Advanced Digital Imaging Laboratory Using MATLAB® (Second edition)

NASA Astrophysics Data System (ADS)

Yaroslavsky, Leonid P.

2016-09-01

The first edition of this text book focussed on providing practical hands-on experience in digital imaging techniques for graduate students and practitioners keeping to a minimum any detailed discussion on the underlying theory. In this new extended edition, the author builds on the strength of the original edition by expanding the coverage to include formulation of the major theoretical results that underlie the exercises as well as introducing numerous modern concepts and new techniques. Whether you are studying or already using digital imaging techniques, developing proficiency in the subject is not possible without mastering practical skills. Including more than 100 MATLAB® exercises, this book delivers a complete applied course in digital imaging theory and practice. Part of IOP Series in Imaging Engineering Supplementary MATLAB codes and data files are available within Book Information.

An application of digital network technology to medical image management.

PubMed

Chu, W K; Smith, C L; Wobig, R K; Hahn, F A

1997-01-01

With the advent of network technology, there is considerable interest within the medical community to manage the storage and distribution of medical images by digital means. Higher workflow efficiency leading to better patient care is one of the commonly cited outcomes [1,2]. However, due to the size of medical image files and the unique requirements in detail and resolution, medical image management poses special challenges. Storage requirements are usually large, which implies expenses or investment costs make digital networking projects financially out of reach for many clinical institutions. New advances in network technology and telecommunication, in conjunction with the decreasing cost in computer devices, have made digital image management achievable. In our institution, we have recently completed a pilot project to distribute medical images both within the physical confines of the clinical enterprise as well as outside the medical center campus. The design concept and the configuration of a comprehensive digital image network is described in this report.

WE-D-BRD-01: Innovation in Radiation Therapy Delivery: Advanced Digital Linac Features

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xing, L; Wong, J; Li, R

2014-06-15

Last few years has witnessed significant advances in linac technology and therapeutic dose delivery method. Digital linacs equipped with high dose rate FFF beams have been clinically implemented in a number of hospitals. Gated VMAT is becoming increasingly popular in treating tumors affected by respiratory motion. This session is devoted to update the audience with these technical advances and to present our experience in clinically implementing the new linacs and dose delivery methods. Topics to be covered include, technical features of new generation of linacs from different vendors, dosimetric characteristics and clinical need for FFF-beam based IMRT and VMAT, respiration-gatedmore » VMAT, the concept and implementation of station parameter optimized radiation therapy (SPORT), beam level imaging and onboard image guidance tools. Emphasis will be on providing fundamental understanding of the new treatment delivery and image guidance strategies, control systems, and the associated dosimetric characteristics. Commissioning and acceptance experience on these new treatment delivery technologies will be reported. Clinical experience and challenges encountered during the process of implementation of the new treatment techniques and future applications of the systems will also be highlighted. Learning Objectives: Present background knowledge of emerging digital linacs and summarize their key geometric and dosimetric features. SPORT as an emerging radiation therapy modality specifically designed to take advantage of digital linacs. Discuss issues related to the acceptance and commissioning of the digital linacs and FFF beams. Describe clinical utility of the new generation of digital linacs and their future applications.« less

Utility of Digital Stereo Images for Optic Disc Evaluation

PubMed Central

Ying, Gui-shuang; Pearson, Denise J.; Bansal, Mayank; Puri, Manika; Miller, Eydie; Alexander, Judith; Piltz-Seymour, Jody; Nyberg, William; Maguire, Maureen G.; Eledath, Jayan; Sawhney, Harpreet

2010-01-01

Purpose. To assess the suitability of digital stereo images for optic disc evaluations in glaucoma. Methods. Stereo color optic disc images in both digital and 35-mm slide film formats were acquired contemporaneously from 29 subjects with various cup-to-disc ratios (range, 0.26–0.76; median, 0.475). Using a grading scale designed to assess image quality, the ease of visualizing optic disc features important for glaucoma diagnosis, and the comparative diameters of the optic disc cup, experienced observers separately compared the primary digital stereo images to each subject's 35-mm slides, to scanned images of the same 35-mm slides, and to grayscale conversions of the digital images. Statistical analysis accounted for multiple gradings and comparisons and also assessed image formats under monoscopic viewing. Results. Overall, the quality of primary digital color images was judged superior to that of 35-mm slides (P < 0.001), including improved stereo (P < 0.001), but the primary digital color images were mostly equivalent to the scanned digitized images of the same slides. Color seemingly added little to grayscale optic disc images, except that peripapillary atrophy was best seen in color (P < 0.0001); both the nerve fiber layer (P < 0.0001) and the paths of blood vessels on the optic disc (P < 0.0001) were best seen in grayscale. The preference for digital over film images was maintained under monoscopic viewing conditions. Conclusions. Digital stereo optic disc images are useful for evaluating the optic disc in glaucoma and allow the application of advanced image processing applications. Grayscale images, by providing luminance distinct from color, may be informative for assessing certain features. PMID:20505199

Recent advances in imaging technologies in dentistry.

PubMed

Shah, Naseem; Bansal, Nikhil; Logani, Ajay

2014-10-28

Dentistry has witnessed tremendous advances in all its branches over the past three decades. With these advances, the need for more precise diagnostic tools, specially imaging methods, have become mandatory. From the simple intra-oral periapical X-rays, advanced imaging techniques like computed tomography, cone beam computed tomography, magnetic resonance imaging and ultrasound have also found place in modern dentistry. Changing from analogue to digital radiography has not only made the process simpler and faster but also made image storage, manipulation (brightness/contrast, image cropping, etc.) and retrieval easier. The three-dimensional imaging has made the complex cranio-facial structures more accessible for examination and early and accurate diagnosis of deep seated lesions. This paper is to review current advances in imaging technology and their uses in different disciplines of dentistry.

Recent advances in imaging technologies in dentistry

PubMed Central

Shah, Naseem; Bansal, Nikhil; Logani, Ajay

2014-01-01

Dentistry has witnessed tremendous advances in all its branches over the past three decades. With these advances, the need for more precise diagnostic tools, specially imaging methods, have become mandatory. From the simple intra-oral periapical X-rays, advanced imaging techniques like computed tomography, cone beam computed tomography, magnetic resonance imaging and ultrasound have also found place in modern dentistry. Changing from analogue to digital radiography has not only made the process simpler and faster but also made image storage, manipulation (brightness/contrast, image cropping, etc.) and retrieval easier. The three-dimensional imaging has made the complex cranio-facial structures more accessible for examination and early and accurate diagnosis of deep seated lesions. This paper is to review current advances in imaging technology and their uses in different disciplines of dentistry. PMID:25349663

Imaging Emission Spectra with Handheld and Cellphone Cameras

ERIC Educational Resources Information Center

Sitar, David

2012-01-01

As point-and-shoot digital camera technology advances it is becoming easier to image spectra in a laboratory setting on a shoestring budget and get immediate results. With this in mind, I wanted to test three cameras to see how their results would differ. Two undergraduate physics students and I used one handheld 7.1 megapixel (MP) digital Cannon…

Image analysis in modern ophthalmology: from acquisition to computer assisted diagnosis and telemedicine

NASA Astrophysics Data System (ADS)

Marrugo, Andrés G.; Millán, María S.; Cristóbal, Gabriel; Gabarda, Salvador; Sorel, Michal; Sroubek, Filip

2012-06-01

Medical digital imaging has become a key element of modern health care procedures. It provides visual documentation and a permanent record for the patients, and most important the ability to extract information about many diseases. Modern ophthalmology thrives and develops on the advances in digital imaging and computing power. In this work we present an overview of recent image processing techniques proposed by the authors in the area of digital eye fundus photography. Our applications range from retinal image quality assessment to image restoration via blind deconvolution and visualization of structural changes in time between patient visits. All proposed within a framework for improving and assisting the medical practice and the forthcoming scenario of the information chain in telemedicine.

Carnegie Mellon University bioimaging day 2014: Challenges and opportunities in digital pathology

PubMed Central

Rohde, Gustavo K.; Ozolek, John A.; Parwani, Anil V.; Pantanowitz, Liron

2014-01-01

Recent advances in digital imaging is impacting the practice of pathology. One of the key enabling technologies that is leading the way towards this transformation is the use of whole slide imaging (WSI) which allows glass slides to be converted into large image files that can be shared, stored, and analyzed rapidly. Many applications around this novel technology have evolved in the last decade including education, research and clinical applications. This publication highlights a collection of abstracts, each corresponding to a talk given at Carnegie Mellon University's (CMU) Bioimaging Day 2014 co-sponsored by the Biomedical Engineering and Lane Center for Computational Biology Departments at CMU. Topics related specifically to digital pathology are presented in this collection of abstracts. These include topics related to digital workflow implementation, imaging and artifacts, storage demands, and automated image analysis algorithms. PMID:25250190

Carnegie Mellon University bioimaging day 2014: Challenges and opportunities in digital pathology.

PubMed

Rohde, Gustavo K; Ozolek, John A; Parwani, Anil V; Pantanowitz, Liron

2014-01-01

Recent advances in digital imaging is impacting the practice of pathology. One of the key enabling technologies that is leading the way towards this transformation is the use of whole slide imaging (WSI) which allows glass slides to be converted into large image files that can be shared, stored, and analyzed rapidly. Many applications around this novel technology have evolved in the last decade including education, research and clinical applications. This publication highlights a collection of abstracts, each corresponding to a talk given at Carnegie Mellon University's (CMU) Bioimaging Day 2014 co-sponsored by the Biomedical Engineering and Lane Center for Computational Biology Departments at CMU. Topics related specifically to digital pathology are presented in this collection of abstracts. These include topics related to digital workflow implementation, imaging and artifacts, storage demands, and automated image analysis algorithms.

Image understanding and the man-machine interface II; Proceedings of the Meeting, Los Angeles, CA, Jan. 17, 18, 1989

NASA Technical Reports Server (NTRS)

Barrett, Eamon B. (Editor); Pearson, James J. (Editor)

1989-01-01

Image understanding concepts and models, image understanding systems and applications, advanced digital processors and software tools, and advanced man-machine interfaces are among the topics discussed. Particular papers are presented on such topics as neural networks for computer vision, object-based segmentation and color recognition in multispectral images, the application of image algebra to image measurement and feature extraction, and the integration of modeling and graphics to create an infrared signal processing test bed.

Advanced X-ray Imaging Crystal Spectrometer for Magnetic Fusion Tokamak Devices

NASA Astrophysics Data System (ADS)

Lee, S. G.; Bak, J. G.; Bog, M. G.; Nam, U. W.; Moon, M. K.; Cheon, J. K.

2008-03-01

An advanced X-ray imaging crystal spectrometer is currently under development using a segmented position sensitive detector and time-to-digital converter (TDC) based delay-line readout electronics for burning plasma diagnostics. The proposed advanced XICS utilizes an eight-segmented position sensitive multi-wire proportional counter and supporting electronics to increase the spectrometer performance includes the photon count-rate capability and spatial resolution.

Regionally adaptive histogram equalization of the chest.

PubMed

Sherrier, R H; Johnson, G A

1987-01-01

Advances in the area of digital chest radiography have resulted in the acquisition of high-quality images of the human chest. With these advances, there arises a genuine need for image processing algorithms specific to the chest, in order to fully exploit this digital technology. We have implemented the well-known technique of histogram equalization, noting the problems encountered when it is adapted to chest images. These problems have been successfully solved with our regionally adaptive histogram equalization method. With this technique histograms are calculated locally and then modified according to both the mean pixel value of that region as well as certain characteristics of the cumulative distribution function. This process, which has allowed certain regions of the chest radiograph to be enhanced differentially, may also have broader implications for other image processing tasks.

Preliminary clinical evaluation of hard- and soft-copy digitized chest radiography

NASA Astrophysics Data System (ADS)

Rian, Roger L.; Smerud, Michael J.; Guinn, Todd

1994-05-01

The digital applications in radiology are a controversial advanced which potentially will influence all areas of patient imaging. It is utilized and accepted in angiography, computed tomography, magnetic resonance, nuclear imaging and sonography. More recently Computed Radiography has gained credibility in mobile scenarios as well as specific applications from cervical spine radiography to digital fluoroscopy. Usually this acceptance is related to benefits of lesser radiation exposure or an improved presentation with an incorrect radiographic technique. One advantage of interpreting from digital information is the potential manipulation of the image presentation to the observer through windowing, leveling and edge enhancement pre and/or during image review. Additionally this digital data can be transmitted over distance and represented as hard and/or soft copy for primary or consultative review. The number and quality of the images to be viewed, the environment of the review station as well as the observer experience with conventional radiographic as well as digital image evaluation are important aspects of delivering the radiologist's product i.e. the final interpretation. This paper assesses that product, specifically addressing the question `Is the radiologist's report the same whether derived from the original analog image or from its digitized image.' The object of this study is to determine whether a digital system (3M PACS) designed for consultative viewing in a satellite department can also be used directly for primary diagnosis of conventional chest exams.

Wavelet Compression of Satellite-Transmitted Digital Mammograms

NASA Technical Reports Server (NTRS)

Zheng, Yuan F.

2001-01-01

Breast cancer is one of the major causes of cancer death in women in the United States. The most effective way to treat breast cancer is to detect it at an early stage by screening patients periodically. Conventional film-screening mammography uses X-ray films which are effective in detecting early abnormalities of the breast. Direct digital mammography has the potential to improve the image quality and to take advantages of convenient storage, efficient transmission, and powerful computer-aided diagnosis, etc. One effective alternative to direct digital imaging is secondary digitization of X-ray films. This technique may not provide as high an image quality as the direct digital approach, but definitely have other advantages inherent to digital images. One of them is the usage of satellite-transmission technique for transferring digital mammograms between a remote image-acquisition site and a central image-reading site. This technique can benefit a large population of women who reside in remote areas where major screening and diagnosing facilities are not available. The NASA-Lewis Research Center (LeRC), in collaboration with the Cleveland Clinic Foundation (CCF), has begun a pilot study to investigate the application of the Advanced Communications Technology Satellite (ACTS) network to telemammography. The bandwidth of the T1 transmission is limited (1.544 Mbps) while the size of a mammographic image is huge. It takes a long time to transmit a single mammogram. For example, a mammogram of 4k by 4k pixels with 16 bits per pixel needs more than 4 minutes to transmit. Four images for a typical screening exam would take more than 16 minutes. This is too long a time period for a convenient screening. Consequently, compression is necessary for making satellite-transmission of mammographic images practically possible. The Wavelet Research Group of the Department of Electrical Engineering at The Ohio State University (OSU) participated in the LeRC-CCF collaboration by providing advanced compression technology using wavelet transform. OSU developed a time-efficient software package with various wavelets to compress a serious of mammographic images. This documents reports the result of the compression activities.

Earth Explorer

USGS Publications Warehouse

,

2000-01-01

The U.S. Geological Survey's (USGS) Earth Explorer Web site provides access to millions of land-related products, including the following: Satellite images from Landsat, advanced very high resolution radiometer (AVHRR), and Corona data sets. Aerial photographs from the National Aerial Photography Program, NASA, and USGS data sets.  Digital cartographic data from digital elevation models, digital line graphs, digital raster graphics, and digital orthophoto quadrangles. USGS paper maps Digital, film, and paper products are available, and many products can be previewed before ordering.

Shuttle imaging radar-C science plan

NASA Technical Reports Server (NTRS)

1986-01-01

The Shuttle Imaging Radar-C (SIR-C) mission will yield new and advanced scientific studies of the Earth. SIR-C will be the first instrument to simultaneously acquire images at L-band and C-band with HH, VV, HV, or VH polarizations, as well as images of the phase difference between HH and VV polarizations. These data will be digitally encoded and recorded using onboard high-density digital tape recorders and will later be digitally processed into images using the JPL Advanced Digital SAR Processor. SIR-C geologic studies include cold-region geomorphology, fluvial geomorphology, rock weathering and erosional processes, tectonics and geologic boundaries, geobotany, and radar stereogrammetry. Hydrology investigations cover arid, humid, wetland, snow-covered, and high-latitude regions. Additionally, SIR-C will provide the data to identify and map vegetation types, interpret landscape patterns and processes, assess the biophysical properties of plant canopies, and determine the degree of radar penetration of plant canopies. In oceanography, SIR-C will provide the information necessary to: forecast ocean directional wave spectra; better understand internal wave-current interactions; study the relationship of ocean-bottom features to surface expressions and the correlation of wind signatures to radar backscatter; and detect current-system boundaries, oceanic fronts, and mesoscale eddies. And, as the first spaceborne SAR with multi-frequency, multipolarization imaging capabilities, whole new areas of glaciology will be opened for study when SIR-C is flown in a polar orbit.

ACTS Satellite Telemammography Network Experiments

NASA Technical Reports Server (NTRS)

Kachmar, Brian A.; Kerczewski, Robert J.

2000-01-01

The Satellite Networks and Architectures Branch of NASA's Glenn Research Center has developed and demonstrated several advanced satellite communications technologies through the Advanced Communications Technology Satellite (ACTS) program. One of these technologies is the implementation of a Satellite Telemammography Network (STN) encompassing NASA Glenn, the Cleveland Clinic Foundation. the University of Virginia, and the Ashtabula County Medical Center. This paper will present a look at the STN from its beginnings to the impact it may have on future telemedicine applications. Results obtained using the experimental ACTS satellite demonstrate the feasibility of Satellite Telemammography. These results have improved teleradiology processes and mammography image manipulation, and enabled advances in remote screening methodologies. Future implementation of satellite telemammography using next generation commercial satellite networks will be explored. In addition, the technical aspects of the project will be discussed, in particular how the project has evolved from using NASA developed hardware and software to commercial off the shelf (COTS) products. Development of asymmetrical link technologies was an outcome of this work. Improvements in the display of digital mammographic images, better understanding of end-to-end system requirements, and advances in radiological image compression were achieved as a result of the research. Finally, rigorous clinical medical studies are required for new technologies such as digital satellite telemammography to gain acceptance in the medical establishment. These experiments produced data that were useful in two key medical studies that addressed the diagnostic accuracy of compressed satellite transmitted digital mammography images. The results of these studies will also be discussed.

An Innovative Method for Obtaining Consistent Images and Quantification of Histochemically Stained Specimens

PubMed Central

Sedgewick, Gerald J.; Ericson, Marna

2015-01-01

Obtaining digital images of color brightfield microscopy is an important aspect of biomedical research and the clinical practice of diagnostic pathology. Although the field of digital pathology has had tremendous advances in whole-slide imaging systems, little effort has been directed toward standardizing color brightfield digital imaging to maintain image-to-image consistency and tonal linearity. Using a single camera and microscope to obtain digital images of three stains, we show that microscope and camera systems inherently produce image-to-image variation. Moreover, we demonstrate that post-processing with a widely used raster graphics editor software program does not completely correct for session-to-session inconsistency. We introduce a reliable method for creating consistent images with a hardware/software solution (ChromaCal™; Datacolor Inc., NJ) along with its features for creating color standardization, preserving linear tonal levels, providing automated white balancing and setting automated brightness to consistent levels. The resulting image consistency using this method will also streamline mean density and morphometry measurements, as images are easily segmented and single thresholds can be used. We suggest that this is a superior method for color brightfield imaging, which can be used for quantification and can be readily incorporated into workflows. PMID:25575568

Processing Of Binary Images

NASA Astrophysics Data System (ADS)

Hou, H. S.

1985-07-01

An overview of the recent progress in the area of digital processing of binary images in the context of document processing is presented here. The topics covered include input scan, adaptive thresholding, halftoning, scaling and resolution conversion, data compression, character recognition, electronic mail, digital typography, and output scan. Emphasis has been placed on illustrating the basic principles rather than descriptions of a particular system. Recent technology advances and research in this field are also mentioned.

UNDERWATER MAPPING USING GLORIA AND MIPS.

USGS Publications Warehouse

Chavez, Pat S.; Anderson, Jeffrey A.; Schoonmaker, James W.

1987-01-01

Advances in digital image processing of the (GLORIA) Geological Long-Range Induced Asdic) sidescan-sonar image data have made it technically and economically possible to map large areas of the ocean floor including the Exclusive Economic Zone. Software was written to correct both geometric and radiometric distortions that exist in the original raw GLORIA data. A digital mosaicking technique was developed enabling 2 degree by 2 degree quadrangles to be generated.

Diagnostic Radiology--The Impact of New Technology.

ERIC Educational Resources Information Center

Harrison, R. M.

1989-01-01

Discussed are technological advances applying computer techniques for image acquisition and processing, including digital radiography, computed tomography, and nuclear magnetic resonance imaging. Several diagrams and pictures showing the use of each technique are presented. (YP)

Radiation dose and image quality of X-ray volume imaging systems: cone-beam computed tomography, digital subtraction angiography and digital fluoroscopy.

PubMed

Paul, Jijo; Jacobi, Volkmar; Farhang, Mohammad; Bazrafshan, Babak; Vogl, Thomas J; Mbalisike, Emmanuel C

2013-06-01

Radiation dose and image quality estimation of three X-ray volume imaging (XVI) systems. A total of 126 patients were examined using three XVI systems (groups 1-3) and their data were retrospectively analysed from 2007 to 2012. Each group consisted of 42 patients and each patient was examined using cone-beam computed tomography (CBCT), digital subtraction angiography (DSA) and digital fluoroscopy (DF). Dose parameters such as dose-area product (DAP), skin entry dose (SED) and image quality parameters such as Hounsfield unit (HU), noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were estimated and compared using appropriate statistical tests. Mean DAP and SED were lower in recent XVI than its previous counterparts in CBCT, DSA and DF. HU of all measured locations was non-significant between the groups except the hepatic artery. Noise showed significant difference among groups (P < 0.05). Regarding CNR and SNR, the recent XVI showed a higher and significant difference compared to its previous versions. Qualitatively, CBCT showed significance between versions unlike the DSA and DF which showed non-significance. A reduction of radiation dose was obtained for the recent-generation XVI system in CBCT, DSA and DF. Image noise was significantly lower; SNR and CNR were higher than in previous versions. The technological advancements and the reduction in the number of frames led to a significant dose reduction and improved image quality with the recent-generation XVI system. • X-ray volume imaging (XVI) systems are increasingly used for interventional radiological procedures. • More modern XVI systems use lower radiation doses compared with earlier counterparts. • Furthermore more modern XVI systems provide higher image quality. • Technological advances reduce radiation dose and improve image quality.

Optical Measurement Techniques for Rocket Engine Testing and Component Applications: Digital Image Correlation and Dynamic Photogrammetry

NASA Technical Reports Server (NTRS)

Gradl, Paul

2016-01-01

NASA Marshall Space Flight Center (MSFC) has been advancing dynamic optical measurement systems, primarily Digital Image Correlation, for extreme environment rocket engine test applications. The Digital Image Correlation (DIC) technology is used to track local and full field deformations, displacement vectors and local and global strain measurements. This technology has been evaluated at MSFC through lab testing to full scale hotfire engine testing of the J-2X Upper Stage engine at Stennis Space Center. It has been shown to provide reliable measurement data and has replaced many traditional measurement techniques for NASA applications. NASA and AMRDEC have recently signed agreements for NASA to train and transition the technology to applications for missile and helicopter testing. This presentation will provide an overview and progression of the technology, various testing applications at NASA MSFC, overview of Army-NASA test collaborations and application lessons learned about Digital Image Correlation.

Advanced imaging techniques II: using a compound microscope for photographing point-mount specimens

USDA-ARS?s Scientific Manuscript database

Digital imaging technology has revolutionized the practice photographing insects for scientific study. Herein described are lighting and mounting techniques designed for imaging micro Hymenoptera. Techniques described here are applicable to all small insects, as well as other invertebrates. The ke...

Advanced microlens and color filter process technology for the high-efficiency CMOS and CCD image sensors

NASA Astrophysics Data System (ADS)

Fan, Yang-Tung; Peng, Chiou-Shian; Chu, Cheng-Yu

2000-12-01

New markets are emerging for digital electronic image device, especially in visual communications, PC camera, mobile/cell phone, security system, toys, vehicle image system and computer peripherals for document capture. To enable one-chip image system that image sensor is with a full digital interface, can make image capture devices in our daily lives. Adding a color filter to such image sensor in a pattern of mosaics pixel or wide stripes can make image more real and colorful. We can say 'color filter makes the life more colorful color filter is? Color filter means can filter image light source except the color with specific wavelength and transmittance that is same as color filter itself. Color filter process is coating and patterning green, red and blue (or cyan, magenta and yellow) mosaic resists onto matched pixel in image sensing array pixels. According to the signal caught from each pixel, we can figure out the environment image picture. Widely use of digital electronic camera and multimedia applications today makes the feature of color filter becoming bright. Although it has challenge but it is very worthy to develop the process of color filter. We provide the best service on shorter cycle time, excellent color quality, high and stable yield. The key issues of advanced color process have to be solved and implemented are planarization and micro-lens technology. Lost of key points of color filter process technology have to consider will also be described in this paper.

Visual Communications And Image Processing

NASA Astrophysics Data System (ADS)

Hsing, T. Russell; Tzou, Kou-Hu

1989-07-01

This special issue on Visual Communications and Image Processing contains 14 papers that cover a wide spectrum in this fast growing area. For the past few decades, researchers and scientists have devoted their efforts to these fields. Through this long-lasting devotion, we witness today the growing popularity of low-bit-rate video as a convenient tool for visual communication. We also see the integration of high-quality video into broadband digital networks. Today, with more sophisticated processing, clearer and sharper pictures are being restored from blurring and noise. Also, thanks to the advances in digital image processing, even a PC-based system can be built to recognize highly complicated Chinese characters at the speed of 300 characters per minute. This special issue can be viewed as a milestone of visual communications and image processing on its journey to eternity. It presents some overviews on advanced topics as well as some new development in specific subjects.

Estimation of color modification in digital images by CFA pattern change.

PubMed

Choi, Chang-Hee; Lee, Hae-Yeoun; Lee, Heung-Kyu

2013-03-10

Extensive studies have been carried out for detecting image forgery such as copy-move, re-sampling, blurring, and contrast enhancement. Although color modification is a common forgery technique, there is no reported forensic method for detecting this type of manipulation. In this paper, we propose a novel algorithm for estimating color modification in images acquired from digital cameras when the images are modified. Most commercial digital cameras are equipped with a color filter array (CFA) for acquiring the color information of each pixel. As a result, the images acquired from such digital cameras include a trace from the CFA pattern. This pattern is composed of the basic red green blue (RGB) colors, and it is changed when color modification is carried out on the image. We designed an advanced intermediate value counting method for measuring the change in the CFA pattern and estimating the extent of color modification. The proposed method is verified experimentally by using 10,366 test images. The results confirmed the ability of the proposed method to estimate color modification with high accuracy. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

The use of low cost compact cameras with focus stacking functionality in entomological digitization projects

PubMed Central

Mertens, Jan E.J.; Roie, Martijn Van; Merckx, Jonas; Dekoninck, Wouter

2017-01-01

Abstract Digitization of specimen collections has become a key priority of many natural history museums. The camera systems built for this purpose are expensive, providing a barrier in institutes with limited funding, and therefore hampering progress. An assessment is made on whether a low cost compact camera with image stacking functionality can help expedite the digitization process in large museums or provide smaller institutes and amateur entomologists with the means to digitize their collections. Images of a professional setup were compared with the Olympus Stylus TG-4 Tough, a low-cost compact camera with internal focus stacking functions. Parameters considered include image quality, digitization speed, price, and ease-of-use. The compact camera’s image quality, although inferior to the professional setup, is exceptional considering its fourfold lower price point. Producing the image slices in the compact camera is a matter of seconds and when optimal image quality is less of a priority, the internal stacking function omits the need for dedicated stacking software altogether, further decreasing the cost and speeding up the process. In general, it is found that, aware of its limitations, this compact camera is capable of digitizing entomological collections with sufficient quality. As technology advances, more institutes and amateur entomologists will be able to easily and affordably catalogue their specimens. PMID:29134038

Physics and engineering aspects of cell and tissue imaging systems: microscopic devices and computer assisted diagnosis.

PubMed

Chen, Xiaodong; Ren, Liqiang; Zheng, Bin; Liu, Hong

2013-01-01

The conventional optical microscopes have been used widely in scientific research and in clinical practice. The modern digital microscopic devices combine the power of optical imaging and computerized analysis, archiving and communication techniques. It has a great potential in pathological examinations for improving the efficiency and accuracy of clinical diagnosis. This chapter reviews the basic optical principles of conventional microscopes, fluorescence microscopes and electron microscopes. The recent developments and future clinical applications of advanced digital microscopic imaging methods and computer assisted diagnosis schemes are also discussed.

An automated digital imaging system for environmental monitoring applications

USGS Publications Warehouse

Bogle, Rian; Velasco, Miguel; Vogel, John

2013-01-01

Recent improvements in the affordability and availability of high-resolution digital cameras, data loggers, embedded computers, and radio/cellular modems have advanced the development of sophisticated automated systems for remote imaging. Researchers have successfully placed and operated automated digital cameras in remote locations and in extremes of temperature and humidity, ranging from the islands of the South Pacific to the Mojave Desert and the Grand Canyon. With the integration of environmental sensors, these automated systems are able to respond to local conditions and modify their imaging regimes as needed. In this report we describe in detail the design of one type of automated imaging system developed by our group. It is easily replicated, low-cost, highly robust, and is a stand-alone automated camera designed to be placed in remote locations, without wireless connectivity.

Air Force Human Resources Laboratory Annual Report - Fiscal Year 1983.

DTIC Science & Technology

1984-08-01

were performed - digital image-generation visual system and three in the Advanced Simulator for Pilot Training at associated wide-angle windows. The...inputs by the trainee. This arrangement, and survivability in high-threat environments are , with its corresponding analog-to- digital interface... digitized models of various military vehicles and aircraft for continual update/expansion. Utilization: An interactive modeling system will be user

Study of fish response using particle image velocimetry and high-speed, high-resolution imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deng, Z.; Richmond, M. C.; Mueller, R. P.

2004-10-01

Fish swimming has fascinated both engineers and fish biologists for decades. Digital particle image velocimetry (DPIV) and high-speed, high-resolution digital imaging are recently developed analysis tools that can help engineers and biologists better understand how fish respond to turbulent environments. This report details studies to evaluate DPIV. The studies included a review of existing literature on DPIV, preliminary studies to test the feasibility of using DPIV conducted at our Flow Biology Laboratory in Richland, Washington September through December 2003, and applications of high-speed, high-resolution digital imaging with advanced motion analysis to investigations of fish injury mechanisms in turbulent shear flowsmore » and bead trajectories in laboratory physical models. Several conclusions were drawn based on these studies, which are summarized as recommendations for proposed research at the end of this report.« less

Fundamental Concepts of Digital Image Processing

DOE R&D Accomplishments Database

Twogood, R. E.

1983-03-01

The field of a digital-image processing has experienced dramatic growth and increasingly widespread applicability in recent years. Fortunately, advances in computer technology have kept pace with the rapid growth in volume of image data in these and other applications. Digital image processing has become economical in many fields of research and in industrial and military applications. While each application has requirements unique from the others, all are concerned with faster, cheaper, more accurate, and more extensive computation. The trend is toward real-time and interactive operations, where the user of the system obtains preliminary results within a short enough time that the next decision can be made by the human processor without loss of concentration on the task at hand. An example of this is the obtaining of two-dimensional (2-D) computer-aided tomography (CAT) images. A medical decision might be made while the patient is still under observation rather than days later.

Apollo Lunar Sample Photographs: Digitizing the Moon Rock Collection

NASA Technical Reports Server (NTRS)

Lofgren, Gary E.; Todd, Nancy S.; Runco, S. K.; Stefanov, W. L.

2011-01-01

The Acquisition and Curation Office at JSC has undertaken a 4-year data restoration project effort for the lunar science community funded by the LASER program (Lunar Advanced Science and Exploration Research) to digitize photographs of the Apollo lunar rock samples and create high resolution digital images. These sample photographs are not easily accessible outside of JSC, and currently exist only on degradable film in the Curation Data Storage Facility

Planetary cartography in the next decade: Digital cartography and emerging opportunities

NASA Technical Reports Server (NTRS)

1989-01-01

Planetary maps being produced today will represent views of the solar system for many decades to come. The primary objective of the planetary cartography program is to produce the most complete and accurate maps from hundreds of thousands of planetary images in support of scientific studies and future missions. Here, the utilization of digital techniques and digital bases in response to recent advances in computer technology are emphasized.

Aggressive driving video and non-contact enforcement (ADVANCE): drivers' reaction to violation notices : summary of survey results

DOT National Transportation Integrated Search

2001-01-01

ADVANCE is an integration of state of the practice, off-the-shelf technologies which include video, speed measurement, distance measurement, and digital imaging that detects UDAs in the traffic stream and subsequently notifies violators by ma...

Remote Histology Learning from Static versus Dynamic Microscopic Images

ERIC Educational Resources Information Center

Mione, Sylvia; Valcke, Martin; Cornelissen, Maria

2016-01-01

Histology is the study of microscopic structures in normal tissue sections. Curriculum redesign in medicine has led to a decrease in the use of optical microscopes during practical classes. Other imaging solutions have been implemented to facilitate remote learning. With advancements in imaging technologies, learning material can now be digitized.…

Study of signal-to-noise ratio in digital mammography

NASA Astrophysics Data System (ADS)

Kato, Yuri; Fujita, Naotoshi; Kodera, Yoshie

2009-02-01

Mammography techniques have recently advanced from those using analog systems (the screen-film system) to those using digital systems; for example, computed radiography (CR) and flat-panel detectors (FPDs) are nowadays used in mammography. Further, phase contrast mammography (PCM)-a digital technique by which images with a magnification of 1.75× can be obtained-is now available in the market. We studied the effect of the air gap in PCM and evaluated the effectiveness of an antiscatter x-ray grid in conventional mammography (CM) by measuring the scatter fraction ratio (SFR) and relative signal-to-noise ratio (rSNR) and comparing them between PCM and the digital CM. The results indicated that the SFRs for the CM images obtained with a grid were the lowest and that these ratios were almost the same as those for the PCM images. In contrast, the rSNRs for the PCM images were the highest, which means that the scattering of x-rays was sufficiently reduced by the air gap without the loss of primary x-rays.

Advanced IR System For Supersonic Boundary Layer Transition Flight Experiment

NASA Technical Reports Server (NTRS)

Banks, Daniel W.

2008-01-01

Infrared thermography is a preferred method investigating transition in flight: a) Global and non-intrusive; b) Can also be used to visualize and characterize other fluid mechanic phenomena such as shock impingement, separation etc. F-15 based system was updated with new camera and digital video recorder to support high Reynolds number transition tests. Digital Recording improves image quality and analysis capability and allows for accurate quantitative (temperature) measurements and greater enhancement through image processing allows analysis of smaller scale phenomena.

Imaging Emission Spectra with Handheld and Cellphone Cameras

NASA Astrophysics Data System (ADS)

Sitar, David

2012-12-01

As point-and-shoot digital camera technology advances it is becoming easier to image spectra in a laboralory setting on a shoestring budget and get immediale results. With this in mind, I wanted to test three cameras to see how their results would differ. Two undergraduate physics students and I used one handheld 7.1 megapixel (MP) digital Cannon point-and-shoot auto focusing camera and two different cellphone cameras: one at 6.1 MP and the other at 5.1 MP.

Digital stereoscopic cinema: the 21st century

NASA Astrophysics Data System (ADS)

Lipton, Lenny

2008-02-01

Over 1000 theaters in more than a dozen countries have been outfitted with digital projectors using the Texas Instruments DLP engine equipped to show field-sequential 3-D movies using the polarized method of image selection. Shuttering eyewear and advanced anaglyph products are also being deployed for image selection. Many studios are in production with stereoscopic films, and some have committed to producing their entire output of animated features in 3-D. This is a time of technology change for the motion picture industry.

Massively parallel information processing systems for space applications

NASA Technical Reports Server (NTRS)

Schaefer, D. H.

1979-01-01

NASA is developing massively parallel systems for ultra high speed processing of digital image data collected by satellite borne instrumentation. Such systems contain thousands of processing elements. Work is underway on the design and fabrication of the 'Massively Parallel Processor', a ground computer containing 16,384 processing elements arranged in a 128 x 128 array. This computer uses existing technology. Advanced work includes the development of semiconductor chips containing thousands of feedthrough paths. Massively parallel image analog to digital conversion technology is also being developed. The goal is to provide compact computers suitable for real-time onboard processing of images.

Computed tomography: Will the slices reveal the truth

PubMed Central

Haridas, Harish; Mohan, Abarajithan; Papisetti, Sravanthi; Ealla, Kranti K. R.

2016-01-01

With the advances in the field of imaging sciences, new methods have been developed in dental radiology. These include digital radiography, density analyzing methods, cone beam computed tomography (CBCT), magnetic resonance imaging, ultrasound, and nuclear imaging techniques, which provide high-resolution detailed images of oral structures. The current review aims to critically elaborate the use of CBCT in endodontics. PMID:27652253

CMOS Image Sensors: Electronic Camera On A Chip

NASA Technical Reports Server (NTRS)

Fossum, E. R.

1995-01-01

Recent advancements in CMOS image sensor technology are reviewed, including both passive pixel sensors and active pixel sensors. On- chip analog to digital converters and on-chip timing and control circuits permit realization of an electronic camera-on-a-chip. Highly miniaturized imaging systems based on CMOS image sensor technology are emerging as a competitor to charge-coupled devices for low cost uses.

Virtual medicine: Utilization of the advanced cardiac imaging patient avatar for procedural planning and facilitation.

PubMed

Shinbane, Jerold S; Saxon, Leslie A

Advances in imaging technology have led to a paradigm shift from planning of cardiovascular procedures and surgeries requiring the actual patient in a "brick and mortar" hospital to utilization of the digitalized patient in the virtual hospital. Cardiovascular computed tomographic angiography (CCTA) and cardiovascular magnetic resonance (CMR) digitalized 3-D patient representation of individual patient anatomy and physiology serves as an avatar allowing for virtual delineation of the most optimal approaches to cardiovascular procedures and surgeries prior to actual hospitalization. Pre-hospitalization reconstruction and analysis of anatomy and pathophysiology previously only accessible during the actual procedure could potentially limit the intrinsic risks related to time in the operating room, cardiac procedural laboratory and overall hospital environment. Although applications are specific to areas of cardiovascular specialty focus, there are unifying themes related to the utilization of technologies. The virtual patient avatar computer can also be used for procedural planning, computational modeling of anatomy, simulation of predicted therapeutic result, printing of 3-D models, and augmentation of real time procedural performance. Examples of the above techniques are at various stages of development for application to the spectrum of cardiovascular disease processes, including percutaneous, surgical and hybrid minimally invasive interventions. A multidisciplinary approach within medicine and engineering is necessary for creation of robust algorithms for maximal utilization of the virtual patient avatar in the digital medical center. Utilization of the virtual advanced cardiac imaging patient avatar will play an important role in the virtual health care system. Although there has been a rapid proliferation of early data, advanced imaging applications require further assessment and validation of accuracy, reproducibility, standardization, safety, efficacy, quality, cost effectiveness, and overall value to medical care. Copyright © 2018 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

MO-G-18A-01: Radiation Dose Reducing Strategies in CT, Fluoroscopy and Radiography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahesh, M; Gingold, E; Jones, A

2014-06-15

Advances in medical x-ray imaging have provided significant benefits to patient care. According to NCRP 160, there are more than 400 million x-ray procedures performed annually in the United States alone that contributes to nearly half of all the radiation exposure to the US population. Similar growth trends in medical x-ray imaging are observed worldwide. Apparent increase in number of medical x-ray imaging procedures, new protocols and the associated radiation dose and risk has drawn considerable attention. This has led to a number of technological innovations such as tube current modulation, iterative reconstruction algorithms, dose alerts, dose displays, flat panelmore » digital detectors, high efficient digital detectors, storage phosphor radiography, variable filters, etc. that are enabling users to acquire medical x-ray images at a much lower radiation dose. Along with these, there are number of radiation dose optimization strategies that users can adapt to effectively lower radiation dose in medical x-ray procedures. The main objectives of this SAM course are to provide information and how to implement the various radiation dose optimization strategies in CT, Fluoroscopy and Radiography. Learning Objectives: To update impact of technological advances on dose optimization in medical imaging. To identify radiation optimization strategies in computed tomography. To describe strategies for configuring fluoroscopic equipment that yields optimal images at reasonable radiation dose. To assess ways to configure digital radiography systems and recommend ways to improve image quality at optimal dose.« less

Five task clusters that enable efficient and effective digitization of biological collections

PubMed Central

Nelson, Gil; Paul, Deborah; Riccardi, Gregory; Mast, Austin R.

2012-01-01

Abstract This paper describes and illustrates five major clusters of related tasks (herein referred to as task clusters) that are common to efficient and effective practices in the digitization of biological specimen data and media. Examples of these clusters come from the observation of diverse digitization processes. The staff of iDigBio (The U.S. National Science Foundation’s National Resource for Advancing Digitization of Biological Collections) visited active biological and paleontological collections digitization programs for the purpose of documenting and assessing current digitization practices and tools. These observations identified five task clusters that comprise the digitization process leading up to data publication: (1) pre-digitization curation and staging, (2) specimen image capture, (3) specimen image processing, (4) electronic data capture, and (5) georeferencing locality descriptions. While not all institutions are completing each of these task clusters for each specimen, these clusters describe a composite picture of digitization of biological and paleontological specimens across the programs that were observed. We describe these clusters, three workflow patterns that dominate the implemention of these clusters, and offer a set of workflow recommendations for digitization programs. PMID:22859876

Breast Biopsy System

NASA Technical Reports Server (NTRS)

1994-01-01

Charge Coupled Devices (CCDs) are high technology silicon chips that connect light directly into electronic or digital images, which can be manipulated or enhanced by computers. When Goddard Space Flight Center (GSFC) scientists realized that existing CCD technology could not meet scientific requirements for the Hubble Space Telescope Imagining Spectrograph, GSFC contracted with Scientific Imaging Technologies, Inc. (SITe) to develop an advanced CCD. SITe then applied many of the NASA-driven enhancements to the manufacture of CCDs for digital mammography. The resulting device images breast tissue more clearly and efficiently. The LORAD Stereo Guide Breast Biopsy system incorporates SITe's CCD as part of a digital camera system that is replacing surgical biopsy in many cases. Known as stereotactic needle biopsy, it is performed under local anesthesia with a needle and saves women time, pain, scarring, radiation exposure and money.

Key Issues in the Analysis of Remote Sensing Data: A report on the workshop

NASA Technical Reports Server (NTRS)

Swain, P. H. (Principal Investigator)

1981-01-01

The procedures of a workshop assessing the state of the art of machine analysis of remotely sensed data are summarized. Areas discussed were: data bases, image registration, image preprocessing operations, map oriented considerations, advanced digital systems, artificial intelligence methods, image classification, and improved classifier training. Recommendations of areas for further research are presented.

Automated methods of tree boundary extraction and foliage transparency estimation from digital imagery

Treesearch

Sang-Mook Lee; Neil A. Clark; Philip A. Araman

2003-01-01

Foliage transparency in trees is an important indicator for forest health assessment. This paper helps advance transparency measurement research by presenting methods of automatic tree boundary extraction and foliage transparency estimation from digital images taken from the ground of open grown trees.Extraction of proper boundaries of tree crowns is the...

A Comparative Study of Microscopic Images Captured by a Box Type Digital Camera Versus a Standard Microscopic Photography Camera Unit

PubMed Central

Desai, Nandini J.; Gupta, B. D.; Patel, Pratik Narendrabhai

2014-01-01

Introduction: Obtaining images of slides viewed by a microscope can be invaluable for both diagnosis and teaching.They can be transferred among technologically-advanced hospitals for further consultation and evaluation. But a standard microscopic photography camera unit (MPCU)(MIPS-Microscopic Image projection System) is costly and not available in resource poor settings. The aim of our endeavour was to find a comparable and cheaper alternative method for photomicrography. Materials and Methods: We used a NIKON Coolpix S6150 camera (box type digital camera) with Olympus CH20i microscope and a fluorescent microscope for the purpose of this study. Results: We got comparable results for capturing images of light microscopy, but the results were not as satisfactory for fluorescent microscopy. Conclusion: A box type digital camera is a comparable, less expensive and convenient alternative to microscopic photography camera unit. PMID:25478350

Digital photography provides a fast, reliable, and noninvasive method to estimate anthocyanin pigment concentration in reproductive and vegetative plant tissues.

PubMed

Del Valle, José C; Gallardo-López, Antonio; Buide, Mª Luisa; Whittall, Justen B; Narbona, Eduardo

2018-03-01

Anthocyanin pigments have become a model trait for evolutionary ecology as they often provide adaptive benefits for plants. Anthocyanins have been traditionally quantified biochemically or more recently using spectral reflectance. However, both methods require destructive sampling and can be labor intensive and challenging with small samples. Recent advances in digital photography and image processing make it the method of choice for measuring color in the wild. Here, we use digital images as a quick, noninvasive method to estimate relative anthocyanin concentrations in species exhibiting color variation. Using a consumer-level digital camera and a free image processing toolbox, we extracted RGB values from digital images to generate color indices. We tested petals, stems, pedicels, and calyces of six species, which contain different types of anthocyanin pigments and exhibit different pigmentation patterns. Color indices were assessed by their correlation to biochemically determined anthocyanin concentrations. For comparison, we also calculated color indices from spectral reflectance and tested the correlation with anthocyanin concentration. Indices perform differently depending on the nature of the color variation. For both digital images and spectral reflectance, the most accurate estimates of anthocyanin concentration emerge from anthocyanin content-chroma ratio, anthocyanin content-chroma basic, and strength of green indices. Color indices derived from both digital images and spectral reflectance strongly correlate with biochemically determined anthocyanin concentration; however, the estimates from digital images performed better than spectral reflectance in terms of r 2 and normalized root-mean-square error. This was particularly noticeable in a species with striped petals, but in the case of striped calyces, both methods showed a comparable relationship with anthocyanin concentration. Using digital images brings new opportunities to accurately quantify the anthocyanin concentrations in both floral and vegetative tissues. This method is efficient, completely noninvasive, applicable to both uniform and patterned color, and works with samples of any size.

Advances in computer imaging/applications in facial plastic surgery.

PubMed

Papel, I D; Jiannetto, D F

1999-01-01

Rapidly progressing computer technology, ever-increasing expectations of patients, and a confusing medicolegal environment requires a clarification of the role of computer imaging/applications. Advances in computer technology and its applications are reviewed. A brief historical discussion is included for perspective. Improvements in both hardware and software with the advent of digital imaging have allowed great increases in speed and accuracy in patient imaging. This facilitates doctor-patient communication and possibly realistic patient expectations. Patients seeking cosmetic surgery now often expect preoperative imaging. Although society in general has become more litigious, a literature search up to 1998 reveals no lawsuits directly involving computer imaging. It appears that conservative utilization of computer imaging by the facial plastic surgeon may actually reduce liability and promote communication. Recent advances have significantly enhanced the value of computer imaging in the practice of facial plastic surgery. These technological advances in computer imaging appear to contribute a useful technique for the practice of facial plastic surgery. Inclusion of computer imaging should be given serious consideration as an adjunct to clinical practice.

High-fidelity video and still-image communication based on spectral information: natural vision system and its applications

NASA Astrophysics Data System (ADS)

Yamaguchi, Masahiro; Haneishi, Hideaki; Fukuda, Hiroyuki; Kishimoto, Junko; Kanazawa, Hiroshi; Tsuchida, Masaru; Iwama, Ryo; Ohyama, Nagaaki

2006-01-01

In addition to the great advancement of high-resolution and large-screen imaging technology, the issue of color is now receiving considerable attention as another aspect than the image resolution. It is difficult to reproduce the original color of subject in conventional imaging systems, and that obstructs the applications of visual communication systems in telemedicine, electronic commerce, and digital museum. To breakthrough the limitation of conventional RGB 3-primary systems, "Natural Vision" project aims at an innovative video and still-image communication technology with high-fidelity color reproduction capability, based on spectral information. This paper summarizes the results of NV project including the development of multispectral and multiprimary imaging technologies and the experimental investigations on the applications to medicine, digital archives, electronic commerce, and computer graphics.

An automated and universal method for measuring mean grain size from a digital image of sediment

USGS Publications Warehouse

Buscombe, Daniel D.; Rubin, David M.; Warrick, Jonathan A.

2010-01-01

Existing methods for estimating mean grain size of sediment in an image require either complicated sequences of image processing (filtering, edge detection, segmentation, etc.) or statistical procedures involving calibration. We present a new approach which uses Fourier methods to calculate grain size directly from the image without requiring calibration. Based on analysis of over 450 images, we found the accuracy to be within approximately 16% across the full range from silt to pebbles. Accuracy is comparable to, or better than, existing digital methods. The new method, in conjunction with recent advances in technology for taking appropriate images of sediment in a range of natural environments, promises to revolutionize the logistics and speed at which grain-size data may be obtained from the field.

The potential of digital dental radiography in recording the adductor sesamoid and the MP3 stages.

PubMed

Abdel-Kader, H M

1999-12-01

The current study was undertaken to evaluate the reliability of using a recent advance in clinical radiographic technique, digital dental radiography, in recording two growth indicators: the adductor sesamoid and MP3 stages. With an exposure time five times less than that used in the conventional approach, this method shows greatest flexibility in providing a high quality digitized radiographic images of the two growth indicators under investigation. Refereed Paper

Frequency Based Design Partitioning to Achieve Higher Throughput in Digital Cross Correlator for Aperture Synthesis Passive MMW Imager.

PubMed

Asif, Muhammad; Guo, Xiangzhou; Zhang, Jing; Miao, Jungang

2018-04-17

Digital cross-correlation is central to many applications including but not limited to Digital Image Processing, Satellite Navigation and Remote Sensing. With recent advancements in digital technology, the computational demands of such applications have increased enormously. In this paper we are presenting a high throughput digital cross correlator, capable of processing 1-bit digitized stream, at the rate of up to 2 GHz, simultaneously on 64 channels i.e., approximately 4 Trillion correlation and accumulation operations per second. In order to achieve higher throughput, we have focused on frequency based partitioning of our design and tried to minimize and localize high frequency operations. This correlator is designed for a Passive Millimeter Wave Imager intended for the detection of contraband items concealed on human body. The goals are to increase the system bandwidth, achieve video rate imaging, improve sensitivity and reduce the size. Design methodology is detailed in subsequent sections, elaborating the techniques enabling high throughput. The design is verified for Xilinx Kintex UltraScale device in simulation and the implementation results are given in terms of device utilization and power consumption estimates. Our results show considerable improvements in throughput as compared to our baseline design, while the correlator successfully meets the functional requirements.

The history of MR imaging as seen through the pages of radiology.

PubMed

Edelman, Robert R

2014-11-01

The first reports in Radiology pertaining to magnetic resonance (MR) imaging were published in 1980, 7 years after Paul Lauterbur pioneered the first MR images and 9 years after the first human computed tomographic images were obtained. Historical advances in the research and clinical applications of MR imaging very much parallel the remarkable advances in MR imaging technology. These advances can be roughly classified into hardware (eg, magnets, gradients, radiofrequency [RF] coils, RF transmitter and receiver, MR imaging-compatible biopsy devices) and imaging techniques (eg, pulse sequences, parallel imaging, and so forth). Image quality has been dramatically improved with the introduction of high-field-strength superconducting magnets, digital RF systems, and phased-array coils. Hybrid systems, such as MR/positron emission tomography (PET), combine the superb anatomic and functional imaging capabilities of MR imaging with the unsurpassed capability of PET to demonstrate tissue metabolism. Supported by the improvements in hardware, advances in pulse sequence design and image reconstruction techniques have spurred dramatic improvements in imaging speed and the capability for studying tissue function. In this historical review, the history of MR imaging technology and developing research and clinical applications, as seen through the pages of Radiology, will be considered.

Three-dimensional image signals: processing methods

NASA Astrophysics Data System (ADS)

Schiopu, Paul; Manea, Adrian; Craciun, Anca-Ileana; Craciun, Alexandru

2010-11-01

Over the years extensive studies have been carried out to apply coherent optics methods in real-time processing, communications and transmission image. This is especially true when a large amount of information needs to be processed, e.g., in high-resolution imaging. The recent progress in data-processing networks and communication systems has considerably increased the capacity of information exchange. We describe the results of literature investigation research of processing methods for the signals of the three-dimensional images. All commercially available 3D technologies today are based on stereoscopic viewing. 3D technology was once the exclusive domain of skilled computer-graphics developers with high-end machines and software. The images capture from the advanced 3D digital camera can be displayed onto screen of the 3D digital viewer with/ without special glasses. For this is needed considerable processing power and memory to create and render the complex mix of colors, textures, and virtual lighting and perspective necessary to make figures appear three-dimensional. Also, using a standard digital camera and a technique called phase-shift interferometry we can capture "digital holograms." These are holograms that can be stored on computer and transmitted over conventional networks. We present some research methods to process "digital holograms" for the Internet transmission and results.

From microscopy to whole slide digital images: a century and a half of image analysis.

PubMed

Taylor, Clive R

2011-12-01

In the year 1850, microscopes had evolved in quality to the point that the "first pathologists emerged from the treacherous swamps of medieval practice onto the relatively firm ground that histopathology seemed to offer." These early pathologists began to practice the art of image analysis, and diagnostic surgical pathology was born. Today the traditional microscope, in the hands of an experienced pathologist, is established as the gold standard for diagnosis of cancer and other diseases. Nonetheless, it is a tool and a technology that is more than 150 years old. Rapid advances in the capabilities of digital imaging hardware and software now offer the real possibility of moving to a new level of practice, using whole slide digital images for diagnosis, education, and research in morphologic pathology. Potential efficiencies in work flow and diagnostic integration, coupled with the use of powerful new analytic methods, promise radically to change the future shape of surgical pathology.

Evaluation Digital Elevation Model Generated by Synthetic Aperture Radar Data

NASA Astrophysics Data System (ADS)

Makineci, H. B.; Karabörk, H.

2016-06-01

Digital elevation model, showing the physical and topographical situation of the earth, is defined a tree-dimensional digital model obtained from the elevation of the surface by using of selected an appropriate interpolation method. DEMs are used in many areas such as management of natural resources, engineering and infrastructure projects, disaster and risk analysis, archaeology, security, aviation, forestry, energy, topographic mapping, landslide and flood analysis, Geographic Information Systems (GIS). Digital elevation models, which are the fundamental components of cartography, is calculated by many methods. Digital elevation models can be obtained terrestrial methods or data obtained by digitization of maps by processing the digital platform in general. Today, Digital elevation model data is generated by the processing of stereo optical satellite images, radar images (radargrammetry, interferometry) and lidar data using remote sensing and photogrammetric techniques with the help of improving technology. One of the fundamental components of remote sensing radar technology is very advanced nowadays. In response to this progress it began to be used more frequently in various fields. Determining the shape of topography and creating digital elevation model comes the beginning topics of these areas. It is aimed in this work , the differences of evaluation of quality between Sentinel-1A SAR image ,which is sent by European Space Agency ESA and Interferometry Wide Swath imaging mode and C band type , and DTED-2 (Digital Terrain Elevation Data) and application between them. The application includes RMS static method for detecting precision of data. Results show us to variance of points make a high decrease from mountain area to plane area.

A new set of wavelet- and fractals-based features for Gleason grading of prostate cancer histopathology images

NASA Astrophysics Data System (ADS)

Mosquera Lopez, Clara; Agaian, Sos

2013-02-01

Prostate cancer detection and staging is an important step towards patient treatment selection. Advancements in digital pathology allow the application of new quantitative image analysis algorithms for computer-assisted diagnosis (CAD) on digitized histopathology images. In this paper, we introduce a new set of features to automatically grade pathological images using the well-known Gleason grading system. The goal of this study is to classify biopsy images belonging to Gleason patterns 3, 4, and 5 by using a combination of wavelet and fractal features. For image classification we use pairwise coupling Support Vector Machine (SVM) classifiers. The accuracy of the system, which is close to 97%, is estimated through three different cross-validation schemes. The proposed system offers the potential for automating classification of histological images and supporting prostate cancer diagnosis.

ARIES: Enabling Visual Exploration and Organization of Art Image Collections.

PubMed

Crissaff, Lhaylla; Wood Ruby, Louisa; Deutch, Samantha; DuBois, R Luke; Fekete, Jean-Daniel; Freire, Juliana; Silva, Claudio

2018-01-01

Art historians have traditionally used physical light boxes to prepare exhibits or curate collections. On a light box, they can place slides or printed images, move the images around at will, group them as desired, and visual-ly compare them. The transition to digital images has rendered this workflow obsolete. Now, art historians lack well-designed, unified interactive software tools that effectively support the operations they perform with physi-cal light boxes. To address this problem, we designed ARIES (ARt Image Exploration Space), an interactive image manipulation system that enables the exploration and organization of fine digital art. The system allows images to be compared in multiple ways, offering dynamic overlays analogous to a physical light box, and sup-porting advanced image comparisons and feature-matching functions, available through computational image processing. We demonstrate the effectiveness of our system to support art historians tasks through real use cases.

A comprehensive study on urban true orthorectification

USGS Publications Warehouse

Zhou, G.; Chen, W.; Kelmelis, J.A.; Zhang, Dongxiao

2005-01-01

To provide some advanced technical bases (algorithms and procedures) and experience needed for national large-scale digital orthophoto generation and revision of the Standards for National Large-Scale City Digital Orthophoto in the National Digital Orthophoto Program (NDOP), this paper presents a comprehensive study on theories, algorithms, and methods of large-scale urban orthoimage generation. The procedures of orthorectification for digital terrain model (DTM)-based and digital building model (DBM)-based orthoimage generation and their mergence for true orthoimage generation are discussed in detail. A method of compensating for building occlusions using photogrammetric geometry is developed. The data structure needed to model urban buildings for accurately generating urban orthoimages is presented. Shadow detection and removal, the optimization of seamline for automatic mosaic, and the radiometric balance of neighbor images are discussed. Street visibility analysis, including the relationship between flight height, building height, street width, and relative location of the street to the imaging center, is analyzed for complete true orthoimage generation. The experimental results demonstrated that our method can effectively and correctly orthorectify the displacements caused by terrain and buildings in urban large-scale aerial images. ?? 2005 IEEE.

A Review of Digital Image Correlation Applied to Structura Dynamics

NASA Astrophysics Data System (ADS)

Niezrecki, Christopher; Avitabile, Peter; Warren, Christopher; Pingle, Pawan; Helfrick, Mark

2010-05-01

A significant amount of interest exists in performing non-contacting, full-field surface velocity measurement. For many years traditional non-contacting surface velocity measurements have been made by using scanning Doppler laser vibrometry, shearography, pulsed laser interferometry, pulsed holography, or an electronic speckle pattern interferometer (ESPI). Three dimensional (3D) digital image correlation (DIC) methods utilize the alignment of a stereo pair of images to obtain full-field geometry data, in three dimensions. Information about the change in geometry of an object over time can be found by comparing a sequence of images and virtual strain gages (or position sensors) can be created over the entire visible surface of the object of interest. Digital imaging techniques were first developed in the 1980s but the technology has only recently been exploited in industry and research due to the advances of digital cameras and personal computers. The use of DIC for structural dynamic measurement has only very recently been investigated. Within this paper, the advantages and limits of using DIC for dynamic measurement are reviewed. Several examples of using DIC for dynamic measurement are presented on several vibrating and rotating structures.

Recent advances in standards for collaborative Digital Anatomic Pathology

PubMed Central

2011-01-01

Context Collaborative Digital Anatomic Pathology refers to the use of information technology that supports the creation and sharing or exchange of information, including data and images, during the complex workflow performed in an Anatomic Pathology department from specimen reception to report transmission and exploitation. Collaborative Digital Anatomic Pathology can only be fully achieved using medical informatics standards. The goal of the international integrating the Healthcare Enterprise (IHE) initiative is precisely specifying how medical informatics standards should be implemented to meet specific health care needs and making systems integration more efficient and less expensive. Objective To define the best use of medical informatics standards in order to share and exchange machine-readable structured reports and their evidences (including whole slide images) within hospitals and across healthcare facilities. Methods Specific working groups dedicated to Anatomy Pathology within multiple standards organizations defined standard-based data structures for Anatomic Pathology reports and images as well as informatic transactions in order to integrate Anatomic Pathology information into the electronic healthcare enterprise. Results The DICOM supplements 122 and 145 provide flexible object information definitions dedicated respectively to specimen description and Whole Slide Image acquisition, storage and display. The content profile “Anatomic Pathology Structured Report” (APSR) provides standard templates for structured reports in which textual observations may be bound to digital images or regions of interest. Anatomic Pathology observations are encoded using an international controlled vocabulary defined by the IHE Anatomic Pathology domain that is currently being mapped to SNOMED CT concepts. Conclusion Recent advances in standards for Collaborative Digital Anatomic Pathology are a unique opportunity to share or exchange Anatomic Pathology structured reports that are interoperable at an international level. The use of machine-readable format of APSR supports the development of decision support as well as secondary use of Anatomic Pathology information for epidemiology or clinical research. PMID:21489187

Digital micromirror devices: principles and applications in imaging.

PubMed

Bansal, Vivek; Saggau, Peter

2013-05-01

A digital micromirror device (DMD) is an array of individually switchable mirrors that can be used in many advanced optical systems as a rapid spatial light modulator. With a DMD, several implementations of confocal microscopy, hyperspectral imaging, and fluorescence lifetime imaging can be realized. The DMD can also be used as a real-time optical processor for applications such as the programmable array microscope and compressive sensing. Advantages and disadvantages of the DMD for these applications as well as methods to overcome some of the limitations will be discussed in this article. Practical considerations when designing with the DMD and sample optical layouts of a completely DMD-based imaging system and one in which acousto-optic deflectors (AODs) are used in the illumination pathway are also provided.

Applications of iQID cameras

NASA Astrophysics Data System (ADS)

Han, Ling; Miller, Brian W.; Barrett, Harrison H.; Barber, H. Bradford; Furenlid, Lars R.

2017-09-01

iQID is an intensified quantum imaging detector developed in the Center for Gamma-Ray Imaging (CGRI). Originally called BazookaSPECT, iQID was designed for high-resolution gamma-ray imaging and preclinical gamma-ray single-photon emission computed tomography (SPECT). With the use of a columnar scintillator, an image intensifier and modern CCD/CMOS sensors, iQID cameras features outstanding intrinsic spatial resolution. In recent years, many advances have been achieved that greatly boost the performance of iQID, broadening its applications to cover nuclear and particle imaging for preclinical, clinical and homeland security settings. This paper presents an overview of the recent advances of iQID technology and its applications in preclinical and clinical scintigraphy, preclinical SPECT, particle imaging (alpha, neutron, beta, and fission fragment), and digital autoradiography.

Digital radiographic imaging transfer: comparison with plain radiographs.

PubMed

Averch, T D; O'Sullivan, D; Breitenbach, C; Beser, N; Schulam, P G; Moore, R G; Kavoussi, L R

1997-04-01

Advances in digital imaging and computer display technology have allowed development of clinical teleradiographic systems. There are limited data assessing the effectiveness of such systems when applied to urologic pathology. In an effort to appraise the effectiveness of teleradiology in identifying renal calculi, the accuracy of findings on transmitted radiographic images were compared with those made when viewing the actual plain film. Plain films (KUB) were obtained from 26 patients who presented to the radiology department to rule out urinary calculous disease. The films were digitalized by a radiograph scanner into ARCNEMA-2 file format, compressed by a NASA algorithm, and transferred via a 28.8-kbps modern over standard telephone lines to a remote section 25 miles away, where they were decompressed and viewed on a 1600 x 1200-pixel monitor. Two attending urologists and two endourologic fellows were randomized to read either the transmitted image or the original radiograph with minimal clinical history provided. Of the 26 plain radiographic films, 24 were correctly interpreted by the fellows and 25 by the attending physicians (92% and 96% accuracy, respectively) for a total accuracy of 94% with no statistical difference (p = 0.16). After compression, all but one of the digital images were transferred successfully. The attending physicians correctly interpreted 24 of the 25 digital images (96%), whereas the fellows were correct on 21 interpretations (84%), resulting in a total 90% accuracy with a significant difference between the groups (p < or = 0.04). Overall, no statistical difference between the interpretations of the plain film and the digital image was revealed (p = 0.21). Using available technology, KUB images can be transmitted to a remote site, and the location of a stone can be determined correctly. Higher accuracy is demonstrated by experienced surgeons.

Emerging Themes in Image Informatics and Molecular Analysis for Digital Pathology.

PubMed

Bhargava, Rohit; Madabhushi, Anant

2016-07-11

Pathology is essential for research in disease and development, as well as for clinical decision making. For more than 100 years, pathology practice has involved analyzing images of stained, thin tissue sections by a trained human using an optical microscope. Technological advances are now driving major changes in this paradigm toward digital pathology (DP). The digital transformation of pathology goes beyond recording, archiving, and retrieving images, providing new computational tools to inform better decision making for precision medicine. First, we discuss some emerging innovations in both computational image analytics and imaging instrumentation in DP. Second, we discuss molecular contrast in pathology. Molecular DP has traditionally been an extension of pathology with molecularly specific dyes. Label-free, spectroscopic images are rapidly emerging as another important information source, and we describe the benefits and potential of this evolution. Third, we describe multimodal DP, which is enabled by computational algorithms and combines the best characteristics of structural and molecular pathology. Finally, we provide examples of application areas in telepathology, education, and precision medicine. We conclude by discussing challenges and emerging opportunities in this area.

Emerging Themes in Image Informatics and Molecular Analysis for Digital Pathology

PubMed Central

Bhargava, Rohit; Madabhushi, Anant

2017-01-01

Pathology is essential for research in disease and development, as well as for clinical decision making. For more than 100 years, pathology practice has involved analyzing images of stained, thin tissue sections by a trained human using an optical microscope. Technological advances are now driving major changes in this paradigm toward digital pathology (DP). The digital transformation of pathology goes beyond recording, archiving, and retrieving images, providing new computational tools to inform better decision making for precision medicine. First, we discuss some emerging innovations in both computational image analytics and imaging instrumentation in DP. Second, we discuss molecular contrast in pathology. Molecular DP has traditionally been an extension of pathology with molecularly specific dyes. Label-free, spectroscopic images are rapidly emerging as another important information source, and we describe the benefits and potential of this evolution. Third, we describe multimodal DP, which is enabled by computational algorithms and combines the best characteristics of structural and molecular pathology. Finally, we provide examples of application areas in telepathology, education, and precision medicine. We conclude by discussing challenges and emerging opportunities in this area. PMID:27420575

Increasing the efficiency of digitization workflows for herbarium specimens.

PubMed

Tulig, Melissa; Tarnowsky, Nicole; Bevans, Michael; Anthony Kirchgessner; Thiers, Barbara M

2012-01-01

The New York Botanical Garden Herbarium has been databasing and imaging its estimated 7.3 million plant specimens for the past 17 years. Due to the size of the collection, we have been selectively digitizing fundable subsets of specimens, making successive passes through the herbarium with each new grant. With this strategy, the average rate for databasing complete records has been 10 specimens per hour. With 1.3 million specimens databased, this effort has taken about 130,000 hours of staff time. At this rate, to complete the herbarium and digitize the remaining 6 million specimens, another 600,000 hours would be needed. Given the current biodiversity and economic crises, there is neither the time nor money to complete the collection at this rate.Through a combination of grants over the last few years, The New York Botanical Garden has been testing new protocols and tactics for increasing the rate of digitization through combinations of data collaboration, field book digitization, partial data entry and imaging, and optical character recognition (OCR) of specimen images. With the launch of the National Science Foundation's new Advancing Digitization of Biological Collections program, we hope to move forward with larger, more efficient digitization projects, capturing data from larger portions of the herbarium at a fraction of the cost and time.

Increasing the efficiency of digitization workflows for herbarium specimens

PubMed Central

Tulig, Melissa; Tarnowsky, Nicole; Bevans, Michael; Anthony Kirchgessner; Thiers,  Barbara M.

2012-01-01

Abstract The New York Botanical Garden Herbarium has been databasing and imaging its estimated 7.3 million plant specimens for the past 17 years. Due to the size of the collection, we have been selectively digitizing fundable subsets of specimens, making successive passes through the herbarium with each new grant. With this strategy, the average rate for databasing complete records has been 10 specimens per hour. With 1.3 million specimens databased, this effort has taken about 130,000 hours of staff time. At this rate, to complete the herbarium and digitize the remaining 6 million specimens, another 600,000 hours would be needed. Given the current biodiversity and economic crises, there is neither the time nor money to complete the collection at this rate. Through a combination of grants over the last few years, The New York Botanical Garden has been testing new protocols and tactics for increasing the rate of digitization through combinations of data collaboration, field book digitization, partial data entry and imaging, and optical character recognition (OCR) of specimen images. With the launch of the National Science Foundation’s new Advancing Digitization of Biological Collections program, we hope to move forward with larger, more efficient digitization projects, capturing data from larger portions of the herbarium at a fraction of the cost and time. PMID:22859882

The Convergence of Information Technology, Data, and Management in a Library Imaging Program

ERIC Educational Resources Information Center

France, Fenella G.; Emery, Doug; Toth, Michael B.

2010-01-01

Integrating advanced imaging and processing capabilities in libraries, archives, and museums requires effective systems and information management to ensure that the large amounts of digital data about cultural artifacts can be readily acquired, stored, archived, accessed, processed, and linked to other data. The Library of Congress is developing…

Benefit from NASA

NASA Image and Video Library

1985-01-01

The NASA imaging processing technology, an advanced computer technique to enhance images sent to Earth in digital form by distant spacecraft, helped develop a new vision screening process. The Ocular Vision Screening system, an important step in preventing vision impairment, is a portable device designed especially to detect eye problems in children through the analysis of retinal reflexes.

Control Software for Advanced Video Guidance Sensor

NASA Technical Reports Server (NTRS)

Howard, Richard T.; Book, Michael L.; Bryan, Thomas C.

2006-01-01

Embedded software has been developed specifically for controlling an Advanced Video Guidance Sensor (AVGS). A Video Guidance Sensor is an optoelectronic system that provides guidance for automated docking of two vehicles. Such a system includes pulsed laser diodes and a video camera, the output of which is digitized. From the positions of digitized target images and known geometric relationships, the relative position and orientation of the vehicles are computed. The present software consists of two subprograms running in two processors that are parts of the AVGS. The subprogram in the first processor receives commands from an external source, checks the commands for correctness, performs commanded non-image-data-processing control functions, and sends image data processing parts of commands to the second processor. The subprogram in the second processor processes image data as commanded. Upon power-up, the software performs basic tests of functionality, then effects a transition to a standby mode. When a command is received, the software goes into one of several operational modes (e.g. acquisition or tracking). The software then returns, to the external source, the data appropriate to the command.

[Digital breast tomosynthesis : technical principles, current clinical relevance and future perspectives].

PubMed

Hellerhoff, K

2010-11-01

In recent years digital full field mammography has increasingly replaced conventional film mammography. High quality imaging is guaranteed by high quantum efficiency and very good contrast resolution with optimized dosing even for women with dense glandular tissue. However, digital mammography remains a projection procedure by which overlapping tissue limits the detectability of subtle alterations. Tomosynthesis is a procedure developed from digital mammography for slice examination of breasts which eliminates the effects of overlapping tissue and allows 3D imaging of breasts. A curved movement of the X-ray tube during scanning allows the acquisition of many 2D images from different angles. Subseqently, reconstruction algorithms employing a shift and add method improve the recognition of details at a defined level and at the same time eliminate smear artefacts due to overlapping structures. The total dose corresponds to that of conventional mammography imaging. The technical procedure, including the number of levels, suitable anodes/filter combinations, angle regions of images and selection of reconstruction algorithms, is presently undergoing optimization. Previous studies on the clinical value of tomosynthesis have examined screening parameters, such as recall rate and detection rate as well as information on tumor extent for histologically proven breast tumors. More advanced techniques, such as contrast medium-enhanced tomosynthesis, are presently under development and dual-energy imaging is of particular importance.

Applications of image processing and visualization in the evaluation of murder and assault

NASA Astrophysics Data System (ADS)

Oliver, William R.; Rosenman, Julian G.; Boxwala, Aziz; Stotts, David; Smith, John; Soltys, Mitchell; Symon, James; Cullip, Tim; Wagner, Glenn

1994-09-01

Recent advances in image processing and visualization are of increasing use in the investigation of violent crime. The Digital Image Processing Laboratory at the Armed Forces Institute of Pathology in collaboration with groups at the University of North Carolina at Chapel Hill are actively exploring visualization applications including image processing of trauma images, 3D visualization, forensic database management and telemedicine. Examples of recent applications are presented. Future directions of effort include interactive consultation and image manipulation tools for forensic data exploration.

Advances in biologically inspired on/near sensor processing

NASA Astrophysics Data System (ADS)

McCarley, Paul L.

1999-07-01

As electro-optic sensors increase in size and frame rate, the data transfer and digital processing resource requirements also increase. In many missions, the spatial area of interest is but a small fraction of the available field of view. Choosing the right region of interest, however, is a challenge and still requires an enormous amount of downstream digital processing resources. In order to filter this ever-increasing amount of data, we look at how nature solves the problem. The Advanced Guidance Division of the Munitions Directorate, Air Force Research Laboratory at Elgin AFB, Florida, has been pursuing research in the are of advanced sensor and image processing concepts based on biologically inspired sensory information processing. A summary of two 'neuromorphic' processing efforts will be presented along with a seeker system concept utilizing this innovative technology. The Neuroseek program is developing a 256 X 256 2-color dual band IRFPA coupled to an optimized silicon CMOS read-out and processing integrated circuit that provides simultaneous full-frame imaging in MWIR/LWIR wavebands along with built-in biologically inspired sensor image processing functions. Concepts and requirements for future such efforts will also be discussed.

A new full-field digital mammography system with and without the use of an advanced post-processing algorithm: comparison of image quality and diagnostic performance.

PubMed

Ahn, Hye Shin; Kim, Sun Mi; Jang, Mijung; Yun, Bo La; Kim, Bohyoung; Ko, Eun Sook; Han, Boo-Kyung; Chang, Jung Min; Yi, Ann; Cho, Nariya; Moon, Woo Kyung; Choi, Hye Young

2014-01-01

To compare new full-field digital mammography (FFDM) with and without use of an advanced post-processing algorithm to improve image quality, lesion detection, diagnostic performance, and priority rank. During a 22-month period, we prospectively enrolled 100 cases of specimen FFDM mammography (Brestige®), which was performed alone or in combination with a post-processing algorithm developed by the manufacturer: group A (SMA), specimen mammography without application of "Mammogram enhancement ver. 2.0"; group B (SMB), specimen mammography with application of "Mammogram enhancement ver. 2.0". Two sets of specimen mammographies were randomly reviewed by five experienced radiologists. Image quality, lesion detection, diagnostic performance, and priority rank with regard to image preference were evaluated. Three aspects of image quality (overall quality, contrast, and noise) of the SMB were significantly superior to those of SMA (p < 0.05). SMB was significantly superior to SMA for visualizing calcifications (p < 0.05). Diagnostic performance, as evaluated by cancer score, was similar between SMA and SMB. SMB was preferred to SMA by four of the five reviewers. The post-processing algorithm may improve image quality with better image preference in FFDM than without use of the software.

Advanced Topics in Space Situational Awareness

DTIC Science & Technology

2007-11-07

34super-resolution." Such optical superresolution is characteristic of many model-based image processing algorithms, and reflects the incorporation of...Sampling Theorem," J. Opt. Soc. Am. A, vol. 24, 311-325 (2007). [39] S. Prasad, "Digital and Optical Superresolution of Low-Resolution Image Sequences," Un...wavefront coding for the specific application of extension of image depth well beyond what is possible in a standard imaging system. The problem of optical

Development of ultra-high temperature material characterization capabilities using digital image correlation analysis

NASA Astrophysics Data System (ADS)

Cline, Julia Elaine

2011-12-01

Ultra-high temperature deformation measurements are required to characterize the thermo-mechanical response of material systems for thermal protection systems for aerospace applications. The use of conventional surface-contacting strain measurement techniques is not practical in elevated temperature conditions. Technological advancements in digital imaging provide impetus to measure full-field displacement and determine strain fields with sub-pixel accuracy by image processing. In this work, an Instron electromechanical axial testing machine with a custom-designed high temperature gripping mechanism is used to apply quasi-static tensile loads to graphite specimens heated to 2000°F (1093°C). Specimen heating via Joule effect is achieved and maintained with a custom-designed temperature control system. Images are captured at monotonically increasing load levels throughout the test duration using an 18 megapixel Canon EOS Rebel T2i digital camera with a modified Schneider Kreutznach telecentric lens and a combination of blue light illumination and narrow band-pass filter system. Images are processed using an open-source Matlab-based digital image correlation (DIC) code. Validation of source code is performed using Mathematica generated images with specified known displacement fields in order to gain confidence in accurate software tracking capabilities. Room temperature results are compared with extensometer readings. Ultra-high temperature strain measurements for graphite are obtained at low load levels, demonstrating the potential for non-contacting digital image correlation techniques to accurately determine full-field strain measurements at ultra-high temperature. Recommendations are given to improve the experimental set-up to achieve displacement field measurements accurate to 1/10 pixel and strain field accuracy of less than 2%.

Programmed database system at the Chang Gung Craniofacial Center: part II--digitizing photographs.

PubMed

Chuang, Shiow-Shuh; Hung, Kai-Fong; de Villa, Glenda H; Chen, Philip K T; Lo, Lun-Jou; Chang, Sophia C N; Yu, Chung-Chih; Chen, Yu-Ray

2003-07-01

The archival tools used for digital images in advertising are not to fulfill the clinic requisition and are just beginning to develop. The storage of a large amount of conventional photographic slides needs a lot of space and special conditions. In spite of special precautions, degradation of the slides still occurs. The most common degradation is the appearance of fungus flecks. With the recent advances in digital technology, it is now possible to store voluminous numbers of photographs on a computer hard drive and keep them for a long time. A self-programmed interface has been developed to integrate database and image browser system that can build and locate needed files archive in a matter of seconds with the click of a button. This system requires hardware and software were market provided. There are 25,200 patients recorded in the database that involve 24,331 procedures. In the image files, there are 6,384 patients with 88,366 digital pictures files. From 1999 through 2002, NT400,000 dollars have been saved using the new system. Photographs can be managed with the integrating Database and Browse software for database archiving. This allows labeling of the individual photographs with demographic information and browsing. Digitized images are not only more efficient and economical than the conventional slide images, but they also facilitate clinical studies.

GLOBECOM '87 - Global Telecommunications Conference, Tokyo, Japan, Nov. 15-18, 1987, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference on global telecommunications discusses topics in the fields of Integrated Services Digital Network (ISDN) technology field trial planning and results to date, motion video coding, ISDN networking, future network communications security, flexible and intelligent voice/data networks, Asian and Pacific lightwave and radio systems, subscriber radio systems, the performance of distributed systems, signal processing theory, satellite communications modulation and coding, and terminals for the handicapped. Also discussed are knowledge-based technologies for communications systems, future satellite transmissions, high quality image services, novel digital signal processors, broadband network access interface, traffic engineering for ISDN design and planning, telecommunications software, coherent optical communications, multimedia terminal systems, advanced speed coding, portable and mobile radio communications, multi-Gbit/second lightwave transmission systems, enhanced capability digital terminals, communications network reliability, advanced antimultipath fading techniques, undersea lightwave transmission, image coding, modulation and synchronization, adaptive signal processing, integrated optical devices, VLSI technologies for ISDN, field performance of packet switching, CSMA protocols, optical transport system architectures for broadband ISDN, mobile satellite communications, indoor wireless communication, echo cancellation in communications, and distributed network algorithms.

A Macintosh-Based Scientific Images Video Analysis System

NASA Technical Reports Server (NTRS)

Groleau, Nicolas; Friedland, Peter (Technical Monitor)

1994-01-01

A set of experiments was designed at MIT's Man-Vehicle Laboratory in order to evaluate the effects of zero gravity on the human orientation system. During many of these experiments, the movements of the eyes are recorded on high quality video cassettes. The images must be analyzed off-line to calculate the position of the eyes at every moment in time. To this aim, I have implemented a simple inexpensive computerized system which measures the angle of rotation of the eye from digitized video images. The system is implemented on a desktop Macintosh computer, processes one play-back frame per second and exhibits adequate levels of accuracy and precision. The system uses LabVIEW, a digital output board, and a video input board to control a VCR, digitize video images, analyze them, and provide a user friendly interface for the various phases of the process. The system uses the Concept Vi LabVIEW library (Graftek's Image, Meudon la Foret, France) for image grabbing and displaying as well as translation to and from LabVIEW arrays. Graftek's software layer drives an Image Grabber board from Neotech (Eastleigh, United Kingdom). A Colour Adapter box from Neotech provides adequate video signal synchronization. The system also requires a LabVIEW driven digital output board (MacADIOS II from GW Instruments, Cambridge, MA) controlling a slightly modified VCR remote control used mainly to advance the video tape frame by frame.

Deep Learning Nuclei Detection in Digitized Histology Images by Superpixels.

PubMed

Sornapudi, Sudhir; Stanley, Ronald Joe; Stoecker, William V; Almubarak, Haidar; Long, Rodney; Antani, Sameer; Thoma, George; Zuna, Rosemary; Frazier, Shelliane R

2018-01-01

Advances in image analysis and computational techniques have facilitated automatic detection of critical features in histopathology images. Detection of nuclei is critical for squamous epithelium cervical intraepithelial neoplasia (CIN) classification into normal, CIN1, CIN2, and CIN3 grades. In this study, a deep learning (DL)-based nuclei segmentation approach is investigated based on gathering localized information through the generation of superpixels using a simple linear iterative clustering algorithm and training with a convolutional neural network. The proposed approach was evaluated on a dataset of 133 digitized histology images and achieved an overall nuclei detection (object-based) accuracy of 95.97%, with demonstrated improvement over imaging-based and clustering-based benchmark techniques. The proposed DL-based nuclei segmentation Method with superpixel analysis has shown improved segmentation results in comparison to state-of-the-art methods.

Efficient image acquisition design for a cancer detection system

NASA Astrophysics Data System (ADS)

Nguyen, Dung; Roehrig, Hans; Borders, Marisa H.; Fitzpatrick, Kimberly A.; Roveda, Janet

2013-09-01

Modern imaging modalities, such as Computed Tomography (CT), Digital Breast Tomosynthesis (DBT) or Magnetic Resonance Tomography (MRT) are able to acquire volumetric images with an isotropic resolution in micrometer (um) or millimeter (mm) range. When used in interactive telemedicine applications, these raw images need a huge storage unit, thereby necessitating the use of high bandwidth data communication link. To reduce the cost of transmission and enable archiving, especially for medical applications, image compression is performed. Recent advances in compression algorithms have resulted in a vast array of data compression techniques, but because of the characteristics of these images, there are challenges to overcome to transmit these images efficiently. In addition, the recent studies raise the low dose mammography risk on high risk patient. Our preliminary studies indicate that by bringing the compression before the analog-to-digital conversion (ADC) stage is more efficient than other compression techniques after the ADC. The linearity characteristic of the compressed sensing and ability to perform the digital signal processing (DSP) during data conversion open up a new area of research regarding the roles of sparsity in medical image registration, medical image analysis (for example, automatic image processing algorithm to efficiently extract the relevant information for the clinician), further Xray dose reduction for mammography, and contrast enhancement.

Application development environment for advanced digital workstations

NASA Astrophysics Data System (ADS)

Valentino, Daniel J.; Harreld, Michael R.; Liu, Brent J.; Brown, Matthew S.; Huang, Lu J.

1998-06-01

One remaining barrier to the clinical acceptance of electronic imaging and information systems is the difficulty in providing intuitive access to the information needed for a specific clinical task (such as reaching a diagnosis or tracking clinical progress). The purpose of this research was to create a development environment that enables the design and implementation of advanced digital imaging workstations. We used formal data and process modeling to identify the diagnostic and quantitative data that radiologists use and the tasks that they typically perform to make clinical decisions. We studied a diverse range of radiology applications, including diagnostic neuroradiology in an academic medical center, pediatric radiology in a children's hospital, screening mammography in a breast cancer center, and thoracic radiology consultation for an oncology clinic. We used object- oriented analysis to develop software toolkits that enable a programmer to rapidly implement applications that closely match clinical tasks. The toolkits support browsing patient information, integrating patient images and reports, manipulating images, and making quantitative measurements on images. Collectively, we refer to these toolkits as the UCLA Digital ViewBox toolkit (ViewBox/Tk). We used the ViewBox/Tk to rapidly prototype and develop a number of diverse medical imaging applications. Our task-based toolkit approach enabled rapid and iterative prototyping of workstations that matched clinical tasks. The toolkit functionality and performance provided a 'hands-on' feeling for manipulating images, and for accessing textual information and reports. The toolkits directly support a new concept for protocol based-reading of diagnostic studies. The design supports the implementation of network-based application services (e.g., prefetching, workflow management, and post-processing) that will facilitate the development of future clinical applications.

Segmenting Images for a Better Diagnosis

NASA Technical Reports Server (NTRS)

2004-01-01

NASA's Hierarchical Segmentation (HSEG) software has been adapted by Bartron Medical Imaging, LLC, for use in segmentation feature extraction, pattern recognition, and classification of medical images. Bartron acquired licenses from NASA Goddard Space Flight Center for application of the HSEG concept to medical imaging, from the California Institute of Technology/Jet Propulsion Laboratory to incorporate pattern-matching software, and from Kennedy Space Center for data-mining and edge-detection programs. The Med-Seg[TM] united developed by Bartron provides improved diagnoses for a wide range of medical images, including computed tomography scans, positron emission tomography scans, magnetic resonance imaging, ultrasound, digitized Z-ray, digitized mammography, dental X-ray, soft tissue analysis, and moving object analysis. It also can be used in analysis of soft-tissue slides. Bartron's future plans include the application of HSEG technology to drug development. NASA is advancing it's HSEG software to learn more about the Earth's magnetosphere.

Issues in using whole slide imaging for diagnostic pathology: "routine" stains, immunohistochemistry and predictive markers.

PubMed

Taylor, C R

2014-08-01

The traditional microscope, together with the "routine" hematoxylin and eosin (H & E) stain, remains the "gold standard" for diagnosis of cancer and other diseases; remarkably, it and the majority of associated biological stains are more than 150 years old. Immunohistochemistry has added to the repertoire of "stains" available. Because of the need for specific identification and even measurement of "biomarkers," immunohistochemistry has increased the demand for consistency of performance and interpretation of staining results. Rapid advances in the capabilities of digital imaging hardware and software now offer a realistic route to improved reproducibility, accuracy and quantification by utilizing whole slide digital images for diagnosis, education and research. There also are potential efficiencies in work flow and the promise of powerful new analytical methods; however, there also are challenges with respect to validation of the quality and fidelity of digital images, including the standard H & E stain, so that diagnostic performance by pathologists is not compromised when they rely on whole slide images instead of traditional stained tissues on glass slides.

Image interpolation and denoising for division of focal plane sensors using Gaussian processes.

PubMed

Gilboa, Elad; Cunningham, John P; Nehorai, Arye; Gruev, Viktor

2014-06-16

Image interpolation and denoising are important techniques in image processing. These methods are inherent to digital image acquisition as most digital cameras are composed of a 2D grid of heterogeneous imaging sensors. Current polarization imaging employ four different pixelated polarization filters, commonly referred to as division of focal plane polarization sensors. The sensors capture only partial information of the true scene, leading to a loss of spatial resolution as well as inaccuracy of the captured polarization information. Interpolation is a standard technique to recover the missing information and increase the accuracy of the captured polarization information. Here we focus specifically on Gaussian process regression as a way to perform a statistical image interpolation, where estimates of sensor noise are used to improve the accuracy of the estimated pixel information. We further exploit the inherent grid structure of this data to create a fast exact algorithm that operates in ����(N(3/2)) (vs. the naive ���� (N³)), thus making the Gaussian process method computationally tractable for image data. This modeling advance and the enabling computational advance combine to produce significant improvements over previously published interpolation methods for polarimeters, which is most pronounced in cases of low signal-to-noise ratio (SNR). We provide the comprehensive mathematical model as well as experimental results of the GP interpolation performance for division of focal plane polarimeter.

Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer

ClinicalTrials.gov

2013-03-11

1、Enough Cases; 2、Elekta Precise 1343 Digital Control Electron Linear Accelerator; Can Undertake Nasopharyngeal Carcinoma Specimens in the Materia，; Image Department of Nose Pharynx Ministry MRI Dynamic Testing,

Entomological Collections in the Age of Big Data.

PubMed

Short, Andrew Edward Z; Dikow, Torsten; Moreau, Corrie S

2018-01-07

With a million described species and more than half a billion preserved specimens, the large scale of insect collections is unequaled by those of any other group. Advances in genomics, collection digitization, and imaging have begun to more fully harness the power that such large data stores can provide. These new approaches and technologies have transformed how entomological collections are managed and utilized. While genomic research has fundamentally changed the way many specimens are collected and curated, advances in technology have shown promise for extracting sequence data from the vast holdings already in museums. Efforts to mainstream specimen digitization have taken root and have accelerated traditional taxonomic studies as well as distribution modeling and global change research. Emerging imaging technologies such as microcomputed tomography and confocal laser scanning microscopy are changing how morphology can be investigated. This review provides an overview of how the realization of big data has transformed our field and what may lie in store.

Camera Concepts for the Advanced Gamma-Ray Imaging System (AGIS)

NASA Astrophysics Data System (ADS)

Nepomuk Otte, Adam

2009-05-01

The Advanced Gamma-Ray Imaging System (AGIS) is a concept for the next generation observatory in ground-based very high energy gamma-ray astronomy. Design goals are ten times better sensitivity, higher angular resolution, and a lower energy threshold than existing Cherenkov telescopes. Each telescope is equipped with a camera that detects and records the Cherenkov-light flashes from air showers. The camera is comprised of a pixelated focal plane of blue sensitive and fast (nanosecond) photon detectors that detect the photon signal and convert it into an electrical one. The incorporation of trigger electronics and signal digitization into the camera are under study. Given the size of AGIS, the camera must be reliable, robust, and cost effective. We are investigating several directions that include innovative technologies such as Geiger-mode avalanche-photodiodes as a possible detector and switched capacitor arrays for the digitization.

Informatics for practicing anatomical pathologists: marking a new era in pathology practice.

PubMed

Gabril, Manal Y; Yousef, George M

2010-03-01

Informatics can be defined as using highly advanced technologies to improve patient diagnosis or management. Pathology informatics had evolved as a response to the overwhelming amount of information that was available, in an attempt to better use and maintain them. The most commonly used tools of informatics can be classified into digital imaging, telepathology, as well as Internet and electronic data mining. Digital imaging is the storage of anatomical pathology information, either gross pictures or microscopic slides, in an electronic format. These images can be used for education, archival, diagnosis, and consultation. Virtual microscopy is the more advanced form of digital imaging with enhanced efficiency and accessibility. Telepathology is now increasingly becoming a useful tool in anatomical pathology practice. Different types of telepathology communications are available for both diagnostic and consultation services. The spectrum of applications of informatics in the field of anatomical pathology is broad and encompasses medical education, clinical services, and pathology research. Informatics is now settling on solid ground as an important tool for pathology teaching, with digital teaching becoming the standard tool in many institutions. After a slow start, we now witness the transition of informatics from the research bench to bedside. As we are moving into a new era of extensive pathology informatics utilization, several challenges have to be addressed, including the cost of the new technology, legal issues, and resistance of pathologists. It is clear from the current evidence that pathology informatics will continue to grow and have a major role in the future of our specialty. However, it is also clear that it is not going to fully replace the human factor or the regular microscope.

Technological advances that enhance teaching using animals, and the application of the Three Rs.

PubMed

Davies, Alexander S

2004-06-01

The inventions that have progressively contributed to education have never offered opportunities as vast as in the digital era, even though this is still scarcely 25 years old. In this time, digital handling of data led first to text processing, then to bitmap and vector graphics, and now, to digital sound and movies. As these advanced, the storage methods became larger, faster, easier and cheaper. The advancement of technology has been so rapid that the standard of most teaching aids now available is well below what can currently be achieved. We are confronted with an unprecedented opportunity for applying the principles of reduction, refinement and replacement of animals in education. Not only are the visual teaching aids improved by digitising, but all aspects of their development, including the ease, higher speed, and low cost of creation, editing, copying, distribution and access, are improved, as well. Several examples will be given, including access to interactive panoramic movies, animated sequences to explain difficult concepts, on-line tutorials and image databases using digital photography, radiography and other diagnostic methods, as well as the production of desktop movies. The speed of technical advance brings its own problems, but the challenges and possibilities for developing viable alternatives to the use of animals in teaching are vast.

Integrating advanced visualization technology into the planetary Geoscience workflow

NASA Astrophysics Data System (ADS)

Huffman, John; Forsberg, Andrew; Loomis, Andrew; Head, James; Dickson, James; Fassett, Caleb

2011-09-01

Recent advances in computer visualization have allowed us to develop new tools for analyzing the data gathered during planetary missions, which is important, since these data sets have grown exponentially in recent years to tens of terabytes in size. As part of the Advanced Visualization in Solar System Exploration and Research (ADVISER) project, we utilize several advanced visualization techniques created specifically with planetary image data in mind. The Geoviewer application allows real-time active stereo display of images, which in aggregate have billions of pixels. The ADVISER desktop application platform allows fast three-dimensional visualization of planetary images overlain on digital terrain models. Both applications include tools for easy data ingest and real-time analysis in a programmatic manner. Incorporation of these tools into our everyday scientific workflow has proved important for scientific analysis, discussion, and publication, and enabled effective and exciting educational activities for students from high school through graduate school.

Digital photography in skin cancer screening by mobile units in remote areas of Brazil.

PubMed

Silveira, Carlos Eduardo Goulart; Silva, Thiago Buosi; Fregnani, José Humberto Guerreiro Tavares; da Costa Vieira, René Aloisio; Haikel, Raphael Luiz; Syrjänen, Kari; Carvalho, André Lopes; Mauad, Edmundo Carvalho

2014-12-24

Non-melanoma skin cancer (NMSC) is one of the most common neoplasms in the world. Despite the low mortality rates, NMSC can still cause severe sequelae when diagnosed at advanced stages. Malignant melanoma, the third most common type of skin cancer, has more aggressive behavior and a worse prognosis. Teledermatology provides a new tool for monitoring skin cancer, especially in countries with a large area and unequal population distribution. This study sought to evaluate the performance of digital photography in skin cancer diagnosis in remote areas of Brazil. A physician in a Mobile Prevention Unit (MPU) took four hundred sixteen digital images of suspicious lesions between April 2010 and July 2011. All of the photographs were electronically sent to two oncologists at Barretos Cancer Hospital who blindly evaluated the images and provided a diagnosis (benign or malignant). The absolute agreement rates between the diagnoses made by direct visual inspection (by the MPU physician) and through the use of digital imaging (by the two oncologists) were calculated. The oncologists' accuracy in predicting skin cancer using digital imaging was assessed by means of overall accuracy (correct classification rate), sensitivity, specificity and predictive value (positive and negative). A skin biopsy was considered the gold standard. Oncologist #1 classified 59 lesions as benign with the digital images, while oncologist #2 classified 27 lesions as benign using the same images. The absolute agreement rates with direct visual inspection were 85.8% for oncologist #1 (95% CI: 77.1-95.2) and 93.5% for oncologist #2 (95% CI: 84.5-100.0). The overall accuracy of the two oncologists did not differ significantly. Given the high sensitivity and PPV, Teledermatology seems to be a suitable tool for skin cancer screening by MPU in remote areas of Brazil.

The treatment of tendon injury with electromagnetic fields evidenced by advanced ultrasound image processing.

PubMed

Parker, Richard; Markov, Marko

2015-09-01

This article presents a novel modality for accelerating the repair of tendon and ligament lesions by means of a specifically designed electromagnetic field in an equine model. This novel therapeutic approach employs a delivery system that induces a specific electrical signal from an external magnetic field derived from Superconductive QUantum Interference Device (SQUID) measurements of injured vs. healthy tissue. Evaluation of this therapy technique is enabled by a proposed new technology described as Predictive Analytical Imagery (PAI™). This technique examines an ultrasound grayscale image and seeks to evaluate it by means of look-ahead predictive algorithms and digital signal processing. The net result is a significant reduction in background noise and the production of a high-resolution grayscale or digital image.

Large-scale quantitative analysis of painting arts.

PubMed

Kim, Daniel; Son, Seung-Woo; Jeong, Hawoong

2014-12-11

Scientists have made efforts to understand the beauty of painting art in their own languages. As digital image acquisition of painting arts has made rapid progress, researchers have come to a point where it is possible to perform statistical analysis of a large-scale database of artistic paints to make a bridge between art and science. Using digital image processing techniques, we investigate three quantitative measures of images - the usage of individual colors, the variety of colors, and the roughness of the brightness. We found a difference in color usage between classical paintings and photographs, and a significantly low color variety of the medieval period. Interestingly, moreover, the increment of roughness exponent as painting techniques such as chiaroscuro and sfumato have advanced is consistent with historical circumstances.

Advanced endoscopic imaging: European Society of Gastrointestinal Endoscopy (ESGE) Technology Review.

PubMed

East, James E; Vleugels, Jasper L; Roelandt, Philip; Bhandari, Pradeep; Bisschops, Raf; Dekker, Evelien; Hassan, Cesare; Horgan, Gareth; Kiesslich, Ralf; Longcroft-Wheaton, Gaius; Wilson, Ana; Dumonceau, Jean-Marc

2016-11-01

Background and aim: This technical review is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the utilization of advanced endoscopic imaging in gastrointestinal (GI) endoscopy. Methods: This technical review is based on a systematic literature search to evaluate the evidence supporting the use of advanced endoscopic imaging throughout the GI tract. Technologies considered include narrowed-spectrum endoscopy (narrow band imaging [NBI]; flexible spectral imaging color enhancement [FICE]; i-Scan digital contrast [I-SCAN]), autofluorescence imaging (AFI), and confocal laser endomicroscopy (CLE). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was adopted to define the strength of recommendation and the quality of evidence. Main recommendations: 1. We suggest advanced endoscopic imaging technologies improve mucosal visualization and enhance fine structural and microvascular detail. Expert endoscopic diagnosis may be improved by advanced imaging, but as yet in community-based practice no technology has been shown consistently to be diagnostically superior to current practice with high definition white light. (Low quality evidence.) 2. We recommend the use of validated classification systems to support the use of optical diagnosis with advanced endoscopic imaging in the upper and lower GI tracts (strong recommendation, moderate quality evidence). 3. We suggest that training improves performance in the use of advanced endoscopic imaging techniques and that it is a prerequisite for use in clinical practice. A learning curve exists and training alone does not guarantee sustained high performances in clinical practice. (Weak recommendation, low quality evidence.) Conclusion: Advanced endoscopic imaging can improve mucosal visualization and endoscopic diagnosis; however it requires training and the use of validated classification systems. © Georg Thieme Verlag KG Stuttgart · New York.

How many times can we use a phosphor plate? A preliminary study.

PubMed

Ergün, S; Güneri, P; Ilgüy, D; Ilgüy, M; Boyacioglu, H

2009-01-01

Digital radiography has become a useful tool in daily dental practice due to the advances in imaging technologies. Charge coupled devices (CCDs) and photostimulable phosphor plates (PSPs) are currently in use for dental imaging; however, the longevity of PSPs in dental practice is not yet established. The aim of this study was to determine the service life of PSPs in a clinical setting. Five unused PSPs were exposed with a conventional X-ray device and converted into digital images with Digora Optime (Soredex, Milwaukee, WI). These were recorded as the baseline images. Subsequent digital images of the plates were obtained after 20, 40, 60, 80, 100, 120, 140, 160, 180 and 200 exposures. All radiographic images were subtracted from the first digital image (baseline) and the mean grey values (MGVs) of the subtracted images were established using software. The data were grouped in 3 classes according to the number of exposures (20-80; 100-140; 160-200), and were analysed using variance analysis and chi(2) tests. The MGVs of the subtracted images varied between 126.25 and 127.59, and the difference was not significant among the groups (P = 0.11). However, the differences between the MGVs of the plates on each exposure settings were significantly different than those of the baseline image (P < 0.05). The findings of this study revealed that even though a slight deterioration occurred after the first exposure, each plate can be used up to 200 times. Further studies are required to reach a more concrete conclusion.

Bits and bytes: the future of radiology lies in informatics and information technology.

PubMed

Brink, James A; Arenson, Ronald L; Grist, Thomas M; Lewin, Jonathan S; Enzmann, Dieter

2017-09-01

Advances in informatics and information technology are sure to alter the practice of medical imaging and image-guided therapies substantially over the next decade. Each element of the imaging continuum will be affected by substantial increases in computing capacity coincident with the seamless integration of digital technology into our society at large. This article focuses primarily on areas where this IT transformation is likely to have a profound effect on the practice of radiology. • Clinical decision support ensures consistent and appropriate resource utilization. • Big data enables correlation of health information across multiple domains. • Data mining advances the quality of medical decision-making. • Business analytics allow radiologists to maximize the benefits of imaging resources.

Deep Learning Nuclei Detection in Digitized Histology Images by Superpixels

PubMed Central

Sornapudi, Sudhir; Stanley, Ronald Joe; Stoecker, William V.; Almubarak, Haidar; Long, Rodney; Antani, Sameer; Thoma, George; Zuna, Rosemary; Frazier, Shelliane R.

2018-01-01

Background: Advances in image analysis and computational techniques have facilitated automatic detection of critical features in histopathology images. Detection of nuclei is critical for squamous epithelium cervical intraepithelial neoplasia (CIN) classification into normal, CIN1, CIN2, and CIN3 grades. Methods: In this study, a deep learning (DL)-based nuclei segmentation approach is investigated based on gathering localized information through the generation of superpixels using a simple linear iterative clustering algorithm and training with a convolutional neural network. Results: The proposed approach was evaluated on a dataset of 133 digitized histology images and achieved an overall nuclei detection (object-based) accuracy of 95.97%, with demonstrated improvement over imaging-based and clustering-based benchmark techniques. Conclusions: The proposed DL-based nuclei segmentation Method with superpixel analysis has shown improved segmentation results in comparison to state-of-the-art methods. PMID:29619277

Medical ultrasound - From inner space to outer space

NASA Technical Reports Server (NTRS)

Rooney, J. A.

1984-01-01

During the last decade, medical ultrasound has rapidly become a widely accepted imaging modality used in many medical specialties. It has the advantages that it is noninvasive, does not use ionizing radiation, is relatively inexpensive and is easy to use. Future trends in ultrasound include expanded areas of use, advanced signal processing and digital image analysis including tissue characterization and three-dimensional reconstructions.

Processing and analysis of commercial satellite image data of the nuclear accident near Chernobyl, U.S.S.R.

USGS Publications Warehouse

Sadowski, Franklin G.; Covington, Steven J.

1987-01-01

Advanced digital processing techniques were applied to Landsat-5 Thematic Mapper (TM) data and SPOT highresolution visible (HRV) panchromatic data to maximize the utility of images of a nuclear powerplant emergency at Chernobyl in the Soviet Ukraine. The images demonstrate the unique interpretive capabilities provided by the numerous spectral bands of the Thematic Mapper and the high spatial resolution of the SPOT HRV sensor.

Projection display technologies for the new millennium

NASA Astrophysics Data System (ADS)

Kahn, Frederic J.

2000-04-01

Although analog CRTs continue to enable most of the world's electronic projection displays such as US consumer rear projection televisions, discrete pixel (digital) active matrix LCD and DLP reflective mirror array projectors have rapidly created large nonconsumer markets--primarily for business. Recent advances in image quality, compactness and cost effectiveness of digital projectors have the potential to revolutionize major consumer and entertainment markets as well. Digital penetration of the mainstream consumer projection TV market will begin in the hear 2000. By 2005 digital projection HDTVs could take the major share of the consumer HDTV projection market. Digital projection is expected to dominate both the consumer HDTV and the cinema market by 2010, resulting in potential shipments for all projection markets exceeding 10 M units per year. Digital projection is improving at a rate 10X faster than analog CRT projectors and 5X faster than PDP flat panels. Continued rapid improvement of digital projection is expected due to its relative immaturity and due to the wide diversity of technological improvements being pursued. Key technology enablers are the imaging panels, light sources and micro-optics. Market shares of single panel projectors, MEMs panels, LCOS panels and low T p-Si TFT LCD panel variants are expected to increase.

Advanced image based methods for structural integrity monitoring: Review and prospects

NASA Astrophysics Data System (ADS)

Farahani, Behzad V.; Sousa, Pedro José; Barros, Francisco; Tavares, Paulo J.; Moreira, Pedro M. G. P.

2018-02-01

There is a growing trend in engineering to develop methods for structural integrity monitoring and characterization of in-service mechanical behaviour of components. The fast growth in recent years of image processing techniques and image-based sensing for experimental mechanics, brought about a paradigm change in phenomena sensing. Hence, several widely applicable optical approaches are playing a significant role in support of experiment. The current review manuscript describes advanced image based methods for structural integrity monitoring, and focuses on methods such as Digital Image Correlation (DIC), Thermoelastic Stress Analysis (TSA), Electronic Speckle Pattern Interferometry (ESPI) and Speckle Pattern Shearing Interferometry (Shearography). These non-contact full-field techniques rely on intensive image processing methods to measure mechanical behaviour, and evolve even as reviews such as this are being written, which justifies a special effort to keep abreast of this progress.

[Detection of lung nodules. New opportunities in chest radiography].

PubMed

Pötter-Lang, S; Schalekamp, S; Schaefer-Prokop, C; Uffmann, M

2014-05-01

Chest radiography still represents the most commonly performed X-ray examination because it is readily available, requires low radiation doses and is relatively inexpensive. However, as previously published, many initially undetected lung nodules are retrospectively visible in chest radiographs. The great improvements in detector technology with the increasing dose efficiency and improved contrast resolution provide a better image quality and reduced dose needs. The dual energy acquisition technique and advanced image processing methods (e.g. digital bone subtraction and temporal subtraction) reduce the anatomical background noise by reduction of overlapping structures in chest radiography. Computer-aided detection (CAD) schemes increase the awareness of radiologists for suspicious areas. The advanced image processing methods show clear improvements for the detection of pulmonary lung nodules in chest radiography and strengthen the role of this method in comparison to 3D acquisition techniques, such as computed tomography (CT). Many of these methods will probably be integrated into standard clinical treatment in the near future. Digital software solutions offer advantages as they can be easily incorporated into radiology departments and are often more affordable as compared to hardware solutions.

Mathematical modeling and SAR simulation multifunction SAR technology efforts

NASA Technical Reports Server (NTRS)

Griffin, C. R.; Estes, J. M.

1981-01-01

The orbital SAR (synthetic aperture radar) simulation data was used in several simulation efforts directed toward advanced SAR development. Efforts toward simulating an operational radar, simulation of antenna polarization effects, and simulation of SAR images at serveral different wavelengths are discussed. Avenues for improvements in the orbital SAR simulation and its application to the development of advanced digital radar data processing schemes are indicated.

Implementation of large-scale routine diagnostics using whole slide imaging in Sweden: Digital pathology experiences 2006-2013

PubMed Central

Thorstenson, Sten; Molin, Jesper; Lundström, Claes

2014-01-01

Recent technological advances have improved the whole slide imaging (WSI) scanner quality and reduced the cost of storage, thereby enabling the deployment of digital pathology for routine diagnostics. In this paper we present the experiences from two Swedish sites having deployed routine large-scale WSI for primary review. At Kalmar County Hospital, the digitization process started in 2006 to reduce the time spent at the microscope in order to improve the ergonomics. Since 2008, more than 500,000 glass slides have been scanned in the routine operations of Kalmar and the neighboring Linköping University Hospital. All glass slides are digitally scanned yet they are also physically delivered to the consulting pathologist who can choose to review the slides on screen, in the microscope, or both. The digital operations include regular remote case reporting by a few hospital pathologists, as well as around 150 cases per week where primary review is outsourced to a private clinic. To investigate how the pathologists choose to use the digital slides, a web-based questionnaire was designed and sent out to the pathologists in Kalmar and Linköping. The responses showed that almost all pathologists think that ergonomics have improved and that image quality was sufficient for most histopathologic diagnostic work. 38 ± 28% of the cases were diagnosed digitally, but the survey also revealed that the pathologists commonly switch back and forth between digital and conventional microscopy within the same case. The fact that two full-scale digital systems have been implemented and that a large portion of the primary reporting is voluntarily performed digitally shows that large-scale digitization is possible today. PMID:24843825

A flexible and accurate digital volume correlation method applicable to high-resolution volumetric images

NASA Astrophysics Data System (ADS)

Pan, Bing; Wang, Bo

2017-10-01

Digital volume correlation (DVC) is a powerful technique for quantifying interior deformation within solid opaque materials and biological tissues. In the last two decades, great efforts have been made to improve the accuracy and efficiency of the DVC algorithm. However, there is still a lack of a flexible, robust and accurate version that can be efficiently implemented in personal computers with limited RAM. This paper proposes an advanced DVC method that can realize accurate full-field internal deformation measurement applicable to high-resolution volume images with up to billions of voxels. Specifically, a novel layer-wise reliability-guided displacement tracking strategy combined with dynamic data management is presented to guide the DVC computation from slice to slice. The displacements at specified calculation points in each layer are computed using the advanced 3D inverse-compositional Gauss-Newton algorithm with the complete initial guess of the deformation vector accurately predicted from the computed calculation points. Since only limited slices of interest in the reference and deformed volume images rather than the whole volume images are required, the DVC calculation can thus be efficiently implemented on personal computers. The flexibility, accuracy and efficiency of the presented DVC approach are demonstrated by analyzing computer-simulated and experimentally obtained high-resolution volume images.

Scleral Lens Clearance Assessment with Biomicroscopy and Anterior Segment Optical Coherence Tomography.

PubMed

Yeung, Debby; Sorbara, Luigina

2018-01-01

It is important to be able to accurately estimate the central corneal clearance when fitting scleral contact lenses. Tools available have intrinsic biases due to the angle of viewing, and therefore an idea of the amount of error in estimation will benefit the fitter. To compare the accuracy of observers' ability to estimate scleral contact lens central corneal clearance (CCC) with biomicroscopy to measurements using slit-lamp imaging and anterior segment optical coherence tomography (AS-OCT). In a Web-based survey with images of four scleral lens fits obtained with a slit-lamp video imaging system, participants were asked to estimate the CCC. Responses were compared with known values of CCC of these images determined with an image-processing program (digital CCC) and using the AS-OCT (AS-OCT CCC). Bland-Altman plots and concordance correlation coefficients were used to assess the agreement of CCC measured by the various methods. Sixty-six participants were categorized for analysis based on the amount of experience with scleral lens fitting into novice, intermediate, or advanced fitters. Comparing the estimated CCC to the digital CCC, all three groups overestimated by an average of +27.3 ± 67.3 μm. The estimated CCC was highly correlated to the digital CCC (0.79, 0.92, and 0.94 for each group, respectively). Compared with the CCC measurements using AS-OCT, the three groups of participants overestimated by +103.3 μm and had high correlations (0.79, 0.93, and 0.94 for each group). Results from this study validate the ability of contact lens practitioners to observe and estimate the CCC in scleral lens fittings through the use of biomicroscopic viewing. Increasing experience with scleral lens fitting does not improve the correlation with measured CCC from digital or the AS-OCT. However, the intermediate and advanced groups display significantly less inter-observer variability compared with the novice group.

Optical design and development of a snapshot light-field laryngoscope

NASA Astrophysics Data System (ADS)

Zhu, Shuaishuai; Jin, Peng; Liang, Rongguang; Gao, Liang

2018-02-01

The convergence of recent advances in optical fabrication and digital processing yields a generation of imaging technology-light-field (LF) cameras which bridge the realms of applied mathematics, optics, and high-performance computing. Herein for the first time, we introduce the paradigm of LF imaging into laryngoscopy. The resultant probe can image the three-dimensional shape of vocal folds within a single camera exposure. Furthermore, to improve the spatial resolution, we developed an image fusion algorithm, providing a simple solution to a long-standing problem in LF imaging.

[Ethical reflection on multidisciplinarity and confidentiality of information in medical imaging through new information and communication technologies].

PubMed

Béranger, J; Le Coz, P

2012-05-01

Technological advances in medical imaging has resulted in the exponential increase of the number of images per examination, caused the irreversible decline of the silver film and imposed digital imaging. This digitization is a concept whose levels of development are multiple, reflecting the complexity of this process of technological change. Under these conditions, the use of medical information via new information and communication technologies is at the crossroads of several scientific approaches and several disciplines (medicine, ethics, law, economics, psychology, etc.) surrounding the information systems in health, doctor-patient relationship and concepts that are associated. Each day, these new information and communication technologies open up new horizons and the space of possibilities, spectacularly developing access to information and knowledge. In this perspective of digital technology emergence impacting the multidisciplinary use of health information systems, the ethical questions are numerous, especially on the preservation of privacy, confidentiality and security of medical data, and their accessibility and integrity. Copyright © 2012 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

Complementary concept for an image archive and communication system in a cardiological department based on CD-medical, an online archive, and networking facilities

NASA Astrophysics Data System (ADS)

Oswald, Helmut; Mueller-Jones, Kay; Builtjes, Jan; Fleck, Eckart

1998-07-01

The developments in information technologies -- computer hardware, networking and storage media -- has led to expectations that these advances make it possible to replace 35 mm film completely by digital techniques in the catheter laboratory. Besides the role of an archival medium, cine film is used as the major image review and exchange medium in cardiology. None of the today technologies can fulfill completely the requirements to replace cine film. One of the major drawbacks of cine film is the single access in time and location. For the four catheter laboratories in our institutions we have designed a complementary concept combining the CD-R, also called CD-medical, as a single patient storage and exchange medium, and a digital archive for on-line access and image review of selected frames or short sequences on adequate medical workstations. The image data from various modalities as well as all digital documents regarding to a patient are part of an electronic patient record. The access, the processing and the display of documents is supported by an integrated medical application.

An earth imaging camera simulation using wide-scale construction of reflectance surfaces

NASA Astrophysics Data System (ADS)

Murthy, Kiran; Chau, Alexandra H.; Amin, Minesh B.; Robinson, M. Dirk

2013-10-01

Developing and testing advanced ground-based image processing systems for earth-observing remote sensing applications presents a unique challenge that requires advanced imagery simulation capabilities. This paper presents an earth-imaging multispectral framing camera simulation system called PayloadSim (PaySim) capable of generating terabytes of photorealistic simulated imagery. PaySim leverages previous work in 3-D scene-based image simulation, adding a novel method for automatically and efficiently constructing 3-D reflectance scenes by draping tiled orthorectified imagery over a geo-registered Digital Elevation Map (DEM). PaySim's modeling chain is presented in detail, with emphasis given to the techniques used to achieve computational efficiency. These techniques as well as cluster deployment of the simulator have enabled tuning and robust testing of image processing algorithms, and production of realistic sample data for customer-driven image product development. Examples of simulated imagery of Skybox's first imaging satellite are shown.

Improving HCAHPS Scores with Advances in Digital Radiography.

PubMed

Matthews, Marianne; Cretella, Gregg; Nicholas, William

2016-01-01

The imaging department can be instrumental in contributing to a healthcare facility's ability to succeed in this new era of competition. Advances in DR technology can improve patient perceptions in the imaging department by improving efficiencies and outcomes which, in turn, can ultimately bolster overall HCAHPS scores. Specific areas for improved scores by utilization of DR include nurse communication, doctor communication, pain management, and communication about medication. Value based purchasing brought with it a mandate for hospitals to track key metrics, which requires an investment in time, tools, and human resources. However, this mandate also presents hospitals and imaging departments, with an opportunity to leverage those very metrics to better market their facilities.

Digital pathology and image analysis for robust high-throughput quantitative assessment of Alzheimer disease neuropathologic changes.

PubMed

Neltner, Janna Hackett; Abner, Erin Lynn; Schmitt, Frederick A; Denison, Stephanie Kay; Anderson, Sonya; Patel, Ela; Nelson, Peter T

2012-12-01

Quantitative neuropathologic methods provide information that is important for both research and clinical applications. The technologic advancement of digital pathology and image analysis offers new solutions to enable valid quantification of pathologic severity that is reproducible between raters regardless of experience. Using an Aperio ScanScope XT and its accompanying image analysis software, we designed algorithms for quantitation of amyloid and tau pathologies on 65 β-amyloid (6F/3D antibody) and 48 phospho-tau (PHF-1)-immunostained sections of human temporal neocortex. Quantitative digital pathologic data were compared with manual pathology counts. There were excellent correlations between manually counted and digitally analyzed neuropathologic parameters (R² = 0.56-0.72). Data were highly reproducible among 3 participants with varying degrees of expertise in neuropathology (intraclass correlation coefficient values, >0.910). Digital quantification also provided additional parameters, including average plaque area, which shows statistically significant differences when samples are stratified according to apolipoprotein E allele status (average plaque area, 380.9 μm² in apolipoprotein E [Latin Small Letter Open E]4 carriers vs 274.4 μm² for noncarriers; p < 0.001). Thus, digital pathology offers a rigorous and reproducible method for quantifying Alzheimer disease neuropathologic changes and may provide additional insights into morphologic characteristics that were previously more challenging to assess because of technical limitations.

Image Montaging for Creating a Virtual Pathology Slide: An Innovative and Economical Tool to Obtain a Whole Slide Image

PubMed Central

Pandurangappa, Rohit; Annavajjula, Saileela; Rajashekaraiah, Premalatha Bidadi

2016-01-01

Background. Microscopes are omnipresent throughout the field of biological research. With microscopes one can see in detail what is going on at the cellular level in tissues. Though it is a ubiquitous tool, the limitation is that with high magnification there is a small field of view. It is often advantageous to see an entire sample at high magnification. Over the years technological advancements in optics have helped to provide solutions to this limitation of microscopes by creating the so-called dedicated “slide scanners” which can provide a “whole slide digital image.” These scanners can provide seamless, large-field-of-view, high resolution image of entire tissue section. The only disadvantage of such complete slide imaging system is its outrageous cost, thereby hindering their practical use by most laboratories, especially in developing and low resource countries. Methods. In a quest for their substitute, we tried commonly used image editing software Adobe Photoshop along with a basic image capturing device attached to a trinocular microscope to create a digital pathology slide. Results. The seamless image created using Adobe Photoshop maintained its diagnostic quality. Conclusion. With time and effort photomicrographs obtained from a basic camera-microscope set up can be combined and merged in Adobe Photoshop to create a whole slide digital image of practically usable quality at a negligible cost. PMID:27747147

Image Montaging for Creating a Virtual Pathology Slide: An Innovative and Economical Tool to Obtain a Whole Slide Image.

PubMed

Banavar, Spoorthi Ravi; Chippagiri, Prashanthi; Pandurangappa, Rohit; Annavajjula, Saileela; Rajashekaraiah, Premalatha Bidadi

2016-01-01

Background . Microscopes are omnipresent throughout the field of biological research. With microscopes one can see in detail what is going on at the cellular level in tissues. Though it is a ubiquitous tool, the limitation is that with high magnification there is a small field of view. It is often advantageous to see an entire sample at high magnification. Over the years technological advancements in optics have helped to provide solutions to this limitation of microscopes by creating the so-called dedicated "slide scanners" which can provide a "whole slide digital image." These scanners can provide seamless, large-field-of-view, high resolution image of entire tissue section. The only disadvantage of such complete slide imaging system is its outrageous cost, thereby hindering their practical use by most laboratories, especially in developing and low resource countries. Methods . In a quest for their substitute, we tried commonly used image editing software Adobe Photoshop along with a basic image capturing device attached to a trinocular microscope to create a digital pathology slide. Results . The seamless image created using Adobe Photoshop maintained its diagnostic quality. Conclusion . With time and effort photomicrographs obtained from a basic camera-microscope set up can be combined and merged in Adobe Photoshop to create a whole slide digital image of practically usable quality at a negligible cost.

Technical advances of interventional fluoroscopy and flat panel image receptor.

PubMed

Lin, Pei-Jan Paul

2008-11-01

In the past decade, various radiation reducing devices and control circuits have been implemented on fluoroscopic imaging equipment. Because of the potential for lengthy fluoroscopic procedures in interventional cardiovascular angiography, these devices and control circuits have been developed for the cardiac catheterization laboratories and interventional angiography suites. Additionally, fluoroscopic systems equipped with image intensifiers have benefited from technological advances in x-ray tube, x-ray generator, and spectral shaping filter technologies. The high heat capacity x-ray tube, the medium frequency inverter generator with high performance switching capability, and the patient dose reduction spectral shaping filter had already been implemented on the image intensified fluoroscopy systems. These three underlying technologies together with the automatic dose rate and image quality (ADRIQ) control logic allow patients undergoing cardiovascular angiography procedures to benefit from "lower patient dose" with "high image quality." While photoconductor (or phosphor plate) x-ray detectors and signal capture thin film transistor (TFT) and charge coupled device (CCD) arrays are analog in nature, the advent of the flat panel image receptor allowed for fluoroscopy procedures to become more streamlined. With the analog-to-digital converter built into the data lines, the flat panel image receptor appears to become a digital device. While the transition from image intensified fluoroscopy systems to flat panel image receptor fluoroscopy systems is part of the on-going "digitization of imaging," the value of a flat panel image receptor may have to be evaluated with respect to patient dose, image quality, and clinical application capabilities. The advantage of flat panel image receptors has yet to be fully explored. For instance, the flat panel image receptor has its disadvantages as compared to the image intensifiers; the cost of the equipment is probably the most obvious. On the other hand, due to its wide dynamic range and linearity, lowering of patient dose beyond current practice could be achieved through the calibration process of the flat panel input dose rate being set to, for example, one half or less of current values. In this article various radiation saving devices and control circuits are briefly described. This includes various types of fluoroscopic systems designed to strive for reduction of patient exposure with the application of spectral shaping filters. The main thrust is to understand the ADRIQ control logic, through equipment testing, as it relates to clinical applications, and to show how this ADRIQ control logic "ties" those three technological advancements together to provide low radiation dose to the patient with high quality fluoroscopic images. Finally, rotational angiography with computed tomography (CT) and three dimensional (3-D) images utilizing flat panel technology will be reviewed as they pertain to diagnostic imaging in cardiovascular disease.

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers.

PubMed

Cui, Yang; Hanley, Luke

2015-06-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science.

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers

PubMed Central

Cui, Yang; Hanley, Luke

2015-01-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science. PMID:26133872

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers

NASA Astrophysics Data System (ADS)

Cui, Yang; Hanley, Luke

2015-06-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science.

Large-Scale Quantitative Analysis of Painting Arts

PubMed Central

Kim, Daniel; Son, Seung-Woo; Jeong, Hawoong

2014-01-01

Scientists have made efforts to understand the beauty of painting art in their own languages. As digital image acquisition of painting arts has made rapid progress, researchers have come to a point where it is possible to perform statistical analysis of a large-scale database of artistic paints to make a bridge between art and science. Using digital image processing techniques, we investigate three quantitative measures of images – the usage of individual colors, the variety of colors, and the roughness of the brightness. We found a difference in color usage between classical paintings and photographs, and a significantly low color variety of the medieval period. Interestingly, moreover, the increment of roughness exponent as painting techniques such as chiaroscuro and sfumato have advanced is consistent with historical circumstances. PMID:25501877

Fast and accurate automated cell boundary determination for fluorescence microscopy

NASA Astrophysics Data System (ADS)

Arce, Stephen Hugo; Wu, Pei-Hsun; Tseng, Yiider

2013-07-01

Detailed measurement of cell phenotype information from digital fluorescence images has the potential to greatly advance biomedicine in various disciplines such as patient diagnostics or drug screening. Yet, the complexity of cell conformations presents a major barrier preventing effective determination of cell boundaries, and introduces measurement error that propagates throughout subsequent assessment of cellular parameters and statistical analysis. State-of-the-art image segmentation techniques that require user-interaction, prolonged computation time and specialized training cannot adequately provide the support for high content platforms, which often sacrifice resolution to foster the speedy collection of massive amounts of cellular data. This work introduces a strategy that allows us to rapidly obtain accurate cell boundaries from digital fluorescent images in an automated format. Hence, this new method has broad applicability to promote biotechnology.

Integration of USB and firewire cameras in machine vision applications

NASA Astrophysics Data System (ADS)

Smith, Timothy E.; Britton, Douglas F.; Daley, Wayne D.; Carey, Richard

1999-08-01

Digital cameras have been around for many years, but a new breed of consumer market cameras is hitting the main stream. By using these devices, system designers and integrators will be well posited to take advantage of technological advances developed to support multimedia and imaging applications on the PC platform. Having these new cameras on the consumer market means lower cost, but it does not necessarily guarantee ease of integration. There are many issues that need to be accounted for like image quality, maintainable frame rates, image size and resolution, supported operating system, and ease of software integration. This paper will describe briefly a couple of the consumer digital standards, and then discuss some of the advantages and pitfalls of integrating both USB and Firewire cameras into computer/machine vision applications.

From the sample preparation to the volume rendering images of small animals: A step by step example of a procedure to carry out the micro-CT study of the leafhopper insect Homalodisca vitripennis (Hemiptera: Cicadellidae)

USDA-ARS?s Scientific Manuscript database

Advances in micro-CT, digital computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside of the body. Combining micro-CT with Digital Video Library systems, and linking this to Big Data, will change the way researchers, entomologist, and the public search and use anato...

Voss at ADVASC Growth Chamber in Destiny module

NASA Image and Video Library

2001-05-22

ISS002-E-6300 (22 May 2001) --- James S. Voss, Expedition Two flight engineer, works with the Advanced Astro Culture (ADVASC) Condensate Fluid Syringe at the ADVASC Growth Chamber in the U.S. Laboratory. The image was taken with a digital still camera.

A computational image analysis glossary for biologists.

PubMed

Roeder, Adrienne H K; Cunha, Alexandre; Burl, Michael C; Meyerowitz, Elliot M

2012-09-01

Recent advances in biological imaging have resulted in an explosion in the quality and quantity of images obtained in a digital format. Developmental biologists are increasingly acquiring beautiful and complex images, thus creating vast image datasets. In the past, patterns in image data have been detected by the human eye. Larger datasets, however, necessitate high-throughput objective analysis tools to computationally extract quantitative information from the images. These tools have been developed in collaborations between biologists, computer scientists, mathematicians and physicists. In this Primer we present a glossary of image analysis terms to aid biologists and briefly discuss the importance of robust image analysis in developmental studies.

The 3D scanner prototype utilize object profile imaging using line laser and octave software

NASA Astrophysics Data System (ADS)

Nurdini, Mugi; Manunggal, Trikarsa Tirtadwipa; Samsi, Agus

2016-11-01

Three-dimensional scanner or 3D Scanner is a device to reconstruct the real object into digital form on a computer. 3D Scanner is a technology that is being developed, especially in developed countries, where the current 3D Scanner devices is the advanced version with a very expensive prices. This study is basically a simple prototype of 3D Scanner with a very low investment costs. 3D Scanner prototype device consists of a webcam, a rotating desk system controlled by a stepper motor and Arduino UNO, and a line laser. Objects that limit the research is the object with same radius from its center point (object pivot). Scanning is performed by using object profile imaging by line laser which is then captured by the camera and processed by a computer (image processing) using Octave software. On each image acquisition, the scanned object on a rotating desk rotated by a certain degree, so for one full turn multiple images of a number of existing side are finally obtained. Then, the profile of the entire images is extracted in order to obtain digital object dimension. Digital dimension is calibrated by length standard, called gage block. Overall dimensions are then digitally reconstructed into a three-dimensional object. Validation of the scanned object reconstruction of the original object dimensions expressed as a percentage error. Based on the results of data validation, horizontal dimension error is about 5% to 23% and vertical dimension error is about +/- 3%.

Integrating research and clinical neuroimaging for the evaluation of traumatic brain injury recovery

NASA Astrophysics Data System (ADS)

Senseney, Justin; Ollinger, John; Graner, John; Lui, Wei; Oakes, Terry; Riedy, Gerard

2015-03-01

Advanced MRI research and other imaging modalities may serve as biomarkers for the evaluation of traumatic brain injury (TBI) recovery. However, these advanced modalities typically require off-line processing which creates images that are incompatible with radiologist viewing software sold commercially. AGFA Impax is an example of such a picture archiving and communication system(PACS) that is used by many radiology departments in the United States Military Health System. By taking advantage of Impax's use of the Digital Imaging and Communications in Medicine (DICOM) standard, we developed a system that allows for advanced medical imaging to be incorporated into clinical PACS. Radiology research can now be conducted using existing clinical imaging display platforms resources in combination with image processingtechniques that are only available outside of the clinical scanning environment. We extracted the spatial and identification elements of theDICOM standard that are necessary to allow research images to be incorporatedinto a clinical radiology system, and developed a tool that annotates research images with the proper tags. This allows for the evaluation of imaging representations of biological markers that may be useful in theevaluation of TBI and TBI recovery.

Next-generation digital camera integration and software development issues

NASA Astrophysics Data System (ADS)

Venkataraman, Shyam; Peters, Ken; Hecht, Richard

1998-04-01

This paper investigates the complexities associated with the development of next generation digital cameras due to requirements in connectivity and interoperability. Each successive generation of digital camera improves drastically in cost, performance, resolution, image quality and interoperability features. This is being accomplished by advancements in a number of areas: research, silicon, standards, etc. As the capabilities of these cameras increase, so do the requirements for both hardware and software. Today, there are two single chip camera solutions in the market including the Motorola MPC 823 and LSI DCAM- 101. Real time constraints for a digital camera may be defined by the maximum time allowable between capture of images. Constraints in the design of an embedded digital camera include processor architecture, memory, processing speed and the real-time operating systems. This paper will present the LSI DCAM-101, a single-chip digital camera solution. It will present an overview of the architecture and the challenges in hardware and software for supporting streaming video in such a complex device. Issues presented include the development of the data flow software architecture, testing and integration on this complex silicon device. The strategy for optimizing performance on the architecture will also be presented.

Digital Rocks Portal: a sustainable platform for imaged dataset sharing, translation and automated analysis

NASA Astrophysics Data System (ADS)

Prodanovic, M.; Esteva, M.; Hanlon, M.; Nanda, G.; Agarwal, P.

2015-12-01

Recent advances in imaging have provided a wealth of 3D datasets that reveal pore space microstructure (nm to cm length scale) and allow investigation of nonlinear flow and mechanical phenomena from first principles using numerical approaches. This framework has popularly been called "digital rock physics". Researchers, however, have trouble storing and sharing the datasets both due to their size and the lack of standardized image types and associated metadata for volumetric datasets. This impedes scientific cross-validation of the numerical approaches that characterize large scale porous media properties, as well as development of multiscale approaches required for correct upscaling. A single research group typically specializes in an imaging modality and/or related modeling on a single length scale, and lack of data-sharing infrastructure makes it difficult to integrate different length scales. We developed a sustainable, open and easy-to-use repository called the Digital Rocks Portal, that (1) organizes images and related experimental measurements of different porous materials, (2) improves access to them for a wider community of geosciences or engineering researchers not necessarily trained in computer science or data analysis. Once widely accepter, the repository will jumpstart productivity and enable scientific inquiry and engineering decisions founded on a data-driven basis. This is the first repository of its kind. We show initial results on incorporating essential software tools and pipelines that make it easier for researchers to store and reuse data, and for educators to quickly visualize and illustrate concepts to a wide audience. For data sustainability and continuous access, the portal is implemented within the reliable, 24/7 maintained High Performance Computing Infrastructure supported by the Texas Advanced Computing Center (TACC) at the University of Texas at Austin. Long-term storage is provided through the University of Texas System Research Cyber-infrastructure initiative.

3D Printing and Digital Rock Physics for Geomaterials

NASA Astrophysics Data System (ADS)

Martinez, M. J.; Yoon, H.; Dewers, T. A.

2015-12-01

Imaging techniques for the analysis of porous structures have revolutionized our ability to quantitatively characterize geomaterials. Digital representations of rock from CT images and physics modeling based on these pore structures provide the opportunity to further advance our quantitative understanding of fluid flow, geomechanics, and geochemistry, and the emergence of coupled behaviors. Additive manufacturing, commonly known as 3D printing, has revolutionized production of custom parts with complex internal geometries. For the geosciences, recent advances in 3D printing technology may be co-opted to print reproducible porous structures derived from CT-imaging of actual rocks for experimental testing. The use of 3D printed microstructure allows us to surmount typical problems associated with sample-to-sample heterogeneity that plague rock physics testing and to test material response independent from pore-structure variability. Together, imaging, digital rocks and 3D printing potentially enables a new workflow for understanding coupled geophysical processes in a real, but well-defined setting circumventing typical issues associated with reproducibility, enabling full characterization and thus connection of physical phenomena to structure. In this talk we will discuss the possibilities that these technologies can bring to geosciences and present early experiences with coupled multiscale experimental and numerical analysis using 3D printed fractured rock specimens. In particular, we discuss the processes of selection and printing of transparent fractured specimens based on 3D reconstruction of micro-fractured rock to study fluid flow characterization and manipulation. Micro-particle image velocimetry is used to directly visualize 3D single and multiphase flow velocity in 3D fracture networks. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

X-ray imaging with amorphous silicon active matrix flat-panel imagers (AMFPIs)

NASA Astrophysics Data System (ADS)

El-Mohri, Youcef; Antonuk, Larry E.; Jee, Kyung-Wook; Maolinbay, Manat; Rong, Xiujiang; Siewerdsen, Jeffrey H.; Verma, Manav; Zhao, Qihua

1997-07-01

Recent advances in thin-film electronics technology have opened the way for the use of flat-panel imagers in a number of medical imaging applications. These novel imagers offer real time digital readout capabilities (˜30 frames per second), radiation hardness (>106cGy), large area (30×40 cm2) and compactness (˜1 cm). Such qualities make them strong candidates for the replacement of conventional x-ray imaging technologies such as film-screen and image intensifier systems. In this report, qualities and potential of amorphous silicon based active matrix flat-panel imagers are outlined for various applications such as radiation therapy, radiography, fluoroscopy and mammography.

Measurement Sets and Sites Commonly Used for High Spatial Resolution Image Product Characterization

NASA Technical Reports Server (NTRS)

Pagnutti, Mary

2006-01-01

Scientists within NASA's Applied Sciences Directorate have developed a well-characterized remote sensing Verification & Validation (V&V) site at the John C. Stennis Space Center (SSC). This site has enabled the in-flight characterization of satellite high spatial resolution remote sensing system products form Space Imaging IKONOS, Digital Globe QuickBird, and ORBIMAGE OrbView, as well as advanced multispectral airborne digital camera products. SSC utilizes engineered geodetic targets, edge targets, radiometric tarps, atmospheric monitoring equipment and their Instrument Validation Laboratory to characterize high spatial resolution remote sensing data products. This presentation describes the SSC characterization capabilities and techniques in the visible through near infrared spectrum and examples of calibration results.

Advanced Optical Technologies for Defense Trauma and Critical Care

DTIC Science & Technology

2014-02-04

conventional LSI. We also demonstrated that mcLSI enables improved characterization of curved surfaces of the body by positioning LSI modules at...Implementation of an LED based clinical spatial frequency domain imaging 17 system. Proc SPIE Vol. 8254, Emerging Digital Micromirror Device Based

Reconstituted Three-Dimensional Interactive Imaging

NASA Technical Reports Server (NTRS)

Hamilton, Joseph; Foley, Theodore; Duncavage, Thomas; Mayes, Terrence

2010-01-01

A method combines two-dimensional images, enhancing the images as well as rendering a 3D, enhanced, interactive computer image or visual model. Any advanced compiler can be used in conjunction with any graphics library package for this method, which is intended to take digitized images and virtually stack them so that they can be interactively viewed as a set of slices. This innovation can take multiple image sources (film or digital) and create a "transparent" image with higher densities in the image being less transparent. The images are then stacked such that an apparent 3D object is created in virtual space for interactive review of the set of images. This innovation can be used with any application where 3D images are taken as slices of a larger object. These could include machines, materials for inspection, geological objects, or human scanning. Illuminous values were stacked into planes with different transparency levels of tissues. These transparency levels can use multiple energy levels, such as density of CT scans or radioactive density. A desktop computer with enough video memory to produce the image is capable of this work. The memory changes with the size and resolution of the desired images to be stacked and viewed.

Imaging of the peripheral retina

PubMed Central

Kernt, Marcus; Kampik, Anselm

2013-01-01

The technical progress of the recent years has revolutionized imaging in ophthalmology. Scanning laser ophthalmoscopy (SLO), digital angiography, optical coherence tomography (OCT), and detection of fundus autofluorescence (FAF) have fundamentally changed our understanding of numerous retinal and choroidal diseases. Besides the tremendous advances in macular diagnostics, there is more and more evidence that central pathologies are often directly linked to changes in the peripheral retina. This review provides a brief overview on current posterior segment imaging techniques with a special focus on the peripheral retina. PMID:24391370

EOS image data processing system definition study

NASA Technical Reports Server (NTRS)

Gilbert, J.; Honikman, T.; Mcmahon, E.; Miller, E.; Pietrzak, L.; Yorsz, W.

1973-01-01

The Image Processing System (IPS) requirements and configuration are defined for NASA-sponsored advanced technology Earth Observatory System (EOS). The scope included investigation and definition of IPS operational, functional, and product requirements considering overall system constraints and interfaces (sensor, etc.) The scope also included investigation of the technical feasibility and definition of a point design reflecting system requirements. The design phase required a survey of present and projected technology related to general and special-purpose processors, high-density digital tape recorders, and image recorders.

Advanced Prosthetic Gait Training Tool

DTIC Science & Technology

2015-12-01

motion capture sequences was provided by MPL to CCAD and OGAL. CCAD’s work focused on imposing these sequences on the SantosTM digital human avatar ...manipulating the avatar image. These manipulations are accomplished in the context of reinforcing what is the more ideal position and relating...focus on the visual environment by asking users to manipulate a static image of the Santos avatar to represent their perception of what they observe

The Bushbaby Optic Nerve: Fiber Count and Fiber Diameter Spectrum

DTIC Science & Technology

1986-03-01

laminar organization of rece,)tive field properties in the lateral geniculate nucleus of bushbaby (Norton and Casagrande, 1982), the organization of...field properties in lateral geniculate nucleus of bushbaby (Galago cras- sicaudatus). Journal of Neurophysiology. 47(4):715-741. O’Fiaherty, J.J...employed an advanced digitized image analysis system (Carl Zeiss Inc., Videoplan Image Analysis System)* to more accurately and rapidly collect, analyze, and

Digital tool for detecting diabetic retinopathy in retinography image using gabor transform

NASA Astrophysics Data System (ADS)

Morales, Y.; Nuñez, R.; Suarez, J.; Torres, C.

2017-01-01

Diabetic retinopathy is a chronic disease and is the leading cause of blindness in the population. The fundamental problem is that diabetic retinopathy is usually asymptomatic in its early stage and, in advanced stages, it becomes incurable, hence the importance of early detection. To detect diabetic retinopathy, the ophthalmologist examines the fundus by ophthalmoscopy, after sends the patient to get a Retinography. Sometimes, these retinography are not of good quality. This paper show the implementation of a digital tool that facilitates to ophthalmologist provide better patient diagnosis suffering from diabetic retinopathy, informing them that type of retinopathy has and to what degree of severity is find . This tool develops an algorithm in Matlab based on Gabor transform and in the application of digital filters to provide better and higher quality of retinography. The performance of algorithm has been compared with conventional methods obtaining resulting filtered images with better contrast and higher.

High resolution image processing on low-cost microcomputers

NASA Technical Reports Server (NTRS)

Miller, R. L.

1993-01-01

Recent advances in microcomputer technology have resulted in systems that rival the speed, storage, and display capabilities of traditionally larger machines. Low-cost microcomputers can provide a powerful environment for image processing. A new software program which offers sophisticated image display and analysis on IBM-based systems is presented. Designed specifically for a microcomputer, this program provides a wide-range of functions normally found only on dedicated graphics systems, and therefore can provide most students, universities and research groups with an affordable computer platform for processing digital images. The processing of AVHRR images within this environment is presented as an example.

The Cooking and Pneumonia Study (CAPS) in Malawi: Implementation of Remote Source Data Verification

PubMed Central

Weston, William; Smedley, James; Bennett, Andrew; Mortimer, Kevin

2016-01-01

Background Source data verification (SDV) is a data monitoring procedure which compares the original records with the Case Report Form (CRF). Traditionally, on-site SDV relies on monitors making multiples visits to study sites requiring extensive resources. The Cooking And Pneumonia Study (CAPS) is a 24- month village-level cluster randomized controlled trial assessing the effectiveness of an advanced cook-stove intervention in preventing pneumonia in children under five in rural Malawi (www.capstudy.org). CAPS used smartphones to capture digital images of the original records on an electronic CRF (eCRF). In the present study, descriptive statistics are used to report the experience of electronic data capture with remote SDV in a challenging research setting in rural Malawi. Methods At three monthly intervals, fieldworkers, who were employed by CAPS, captured pneumonia data from the original records onto the eCRF. Fieldworkers also captured digital images of the original records. Once Internet connectivity was available, the data captured on the eCRF and the digital images of the original records were uploaded to a web-based SDV application. This enabled SDV to be conducted remotely from the UK. We conducted SDV of the pneumonia data (occurrence, severity, and clinical indicators) recorded in the eCRF with the data in the digital images of the original records. Result 664 episodes of pneumonia were recorded after 6 months of follow-up. Of these 664 episodes, 611 (92%) had a finding of pneumonia in the original records. All digital images of the original records were clear and legible. Conclusion Electronic data capture using eCRFs on mobile technology is feasible in rural Malawi. Capturing digital images of the original records in the field allows remote SDV to be conducted efficiently and securely without requiring additional field visits. We recommend these approaches in similar settings, especially those with health endpoints. PMID:27355447

The Cooking and Pneumonia Study (CAPS) in Malawi: Implementation of Remote Source Data Verification.

PubMed

Weston, William; Smedley, James; Bennett, Andrew; Mortimer, Kevin

2016-01-01

Source data verification (SDV) is a data monitoring procedure which compares the original records with the Case Report Form (CRF). Traditionally, on-site SDV relies on monitors making multiples visits to study sites requiring extensive resources. The Cooking And Pneumonia Study (CAPS) is a 24- month village-level cluster randomized controlled trial assessing the effectiveness of an advanced cook-stove intervention in preventing pneumonia in children under five in rural Malawi (www.capstudy.org). CAPS used smartphones to capture digital images of the original records on an electronic CRF (eCRF). In the present study, descriptive statistics are used to report the experience of electronic data capture with remote SDV in a challenging research setting in rural Malawi. At three monthly intervals, fieldworkers, who were employed by CAPS, captured pneumonia data from the original records onto the eCRF. Fieldworkers also captured digital images of the original records. Once Internet connectivity was available, the data captured on the eCRF and the digital images of the original records were uploaded to a web-based SDV application. This enabled SDV to be conducted remotely from the UK. We conducted SDV of the pneumonia data (occurrence, severity, and clinical indicators) recorded in the eCRF with the data in the digital images of the original records. 664 episodes of pneumonia were recorded after 6 months of follow-up. Of these 664 episodes, 611 (92%) had a finding of pneumonia in the original records. All digital images of the original records were clear and legible. Electronic data capture using eCRFs on mobile technology is feasible in rural Malawi. Capturing digital images of the original records in the field allows remote SDV to be conducted efficiently and securely without requiring additional field visits. We recommend these approaches in similar settings, especially those with health endpoints.

Comparison of imaging characteristics of multiple-beam equalization and storage phosphor direct digitizer radiographic systems

NASA Astrophysics Data System (ADS)

Sankaran, A.; Chuang, Keh-Shih; Yonekawa, Hisashi; Huang, H. K.

1992-06-01

The imaging characteristics of two chest radiographic equipment, Advanced Multiple Beam Equalization Radiography (AMBER) and Konica Direct Digitizer [using a storage phosphor (SP) plate] systems have been compared. The variables affecting image quality and the computer display/reading systems used are detailed. Utilizing specially designed wedge, geometric, and anthropomorphic phantoms, studies were conducted on: exposure and energy response of detectors; nodule detectability; different exposure techniques; various look- up tables (LUTs), gray scale displays and laser printers. Methods for scatter estimation and reduction were investigated. It is concluded that AMBER with screen-film and equalization techniques provides better nodule detectability than SP plates. However, SP plates have other advantages such as flexibility in the selection of exposure techniques, image processing features, and excellent sensitivity when combined with optimum reader operating modes. The equalization feature of AMBER provides better nodule detectability under the denser regions of the chest. Results of diagnostic accuracy are demonstrated with nodule detectability plots and analysis of images obtained with phantoms.

[Diagnostic imaging of breast cancer : An update].

PubMed

Funke, M

2016-10-01

Advances in imaging of the female breast have substantially influenced the diagnosis and probably also the therapy and prognosis of breast cancer in the past few years. This article gives an overview of the most important imaging modalities in the diagnosis of breast cancer. Digital mammography is considered to be the gold standard for the early detection of breast cancer. Digital breast tomosynthesis can increase the diagnostic accuracy of mammography and is used for the assessment of equivocal or suspicious mammography findings. Other modalities, such as ultrasound and contrast-enhanced magnetic resonance imaging (MRI) play an important role in the diagnostics, staging and follow-up of breast cancer. Percutaneous needle biopsy is a rapid and minimally invasive method for the histological verification of breast cancer. New breast imaging modalities, such as contrast-enhanced spectral mammography, diffusion-weighted MRI and MR spectroscopy can possibly further improve breast cancer diagnostics; however, further studies are necessary to prove the advantages of these methods so that they cannot yet be recommended for routine clinical use.

The morphological classification of normal and abnormal red blood cell using Self Organizing Map

NASA Astrophysics Data System (ADS)

Rahmat, R. F.; Wulandari, F. S.; Faza, S.; Muchtar, M. A.; Siregar, I.

2018-02-01

Blood is an essential component of living creatures in the vascular space. For possible disease identification, it can be tested through a blood test, one of which can be seen from the form of red blood cells. The normal and abnormal morphology of the red blood cells of a patient is very helpful to doctors in detecting a disease. With the advancement of digital image processing technology can be used to identify normal and abnormal blood cells of a patient. This research used self-organizing map method to classify the normal and abnormal form of red blood cells in the digital image. The use of self-organizing map neural network method can be implemented to classify the normal and abnormal form of red blood cells in the input image with 93,78% accuracy testing.

Optronic System Imaging Simulator (OSIS): imager simulation tool of the ECOMOS project

NASA Astrophysics Data System (ADS)

Wegner, D.; Repasi, E.

2018-04-01

ECOMOS is a multinational effort within the framework of an EDA Project Arrangement. Its aim is to provide a generally accepted and harmonized European computer model for computing nominal Target Acquisition (TA) ranges of optronic imagers operating in the Visible or thermal Infrared (IR). The project involves close co-operation of defense and security industry and public research institutes from France, Germany, Italy, The Netherlands and Sweden. ECOMOS uses two approaches to calculate Target Acquisition (TA) ranges, the analytical TRM4 model and the image-based Triangle Orientation Discrimination model (TOD). In this paper the IR imager simulation tool, Optronic System Imaging Simulator (OSIS), is presented. It produces virtual camera imagery required by the TOD approach. Pristine imagery is degraded by various effects caused by atmospheric attenuation, optics, detector footprint, sampling, fixed pattern noise, temporal noise and digital signal processing. Resulting images might be presented to observers or could be further processed for automatic image quality calculations. For convenience OSIS incorporates camera descriptions and intermediate results provided by TRM4. For input OSIS uses pristine imagery tied with meta information about scene content, its physical dimensions, and gray level interpretation. These images represent planar targets placed at specified distances to the imager. Furthermore, OSIS is extended by a plugin functionality that enables integration of advanced digital signal processing techniques in ECOMOS such as compression, local contrast enhancement, digital turbulence mitiga- tion, to name but a few. By means of this image-based approach image degradations and image enhancements can be investigated, which goes beyond the scope of the analytical TRM4 model.

3D Printing and Digital Rock Physics for the Geosciences

NASA Astrophysics Data System (ADS)

Martinez, M. J.; Yoon, H.; Dewers, T. A.

2014-12-01

Imaging techniques for the analysis of porous structures have revolutionized our ability to quantitatively characterize geomaterials. For example, digital representations of rock from CT images and physics modeling based on these pore structures provide the opportunity to further advance our quantitative understanding of fluid flow, geomechanics, and geochemistry, and the emergence of coupled behaviors. Additive manufacturing, commonly known as 3D printing, has revolutionized production of custom parts, to the point where parts might be cheaper to print than to make by traditional means in a plant and ship. Some key benefits of additive manufacturing include short lead times, complex shapes, parts on demand, zero required inventory and less material waste. Even subtractive processing, such as milling and etching, may be economized by additive manufacturing. For the geosciences, recent advances in 3D printing technology may be co-opted to print reproducible porous structures derived from CT-imaging of actual rocks for experimental testing. The use of 3D printed microstructure allows us to surmount typical problems associated with sample-to-sample heterogeneity that plague rock physics testing and to test material response independent from pore-structure variability. Together, imaging, digital rocks and 3D printing potentially enables a new workflow for understanding coupled geophysical processes in a real, but well-defined setting circumventing typical issues associated with reproducibility, enabling full characterization and thus connection of physical phenomena to structure. In this talk we will discuss the possibilities that the marriage of these technologies can bring to geosciences, including examples from our current research initiatives in developing constitutive laws for transport and geomechanics via digital rock physics. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

EROS Data Center Landsat digital enhancement techniques and imagery availability

USGS Publications Warehouse

Rohde, Wayne G.; Lo, Jinn Kai; Pohl, Russell A.

1978-01-01

The US Geological Survey's EROS Data Center (EDC) is experimenting with the production of digitally enhanced Landsat imagery. Advanced digital image processing techniques are used to perform geometric and radiometric corrections and to perform contrast and edge enhancements. The enhanced image product is produced from digitally preprocessed Landsat computer compatible tapes (CCTs) on a laser beam film recording system. Landsat CCT data have several geometric distortions which are corrected when NASA produces the standard film products. When producing film images from CCT's, geometric correction of the data is required. The EDC Digital Image Enhancement System (EDIES) compensates for geometric distortions introduced by Earth's rotation, variable line length, non-uniform mirror scan velocity, and detector misregistration. Radiometric anomalies such as bad data lines and striping are common to many Landsat film products and are also in the CCT data. Bad data lines or line segments with more than 150 contiguous bad pixels are corrected by inserting data from the previous line in place of the bad data. Striping, caused by variations in detector gain and offset, is removed with a destriping algorithm applied after digitally enhancing the data. Image enhancement is performed by applying a linear contrast stretch and an edge enhancement algorithm. The linear contrast enhancement algorithm is designed to expand digitally the full range of useful data recorded on the CCT over the range of 256 digital counts. This minimizes the effect of atmospheric scattering and saturates the relative brightness of highly reflecting features such as clouds or snow. It is the intent that no meaningful terrain data are eliminated by the digital processing. The edge enhancement algorithm is designed to enhance boundaries between terrain features that exhibit subtle differences in brightness values along edges of features. After the digital data have been processed, data for each Landsat band are recorded on black-and-white film with a laser beam film recorder (LBR). The LBR corrects for aspect ratio distortions as the digital data are recorded on the recording film over a preselected density range. Positive transparencies of MSS bands 4, 5, and 7 produced by the LBR are used to make color composite transparencies. Color film positives are made photographically from first generation black-and-white products generated on the LBR.

Earth Observing-1 Advanced Imager Flight Performance Assessment: Investigating Dark Current Stability Over One-Half Orbit Period during the First 60 Days

NASA Technical Reports Server (NTRS)

Mendenhall, J. A.

2001-01-01

The stability of the EO-1 Advanced Land Imager dark current levels over the period of one-half orbit is investigated. A series of two-second dark current collections, over the course of 40 minutes, was performed during the first sixty days the instrument was in orbit. Analysis of this data indicates only two dark current reference periods, obtained entering and exiting eclipse, are required to remove ALI dark current offsets for 99.9% of the focal plane to within 1.5 digital numbers for any observation on the solar illuminated portion of the orbit.

Electronic Referrals and Digital Imaging Systems in Ophthalmology: A Global Perspective.

PubMed

Jeganathan, V Swetha E; Hall, H Nikki; Sanders, Roshini

2017-01-01

Ophthalmology departments face intensifying pressure to expedite sight-saving treatments and reduce the global burden of disease. The use of electronic communication systems, digital imaging, and redesigned service care models is imperative for addressing such demands. The recently developed Scottish Eyecare Integration Project involves an electronic referral system from community optometry to the hospital ophthalmology department using National Health Service (NHS) email with digital ophthalmic images attached, via a virtual private network connection. The benefits over the previous system include reduced waiting times, improved triage, e-diagnosis in 20% without the need for hospital attendance, and rapid electronic feedback to referrers. We draw on the experience of the Scottish Eyecare Integration Project and discuss the global applications of this and other advances in teleophthalmology. We focus particularly on the implications for management and screening of chronic disease, such as glaucoma and diabetic eye disease, and ophthalmic disease, such as retinopathy of prematurity where diagnosis is almost entirely and critically dependent on fundus appearance. Currently in Scotland, approximately 75% of all referrals are electronic from community to hospital. The Scottish Eyecare Integration Project is globally the first of its kind and unique in a national health service. Such speedy, safe, and efficient models of communication are geographically sensitive to service provision, especially in remote and rural regions. Along with advances in teleophthalmology, such systems promote the earlier detection of sight-threatening disease and safe follow-up of non-sight-threatening disease in the community. Copyright© 2017 Asia-Pacific Academy of Ophthalmology.

Uses of megavoltage digital tomosynthesis in radiotherapy

NASA Astrophysics Data System (ADS)

Sarkar, Vikren

With the advent of intensity modulated radiotherapy, radiation treatment plans are becoming more conformal to the tumor with the decreasing margins. It is therefore of prime importance that the patient be positioned correctly prior to treatment. Therefore, image guided treatment is necessary for intensity modulated radiotherapy plans to be implemented successfully. Current advanced imaging devices require costly hardware and software upgrade, and radiation imaging solutions, such as cone beam computed tomography, may introduce extra radiation dose to the patient in order to acquire better quality images. Thus, there is a need to extend current existing imaging device ability and functions while reducing cost and radiation dose. Existing electronic portal imaging devices can be used to generate computed tomography-like tomograms through projection images acquired over a small angle using the technique of cone-beam digital tomosynthesis. Since it uses a fraction of the images required for computed tomography reconstruction, use of this technique correspondingly delivers only a fraction of the imaging dose to the patient. Furthermore, cone-beam digital tomosynthesis can be offered as a software-only solution as long as a portal imaging device is available. In this study, the feasibility of performing digital tomosynthesis using individually-acquired megavoltage images from a charge coupled device-based electronic portal imaging device was investigated. Three digital tomosynthesis reconstruction algorithms, the shift-and-add, filtered back-projection, and simultaneous algebraic reconstruction technique, were compared considering the final image quality and radiation dose during imaging. A software platform, DART, was created using a combination of the Matlab and C++ languages. The platform allows for the registration of a reference Cone Beam Digital Tomosynthesis (CBDT) image against a daily acquired set to determine how to shift the patient prior to treatment. Finally, the software was extended to investigate if the digital tomosynthesis dataset could be used in an adaptive radiotherapy regimen through the use of the Pinnacle treatment planning software to recalculate dose delivered. The feasibility study showed that the megavoltage CBDT visually agreed with corresponding megavoltage computed tomography images. The comparative study showed that the best compromise between imaging quality and imaging dose is obtained when 11 projection images, acquired over an imaging angle of 40°, are used with the filtered back-projection algorithm. DART was successfully used to register reference and daily image sets to within 1 mm in-plane and 2.5 mm out of plane. The DART platform was also effectively used to generate updated files that the Pinnacle treatment planning system used to calculate updated dose in a rigidly shifted patient. These doses were then used to calculate a cumulative dose distribution that could be used by a physician as reference to decide when the treatment plan should be updated. In conclusion, this study showed that a software solution is possible to extend existing electronic portal imaging devices to function as cone-beam digital tomosynthesis devices and achieve daily requirement for image guided intensity modulated radiotherapy treatments. The DART platform also has the potential to be used as a part of adaptive radiotherapy solution.

The Chinese Visible Human (CVH) datasets incorporate technical and imaging advances on earlier digital humans

PubMed Central

Zhang, Shao-Xiang; Heng, Pheng-Ann; Liu, Zheng-Jin; Tan, Li-Wen; Qiu, Ming-Guo; Li, Qi-Yu; Liao, Rong-Xia; Li, Kai; Cui, Gao-Yu; Guo, Yan-Li; Yang, Xiao-Ping; Liu, Guang-Jiu; Shan, Jing-Lu; Liu, Ji-Jun; Zhang, Wei-Guo; Chen, Xian-Hong; Chen, Jin-Hua; Wang, Jian; Chen, Wei; Lu, Ming; You, Jian; Pang, Xue-Li; Xiao, Hong; Xie, Yong-Ming; Cheng, Jack Chun-Yiu

2004-01-01

We report the availability of a digitized Chinese male and a digitzed Chinese female typical of the population and with no obvious abnormalities. The embalming and milling procedures incorporate three technical improvements over earlier digitized cadavers. Vascular perfusion with coloured gelatin was performed to facilitate blood vessel identification. Embalmed cadavers were embedded in gelatin and cryosectioned whole so as to avoid section loss resulting from cutting the body into smaller pieces. Milling performed at −25 °C prevented small structures (e.g. teeth, concha nasalis and articular cartilage) from falling off from the milling surface. The male image set (.tiff images each of 36 Mb) has a section resolution of 3072 × 2048 pixels (∼170 μm, the accompanying magnetic resonance imaging and computer tomography data have a resolution of 512 × 512, i.e. ∼440 μm). The Chinese Visible Human male and female datasets are available at http://www.chinesevisiblehuman.com. (The male is 90.65 Gb and female 131.04 Gb). MPEG videos of direct records of real-time volume rendering are at: http://www.cse.cuhk.edu.hk/~crc PMID:15032906

Meeting Report: Tissue-based Image Analysis.

PubMed

Saravanan, Chandra; Schumacher, Vanessa; Brown, Danielle; Dunstan, Robert; Galarneau, Jean-Rene; Odin, Marielle; Mishra, Sasmita

2017-10-01

Quantitative image analysis (IA) is a rapidly evolving area of digital pathology. Although not a new concept, the quantification of histological features on photomicrographs used to be cumbersome, resource-intensive, and limited to specialists and specialized laboratories. Recent technological advances like highly efficient automated whole slide digitizer (scanner) systems, innovative IA platforms, and the emergence of pathologist-friendly image annotation and analysis systems mean that quantification of features on histological digital images will become increasingly prominent in pathologists' daily professional lives. The added value of quantitative IA in pathology includes confirmation of equivocal findings noted by a pathologist, increasing the sensitivity of feature detection, quantification of signal intensity, and improving efficiency. There is no denying that quantitative IA is part of the future of pathology; however, there are also several potential pitfalls when trying to estimate volumetric features from limited 2-dimensional sections. This continuing education session on quantitative IA offered a broad overview of the field; a hands-on toxicologic pathologist experience with IA principles, tools, and workflows; a discussion on how to apply basic stereology principles in order to minimize bias in IA; and finally, a reflection on the future of IA in the toxicologic pathology field.

Safety and efficacy for new techniques and imaging using new equipment to support European legislation: an EU coordination action.

PubMed

Zoetelief, J; Faulkner, K

2008-01-01

The past two decades have witnessed a technologically driven revolution in radiology. At the centre of these developments has been the use of computing. These developments have also been driven by the introduction of new detector and imaging devices in radiology and nuclear medicine, as well as the widespread application of computing techniques to enhance and extract information within the images acquired. Further advances have been introduced into digital practice. These technological developments, however, have not been matched by justification and optimisation studies to ensure that these new imaging devices and techniques are as effective as they might be, or performed at the lowest possible dose. The work programme of the SENTINEL Coordination Action was subdivided into eight work packages: functional performance and standards; efficacy and safety in digital radiology, dentistry and nuclear medicine, cardiology, interventional radiology, population screening/sensitive groups; justification, ethics and efficacy; good practice guidance and training; and project management. The intention of the work programme was to underwrite the safety, efficacy and ethical aspects of digital practice as well as to protect and add value to the equipment used in radiology.

SU-E-J-02: 4D Digital Tomosynthesis Based On Algebraic Image Reconstruction and Total-Variation Minimization for the Improvement of Image Quality

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, D; Kang, S; Kim, T

2014-06-01

Purpose: In this paper, we implemented the four-dimensional (4D) digital tomosynthesis (DTS) imaging based on algebraic image reconstruction technique and total-variation minimization method in order to compensate the undersampled projection data and improve the image quality. Methods: The projection data were acquired as supposed the cone-beam computed tomography system in linear accelerator by the Monte Carlo simulation and the in-house 4D digital phantom generation program. We performed 4D DTS based upon simultaneous algebraic reconstruction technique (SART) among the iterative image reconstruction technique and total-variation minimization method (TVMM). To verify the effectiveness of this reconstruction algorithm, we performed systematic simulation studiesmore » to investigate the imaging performance. Results: The 4D DTS algorithm based upon the SART and TVMM seems to give better results than that based upon the existing method, or filtered-backprojection. Conclusion: The advanced image reconstruction algorithm for the 4D DTS would be useful to validate each intra-fraction motion during radiation therapy. In addition, it will be possible to give advantage to real-time imaging for the adaptive radiation therapy. This research was supported by Leading Foreign Research Institute Recruitment Program (Grant No.2009-00420) and Basic Atomic Energy Research Institute (BAERI); (Grant No. 2009-0078390) through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and Future Planning (MSIP)« less

Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

NASA Astrophysics Data System (ADS)

Wang, Y.; Tobias, B.; Chang, Y.-T.; Yu, J.-H.; Li, M.; Hu, F.; Chen, M.; Mamidanna, M.; Phan, T.; Pham, A.-V.; Gu, J.; Liu, X.; Zhu, Y.; Domier, C. W.; Shi, L.; Valeo, E.; Kramer, G. J.; Kuwahara, D.; Nagayama, Y.; Mase, A.; Luhmann, N. C., Jr.

2017-07-01

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. Microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These have the potential to greatly advance microwave fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfvén eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today’s most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.

Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

DOE PAGES

Wang, Y.; Tobias, B.; Chang, Y. -T.; ...

2017-03-14

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. The microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These also have the potential to greatly advance microwavemore » fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfven eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today's most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.« less

Retinal imaging analysis based on vessel detection.

PubMed

Jamal, Arshad; Hazim Alkawaz, Mohammed; Rehman, Amjad; Saba, Tanzila

2017-07-01

With an increase in the advancement of digital imaging and computing power, computationally intelligent technologies are in high demand to be used in ophthalmology cure and treatment. In current research, Retina Image Analysis (RIA) is developed for optometrist at Eye Care Center in Management and Science University. This research aims to analyze the retina through vessel detection. The RIA assists in the analysis of the retinal images and specialists are served with various options like saving, processing and analyzing retinal images through its advanced interface layout. Additionally, RIA assists in the selection process of vessel segment; processing these vessels by calculating its diameter, standard deviation, length, and displaying detected vessel on the retina. The Agile Unified Process is adopted as the methodology in developing this research. To conclude, Retina Image Analysis might help the optometrist to get better understanding in analyzing the patient's retina. Finally, the Retina Image Analysis procedure is developed using MATLAB (R2011b). Promising results are attained that are comparable in the state of art. © 2017 Wiley Periodicals, Inc.

Ultra-high-speed variable focus optics for novel applications in advanced imaging

NASA Astrophysics Data System (ADS)

Kang, S.; Dotsenko, E.; Amrhein, D.; Theriault, C.; Arnold, C. B.

2018-02-01

With the advancement of ultra-fast manufacturing technologies, high speed imaging with high 3D resolution has become increasingly important. Here we show the use of an ultra-high-speed variable focus optical element, the TAG Lens, to enable new ways to acquire 3D information from an object. The TAG Lens uses sound to adjust the index of refraction profile in a liquid and thereby can achieve focal scanning rates greater than 100 kHz. When combined with a high-speed pulsed LED and a high-speed camera, we can exploit this phenomenon to achieve high-resolution imaging through large depths. By combining the image acquisition with digital image processing, we can extract relevant parameters such as tilt and angle information from objects in the image. Due to the high speeds at which images can be collected and processed, we believe this technique can be used as an efficient method of industrial inspection and metrology for high throughput applications.

Harvey Mudd College: Technology Integration Offers Unique Opportunities for Undergraduates.

ERIC Educational Resources Information Center

Barna, John; Winstead, Jim

1993-01-01

Describes undergraduate projects at Harvey Mudd College (California) that use advanced laboratory equipment and procedures normally reserved for graduate students. Examples are given in experimental biology (e.g., digital imaging and DNA analysis), in physics (e.g., using satellites to study earthquake faults), and in mathematics (e.g., teaching…

Social Operational Information, Competence, and Participation in Online Collective Action

ERIC Educational Resources Information Center

Antin, Judd David

2010-01-01

Recent advances in interactive web technologies, combined with widespread broadband and mobile device adoption, have made online collective action commonplace. Millions of individuals work together to aggregate, annotate, and share digital text, audio, images, and video. Given the prevalence and importance of online collective action systems,…

3D digital image correlation methods for full-field vibration measurement

NASA Astrophysics Data System (ADS)

Helfrick, Mark N.; Niezrecki, Christopher; Avitabile, Peter; Schmidt, Timothy

2011-04-01

In the area of modal test/analysis/correlation, significant effort has been expended over the past twenty years in order to make reduced models and to expand test data for correlation and eventual updating of the finite element models. This has been restricted by vibration measurements which are traditionally limited to the location of relatively few applied sensors. Advances in computers and digital imaging technology have allowed 3D digital image correlation (DIC) methods to measure the shape and deformation of a vibrating structure. This technique allows for full-field measurement of structural response, thus providing a wealth of simultaneous test data. This paper presents some preliminary results for the test/analysis/correlation of data measured using the DIC approach along with traditional accelerometers and a scanning laser vibrometer for comparison to a finite element model. The results indicate that all three approaches correlated well with the finite element model and provide validation for the DIC approach for full-field vibration measurement. Some of the advantages and limitations of the technique are presented and discussed.

Development of a prototype chest digital tomosynthesis (CDT) R/F system with fast image reconstruction using graphics processing unit (GPU) programming

NASA Astrophysics Data System (ADS)

Choi, Sunghoon; Lee, Seungwan; Lee, Haenghwa; Lee, Donghoon; Choi, Seungyeon; Shin, Jungwook; Seo, Chang-Woo; Kim, Hee-Joung

2017-03-01

Digital tomosynthesis offers the advantage of low radiation doses compared to conventional computed tomography (CT) by utilizing small numbers of projections ( 80) acquired over a limited angular range. It produces 3D volumetric data, although there are artifacts due to incomplete sampling. Based upon these characteristics, we developed a prototype digital tomosynthesis R/F system for applications in chest imaging. Our prototype chest digital tomosynthesis (CDT) R/F system contains an X-ray tube with high power R/F pulse generator, flat-panel detector, R/F table, electromechanical radiographic subsystems including a precise motor controller, and a reconstruction server. For image reconstruction, users select between analytic and iterative reconstruction methods. Our reconstructed images of Catphan700 and LUNGMAN phantoms clearly and rapidly described the internal structures of phantoms using graphics processing unit (GPU) programming. Contrast-to-noise ratio (CNR) values of the CTP682 module of Catphan700 were higher in images using a simultaneous algebraic reconstruction technique (SART) than in those using filtered back-projection (FBP) for all materials by factors of 2.60, 3.78, 5.50, 2.30, 3.70, and 2.52 for air, lung foam, low density polyethylene (LDPE), Delrin® (acetal homopolymer resin), bone 50% (hydroxyapatite), and Teflon, respectively. Total elapsed times for producing 3D volume were 2.92 s and 86.29 s on average for FBP and SART (20 iterations), respectively. The times required for reconstruction were clinically feasible. Moreover, the total radiation dose from our system (5.68 mGy) was lower than that of conventional chest CT scan. Consequently, our prototype tomosynthesis R/F system represents an important advance in digital tomosynthesis applications.

Cervical digit in a child

PubMed Central

Tong, Min-Ji; Xiang, Guang-Heng; He, Zi-Li; Xu, Hua-Zi; Tian, Nai-Feng

2017-01-01

Abstract Background: A “digit-like” bone is a rare developmental anomaly that is usually seen in the pelvic or thoracic regions. Such an anomaly in the cervical spine is extremely rare and few cases have been reported. We present a patient with an anomalous bone posterior to a cervical vertebra. The patient was admitted to our hospital with a gradually growing hard neck mass and esthetic complaints. Physical examination, radiographs, reconstructed computed tomography, and magnetic resonance imaging revealed a digit-like bone posterior to the cervical spine. The patient was diagnosed with a “cervical digit.” Through a posterior midline approach, the anomalous bone was excised because of its gradually increasing size and esthetic complaints. Results: Intraoperatively, the bony mass was found to have a pseudoarticulation with the spinous process of C5 (the fifth cervical vertebra). The specimen consisted of normal bone and cartilage. The child returned to a normal life postoperatively with no symptoms. There was no recurrence at the 2-year follow-up. Conclusion: A congenital cervical digit is a rare deformity. A detailed clinical workup and advanced imaging examinations are useful for diagnosing such conditions. Esthetic complaints contribute to surgical indications. This is the first cervical digit managed with surgical excision of the anomalous bone and had a favorable outcome. PMID:29390517

A novel speckle pattern—Adaptive digital image correlation approach with robust strain calculation

NASA Astrophysics Data System (ADS)

Cofaru, Corneliu; Philips, Wilfried; Van Paepegem, Wim

2012-02-01

Digital image correlation (DIC) has seen widespread acceptance and usage as a non-contact method for the determination of full-field displacements and strains in experimental mechanics. The advances of imaging hardware in the last decades led to high resolution and speed cameras being more affordable than in the past making large amounts of data image available for typical DIC experimental scenarios. The work presented in this paper is aimed at maximizing both the accuracy and speed of DIC methods when employed with such images. A low-level framework for speckle image partitioning which replaces regularly shaped blocks with image-adaptive cells in the displacement calculation is introduced. The Newton-Raphson DIC method is modified to use the image pixels of the cells and to perform adaptive regularization to increase the spatial consistency of the displacements. Furthermore, a novel robust framework for strain calculation based also on the Newton-Raphson algorithm is introduced. The proposed methods are evaluated in five experimental scenarios, out of which four use numerically deformed images and one uses real experimental data. Results indicate that, as the desired strain density increases, significant computational gains can be obtained while maintaining or improving accuracy and rigid-body rotation sensitivity.

Flight instruments and helmet-mounted SWIR imaging systems

NASA Astrophysics Data System (ADS)

Robinson, Tim; Green, John; Jacobson, Mickey; Grabski, Greg

2011-06-01

Night vision technology has experienced significant advances in the last two decades. Night vision goggles (NVGs) based on gallium arsenide (GaAs) continues to raise the bar for alternative technologies. Resolution, gain, sensitivity have all improved; the image quality through these devices is nothing less than incredible. Panoramic NVGs and enhanced NVGs are examples of recent advances that increase the warfighter capabilities. Even with these advances, alternative night vision devices such as solid-state indium gallium arsenide (InGaAs) focal plane arrays are under development for helmet-mounted imaging systems. The InGaAs imaging system offers advantages over the existing NVGs. Two key advantages are; (1) the new system produces digital image data, and (2) the new system is sensitive to energy in the shortwave infrared (SWIR) spectrum. While it is tempting to contrast the performance of these digital systems to the existing NVGs, the advantage of different spectral detection bands leads to the conclusion that the technologies are less competitive and more synergistic. It is likely, by the end of the decade, pilots within a cockpit will use multi-band devices. As such, flight decks will need to be compatible with both NVGs and SWIR imaging systems. Insertion of NVGs in aircraft during the late 70's and early 80's resulted in many "lessons learned" concerning instrument compatibility with NVGs. These "lessons learned" ultimately resulted in specifications such as MIL-L-85762A and MIL-STD-3009. These specifications are now used throughout industry to produce NVG-compatible illuminated instruments and displays for both military and civilian applications. Inserting a SWIR imaging device in a cockpit will require similar consideration. A project evaluating flight deck instrument compatibility with SWIR devices is currently ongoing; aspects of this evaluation are described in this paper. This project is sponsored by the Air Force Research Laboratory (AFRL).

Mediaprocessors in medical imaging for high performance and flexibility

NASA Astrophysics Data System (ADS)

Managuli, Ravi; Kim, Yongmin

2002-05-01

New high performance programmable processors, called mediaprocessors, have been emerging since the early 1990s for various digital media applications, such as digital TV, set-top boxes, desktop video conferencing, and digital camcorders. Modern mediaprocessors, e.g., TI's TMS320C64x and Hitachi/Equator Technologies MAP-CA, can offer high performance utilizing both instruction-level and data-level parallelism. During this decade, with continued performance improvement and cost reduction, we believe that the mediaprocessors will become a preferred choice in designing imaging and video systems due to their flexibility in incorporating new algorithms and applications via programming and faster-time-to-market. In this paper, we will evaluate the suitability of these mediaprocessors in medical imaging. We will review the core routines of several medical imaging modalities, such as ultrasound and DR, and present how these routines can be mapped to mediaprocessors and their resultant performance. We will analyze the architecture of several leading mediaprocessors. By carefully mapping key imaging routines, such as 2D convolution, unsharp masking, and 2D FFT, to the mediaprocessor, we have been able to achieve comparable (if not better) performance to that of traditional hardwired approaches. Thus, we believe that future medical imaging systems will benefit greatly from these advanced mediaprocessors, offering significantly increased flexibility and adaptability, reducing the time-to-market, and improving the cost/performance ratio compared to the existing systems while meeting the high computing requirements.

A Q-Ising model application for linear-time image segmentation

NASA Astrophysics Data System (ADS)

Bentrem, Frank W.

2010-10-01

A computational method is presented which efficiently segments digital grayscale images by directly applying the Q-state Ising (or Potts) model. Since the Potts model was first proposed in 1952, physicists have studied lattice models to gain deep insights into magnetism and other disordered systems. For some time, researchers have realized that digital images may be modeled in much the same way as these physical systems ( i.e., as a square lattice of numerical values). A major drawback in using Potts model methods for image segmentation is that, with conventional methods, it processes in exponential time. Advances have been made via certain approximations to reduce the segmentation process to power-law time. However, in many applications (such as for sonar imagery), real-time processing requires much greater efficiency. This article contains a description of an energy minimization technique that applies four Potts (Q-Ising) models directly to the image and processes in linear time. The result is analogous to partitioning the system into regions of four classes of magnetism. This direct Potts segmentation technique is demonstrated on photographic, medical, and acoustic images.

CMOS cassette for digital upgrade of film-based mammography systems

NASA Astrophysics Data System (ADS)

Baysal, Mehmet A.; Toker, Emre

2006-03-01

While full-field digital mammography (FFDM) technology is gaining clinical acceptance, the overwhelming majority (96%) of the installed base of mammography systems are conventional film-screen (FSM) systems. A high performance, and economical digital cassette based product to conveniently upgrade FSM systems to FFDM would accelerate the adoption of FFDM, and make the clinical and technical advantages of FFDM available to a larger population of women. The planned FFDM cassette is based on our commercial Digital Radiography (DR) cassette for 10 cm x 10 cm field-of-view spot imaging and specimen radiography, utilizing a 150 micron columnar CsI(Tl) scintillator and 48 micron active-pixel CMOS sensor modules. Unlike a Computer Radiography (CR) cassette, which requires an external digitizer, our DR cassette transfers acquired images to a display workstation within approximately 5 seconds of exposure, greatly enhancing patient flow. We will present the physical performance of our prototype system against other FFDM systems in clinical use today, using established objective criteria such as the Modulation Transfer Function (MTF), Detective Quantum Efficiency (DQE), and subjective criteria, such as a contrast-detail (CD-MAM) observer performance study. Driven by the strong demand from the computer industry, CMOS technology is one of the lowest cost, and the most readily accessible technologies available for FFDM today. Recent popular use of CMOS imagers in high-end consumer cameras have also resulted in significant advances in the imaging performance of CMOS sensors against rivaling CCD sensors. This study promises to take advantage of these unique features to develop the first CMOS based FFDM upgrade cassette.

Digital image analysis in pathology: benefits and obligation.

PubMed

Laurinavicius, Arvydas; Laurinaviciene, Aida; Dasevicius, Darius; Elie, Nicolas; Plancoulaine, Benoît; Bor, Catherine; Herlin, Paulette

2012-01-01

Pathology has recently entered the era of personalized medicine. This brings new expectations for the accuracy and precision of tissue-based diagnosis, in particular, when quantification of histologic features and biomarker expression is required. While for many years traditional pathologic diagnosis has been regarded as ground truth, this concept is no longer sufficient in contemporary tissue-based biomarker research and clinical use. Another major change in pathology is brought by the advancement of virtual microscopy technology enabling digitization of microscopy slides and presenting new opportunities for digital image analysis. Computerized vision provides an immediate benefit of increased capacity (automation) and precision (reproducibility), but not necessarily the accuracy of the analysis. To achieve the benefit of accuracy, pathologists will have to assume an obligation of validation and quality assurance of the image analysis algorithms. Reference values are needed to measure and control the accuracy. Although pathologists' consensus values are commonly used to validate these tools, we argue that the ground truth can be best achieved by stereology methods, estimating the same variable as an algorithm is intended to do. Proper adoption of the new technology will require a new quantitative mentality in pathology. In order to see a complete and sharp picture of a disease, pathologists will need to learn to use both their analogue and digital eyes.

“Slide less pathology”: Fairy tale or reality?

PubMed Central

Indu, M; Rathy, R; Binu, MP

2016-01-01

Pathology practice is significantly advanced in various frontiers. Therefore, “slide less digital” pathology will not be a mere imagination in near future. Digitalization of histopathological slides (whole slide imaging [WSI]) is possible with the help of whole slide scanner. The WSI has a positive impact not only in routine practice but also in research field, medical education and bioindustry. Even if digital pathology has definitive advantages, its widespread use is not yet possible. As it is an upcoming technology in our field, this article is aimed to discussessential aspects of WSI. PMID:27601824

NASA's Earth Science Use of Commercially Availiable Remote Sensing Datasets: Cover Image

NASA Technical Reports Server (NTRS)

Underwood, Lauren W.; Goward, Samuel N.; Fearon, Matthew G.; Fletcher, Rose; Garvin, Jim; Hurtt, George

2008-01-01

The cover image incorporates high resolution stereo pairs acquired from the DigitalGlobe(R) QuickBird sensor. It shows a digital elevation model of Meteor Crater, Arizona at approximately 1.3 meter point-spacing. Image analysts used the Leica Photogrammetry Suite to produce the DEM. The outside portion was computed from two QuickBird panchromatic scenes acquired October 2006, while an Optech laser scan dataset was used for the crater s interior elevations. The crater s terrain model and image drape were created in a NASA Constellation Program project focused on simulating lunar surface environments for prototyping and testing lunar surface mission analysis and planning tools. This work exemplifies NASA s Scientific Data Purchase legacy and commercial high resolution imagery applications, as scientists use commercial high resolution data to examine lunar analog Earth landscapes for advanced planning and trade studies for future lunar surface activities. Other applications include landscape dynamics related to volcanism, hydrologic events, climate change, and ice movement.

Operational experience with DICOM for the clinical specialties in the healthcare enterprise

NASA Astrophysics Data System (ADS)

Kuzmak, Peter M.; Dayhoff, Ruth E.

2004-04-01

A number of clinical specialties routinely use images in treating patients, for example ophthalmology, dentistry, cardiology, endoscopy, and surgery. These images are captured by a variety of commercial digital image acquisition systems. The US Department of Veterans Affairs has been working for several years on advancing the use of the Digital Imaging and Communications in Medicine (DICOM) Standard in these clinical specialties. This is an effort that has involved several facets: (1) working with the vendors to ensure that they satisfy existing DICOM requirements, (2) developing interface software to the VistA hospital information system (HIS), (3) field testing DICOM systems, (4) deploying these DICOM interfaces nation-wide to all VA medical centers, (5) working with the healthcare providers using the system, and (6) participating in the DICOM working groups to improve the standard. The VA is now beginning to develop clinical applications that make use of the DICOM interfaces in the clinical specialties. The first of these will be in ophthalmology to remotely screen patients for diabetic retinopathy.

QWIP technology for both military and civilian applications

NASA Astrophysics Data System (ADS)

Gunapala, Sarath D.; Kukkonen, Carl A.; Sirangelo, Mark N.; McQuiston, Barbara K.; Chehayeb, Riad; Kaufmann, M.

2001-10-01

Advanced thermal imaging infrared cameras have been a cost effective and reliable method to obtain the temperature of objects. Quantum Well Infrared Photodetector (QWIP) based thermal imaging systems have advanced the state-of-the-art and are the most sensitive commercially available thermal systems. QWIP Technologies LLC, under exclusive agreement with Caltech University, is currently manufacturing the QWIP-ChipTM, a 320 X 256 element, bound-to-quasibound QWIP FPA. The camera performance falls within the long-wave IR band, spectrally peaked at 8.5 μm. The camera is equipped with a 32-bit floating-point digital signal processor combined with multi- tasking software, delivering a digital acquisition resolution of 12-bits using nominal power consumption of less than 50 Watts. With a variety of video interface options, remote control capability via an RS-232 connection, and an integrated control driver circuit to support motorized zoom and focus- compatible lenses, this camera design has excellent application in both the military and commercial sector. In the area of remote sensing, high-performance QWIP systems can be used for high-resolution, target recognition as part of a new system of airborne platforms (including UAVs). Such systems also have direct application in law enforcement, surveillance, industrial monitoring and road hazard detection systems. This presentation will cover the current performance of the commercial QWIP cameras, conceptual platform systems and advanced image processing for use in both military remote sensing and civilian applications currently being developed in road hazard monitoring.

Computer-aided prognosis on breast cancer with hematoxylin and eosin histopathology images: A review.

PubMed

Chen, Jia-Mei; Li, Yan; Xu, Jun; Gong, Lei; Wang, Lin-Wei; Liu, Wen-Lou; Liu, Juan

2017-03-01

With the advance of digital pathology, image analysis has begun to show its advantages in information analysis of hematoxylin and eosin histopathology images. Generally, histological features in hematoxylin and eosin images are measured to evaluate tumor grade and prognosis for breast cancer. This review summarized recent works in image analysis of hematoxylin and eosin histopathology images for breast cancer prognosis. First, prognostic factors for breast cancer based on hematoxylin and eosin histopathology images were summarized. Then, usual procedures of image analysis for breast cancer prognosis were systematically reviewed, including image acquisition, image preprocessing, image detection and segmentation, and feature extraction. Finally, the prognostic value of image features and image feature-based prognostic models was evaluated. Moreover, we discussed the issues of current analysis, and some directions for future research.

Serious Gaming Technologies Support Human Factors Investigations of Advanced Interfaces for Semi-Autonomous Vehicles

DTIC Science & Technology

2006-06-01

conventional camera vs. thermal imager vs. night vision; camera field of view (narrow, wide, panoramic); keyboard + mouse vs. joystick control vs...motorised platform which could scan the immediate area, producing a 360o panorama of “stitched-together” digital pictures. The picture file, together with...VBS was used to automate the process of creating a QuickTime panorama (.mov or .qt), which includes the initial retrieval of the images, the

Automatic microscopy for mitotic cell location.

NASA Technical Reports Server (NTRS)

Herron, J.; Ranshaw, R.; Castle, J.; Wald, N.

1972-01-01

Advances are reported in the development of an automatic microscope with which to locate hematologic or other cells in mitosis for subsequent chromosome analysis. The system under development is designed to perform the functions of: slide scanning to locate metaphase cells; conversion of images of selected cells into binary form; and on-line computer analysis of the digitized image for significant cytogenetic data. Cell detection criteria are evaluated using a test sample of 100 mitotic cells and 100 artifacts.

Automation in photogrammetry: Recent developments and applications (1972-1976)

USGS Publications Warehouse

Thompson, M.M.; Mikhail, E.M.

1976-01-01

An overview of recent developments in the automation of photogrammetry in various countries is presented. Conclusions regarding automated photogrammetry reached at the 1972 Congress in Ottawa are reviewed first as a background for examining the developments of 1972-1976. Applications are described for each country reporting significant developments. Among fifteen conclusions listed are statements concerning: the widespread practice of equipping existing stereoplotters with simple digitizers; the growing tendency to use minicomputers on-line with stereoplotters; the optimization of production of digital terrain models by progressive sampling in stereomodels; the potential of digitization of a photogrammetric model by density correlation on epipolar lines; the capabilities and economic aspects of advanced systems which permit simultaneous production of orthophotos, contours, and digital terrain models; the economy of off-line orthophoto systems; applications of digital image processing; automation by optical techniques; applications of sensors other than photographic imagery, and the role of photogrammetric phases in a completely automated cartographic system. ?? 1976.

Combining Art and Science in "Arts and Sciences" Education

ERIC Educational Resources Information Center

Needle, Andrew; Corbo, Christopher; Wong, Denise; Greenfeder, Gary; Raths, Linda; Fulop, Zoltan

2007-01-01

Two of this article's authors--an art professor and a biology professor--shared a project for advanced biology, art, nursing, and computer science majors involving scientific research that used digital imaging of the brain of the zebrafish, a newly favored laboratory animal. These contemporary and innovative teaching and learning practices were a…

Extending the Life of Virtual Heritage: Reuse of Tls Point Clouds in Synthetic Stereoscopic Spherical Images

NASA Astrophysics Data System (ADS)

Garcia Fernandez, J.; Tammi, K.; Joutsiniemi, A.

2017-02-01

Recent advances in Terrestrial Laser Scanner (TLS), in terms of cost and flexibility, have consolidated this technology as an essential tool for the documentation and digitalization of Cultural Heritage. However, once the TLS data is used, it basically remains stored and left to waste.How can highly accurate and dense point clouds (of the built heritage) be processed for its reuse, especially to engage a broader audience? This paper aims to answer this question by a channel that minimizes the need for expert knowledge, while enhancing the interactivity with the as-built digital data: Virtual Heritage Dissemination through the production of VR content. Driven by the ProDigiOUs project's guidelines on data dissemination (EU funded), this paper advances in a production path to transform the point cloud into virtual stereoscopic spherical images, taking into account the different visual features that produce depth perception, and especially those prompting visual fatigue while experiencing the VR content. Finally, we present the results of the Hiedanranta's scans transformed into stereoscopic spherical animations.

Wide-field computational imaging of pathology slides using lens-free on-chip microscopy.

PubMed

Greenbaum, Alon; Zhang, Yibo; Feizi, Alborz; Chung, Ping-Luen; Luo, Wei; Kandukuri, Shivani R; Ozcan, Aydogan

2014-12-17

Optical examination of microscale features in pathology slides is one of the gold standards to diagnose disease. However, the use of conventional light microscopes is partially limited owing to their relatively high cost, bulkiness of lens-based optics, small field of view (FOV), and requirements for lateral scanning and three-dimensional (3D) focus adjustment. We illustrate the performance of a computational lens-free, holographic on-chip microscope that uses the transport-of-intensity equation, multi-height iterative phase retrieval, and rotational field transformations to perform wide-FOV imaging of pathology samples with comparable image quality to a traditional transmission lens-based microscope. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for mechanical focus adjustment and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. Using this lens-free on-chip microscope, we successfully imaged invasive carcinoma cells within human breast sections, Papanicolaou smears revealing a high-grade squamous intraepithelial lesion, and sickle cell anemia blood smears over a FOV of 20.5 mm(2). The resulting wide-field lens-free images had sufficient image resolution and contrast for clinical evaluation, as demonstrated by a pathologist's blinded diagnosis of breast cancer tissue samples, achieving an overall accuracy of ~99%. By providing high-resolution images of large-area pathology samples with 3D digital focus adjustment, lens-free on-chip microscopy can be useful in resource-limited and point-of-care settings. Copyright © 2014, American Association for the Advancement of Science.

PIFEX: An advanced programmable pipelined-image processor

NASA Technical Reports Server (NTRS)

Gennery, D. B.; Wilcox, B.

1985-01-01

PIFEX is a pipelined-image processor being built in the JPL Robotics Lab. It will operate on digitized raster-scanned images (at 60 frames per second for images up to about 300 by 400 and at lesser rates for larger images), performing a variety of operations simultaneously under program control. It thus is a powerful, flexible tool for image processing and low-level computer vision. It also has applications in other two-dimensional problems such as route planning for obstacle avoidance and the numerical solution of two-dimensional partial differential equations (although its low numerical precision limits its use in the latter field). The concept and design of PIFEX are described herein, and some examples of its use are given.

Detecting Edges in Images by Use of Fuzzy Reasoning

NASA Technical Reports Server (NTRS)

Dominguez, Jesus A.; Klinko, Steve

2003-01-01

A method of processing digital image data to detect edges includes the use of fuzzy reasoning. The method is completely adaptive and does not require any advance knowledge of an image. During initial processing of image data at a low level of abstraction, the nature of the data is indeterminate. Fuzzy reasoning is used in the present method because it affords an ability to construct useful abstractions from approximate, incomplete, and otherwise imperfect sets of data. Humans are able to make some sense of even unfamiliar objects that have imperfect high-level representations. It appears that to perceive unfamiliar objects or to perceive familiar objects in imperfect images, humans apply heuristic algorithms to understand the images

SSC Geopositional Assessment of the Advanced Wide Field Sensor

NASA Technical Reports Server (NTRS)

Ross, Kenton

2006-01-01

The geopositional accuracy of the standard geocorrected product from the Advanced Wide Field Sensor (AWiFS) was evaluated using digital orthophoto quarter quadrangles and other reference sources of similar accuracy. Images were analyzed from summer 2004 through spring 2005. Forty to fifty check points were collected manually per scene and analyzed to determine overall circular error, estimates of horizontal bias, and other systematic errors. Measured errors were somewhat higher than the specifications for the data, but they were consistent with the analysis of the distributing vendor.

1994 ASPRS/ACSM annual convention exposition. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-01-01

This report is Volume II of presented papers at the joint 1994 convention of the American Society for Photgrammetry and Remote Sensing and American Congress on Surveying and Mapping. Topic areas covered include the following: Data Base/GPS Issues; Survey Management Issues; Surveying computations; Surveying education; Digital mapping; global change, EOS and NALC issues; GPS issues; Battelle Research in Remote Sensing and in GIS; Advanced Image Processing;GIS Issues; Surveying and Geodesy Issues; water resource issues; Advanced applications of remote sensing; Landsat Pathfinder I.

Quantitative Secondary Electron Detector (QSED)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nayak, Subu; Joy, David C.

2013-12-31

Research is proposed to investigate the feasibility of applying recent advances in semiconductor technology to fabricate direct digital Quantitative Secondary Electron Detectors (QSED) for scanning electron microscopes (SEMs). If successful, commercial versions of the QSED would transform the SEM into a quantitative, metrological system with enhanced capabilities that, in turn, would broaden research horizons across industries. This project will be conducted in collaboration with Dr. David C Joy at the University of Tennessee, who has demonstrated limited (to the 1keV range) digital collection of the energy from backscattered signals in a SEM using a modified silicon drift detector. Several detectormore » configurations will be fabricated and tested for sensitivities, background noise reduction, DC offset elimination, and metrological capabilities (linearity, accuracy, etc.) against a set of commercially important performance criteria to ascertain concept feasibility. Once feasibility is proven, the solid state digital device array and its switching frequency will be scaled-up, in Phase II, to improve temporal resolution. If successful, this work will produce a crucial advancement in electron microscopy with wide-ranging applications. The following are key advantages anticipated from direct digital QSED: 1. High signal-to-noise ratio will improve SEM resolution in nano-scale, which is critical for dimensional metrology in any application. 2. Quantitative measurement will enhance process control and design validation in semiconductors, photo-voltaics, bio-medical devices and catalysts; and will improve accuracy in predicting the reliability and the lifecycle of materials across industries. 3. Video and dynamic-imaging capabilities will advance study in nano-scale phenomena in a variety of industries, including pharmaceutical and semiconductor materials. 4. Lower cost will make high-performing electron microscopes affordable to more researchers. 5. Compact size and ease of integration with imaging software will enable customers to retrofit and upgrade existing SEM equipment. ScienceTomorrow’s direct digital QSED concept has generated enthusiastic interest among a number of microscope makers, service companies, and microscope users. The company has offers of support from several companies. The roles these companies would play in supporting the project are described in the proposal. The proposed QSED advance sits squarely in the middle of ScienceTomorrow’s mission to provide next-generation technology solutions to today’s critical problems and, if successful, will further the company’s business strategy by launching an advanced, high-margin product that will enable the company and its partners to create at least 17 net-new jobs by the end of 2018.« less

IDEAL: Images Across Domains, Experiments, Algorithms and Learning

NASA Astrophysics Data System (ADS)

Ushizima, Daniela M.; Bale, Hrishikesh A.; Bethel, E. Wes; Ercius, Peter; Helms, Brett A.; Krishnan, Harinarayan; Grinberg, Lea T.; Haranczyk, Maciej; Macdowell, Alastair A.; Odziomek, Katarzyna; Parkinson, Dilworth Y.; Perciano, Talita; Ritchie, Robert O.; Yang, Chao

2016-11-01

Research across science domains is increasingly reliant on image-centric data. Software tools are in high demand to uncover relevant, but hidden, information in digital images, such as those coming from faster next generation high-throughput imaging platforms. The challenge is to analyze the data torrent generated by the advanced instruments efficiently, and provide insights such as measurements for decision-making. In this paper, we overview work performed by an interdisciplinary team of computational and materials scientists, aimed at designing software applications and coordinating research efforts connecting (1) emerging algorithms for dealing with large and complex datasets; (2) data analysis methods with emphasis in pattern recognition and machine learning; and (3) advances in evolving computer architectures. Engineering tools around these efforts accelerate the analyses of image-based recordings, improve reusability and reproducibility, scale scientific procedures by reducing time between experiments, increase efficiency, and open opportunities for more users of the imaging facilities. This paper describes our algorithms and software tools, showing results across image scales, demonstrating how our framework plays a role in improving image understanding for quality control of existent materials and discovery of new compounds.

Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications.

PubMed

Mudanyali, Onur; Tseng, Derek; Oh, Chulwoo; Isikman, Serhan O; Sencan, Ikbal; Bishara, Waheb; Oztoprak, Cetin; Seo, Sungkyu; Khademhosseini, Bahar; Ozcan, Aydogan

2010-06-07

Despite the rapid progress in optical imaging, most of the advanced microscopy modalities still require complex and costly set-ups that unfortunately limit their use beyond well equipped laboratories. In the meantime, microscopy in resource-limited settings has requirements significantly different from those encountered in advanced laboratories, and such imaging devices should be cost-effective, compact, light-weight and appropriately accurate and simple to be usable by minimally trained personnel. Furthermore, these portable microscopes should ideally be digitally integrated as part of a telemedicine network that connects various mobile health-care providers to a central laboratory or hospital. Toward this end, here we demonstrate a lensless on-chip microscope weighing approximately 46 grams with dimensions smaller than 4.2 cm x 4.2 cm x 5.8 cm that achieves sub-cellular resolution over a large field of view of approximately 24 mm(2). This compact and light-weight microscope is based on digital in-line holography and does not need any lenses, bulky optical/mechanical components or coherent sources such as lasers. Instead, it utilizes a simple light-emitting-diode (LED) and a compact opto-electronic sensor-array to record lensless holograms of the objects, which then permits rapid digital reconstruction of regular transmission or differential interference contrast (DIC) images of the objects. Because this lensless incoherent holographic microscope has orders-of-magnitude improved light collection efficiency and is very robust to mechanical misalignments it may offer a cost-effective tool especially for telemedicine applications involving various global health problems in resource limited settings.

3D printing application and numerical simulations in a fracture system

NASA Astrophysics Data System (ADS)

Yoon, H.; Martinez, M. J.

2017-12-01

The hydrogeological and mechanical properties in fractured and porous media are fundamental to predicting coupled multiphysics processes in the subsurface. Recent advances in experimental methods and multi-scale imaging capabilities have revolutionized our ability to quantitatively characterize geomaterials and digital counterparts are now routinely used for numerical simulations to characterize petrophysical and mechanical properties across scales. 3D printing is a very effective and creative technique that reproduce the digital images in a controlled way. For geoscience applications, 3D printing can be co-opted to print reproducible porous and fractured structures derived from CT-imaging of actual rocks and theoretical algorithms for experimental testing. In this work we used a stereolithography (SLA) method to create a single fracture network. The fracture in shale was first scanned using a microCT system and then the digital fracture network was printed into two parts and assembled. Aperture ranges from 0.3 to 1 mm. In particular, we discuss the design of single fracture network and the progress of printing practices to reproduce the fracture network system. Printed samples at different scales are used to measure the permeability and surface roughness. Various numerical simulations including (non-)reactive transport and multiphase flow cases are performed to study fluid flow characterization. We will also discuss the innovative advancement of 3D printing techniques applicable for coupled processes in the subsurface. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC., a wholly owned subsidiary of Honeywell International, Inc., for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA0003525.

Cartography for lunar exploration: 2008 status and mission plans

USGS Publications Warehouse

Kirk, R.L.; Archinal, B.A.; Gaddis, L.R.; Rosiek, M.R.; Chen, Jun; Jiang, Jie; Nayak, Shailesh

2008-01-01

The initial spacecraft exploration of the Moon in the 1960s-70s yielded extensive data, primarily in the form of film and television images, which were used to produce a large number of hardcopy maps by conventional techniques. A second era of exploration, beginning in the early 1990s, has produced digital data including global multispectral imagery and altimetry, from which a new generation of digital map products tied to a rapidly evolving global control network has been made. Efforts are also underway to scan the earlier hardcopy maps for online distribution and to digitize the film images so that modern processing techniques can be used to make high-resolution digital terrain models (DTMs) and image mosaics consistent with the current global control. The pace of lunar exploration is accelerating dramatically, with as many as eight new missions already launched or planned for the current decade. These missions, of which the most important for cartography are SMART-1 (Europe), Kaguya/SELENE (Japan), Chang'e-1 (China), Chandrayaan-1 (India), and Lunar Reconnaissance Orbiter (USA), will return a volume of data exceeding that of all previous lunar and planetary missions combined. Framing and scanner camera images, including multispectral and stereo data, hyperspectral images, synthetic aperture radar (SAR) images, and laser altimetry will all be collected, including, in most cases, multiple data sets of each type. Substantial advances in international standardization and cooperation, development of new and more efficient data processing methods, and availability of resources for processing and archiving will all be needed if the next generation of missions are to fulfill their potential for high-precision mapping of the Moon in support of subsequent exploration and scientific investigation.

Digital Rocks Portal: a Sustainable Platform for Data Management, Analysis and Remote Visualization of Volumetric Images of Porous Media

NASA Astrophysics Data System (ADS)

Prodanovic, M.; Esteva, M.; Ketcham, R. A.

2017-12-01

Nanometer to centimeter-scale imaging such as (focused ion beam) scattered electron microscopy, magnetic resonance imaging and X-ray (micro)tomography has since 1990s introduced 2D and 3D datasets of rock microstructure that allow investigation of nonlinear flow and mechanical phenomena on the length scales that are otherwise impervious to laboratory measurements. The numerical approaches that use such images produce various upscaled parameters required by subsurface flow and deformation simulators. All of this has revolutionized our knowledge about grain scale phenomena. However, a lack of data-sharing infrastructure among research groups makes it difficult to integrate different length scales. We have developed a sustainable, open and easy-to-use repository called the Digital Rocks Portal (https://www.digitalrocksportal.org), that (1) organizes images and related experimental measurements of different porous materials, (2) improves access to them for a wider community of engineering or geosciences researchers not necessarily trained in computer science or data analysis. Digital Rocks Portal (NSF EarthCube Grant 1541008) is the first repository for imaged porous microstructure data. It is implemented within the reliable, 24/7 maintained High Performance Computing Infrastructure supported by the Texas Advanced Computing Center (University of Texas at Austin). Long-term storage is provided through the University of Texas System Research Cyber-infrastructure initiative. We show how the data can be documented, referenced in publications via digital object identifiers (see Figure below for examples), visualized, searched for and linked to other repositories. We show recently implemented integration of the remote parallel visualization, bulk upload for large datasets as well as preliminary flow simulation workflow with the pore structures currently stored in the repository. We discuss the issues of collecting correct metadata, data discoverability and repository sustainability.

Fundus Photography in the 21st Century--A Review of Recent Technological Advances and Their Implications for Worldwide Healthcare.

PubMed

Panwar, Nishtha; Huang, Philemon; Lee, Jiaying; Keane, Pearse A; Chuan, Tjin Swee; Richhariya, Ashutosh; Teoh, Stephen; Lim, Tock Han; Agrawal, Rupesh

2016-03-01

The introduction of fundus photography has impacted retinal imaging and retinal screening programs significantly. Fundus cameras play a vital role in addressing the cause of preventive blindness. More attention is being turned to developing countries, where infrastructure and access to healthcare are limited. One of the major limitations for tele-ophthalmology is restricted access to the office-based fundus camera. Recent advances in access to telecommunications coupled with introduction of portable cameras and smartphone-based fundus imaging systems have resulted in an exponential surge in available technologies for portable fundus photography. Retinal cameras in the near future would have to cater to these needs by featuring a low-cost, portable design with automated controls and digitalized images with Web-based transfer. In this review, we aim to highlight the advances of fundus photography for retinal screening as well as discuss the advantages, disadvantages, and implications of the various technologies that are currently available.

Fundus Photography in the 21st Century—A Review of Recent Technological Advances and Their Implications for Worldwide Healthcare

PubMed Central

Panwar, Nishtha; Huang, Philemon; Lee, Jiaying; Keane, Pearse A.; Chuan, Tjin Swee; Richhariya, Ashutosh; Teoh, Stephen; Lim, Tock Han

2016-01-01

Abstract Background: The introduction of fundus photography has impacted retinal imaging and retinal screening programs significantly. Literature Review: Fundus cameras play a vital role in addressing the cause of preventive blindness. More attention is being turned to developing countries, where infrastructure and access to healthcare are limited. One of the major limitations for tele-ophthalmology is restricted access to the office-based fundus camera. Results: Recent advances in access to telecommunications coupled with introduction of portable cameras and smartphone-based fundus imaging systems have resulted in an exponential surge in available technologies for portable fundus photography. Retinal cameras in the near future would have to cater to these needs by featuring a low-cost, portable design with automated controls and digitalized images with Web-based transfer. Conclusions: In this review, we aim to highlight the advances of fundus photography for retinal screening as well as discuss the advantages, disadvantages, and implications of the various technologies that are currently available. PMID:26308281

Discrete Walsh Hadamard transform based visible watermarking technique for digital color images

NASA Astrophysics Data System (ADS)

Santhi, V.; Thangavelu, Arunkumar

2011-10-01

As the size of the Internet is growing enormously the illegal manipulation of digital multimedia data become very easy with the advancement in technology tools. In order to protect those multimedia data from unauthorized access the digital watermarking system is used. In this paper a new Discrete walsh Hadamard Transform based visible watermarking system is proposed. As the watermark is embedded in transform domain, the system is robust to many signal processing attacks. Moreover in this proposed method the watermark is embedded in tiling manner in all the range of frequencies to make it robust to compression and cropping attack. The robustness of the algorithm is tested against noise addition, cropping, compression, Histogram equalization and resizing attacks. The experimental results show that the algorithm is robust to common signal processing attacks and the observed peak signal to noise ratio (PSNR) of watermarked image is varying from 20 to 30 db depends on the size of the watermark.

Digital Rocks Portal: Preservation, Sharing, Remote Visualization and Automated Analysis of Imaged Datasets

NASA Astrophysics Data System (ADS)

Prodanovic, M.; Esteva, M.; Ketcham, R. A.; Hanlon, M.; Pettengill, M.; Ranganath, A.; Venkatesh, A.

2016-12-01

Due to advances in imaging modalities such as X-ray microtomography and scattered electron microscopy, 2D and 3D imaged datasets of rock microstructure on nanometer to centimeter length scale allow investigation of nonlinear flow and mechanical phenomena using numerical approaches. This in turn produces various upscaled parameters required by subsurface flow and deformation simulators. However, a single research group typically specializes in an imaging modality and/or related modeling on a single length scale, and lack of data-sharing infrastructure makes it difficult to integrate different length scales. We developed a sustainable, open and easy-to-use repository called the Digital Rocks Portal (http://www.digitalrocksportal.org), that (1) organizes images and related experimental measurements of different porous materials, (2) improves access to them for a wider community of geosciences or engineering researchers not necessarily trained in computer science or data analysis. Our objective is to enable scientific inquiry and engineering decisions founded on a data-driven basis. We show how the data loaded in the portal can be documented, referenced in publications via digital object identifiers, visualize and linked to other repositories. We then show preliminary results on integrating remote parallel visualization and flow simulation workflow with the pore structures currently stored in the repository. We finally discuss the issues of collecting correct metadata, data discoverability and repository sustainability. This is the first repository for this particular data, but is part of the wider ecosystem of geoscience data and model cyber-infrastructure called "Earthcube" (http://earthcube.org/) sponsored by National Science Foundation. For data sustainability and continuous access, the portal is implemented within the reliable, 24/7 maintained High Performance Computing Infrastructure supported by the Texas Advanced Computing Center (TACC) at the University of Texas at Austin. Long-term storage is provided through the University of Texas System Research Cyber-infrastructure initiative.

Digital Camera Control for Faster Inspection

NASA Technical Reports Server (NTRS)

Brown, Katharine; Siekierski, James D.; Mangieri, Mark L.; Dekome, Kent; Cobarruvias, John; Piplani, Perry J.; Busa, Joel

2009-01-01

Digital Camera Control Software (DCCS) is a computer program for controlling a boom and a boom-mounted camera used to inspect the external surface of a space shuttle in orbit around the Earth. Running in a laptop computer in the space-shuttle crew cabin, DCCS commands integrated displays and controls. By means of a simple one-button command, a crewmember can view low- resolution images to quickly spot problem areas and can then cause a rapid transition to high- resolution images. The crewmember can command that camera settings apply to a specific small area of interest within the field of view of the camera so as to maximize image quality within that area. DCCS also provides critical high-resolution images to a ground screening team, which analyzes the images to assess damage (if any); in so doing, DCCS enables the team to clear initially suspect areas more quickly than would otherwise be possible and further saves time by minimizing the probability of re-imaging of areas already inspected. On the basis of experience with a previous version (2.0) of the software, the present version (3.0) incorporates a number of advanced imaging features that optimize crewmember capability and efficiency.

Influence of study design on digital pathology image quality evaluation: the need to define a clinical task

PubMed Central

Platiša, Ljiljana; Brantegem, Leen Van; Kumcu, Asli; Ducatelle, Richard; Philips, Wilfried

2017-01-01

Abstract. Despite the current rapid advance in technologies for whole slide imaging, there is still no scientific consensus on the recommended methodology for image quality assessment of digital pathology slides. For medical images in general, it has been recommended to assess image quality in terms of doctors’ success rates in performing a specific clinical task while using the images (clinical image quality, cIQ). However, digital pathology is a new modality, and already identifying the appropriate task is difficult. In an alternative common approach, humans are asked to do a simpler task such as rating overall image quality (perceived image quality, pIQ), but that involves the risk of nonclinically relevant findings due to an unknown relationship between the pIQ and cIQ. In this study, we explored three different experimental protocols: (1) conducting a clinical task (detecting inclusion bodies), (2) rating image similarity and preference, and (3) rating the overall image quality. Additionally, within protocol 1, overall quality ratings were also collected (task-aware pIQ). The experiments were done by diagnostic veterinary pathologists in the context of evaluating the quality of hematoxylin and eosin-stained digital pathology slides of animal tissue samples under several common image alterations: additive noise, blurring, change in gamma, change in color saturation, and JPG compression. While the size of our experiments was small and prevents drawing strong conclusions, the results suggest the need to define a clinical task. Importantly, the pIQ data collected under protocols 2 and 3 did not always rank the image alterations the same as their cIQ from protocol 1, warning against using conventional pIQ to predict cIQ. At the same time, there was a correlation between the cIQ and task-aware pIQ ratings from protocol 1, suggesting that the clinical experiment context (set by specifying the clinical task) may affect human visual attention and bring focus to their criteria of image quality. Further research is needed to assess whether and for which purposes (e.g., preclinical testing) task-aware pIQ ratings could substitute cIQ for a given clinical task. PMID:28653011

Influence of study design on digital pathology image quality evaluation: the need to define a clinical task.

PubMed

Platiša, Ljiljana; Brantegem, Leen Van; Kumcu, Asli; Ducatelle, Richard; Philips, Wilfried

2017-04-01

Despite the current rapid advance in technologies for whole slide imaging, there is still no scientific consensus on the recommended methodology for image quality assessment of digital pathology slides. For medical images in general, it has been recommended to assess image quality in terms of doctors' success rates in performing a specific clinical task while using the images (clinical image quality, cIQ). However, digital pathology is a new modality, and already identifying the appropriate task is difficult. In an alternative common approach, humans are asked to do a simpler task such as rating overall image quality (perceived image quality, pIQ), but that involves the risk of nonclinically relevant findings due to an unknown relationship between the pIQ and cIQ. In this study, we explored three different experimental protocols: (1) conducting a clinical task (detecting inclusion bodies), (2) rating image similarity and preference, and (3) rating the overall image quality. Additionally, within protocol 1, overall quality ratings were also collected (task-aware pIQ). The experiments were done by diagnostic veterinary pathologists in the context of evaluating the quality of hematoxylin and eosin-stained digital pathology slides of animal tissue samples under several common image alterations: additive noise, blurring, change in gamma, change in color saturation, and JPG compression. While the size of our experiments was small and prevents drawing strong conclusions, the results suggest the need to define a clinical task. Importantly, the pIQ data collected under protocols 2 and 3 did not always rank the image alterations the same as their cIQ from protocol 1, warning against using conventional pIQ to predict cIQ. At the same time, there was a correlation between the cIQ and task-aware pIQ ratings from protocol 1, suggesting that the clinical experiment context (set by specifying the clinical task) may affect human visual attention and bring focus to their criteria of image quality. Further research is needed to assess whether and for which purposes (e.g., preclinical testing) task-aware pIQ ratings could substitute cIQ for a given clinical task.

Blue Beaufort Sea Ice from Operation IceBridge

NASA Image and Video Library

2017-12-08

Mosaic image of sea ice in the Beaufort Sea created by the Digital Mapping System (DMS) instrument aboard the IceBridge P-3B. The dark area in the middle of the image is open water seen through a lead, or opening, in the ice. Light blue areas are thick sea ice and dark blue areas are thinner ice formed as water in the lead refreezes. Leads are formed when cracks develop in sea ice as it moves in response to wind and ocean currents. DMS uses a modified digital SLR camera that points down through a window in the underside of the plane, capturing roughly one frame per second. These images are then combined into an image mosaic using specialized computer software. Credit: NASA/DMS NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Photogrammetry for documentation of vehicle deformations--a tool in a system for advanced accident data collection.

PubMed

Kullgren, A; Lie, A; Tingvall, C

1994-02-01

Vehicle deformations are important sources for information about the performance of safety systems. Photogrammetry has developed vastly under recent years. In this study modern photogrammetrical methods have been used for vehicle deformation analysis. The study describes the equipment for documentation and recording in the field (semi-metric camera), and a system for photogrammetrical measurements of the images in laboratory environment (personal computer and digitizing tablet). The material used is approximately 500 collected and measured cases. The study shows that the reliability is high and that accuracies around 15mm can be achieved even if the equipment and routines used are relatively simple. The effects of further development using video cameras for data capture and digital images for measurements are discussed.

Advances in optical information processing IV; Proceedings of the Meeting, Orlando, FL, Apr. 18-20, 1990

NASA Astrophysics Data System (ADS)

Pape, Dennis R.

1990-09-01

The present conference discusses topics in optical image processing, optical signal processing, acoustooptic spectrum analyzer systems and components, and optical computing. Attention is given to tradeoffs in nonlinearly recorded matched filters, miniature spatial light modulators, detection and classification using higher-order statistics of optical matched filters, rapid traversal of an image data base using binary synthetic discriminant filters, wideband signal processing for emitter location, an acoustooptic processor for autonomous SAR guidance, and sampling of Fresnel transforms. Also discussed are an acoustooptic RF signal-acquisition system, scanning acoustooptic spectrum analyzers, the effects of aberrations on acoustooptic systems, fast optical digital arithmetic processors, information utilization in analog and digital processing, optical processors for smart structures, and a self-organizing neural network for unsupervised learning.

Brazilian young dental practitioners' use and acceptance of digital radiographic examinations

PubMed Central

de Faria Vasconcelos, Karla; do Nascimento, Eduarda Helena Leandro; Oliveira, Matheus Lima; Freitas, Deborah Queiroz; Haiter-Neto, Francisco

2016-01-01

Purpose The aim of this study was to investigate the use and acceptance of digital radiographic examinations by Brazilian dental practitioners in daily practice and to evaluate the advances that have occurred over the past 5 years. Materials and Methods Dental practitioners enrolled in extension courses at the Piracicaba Dental School, University of Campinas, Brazil, responded to a self-administered questionnaire in the years 2011 and 2015. They were asked about sociodemographic factors and their knowledge and use of digital radiographic examinations. Descriptive analysis was performed, as well as the chi-square and Fisher exact tests, with a significance level of 5% (α=0.05). Results A total of 181 participants responded to the questionnaire in the years 2011 and 2015. Most of the respondents worked in private practice, had graduated within the last 5 years, and were between 20 and 30 years old. In 2011, 55.6% of respondents reported having ever used digital radiographic examinations, while in 2015 this number increased significantly to 85.4% (p<.0001), out of which 71.4% preferred it to conventional images. Moreover, 21.4% of respondents reported having used digital radiographic examinations for more than 3 years. A significant increase in use of intraoral digital radiography (p=0.0316) was observed in 2015. In both years, image quality and high cost were indicated, respectively, as the main advantage and disadvantage of digital radiographic examinations. Conclusion This study showed that digital radiology has become more common in Brazil over the past 5 years. Most of the Brazilian dental practitioners evaluated in 2015 used digital radiographic examinations. PMID:28035301

Brazilian young dental practitioners' use and acceptance of digital radiographic examinations.

PubMed

Rovaris, Karla; de Faria Vasconcelos, Karla; do Nascimento, Eduarda Helena Leandro; Oliveira, Matheus Lima; Freitas, Deborah Queiroz; Haiter-Neto, Francisco

2016-12-01

The aim of this study was to investigate the use and acceptance of digital radiographic examinations by Brazilian dental practitioners in daily practice and to evaluate the advances that have occurred over the past 5 years. Dental practitioners enrolled in extension courses at the Piracicaba Dental School, University of Campinas, Brazil, responded to a self-administered questionnaire in the years 2011 and 2015. They were asked about sociodemographic factors and their knowledge and use of digital radiographic examinations. Descriptive analysis was performed, as well as the chi-square and Fisher exact tests, with a significance level of 5% (α=0.05). A total of 181 participants responded to the questionnaire in the years 2011 and 2015. Most of the respondents worked in private practice, had graduated within the last 5 years, and were between 20 and 30 years old. In 2011, 55.6% of respondents reported having ever used digital radiographic examinations, while in 2015 this number increased significantly to 85.4% (p<.0001), out of which 71.4% preferred it to conventional images. Moreover, 21.4% of respondents reported having used digital radiographic examinations for more than 3 years. A significant increase in use of intraoral digital radiography (p=0.0316) was observed in 2015. In both years, image quality and high cost were indicated, respectively, as the main advantage and disadvantage of digital radiographic examinations. This study showed that digital radiology has become more common in Brazil over the past 5 years. Most of the Brazilian dental practitioners evaluated in 2015 used digital radiographic examinations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Y.; Tobias, B.; Chang, Y. -T.

Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. The microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These also have the potential to greatly advance microwavemore » fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfven eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today's most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.« less

Semantic Integrative Digital Pathology: Insights into Microsemiological Semantics and Image Analysis Scalability.

PubMed

Racoceanu, Daniel; Capron, Frédérique

2016-01-01

Being able to provide a traceable and dynamic second opinion has become an ethical priority for patients and health care professionals in modern computer-aided medicine. In this perspective, a semantic cognitive virtual microscopy approach has been recently initiated, the MICO project, by focusing on cognitive digital pathology. This approach supports the elaboration of pathology-compliant daily protocols dedicated to breast cancer grading, in particular mitotic counts and nuclear atypia. A proof of concept has thus been elaborated, and an extension of these approaches is now underway in a collaborative digital pathology framework, the FlexMIm project. As important milestones on the way to routine digital pathology, a series of pioneer international benchmarking initiatives have been launched for mitosis detection (MITOS), nuclear atypia grading (MITOS-ATYPIA) and glandular structure detection (GlaS), some of the fundamental grading components in diagnosis and prognosis. These initiatives allow envisaging a consolidated validation referential database for digital pathology in the very near future. This reference database will need coordinated efforts from all major teams working in this area worldwide, and it will certainly represent a critical bottleneck for the acceptance of all future imaging modules in clinical practice. In line with recent advances in molecular imaging and genetics, keeping the microscopic modality at the core of future digital systems in pathology is fundamental to insure the acceptance of these new technologies, as well as for a deeper systemic, structured comprehension of the pathologies. After all, at the scale of routine whole-slide imaging (WSI; ∼0.22 µm/pixel), the microscopic image represents a structured 'genomic cluster', enabling a naturally structured support for integrative digital pathology approaches. In order to accelerate and structure the integration of this heterogeneous information, a major effort is and will continue to be devoted to morphological microsemiology (microscopic morphology semantics). Besides insuring the traceability of the results (second opinion) and supporting the orchestration of high-content image analysis modules, the role of semantics will be crucial for the correlation between digital pathology and noninvasive medical imaging modalities. In addition, semantics has an important role in modelling the links between traditional microscopy and recent label-free technologies. The massive amount of visual data is challenging and represents a characteristic intrinsic to digital pathology. The design of an operational integrative microscopy framework needs to focus on scalable multiscale imaging formalism. In this sense, we prospectively consider some of the most recent scalable methodologies adapted to digital pathology as marked point processes for nuclear atypia and point-set mathematical morphology for architecture grading. To orchestrate this scalable framework, semantics-based WSI management (analysis, exploration, indexing, retrieval and report generation support) represents an important means towards approaches to integrating big data into biomedicine. This insight reflects our vision through an instantiation of essential bricks of this type of architecture. The generic approach introduced here is applicable to a number of challenges related to molecular imaging, high-content image management and, more generally, bioinformatics. © 2016 S. Karger AG, Basel.

Real-time 3D adaptive filtering for portable imaging systems

NASA Astrophysics Data System (ADS)

Bockenbach, Olivier; Ali, Murtaza; Wainwright, Ian; Nadeski, Mark

2015-03-01

Portable imaging devices have proven valuable for emergency medical services both in the field and hospital environments and are becoming more prevalent in clinical settings where the use of larger imaging machines is impractical. 3D adaptive filtering is one of the most advanced techniques aimed at noise reduction and feature enhancement, but is computationally very demanding and hence often not able to run with sufficient performance on a portable platform. In recent years, advanced multicore DSPs have been introduced that attain high processing performance while maintaining low levels of power dissipation. These processors enable the implementation of complex algorithms like 3D adaptive filtering, improving the image quality of portable medical imaging devices. In this study, the performance of a 3D adaptive filtering algorithm on a digital signal processor (DSP) is investigated. The performance is assessed by filtering a volume of size 512x256x128 voxels sampled at a pace of 10 MVoxels/sec.

Interpretation of digital breast tomosynthesis: preliminary study on comparison with picture archiving and communication system (PACS) and dedicated workstation.

PubMed

Kim, Young Seon; Chang, Jung Min; Yi, Ann; Shin, Sung Ui; Lee, Myung Eun; Kim, Won Hwa; Cho, Nariya; Moon, Woo Kyung

2017-08-01

To compare the diagnostic accuracy and efficiency in the interpretation of digital breast tomosynthesis (DBT) images using a picture archiving and communication system (PACS) and a dedicated workstation. 97 DBT images obtained for screening or diagnostic purposes were stored in both a workstation and a PACS and evaluated in combination with digital mammography by three independent radiologists retrospectively. Breast Imaging-Reporting and Data System final assessments and likelihood of malignancy (%) were assigned and the interpretation time when using the workstation and PACS was recorded. Receiver operating characteristic curve analysis, sensitivities and specificities were compared with histopathological examination and follow-up data as a reference standard. Area under the receiver operating characteristic curve values for cancer detection (0.839 vs 0.815, p = 0.6375) and sensitivity (81.8% vs 75.8%, p = 0.2188) showed no statistically significant differences between the workstation and PACS. However, specificity was significantly higher when analysing on the workstation than when using PACS (83.7% vs 76.9%, p = 0.009). When evaluating DBT images using PACS, only one case was deemed necessary to be reanalysed using the workstation. The mean time to interpret DBT images on PACS (1.68 min/case) was significantly longer than that to interpret on the workstation (1.35 min/case) (p < 0.0001). Interpretation of DBT images using PACS showed comparable diagnostic performance to a dedicated workstation, even though it required a longer reading time. Advances in knowledge: Interpretation of DBT images using PACS is an alternative to evaluate the images when a dedicated workstation is not available.

Development of a prototype chest digital tomosynthesis R/F system

NASA Astrophysics Data System (ADS)

Choi, Sunghoon; Lee, Haenghwa; Lee, Donghoon; Choi, Seungyeon; Shin, Jungwook; Jang, Woojin; Seo, Chang-Woo; Kim, Hee-Joung

2017-03-01

Digital tomosynthesis has an advantage of low radiation dose compared to conventional computed tomography (CT) by utilizing small number of projections ( 80) acquired over a limited angular range. It can produce 3D volumetric data although they may have some artifacts due to incomplete sampling. Based upon these attractive merits, we developed a prototype digital tomosynthesis R/F system especially for the purpose of applications in chest imaging. Prototype chest digital tomosynthesis (CDT) R/F system contains an X-ray tube with high power R/F pulse generator, flat-panel detector, R/F table, electromechanical radiographic subsystems including precise motor controller, and a reconstruction server. For image reconstruction, users could select the reconstruction option between analytic and iterative methods. Reconstructed images of Catphan700 and LUNGMAN phantoms clearly and rapidly described the internal structures of the phantoms using graphics processing unit (GPU) programming. Contrast-to-noise ratio (CNR) values of the CTP682 module was higher in images using the simultaneous algebraic reconstruction technique (SART) than those using filtered backprojection (FBP) for all materials by factors of 2.60, 3.78, 5.50, 2.30, 3.70, and 2.52 for air, lung foam, low density polyethylene (LDPE), Delrin (acetal homopolymer resin), bone 50% (hydroxyapatite), and Teflon, respectively. Total elapsed times for producing 3D volume were 2.92 sec and 86.29 sec on average for FBP and SART (20 iterations), respectively. The times required for reconstruction were clinically feasible. Moreover, the total radiation dose from the system (5.68 mGy) could demonstrate a significant lowered radiation dose compared to conventional chest CT scan. Consequently, our prototype tomosynthesis R/F system represents an important advance in digital tomosynthesis applications.

Processing and analysis of commercial satellite image data of the nuclear accident near Chernobyl, U. S. S. R

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sadowski, F.G.; Covington, S.J.

1987-01-01

Advanced digital processing techniques were applied to Landsat-5 Thematic Mapper (TM) data and SPOT high-resolution visible (HRV) panchromatic data to maximize the utility of images of a nuclear power plant emergency at Chernobyl in the Soviet Ukraine. The results of the data processing and analysis illustrate the spectral and spatial capabilities of the two sensor systems and provide information about the severity and duration of the events occurring at the power plant site.

Review of passive-blind detection in digital video forgery based on sensing and imaging techniques

NASA Astrophysics Data System (ADS)

Tao, Junjie; Jia, Lili; You, Ying

2016-01-01

Advances in digital video compression and IP communication technologies raised new issues and challenges concerning the integrity and authenticity of surveillance videos. It is so important that the system should ensure that once recorded, the video cannot be altered; ensuring the audit trail is intact for evidential purposes. This paper gives an overview of passive techniques of Digital Video Forensics which are based on intrinsic fingerprints inherent in digital surveillance videos. In this paper, we performed a thorough research of literatures relevant to video manipulation detection methods which accomplish blind authentications without referring to any auxiliary information. We presents review of various existing methods in literature, and much more work is needed to be done in this field of video forensics based on video data analysis and observation of the surveillance systems.

Volumetric breast density measurement: sensitivity analysis of a relative physics approach

PubMed Central

Lau, Susie; Abdul Aziz, Yang Faridah

2016-01-01

Objective: To investigate the sensitivity and robustness of a volumetric breast density (VBD) measurement system to errors in the imaging physics parameters including compressed breast thickness (CBT), tube voltage (kVp), filter thickness, tube current-exposure time product (mAs), detector gain, detector offset and image noise. Methods: 3317 raw digital mammograms were processed with Volpara® (Matakina Technology Ltd, Wellington, New Zealand) to obtain fibroglandular tissue volume (FGV), breast volume (BV) and VBD. Errors in parameters including CBT, kVp, filter thickness and mAs were simulated by varying them in the Digital Imaging and Communications in Medicine (DICOM) tags of the images up to ±10% of the original values. Errors in detector gain and offset were simulated by varying them in the Volpara configuration file up to ±10% from their default values. For image noise, Gaussian noise was generated and introduced into the original images. Results: Errors in filter thickness, mAs, detector gain and offset had limited effects on FGV, BV and VBD. Significant effects in VBD were observed when CBT, kVp, detector offset and image noise were varied (p < 0.0001). Maximum shifts in the mean (1.2%) and median (1.1%) VBD of the study population occurred when CBT was varied. Conclusion: Volpara was robust to expected clinical variations, with errors in most investigated parameters giving limited changes in results, although extreme variations in CBT and kVp could lead to greater errors. Advances in knowledge: Despite Volpara's robustness, rigorous quality control is essential to keep the parameter errors within reasonable bounds. Volpara appears robust within those bounds, albeit for more advanced applications such as tracking density change over time, it remains to be seen how accurate the measures need to be. PMID:27452264

Preferred color correction for digital LCD TVs

NASA Astrophysics Data System (ADS)

Kim, Kyoung Tae; Kim, Choon-Woo; Ahn, Ji-Young; Kang, Dong-Woo; Shin, Hyun-Ho

2009-01-01

Instead of colorimetirc color reproduction, preferred color correction is applied for digital TVs to improve subjective image quality. First step of the preferred color correction is to survey the preferred color coordinates of memory colors. This can be achieved by the off-line human visual tests. Next step is to extract pixels of memory colors representing skin, grass and sky. For the detected pixels, colors are shifted towards the desired coordinates identified in advance. This correction process may result in undesirable contours on the boundaries between the corrected and un-corrected areas. For digital TV applications, the process of extraction and correction should be applied in every frame of the moving images. This paper presents a preferred color correction method in LCH color space. Values of chroma and hue are corrected independently. Undesirable contours on the boundaries of correction are minimized. The proposed method change the coordinates of memory color pixels towards the target color coordinates. Amount of correction is determined based on the averaged coordinate of the extracted pixels. The proposed method maintains the relative color difference within memory color areas. Performance of the proposed method is evaluated using the paired comparison. Results of experiments indicate that the proposed method can reproduce perceptually pleasing images to viewers.

Post-processing methods of rendering and visualizing 3-D reconstructed tomographic images

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wong, S.T.C.

The purpose of this presentation is to discuss the computer processing techniques of tomographic images, after they have been generated by imaging scanners, for volume visualization. Volume visualization is concerned with the representation, manipulation, and rendering of volumetric data. Since the first digital images were produced from computed tomography (CT) scanners in the mid 1970s, applications of visualization in medicine have expanded dramatically. Today, three-dimensional (3D) medical visualization has expanded from using CT data, the first inherently digital source of 3D medical data, to using data from various medical imaging modalities, including magnetic resonance scanners, positron emission scanners, digital ultrasound,more » electronic and confocal microscopy, and other medical imaging modalities. We have advanced from rendering anatomy to aid diagnosis and visualize complex anatomic structures to planning and assisting surgery and radiation treatment. New, more accurate and cost-effective procedures for clinical services and biomedical research have become possible by integrating computer graphics technology with medical images. This trend is particularly noticeable in current market-driven health care environment. For example, interventional imaging, image-guided surgery, and stereotactic and visualization techniques are now stemming into surgical practice. In this presentation, we discuss only computer-display-based approaches of volumetric medical visualization. That is, we assume that the display device available is two-dimensional (2D) in nature and all analysis of multidimensional image data is to be carried out via the 2D screen of the device. There are technologies such as holography and virtual reality that do provide a {open_quotes}true 3D screen{close_quotes}. To confine the scope, this presentation will not discuss such approaches.« less

A New Presentation and Exploration of Human Cerebral Vasculature Correlated with Surface and Sectional Neuroanatomy

ERIC Educational Resources Information Center

Nowinski, Wieslaw L.; Thirunavuukarasuu, Arumugam; Volkau, Ihar; Marchenko, Yevgen; Aminah, Bivi; Gelas, Arnaud; Huang, Su; Lee, Looi Chow; Liu, Jimin; Ng, Ting Ting; Nowinska, Natalia G.; Qian, Guoyu Yu; Puspitasari, Fiftarina; Runge, Val M.

2009-01-01

The increasing complexity of human body models enabled by advances in diagnostic imaging, computing, and growing knowledge calls for the development of a new generation of systems for intelligent exploration of these models. Here, we introduce a novel paradigm for the exploration of digital body models illustrating cerebral vasculature. It enables…

Development of CMOS Active Pixel Image Sensors for Low Cost Commercial Applications

NASA Technical Reports Server (NTRS)

Gee, R.; Kemeny, S.; Kim, Q.; Mendis, S.; Nakamura, J.; Nixon, R.; Ortiz, M.; Pain, B.; Staller, C.; Zhou, Z;

Structure and properties of clinical coralline implants measured via 3D imaging and analysis.

PubMed

Knackstedt, Mark Alexander; Arns, Christoph H; Senden, Tim J; Gross, Karlis

2006-05-01

The development and design of advanced porous materials for biomedical applications requires a thorough understanding of how material structure impacts on mechanical and transport properties. This paper illustrates a 3D imaging and analysis study of two clinically proven coral bone graft samples (Porites and Goniopora). Images are obtained from X-ray micro-computed tomography (micro-CT) at a resolution of 16.8 microm. A visual comparison of the two images shows very different structure; Porites has a homogeneous structure and consistent pore size while Goniopora has a bimodal pore size and a strongly disordered structure. A number of 3D structural characteristics are measured directly on the images including pore volume-to-surface-area, pore and solid size distributions, chord length measurements and tortuosity. Computational results made directly on the digitized tomographic images are presented for the permeability, diffusivity and elastic modulus of the coral samples. The results allow one to quantify differences between the two samples. 3D digital analysis can provide a more thorough assessment of biomaterial structure including the pore wall thickness, local flow, mechanical properties and diffusion pathways. We discuss the implications of these results to the development of optimal scaffold design for tissue ingrowth.

Multi-Contrast Imaging and Digital Refocusing on a Mobile Microscope with a Domed LED Array.

PubMed

Phillips, Zachary F; D'Ambrosio, Michael V; Tian, Lei; Rulison, Jared J; Patel, Hurshal S; Sadras, Nitin; Gande, Aditya V; Switz, Neil A; Fletcher, Daniel A; Waller, Laura

2015-01-01

We demonstrate the design and application of an add-on device for improving the diagnostic and research capabilities of CellScope--a low-cost, smartphone-based point-of-care microscope. We replace the single LED illumination of the original CellScope with a programmable domed LED array. By leveraging recent advances in computational illumination, this new device enables simultaneous multi-contrast imaging with brightfield, darkfield, and phase imaging modes. Further, we scan through illumination angles to capture lightfield datasets, which can be used to recover 3D intensity and phase images without any hardware changes. This digital refocusing procedure can be used for either 3D imaging or software-only focus correction, reducing the need for precise mechanical focusing during field experiments. All acquisition and processing is performed on the mobile phone and controlled through a smartphone application, making the computational microscope compact and portable. Using multiple samples and different objective magnifications, we demonstrate that the performance of our device is comparable to that of a commercial microscope. This unique device platform extends the field imaging capabilities of CellScope, opening up new clinical and research possibilities.

Multi-Contrast Imaging and Digital Refocusing on a Mobile Microscope with a Domed LED Array

PubMed Central

Phillips, Zachary F.; D'Ambrosio, Michael V.; Tian, Lei; Rulison, Jared J.; Patel, Hurshal S.; Sadras, Nitin; Gande, Aditya V.; Switz, Neil A.; Fletcher, Daniel A.; Waller, Laura

2015-01-01

We demonstrate the design and application of an add-on device for improving the diagnostic and research capabilities of CellScope—a low-cost, smartphone-based point-of-care microscope. We replace the single LED illumination of the original CellScope with a programmable domed LED array. By leveraging recent advances in computational illumination, this new device enables simultaneous multi-contrast imaging with brightfield, darkfield, and phase imaging modes. Further, we scan through illumination angles to capture lightfield datasets, which can be used to recover 3D intensity and phase images without any hardware changes. This digital refocusing procedure can be used for either 3D imaging or software-only focus correction, reducing the need for precise mechanical focusing during field experiments. All acquisition and processing is performed on the mobile phone and controlled through a smartphone application, making the computational microscope compact and portable. Using multiple samples and different objective magnifications, we demonstrate that the performance of our device is comparable to that of a commercial microscope. This unique device platform extends the field imaging capabilities of CellScope, opening up new clinical and research possibilities. PMID:25969980

Application of the advanced communications technology satellite for teleradiology and telemedicine

NASA Astrophysics Data System (ADS)

Stewart, Brent K.; Carter, Stephen J.; Rowberg, Alan H.

1995-05-01

The authors have an in-kind grant from NASA to investigate the application of the Advanced Communications Technology Satellite (ACTS) to teleradiology and telemedicine using the JPL developed ACTS Mobile Terminal (AMT) uplink. This experiment involves the transmission of medical imagery (CT, MR, CR, US and digitized radiographs including mammograms), between the ACTS/AMT and the University of Washington. This is accomplished by locating the AMT experiment van in various locations throughout Washington state, Idaho, Montana, Oregon and Hawaii. The medical images are transmitted from the ACTS to the downlink at the NASA Lewis Research Center (LeRC) in Cleveland, Ohio, consisting of AMT equipment and the high burst rate-link evaluation terminal (HBR-LET). These images are then routed from LeRC to the University of Washington School of Medicine (UWSoM) through the Internet and public switched Integrated Serviced Digital Network (ISDN). Once images arrive in the UW Radiology Department, they are reviewed using both video monitor softcopy and laser-printed hardcopy. Compressed video teleconferencing and transmission of real-time ultrasound video between the AMT van and the UWSoM are also tested. Image quality comparisons are made using both subjective diagnostic criteria and quantitative engineering analysis. Evaluation is performed during various weather conditions (including rain to assess rain fade compensation algorithms). Compression techniques also are tested to evaluate their effects on image quality, allowing further evaluation of portable teleradiology/telemedicine at lower data rates and providing useful information for additional applications (e.g., smaller remote units, shipboard, emergency disaster, etc.). The medical images received at the UWSoM over the ACTS are directly evaluated against the original digital images. The project demonstrates that a portable satellite-land connection can provide subspecialty consultation and education for rural and remote areas. The experiment is divided into three phases. Using the ACTS fixed-hopping beam, phase one involves testing connection of the AMT to medical imaging equipment and image transmission in various climates in western and eastern Washington state. The second phase involves satellite relay transmissions between the Inmarsat satellite and the ACTS/AMT through a ground station in Hawaii for medical imagery originating from either Okinawa, Japan or Kwajalein, in the Pacific. The third phase involves extended use of the ACTS steerable beam in Washington state, Idaho, Montanan and Oregon.

Picture archiving and communication in radiology.

PubMed

Napoli, Marzia; Nanni, Marinella; Cimarra, Stefania; Crisafulli, Letizia; Campioni, Paolo; Marano, Pasquale

2003-01-01

After over 80 years of exclusive archiving of radiologic films, at present, in Radiology, digital archiving is increasingly gaining ground. Digital archiving allows a considerable reduction in costs and space saving, but most importantly, immediate or remote consultation of all examinations and reports in the hospital clinical wards, is feasible. The RIS system, in this case, is the starting point of the process of electronic archiving which however is the task of PACS. The latter can be used as radiologic archive in accordance with the law provided that it is in conformance with some specifications as the use of optical long-term storage media or with electronic track of change. PACS archives, in a hierarchical system, all digital images produced by each diagnostic imaging modality. Images and patient data can be retrieved and used for consultation or remote consultation by the reporting radiologist who requires images and reports of previous radiologic examinations or by the referring physician of the ward. Modern PACS owing to the WEB server allow remote access to extremely simplified images and data however ensuring the due regulations and access protections. Since the PACS enables a simpler data communication within the hospital, security and patient privacy should be protected. A secure and reliable PACS should be able to minimize the risk of accidental data destruction, and should prevent non authorized access to the archive with adequate security measures in relation to the acquired knowledge and based on the technological advances. Archiving of data produced by modern digital imaging is a problem now present also in small Radiology services. The technology is able to readily solve problems which were extremely complex up to some years ago as the connection between equipment and archiving system owing also to the universalization of the DICOM 3.0 standard. The evolution of communication networks and the use of standard protocols as TCP/IP can minimize problems of data and image remote transmission within the healthcare enterprise as well as over the territory. However, new problems are appearing as that of digital data security profiles and of the different systems which should ensure it. Among these, algorithms of electronic signature should be mentioned. In Italy they are validated by law and therefore can be used in digital archives in accordance with the law.

Digital image transformation and rectification of spacecraft and radar images

NASA Technical Reports Server (NTRS)

Wu, S. S. C.

1985-01-01

The application of digital processing techniques to spacecraft television pictures and radar images is discussed. The use of digital rectification to produce contour maps from spacecraft pictures is described; images with azimuth and elevation angles are converted into point-perspective frame pictures. The digital correction of the slant angle of radar images to ground scale is examined. The development of orthophoto and stereoscopic shaded relief maps from digital terrain and digital image data is analyzed. Digital image transformations and rectifications are utilized on Viking Orbiter and Lander pictures of Mars.

Digital camera with apparatus for authentication of images produced from an image file

NASA Technical Reports Server (NTRS)

Friedman, Gary L. (Inventor)

1993-01-01

A digital camera equipped with a processor for authentication of images produced from an image file taken by the digital camera is provided. The digital camera processor has embedded therein a private key unique to it, and the camera housing has a public key that is so uniquely based upon the private key that digital data encrypted with the private key by the processor may be decrypted using the public key. The digital camera processor comprises means for calculating a hash of the image file using a predetermined algorithm, and second means for encrypting the image hash with the private key, thereby producing a digital signature. The image file and the digital signature are stored in suitable recording means so they will be available together. Apparatus for authenticating at any time the image file as being free of any alteration uses the public key for decrypting the digital signature, thereby deriving a secure image hash identical to the image hash produced by the digital camera and used to produce the digital signature. The apparatus calculates from the image file an image hash using the same algorithm as before. By comparing this last image hash with the secure image hash, authenticity of the image file is determined if they match, since even one bit change in the image hash will cause the image hash to be totally different from the secure hash.

Multi-camera digital image correlation method with distributed fields of view

NASA Astrophysics Data System (ADS)

Malowany, Krzysztof; Malesa, Marcin; Kowaluk, Tomasz; Kujawinska, Malgorzata

2017-11-01

A multi-camera digital image correlation (DIC) method and system for measurements of large engineering objects with distributed, non-overlapping areas of interest are described. The data obtained with individual 3D DIC systems are stitched by an algorithm which utilizes the positions of fiducial markers determined simultaneously by Stereo-DIC units and laser tracker. The proposed calibration method enables reliable determination of transformations between local (3D DIC) and global coordinate systems. The applicability of the method was proven during in-situ measurements of a hall made of arch-shaped (18 m span) self-supporting metal-plates. The proposed method is highly recommended for 3D measurements of shape and displacements of large and complex engineering objects made from multiple directions and it provides the suitable accuracy of data for further advanced structural integrity analysis of such objects.

Advancements in remote physiological measurement and applications in human-computer interaction

NASA Astrophysics Data System (ADS)

McDuff, Daniel

2017-04-01

Physiological signals are important for tracking health and emotional states. Imaging photoplethysmography (iPPG) is a set of techniques for remotely recovering cardio-pulmonary signals from video of the human body. Advances in iPPG methods over the past decade combined with the ubiquity of digital cameras presents the possibility for many new, lowcost applications of physiological monitoring. This talk will highlight methods for recovering physiological signals, work characterizing the impact of video parameters and hardware on these measurements, and applications of this technology in human-computer interfaces.

Spectral features based tea garden extraction from digital orthophoto maps

NASA Astrophysics Data System (ADS)

Jamil, Akhtar; Bayram, Bulent; Kucuk, Turgay; Zafer Seker, Dursun

2018-05-01

The advancements in the photogrammetry and remote sensing technologies has made it possible to extract useful tangible information from data which plays a pivotal role in various application such as management and monitoring of forests and agricultural lands etc. This study aimed to evaluate the effectiveness of spectral signatures for extraction of tea gardens from 1 : 5000 scaled digital orthophoto maps obtained from Rize city in Turkey. First, the normalized difference vegetation index (NDVI) was derived from the input images to suppress the non-vegetation areas. NDVI values less than zero were discarded and the output images was normalized in the range 0-255. Individual pixels were then mapped into meaningful objects using global region growing technique. The resulting image was filtered and smoothed to reduce the impact of noise. Furthermore, geometrical constraints were applied to remove small objects (less than 500 pixels) followed by morphological opening operator to enhance the results. These objects served as building blocks for further image analysis. Finally, for the classification stage, a range of spectral values were empirically calculated for each band and applied on candidate objects to extract tea gardens. For accuracy assessment, we employed an area based similarity metric by overlapping obtained tea garden boundaries with the manually digitized tea garden boundaries created by experts of photogrammetry. The overall accuracy of the proposed method scored 89 % for tea gardens from 10 sample orthophoto maps. We concluded that exploiting the spectral signatures using object based analysis is an effective technique for extraction of dominant tree species from digital orthophoto maps.

Intelligent platforms for disease assessment: novel approaches in functional echocardiography.

PubMed

Sengupta, Partho P

2013-11-01

Accelerating trends in the dynamic digital era (from 2004 onward) has resulted in the emergence of novel parametric imaging tools that allow easy and accurate extraction of quantitative information from cardiac images. This review principally attempts to heighten the awareness of newer emerging paradigms that may advance acquisition, visualization and interpretation of the large functional data sets obtained during cardiac ultrasound imaging. Incorporation of innovative cognitive software that allow advanced pattern recognition and disease forecasting will likely transform the human-machine interface and interpretation process to achieve a more efficient and effective work environment. Novel technologies for automation and big data analytics that are already active in other fields need to be rapidly adapted to the health care environment with new academic-industry collaborations to enrich and accelerate the delivery of newer decision making tools for enhancing patient care. Copyright © 2013. Published by Elsevier Inc.

Innovative Video Diagnostic Equipment for Material Science

NASA Technical Reports Server (NTRS)

Capuano, G.; Titomanlio, D.; Soellner, W.; Seidel, A.

2012-01-01

Materials science experiments under microgravity increasingly rely on advanced optical systems to determine the physical properties of the samples under investigation. This includes video systems with high spatial and temporal resolution. The acquisition, handling, storage and transmission to ground of the resulting video data are very challenging. Since the available downlink data rate is limited, the capability to compress the video data significantly without compromising the data quality is essential. We report on the development of a Digital Video System (DVS) for EML (Electro Magnetic Levitator) which provides real-time video acquisition, high compression using advanced Wavelet algorithms, storage and transmission of a continuous flow of video with different characteristics in terms of image dimensions and frame rates. The DVS is able to operate with the latest generation of high-performance cameras acquiring high resolution video images up to 4Mpixels@60 fps or high frame rate video images up to about 1000 fps@512x512pixels.

European Union RACE program contributions to digital audiovisual communications and services

NASA Astrophysics Data System (ADS)

de Albuquerque, Augusto; van Noorden, Leon; Badique', Eric

1995-02-01

The European Union RACE (R&D in advanced communications technologies in Europe) and the future ACTS (advanced communications technologies and services) programs have been contributing and continue to contribute to world-wide developments in audio-visual services. The paper focuses on research progress in: (1) Image data compression. Several methods of image analysis leading to the use of encoders based on improved hybrid DCT-DPCM (MPEG or not), object oriented, hybrid region/waveform or knowledge-based coding methods are discussed. (2) Program production in the aspects of 3D imaging, data acquisition, virtual scene construction, pre-processing and sequence generation. (3) Interoperability and multimedia access systems. The diversity of material available and the introduction of interactive or near- interactive audio-visual services led to the development of prestandards for video-on-demand (VoD) and interworking of multimedia services storage systems and customer premises equipment.

Introducing DeBRa: a detailed breast model for radiological studies

NASA Astrophysics Data System (ADS)

Ma, Andy K. W.; Gunn, Spencer; Darambara, Dimitra G.

2009-07-01

Currently, x-ray mammography is the method of choice in breast cancer screening programmes. As the mammography technology moves from 2D imaging modalities to 3D, conventional computational phantoms do not have sufficient detail to support the studies of these advanced imaging systems. Studies of these 3D imaging systems call for a realistic and sophisticated computational model of the breast. DeBRa (Detailed Breast model for Radiological studies) is the most advanced, detailed, 3D computational model of the breast developed recently for breast imaging studies. A DeBRa phantom can be constructed to model a compressed breast, as in film/screen, digital mammography and digital breast tomosynthesis studies, or a non-compressed breast as in positron emission mammography and breast CT studies. Both the cranial-caudal and mediolateral oblique views can be modelled. The anatomical details inside the phantom include the lactiferous duct system, the Cooper ligaments and the pectoral muscle. The fibroglandular tissues are also modelled realistically. In addition, abnormalities such as microcalcifications, irregular tumours and spiculated tumours are inserted into the phantom. Existing sophisticated breast models require specialized simulation codes. Unlike its predecessors, DeBRa has elemental compositions and densities incorporated into its voxels including those of the explicitly modelled anatomical structures and the noise-like fibroglandular tissues. The voxel dimensions are specified as needed by any study and the microcalcifications are embedded into the voxels so that the microcalcification sizes are not limited by the voxel dimensions. Therefore, DeBRa works with general-purpose Monte Carlo codes. Furthermore, general-purpose Monte Carlo codes allow different types of imaging modalities and detector characteristics to be simulated with ease. DeBRa is a versatile and multipurpose model specifically designed for both x-ray and γ-ray imaging studies.

A metadata-aware application for remote scoring and exchange of tissue microarray images

PubMed Central

2013-01-01

Background The use of tissue microarrays (TMA) and advances in digital scanning microscopy has enabled the collection of thousands of tissue images. There is a need for software tools to annotate, query and share this data amongst researchers in different physical locations. Results We have developed an open source web-based application for remote scoring of TMA images, which exploits the value of Microsoft Silverlight Deep Zoom to provide a intuitive interface for zooming and panning around digital images. We use and extend existing XML-based standards to ensure that the data collected can be archived and that our system is interoperable with other standards-compliant systems. Conclusion The application has been used for multi-centre scoring of TMA slides composed of tissues from several Phase III breast cancer trials and ten different studies participating in the International Breast Cancer Association Consortium (BCAC). The system has enabled researchers to simultaneously score large collections of TMA and export the standardised data to integrate with pathological and clinical outcome data, thereby facilitating biomarker discovery. PMID:23635078

Rapid execution of fan beam image reconstruction algorithms using efficient computational techniques and special-purpose processors

NASA Astrophysics Data System (ADS)

Gilbert, B. K.; Robb, R. A.; Chu, A.; Kenue, S. K.; Lent, A. H.; Swartzlander, E. E., Jr.

1981-02-01

Rapid advances during the past ten years of several forms of computer-assisted tomography (CT) have resulted in the development of numerous algorithms to convert raw projection data into cross-sectional images. These reconstruction algorithms are either 'iterative,' in which a large matrix algebraic equation is solved by successive approximation techniques; or 'closed form'. Continuing evolution of the closed form algorithms has allowed the newest versions to produce excellent reconstructed images in most applications. This paper will review several computer software and special-purpose digital hardware implementations of closed form algorithms, either proposed during the past several years by a number of workers or actually implemented in commercial or research CT scanners. The discussion will also cover a number of recently investigated algorithmic modifications which reduce the amount of computation required to execute the reconstruction process, as well as several new special-purpose digital hardware implementations under development in laboratories at the Mayo Clinic.

Method for the visualization of landform by mapping using low altitude UAV application

NASA Astrophysics Data System (ADS)

Sharan Kumar, N.; Ashraf Mohamad Ismail, Mohd; Sukor, Nur Sabahiah Abdul; Cheang, William

2018-05-01

Unmanned Aerial Vehicle (UAV) and Digital Photogrammetry are evolving drastically in mapping technology. The significance and necessity for digital landform mapping are developing with years. In this study, a mapping workflow is applied to obtain two different input data sets which are the orthophoto and DSM. A fine flying technology is used to capture Low Altitude Aerial Photography (LAAP). Low altitude UAV (Drone) with the fixed advanced camera was utilized for imagery while computerized photogrammetry handling using Photo Scan was applied for cartographic information accumulation. The data processing through photogrammetry and orthomosaic processes is the main applications. High imagery quality is essential for the effectiveness and nature of normal mapping output such as 3D model, Digital Elevation Model (DEM), Digital Surface Model (DSM) and Ortho Images. The exactitude of Ground Control Points (GCP), flight altitude and the resolution of the camera are essential for good quality DEM and Orthophoto.

Opportunities and challenges for digital morphology

PubMed Central

2010-01-01

Advances in digital data acquisition, analysis, and storage have revolutionized the work in many biological disciplines such as genomics, molecular phylogenetics, and structural biology, but have not yet found satisfactory acceptance in morphology. Improvements in non-invasive imaging and three-dimensional visualization techniques, however, permit high-throughput analyses also of whole biological specimens, including museum material. These developments pave the way towards a digital era in morphology. Using sea urchins (Echinodermata: Echinoidea), we provide examples illustrating the power of these techniques. However, remote visualization, the creation of a specialized database, and the implementation of standardized, world-wide accepted data deposition practices prior to publication are essential to cope with the foreseeable exponential increase in digital morphological data. Reviewers This article was reviewed by Marc D. Sutton (nominated by Stephan Beck), Gonzalo Giribet (nominated by Lutz Walter), and Lennart Olsson (nominated by Purificación López-García). PMID:20604956

Digital processing of radiographic images from PACS to publishing.

PubMed

Christian, M E; Davidson, H C; Wiggins, R H; Berges, G; Cannon, G; Jackson, G; Chapman, B; Harnsberger, H R

2001-03-01

Several studies have addressed the implications of filmless radiologic imaging on telemedicine, diagnostic ability, and electronic teaching files. However, many publishers still require authors to submit hard-copy images for publication of articles and textbooks. This study compares the quality digital images directly exported from picture archive and communications systems (PACS) to images digitized from radiographic film. The authors evaluated the quality of publication-grade glossy photographs produced from digital radiographic images using 3 different methods: (1) film images digitized using a desktop scanner and then printed, (2) digital images obtained directly from PACS then printed, and (3) digital images obtained from PACS and processed to improve sharpness prior to printing. Twenty images were printed using each of the 3 different methods and rated for quality by 7 radiologists. The results were analyzed for statistically significant differences among the image sets. Subjective evaluations of the filmless images found them to be of equal or better quality than the digitized images. Direct electronic transfer of PACS images reduces the number of steps involved in creating publication-quality images as well as providing the means to produce high-quality radiographic images in a digital environment.

Digital Camera with Apparatus for Authentication of Images Produced from an Image File

NASA Technical Reports Server (NTRS)

Friedman, Gary L. (Inventor)

1996-01-01

A digital camera equipped with a processor for authentication of images produced from an image file taken by the digital camera is provided. The digital camera processor has embedded therein a private key unique to it, and the camera housing has a public key that is so uniquely related to the private key that digital data encrypted with the private key may be decrypted using the public key. The digital camera processor comprises means for calculating a hash of the image file using a predetermined algorithm, and second means for encrypting the image hash with the private key, thereby producing a digital signature. The image file and the digital signature are stored in suitable recording means so they will be available together. Apparatus for authenticating the image file as being free of any alteration uses the public key for decrypting the digital signature, thereby deriving a secure image hash identical to the image hash produced by the digital camera and used to produce the digital signature. The authenticating apparatus calculates from the image file an image hash using the same algorithm as before. By comparing this last image hash with the secure image hash, authenticity of the image file is determined if they match. Other techniques to address time-honored methods of deception, such as attaching false captions or inducing forced perspectives, are included.

21 CFR 892.2030 - Medical image digitizer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical image digitizer. 892.2030 Section 892.2030...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.2030 Medical image digitizer. (a) Identification. A medical image digitizer is a device intended to convert an analog medical image into a digital...

21 CFR 892.2030 - Medical image digitizer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Medical image digitizer. 892.2030 Section 892.2030...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.2030 Medical image digitizer. (a) Identification. A medical image digitizer is a device intended to convert an analog medical image into a digital...

21 CFR 892.2030 - Medical image digitizer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Medical image digitizer. 892.2030 Section 892.2030...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.2030 Medical image digitizer. (a) Identification. A medical image digitizer is a device intended to convert an analog medical image into a digital...

21 CFR 892.2030 - Medical image digitizer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Medical image digitizer. 892.2030 Section 892.2030...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.2030 Medical image digitizer. (a) Identification. A medical image digitizer is a device intended to convert an analog medical image into a digital...

Bio-image warehouse system: concept and implementation of a diagnosis-based data warehouse for advanced imaging modalities in neuroradiology.

PubMed

Minati, L; Ghielmetti, F; Ciobanu, V; D'Incerti, L; Maccagnano, C; Bizzi, A; Bruzzone, M G

2007-03-01

Advanced neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), chemical shift spectroscopy imaging (CSI), diffusion tensor imaging (DTI), and perfusion-weighted imaging (PWI) create novel challenges in terms of data storage and management: huge amounts of raw data are generated, the results of analysis may depend on the software and settings that have been used, and most often intermediate files are inherently not compliant with the current DICOM (digital imaging and communication in medicine) standard, as they contain multidimensional complex and tensor arrays and various other types of data structures. A software architecture, referred to as Bio-Image Warehouse System (BIWS), which can be used alongside a radiology information system/picture archiving and communication system (RIS/PACS) system to store neuroimaging data for research purposes, is presented. The system architecture is conceived with the purpose of enabling to query by diagnosis according to a predefined two-layered classification taxonomy. The operational impact of the system and the time needed to get acquainted with the web-based interface and with the taxonomy are found to be limited. The development of modules enabling automated creation of statistical templates is proposed.

An Evaluation of ALOS Data in Disaster Applications

NASA Astrophysics Data System (ADS)

Igarashi, Tamotsu; Igarashi, Tamotsu; Furuta, Ryoich; Ono, Makoto

ALOS is the advanced land observing satellite, providing image data from onboard sensors; PRISM, AVNIR-2 and PALSAR. PRISM is the sensor of panchromatic stereo, high resolution three-line-scanner to characterize the earth surface. The accuracy of position in image and height of Digital Surface Model (DSM) are high, therefore the geographic information extraction is improved in the field of disaster applications with providing images of disaster area. Especially pan-sharpened 3D image composed with PRISM and the four-band visible near-infrared radiometer AVNIR-2 data is expected to provide information to understand the geographic and topographic feature. PALSAR is the advanced multi-functional synthetic aperture radar (SAR) operated in L-band, appropriate for the use of land surface feature characterization. PALSAR has many improvements from JERS-1/SAR, such as high sensitivity, having high resolution, polarimetric and scan SAR observation modes. PALSAR is also applicable for SAR interferometry processing. This paper describes the evaluation of ALOS data characteristic from the view point of disaster applications, through some exercise applications.

Exploitation of commercial remote sensing images: reality ignored?

NASA Astrophysics Data System (ADS)

Allen, Paul C.

1999-12-01

The remote sensing market is on the verge of being awash in commercial high-resolution images. Market estimates are based on the growing numbers of planned commercial remote sensing electro-optical, radar, and hyperspectral satellites and aircraft. EarthWatch, Space Imaging, SPOT, and RDL among others are all working towards launch and service of one to five meter panchromatic or radar-imaging satellites. Additionally, new advances in digital air surveillance and reconnaissance systems, both manned and unmanned, are also expected to expand the geospatial customer base. Regardless of platform, image type, or location, each system promises images with some combination of increased resolution, greater spectral coverage, reduced turn-around time (request-to- delivery), and/or reduced image cost. For the most part, however, market estimates for these new sources focus on the raw digital images (from collection to the ground station) while ignoring the requirements for a processing and exploitation infrastructure comprised of exploitation tools, exploitation training, library systems, and image management systems. From this it would appear the commercial imaging community has failed to learn the hard lessons of national government experience choosing instead to ignore reality and replicate the bias of collection over processing and exploitation. While this trend may be not impact the small quantity users that exist today it will certainly adversely affect the mid- to large-sized users of the future.

3-D movies using microprocessor-controlled optoelectronic spectacles

NASA Astrophysics Data System (ADS)

Jacobs, Ken; Karpf, Ron

2012-02-01

Despite rapid advances in technology, 3-D movies are impractical for general movie viewing. A new approach that opens all content for casual 3-D viewing is needed. 3Deeps--advanced microprocessor controlled optoelectronic spectacles--provides such a new approach to 3-D. 3Deeps works on a different principle than other methods for 3-D. 3-D movies typically use the asymmetry of dual images to produce stereopsis, necessitating costly dual-image content, complex formatting and transmission standards, and viewing via a corresponding selection device. In contrast, all 3Deeps requires to view movies in realistic depth is an illumination asymmetry--a controlled difference in optical density between the lenses. When a 2-D movie has been projected for viewing, 3Deeps converts every scene containing lateral motion into realistic 3-D. Put on 3Deeps spectacles for 3-D viewing, or remove them for viewing in 2-D. 3Deeps works for all analogue and digital 2-D content, by any mode of transmission, and for projection screens, digital or analogue monitors. An example using aerial photography is presented. A movie consisting of successive monoscopic aerial photographs appears in realistic 3-D when viewed through 3Deeps spectacles.

Neural networks: Application to medical imaging

NASA Technical Reports Server (NTRS)

Clarke, Laurence P.

1994-01-01

The research mission is the development of computer assisted diagnostic (CAD) methods for improved diagnosis of medical images including digital x-ray sensors and tomographic imaging modalities. The CAD algorithms include advanced methods for adaptive nonlinear filters for image noise suppression, hybrid wavelet methods for feature segmentation and enhancement, and high convergence neural networks for feature detection and VLSI implementation of neural networks for real time analysis. Other missions include (1) implementation of CAD methods on hospital based picture archiving computer systems (PACS) and information networks for central and remote diagnosis and (2) collaboration with defense and medical industry, NASA, and federal laboratories in the area of dual use technology conversion from defense or aerospace to medicine.

Faithful reconstruction of digital holograms captured by FINCH using a Hamming window function in the Fresnel propagation.

PubMed

Siegel, Nisan; Rosen, Joseph; Brooker, Gary

2013-10-01

Recent advances in Fresnel incoherent correlation holography (FINCH) increase the signal-to-noise ratio in hologram recording by interference of images from two diffractive lenses with focal lengths close to the image plane. Holograms requiring short reconstruction distances are created that reconstruct poorly with existing Fresnel propagation methods. Here we show a dramatic improvement in reconstructed fluorescent images when a 2D Hamming window function substituted for the disk window typically used to bound the impulse response in the Fresnel propagation. Greatly improved image contrast and quality are shown for simulated and experimentally determined FINCH holograms using a 2D Hamming window without significant loss in lateral or axial resolution.

Rhinoceros Feet Step Out of a Rule-of-Thumb: A Wildlife Imaging Pioneering Approach of Synchronized Computed Tomography-Digital Radiography

PubMed Central

Saragusty, Joseph; Göritz, Frank; Potier, Romain; Mulot, Baptiste; Maillot, Alexis; Etienne, Pascal; Bernardino, Rui; Fernandes, Teresa; Mews, Jurgen; Hildebrandt, Thomas Bernd

2014-01-01

Currently, radiography is the only imaging technique used to diagnose bone pathology in wild animals situated under “field conditions”. Nevertheless, while chronic foot disease in captive mega-herbivores is widely reported, foot radiographic imaging is confronted with scarcity of studies. Numerous hindrances lead to such limited numbers and it became very clear that the traditional perspective on bone imaging in domestic animals based on extensive studies and elaborated statistical evaluations cannot be extrapolated to their non-domestic relatives. For these reasons, the authors initiated a multi-modality imaging study and established a pioneering approach of synchronized computed tomography (CT) and digital radiography (DR), based on X-ray projections derived from three-dimensional CT reconstructed images. Whereas this approach can be applied in any clinical field, as a case of outstanding importance and great concern for zoological institutions, we selected foot bone pathologies in captive rhinoceroses to demonstrate the manifold applications of the method. Several advances were achieved, endowing the wildlife clinician with all-important tools: prototype DR exposure protocols and a modus operandi for foot positioning, advancing both traditional projections and, for the first-time, species-related radiographic views; assessment of radiographic diagnostic value for the whole foot and, in premiere, for each autopodial bone; together with additional insights into radiographic appearance of bone anatomy and pathology with a unique, simultaneous CT-DR correlation. Based on its main advantages in availing a wide range of keystone data in wildlife imaging from a limited number of examined subjects and combining advantages of CT as the golden standard method for bone diseases' diagnostic with DR's clinical feasibility under field conditions, synchronized CT-DR presents a new perspective on wildlife's health management. With this we hope to provide veterinary clinicians with concrete imaging techniques and substantial diagnostic tools, which facilitate straightforward attainment and interpretation of field radiography images taken worldwide. PMID:24963807

Rhinoceros feet step out of a rule-of-thumb: a wildlife imaging pioneering approach of synchronized computed tomography-digital radiography.

PubMed

Galateanu, Gabriela; Hermes, Robert; Saragusty, Joseph; Göritz, Frank; Potier, Romain; Mulot, Baptiste; Maillot, Alexis; Etienne, Pascal; Bernardino, Rui; Fernandes, Teresa; Mews, Jurgen; Hildebrandt, Thomas Bernd

2014-01-01

Currently, radiography is the only imaging technique used to diagnose bone pathology in wild animals situated under "field conditions". Nevertheless, while chronic foot disease in captive mega-herbivores is widely reported, foot radiographic imaging is confronted with scarcity of studies. Numerous hindrances lead to such limited numbers and it became very clear that the traditional perspective on bone imaging in domestic animals based on extensive studies and elaborated statistical evaluations cannot be extrapolated to their non-domestic relatives. For these reasons, the authors initiated a multi-modality imaging study and established a pioneering approach of synchronized computed tomography (CT) and digital radiography (DR), based on X-ray projections derived from three-dimensional CT reconstructed images. Whereas this approach can be applied in any clinical field, as a case of outstanding importance and great concern for zoological institutions, we selected foot bone pathologies in captive rhinoceroses to demonstrate the manifold applications of the method. Several advances were achieved, endowing the wildlife clinician with all-important tools: prototype DR exposure protocols and a modus operandi for foot positioning, advancing both traditional projections and, for the first-time, species-related radiographic views; assessment of radiographic diagnostic value for the whole foot and, in premiere, for each autopodial bone; together with additional insights into radiographic appearance of bone anatomy and pathology with a unique, simultaneous CT-DR correlation. Based on its main advantages in availing a wide range of keystone data in wildlife imaging from a limited number of examined subjects and combining advantages of CT as the golden standard method for bone diseases' diagnostic with DR's clinical feasibility under field conditions, synchronized CT-DR presents a new perspective on wildlife's health management. With this we hope to provide veterinary clinicians with concrete imaging techniques and substantial diagnostic tools, which facilitate straightforward attainment and interpretation of field radiography images taken worldwide.

Barriers and facilitators to adoption of soft copy interpretation from the user perspective: Lessons learned from filmless radiology for slideless pathology

PubMed Central

Patterson, Emily S.; Rayo, Mike; Gill, Carolina; Gurcan, Metin N.

2011-01-01

Background: Adoption of digital images for pathological specimens has been slower than adoption of digital images in radiology, despite a number of anticipated advantages for digital images in pathology. In this paper, we explore the factors that might explain this slower rate of adoption. Materials and Method: Semi-structured interviews on barriers and facilitators to the adoption of digital images were conducted with two radiologists, three pathologists, and one pathologist's assistant. Results: Barriers and facilitators to adoption of digital images were reported in the areas of performance, workflow-efficiency, infrastructure, integration with other software, and exposure to digital images. The primary difference between the settings was that performance with the use of digital images as compared to the traditional method was perceived to be higher in radiology and lower in pathology. Additionally, exposure to digital images was higher in radiology than pathology, with some radiologists exclusively having been trained and/or practicing with digital images. The integration of digital images both improved and reduced efficiency in routine and non-routine workflow patterns in both settings, and was variable across the different organizations. A comparison of these findings with prior research on adoption of other health information technologies suggests that the barriers to adoption of digital images in pathology are relatively tractable. Conclusions: Improving performance using digital images in pathology would likely accelerate adoption of innovative technologies that are facilitated by the use of digital images, such as electronic imaging databases, electronic health records, double reading for challenging cases, and computer-aided diagnostic systems. PMID:21383925

Image manipulation: Fraudulence in digital dental records: Study and review

PubMed Central

Chowdhry, Aman; Sircar, Keya; Popli, Deepika Bablani; Tandon, Ankita

2014-01-01

Introduction: In present-day times, freely available software allows dentists to tweak their digital records as never before. But, there is a fine line between acceptable enhancements and scientific delinquency. Aims and Objective: To manipulate digital images (used in forensic dentistry) of casts, lip prints, and bite marks in order to highlight tampering techniques and methods of detecting and preventing manipulation of digital images. Materials and Methods: Digital image records of forensic data (casts, lip prints, and bite marks photographed using Samsung Techwin L77 digital camera) were manipulated using freely available software. Results: Fake digital images can be created either by merging two or more digital images, or by altering an existing image. Discussion and Conclusion: Retouched digital images can be used for fraudulent purposes in forensic investigations. However, tools are available to detect such digital frauds, which are extremely difficult to assess visually. Thus, all digital content should mandatorily have attached metadata and preferably watermarking in order to avert their malicious re-use. Also, computer alertness, especially about imaging software's, should be promoted among forensic odontologists/dental professionals. PMID:24696587

Digital image transformation and rectification of spacecraft and radar images

USGS Publications Warehouse

Wu, S.S.C.

1985-01-01

Digital image transformation and rectification can be described in three categories: (1) digital rectification of spacecraft pictures on workable stereoplotters; (2) digital correction of radar image geometry; and (3) digital reconstruction of shaded relief maps and perspective views including stereograms. Digital rectification can make high-oblique pictures workable on stereoplotters that would otherwise not accommodate such extreme tilt angles. It also enables panoramic line-scan geometry to be used to compile contour maps with photogrammetric plotters. Rectifications were digitally processed on both Viking Orbiter and Lander pictures of Mars as well as radar images taken by various radar systems. By merging digital terrain data with image data, perspective and three-dimensional views of Olympus Mons and Tithonium Chasma, also of Mars, are reconstructed through digital image processing. ?? 1985.

High-speed particle tracking in microscopy using SPAD image sensors

NASA Astrophysics Data System (ADS)

Gyongy, Istvan; Davies, Amy; Miguelez Crespo, Allende; Green, Andrew; Dutton, Neale A. W.; Duncan, Rory R.; Rickman, Colin; Henderson, Robert K.; Dalgarno, Paul A.

2018-02-01

Single photon avalanche diodes (SPADs) are used in a wide range of applications, from fluorescence lifetime imaging microscopy (FLIM) to time-of-flight (ToF) 3D imaging. SPAD arrays are becoming increasingly established, combining the unique properties of SPADs with widefield camera configurations. Traditionally, the photosensitive area (fill factor) of SPAD arrays has been limited by the in-pixel digital electronics. However, recent designs have demonstrated that by replacing the complex digital pixel logic with simple binary pixels and external frame summation, the fill factor can be increased considerably. A significant advantage of such binary SPAD arrays is the high frame rates offered by the sensors (>100kFPS), which opens up new possibilities for capturing ultra-fast temporal dynamics in, for example, life science cellular imaging. In this work we consider the use of novel binary SPAD arrays in high-speed particle tracking in microscopy. We demonstrate the tracking of fluorescent microspheres undergoing Brownian motion, and in intra-cellular vesicle dynamics, at high frame rates. We thereby show how binary SPAD arrays can offer an important advance in live cell imaging in such fields as intercellular communication, cell trafficking and cell signaling.

Toward virtual anatomy: a stereoscopic 3-D interactive multimedia computer program for cranial osteology.

PubMed

Trelease, R B

1996-01-01

Advances in computer visualization and user interface technologies have enabled development of "virtual reality" programs that allow users to perceive and to interact with objects in artificial three-dimensional environments. Such technologies were used to create an image database and program for studying the human skull, a specimen that has become increasingly expensive and scarce. Stereoscopic image pairs of a museum-quality skull were digitized from multiple views. For each view, the stereo pairs were interlaced into a single, field-sequential stereoscopic picture using an image processing program. The resulting interlaced image files are organized in an interactive multimedia program. At run-time, gray-scale 3-D images are displayed on a large-screen computer monitor and observed through liquid-crystal shutter goggles. Users can then control the program and change views with a mouse and cursor to point-and-click on screen-level control words ("buttons"). For each view of the skull, an ID control button can be used to overlay pointers and captions for important structures. Pointing and clicking on "hidden buttons" overlying certain structures triggers digitized audio spoken word descriptions or mini lectures.

Techniques for digital enhancement of Landsat MSS data using an Apple II+ microcomputer

NASA Technical Reports Server (NTRS)

Harrington, J. A., Jr.; Cartin, K. F.

1984-01-01

The information provided by remotely sensed data collected from orbiting platforms has been useful in many research fields. Particularly convenient for evaluation are generally digital data stored on computer compatible tapes (CCT's). The major advantages of CCT's are the quality of the data and the accessibility to computer manipulation. Minicomputer systems are widely used for the required computer processing operations. However, microprocessor-related technological advances make it now possible to process CCT data with computing systems which can be obtained at a much lower price than minicomputer systems. A detailed description is provided of the design considerations of a microcomputer-based Digital Image Analysis System (DIAS). Particular attention is given to the algorithms which are incorporated for eighter edge enhancement or smoothing Landsat multispectral scanner data.

Digital radiographic imaging: is the dental practice ready?

PubMed

Parks, Edwin T

2008-04-01

Digital radiographic imaging is slowly, but surely, replacing film-based imaging. It has many advantages over traditional imaging, but the technology also has some drawbacks. The author presents an overview of the types of digital image receptors available, image enhancement software and the range of costs for the new technology. PRACTICE IMPLICATIONS. The expenses associated with converting to digital radiographic imaging are considerable. The purpose of this article is to provide the clinician with an overview of digital radiographic imaging technology so that he or she can be an informed consumer when evaluating the numerous digital systems in the marketplace.

NASA planetary data: applying planetary satellite remote sensing data in the classroom

NASA Technical Reports Server (NTRS)

Liggett, P.; Dobinson, E.; Sword, B.; Hughes, D.; Martin, M.; Martin, D.

2002-01-01

NASA supports several data archiving and distribution mechanisms that provide a means whereby scientists can participate in education and outreach through the use of technology for data and information dissemination. The Planetary Data System (PDS) is sponsored by NASA's Office of Space Science. Its purpose is to ensure the long-term usability of NASA data and to stimulate advanced research. In addition, the NASA Regional Planetary Image Facility (RPIF), an international system of planetary image libraries, maintains photographic and digital data as well as mission documentation and cartographic data.

Creep Measurement Video Extensometer

NASA Technical Reports Server (NTRS)

Jaster, Mark; Vickerman, Mary; Padula, Santo, II; Juhas, John

2011-01-01

Understanding material behavior under load is critical to the efficient and accurate design of advanced aircraft and spacecraft. Technologies such as the one disclosed here allow accurate creep measurements to be taken automatically, reducing error. The goal was to develop a non-contact, automated system capable of capturing images that could subsequently be processed to obtain the strain characteristics of these materials during deformation, while maintaining adequate resolution to capture the true deformation response of the material. The measurement system comprises a high-resolution digital camera, computer, and software that work collectively to interpret the image.

Preoperative Planning in Orthopaedic Surgery. Current Practice and Evolving Applications.

PubMed

Atesok, Kivanc; Galos, David; Jazrawi, Laith M; Egol, Kenneth A

2015-12-01

Preoperative planning is an essential prerequisite for the success of orthopaedic procedures. Traditionally, the exercise has involved the written down, step by step "blueprint" of the surgical procedure. Preoperative planning of the technical aspects of the orthopaedic procedure has been performed on hardcopy radiographs using various methods such as copying the radiographic image on tracing papers to practice the planned interventions. This method has become less practical due to variability in radiographic magnification and increasing implementation of digital imaging systems. Advances in technology along with recognition of the importance of surgical safety protocols resulted in widespread changes in orthopaedic preoperative planning approaches. Nowadays, perioperative "briefings" have gained particular importance and novel planning methods have started to integrate into orthopaedic practice. These methods include using software that enables surgeons to perform preoperative planning on digital radiographs and to construct 3D digital models or prototypes of various orthopaedic pathologies from a patient's CT scans to practice preoperatively. Evidence-to-date suggests that preoperative planning and briefings are effective means of favorably influencing the outcomes of orthopaedic procedures.

Pitfalls in colour photography of choroidal tumours

PubMed Central

Schalenbourg, A; Zografos, L

2013-01-01

Colour imaging of fundus tumours has been transformed by the development of digital and confocal scanning laser photography. These advances provide numerous benefits, such as panoramic images, increased contrast, non-contact wide-angle imaging, non-mydriatic photography, and simultaneous angiography. False tumour colour representation can, however, cause serious diagnostic errors. Large choroidal tumours can be totally invisible on angiography. Pseudogrowth can occur because of artefacts caused by different methods of fundus illumination, movement of reference blood vessels, and flattening of Bruch's membrane and sclera when tumour regression occurs. Awareness of these pitfalls should prevent the clinician from misdiagnosing tumours and wrongfully concluding that a tumour has grown. PMID:23238442

Pitfalls in colour photography of choroidal tumours.

PubMed

Schalenbourg, A; Zografos, L

2013-02-01

Colour imaging of fundus tumours has been transformed by the development of digital and confocal scanning laser photography. These advances provide numerous benefits, such as panoramic images, increased contrast, non-contact wide-angle imaging, non-mydriatic photography, and simultaneous angiography. False tumour colour representation can, however, cause serious diagnostic errors. Large choroidal tumours can be totally invisible on angiography. Pseudogrowth can occur because of artefacts caused by different methods of fundus illumination, movement of reference blood vessels, and flattening of Bruch's membrane and sclera when tumour regression occurs. Awareness of these pitfalls should prevent the clinician from misdiagnosing tumours and wrongfully concluding that a tumour has grown.

Document Examination: Applications of Image Processing Systems.

PubMed

Kopainsky, B

1989-12-01

Dealing with images is a familiar business for an expert in questioned documents: microscopic, photographic, infrared, and other optical techniques generate images containing the information he or she is looking for. A recent method for extracting most of this information is digital image processing, ranging from the simple contrast and contour enhancement to the advanced restoration of blurred texts. When combined with a sophisticated physical imaging system, an image pricessing system has proven to be a powerful and fast tool for routine non-destructive scanning of suspect documents. This article reviews frequent applications, comprising techniques to increase legibility, two-dimensional spectroscopy (ink discrimination, alterations, erased entries, etc.), comparison techniques (stamps, typescript letters, photo substitution), and densitometry. Computerized comparison of handwriting is not included. Copyright © 1989 Central Police University.

49 CFR 384.227 - Record of digital image or photograph.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 5 2014-10-01 2014-10-01 false Record of digital image or photograph. 384.227... § 384.227 Record of digital image or photograph. The State must: (a) Record the digital color image or.... The digital color image or photograph or black and white laser engraved photograph must either be made...

49 CFR 384.227 - Record of digital image or photograph.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 5 2013-10-01 2013-10-01 false Record of digital image or photograph. 384.227... § 384.227 Record of digital image or photograph. The State must: (a) Record the digital color image or.... The digital color image or photograph or black and white laser engraved photograph must either be made...

49 CFR 384.227 - Record of digital image or photograph.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Record of digital image or photograph. 384.227... § 384.227 Record of digital image or photograph. The State must: (a) Record the digital color image or.... The digital color image or photograph or black and white laser engraved photograph must either be made...

49 CFR 384.227 - Record of digital image or photograph.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 5 2012-10-01 2012-10-01 false Record of digital image or photograph. 384.227... § 384.227 Record of digital image or photograph. The State must: (a) Record the digital color image or.... The digital color image or photograph or black and white laser engraved photograph must either be made...

How to optimize radiological images captured from digital cameras, using the Adobe Photoshop 6.0 program.

PubMed

Chalazonitis, A N; Koumarianos, D; Tzovara, J; Chronopoulos, P

2003-06-01

Over the past decade, the technology that permits images to be digitized and the reduction in the cost of digital equipment allows quick digital transfer of any conventional radiological film. Images then can be transferred to a personal computer, and several software programs are available that can manipulate their digital appearance. In this article, the fundamentals of digital imaging are discussed, as well as the wide variety of optional adjustments that the Adobe Photoshop 6.0 (Adobe Systems, San Jose, CA) program can offer to present radiological images with satisfactory digital imaging quality.

Impressive Performance: New Disposable Digital Ureteroscope Allows for Extreme Lower Pole Access and Use of 365 μm Holmium Laser Fiber.

PubMed

Leveillee, Raymond J; Kelly, Emily Fell

2016-01-01

Since the development of the first flexible ureteroscope, in 1964, technological advances in image quality, flexibility, and deflection have led to the development of the first single-use digital flexible ureteroscope, LithoVue™ (Boston Scientific, Marlborough, MA). With respect to reusable fiber-optic and now digital ureteroscopes, there is an initial capital cost of several thousand dollars (USD) as well as, controversy regarding durability, the cost of repairs and the burdensome reprocessing steps of ureteroscopy. The single-use LithoVue eliminates the need for costly repairs, the occurrence of unpredictable performance, and procedural delays. Renal stones located in the lower pole of the kidney can be extremely challenging as extreme deflections of greater than 160° are difficult to maintain and are often further compromised when using stone treatment tools, such as laser fibers and baskets. This case describes an initial use of the LithoVue digital disposable ureteroscope in the effective treatment of lower pole calculi using a 365 μm holmium laser fiber. A 35-year-old female, with a medical history significant for chronic bacteriuria, and recurrent symptomatic culture proven urinary tract infections, underwent localization studies. Retrograde ureteropyelography demonstrated two calcifications adjoining, measuring a total of 1.4 cm, overlying the left renal shadow. Urine aspirated yielded clinically significant, >100,000, Escherichia coli and Streptococcus anginosus bacteriuria, which was felt to be originating from the left lower calix. This case used the newly FDA-approved LithoVue flexible disposable ureteroscope. The two stones were seen using the ureteroscope passed through an ureteral access sheath in the lower pole calix. A 365 μm holmium laser fiber was inserted into the ureteroscope and advanced toward the stones. There was no loss of deflection as the ureteroscope performed reproducibly. The laser was used for more than 4000 pulses at 15 W, producing mucoid debris and fragments. A 1.9F nitinol basket was, then, used to extract the fragments, and the patient was rendered stone free. Treatment success was confirmed by plain abdominal film obtained 1 week after stent removal. The LithoVue system single-use digital flexible ureteroscope provides an economical advantage over both reusable digital and fiber-optic ureteroscopes. The LithoVue system uses the enhanced image resolution of the digital complementary metal oxide semiconductor imager, similar to other reusable digital ureteroscopes, while maintaining the small ureteroscope size of a flexible fiber-optic ureteroscope, allowing for consistent and effective lower pole access. Deflection characteristics are maintained even when thicker laser fibers are passed through the working channel.

Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution

PubMed Central

Ding, Yichen; Lee, Juhyun; Ma, Jianguo; Sung, Kevin; Yokota, Tomohiro; Singh, Neha; Dooraghi, Mojdeh; Abiri, Parinaz; Wang, Yibin; Kulkarni, Rajan P.; Nakano, Atsushi; Nguyen, Thao P.; Fei, Peng; Hsiai, Tzung K.

2017-01-01

Light-sheet fluorescence microscopy (LSFM) serves to advance developmental research and regenerative medicine. Coupled with the paralleled advances in fluorescence-friendly tissue clearing technique, our cardiac LSFM enables dual-sided illumination to rapidly uncover the architecture of murine hearts over 10 by 10 by 10 mm3 in volume; thereby allowing for localizing progenitor differentiation to the cardiomyocyte lineage and AAV9-mediated expression of exogenous transmembrane potassium channels with high contrast and resolution. Without the steps of stitching image columns, pivoting the light-sheet and sectioning the heart mechanically, we establish a holistic strategy for 3-dimentional reconstruction of the “digital murine heart” to assess aberrant cardiac structures as well as the spatial distribution of the cardiac lineages in neonates and ion-channels in adults. PMID:28165052

The AAPM/RSNA physics tutorial for residents: digital fluoroscopy.

PubMed

Pooley, R A; McKinney, J M; Miller, D A

2001-01-01

A digital fluoroscopy system is most commonly configured as a conventional fluoroscopy system (tube, table, image intensifier, video system) in which the analog video signal is converted to and stored as digital data. Other methods of acquiring the digital data (eg, digital or charge-coupled device video and flat-panel detectors) will become more prevalent in the future. Fundamental concepts related to digital imaging in general include binary numbers, pixels, and gray levels. Digital image data allow the convenient use of several image processing techniques including last image hold, gray-scale processing, temporal frame averaging, and edge enhancement. Real-time subtraction of digital fluoroscopic images after injection of contrast material has led to widespread use of digital subtraction angiography (DSA). Additional image processing techniques used with DSA include road mapping, image fade, mask pixel shift, frame summation, and vessel size measurement. Peripheral angiography performed with an automatic moving table allows imaging of the peripheral vasculature with a single contrast material injection.

Detecting Copy Move Forgery In Digital Images

NASA Astrophysics Data System (ADS)

Gupta, Ashima; Saxena, Nisheeth; Vasistha, S. K.

2012-03-01

In today's world several image manipulation software's are available. Manipulation of digital images has become a serious problem nowadays. There are many areas like medical imaging, digital forensics, journalism, scientific publications, etc, where image forgery can be done very easily. To determine whether a digital image is original or doctored is a big challenge. To find the marks of tampering in a digital image is a challenging task. The detection methods can be very useful in image forensics which can be used as a proof for the authenticity of a digital image. In this paper we propose the method to detect region duplication forgery by dividing the image into overlapping block and then perform searching to find out the duplicated region in the image.

Film cameras or digital sensors? The challenge ahead for aerial imaging

USGS Publications Warehouse

Light, D.L.

1996-01-01

Cartographic aerial cameras continue to play the key role in producing quality products for the aerial photography business, and specifically for the National Aerial Photography Program (NAPP). One NAPP photograph taken with cameras capable of 39 lp/mm system resolution can contain the equivalent of 432 million pixels at 11 ??m spot size, and the cost is less than $75 per photograph to scan and output the pixels on a magnetic storage medium. On the digital side, solid state charge coupled device linear and area arrays can yield quality resolution (7 to 12 ??m detector size) and a broader dynamic range. If linear arrays are to compete with film cameras, they will require precise attitude and positioning of the aircraft so that the lines of pixels can be unscrambled and put into a suitable homogeneous scene that is acceptable to an interpreter. Area arrays need to be much larger than currently available to image scenes competitive in size with film cameras. Analysis of the relative advantages and disadvantages of the two systems show that the analog approach is more economical at present. However, as arrays become larger, attitude sensors become more refined, global positioning system coordinate readouts become commonplace, and storage capacity becomes more affordable, the digital camera may emerge as the imaging system for the future. Several technical challenges must be overcome if digital sensors are to advance to where they can support mapping, charting, and geographic information system applications.

Multiscale image processing and antiscatter grids in digital radiography.

PubMed

Lo, Winnie Y; Hornof, William J; Zwingenberger, Allison L; Robertson, Ian D

2009-01-01

Scatter radiation is a source of noise and results in decreased signal-to-noise ratio and thus decreased image quality in digital radiography. We determined subjectively whether a digitally processed image made without a grid would be of similar quality to an image made with a grid but without image processing. Additionally the effects of exposure dose and of a using a grid with digital radiography on overall image quality were studied. Thoracic and abdominal radiographs of five dogs of various sizes were made. Four acquisition techniques were included (1) with a grid, standard exposure dose, digital image processing; (2) without a grid, standard exposure dose, digital image processing; (3) without a grid, half the exposure dose, digital image processing; and (4) with a grid, standard exposure dose, no digital image processing (to mimic a film-screen radiograph). Full-size radiographs as well as magnified images of specific anatomic regions were generated. Nine reviewers rated the overall image quality subjectively using a five-point scale. All digitally processed radiographs had higher overall scores than nondigitally processed radiographs regardless of patient size, exposure dose, or use of a grid. The images made at half the exposure dose had a slightly lower quality than those made at full dose, but this was only statistically significant in magnified images. Using a grid with digital image processing led to a slight but statistically significant increase in overall quality when compared with digitally processed images made without a grid but whether this increase in quality is clinically significant is unknown.

Digital Breast Tomosynthesis: State of the Art

PubMed Central

Vedantham, Srinivasan; Vijayaraghavan, Gopal R.; Kopans, Daniel B.

2015-01-01

This topical review on digital breast tomosynthesis (DBT) is provided with the intent of describing the state of the art in terms of technology, results from recent clinical studies, advanced applications, and ongoing efforts to develop multimodality imaging systems that include DBT. Particular emphasis is placed on clinical studies. The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening. Retrospective multireader multicase studies show either noninferiority or superiority of DBT compared with mammography. Methods to curtail radiation dose are of importance. © RSNA, 2015 PMID:26599926

Highlighting the medical applications of 3D printing in Egypt

PubMed Central

Abdelghany, Khaled; Hamza, Hosamuddin

2015-01-01

Computer-assisted designing/computer-assisted manufacturing (CAD/CAM) technology has enabled medical practitioners to tailor physical models in a patient and purpose-specific fashion. It allows the designing and manufacturing of templates, appliances and devices with a high range of accuracy using biocompatible materials. The technique, nevertheless, relies on digital scanning (e.g., using intraoral scanners) and/or digital imaging (e.g., CT and MRI). In developing countries, there are some technical and financial limitations of implementing such advanced tools as an essential portion of medical applications. This paper focuses on the surgical and dental use of 3D printing technology in Egypt as a developing country. PMID:26807414

Unified Digital Image Display And Processing System

NASA Astrophysics Data System (ADS)

Horii, Steven C.; Maguire, Gerald Q.; Noz, Marilyn E.; Schimpf, James H.

1981-11-01

Our institution like many others, is faced with a proliferation of medical imaging techniques. Many of these methods give rise to digital images (e.g. digital radiography, computerized tomography (CT) , nuclear medicine and ultrasound). We feel that a unified, digital system approach to image management (storage, transmission and retrieval), image processing and image display will help in integrating these new modalities into the present diagnostic radiology operations. Future techniques are likely to employ digital images, so such a system could readily be expanded to include other image sources. We presently have the core of such a system. We can both view and process digital nuclear medicine (conventional gamma camera) images, positron emission tomography (PET) and CT images on a single system. Images from our recently installed digital radiographic unit can be added. Our paper describes our present system, explains the rationale for its configuration, and describes the directions in which it will expand.

Determining Angle of Humeral Torsion Using Image Software Technique.

PubMed

Patil, Sachin; Sethi, Madhu; Vasudeva, Neelam

2016-10-01

Several researches have been done on the measurement of angles of humeral torsion in different parts of the world. Previously described methods were more complicated, not much accurate, cumbersome or required sophisticated instruments. The present study was conducted with the aim to determine the angles of humeral torsion with a newer simple technique using digital images and image tool software. A total of 250 dry normal adult human humeri were obtained from the bone bank of Department of Anatomy. The length and mid-shaft circumference of each bone was measured with the help of measuring tape. The angle of humeral torsion was measured directly from the digital images by the image analysis using Image Tool 3.0 software program. The data was analysed statistically with SPSS version 17 using unpaired t-test and Spearman's rank order correlation coefficient. The mean angle of torsion was 64.57°±7.56°. On the right side it was 66.84°±9.69°, whereas, on the left side it was found to be 63.31±9.50°. The mean humeral length was 31.6 cm on right side and 30.33 cm on left side. Mid shaft circumference was 5.79 on right side and 5.63 cm on left side. No statistical differences were seen in angles between right and left humeri (p>0.001). From our study, it was concluded that circumference of shaft is inversely proportional to angle of humeral torsion. The length and side of humerus has no relation with the humeral torsion. With advancement of digital technology, it is better to use new image softwares for anatomical studies.

Advances in upper extremity prosthetics.

PubMed

Zlotolow, Dan A; Kozin, Scott H

2012-11-01

Until recently, upper extremity prostheses had changed little since World War II. In 2006, the Defense Advanced Research Projects Agency responded to an increasing number of military amputees with the Revolutionizing Prosthetics program. The program has yielded several breakthroughs both in the engineering of new prosthetic arms and in the control of those arms. Direct brain-wave control of a limb with 22° of freedom may be within reach. In the meantime, advances such as individually powered digits have opened the door to multifunctional full and partial hand prostheses. Restoring sensation to the prosthetic limb remains a major challenge to full integration of the limb into a patient's self-image. Copyright © 2012 Elsevier Inc. All rights reserved.

A portfolio of products from the rapid terrain visualization interferometric SAR

NASA Astrophysics Data System (ADS)

Bickel, Douglas L.; Doerry, Armin W.

2007-04-01

The Rapid Terrain Visualization interferometric synthetic aperture radar was designed and built at Sandia National Laboratories as part of an Advanced Concept Technology Demonstration (ACTD) to "demonstrate the technologies and infrastructure to meet the Army requirement for rapid generation of digital topographic data to support emerging crisis or contingencies." This sensor was built by Sandia National Laboratories for the Joint Programs Sustainment and Development (JPSD) Project Office to provide highly accurate digital elevation models (DEMs) for military and civilian customers, both inside and outside of the United States. The sensor achieved better than HRTe Level IV position accuracy in near real-time. The system was flown on a deHavilland DHC-7 Army aircraft. This paper presents a collection of images and data products from the Rapid Terrain Visualization interferometric synthetic aperture radar. The imagery includes orthorectified images and DEMs from the RTV interferometric SAR radar.

GLOBECOM '84 - Global Telecommunications Conference, Atlanta, GA, November 26-29, 1984, Conference Record. Volume 3

NASA Astrophysics Data System (ADS)

Attention is given to aspects of quality assurance methodologies in development life cycles, optical intercity transmission systems, multiaccess protocols, system and technology aspects in the case of regional/domestic satellites, advances in SSB-AM radio transmission over terrestrial and satellite network, and development environments for telecommunications systems. Other subjects studied are concerned with business communication networks for voice and data, VLSI in local network and communication protocol, product evaluation and support, an update regarding Videotex, topics in communication theory, topics in radio propagation, a status report regarding societal effects of technology in the workplace, digital image processing, and adaptive signal processing for communications. The management of the reliability function in the development process is considered along with Giga-bit technologies for long distance large capacity optical transmission equipment. The application of gallium arsenide analog and digital integrated circuits for high-speed fiber optical communications, and a simple algorithm for image data coding.

The impact of digital imaging in the field of cytopathology.

PubMed

Pantanowitz, Liron; Hornish, Maryanne; Goulart, Robert A

2009-03-06

With the introduction of digital imaging, pathology is undergoing a digital transformation. In the field of cytology, digital images are being used for telecytology, automated screening of Pap test slides, training and education (e.g. online digital atlases), and proficiency testing. To date, there has been no systematic review on the impact of digital imaging on the practice of cytopathology. This article critically addresses the emerging role of computer-assisted screening and the application of digital imaging to the field of cytology, including telecytology, virtual microscopy, and the impact of online cytology resources. The role of novel diagnostic techniques like image cytometry is also reviewed.

Some technical considerations on the evolution of the IBIS system. [Image Based Information System

NASA Technical Reports Server (NTRS)

Bryant, N. A.; Zobrist, A. L.

1982-01-01

In connection with work related to the use of earth-resources images, it became apparent by 1974, that certain system improvements are necessary for the efficient processing of digital data. To resolve this dilemma, Billingsley and Bryant (1975) proposed the use of image processing technology. Bryant and Zobrist (1976) reported the development of the Image Based Information System (IBIS) as a subset of an overall Video Image Communication and Retrieval (VICAR) image processing system. A description of IBIS is presented, and its employment in connection with advanced applications is discussed. It is concluded that several important lessons have been learned from the development of IBIS. The development of a flexible system such as IBIS is found to rest upon the prior development of a general purpose image processing system, such as VICAR.

Advanced Digital Signal Processing for Hybrid Lidar

DTIC Science & Technology

2014-09-30

with a PC running LabVIEW performing the final calculations to obtain range measurements . A MATLAB- based system developed at Clarkson University in...the image contrast and resolution as well as the object ranging measurement accuracy. There have been various methods that attempt to reduce the...high speed modulation to help suppress backscatter while also providing an unambiguous range measurement . In general, it is desired to determine which

Advanced Patient Data Replication and Recovery

DTIC Science & Technology

2010-10-01

Patient Data Protection (APDAPT) Eisenhower Medical Center (EMC) is attempting to lower the risk of losing patient data, as well as the risk...includes radiological images. EMC has made a multi-million dollar investment in the digitization of patient data; the Electronic Medical Record (EMR...storage and retrieval of the patient chart or EMR. The EMR is comprised of patient vital signs, nurse notes, medications administered, doctors

Automated digital image analysis of islet cell mass using Nikon's inverted eclipse Ti microscope and software to improve engraftment may help to advance the therapeutic efficacy and accessibility of islet transplantation across centers.

PubMed

Gmyr, Valery; Bonner, Caroline; Lukowiak, Bruno; Pawlowski, Valerie; Dellaleau, Nathalie; Belaich, Sandrine; Aluka, Isanga; Moermann, Ericka; Thevenet, Julien; Ezzouaoui, Rimed; Queniat, Gurvan; Pattou, Francois; Kerr-Conte, Julie

2015-01-01

Reliable assessment of islet viability, mass, and purity must be met prior to transplanting an islet preparation into patients with type 1 diabetes. The standard method for quantifying human islet preparations is by direct microscopic analysis of dithizone-stained islet samples, but this technique may be susceptible to inter-/intraobserver variability, which may induce false positive/negative islet counts. Here we describe a simple, reliable, automated digital image analysis (ADIA) technique for accurately quantifying islets into total islet number, islet equivalent number (IEQ), and islet purity before islet transplantation. Islets were isolated and purified from n = 42 human pancreata according to the automated method of Ricordi et al. For each preparation, three islet samples were stained with dithizone and expressed as IEQ number. Islets were analyzed manually by microscopy or automatically quantified using Nikon's inverted Eclipse Ti microscope with built-in NIS-Elements Advanced Research (AR) software. The AIDA method significantly enhanced the number of islet preparations eligible for engraftment compared to the standard manual method (p < 0.001). Comparisons of individual methods showed good correlations between mean values of IEQ number (r(2) = 0.91) and total islet number (r(2) = 0.88) and thus increased to r(2) = 0.93 when islet surface area was estimated comparatively with IEQ number. The ADIA method showed very high intraobserver reproducibility compared to the standard manual method (p < 0.001). However, islet purity was routinely estimated as significantly higher with the manual method versus the ADIA method (p < 0.001). The ADIA method also detected small islets between 10 and 50 µm in size. Automated digital image analysis utilizing the Nikon Instruments software is an unbiased, simple, and reliable teaching tool to comprehensively assess the individual size of each islet cell preparation prior to transplantation. Implementation of this technology to improve engraftment may help to advance the therapeutic efficacy and accessibility of islet transplantation across centers.

Coherent imaging with incoherent light in digital holographic microscopy

NASA Astrophysics Data System (ADS)

Chmelik, Radim

2012-01-01

Digital holographic microscope (DHM) allows for imaging with a quantitative phase contrast. In this way it becomes an important instrument, a completely non-invasive tool for a contrast intravital observation of living cells and a cell drymass density distribution measurement. A serious drawback of current DHMs is highly coherent illumination which makes the lateral resolution worse and impairs the image quality by a coherence noise and a parasitic interference. An uncompromising solution to this problem can be found in the Leith concept of incoherent holography. An off-axis hologram can be formed with arbitrary degree of light coherence in systems equipped with an achromatic interferometer and thus the resolution and the image quality typical for an incoherent-light wide-field microscopy can be achieved. In addition, advanced imaging modes based on limited coherence can be utilized. The typical example is a coherence-gating effect which provides a finite axial resolution and makes DHM image similar to that of a confocal microscope. These possibilities were described theoretically using the formalism of three-dimensional coherent transfer functions and proved experimentally by the coherence-controlled holographic microscope which is DHM based on the Leith achromatic interferometer. Quantitative-phase-contrast imaging is demonstrated with incoherent light by the living cancer cells observation and their motility evaluation. The coherence-gating effect was proved by imaging of model samples through a scattering layer and living cells inside an opalescent medium.

A Novel Texture-Quantization-Based Reversible Multiple Watermarking Scheme Applied to Health Information System.

PubMed

Turuk, Mousami; Dhande, Ashwin

2018-04-01

The recent innovations in information and communication technologies have appreciably changed the panorama of health information system (HIS). These advances provide new means to process, handle, and share medical images and also augment the medical image security issues in terms of confidentiality, reliability, and integrity. Digital watermarking has emerged as new era that offers acceptable solutions to the security issues in HIS. Texture is a significant feature to detect the embedding sites in an image, which further leads to substantial improvement in the robustness. However, considering the perspective of digital watermarking, this feature has received meager attention in the reported literature. This paper exploits the texture property of an image and presents a novel hybrid texture-quantization-based approach for reversible multiple watermarking. The watermarked image quality has been accessed by peak signal to noise ratio (PSNR), structural similarity measure (SSIM), and universal image quality index (UIQI), and the obtained results are superior to the state-of-the-art methods. The algorithm has been evaluated on a variety of medical imaging modalities (CT, MRA, MRI, US) and robustness has been verified, considering various image processing attacks including JPEG compression. The proposed scheme offers additional security using repetitive embedding of BCH encoded watermarks and ADM encrypted ECG signal. Experimental results achieved a maximum of 22,616 bits hiding capacity with PSNR of 53.64 dB.

The Pathologist 2.0: An Update on Digital Pathology in Veterinary Medicine.

PubMed

Bertram, Christof A; Klopfleisch, Robert

2017-09-01

Using light microscopy to describe the microarchitecture of normal and diseased tissues has changed very little since the middle of the 19th century. While the premise of histologic analysis remains intact, our relationship with the microscope is changing dramatically. Digital pathology offers new forms of visualization, and delivery of images is facilitated in unprecedented ways. This new technology can untether us entirely from our light microscopes, with many pathologists already performing their jobs using virtual microscopy. Several veterinary colleges have integrated virtual microscopy in their curriculum, and some diagnostic histopathology labs are switching to virtual microscopy as their main tool for the assessment of histologic specimens. Considering recent technical advancements of slide scanner and viewing software, digital pathology should now be considered a serious alternative to traditional light microscopy. This review therefore intends to give an overview of the current digital pathology technologies and their potential in all fields of veterinary pathology (ie, research, diagnostic service, and education). A future integration of digital pathology in the veterinary pathologist's workflow seems to be inevitable, and therefore it is proposed that trainees should be taught in digital pathology to keep up with the unavoidable digitization of the profession.

Image detection and compression for memory efficient system analysis

NASA Astrophysics Data System (ADS)

Bayraktar, Mustafa

2015-02-01

The advances in digital signal processing have been progressing towards efficient use of memory and processing. Both of these factors can be utilized efficiently by using feasible techniques of image storage by computing the minimum information of image which will enhance computation in later processes. Scale Invariant Feature Transform (SIFT) can be utilized to estimate and retrieve of an image. In computer vision, SIFT can be implemented to recognize the image by comparing its key features from SIFT saved key point descriptors. The main advantage of SIFT is that it doesn't only remove the redundant information from an image but also reduces the key points by matching their orientation and adding them together in different windows of image [1]. Another key property of this approach is that it works on highly contrasted images more efficiently because it`s design is based on collecting key points from the contrast shades of image.

Image compression system and method having optimized quantization tables

NASA Technical Reports Server (NTRS)

Ratnakar, Viresh (Inventor); Livny, Miron (Inventor)

1998-01-01

A digital image compression preprocessor for use in a discrete cosine transform-based digital image compression device is provided. The preprocessor includes a gathering mechanism for determining discrete cosine transform statistics from input digital image data. A computing mechanism is operatively coupled to the gathering mechanism to calculate a image distortion array and a rate of image compression array based upon the discrete cosine transform statistics for each possible quantization value. A dynamic programming mechanism is operatively coupled to the computing mechanism to optimize the rate of image compression array against the image distortion array such that a rate-distortion-optimal quantization table is derived. In addition, a discrete cosine transform-based digital image compression device and a discrete cosine transform-based digital image compression and decompression system are provided. Also, a method for generating a rate-distortion-optimal quantization table, using discrete cosine transform-based digital image compression, and operating a discrete cosine transform-based digital image compression and decompression system are provided.

High spatial resolution mapping of folds and fractures using Unmanned Aerial Vehicle (UAV) photogrammetry

NASA Astrophysics Data System (ADS)

Cruden, A. R.; Vollgger, S.

2016-12-01

The emerging capability of UAV photogrammetry combines a simple and cost-effective method to acquire digital aerial images with advanced computer vision algorithms that compute spatial datasets from a sequence of overlapping digital photographs from various viewpoints. Depending on flight altitude and camera setup, sub-centimeter spatial resolution orthophotographs and textured dense point clouds can be achieved. Orientation data can be collected for detailed structural analysis by digitally mapping such high-resolution spatial datasets in a fraction of time and with higher fidelity compared to traditional mapping techniques. Here we describe a photogrammetric workflow applied to a structural study of folds and fractures within alternating layers of sandstone and mudstone at a coastal outcrop in SE Australia. We surveyed this location using a downward looking digital camera mounted on commercially available multi-rotor UAV that autonomously followed waypoints at a set altitude and speed to ensure sufficient image overlap, minimum motion blur and an appropriate resolution. The use of surveyed ground control points allowed us to produce a geo-referenced 3D point cloud and an orthophotograph from hundreds of digital images at a spatial resolution < 10 mm per pixel, and cm-scale location accuracy. Orientation data of brittle and ductile structures were semi-automatically extracted from these high-resolution datasets using open-source software. This resulted in an extensive and statistically relevant orientation dataset that was used to 1) interpret the progressive development of folds and faults in the region, and 2) to generate a 3D structural model that underlines the complex internal structure of the outcrop and quantifies spatial variations in fold geometries. Overall, our work highlights how UAV photogrammetry can contribute to new insights in structural analysis.

Omniview motionless camera orientation system

NASA Technical Reports Server (NTRS)

Martin, H. Lee (Inventor); Kuban, Daniel P. (Inventor); Zimmermann, Steven D. (Inventor); Busko, Nicholas (Inventor)

2010-01-01

An apparatus and method is provided for converting digital images for use in an imaging system. The apparatus includes a data memory which stores digital data representing an image having a circular or spherical field of view such as an image captured by a fish-eye lens, a control input for receiving a signal for selecting a portion of the image, and a converter responsive to the control input for converting digital data corresponding to the selected portion into digital data representing a planar image for subsequent display. Various methods include the steps of storing digital data representing an image having a circular or spherical field of view, selecting a portion of the image, and converting the stored digital data corresponding to the selected portion into digital data representing a planar image for subsequent display. In various embodiments, the data converter and data conversion step may use an orthogonal set of transformation algorithms.

Different methods of image segmentation in the process of meat marbling evaluation

NASA Astrophysics Data System (ADS)

Ludwiczak, A.; Ślósarz, P.; Lisiak, D.; Przybylak, A.; Boniecki, P.; Stanisz, M.; Koszela, K.; Zaborowicz, M.; Przybył, K.; Wojcieszak, D.; Janczak, D.; Bykowska, M.

2015-07-01

The level of marbling in meat assessment based on digital images is very popular, as computer vision tools are becoming more and more advanced. However considering muscle cross sections as the data source for marbling level evaluation, there are still a few problems to cope with. There is a need for an accurate method which would facilitate this evaluation procedure and increase its accuracy. The presented research was conducted in order to compare the effect of different image segmentation tools considering their usefulness in meat marbling evaluation on the muscle anatomical cross - sections. However this study is considered to be an initial trial in the presented field of research and an introduction to ultrasonic images processing and analysis.

Super Resolution Imaging of the Bottomside Ionosphere with the LWA

NASA Astrophysics Data System (ADS)

Obenberger, K.; Parris, R. T.; Taylor, G. B.; Dowell, J.; Malins, J. B.; Pedersen, T.

2017-12-01

Standard ionospheric sounding instruments typically only utilize a handful HF antennas to receive their transmitted signal, and therefore are limited in their ability to image reflections from the bottomside ionosphere. This limitation is primarily due to the low signal to noise ratio of only a few receiving elements. However, recent advancements in digital processing have ushered in a new era of many-element radio telescopes, capable of sub degree all-sky imaging in the HF band. The Long Wavelength Array station at Sevilleta National Wildlife Refuge, New Mexico (LWA-SV), which was specifically designed with improved HF performance for imaging bottomside propagation, began observations this year. I will discuss the new capabilities and imaging techniques of LWA-SV, and show some preliminary measurements of small scale ionospheric structure.

The Orthanc Ecosystem for Medical Imaging.

PubMed

Jodogne, Sébastien

2018-05-03

This paper reviews the components of Orthanc, a free and open-source, highly versatile ecosystem for medical imaging. At the core of the Orthanc ecosystem, the Orthanc server is a lightweight vendor neutral archive that provides PACS managers with a powerful environment to automate and optimize the imaging flows that are very specific to each hospital. The Orthanc server can be extended with plugins that provide solutions for teleradiology, digital pathology, or enterprise-ready databases. It is shown how software developers and research engineers can easily develop external software or Web portals dealing with medical images, with minimal knowledge of the DICOM standard, thanks to the advanced programming interface of the Orthanc server. The paper concludes by introducing the Stone of Orthanc, an innovative toolkit for the cross-platform rendering of medical images.

Image Format Conversion to DICOM and Lookup Table Conversion to Presentation Value of the Japanese Society of Radiological Technology (JSRT) Standard Digital Image Database.

PubMed

Yanagita, Satoshi; Imahana, Masato; Suwa, Kazuaki; Sugimura, Hitomi; Nishiki, Masayuki

2016-01-01

Japanese Society of Radiological Technology (JSRT) standard digital image database contains many useful cases of chest X-ray images, and has been used in many state-of-the-art researches. However, the pixel values of all the images are simply digitized as relative density values by utilizing a scanned film digitizer. As a result, the pixel values are completely different from the standardized display system input value of digital imaging and communications in medicine (DICOM), called presentation value (P-value), which can maintain a visual consistency when observing images using different display luminance. Therefore, we converted all the images from JSRT standard digital image database to DICOM format followed by the conversion of the pixel values to P-value using an original program developed by ourselves. Consequently, JSRT standard digital image database has been modified so that the visual consistency of images is maintained among different luminance displays.

Overview of telepathology, virtual microscopy, and whole slide imaging: prospects for the future.

PubMed

Weinstein, Ronald S; Graham, Anna R; Richter, Lynne C; Barker, Gail P; Krupinski, Elizabeth A; Lopez, Ana Maria; Erps, Kristine A; Bhattacharyya, Achyut K; Yagi, Yukako; Gilbertson, John R

2009-08-01

Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, fourth-generation telepathology systems, so-called virtual slide telepathology systems, are being used for education applications. Both conventional and innovative surgical pathology diagnostic services are being designed and implemented as well. The technology has been commercialized by more than 30 companies in Asia, the United States, and Europe. Early adopters of telepathology have been laboratories with special challenges in providing anatomic pathology services, ranging from the need to provide anatomic pathology services at great distances to the use of the technology to increase efficiency of services between hospitals less than a mile apart. As to what often happens in medicine, early adopters of new technologies are professionals who create model programs that are successful and then stimulate the creation of infrastructure (ie, reimbursement, telecommunications, information technologies, and so on) that forms the platforms for entry of later, mainstream, adopters. The trend at medical schools, in the United States, is to go entirely digital for their pathology courses, discarding their student light microscopes, and building virtual slide laboratories. This may create a generation of pathology trainees who prefer digital pathology imaging over the traditional hands-on light microscopy. The creation of standards for virtual slide telepathology is early in its development but accelerating. The field of telepathology has now reached a tipping point at which major corporations now investing in the technology will insist that standards be created for pathology digital imaging as a value added business proposition. A key to success in teleradiology, already a growth industry, has been the implementation of standards for digital radiology imaging. Telepathology is already the enabling technology for new, innovative laboratory services. Examples include STAT QA surgical pathology second opinions at a distance and a telehealth-enabled rapid breast care service. The innovative bundling of telemammography, telepathology, and teleoncology services may represent a new paradigm in breast care that helps address the serious issue of fragmentation of breast cancer care in the United States and elsewhere. Legal and regulatory issues in telepathology are being addressed and are regarded as a potential catalyst for the next wave of telepathology advances, applications, and implementations.

3D Digital Surveying and Modelling of Cave Geometry: Application to Paleolithic Rock Art.

PubMed

González-Aguilera, Diego; Muñoz-Nieto, Angel; Gómez-Lahoz, Javier; Herrero-Pascual, Jesus; Gutierrez-Alonso, Gabriel

2009-01-01

3D digital surveying and modelling of cave geometry represents a relevant approach for research, management and preservation of our cultural and geological legacy. In this paper, a multi-sensor approach based on a terrestrial laser scanner, a high-resolution digital camera and a total station is presented. Two emblematic caves of Paleolithic human occupation and situated in northern Spain, "Las Caldas" and "Peña de Candamo", have been chosen to put in practise this approach. As a result, an integral and multi-scalable 3D model is generated which may allow other scientists, pre-historians, geologists…, to work on two different levels, integrating different Paleolithic Art datasets: (1) a basic level based on the accurate and metric support provided by the laser scanner; and (2) a advanced level using the range and image-based modelling.

Theoretical and Monte Carlo optimization of a stacked three-layer flat-panel x-ray imager for applications in multi-spectral diagnostic medical imaging

NASA Astrophysics Data System (ADS)

Lopez Maurino, Sebastian; Badano, Aldo; Cunningham, Ian A.; Karim, Karim S.

2016-03-01

We propose a new design of a stacked three-layer flat-panel x-ray detector for dual-energy (DE) imaging. Each layer consists of its own scintillator of individual thickness and an underlying thin-film-transistor-based flat-panel. Three images are obtained simultaneously in the detector during the same x-ray exposure, thereby eliminating any motion artifacts. The detector operation is two-fold: a conventional radiography image can be obtained by combining all three layers' images, while a DE subtraction image can be obtained from the front and back layers' images, where the middle layer acts as a mid-filter that helps achieve spectral separation. We proceed to optimize the detector parameters for two sample imaging tasks that could particularly benefit from this new detector by obtaining the best possible signal to noise ratio per root entrance exposure using well-established theoretical models adapted to fit our new design. These results are compared to a conventional DE temporal subtraction detector and a single-shot DE subtraction detector with a copper mid-filter, both of which underwent the same theoretical optimization. The findings are then validated using advanced Monte Carlo simulations for all optimized detector setups. Given the performance expected from initial results and the recent decrease in price for digital x-ray detectors, the simplicity of the three-layer stacked imager approach appears promising to usher in a new generation of multi-spectral digital x-ray diagnostics.

Predictive images of postoperative levator resection outcome using image processing software.

PubMed

Mawatari, Yuki; Fukushima, Mikiko

2016-01-01

This study aims to evaluate the efficacy of processed images to predict postoperative appearance following levator resection. Analysis involved 109 eyes from 65 patients with blepharoptosis who underwent advancement of levator aponeurosis and Müller's muscle complex (levator resection). Predictive images were prepared from preoperative photographs using the image processing software (Adobe Photoshop ® ). Images of selected eyes were digitally enlarged in an appropriate manner and shown to patients prior to surgery. Approximately 1 month postoperatively, we surveyed our patients using questionnaires. Fifty-six patients (89.2%) were satisfied with their postoperative appearances, and 55 patients (84.8%) positively responded to the usefulness of processed images to predict postoperative appearance. Showing processed images that predict postoperative appearance to patients prior to blepharoptosis surgery can be useful for those patients concerned with their postoperative appearance. This approach may serve as a useful tool to simulate blepharoptosis surgery.

Predictive images of postoperative levator resection outcome using image processing software

PubMed Central

Mawatari, Yuki; Fukushima, Mikiko

2016-01-01

Purpose This study aims to evaluate the efficacy of processed images to predict postoperative appearance following levator resection. Methods Analysis involved 109 eyes from 65 patients with blepharoptosis who underwent advancement of levator aponeurosis and Müller’s muscle complex (levator resection). Predictive images were prepared from preoperative photographs using the image processing software (Adobe Photoshop®). Images of selected eyes were digitally enlarged in an appropriate manner and shown to patients prior to surgery. Results Approximately 1 month postoperatively, we surveyed our patients using questionnaires. Fifty-six patients (89.2%) were satisfied with their postoperative appearances, and 55 patients (84.8%) positively responded to the usefulness of processed images to predict postoperative appearance. Conclusion Showing processed images that predict postoperative appearance to patients prior to blepharoptosis surgery can be useful for those patients concerned with their postoperative appearance. This approach may serve as a useful tool to simulate blepharoptosis surgery. PMID:27757008

Imaging and Analytics: The changing face of Medical Imaging

NASA Astrophysics Data System (ADS)

Foo, Thomas

There have been significant technological advances in imaging capability over the past 40 years. Medical imaging capabilities have developed rapidly, along with technology development in computational processing speed and miniaturization. Moving to all-digital, the number of images that are acquired in a routine clinical examination has increased dramatically from under 50 images in the early days of CT and MRI to more than 500-1000 images today. The staggering number of images that are routinely acquired poses significant challenges for clinicians to interpret the data and to correctly identify the clinical problem. Although the time provided to render a clinical finding has not substantially changed, the amount of data available for interpretation has grown exponentially. In addition, the image quality (spatial resolution) and information content (physiologically-dependent image contrast) has also increased significantly with advances in medical imaging technology. On its current trajectory, medical imaging in the traditional sense is unsustainable. To assist in filtering and extracting the most relevant data elements from medical imaging, image analytics will have a much larger role. Automated image segmentation, generation of parametric image maps, and clinical decision support tools will be needed and developed apace to allow the clinician to manage, extract and utilize only the information that will help improve diagnostic accuracy and sensitivity. As medical imaging devices continue to improve in spatial resolution, functional and anatomical information content, image/data analytics will be more ubiquitous and integral to medical imaging capability.

Digital Imaging

NASA Technical Reports Server (NTRS)

1986-01-01

Digital Imaging is the computer processed numerical representation of physical images. Enhancement of images results in easier interpretation. Quantitative digital image analysis by Perceptive Scientific Instruments, locates objects within an image and measures them to extract quantitative information. Applications are CAT scanners, radiography, microscopy in medicine as well as various industrial and manufacturing uses. The PSICOM 327 performs all digital image analysis functions. It is based on Jet Propulsion Laboratory technology, is accurate and cost efficient.

Design of Digital Phase-Locked Loops For Advanced Digital Transponders

NASA Technical Reports Server (NTRS)

Nguyen, Tien M.

1994-01-01

For advanced digital space transponders, the Digital Phased-Locked Loops (DPLLs) can be designed using the available analog loops. DPLLs considered in this paper are derived from the Analog Phase-Locked Loop (APLL) using S-domain mapping techniques.

Mars Cameras Make Panoramic Photography a Snap

NASA Technical Reports Server (NTRS)

2008-01-01

If you wish to explore a Martian landscape without leaving your armchair, a few simple clicks around the NASA Web site will lead you to panoramic photographs taken from the Mars Exploration Rovers, Spirit and Opportunity. Many of the technologies that enable this spectacular Mars photography have also inspired advancements in photography here on Earth, including the panoramic camera (Pancam) and its housing assembly, designed by the Jet Propulsion Laboratory and Cornell University for the Mars missions. Mounted atop each rover, the Pancam mast assembly (PMA) can tilt a full 180 degrees and swivel 360 degrees, allowing for a complete, highly detailed view of the Martian landscape. The rover Pancams take small, 1 megapixel (1 million pixel) digital photographs, which are stitched together into large panoramas that sometimes measure 4 by 24 megapixels. The Pancam software performs some image correction and stitching after the photographs are transmitted back to Earth. Different lens filters and a spectrometer also assist scientists in their analyses of infrared radiation from the objects in the photographs. These photographs from Mars spurred developers to begin thinking in terms of larger and higher quality images: super-sized digital pictures, or gigapixels, which are images composed of 1 billion or more pixels. Gigapixel images are more than 200 times the size captured by today s standard 4 megapixel digital camera. Although originally created for the Mars missions, the detail provided by these large photographs allows for many purposes, not all of which are limited to extraterrestrial photography.

Blurred digital mammography images: an analysis of technical recall and observer detection performance.

PubMed

Ma, Wang Kei; Borgen, Rita; Kelly, Judith; Millington, Sara; Hilton, Beverley; Aspin, Rob; Lança, Carla; Hogg, Peter

2017-03-01

Blurred images in full-field digital mammography are a problem in the UK Breast Screening Programme. Technical recalls may be due to blurring not being seen on lower resolution monitors used for review. This study assesses the visual detection of blurring on a 2.3-MP monitor and a 5-MP report grade monitor and proposes an observer standard for the visual detection of blurring on a 5-MP reporting grade monitor. 28 observers assessed 120 images for blurring; 20 images had no blurring present, whereas 100 images had blurring imposed through mathematical simulation at 0.2, 0.4, 0.6, 0.8 and 1.0 mm levels of motion. Technical recall rate for both monitors and angular size at each level of motion were calculated. χ 2 tests were used to test whether significant differences in blurring detection existed between 2.3- and 5-MP monitors. The technical recall rate for 2.3- and 5-MP monitors are 20.3% and 9.1%, respectively. The angular size for 0.2- to 1-mm motion varied from 55 to 275 arc s. The minimum amount of motion for visual detection of blurring in this study is 0.4 mm. For 0.2-mm simulated motion, there was no significant difference [χ 2 (1, N = 1095) = 1.61, p = 0.20] in blurring detection between the 2.3- and 5-MP monitors. According to this study, monitors ≤2.3 MP are not suitable for technical review of full-field digital mammography images for the detection of blur. Advances in knowledge: This research proposes the first observer standard for the visual detection of blurring.

Blurred digital mammography images: an analysis of technical recall and observer detection performance

PubMed Central

Borgen, Rita; Kelly, Judith; Millington, Sara; Hilton, Beverley; Aspin, Rob; Lança, Carla; Hogg, Peter

2017-01-01

Objective: Blurred images in full-field digital mammography are a problem in the UK Breast Screening Programme. Technical recalls may be due to blurring not being seen on lower resolution monitors used for review. This study assesses the visual detection of blurring on a 2.3-MP monitor and a 5-MP report grade monitor and proposes an observer standard for the visual detection of blurring on a 5-MP reporting grade monitor. Methods: 28 observers assessed 120 images for blurring; 20 images had no blurring present, whereas 100 images had blurring imposed through mathematical simulation at 0.2, 0.4, 0.6, 0.8 and 1.0 mm levels of motion. Technical recall rate for both monitors and angular size at each level of motion were calculated. χ2 tests were used to test whether significant differences in blurring detection existed between 2.3- and 5-MP monitors. Results: The technical recall rate for 2.3- and 5-MP monitors are 20.3% and 9.1%, respectively. The angular size for 0.2- to 1-mm motion varied from 55 to 275 arc s. The minimum amount of motion for visual detection of blurring in this study is 0.4 mm. For 0.2-mm simulated motion, there was no significant difference [χ2 (1, N = 1095) = 1.61, p = 0.20] in blurring detection between the 2.3- and 5-MP monitors. Conclusion: According to this study, monitors ≤2.3 MP are not suitable for technical review of full-field digital mammography images for the detection of blur. Advances in knowledge: This research proposes the first observer standard for the visual detection of blurring. PMID:28134567

Automated Ground-based Time-lapse Camera Monitoring of West Greenland ice sheet outlet Glaciers: Challenges and Solutions

NASA Astrophysics Data System (ADS)

Ahn, Y.; Box, J. E.; Balog, J.; Lewinter, A.

2008-12-01

Monitoring Greenland outlet glaciers using remotely sensed data has drawn a great attention in earth science communities for decades and time series analysis of sensory data has provided important variability information of glacier flow by detecting speed and thickness changes, tracking features and acquiring model input. Thanks to advancements of commercial digital camera technology and increased solid state storage, we activated automatic ground-based time-lapse camera stations with high spatial/temporal resolution in west Greenland outlet and collected one-hour interval data continuous for more than one year at some but not all sites. We believe that important information of ice dynamics are contained in these data and that terrestrial mono-/stereo-photogrammetry can provide theoretical/practical fundamentals in data processing along with digital image processing techniques. Time-lapse images over periods in west Greenland indicate various phenomenon. Problematic is rain, snow, fog, shadows, freezing of water on camera enclosure window, image over-exposure, camera motion, sensor platform drift, and fox chewing of instrument cables, and the pecking of plastic window by ravens. Other problems include: feature identification, camera orientation, image registration, feature matching in image pairs, and feature tracking. Another obstacle is that non-metric digital camera contains large distortion to be compensated for precise photogrammetric use. Further, a massive number of images need to be processed in a way that is sufficiently computationally efficient. We meet these challenges by 1) identifying problems in possible photogrammetric processes, 2) categorizing them based on feasibility, and 3) clarifying limitation and alternatives, while emphasizing displacement computation and analyzing regional/temporal variability. We experiment with mono and stereo photogrammetric techniques in the aide of automatic correlation matching for efficiently handling the enormous data volumes.

Development of an MRI-compatible digital SiPM detector stack for simultaneous PET/MRI.

PubMed

Düppenbecker, Peter M; Weissler, Bjoern; Gebhardt, Pierre; Schug, David; Wehner, Jakob; Marsden, Paul K; Schulz, Volkmar

2016-02-01

Advances in solid-state photon detectors paved the way to combine positron emission tomography (PET) and magnetic resonance imaging (MRI) into highly integrated, truly simultaneous, hybrid imaging systems. Based on the most recent digital SiPM technology, we developed an MRI-compatible PET detector stack, intended as a building block for next generation simultaneous PET/MRI systems. Our detector stack comprises an array of 8 × 8 digital SiPM channels with 4 mm pitch using Philips Digital Photon Counting DPC 3200-22 devices, an FPGA for data acquisition, a supply voltage control system and a cooling infrastructure. This is the first detector design that allows the operation of digital SiPMs simultaneously inside an MRI system. We tested and optimized the MRI-compatibility of our detector stack on a laboratory test bench as well as in combination with a Philips Achieva 3 T MRI system. Our design clearly reduces distortions of the static magnetic field compared to a conventional design. The MRI static magnetic field causes weak and directional drift effects on voltage regulators, but has no direct impact on detector performance. MRI gradient switching initially degraded energy and timing resolution. Both distortions could be ascribed to voltage variations induced on the bias and the FPGA core voltage supply respectively. Based on these findings, we improved our detector design and our final design shows virtually no energy or timing degradations, even during heavy and continuous MRI gradient switching. In particular, we found no evidence that the performance of the DPC 3200-22 digital SiPM itself is degraded by the MRI system.

HIPAA, dermatology images, and the law.

PubMed

Scheinfeld, Noah; Rothstein, Brooke

2013-12-01

From smart phones to iPads, the world has grown increasingly reliant on new technology. In this ever-expanding digital age, medicine is at the forefront of these new technologies. In the field of dermatology and general medicine, digital images have become an important tool used in patient management. Today, one can even find physicians who use their cellular phone cameras to take patient images and transmit them to other physicians. However, as digital imaging technology has become more prevalent so too have concerns about the impact of this technology on the electronic medical record, quality of patient care, and medicolegal issues. This article will discuss the advent of digital imaging technology in dermatology and the legal ramifications digital images have on medical care, abiding by HIPAA, the use of digital images as evidence, and the possible abuses digital images can pose in a health care setting.

Mini gamma camera, camera system and method of use

DOEpatents

Majewski, Stanislaw; Weisenberger, Andrew G.; Wojcik, Randolph F.

2001-01-01

A gamma camera comprising essentially and in order from the front outer or gamma ray impinging surface: 1) a collimator, 2) a scintillator layer, 3) a light guide, 4) an array of position sensitive, high resolution photomultiplier tubes, and 5) printed circuitry for receipt of the output of the photomultipliers. There is also described, a system wherein the output supplied by the high resolution, position sensitive photomultipiler tubes is communicated to: a) a digitizer and b) a computer where it is processed using advanced image processing techniques and a specific algorithm to calculate the center of gravity of any abnormality observed during imaging, and c) optional image display and telecommunications ports.

High data volume and transfer rate techniques used at NASA's image processing facility

NASA Technical Reports Server (NTRS)

Heffner, P.; Connell, E.; Mccaleb, F.

1978-01-01

Data storage and transfer operations at a new image processing facility are described. The equipment includes high density digital magnetic tape drives and specially designed controllers to provide an interface between the tape drives and computerized image processing systems. The controller performs the functions necessary to convert the continuous serial data stream from the tape drive to a word-parallel blocked data stream which then goes to the computer-based system. With regard to the tape packing density, 1.8 times 10 to the tenth data bits are stored on a reel of one-inch tape. System components and their operation are surveyed, and studies on advanced storage techniques are summarized.

The tissue microarray data exchange specification: Extending TMA DES to provide flexible scoring and incorporate virtual slides

PubMed Central

Wright, Alexander; Lyttleton, Oliver; Lewis, Paul; Quirke, Philip; Treanor, Darren

2011-01-01

Background: Tissue MicroArrays (TMAs) are a high throughput technology for rapid analysis of protein expression across hundreds of patient samples. Often, data relating to TMAs is specific to the clinical trial or experiment it is being used for, and not interoperable. The Tissue Microarray Data Exchange Specification (TMA DES) is a set of eXtensible Markup Language (XML)-based protocols for storing and sharing digitized Tissue Microarray data. XML data are enclosed by named tags which serve as identifiers. These tag names can be Common Data Elements (CDEs), which have a predefined meaning or semantics. By using this specification in a laboratory setting with increasing demands for digital pathology integration, we found that the data structure lacked the ability to cope with digital slide imaging in respect to web-enabled digital pathology systems and advanced scoring techniques. Materials and Methods: By employing user centric design, and observing behavior in relation to TMA scoring and associated data, the TMA DES format was extended to accommodate the current limitations. This was done with specific focus on developing a generic tool for handling any given scoring system, and utilizing data for multiple observations and observers. Results: DTDs were created to validate the extensions of the TMA DES protocol, and a test set of data containing scores for 6,708 TMA core images was generated. The XML was then read into an image processing algorithm to utilize the digital pathology data extensions, and scoring results were easily stored alongside the existing multiple pathologist scores. Conclusions: By extending the TMA DES format to include digital pathology data and customizable scoring systems for TMAs, the new system facilitates the collaboration between pathologists and organizations, and can be used in automatic or manual data analysis. This allows complying systems to effectively communicate complex and varied scoring data. PMID:21572508

Advanced illumination control algorithm for medical endoscopy applications

NASA Astrophysics Data System (ADS)

Sousa, Ricardo M.; Wäny, Martin; Santos, Pedro; Morgado-Dias, F.

2015-05-01

CMOS image sensor manufacturer, AWAIBA, is providing the world's smallest digital camera modules to the world market for minimally invasive surgery and one time use endoscopic equipment. Based on the world's smallest digital camera head and the evaluation board provided to it, the aim of this paper is to demonstrate an advanced fast response dynamic control algorithm of the illumination LED source coupled to the camera head, over the LED drivers embedded on the evaluation board. Cost efficient and small size endoscopic camera modules nowadays embed minimal size image sensors capable of not only adjusting gain and exposure time but also LED illumination with adjustable illumination power. The LED illumination power has to be dynamically adjusted while navigating the endoscope over changing illumination conditions of several orders of magnitude within fractions of the second to guarantee a smooth viewing experience. The algorithm is centered on the pixel analysis of selected ROIs enabling it to dynamically adjust the illumination intensity based on the measured pixel saturation level. The control core was developed in VHDL and tested in a laboratory environment over changing light conditions. The obtained results show that it is capable of achieving correction speeds under 1 s while maintaining a static error below 3% relative to the total number of pixels on the image. The result of this work will allow the integration of millimeter sized high brightness LED sources on minimal form factor cameras enabling its use in endoscopic surgical robotic or micro invasive surgery.

New Embedded Denotes Fuzzy C-Mean Application for Breast Cancer Density Segmentation in Digital Mammograms

NASA Astrophysics Data System (ADS)

Othman, Khairulnizam; Ahmad, Afandi

2016-11-01

In this research we explore the application of normalize denoted new techniques in advance fast c-mean in to the problem of finding the segment of different breast tissue regions in mammograms. The goal of the segmentation algorithm is to see if new denotes fuzzy c- mean algorithm could separate different densities for the different breast patterns. The new density segmentation is applied with multi-selection of seeds label to provide the hard constraint, whereas the seeds labels are selected based on user defined. New denotes fuzzy c- mean have been explored on images of various imaging modalities but not on huge format digital mammograms just yet. Therefore, this project is mainly focused on using normalize denoted new techniques employed in fuzzy c-mean to perform segmentation to increase visibility of different breast densities in mammography images. Segmentation of the mammogram into different mammographic densities is useful for risk assessment and quantitative evaluation of density changes. Our proposed methodology for the segmentation of mammograms on the basis of their region into different densities based categories has been tested on MIAS database and Trueta Database.

Day/night whole sky imagers for 24-h cloud and sky assessment: history and overview.

PubMed

Shields, Janet E; Karr, Monette E; Johnson, Richard W; Burden, Art R

2013-03-10

A family of fully automated digital whole sky imagers (WSIs) has been developed at the Marine Physical Laboratory over many years, for a variety of research and military applications. The most advanced of these, the day/night whole sky imagers (D/N WSIs), acquire digital imagery of the full sky down to the horizon under all conditions from full sunlight to starlight. Cloud algorithms process the imagery to automatically detect the locations of cloud for both day and night. The instruments can provide absolute radiance distribution over the full radiance range from starlight through daylight. The WSIs were fielded in 1984, followed by the D/N WSIs in 1992. These many years of experience and development have resulted in very capable instruments and algorithms that remain unique. This article discusses the history of the development of the D/N WSIs, system design, algorithms, and data products. The paper cites many reports with more detailed technical documentation. Further details of calibration, day and night algorithms, and cloud free line-of-sight results will be discussed in future articles.

Image processing techniques for digital orthophotoquad production

USGS Publications Warehouse

Hood, Joy J.; Ladner, L. J.; Champion, Richard A.

1989-01-01

Orthophotographs have long been recognized for their value as supplements or alternatives to standard maps. Recent trends towards digital cartography have resulted in efforts by the US Geological Survey to develop a digital orthophotoquad production system. Digital image files were created by scanning color infrared photographs on a microdensitometer. Rectification techniques were applied to remove tile and relief displacement, thereby creating digital orthophotos. Image mosaicking software was then used to join the rectified images, producing digital orthophotos in quadrangle format.

Ultrasonic image analysis and image-guided interventions.

PubMed

Noble, J Alison; Navab, Nassir; Becher, H

2011-08-06

The fields of medical image analysis and computer-aided interventions deal with reducing the large volume of digital images (X-ray, computed tomography, magnetic resonance imaging (MRI), positron emission tomography and ultrasound (US)) to more meaningful clinical information using software algorithms. US is a core imaging modality employed in these areas, both in its own right and used in conjunction with the other imaging modalities. It is receiving increased interest owing to the recent introduction of three-dimensional US, significant improvements in US image quality, and better understanding of how to design algorithms which exploit the unique strengths and properties of this real-time imaging modality. This article reviews the current state of art in US image analysis and its application in image-guided interventions. The article concludes by giving a perspective from clinical cardiology which is one of the most advanced areas of clinical application of US image analysis and describing some probable future trends in this important area of ultrasonic imaging research.

Observations of breakup processes of liquid jets using real-time X-ray radiography

NASA Technical Reports Server (NTRS)

Char, J. M.; Kuo, K. K.; Hsieh, K. C.

1988-01-01

To unravel the liquid-jet breakup process in the nondilute region, a newly developed system of real-time X-ray radiography, an advanced digital image processor, and a high-speed video camera were used. Based upon recorded X-ray images, the inner structure of a liquid jet during breakup was observed. The jet divergence angle, jet breakup length, and fraction distributions along the axial and transverse directions of the liquid jets were determined in the near-injector region. Both wall- and free-jet tests were conducted to study the effect of wall friction on the jet breakup process.

Simultaneous single-shot readout of multi-qubit circuits using a traveling-wave parametric amplifier

NASA Astrophysics Data System (ADS)

O'Brien, Kevin

Observing and controlling the state of ever larger quantum systems is critical for advancing quantum computation. Utilizing a Josephson traveling wave parametric amplifier (JTWPA), we demonstrate simultaneous multiplexed single shot readout of 10 transmon qubits in a planar architecture. We employ digital image sideband rejection to eliminate noise at the image frequencies. We quantify crosstalk and infidelity due to simultaneous readout and control of multiple qubits. Based on current amplifier technology, this approach can scale to simultaneous readout of at least 20 qubits. This work was supported by the Army Research Office.

Advanced Digital Signal Processing for Hybrid Lidar FY 2014

DTIC Science & Technology

2014-10-30

processing steps on raw data, with a PC miming Lab VIEW performing the fmal calculations to obtain range measurements . A MATLAB- based system...regarding the object and it reduces the image contrast and resolution as well as the object ranging measurement accuracy. There have been various...frequency (>100MHz) approach that uses high speed modulation to help suppress backscatter while also providing an unambiguous range measurement . In general

CDR Altman and MS Massimino in airlock prior to EVA 4

NASA Image and Video Library

2002-03-07

STS109-E-5688 (7 March 2002) --- Astronaut Scott D. Altman, mission commander, assists astronaut Michael J. Massimino, mission specialist, with suit-donning tasks prior to the STS-109 mission's fourth space walk (EVA-4). Astronauts Massimino and James H. Newman went on to install the new Advanced Camera for Surveys (ACS) on the Hubble Space Telescope (HST). The image was recorded with a digital still camera.

Validation of the international labour office digitized standard images for recognition and classification of radiographs of pneumoconiosis.

PubMed

Halldin, Cara N; Petsonk, Edward L; Laney, A Scott

2014-03-01

Chest radiographs are recommended for prevention and detection of pneumoconiosis. In 2011, the International Labour Office (ILO) released a revision of the International Classification of Radiographs of Pneumoconioses that included a digitized standard images set. The present study compared results of classifications of digital chest images performed using the new ILO 2011 digitized standard images to classification approaches used in the past. Underground coal miners (N = 172) were examined using both digital and film-screen radiography (FSR) on the same day. Seven National Institute for Occupational Safety and Health-certified B Readers independently classified all 172 digital radiographs, once using the ILO 2011 digitized standard images (DRILO2011-D) and once using digitized standard images used in the previous research (DRRES). The same seven B Readers classified all the miners' chest films using the ILO film-based standards. Agreement between classifications of FSR and digital radiography was identical, using a standard image set (either DRILO2011-D or DRRES). The overall weighted κ value was 0.58. Some specific differences in the results were seen and noted. However, intrareader variability in this study was similar to the published values and did not appear to be affected by the use of the new ILO 2011 digitized standard images. These findings validate the use of the ILO digitized standard images for classification of small pneumoconiotic opacities. When digital chest radiographs are obtained and displayed appropriately, results of pneumoconiosis classifications using the 2011 ILO digitized standards are comparable to film-based ILO classifications and to classifications using earlier research standards. Published by Elsevier Inc.

Progress in the capture, manipulation, and delivery of medical media and its impact on education, clinical care, and research.

PubMed

Bernardo, Theresa M; Malinowski, Robert P

2005-01-01

In this article, advances in the application of medical media to education, clinical care, and research are explored and illustrated with examples, and their future potential is discussed. Impact is framed in terms of the Sloan Consortium's five pillars of quality education: access; student and faculty satisfaction; learning effectiveness; and cost effectiveness. (Hiltz SR, Zhang Y, Turoff M. Studies of effectiveness of learning networks. In Bourne J, Moore J, ed. Elements of Quality Online Education. Needham, MA: Sloan-Consortium, 2002:15-45). The alternatives for converting analog media (text, photos, graphics, sound, video, animations, radiographs) to digital media and direct digital capture are covered, as are options for storing, manipulating, retrieving, and sharing digital collections. Diagnostic imaging is given particular attention, clarifying the difference between computerized radiography and digital radiography and explaining the accepted standard (DICOM) and the advantages of Web PACS. Some novel research applications of medical media are presented.

Digitization and Position Measurement of Astronomical Plates of Saturnian Satellites

NASA Astrophysics Data System (ADS)

Yan, D.; Yu, Y.; Zhang, H. Y.; Qiao, R. C.

2014-05-01

Using the advanced commercial scanners to digitize astronomical plates may be a simple and effective way. In this paper, we discuss the method of digitizing and astrometrically reducing six astronomical plates of Saturnian satellites, which were taken from the 1 m RCC (Ritchey Chretien Coude) telescope of Yunnan Observatory in 1988, by using the 10000XL scanner of Epson. The digitized images of the astronomical plates of Saturnian satellites are re-reduced, and the positions of Saturnian satellites based on the UCAC2 (The Second US Naval Observatory CCD Astrograph Catalog) catalogue are given. A comparison of our measured positions with the IMCCE (Institut de Mecanique Celeste et de Calcul des Ephemerides) ephemeris of Saturnian satellites shows the high quality of our measurements, which have an accuracy of 106 mas in right ascension and 89 mas in declination. Moreover, our measurements appear to be consistent with this ephemeris within only about 56 mas in right ascension and 9 mas in declination.

2D and 3D registration methods for dual-energy contrast-enhanced digital breast tomosynthesis

NASA Astrophysics Data System (ADS)

Lau, Kristen C.; Roth, Susan; Maidment, Andrew D. A.

2014-03-01

Contrast-enhanced digital breast tomosynthesis (CE-DBT) uses an iodinated contrast agent to image the threedimensional breast vasculature. The University of Pennsylvania is conducting a CE-DBT clinical study in patients with known breast cancers. The breast is compressed continuously and imaged at four time points (1 pre-contrast; 3 postcontrast). A hybrid subtraction scheme is proposed. First, dual-energy (DE) images are obtained by a weighted logarithmic subtraction of the high-energy and low-energy image pairs. Then, post-contrast DE images are subtracted from the pre-contrast DE image. This hybrid temporal subtraction of DE images is performed to analyze iodine uptake, but suffers from motion artifacts. Employing image registration further helps to correct for motion, enhancing the evaluation of vascular kinetics. Registration using ANTS (Advanced Normalization Tools) is performed in an iterative manner. Mutual information optimization first corrects large-scale motions. Normalized cross-correlation optimization then iteratively corrects fine-scale misalignment. Two methods have been evaluated: a 2D method using a slice-by-slice approach, and a 3D method using a volumetric approach to account for out-of-plane breast motion. Our results demonstrate that iterative registration qualitatively improves with each iteration (five iterations total). Motion artifacts near the edge of the breast are corrected effectively and structures within the breast (e.g. blood vessels, surgical clip) are better visualized. Statistical and clinical evaluations of registration accuracy in the CE-DBT images are ongoing.

42 CFR 37.44 - Approval of radiographic facilities that use digital radiography systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... image acquisition, digitization, processing, compression, transmission, display, archiving, and... quality digital chest radiographs by submitting to NIOSH digital radiographic image files of a test object... digital radiographic image files from six or more sample chest radiographs that are of acceptable quality...

42 CFR 37.44 - Approval of radiographic facilities that use digital radiography systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... image acquisition, digitization, processing, compression, transmission, display, archiving, and... quality digital chest radiographs by submitting to NIOSH digital radiographic image files of a test object... digital radiographic image files from six or more sample chest radiographs that are of acceptable quality...

Three-dimensional imaging of hold baggage for airport security

NASA Astrophysics Data System (ADS)

Kolokytha, S.; Speller, R.; Robson, S.

2014-06-01

This study describes a cost-effective check-in baggage screening system, based on "on-belt tomosynthesis" (ObT) and close-range photogrammetry, that is designed to address the limitations of the most common system used, conventional projection radiography. The latter's limitations can lead to loss of information and an increase in baggage handling time, as baggage is manually searched or screened with more advanced systems. This project proposes a system that overcomes such limitations creating a cost-effective automated pseudo-3D imaging system, by combining x-ray and optical imaging to form digital tomograms. Tomographic reconstruction requires a knowledge of the change in geometry between multiple x-ray views of a common object. This is uniquely achieved using a close range photogrammetric system based on a small network of web-cameras. This paper presents the recent developments of the ObT system and describes recent findings of the photogrammetric system implementation. Based on these positive results, future work on the advancement of the ObT system as a cost-effective pseudo-3D imaging of hold baggage for airport security is proposed.

[Big data in imaging].

PubMed

Sewerin, Philipp; Ostendorf, Benedikt; Hueber, Axel J; Kleyer, Arnd

2018-04-01

Until now, most major medical advancements have been achieved through hypothesis-driven research within the scope of clinical trials. However, due to a multitude of variables, only a certain number of research questions could be addressed during a single study, thus rendering these studies expensive and time consuming. Big data acquisition enables a new data-based approach in which large volumes of data can be used to investigate all variables, thus opening new horizons. Due to universal digitalization of the data as well as ever-improving hard- and software solutions, imaging would appear to be predestined for such analyses. Several small studies have already demonstrated that automated analysis algorithms and artificial intelligence can identify pathologies with high precision. Such automated systems would also seem well suited for rheumatology imaging, since a method for individualized risk stratification has long been sought for these patients. However, despite all the promising options, the heterogeneity of the data and highly complex regulations covering data protection in Germany would still render a big data solution for imaging difficult today. Overcoming these boundaries is challenging, but the enormous potential advances in clinical management and science render pursuit of this goal worthwhile.

Study of optical techniques for the Ames unitary wind tunnel: Digital image processing, part 6

NASA Technical Reports Server (NTRS)

Lee, George

1993-01-01

A survey of digital image processing techniques and processing systems for aerodynamic images has been conducted. These images covered many types of flows and were generated by many types of flow diagnostics. These include laser vapor screens, infrared cameras, laser holographic interferometry, Schlieren, and luminescent paints. Some general digital image processing systems, imaging networks, optical sensors, and image computing chips were briefly reviewed. Possible digital imaging network systems for the Ames Unitary Wind Tunnel were explored.

Initial experience with computer aided detection for microcalcification in digital breast tomosynthesis

NASA Astrophysics Data System (ADS)

Harkness, E. F.; Lim, Y. Y.; Wilson, M. W.; Haq, R.; Zhou, J.; Tate, C.; Maxwell, A. J.; Astley, S. M.; Gilbert, F. J.

2015-03-01

Digital breast tomosynthesis (DBT) addresses limitations of 2-D projection imaging for detection of masses. Microcalcification clusters may be more difficult to appreciate in DBT as individual calcifications within clusters may appear on different slices. This research aims to evaluate the performance of ImageChecker 3D Calc CAD v1.0. Women were recruited as part of the TOMMY trial. From the trial, 169 were included in this study. The DBT images were processed with the computer aided detection (CAD) algorithm. Three consultant radiologists reviewed the images and recorded whether CAD prompts were on or off target. 79/80 (98.8%) malignant cases had a prompt on the area of microcalcification. In these cases, there were 1-15 marks (median 5) with the majority of false prompts (n=326/431) due to benign (68%) and vascular (24%) calcifications. Of 89 normal/benign cases, there were 1-13 prompts (median 3), 27 (30%) had no prompts and the majority of false prompts (n=238) were benign (77%) calcifications. CAD is effective in prompting malignant microcalcification clusters and may overcome the difficulty of detecting clusters in slice images. Although there was a high rate of false prompts, further advances in the software may improve specificity.

Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining, and Automated Image Analysis

PubMed Central

Isse, Kumiko; Lesniak, Andrew; Grama, Kedar; Roysam, Badrinath; Minervini, Martha I.; Demetris, Anthony J

2013-01-01

Conventional histopathology is the gold standard for allograft monitoring, but its value proposition is increasingly questioned. “-Omics” analysis of tissues, peripheral blood and fluids and targeted serologic studies provide mechanistic insights into allograft injury not currently provided by conventional histology. Microscopic biopsy analysis, however, provides valuable and unique information: a) spatial-temporal relationships; b) rare events/cells; c) complex structural context; and d) integration into a “systems” model. Nevertheless, except for immunostaining, no transformative advancements have “modernized” routine microscopy in over 100 years. Pathologists now team with hardware and software engineers to exploit remarkable developments in digital imaging, nanoparticle multiplex staining, and computational image analysis software to bridge the traditional histology - global “–omic” analyses gap. Included are side-by-side comparisons, objective biopsy finding quantification, multiplexing, automated image analysis, and electronic data and resource sharing. Current utilization for teaching, quality assurance, conferencing, consultations, research and clinical trials is evolving toward implementation for low-volume, high-complexity clinical services like transplantation pathology. Cost, complexities of implementation, fluid/evolving standards, and unsettled medical/legal and regulatory issues remain as challenges. Regardless, challenges will be overcome and these technologies will enable transplant pathologists to increase information extraction from tissue specimens and contribute to cross-platform biomarker discovery for improved outcomes. PMID:22053785

New concept high-speed and high-resolution color scanner

NASA Astrophysics Data System (ADS)

Nakashima, Keisuke; Shinoda, Shin'ichi; Konishi, Yoshiharu; Sugiyama, Kenji; Hori, Tetsuya

2003-05-01

We have developed a new concept high-speed and high-resolution color scanner (Blinkscan) using digital camera technology. With our most advanced sub-pixel image processing technology, approximately 12 million pixel image data can be captured. High resolution imaging capability allows various uses such as OCR, color document read, and document camera. The scan time is only about 3 seconds for a letter size sheet. Blinkscan scans documents placed "face up" on its scan stage and without any special illumination lights. Using Blinkscan, a high-resolution color document can be easily inputted into a PC at high speed, a paperless system can be built easily. It is small, and since the occupancy area is also small, setting it on an individual desk is possible. Blinkscan offers the usability of a digital camera and accuracy of a flatbed scanner with high-speed processing. Now, about several hundred of Blinkscan are mainly shipping for the receptionist operation in a bank and a security. We will show the high-speed and high-resolution architecture of Blinkscan. Comparing operation-time with conventional image capture device, the advantage of Blinkscan will make clear. And image evaluation for variety of environment, such as geometric distortions or non-uniformity of brightness, will be made.

42 CFR 37.51 - Interpreting and classifying chest radiographs-digital radiography systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... standard digital chest radiographic images provided for use with the Guidelines for the Use of the ILO... NIOSH-approved standard digital images may be used for classifying digital chest images for pneumoconiosis. Modification of the appearance of the standard images using software tools is not permitted. (d...

The CAOS camera platform: ushering in a paradigm change in extreme dynamic range imager design

NASA Astrophysics Data System (ADS)

Riza, Nabeel A.

2017-02-01

Multi-pixel imaging devices such as CCD, CMOS and Focal Plane Array (FPA) photo-sensors dominate the imaging world. These Photo-Detector Array (PDA) devices certainly have their merits including increasingly high pixel counts and shrinking pixel sizes, nevertheless, they are also being hampered by limitations in instantaneous dynamic range, inter-pixel crosstalk, quantum full well capacity, signal-to-noise ratio, sensitivity, spectral flexibility, and in some cases, imager response time. Recently invented is the Coded Access Optical Sensor (CAOS) Camera platform that works in unison with current Photo-Detector Array (PDA) technology to counter fundamental limitations of PDA-based imagers while providing high enough imaging spatial resolution and pixel counts. Using for example the Texas Instruments (TI) Digital Micromirror Device (DMD) to engineer the CAOS camera platform, ushered in is a paradigm change in advanced imager design, particularly for extreme dynamic range applications.

Cardiac Imaging System

NASA Technical Reports Server (NTRS)

1990-01-01

Although not available to all patients with narrowed arteries, balloon angioplasty has expanded dramatically since its introduction with an estimated further growth to 562,000 procedures in the U.S. alone by 1992. Growth has fueled demand for higher quality imaging systems that allow the cardiologist to be more accurate and increase the chances of a successful procedure. A major advance is the Digital Cardiac Imaging (DCI) System designed by Philips Medical Systems International, Best, The Netherlands and marketed in the U.S. by Philips Medical Systems North America Company. The key benefit is significantly improved real-time imaging and the ability to employ image enhancement techniques to bring out added details. Using a cordless control unit, the cardiologist can manipulate images to make immediate assessment, compare live x-ray and roadmap images by placing them side-by-side on monitor screens, or compare pre-procedure and post procedure conditions. The Philips DCI improves the cardiologist's precision by expanding the information available to him.

Advanced Exploration Technologies: Micro and Nano Technologies Enabling Space Missions in the 21st Century

NASA Technical Reports Server (NTRS)

Krabach, Timothy

1998-01-01

Some of the many new and advanced exploration technologies which will enable space missions in the 21st century and specifically the Manned Mars Mission are explored in this presentation. Some of these are the system on a chip, the Computed-Tomography imaging Spectrometer, the digital camera on a chip, and other Micro Electro Mechanical Systems (MEMS) technology for space. Some of these MEMS are the silicon micromachined microgyroscope, a subliming solid micro-thruster, a micro-ion thruster, a silicon seismometer, a dewpoint microhygrometer, a micro laser doppler anemometer, and tunable diode laser (TDL) sensors. The advanced technology insertion is critical for NASA to decrease mass, volume, power and mission costs, and increase functionality, science potential and robustness.

[Comparative evaluation of six different body regions of the dog using analog and digital radiography].

PubMed

Meyer-Lindenberg, Andrea; Ebermaier, Christine; Wolvekamp, Pim; Tellhelm, Bernd; Meutstege, Freek J; Lang, Johann; Hartung, Klaus; Fehr, Michael; Nolte, Ingo

2008-01-01

In this study the quality of digital and analog radiography in dogs was compared. For this purpose, three conventional radiographs (varying in exposure) and three digital radiographs (varying in MUSI-contrast [MUSI = MUlti Scale Image Contrast], the main post-processing parameter) of six different body regions of the dog were evaluated (thorax, abdomen, skull, femur, hip joints, elbow). The quality of the radiographs was evaluated by eight veterinary specialists familiar with radiographic images using a questionnaire based on details of each body region significant in obtaining a radiographic diagnosis. In the first part of the study the overall quality of the radiographs was evaluated. Within one region, 89.5% (43/48) chose a digital radiograph as the best image. Divided into analog and digital groups, the digital image with the highest MUSI-contrast was most often considered the best, while the analog image considered the best varied between the one with the medium and the one with the longest exposure time. In the second part of the study, each image was rated for the visibility of specific, diagnostically important details. After summarisation of the scores for each criterion, divided into analog and digital imaging, the digital images were rated considerably superior to conventional images. The results of image comparison revealed that digital radiographs showed better image detail than radiographs taken with the analog technique in all six areas of the body.

Confocal mosaicing microscopy of human skin ex vivo: spectral analysis for digital staining to simulate histology-like appearance

NASA Astrophysics Data System (ADS)

Bini, Jason; Spain, James; Nehal, Kishwer; Hazelwood, Vikki; Dimarzio, Charles; Rajadhyaksha, Milind

2011-07-01

Confocal mosaicing microscopy enables rapid imaging of large areas of fresh tissue, without the processing that is necessary for conventional histology. Mosaicing may offer a means to perform rapid histology at the bedside. A possible barrier toward clinical acceptance is that the mosaics are based on a single mode of grayscale contrast and appear black and white, whereas histology is based on two stains (hematoxylin for nuclei, eosin for cellular cytoplasm and dermis) and appears purple and pink. Toward addressing this barrier, we report advances in digital staining: fluorescence mosaics that show only nuclei, are digitally stained purple and overlaid on reflectance mosaics, which show only cellular cytoplasm and dermis, and are digitally stained pink. With digital staining, the appearance of confocal mosaics mimics the appearance of histology. Using multispectral analysis and color matching functions, red, green, and blue (RGB) components of hematoxylin and eosin stains in tissue were determined. The resulting RGB components were then applied in a linear algorithm to transform fluorescence and reflectance contrast in confocal mosaics to the absorbance contrast seen in pathology. Optimization of staining with acridine orange showed improved quality of digitally stained mosaics, with good correlation to the corresponding histology.

Digital mammography, cancer screening: Factors important for image compression

NASA Technical Reports Server (NTRS)

Clarke, Laurence P.; Blaine, G. James; Doi, Kunio; Yaffe, Martin J.; Shtern, Faina; Brown, G. Stephen; Winfield, Daniel L.; Kallergi, Maria

1993-01-01

The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression algorithms for image storage, transmission, and remote diagnosis. X-ray digital mammography using novel direct digital detection schemes or film digitizers results in large data sets and, therefore, image compression methods will play a significant role in the image processing and analysis by CAD techniques. In view of the extensive compression required, the relative merit of 'virtually lossless' versus lossy methods should be determined. A brief overview is presented here of the developments of digital sensors, CAD, and compression methods currently proposed and tested for mammography. The objective of the NCI/NASA Working Group on Digital Mammography is to stimulate the interest of the image processing and compression scientific community for this medical application and identify possible dual use technologies within the NASA centers.

Radiologists' preferences for digital mammographic display. The International Digital Mammography Development Group.

PubMed

Pisano, E D; Cole, E B; Major, S; Zong, S; Hemminger, B M; Muller, K E; Johnston, R E; Walsh, R; Conant, E; Fajardo, L L; Feig, S A; Nishikawa, R M; Yaffe, M J; Williams, M B; Aylward, S R

2000-09-01

To determine the preferences of radiologists among eight different image processing algorithms applied to digital mammograms obtained for screening and diagnostic imaging tasks. Twenty-eight images representing histologically proved masses or calcifications were obtained by using three clinically available digital mammographic units. Images were processed and printed on film by using manual intensity windowing, histogram-based intensity windowing, mixture model intensity windowing, peripheral equalization, multiscale image contrast amplification (MUSICA), contrast-limited adaptive histogram equalization, Trex processing, and unsharp masking. Twelve radiologists compared the processed digital images with screen-film mammograms obtained in the same patient for breast cancer screening and breast lesion diagnosis. For the screening task, screen-film mammograms were preferred to all digital presentations, but the acceptability of images processed with Trex and MUSICA algorithms were not significantly different. All printed digital images were preferred to screen-film radiographs in the diagnosis of masses; mammograms processed with unsharp masking were significantly preferred. For the diagnosis of calcifications, no processed digital mammogram was preferred to screen-film mammograms. When digital mammograms were preferred to screen-film mammograms, radiologists selected different digital processing algorithms for each of three mammographic reading tasks and for different lesion types. Soft-copy display will eventually allow radiologists to select among these options more easily.

Computer-aided detection (CAD) of breast cancer on full field digital and screening film mammograms

NASA Astrophysics Data System (ADS)

Sun, Xuejun; Qian, Wei; Song, Xiaoshan; Qian, Yuyan; Song, Dansheng; Clark, Robert A.

2003-05-01

Full-field digital mammography (FFDM) as a new breast imaging modality has potential to detect more breast cancers or to detect them at smaller sizes and earlier stages compared with screening film mammography (SFM). However, its performance needs verification, and it would pose new problems for the development of CAD methods for breast cancer detection and diagnosis. Performance evaluation of CAD systems on FFDM and SFM has been conducted in this study, respectively. First, an adaptive CAD system employing a series of advanced modules has been developed on FFDM. Second, a standardization approach has been developed to make the CAD system independent of characteristics of digitizer or imaging modalities for mammography. CAD systems developed previously for SFM and developed in this study for FFDM have been evaluated on FFDM and SFM images without and with standardization, respectively, to examine the performance improvement of the CAD system developed in this study. Computerized free-response receiver operating characteristic (FROC) analysis has been adopted as performance evaluation method. Compared with previous one, the CAD system developed in this study demonstrated significantly performance improvements. However, the comparison results have shown that the performances of final CAD system in this study are not significantly different on FFDM and on SFM after standardization. It needs further study on the assessment of CAD system performance on FFDM and SFM modalities.

Lumbar spine radiography — poor collimation practices after implementation of digital technology

PubMed Central

Zetterberg, L G; Espeland, A

2011-01-01

Objectives The transition from analogue to digital radiography may have reduced the motivation to perform proper collimation, as digital techniques have made it possible to mask areas irradiated outside the area of diagnostic interest (ADI). We examined the hypothesis that collimation practices have deteriorated since digitalisation. Methods After defining the ADI, we compared the proportion of the irradiated field outside the ADI in 86 digital and 86 analogue frontal lumbar spine radiographs using the Mann–Whitney test. 50 digital images and 50 analogue images were from a Norwegian hospital and the remainder from a Danish hospital. Consecutive digital images were compared with analogue images (from the hospitals' archives) produced in the 4 years prior to digitalisation. Both hospitals' standard radiographic procedures remained unchanged during the study. For digital images, the irradiated field was assessed using non-masked raw-data images. Results The proportion of the irradiated field outside the ADI was larger in digital than in analogue images (mean 61.7% vs 42.4%, p<0.001), and also in a subsample of 39 image pairs that could be matched for patient age (p<0.001). The mean total field size was 46% larger in digital than in analogue images (791 cm2 vs 541 cm2). Conclusion Following the implementation of digital radiography, considerably larger areas were irradiated. This causes unnecessarily high radiation doses to patients. PMID:21606070

Digital Image Analysis System for Monitoring Crack Growth at Elevated Temperature

DTIC Science & Technology

1988-05-01

The objective of the research work reported here was to develop a new concept, based on Digital Image Analysis , for monitoring the crack-tip position...a 512 x 512 pixel frame. c) Digital Image Analysis software developed to locate and digitize the position of the crack-tip, on the observed image

[Improvement of Digital Capsule Endoscopy System and Image Interpolation].

PubMed

Zhao, Shaopeng; Yan, Guozheng; Liu, Gang; Kuang, Shuai

2016-01-01

Traditional capsule image collects and transmits analog image, with weak anti-interference ability, low frame rate, low resolution. This paper presents a new digital image capsule, which collects and transmits digital image, with frame rate up to 30 frames/sec and pixels resolution of 400 x 400. The image is compressed in the capsule, and is transmitted to the outside of the capsule for decompression and interpolation. A new type of interpolation algorithm is proposed, which is based on the relationship between the image planes, to obtain higher quality colour images. capsule endoscopy, digital image, SCCB protocol, image interpolation

A model for a PC-based, universal-format, multimedia digitization system: moving beyond the scanner.

PubMed

McEachen, James C; Cusack, Thomas J; McEachen, John C

2003-08-01

Digitizing images for use in case presentations based on hardcopy films, slides, photographs, negatives, books, and videos can present a challenging task. Scanners and digital cameras have become standard tools of the trade. Unfortunately, use of these devices to digitize multiple images in many different media formats can be a time-consuming and in some cases unachievable process. The authors' goal was to create a PC-based solution for digitizing multiple media formats in a timely fashion while maintaining adequate image presentation quality. The authors' PC-based solution makes use of off-the-shelf hardware applications to include a digital document camera (DDC), VHS video player, and video-editing kit. With the assistance of five staff radiologists, the authors examined the quality of multiple image types digitized with this equipment. The authors also quantified the speed of digitization of various types of media using the DDC and video-editing kit. With regard to image quality, the five staff radiologists rated the digitized angiography, CT, and MR images as adequate to excellent for use in teaching files and case presentations. With regard to digitized plain films, the average rating was adequate. As for performance, the authors recognized a 68% improvement in the time required to digitize hardcopy films using the DDC instead of a professional quality scanner. The PC-based solution provides a means for digitizing multiple images from many different types of media in a timely fashion while maintaining adequate image presentation quality.

Combat vehicle crew helmet-mounted display: next generation high-resolution head-mounted display

NASA Astrophysics Data System (ADS)

Nelson, Scott A.

1994-06-01

The Combat Vehicle Crew Head-Mounted Display (CVC HMD) program is an ARPA-funded, US Army Natick Research, Development, and Engineering Center monitored effort to develop a high resolution, flat panel HMD for the M1 A2 Abrams main battle tank. CVC HMD is part of the ARPA High Definition Systems (HDS) thrust to develop and integrate small (24 micrometers square pels), high resolution (1280 X 1024 X 6-bit grey scale at 60 frame/sec) active matrix electroluminescent (AMEL) and active matrix liquid crystal displays (AMLCD) for head mounted and projection applications. The Honeywell designed CVC HMD is a next generation head-mounted display system that includes advanced flat panel image sources, advanced digital display driver electronics, high speed (> 1 Gbps) digital interconnect electronics, and light weight, high performance optical and mechanical designs. The resulting dramatic improvements in size, weight, power, and cost have already led to program spin offs for both military and commercial applications.

High performance 3D adaptive filtering for DSP based portable medical imaging systems

NASA Astrophysics Data System (ADS)

Bockenbach, Olivier; Ali, Murtaza; Wainwright, Ian; Nadeski, Mark

2015-03-01

Portable medical imaging devices have proven valuable for emergency medical services both in the field and hospital environments and are becoming more prevalent in clinical settings where the use of larger imaging machines is impractical. Despite their constraints on power, size and cost, portable imaging devices must still deliver high quality images. 3D adaptive filtering is one of the most advanced techniques aimed at noise reduction and feature enhancement, but is computationally very demanding and hence often cannot be run with sufficient performance on a portable platform. In recent years, advanced multicore digital signal processors (DSP) have been developed that attain high processing performance while maintaining low levels of power dissipation. These processors enable the implementation of complex algorithms on a portable platform. In this study, the performance of a 3D adaptive filtering algorithm on a DSP is investigated. The performance is assessed by filtering a volume of size 512x256x128 voxels sampled at a pace of 10 MVoxels/sec with an Ultrasound 3D probe. Relative performance and power is addressed between a reference PC (Quad Core CPU) and a TMS320C6678 DSP from Texas Instruments.

e-phenology: monitoring leaf phenology and tracking climate changes in the tropics

NASA Astrophysics Data System (ADS)

Morellato, Patrícia; Alberton, Bruna; Almeida, Jurandy; Alex, Jefersson; Mariano, Greice; Torres, Ricardo

2014-05-01

The e-phenology is a multidisciplinary project combining research in Computer Science and Phenology. Its goal is to attack theoretical and practical problems involving the use of new technologies for remote phenological observation aiming to detect local environmental changes. It is geared towards three objectives: (a) the use of new technologies of environmental monitoring based on remote phenology monitoring systems; (b) creation of a protocol for a Brazilian long term phenology monitoring program and for the integration across disciplines, advancing our knowledge of seasonal responses within tropics to climate change; and (c) provide models, methods and algorithms to support management, integration and analysis of data of remote phenology systems. The research team is composed by computer scientists and biology researchers in Phenology. Our first results include: Phenology towers - We set up the first phenology tower in our core cerrado-savanna 1 study site at Itirapina, São Paulo, Brazil. The tower received a complete climatic station and a digital camera. The digital camera is set up to take daily sequence of images (five images per hour, from 6:00 to 18:00 h). We set up similar phenology towers with climatic station and cameras in five more sites: cerrado-savanna 2 (Pé de Gigante, SP), cerrado grassland 3 (Itirapina, SP), rupestrian fields 4 ( Serra do Cipo, MG), seasonal forest 5 (Angatuba, SP) and Atlantic raiforest 6 (Santa Virginia, SP). Phenology database - We finished modeling and validation of a phenology database that stores ground phenology and near-remote phenology, and we are carrying out the implementation with data ingestion. Remote phenology and image processing - We performed the first analyses of the cerrado sites 1 to 4 phenology derived from digital images. Analysis were conducted by extracting color information (RGB Red, Green and Blue color channels) from selected parts of the image named regions of interest (ROI). using the green color channel. We analyzed a daily sequence of images (6:00 to 18:00 h). Our results are innovative and indicate the great variation in color change response for tropical trees. We validate the camera phenology with our on the ground direct observation in the core cerrado site 1. We are developing a Image processing software to authomatic process the digital images and to generate the time series for further analyses. New techniques and image features have been used to extract seasonal features from data and for data processing, such as machine learning and visual rhythms. Machine learning was successful applied to identify similar species within the image. Visual rhythms show up as a new analytic tool for phenological interpretation. Next research steps include the analyses of longer data series, correlation with local climatic data, analyses and comparison of patterns among different vegetation sites, prepare a compressive protocol for digital camera phenology and develop new technologies to access vegetation changes using digital cameras. Support: FAPESP-Micorsoft Research, CNPq, CAPES.

Pre-Hardware Optimization and Implementation Of Fast Optics Closed Control Loop Algorithms

NASA Technical Reports Server (NTRS)

Kizhner, Semion; Lyon, Richard G.; Herman, Jay R.; Abuhassan, Nader

2004-01-01

One of the main heritage tools used in scientific and engineering data spectrum analysis is the Fourier Integral Transform and its high performance digital equivalent - the Fast Fourier Transform (FFT). The FFT is particularly useful in two-dimensional (2-D) image processing (FFT2) within optical systems control. However, timing constraints of a fast optics closed control loop would require a supercomputer to run the software implementation of the FFT2 and its inverse, as well as other image processing representative algorithm, such as numerical image folding and fringe feature extraction. A laboratory supercomputer is not always available even for ground operations and is not feasible for a night project. However, the computationally intensive algorithms still warrant alternative implementation using reconfigurable computing technologies (RC) such as Digital Signal Processors (DSP) and Field Programmable Gate Arrays (FPGA), which provide low cost compact super-computing capabilities. We present a new RC hardware implementation and utilization architecture that significantly reduces the computational complexity of a few basic image-processing algorithm, such as FFT2, image folding and phase diversity for the NASA Solar Viewing Interferometer Prototype (SVIP) using a cluster of DSPs and FPGAs. The DSP cluster utilization architecture also assures avoidance of a single point of failure, while using commercially available hardware. This, combined with the control algorithms pre-hardware optimization, or the first time allows construction of image-based 800 Hertz (Hz) optics closed control loops on-board a spacecraft, based on the SVIP ground instrument. That spacecraft is the proposed Earth Atmosphere Solar Occultation Imager (EASI) to study greenhouse gases CO2, C2H, H2O, O3, O2, N2O from Lagrange-2 point in space. This paper provides an advanced insight into a new type of science capabilities for future space exploration missions based on on-board image processing for control and for robotics missions using vision sensors. It presents a top-level description of technologies required for the design and construction of SVIP and EASI and to advance the spatial-spectral imaging and large-scale space interferometry science and engineering.

Patient-generated Digital Images after Pediatric Ambulatory Surgery.

PubMed

Miller, Matthew W; Ross, Rachael K; Voight, Christina; Brouwer, Heather; Karavite, Dean J; Gerber, Jeffrey S; Grundmeier, Robert W; Coffin, Susan E

2016-07-06

To describe the use of digital images captured by parents or guardians and sent to clinicians for assessment of wounds after pediatric ambulatory surgery. Subjects with digital images of post-operative wounds were identified as part of an on-going cohort study of infections after ambulatory surgery within a large pediatric healthcare system. We performed a structured review of the electronic health record (EHR) to determine how digital images were documented in the EHR and used in clinical care. We identified 166 patients whose parent or guardian reported sending a digital image of the wound to the clinician after surgery. A corresponding digital image was located in the EHR in only 121 of these encounters. A change in clinical management was documented in 20% of these encounters, including referral for in-person evaluation of the wound and antibiotic prescription. Clinical teams have developed ad hoc workflows to use digital images to evaluate post-operative pediatric surgical patients. Because the use of digital images to support follow-up care after ambulatory surgery is likely to increase, it is important that high-quality images are captured and documented appropriately in the EHR to ensure privacy, security, and a high-level of care.

Patient-Generated Digital Images after Pediatric Ambulatory Surgery

PubMed Central

Ross, Rachael K.; Voight, Christina; Brouwer, Heather; Karavite, Dean J.; Gerber, Jeffrey S.; Grundmeier, Robert W.; Coffin, Susan E.

2016-01-01

Summary Objective To describe the use of digital images captured by parents or guardians and sent to clinicians for assessment of wounds after pediatric ambulatory surgery. Methods Subjects with digital images of post-operative wounds were identified as part of an ongoing cohort study of infections after ambulatory surgery within a large pediatric healthcare system. We performed a structured review of the electronic health record (EHR) to determine how digital images were documented in the EHR and used in clinical care. Results We identified 166 patients whose parent or guardian reported sending a digital image of the wound to the clinician after surgery. A corresponding digital image was located in the EHR in only 121 of these encounters. A change in clinical management was documented in 20% of these encounters, including referral for in-person evaluation of the wound and antibiotic prescription. Conclusion Clinical teams have developed ad hoc workflows to use digital images to evaluate post-operative pediatric surgical patients. Because the use of digital images to support follow-up care after ambulatory surgery is likely to increase, it is important that high-quality images are captured and documented appropriately in the EHR to ensure privacy, security, and a high-level of care. PMID:27452477

Characterization of ASTER GDEM Elevation Data over Vegetated Area Compared with Lidar Data

NASA Technical Reports Server (NTRS)

Ni, Wenjian; Sun, Guoqing; Ranson, Kenneth J.

2013-01-01

Current researches based on areal or spaceborne stereo images with very high resolutions (less than 1 meter) have demonstrated that it is possible to derive vegetation height from stereo images. The second version of the Advanced Spaceborne Thermal Emission and Reflection Radiometer Global Digital Elevation Model (ASTER GDEM) is a state-of-the-art global elevation data-set developed by stereo images. However, the resolution of ASTER stereo images (15 meters) is much coarser than areal stereo images, and the ASTER GDEM is compiled products from stereo images acquired over 10 years. The forest disturbances as well as forest growth are inevitable in 10 years time span. In this study, the features of ASTER GDEM over vegetated areas under both flat and mountainous conditions were investigated by comparisons with lidar data. The factors possibly affecting the extraction of vegetation canopy height considered include (1) co-registration of DEMs; (2) spatial resolution of digital elevation models (DEMs); (3) spatial vegetation structure; and (4) terrain slope. The results show that accurate co-registration between ASTER GDEM and the National Elevation Dataset (NED) is necessary over mountainous areas. The correlation between ASTER GDEM minus NED and vegetation canopy height is improved from 0.328 to 0.43 by degrading resolutions from 1 arc-second to 5 arc-seconds and further improved to 0.6 if only homogenous vegetated areas were considered.

The effects of gray scale image processing on digital mammography interpretation performance.

PubMed

Cole, Elodia B; Pisano, Etta D; Zeng, Donglin; Muller, Keith; Aylward, Stephen R; Park, Sungwook; Kuzmiak, Cherie; Koomen, Marcia; Pavic, Dag; Walsh, Ruth; Baker, Jay; Gimenez, Edgardo I; Freimanis, Rita

2005-05-01

To determine the effects of three image-processing algorithms on diagnostic accuracy of digital mammography in comparison with conventional screen-film mammography. A total of 201 cases consisting of nonprocessed soft copy versions of the digital mammograms acquired from GE, Fischer, and Trex digital mammography systems (1997-1999) and conventional screen-film mammograms of the same patients were interpreted by nine radiologists. The raw digital data were processed with each of three different image-processing algorithms creating three presentations-manufacturer's default (applied and laser printed to film by each of the manufacturers), MUSICA, and PLAHE-were presented in soft copy display. There were three radiologists per presentation. Area under the receiver operating characteristic curve for GE digital mass cases was worse than screen-film for all digital presentations. The area under the receiver operating characteristic for Trex digital mass cases was better, but only with images processed with the manufacturer's default algorithm. Sensitivity for GE digital mass cases was worse than screen film for all digital presentations. Specificity for Fischer digital calcifications cases was worse than screen film for images processed in default and PLAHE algorithms. Specificity for Trex digital calcifications cases was worse than screen film for images processed with MUSICA. Specific image-processing algorithms may be necessary for optimal presentation for interpretation based on machine and lesion type.

Transfer of Technology for Cadastral Mapping in Tajikistan Using High Resolution Satellite Data

NASA Astrophysics Data System (ADS)

Kaczynski, R.

2012-07-01

European Commission funded project entitled: "Support to the mapping and certification capacity of the Agency of Land Management, Geodesy and Cartography" in Tajikistan was run by FINNMAP FM-International and Human Dynamics from Nov. 2006 to June 2011. The Agency of Land Management, Geodesy and Cartography is the state agency responsible for development, implementation, monitoring and evaluation of state policies on land tenure and land management, including the on-going land reform and registration of land use rights. The specific objective was to support and strengthen the professional capacity of the "Fazo" Institute in the field of satellite geodesy, digital photogrammetry, advanced digital satellite image processing of high resolution satellite data and digital cartography. Lectures and on-the-job trainings for the personnel of "Fazo" and Agency in satellite geodesy, digital photogrammetry, cartography and the use of high resolution satellite data for cadastral mapping have been organized. Standards and Quality control system for all data and products have been elaborated and implemented in the production line. Technical expertise and trainings in geodesy, photogrammetry and satellite image processing to the World Bank project "Land Registration and Cadastre System for Sustainable Agriculture" has also been completed in Tajikistan. The new map projection was chosen and the new unclassified geodetic network has been established for all of the country in which all agricultural parcel boundaries are being mapped. IKONOS, QuickBird and WorldView1 panchromatic data have been used for orthophoto generation. Average accuracy of space triangulation of non-standard (long up to 90km) satellite images of QuickBird Pan and IKONOS Pan on ICPs: RMSEx = 0.5m and RMSEy = 0.5m have been achieved. Accuracy of digital orthophoto map is RMSExy = 1.0m. More then two and half thousands of digital orthophoto map sheets in the scale of 1:5000 with pixel size 0.5m have been produced so far by the "Fazo" Institute in Tajikistan on the basis of technology elaborated in the framework of this project. Digital cadastral maps are produced in "Fazo" and Cadastral Regional Centers in Tajikistan using ArcMap software. These digital orthophotomaps will also be used for digital mapping of water resources and other needs of the country.

One hundred case studies of Asia-Pacific telemedicine using a digital video transport system over a research and education network.

PubMed

Shimizu, Shuji; Nakashima, Naoki; Okamura, Koji; Tanaka, Masao

2009-01-01

Although the use of video in telemedicine is most helpful, the transmission of high-quality moving images is difficult in conventional systems due to the limitation of network bandwidth and the quality of service. We have established a new system via the academic broadband network that can preserve the original quality and assure smooth movement of the image. Here we report on 100 case studies and discuss the lessons we have learned. Kyushu University Hospital in Fukuoka, Japan, was linked to 53 medical institutions and meeting venues in 13 countries and regions over the Asia-Pacific Advanced Network, an international research and education consortium. The digital video transport system (DVTS), free software that transforms digital video signals directly into Internet Protocol, was installed on a personal computer (PC) with a network bandwidth of 30 Mbps per channel. Between February 2003 and June 2007, 100 telecommunication sessions were held, 94 of which were international and 6 domestic. Furthermore, 47 involved real-time demonstrations and 53 interactive teleconferences using video or PC presentations. Multiple stations were connected in 37 events, and the number of connected stations in total reached 269. The time delay was restricted to 0.3-1.0 seconds between the stations. Participants provided feedback via questionnaires, and with respect to image quality, 509 (68.3%) participants reported "very good," 206 (27.7%) reported "good," 19 (2.6%) reported "poor," and 11 (1.5%) reported "very poor." DVTS is both economical, with a minimal initial investment, and simple to set up, and this is the first time that this advanced system has been used so widely in the Asia-Pacific region. Because the high-speed academic network for research and education is available worldwide, we believe our cutting-edge technology will facilitate medical standardization beyond geographic borders in the world.

Interpretation and mapping of geological features using mobile devices for 3D outcrop modelling

NASA Astrophysics Data System (ADS)

Buckley, Simon J.; Kehl, Christian; Mullins, James R.; Howell, John A.

2016-04-01

Advances in 3D digital geometric characterisation have resulted in widespread adoption in recent years, with photorealistic models utilised for interpretation, quantitative and qualitative analysis, as well as education, in an increasingly diverse range of geoscience applications. Topographic models created using lidar and photogrammetry, optionally combined with imagery from sensors such as hyperspectral and thermal cameras, are now becoming commonplace in geoscientific research. Mobile devices (tablets and smartphones) are maturing rapidly to become powerful field computers capable of displaying and interpreting 3D models directly in the field. With increasingly high-quality digital image capture, combined with on-board sensor pose estimation, mobile devices are, in addition, a source of primary data, which can be employed to enhance existing geological models. Adding supplementary image textures and 2D annotations to photorealistic models is therefore a desirable next step to complement conventional field geoscience. This contribution reports on research into field-based interpretation and conceptual sketching on images and photorealistic models on mobile devices, motivated by the desire to utilise digital outcrop models to generate high quality training images (TIs) for multipoint statistics (MPS) property modelling. Representative training images define sedimentological concepts and spatial relationships between elements in the system, which are subsequently modelled using artificial learning to populate geocellular models. Photorealistic outcrop models are underused sources of quantitative and qualitative information for generating TIs, explored further in this research by linking field and office workflows through the mobile device. Existing textured models are loaded to the mobile device, allowing rendering in a 3D environment. Because interpretation in 2D is more familiar and comfortable for users, the developed application allows new images to be captured with the device's digital camera, and an interface is available for annotating (interpreting) the image using lines and polygons. Image-to-geometry registration is then performed using a developed algorithm, initialised using the coarse pose from the on-board orientation and positioning sensors. The annotations made on the captured images are then available in the 3D model coordinate system for overlay and export. This workflow allows geologists to make interpretations and conceptual models in the field, which can then be linked to and refined in office workflows for later MPS property modelling.

Functional imaging of glucose-evoked rat islet activities using transient intrinsic optical signals

NASA Astrophysics Data System (ADS)

Yao, Xin-Cheng; Cui, Wan-Xing; Li, Yi-Chao; Zhang, Wei; Lu, Rong-Wen; Thompson, Anthony; Amthor, Franklin; Wang, Xu-Jing

2012-05-01

We demonstrate intrinsic optical signal (IOS) imaging of intact rat islet, which consists of many endocrine cells working together. A near-infrared digital microscope was employed for optical monitoring of islet activities evoked by glucose stimulation. Dynamic NIR images revealed transient IOS responses in the islet activated by low-dose (2.75 mM) and high-dose (5.5 mM) glucose stimuli. Comparative experiments and quantitative analysis indicated that both glucose metabolism and calcium/insulin dynamics might contribute to the observed IOS responses. Further investigation of the IOS imaging technology may provide a high resolution method for ex vivo functional examination of the islet, which is important for advanced study of diabetes associated islet dysfunctions and for improved quality control of donor islets for transplantation.

High-resolution streaming video integrated with UGS systems

NASA Astrophysics Data System (ADS)

Rohrer, Matthew

2010-04-01

Imagery has proven to be a valuable complement to Unattended Ground Sensor (UGS) systems. It provides ultimate verification of the nature of detected targets. However, due to the power, bandwidth, and technological limitations inherent to UGS, sacrifices have been made to the imagery portion of such systems. The result is that these systems produce lower resolution images in small quantities. Currently, a high resolution, wireless imaging system is being developed to bring megapixel, streaming video to remote locations to operate in concert with UGS. This paper will provide an overview of how using Wifi radios, new image based Digital Signal Processors (DSP) running advanced target detection algorithms, and high resolution cameras gives the user an opportunity to take high-powered video imagers to areas where power conservation is a necessity.

VHDL Modeling and Simulation of a Digital Image Synthesizer for Countering ISAR

DTIC Science & Technology

2003-06-01

This thesis discusses VHDL modeling and simulation of a full custom Application Specific Integrated Circuit (ASIC) for a Digital Image Synthesizer...necessary for a given application . With such a digital method, it is possible for a small ship to appear as large as an aircraft carrier or any high...INTRODUCTION TO DIGITAL IMAGE SYNTHESIZER (DIS) A. BACKGROUND The Digital Image Synthesizer (DIS) is an Application Specific Integrated Circuit

21 CFR 892.1715 - Full-field digital mammography system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... planar digital x-ray images of the entire breast. This generic type of device may include digital mammography acquisition software, full-field digital image receptor, acquisition workstation, automatic exposure control, image processing and reconstruction programs, patient and equipment supports, component...

21 CFR 892.1715 - Full-field digital mammography system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... planar digital x-ray images of the entire breast. This generic type of device may include digital mammography acquisition software, full-field digital image receptor, acquisition workstation, automatic exposure control, image processing and reconstruction programs, patient and equipment supports, component...

21 CFR 892.1715 - Full-field digital mammography system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... planar digital x-ray images of the entire breast. This generic type of device may include digital mammography acquisition software, full-field digital image receptor, acquisition workstation, automatic exposure control, image processing and reconstruction programs, patient and equipment supports, component...

21 CFR 892.1715 - Full-field digital mammography system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... planar digital x-ray images of the entire breast. This generic type of device may include digital mammography acquisition software, full-field digital image receptor, acquisition workstation, automatic exposure control, image processing and reconstruction programs, patient and equipment supports, component...

Staging of breast cancer and the advanced applications of digital mammogram: what the physician needs to know?

PubMed

Helal, Maha H; Mansour, Sahar M; Zaglol, Mai; Salaleldin, Lamia A; Nada, Omniya M; Haggag, Marwa A

2017-03-01

To study the role of advanced applications of digital mammogram, whether contrast-enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT), in the "T" staging of histologically proven breast cancer before planning for treatment management. In this prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and the presence of associated clusters of microcalcifications. Evaluation methods included digital mammography (DM), 3D tomosynthesis and CESM. Traditional DM was first performed then in a period of 10-14-day interval; breast tomosynthesis and contrast-based mammography were performed for the involved breast only. Views at tomosynthesis were acquired in a "step-and-shoot" tube motion mode to produce multiple (11-15), low-dose images and in contrast-enhanced study, low-energy (22-33 kVp) and high-energy (44-49 kVp) exposures were taken after the i.v. injection of the contrast agent. Operative data were the gold standard reference. Breast tomosynthesis showed the highest accuracy in size assessment (n = 69, 70.4%) than contrast-enhanced (n = 49, 50%) and regular mammography (n = 59, 60.2%). Contrast-enhanced mammography presented the least performance in assessing calcifications, yet it was most sensitive in the detection of multiplicity (92.3%), followed by tomosynthesis (77%) and regular mammography (53.8%). The combined analysis of the three modalities provided an accuracy of 74% in the "T" staging of breast cancer. The combined application of tomosynthesis and contrast-enhanced digital mammogram enhanced the performance of the traditional DM and presented an informative method in the staging of breast cancer. Advances in knowledge: Staging and management planning of breast cancer can divert according to tumour size, multiplicity and the presence of microcalcifications. DBT shows sharp outlines of the tumour with no overlap tissue and spots microcalcifications. Contrast-enhanced spectral mammogram shows the extent of abnormal contrast uptake and detects multiplicity. Integrated analysis provides optimal findings for proper "T" staging of breast cancer.

Integrated Digital Platform for the Valorization of a Cultural Landscape

NASA Astrophysics Data System (ADS)

Angheluţǎ, L. M.; Ratoiu, L.; Chelmus, A. I.; Rǎdvan, R.; Petculescu, A.

2017-05-01

This paper presents a newly started demonstrative project regarding the implementation and validation of an interdisciplinary research model for the Aluniş-Bozioru (Romania) cultural landscape, with the development of an online interactive digital product. This digital product would provide complementary data about the historical monuments and their environment, and also, constant updates and statistical comparison in order to generate an accurate evaluation of the state of conservation for this specific cultural landscape. Furthermore, the resulted information will contribute in the decision making process for the regional development policies. The project is developed by an interdisciplinary joint team of researchers consisted of technical scientists with great experience in advanced non-invasive characterization of the cultural heritage (NIRD for Optoelectronics - INOE 2000) and a group of experts from geology and biology (Romanian Academy's "Emil Racoviţǎ" Institute of Speleology - ISER). Resulted scientific data will include: 3D digital models of the selected historical monuments, microclimate monitoring, Ground Penetrating Radar survey, airborne LIDAR, multispectral and thermal imaging, soil and rock characterization, environmental studies. This digital product is constituted by an intuitive website with a database that allows data corroboration, visualization and comparison of the 3D digital models, as well as a digital mapping in the GIS system.

3D Digital Surveying and Modelling of Cave Geometry: Application to Paleolithic Rock Art

PubMed Central

González-Aguilera, Diego; Muñoz-Nieto, Angel; Gómez-Lahoz, Javier; Herrero-Pascual, Jesus; Gutierrez-Alonso, Gabriel

2009-01-01

3D digital surveying and modelling of cave geometry represents a relevant approach for research, management and preservation of our cultural and geological legacy. In this paper, a multi-sensor approach based on a terrestrial laser scanner, a high-resolution digital camera and a total station is presented. Two emblematic caves of Paleolithic human occupation and situated in northern Spain, “Las Caldas” and “Peña de Candamo”, have been chosen to put in practise this approach. As a result, an integral and multi-scalable 3D model is generated which may allow other scientists, pre-historians, geologists…, to work on two different levels, integrating different Paleolithic Art datasets: (1) a basic level based on the accurate and metric support provided by the laser scanner; and (2) a advanced level using the range and image-based modelling. PMID:22399958

Interactive 2D to 3D stereoscopic image synthesis

NASA Astrophysics Data System (ADS)

Feldman, Mark H.; Lipton, Lenny

2005-03-01

Advances in stereoscopic display technologies, graphic card devices, and digital imaging algorithms have opened up new possibilities in synthesizing stereoscopic images. The power of today"s DirectX/OpenGL optimized graphics cards together with adapting new and creative imaging tools found in software products such as Adobe Photoshop, provide a powerful environment for converting planar drawings and photographs into stereoscopic images. The basis for such a creative process is the focus of this paper. This article presents a novel technique, which uses advanced imaging features and custom Windows-based software that utilizes the Direct X 9 API to provide the user with an interactive stereo image synthesizer. By creating an accurate and interactive world scene with moveable and flexible depth map altered textured surfaces, perspective stereoscopic cameras with both visible frustums and zero parallax planes, a user can precisely model a virtual three-dimensional representation of a real-world scene. Current versions of Adobe Photoshop provide a creative user with a rich assortment of tools needed to highlight elements of a 2D image, simulate hidden areas, and creatively shape them for a 3D scene representation. The technique described has been implemented as a Photoshop plug-in and thus allows for a seamless transition of these 2D image elements into 3D surfaces, which are subsequently rendered to create stereoscopic views.

Image Fusion Algorithms Using Human Visual System in Transform Domain

NASA Astrophysics Data System (ADS)

Vadhi, Radhika; Swamy Kilari, Veera; Samayamantula, Srinivas Kumar

2017-08-01

The endeavor of digital image fusion is to combine the important visual parts from various sources to advance the visibility eminence of the image. The fused image has a more visual quality than any source images. In this paper, the Human Visual System (HVS) weights are used in the transform domain to select appropriate information from various source images and then to attain a fused image. In this process, mainly two steps are involved. First, apply the DWT to the registered source images. Later, identify qualitative sub-bands using HVS weights. Hence, qualitative sub-bands are selected from different sources to form high quality HVS based fused image. The quality of the HVS based fused image is evaluated with general fusion metrics. The results show the superiority among the state-of-the art resolution Transforms (MRT) such as Discrete Wavelet Transform (DWT), Stationary Wavelet Transform (SWT), Contourlet Transform (CT), and Non Sub Sampled Contourlet Transform (NSCT) using maximum selection fusion rule.

Digital Image Compression Using Artificial Neural Networks

NASA Technical Reports Server (NTRS)

Serra-Ricart, M.; Garrido, L.; Gaitan, V.; Aloy, A.

1993-01-01

The problem of storing, transmitting, and manipulating digital images is considered. Because of the file sizes involved, large amounts of digitized image information are becoming common in modern projects. Our goal is to described an image compression transform coder based on artificial neural networks techniques (NNCTC). A comparison of the compression results obtained from digital astronomical images by the NNCTC and the method used in the compression of the digitized sky survey from the Space Telescope Science Institute based on the H-transform is performed in order to assess the reliability of the NNCTC.

Skin colour assessment of replanted fingers in digital images and its reliability for the incorporation of images in nursing progress notes.

PubMed

Terashima, Taiko; Yoshimura, Sadako

2018-03-01

To determine whether nurses can accurately assess the skin colour of replanted fingers displayed as digital images on a computer screen. Colour measurement and clinical diagnostic methods for medical digital images have been studied, but reproducing skin colour on a computer screen remains difficult. The inter-rater reliability of skin colour assessment scores was evaluated. In May 2014, 21 nurses who worked on a trauma ward in Japan participated in testing. Six digital images with different skin colours were used. Colours were scored from both digital images and direct patient's observation. The score from a digital image was defined as the test score, and its difference from the direct assessment score as the difference score. Intraclass correlation coefficients were calculated. Nurses' opinions were classified and summarised. The intraclass correlation coefficients for the test scores were fair. Although the intraclass correlation coefficients for the difference scores were poor, they improved to good when three images that might have contributed to poor reliability were excluded. Most nurses stated that it is difficult to assess skin colour in digital images; they did not think it could be a substitute for direct visual assessment. However, most nurses were in favour of including images in nursing progress notes. Although the inter-rater reliability was fairly high, the reliability of colour reproduction in digital images as indicated by the difference scores was poor. Nevertheless, nurses expect the incorporation of digital images in nursing progress notes to be useful. This gap between the reliability of digital colour reproduction and nurses' expectations towards it must be addressed. High inter-rater reliability for digital images in nursing progress notes was not observed. Assessments of future improvements in colour reproduction technologies are required. Further digitisation and visualisation of nursing records might pose challenges. © 2017 John Wiley & Sons Ltd.

HVS: an image-based approach for constructing virtual environments

NASA Astrophysics Data System (ADS)

Zhang, Maojun; Zhong, Li; Sun, Lifeng; Li, Yunhao

1998-09-01

Virtual Reality Systems can construct virtual environment which provide an interactive walkthrough experience. Traditionally, walkthrough is performed by modeling and rendering 3D computer graphics in real-time. Despite the rapid advance of computer graphics technique, the rendering engine usually places a limit on scene complexity and rendering quality. This paper presents a approach which uses the real-world image or synthesized image to comprise a virtual environment. The real-world image or synthesized image can be recorded by camera, or synthesized by off-line multispectral image processing for Landsat TM (Thematic Mapper) Imagery and SPOT HRV imagery. They are digitally warped on-the-fly to simulate walking forward/backward, to left/right and 360-degree watching around. We have developed a system HVS (Hyper Video System) based on these principles. HVS improves upon QuickTime VR and Surround Video in the walking forward/backward.

Analysis of identification of digital images from a map of cosmic microwaves

NASA Astrophysics Data System (ADS)

Skeivalas, J.; Turla, V.; Jurevicius, M.; Viselga, G.

2018-04-01

This paper discusses identification of digital images from the cosmic microwave background radiation map formed according to the data of the European Space Agency "Planck" telescope by applying covariance functions and wavelet theory. The estimates of covariance functions of two digital images or single images are calculated according to the random functions formed of the digital images in the form of pixel vectors. The estimates of pixel vectors are formed on expansion of the pixel arrays of the digital images by a single vector. When the scale of a digital image is varied, the frequencies of single-pixel color waves remain constant and the procedure for calculation of covariance functions is not affected. For identification of the images, the RGB format spectrum has been applied. The impact of RGB spectrum components and the color tensor on the estimates of covariance functions was analyzed. The identity of digital images is assessed according to the changes in the values of the correlation coefficients in a certain range of values by applying the developed computer program.

Digital Longitudinal Tomosynthesis

NASA Astrophysics Data System (ADS)

Rimkus, Daniel Steven

1985-12-01

The purpose of this dissertation was to investigate the clinical utility of digital longitudinal tomosynthesis in radiology. By acquiring a finite group of digital images during a longitudinal tomographic exposure, and processing these images, tomographic planes, other than the fulcrum plane, can be reconstructed. This process is now termed "tomosynthesis". A prototype system utilizing this technique was developed. Both phantom and patient studies were done with this system. The phantom studies were evaluated by subjective, visual criterion and by quantitative analysis of edge sharpness and noise in the reconstructions. Two groups of patients and one volunteer were studied. The first patient group consisted of 8 patients undergoing intravenous urography (IVU). These patients had digital tomography and film tomography of the abdomen. The second patient group consisted of 4 patients with lung cancer admitted to the hospital for laser resection of endobronchial tumor. These patients had mediastinal digital tomograms to evaluate the trachea and mainstem bronchi. The knee of one volunteer was imaged by film tomography and digital tomography. The results of the phantom studies showed that the digital reconstructions accurately produced images of the desired planes. The edge sharpness of the reconstructions approached that of the acquired images. Adequate reconstructions were achieved with as few as 5 images acquired during the exposure, with the quality of the reconstructions improving as the number of images acquired increased. The IVU patients' digital studies had less contrast and spatial resolution than the film tomograms. The single renal lesion visible on the film tomograms was also visible in the digital images. The digital mediastinal studies were felt by several radiologists to be superior to a standard chest xray in evaluating the airways. The digital images of the volunteer's knee showed many of the same anatomic features as the film tomogram, but the digital images had less spatial and contrast resolution. With the equipment improvements discussed in the thesis, digital tomography may have an important role in radiology.

Handwritten mathematical symbols dataset.

PubMed

Chajri, Yassine; Bouikhalene, Belaid

2016-06-01

Due to the technological advances in recent years, paper scientific documents are used less and less. Thus, the trend in the scientific community to use digital documents has increased considerably. Among these documents, there are scientific documents and more specifically mathematics documents. In this context, we present our own dataset of handwritten mathematical symbols composed of 10,379 images. This dataset gathers Arabic characters, Latin characters, Arabic numerals, Latin numerals, arithmetic operators, set-symbols, comparison symbols, delimiters, etc.

Sea Ice in the Bellingshausen Sea

NASA Image and Video Library

2017-12-08

Antarctica—the continent at the southernmost reach of the planet—is fringed by cold, often frozen waters of the Southern Ocean. The extent of sea ice around the continent typically reaches a peak in September and a minimum in February. The photograph above shows Antarctic sea ice on November 5, 2014, during the annual cycle of melt. The image was acquired by the Digital Mapping System (DMS), a digital camera installed in the belly of research aircraft to capture images of terrain below. In this case, the system flew on the DC-8 during a flight as part of NASA’s Operation IceBridge. Most of the view shows first-year sea ice in the Bellingshausen Sea, as it appeared from an altitude of 328 meters (1,076 feet). The block of ice on the right side of the image is older, thicker, and was once attached to the Antarctic Ice Sheet. By the time this image was acquired, however, the ice had broken away to form an iceberg. Given its close proximity to the ice sheet, this could have been a relatively new berg. Read more: earthobservatory.nasa.gov/IOTD/view.php?id=86721 Credit: NASA/Goddard/IceBridge DMS L0 Raw Imagery courtesy of the Digital Mapping System (DMS) team and the NASA DAAC at the National Snow and Ice Data Center Credit: NASA Earth Observatory NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Cost-effective handling of digital medical images in the telemedicine environment.

PubMed

Choong, Miew Keen; Logeswaran, Rajasvaran; Bister, Michel

2007-09-01

This paper concentrates on strategies for less costly handling of medical images. Aspects of digitization using conventional digital cameras, lossy compression with good diagnostic quality, and visualization through less costly monitors are discussed. For digitization of film-based media, subjective evaluation of the suitability of digital cameras as an alternative to the digitizer was undertaken. To save on storage, bandwidth and transmission time, the acceptable degree of compression with diagnostically no loss of important data was studied through randomized double-blind tests of the subjective image quality when compression noise was kept lower than the inherent noise. A diagnostic experiment was undertaken to evaluate normal low cost computer monitors as viable viewing displays for clinicians. The results show that conventional digital camera images of X-ray images were diagnostically similar to the expensive digitizer. Lossy compression, when used moderately with the imaging noise to compression noise ratio (ICR) greater than four, can bring about image improvement with better diagnostic quality than the original image. Statistical analysis shows that there is no diagnostic difference between expensive high quality monitors and conventional computer monitors. The results presented show good potential in implementing the proposed strategies to promote widespread cost-effective telemedicine and digital medical environments. 2006 Elsevier Ireland Ltd

Validated System for Centralized Grading of Retinopathy of Prematurity: Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study.

PubMed

Daniel, Ebenezer; Quinn, Graham E; Hildebrand, P Lloyd; Ells, Anna; Hubbard, G Baker; Capone, Antonio; Martin, E Revell; Ostroff, Candace P; Smith, Eli; Pistilli, Maxwell; Ying, Gui-Shuang

2015-06-01

Measurable competence derived from comprehensive and advanced training in grading digital images is critical in studies using a reading center to evaluate retinal fundus images from infants at risk for retinopathy of prematurity (ROP). Details of certification for nonphysician trained readers (TRs) have not yet been described. To describe a centralized system for grading ROP digital images by TRs in the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study. Multicenter observational cohort study conducted from July 1, 2010, to June 30, 2014. The TRs were trained by experienced ROP specialists and certified to detect ROP morphology in digital retinal images under supervision of an ophthalmologist reading center director. An ROP reading center was developed with standard hardware, secure Internet access, and customized image viewing software with an electronic grading form. A detailed protocol for grading was developed. Based on results of TR gradings, a computerized algorithm determined whether referral-warranted ROP (RW-ROP; defined as presence of plus disease, zone I ROP, and stage 3 or worse ROP) was present in digital images from infants with birth weight less than 1251 g enrolled from May 25, 2011, through October 31, 2013. Independent double grading was done by the TRs with adjudication of discrepant fields performed by the reading center director. Digital retinal images. Intragrader and intergrader variability and monitoring for temporal drift. Four TRs underwent rigorous training and certification. A total of 5520 image sets were double graded, with 24.5% requiring adjudication for at least 1 component of RW-ROP. For individual RW-ROP components, the adjudication rate was 3.9% for plus disease, 12.4% for zone I ROP, and 16.9% for stage 3 or worse ROP. The weighted κ for intergrader agreement (n = 80 image sets) was 0.72 (95% CI, 0.52-0.93) for RW-ROP, 0.57 (95% CI, 0.37-0.77) for plus disease, 0.43 (95% CI, 0.24-0.63) for zone I ROP, and 0.67 (95% CI, 0.47-0.88) for stage 3 or worse ROP. The weighted κ for grade-regrade agreement was 0.77 (95% CI, 0.57-0.97) for RW-ROP, 0.87 (95% CI, 0.67-1.00) for plus disease, 0.70 (95% CI, 0.51-0.90) for zone I ROP, and 0.77 (95% CI, 0.57-0.97) for stage 3 or worse ROP. These data suggest that the e-ROP system for training and certifying nonphysicians to grade ROP images under the supervision of a reading center director reliably detects potentially serious ROP with good intragrader and intergrader consistency and minimal temporal drift.

Processing, mosaicking and management of the Monterey Bay digital sidescan-sonar images

USGS Publications Warehouse

Chavez, P.S.; Isbrecht, J.; Galanis, P.; Gabel, G.L.; Sides, S.C.; Soltesz, D.L.; Ross, Stephanie L.; Velasco, M.G.

2002-01-01

Sidescan-sonar imaging systems with digital capabilities have now been available for approximately 20 years. In this paper we present several of the various digital image processing techniques developed by the U.S. Geological Survey (USGS) and used to apply intensity/radiometric and geometric corrections, as well as enhance and digitally mosaic, sidescan-sonar images of the Monterey Bay region. New software run by a WWW server was designed and implemented to allow very large image data sets, such as the digital mosaic, to be easily viewed interactively, including the ability to roam throughout the digital mosaic at the web site in either compressed or full 1-m resolution. The processing is separated into the two different stages: preprocessing and information extraction. In the preprocessing stage, sensor-specific algorithms are applied to correct for both geometric and intensity/radiometric distortions introduced by the sensor. This is followed by digital mosaicking of the track-line strips into quadrangle format which can be used as input to either visual or digital image analysis and interpretation. An automatic seam removal procedure was used in combination with an interactive digital feathering/stenciling procedure to help minimize tone or seam matching problems between image strips from adjacent track-lines. The sidescan-sonar image processing package is part of the USGS Mini Image Processing System (MIPS) and has been designed to process data collected by any 'generic' digital sidescan-sonar imaging system. The USGS MIPS software, developed over the last 20 years as a public domain package, is available on the WWW at: http://terraweb.wr.usgs.gov/trs/software.html.

Satellite Imagery Via Personal Computer

NASA Technical Reports Server (NTRS)

1989-01-01

Automatic Picture Transmission (APT) was incorporated by NASA in the Tiros 8 weather satellite. APT included an advanced satellite camera that immediately transmitted a picture as well as low cost receiving equipment. When an advanced scanning radiometer was later introduced, ground station display equipment would not readily adjust to the new format until GSFC developed an APT Digital Scan Converter that made them compatible. A NASA Technical Note by Goddard's Vermillion and Kamoski described how to build a converter. In 1979, Electro-Services, using this technology, built the first microcomputer weather imaging system in the U.S. The company changed its name to Satellite Data Systems, Inc. and now manufactures the WeatherFax facsimile display graphics system which converts a personal computer into a weather satellite image acquisition and display workstation. Hardware, antennas, receivers, etc. are also offered. Customers include U.S. Weather Service, schools, military, etc.

Third molar development in a contemporary Danish 13-25year old population.

PubMed

Arge, Sara; Boldsen, Jesper Lier; Wenzel, Ann; Holmstrup, Palle; Jensen, Niels Dyrgaard; Lynnerup, Niels

2018-05-16

We present a reference database for third molar development based on a contemporary Danish population. A total of 1302 digital panoramic images were evaluated. The images were taken at a known chronological age, ranging from 13 to 25years. Third molar development was scored according to the Köhler modification of the 10-stage method of Gleiser and Hunt. We found that third molar development was generally advanced in the maxilla compared to the mandible and in males compared to females; in addition, the mandibular third molar mesial roots were generally more advanced in development than were the distal roots. There was no difference in third molar development between the left and right side of the jaws. Establishing global and robust databases on dental development is crucial for further development of forensic methods to evaluate age. Copyright © 2018. Published by Elsevier B.V.

Low-cost conversion of the Polaroid MD-4 land camera to a digital gel documentation system.

PubMed

Porch, Timothy G; Erpelding, John E

2006-04-30

A simple, inexpensive design is presented for the rapid conversion of the popular MD-4 Polaroid land camera to a high quality digital gel documentation system. Images of ethidium bromide stained DNA gels captured using the digital system were compared to images captured on Polaroid instant film. Resolution and sensitivity were enhanced using the digital system. In addition to the low cost and superior image quality of the digital system, there is also the added convenience of real-time image viewing through the swivel LCD of the digital camera, wide flexibility of gel sizes, accurate automatic focusing, variable image resolution, and consistent ease of use and quality. Images can be directly imported to a computer by using the USB port on the digital camera, further enhancing the potential of the digital system for documentation, analysis, and archiving. The system is appropriate for use as a start-up gel documentation system and for routine gel analysis.

Programmable Remapper with Single Flow Architecture

NASA Technical Reports Server (NTRS)

Fisher, Timothy E. (Inventor)

1993-01-01

An apparatus for image processing comprising a camera for receiving an original visual image and transforming the original visual image into an analog image, a first converter for transforming the analog image of the camera to a digital image, a processor having a single flow architecture for receiving the digital image and producing, with a single algorithm, an output image, a second converter for transforming the digital image of the processor to an analog image, and a viewer for receiving the analog image, transforming the analog image into a transformed visual image for observing the transformations applied to the original visual image. The processor comprises one or more subprocessors for the parallel reception of a digital image for producing an output matrix of the transformed visual image. More particularly, the processor comprises a plurality of subprocessors for receiving in parallel and transforming the digital image for producing a matrix of the transformed visual image, and an output interface means for receiving the respective portions of the transformed visual image from the respective subprocessor for producing an output matrix of the transformed visual image.

Digital Imaging and the Cognitive Revolution: A Media Challenge.

ERIC Educational Resources Information Center

Sartorius, Ute

This paper discusses the role of digital technology within the cognitive revolution of the perception of images. It analyzes the traditional values placed on images as a source of cognition. These values are discussed in terms of the ethical and social issues raised by the use of digital image manipulation in so far as the digital era is falsely…

Development of an MRI-compatible digital SiPM detector stack for simultaneous PET/MRI

PubMed Central

Düppenbecker, Peter M; Weissler, Bjoern; Gebhardt, Pierre; Schug, David; Wehner, Jakob; Marsden, Paul K; Schulz, Volkmar

2016-01-01

Abstract Advances in solid-state photon detectors paved the way to combine positron emission tomography (PET) and magnetic resonance imaging (MRI) into highly integrated, truly simultaneous, hybrid imaging systems. Based on the most recent digital SiPM technology, we developed an MRI-compatible PET detector stack, intended as a building block for next generation simultaneous PET/MRI systems. Our detector stack comprises an array of 8 × 8 digital SiPM channels with 4 mm pitch using Philips Digital Photon Counting DPC 3200-22 devices, an FPGA for data acquisition, a supply voltage control system and a cooling infrastructure. This is the first detector design that allows the operation of digital SiPMs simultaneously inside an MRI system. We tested and optimized the MRI-compatibility of our detector stack on a laboratory test bench as well as in combination with a Philips Achieva 3 T MRI system. Our design clearly reduces distortions of the static magnetic field compared to a conventional design. The MRI static magnetic field causes weak and directional drift effects on voltage regulators, but has no direct impact on detector performance. MRI gradient switching initially degraded energy and timing resolution. Both distortions could be ascribed to voltage variations induced on the bias and the FPGA core voltage supply respectively. Based on these findings, we improved our detector design and our final design shows virtually no energy or timing degradations, even during heavy and continuous MRI gradient switching. In particular, we found no evidence that the performance of the DPC 3200-22 digital SiPM itself is degraded by the MRI system. PMID:28458919

Digital photography for the light microscope: results with a gated, video-rate CCD camera and NIH-image software.

PubMed

Shaw, S L; Salmon, E D; Quatrano, R S

1995-12-01

In this report, we describe a relatively inexpensive method for acquiring, storing and processing light microscope images that combines the advantages of video technology with the powerful medium now termed digital photography. Digital photography refers to the recording of images as digital files that are stored, manipulated and displayed using a computer. This report details the use of a gated video-rate charge-coupled device (CCD) camera and a frame grabber board for capturing 256 gray-level digital images from the light microscope. This camera gives high-resolution bright-field, phase contrast and differential interference contrast (DIC) images but, also, with gated on-chip integration, has the capability to record low-light level fluorescent images. The basic components of the digital photography system are described, and examples are presented of fluorescence and bright-field micrographs. Digital processing of images to remove noise, to enhance contrast and to prepare figures for printing is discussed.

Current State of the Regulatory Trajectory for Whole Slide Imaging Devices in the USA

PubMed Central

Abels, Esther; Pantanowitz, Liron

2017-01-01

The regulatory field for digital pathology (DP) has advanced significantly. A major milestone was accomplished when the FDA allowed the first vendor to market their device for primary diagnostic use in the USA and published in the classification order that this device, and substantially equivalent devices of this generic type, should be classified into class II instead of class III as previously proposed. The Digital Pathology Association (DPA) regulatory task force had a major role in the accomplishment of getting the application request for Whole Slide Imaging (WSI) Systems recommended for a de novo. This article reviews the past and emerging regulatory environment of WSI for clinical use in the USA. A WSI system with integrated subsystems is defined in the context of medical device regulations. The FDA technical performance assessment guideline is also discussed as well as parameters involved in analytical testing and clinical studies to demonstrate that WSI devices are safe and effective for clinical use. PMID:28584684

Current State of the Regulatory Trajectory for Whole Slide Imaging Devices in the USA.

PubMed

Abels, Esther; Pantanowitz, Liron

2017-01-01

The regulatory field for digital pathology (DP) has advanced significantly. A major milestone was accomplished when the FDA allowed the first vendor to market their device for primary diagnostic use in the USA and published in the classification order that this device, and substantially equivalent devices of this generic type, should be classified into class II instead of class III as previously proposed. The Digital Pathology Association (DPA) regulatory task force had a major role in the accomplishment of getting the application request for Whole Slide Imaging (WSI) Systems recommended for a de novo . This article reviews the past and emerging regulatory environment of WSI for clinical use in the USA. A WSI system with integrated subsystems is defined in the context of medical device regulations. The FDA technical performance assessment guideline is also discussed as well as parameters involved in analytical testing and clinical studies to demonstrate that WSI devices are safe and effective for clinical use.

Results of calibrations of the NOAA-11 AVHRR made by reference to calibrated SPOT imagery at White Sands, N.M

NASA Technical Reports Server (NTRS)

Nianzeng, Che; Grant, Barbara G.; Flittner, David E.; Slater, Philip N.; Biggar, Stuart F.; Jackson, Ray D.; Moran, M. S.

1991-01-01

The calibration method reported here makes use of the reflectances of several large, uniform areas determined from calibrated and atmospherically corrected SPOT Haute Resolution Visible (HRV) scenes of White Sands, New Mexico. These reflectances were used to predict the radiances in the first two channels of the NOAA-11 Advanced Very High Resolution Radiometer (AVHRR). The digital counts in the AVHRR image corresponding to these known reflectance areas were determined by the use of two image registration techniques. The plots of digital counts versus pixel radiance provided the calibration gains and offsets for the AVHRR. A reduction in the gains of 4 and 13 percent in channels 1 and 2 respectively was found during the period 1988-11-19 to 1990-6-21. An error budget is presented for the method and is extended to the case of cross-calibrating sensors on the same orbital platform in the Earth Observing System (EOS) era.

Remote measurement methods for 3-D modeling purposes using BAE Systems' Software

NASA Astrophysics Data System (ADS)

Walker, Stewart; Pietrzak, Arleta

2015-06-01

Efficient, accurate data collection from imagery is the key to an economical generation of useful geospatial products. Incremental developments of traditional geospatial data collection and the arrival of new image data sources cause new software packages to be created and existing ones to be adjusted to enable such data to be processed. In the past, BAE Systems' digital photogrammetric workstation, SOCET SET®, met fin de siècle expectations in data processing and feature extraction. Its successor, SOCET GXP®, addresses today's photogrammetric requirements and new data sources. SOCET GXP is an advanced workstation for mapping and photogrammetric tasks, with automated functionality for triangulation, Digital Elevation Model (DEM) extraction, orthorectification and mosaicking, feature extraction and creation of 3-D models with texturing. BAE Systems continues to add sensor models to accommodate new image sources, in response to customer demand. New capabilities added in the latest version of SOCET GXP facilitate modeling, visualization and analysis of 3-D features.

Mechanical analysis and force chain determination in granular materials using digital image correlation.

PubMed

Chen, Fanxiu; Zhuang, Qi; Zhang, Huixin

2016-06-20

The mechanical behaviors of granular materials are governed by the grain properties and microstructure of the materials. We conducted experiments to study the force transmission in granular materials using plane strain tests. The large amount of nearly continuous displacement data provided by the advanced noncontact experimental technique of digital image correlation (DIC) has provided a means to quantify local displacements and strains at the particle level. The average strain of each particle could be calculated based on the DIC method, and the average stress could be obtained using Hooke's law. The relationship between the stress and particle force could be obtained based on basic Newtonian mechanics and the balance of linear momentum at the particle level. This methodology is introduced and validated. In the testing procedure, the system is tested in real 2D particle cases, and the contact forces and force chain are obtained and analyzed. The system has great potential for analyzing a real granular system and measuring the contact forces and force chain.

Digital management and regulatory submission of medical images from clinical trials: role and benefits of the core laboratory

NASA Astrophysics Data System (ADS)

Robbins, William L.; Conklin, James J.

1995-10-01

Medical images (angiography, CT, MRI, nuclear medicine, ultrasound, x ray) play an increasingly important role in the clinical development and regulatory review process for pharmaceuticals and medical devices. Since medical images are increasingly acquired and archived digitally, or are readily digitized from film, they can be visualized, processed and analyzed in a variety of ways using digital image processing and display technology. Moreover, with image-based data management and data visualization tools, medical images can be electronically organized and submitted to the U.S. Food and Drug Administration (FDA) for review. The collection, processing, analysis, archival, and submission of medical images in a digital format versus an analog (film-based) format presents both challenges and opportunities for the clinical and regulatory information management specialist. The medical imaging 'core laboratory' is an important resource for clinical trials and regulatory submissions involving medical imaging data. Use of digital imaging technology within a core laboratory can increase efficiency and decrease overall costs in the image data management and regulatory review process.

Use of a remote computer terminal during field checking of Landsat digital maps

USGS Publications Warehouse

Robinove, Charles J.; Hutchinson, C.F.

1978-01-01

Field checking of small-scale land classification maps made digitally from Landsat data is facilitated by use of a remote portable teletypewriter terminal linked by teleplume to the IDIMS (Interactive Digital Image Manipulation System) at the EDC (EROS Data Center), Sioux Falls, S. Dak. When field checking of maps 20 miles northeast of Baker, Calif., during the day showed that changes in classification were needed, the terminal was used at night to combine image statistical files, remap portions of images, and produce new alphanumeric maps for field checking during the next day. The alphanumeric maps can be used without serious difficulty in location in the field even though the scale is distorted, and statistical files created during the field check can be used for full image classification and map output at the EDC. This process makes field checking faster than normal, provides interaction with the statistical data while in the field, and reduces to a minimum the number of trips needed to work interactively with the IDIMS at the EDC, thus saving significant amounts of time and money. The only significant problem is using telephone lines which at times create spurious characters in the printout or prevent the line feed (paper advance) signal from reaching the terminal, thus overprinting lines which should be sequential. We recommend that maps for field checking be made with more spectral classes than are expected because in the field it is much easier to group classes than to reclassify or separate classes when only the remote terminal is available for display.

Optomechanical System Development of the AWARE Gigapixel Scale Camera

NASA Astrophysics Data System (ADS)

Son, Hui S.

Electronic focal plane arrays (FPA) such as CMOS and CCD sensors have dramatically improved to the point that digital cameras have essentially phased out film (except in very niche applications such as hobby photography and cinema). However, the traditional method of mating a single lens assembly to a single detector plane, as required for film cameras, is still the dominant design used in cameras today. The use of electronic sensors and their ability to capture digital signals that can be processed and manipulated post acquisition offers much more freedom of design at system levels and opens up many interesting possibilities for the next generation of computational imaging systems. The AWARE gigapixel scale camera is one such computational imaging system. By utilizing a multiscale optical design, in which a large aperture objective lens is mated with an array of smaller, well corrected relay lenses, we are able to build an optically simple system that is capable of capturing gigapixel scale images via post acquisition stitching of the individual pictures from the array. Properly shaping the array of digital cameras allows us to form an effectively continuous focal surface using off the shelf (OTS) flat sensor technology. This dissertation details developments and physical implementations of the AWARE system architecture. It illustrates the optomechanical design principles and system integration strategies we have developed through the course of the project by summarizing the results of the two design phases for AWARE: AWARE-2 and AWARE-10. These systems represent significant advancements in the pursuit of scalable, commercially viable snapshot gigapixel imaging systems and should serve as a foundation for future development of such systems.

How Advances in Imaging Will Affect Precision Radiation Oncology.

PubMed

Jaffray, David A; Das, Shiva; Jacobs, Paula M; Jeraj, Robert; Lambin, Philippe

2018-06-01

Radiation oncology is 1 of the most structured disciplines in medicine. It is of a highly technical nature with reliance on robotic systems to deliver intervention, engagement of diverse expertise, and early adoption of digital approaches to optimize and execute the application of this highly effective cancer treatment. As a localized intervention, the dependence on sensitive, specific, and accurate imaging to define the extent of disease, its heterogeneity, and adjacency to normal tissues directly affects the therapeutic ratio. Image-based in vivo temporal monitoring of the response to treatment enables adaptation and further affects the therapeutic ratio. Thus, more precise intervention will enable fractionation schedules that better interoperate with advances such as immunotherapy. In the data set-rich era that promises precision and personalized medicine, the radiation oncology field will integrate these new data into highly protocoled pathways of care that begin with multimodality prediction and enable patient-specific adaptation of therapy based on quantitative measures of the individual's dose-volume temporal trajectory and midtherapy predictions of response. In addition to advancements in computed tomography imaging, emerging technologies, such as ultra-high-field magnetic resonance and molecular imaging will bring new information to the design of treatments. Next-generation image guided radiation therapy systems will inject high specificity and sensitivity data and stimulate adaptive replanning. In addition, a myriad of pre- and peritherapeutic markers derived from advances in molecular pathology (eg, tumor genomics), automated and comprehensive imaging analytics (eg, radiomics, tumor microenvironment), and many other emerging biomarkers (eg, circulating tumor cell assays) will need to be integrated to maximize the benefit of radiation therapy for an individual patient. We present a perspective on the promise and challenges of fully exploiting imaging data in the pursuit of personalized radiation therapy, drawing from the presentations and broader discussions at the 2016 American Society of Therapeutic Radiation Oncology-National Cancer Institute workshop on Precision Medicine in Radiation Oncology (Bethesda, MD). Copyright © 2018. Published by Elsevier Inc.

Illumination-tolerant face verification of low-bit-rate JPEG2000 wavelet images with advanced correlation filters for handheld devices

NASA Astrophysics Data System (ADS)

Wijaya, Surya Li; Savvides, Marios; Vijaya Kumar, B. V. K.

2005-02-01

Face recognition on mobile devices, such as personal digital assistants and cell phones, is a big challenge owing to the limited computational resources available to run verifications on the devices themselves. One approach is to transmit the captured face images by use of the cell-phone connection and to run the verification on a remote station. However, owing to limitations in communication bandwidth, it may be necessary to transmit a compressed version of the image. We propose using the image compression standard JPEG2000, which is a wavelet-based compression engine used to compress the face images to low bit rates suitable for transmission over low-bandwidth communication channels. At the receiver end, the face images are reconstructed with a JPEG2000 decoder and are fed into the verification engine. We explore how advanced correlation filters, such as the minimum average correlation energy filter [Appl. Opt. 26, 3633 (1987)] and its variants, perform by using face images captured under different illumination conditions and encoded with different bit rates under the JPEG2000 wavelet-encoding standard. We evaluate the performance of these filters by using illumination variations from the Carnegie Mellon University's Pose, Illumination, and Expression (PIE) face database. We also demonstrate the tolerance of these filters to noisy versions of images with illumination variations.

Accessible biometrics: A frustrated total internal reflection approach to imaging fingerprints.

PubMed

Smith, Nathan D; Sharp, James S

2017-05-01

Fingerprints are widely used as a means of identifying persons of interest because of the highly individual nature of the spatial distribution and types of features (or minuta) found on the surface of a finger. This individuality has led to their wide application in the comparison of fingerprints found at crime scenes with those taken from known offenders and suspects in custody. However, despite recent advances in machine vision technology and image processing techniques, fingerprint evidence is still widely being collected using outdated practices involving ink and paper - a process that can be both time consuming and expensive. Reduction of forensic service budgets increasingly requires that evidence be gathered and processed more rapidly and efficiently. However, many of the existing digital fingerprint acquisition devices have proven too expensive to roll out on a large scale. As a result new, low-cost imaging technologies are required to increase the quality and throughput of the processing of fingerprint evidence. Here we describe an inexpensive approach to digital fingerprint acquisition that is based upon frustrated total internal reflection imaging. The quality and resolution of the images produced are shown to be as good as those currently acquired using ink and paper based methods. The same imaging technique is also shown to be capable of imaging powdered fingerprints that have been lifted from a crime scene using adhesive tape or gel lifters. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.

Programmable spectral engine design of hyperspectral image projectors based on digital micro-mirror device (DMD)

NASA Astrophysics Data System (ADS)

Wang, Xicheng; Gao, Jiaobo; Wu, Jianghui; Li, Jianjun; Cheng, Hongliang

2017-02-01

Recently, hyperspectral image projectors (HIP) have been developed in the field of remote sensing. For the advanced performance of system-level validation, target detection and hyperspectral image calibration, HIP has great possibility of development in military, medicine, commercial and so on. HIP is based on the digital micro-mirror device (DMD) and projection technology, which is capable to project arbitrary programmable spectra (controlled by PC) into the each pixel of the IUT1 (instrument under test), such that the projected image could simulate realistic scenes that hyperspectral image could be measured during its use and enable system-level performance testing and validation. In this paper, we built a visible hyperspectral image projector also called the visible target simulator with double DMDs, which the first DMD is used to product the selected monochromatic light from the wavelength of 410 to 720 um, and the light come to the other one. Then we use computer to load image of realistic scenes to the second DMD, so that the target condition and background could be project by the second DMD with the selected monochromatic light. The target condition can be simulated and the experiment could be controlled and repeated in the lab, making the detector instrument could be tested in the lab. For the moment, we make the focus on the spectral engine design include the optical system, research of DMD programmable spectrum and the spectral resolution of the selected spectrum. The detail is shown.

Magnetic resonance imaging of the normal bovine digit.

PubMed

Raji, A R; Sardari, K; Mirmahmoob, P

2009-08-01

The purpose of this study was defining the normal structures of the digits and hoof in Holstein dairy cattle using Magnetic Resonance Image (MRI). Transverse, Sagital and Dorsoplantar MRI images of three isolated cattle cadaver digits were obtained using Gyroscan T5-NT a magnet of 0.5 Tesla and T1 Weighted sequence. The MRI images were compared to corresponding frozen cross-sections and dissect specimens of the cadaver digits. Relevant anatomical structures were identified and labeled at each level. The MRI images provided anatomical detail of the digits and hoof in Holstein dairy cattle. Transversal images provided excellent depiction of anatomical structures when compared to corresponding frozen cross-sections. The information presented in this paper would serve as an initial reference to the evaluation of MRI images of the digits and hoof in Holstein dairy cattle, that can be used by radiologist, clinicians, surgeon or for research propose in bovine lameness.

[Development of a digital chest phantom for studies on energy subtraction techniques].

PubMed

Hayashi, Norio; Taniguchi, Anna; Noto, Kimiya; Shimosegawa, Masayuki; Ogura, Toshihiro; Doi, Kunio

2014-03-01

Digital chest phantoms continue to play a significant role in optimizing imaging parameters for chest X-ray examinations. The purpose of this study was to develop a digital chest phantom for studies on energy subtraction techniques under ideal conditions without image noise. Computed tomography (CT) images from the LIDC (Lung Image Database Consortium) were employed to develop a digital chest phantom. The method consisted of the following four steps: 1) segmentation of the lung and bone regions on CT images; 2) creation of simulated nodules; 3) transformation to attenuation coefficient maps from the segmented images; and 4) projection from attenuation coefficient maps. To evaluate the usefulness of digital chest phantoms, we determined the contrast of the simulated nodules in projection images of the digital chest phantom using high and low X-ray energies, soft tissue images obtained by energy subtraction, and "gold standard" images of the soft tissues. Using our method, the lung and bone regions were segmented on the original CT images. The contrast of simulated nodules in soft tissue images obtained by energy subtraction closely matched that obtained using the gold standard images. We thus conclude that it is possible to carry out simulation studies based on energy subtraction techniques using the created digital chest phantoms. Our method is potentially useful for performing simulation studies for optimizing the imaging parameters in chest X-ray examinations.

Digital Forensics Using Local Signal Statistics

ERIC Educational Resources Information Center

Pan, Xunyu

2011-01-01

With the rapid growth of the Internet and the popularity of digital imaging devices, digital imagery has become our major information source. Meanwhile, the development of digital manipulation techniques employed by most image editing software brings new challenges to the credibility of photographic images as the definite records of events. We…

Preliminary design and implementation of the baseline digital baseband architecture for advanced deep space transponders

NASA Technical Reports Server (NTRS)

Nguyen, T. M.; Yeh, H.-G.

1993-01-01

The baseline design and implementation of the digital baseband architecture for advanced deep space transponders is investigated and identified. Trade studies on the selection of the number of bits for the analog-to-digital converter (ADC) and optimum sampling schemes are presented. In addition, the proposed optimum sampling scheme is analyzed in detail. Descriptions of possible implementations for the digital baseband (or digital front end) and digital phase-locked loop (DPLL) for carrier tracking are also described.

Lensless on-chip imaging of cells provides a new tool for high-throughput cell-biology and medical diagnostics.

PubMed

Mudanyali, Onur; Erlinger, Anthony; Seo, Sungkyu; Su, Ting-Wei; Tseng, Derek; Ozcan, Aydogan

2009-12-14

Conventional optical microscopes image cells by use of objective lenses that work together with other lenses and optical components. While quite effective, this classical approach has certain limitations for miniaturization of the imaging platform to make it compatible with the advanced state of the art in microfluidics. In this report, we introduce experimental details of a lensless on-chip imaging concept termed LUCAS (Lensless Ultra-wide field-of-view Cell monitoring Array platform based on Shadow imaging) that does not require any microscope objectives or other bulky optical components to image a heterogeneous cell solution over an ultra-wide field of view that can span as large as approximately 18 cm(2). Moreover, unlike conventional microscopes, LUCAS can image a heterogeneous cell solution of interest over a depth-of-field of approximately 5 mm without the need for refocusing which corresponds to up to approximately 9 mL sample volume. This imaging platform records the shadows (i.e., lensless digital holograms) of each cell of interest within its field of view, and automated digital processing of these cell shadows can determine the type, the count and the relative positions of cells within the solution. Because it does not require any bulky optical components or mechanical scanning stages it offers a significantly miniaturized platform that at the same time reduces the cost, which is quite important for especially point of care diagnostic tools. Furthermore, the imaging throughput of this platform is orders of magnitude better than conventional optical microscopes, which could be exceedingly valuable for high-throughput cell-biology experiments.

Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics

PubMed Central

Mudanyali, Onur; Erlinger, Anthony; Seo, Sungkyu; Su, Ting-Wei; Tseng, Derek; Ozcan, Aydogan

2009-01-01

Conventional optical microscopes image cells by use of objective lenses that work together with other lenses and optical components. While quite effective, this classical approach has certain limitations for miniaturization of the imaging platform to make it compatible with the advanced state of the art in microfluidics. In this report, we introduce experimental details of a lensless on-chip imaging concept termed LUCAS (Lensless Ultra-wide field-of-view Cell monitoring Array platform based on Shadow imaging) that does not require any microscope objectives or other bulky optical components to image a heterogeneous cell solution over an ultra-wide field of view that can span as large as ~18 cm2. Moreover, unlike conventional microscopes, LUCAS can image a heterogeneous cell solution of interest over a depth-of-field of ~5 mm without the need for refocusing which corresponds to up to ~9 mL sample volume. This imaging platform records the shadows (i.e., lensless digital holograms) of each cell of interest within its field of view, and automated digital processing of these cell shadows can determine the type, the count and the relative positions of cells within the solution. Because it does not require any bulky optical components or mechanical scanning stages it offers a significantly miniaturized platform that at the same time reduces the cost, which is quite important for especially point of care diagnostic tools. Furthermore, the imaging throughput of this platform is orders of magnitude better than conventional optical microscopes, which could be exceedingly valuable for high-throughput cell-biology experiments. PMID:20010542

Overview of benefits, challenges, and requirements of wheeled-vehicle mounted infrared sensors

NASA Astrophysics Data System (ADS)

Miller, John Lester; Clayton, Paul; Olsson, Stefan F.

2013-06-01

Requirements for vehicle mounted infrared sensors, especially as imagers evolve to high definition (HD) format will be detailed and analyzed. Lessons learned from integrations of infrared sensors on armored vehicles, unarmored military vehicles and commercial automobiles will be discussed. Comparisons between sensors for driving and those for situation awareness, targeting and other functions will be presented. Conclusions will be drawn regarding future applications and installations. New business requirements for more advanced digital image processing algorithms in the sensor system will be discussed. Examples of these are smarter contrast/brightness adjustments algorithms, detail enhancement, intelligent blending (IR-Vis) modes, and augmented reality.

Characterizing the scientific potential of satellite sensors. [San Francisco, California

NASA Technical Reports Server (NTRS)

1984-01-01

Analytical and programming support is to be provided to characterize the potential of the LANDSAT thematic mapper (TM) digital imagery for scientific investigations in the Earth sciences and in terrestrial physics. In addition, technical support to define lower atmospheric and terrestrial surface experiments for the space station and technical support to the Research Optical Sensor (ROS) study scientist for advanced studies in remote sensing are to be provided. Eleven radiometric calibration and correction programs are described. Coherent noise and bright target saturation correction are discussed along with image processing on the LAS/VAX and Hp-300/IDIMS. An image of San Francisco, California from TM band 2 is presented.

Data Acquisition System for Silicon Ultra Fast Cameras for Electron and Gamma Sources in Medical Applications (sucima Imager)

NASA Astrophysics Data System (ADS)

Czermak, A.; Zalewska, A.; Dulny, B.; Sowicki, B.; Jastrząb, M.; Nowak, L.

2004-07-01

The needs for real time monitoring of the hadrontherapy beam intensity and profile as well as requirements for the fast dosimetry using Monolithic Active Pixel Sensors (MAPS) forced the SUCIMA collaboration to the design of the unique Data Acquisition System (DAQ SUCIMA Imager). The DAQ system has been developed on one of the most advanced XILINX Field Programmable Gate Array chip - VERTEX II. The dedicated multifunctional electronic board for the detector's analogue signals capture, their parallel digital processing and final data compression as well as transmission through the high speed USB 2.0 port has been prototyped and tested.

Optical Counterpart to MAXI J1647-227

NASA Astrophysics Data System (ADS)

Garnavich, P.; Magno, K.; Applegate, A.

2012-06-01

We observed the field of the X-ray transient MAXI J1647-227 (Negoro et al., ATEL#4175) with the Vatican Advance Technology Telescope (VATT) and VATT4K CCD imager beginning June 16.244 UT. R-band images reveal an optical source near the position of the Swift localization (Kennea et al., ATEL#4178) that is not visible on the Digitized Sky Survey. Based on USNO-B1.0 catalog stars in the field, we find the optical transient has a position of 16:48:12.32 -23:00:53.56 (error of 0.2 arcsec) which is within 2 arcsec of the Swift X-ray position.

Animal-Free Chemical Safety Assessment

PubMed Central

Loizou, George D.

2016-01-01

The exponential growth of the Internet of Things and the global popularity and remarkable decline in cost of the mobile phone is driving the digital transformation of medical practice. The rapidly maturing digital, non-medical world of mobile (wireless) devices, cloud computing and social networking is coalescing with the emerging digital medical world of omics data, biosensors and advanced imaging which offers the increasingly realistic prospect of personalized medicine. Described as a potential “seismic” shift from the current “healthcare” model to a “wellness” paradigm that is predictive, preventative, personalized and participatory, this change is based on the development of increasingly sophisticated biosensors which can track and measure key biochemical variables in people. Additional key drivers in this shift are metabolomic and proteomic signatures, which are increasingly being reported as pre-symptomatic, diagnostic and prognostic of toxicity and disease. These advancements also have profound implications for toxicological evaluation and safety assessment of pharmaceuticals and environmental chemicals. An approach based primarily on human in vivo and high-throughput in vitro human cell-line data is a distinct possibility. This would transform current chemical safety assessment practice which operates in a human “data poor” to a human “data rich” environment. This could also lead to a seismic shift from the current animal-based to an animal-free chemical safety assessment paradigm. PMID:27493630

Training system for digital mammographic diagnoses of breast cancer

NASA Astrophysics Data System (ADS)

Thomaz, R. L.; Nirschl Crozara, M. G.; Patrocinio, A. C.

2013-03-01

As the technology evolves, the analog mammography systems are being replaced by digital systems. The digital system uses video monitors as the display of mammographic images instead of the previously used screen-film and negatoscope for analog images. The change in the way of visualizing mammographic images may require a different approach for training the health care professionals in diagnosing the breast cancer with digital mammography. Thus, this paper presents a computational approach to train the health care professionals providing a smooth transition between analog and digital technology also training to use the advantages of digital image processing tools to diagnose the breast cancer. This computational approach consists of a software where is possible to open, process and diagnose a full mammogram case from a database, which has the digital images of each of the mammographic views. The software communicates with a gold standard digital mammogram cases database. This database contains the digital images in Tagged Image File Format (TIFF) and the respective diagnoses according to BI-RADSTM, these files are read by software and shown to the user as needed. There are also some digital image processing tools that can be used to provide better visualization of each single image. The software was built based on a minimalist and a user-friendly interface concept that might help in the smooth transition. It also has an interface for inputting diagnoses from the professional being trained, providing a result feedback. This system has been already completed, but hasn't been applied to any professional training yet.

Integrated quantitative fractal polarimetric analysis of monolayer lung cancer cells

NASA Astrophysics Data System (ADS)

Shrestha, Suman; Zhang, Lin; Quang, Tri; Farrahi, Tannaz; Narayan, Chaya; Deshpande, Aditi; Na, Ying; Blinzler, Adam; Ma, Junyu; Liu, Bo; Giakos, George C.

2014-05-01

Digital diagnostic pathology has become one of the most valuable and convenient advancements in technology over the past years. It allows us to acquire, store and analyze pathological information from the images of histological and immunohistochemical glass slides which are scanned to create digital slides. In this study, efficient fractal, wavelet-based polarimetric techniques for histological analysis of monolayer lung cancer cells will be introduced and different monolayer cancer lines will be studied. The outcome of this study indicates that application of fractal, wavelet polarimetric principles towards the analysis of squamous carcinoma and adenocarcinoma cancer cell lines may be proved extremely useful in discriminating among healthy and lung cancer cells as well as differentiating among different lung cancer cells.

Image Acquisition and Quality in Digital Radiography.

PubMed

Alexander, Shannon

2016-09-01

Medical imaging has undergone dramatic changes and technological breakthroughs since the introduction of digital radiography. This article presents information on the development of digital radiography and types of digital radiography systems. Aspects of image quality and radiation exposure control are highlighted as well. In addition, the article includes related workplace changes and medicolegal considerations in the digital radiography environment. ©2016 American Society of Radiologic Technologists.

Securing Digital Images Integrity using Artificial Neural Networks

NASA Astrophysics Data System (ADS)

Hajji, Tarik; Itahriouan, Zakaria; Ouazzani Jamil, Mohammed

2018-05-01

Digital image signature is a technique used to protect the image integrity. The application of this technique can serve several areas of imaging applied to smart cities. The objective of this work is to propose two methods to protect digital image integrity. We present a description of two approaches using artificial neural networks (ANN) to digitally sign an image. The first one is “Direct Signature without learning” and the second is “Direct Signature with learning”. This paper presents the theory of proposed approaches and an experimental study to test their effectiveness.

Digital image processing: a primer for JVIR authors and readers: Part 3: Digital image editing.

PubMed

LaBerge, Jeanne M; Andriole, Katherine P

2003-12-01

This is the final installment of a three-part series on digital image processing intended to prepare authors for online submission of manuscripts. In the first two articles of the series, the fundamentals of digital image architecture were reviewed and methods of importing images to the computer desktop were described. In this article, techniques are presented for editing images in preparation for online submission. A step-by-step guide to basic editing with use of Adobe Photoshop is provided and the ethical implications of this activity are explored.

A mathematical model of neuro-fuzzy approximation in image classification

NASA Astrophysics Data System (ADS)

Gopalan, Sasi; Pinto, Linu; Sheela, C.; Arun Kumar M., N.

2016-06-01

Image digitization and explosion of World Wide Web has made traditional search for image, an inefficient method for retrieval of required grassland image data from large database. For a given input query image Content-Based Image Retrieval (CBIR) system retrieves the similar images from a large database. Advances in technology has increased the use of grassland image data in diverse areas such has agriculture, art galleries, education, industry etc. In all the above mentioned diverse areas it is necessary to retrieve grassland image data efficiently from a large database to perform an assigned task and to make a suitable decision. A CBIR system based on grassland image properties and it uses the aid of a feed-forward back propagation neural network for an effective image retrieval is proposed in this paper. Fuzzy Memberships plays an important role in the input space of the proposed system which leads to a combined neural fuzzy approximation in image classification. The CBIR system with mathematical model in the proposed work gives more clarity about fuzzy-neuro approximation and the convergence of the image features in a grassland image.

An improved contrast enhancement algorithm for infrared images based on adaptive double plateaus histogram equalization

NASA Astrophysics Data System (ADS)

Li, Shuo; Jin, Weiqi; Li, Li; Li, Yiyang

2018-05-01

Infrared thermal images can reflect the thermal-radiation distribution of a particular scene. However, the contrast of the infrared images is usually low. Hence, it is generally necessary to enhance the contrast of infrared images in advance to facilitate subsequent recognition and analysis. Based on the adaptive double plateaus histogram equalization, this paper presents an improved contrast enhancement algorithm for infrared thermal images. In the proposed algorithm, the normalized coefficient of variation of the histogram, which characterizes the level of contrast enhancement, is introduced as feedback information to adjust the upper and lower plateau thresholds. The experiments on actual infrared images show that compared to the three typical contrast-enhancement algorithms, the proposed algorithm has better scene adaptability and yields better contrast-enhancement results for infrared images with more dark areas or a higher dynamic range. Hence, it has high application value in contrast enhancement, dynamic range compression, and digital detail enhancement for infrared thermal images.

Digital processing of radiographic images for print publication.

PubMed

Cockerill, James W

2002-01-01

Digital imaging of X-rays yields high quality, evenly exposed negatives and prints. This article outlines the method used, materials and methods of this technique and discusses the advantages of digital radiographic images.

The wavelet/scalar quantization compression standard for digital fingerprint images

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, J.N.; Brislawn, C.M.

1994-04-01

A new digital image compression standard has been adopted by the US Federal Bureau of Investigation for use on digitized gray-scale fingerprint images. The algorithm is based on adaptive uniform scalar quantization of a discrete wavelet transform image decomposition and is referred to as the wavelet/scalar quantization standard. The standard produces archival quality images at compression ratios of around 20:1 and will allow the FBI to replace their current database of paper fingerprint cards with digital imagery.

Astronomers Find Elusive Planets in Decade-Old Hubble Data

NASA Image and Video Library

2017-12-08

NASA image release Oct. 6, 2011 This is an image of the star HR 8799 taken by Hubble's Near Infrared Camera and Multi-Object Spectrometer (NICMOS) in 1998. A mask within the camera (coronagraph) blocks most of the light from the star. In addition, software has been used to digitally subtract more starlight. Nevertheless, scattered light from HR 8799 dominates the image, obscuring the faint planets. Object Name: HR 8799 Image Type: Astronomical Credit: NASA, ESA, and R. Soummer (STScI) To read more go to: www.nasa.gov/mission_pages/hubble/science/elusive-planets... NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Method for indexing and retrieving manufacturing-specific digital imagery based on image content

DOEpatents

Ferrell, Regina K.; Karnowski, Thomas P.; Tobin, Jr., Kenneth W.

2004-06-15

A method for indexing and retrieving manufacturing-specific digital images based on image content comprises three steps. First, at least one feature vector can be extracted from a manufacturing-specific digital image stored in an image database. In particular, each extracted feature vector corresponds to a particular characteristic of the manufacturing-specific digital image, for instance, a digital image modality and overall characteristic, a substrate/background characteristic, and an anomaly/defect characteristic. Notably, the extracting step includes generating a defect mask using a detection process. Second, using an unsupervised clustering method, each extracted feature vector can be indexed in a hierarchical search tree. Third, a manufacturing-specific digital image associated with a feature vector stored in the hierarchicial search tree can be retrieved, wherein the manufacturing-specific digital image has image content comparably related to the image content of the query image. More particularly, can include two data reductions, the first performed based upon a query vector extracted from a query image. Subsequently, a user can select relevant images resulting from the first data reduction. From the selection, a prototype vector can be calculated, from which a second-level data reduction can be performed. The second-level data reduction can result in a subset of feature vectors comparable to the prototype vector, and further comparable to the query vector. An additional fourth step can include managing the hierarchical search tree by substituting a vector average for several redundant feature vectors encapsulated by nodes in the hierarchical search tree.

Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis.

PubMed

Isse, K; Lesniak, A; Grama, K; Roysam, B; Minervini, M I; Demetris, A J

2012-01-01

Conventional histopathology is the gold standard for allograft monitoring, but its value proposition is increasingly questioned. "-Omics" analysis of tissues, peripheral blood and fluids and targeted serologic studies provide mechanistic insights into allograft injury not currently provided by conventional histology. Microscopic biopsy analysis, however, provides valuable and unique information: (a) spatial-temporal relationships; (b) rare events/cells; (c) complex structural context; and (d) integration into a "systems" model. Nevertheless, except for immunostaining, no transformative advancements have "modernized" routine microscopy in over 100 years. Pathologists now team with hardware and software engineers to exploit remarkable developments in digital imaging, nanoparticle multiplex staining, and computational image analysis software to bridge the traditional histology-global "-omic" analyses gap. Included are side-by-side comparisons, objective biopsy finding quantification, multiplexing, automated image analysis, and electronic data and resource sharing. Current utilization for teaching, quality assurance, conferencing, consultations, research and clinical trials is evolving toward implementation for low-volume, high-complexity clinical services like transplantation pathology. Cost, complexities of implementation, fluid/evolving standards, and unsettled medical/legal and regulatory issues remain as challenges. Regardless, challenges will be overcome and these technologies will enable transplant pathologists to increase information extraction from tissue specimens and contribute to cross-platform biomarker discovery for improved outcomes. ©Copyright 2011 The American Society of Transplantation and the American Society of Transplant Surgeons.

Integration of digital signal processing technologies with pulsed electron paramagnetic resonance imaging

PubMed Central

Pursley, Randall H.; Salem, Ghadi; Devasahayam, Nallathamby; Subramanian, Sankaran; Koscielniak, Janusz; Krishna, Murali C.; Pohida, Thomas J.

2006-01-01

The integration of modern data acquisition and digital signal processing (DSP) technologies with Fourier transform electron paramagnetic resonance (FT-EPR) imaging at radiofrequencies (RF) is described. The FT-EPR system operates at a Larmor frequency (Lf) of 300 MHz to facilitate in vivo studies. This relatively low frequency Lf, in conjunction with our ~10 MHz signal bandwidth, enables the use of direct free induction decay time-locked subsampling (TLSS). This particular technique provides advantages by eliminating the traditional analog intermediate frequency downconversion stage along with the corresponding noise sources. TLSS also results in manageable sample rates that facilitate the design of DSP-based data acquisition and image processing platforms. More specifically, we utilize a high-speed field programmable gate array (FPGA) and a DSP processor to perform advanced real-time signal and image processing. The migration to a DSP-based configuration offers the benefits of improved EPR system performance, as well as increased adaptability to various EPR system configurations (i.e., software configurable systems instead of hardware reconfigurations). The required modifications to the FT-EPR system design are described, with focus on the addition of DSP technologies including the application-specific hardware, software, and firmware developed for the FPGA and DSP processor. The first results of using real-time DSP technologies in conjunction with direct detection bandpass sampling to implement EPR imaging at RF frequencies are presented. PMID:16243552

The application of digital image plane holography technology to identify Chinese herbal medicine

NASA Astrophysics Data System (ADS)

Wang, Huaying; Guo, Zhongjia; Liao, Wei; Zhang, Zhihui

2012-03-01

In this paper, the imaging technology of digital image plane holography to identify the Chinese herbal medicine is studied. The optical experiment system of digital image plane holography which is the special case of pre-magnification digital holography was built. In the record system, one is an object light by using plane waves which illuminates the object, and the other one is recording hologram by using spherical light wave as reference light. There is a Micro objective lens behind the object. The second phase factor which caus ed by the Micro objective lens can be eliminated by choosing the proper position of the reference point source when digital image plane holography is recorded by spherical light. In this experiment, we use the Lygodium cells and Onion cells as the object. The experiment results with Lygodium cells and Onion cells show that digital image plane holography avoid the process of finding recording distance by using auto-focusing approach, and the phase information of the object can be reconstructed more accurately. The digital image plane holography is applied to the microscopic imaging of cells more effectively, and it is suit to apply for the identify of Chinese Herbal Medicine. And it promotes the application of digital holographic in practice.

Morphogenic designer--an efficient tool to digitally design tooth forms.

PubMed

Hajtó, J; Marinescu, C; Silva, N R F A

2014-01-01

Different digital software tools are available today for the purpose of designing anatomically correct anterior and posterior restorations. The current concepts present weaknesses, which can be potentially addressed by more advanced modeling tools, such as the ones already available in professional CAD (Computer Aided Design) graphical software. This study describes the morphogenic designer (MGD) as an efficient and easy method for digitally designing tooth forms for the anterior and posterior dentition. Anterior and posterior tooth forms were selected from a collection of digitalized natural teeth and subjectively assessed as "average". The models in the form of STL files were filtered, cleaned, idealized, and re-meshed to match the specifications of the software used. The shapes were then imported as wavefront ".obj" model into Modo 701, software built for modeling, texturing, visualization, and animation. In order to create a parametric design system, intentional interactive deformations were performed on the average tooth shapes and then further defined as morph targets. By combining various such parameters, several tooth shapes were formed virtually and their images presented. MGD proved to be a versatile and powerful tool for the purpose of esthetic and functional digital crown designs.

Clinical performance of a prototype flat-panel digital detector for general radiography

NASA Astrophysics Data System (ADS)

Huda, Walter; Scalzetti, Ernest M.; Roskopf, Marsha L.; Geiger, Robert

2001-08-01

Digital radiographs obtained using a prototype Digital Radiography System (Stingray) were compared with those obtained using conventional screen-film. Forty adult volunteers each had two identical radiographs taken at the same level of radiation exposure, one using screen-film and the other the digital detector. Each digital image was processed by hand to ensure that the printed quality was optimal. Ten radiologists compared the diagnostic image quality of the digital images with the corresponding film radiographs using a seven point ranking scheme.

42 CFR 37.44 - Approval of radiographic facilities that use digital radiography systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... effective management, safety, and proper performance of chest image acquisition, digitization, processing... digital chest radiographs by submitting to NIOSH digital radiographic image files of a test object (e.g... radiographic image files from six or more sample chest radiographs that are of acceptable quality to one or...

The Engineer Topographic Laboratories /ETL/ hybrid optical/digital image processor

NASA Astrophysics Data System (ADS)

Benton, J. R.; Corbett, F.; Tuft, R.

1980-01-01

An optical-digital processor for generalized image enhancement and filtering is described. The optical subsystem is a two-PROM Fourier filter processor. Input imagery is isolated, scaled, and imaged onto the first PROM; this input plane acts like a liquid gate and serves as an incoherent-to-coherent converter. The image is transformed onto a second PROM which also serves as a filter medium; filters are written onto the second PROM with a laser scanner in real time. A solid state CCTV camera records the filtered image, which is then digitized and stored in a digital image processor. The operator can then manipulate the filtered image using the gray scale and color remapping capabilities of the video processor as well as the digital processing capabilities of the minicomputer.

15 CFR 786.2 - Recordkeeping.

Code of Federal Regulations, 2012 CFR

2012-01-01

... recognized as complete words or numbers. (iv) The system must preserve the initial image (including both... the system. (3) Requirements applicable to a system based on digital images. For systems based on the storage of digital images, the system must provide accessibility to any digital image in the system. The...

15 CFR 786.2 - Recordkeeping.

Code of Federal Regulations, 2011 CFR

2011-01-01

... recognized as complete words or numbers. (iv) The system must preserve the initial image (including both... the system. (3) Requirements applicable to a system based on digital images. For systems based on the storage of digital images, the system must provide accessibility to any digital image in the system. The...

15 CFR 786.2 - Recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-01-01

... recognized as complete words or numbers. (iv) The system must preserve the initial image (including both... the system. (3) Requirements applicable to a system based on digital images. For systems based on the storage of digital images, the system must provide accessibility to any digital image in the system. The...

15 CFR 786.2 - Recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-01-01

... recognized as complete words or numbers. (iv) The system must preserve the initial image (including both... the system. (3) Requirements applicable to a system based on digital images. For systems based on the storage of digital images, the system must provide accessibility to any digital image in the system. The...

15 CFR 786.2 - Recordkeeping.

Code of Federal Regulations, 2013 CFR

2013-01-01

... recognized as complete words or numbers. (iv) The system must preserve the initial image (including both... the system. (3) Requirements applicable to a system based on digital images. For systems based on the storage of digital images, the system must provide accessibility to any digital image in the system. The...

28 CFR 75.6 - Statement describing location of books and records.

Code of Federal Regulations, 2011 CFR

2011-07-01

...- or computer-manipulated image, digital image, or picture, or other matter (including but not limited... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital image, picture, or other matter to affix the statement. In this paragraph, the term “copy” includes...

Laser Looking at Earth

NASA Technical Reports Server (NTRS)

1999-01-01

TerraPoint (TM) LLC is a company that combines the technologies developed at NASA's Goddard Space Flight Center (GSFC) and the Houston Advanced Research Center (HARC) with the concept of topographic real estate imaging. TerraPoint provides its customers with digital, topographical data generated by laser technology rather than commonly used microwave (radar) and photographic technologies. This product's technology merges Goddard's and HARC's laser ranging, global positioning systems, and mapping software into a miniaturized package that can be mounted in a light aircraft.

Advances in Parallel Computing and Databases for Digital Pathology in Cancer Research

DTIC Science & Technology

2016-11-13

these technologies and how we have used them in the past. We are interested in learning more about the needs of clinical pathologists as we continue to...such as image processing and correlation. Further, High Performance Computing (HPC) paradigms such as the Message Passing Interface (MPI) have been...Defense for Research and Engineering. such as pMatlab [4], or bcMPI [5] can significantly reduce the need for deep knowledge of parallel computing. In

Handwritten mathematical symbols dataset

PubMed Central

Chajri, Yassine; Bouikhalene, Belaid

2016-01-01

Due to the technological advances in recent years, paper scientific documents are used less and less. Thus, the trend in the scientific community to use digital documents has increased considerably. Among these documents, there are scientific documents and more specifically mathematics documents. In this context, we present our own dataset of handwritten mathematical symbols composed of 10,379 images. This dataset gathers Arabic characters, Latin characters, Arabic numerals, Latin numerals, arithmetic operators, set-symbols, comparison symbols, delimiters, etc. PMID:27006975

Creating Orthographically Rectified Satellite Multi-Spectral Imagery with High Resolution Digital Elevation Model from LiDAR: A Tutorial

DTIC Science & Technology

2014-08-15

challenges. ERDC develops innovative solutions in civil and military engineering, geospatial sciences, water resources, and environmental sciences for...GRL TR-14-1 iv Abstract Orthoimages are used to produce image- map products for navigation and planning, and serve as source data for advanced...resulting mosaic covers a wider area and contains less visible seams, which makes the map easier to understand. RPC replace the actual sensor model while

Using Digital Globes to Explore the Deep Sea and Advance Public Literacy in Earth System Science

ERIC Educational Resources Information Center

Beaulieu, Stace E.; Emery, Emery; Brickley, Annette; Spargo, Abbey; Patterson, Kathleen; Joyce, Katherine; Silva, Tim; Madin, Katherine

2015-01-01

Digital globes are new technologies increasingly used in informal and formal education to display global datasets and show connections among Earth systems. But how effective are digital globes in advancing public literacy in Earth system science? We addressed this question by developing new content for digital globes with the intent to educate and…

Reproducible Operating Margins on a 72800-Device Digital Superconducting Chip (Open Access)

DTIC Science & Technology

2015-10-28

superconductor digital logic. Keywords: flux trapping, yield, digital Superconductor digital technology offers fundamental advantages over conventional...trapping in the superconductor films can degrade or preclude correct circuit operation. Scaling superconductor technology is now possible due to recent...advances in circuit design embodied in reciprocal quantum logic (RQL) [2, 3] and recent advances in superconductor integrated circuit fabrication, which

Intelligent Image Analysis for Image-Guided Laser Hair Removal and Skin Therapy

NASA Technical Reports Server (NTRS)

Walker, Brian; Lu, Thomas; Chao, Tien-Hsin

2012-01-01

We present the development of advanced automatic target recognition (ATR) algorithms for the hair follicles identification in digital skin images to accurately direct the laser beam to remove the hair. The ATR system first performs a wavelet filtering to enhance the contrast of the hair features in the image. The system then extracts the unique features of the targets and sends the features to an Adaboost based classifier for training and recognition operations. The ATR system automatically classifies the hair, moles, or other skin lesion and provides the accurate coordinates of the intended hair follicle locations. The coordinates can be used to guide a scanning laser to focus energy only on the hair follicles. The intended benefit would be to protect the skin from unwanted laser exposure and to provide more effective skin therapy.

Benefit from NASA

NASA Image and Video Library

2001-09-01

The high-tech art of digital signal processing (DSP) was pioneered at NASA's Jet Propulsion Laboratory (JPL) in the mid-1960s for use in the Apollo Lunar Landing Program. Designed to computer enhance pictures of the Moon, this technology became the basis for the Landsat Earth resources satellites and subsequently has been incorporated into a broad range of Earthbound medical and diagnostic tools. DSP is employed in advanced body imaging techniques including Computer-Aided Tomography, also known as CT and CATScan, and Magnetic Resonance Imaging (MRI). CT images are collected by irradiating a thin slice of the body with a fan-shaped x-ray beam from a number of directions around the body's perimeter. A tomographic (slice-like) picture is reconstructed from these multiple views by a computer. MRI employs a magnetic field and radio waves, rather than x-rays, to create images.

Diagnostic imaging applications; Proceedings of the Meeting, Amsterdam, Netherlands, October 8, 9, 1984

NASA Technical Reports Server (NTRS)

Beckenbach, E. S. (Editor)

1984-01-01

It is more important than ever that engineers have an understanding of the future needs of clinical and research medicine, and that physicians know somthing about probable future developments in instrumentation capabilities. Only by maintaining such a dialog can the most effective application of technological advances to medicine be achieved. This workshop attempted to provide this kind of information transfer in the limited field of diagnostic imaging. Biomedical research at the Jet Propulsion Laboratory is discussed, taking into account imaging results from space exploration missions, as well as biomedical research tasks based in these technologies. Attention is also given to current and future indications for magnetic resonance in medicine, high speed quantitative digital microscopy, computer processing of radiographic images, computed tomography and its modern applications, position emission tomography, and developments related to medical ultrasound.

Liquid Crystals, PIV and IR-Photography in Selected Technical and Biomedical Applications

NASA Astrophysics Data System (ADS)

Stasiek, Jan; Jewartowski, Marcin

2017-10-01

Thermochromic liquid crystals (TLC), Particle Image Velocimetry (PIV), Infrared Imaging Themography (IR) and True-Colour Digital Image Processing (TDIP) have been successfully used in non-intrusive technical, industrial and biomedical studies and applications. These four tools (based on the desktop computers) have come together during the past two decades to produce a powerful advanced experimental technique as a judgment of quality of information that cannot be obtained from any other imaging procedure. The brief summary of the history of this technique is reviewed, principal methods and tools are described and some examples are presented. With this objective, a new experimental technique have been developed and applied to the study of heat and mass transfer and for biomedical diagnosis. Automated evaluation allows determining the heat and flow visualisation and locate the area of suspicious tissue of human body.

Satellite land remote sensing advancements for the eighties; Proceedings of the Eighth Pecora Symposium, Sioux Falls, SD, October 4-7, 1983

NASA Technical Reports Server (NTRS)

1984-01-01

Among the topics discussed are NASA's land remote sensing plans for the 1980s, the evolution of Landsat 4 and the performance of its sensors, the Landsat 4 thematic mapper image processing system radiometric and geometric characteristics, data quality, image data radiometric analysis and spectral/stratigraphic analysis, and thematic mapper agricultural, forest resource and geological applications. Also covered are geologic applications of side-looking airborne radar, digital image processing, the large format camera, the RADARSAT program, the SPOT 1 system's program status, distribution plans, and simulation program, Space Shuttle multispectral linear array studies of the optical and biological properties of terrestrial land cover, orbital surveys of solar-stimulated luminescence, the Space Shuttle imaging radar research facility, and Space Shuttle-based polar ice sounding altimetry.

Computational imaging of sperm locomotion.

PubMed

Daloglu, Mustafa Ugur; Ozcan, Aydogan

2017-08-01

Not only essential for scientific research, but also in the analysis of male fertility and for animal husbandry, sperm tracking and characterization techniques have been greatly benefiting from computational imaging. Digital image sensors, in combination with optical microscopy tools and powerful computers, have enabled the use of advanced detection and tracking algorithms that automatically map sperm trajectories and calculate various motility parameters across large data sets. Computational techniques are driving the field even further, facilitating the development of unconventional sperm imaging and tracking methods that do not rely on standard optical microscopes and objective lenses, which limit the field of view and volume of the semen sample that can be imaged. As an example, a holographic on-chip sperm imaging platform, only composed of a light-emitting diode and an opto-electronic image sensor, has emerged as a high-throughput, low-cost and portable alternative to lens-based traditional sperm imaging and tracking methods. In this approach, the sample is placed very close to the image sensor chip, which captures lensfree holograms generated by the interference of the background illumination with the light scattered from sperm cells. These holographic patterns are then digitally processed to extract both the amplitude and phase information of the spermatozoa, effectively replacing the microscope objective lens with computation. This platform has further enabled high-throughput 3D imaging of spermatozoa with submicron 3D positioning accuracy in large sample volumes, revealing various rare locomotion patterns. We believe that computational chip-scale sperm imaging and 3D tracking techniques will find numerous opportunities in both sperm related research and commercial applications. © The Authors 2017. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Remote histology learning from static versus dynamic microscopic images.

PubMed

Mione, Sylvia; Valcke, Martin; Cornelissen, Maria

2016-05-06

Histology is the study of microscopic structures in normal tissue sections. Curriculum redesign in medicine has led to a decrease in the use of optical microscopes during practical classes. Other imaging solutions have been implemented to facilitate remote learning. With advancements in imaging technologies, learning material can now be digitized. Digitized microscopy images can be presented in either a static or dynamic format. This study of remote histology education identifies whether dynamic pictures are superior to static images for the acquisition of histological knowledge. Test results of two cohorts of second-year Bachelor in Medicine students at Ghent University were analyzed in two consecutive academic years: Cohort 1 (n = 190) and Cohort 2 (n = 174). Students in Cohort 1 worked with static images whereas students in Cohort 2 were presented with dynamic images. ANCOVA was applied to study differences in microscopy performance scores between the two cohorts, taking into account any possible initial differences in prior knowledge. The results show that practical histology scores are significantly higher with dynamic images as compared to static images (F (1,361) = 15.14, P < 0.01), regardless of student's gender and performance level. Several reasons for this finding can be explained in accordance with cognitivist learning theory. Since the findings suggest that knowledge construction with dynamic pictures is stronger as compared to static images, dynamic images should be introduced in a remote setting for microscopy education. Further implementation within a larger electronic learning management system needs to be explored in future research. Anat Sci Educ 9: 222-230. © 2015 American Association of Anatomists. © 2015 American Association of Anatomists.

More than meets the eye: digital fraud in dentistry.

PubMed

Rao, S A; Singh, N; Kumar, R; Thomas, A M

2010-01-01

Digital photographs play a substantial role in the presentation and validation of clinical cases for documentation and research purposes in esthetically oriented professions such as dentistry. The introduction of sophisticated cameras and "easy to use" computer software readily available on today's market has enabled digital fraud to emerge as a common and widely used practice. Hence, it is essential that both dentists and editorial circles are aware and cautious with regard to the possibility of digital fraud. A set of 10 routine "pre-" and "post" treatment dental procedure photographs were taken and randomly manipulated using standard desktop software. A team of 10 dental professionals were selected and each one of them was individually requested to review and evaluate the authenticity of the photographs. An assessment of expert opinion revealed an overall sensitivity of 60% and a sensitivity of 15% in correctly identifying a manipulated photograph, which is considered low. Furthermore, there was poor interobserver agreement. Advanced technology that is easily available has resulted in adept digital fraud that is difficult to detect. There is a need for awareness among both dental practitioners and the editorial circle regarding misrepresentation due to image manipulation. It is therefore necessary to follow a skeptical approach in the assessment of digitalized photos used in research and as a part of clinical dentistry.

Confocal mosaicing microscopy of human skin ex vivo: spectral analysis for digital staining to simulate histology-like appearance

PubMed Central

Bini, Jason; Spain, James; Nehal, Kishwer; Hazelwood, Vikki; DiMarzio, Charles; Rajadhyaksha, Milind

2011-01-01

Confocal mosaicing microscopy enables rapid imaging of large areas of fresh tissue, without the processing that is necessary for conventional histology. Mosaicing may offer a means to perform rapid histology at the bedside. A possible barrier toward clinical acceptance is that the mosaics are based on a single mode of grayscale contrast and appear black and white, whereas histology is based on two stains (hematoxylin for nuclei, eosin for cellular cytoplasm and dermis) and appears purple and pink. Toward addressing this barrier, we report advances in digital staining: fluorescence mosaics that show only nuclei, are digitally stained purple and overlaid on reflectance mosaics, which show only cellular cytoplasm and dermis, and are digitally stained pink. With digital staining, the appearance of confocal mosaics mimics the appearance of histology. Using multispectral analysis and color matching functions, red, green, and blue (RGB) components of hematoxylin and eosin stains in tissue were determined. The resulting RGB components were then applied in a linear algorithm to transform fluorescence and reflectance contrast in confocal mosaics to the absorbance contrast seen in pathology. Optimization of staining with acridine orange showed improved quality of digitally stained mosaics, with good correlation to the corresponding histology. PMID:21806269

Global manipulation of digital images can lead to variation in cytological diagnosis

PubMed Central

Prasad, H; Wanjari, Sangeeta; Parwani, Rajkumar

2011-01-01

Background: With the adoption of a completely electronic workflow by several journals and the advent of telepathology, digital imaging has become an integral part of every scientific research. However, manipulating digital images is very easy, and it can lead to misinterpretations. Aim: To analyse the impact of manipulating digital images on their diagnosis. Design: Digital images were obtained from Papanicolaou-stained smears of dysplastic and normal oral epithelium. They were manipulated using GNU Image Manipulation Program (GIMP) to alter their brightness and contrast and color levels. A Power Point presentation composed of slides of these manipulated images along with the unaltered originals arranged randomly was created. The presentation was shown to five observers individually who rated the images as normal, mild, moderate or severe dysplasia. Weighted κ statistics was used to measure and assess the levels of agreement between observers. Results: Levels of agreement between manipulated images and original images varied greatly among observers. Variation in diagnosis was in the form of overdiagnosis or under-diagnosis, usually by one grade. Conclusion: Global manipulations of digital images of cytological slides can significantly affect their interpretation. Such manipulations should therefore be kept to a minimum, and avoided wherever possible. PMID:21572507

Global manipulation of digital images can lead to variation in cytological diagnosis.

PubMed

Prasad, H; Wanjari, Sangeeta; Parwani, Rajkumar

2011-03-31

With the adoption of a completely electronic workflow by several journals and the advent of telepathology, digital imaging has become an integral part of every scientific research. However, manipulating digital images is very easy, and it can lead to misinterpretations. To analyse the impact of manipulating digital images on their diagnosis. Digital images were obtained from Papanicolaou-stained smears of dysplastic and normal oral epithelium. They were manipulated using GNU Image Manipulation Program (GIMP) to alter their brightness and contrast and color levels. A Power Point presentation composed of slides of these manipulated images along with the unaltered originals arranged randomly was created. The presentation was shown to five observers individually who rated the images as normal, mild, moderate or severe dysplasia. Weighted κ statistics was used to measure and assess the levels of agreement between observers. Levels of agreement between manipulated images and original images varied greatly among observers. Variation in diagnosis was in the form of overdiagnosis or under-diagnosis, usually by one grade. Global manipulations of digital images of cytological slides can significantly affect their interpretation. Such manipulations should therefore be kept to a minimum, and avoided wherever possible.

Integration Of Digital Methodologies (Field, Processing, and Presentation) In A Combined Sedimentology/Stratigraphy and Structure Course

NASA Astrophysics Data System (ADS)

Malinconico, L. L., Jr.; Sunderlin, D.; Liew, C. W.

2015-12-01

Over the course of the last three years we have designed, developed and refined two Apps for the iPad. GeoFieldBook and StratLogger allow for the real-time display of spatial (structural) and temporal (stratigraphic) field data as well as very easy in-field navigation. Field techniques and methods for data acquisition and mapping in the field have dramatically advanced and simplified how we collect and analyze data while in the field. The Apps are not geologic mapping programs, but rather a way of bypassing the analog field book step to acquire digital data directly that can then be used in various analysis programs (GIS, Google Earth, Stereonet, spreadsheet and drawing programs). We now complete all of our fieldwork digitally. GeoFieldBook can be used to collect structural and other field observations. Each record includes location/date/time information, orientation measurements, formation names, text observations and photos taken with the tablet camera. Records are customizable, so users can add fields of their own choosing. Data are displayed on an image base in real time with oriented structural symbols. The image base is also used for in-field navigation. In StratLogger, the user records bed thickness, lithofacies, biofacies, and contact data in preset and modifiable fields. Each bed/unit record may also be photographed and geo-referenced. As each record is collected, a column diagram of the stratigraphic sequence is built in real time, complete with lithology color, lithology texture, and fossil symbols. The recorded data from any measured stratigraphic sequence can be exported as both the live-drawn column image and as a .csv formatted file for use in spreadsheet or other applications. Common to both Apps is the ability to export the data (via .csv files), photographs and maps or stratigraphic columns (images). Since the data are digital they are easily imported into various processing programs (for example for stereoplot analysis). Requiring that all maps, stratigraphic columns and cross-sections be produced digitally continues our integration on the use of digital technologies throughout the curriculum. Initial evaluation suggests that students using the Apps more quickly progress towards synthesis and interpretation of the data as well as a deeper understanding of complex 4D field relationships.

Digital holographic image fusion for a larger size object using compressive sensing

NASA Astrophysics Data System (ADS)

Tian, Qiuhong; Yan, Liping; Chen, Benyong; Yao, Jiabao; Zhang, Shihua

2017-05-01

Digital holographic imaging fusion for a larger size object using compressive sensing is proposed. In this method, the high frequency component of the digital hologram under discrete wavelet transform is represented sparsely by using compressive sensing so that the data redundancy of digital holographic recording can be resolved validly, the low frequency component is retained totally to ensure the image quality, and multiple reconstructed images with different clear parts corresponding to a laser spot size are fused to realize the high quality reconstructed image of a larger size object. In addition, a filter combing high-pass and low-pass filters is designed to remove the zero-order term from a digital hologram effectively. The digital holographic experimental setup based on off-axis Fresnel digital holography was constructed. The feasible and comparative experiments were carried out. The fused image was evaluated by using the Tamura texture features. The experimental results demonstrated that the proposed method can improve the processing efficiency and visual characteristics of the fused image and enlarge the size of the measured object effectively.

[Development of an ophthalmological clinical information system for inpatient eye clinics].

PubMed

Kortüm, K U; Müller, M; Babenko, A; Kampik, A; Kreutzer, T C

2015-12-01

In times of increased digitalization in healthcare, departments of ophthalmology are faced with the challenge of introducing electronic clinical health records (EHR); however, specialized software for ophthalmology is not available with most major EHR sytems. The aim of this project was to create specific ophthalmological user interfaces for large inpatient eye care providers within a hospitalwide EHR. Additionally the integration of ophthalmic imaging systems, scheduling and surgical documentation should be achieved. The existing EHR i.s.h.med (Siemens, Germany) was modified using advanced business application programming (ABAP) language to create specific ophthalmological user interfaces for reproduction and moreover optimization of the clinical workflow. A user interface for documentation of ambulatory patients with eight tabs was designed. From June 2013 to October 2014 a total of 61,551 patient contact details were documented. For surgical documentation a separate user interface was set up. Digital clinical orders for documentation of registration and scheduling of operations user interfaces were also set up. A direct integration of ophthalmic imaging modalities could be established. An ophthalmologist-orientated EHR for outpatient and surgical documentation for inpatient clinics was created and successfully implemented. By incorporation of imaging procedures the foundation of future smart/big data analyses was created.

A Call to Action for Research in Digital Learning: Learning without Limits of Time, Place, Path, Pace…or Evidence

ERIC Educational Resources Information Center

Cavanaugh, Cathy; Sessums, Christopher; Drexler, Wendy

2015-01-01

This essay is a call for rethinking our approach to research in digital learning. It plots a path founded in social trends and advances in education. A brief review of these trends and advances is followed by discussion of what flattened research might look like at scale. Scaling research in digital learning is crucial to advancing understanding…

System for objective assessment of image differences in digital cinema

NASA Astrophysics Data System (ADS)

Fliegel, Karel; Krasula, Lukáš; Páta, Petr; Myslík, Jiří; Pecák, Josef; Jícha, Marek

2014-09-01

There is high demand for quick digitization and subsequent image restoration of archived film records. Digitization is very urgent in many cases because various invaluable pieces of cultural heritage are stored on aging media. Only selected records can be reconstructed perfectly using painstaking manual or semi-automatic procedures. This paper aims to answer the question what are the quality requirements on the restoration process in order to obtain acceptably close visual perception of the digitally restored film in comparison to the original analog film copy. This knowledge is very important to preserve the original artistic intention of the movie producers. Subjective experiment with artificially distorted images has been conducted in order to answer the question what is the visual impact of common image distortions in digital cinema. Typical color and contrast distortions were introduced and test images were presented to viewers using digital projector. Based on the outcome of this subjective evaluation a system for objective assessment of image distortions has been developed and its performance tested. The system utilizes calibrated digital single-lens reflex camera and subsequent analysis of suitable features of images captured from the projection screen. The evaluation of captured image data has been optimized in order to obtain predicted differences between the reference and distorted images while achieving high correlation with the results of subjective assessment. The system can be used to objectively determine the difference between analog film and digital cinema images on the projection screen.

Digital material laboratory: Considerations on high-porous volcanic rock

NASA Astrophysics Data System (ADS)

Saenger, Erik H.; Stöckhert, Ferdinand; Duda, Mandy; Fischer, Laura; Osorno, Maria; Steeb, Holger

2017-04-01

Digital material methodology combines modern microscopic imaging with advanced numerical simulations of the physical properties of materials. One goal is to complement physical laboratory investigations for a deeper understanding of relevant physical processes. Large-scale numerical modeling of elastic wave propagation directly from the microstructure of the porous material is integral to this technology. The parallelized finite-difference-based Stokes solver is suitable for the calculation of effective hydraulic parameters for low and high porous materials. Reticulite is formed in very high Hawaiian fire fountaining events. Hawaiian fire fountaining eruptions produce columns or fountains of lava, which can last for a few hours to days. Reticulite was originally thought to have formed from further expanded hot scoria foam. However, some researchers believe reticulite forms from magma that formed vesicles instantly, which expanded rapidly and uniformly to produce the polyhedral vesicle walls. These walls then ruptured and cooled rapidly. The (open) honeycomb network of bubbles is held together by glassy threads and forms a structure with a porosity higher than 80%. The fragile rock sample is difficult to characterize with classical experimental methods and we show how to determine porosity, effective elastic properties and Darcy permeability by using digital material methodology. A technical challenge will be to image with the CT technique the thin skin between the glassy threads visible on the microscopy image. A numerical challenge will be determination of effective material properties and viscous fluid effects on wave propagation in such a high porous material.

3D documenatation of the petalaindera: digital heritage preservation methods using 3D laser scanner and photogrammetry

NASA Astrophysics Data System (ADS)

Sharif, Harlina Md; Hazumi, Hazman; Hafizuddin Meli, Rafiq

2018-01-01

3D imaging technologies have undergone massive revolution in recent years. Despite this rapid development, documentation of 3D cultural assets in Malaysia is still very much reliant upon conventional techniques such as measured drawings and manual photogrammetry. There is very little progress towards exploring new methods or advanced technologies to convert 3D cultural assets into 3D visual representation and visualization models that are easily accessible for information sharing. In recent years, however, the advent of computer vision (CV) algorithms make it possible to reconstruct 3D geometry of objects by using image sequences from digital cameras, which are then processed by web services and freeware applications. This paper presents a completed stage of an exploratory study that investigates the potentials of using CV automated image-based open-source software and web services to reconstruct and replicate cultural assets. By selecting an intricate wooden boat, Petalaindera, this study attempts to evaluate the efficiency of CV systems and compare it with the application of 3D laser scanning, which is known for its accuracy, efficiency and high cost. The final aim of this study is to compare the visual accuracy of 3D models generated by CV system, and 3D models produced by 3D scanning and manual photogrammetry for an intricate subject such as the Petalaindera. The final objective is to explore cost-effective methods that could provide fundamental guidelines on the best practice approach for digital heritage in Malaysia.

42 CFR 37.51 - Interpreting and classifying chest radiographs-digital radiography systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... chest radiographic images provided for use with the Guidelines for the Use of the ILO International... standard digital images may be used for classifying digital chest images for pneumoconiosis. Modification of the appearance of the standard images using software tools is not permitted. (d) Viewing systems...

Integrating Digital Images into the Art and Art History Curriculum.

ERIC Educational Resources Information Center

Pitt, Sharon P.; Updike, Christina B.; Guthrie, Miriam E.

2002-01-01

Describes an Internet-based image database system connected to a flexible, in-class teaching and learning tool (the Madison Digital Image Database) developed at James Madison University to bring digital images to the arts and humanities classroom. Discusses content, copyright issues, ensuring system effectiveness, instructional impact, sharing the…

Review on the characteristics of radiation detectors for dosimetry and imaging

NASA Astrophysics Data System (ADS)

Seco, Joao; Clasie, Ben; Partridge, Mike

2014-10-01

The enormous advances in the understanding of human anatomy, physiology and pathology in recent decades have led to ever-improving methods of disease prevention, diagnosis and treatment. Many of these achievements have been enabled, at least in part, by advances in ionizing radiation detectors. Radiology has been transformed by the implementation of multi-slice CT and digital x-ray imaging systems, with silver halide films now largely obsolete for many applications. Nuclear medicine has benefited from more sensitive, faster and higher-resolution detectors delivering ever-higher SPECT and PET image quality. PET/MR systems have been enabled by the development of gamma ray detectors that can operate in high magnetic fields. These huge advances in imaging have enabled equally impressive steps forward in radiotherapy delivery accuracy, with 4DCT, PET and MRI routinely used in treatment planning and online image guidance provided by cone-beam CT. The challenge of ensuring safe, accurate and precise delivery of highly complex radiation fields has also both driven and benefited from advances in radiation detectors. Detector systems have been developed for the measurement of electron, intensity-modulated and modulated arc x-ray, proton and ion beams, and around brachytherapy sources based on a very wide range of technologies. The types of measurement performed are equally wide, encompassing commissioning and quality assurance, reference dosimetry, in vivo dosimetry and personal and environmental monitoring. In this article, we briefly introduce the general physical characteristics and properties that are commonly used to describe the behaviour and performance of both discrete and imaging detectors. The physical principles of operation of calorimeters; ionization and charge detectors; semiconductor, luminescent, scintillating and chemical detectors; and radiochromic and radiographic films are then reviewed and their principle applications discussed. Finally, a general discussion of the application of detectors for x-ray nuclear medicine and ion beam imaging and dosimetry is presented.

Multiframe digitization of x-ray (TV) images (abstract)

NASA Astrophysics Data System (ADS)

Karpenko, V. A.; Khil'chenko, A. D.; Lysenko, A. P.; Panchenko, V. E.

1989-07-01

The work in progress deals with the experimental search for a technique of digitizing x-ray TV images. The small volume of the buffer memory of the analog-to-digital (A/D) converter (ADC) we have previously used to detect TV signals made it necessary to digitize only one line at a time of the television raster and also to make use of gating to gain the video information contained in the whole frame. This paper is devoted to multiframe digitizing. The recorder of video signals comprises a broadband 8-bit A/D converter, a buffer memory having 128K words and a control circuit which forms a necessary sequence of advance pulses for the A/D converter and the memory relative to the input frame and line sync pulses (FSP and LSP). The device provides recording of video signals corresponding to one or a few frames following one after another, or to their fragments. The control circuit is responsible for the separation of the required fragment of the TV image. When loading the limit registers, the following input parameters of the control circuit are set: the skipping of a definite number of lines after the next FSP, the number of the lines of recording inside a fragment, the frequency of the information lines inside a fragment, the delay in the start of the ADC conversion relative to the arrival of the LSP, the length of the information section of a line, and the frequency of taking the readouts in a line. In addition, among the instructions given are the number of frames of recording and the frequency of their sequence. Thus, the A/D converter operates only inside a given fragment of the TV image. The information is introduced into the memory in sequence, fragment by fragment, without skipping and is then extracted as samples according to the addresses needed for representation in the required form, and processing. The video signal recorder governs the shortest time of the ADC conversion per point of 250 ns. As before, among the apparatus used were an image vidicon with luminophor conversion of x-radiation to light, and a single-crystal x-ray diffraction scheme necessary to form dynamic test objects from x-ray lines dispersed in space (the projections of the linear focus of an x-ray tube).

The use of digital images in pathology.

PubMed

Furness, P N

1997-11-01

Digital images are routinely used by the publishing industry, but most diagnostic pathologists are unfamiliar with the technology and its possibilities. This review aims to explain the basic principles of digital image acquisition, storage, manipulation and use, and the possibilities provided not only in research, but also in teaching and in routine diagnostic pathology. Images of natural objects are usually expressed digitally as 'bitmaps'--rectilinear arrays of small dots. The size of each dot can vary, but so can its information content in terms, for example, of colour, greyscale or opacity. Various file formats and compression algorithms are available. Video cameras connected to microscopes are familiar to most pathologists; video images can be converted directly to a digital form by a suitably equipped computer. Digital cameras and scanners are alternative acquisition tools of relevance to pathologists. Once acquired, a digital image can easily be subjected to the digital equivalent of any conventional darkroom manipulation and modern software allows much more flexibility, to such an extent that a new tool for scientific fraud has been created. For research, image enhancement and analysis is an increasingly powerful and affordable tool. Morphometric measurements are, after many predictions, at last beginning to be part of the toolkit of the diagnostic pathologist. In teaching, the potential to create dramatic yet informative presentations is demonstrated daily by the publishing industry; such methods are readily applicable to the classroom. The combination of digital images and the Internet raises many possibilities; for example, instead of seeking one expert diagnostic opinion, one could simultaneously seek the opinion of many, all around the globe. It is inevitable that in the coming years the use of digital images will spread from the laboratory to the medical curriculum and to the whole of diagnostic pathology.

Data mining and visualization of average images in a digital hand atlas

NASA Astrophysics Data System (ADS)

Zhang, Aifeng; Gertych, Arkadiusz; Liu, Brent J.; Huang, H. K.

2005-04-01

We have collected a digital hand atlas containing digitized left hand radiographs of normally developed children grouped accordingly by age, sex, and race. A set of features stored in a database reflecting patient's stage of skeletal development has been calculated by automatic image processing procedures. This paper addresses a new concept, "average" image in the digital hand atlas. The "average" reference image in the digital atlas is selected for each of the groups of normal developed children with the best representative skeletal maturity based on bony features. A data mining procedure was designed and applied to find the average image through average feature vector matching. It also provides a temporary solution for the missing feature problem through polynomial regression. As more cases are added to the digital hand atlas, it can grow to provide clinicians accurate reference images to aid the bone age assessment process.

Synthesis method from low-coherence digital holograms for improvement of image quality in holographic display.

PubMed

Mori, Yutaka; Nomura, Takanori

2013-06-01

In holographic displays, it is undesirable to observe the speckle noises with the reconstructed images. A method for improvement of reconstructed image quality by synthesizing low-coherence digital holograms is proposed. It is possible to obtain speckleless reconstruction of holograms due to low-coherence digital holography. An image sensor records low-coherence digital holograms, and the holograms are synthesized by computational calculation. Two approaches, the threshold-processing and the picking-a-peak methods, are proposed in order to reduce random noise of low-coherence digital holograms. The reconstructed image quality by the proposed methods is compared with the case of high-coherence digital holography. Quantitative evaluation is given to confirm the proposed methods. In addition, the visual evaluation by 15 people is also shown.

From Horse-Drawn Wagon to Hot Rod: The University of California's Digital Image Service Experience

ERIC Educational Resources Information Center

Burns, Maureen A.

2006-01-01

This article proposes that a viable approach archivists might consider to meet increasing demands for access to digital images with functional presentation tools is to develop a reciprocal partnership with a digital library. The University of California's experience with the federation of licensed and UC-owned digital image collections is…

Biomedical imaging and sensing using flatbed scanners.

PubMed

Göröcs, Zoltán; Ozcan, Aydogan

2014-09-07

In this Review, we provide an overview of flatbed scanner based biomedical imaging and sensing techniques. The extremely large imaging field-of-view (e.g., ~600-700 cm(2)) of these devices coupled with their cost-effectiveness provide unique opportunities for digital imaging of samples that are too large for regular optical microscopes, and for collection of large amounts of statistical data in various automated imaging or sensing tasks. Here we give a short introduction to the basic features of flatbed scanners also highlighting the key parameters for designing scientific experiments using these devices, followed by a discussion of some of the significant examples, where scanner-based systems were constructed to conduct various biomedical imaging and/or sensing experiments. Along with mobile phones and other emerging consumer electronics devices, flatbed scanners and their use in advanced imaging and sensing experiments might help us transform current practices of medicine, engineering and sciences through democratization of measurement science and empowerment of citizen scientists, science educators and researchers in resource limited settings.

Biomedical Imaging and Sensing using Flatbed Scanners

PubMed Central

Göröcs, Zoltán; Ozcan, Aydogan

2014-01-01

In this Review, we provide an overview of flatbed scanner based biomedical imaging and sensing techniques. The extremely large imaging field-of-view (e.g., ~600–700 cm2) of these devices coupled with their cost-effectiveness provide unique opportunities for digital imaging of samples that are too large for regular optical microscopes, and for collection of large amounts of statistical data in various automated imaging or sensing tasks. Here we give a short introduction to the basic features of flatbed scanners also highlighting the key parameters for designing scientific experiments using these devices, followed by a discussion of some of the significant examples, where scanner-based systems were constructed to conduct various biomedical imaging and/or sensing experiments. Along with mobile phones and other emerging consumer electronics devices, flatbed scanners and their use in advanced imaging and sensing experiments might help us transform current practices of medicine, engineering and sciences through democratization of measurement science and empowerment of citizen scientists, science educators and researchers in resource limited settings. PMID:24965011

The Image Data Resource: A Bioimage Data Integration and Publication Platform.

PubMed

Williams, Eleanor; Moore, Josh; Li, Simon W; Rustici, Gabriella; Tarkowska, Aleksandra; Chessel, Anatole; Leo, Simone; Antal, Bálint; Ferguson, Richard K; Sarkans, Ugis; Brazma, Alvis; Salas, Rafael E Carazo; Swedlow, Jason R

2017-08-01

Access to primary research data is vital for the advancement of science. To extend the data types supported by community repositories, we built a prototype Image Data Resource (IDR) that collects and integrates imaging data acquired across many different imaging modalities. IDR links data from several imaging modalities, including high-content screening, super-resolution and time-lapse microscopy, digital pathology, public genetic or chemical databases, and cell and tissue phenotypes expressed using controlled ontologies. Using this integration, IDR facilitates the analysis of gene networks and reveals functional interactions that are inaccessible to individual studies. To enable re-analysis, we also established a computational resource based on Jupyter notebooks that allows remote access to the entire IDR. IDR is also an open source platform that others can use to publish their own image data. Thus IDR provides both a novel on-line resource and a software infrastructure that promotes and extends publication and re-analysis of scientific image data.

Geometric processing of digital images of the planets

NASA Technical Reports Server (NTRS)

Edwards, Kathleen

1987-01-01

New procedures and software have been developed for geometric transformation of images to support digital cartography of the planets. The procedures involve the correction of spacecraft camera orientation of each image with the use of ground control and the transformation of each image to a Sinusoidal Equal-Area map projection with an algorithm which allows the number of transformation calculations to vary as the distortion varies within the image. When the distortion is low in an area of an image, few transformation computations are required, and most pixels can be interpolated. When distortion is extreme, the location of each pixel is computed. Mosaics are made of these images and stored as digital databases. Completed Sinusoidal databases may be used for digital analysis and registration with other spatial data. They may also be reproduced as published image maps by digitally transforming them to appropriate map projections.

Final Technical Report for DE-SC0002014- July 29, 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramirez, NC

2011-07-29

The project titled “National Biorepository for Children’s and Women’s Cancer”. The funding received by the Biopathology Center (BPC) at the Research Institute at Nationwide Children’s Hospital was utilized to procure equipment and add resources to establish a national digital archive of tissues of children and women’s cancers to advance treatment and research. As planned in the proposal, the project allowed the BPC to procure two high-speed imaging robots and hire imaging technicians to scan a large collection of Children’s and Women’s cancer tissues. The BPC team focused on completed clinical trials, with some dating back nearly 30 years, conducted bymore » the Children’s Oncology Group (and its precursor groups) as well as the Gynecologic Oncology Group. A total of 139 clinical trials were imaged as part of the archive project allowing the team to generate 29, 488 images that are currently stored at the Ohio Supercomputer Center located in Columbus Ohio. The images are now integrated with the Virtual Imaging for Pathology, Education and Research (VIPER) application. The VIPER application allows the BPC to make the digital archive available via the Internet to approved researchers remotely eliminating the use of glass slides for this collection. The elimination of glass slides reduces costs associated with shipping, reduces breakage of glass slides and allows for the review of these cases quickly by experts on a standard desktop computer.« less

Soil Science in the Digital Age

ERIC Educational Resources Information Center

High, Vance; VanHorn, Laura

2012-01-01

With the pervasiveness of digital technology, elementary students almost instinctively begin inquiry-based instruction with a bias. Visual information from digital devices competes with elementary science inquiry. To counteract this effect, teachers can use advance organizers. The advance organizer is a tool or a mental learning aid to help…

The Use of Digital Narratives to Enhance Counseling and Psychotherapy

ERIC Educational Resources Information Center

Pillay, Yegan

2009-01-01

Technological advances have impinged on every aspect of contemporary phenomenological experiences, including counseling and psychotherapy. The author explores the intersection of narrative therapy, specifically the traditional memory book, with the advances in information technology in the formulation of the digital memory book. The digital memory…

A highly accurate wireless digital sun sensor based on profile detecting and detector multiplexing technologies

NASA Astrophysics Data System (ADS)

Wei, Minsong; Xing, Fei; You, Zheng

2017-01-01

The advancing growth of micro- and nano-satellites requires miniaturized sun sensors which could be conveniently applied in the attitude determination subsystem. In this work, a profile detecting technology based high accurate wireless digital sun sensor was proposed, which could transform a two-dimensional image into two-linear profile output so that it can realize a high update rate under a very low power consumption. A multiple spots recovery approach with an asymmetric mask pattern design principle was introduced to fit the multiplexing image detector method for accuracy improvement of the sun sensor within a large Field of View (FOV). A FOV determination principle based on the concept of FOV region was also proposed to facilitate both sub-FOV analysis and the whole FOV determination. A RF MCU, together with solar cells, was utilized to achieve the wireless and self-powered functionality. The prototype of the sun sensor is approximately 10 times lower in size and weight compared with the conventional digital sun sensor (DSS). Test results indicated that the accuracy of the prototype was 0.01° within a cone FOV of 100°. Such an autonomous DSS could be equipped flexibly on a micro- or nano-satellite, especially for highly accurate remote sensing applications.

Analysis of potential debris flow source areas on Mount Shasta, California, by using airborne and satellite remote sensing data

USGS Publications Warehouse

Crowley, J.K.; Hubbard, B.E.; Mars, J.C.

2003-01-01

Remote sensing data from NASA's Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) and the first spaceborne imaging spectrometer, Hyperion, show hydrothermally altered rocks mainly composed of natroalunite, kaolinite, cristobalite, and gypsum on both the Mount Shasta and Shastina cones. Field observations indicate that much of the visible altered rock consists of talus material derived from fractured rock zones within and adjacent to dacitic domes and nearby lava flows. Digital elevation data were utilized to distinguish steeply sloping altered bedrock from more gently sloping talus materials. Volume modeling based on the imagery and digital elevation data indicate that Mount Shasta drainage systems contain moderate volumes of altered rock, a result that is consistent with Mount Shasta's Holocene record of mostly small to moderate debris flows. Similar modeling for selected areas at Mount Rainier and Mount Adams, Washington, indicates larger altered rock volumes consistent with the occurrence of much larger Holocene debris flows at those volcanoes. The availability of digital elevation and spectral data from spaceborne sensors, such as Hyperion and the Advanced Spaceborne Thermal Emission and Reflectance Radiometer (ASTER), greatly expands opportunities for studying potential debris flow source characteristics at stratovolcanoes around the world. ?? 2003 Elsevier Inc. All rights reserved.