

    Soli, G. A.; Blaes, B. R.; Beuhler, M. G.

    1994-01-01

    Custom proton sensitive SRAM chips are being flown on the BMDO Clementine missions and Space Technology Research Vehicle experiments. This paper describes the calibration procedure for the SRAM proton detectors and their response to the space environment.

  6. Pocked surface neutron detector

    DOEpatents

    McGregor, Douglas; Klann, Raymond

    2003-04-08

    The detection efficiency, or sensitivity, of a neutron detector material such as of Si, SiC, amorphous Si, GaAs, or diamond is substantially increased by forming one or more cavities, or holes, in its surface. A neutron reactive material such as of elemental, or any compound of, .sup.10 B, .sup.6 Li, .sup.6 LiF, U, or Gd is deposited on the surface of the detector material so as to be disposed within the cavities therein. The portions of the neutron reactive material extending into the detector material substantially increase the probability of an energetic neutron reaction product in the form of a charged particle being directed into and detected by the neutron detector material.

  7. Pendulum detector testing device

    DOEpatents

    Gonsalves, J.M.

    1997-09-30

    A detector testing device is described which provides consistent, cost-effective, repeatable results. The testing device is primarily constructed of PVC plastic and other non-metallic materials. Sensitivity of a walk-through detector system can be checked by: (1) providing a standard test object simulating the mass, size and material content of a weapon or other contraband, (2) suspending the test object in successive positions, such as head, waist and ankle levels, simulating where the contraband might be concealed on a person walking through the detector system; and (3) swinging the suspended object through each of the positions, while operating the detector system and observing its response. The test object is retained in a holder in which the orientation of the test device or target can be readily changed, to properly complete the testing requirements. 5 figs.

  8. Pendulum detector testing device

    DOEpatents

    Gonsalves, John M.

    1997-01-01

    A detector testing device which provides consistent, cost-effective, repeatable results. The testing device is primarily constructed of PVC plastic and other non-metallic materials. Sensitivity of a walk-through detector system can be checked by: 1) providing a standard test object simulating the mass, size and material content of a weapon or other contraband, 2) suspending the test object in successive positions, such as head, waist and ankle levels, simulating where the contraband might be concealed on a person walking through the detector system; and 3) swinging the suspended object through each of the positions, while operating the detector system and observing its response. The test object is retained in a holder in which the orientation of the test device or target can be readily changed, to properly complete the testing requirements.

  9. Detector array design

    SciTech Connect

    Lari, S.

    1996-02-01

    Neutron scattering facility at Oak-Ridge National is used to measure residual stresses in many different materials. Neutron beam from the reactor can be used to penetrate the inner atomic distances of metals which then can be diffracted to a detector to measure the strain. The strain data later can be converted to stresses. The facility currently uses only one detector to carry the measurement. By designing an array of detectors data can be obtained at a much faster rate and or having a much better and improved resolution. The purpose of this report is to show design of such array of detectors and their movements (rotation) for possible maximum data collection at a faster rate.

  10. Modular optical detector system

    DOEpatents

    Horn, Brent A.; Renzi, Ronald F.

    2006-02-14

    A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the emitted fluorescence. Because the system is capable of accurately detecting and measuring picomolar concentrations it is ideally suited for use with microchemical analysis systems generally and capillary chromatographic systems in particular. By employing a modular design, the detector system provides both the ability to replace various elements of the detector system without requiring extensive realignment or recalibration of the components as well as minimal user interaction with the system. In addition, the modular concept provides for the use and addition of a wide variety of components, including optical elements (lenses and filters), light sources, and detection means, to fit particular needs.

  11. ISABELLE. Volume 3. Experimental areas, large detectors

    SciTech Connect

    Not Available

    1981-01-01

    This section presents the papers which resulted from work in the Experimental Areas portion of the Workshop. The immediate task of the group was to address three topics. The topics were dictated by the present state of ISABELLE experimental areas construction, the possibility of a phased ISABELLE and trends in physics and detectors.

  12. MONDE: MOmentum Neutron DEtector

    NASA Astrophysics Data System (ADS)

    Santa Rita, P.; Acosta, L.; Favela, F.; Huerta, A.; Ortiz, M. E.; Policroniades, R.; Chávez, E.

    2016-07-01

    MONDE is a large area neutron momentum detector, consisting of a 70x160x5 cm3 plastic scintillator slab surrounded by 16 photomultiplier tubes, standard NIM signal processing electronics and a CAMAC data acquisition system. In this work we present data from a characterization run using an external trigger. For that purpose, coincident gamma rays from a 60Co radioactive source were used together with a NaI external detector. First results with an "external" trigger are presented.

  13. Improved gaseous leak detector

    DOEpatents

    Juravic, F.E. Jr.

    1983-10-06

    In a short path length mass-spectrometer type of helium leak detector wherein the helium trace gas is ionized, accelerated and deflected onto a particle counter, an arrangement is provided for converting the detector to neon leak detection. The magnetic field of the deflection system is lowered so as to bring the nonlinear fringe area of the magnetic field across the ion path, thereby increasing the amount of deflection of the heavier neon ions.

  14. Gaseous leak detector

    DOEpatents

    Juravic, Jr., Frank E.

    1988-01-01

    In a short path length mass-spectrometer type of helium leak detector wherein the helium trace gas is ionized, accelerated and deflected onto a particle counter, an arrangement is provided for converting the detector to neon leak detection. The magnetic field of the deflection system is lowered so as to bring the non linear fringe area of the magnetic field across the ion path, thereby increasing the amount of deflection of the heavier neon ions.

  15. Compact infrared detector

    NASA Technical Reports Server (NTRS)

    Gupta, A.; Hong, S.; Moacanin, J.

    1981-01-01

    Broadband IR detector integrated into compact package for pollution monitoring and weather prediction is small, highly responsive, and immune to high noise. Sensing material is transparent sheet metalized with reflecting coating and overcoated with black material on same side. Pulse produced by chopping of infrared source beam creates transient "thermal lens" that temporarily defocuses laser beam probe. Detector monitoring beam measures defocusing which parallels infrared intensity.

  16. Fiber optic detector

    NASA Astrophysics Data System (ADS)

    Partin, Judy K.; Ward, Thomas E.; Grey, Alan E.

    1990-04-01

    This invention is comprised of a portable fiber optic detector that senses the presence of specific target chemicals by exchanging the target chemical for a fluorescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

  17. Fiber optic detector

    SciTech Connect

    Partin, J.K.; Ward, T.E.; Grey, A.E.

    1990-12-31

    This invention is comprised of a portable fiber optic detector that senses the presence of specific target chemicals by exchanging the target chemical for a fluorescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

  18. Group Counseling

    ERIC Educational Resources Information Center

    Mahler, Clarence A.

    1971-01-01

    This article reviews the major concerns of group counseling and differentiates among group guidance, group counseling, and group therapy. It also evaluates the research status of group counseling and presents implications for the future of this approach. Comment by Carl E. Thoresen follows. (Author)

  19. Thoughts on VCD-145 Detector Calibration

    SciTech Connect

    Morgan, W V

    2005-02-10

    In 1980, Don Smith requested that the EG&G Detector Group in North Las Vegas provide a summary of calibrated sensitivities for the VCD-145 detector. The &sired information was provided in a memorandum from Sam Egdorf (Reference 1). A memo from Brent Davis issued a week later described the effect on VCD-145 detector sensitivity that resulted from changing the thickness of the stainless steel entrance window (Reference 2). This memo is intended first to effectively archive those two references, and second to record thoughts about the significance of their contents. Reference 1 lists a total of 118 calibrated values for 80 different VCD-145 detectors, from 1977 to 1980. With only four exceptions, all of the serial numbers from V004 to V087 were included. The earlier calibrations were for detectors with 1-mil entrance windows, and the later ones were for detectors with 2-mil entrance windows. Three of the earlier units were calibrated at both thicknesses by temporarily placing an extra 1-mil sheet of stainless steel across the window. Altogether six different collimator diameters were used, from 60 mm to 95 mm. Some units were calibrated for more than one collimator diameter, and 14 were at some point designated as backup detectors for a second event. Reference 2 describes the effect of window thickness on calibrated sensitivity. Quoting that reference: ''To demonstrate that the sensitivity decrease is solely a function of the window thickness, a standard VCD-145 detector with a 0.001-inch thick window was calibrated with the {sup 60}Co source. Then without changing detector or geometry, a 0.001 -inch thick stainless steel foil (same material as that of the window) was placed directly in front of the detector window, effectively making a 0.002-inch thick entrance window. The detector was again calibrated. This technique was repeated until the detector had an entrance window equivalent to 0.010-inches thick.'' There are multiple reasons to suspect that the accuracy of

  20. Advanced Raman water vapor lidar

    NASA Technical Reports Server (NTRS)

    Whiteman, David N.; Melfi, S. Harvey; Ferrare, Richard A.; Evans, Keith A.; Ramos-Izquierdo, Luis; Staley, O. Glenn; Disilvestre, Raymond W.; Gorin, Inna; Kirks, Kenneth R.; Mamakos, William A.

    1992-01-01

    Water vapor and aerosols are important atmospheric constituents. Knowledge of the structure of water vapor is important in understanding convective development, atmospheric stability, the interaction of the atmosphere with the surface, and energy feedback mechanisms and how they relate to global warming calculations. The Raman Lidar group at the NASA Goddard Space Flight Center (GSFC) developed an advanced Raman Lidar for use in measuring water vapor and aerosols in the earth's atmosphere. Drawing on the experience gained through the development and use of our previous Nd:YAG based system, we have developed a completely new lidar system which uses a XeF excimer laser and a large scanning mirror. The additional power of the excimer and the considerably improved optical throughput of the system have resulted in approximately a factor of 25 improvement in system performance for nighttime measurements. Every component of the current system has new design concepts incorporated. The lidar system consists of two mobile trailers; the first (13m x 2.4m) houses the lidar instrument, the other (9.75m x 2.4m) is for system control, realtime data display, and analysis. The laser transmitter is a Lambda Physik LPX 240 iCC operating at 400 Hz with a XeF gas mixture (351 nm). The telescope is a .75m horizontally mounted Dall-Kirkham system which is bore sited with a .8m x 1.1m elliptical flat which has a full 180 degree scan capability - horizon to horizon within a plane perpendicular to the long axis of the trailer. The telescope and scan mirror assembly are mounted on a 3.65m x .9m optical table which deploys out the rear of the trailer through the use of a motor driven slide rail system. The Raman returns from water vapor (403 nm), nitrogen (383 nm) and oxygen (372 nm) are measured in addition to the direct Rayleigh/Mie backscatter (351). The signal from each of these is split at about a 5/95 ratio between two photomultiplier detectors. The 5 percent detector is used for

  1. Charge Detector for the Imaging Calorimeter for ACCESS (ICA)

    NASA Technical Reports Server (NTRS)

    Lee, Jeongin; Adams, J. H., Jr.

    2000-01-01

    NASA's Advanced Cosmic Ray Experiment for the Space Station (ACCESS) Mission is planned to consist of a transition radiation detector (TRD) and a thin ionization calorimeter. In order to measure the charge of the primary cosmic ray, it is necessary for the calorimeter to have its own charge detector. Silicon detectors are chosen for the charge detector because of their excellent resolution, small size and nearly square shape. Monte Carlo simulations are performed to find the probability of misidentifying protons as alpha particles due to backscattered radiation from the calorimeter. Simulations were also used to investigate identifying primary cosmic rays that fragmented in the TRD before reaching the calorimeter. For this study algorithms have been developed for determining a direction of the core shower in the calorimeter. These algorithms are used to find the approximate location of the primary particle in the silicon detectors. Results show the probability to misidentify the charge depends upon the energy and direction of the primary particles.

  2. Radiotherapy Does Not Influence the Severe Pulmonary Toxicity Observed With the Administration of Gemcitabine and Bleomycin in Patients With Advanced-Stage Hodgkin's Lymphoma Treated With the BAGCOPP Regimen: A Report by the German Hodgkin's Lymphoma Study Group

    SciTech Connect

    Macann, Andrew; Bredenfeld, Henning; Mueller, Rolf-Peter; Diehl, Volker; Engert, Andreas; Eich, Hans Theodor

    2008-01-01

    Purpose: To evaluate the effect of radiotherapy on the severe pulmonary toxicity observed in the pilot study of BAGCOPP (bleomycin, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone, and gemcitabine) for advanced-stage Hodgkin's lymphoma. Methods and Materials: Patients with Stage III or IV Hodgkin's lymphoma or Stage IIB with risk factors participated in this single-arm, multicenter pilot study. Results: Twenty-seven patients were enrolled on the study before its premature closure as a result of the development of serious pulmonary toxicity in 8 patients. The pulmonary toxicity occurred either during or immediately after the BAGCOPP chemotherapy course. Pulmonary toxicity contributed to one early fatality but resolved in the other 7 patients after cessation of gemcitabine and bleomycin, allowing continuation of therapy. Fifteen patients received consolidative radiotherapy, including 4 who previously had pulmonary toxicity. There were no reported cases of radiation pneumonitis and no exacerbation of pulmonary symptoms in the 4 patients who had had previous pulmonary toxicity. Conclusions: The severe pulmonary toxicity observed in this study has been attributed to an interaction between gemcitabine and bleomycin. Gemcitabine (when administered without bleomycin) remains of interest in Hodgkin's lymphoma and is being incorporated into a new German Hodgkin's Lymphoma Study Group protocol that also includes consolidative radiotherapy. This study supports the concept of the integration of radiotherapy in gemcitabine-containing regimens in Hodgkin's lymphoma if there is an interval of at least 4 weeks between the two modalities and with a schedule whereby radiotherapy follows the chemotherapy.

  3. Alkali metal ionization detector

    DOEpatents

    Bauerle, James E.; Reed, William H.; Berkey, Edgar

    1978-01-01

    Variations in the conventional filament and collector electrodes of an alkali metal ionization detector, including the substitution of helical electrode configurations for either the conventional wire filament or flat plate collector; or, the substitution of a plurality of discrete filament electrodes providing an in situ capability for transferring from an operationally defective filament electrode to a previously unused filament electrode without removing the alkali metal ionization detector from the monitored environment. In particular, the helical collector arrangement which is coaxially disposed about the filament electrode, i.e. the thermal ionizer, provides an improved collection of positive ions developed by the filament electrode. The helical filament design, on the other hand, provides the advantage of an increased surface area for ionization of alkali metal-bearing species in a monitored gas environment as well as providing a relatively strong electric field for collecting the ions at the collector electrode about which the helical filament electrode is coaxially positioned. Alternatively, both the filament and collector electrodes can be helical. Furthermore, the operation of the conventional alkali metal ionization detector as a leak detector can be simplified as to cost and complexity, by operating the detector at a reduced collector potential while maintaining the sensitivity of the alkali metal ionization detector adequate for the relatively low concentration of alkali vapor and aerosol typically encountered in leak detection applications.

  4. Gamma ray detector modules

    NASA Technical Reports Server (NTRS)

    Capote, M. Albert (Inventor); Lenos, Howard A. (Inventor)

    2009-01-01

    A radiation detector assembly has a semiconductor detector array substrate of CdZnTe or CdTe, having a plurality of detector cell pads on a first surface thereof, the pads having a contact metallization and a solder barrier metallization. An interposer card has planar dimensions no larger than planar dimensions of the semiconductor detector array substrate, a plurality of interconnect pads on a first surface thereof, at least one readout semiconductor chip and at least one connector on a second surface thereof, each having planar dimensions no larger than the planar dimensions of the interposer card. Solder columns extend from contacts on the interposer first surface to the plurality of pads on the semiconductor detector array substrate first surface, the solder columns having at least one solder having a melting point or liquidus less than 120 degrees C. An encapsulant is disposed between the interposer circuit card first surface and the semiconductor detector array substrate first surface, encapsulating the solder columns, the encapsulant curing at a temperature no greater than 120 degrees C.

  5. The on-orbit performance of the STIS detectors

    NASA Technical Reports Server (NTRS)

    Kimble, Randy A.

    1997-01-01

    The Space Telescope Imaging Spectrograph (STIS), successfully installed into the Hubble Space Telescope in February 1997, achieves its advances over the first-generation HST spectrographs primarily through the use of modern large-format, two-dimensional array detectors. The performance of the STIS detectors, two Multi-Anode Microchannel Arrays (MAMAS) and one CCD, has been evaluated on-orbit as part of the Servicing Mission Orbital Verification (SMOV) program. All three detectors are functioning well. We report highlights of the results to date here.

  6. The Next Generation of Ground-based Gravitational Wave Detectors

    NASA Astrophysics Data System (ADS)

    Losurdo, Giovanni; LIGO Scientific Collaboration; Virgo Collaboration

    2007-12-01

    LIGO, Virgo and GEO600, the first generation long-baseline interferometric detectors of gravitational waves, were taking data up until last fall. The analysis of the data collected is in progress and the first detection might be possible with these instruments. But, more sensitive detectors will be needed to start the field of gravitational wave astronomy. Advanced interferometers will improve the sensitivity by a factor of ten, thus enabling the exploration of a universe volume that is 1000 times larger than the present. The technology is almost ready and the construction of Advanced LIGO and Advanced Virgo is planned to start at the beginning of the next decade. With an expected event rate of 1/week-1/day these detectors will be powerful instruments that will provide a new way of observing the universe. As an intermediate step, in 2008 LIGO and Virgo will start the upgrade of the current detectors, working towards Enhanced LIGO and Virgo+. GEO600 has also planned a set of incremental upgrades (GEO HF) in order to enhance sensitivity in the high frequency range. In this talk the path towards the advanced detectors will be reviewed and the perspectives of the so-called 2nd generation long-baseline interferometers will be outlined.

  7. Major detectors in elementary-particle physics. [Portfolio

    SciTech Connect

    Gidal, G.; Armstrong, B.; Rittenberg, A.

    1983-03-01

    With the 1983 issue of LBL-91 we introduce a supplement - a folio of descriptions of the world's major elementary particle physics detectors. Modern high energy physics usually involves the use of massive, costly, carefully engineered, large solid angle detectors. These detectors require a long lead time for construction, are often integrated with an accelerator, accumulate data over many years, and are in reality a combination of numerous subsystems. As was the case with bubble chambers, many experiments are performed with the same data, or with data taken after relatively minor changes or additions to the detector configuration. These experiments are often reported in journals whose space limitations make repeated full descriptions of the detector impossible. The detailed properties and performance of the detector are usually described in a fragmented series of papers in more specialized, technologically oriented journals. New additions are often not well documented. Several detectors often make similar measurements and physicists want to make quick comparisons of their respective capabilities. Designers of new large detectors and even of smaller experiments need to know what already exists and what performance has been achieved. To aid the physics community, the Particle Data Group has produced this brief folio of the world's major large detectors. This first edition has some notable omissions: in particular, the bubble chambers and any associated spectrometers, and the still somewhat tentative LEP, SLC, and TRISTAN detectors.

  8. Development and preliminary tests of resistive microdot and microstrip detectors

    NASA Astrophysics Data System (ADS)

    Fonte, P.; Nappi, E.; Martinengo, P.; Oliveira, R.; Peskov, V.; Pietropaolo, F.; Picchi, P.

    2012-12-01

    In the last few years our group has focused on developing various designs of spark-protected micropattern gaseous detectors featuring resistive electrodes instead of traditional metallic ones: resistive microstrip counters, resistive gas electron multiplier, resistive micro mesh gaseous structure. These detectors combine in one design the best features of resistive plate chamber (spark-protection) and micropattern detectors (a high position resolution). In this paper we report the progress so far made in developing other types of resistive micropattern detectors: a microdot-microhole detector and a microgap-microstrip detector. The former detector is an optimal electron amplifier for some special designs of dual phase noble liquid time projection chambers, for example with a CsI photocathode immersed inside the noble liquid. Preliminary tests of such a detector, for the first time built and investigated, are reported in this paper. The latter detector is mainly orientated towards medical imaging applications such as x-ray scanners. However, we believe that after a proper gas optimization, these detectors could also achieve a high time resolution and could thus be used in applications as time of flight positron emission tomography, detection of charged particles with simultaneously high time and position resolution etc.

  9. Working Group C Summary

    NASA Astrophysics Data System (ADS)

    Nuhn, H.-D.

    2003-12-01

    Working group C, "Application to FELs," of the Joint ICFA Advanced Accelerator and Beam Dynamics Workshop on July 1-6, 2002 in Chia Laguna, Sardinia, Italy addressed a total of nine topics. This summary will discuss the topics that were addressed in the stand-alone sessions, including Start-To-End Simulations, SASE Experiment, PERSEO, "Optics Free" FEL Oscillators, and VISA II.

  10. The CLIC Vertex Detector

    NASA Astrophysics Data System (ADS)

    Dannheim, D.

    2015-03-01

    The precision physics needs at TeV-scale linear electron-positron colliders (ILC and CLIC) require a vertex-detector system with excellent flavour-tagging capabilities through a measurement of displaced vertices. This is essential, for example, for an explicit measurement of the Higgs decays to pairs of b-quarks, c-quarks and gluons. Efficient identification of top quarks in the decay t → Wb will give access to the ttH-coupling measurement. In addition to those requirements driven by physics arguments, the CLIC bunch structure calls for hit timing at the few-ns level. As a result, the CLIC vertex-detector system needs to have excellent spatial resolution, full geometrical coverage extending to low polar angles, extremely low material budget, low occupancy facilitated by time-tagging, and sufficient heat removal from sensors and readout. These considerations challenge current technological limits. A detector concept based on hybrid pixel-detector technology is under development for the CLIC vertex detector. It comprises fast, low-power and small-pitch readout ASICs implemented in 65 nm CMOS technology (CLICpix) coupled to ultra-thin planar or active HV-CMOS sensors via low-mass interconnects. The power dissipation of the readout chips is reduced by means of power pulsing, allowing for a cooling system based on forced gas flow. This contribution reviews the requirements and design optimisation for the CLIC vertex detector and gives an overview of recent R&D achievements in the domains of sensors, readout and detector integration.

  11. Development of a CMOS SOI Pixel Detector

    SciTech Connect

    Arai, Y.; Hazumi, M.; Ikegami, Y.; Kohriki, T.; Tajima, O.; Terada, S.; Tsuboyama, T.; Unno, Y.; Ushiroda, Y.; Ikeda, H.; Hara, K.; Ishino, H.; Kawasaki, T.; Miyake, H.; Martin, E.; Varner, G.; Tajima, H.; Ohno, M.; Fukuda, K.; Komatsubara, H.; Ida, J.; /NONE - OKI ELECTR INDUST TOKYO

    2008-08-19

    We have developed a monolithic radiation pixel detector using silicon on insulator (SOI) with a commercial 0.15 {micro}m fully-depleted-SOI technology and a Czochralski high resistivity silicon substrate in place of a handle wafer. The SOI TEG (Test Element Group) chips with a size of 2.5 x 2.5 mm{sup 2} consisting of 20 x 20 {micro}m{sup 2} pixels have been designed and manufactured. Performance tests with a laser light illumination and a {beta} ray radioactive source indicate successful operation of the detector. We also briefly discuss the back gate effect as well as the simulation study.

  12. Evaluation of commercial pyroelectric detectors

    NASA Technical Reports Server (NTRS)

    Robertson, J. B.; Crouch, R. K.

    1977-01-01

    A series of commercially available pyroelectric detectors made from PVF2, LTO, SBN, and TGS were evaluated in terms of responsivity and detectivity as a function of frequency. The performance of the detectors evaluated was very different, depending upon the manufacturer of the detector, and this dependency was primarily related to the thickness of the various detectors. The best detectors of each material were comparable in performance at frequencies around 10 Hz but differed radically at frequencies above 100 Hz.

  13. Advanced signal processing

    NASA Astrophysics Data System (ADS)

    Creasey, D. J.

    1985-12-01

    A collection of papers on advanced signal processing in radar, sonar, and communications is presented. The topics addressed include: transmitter aerials, high-power amplifier design for active sonar, radar transmitters, receiver array technology for sonar, new underwater acoustic detectors, diversity techniques in communications receivers, GaAs IC amplifiers for radar and communication receivers, integrated optical techniques for acoustooptic receivers, logarithmic receivers, CCD processors for sonar, acoustooptic correlators, designing in silicon, very high performance integrated circuits, and digital filters. Also discussed are: display types, scan converters in sonar, display ergonomics, simulators, high throughput sonar processors, optical fiber systems for signal processing, satellite communications, VLSI array processor for image and signal processing, ADA, future of cryogenic devices for signal processing applications, advanced image understanding, and VLSI architectures for real-time image processing.

  14. Independent testing of JWST detector prototypes

    NASA Astrophysics Data System (ADS)

    Figer, Donald F.; Rauscher, Bernard J.; Regan, Michael W.; Morse, Ernie; Balleza, Jesus; Bergeron, Louis; Stockman, H. S.

    2004-01-01

    The Independent Detector Testing Laboratory (IDTL) is jointly operated by the Space Telescope Science Institute (STScI) and the Johns Hopkins University (JHU), and is assisting the James Webb Space Telescope (JWST) mission in choosing and operating the best near-infrared detectors. The JWST is the centerpiece of the NASA Office of Space Science theme, the Astronomical Search for Origins, and the highest priority astronomy project for the next decade, according to the National Academy of Science. JWST will need to have the sensitivity to see the first light in the Universe to determine how galaxies formed in the web of dark matter that existed when the Universe was in its infancy (z~10-20). To achieve this goal, the JWST Project must pursue an aggressive technology program and advance infrared detectors to performance levels beyond what is now possible. As part of this program, NASA has selected the IDTL to verify comparative performance between prototype JWST detectors developed by Rockwell Scientific (HgCdTe) and Raytheon (InSb). The IDTL is charged with obtaining an independent assessment of the ability of these two competing technologies to achieve the demanding specifications of the JWST program within the 0.6-5 μm bandpass and in an ultra-low background (<0.01 e-/s/pixel) environment. We describe results from the JWST Detector Characterization Project that is being performed in the IDTL. In this project, we are measuring first-order detector parameters, i.e. dark current, read noise, QE, intra-pixel sensitivity, linearity, as functions of temperature, well size, and operational mode.

  15. Independent Testing of JWST Detector Prototypes

    NASA Technical Reports Server (NTRS)

    Figer, D. F.; Rauscher, B. J.; Regan, M. W.; Balleza, J.; Bergeron, L.; Morse, E.; Stockman, H. S.

    2003-01-01

    The Independent Detector Testing Laboratory (IDTL) is jointly operated by the Space Telescope Science Institute (STScI) and the Johns Hopkins University (MU), and is assisting the James Webb Space Telescope (JWST) mission in choosing and operating the best near-infrared detectors under a NASA Grant. The JWST is the centerpiece of the NASA Office of Space Science theme, the Astronomical Search for Origins, and the highest priority astronomy project for the next decade, according to the National Academy of Science. JWST will need to have the sensitivity to see the first light in the Universe to determine how galaxies formed in the web of dark matter that existed when the Universe was in its infancy (z approx. 10 - 20). To achieve this goal, the JWST Project must pursue an aggressive technology program and advance infrared detectors to performance levels beyond what is now possible. As part of this program, NASA has selected the IDTL to verify comparative performance between prototype JWST detectors developed by Rockwell Scientific (HgCdTe) and Raytheon (InSb). The IDTL is charged with obtaining an independent assessment of the ability of these two competing technologies to achieve the demanding specifications of the JWST program within the 0.6 - 5 approx. mum bandpass and in an ultra-low background (less than 0.01 e'/s/pixel) environment. We describe results from the JWST Detector Characterization Project that is being performed in the IDTL. In this project, we are measuring first-order detector parameters, i.e. dark current, read noise, QE, intra-pixel sensitivity, linearity, as functions of temperature, well size, and operational mode.

  16. Independent Testing of JWST Detector Prototypes

    NASA Technical Reports Server (NTRS)

    Figer, Donald F.; Rauscher, Bernie J.; Regan, Michael W.; Morse, Ernie; Balleza, Jesus; Bergeron, Louis; Stockman, H. S.

    2004-01-01

    The Independent Detector Testing Laboratory (IDTL) is jointly operated by the Space Telescope Science Institute (STScI) and the Johns Hopkins University (JHU), and is assisting the James Webb Space Telescope (JWST) mission in choosing and operating the best near-infrared detectors. The JWST is the centerpiece of the NASA Office of Space Science theme, the Astronomical Search for Origins, and the highest priority astronomy project for the next decade, according to the National Academy of Science. JWST will need to have the sensitivity to see the first light in the Universe to determine how galaxies formed in the web of dark matter that existed when the Universe was in its infancy (z is approximately 10-20). To achieve this goal, the JWST Project must pursue an aggressive technology program and advance infrared detectors to performance levels beyond what is now possible. As part of this program, NASA has selected the IDTL to verify comparative performance between prototype JWST detectors developed by Rockwell Scientific (HgCdTe) and Raytheon (InSb). The IDTL is charged with obtaining an independent assessment of the ability of these two competing technologies to achieve the demanding specifications of the JWST program within the 0.6-5 micron bandpass and in an ultra-low background (less than 0.01 e(-)/s/pixel) environment. We describe results from the JWST Detector Characterization Project that is being performed in the LDTL. In this project, we are measuring first-order detector parameters, i.e. dark current, read noise, QE, intra-pixel sensitivity, linearity, as functions of temperature, well size, and operational mode.

  17. Cisplatin plus oral etoposide (EoP) combination is more effective than paclitaxel in patients with advanced breast cancer pretreated with anthracyclines: a randomised phase III trial of Turkish Oncology Group

    PubMed Central

    Icli, F; Akbulut, H; Uner, A; Yalcin, B; Baltali, E; Altinbas, M; Coşkun, Ş; Komurcu, S; Erkisi, M; Demirkazik, A; Senler, F C; Sencan, O; Büyükcelik, A; Boruban, C; Onur, H; Zengin, N; Sak, S D

    2005-01-01

    Our objective was to determine whether oral etoposide and cisplatin combination (EoP) is superior to paclitaxel in the treatment of advanced breast cancer (ABC) patients pretreated with anthracyclines. From December 1997 to August 2003, 201 patients were randomised, 100 to EoP and 101 to paclitaxel arms. Four patients in each arm were ineligible. The doses of etoposide and cisplatin were 50 mg p.o. twice a day for 7 days and 70 mg m−2 intravenously (i.v.) on day 1, respectively, and it was 175 mg m−2 on day 1 for paclitaxel. Both treatments were repeated every 3 weeks. A median of four cycles of study treatment was given in both arms. The response rate obtained in the EoP arm was significantly higher (36.3 vs 22.2%; P=0.038). Median response duration was longer for the EoP arm (7 vs 4 months) (P=0.132). Also, time to progression was significantly in favour of the EoP arm (5.5 vs 3.9 months; P=0.003). Median overall survival was again significantly longer in the EoP arm (14 vs 9.5 months; P=0.039). Toxicity profile of both groups was similar. Two patients in each arm were lost due to febrile neutropenia. The observed activity and acceptable toxicity of EoP endorses the employment of this combination in the treatment of ABC following anthracyclines. PMID:15726120

  18. Randomized Phase II Study of Pemetrexed, Carboplatin, and Thoracic Radiation With or Without Cetuximab in Patients With Locally Advanced Unresectable Non–Small-Cell Lung Cancer: Cancer and Leukemia Group B Trial 30407

    PubMed Central

    Govindan, Ramaswamy; Bogart, Jeffrey; Stinchcombe, Thomas; Wang, Xiaofei; Hodgson, Lydia; Kratzke, Robert; Garst, Jennifer; Brotherton, Timothy; Vokes, Everett E.

    2011-01-01

    Purpose Cancer and Leukemia Group B conducted a randomized phase II trial to investigate two novel chemotherapy regimens in combination with concurrent thoracic radiation therapy (TRT). Patients and Methods Patients with unresectable stage III non–small-cell lung cancer (NSCLC) were randomly assigned to carboplatin (area under the curve, 5) and pemetrexed (500 mg/m2) every 21 days for four cycles and TRT (70 Gy; arm A) or the same treatment with cetuximab administered concurrent only with TRT (arm B). Patients in both arms received up to four cycles of pemetrexed as consolidation therapy. The primary end point was the 18-month overall survival (OS) rate; if the 18-month OS rate was ≥ 55%, the regimen(s) would be considered for further study. Results Of the 101 eligible patients enrolled (48 in arm A and 53 in arm B), 60% were male; the median age was 66 years (range, 32 to 81 years); 44% and 35% had adenocarcinoma and squamous carcinoma, respectively; and more patients enrolled onto arm A compared with arm B had a performance status of 0 (58% v 34%, respectively; P = .04). The 18-month OS rate was 58% (95% CI, 46% to 74%) in arm A and 54% (95% CI, 42% to 70%) in arm B. No significant difference in OS between patients with squamous and nonsquamous NSCLC was observed (P = .667). The toxicities observed were consistent with toxicities associated with concurrent chemoradiotherapy. Conclusion The combination of pemetrexed, carboplatin, and TRT met the prespecified criteria for further evaluation. This regimen should be studied further in patients with locally advanced unresectable nonsquamous NSCLC. PMID:21747084

  19. Astrophysical calibration of gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Pitkin, M.; Messenger, C.; Wright, L.

    2016-03-01

    We investigate a method to assess the validity of gravitational-wave detector calibration through the use of gamma-ray bursts as standard sirens. Such signals, as measured via gravitational-wave observations, provide an estimated luminosity distance that is subject to uncertainties in the calibration of the data. If a host galaxy is identified for a given source then its redshift can be combined with current knowledge of the cosmological parameters yielding the true luminosity distance. This will then allow a direct comparison with the estimated value and can validate the accuracy of the original calibration. We use simulations of individual detectable gravitational-wave signals from binary neutron star (BNS) or neutron star-black hole systems, which we assume to be found in coincidence with short gamma-ray bursts, to estimate any discrepancy in the overall scaling of the calibration for detectors in the Advanced LIGO and Advanced Virgo network. We find that the amplitude scaling of the calibration for the LIGO instruments could on average be confirmed to within ˜10 % for a BNS source within 100 Mpc. This result is largely independent of the current detector calibration method and gives an uncertainty that is competitive with that expected in the current calibration procedure. Confirmation of the calibration accuracy to within ˜20 % can be found with BNS sources out to ˜500 Mpc .

  20. Handheld CZT radiation detector

    SciTech Connect

    Murray, William S.; Butterfield, Kenneth B.; Baird, William

    2004-08-24

    A handheld CZT radiation detector having a CZT gamma-ray sensor, a multichannel analyzer, a fuzzy-logic component, and a display component is disclosed. The CZT gamma-ray sensor may be a coplanar grid CZT gamma-ray sensor, which provides high-quality gamma-ray analysis at a wide range of operating temperatures. The multichannel analyzer categorizes pulses produce by the CZT gamma-ray sensor into channels (discrete energy levels), resulting in pulse height data. The fuzzy-logic component analyzes the pulse height data and produces a ranked listing of radioisotopes. The fuzzy-logic component is flexible and well-suited to in-field analysis of radioisotopes. The display component may be a personal data assistant, which provides a user-friendly method of interacting with the detector. In addition, the radiation detector may be equipped with a neutron sensor to provide an enhanced mechanism of sensing radioactive materials.

  1. Semiconductor radiation detector

    DOEpatents

    Patt, Bradley E.; Iwanczyk, Jan S.; Tull, Carolyn R.; Vilkelis, Gintas

    2002-01-01

    A semiconductor radiation detector is provided to detect x-ray and light photons. The entrance electrode is segmented by using variable doping concentrations. Further, the entrance electrode is physically segmented by inserting n+ regions between p+ regions. The p+ regions and the n+ regions are individually biased. The detector elements can be used in an array, and the p+ regions and the n+ regions can be biased by applying potential at a single point. The back side of the semiconductor radiation detector has an n+ anode for collecting created charges and a number of p+ cathodes. Biased n+ inserts can be placed between the p+ cathodes, and an internal resistor divider can be used to bias the n+ inserts as well as the p+ cathodes. A polysilicon spiral guard can be implemented surrounding the active area of the entrance electrode or surrounding an array of entrance electrodes.

  2. Imaging MAMA detector systems

    NASA Astrophysics Data System (ADS)

    Slater, David C.; Timothy, J. G.; Morgan, Jeffrey S.; Kasle, David B.

    1990-07-01

    Imaging multianode microchannel array (MAMA) detector systems with 1024 x 1024 pixel formats have been produced for visible and UV wavelengths; the UV types employ 'solar blind' photocathodes whose detective quantum efficiencies are significantly higher than those of currently available CCDs operating at far-UV and EUV wavelengths. Attention is presently given to the configurations and performance capabilities of state-of-the-art MAMA detectors, with a view to the development requirements of the hybrid electronic circuits needed for forthcoming spacecraft-sensor applications. Gain, dark noise, uniformity, and dynamic range performance data are presented for the curved-channel 'chevron', 'Z-plate', and helical-channel high gain microchannel plate configurations that are currently under evaluation with MAMA detector systems.

  3. JSATS Detector Field Manual

    SciTech Connect

    Choi, Eric Y.; Flory, Adam E.; Lamarche, Brian L.; Weiland, Mark A.

    2014-06-01

    The Juvenile Salmon Acoustic Telemetry System (JSATS) Detector is a software and hardware system that captures JSATS Acoustic Micro Transmitter (AMT) signals. The system uses hydrophones to capture acoustic signals in the water. This analog signal is then amplified and processed by the Analog to Digital Converter (ADC) and Digital Signal Processor (DSP) board in the computer. This board digitizes and processes the acoustic signal to determine if a possible JSATS tag is present. With this detection, the data will be saved to the computer for further analysis. This document details the features and functionality of the JSATS Detector software. The document covers how to install the software, setup and run the detector software. The document will also go over the raw binary waveform file format and CSV files containing RMS values

  4. Trastuzumab Emtansine for Treating HER2-Positive, Unresectable, Locally Advanced or Metastatic Breast Cancer After Treatment with Trastuzumab and a Taxane: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

    PubMed

    Squires, Hazel; Stevenson, Matt; Simpson, Emma; Harvey, Rebecca; Stevens, John

    2016-07-01

    The National Institute for Health and Care Excellence (NICE) invited the manufacturer of trastuzumab emtansine (T-DM1) (Kadcyla(®); Roche) to submit evidence of its clinical and cost-effectiveness for treating human epidermal growth factor receptor 2 (HER2)-positive, unresectable, locally advanced or metastatic breast cancer after treatment with trastuzumab and a taxane. The School of Health and Related Research Technology Appraisal Group (ScHARR-TAG) at the University of Sheffield were the independent Evidence Review Group (ERG) who produced a critical review of the company's submission to NICE. The ERG also independently searched for relevant evidence and modified the submitted decision analytic model to produce a revised estimate of cost-effectiveness and examine the impact of altering some of the key assumptions. The clinical effectiveness data were taken from two randomised controlled trials that reported a significant advantage in progression-free survival (PFS) for T-DM1 over lapatinib in combination with capecitabine (EMILIA trial), and over the treatment of physician's choice (TH3RESA trial). A network meta-analysis suggested T-DM1 was the best treatment in terms of both overall survival and PFS compared with lapatinib in combination with capecitabine; trastuzumab in combination with capecitabine; and capecitabine monotherapy. Adverse event (AE) data were taken from a pooled analysis of additional trials of T-DM1 as a single agent. The most common grade 3 or greater AEs for T-DM1 were thrombocytopenia and hepatotoxicity. Following the clarification process, the manufacturer reported a deterministic incremental cost-effectiveness ratio (ICER) for T-DM1 compared with lapatinib in combination with capecitabine of £167,236, the latter of which was estimated to have an ICER of £49,798 compared with capecitabine monotherapy. The ERG produced similar values of £166,429 and £50,620 respectively. All other comparators were dominated. During the appraisal, the

  5. Group X

    SciTech Connect

    Fields, Susannah

    2007-08-16

    This project is currently under contract for research through the Department of Homeland Security until 2011. The group I was responsible for studying has to remain confidential so as not to affect the current project. All dates, reference links and authors, and other distinguishing characteristics of the original group have been removed from this report. All references to the name of this group or the individual splinter groups has been changed to 'Group X'. I have been collecting texts from a variety of sources intended for the use of recruiting and radicalizing members for Group X splinter groups for the purpose of researching the motivation and intent of leaders of those groups and their influence over the likelihood of group radicalization. This work included visiting many Group X websites to find information on splinter group leaders and finding their statements to new and old members. This proved difficult because the splinter groups of Group X are united in beliefs, but differ in public opinion. They are eager to tear each other down, prove their superiority, and yet remain anonymous. After a few weeks of intense searching, a list of eight recruiting texts and eight radicalizing texts from a variety of Group X leaders were compiled.

  6. Group Flow and Group Genius

    ERIC Educational Resources Information Center

    Sawyer, Keith

    2015-01-01

    Keith Sawyer views the spontaneous collaboration of group creativity and improvisation actions as "group flow," which organizations can use to function at optimum levels. Sawyer establishes ideal conditions for group flow: group goals, close listening, complete concentration, being in control, blending egos, equal participation, knowing…

  7. Fissile material detector

    DOEpatents

    Ivanov, Alexander I.; Lushchikov, Vladislav I.; Shabalin, Eugeny P.; Maznyy, Nikita G.; Khvastunov, Michael M.; Rowland, Mark

    2002-01-01

    A detector for fissile materials which provides for integrity monitoring of fissile materials and can be used for nondestructive assay to confirm the presence of a stable content of fissile material in items. The detector has a sample cavity large enough to enable assay of large items of arbitrary configuration, utilizes neutron sources fabricated in spatially extended shapes mounted on the endcaps of the sample cavity, incorporates a thermal neutron filter insert with reflector properties, and the electronics module includes a neutron multiplicity coincidence counter.

  8. Mossbauer spectrometer radiation detector

    NASA Technical Reports Server (NTRS)

    Singh, J. J. (Inventor)

    1973-01-01

    A Mossbauer spectrometer with high efficiencies in both transmission and backscattering techniques is described. The device contains a sodium iodide crystal for detecting radiation caused by the Mossbauer effect, and two photomultipliers to collect the radiation detected by the crystal. When used in the transmission technique, the sample or scatterer is placed between the incident radiation source and the detector. When used in a backscattering technique, the detector is placed between the incident radiation source and the sample of scatterer such that the incident radiation will pass through a hole in the crystal and strike the sample. Diagrams of the instrument are provided.

  9. Acoustic emission intrusion detector

    DOEpatents

    Carver, Donald W.; Whittaker, Jerry W.

    1980-01-01

    An intrusion detector is provided for detecting a forcible entry into a secured structure while minimizing false alarms. The detector uses a piezoelectric crystal transducer to sense acoustic emissions. The transducer output is amplified by a selectable gain amplifier to control the sensitivity. The rectified output of the amplifier is applied to a Schmitt trigger circuit having a preselected threshold level to provide amplitude discrimination. Timing circuitry is provided which is activated by successive pulses from the Schmitt trigger which lie within a selected time frame for frequency discrimination. Detected signals having proper amplitude and frequency trigger an alarm within the first complete cycle time of a detected acoustical disturbance signal.

  10. The KEDR detector

    NASA Astrophysics Data System (ADS)

    Anashin, V. V.; Aulchenko, V. M.; Baldin, E. M.; Barladyan, A. K.; Barnyakov, A. Yu.; Barnyakov, M. Yu.; Baru, S. E.; Basok, I. Yu.; Bedny, I. V.; Beloborodova, O. L.; Blinov, A. E.; Blinov, V. E.; Bobrov, A. V.; Bobrovnikov, V. S.; Bondar, A. E.; Buzykaev, A. R.; Vorobiov, A. I.; Gulevich, V. V.; Dneprovsky, L. V.; Zhilich, V. N.; Zhulanov, V. V.; Karpov, G. V.; Karpov, S. V.; Kononov, S. A.; Kotov, K. Yu.; Kravchenko, E. A.; Kudryavtsev, V. N.; Kuzmin, A. S.; Kulikov, V. F.; Kuper, E. A.; Levichev, E. B.; Maksimov, D. A.; Malyshev, V. M.; Maslennikov, A. L.; Medvedko, A. S.; Muchnoi, N. Yu.; Nikitin, S. A.; Nikolaev, I. B.; Onuchin, A. P.; Oreshkin, S. B.; Orlov, I. O.; Osipov, A. A.; Peleganchuk, S. V.; Pivovarov, S. G.; Poluektov, A. O.; Pospelov, G. E.; Prisekin, V. G.; Rodyakin, V. A.; Ruban, A. A.; Savinov, G. A.; Skovpen, Yu. I.; Skrinsky, A. N.; Smalyuk, V. V.; Snopkov, R. G.; Sokolov, A. V.; Sukharev, A. M.; Talyshev, A. A.; Tayursky, V. A.; Telnov, V. I.; Tikhonov, Yu. A.; Todyshev, K. Yu.; Usov, Yu. V.; Kharlamova, T. A.; Shamov, A. G.; Shwartz, B. A.; Shekhtman, L. I.; Shusharo, A. I.; Yushkov, A. N.

    2013-07-01

    The KEDR detector is a universal magnetic detector designed for studying the c- and b-quarks and two-photon physics, and is employed at the VEPP-4M e + e - collider. A specific feature of the experiment is the measurement of absolute beam energy using two methods: the resonant depolarization and the faster but less precise Compton backscattering of laser photons. This allowed a large series of measurements to be performed, in which the accuracy of determination of such fundamental parameters of particles as mass and total and leptonic widths was improved.

  11. Cosmic ray detectors

    NASA Technical Reports Server (NTRS)

    Gregory, John C.

    1987-01-01

    Work on the MSFC emulsion laboratory microscopes in which mechanical modifications previously made were verified is reviewed, as is a design study of a large area hybrid electronic/emulsion chamber balloon flight detector system. This design is built upon the experience obtained with the highly successful MSFC/UAH hybrid instrument flown by the JACEE consortium. The design included overall system design and specification, design and fabrication of a prototype large light diffusion for Cerenkov charge detector or scintillator, design of a multiwire proportional counter array and design of the gondola or flight support system.

  12. High efficiency photoionization detector

    DOEpatents

    Anderson, David F.

    1984-01-01

    A high efficiency photoionization detector using tetraaminoethylenes in a gaseous state having a low ionization potential and a relative photoionization cross section which closely matches the emission spectrum of xenon gas. Imaging proportional counters are also disclosed using the novel photoionization detector of the invention. The compound of greatest interest is TMAE which comprises tetrakis(dimethylamino)ethylene which has a measured ionization potential of 5.36.+-.0.02 eV, and a vapor pressure of 0.35 torr at 20.degree. C.

  13. RADIATION WAVE DETECTOR

    DOEpatents

    Wouters, L.F.

    1958-10-28

    The detection of the shape and amplitude of a radiation wave is discussed, particularly an apparatus for automatically indicating at spaced lntervals of time the radiation intensity at a flxed point as a measure of a radiation wave passing the point. The apparatus utilizes a number of photomultiplier tubes surrounding a scintillation type detector, For obtainlng time spaced signals proportional to radiation at predetermined intervals the photolnultiplier tubes are actuated ln sequence following detector incidence of a predetermined radiation level by electronic means. The time spaced signals so produced are then separately amplified and relayed to recording means.

  14. Dosimetry with diamond detectors

    NASA Astrophysics Data System (ADS)

    Gervino, G.; Marino, C.; Silvestri, F.; Lavagno, A.; Truc, F.

    2010-05-01

    In this paper we present the dosimetry analysis in terms of stability and repeatability of the signal and dose rate dependence of a synthetic single crystal diamond grown by Chemical Vapor Deposition (CVD) technique. The measurements carried out by 5 MeV X-ray photons beam show very promising results, even if the dose rate detector response points out that the charge trapping centers distribution is not uniform inside the crystal volume. This handicap that affects the detectors performances, must be ascribed to the growing process. Synthetic single crystal diamonds could be a valuable alternative to air ionization chambers for quality beam control and for intensity modulated radiation therapy beams dosimetry.

  15. Intelligent Detector Design

    SciTech Connect

    Graf, N.; Cassell, R.; Johnson, T.; McCormick, J.; Magill, S.; Kuhlmann, S.; /Argonne

    2007-02-13

    At a future e+e- linear collider, precision measurements of jets will be required in order to understand physics at and beyond the electroweak scale. Calorimetry will be used with other detectors in an optimal way to reconstruct particle 4-vectors with unprecedented precision. This Particle Flow Algorithm (PFA) approach is seen as the best way to achieve particle mass resolutions from dijet measurements in the range of {approx} 30%/{radical}E, resulting in innovative methods for choosing the calorimeter technology and optimizing the detector design.

  16. Future water Cherenkov detectors

    SciTech Connect

    Bergevin, Marc

    2015-05-15

    In these proceedings a review of the current proposed large-scale Warer Cherenkov experiments is given. An argument is made that future water Cherenkov detectors would benefit in the investment in neutron detection technology. A brief overview will be given of proposed water Cherenkov experiments such as HYPER-K and MEMPHYS and other R and D experiments to demonstrate neutron capture in water Cherenkov detectors. Finally, innovation developed in the context of the now defunct LBNE Water R and D option to improve Water Cherenkov technology will be described.

  17. High efficiency photoionization detector

    DOEpatents

    Anderson, D.F.

    1984-01-31

    A high efficiency photoionization detector is described using tetraaminoethylenes in a gaseous state having a low ionization potential and a relative photoionization cross section which closely matches the emission spectrum of xenon gas. Imaging proportional counters are also disclosed using the novel photoionization detector of the invention. The compound of greatest interest is TMAE which comprises tetrakis(dimethylamino)ethylene which has a measured ionization potential of 5.36 [+-] 0.02 eV, and a vapor pressure of 0.35 torr at 20 C. 6 figs.

  18. Ultrasonic liquid level detector

    DOEpatents

    Kotz, Dennis M.; Hinz, William R.

    2010-09-28

    An ultrasonic liquid level detector for use within a shielded container, the detector being tubular in shape with a chamber at its lower end into which liquid from in the container may enter and exit, the chamber having an ultrasonic transmitter and receiver in its top wall and a reflector plate or target as its bottom wall whereby when liquid fills the chamber a complete medium is then present through which an ultrasonic wave may be transmitted and reflected from the target thus signaling that the liquid is at chamber level.

  19. Radiation Detectors and Art

    NASA Astrophysics Data System (ADS)

    Denker, Andrea

    The use of radiation detectors in the analysis of art objects represents a very special application in a true interdisciplinary field. Radiation detectors employed in this field detect, e.g., x-rays, γ-rays, β particles, and protons. Analyzed materials range from stones, metals, over porcelain to paintings. The available nondestructive and noninvasive analytical methods cover a broad range of techniques. Hence, for the sake of brevity, this chapter will concentrate on few techniques: Proton Induced X-ray Emission (PIXE) and Proton Induced γ-ray Emission (PIGE).

  20. Calibration of the GLAST Burst Monitor detectors

    SciTech Connect

    Kienlin, Andreas von; Bissaldi, Elisabetta; Lichti, Giselher G.; Steinle, Helmut; Diehl, Roland; Greiner, Jochen; Krumrey, Michael; Gerlach, Martin; Fishman, Gerald J.; Meegan, Charles; Kouveliotou, Chryssa; Wilson-Hodge, Colleen; Bhat, Narayana; Briggs, Michael S.; Connaughton, Valerie; Paciesas, William; Preece, Robert; Kippen, R. Marc

    2007-07-12

    The GLAST Burst Monitor (GBM) will augment the capabilities of GLAST for the detection of cosmic gamma-ray bursts by extending the energy range (20 MeV to > 300 GeV) of the Large Area Telescope (LAT) towards lower energies by 2 BGO-detectors (150 keV to 30 MeV) and 12 NaI(Tl) detectors (10 keV to 1 MeV). The physical detector response of the GBM instrument for GRBs is determined with the help of Monte Carlo simulations, which are supported and verified by on-ground calibration measurements, performed extensively with the individual detectors at the MPE in 2005. All flight and spare detectors were irradiated with calibrated radioactive sources in the laboratory (from 14 keV to 4.43 MeV). The energy/channel-relations, the dependences of energy resolution and effective areas on the energy and the angular responses were measured. Due to the low number of emission lines of radioactive sources below 100 keV, calibration measurements in the energy range from 10 keV to 60 keV were performed with the X-ray radiometry working group of the Physikalisch-Technische Bundesanstalt (PTB) at the BESSY synchrotron radiation facility, Berlin.

  1. Calibration of the GLAST Burst Monitor Detectors

    SciTech Connect

    von Kienlin, Andreas; Bissaldi, Elisabetta; Lichti, Giselher G.; Steinle, Helmut; Krumrey, Michael; Gerlach, Martin; Fishman, Gerald J.; Meegan, Charles; Bhat, Narayana; Briggs, Michael S.; Diehl, Roland; Connaughton, Valerie; Greiner, Jochen; Kippen, R.Marc; Kouveliotou, Chryssa; Paciesas, William; Preece, Robert; Wilson-Hodge, Colleen

    2011-11-29

    The GLAST Burst Monitor (GBM) will augment the capabilities of GLAST for the detection of cosmic gamma-ray bursts by extending the energy range (20 MeV to > 300 GeV) of the Large Area Telescope (LAT) towards lower energies by 2 BGO-detectors (150 keV to 30 MeV) and 12 NaI(Tl) detectors (10 keV to 1 MeV). The physical detector response of the GBM instrument for GRBs is determined with the help of Monte Carlo simulations, which are supported and verified by on-ground calibration measurements, performed extensively with the individual detectors at the MPE in 2005. All flight and spare detectors were irradiated with calibrated radioactive sources in the laboratory (from 14 keV to 4.43 MeV). The energy/channel-relations, the dependences of energy resolution and effective areas on the energy and the angular responses were measured. Due to the low number of emission lines of radioactive sources below 100 keV, calibration measurements in the energy range from 10 keV to 60 keV were performed with the X-ray radiometry working group of the Physikalisch-Technische Bundesanstalt (PTB) at the BESSY synchrotron radiation facility, Berlin.

  2. Metabolomics and Epidemiology Working Group

    Cancer.gov

    The Metabolomics and Epidemiology (MetEpi) Working Group promotes metabolomics analyses in population-based studies, as well as advancement in the field of metabolomics for broader biomedical and public health research.

  3. The Upgraded D0 detector

    SciTech Connect

    Abazov, V.M.; Abbott, B.; Abolins, M.; Acharya, B.S.; Adams, D.L.; Adams, M.; Adams, T.; Agelou, M.; Agram, J.-L.; Ahmed, S.N.; Ahn, S.H.; Ahsan, M.; Alexeev, G.D.; Alkhazov, G.; Alton, A.; Alverson, G.; Alves, G.A.; Anastasoaie, M.; Andeen, T.; Anderson, J.T.; Anderson, S.; /Buenos Aires U. /Rio de Janeiro, CBPF /Sao Paulo, IFT /Alberta U. /Simon Fraser U. /York U., Canada /McGill U. /Beijing, Inst. High Energy Phys. /Hefei, CUST /Andes U., Bogota /Charles U. /Prague, Tech. U. /Prague, Inst. Phys. /San Francisco de Quito U. /Clermont-Ferrand U. /LPSC, Grenoble /Marseille, CPPM /Orsay, LAL /Paris U., VI-VII /DAPNIA, Saclay /Strasbourg, IReS

    2005-07-01

    The D0 experiment enjoyed a very successful data-collection run at the Fermilab Tevatron collider between 1992 and 1996. Since then, the detector has been upgraded to take advantage of improvements to the Tevatron and to enhance its physics capabilities. We describe the new elements of the detector, including the silicon microstrip tracker, central fiber tracker, solenoidal magnet, preshower detectors, forward muon detector, and forward proton detector. The uranium/liquid-argon calorimeters and central muon detector, remaining from Run I, are discussed briefly. We also present the associated electronics, triggering, and data acquisition systems, along with the design and implementation of software specific to D0.

  4. Isopermutation group

    SciTech Connect

    Muktibodh, A. S.

    2015-03-10

    The concept of ‘Isotopy’ as formulated by Ruggero Maria Santilli [1, 2, 3] plays a vital role in the development of Iso mathematics. Santilli defined iso-fields of characteristic zero. In this paper we extend this definition to define Iso-Galois fields [4] which are essentially of non-zero characteristic. Isotopically isomorphic realizations of a group define isopermutation group which gives a clear cut distinction between automorphic groups and isotopic groups.

  5. Separation Group.

    ERIC Educational Resources Information Center

    Addington, Jean

    1992-01-01

    Describes eight-week short-term group designed to help separated or divorced men and women move through related adjustment phase in focused group setting. Discusses constructs that form the foundations of this short-term psychoeducational and support group and presents brief overview of psychological difficulties that occur as result of marital…

  6. Germanium blocked impurity band far infrared detectors

    SciTech Connect

    Rossington, C.S.

    1988-04-01

    The infrared portion of the electromagnetic spectrum has been of interest to scientist since the eighteenth century when Sir William Herschel discovered the infrared as he measured temperatures in the sun's spectrum and found that there was energy beyond the red. In the late nineteenth century, Thomas Edison established himself as the first infrared astronomer to look beyond the solar system when he observed the star Arcturus in the infrared. Significant advances in infrared technology and physics, long since Edison's time, have resulted in many scientific developments, such as the Infrared Astronomy Satellite (IRAS) which was launched in 1983, semiconductor infrared detectors for materials characterization, military equipment such as night-vision goggles and infrared surveillance equipment. It is now planned that cooled semiconductor infrared detectors will play a major role in the ''Star Wars'' nuclear defense scheme proposed by the Reagan administration.

  7. Linear cryogenic coolers for HOT infrared detectors

    NASA Astrophysics Data System (ADS)

    Veprik, A.; Riabzev, S.; Avishay, N.; Oster, D.; Tuitto, A.

    2012-06-01

    In spite of a wide spreading the uncooled night vision technologies, the cooled systems are still known to be superior in terms of working ranges, resolution and ability to recognize/track fast moving objects in dynamic infrared scenes. Recent technological advances allowed development and fielding of high temperature infrared detectors working up to 200K while showing performances typical for their 77K predecessors. The direct benefits of using such detectors are the lowering of the optical, cooling and packaging constraints resulting in smaller and cost effective optics, electronics and mechanical cryocooler. The authors are formulating requirements and general vision of prospective ultra-compact, long life, lightweight, power efficient, acoustically and dynamically quiet linear cryogenic cooler towards forthcoming infrared imagers. In particular, the authors are revealing the outcomes of the feasibility study and discuss downscaling options.

  8. Infrared SWAP detectors: pushing the limits

    NASA Astrophysics Data System (ADS)

    Reibel, Yann; Taalat, R.; Brunner, A.; Rubaldo, L.; Augey, T.; Kerlain, A.; Péré-Laperne, N.; Manissadjian, A.; Gravrand, O.; Castelein, P.; Destéfanis, G.

    2015-06-01

    The growing demand for compact and low consumption infrared cooled detectors is driven by different products segments. Hand Held Thermal Imagers, UAV, small gimbals are some of them. End users are requiring devices easy to use with fast cool down time, excellent portability, low acoustic noise with no trade-offs in reliability and performance. These requirements are pushing the technology developments toward constant innovations on detectors, coolers, read out circuits and proximity electronic boards. In this paper we are discussing the different figures of merit and highlighting the challenges for the different components. An update on the developments of HOT technology for most advanced pixel pitch will be presented. Very compact products are driving the developments for innovative coolers and cryogenic solutions. A low power compact architecture is a must for electronic boards to optimize the overall system power consumption. Finally a look to the future requirements for further shrink will be addressed.

  9. Heat Transfer Issues in Thin-Film Thermal Radiation Detectors

    NASA Technical Reports Server (NTRS)

    Barry, Mamadou Y.

    1999-01-01

    The Thermal Radiation Group at Virginia Polytechnic Institute and State University has been working closely with scientists and engineers at NASA's Langley Research Center to develop accurate analytical and numerical models suitable for designing next generation thin-film thermal radiation detectors for earth radiation budget measurement applications. The current study provides an analytical model of the notional thermal radiation detector that takes into account thermal transport phenomena, such as the contact resistance between the layers of the detector, and is suitable for use in parameter estimation. It was found that the responsivity of the detector can increase significantly due to the presence of contact resistance between the layers of the detector. Also presented is the effect of doping the thermal impedance layer of the detector with conducting particles in order to electrically link the two junctions of the detector. It was found that the responsivity and the time response of the doped detector decrease significantly in this case. The corresponding decrease of the electrical resistance of the doped thermal impedance layer is not sufficient to significantly improve the electrical performance of the detector. Finally, the "roughness effect" is shown to be unable to explain the decrease in the thermal conductivity often reported for thin-film layers.

  10. Approaching high temperature photon counting with electron-injection detectors

    NASA Astrophysics Data System (ADS)

    Fathipour, V.; Jang, S. J.; Hassaninia, I.; Mohseni, H.

    2014-10-01

    Our group has designed and developed a novel telecom band photon detector called the electron-injection detector. The detector provides a high avalanche-free internal-amplification and a stable excess noise factor of near unity while operating at linear-mode with low bias voltages. In our previous reports on un-isolated detectors, the large dark current of the detectors prevented long integration times in the camera. Furthermore, the bandwidth of the un-isolated detectors was in the KHz range. Recently, by changing the 3D geometry and isolating the detectors from each other, we have achieved 3 orders of magnitude reduction in dark current at same bias voltage and temperature compared to our previous results. Isolated detectors have internal dark current densities of 0.1nA/cm2 at 160 K. Furthermore, they have a bandwidth that is 4 orders of magnitude higher than the un-isolated devices. In this paper we report room temperature and low temperature characteristics of the isolated electron-injection detectors. We show that the measured optical gain displays a small dependence on temperature over our measured range down to 220 K.

  11. Advances in Nuclear Monitoring Technologies

    NASA Astrophysics Data System (ADS)

    Park, Brent

    2006-03-01

    Homeland security requires low-cost, large-area detectors for locating and identifying weapons-usable nuclear materials and monitors for radiological isotopes that are more robust than current systems. Recent advances in electronics materials and nanotechnology, specifically organic semiconductors and inorganic quantum dots, offer potential improvements. We provide an overview of the physical processes involved in radiation detection using these new materials in the design of new device structures. Examples include recent efforts on quantum dots, as well as more traditional radiation-detecting materials such as CdZnTe and high-pressure xenon. Detector improvements demand not only new materials but also enhanced data-analysis tools that reduce false alarms and thus increase the quality of decisions. Additional computing power on hand-held platforms should enable the application of advanced algorithms to radiation-detection problems in the field, reducing the need to transmit data and thus delay analysis.

  12. Optical detector calibrator system

    NASA Technical Reports Server (NTRS)

    Strobel, James P. (Inventor); Moerk, John S. (Inventor); Youngquist, Robert C. (Inventor)

    1996-01-01

    An optical detector calibrator system simulates a source of optical radiation to which a detector to be calibrated is responsive. A light source selected to emit radiation in a range of wavelengths corresponding to the spectral signature of the source is disposed within a housing containing a microprocessor for controlling the light source and other system elements. An adjustable iris and a multiple aperture filter wheel are provided for controlling the intensity of radiation emitted from the housing by the light source to adjust the simulated distance between the light source and the detector to be calibrated. The geared iris has an aperture whose size is adjustable by means of a first stepper motor controlled by the microprocessor. The multiple aperture filter wheel contains neutral density filters of different attenuation levels which are selectively positioned in the path of the emitted radiation by a second stepper motor that is also controlled by the microprocessor. An operator can select a number of detector tests including range, maximum and minimum sensitivity, and basic functionality. During the range test, the geared iris and filter wheel are repeatedly adjusted by the microprocessor as necessary to simulate an incrementally increasing simulated source distance. A light source calibration subsystem is incorporated in the system which insures that the intensity of the light source is maintained at a constant level over time.

  13. The Friendship Detector

    ERIC Educational Resources Information Center

    Cox, Scott

    2012-01-01

    After years of using Rube Goldberg-inspired projects to teach concepts of simple machines, the author sought a comparable project to reinforce electricity lessons in his ninth-grade Science and Technology course. The Friendship Detector gives students a chance to design, test, and build a complex circuit with multiple switches and battery-powered…

  14. Neutrino Detectors Review

    SciTech Connect

    D'Ambrosio, Nicola

    2005-10-12

    The neutrino physics is one of the most important research field and there are several experiments made and under construction focused on it. This paper will present a review on some detectors used for Solar Neutrinos detection, Atmospheric Neutrinos detection and in Long Baseline Experiments.

  15. Choosing a Motion Detector.

    ERIC Educational Resources Information Center

    Ballard, David M.

    1990-01-01

    Examines the characteristics of three types of motion detectors: Doppler radar, infrared, and ultrasonic wave, and how they are used on school buses to prevent students from being killed by their own school bus. Other safety devices cited are bus crossing arms and a camera monitor system. (MLF)

  16. Leak detector uses ultrasonics

    NASA Technical Reports Server (NTRS)

    Heisman, R. M.; Iceland, W. F.; Keir, A. R.

    1978-01-01

    Probe located on outer wall of vacuum-jacketed fluid lines detects leaks on inner wall. Probe picks up and amplifies vibrations that occur when gas rushes through leak and converts them to audible signal or CRT display. System is considerably simpler to use than helium leak detectors and allows rapid checks to be made as part of routine maintenance.

  17. Sensitive hydrogen leak detector

    DOEpatents

    Myneni, G.R.

    1999-08-03

    A sensitive hydrogen leak detector system is described which uses passivation of a stainless steel vacuum chamber for low hydrogen outgassing, a high compression ratio vacuum system, a getter operating at 77.5 K and a residual gas analyzer as a quantitative hydrogen sensor. 1 fig.

  18. Refrigerant leak detector

    NASA Technical Reports Server (NTRS)

    Byrne, E. J.

    1979-01-01

    Quantitative leak detector visually demonstrates refrigerant loss from precision volume of large refrigeration system over established period of time from single test point. Mechanical unit is less costly than electronic "sniffers" and is more reliable due to absence of electronic circuits that are susceptible to drift.

  19. Directional gamma detector

    DOEpatents

    LeVert, Francis E.; Cox, Samson A.

    1981-01-01

    An improved directional gamma radiation detector has a collector sandwiched etween two layers of insulation of varying thicknesses. The collector and insulation layers are contained within an evacuated casing, or emitter, which releases electrons upon exposure to gamma radiation. Delayed electrons and electrons entering the collector at oblique angles are attenuated as they pass through the insulation layers on route to the collector.

  20. Temperature stabilized phase detector

    NASA Technical Reports Server (NTRS)

    Lo, Y.

    1981-01-01

    The construction, tests, and performance of a temperature stabilized phase detector are discussed. It has a frequency stability of 5 parts in 10 to the 16th power at 100 MHz, with a temperature step of 20 C (15 to 35 C).