Science.gov

Sample records for advanced manufacturing center

  1. Ohio Advanced Energy Manufacturing Center

    SciTech Connect

    Kimberly Gibson; Mark Norfolk

    2012-07-30

    The program goal of the Ohio Advanced Energy Manufacturing Center (OAEMC) is to support advanced energy manufacturing and to create responsive manufacturing clusters that will support the production of advanced energy and energy-efficient products to help ensure the nation's energy and environmental security. This goal cuts across a number of existing industry segments critical to the nation's future. Many of the advanced energy businesses are starting to make the transition from technology development to commercial production. Historically, this transition from laboratory prototypes through initial production for early adopters to full production for mass markets has taken several years. Developing and implementing manufacturing technology to enable production at a price point the market will accept is a key step. Since these start-up operations are configured to advance the technology readiness of the core energy technology, they have neither the expertise nor the resources to address manufacturing readiness issues they encounter as the technology advances toward market entry. Given the economic realities of today's business environment, finding ways to accelerate this transition can make the difference between success and failure for a new product or business. The advanced energy industry touches a wide range of industry segments that are not accustomed to working together in complex supply chains to serve large markets such as automotive and construction. During its first three years, the Center has catalyzed the communication between companies and industry groups that serve the wide range of advanced energy markets. The Center has also found areas of common concern, and worked to help companies address these concerns on a segment or industry basis rather than having each company work to solve common problems individually. EWI worked with three industries through public-private partnerships to sew together disparate segments helping to promote overall industry

  2. National Center for Advanced Manufacturing Overview

    NASA Technical Reports Server (NTRS)

    Vickers, John H.

    2000-01-01

    This paper presents a general overview of the National Center for Advanced Manufacturing, with an emphasis on Aerospace Materials, Processes and Environmental Technology. The topics include: 1) Background; 2) Mission; 3) Technology Development Approach; 4) Space Transportation Significance; 5) Partnering; 6) NCAM MAF Project; 7) NASA & Calhoun Community College; 8) Educational Development; and 9) Intelligent Synthesis Environment. This paper is presented in viewgraph form.

  3. NASA's National Center for Advanced Manufacturing

    NASA Technical Reports Server (NTRS)

    Vickers, John

    2003-01-01

    NASA has designated the Principal Center Assignment to the Marshall Space Flight Center (MSFC) for implementation of the National Center for Advanced Manufacturing (NCAM). NCAM is NASA s leading resource for the aerospace manufacturing research, development, and innovation needs that are critical to the goals of the Agency. Through this initiative NCAM s people work together with government, industry, and academia to ensure the technology base and national infrastructure are available to develop innovative manufacturing technologies with broad application to NASA Enterprise programs, and U.S. industry. Educational enhancements are ever-present within the NCAM focus to promote research, to inspire participation and to support education and training in manufacturing. Many important accomplishments took place during 2002. Through NCAM, NASA was among five federal agencies involved in manufacturing research and development (R&D) to launch a major effort to exchange information and cooperate directly to enhance the payoffs from federal investments. The Government Agencies Technology Exchange in Manufacturing (GATE-M) is the only active effort to specifically and comprehensively address manufacturing R&D across the federal government. Participating agencies include the departments of Commerce (represented by the National Institute of Standards and Technology), Defense, and Energy, as well as the National Science Foundation and NASA. MSFC s ongoing partnership with the State of Louisiana, the University of New Orleans, and Lockheed Martin Corporation at the Michoud Assembly Facility (MAF) progressed significantly. Major capital investments were initiated for world-class equipment additions including a universal friction stir welding system, composite fiber placement machine, five-axis machining center, and ten-axis laser ultrasonic nondestructive test system. The NCAM consortium of five universities led by University of New Orleans with Mississippi State University

  4. National Center for Advanced Information Components Manufacturing. Program summary report, Volume 1

    SciTech Connect

    1996-10-01

    The National Center for Advanced Information Components Manufacturing focused on manufacturing research and development for flat panel displays, advanced lithography, microelectronics, and optoelectronics. This report provides an overview of the program, summaries of the technical projects, and key program accomplishments.

  5. National Center for Advanced Information Components Manufacturing. Program summary report, Volume II

    SciTech Connect

    1996-10-01

    The National Center for Advanced Information Components Manufacturing focused on manufacturing research and development for flat panel displays, advanced lithography, microelectronics, and optoelectronics. This report provides an overview of the program, program history, summaries of the technical projects, and key program accomplishments.

  6. Advanced Material Intelligent Processing Center: Next Generation Scalable Lean Manufacturing

    DTIC Science & Technology

    2012-09-04

    machines and have made significant advances to automated tape laying (ATL) and automated fiber placement (AFP) technologies. Companies are moving...beyond standard thermoplastic and thermoset prepregs and are looking at placing 00A prepregs as well as dry fabrics. Today. Automated Tape Laying (ATL...References [1] Michael N. Grimshaw, " Automated Tape Laying ." in ASM Handbook Vol. 21 Composites.. ASM International, 2001. [2] Obaid Younossi. Michael

  7. Advanced Manufacturing

    DTIC Science & Technology

    2002-01-01

    manufacturing will enable the mass customization of products and create new market opportunities in the commercial sector. Flexible manufacturing ...the mass customization of products and create new market opportunities in the commercial sector. One of the most promising flexible manufacturing ... manufacturing , increase efficiency and productivity. Research in leading edge technologies continues to promise exciting new manufacturing methods

  8. Advanced Manufacturing Technologies

    NASA Technical Reports Server (NTRS)

    Fikes, John

    2016-01-01

    Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

  9. Advanced Materials Intelligent Processing Center (AMIPC): Manufacturing for Multi-Functionality

    DTIC Science & Technology

    2005-12-31

    through the development and use of Resin Transfer Molding ( RTM ) and Vacuum Assisted Resin Transfer Molding ( VARTM ) to address processing, sensing, and...intelligent processing has been advanced through the development and use of Resin Transfer Molding VRTM) and Vacuum Assisted Resin Transfer Molding ( VARTm ...16 Task 4B: Process Developments: Resin Bleeding During VARTM Infusion ....................... _18 Task 5

  10. Advanced manufacturing: Technology diffusion

    SciTech Connect

    Tesar, A.

    1995-12-01

    In this paper we examine how manufacturing technology diffuses rom the developers of technology across national borders to those who do not have the capability or resources to develop advanced technology on their own. None of the wide variety of technology diffusion mechanisms discussed in this paper are new, yet the opportunities to apply these mechanisms are growing. A dramatic increase in technology diffusion occurred over the last decade. The two major trends which probably drive this increase are a worldwide inclination towards ``freer`` markets and diminishing isolation. Technology is most rapidly diffusing from the US In fact, the US is supplying technology for the rest of the world. The value of the technology supplied by the US more than doubled from 1985 to 1992 (see the Introduction for details). History shows us that technology diffusion is inevitable. It is the rates at which technologies diffuse to other countries which can vary considerably. Manufacturers in these countries are increasingly able to absorb technology. Their manufacturing efficiency is expected to progress as technology becomes increasingly available and utilized.

  11. Advanced Manufacture of Reflectors

    SciTech Connect

    Angel, Roger

    2014-12-17

    The main project objective has been to develop an advanced gravity sag method for molding large glass solar reflectors with either line or point focus, and with long or short focal length. The method involves taking standard sized squares of glass, 1.65 m x 1.65 m, and shaping them by gravity sag into precision steel molds. The method is designed for high volume manufacture when incorporated into a production line with separate pre-heating and cooling. The performance objectives for the self-supporting glass mirrors made by this project include mirror optical accuracy of 2 mrad root mean square (RMS), requiring surface slope errors less than 1 mrad rms, a target not met by current production of solar reflectors. Our objective also included development of new methods for rapidly shaping glass mirrors and coating them for higher reflectivity and soil resistance. Reflectivity of 95% for a glass mirror with anti-soil coating was targeted, compared to the present ~94% with no anti-soil coating. Our mirror cost objective is ~$20/m2 in 2020, a significant reduction compared to the present ~$35/m2 for solar trough mirrors produced for trough solar plants.

  12. Advanced Computing for Manufacturing.

    ERIC Educational Resources Information Center

    Erisman, Albert M.; Neves, Kenneth W.

    1987-01-01

    Discusses ways that supercomputers are being used in the manufacturing industry, including the design and production of airplanes and automobiles. Describes problems that need to be solved in the next few years for supercomputers to assume a major role in industry. (TW)

  13. Advances in Additive Manufacturing

    DTIC Science & Technology

    2016-07-14

    casting molds for traditional casting processes on the battlefield, and 3) the use of recycled polymeric materials as feedstock for 3-D printers ...nondestructive characterization technique allows for 3D imaging that readily captures defects and voids on the conditions that the attenuation, which is...of 3D -printed structures. Analysis examples will include quantification of tolerance differences between the designed and manufactured parts, void

  14. National Center for Manufacturing Sciences: Environmentally conscious manufacturing

    NASA Technical Reports Server (NTRS)

    Vinton, Clare

    1995-01-01

    The purpose of this presentation is to share the results and some of the thinking of the Environmentally Conscious Manufacturing - Strategic Initiative Group (ECM-SIG) at the National Center for Manufacturing Sciences (NCMS). NCMS is a consortium of more than 185 North American Manufacturing organizations comprised of about 75 percent for profit manufacturing companies and about 25 percent nonprofit organizations that support manufacturing activities. NCMS conducts collaborative R&D programs designed to improve global competitiveness of its members and other North American manufacturers to address common issues that are important to manufacturing industries. NCMS is an industry driven organization whose agenda is established by industry with input from appropriate government agencies.

  15. Advanced optical manufacturing digital integrated system

    NASA Astrophysics Data System (ADS)

    Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

    2012-10-01

    It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

  16. Recent manufacturing advances for spiral bevel gears

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.; Bill, Robert C.

    1991-01-01

    The U.S. Army Aviation Systems Command (AVSCOM), through the Propulsion Directorate at NASA Lewis Research Center, has recently sponsored projects to advance the manufacturing process for spiral bevel gears. This type of gear is a critical component in rotary-wing propulsion systems. Two successfully completed contracted projects are described. The first project addresses the automated inspection of spiral bevel gears through the use of coordinate measuring machines. The second project entails the computer-numerical-control (CNC) conversion of a spiral bevel gear grinding machine that is used for all aerospace spiral bevel gears. The results of these projects are described with regard to the savings effected in manufacturing time.

  17. Responding to Industry Demands: Advanced Technology Centers.

    ERIC Educational Resources Information Center

    Smith, Elizabeth Brient

    1991-01-01

    Discusses characteristics identified by the Center for Occupational Research and Development as indicative of fully functioning advanced technology centers, including the provision of training and retraining in such areas as design, manufacturing, materials science, and electro-optics; technology transfer; demonstration sites; needs assessment;…

  18. Advanced Technology Composite Fuselage - Manufacturing

    NASA Technical Reports Server (NTRS)

    Wilden, K. S.; Harris, C. G.; Flynn, B. W.; Gessel, M. G.; Scholz, D. B.; Stawski, S.; Winston, V.

    1997-01-01

    The goal of Boeing's Advanced Technology Composite Aircraft Structures (ATCAS) program is to develop the technology required for cost-and weight-efficient use of composite materials in transport fuselage structure. Carbon fiber reinforced epoxy was chosen for fuselage skins and stiffening elements, and for passenger and cargo floor structures. The automated fiber placement (AFP) process was selected for fabrication of stringer-stiffened and sandwich skin panels. Circumferential and window frames were braided and resin transfer molded (RTM'd). Pultrusion was selected for fabrication of floor beams and constant-section stiffening elements. Drape forming was chosen for stringers and other stiffening elements cocured to skin structures. Significant process development efforts included AFP, braiding, RTM, autoclave cure, and core blanket fabrication for both sandwich and stiffened-skin structure. Outer-mold-line and inner-mold-line tooling was developed for sandwich structures and stiffened-skin structure. The effect of design details, process control and tool design on repeatable, dimensionally stable, structure for low cost barrel assembly was assessed. Subcomponent panels representative of crown, keel, and side quadrant panels were fabricated to assess scale-up effects and manufacturing anomalies for full-scale structures. Manufacturing database including time studies, part quality, and manufacturing plans were generated to support the development of designs and analytical models to access cost, structural performance, and dimensional tolerance.

  19. Clean Energy Manufacturing Analysis Center (CEMAC)

    SciTech Connect

    2015-12-01

    The U.S. Department of Energy's Clean Energy Manufacturing Analysis Center (CEMAC) provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Policymakers and industry leaders seek CEMAC insights to inform choices to promote economic growth and the transition to a clean energy economy.

  20. Stitching Techniques Advance Optics Manufacturing

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Because NASA depends on the fabrication and testing of large, high-quality aspheric (nonspherical) optics for applications like the James Webb Space Telescope, it sought an improved method for measuring large aspheres. Through Small Business Innovation Research (SBIR) awards from Goddard Space Flight Center, QED Technologies, of Rochester, New York, upgraded and enhanced its stitching technology for aspheres. QED developed the SSI-A, which earned the company an R&D 100 award, and also developed a breakthrough machine tool called the aspheric stitching interferometer. The equipment is applied to advanced optics in telescopes, microscopes, cameras, medical scopes, binoculars, and photolithography."

  1. Advance Manufacturing Office FY 2017 Budget At-A-Glance

    SciTech Connect

    2016-03-01

    The Advanced Manufacturing Office (AMO) brings together manufacturers, research institutions, suppliers, and universities to investigate manufacturing processes, information, and materials technologies critical to advance domestic manufacturing of clean energy products, and to support energy productivity across the entire manufacturing sector.

  2. Manufacturing development of DC-10 advanced rudder

    NASA Technical Reports Server (NTRS)

    Cominsky, A.

    1979-01-01

    The design, manufacture, and ground test activities during development of production methods for an advanced composite rudder for the DC-10 transport aircraft are described. The advanced composite aft rudder is satisfactory for airline service and a cost saving in a full production manufacturing mode is anticipated.

  3. Manufacturing Technology Information Analysis Center: Knowledge Is Strength

    NASA Technical Reports Server (NTRS)

    Safar, Michal

    1992-01-01

    The Center's primary function is to facilitate technology transfer within DoD, other government agencies and industry. The DoD has recognized the importance of technology transfer, not only to support specific weapon system manufacture, but to strengthen the industrial base that sustains DoD. MTIAC uses an experienced technical staff of engineers and information specialists to acquire, analyze, and disseminate technical information. Besides ManTech project data, MTIAC collects manufacturing technology from other government agencies, commercial publications, proceedings, and various international sources. MTIAC has various means of disseminating this information. Much of the technical data is on user accessible data bases. The Center researches and writes a number of technical reports each year and publishes a newsletter monthly. Customized research is performed in response to specific inquiries from government and industry. MTIAC serves as a link between Government and Industry to strengthen the manufacturing technology base through the dissemination of advanced manufacturing information.

  4. Manufacturing Technology Information Analysis Center: Knowledge is strength

    NASA Astrophysics Data System (ADS)

    Safar, Michal

    1992-04-01

    The Center's primary function is to facilitate technology transfer within DoD, other government agencies and industry. The DoD has recognized the importance of technology transfer, not only to support specific weapon system manufacture, but to strengthen the industrial base that sustains DoD. MTIAC uses an experienced technical staff of engineers and information specialists to acquire, analyze, and disseminate technical information. Besides ManTech project data, MTIAC collects manufacturing technology from other government agencies, commercial publications, proceedings, and various international sources. MTIAC has various means of disseminating this information. Much of the technical data is on user accessible data bases. The Center researches and writes a number of technical reports each year and publishes a newsletter monthly. Customized research is performed in response to specific inquiries from government and industry. MTIAC serves as a link between Government and Industry to strengthen the manufacturing technology base through the dissemination of advanced manufacturing information.

  5. Intelligent Processing Equipment Developments Within the Navy's Manufacturing Technology Centers of Excellence

    NASA Technical Reports Server (NTRS)

    Nanzetta, Philip

    1992-01-01

    The U.S. Navy has had an active Manufacturing Technology (MANTECH) Program aimed at developing advanced production processes and equipment since the late-1960's. During the past decade, however, the resources of the MANTECH program were concentrated in Centers of Excellence. Today, the Navy sponsors four manufacturing technology Centers of Excellence: the Automated Manufacturing Research Facility (AMRF); the Electronics Manufacturing Productivity Facility (EMPF); the National Center for Excellence in Metalworking Technology (NCEMT); and the Center of Excellence for Composites Manufacturing Technology (CECMT). This paper briefly describes each of the centers and summarizes typical Intelligent Equipment Processing (IEP) projects that were undertaken.

  6. Emerging Global Trends in Advanced Manufacturing

    DTIC Science & Technology

    2012-03-01

    Analyses for ODNI,” for the Office of the Director of National Intelligence (ODNI). The views, opinions, and findings should not be construed as...changes in advanced manufacturing, the National Intelligence Manager for Science and Technology in the Office of the Director of National... Intelligence asked the Institute for Defense Analyses to identify emerging global trends in advanced manufacturing and to propose scenarios for advanced

  7. Isotope separation and advanced manufacturing technology

    NASA Astrophysics Data System (ADS)

    Carpenter, J.; Kan, T.

    This is the fourth issue of a semiannual report for the Isotope Separation and Advanced Materials Manufacturing (ISAM) Technology Program at Lawrence Livermore National Laboratory. Primary objectives include: (1) the Uranium Atomic Vapor Laser Isotope Separation (UAVLIS) process, which is being developed and prepared for deployment as an advanced uranium enrichment capability; (2) Advanced manufacturing technologies, which include industrial laser and E-beam material processing and new manufacturing technologies for uranium, plutonium, and other strategically important materials in support of DOE and other national applications. This report features progress in the ISAM Program from October 1993 through March 1994.

  8. 2001 Industry Studies: Advanced Manufacturing

    DTIC Science & Technology

    2007-11-02

    oriented, 19 and manufacturers are employing the Internet and associated information technologies to better integrate supply chains and form extended...producers, and suppliers. Focus will shift from within the enterprise to the entire market, with business- to-business ( B2B ) e-commerce becoming a...sufficiently disruptive (e.g. the Internet ), alter the course of industries and the broader economy. The transformation of manufacturing has involved

  9. Advanced manufacturing: Technology and international competitiveness

    SciTech Connect

    Tesar, A.

    1995-02-01

    Dramatic changes in the competitiveness of German and Japanese manufacturing have been most evident since 1988. All three countries are now facing similar challenges, and these challenges are clearly observed in human capital issues. Our comparison of human capital issues in German, Japanese, and US manufacturing leads us to the following key judgments: Manufacturing workforces are undergoing significant changes due to advanced manufacturing technologies. As companies are forced to develop and apply these technologies, the constituency of the manufacturing workforce (especially educational requirements, contingent labor, job content, and continuing knowledge development) is being dramatically and irreversibly altered. The new workforce requirements which result due to advanced manufacturing require a higher level of worker sophistication and responsibility.

  10. The Advanced Manufacturing Laboratory at RPI.

    ERIC Educational Resources Information Center

    Desrochers, A.; DeRusso, P. M.

    1984-01-01

    An Advanced Manufacturing Laboratory (AML) has been established at Rensselaer Polytechnic Institute (RPI). AML courses, course objectives, instructional strategies, student experiences in design and manufacturing, and AML equipment are discussed. Overall recommendations based on student and instructor experiences are also presented. (JN)

  11. Advanced Manufacturing Training: Mobile Learning Labs

    ERIC Educational Resources Information Center

    Vukich, John C.; Ackerman, Amanda A.

    2010-01-01

    Across Colorado, manufacturing employers forecast an on-going need not only for workers who are interested in career opportunities but who are prepared to enter the advanced manufacturing industry with the necessary high-tech skills. Additionally, employers report concerns about replacing retiring workers that take with them decades of…

  12. Center for Advanced Space Propulsion

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Center for Advanced Space Propulsion (CASP) is part of the University of Tennessee-Calspan Center for Aerospace Research (CAR). It was formed in 1985 to take advantage of the extensive research faculty and staff of the University of Tennessee and Calspan Corporation. It is also one of sixteen NASA sponsored Centers established to facilitate the Commercial Development of Space. Based on investigators' qualifications in propulsion system development, and matching industries' strong intent, the Center focused its efforts in the following technical areas: advanced chemical propulsion, electric propulsion, AI/Expert systems, fluids management in microgravity, and propulsion materials processing. This annual report focuses its discussion in these technical areas.

  13. A feasibility study for a manufacturing technology deployment center

    SciTech Connect

    Not Available

    1994-10-31

    The Automation & Robotics Research Institute (ARRI) and the Texas Engineering Extension Service (TEEX) were funded by the U.S. Department of Energy to determine the feasibility of a regional industrial technology institute to be located at the Superconducting Super Collider (SSC) Central Facility in Waxahachie, Texas. In response to this opportunity, ARRI and TEEX teamed with the DOE Kansas City Plant (managed by Allied Signal, Inc.), Los Alamos National Laboratory (managed by the University of California), Vought Aircraft Company, National Center for Manufacturing Sciences (NCMS), SSC Laboratory, KPMG Peat Marwick, Dallas County Community College, Navarro Community College, Texas Department of Commerce (TDOC), Texas Manufacturing Assistance Center (TMAC), Oklahoma Center for the Advancement of Science and Technology, Arkansas Science and Technology Authority, Louisiana Productivity Center, and the NASA Mid-Continent Technology Transfer Center (MCTTC) to develop a series of options, perform the feasibility analysis and secure industrial reviews of the selected concepts. The final report for this study is presented in three sections: Executive Summary, Business Plan, and Technical Plan. The results from the analysis of the proposed concept support the recommendation of creating a regional technology alliance formed by the states of Texas, New Mexico, Oklahoma, Arkansas and Louisiana through the conversion of the SSC Central facility into a Manufacturing Technology Deployment Center (MTDC).

  14. Advancing Manufacturing Research Through Competitions

    SciTech Connect

    Balakirsky, Stephen; Madhavan, Raj

    2009-01-01

    Competitions provide a technique for building interest and collaboration in targeted research areas. This paper will present a new competition that aims to increase collaboration amongst Universities, automation end-users, and automation manufacturers through a virtual competition. The virtual nature of the competition allows for reduced infrastructure requirements while maintaining realism in both the robotic equipment deployed and the scenarios. Details of the virtual environment as well as the competitions objectives, rules, and scoring metrics will be presented.

  15. Advanced Manufacturing of Superconducting Magnets

    NASA Technical Reports Server (NTRS)

    Senti, Mark W.

    1996-01-01

    The development of specialized materials, processes, and robotics technology allows for the rapid prototype and manufacture of superconducting and normal magnets which can be used for magnetic suspension applications. Presented are highlights of the Direct Conductor Placement System (DCPS) which enables automatic design and assembly of 3-dimensional coils and conductor patterns using LTS and HTS conductors. The system enables engineers to place conductors in complex patterns with greater efficiency and accuracy, and without the need for hard tooling. It may also allow researchers to create new types of coils and patterns which were never practical before the development of DCPS. The DCPS includes a custom designed eight-axis robot, patented end effector, CoilCAD(trademark) design software, RoboWire(trademark) control software, and automatic inspection.

  16. Nontoxic Resins Advance Aerospace Manufacturing

    NASA Technical Reports Server (NTRS)

    2009-01-01

    The 2008 NASA Commercial Invention of the Year, PETI-330, is a polyimide matrix resin that performs well at high temperatures and is easily processed into composites in a simple, short curing cycle. Invented by scientists at Langley Research Center, PETI-330 is now licensed to Ube Industries, based in Japan with its American headquarters in New York. In addition to being durable and lightweight, the resin is also nontoxic, which makes it safe for workers to handle. PETI-330 was created specifically for heat-resistant composites formed with resin transfer molding and resin infusion, which formerly could only be used with low temperature resin systems.

  17. Advances in recombinant antibody manufacturing.

    PubMed

    Kunert, Renate; Reinhart, David

    2016-04-01

    Since the first use of Chinese hamster ovary (CHO) cells for recombinant protein expression, production processes have steadily improved through numerous advances. In this review, we have highlighted several key milestones that have contributed to the success of CHO cells from the beginning of their use for monoclonal antibody (mAb) expression until today. The main factors influencing the yield of a production process are the time to accumulate a desired amount of biomass, the process duration, and the specific productivity. By comparing maximum cell densities and specific growth rates of various expression systems, we have emphasized the limiting parameters of different cellular systems and comprehensively described scientific approaches and techniques to improve host cell lines. Besides the quantitative evaluation of current systems, the quality-determining properties of a host cell line, namely post-translational modifications, were analyzed and compared to naturally occurring polyclonal immunoglobulin fractions from human plasma. In summary, numerous different expression systems for mAbs are available and also under scientific investigation. However, CHO cells are the most frequently investigated cell lines and remain the workhorse for mAb production until today.

  18. Development of Advanced Ceramic Manufacturing Technology

    SciTech Connect

    Pujari, V.K.

    2001-04-05

    Advanced structural ceramics are enabling materials for new transportation engine systems that have the potential for significantly reducing energy consumption and pollution in automobiles and heavy vehicles. Ceramic component reliability and performance have been demonstrated in previous U.S. DOE initiatives, but high manufacturing cost was recognized as a major barrier to commercialization. Norton Advanced Ceramics (NAC), a division of Saint-Gobain Industrial Ceramics, Inc. (SGIC), was selected to perform a major Advanced Ceramics Manufacturing Technology (ACMT) Program. The overall objectives of NAC's program were to design, develop, and demonstrate advanced manufacturing technology for the production of ceramic exhaust valves for diesel engines. The specific objectives were (1) to reduce the manufacturing cost by an order of magnitude, (2) to develop and demonstrate process capability and reproducibility, and (3) to validate ceramic valve performance, durability, and reliability. The program was divided into four major tasks: Component Design and Specification, Component Manufacturing Technology Development, Inspection and Testing, and Process Demonstration. A high-power diesel engine valve for the DDC Series 149 engine was chosen as the demonstration part for this program. This was determined to be an ideal component type to demonstrate cost-effective process enhancements, the beneficial impact of advanced ceramics on transportation systems, and near-term commercialization potential. The baseline valve material was NAC's NT451 SiAION. It was replaced, later in the program, by an alternate silicon nitride composition (NT551), which utilized a lower cost raw material and a simplified powder-processing approach. The material specifications were defined based on DDC's engine requirements, and the initial and final component design tasks were completed.

  19. Soft computing in design and manufacturing of advanced materials

    NASA Technical Reports Server (NTRS)

    Cios, Krzysztof J.; Baaklini, George Y; Vary, Alex

    1993-01-01

    The potential of fuzzy sets and neural networks, often referred to as soft computing, for aiding in all aspects of manufacturing of advanced materials like ceramics is addressed. In design and manufacturing of advanced materials, it is desirable to find which of the many processing variables contribute most to the desired properties of the material. There is also interest in real time quality control of parameters that govern material properties during processing stages. The concepts of fuzzy sets and neural networks are briefly introduced and it is shown how they can be used in the design and manufacturing processes. These two computational methods are alternatives to other methods such as the Taguchi method. The two methods are demonstrated by using data collected at NASA Lewis Research Center. Future research directions are also discussed.

  20. Advanced Engineering Environments: Implications for Aerospace Manufacturing

    NASA Technical Reports Server (NTRS)

    Thomas, D.

    2001-01-01

    There are significant challenges facing today's aerospace industry. Global competition, more complex products, geographically-distributed design teams, demands for lower cost, higher reliability and safer vehicles, and the need to incorporate the latest technologies quicker all face the developer of aerospace systems. New information technologies offer promising opportunities to develop advanced engineering environments (AEEs) to meet these challenges. Significant advances in the state-of-the-art of aerospace engineering practice are envisioned in the areas of engineering design and analytical tools, cost and risk tools, collaborative engineering, and high-fidelity simulations early in the development cycle. These advances will enable modeling and simulation of manufacturing methods, which will in turn allow manufacturing considerations to be included much earlier in the system development cycle. Significant cost savings, increased quality, and decreased manufacturing cycle time are expected to result. This paper will give an overview of the NASA's Intelligent Synthesis Environment, the agency initiative to develop an AEE, with a focus on the anticipated benefits in aerospace manufacturing.

  1. Recent manufacturing advances for spiral bevel gears

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.; Bill, Robert C.

    1991-01-01

    The U.S. Army Aviation Systems Command (AVSCOM), through the Propulsion Directorate at NASA LRC, has recently sponsored projects to advance the manufacturing process for spiral bevel gears. This type of gear is a critical component in rotary-wing propulsion systems. Two successfully completed contracted projects are described. The first project addresses the automated inspection of spiral bevel gears through the use of coordinate measuring machines. The second project entails the computer-numerical-control (CNC) conversion of a spiral bevel gear grinding machine that is used for all aerospace spiral bevel gears. The results of these projects are described with regard to the savings effected in manufacturing time.

  2. Center for Advanced Computational Technology

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.

    2000-01-01

    The Center for Advanced Computational Technology (ACT) was established to serve as a focal point for diverse research activities pertaining to application of advanced computational technology to future aerospace systems. These activities include the use of numerical simulations, artificial intelligence methods, multimedia and synthetic environments, and computational intelligence, in the modeling, analysis, sensitivity studies, optimization, design and operation of future aerospace systems. The Center is located at NASA Langley and is an integral part of the School of Engineering and Applied Science of the University of Virginia. The Center has four specific objectives: 1) conduct innovative research on applications of advanced computational technology to aerospace systems; 2) act as pathfinder by demonstrating to the research community what can be done (high-potential, high-risk research); 3) help in identifying future directions of research in support of the aeronautical and space missions of the twenty-first century; and 4) help in the rapid transfer of research results to industry and in broadening awareness among researchers and engineers of the state-of-the-art in applications of advanced computational technology to the analysis, design prototyping and operations of aerospace and other high-performance engineering systems. In addition to research, Center activities include helping in the planning and coordination of the activities of a multi-center team of NASA and JPL researchers who are developing an intelligent synthesis environment for future aerospace systems; organizing workshops and national symposia; as well as writing state-of-the-art monographs and NASA special publications on timely topics.

  3. Marshall Space Flight Center Digital Manufacturing

    NASA Technical Reports Server (NTRS)

    Arays, Edward; Phillips, Steven

    2008-01-01

    This presentation highlights the history of DELMIA at MSFC; provides an overview of the Constellation Program; examines the manufacturing of Ares 1 Upper Stage; explains the digital manufacturing implementation for Ares 1 Upper Stage; and, discusses manufacturing and development problems and challenges.

  4. Exploring Competencies for Manufacturing Education Partnership Centers

    ERIC Educational Resources Information Center

    Chapman, Diane D.; Guerdat, Kate G.

    2012-01-01

    The National Institute of Standards and Technology's Hollings Manufacturing Extension Partnership works with U.S. manufacturers to help them create and retain jobs, increase profits, and save time and money. Members of the Manufacturing Extension Partnership recognized the need to expand capacity and capabilities of their network to address the…

  5. Integration of Advanced Simulation and Visualization for Manufacturing Process Optimization

    NASA Astrophysics Data System (ADS)

    Zhou, Chenn; Wang, Jichao; Tang, Guangwu; Moreland, John; Fu, Dong; Wu, Bin

    2016-05-01

    The integration of simulation and visualization can provide a cost-effective tool for process optimization, design, scale-up and troubleshooting. The Center for Innovation through Visualization and Simulation (CIVS) at Purdue University Northwest has developed methodologies for such integration with applications in various manufacturing processes. The methodologies have proven to be useful for virtual design and virtual training to provide solutions addressing issues on energy, environment, productivity, safety, and quality in steel and other industries. In collaboration with its industrial partnerships, CIVS has provided solutions to companies, saving over US38 million. CIVS is currently working with the steel industry to establish an industry-led Steel Manufacturing Simulation and Visualization Consortium through the support of National Institute of Standards and Technology AMTech Planning Grant. The consortium focuses on supporting development and implementation of simulation and visualization technologies to advance steel manufacturing across the value chain.

  6. Phase 1 Development Testing of the Advanced Manufacturing Demonstrator Engine

    NASA Technical Reports Server (NTRS)

    Case, Nicholas L.; Eddleman, David E.; Calvert, Marty R.; Bullard, David B.; Martin, Michael A.; Wall, Thomas R.

    2016-01-01

    The Additive Manufacturing Development Breadboard Engine (BBE) is a pressure-fed liquid oxygen/pump-fed liquid hydrogen (LOX/LH2) expander cycle engine that was built and operated by NASA at Marshall Space Flight Center's East Test Area. The breadboard engine was conceived as a technology demonstrator for the additive manufacturing technologies for an advanced upper stage prototype engine. The components tested on the breadboard engine included an ablative chamber, injector, main fuel valve, turbine bypass valve, a main oxidizer valve, a mixer and the fuel turbopump. All parts minus the ablative chamber were additively manufactured. The BBE was successfully hot fire tested seven times. Data collected from the test series will be used for follow on demonstration tests with a liquid oxygen turbopump and a regeneratively cooled chamber and nozzle.

  7. Center for Advanced Separation Technology

    SciTech Connect

    Honaker, Rick

    2013-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, CAST is now a five-university consortium – Virginia Tech, West Virginia University, University of Kentucky, University of Utah and Montana Tech, - that is supported through U.S. DOE Cooperative Agreement No. DE-FE0000699, Center for Advanced Separation Technology. Much of the research to be conducted with Cooperative Agreement funds will be longer term, high-risk, basic research and will be carried out in two broad areas: Advanced Pre-Combustion Clean Coal Technologies and Gas-Gas Separations. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the five member universities. These were reviewed and the selected proposals were forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed below by category, along with abstracts from their final reports.

  8. Centers for manufacturing technology: Industrial Advisory Committee Review

    SciTech Connect

    1995-10-01

    An advisory committee, composed of senior managers form industrial- sector companies and major manufacturing trade associations and representatives from appropriate educational institutions, meets semi-annually to review and advise the Oak Ridge Centers for Manufacturing Technology (ORCMT) on its economic security program. Individual papers have been indexed separately for the database.

  9. Precision Casting via Advanced Simulation and Manufacturing

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A two-year program was conducted to develop and commercially implement selected casting manufacturing technologies to enable significant reductions in the costs of castings, increase the complexity and dimensional accuracy of castings, and reduce the development times for delivery of high quality castings. The industry-led R&D project was cost shared with NASA's Aerospace Industry Technology Program (AITP). The Rocketdyne Division of Boeing North American, Inc. served as the team lead with participation from Lockheed Martin, Ford Motor Company, Howmet Corporation, PCC Airfoils, General Electric, UES, Inc., University of Alabama, Auburn University, Robinson, Inc., Aracor, and NASA-LeRC. The technical effort was organized into four distinct tasks. The accomplishments reported herein. Task 1.0 developed advanced simulation technology for core molding. Ford headed up this task. On this program, a specialized core machine was designed and built. Task 2.0 focused on intelligent process control for precision core molding. Howmet led this effort. The primary focus of these experimental efforts was to characterize the process parameters that have a strong impact on dimensional control issues of injection molded cores during their fabrication. Task 3.0 developed and applied rapid prototyping to produce near net shape castings. Rocketdyne was responsible for this task. CAD files were generated using reverse engineering, rapid prototype patterns were fabricated using SLS and SLA, and castings produced and evaluated. Task 4.0 was aimed at developing technology transfer. Rocketdyne coordinated this task. Casting related technology, explored and evaluated in the first three tasks of this program, was implemented into manufacturing processes.

  10. Space Technology Mission Directorate Game Changing Development Program FY2015 Annual Program Review: Advanced Manufacturing Technology

    NASA Technical Reports Server (NTRS)

    Vickers, John; Fikes, John

    2015-01-01

    The Advance Manufacturing Technology (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of the Initiative is the Advanced Manufacturing National Program Office (AMNPO), which includes participation from all federal agencies involved in U.S. manufacturing. In support of the AMNPO the AMT Project supports building and Growing the National Network for Manufacturing Innovation through a public-private partnership designed to help the industrial community accelerate manufacturing innovation. Integration with other projects/programs and partnerships: STMD (Space Technology Mission Directorate), HEOMD, other Centers; Industry, Academia; OGA's (e.g., DOD, DOE, DOC, USDA, NASA, NSF); Office of Science and Technology Policy, NIST Advanced Manufacturing Program Office; Generate insight within NASA and cross-agency for technology development priorities and investments. Technology Infusion Plan: PC; Potential customer infusion (TDM, HEOMD, SMD, OGA, Industry); Leverage; Collaborate with other Agencies, Industry and Academia; NASA roadmap. Initiatives include: Advanced Near Net Shape Technology Integrally Stiffened Cylinder Process Development (launch vehicles, sounding rockets); Materials Genome; Low Cost Upper Stage-Class Propulsion; Additive Construction with Mobile Emplacement (ACME); National Center for Advanced Manufacturing.

  11. The Role of Advanced Manufacturing in Our Journey to Mars

    NASA Technical Reports Server (NTRS)

    Keys, Andrew S.

    2017-01-01

    The National Additive Manufacturing Innovation Institute was launched in August 2012 as a result of President Obama's proposed need for a whole-of-government advanced manufacturing effort. Mission: To accelerate the adoption of additive manufacturing technologies to increase domestic manufacturing competitiveness. Funding: Five federal agencies - the Departments of Defense, Energy, and Commerce, the National Science Foundation, and NASA - jointly committed to invest $45 million.

  12. Organizational Considerations for Advanced Manufacturing Technology

    ERIC Educational Resources Information Center

    DeRuntz, Bruce D.; Turner, Roger M.

    2003-01-01

    In the last several decades, the United States has experienced a decline in productivity, while the world has seen a maturation of the global marketplace. Nations have moved manufacturing strategy and process technology issues to the top of management priority lists. The issues surrounding manufacturing technologies and their implementations have…

  13. Center for advanced microstructures and devices (CAMD)

    NASA Astrophysics Data System (ADS)

    Craft, B. C.; Feldman, M.; Morikawa, E.; Poliakoff, E. D.; Saile, V.; Scott, J. D.; Stockbauer, R. L.

    1992-01-01

    The new synchrotron-radiation facility, Center for Advanced Microstructures and Devices, at Louisiana State University is described with regard to the status of installation of the storage ring, implementation of the various programs, and construction of the first beamlines.

  14. Advances in gamma titanium aluminides and their manufacturing techniques

    NASA Astrophysics Data System (ADS)

    Kothari, Kunal; Radhakrishnan, Ramachandran; Wereley, Norman M.

    2012-11-01

    Gamma titanium aluminides display attractive properties for high temperature applications. For over a decade in the 1990s, the attractive properties of titanium aluminides were outweighed by difficulties encountered in processing and machining at room temperature. But advances in manufacturing technologies, deeper understanding of titanium aluminides microstructure, deformation mechanisms, and advances in micro-alloying, has led to the production of gamma titanium aluminide sheets. An in-depth review of key advances in gamma titanium aluminides is presented, including microstructure, deformation mechanisms, and alloy development. Traditional manufacturing techniques such as ingot metallurgy and investment casting are reviewed and advances via powder metallurgy based manufacturing techniques are discussed. Finally, manufacturing challenges facing gamma titanium aluminides, as well as avenues to overcome them, are discussed.

  15. Evaluation of advanced polymers for additive manufacturing

    SciTech Connect

    Rios, Orlando; Morrison, Crystal

    2015-09-01

    The goal of this Manufacturing Demonstration Facility (MDF) technical collaboration project between Oak Ridge National Laboratory (ORNL) and PPG Industries, Inc. was to evaluate the feasibility of using conventional coatings chemistry and technology to build up material layer-by-layer. The PPG-ORNL study successfully demonstrated that polymeric coatings formulations may overcome many limitations of common thermoplastics used in additive manufacturing (AM), allow lightweight nozzle design for material deposition and increase build rate. The materials effort focused on layer-by-layer deposition of coatings with each layer fusing together. The combination of materials and deposition results in an additively manufactured build that has sufficient mechanical properties to bear the load of additional layers, yet is capable of bonding across the z-layers to improve build direction strength. The formulation properties were tuned to enable a novel, high-throughput deposition method that is highly scalable, compatible with high loading of reinforcing fillers, and is inherently low-cost.

  16. Advanced Blade Manufacturing Project - Final Report

    SciTech Connect

    POORE, ROBERT Z.

    1999-08-01

    The original scope of the project was to research improvements to the processes and materials used in the manufacture of wood-epoxy blades, conduct tests to qualify any new material or processes for use in blade design and subsequently build and test six blades using the improved processes and materials. In particular, ABM was interested in reducing blade cost and improving quality. In addition, ABM needed to find a replacement material for the mature Douglas fir used in the manufacturing process. The use of mature Douglas fir is commercially unacceptable because of its limited supply and environmental concerns associated with the use of mature timber. Unfortunately, the bankruptcy of FloWind in June 1997 and a dramatic reduction in AWT sales made it impossible for ABM to complete the full scope of work. However, sufficient research and testing were completed to identify several promising changes in the blade manufacturing process and develop a preliminary design incorporating these changes.

  17. Advanced manufacturing technologies on color plasma displays

    NASA Astrophysics Data System (ADS)

    Betsui, Keiichi

    2000-06-01

    The mass production of the color plasma display started from 1996. However, since the price of the panel is still expensive, PDPs are not in widespread use at home. It is necessary to develop the new and low-cost manufacturing technologies to reduce the price of the panel. This paper describes some of the features of new fabrication technologies of PDPs.

  18. Energy intensity, electricity consumption, and advanced manufacturing-technology usage

    SciTech Connect

    Doms, M.E.; Dunne, T.

    1995-07-01

    This article reports on the relationship between the usage of advanced manufacturing technologies (AMTs) and energy consumption patterns in manufacturing plants. Using data from the Survey of Manufacturing Technology and the 1987 Census of Manufactures, we model the energy intensity and the electricity intensity of plants as functions of AMT usage and plant age. The main findings are that plants that utilize AMTs are less-energy intensive than plants not using AMTs, but consume proportionately more electricity as a fuel source. Additionally, older plants are generally more energy intensive and rely on fossil fuels to a greater extent than younger plants. 25 refs., 3 tabs.

  19. Advanced Manufacturing as an Online Case Study for Global Geography Education

    ERIC Educational Resources Information Center

    Glass, Michael R.; Kalafsky, Ronald V.; Drake, Dawn M.

    2013-01-01

    Advanced manufacturing continues to be an important sector for emerging and industrialized economies, therefore, remaining an important topic for economic geography education. This article describes a case study created for the Association of American Geographer's Center for Global Geography Education and its implementation. The international…

  20. Advanced materials manufacturing for solar energy

    NASA Astrophysics Data System (ADS)

    van Mierlo, Frank

    2012-02-01

    The US has a robust technical roadmap to get to a 1/W total installed cost with several potential winners in the race. We dominate in the new technology arena and there is a good chance that tomorrow's winning technology will be from the current crop of contenders. One potential breakthrough is Direct Wafer^TM a new manufacturing technique to make silicon wafers at a fraction of the traditional cost. Current wafer manufacturing is a multi-step, energy- and capital-intensive process that wastes half of the valuable silicon feedstock. 1366's Direct Wafer technology forms a standard, 156mm multi-crystalline wafer directly from molten silicon in a semi-continuous, efficient, high-throughput process that eliminates silicon waste. Direct Wafer^TM cuts the amount of consumables by a factor of four and requires only half the capital per GigaWatt production capacity thus enabling solar to compete successfully with coal generated electricity.

  1. Pollution prevention assessment for a manufacturer of electrical load centers

    SciTech Connect

    Jendrucko, R.J.; Thomas, T.M.; Looby, G.P.

    1995-09-01

    The US Environmental Protection Agency (EPA) has funded a pilot project to assist small and medium-size manufacturers who want to minimize their generation of waste but who lack the expertise to do so. In an effort to assist these manufacturers Waste Minimization Assessment Centers (WMACs) were established at selected universities and procedures were adapted from the EPA Waste Minimization Opportunity Assessment Manual. The WMAC team at the University of Tennessee performed an assessment at a plant that manufacturers electrical load centers. Raw materials, including coiled sheet steel and coiled copper strips, polystyrene pellets, and miscellaneous fasteners, are used in metal-working, injection molding, painting, and assembly operations. The team`s report, detailed findings and recommendations, indicated that a large quantity of waste overflow rinse water is generated and that significant cost savings could be achieved by installing valves that will allow operators to turn off the flow during periods of nonuse. This Research Brief was developed by the principal investigators and EPA`s National Risk Management Research Laboratory, Cincinnati, OH, to announce key findings of an ongoing research project that is fully documented in a separate report of the same title available from University City Science Center.

  2. Co-Extrusion: Advanced Manufacturing for Energy Devices

    SciTech Connect

    Cobb, Corie Lynn

    2016-11-18

    The development of mass markets for large-format batteries, including electric vehicles (EVs) and grid support, depends on both cost reductions and performance enhancements to improve their economic viability. Palo Alto Research Center (PARC) has developed a multi-material, advanced manufacturing process called co-extrusion (CoEx) to remove multiple steps in a conventional battery coating process with the potential to simultaneously increase battery energy and power density. CoEx can revolutionize battery manufacturing across most chemistries, significantly lowering end-product cost and shifting the underlying economics to make EVs and other battery applications a reality. PARC’s scale-up of CoEx for electric vehicle (EV) batteries builds on a solid base of experience in applying CoEx to solar cell manufacturing, deposition of viscous ceramic pastes, and Li-ion battery chemistries. In the solar application, CoEx has been deployed commercially at production scale where multi-channel CoEx printheads are used to print viscous silver gridline pastes at full production speeds (>40 ft/min). This operational scale-up provided invaluable experience with the nuances of speed, yield, and maintenance inherent in taking a new technology to the factory floor. PARC has leveraged this experience, adapting the CoEx process for Lithium-ion (Li-ion) battery manufacturing. To date, PARC has worked with Li-ion battery materials and structured cathodes with high-density Li-ion regions and low-density conduction regions, documenting both energy and power performance. Modeling results for a CoEx cathode show a path towards a 10-20% improvement in capacity for an EV pouch cell. Experimentally, we have realized a co-extruded battery structure with a Lithium Nickel Manganese Cobalt (NMC) cathode at print speeds equivalent to conventional roll coating processes. The heterogeneous CoEx cathode enables improved capacity in thick electrodes at higher C-rates. The proof-of-principle coin cells

  3. Materials/manufacturing element of the Advanced Turbine Systems Program

    SciTech Connect

    Karnitz, M.A.; Holcomb, R.S.; Wright, I.G.

    1995-10-01

    The technology based portion of the Advanced Turbine Systems Program (ATS) contains several subelements which address generic technology issues for land-based gas-turbine systems. One subelement is the Materials/Manufacturing Technology Program which is coordinated by DOE-Oak Ridge Operations and Oak Ridge National Laboratory (ORNL). The work in this subelement is being performed predominantly by industry with assistance from universities and the national laboratories. Projects in this subelement are aimed toward hastening the incorporation of new materials and components in gas turbines. A materials/manufacturing plan was developed in FY 1994 with input from gas turbine manufacturers, materials suppliers, universities, and government laboratories. The plan outlines seven major subelements which focus on materials issues and manufacturing processes. Work is currently under way in four of the seven major subelements. There are now major projects on coatings and process development, scale-up of single crystal airfoil manufacturing technology, materials characterization, and technology information exchange.

  4. Copper Disk Manufactured at the Space Optics Manufacturing and Technology Center

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This photograph shows Wes Brown, Marshall Space Flight Center's (MSFC's) lead diamond tuner, an expert in the science of using diamond-tipped tools to cut metal, inspecting the mold's physical characteristics to ensure the uniformity of its more than 6,000 grooves. This king-size copper disk, manufactured at the Space Optics Manufacturing and Technology Center (SOMTC) at MSFC, is a special mold for making high resolution monitor screens. This master mold will be used to make several other molds, each capable of forming hundreds of screens that have a type of lens called a fresnel lens. Weighing much less than conventional optics, fresnel lenses have multiple concentric grooves, each formed to a precise angle, that together create the curvature needed to focus and project images. The MSFC leads NASA's space optics manufacturing technology development as a technology leader for diamond turning. The machine used to manufacture this mold is among many one-of-a-kind pieces of equipment of MSFC's SOMTC.

  5. Center for Advanced Modeling and Simulation Intern

    SciTech Connect

    Gertman, Vanessa

    2010-01-01

    Some interns just copy papers and seal envelopes. Not at INL! Check out how Vanessa Gertman, an INL intern working at the Center for Advanced Modeling and Simulation, spent her summer working with some intense visualization software. Lots more content like this is available at INL's facebook page http://www.facebook.com/idahonationallaboratory.

  6. Advanced Biomedical Computing Center (ABCC) | DSITP

    Cancer.gov

    The Advanced Biomedical Computing Center (ABCC), located in Frederick Maryland (MD), provides HPC resources for both NIH/NCI intramural scientists and the extramural biomedical research community. Its mission is to provide HPC support, to provide collaborative research, and to conduct in-house research in various areas of computational biology and biomedical research.

  7. Center for Advanced Modeling and Simulation Intern

    ScienceCinema

    Gertman, Vanessa

    2016-07-12

    Some interns just copy papers and seal envelopes. Not at INL! Check out how Vanessa Gertman, an INL intern working at the Center for Advanced Modeling and Simulation, spent her summer working with some intense visualization software. Lots more content like this is available at INL's facebook page http://www.facebook.com/idahonationallaboratory.

  8. Advanced technologies for Mission Control Centers

    NASA Technical Reports Server (NTRS)

    Dalton, John T.; Hughes, Peter M.

    1991-01-01

    Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

  9. Industrial Assessment Centers - Small Manufacturers Reduce Energy & Increase Productivity

    SciTech Connect

    2015-11-06

    Since 1976, the Industrial Assessment Centers (IACs), administered by the US Department of Energy, have supported small and medium-sized American manufacturers to reduce energy use and increase their productivity and competitiveness. The 24 IACs, located at premier engineering universities around the country (see below), send faculty and engineering students to local small and medium-sized manufacturers to provide no-cost assessments of energy use, process performance and waste and water flows. Under the direction of experienced professors, IAC engineering students analyze the manufacturer’s facilities, energy bills and energy, waste and water systems, including compressed air, motors/pumps, lighting, process heat and steam. The IACs then follow up with written energy-saving and productivity improvement recommendations, with estimates of related costs and payback periods.

  10. The Ceramic Manufacturability Center: A new partnership with US industry

    SciTech Connect

    Tennery, V.J.; Morris, T.O.

    1993-12-01

    The Ceramic Manufacturability Center (CMC) is a new facility at the Oak Ridge National Laboratory (ORNL) established as a direct response to current US industry needs. It was created as part of a highly integrated program jointly funded by the US Department of Energy Defense Programs, Energy Efficiency and Renewable Energy, and Energy Research divisions. The CMC is staffed by personnel from ORNL and the Y-12 Plant, both managed by Martin Marietta Energy Systems, Inc. (Energy Systems). Its mission is to improve the technology needed to manufacture high-precision ceramic components inexpensively and reliably. This mission can be accomplished by strengthening the US machine tool industry and by joining with ceramic material suppliers and end users to provide a path to commercialization of these ceramic components.

  11. Prosperity Game: Advanced Manufacturing Day, May 17, 1994

    SciTech Connect

    Berman, M.

    1994-12-01

    Prosperity Games are an outgrowth and adaptation of move/countermove and seminar War Games. Prosperity Games are simulations that explore complex issues in a variety of areas including economics, politics, sociology, environment, education and research. These issues can be examined from a variety of perspectives ranging from a global, macroeconomic and geopolitical viewpoint down to the details of customer/supplier/market interactions in specific industries. All Prosperity Games are unique in that both the game format and the player contributions vary from game to game. This report documents a 90-minute Prosperity Game conducted as part of Advanced Manufacturing Day on May 17, 1994. This was the fourth game conducted under the direction of the Center for National Industrial Alliances at Sandia. Although previous games lasted from one to two days, this abbreviated game produced interesting and important results. Most of the strategies proposed in previous games were reiterated here. These included policy changes in international trade, tax laws, the legal system, and the educational system. Government support of new technologies was encouraged as well as government-industry partnerships. The importance of language in international trade was an original contribution of this game. The deliberations and recommendations of these teams provide valuable insights as to the views of this diverse group of decision makers concerning policy changes, foreign competition, and the development, delivery and commercialization of new technologies.

  12. Space manufacturing systems and the Space Operations Center

    NASA Technical Reports Server (NTRS)

    Louviere, A. J.

    1982-01-01

    For the planned Space Operations Center (SOC) and envisioned space manufacturing and processes systems, the concepts of phased programs, development and operations, station-keeping orbit envelopes, propulsive harbor tugs, and aspects of servicing are discussed. The SOC three-phased program concept includes the servicing of satellites in compatible orbits and in transition to higher energy orbits. Two concepts of a free-flyer satellite are assessed, including the fuel system, and the placement of such a satellite into orbit is discussed. Finally, some services that will be provided by SOC are mentioned.

  13. Regional Advanced Manufacturing Academy: An Agent of Change

    ERIC Educational Resources Information Center

    Schmeling, Daniel M.; Rose, Kevin

    2010-01-01

    Three Northeast Texas community colleges put aside service delivery areas and matters of "turf" to create Centers of Excellence that provided training throughout a nine county area. This consortium; along with 14 manufacturers, seven economic development corporations, and the regional workforce board, led the change in training a highly…

  14. The Effect of the Implementation of Advanced Manufacturing Technologies on Training in the Manufacturing Sector

    ERIC Educational Resources Information Center

    Castrillon, Isabel Dieguez; Cantorna, Ana I. Sinde

    2005-01-01

    Purpose: The aim of this article is to gain insight into some of the factors that determine personnel-training efforts in companies introducing advanced manufacturing technologies (AMTs). The study provides empirical evidence from a sector with high rates of technological modernisation. Design/methodology/approach: "Ad hoc" survey of 90…

  15. Process development status report for advanced manufacturing projects

    SciTech Connect

    Brinkman, J.R.; Homan, D.A.

    1990-03-30

    This is the final status report for the approved Advanced Manufacturing Projects for FY 1989. Five of the projects were begun in FY 1987, one in FY 1988, and one in FY 1989. The approved projects cover technology areas in welding, explosive material processing and evaluation, ion implantation, and automated manufacturing. It is expected that the successful completion of these projects well result in improved quality and/or reduced cost for components produced by Mound. Those projects not brought to completion will be continued under Process development in FY 1990.

  16. Manufacturing technologies

    NASA Astrophysics Data System (ADS)

    The Manufacturing Technologies Center is at the core of Sandia National Laboratories' advanced manufacturing effort which spans the entire product realization process. The center's capabilities in product and process development are summarized in the following disciplines: (1) mechanical - rapid prototyping, manufacturing engineering, machining and computer-aided manufacturing, measurement and calibration, and mechanical and electronic manufacturing liaison; (2) electronics - advanced packaging for microelectronics, printed circuits, and electronic fabrication; and (3) materials - ceramics, glass, thin films, vacuum technology, brazing, polymers, adhesives, composite materials, and process analysis.

  17. Advanced composite aileron for L-1011 transport aircraft: Aileron manufacture

    NASA Technical Reports Server (NTRS)

    Dunning, E. G.; Cobbs, W. L.; Legg, R. L.

    1981-01-01

    The fabrication activities of the Advanced Composite Aileron (ACA) program are discussed. These activities included detail fabrication, manufacturing development, assembly, repair and quality assurance. Five ship sets of ailerons were manufactured. The detail fabrication effort of ribs, spar and covers was accomplished on male tools to a common cure cycle. Graphite epoxy tape and fabric and syntactic epoxy materials were utilized in the fabrication. The ribs and spar were net cured and required no post cure trim. Material inconsistencies resulted in manufacturing development of the front spar during the production effort. The assembly effort was accomplished in subassembly and assembly fixtures. The manual drilling system utilized a dagger type drill in a hydraulic feed control hand drill. Coupon testing for each detail was done.

  18. Spacesuit glove manufacturing enhancements through the use of advanced technologies

    NASA Technical Reports Server (NTRS)

    Cadogan, David; Bradley, David; Kosmo, Joseph

    1993-01-01

    The sucess of astronauts performing extravehicular activity (EVA) on orbit is highly dependent upon the performance of their spacesuit gloves.A study has recently been conducted to advance the development and manufacture of spacesuit gloves. The process replaces the manual techniques of spacesuit glove manufacture by utilizing emerging technologies such as laser scanning, Computer Aided Design (CAD), computer generated two-dimensional patterns from three-dimensionl surfaces, rapid prototyping technology, and laser cutting of materials, to manufacture the new gloves. Results of the program indicate that the baseline process will not increase the cost of the gloves as compared to the existing styles, and in production, may reduce the cost of the gloves. perhaps the most important outcome of the Laserscan process is that greater accuracy and design control can be realized. Greater accuracy was achieved in the baseline anthropometric measurement and CAD data measurement which subsequently improved the design feature. This effectively enhances glove performance through better fit and comfort.

  19. Spacesuit glove manufacturing enhancements through the use of advanced technologies

    NASA Astrophysics Data System (ADS)

    Cadogan, David; Bradley, David; Kosmo, Joseph

    The sucess of astronauts performing extravehicular activity (EVA) on orbit is highly dependent upon the performance of their spacesuit gloves.A study has recently been conducted to advance the development and manufacture of spacesuit gloves. The process replaces the manual techniques of spacesuit glove manufacture by utilizing emerging technologies such as laser scanning, Computer Aided Design (CAD), computer generated two-dimensional patterns from three-dimensionl surfaces, rapid prototyping technology, and laser cutting of materials, to manufacture the new gloves. Results of the program indicate that the baseline process will not increase the cost of the gloves as compared to the existing styles, and in production, may reduce the cost of the gloves. perhaps the most important outcome of the Laserscan process is that greater accuracy and design control can be realized. Greater accuracy was achieved in the baseline anthropometric measurement and CAD data measurement which subsequently improved the design feature. This effectively enhances glove performance through better fit and comfort.

  20. Center for Advanced Energy Studies Program Plan

    SciTech Connect

    Kevin Kostelnik

    2005-09-01

    The world is facing critical energy-related challenges regarding world and national energy demands, advanced science and energy technology delivery, nuclear engineering educational shortfalls, and adequately trained technical staff. Resolution of these issues is important for the United States to ensure a secure and affordable energy supply, which is essential for maintaining U.S. national security, continued economic prosperity, and future sustainable development. One way that the U.S. Department of Energy (DOE) is addressing these challenges is by tasking the Battelle Energy Alliance, LLC (BEA) with developing the Center for Advanced Energy Studies (CAES) at the Idaho National Laboratory (INL). By 2015, CAES will be a self-sustaining, world-class, academic and research institution where the INL; DOE; Idaho, regional, and other national universities; and the international community will cooperate to conduct critical energy-related research, classroom instruction, technical training, policy conceptualization, public dialogue, and other events.

  1. Advanced Manufacturing Systems in Food Processing and Packaging Industry

    NASA Astrophysics Data System (ADS)

    Shafie Sani, Mohd; Aziz, Faieza Abdul

    2013-06-01

    In this paper, several advanced manufacturing systems in food processing and packaging industry are reviewed, including: biodegradable smart packaging and Nano composites, advanced automation control system consists of fieldbus technology, distributed control system and food safety inspection features. The main purpose of current technology in food processing and packaging industry is discussed due to major concern on efficiency of the plant process, productivity, quality, as well as safety. These application were chosen because they are robust, flexible, reconfigurable, preserve the quality of the food, and efficient.

  2. Advanced Manufacturing for a U.S. Clean Energy Economy (Fact Sheet)

    SciTech Connect

    Not Available

    2012-03-01

    This fact sheet is an overview of the U.S. Department of Energy's Advanced Manufacturing Office. Manufacturing is central to our economy, culture, and history. The industrial sector produces 11% of U.S. gross domestic product (GDP), employs 12 million people, and generates 57% of U.S. export value. However, U.S. industry consumes about one-third of all energy produced in the United States, and significant cost-effective energy efficiency and advanced manufacturing opportunities remain unexploited. As a critical component of the National Innovation Policy for Advanced Manufacturing, the U.S. Department of Energy's (DOE's) Advanced Manufacturing Office (AMO) is focused on creating a fertile environment for advanced manufacturing innovation, enabling vigorous domestic development of transformative manufacturing technologies, promoting coordinated public and private investment in precompetitive advanced manufacturing technology infrastructure, and facilitating the rapid scale-up and market penetration of advanced manufacturing technologies.

  3. 78 FR 34346 - Proposed Information Collection; Comment Request; NIST MEP Advanced Manufacturing Jobs and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ... Advanced Manufacturing Jobs and Innovation Accelerator Challenge (AMJIAC) Client Impact Survey AGENCY... information collection. The purpose of the Advanced Manufacturing Jobs and Innovation Accelerator Challenge... to support job creation, encourage economic development, and enhance the competitiveness of...

  4. Manufacturing technologies

    SciTech Connect

    1995-09-01

    The Manufacturing Technologies Center is an integral part of Sandia National Laboratories, a multiprogram engineering and science laboratory, operated for the Department of Energy (DOE) with major facilities at Albuquerque, New Mexico, and Livermore, California. Our Center is at the core of Sandia`s Advanced Manufacturing effort which spans the entire product realization process.

  5. Center for Advanced Gas Turbine Systems Research

    SciTech Connect

    Golan, L.P.

    1992-12-31

    An unregulated conventional power station based on the Rankine Cycle typically bums pulverized coal in a boiler that exports steam for expansion through a steam turbine which ultimately drives an electric generator. The flue gases are normally cleaned of particulates by an electrostatic precipitator or bag house. A basic cycle such as this will have an efficiency of approximately 35% with 10% of the energy released through the stack and 55% to cooling water. Advanced gas turbine based combustion systems have the potential to be environmentally and commercially superior to existing conventional technology. however, to date, industry, academic, and government groups have not coordinated their effort to commercialize these technologies. The Center for Advanced Gas Turbine Systems Research will provide the medium to support effective commercialization of this technology. Several cycles or concepts for advanced gas turbine systems that could be fired on natural gas or could be adapted into coal based systems have been proposed (for examples, see Figures 4, 5, 6, and 7) (2) all with vary degrees of complexity, research needs, and system potential. Natural gas fired power systems are now available with 52% efficiency ratings; however, with a focused base technology program, it is expected that the efficiency levels can be increased to the 60% level and beyond. This increase in efficiency will significantly reduce the environmental burden and reduce the cost of power generation.

  6. Center for Advanced Gas Turbine Systems Research

    SciTech Connect

    Golan, L.P.

    1992-01-01

    An unregulated conventional power station based on the Rankine Cycle typically bums pulverized coal in a boiler that exports steam for expansion through a steam turbine which ultimately drives an electric generator. The flue gases are normally cleaned of particulates by an electrostatic precipitator or bag house. A basic cycle such as this will have an efficiency of approximately 35% with 10% of the energy released through the stack and 55% to cooling water. Advanced gas turbine based combustion systems have the potential to be environmentally and commercially superior to existing conventional technology. however, to date, industry, academic, and government groups have not coordinated their effort to commercialize these technologies. The Center for Advanced Gas Turbine Systems Research will provide the medium to support effective commercialization of this technology. Several cycles or concepts for advanced gas turbine systems that could be fired on natural gas or could be adapted into coal based systems have been proposed (for examples, see Figures 4, 5, 6, and 7) (2) all with vary degrees of complexity, research needs, and system potential. Natural gas fired power systems are now available with 52% efficiency ratings; however, with a focused base technology program, it is expected that the efficiency levels can be increased to the 60% level and beyond. This increase in efficiency will significantly reduce the environmental burden and reduce the cost of power generation.

  7. 10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology...

  8. 10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology...

  9. A manufacturing database of advanced materials used in spacecraft structures

    NASA Technical Reports Server (NTRS)

    Bao, Han P.

    1994-01-01

    Cost savings opportunities over the life cycle of a product are highest in the early exploratory phase when different design alternatives are evaluated not only for their performance characteristics but also their methods of fabrication which really control the ultimate manufacturing costs of the product. In the past, Design-To-Cost methodologies for spacecraft design concentrated on the sizing and weight issues more than anything else at the early so-called 'Vehicle Level' (Ref: DOD/NASA Advanced Composites Design Guide). Given the impact of manufacturing cost, the objective of this study is to identify the principal cost drivers for each materials technology and propose a quantitative approach to incorporating these cost drivers into the family of optimization tools used by the Vehicle Analysis Branch of NASA LaRC to assess various conceptual vehicle designs. The advanced materials being considered include aluminum-lithium alloys, thermoplastic graphite-polyether etherketone composites, graphite-bismaleimide composites, graphite- polyimide composites, and carbon-carbon composites. Two conventional materials are added to the study to serve as baseline materials against which the other materials are compared. These two conventional materials are aircraft aluminum alloys series 2000 and series 7000, and graphite-epoxy composites T-300/934. The following information is available in the database. For each material type, the mechanical, physical, thermal, and environmental properties are first listed. Next the principal manufacturing processes are described. Whenever possible, guidelines for optimum processing conditions for specific applications are provided. Finally, six categories of cost drivers are discussed. They include, design features affecting processing, tooling, materials, fabrication, joining/assembly, and quality assurance issues. It should be emphasized that this database is not an exhaustive database. Its primary use is to make the vehicle designer

  10. Feature-based tolerancing for advanced manufacturing applications

    SciTech Connect

    Brown, C.W.; Kirk, W.J. III; Simons, W.R.; Ward, R.C.; Brooks, S.L.

    1994-11-01

    A primary requirement for the successful deployment of advanced manufacturing applications is the need for a complete and accessible definition of the product. This product definition must not only provide an unambiguous description of a product`s nominal shape but must also contain complete tolerance specification and general property attributes. Likewise, the product definition`s geometry, topology, tolerance data, and modeler manipulative routines must be fully accessible through a robust application programmer interface. This paper describes a tolerancing capability using features that complements a geometric solid model with a representation of conventional and geometric tolerances and non-shape property attributes. This capability guarantees a complete and unambiguous definition of tolerances for manufacturing applications. An object-oriented analysis and design of the feature-based tolerance domain was performed. The design represents and relates tolerance features, tolerances, and datum reference frames. The design also incorporates operations that verify correctness and check for the completeness of the overall tolerance definition. The checking algorithm is based upon the notion of satisfying all of a feature`s toleranceable aspects. Benefits from the feature-based tolerance modeler include: advancing complete product definition initiatives, incorporating tolerances in product data exchange, and supplying computer-integrated manufacturing applications with tolerance information.

  11. Advances in the manufacturing, types, and applications of biosensors

    NASA Astrophysics Data System (ADS)

    Ravindra, Nuggehalli M.; Prodan, Camelia; Fnu, Shanmugamurthy; Padronl, Ivan; Sikha, Sushil K.

    2007-12-01

    In recent years, there have been significant technological advancements in the manufacturing, types, and applications of biosensors. Applications include clinical and non-clinical diagnostics for home, bio-defense, bio-remediation, environment, agriculture, and the food industry. Biosensors have progressed beyond the detection of biological threats such as anthrax and are finding use in a number of non-biological applications. Emerging biosensor technologies such as lab-on-a-chip have revolutionized the integration approaches for a very flexible, innovative, and user-friendly platform. An overview of the fundamentals, types, applications, and manufacturers, as well as the market trends of biosensors is presented here. Two case studies are discussed: one focused on a characterization technique—patch clamping and dielectric spectroscopy as a biological sensor—and the other about lithium phthalocyanine, a material that is being developed for in-vivo oxymetry.

  12. CENTER FOR ADVANCED SEPARATION TECHNOLOGY (CAST) PROGRAM

    SciTech Connect

    Yoon, Roe-Hoan; Hull, Christopher

    2014-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations.

  13. The New Center for Advanced Energy Studies

    SciTech Connect

    L.J. Bond; K. Kostelnik; R.A. Wharton; A. Kadak

    2006-06-01

    A secure and affordable energy supply is essential for achieving U.S. national security, in continuing U.S. prosperity and in laying the foundation to enable future economic growth. The next generation energy workforce in the U.S. is a critical element in meeting both national and global energy needs. The Center for Advanced Energy Studies (CAES) was established in 2005 in response to U.S. Department of Energy (DOE) requirements. CAES, located at the new Idaho National Laboratory (INL), will address critical energy education, research, policy study and training needs. CAES is a unique joint partnership between the Battelle Energy Alliance (BEA), the State of Idaho, an Idaho University Consortium (IUC), and a National University Consortium (NUC). CAES will be based in a new facility that will foster collaborative academic and research efforts among participating institutions.

  14. Center for Advanced Space Propulsion (CASP)

    NASA Technical Reports Server (NTRS)

    1988-01-01

    With a mission to initiate and conduct advanced propulsion research in partnership with industry, and a goal to strengthen U.S. national capability in propulsion technology, the Center for Advanced Space Propulsion (CASP) is the only NASA Center for Commercial Development of Space (CCDS) which focuses on propulsion and associated technologies. Meetings with industrial partners and NASA Headquarters personnel provided an assessment of the constraints placed on, and opportunities afforded commercialization projects. Proprietary information, data rights, and patent rights were some of the areas where well defined information is crucial to project success and follow-on efforts. There were five initial CASP projects. At the end of the first year there are six active, two of which are approaching the ground test phase in their development. Progress in the current six projects has met all milestones and is detailed. Working closely with the industrial counterparts it was found that the endeavors in expert systems development, computational fluid dynamics, fluid management in microgravity, and electric propulsion were well received. One project with the Saturn Corporation which dealt with expert systems application in the assembly process, was placed on hold pending further direction from Saturn. The Contamination Measurment and Analysis project was not implemented since CASP was unable to identify an industrial participant. Additional propulsion and related projects were investigated during the year. A subcontract was let to a small business, MicroCraft, Inc., to study rocket engine certification standards. The study produced valuable results; however, based on a number of factors it was decided not to pursue this project further.

  15. The Advanced Technology Development Center (ATDC)

    NASA Technical Reports Server (NTRS)

    Clements, G. R.; Willcoxon, R. (Technical Monitor)

    2001-01-01

    NASA is building the Advanced Technology Development Center (ATDC) to provide a 'national resource' for the research, development, demonstration, testing, and qualification of Spaceport and Range Technologies. The ATDC will be located at Space Launch Complex 20 (SLC-20) at Cape Canaveral Air Force Station (CCAFS) in Florida. SLC-20 currently provides a processing and launch capability for small-scale rockets; this capability will be augmented with additional ATDC facilities to provide a comprehensive and integrated in situ environment. Examples of Spaceport Technologies that will be supported by ATDC infrastructure include densified cryogenic systems, intelligent automated umbilicals, integrated vehicle health management systems, next-generation safety systems, and advanced range systems. The ATDC can be thought of as a prototype spaceport where industry, government, and academia, in partnership, can work together to improve safety of future space initiatives. The ATDC is being deployed in five separate phases. Major ATDC facilities will include a Liquid Oxygen Area; a Liquid Hydrogen Area, a Liquid Nitrogen Area, and a multipurpose Launch Mount; 'Iron Rocket' Test Demonstrator; a Processing Facility with a Checkout and Control System; and Future Infrastructure Developments. Initial ATDC development will be completed in 2006.

  16. Advanced manufacturing technologies for the BeCOAT telescope

    NASA Astrophysics Data System (ADS)

    Sweeney, Michael N.; Rajic, Slobodan; Seals, Roland D.

    1994-02-01

    The beryllium cryogenic off-axis telescope (BeCOAT) uses a two-mirror, non re-imaging, off- axis, Ritchey Chretian design with all-beryllium optics, structures and baffles. The purpose of this telescope is the system level demonstration of advanced manufacturing technologies for optics, optical benches, and baffle assemblies. The key issues that are addressed are single point diamond turning of beryllium optics, survivable fastening techniques, minimum beryllium utilization, and technologies leading to self-aligning, all-beryllium optical systems.

  17. Advanced computational research in materials processing for design and manufacturing

    SciTech Connect

    Zacharia, T.

    1994-12-31

    The computational requirements for design and manufacture of automotive components have seen dramatic increases for producing automobiles with three times the mileage. Automotive component design systems are becoming increasingly reliant on structural analysis requiring both overall larger analysis and more complex analyses, more three-dimensional analyses, larger model sizes, and routine consideration of transient and non-linear effects. Such analyses must be performed rapidly to minimize delays in the design and development process, which drives the need for parallel computing. This paper briefly describes advanced computational research in superplastic forming and automotive crash worthiness.

  18. Chrysler Partners with North Lake High School in an Advanced Manufacturing Technology Program for Special Needs Students.

    ERIC Educational Resources Information Center

    Karbon, Patrick J.; Kuhn, Cynthia

    1996-01-01

    Chrysler Corporation and North Lake High School cooperated to develop and deploy Advanced Manufacturing Technology for high school students identified as at risk or hard to serve. Chrysler provided curriculum that was delivered by training center instructors; teachers ensured student competence in academic areas. (JOW)

  19. Advanced Manufacturing Processes Laboratory Building 878 hazards assessment document

    SciTech Connect

    Wood, C.; Thornton, W.; Swihart, A.; Gilman, T.

    1994-07-01

    The introduction of the hazards assessment process is to document the impact of the release of hazards at the Advanced Manufacturing Processes Laboratory (AMPL) that are significant enough to warrant consideration in Sandia National Laboratories` operational emergency management program. This hazards assessment is prepared in accordance with the Department of Energy Order 5500.3A requirement that facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment provides an analysis of the potential airborne release of chemicals associated with the operations and processes at the AMPL. This research and development laboratory develops advanced manufacturing technologies, practices, and unique equipment and provides the fabrication of prototype hardware to meet the needs of Sandia National Laboratories, Albuquerque, New Mexico (SNL/NM). The focus of the hazards assessment is the airborne release of materials because this requires the most rapid, coordinated emergency response on the part of the AMPL, SNL/NM, collocated facilities, and surrounding jurisdiction to protect workers, the public, and the environment.

  20. Clean Energy Manufacturing Analysis Center. 2015 Research Highlights -- Carbon Fiber

    SciTech Connect

    Das, Sujit

    2016-03-01

    CEMAC has conducted four major studies on the manufacturing of clean energy technologies. Three of these focused on the end product: solar photovoltaic modules, wind turbines, and automotive lithium-ion batteries. The fourth area focused on a key material for manufacturing clean energy technologies, carbon fiber.

  1. 10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle Manufacturing Facility Award Program, 10 CFR part 611, subpart C, awards for eligible projects....

  2. 10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle Manufacturing Facility Award Program, 10 CFR part 611, subpart C, awards for eligible projects....

  3. 10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle Manufacturing Facility Award Program, 10 CFR part 611, subpart C, awards for eligible projects....

  4. Influence of Manufacturing Processes and Microstructures on the Performance and Manufacturability of Advanced High Strength Steels

    SciTech Connect

    Choi, Kyoo Sil; Liu, Wenning N.; Sun, Xin; Khaleel, Mohammad A.

    2009-10-01

    Advanced high strength steels (AHSS) are performance-based steel grades and their global material properties can be achieved with various steel chemistries and manufacturing processes, leading to various microstructures. In this paper, we investigate the influence of supplier variation and resulting microstructure difference on the overall mechanical properties as well as local formability behaviors of advanced high strength steels (AHSS). For this purpose, we first examined the basic material properties and the transformation kinetics of TRansformation Induced Plasticity (TRIP) 800 steels from three different suppliers under different testing temperatures. The experimental results show that there is a significant supplier (i.e., manufacturing process) dependency of the TRIP 800 steel mechanical and microstructure properties. Next, we examined the local formability of two commercial Dual Phase (DP) 980 steels during stamping process. The two commercial DP 980 steels also exhibit noticeably different formability during stamping process in the sense that one of them shows severe tendency for shear fracture. Microstructure-based finite element analyses are carried out next to simulate the localized deformation process with the two DP 980 microstructures, and the results suggest that the possible reason for the difference in formability lies in the morphology of the hard martensite phase in the DP microstructure.

  5. Clean Energy Manufacturing Analysis Center (CEMAC) 2015 Research Highlights

    SciTech Connect

    Woodhouse, Michael; Mone, Christopher; Chung, Donald; Elgqvist, Emma; Das, Sujit; Mann, Margaret; Gossett, Scott

    2016-03-01

    CEMAC has conducted four major studies on the manufacturing of clean energy technologies. Three of these focused on the end product: solar photovoltaic modules, wind turbines, and automotive lithium-ion batteries. The fourth area focused on a key material for manufacturing clean energy technologies, carbon fiber. This booklet summarizes key findings of CEMAC work to date, describes CEMAC's research methodology, and describes work to come.

  6. National Center for Advancing Translational Sciences

    MedlinePlus

    ... Groups Work with NCATS Research Team Advances Evatar Female Reproductive System Through its Tissue Chip for Drug Screening program, ... parasites and bacteria. More... Research Team Advances Evatar Female Reproductive System Through its Tissue Chip for Drug Screening program, ...

  7. Advanced manufacturing by spray forming: Aluminum strip and microelectromechanical systems

    SciTech Connect

    McHugh, K.M.

    1994-12-31

    Spray forming is an advanced materials processing technology that converts a bulk liquid metal to a near-net-shape solid by depositing atomized droplets onto a suitably shaped substrate. By combining rapid solidification processing with product shape control, spray forming can reduce manufacturing costs while improving product quality. INEL is developing a unique spray-forming method based on de Laval (converging/diverging) nozzle designs to produce near-net-shape solids and coatings of metals, polymers, and composite materials. Properties of the spray-formed material are tailored by controlling the characteristics of the spray plume and substrate. Two examples are described: high-volume production of aluminum alloy strip, and the replication of micron-scale features in micropatterned polymers during the production of microelectromechanical systems.

  8. Developing novel 3D antennas using advanced additive manufacturing technology

    NASA Astrophysics Data System (ADS)

    Mirzaee, Milad

    In today's world of wireless communication systems, antenna engineering is rapidly advancing as the wireless services continue to expand in support of emerging commercial applications. Antennas play a key role in the performance of advanced transceiver systems where they serve to convert electric power to electromagnetic waves and vice versa. Researchers have held significant interest in developing this crucial component for wireless communication systems by employing a variety of design techniques. In the past few years, demands for electrically small antennas continues to increase, particularly among portable and mobile wireless devices, medical electronics and aerospace systems. This trend toward smaller electronic devices makes the three dimensional (3D) antennas very appealing, since they can be designed in a way to use every available space inside the devise. Additive Manufacturing (AM) method could help to find great solutions for the antennas design for next generation of wireless communication systems. In this thesis, the design and fabrication of 3D printed antennas using AM technology is studied. To demonstrate this application of AM, different types of antennas structures have been designed and fabricated using various manufacturing processes. This thesis studies, for the first time, embedded conductive 3D printed antennas using PolyLactic Acid (PLA) and Acrylonitrile Butadiene Styrene (ABS) for substrate parts and high temperature carbon paste for conductive parts which can be a good candidate to overcome the limitations of direct printing on 3D surfaces that is the most popular method to fabricate conductive parts of the antennas. This thesis also studies, for the first time, the fabrication of antennas with 3D printed conductive parts which can contribute to the new generation of 3D printed antennas.

  9. Center for the Advancement of Health

    MedlinePlus

    ... YouTube CFAH PARTNERS Alliance for Quality Psychosocial Cancer Care Kellogg Health Scholars Program KP Burch Leadership Program Diversity Data Place, Migration & Health Network * The Center for ...

  10. Prediction-based manufacturing center self-adaptive demand side energy optimization in cyber physical systems

    NASA Astrophysics Data System (ADS)

    Sun, Xinyao; Wang, Xue; Wu, Jiangwei; Liu, Youda

    2014-05-01

    Cyber physical systems(CPS) recently emerge as a new technology which can provide promising approaches to demand side management(DSM), an important capability in industrial power systems. Meanwhile, the manufacturing center is a typical industrial power subsystem with dozens of high energy consumption devices which have complex physical dynamics. DSM, integrated with CPS, is an effective methodology for solving energy optimization problems in manufacturing center. This paper presents a prediction-based manufacturing center self-adaptive energy optimization method for demand side management in cyber physical systems. To gain prior knowledge of DSM operating results, a sparse Bayesian learning based componential forecasting method is introduced to predict 24-hour electric load levels for specific industrial areas in China. From this data, a pricing strategy is designed based on short-term load forecasting results. To minimize total energy costs while guaranteeing manufacturing center service quality, an adaptive demand side energy optimization algorithm is presented. The proposed scheme is tested in a machining center energy optimization experiment. An AMI sensing system is then used to measure the demand side energy consumption of the manufacturing center. Based on the data collected from the sensing system, the load prediction-based energy optimization scheme is implemented. By employing both the PSO and the CPSO method, the problem of DSM in the manufacturing center is solved. The results of the experiment show the self-adaptive CPSO energy optimization method enhances optimization by 5% compared with the traditional PSO optimization method.

  11. Center for Space Power and Advanced Electronics, Auburn University

    NASA Technical Reports Server (NTRS)

    Deis, Dan W.; Hopkins, Richard H.

    1991-01-01

    The union of Auburn University's Center for Space Power and Advanced Electronics and the Westinghouse Science and Technology Center to form a Center for the Commercial Development of Space (CCDS) is discussed. An area of focus for the CCDS will be the development of silicon carbide electronics technology, in terms of semiconductors and crystal growth. The discussion is presented in viewgraph form.

  12. Industrial Assessment Center Helps Boost Efficiency for Small and Medium Manufacturers

    SciTech Connect

    Johnson, Mark; Friedman, David

    2016-12-15

    The Industrial Assessment Center program helps small and medium manufacturers boost efficiency and save energy. It pairs companies with universities as students perform energy assessments and provide recommendations to improve their facilities.

  13. Industrial Assessment Center Helps Boost Efficiency for Small and Medium Manufacturers

    ScienceCinema

    Johnson, Mark; Friedman, David

    2017-01-06

    The Industrial Assessment Center program helps small and medium manufacturers boost efficiency and save energy. It pairs companies with universities as students perform energy assessments and provide recommendations to improve their facilities.

  14. Impacts of advanced manufacturing technology on parametric estimating

    NASA Astrophysics Data System (ADS)

    Hough, Paul G.

    1989-12-01

    The introduction of advanced manufacturing technology in the aerospace industry poses serious challenges for government cost analysts. Traditionally, the analysts have relied on parametric estimating techniques for both planning and budgeting. Despite its problems, this approach has proven to be a remarkably useful and robust tool for estimating new weapon system costs. However, rapid improvements in both product and process technology could exacerbate current difficulties, and diminish the utility of the parametric approach. This paper reviews some weakness associated with parametrics, then proceeds to examine how specific aspects of the factory of the future may further impact parametric estimating, and suggests avenues of research for their resolution. This paper is an extended version of Cost Estimating for the Factory of the Future. Parametric estimating is a method by which aggregated costs are derived as a function of high-level product characteristics or parameters. The resulting equations are known as cost estimating relationships (CERs). Such equations are particularly useful when detailed technical specifications are not available.

  15. Advanced Manufacturing Technologies (AMT): Additive Manufactured Hot Fire Planning and Testing in GRC Cell 32 Project

    NASA Technical Reports Server (NTRS)

    Fikes, John C.

    2014-01-01

    The objective of this project is to hot fire test an additively manufactured thrust chamber assembly TCA (injector and thrust chamber). GRC will install the additively manufactured Inconel 625 injector, two additively manufactured (SLM) water cooled Cu-Cr thrust chamber barrels and one additively manufactured (SLM) water cooled Cu-Cr thrust chamber nozzle on the test stand in Cell 32 and perform hot fire testing of the integrated TCA.

  16. Center for Advanced Space Propulsion Second Annual Technical Symposium Proceedings

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The proceedings for the Center for Advanced Space Propulsion Second Annual Technical Symposium are divided as follows: Chemical Propulsion, CFD; Space Propulsion; Electric Propulsion; Artificial Intelligence; Low-G Fluid Management; and Rocket Engine Materials.

  17. Cosmos, an international center for advanced studies

    NASA Technical Reports Server (NTRS)

    Ryzhov, Iurii; Alifanov, Oleg; Sadin, Stanley; Coleman, Paul

    1990-01-01

    The concept of Cosmos, a Soviet operating center for aerospace activities, is presented. The main Cosmos participants are the Institute for Aerospace Education, the Institute for Research and Commercial Development, and the Department of Space Policy and Socio-Economic Studies. Cosmos sponsors a number of educational programs, basic research, and studies of the social impact of space-related technologies.

  18. Center For Advanced Energy Studies Overview

    ScienceCinema

    Blackman, Harold

    2016-07-12

    A collaboration between Idaho National Laboratory, Boise State University, Idaho State University and the University of Idaho. Conducts research in nuclear energy, advanced materials, carbon management, bioenergy, energy policy, modeling and simulation, and energy efficiency. Educates next generation of energy workforce. Visit us at www.caesenergy.org.

  19. Center For Advanced Energy Studies Overview

    SciTech Connect

    Blackman, Harold

    2011-01-01

    A collaboration between Idaho National Laboratory, Boise State University, Idaho State University and the University of Idaho. Conducts research in nuclear energy, advanced materials, carbon management, bioenergy, energy policy, modeling and simulation, and energy efficiency. Educates next generation of energy workforce. Visit us at www.caesenergy.org.

  20. Ergonomic Challenges in Conventional and Advanced Apparel Manufacturing.

    DTIC Science & Technology

    1992-10-01

    control systems. In Skill Based Automated Manufacturing : Proceedings of the IFAC Workshop by P. Brodner (ed.) (Pergamon Press, New York), pp. 47 - 52... In Skill Based Automated Manufacturing : Proceedings of the IFAC Workshop, ed. P. Brodner, 7-12. New York:Pergamon Press. Torner, M., G. Blide, H... New York:Pergamon Press. Weissbach, H. J. 1986. Design and Implementation Strategies of Manufacturing Control Systems. In Skill Based Automated

  1. Lightweighting Automotive Materials for Increased Fuel Efficiency and Delivering Advanced Modeling and Simulation Capabilities to U.S. Manufacturers

    SciTech Connect

    Hale, Steve

    2013-09-11

    Abstract The National Center for Manufacturing Sciences (NCMS) worked with the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL), to bring together research and development (R&D) collaborations to develop and accelerate the knowledgebase and infrastructure for lightweighting materials and manufacturing processes for their use in structural and applications in the automotive sector. The purpose/importance of this DOE program: • 2016 CAFÉ standards. • Automotive industry technology that shall adopt the insertion of lightweighting material concepts towards manufacturing of production vehicles. • Development and manufacture of advanced research tools for modeling and simulation (M&S) applications to reduce manufacturing and material costs. • U.S. competitiveness that will help drive the development and manufacture of the next generation of materials. NCMS established a focused portfolio of applied R&D projects utilizing lightweighting materials for manufacture into automotive structures and components. Areas that were targeted in this program: • Functionality of new lightweighting materials to meet present safety requirements. • Manufacturability using new lightweighting materials. • Cost reduction for the development and use of new lightweighting materials. The automotive industry’s future continuously evolves through innovation, and lightweight materials are key in achieving a new era of lighter, more efficient vehicles. Lightweight materials are among the technical advances needed to achieve fuel/energy efficiency and reduce carbon dioxide (CO2) emissions: • Establish design criteria methodology to identify the best materials for lightweighting. • Employ state-of-the-art design tools for optimum material development for their specific applications. • Match new manufacturing technology to production volume. • Address new process variability with new production-ready processes.

  2. Advanced Manufacturing Methods for Systems of Microsystem Nanospacecraft- Status of the Project

    NASA Astrophysics Data System (ADS)

    Plesseria, J. Y.; Corbelli, A.; Masse, C.; Rigo, O.; Pambaguian, L.; Bonvoisin, B.

    2014-06-01

    In the frame of an ESA TRP project, CSL, SIRRIS, ALMASpace and TAS-F associated to evaluate advanced manufacturing methods for application to space hardware.The state of the art of the new manufacturing methods, including additive manufacturing but also advanced bonding, joining and shaping techniques has been reviewed. Then three types of case studies have been developed successively. The first type was a re- manufacture of an existing piece of hardware using advanced techniques to evaluate if there is some potential improvement to be achieved (cost, production time, complexity reduction). The second level was to design and manufacture a part based on the application requirements. The last level was to design and manufacture a part taking into account the subsystem to which it belongs. All case studies have been tested in terms of achieved performances and resistance to the mechanical and thermal environment.

  3. Training Welders in Advanced Manufacturing Philosophies Nets Employability

    ERIC Educational Resources Information Center

    Wilson, Kristin

    2011-01-01

    As of September 2010, the U.S. manufacturing sector grew for the 14th consecutive month, leading some economists to speculate that, as with the Great Depression, American manufacturing will lead the economy out of the recession. It is a little bit of good news in a long stream of depressing employment reports. Career and technical educators…

  4. Multiscale and Multiphysics Modeling of Additive Manufacturing of Advanced Materials

    NASA Technical Reports Server (NTRS)

    Liou, Frank; Newkirk, Joseph; Fan, Zhiqiang; Sparks, Todd; Chen, Xueyang; Fletcher, Kenneth; Zhang, Jingwei; Zhang, Yunlu; Kumar, Kannan Suresh; Karnati, Sreekar

    2015-01-01

    The objective of this proposed project is to research and develop a prediction tool for advanced additive manufacturing (AAM) processes for advanced materials and develop experimental methods to provide fundamental properties and establish validation data. Aircraft structures and engines demand materials that are stronger, useable at much higher temperatures, provide less acoustic transmission, and enable more aeroelastic tailoring than those currently used. Significant improvements in properties can only be achieved by processing the materials under nonequilibrium conditions, such as AAM processes. AAM processes encompass a class of processes that use a focused heat source to create a melt pool on a substrate. Examples include Electron Beam Freeform Fabrication and Direct Metal Deposition. These types of additive processes enable fabrication of parts directly from CAD drawings. To achieve the desired material properties and geometries of the final structure, assessing the impact of process parameters and predicting optimized conditions with numerical modeling as an effective prediction tool is necessary. The targets for the processing are multiple and at different spatial scales, and the physical phenomena associated occur in multiphysics and multiscale. In this project, the research work has been developed to model AAM processes in a multiscale and multiphysics approach. A macroscale model was developed to investigate the residual stresses and distortion in AAM processes. A sequentially coupled, thermomechanical, finite element model was developed and validated experimentally. The results showed the temperature distribution, residual stress, and deformation within the formed deposits and substrates. A mesoscale model was developed to include heat transfer, phase change with mushy zone, incompressible free surface flow, solute redistribution, and surface tension. Because of excessive computing time needed, a parallel computing approach was also tested. In addition

  5. A new synchrotron light source at Louisiana State University's Center for Advanced Microstructures and Devices

    NASA Astrophysics Data System (ADS)

    Stockbauer, Roger L.; Ajmera, Pratul; Poliakoff, Erwin D.; Craft, Ben C.; Saile, Volker

    1990-05-01

    A 1.2-GeV synchrotron light source is being constructed at the Center for Advanced Microstructures and Devices (CAMD) at Louisiana State University. The expressed purpose of the center, which has been funded by a grant from the US Department of Energy, is to develop X-ray lithography techniques for manufacturing microcircuits, although basic science programs are also being established. The storage ring will be optimized for the soft-X-ray region and will be the first commercially manufactured electron storage ring in the United States. The magnetic lattice is based on a design developed by Chasman and Green and will allow up to three insertion devices to be installed for higher-energy and higher-intensity radiation. In addition to the lithography effort, experimental programs are being established in physics, chemistry, and related areas.

  6. Advanced modeling and simulation to design and manufacture high performance and reliable advanced microelectronics and microsystems.

    SciTech Connect

    Nettleship, Ian (University of Pittsburgh, Pittsburgh, PA); Hinklin, Thomas; Holcomb, David Joseph; Tandon, Rajan; Arguello, Jose Guadalupe, Jr.; Dempsey, James Franklin; Ewsuk, Kevin Gregory; Neilsen, Michael K.; Lanagan, Michael (Pennsylvania State University, University Park, PA)

    2007-07-01

    An interdisciplinary team of scientists and engineers having broad expertise in materials processing and properties, materials characterization, and computational mechanics was assembled to develop science-based modeling/simulation technology to design and reproducibly manufacture high performance and reliable, complex microelectronics and microsystems. The team's efforts focused on defining and developing a science-based infrastructure to enable predictive compaction, sintering, stress, and thermomechanical modeling in ''real systems'', including: (1) developing techniques to and determining materials properties and constitutive behavior required for modeling; (2) developing new, improved/updated models and modeling capabilities, (3) ensuring that models are representative of the physical phenomena being simulated; and (4) assessing existing modeling capabilities to identify advances necessary to facilitate the practical application of Sandia's predictive modeling technology.

  7. Transfer of advanced manufacturing technologies to eastern Kentucky industries

    SciTech Connect

    Gillies, J.A.; Kruzich, R.

    1988-05-01

    This study concludes that there are opportunities to provide assistance in the adoption of manufacturing technologies for small- and medium-sized firms in eastern Kentucky. However, the new markets created by Toyota are not adequate to justify a directed technology transfer program targeting the auto supply industry in eastern Kentucky because supplier markets have been determined for some time, and manufacturers in eastern Kentucky were not competitive in this early selection process. The results of the study strongly reinforce a reorientation of state business-assistance programs. The study also concludes that the quality and quantity of available labor is a pervasive problem in eastern Kentucky and has particular relevance as the economy changes. The study also investigated what type of technology-transfer programs would be appropriate to assist manufacturing firms in eastern Kentucky and if there were a critical number of firms to make such a program feasible.

  8. Cost analysis of advanced turbine blade manufacturing processes

    NASA Technical Reports Server (NTRS)

    Barth, C. F.; Blake, D. E.; Stelson, T. S.

    1977-01-01

    A rigorous analysis was conducted to estimate relative manufacturing costs for high technology gas turbine blades prepared by three candidate materials process systems. The manufacturing costs for the same turbine blade configuration of directionally solidified eutectic alloy, an oxide dispersion strengthened superalloy, and a fiber reinforced superalloy were compared on a relative basis to the costs of the same blade currently in production utilizing the directional solidification process. An analytical process cost model was developed to quantitatively perform the cost comparisons. The impact of individual process yield factors on costs was also assessed as well as effects of process parameters, raw materials, labor rates and consumable items.

  9. In-Space Manufacturing at NASA Marshall Space Flight Center: Enabling Technologies for Exploration

    NASA Technical Reports Server (NTRS)

    Bean, Quincy; Johnston, Mallory; Ordonez, Erick; Ryan, Rick; Prater, Tracie; Werkeiser, Niki

    2015-01-01

    NASA Marshall Space Flight Center is currently engaged in a number of in-space manufacturing(ISM)activities that have the potential to reduce launch costs, enhance crew safety, and provide the capabilities needed to undertake long duration spaceflight safely and sustainably.

  10. 78 FR 36595 - Manufacturer of Controlled Substances, Notice of Registration, National Center for Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Registration, National Center for Natural Products Research-NIDA; Correction In Federal Register (FR DOC) 2013-09325 on page 23597, in...

  11. 77 FR 12563 - Manufacturing Extension Partnership (MEP) Centers for South Dakota and Kentucky; Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... provide manufacturing extension services that enhance productivity, innovative capacity, and technological... compared to existing Centers will be a factor in evaluation of proposals. 2. Technology Resources. Does the... evaluation process. Review and Selection Process: The review and selection process and selection...

  12. Innovation Training within the Australian Advanced Manufacturing Industry

    ERIC Educational Resources Information Center

    Donovan, Jerome Denis; Maritz, Alex; McLellan, Andrew

    2013-01-01

    Innovation has emerged as a core driver for the future profitability and success of the manufacturing sector, and increasingly both governments and the private sector are examining ways to support the development of innovation capabilities within organisations. In this research, we have evaluated a government-funded innovation training course…

  13. Advanced excimer laser technologies enable green semiconductor manufacturing

    NASA Astrophysics Data System (ADS)

    Fukuda, Hitomi; Yoo, Youngsun; Minegishi, Yuji; Hisanaga, Naoto; Enami, Tatsuo

    2014-03-01

    "Green" has fast become an important and pervasive topic throughout many industries worldwide. Many companies, especially in the manufacturing industries, have taken steps to integrate green initiatives into their high-level corporate strategies. Governments have also been active in implementing various initiatives designed to increase corporate responsibility and accountability towards environmental issues. In the semiconductor manufacturing industry, there are growing concerns over future environmental impact as enormous fabs expand and new generation of equipments become larger and more powerful. To address these concerns, Gigaphoton has implemented various green initiatives for many years under the EcoPhoton™ program. The objective of this program is to drive innovations in technology and services that enable manufacturers to significantly reduce both the financial and environmental "green cost" of laser operations in high-volume manufacturing environment (HVM) - primarily focusing on electricity, gas and heat management costs. One example of such innovation is Gigaphoton's Injection-Lock system, which reduces electricity and gas utilization costs of the laser by up to 50%. Furthermore, to support the industry's transition from 300mm to the next generation 450mm wafers, technologies are being developed to create lasers that offer double the output power from 60W to 120W, but reducing electricity and gas consumption by another 50%. This means that the efficiency of lasers can be improve by up to 4 times in 450mm wafer production environments. Other future innovations include the introduction of totally Heliumfree Excimer lasers that utilize Nitrogen gas as its replacement for optical module purging. This paper discusses these and other innovations by Gigaphoton to enable green manufacturing.

  14. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2006-05-15

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  15. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-11-04

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  16. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher E. Hull

    2006-09-30

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  17. Center for Advanced Technology Training (CATT) Feasibility Study.

    ERIC Educational Resources Information Center

    Albuquerque Technical Vocational Inst., NM.

    A study of the feasibility of establishing a Center for Advanced Technology Training (CATT) at the Albuquerque Technical Vocational Institute (TVI Community College, New Mexico) was conducted by members of the Albuquerque business community, government representatives, and college administrators. Phase 1 of the study was an examination of the…

  18. The Advanced Technology Environmental Education Center Summer Fellows Institute.

    ERIC Educational Resources Information Center

    Depken, Diane E.; Zeman, Catherine L.; Lensch, Ellen Kabat; Brown, Edward J.

    2002-01-01

    Describes the background, activities, and outcomes of the Advanced Technology Environmental Education Center (ATEEC) and its Summer Fellows Institutes as a model for disciplinary and cross-disciplinary infusion of environmental science and technology content, curriculum, and methods into the classroom. Presents experiences, themes, and activities…

  19. Advanced manufacturing of SIMOX for low power electronics

    NASA Astrophysics Data System (ADS)

    Alles, Michael; Krull, Wade

    1996-04-01

    Silicon-on-insulator (SOI) has emerged as a key technology for low power electronics. The merits of SOI technology have been demonstrated, and are gaining acceptance in the semiconductor industry. In order for the SOI approach to be viable, several factors must converge, including the availability of SOI substrates in sufficient quantity, of acceptable quality, and at a competitive price. This work describes developments in SIMOX manufacturing technology and summarizes progress in each of these areas.

  20. Analysis of the influence of advanced materials for aerospace products R&D and manufacturing cost

    NASA Astrophysics Data System (ADS)

    Shen, A. W.; Guo, J. L.; Wang, Z. J.

    2015-12-01

    In this paper, we pointed out the deficiency of traditional cost estimation model about aerospace products Research & Development (R&D) and manufacturing based on analyzing the widely use of advanced materials in aviation products. Then we put up with the estimating formulas of cost factor, which representing the influences of advanced materials on the labor cost rate and manufacturing materials cost rate. The values ranges of the common advanced materials such as composite materials, titanium alloy are present in the labor and materials two aspects. Finally, we estimate the R&D and manufacturing cost of F/A-18, F/A- 22, B-1B and B-2 aircraft based on the common DAPCA IV model and the modified model proposed by this paper. The calculation results show that the calculation precision improved greatly by the proposed method which considering advanced materials. So we can know the proposed method is scientific and reasonable.

  1. Mask manufacturing of advanced technology designs using multi-beam lithography (part 2)

    NASA Astrophysics Data System (ADS)

    Green, Michael; Ham, Young; Dillon, Brian; Kasprowicz, Bryan; Hur, Ik Boum; Park, Joong Hee; Choi, Yohan; McMurran, Jeff; Kamberian, Henry; Chalom, Daniel; Klikovits, Jan; Jurkovic, Michal; Hudek, Peter

    2016-09-01

    As optical lithography is extended into 10nm and below nodes, advanced designs are becoming a key challenge for mask manufacturers. Techniques including advanced optical proximity correction (OPC) and Inverse Lithography Technology (ILT) result in structures that pose a range of issues across the mask manufacturing process. Among the new challenges are continued shrinking sub-resolution assist features (SRAFs), curvilinear SRAFs, and other complex mask geometries that are counter-intuitive relative to the desired wafer pattern. Considerable capability improvements over current mask making methods are necessary to meet the new requirements particularly regarding minimum feature resolution and pattern fidelity. Advanced processes using the IMS Multi-beam Mask Writer (MBMW) are feasible solutions to these coming challenges. In this paper, Part 2 of our study, we further characterize an MBMW process for 10nm and below logic node mask manufacturing including advanced pattern analysis and write time demonstration.

  2. Part A - Advanced turbine systems. Part B - Materials/manufacturing element of the Advanced Turbine Systems Program

    SciTech Connect

    Karnitz, M.A.

    1996-06-01

    The DOE Offices of Fossil Energy and Energy Efficiency and Renewable Energy have initiated a program to develop advanced turbine systems for power generation. The objective of the Advanced Turbine Systems (ATS) Program is to develop ultra-high efficiency, environmentally superior, and cost competitive gas turbine systems for utility and industrial applications. One of the supporting elements of the ATS Program is the Materials/Manufacturing Technologies Task. The objective of this element is to address the critical materials and manufacturing issues for both industrial and utility gas turbines.

  3. The rehabilitation engineering research center for the advancement of cognitive technologies.

    PubMed

    Heyn, Patricia Cristine; Cassidy, Joy Lucille; Bodine, Cathy

    2015-02-01

    Barring few exceptions, allied health professionals, engineers, manufacturers of assistive technologies (ATs), and consumer product manufacturers have developed few technologies for individuals with cognitive impairments (CIs). In 2004, the National Institute on Disability Rehabilitation Research (NIDRR) recognized the need to support research in this emergent field. They funded the first Rehabilitation Engineering Research Center for the Advancement of Cognitive Technologies (RERC-ACT). The RERC-ACT has since designed and evaluated existing and emerging technologies through rigorous research, improving upon existing AT devices, and creating new technologies for individuals with CIs. The RERC-ACT has contributed to the development and testing of AT products that assist persons with CIs to actively engage in tasks of daily living at home, school, work, and in the community. This article highlights the RERC-ACT's engineering development and research projects and discusses how current research may impact the quality of life for an aging population.

  4. Materials/manufacturing support element for the Advanced Turbine Systems Program

    SciTech Connect

    Karnitz, M.A.; Hoffman, E.E.; Parks, W.P.

    1994-12-31

    In 1993, DOE initiated a program to develop advanced gas turbines for power generation in utility and industrial applications. A materials/manufacturing plan was developed in several stages with input from gas turbine manufacturers, materials suppliers, universities, and government laboratories. This plan was developed by a small advanced materials and turbine technology team over a 6-month period. The technology plan calls for initiation of several high priority projects in FY 1995. The technical program for the materials/manufacturing element focuses on generic materials issues, components, and manufacturing processes. Categories include coatings and process development, turbine airfoil development, ceramics adaptation, directional solidification and single crystal airfoils manufactoring technology, materials characterization, catalytic combustor materials, and technology information exchange.

  5. Emerging technology: A key enabler for modernizing pharmaceutical manufacturing and advancing product quality.

    PubMed

    O'Connor, Thomas F; Yu, Lawrence X; Lee, Sau L

    2016-07-25

    Issues in product quality have produced recalls and caused drug shortages in United States (U.S.) in the past few years. These quality issues were often due to outdated manufacturing technologies and equipment as well as lack of an effective quality management system. To ensure consistent supply of safe, effective and high-quality drug products available to the patients, the U.S. Food and Drug Administration (FDA) supports modernizing pharmaceutical manufacturing for improvements in product quality. Specifically, five new initiatives are proposed here to achieve this goal. They include: (i) advancing regulatory science for pharmaceutical manufacturing; (ii) establishing a public-private institute for pharmaceutical manufacturing innovation; (iii) creating incentives for investment in the technological upgrade of manufacturing processes and facilities; (iv) leveraging external expertise for regulatory quality assessment of emerging technologies; and (v) promoting the international harmonization of approaches for expediting the global adoption of emerging technologies.

  6. Establishment of the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher E. Hull

    2006-09-30

    This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  7. ESTABLISHMENT OF THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2003-07-01

    Technical Progress Report describes progress made on the eight sub-projects awarded in the first year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of activity only.

  8. Mask manufacturing of advanced technology designs using multi-beam lithography (Part 1)

    NASA Astrophysics Data System (ADS)

    Green, Michael; Ham, Young; Dillon, Brian; Kasprowicz, Bryan; Hur, Ik Boum; Park, Joong Hee; Choi, Yohan; McMurran, Jeff; Kamberian, Henry; Chalom, Daniel; Klikovits, Jan; Jurkovic, Michal; Hudek, Peter

    2016-10-01

    As optical lithography is extended into 10nm and below nodes, advanced designs are becoming a key challenge for mask manufacturers. Techniques including advanced Optical Proximity Correction (OPC) and Inverse Lithography Technology (ILT) result in structures that pose a range of issues across the mask manufacturing process. Among the new challenges are continued shrinking Sub-Resolution Assist Features (SRAFs), curvilinear SRAFs, and other complex mask geometries that are counter-intuitive relative to the desired wafer pattern. Considerable capability improvements over current mask making methods are necessary to meet the new requirements particularly regarding minimum feature resolution and pattern fidelity. Advanced processes using the IMS Multi-beam Mask Writer (MBMW) are feasible solutions to these coming challenges. In this paper, we study one such process, characterizing mask manufacturing capability of 10nm and below structures with particular focus on minimum resolution and pattern fidelity.

  9. Enhanced bio-manufacturing through advanced multivariate statistical technologies.

    PubMed

    Martin, E B; Morris, A J

    2002-11-13

    The paper describes the interrogation of data, from a reaction vessel producing an active pharmaceutical ingredient (API), using advanced multivariate statistical techniques. Due to the limited number of batches available, data augmentation was used to increase the number of batches thereby enabling the extraction of more subtle process behaviour from the data. A second methodology investigated was that of multi-group modelling. This allowed between cluster variability to be removed, thus allowing attention to focus on within process variability. The paper describes how the different approaches enabled the realisation of a better understanding of the factors causing the onset of an impurity formation to be obtained as well demonstrating the power of multivariate statistical data analysis techniques to provide an enhanced understanding of the process.

  10. Advancing Measurement Science to Assess Monitoring, Diagnostics, and Prognostics for Manufacturing Robotics

    PubMed Central

    Qiao, Guixiu; Weiss, Brian A.

    2016-01-01

    Unexpected equipment downtime is a ‘pain point’ for manufacturers, especially in that this event usually translates to financial losses. To minimize this pain point, manufacturers are developing new health monitoring, diagnostic, prognostic, and maintenance (collectively known as prognostics and health management (PHM)) techniques to advance the state-of-the-art in their maintenance strategies. The manufacturing community has a wide-range of needs with respect to the advancement and integration of PHM technologies to enhance manufacturing robotic system capabilities. Numerous researchers, including personnel from the National Institute of Standards and Technology (NIST), have identified a broad landscape of barriers and challenges to advancing PHM technologies. One such challenge is the verification and validation of PHM technology through the development of performance metrics, test methods, reference datasets, and supporting tools. Besides documenting and presenting the research landscape, NIST personnel are actively researching PHM for robotics to promote the development of innovative sensing technology and prognostic decision algorithms and to produce a positional accuracy test method that emphasizes the identification of static and dynamic positional accuracy. The test method development will provide manufacturers with a methodology that will allow them to quickly assess the positional health of their robot systems along with supporting the verification and validation of PHM techniques for the robot system. PMID:28058172

  11. Advancing Measurement Science to Assess Monitoring, Diagnostics, and Prognostics for Manufacturing Robotics.

    PubMed

    Qiao, Guixiu; Weiss, Brian A

    2016-01-01

    Unexpected equipment downtime is a 'pain point' for manufacturers, especially in that this event usually translates to financial losses. To minimize this pain point, manufacturers are developing new health monitoring, diagnostic, prognostic, and maintenance (collectively known as prognostics and health management (PHM)) techniques to advance the state-of-the-art in their maintenance strategies. The manufacturing community has a wide-range of needs with respect to the advancement and integration of PHM technologies to enhance manufacturing robotic system capabilities. Numerous researchers, including personnel from the National Institute of Standards and Technology (NIST), have identified a broad landscape of barriers and challenges to advancing PHM technologies. One such challenge is the verification and validation of PHM technology through the development of performance metrics, test methods, reference datasets, and supporting tools. Besides documenting and presenting the research landscape, NIST personnel are actively researching PHM for robotics to promote the development of innovative sensing technology and prognostic decision algorithms and to produce a positional accuracy test method that emphasizes the identification of static and dynamic positional accuracy. The test method development will provide manufacturers with a methodology that will allow them to quickly assess the positional health of their robot systems along with supporting the verification and validation of PHM techniques for the robot system.

  12. Advanced Manufacturing Techniques Demonstrated for Fabricating Developmental Hardware

    NASA Technical Reports Server (NTRS)

    Redding, Chip

    2004-01-01

    NASA Glenn Research Center's Engineering Development Division has been working in support of innovative gas turbine engine systems under development by Glenn's Combustion Branch. These one-of-a-kind components require operation under extreme conditions. High-temperature ceramics were chosen for fabrication was because of the hostile operating environment. During the designing process, it became apparent that traditional machining techniques would not be adequate to produce the small, intricate features for the conceptual design, which was to be produced by stacking over a dozen thin layers with many small features that would then be aligned and bonded together into a one-piece unit. Instead of using traditional machining, we produced computer models in Pro/ENGINEER (Parametric Technology Corporation (PTC), Needham, MA) to the specifications of the research engineer. The computer models were exported in stereolithography standard (STL) format and used to produce full-size rapid prototype polymer models. These semi-opaque plastic models were used for visualization and design verification. The computer models also were exported in International Graphics Exchange Specification (IGES) format and sent to Glenn's Thermal/Fluids Design & Analysis Branch and Applied Structural Mechanics Branch for profiling heat transfer and mechanical strength analysis.

  13. A novel precision face grinder for advanced optic manufacture

    NASA Astrophysics Data System (ADS)

    Guo, Y.; Peng, Y.; Wang, Z.; Yang, W.; Bi, G.; Ke, X.; Lin, X.

    2010-10-01

    In this paper, a large-scale NC precision face grinding machine is developed. This grinding machine can be used to the precision machining of brittle materials. The base and the machine body are independent and the whole structure is configured as a "T" type. The vertical column is seat onto the machine body at the middle center part through a double of precision lead rails. The grinding wheel is driven with a hydraulic dynamic and static spindle. The worktable is supported with a novel split thin film throttle hydrostatic lead rails. Each of motion-axis of the grinding machine is equipped with a Heidenhain absolute linear encoder, and then a closed feedback control system is formed with the adopted Fanuc 0i-MD NC system. The machine is capable of machining extremely flat surfaces on workpiece up to 800mmx600mm. The maximums load bearing of the work table is 620Kg. Furthermore, the roughness of the machined surfaces should be smooth (Ra<50nm-100nm), and the form accuracy less than 2μm (+/-1μm)/200x200mm. After the assembly and debugging of the surface grinding machine, the worktable surface has been self-ground with 60# grinding wheel and the form accuracy is 3μm/600mm×800mm. Then the grinding experiment was conduct on a BK7 flat optic glass element (400mmx250mm) and a ceramic disc (Φ100mm) with 60# grinding wheel, and the measuring results show the surface roughness and the form accuracy of the optic glass device are 0.07μm and 1.56μm/200x200mm, and these of the ceramic disc are 0.52μm and 1.28μm respectively.

  14. Advanced carbon manufacturing for energy and biological applications

    NASA Astrophysics Data System (ADS)

    Turon Teixidor, Genis

    The science of miniaturization has experienced revolutionary advances during the last decades, witnessing the development of the Integrated Circuit and the emergence of MEMS and Nanotechnology. Particularly, MEMS technology has pioneered the use of non-traditional materials in microfabrication by including polymers, ceramics and composites to the well known list of metals and semiconductors. One of the latest additions to this set of materials is carbon, which represents a very important inclusion given its significance in electrochemical energy conversion systems and in applications where it is used as sensor probe material. For these applications, carbon is optimal in several counts: It has a wide electrochemical stability window, good electrical and thermal conductivity, high corrosion resistance and mechanical stability, and is available in high purity at a low cost. Furthermore carbon is biocompatible. This thesis presents several microfabricated devices that take advantage of these properties. The thesis has two clearly differentiated parts. In the first one, applications of micromachined carbon in the field of energy conversion and energy storage are presented. These applications include lithium ion micro batteries and the development of new carbon electrodes with fractal geometries. In the second part, the focus shifts to biological applications. First, the study of the interaction of living cells with micromachined carbon is presented, followed by the description of a sensor based on interdigitated nano-electrode arrays, and finally the development of the new instrumentation needed to address arrays of carbon electrodes, a multiplexed potentiostat. The underlying theme that connects all these seemingly different topics is the use of carbon microfabrication techniques in electrochemical systems.

  15. Isotope separation and advanced manufacturing technology. Volume 2, No. 2, Semiannual report, April--September 1993

    SciTech Connect

    Kan, Tehmanu; Carpenter, J.

    1993-12-31

    This is the second issue of a semiannual report for the Isotope Separation and Advanced Manufacturing (ISAM) Technology Program at Lawrence Livermore National Laboratory. Primary objectives of the ISAM Program include: the Uranium Atomic Vapor Laser Isotope Separation (U-AVLIS) process, and advanced manufacturing technologies which include industrial laser materials processing and new manufacturing technologies for uranium, plutonium, and other strategically important materials in support of DOE and other national applications. Topics included in this issue are: production plant product system conceptual design, development and operation of a solid-state switch for thyratron replacement, high-performance optical components for high average power laser systems, use of diode laser absorption spectroscopy for control of uranium vaporization rates, a two-dimensional time dependent hydrodynamical ion extraction model, and design of a formaldehyde photodissociation process for carbon and oxygen isotope separation.

  16. Opportunities for the Advancement of Home Economists in the Food Manufacturing Industry.

    ERIC Educational Resources Information Center

    Michael, Carol M.

    1999-01-01

    Responses from 133 home economists employed by food manufacturers showed that many have high aspirations but few have advanced to upper-level management. Factors influencing business success included years with company and in career and mentor/sponsor relationships. Many felt limited by lack of business background and the service orientation of…

  17. National Skill Standards for Advanced High Performance Manufacturing. Version 2.1.

    ERIC Educational Resources Information Center

    National Coalition for Advanced Manufacturing, Washington, DC.

    This document presents and discusses the national skill standards for advanced high-performance manufacturing that were developed during a project that was commissioned by the U.S. Department of Education. The introduction explains the need for national skill standards. Discussed in the next three sections are the following: benefits of national…

  18. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2004-05-12

    This Technical Progress Report describes progress made on the seventeen subprojects awarded in the first year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of project activity only. The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium--Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno--that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation (2) Solid-liquid separation (3) Chemical/Biological Extraction (4) Modeling and Control, and (5) Environmental Control.

  19. Center for Technology for Advanced Scientific Component Software (TASCS)

    SciTech Connect

    Damevski, Kostadin

    2009-03-30

    A resounding success of the Scientific Discover through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedened computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative hig-performance scientific computing.

  20. Center for Advanced Signal and Imaging Sciences Workshop 2004

    SciTech Connect

    McClellan, J H; Carrano, C; Poyneer, L; Palmer, D; Baker, K; Chen, D; London, R; Weinert, G; Brase, J; Paglieroni, D; Lopez, A; Grant, C W; Wright, W; Burke, M; Miller, W O; DeTeresa, S; White, D; Toeppen, J; Haugen, P; Kamath, C; Nguyen, T; Manay, S; Newsam, S; Cantu-Paz, E; Pao, H; Chang, J; Chambers, D; Leach, R; Paulson, C; Romero, C E; Spiridon, A; Vigars, M; Welsh, P; Zumstein, J; Romero, K; Oppenheim, A; Harris, D B; Dowla, F; Brown, C G; Clark, G A; Ong, M M; Clance, T J; Kegelmeyer, l M; Benzuijen, M; Bliss, E; Burkhart, S; Conder, A; Daveler, S; Ferguson, W; Glenn, S; Liebman, J; Norton, M; Prasad, R; Salmon, T; Kegelmeyer, L M; Hafiz, O; Cheung, S; Fodor, I; Aufderheide, M B; Bary, A; Martz, Jr., H E; Burke, M W; Benson, S; Fisher, K A; Quarry, M J

    2004-11-15

    Welcome to the Eleventh Annual C.A.S.I.S. Workshop, a yearly event at the Lawrence Livermore National Laboratory, presented by the Center for Advanced Signal & Image Sciences, or CASIS, and sponsored by the LLNL Engineering Directorate. Every November for the last 10 years we have convened a diverse set of engineering and scientific talent to share their work in signal processing, imaging, communications, controls, along with associated fields of mathematics, statistics, and computing sciences. This year is no exception, with sessions in Adaptive Optics, Applied Imaging, Scientific Data Mining, Electromagnetic Image and Signal Processing, Applied Signal Processing, National Ignition Facility (NIF) Imaging, and Nondestructive Characterization.

  1. Oklahoma State University proposed Advanced Technology Research Center. Environmental Assessment

    SciTech Connect

    1995-06-01

    The Department of Energy (DOE) has prepared an Environmental Assessment (EA) evaluating the construction and equipping of the proposed Advanced Technology Research Center (ATRC) at Oklahoma State University (OSU) in Stillwater, Oklahoma. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement is not required.

  2. Innovative and Efficient Manufacturing Technologies for Highly Advanced Composite Pressure Vessels

    NASA Astrophysics Data System (ADS)

    Hock, Birte; Regnet, Martin; Bickelaier, Stefan; Henne, Florian; Sause, Markus G. R.; Schmidt, Thomas; Geiss, Gunter

    2014-06-01

    The currently ongoing development project at MT Aerospace (MTA) deals with a cost efficient manufacturing process for space structures. Thermoplastic fibre placement, which was identified as one of the most forward-looking technologies, promises advantages such as shorter cycle times and a high level of automation. In addition to the manufacturing method, research activities on non-destructive inspection methods and on acoustic emission analysis are performed. The analysis of the components will also be improved using advanced modelling approaches. The capability of the processes and methods will be shown on the basis of a scaled solid rocket motor casing.

  3. Present Status and Future Growth of Advanced Maintenance Technology and Strategy in US Manufacturing

    PubMed Central

    Jin, Xiaoning; Weiss, Brian A.; Siegel, David; Lee, Jay

    2016-01-01

    The goals of this paper are to 1) examine the current practices of diagnostics, prognostics, and maintenance employed by United States (U.S.) manufacturers to achieve productivity and quality targets and 2) to understand the present level of maintenance technologies and strategies that are being incorporated into these practices. A study is performed to contrast the impact of various industry-specific factors on the effectiveness and profitability of the implementation of prognostics and health management technologies, and maintenance strategies using both surveys and case studies on a sample of U.S. manufacturing firms ranging from small to mid-sized enterprises (SMEs) to large-sized manufacturing enterprises in various industries. The results obtained provide important insights on the different impacts of specific factors on the successful adoption of these technologies between SMEs and large manufacturing enterprises. The varying degrees of success with respect to current maintenance programs highlight the opportunity for larger manufacturers to improve maintenance practices and consider the use of advanced prognostics and health management (PHM) technology. This paper also provides the existing gaps, barriers, future trends, and roadmaps for manufacturing PHM technology and maintenance strategy. PMID:28058173

  4. Present Status and Future Growth of Advanced Maintenance Technology and Strategy in US Manufacturing.

    PubMed

    Jin, Xiaoning; Weiss, Brian A; Siegel, David; Lee, Jay

    2016-01-01

    The goals of this paper are to 1) examine the current practices of diagnostics, prognostics, and maintenance employed by United States (U.S.) manufacturers to achieve productivity and quality targets and 2) to understand the present level of maintenance technologies and strategies that are being incorporated into these practices. A study is performed to contrast the impact of various industry-specific factors on the effectiveness and profitability of the implementation of prognostics and health management technologies, and maintenance strategies using both surveys and case studies on a sample of U.S. manufacturing firms ranging from small to mid-sized enterprises (SMEs) to large-sized manufacturing enterprises in various industries. The results obtained provide important insights on the different impacts of specific factors on the successful adoption of these technologies between SMEs and large manufacturing enterprises. The varying degrees of success with respect to current maintenance programs highlight the opportunity for larger manufacturers to improve maintenance practices and consider the use of advanced prognostics and health management (PHM) technology. This paper also provides the existing gaps, barriers, future trends, and roadmaps for manufacturing PHM technology and maintenance strategy.

  5. Advanced Stirling Technology Development at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Shaltens, Richard K.; Wong, Wayne A.

    2007-01-01

    The NASA Glenn Research Center has been developing advanced energy-conversion technologies for use with both radioisotope power systems and fission surface power systems for many decades. Under NASA's Science Mission Directorate, Planetary Science Theme, Technology Program, Glenn is developing the next generation of advanced Stirling convertors (ASCs) for use in the Department of Energy/Lockheed Martin Advanced Stirling Radioisotope Generator (ASRG). The next-generation power-conversion technologies require high efficiency and high specific power (watts electric per kilogram) to meet future mission requirements to use less of the Department of Energy's plutonium-fueled general-purpose heat source modules and reduce system mass. Important goals include long-life (greater than 14-yr) reliability and scalability so that these systems can be considered for a variety of future applications and missions including outer-planet missions and continual operation on the surface of Mars. This paper provides an update of the history and status of the ASC being developed for Glenn by Sunpower Inc. of Athens, Ohio.

  6. Center for Center for Technology for Advanced Scientific Component Software (TASCS)

    SciTech Connect

    Kostadin, Damevski

    2015-01-25

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS)1 tackles these these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  7. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-01-20

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/Biological Extraction; (4) Modeling and Control; and (5) Environmental Control.

  8. Latest Development in Advanced Sensors at Kennedy Space Center (KSC)

    NASA Technical Reports Server (NTRS)

    Perotti, Jose M.; Eckhoff, Anthony J.; Voska, N. (Technical Monitor)

    2002-01-01

    Inexpensive space transportation system must be developed in order to make spaceflight more affordable. To achieve this goal, there is a need to develop inexpensive smart sensors to allow autonomous checking of the health of the vehicle and associated ground support equipment, warn technicians or operators of an impending problem and facilitate rapid vehicle pre-launch operations. The Transducers and Data Acquisition group at Kennedy Space Center has initiated an effort to study, research, develop and prototype inexpensive smart sensors to accomplish these goals. Several technological challenges are being investigated and integrated in this project multi-discipline sensors; self-calibration, health self-diagnosis capabilities embedded in sensors; advanced data acquisition systems with failure prediction algorithms and failure correction (self-healing) capabilities.

  9. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher Hull

    2009-10-31

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium -- Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno - that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/biological extraction; (4) Modeling and control; and (5) Environmental control. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed by category, along with brief abstracts of their aims and objectives.

  10. Recent advance on design and manufacturing of composite anisogrid structures for space launchers

    NASA Astrophysics Data System (ADS)

    Totaro, G.; De Nicola, F.

    2012-12-01

    Anisogrid composite shells have been developed and applied since the eighties by the Russian technology aiming at critical weight structures for space launchers, as interstages and cone adapters. The manufacturing process commonly applied is based on the wet filament winding. The paper concerns with some developments of design and manufacturing recently performed at the Italian Aerospace Research Center on a cylindrical structural model representative of this kind of structures. The framework of preliminary design is improved by introducing the concept of suboptimal configuration in order to match the stiffness requirement of the shell and minimise the mass, in conjunction with the typical strength constraints. The undertaken manufacturing process is based on dry robotic winding for the lattice structure and for the outer skin, with the aid of usual rubber tooling and new devices for the automated deposition strategy. Resin infusion under vacuum bag and co-cure of the system of ribs and skin is finally applied out-of-autoclave, with the aid of a heated mandrel. With such approach an interstage structural model (scale factor 1:1.5) has been designed, manufactured and tested. Design requirements and loads refer to a typical space launcher whose baseline configuration is made in aluminium. The global mechanical test of the manufactured structure has confirmed the expected high structural performance. The possibility to reach substantial weight savings in comparison with the aluminium benchmark has been fully demonstrated.

  11. Advanced Stirling Convertor Testing at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Oriti, Salvatore M.; Blaze, Gina M.

    2007-01-01

    The U.S. Department of Energy (DOE), Lockheed Martin Space Systems (LMSS), Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science and exploration missions. This generator will make use of the free-piston Stirling convertors to achieve higher conversion efficiency than currently available alternatives. The ASRG will utilize two Advanced Stirling Convertors (ASC) to convert thermal energy from a radioisotope heat source to electricity. NASA GRC has initiated several experiments to demonstrate the functionality of the ASC, including: in-air extended operation, thermal vacuum extended operation, and ASRG simulation for mobile applications. The in-air and thermal vacuum test articles are intended to provide convertor performance data over an extended operating time. These test articles mimic some features of the ASRG without the requirement of low system mass. Operation in thermal vacuum adds the element of simulating deep space. This test article is being used to gather convertor performance and thermal data in a relevant environment. The ASRG simulator was designed to incorporate a minimum amount of support equipment, allowing integration onto devices powered directly by the convertors, such as a rover. This paper discusses the design, fabrication, and implementation of these experiments.

  12. Center for Advanced Energy Studies (CAES) Strategic Plan

    SciTech Connect

    Kevin Kostelnik; Keith Perry

    2007-07-01

    Twenty-first century energy challenges include demand growth, national energy security, and global climate protection. The Center for Advanced Energy Studies (CAES) is a public/private partnership between the State of Idaho and its academic research institutions, the federal government through the U.S. Department of Energy (DOE) and the Idaho National Laboratory (INL) managed by the Battelle Energy Alliance (BEA). CAES serves to advance energy security for our nation by expanding the educational opportunities at the Idaho universities in energy-related areas, creating new capabilities within its member institutions, and delivering technological innovations leading to technology-based economic development for the intermountain region. CAES has developed this strategic plan based on the Balanced Scorecard approach. A Strategy Map (Section 7) summarizes the CAES vision, mission, customers, and strategic objectives. Identified strategic objectives encompass specific outcomes related to three main areas: Research, Education, and Policy. Technical capabilities and critical enablers needed to support these objectives are also identified. This CAES strategic plan aligns with and supports the strategic objectives of the four CAES institutions. Implementation actions are also presented which will be used to monitor progress towards fulfilling these objectives.

  13. An Analysis of Collaborative Technology Advancements Achieved through the Center for Network Innovation and Experimentation

    DTIC Science & Technology

    2008-12-01

    COLLABORATIVE TECHNOLOGY ADVANCEMENTS ACHIEVED THROUGH THE CENTER FOR NETWORK INNOVATION AND EXPERIMENTATION by Eric L. Quarles December 2008...Advancements Achieved through the Center for Network Innovation and Experimentation 6. AUTHOR(S) Eric L. Quarles 5. FUNDING NUMBERS 7...cycles which the members of the Naval Postgraduate School Center for Network Innovation and Experimentation (CENETIX) participate. These experiments

  14. The advanced manufacturing science and technology program. FY 95 Annual Report

    SciTech Connect

    Hill, J.

    1996-03-01

    This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST committee formed a team to write a roadmap and serve as a partnering technical consultant. To date, the roadmaps have been completed for each of the four areas. The Casting Technology and Polymer Aging teams are negotiating with specific potential partners now, at the close of the fiscal year. For each focus area we have created a list of existing collaborations and other ongoing partnering activities. In early Fiscal Year 1996, we will continue to develop partnerships in these four areas. Los Alamos National Laboratory instituted the tactical goals for industrial partnering to focus our institutional resources on partnerships that enhance core competencies and capabilities required to meet our national security mission of reducing the nuclear danger. The second industry sector targeted by Tactical Goal 6 was the chemical industry. Tactical Goal 6 is championed by the Industrial Partnership Office.

  15. Practical Education Support to Foster Engineers at Manufacturing and Engineering Design Center in Muroran Institute of Technology

    NASA Astrophysics Data System (ADS)

    Kazama, Toshiharu; Hanajima, Naohiko; Shimizu, Kazumichi; Satoh, Kohki

    To foster engineers with creative power, Muroran Institute of Technology established Manufacturing and Engineering Design Center (MEDeC) that concentrates on Monozukuri. MEDeC consists of three project groups : i) Education Support Group provides educational support for practical training classes on and off campus and PDCA (plan-do-check-action) -conscious engineering design education related to Monozukuri ; ii) Fundamental Manufacturing Research Group carries out nurture research into fundamental and innovative technology of machining and manufacturing, and iii) Regional Cooperation Group coordinates the activities in cooperation with bureau, schools and industries in and around Muroran City. MEDeC has a fully integrated collection of machine tools and hand tools for manufacturing, an atelier, a tatara workplace, implements for measurement and related equipment designed for practically teaching state-of-the-practice manufacturing methods.

  16. Advanced Stirling Convertor Testing at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Poriti, Sal

    2010-01-01

    The NASA Glenn Research Center (GRC) has been testing high-efficiency free-piston Stirling convertors for potential use in radioisotope power systems (RPSs) since 1999. The current effort is in support of the Advanced Stirling Radioisotope Generator (ASRG), which is being developed by the U.S. Department of Energy (DOE), Lockheed Martin Space Systems Company (LMSSC), Sunpower, Inc., and the NASA GRC. This generator would use two high-efficiency Advanced Stirling Convertors (ASCs) to convert thermal energy from a radioisotope heat source into electricity. As reliability is paramount to a RPS capable of providing spacecraft power for potential multi-year missions, GRC provides direct technology support to the ASRG flight project in the areas of reliability, convertor and generator testing, high-temperature materials, structures, modeling and analysis, organics, structural dynamics, electromagnetic interference (EMI), and permanent magnets to reduce risk and enhance reliability of the convertor as this technology transitions toward flight status. Convertor and generator testing is carried out in short- and long-duration tests designed to characterize convertor performance when subjected to environments intended to simulate launch and space conditions. Long duration testing is intended to baseline performance and observe any performance degradation over the life of the test. Testing involves developing support hardware that enables 24/7 unattended operation and data collection. GRC currently has 14 Stirling convertors under unattended extended operation testing, including two operating in the ASRG Engineering Unit (ASRG-EU). Test data and high-temperature support hardware are discussed for ongoing and future ASC tests with emphasis on the ASC-E and ASC-E2.

  17. Center for Advanced Biofuel Systems (CABS) Final Report

    SciTech Connect

    Kutchan, Toni M.

    2015-12-02

    One of the great challenges facing current and future generations is how to meet growing energy demands in an environmentally sustainable manner. Renewable energy sources, including wind, geothermal, solar, hydroelectric, and biofuel energy systems, are rapidly being developed as sustainable alternatives to fossil fuels. Biofuels are particularly attractive to the U.S., given its vast agricultural resources. The first generation of biofuel systems was based on fermentation of sugars to produce ethanol, typically from food crops. Subsequent generations of biofuel systems, including those included in the CABS project, will build upon the experiences learned from those early research results and will have improved production efficiencies, reduced environmental impacts and decreased reliance on food crops. Thermodynamic models predict that the next generations of biofuel systems will yield three- to five-fold more recoverable energy products. To address the technological challenges necessary to develop enhanced biofuel systems, greater understanding of the non-equilibrium processes involved in solar energy conversion and the channeling of reduced carbon into biofuel products must be developed. The objective of the proposed Center for Advanced Biofuel Systems (CABS) was to increase the thermodynamic and kinetic efficiency of select plant- and algal-based fuel production systems using rational metabolic engineering approaches grounded in modern systems biology. The overall strategy was to increase the efficiency of solar energy conversion into oils and other specialty biofuel components by channeling metabolic flux toward products using advanced catalysts and sensible design:1) employing novel protein catalysts that increase the thermodynamic and kinetic efficiencies of photosynthesis and oil biosynthesis; 2) engineering metabolic networks to enhance acetyl-CoA production and its channeling towards lipid synthesis; and 3) engineering new metabolic networks for the

  18. Advanced manufacturing rules check (MRC) for fully automated assessment of complex reticle designs: Part II

    NASA Astrophysics Data System (ADS)

    Straub, J. A.; Aguilar, D.; Buck, P. D.; Dawkins, D.; Gladhill, R.; Nolke, S.; Riddick, J.

    2006-10-01

    Advanced electronic design automation (EDA) tools, with their simulation, modeling, design rule checking, and optical proximity correction capabilities, have facilitated the improvement of first pass wafer yields. While the data produced by these tools may have been processed for optimal wafer manufacturing, it is possible for the same data to be far from ideal for photomask manufacturing, particularly at lithography and inspection stages, resulting in production delays and increased costs. The same EDA tools used to produce the data can be used to detect potential problems for photomask manufacturing in the data. In the previous paper, it was shown how photomask MRC is used to uncover data related problems prior to automated defect inspection. It was demonstrated how jobs which are likely to have problems at inspection could be identified and separated from those which are not. The use of photomask MRC in production was shown to reduce time lost to aborted runs and troubleshooting due to data issues. In this paper, the effectiveness of this photomask MRC program in a high volume photomask factory over the course of a year as applied to more than ten thousand jobs will be shown. Statistics on the results of the MRC runs will be presented along with the associated impact to the automated defect inspection process. Common design problems will be shown as well as their impact to mask manufacturing throughput and productivity. Finally, solutions to the most common and most severe problems will be offered and discussed.

  19. New Paradigms in International University/Industry/Government Cooperation. Canada-China Collaboration in Advanced Manufacturing Technologies.

    ERIC Educational Resources Information Center

    Bulgak, Akif Asil; Liquan, He

    1996-01-01

    A Chinese university and a Canadian university collaborated on an advanced manufacturing technologies project designed to address human resource development needs in China. The project featured university/industry/government partnership and attention to environmental issues. (SK)

  20. 77 FR 37422 - National Center for Advancing Translational Sciences; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Panel; Division of Comparative Medicine Peer Review Meeting; Office of Research Infrastructure Programs... Center for Advancing Translational Sciences, National Institutes of Health, 6701 Democracy Blvd., Dem....

  1. Advanced manufacturing technology effectiveness: A review of literature and some issues

    NASA Astrophysics Data System (ADS)

    Goyal, Sanjeev; Grover, Sandeep

    2012-09-01

    Advanced manufacturing technology (AMT) provides advantages to manufacturing managers in terms of flexibility, quality, reduced delivery times, and global competitiveness. Although a large number of publications had presented the importance of this technology, only a few had delved into related literature review. Considering the importance of this technology and the recent contributions by various authors, the present paper conducts a more comprehensive review. Literature was reviewed in a way that will help researchers, academicians, and practitioners to take a closer look at the implementation, evaluation, and justification of the AMT. The authors reviewed various papers, proposed a different classification scheme, and identified certain gaps that will provide hints for further research in AMT management.

  2. An experiment in remote manufacturing using the advanced communications technology satellite

    NASA Technical Reports Server (NTRS)

    Tsatsoulis, Costas; Frost, Victor

    1991-01-01

    The goal of the completed project was to develop an experiment in remote manufacturing that would use the capabilities of the ACTS satellite. A set of possible experiments that could be performed using the Advanced Communications Technology Satellite (ACTS), and which would perform remote manufacturing using a laser cutter and an integrated circuit testing machine are described in detail. The proposed design is shown to be a feasible solution to the offered problem and it takes into consideration the constraints that were placed on the experiment. In addition, we have developed two more experiments that are included in this report: backup of rural telecommunication networks, and remote use of Synthetic Aperture Radar (SAR) data analysis for on-site collection of glacier scattering data in the Antarctic.

  3. Apparel Manufacture

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Marshall Space Flight Center teamed with the University of Alabama in Huntsville (UAH) in 1989 on a program involving development of advanced simulation software. Concurrently, the State of Alabama chartered UAH to conduct a technology advancement program in support of the state's apparel manufacturers. In 1992, under contract to Marshall, UAH developed an apparel-specific software package that allows manufacturers to design and analyze modules without making an actual investment -- it functions on ordinary PC equipment. By 1995, Marshall had responded to requests for the package from more than 400 companies in 36 states; some of which reported savings up to $2 million. The National Garment Company of Missouri, for example, uses the system to design and balance a modular line before committing to expensive hardware; for setting up sewing lines; and for determining the composition of a new team.

  4. Advanced manufacturing development of a composite empennage component for L-1011 aircraft

    NASA Technical Reports Server (NTRS)

    Alva, T.; Henkel, J.; Johnson, R.; Carll, B.; Jackson, A.; Mosesian, B.; Brozovic, R.; Obrien, R.; Eudaily, R.

    1982-01-01

    This is the final report of technical work conducted during the fourth phase of a multiphase program having the objective of the design, development and flight evaluation of an advanced composite empennage component manufactured in a production environment at a cost competitive with those of its metal counterpart, and at a weight savings of at least 20 percent. The empennage component selected for this program is the vertical fin box of the L-1011 aircraft. The box structure extends from the fuselage production joint to the tip rib and includes front and rear spars. During Phase 4 of the program, production quality tooling was designed and manufactured to produce three sets of covers, ribs, spars, miscellaneous parts, and subassemblies to assemble three complete ACVF units. Recurring and nonrecurring cost data were compiled and documented in the updated producibility/design to cost plan. Nondestruct inspections, quality control tests, and quality acceptance tests were performed in accordance with the quality assurance plan and the structural integrity control plan. Records were maintained to provide traceability of material and parts throughout the manufacturing development phase. It was also determined that additional tooling would not be required to support the current and projected L-1011 production rate.

  5. 78 FR 76634 - National Center for Advancing Translational Sciences; Notice of Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... 20892. Contact Person: Danilo A Tagle, Ph.D., Executive Secretary, National Center for Advancing Translational Sciences, 1 Democracy Plaza, Room 992, Bethesda, MD 20892, 301-594-8064, Danilo.Tagle@nih.gov.... Contact Person: Danilo A Tagle, Ph.D., Executive Secretary, National Center for Advancing...

  6. Women's Center Volunteer Intern Program: Building Community While Advancing Social and Gender Justice

    ERIC Educational Resources Information Center

    Murray, Margaret A.; Vlasnik, Amber L.

    2015-01-01

    This program description explores the purpose, structure, activities, and outcomes of the volunteer intern program at the Wright State University Women's Center. Designed to create meaningful, hands-on learning experiences for students and to advance the center's mission, the volunteer intern program builds community while advancing social and…

  7. Reduced toxicity polyester resins and microvascular pre-preg tapes for advanced composites manufacturing

    NASA Astrophysics Data System (ADS)

    Poillucci, Richard

    Advanced composites manufacturing broadly encapsulates topics ranging from matrix chemistries to automated machines that lay-up fiber-reinforced materials. Environmental regulations are stimulating research to reduce matrix resin formulation toxicity. At present, composites fabricated with polyester resins expose workers to the risk of contact with and inhalation of styrene monomer, which is a potential carcinogen, neurotoxin, and respiratory irritant. The first primary goal of this thesis is to reduce the toxicity associated with polyester resins by: (1) identification of potential monomers to replace styrene, (2) determination of monomer solubility within the polyester, and (3) investigation of approaches to rapidly screen a large resin composition parameter space. Monomers are identified based on their ability to react with polyester and their toxicity as determined by the Globally Harmonized System (GHS) and a green screen method. Solubilities were determined by the Hoftyzer -- Van Krevelen method, Hansen solubility parameter database, and experimental mixing of monomers. A combinatorial microfluidic mixing device is designed and tested to obtain distinct resin compositions from two input chemistries. The push for safer materials is complemented by a thrust for multifunctional composites. The second primary goal of this thesis is to design and implement the manufacture of sacrificial fiber materials suitable for use in automated fiber placement of microvascaular multifunctional composites. Two key advancements are required to achieve this goal: (1) development of a roll-to-roll method to place sacrificial fibers onto carbon fiber pre-preg tape; and (2) demonstration of feasible manufacture of microvascular carbon fiber plates with automated fiber placement. An automated method for placing sacrificial fibers onto carbon fiber tapes is designed and a prototype implemented. Carbon fiber tows with manual placement of sacrificial fibers is implemented within an

  8. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2003-11-15

    The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (a) Solid-solid separation (b) Solid-liquid separation (c) Chemical/Biological Extraction (d) Modeling and Control, and (e) Environmental Control. Distribution of funds is being handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. The first of these solicitations, referred to as the CAST II-Round 1 RFP, was issued on October 28, 2002. Thirty-eight proposals were received by the December 10, 2002 deadline for this RFP-eleven (11) Solid-Solid Separation, seven (7) Solid-Liquid Separation, ten (10) Chemical/Biological Extraction, six (6) Modeling & Control and four (4) Environmental Control. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. This process took some 7 months to complete but 17 projects (one joint) were in place at the constituent universities (three at Virginia Tech, two at West Virginia University, three at University of Kentucky

  9. Driving forces of heavy metal changes in agricultural soils in a typical manufacturing center.

    PubMed

    Qiu, Menglong; Li, Fangbai; Wang, Qi; Chen, Junjian; Yang, Guoyi; Liu, Liming

    2015-05-01

    Heavy metal concentrations in 2002 and 2012 in agricultural soils in Dongguan, a manufacturing center in southern China, were analyzed to determine the impact of rapid economic development on soil pollution. The level of pollution was assessed using the Nemerow synthetic pollution index (NPI), and its changing characteristics and driving forces were analyzed using multivariate statistical and geostatistical methods. The results indicate that the mean NPI was 0.79 in 2002 and 0.84 in 2012, which indicates aggravated heavy metal contamination in the agricultural soils. The concentrations of Cd and Zn increased 54.7 and 20.8 %, respectively, whereas Hg and Pb decreased 35.3 and 24.5 %, respectively. Cr, As, Cu, and Ni remained relatively stable. The Hg and Cd concentrations were highly correlated with soil types (P < 0.01), the secondary industrial output per unit of land (P < 0.01), proportion of cereal fields (P < 0.01), proportion of vegetable fields (P < 0.01), population density (P < 0.05), and road density (P < 0.05). The Pb and As concentrations were greatly influenced by soil types (P < 0.01), river density (P < 0.01), fertilizer rate (P < 0.01), and road density (P < 0.05). Cr, Zn, Cu, and Ni concentrations were primarily driven by soil types (P < 0.01), river density (P < 0.01), and fertilizer rate (P < 0.05).

  10. Military trauma training at civilian centers: a decade of advancements.

    PubMed

    Thorson, Chad M; Dubose, Joseph J; Rhee, Peter; Knuth, Thomas E; Dorlac, Warren C; Bailey, Jeffrey A; Garcia, George D; Ryan, Mark L; Van Haren, Robert M; Proctor, Kenneth G

    2012-12-01

    In the late 1990s, a Department of Defense subcommittee screened more than 100 civilian trauma centers according to the number of admissions, percentage of penetrating trauma, and institutional interest in relation to the specific training missions of each of the three service branches. By the end of 2001, the Army started a program at University of Miami/Ryder Trauma Center, the Navy began a similar program at University of Southern California/Los Angeles County Medical Center, and the Air Force initiated three Centers for the Sustainment of Trauma and Readiness Skills (C-STARS) at busy academic medical centers: R. Adams Cowley Shock Trauma Center at the University of Maryland (C-STARS Baltimore), Saint Louis University (C-STARS St. Louis), and The University Hospital/University of Cincinnati (C-STARS Cincinnati). Each center focuses on three key areas, didactic training, state-of-the-art simulation and expeditionary equipment training, as well as actual clinical experience in the acute management of trauma patients. Each is integral to delivering lifesaving combat casualty care in theater. Initially, there were growing pains and the struggle to develop an effective curriculum in a short period. With the foresight of each trauma training center director and a dynamic exchange of information with civilian trauma leaders and frontline war fighters, there has been a continuous evolution and improvement of each center's curriculum. Now, it is clear that the longest military conflict in US history and the first of the 21st century has led to numerous innovations in cutting edge trauma training on a comprehensive array of topics. This report provides an overview of the decade-long evolutionary process in providing the highest-quality medical care for our injured heroes.

  11. Manufactured Homes as Affordable Housing in Rural Areas. Rural Information Center Publication Series, No. 5.

    ERIC Educational Resources Information Center

    Czerniak, Robert, Comp.

    This bibliography includes citations of approximately 60 books and articles pertaining to manufactured housing or "mobile homes," an important segment of the national housing industry. The availability of manufactured homes for low and moderate income groups is significant in light of skyrocketing new-housing costs. The South leads the nation with…

  12. Isotope Separation and Advanced Manufacturing Technology. ISAM semiannual report, Volume 3, Number 1, October 1993--March 1994

    SciTech Connect

    Carpenter, J.; Kan, T.

    1994-10-01

    This is the fourth issue of a semiannual report for the Isotope Separation and Advanced Materials Manufacturing (ISAM) Technology Program at Lawrence Livermore National Laboratory. Primary objectives include: (I) the Uranium Atomic Vapor Laser Isotope Separation (UAVLIS) process, which is being developed and prepared for deployment as an advanced uranium enrichment capability; (II) Advanced manufacturing technologies, which include industrial laser and E-beam material processing and new manufacturing technologies for uranium, plutonium, and other strategically important materials in support of DOE and other national applications. This report features progress in the ISAM Program from October 1993 through March 1994. Selected papers were indexed separately for inclusion in the Energy Science and Technology Database.

  13. Development of Advanced Manufacturing Methods for Warm White LEDs for General Lighting

    SciTech Connect

    Deshpande, Anirudha; Kolodin, Boris; Jacob, Cherian; Chowdhury, Ashfaqul; Kuenzler, Glenn; Sater, Karen; Aesram, Danny; Glaettli, Steven; Gallagher, Brian; Langer, Paul; Setlur, Anant; Beers, Bill

    2012-03-31

    GE Lighting Solutions will develop precise and efficient manufacturing techniques for the “remote phosphor” platform of warm-white LED products. In volume, this will be demonstrated to drive significant materials, labor and capital productivity to achieve a maximum possible 53% reduction in overall cost. In addition, the typical total color variation for these white LEDs in production will be well within the ANSI bins and as low as a 4-step MacAdam ellipse centered on the black body curve. Achievement of both of these objectives will be demonstrated while meeting a performance target of > 75 lm/W for a warm-white LED and a reliability target of <30% lumen drop / <2-step MacAdam ellipse shift, estimated over 50,000 hrs.

  14. Advanced surface chemical analysis of continuously manufactured drug loaded composite pellets.

    PubMed

    Hossain, Akter; Nandi, Uttom; Fule, Ritesh; Nokhodchi, Ali; Maniruzzaman, Mohammed

    2017-04-15

    The aim of the present study was to develop and characterise polymeric composite pellets by means of continuous melt extrusion techniques. Powder blends of a steroid hormone (SH) as a model drug and either ethyl cellulose (EC N10 and EC P7 grades) or hydroxypropyl methylcellulose (HPMC AS grade) as polymeric carrier were extruded using a Pharma 11mm twin screw extruder in a continuous mode of operation to manufacture extruded composite pellets of 1mm length. Molecular modelling study using commercial Gaussian 09 software outlined a possible drug-polymer interaction in the molecular level to develop solid dispersions of the drug in the pellets. Solid-state analysis conducted via a differential scanning calorimetry (DSC), hot stage microscopy (HSM) and X-ray powder diffraction (XRPD) analyses revealed the amorphous state of the drug in the polymer matrices. Surface analysis using SEM/energy dispersive X-ray (EDX) of the produced pellets arguably showed a homogenous distribution of the C and O atoms in the pellet matrices. Moreover, advanced chemical surface analysis conducted via atomic force microscopy (AFM) showed a homogenous phase system having the drug molecule dispersed onto the amorphous matrices while Raman mapping confirmed the homogenous single-phase drug distribution in the manufactured composite pellets. Such composite pellets are expected to deliver multidisciplinary applications in drug delivery and medical sciences by e.g. modifying drug solubility/dissolutions or stabilizing the unstable drug (e.g. hormone, protein) in the composite network.

  15. Analysis of advanced vapor source for cadmium telluride solar cell manufacturing

    NASA Astrophysics Data System (ADS)

    Khetani, Tejas Harshadkumar

    A thin film CdS/CdTe solar cell manufacturing line has been developed in the Materials Engineering Laboratory at Colorado State University. The original design incorporated infrared lamps for heating the vapor source. This system has been redesigned to improve the energy efficiency of the system, allow co-sublimation and allow longer run time before the sources have to be replenished. The advanced vapor source incorporates conduction heating with heating elements embedded in graphite. The advanced vapor source was modeled by computational fluid dynamics (CFD). From these models, the required maximum operating temperature of the element was determined to be 720 C for the processing of CdS/CdTe solar cells. Nichrome and Kanthal A1 were primarily selected for this application at temperature of 720 °C in vacuum with oxygen partial pressure. Research on oxidation effects and life due to oxidation as well as creep deformation was done, and Nichrome was found more suitable for this application. A study of the life of the Nichrome heating elements in this application was conducted and the estimate of life is approximately 1900 years for repeated on-off application. This is many orders of magnitude higher than the life of infrared heat lamps. Ceramic cement based on aluminum oxide (Resbond 920) is used for bonding the elements to the graphite. Thermodynamic calculations showed that this cement is inert to the heating element. An earlier design of the advanced source encountered failure of the element. The failed element was studies by scanning electron microscopy and the failure was attributed to loss of adhesion between the graphite and the ceramic element. The design has been modified and the advanced vapor source is currently in operation.

  16. Economizer Based Data Center Liquid Cooling with Advanced Metal Interfaces

    SciTech Connect

    Timothy Chainer

    2012-11-30

    A new chiller-less data center liquid cooling system utilizing the outside air environment has been shown to achieve up to 90% reduction in cooling energy compared to traditional chiller based data center cooling systems. The system removes heat from Volume servers inside a Sealed Rack and transports the heat using a liquid loop to an Outdoor Heat Exchanger which rejects the heat to the outdoor ambient environment. The servers in the rack are cooled using a hybrid cooling system by removing the majority of the heat generated by the processors and memory by direct thermal conduction using coldplates and the heat generated by the remaining components using forced air convection to an air- to- liquid heat exchanger inside the Sealed Rack. The anticipated benefits of such energy-centric configurations are significant energy savings at the data center level. When compared to a traditional 10 MW data center, which typically uses 25% of its total data center energy consumption for cooling this technology could potentially enable a cost savings of up to $800,000-$2,200,000/year (assuming electricity costs of 4 to 11 cents per kilowatt-hour) through the reduction in electrical energy usage.

  17. Center for Technology for Advanced Scientific Componet Software (TASCS)

    SciTech Connect

    Govindaraju, Madhusudhan

    2010-10-31

    Advanced Scientific Computing Research Computer Science FY 2010Report Center for Technology for Advanced Scientific Component Software: Distributed CCA State University of New York, Binghamton, NY, 13902 Summary The overall objective of Binghamton's involvement is to work on enhancements of the CCA environment, motivated by the applications and research initiatives discussed in the proposal. This year we are working on re-focusing our design and development efforts to develop proof-of-concept implementations that have the potential to significantly impact scientific components. We worked on developing parallel implementations for non-hydrostatic code and worked on a model coupling interface for biogeochemical computations coded in MATLAB. We also worked on the design and implementation modules that will be required for the emerging MapReduce model to be effective for scientific applications. Finally, we focused on optimizing the processing of scientific datasets on multi-core processors. Research Details We worked on the following research projects that we are working on applying to CCA-based scientific applications. 1. Non-Hydrostatic Hydrodynamics: Non-static hydrodynamics are significantly more accurate at modeling internal waves that may be important in lake ecosystems. Non-hydrostatic codes, however, are significantly more computationally expensive, often prohibitively so. We have worked with Chin Wu at the University of Wisconsin to parallelize non-hydrostatic code. We have obtained a speed up of about 26 times maximum. Although this is significant progress, we hope to improve the performance further, such that it becomes a practical alternative to hydrostatic codes. 2. Model-coupling for water-based ecosystems: To answer pressing questions about water resources requires that physical models (hydrodynamics) be coupled with biological and chemical models. Most hydrodynamics codes are written in Fortran, however, while most ecologists work in MATLAB. This

  18. Manufacturing Methods and Technology (MANTECH) Program Manufacturing Techniques for a Composite Tail Section for the Advanced Attack Helicopter.

    DTIC Science & Technology

    1981-10-01

    c.l-.kj tnk i r. ib sized to accommodate the local load requircmcnts. I .-,kl, thlckrv. , including laminae and honeycomb core is illuatr1tt1 . t, Vi...occur as a result of manufacturing defects, storage , environmental conditions, in-service conditions, and production techniques. Specific areas of concern...Antenna inopedance, pattern, and cain were ineasured. Ic .- .: te study was to determine if thc eistina 1NI t" 1 \\ ertica --l :JL. r I .:,ilin, Edge

  19. Latest advances in the manufacturing of 3D rechargeable lithium microbatteries

    NASA Astrophysics Data System (ADS)

    Ferrari, Stefania; Loveridge, Melanie; Beattie, Shane D.; Jahn, Marcus; Dashwood, Richard J.; Bhagat, Rohit

    2015-07-01

    Recent advances in micro- and nano-electromechanical systems (MEMS/NEMS) technology have led to a niche industry of diverse small-scale devices that include microsensors, micromachines and drug-delivery systems. For these devices, there is an urgent need to develop Micro Lithium Ion Batteries (MLIBs) with dimensions on the scale 1-10 mm3 enabling on-board power delivery. Unfortunately, power limitations are inherent in planar 2D cells and only the advent of 3D designs and microarchitectures will lead to a real breakthrough in the microbattery technology. During the last few years, many efforts to optimise MLIBs were discussed in literature, both in the planar and 3D configurations. This review highlights the importance of 3D microarchitectured electrodes to fabricate batteries that can be device-integrated with exceptionally high specific power density coupled with exquisite miniaturisation. A wide literature overview is provided and recent advances in manufacturing routes to 3D-MLIBs comprising materials synthesis, device formulation, device testing are herein discussed. The advent of simple, economic and easily scalable fabrication processes such as 3D printing will have a decisive role in the growing field of micropower sources and microdevices.

  20. Improvement of process control using wafer geometry for enhanced manufacturability of advanced semiconductor devices

    NASA Astrophysics Data System (ADS)

    Lee, Honggoo; Lee, Jongsu; Kim, Sang Min; Lee, Changhwan; Han, Sangjun; Kim, Myoungsoo; Kwon, Wontaik; Park, Sung-Ki; Vukkadala, Pradeep; Awasthi, Amartya; Kim, J. H.; Veeraraghavan, Sathish; Choi, DongSub; Huang, Kevin; Dighe, Prasanna; Lee, Cheouljung; Byeon, Jungho; Dey, Soham; Sinha, Jaydeep

    2015-03-01

    Aggressive advancements in semiconductor technology have resulted in integrated chip (IC) manufacturing capability at sub-20nm half-pitch nodes. With this, lithography overlay error budgets are becoming increasingly stringent. The delay in EUV lithography readiness for high volume manufacturing (HVM) and the need for multiple-patterning lithography with 193i technology has further amplified the overlay issue. Thus there exists a need for technologies that can improve overlay errors in HVM. The traditional method for reducing overlay errors predominantly focused on improving lithography scanner printability performance. However, processes outside of the lithography sector known as processinduced overlay errors can contribute significantly to the total overlay at the current requirements. Monitoring and characterizing process-induced overlay has become critical for advanced node patterning. Recently a relatively new technique for overlay control that uses high-resolution wafer geometry measurements has gained significance. In this work we present the implementation of this technique in an IC fabrication environment to monitor wafer geometry changes induced across several points in the process flow, of multiple product layers with critical overlay performance requirement. Several production wafer lots were measured and analyzed on a patterned wafer geometry tool. Changes induced in wafer geometry as a result of wafer processing were related to down-stream overlay error contribution using the analytical in-plane distortion (IPD) calculation model. Through this segmentation, process steps that are major contributors to down-stream overlay were identified. Subsequent process optimization was then isolated to those process steps where maximum benefit might be realized. Root-cause for the within-wafer, wafer-to-wafer, tool-to-tool, and station-to-station variations observed were further investigated using local shape curvature changes - which is directly related to

  1. ADVANCED COMPOSITES TECHNOLOGY CASE STUDY AT NASA LANGLEY RESEARCH CENTER

    EPA Science Inventory

    This report summarizes work conducted at the National Aeronautics and Space Administration's Langley Research Center (NASA-LaRC) in Hampton, VA, under the U.S. Environmental Protection Agency’s (EPA) Waste Reduction Evaluations at Federal Sites (WREAFS) Program. Support for...

  2. Center for Advanced Power and Energy Research (CAPEC)

    DTIC Science & Technology

    2015-01-01

    University structured through a cooperative research agreement. Our organizational focuses include: 1. Modeling of plasma physics 2. Modeling fuel cells 3...Testing new innovation and ideas for advanced fuel cells 4. Development of energy related issue for micro air vehicles (MAVs). 15. SUBJECT TERMS plasma ...1 2 Plasma Modeling

  3. Advanced Composite Structures At NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Eldred, Lloyd B.

    2015-01-01

    Dr. Eldred's presentation will discuss several NASA efforts to improve and expand the use of composite structures within aerospace vehicles. Topics will include an overview of NASA's Advanced Composites Project (ACP), Space Launch System (SLS) applications, and Langley's ISAAC robotic composites research tool.

  4. Advanced Measurement Technology at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Antcliff, Richard R.

    1998-01-01

    Instrumentation systems have always been essential components of world class wind tunnels and laboratories. Langley continues to be on the forefront of the development of advanced systems for aerospace applications. This paper will describe recent advances in selected measurement systems which have had significant impact on aerospace testing. To fully understand the aerodynamics and aerothermodynamics influencing aerospace vehicles, highly accurate and repeatable measurements need to be made of critical phenomena. However, to maintain leadership in a highly competitive world market, productivity enhancement and the development of new capabilities must also be addressed aggressively. The accomplishment of these sometimes conflicting requirements has been the challenge of advanced measurement developers. However, several new technologies have recently matured to the point where they have enabled the achievement of these goals. One of the critical areas where advanced measurement systems are required is flow field velocity measurements. These measurements are required to correctly characterize the flowfield under study, to quantify the aerodynamic performance of test articles and to assess the effect of aerodynamic vehicles on their environment. Advanced measurement systems are also making great strides in obtaining planar measurements of other important thermodynamic quantities, including species concentration, temperature, pressure and the speed of sound. Langley has been on the forefront of applying these technologies to practical wind tunnel environments. New capabilities in Projection Moire Interferometry and Acoustics Array Measurement systems have extended our capabilities into the model deformation, vibration and noise measurement arenas. An overview of the status of these techniques and recent applications in practical environments will be presented in this paper.

  5. Advanced Life Support Project: Crop Experiments at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Sager, John C.; Stutte, Gary W.; Wheeler, Raymond M.; Yorio, Neil

    2004-01-01

    Crop production systems provide bioregenerative technologies to complement human crew life support requirements on long duration space missions. Kennedy Space Center has lead NASA's research on crop production systems that produce high value fresh foods, provide atmospheric regeneration, and perform water processing. As the emphasis on early missions to Mars has developed, our research focused on modular, scalable systems for transit missions, which can be developed into larger autonomous, bioregenerative systems for subsequent surface missions. Components of these scalable systems will include development of efficient light generating or collecting technologies, low mass plant growth chambers, and capability to operate in the high energy background radiation and reduced atmospheric pressures of space. These systems will be integrated with air, water, and thermal subsystems in an operational system. Extensive crop testing has been done for both staple and salad crops, but limited data is available on specific cultivar selection and breadboard testing to meet nominal Mars mission profiles of a 500-600 day surface mission. The recent research emphasis at Kennedy Space Center has shifted from staple crops, such as wheat, soybean and rice, toward short cycle salad crops such as lettuce, onion, radish, tomato, pepper, and strawberry. This paper will review the results of crop experiments to support the Exploration Initiative and the ongoing development of supporting technologies, and give an overview of capabilities of the newly opened Space Life Science (SLS) Lab at Kennedy Space Center. The 9662 square m (104,000 square ft) SLS Lab was built by the State of Florida and supports all NASA research that had been performed in Hanger-L. In addition to NASA research, the SLS Lab houses the Florida Space Research Institute (FSRI), responsible for co-managing the facility, and the University of Florida (UF) has established the Space Agriculture and Biotechnology Research and

  6. 78 FR 26377 - National Center for Advancing Translational Sciences; Notice of Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ..., Bethesda, MD 20892. Contact Person: Danilo A. Tagle, Ph.D., Executive Secretary, National Center for....Tagle@nih.gov . This notice is being published less than 15 days prior to the meeting due to scheduling...: Danilo A. Tagle, Ph.D., Executive Secretary, National Center for Advancing Translational, Sciences,...

  7. NASA University Research Centers Technical Advances in Education, Aeronautics, Space, Autonomy, Earth and Environment

    NASA Technical Reports Server (NTRS)

    Jamshidi, M. (Editor); Lumia, R. (Editor); Tunstel, E., Jr. (Editor); White, B. (Editor); Malone, J. (Editor); Sakimoto, P. (Editor)

    1997-01-01

    This first volume of the Autonomous Control Engineering (ACE) Center Press Series on NASA University Research Center's (URC's) Advanced Technologies on Space Exploration and National Service constitute a report on the research papers and presentations delivered by NASA Installations and industry and Report of the NASA's fourteen URC's held at the First National Conference in Albuquerque, New Mexico from February 16-19, 1997.

  8. ROBOTICALLY ENHANCED ADVANCED MANUFACTURING CONCEPTS TO OPTIMIZE ENERGY, PRODUCTIVITY, AND ENVIRONMENTAL PERFORMANCE

    SciTech Connect

    Larry L. Keller; Joseph M. Pack; Robert V. Kolarik II

    2007-11-05

    In the first phase of the REML project, major assets were acquired for a manufacturing line for follow-on installation, capability studies and optimization. That activity has been documented in the DE-FC36-99ID13819 final report. In this the second phase of the REML project, most of the major assets have been installed in a manufacturing line arrangement featuring a green cell, a thermal treatment cell and a finishing cell. Most of the secondary and support assets have been acquired and installed. Assets have been integrated with a commercial, machine-tending gantry robot in the thermal treatment cell and with a low-mass, high-speed gantry robot in the finish cell. Capabilities for masterless gauging of product’s dimensional and form characteristics were advanced. Trial production runs across the entire REML line have been undertaken. Discrete event simulation modeling has aided in line balancing and reduction of flow time. Energy, productivity and cost, and environmental comparisons to baselines have been made. Energy The REML line in its current state of development has been measured to be about 22% (338,000 kVA-hrs) less energy intensive than the baseline conventional low volume line assuming equivalent annual production volume of approximately 51,000 races. The reduction in energy consumption is largely attributable to the energy reduction in the REML thermal treatment cell where the heating devices are energized on demand and are appropriately sized to the heating load of a near single piece flow line. If additional steps such as power factor correction and use of high-efficiency motors were implemented to further reduce energy consumption, it is estimated, but not yet demonstrated, that the REML line would be about 30% less energy intensive than the baseline conventional low volume line assuming equivalent annual production volume. Productivity The capital cost of an REML line would be roughly equivalent to the capital cost of a new conventional line. The

  9. Development of advanced manufacturing technologies for low cost hydrogen storage vessels

    SciTech Connect

    Leavitt, Mark; Lam, Patrick

    2014-12-29

    The U.S. Department of Energy (DOE) defined a need for low-cost gaseous hydrogen storage vessels at 700 bar to support cost goals aimed at 500,000 units per year. Existing filament winding processes produce a pressure vessel that is structurally inefficient, requiring more carbon fiber for manufacturing reasons, than would otherwise be necessary. Carbon fiber is the greatest cost driver in building a hydrogen pressure vessel. The objective of this project is to develop new methods for manufacturing Type IV pressure vessels for hydrogen storage with the purpose of lowering the overall product cost through an innovative hybrid process of optimizing composite usage by combining traditional filament winding (FW) and advanced fiber placement (AFP) techniques. A numbers of vessels were manufactured in this project. The latest vessel design passed all the critical tests on the hybrid design per European Commission (EC) 79-2009 standard except the extreme temperature cycle test. The tests passed include burst test, cycle test, accelerated stress rupture test and drop test. It was discovered the location where AFP and FW overlap for load transfer could be weakened during hydraulic cycling at 85°C. To design a vessel that passed these tests, the in-house modeling software was updated to add capability to start and stop fiber layers to simulate the AFP process. The original in-house software was developed for filament winding only. Alternative fiber was also investigated in this project, but the added mass impacted the vessel cost negatively due to the lower performance from the alternative fiber. Overall the project was a success to show the hybrid design is a viable solution to reduce fiber usage, thus driving down the cost of fuel storage vessels. Based on DOE’s baseline vessel size of 147.3L and 91kg, the 129L vessel (scaled to DOE baseline) in this project shows a 32% composite savings and 20% cost savings when comparing Vessel 15 hybrid design and the Quantum

  10. Advances in compact manufacturing for shape and performance controllability of large-scale components-a review

    NASA Astrophysics Data System (ADS)

    Qin, Fangcheng; Li, Yongtang; Qi, Huiping; Ju, Li

    2017-01-01

    Research on compact manufacturing technology for shape and performance controllability of metallic components can realize the simplification and high-reliability of manufacturing process on the premise of satisfying the requirement of macro/micro-structure. It is not only the key paths in improving performance, saving material and energy, and green manufacturing of components used in major equipments, but also the challenging subjects in frontiers of advanced plastic forming. To provide a novel horizon for the manufacturing in the critical components is significant. Focused on the high-performance large-scale components such as bearing rings, flanges, railway wheels, thick-walled pipes, etc, the conventional processes and their developing situations are summarized. The existing problems including multi-pass heating, wasting material and energy, high cost and high-emission are discussed, and the present study unable to meet the manufacturing in high-quality components is also pointed out. Thus, the new techniques related to casting-rolling compound precise forming of rings, compact manufacturing for duplex-metal composite rings, compact manufacturing for railway wheels, and casting-extruding continuous forming of thick-walled pipes are introduced in detail, respectively. The corresponding research contents, such as casting ring blank, hot ring rolling, near solid-state pressure forming, hot extruding, are elaborated. Some findings in through-thickness microstructure evolution and mechanical properties are also presented. The components produced by the new techniques are mainly characterized by fine and homogeneous grains. Moreover, the possible directions for further development of those techniques are suggested. Finally, the key scientific problems are first proposed. All of these results and conclusions have reference value and guiding significance for the integrated control of shape and performance in advanced compact manufacturing.

  11. Advanced interactive displays for deployable command and control centers

    NASA Astrophysics Data System (ADS)

    Jedrysik, Peter A.; Parada, Francisco E.; Stedman, Terrance A.; Zhang, Jingyuan

    2003-09-01

    Command and control in today's battlefield environment requires efficient and effective control of massive amounts of constantly changing information from a variety of databases and real-time sensors. Using advanced information technology for presentation and interactive control enables more extensive data fusion and correlation to present an accurate picture of the battlespace to commanders and their staffs. The Interactive DataWall being developed by the Advanced Displays and Intelligent Interfaces (ADII) technology team of the Air Force Research Laboratory's Information Directorate (AFRL/IF) is a strong contender for solving the information management problems facing the 21st century military commander. It provides an ultra high-resolution large screen display with multi-modal, wireless interaction. Commercial off-the-shelf (COTS) technology has been combined with specialized hardware and software developed in-house to provide a unique capability for multimedia data display and control. The technology once isolated to a laboratory environment has been packaged into deployable systems that have been successfully transitioned to support the warfighter in the field.

  12. 77 FR 37653 - Manufacturing Extension Partnership (MEP) Centers for Arizona, Maryland and Rhode Island...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... Technology (NIST), United States Department of Commerce (DoC). ACTION: Notice. SUMMARY: NIST invites... primarily small- and medium-sized manufacturers in the United States. Specifically, NIST seeks proposals for... at Tel: (301) 975-5105; Email: diane.henderson@nist.gov ; Fax: (301) 963-6556. Grants...

  13. Final Report - Advanced MEA's for Enhanced Operating Conditions, Amenable to High Volume Manufacture

    SciTech Connect

    Debe, Mark K.

    2007-09-30

    This report summarizes the work completed under a 3M/DOE contract directed at advancing the key fuel cell (FC) components most critical for overcoming the polymer electrolyte membrane fuel cell (PEMFC) performance, durability & cost barriers. This contract focused on the development of advanced ion exchange membranes & electrocatalysts for PEMFCs that will enable operation under ever more demanding automotive operating conditions & the use high volume compatible processes for their manufacture. Higher performing & more durable electrocatalysts must be developed for PEMFCs to meet the power density & lifetime hours required for FC vehicles. At the same time the amount of expensive Pt catalyst must be reduced to lower the MEA costs. While these two properties are met, the catalyst must be made resistant to multiple degradation mechanisms to reach necessary operating lifetimes. In this report, we present the work focused on the development of a completely new approach to PEMFC electrocatalyts, called nanostructured thin film (NSTF) catalysts. The carbon black supports are eliminated with this new approach which eliminates the carbon corrosion issue. The thin film nature of the catalyst significantly improves its robustness against dissolution & grain growth, preserving the surface area. Also, the activity of the NSTF for oxygen reduction is improved by over 500% compared to dispersed Pt catalyts. Finally, the process for fabricating the NSTF catalysts is consistent with high volume roll-good manufacturing & extremely flexible towards the introduction of new catalyst compositions & structures. This report documents the work done to develop new multi-element NSTF catalysts with properties that exceed pure Pt, that are optimized for use with the membranes discussed below, & advance the state-of-the-art towards meeting the DOE 2010 targets for PEMFC electrocatalysts. The work completed advances the understanding of the NSTF catalyst technology, identifies new NSTF

  14. Report to the President on Ensuring American Leadership in Advanced Manufacturing

    ERIC Educational Resources Information Center

    Anderson, Alan

    2011-01-01

    The United States has long thrived as a result of its ability to manufacture goods and sell them to global markets. Manufacturing activity has supported its economic growth, leading the Nation's exports and employing millions of Americans. The manufacturing sector has also driven knowledge production and innovation in the United States, by…

  15. Report on Advanced Life Support Activities at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Wheeler, Raymond M.

    2004-01-01

    Plant studies at Kennedy Space Center last year focused on selecting cultivars of lettuce, tomato, and pepper for further testing as crops for near-term space flight applications. Other testing continued with lettuce, onion, and radish plants grown at different combinations of light (PPF), temperature, and CO2 concentration. In addition, comparisons of mixed versus mono culture approaches for vegetable production were studied. Water processing testing focused on the development and testing of a rotating membrane bioreactor to increase oxygen diffusion levels for reducing total organic carbon levels and promoting nitrification. Other testing continued to study composting testing for food wastes (NRA grant) and the use of supplemental green light with red/blue LED lighting systems for plant production (NRC fellowship).

  16. Software development for the evaluation of the ergonomic compatibility on the selection of advanced manufacturing technology.

    PubMed

    Maldonado-Macías, A; Reyes, R; Guillen, L; García, J

    2012-01-01

    Advanced Manufacturing Technology (AMT) is one of the most relevant resources that companies have to achieve competitiveness and best performance. The selection of AMT is a complex problem which involves significant amount of information and uncertainty when multiple aspects must be taken into consideration. Actual models for the selection of AMT are found scarce of the Human Factors and Ergonomics perspective which can lead to a more complete and reliable decision. This paper presents the development of software that enhances the application of an Ergonomic Compatibility Evaluation Model that supports decision making processes taking into consideration ergonomic attributes of designs. Ergonomic Compatibility is a construct used in this model and it is mainly based in the concept of human-artifact compatibility on human compatible systems. Also, an Axiomatic Design approach by the use of the Information Axiom was evolved under a fuzzy environment to obtain the Ergonomic Incompatibility Content. The extension of this axiom for the evaluation of ergonomic compatibility requirements was the theoretical framework of this research. An incremental methodology of four stages was used to design and develop the software that enables to compare AMT alternatives by the evaluation of Ergonomic Compatibility Attributes.

  17. Using advanced manufacturing to produce unmanned aerial vehicles: a feasibility study

    NASA Astrophysics Data System (ADS)

    Easter, Steven; Turman, Jonathan; Sheffler, David; Balazs, Michael; Rotner, Jonathan

    2013-05-01

    This paper reports on a feasibility study to explore the impact of advanced manufacturing on the production and maintenance of a 3D printed, unmanned aerial vehicle (UAV) in theatre. Specifically, this report focuses on fused deposition modeling (FDM), the selective deposition of a molten thermoplastic. FDM is already a forward deployed technology, primarily used for printing custom tools and replacement parts. The authors ask if it is feasible to expand the printers' capacity to produce aerial platforms; the reduction in logistics and labor could significantly decrease costs per unit and enable far more platform customization and specialized deployment scenarios than are available in existing aircraft. The University of Virginia and The MITRE Corporation designed and built a prototype, 3D printed UAV for use as an aerial sensor platform. This report • Discusses the printed aerial platform, summarizes the design process, and compares printing methods • Describes the benefits and limitations to selecting FDM printers as the technology both for deployment as well as UAV design • Concludes with the current state and future expectations for FDM printing technologies relevant to UAV production. Our findings suggest that although 3D printing is not yet entirely field-ready, many of its advantages can already be realized.

  18. Technology-design-manufacturing co-optimization for advanced mobile SoCs

    NASA Astrophysics Data System (ADS)

    Yang, Da; Gan, Chock; Chidambaram, P. R.; Nallapadi, Giri; Zhu, John; Song, S. C.; Xu, Jeff; Yeap, Geoffrey

    2014-03-01

    How to maintain the Moore's Law scaling beyond the 193 immersion resolution limit is the key question semiconductor industry needs to answer in the near future. Process complexity will undoubtfully increase for 14nm node and beyond, which brings both challenges and opportunities for technology development. A vertically integrated design-technologymanufacturing co-optimization flow is desired to better address the complicated issues new process changes bring. In recent years smart mobile wireless devices have been the fastest growing consumer electronics market. Advanced mobile devices such as smartphones are complex systems with the overriding objective of providing the best userexperience value by harnessing all the technology innovations. Most critical system drivers are better system performance/power efficiency, cost effectiveness, and smaller form factors, which, in turns, drive the need of system design and solution with More-than-Moore innovations. Mobile system-on-chips (SoCs) has become the leading driver for semiconductor technology definition and manufacturing. Here we highlight how the co-optimization strategy influenced architecture, device/circuit, process technology and package, in the face of growing process cost/complexity and variability as well as design rule restrictions.

  19. Advances in the Manufacture of Omega-scale Double-shell Targets

    NASA Astrophysics Data System (ADS)

    Bono, M.

    2005-10-01

    The double-shell ignition target design consists of a low-Z outer shell that absorbs hohlraum-generated x-rays, implodes, and collides with a high-Z inner shell containing DT fuel. Efforts are continuing to field scaled ignition-like double shells on the Omega laser facility over a range of inner-shell Z. Previous ignition-like double-shell implosions on Omega used a low-Z CH inner shell [1]. The current target contains a higher-Z glass inner shell of diameter 216 microns, which is supported by SiO2 aerogel inside a Br-doped CH ablator shell of diameter 550 microns. Fielding double-shell targets has historically been limited by the ability to successfully fabricate them, but several technological advances have recently been made in the manufacturing process. The inner capsule will be cast in SiO2 aerogel of density 50 mg/cc, whose outer contour will be machined concentric to the inner capsule. This piece will then be assembled between two hemispherical ablator shells that mate at a step-joint with an adhesive-filled gap of thickness 100 nm. Three-dimensional tomographs made of each target using an x-ray micro-tomography system will allow precise characterization of the targets. [1] P. Amendt et al., Phys. Rev. Lett. 94, 065004 (2005).

  20. Proposed center for advanced industrial processes. Washington State University, College of Engineering and Architecture

    SciTech Connect

    1995-03-01

    The DOE proposes to authorize Washington State University (WSU) to proceed with the detailed design, construction, and equipping of the proposed Center for Advanced Industrial Processes (CAIP). The proposed project would involve construction of a three story building containing laboratories, classrooms, seminar rooms, and graduate student and administrative office space. Existing buildings would be demolished. The proposed facility would house research in thermal/fluid sciences, bioengineering, manufacturing processes, and materials processing. Under the {open_quotes}no-action{close_quotes} DOE would not authorize WSU to proceed with construction under the grant. WSU would then need to consider alternatives for proceeding without DOE funds. Such alternatives (including delaying or scaling back the project), would result in a postponement or slight reduction in the minor adverse environmental, safety and health Impacts of the project evaluated in this assessment. More importantly, these alternatives would affect the important environmental, safety, health, and programmatic benefits of the projects. The surrounding area is fully urbanized and the campus is intensely developed around the proposed site. The buildings scheduled for demolition do not meet State energy codes, are not air conditioned, and lack handicapped access. Sensitive resources (historical/archeological, protected species/critical habitats, wetlands/floodplains, national forests/parks/trails, prime farmland and special sources of water) would not be affected as they do not occur on or near the proposed site. Cumulative impacts would be small. The proposed action is not related to other actions being considered under other NEPA reviews. There is no conflict between the proposed action and any applicable Federal, State, regional or local land use plans and policies.

  1. Advances in Materials Research: An Internship at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Barrios, Elizabeth A.; Roberson, Luke B.

    2011-01-01

    My time at Kennedy Space Center. was spent immersing myself in research performed in the Materials Science Division of the Engineering Directorate. My Chemical Engineering background provided me the ability to assist in many different projects ranging from tensile testing of composite materials to making tape via an extrusion process. However, I spent the majority of my time on the following three projects: (1) testing three different materials to determine antimicrobial properties; (2) fabricating and analyzing hydrogen sensing tapes that were placed at the launch pad for STS-133 launch; and (3) researching molten regolith electrolysis at KSC to prepare me for my summer internship at MSFC on a closely related topic. This paper aims to explain, in detail, what I have learned about these three main projects. It will explain why this research is happening and what we are currently doing to resolve the issues. This paper will also explain how the hard work and experiences that I have gained as an intern have provided me with the next big step towards my career at NASA.

  2. Development of Advanced Hydrocarbon Fuels at Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Bai, S. D.; Dumbacher, P.; Cole, J. W.

    2002-01-01

    This was a small-scale, hot-fire test series to make initial measurements of performance differences of five new liquid fuels relative to rocket propellant-1 (RP-1). The program was part of a high-energy-density materials development at Marshall Space Flight Center (MSFC), and the fuels tested were quadricyclane, 1-7 octodiyne, AFRL-1, biclopropylidene, and competitive impulse noncarcinogenic hypergol (CINCH) (di-methyl-aminoethyl-azide). All tests were conducted at MSFC. The first four fuels were provided by the U.S. Air Force Research Laboratory (AFRL), Edwards Air Force Base, CA. The U.S. Army, Redstone Arsenal, Huntsville, AL, provided the CINCH. The data recorded in all hot-fire tests were used to calculate specific impulse and characteristic exhaust velocity for each fuel, then compared to RP-1 at the same conditions. This was not an exhaustive study, comparing each fuel to RP-1 at an array of mixture ratios, nor did it include important fuel parameters, such as fuel handling or long-term storage. The test hardware was designed for liquid oxygen (lox)/RP-1, then modified for gaseous oxygen/RP-1 to avoid two-phase lox at very small flow rates. All fuels were tested using the same thruster/injector combination designed for RP-1. The results of this test will be used to determine which fuels will be tested in future test programs.

  3. The ADVANCE network: accelerating data value across a national community health center network

    PubMed Central

    DeVoe, Jennifer E; Gold, Rachel; Cottrell, Erika; Bauer, Vance; Brickman, Andrew; Puro, Jon; Nelson, Christine; Mayer, Kenneth H; Sears, Abigail; Burdick, Tim; Merrell, Jonathan; Matthews, Paul; Fields, Scott

    2014-01-01

    The ADVANCE (Accelerating Data Value Across a National Community Health Center Network) clinical data research network (CDRN) is led by the OCHIN Community Health Information Network in partnership with Health Choice Network and Fenway Health. The ADVANCE CDRN will ‘horizontally’ integrate outpatient electronic health record data for over one million federally qualified health center patients, and ‘vertically’ integrate hospital, health plan, and community data for these patients, often under-represented in research studies. Patient investigators, community investigators, and academic investigators with diverse expertise will work together to meet project goals related to data integration, patient engagement and recruitment, and the development of streamlined regulatory policies. By enhancing the data and research infrastructure of participating organizations, the ADVANCE CDRN will serve as a ‘community laboratory’ for including disadvantaged and vulnerable patients in patient-centered outcomes research that is aligned with the priorities of patients, clinics, and communities in our network. PMID:24821740

  4. Advanced treatment of wet-spun acrylic fiber manufacturing wastewater using three-dimensional electrochemical oxidation.

    PubMed

    Zheng, Tianlong; Wang, Qunhui; Shi, Zhining; Fang, Yue; Shi, Shanshan; Wang, Juan; Wu, Chuanfu

    2016-12-01

    A three-dimensional electrochemical oxidation (3D-EC) reactor with introduction of activated carbon (AC) as particle micro-electrodes was applied for the advanced treatment of secondary wastewater effluent of a wet-spun acrylic fiber manufacturing plant. Under the optimized conditions (current density of 500A/m(2), circulation rate of 5mL/min, AC dosage of 50g, and chloride concentration of 1.0g/L), the average removal efficiencies of chemical oxygen demand (CODcr), NH3-N, total organic carbon (TOC), and ultraviolet absorption at 254nm (UV254) of the 3D-EC reactor were 64.5%, 60.8%, 46.4%, and 64.8%, respectively; while the corresponding effluent concentrations of CODcr, NH3-N, TOC, and UV254 were 76.6, 20.1, and 42.5mg/L, and 0.08Abs/cm, respectively. The effluent concentration of CODcr was less than 100mg/L, which showed that the treated wastewater satisfied the demand of the integrated wastewater discharge standard (GB 8978-1996). The 3D-EC process remarkably improved the treatment efficiencies with synergistic effects for CODcr, NH3-N, TOC, and UV254 during the stable stage of 44.5%, 38.8%, 27.2%, and 10.9%, respectively, as compared with the sum of the efficiencies of a two-dimensional electrochemical oxidation (2D-EC) reactor and an AC adsorption process, which was ascribed to the numerous micro-electrodes of AC in the 3D-EC reactor. Gas chromatography mass spectrometry (GC-MS) analysis revealed that electrochemical treatment did not generate more toxic organics, and it was proved that the increase in acute biotoxicity was caused primarily by the production of free chlorine.

  5. An Assessment of Critical Dimension Small Angle X-ray Scattering Metrology for Advanced Semiconductor Manufacturing

    SciTech Connect

    Settens, Charles M.

    2015-01-01

    Simultaneous migration of planar transistors to FinFET architectures, the introduction of a plurality of materials to ensure suitable electrical characteristics, and the establishment of reliable multiple patterning lithography schemes to pattern sub-10 nm feature sizes imposes formidable challenges to current in-line dimensional metrologies. Because the shape of a FinFET channel cross-section immediately influences the electrical characteristics, the evaluation of 3D device structures requires measurement of parameters beyond traditional critical dimension (CD), including their sidewall angles, top corner rounding and footing, roughness, recesses and undercuts at single nanometer dimensions; thus, metrologies require sub-nm and approaching atomic level measurement uncertainty. Synchrotron critical dimension small angle X-ray scattering (CD-SAXS) has unique capabilities to non-destructively monitor the cross-section shape of surface structures with single nanometer uncertainty and can perform overlay metrology to sub-nm uncertainty. In this dissertation, we perform a systematic experimental investigation using CD-SAXS metrology on a hierarchy of semiconductor 3D device architectures including, high-aspect-ratio contact holes, H2 annealed Si fins, and a series of grating type samples at multiple points along a FinFET fabrication process increasing in structural intricacy and ending with fully fabricated FinFET. Comparative studies between CD-SAXS metrology and other relevant semiconductor dimensional metrologies, particularly CDSEM, CD-AFM and TEM are used to determine physical limits of CD-SAXS approach for advanced semiconductor samples. CD-SAXS experimental tradeoffs, advice for model-dependent analysis and thoughts on the compatibility with a semiconductor manufacturing environment are discussed.

  6. IMPROVEMENT OF WEAR COMPONENT'S PERFORMANCE BY UTILIZING ADVANCED MATERIALS AND NEW MANUFACTURING TECHNOLOGIES: CASTCON PROCESS FOR MINING APPLICATIONS

    SciTech Connect

    Xiaodi Huang; Richard Gertsch

    2005-02-04

    Michigan Technological University, together with The Robbins Group, Advanced Ceramic Research, Advanced Ceramic Manufacturing, and Superior Rock Bits, evaluated a new process and a new material for producing drill bit inserts and disc cutters for the mining industry. Difficulties in the material preparation stage slowed the research initially. Prototype testing of the drill bit inserts showed that the new inserts did not perform up to the current state of the art. Due to difficulties in the prototype production of the disc cutters, the disc cutter was manufactured but not tested. Although much promising information was obtained as a result of this project, the objective of developing an effective means for producing rock drill bits and rock disc cutters that last longer, increase energy efficiency and penetration rate, and lower overall production cost was not met.

  7. Microgravity polymer and crystal growth at the Advanced Materials Center for the Commercial Development of Space

    NASA Technical Reports Server (NTRS)

    Mccauley, Lisa A.

    1990-01-01

    The microgravity research programs currently conducted by the Advanced Materials Center for the Commercial Development of Space (CCDS) are briefly reviewed. Polymer processing in space, which constitutes the most active microgravity program at the Advanced Materials CCDS, is conducted in three areas: membrane processing, multiphase composite behavior, and plasma polymerization. Current work in microgravity crystal growth is discussed with particular reference to the development of the Zeolite Crystal Growth facility.

  8. V1.6 Development of Advanced Manufacturing Technologies for Low Cost Hydrogen Storage Vessels

    SciTech Connect

    Leavitt, Mark; Lam, Patrick; Nelson, Karl M.; johnson, Brice A.; Johnson, Kenneth I.; Alvine, Kyle J.; Ruiz, Antonio; Adams, Jesse

    2012-10-01

    The goal of this project is to develop an innovative manufacturing process for Type IV high-pressure hydrogen storage vessels, with the intent to significantly lower manufacturing costs. Part of the development is to integrate the features of high precision AFP and commercial FW. Evaluation of an alternative fiber to replace a portion of the baseline fiber will help to reduce costs further.

  9. The next frontier: stem cells and the Center for the Advancement of Science in Space.

    PubMed

    Ratliff, Duane

    2013-12-01

    The Center for the Advancement of Science in Space (CASIS) manages the International Space Station U.S. National Laboratory, supporting space-based research that seeks to improve life on Earth. The National Laboratory is now open for use by the broad scientific community--and CASIS is the gateway to this powerful in-orbit research platform.

  10. Community College Advanced Technology Centers: Meeting America's Need for Integrated, Comprehensive Economic Development.

    ERIC Educational Resources Information Center

    Hinckley, Richard; And Others

    By entering into partnerships with business and industry, community colleges are able to offset the high cost of remaining current with training techniques, job market skill requirements, and state-of-the-art hardware. The construction of advanced technology centers (ATCs) located on community college campuses is one key element supporting these…

  11. 78 FR 21131 - National Center for Advancing Translational Sciences; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ... Democracy Plaza, 6701 Democracy Boulevard, Bethesda, MD 20892, (Telephone Conference Call). Contact Person... Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 6701 Democracy Blvd., Democracy 1, Room 1084, Bethesda, MD 20892-4874, 301-435-0829, mv10f@nih.gov . Name of Committee:...

  12. Advanced composite rudders for DC-10 aircraft: Design, manufacturing, and ground tests

    NASA Technical Reports Server (NTRS)

    Lehman, G. M.; Purdy, D. M.; Cominsky, A.; Hawley, A. V.; Amason, M. P.; Kung, J. T.; Palmer, R. J.; Purves, N. B.; Marra, P. J.; Hancock, G. R.

    1976-01-01

    Design synthesis, tooling and process development, manufacturing, and ground testing of a graphite epoxy rudder for the DC-10 commercial transport are discussed. The composite structure was fabricated using a unique processing method in which the thermal expansion characteristics of rubber tooling mandrels were used to generate curing pressures during an oven cure cycle. The ground test program resulted in certification of the rudder for passenger-carrying flights. Results of the structural and environmental tests are interpreted and detailed development of the rubber tooling and manufacturing process is described. Processing, tooling, and manufacturing problems encountered during fabrication of four development rudders and ten flight-service rudders are discussed and the results of corrective actions are described. Non-recurring and recurring manufacturing labor man-hours are tabulated at the detailed operation level. A weight reduction of 13.58 kg (33 percent) was attained in the composite rudder.

  13. NDE of additively manufactured components with embedded defects (reference standards) using conventional and advanced ultrasonic methods

    NASA Astrophysics Data System (ADS)

    Koester, L.; Roberts, R. A.; Barnard, D. J.; Chakrapani, S.; Singh, S.; Hogan, R.; Bond, L. J.

    2017-02-01

    Additive manufacturing provides a unique opportunity to embed defects of known size and shape to produce reference samples for inspection and quality control purposes. This paper reports defect detectability studies with cylindrical additively manufactured cobalt-chromium alloy specimens which contain defects of known sizes and distributions. The specimens were characterized using immersion, synthetic aperture focusing (SAFT), phased array, and nonlinear ultrasonic techniques. Results include detectability, signal to noise ratios, and comparison of results between the methods and what is believed to be the first determination of a non-linearity (beta) parameter for an additively manufactured material. The results indicate that additive manufacturing provides a valuable method to produce reference samples, though additional work is required to validate the shape and morphology of the defects specified.

  14. Field Evaluation of Advances in Energy-Efficiency Practices for Manufactured Homes

    SciTech Connect

    E. Levy; Dentz, J.; Ansanelli, E.; Barker, G.; Rath, P.; Dadia, D.

    2016-03-01

    Through field-testing and analysis, this project evaluated whole-building approaches and estimated the relative contributions of select technologies toward reducing energy use related to space conditioning in new manufactured homes. Three lab houses of varying designs were built and tested side-by-side under controlled conditions in Russellville, Alabama. The tests provided a valuable indicator of how changes in the construction of manufactured homes can contribute to significant reductions in energy use.

  15. Mary S. Easton Center of Alzheimer's Disease Research at UCLA: advancing the therapeutic imperative.

    PubMed

    Cummings, Jeffrey L; Ringman, John; Metz, Karen

    2010-01-01

    The Mary S. Easton Center for Alzheimer's Disease Research (UCLA-Easton Alzheimer's Center) is committed to the "therapeutic imperative" and is devoted to finding new treatments for Alzheimer's disease (AD) and to developing technologies (biomarkers) to advance that goal. The UCLA-Easton Alzheimer's Center has a continuum of research and research-related activities including basic/foundational studies of peptide interactions; translational studies in transgenic animals and other animal models of AD; clinical research to define the phenotype of AD, characterize familial AD, develop biomarkers, and advance clinical trials; health services and outcomes research; and active education, dissemination, and recruitment activities. The UCLAEaston Alzheimer's Center is supported by the National Institutes on Aging, the State of California, and generous donors who share our commitment to developing new therapies for AD. The naming donor (Jim Easton) provided substantial funds to endow the center and to support projects in AD drug discovery and biomarker development. The Sidell-Kagan Foundation supports the Katherine and Benjamin Kagan Alzheimer's Treatment Development Program, and the Deane F. Johnson Alzheimer's Research Foundation supports the Deane F. Johnson Center for Neurotherapeutics at UCLA. The John Douglas French Alzheimer's Research Foundation provides grants to junior investigators in critical periods of their academic development. The UCLA-Easton Alzheimer's Center partners with community organizations including the Alzheimer's Association California Southland Chapter and the Leeza Gibbons memory Foundation. Collaboration with pharmaceutical companies, biotechnology companies, and device companies is critical to developing new therapeutics for AD and these collaborations are embraced in the mission of the UCLA-Easton Alzheimer's Center. The Center supports excellent senior 3 investigators and serves as an incubator for new scientists, agents, models, technologies

  16. United States of America Department of Health and Human Services support for advancing influenza vaccine manufacturing in the developing world.

    PubMed

    Perdue, Michael L; Bright, Rick A

    2011-07-01

    Since 2005, the Government of the United States of America has provided more than US$ 50 million to advance influenza vaccine development in low-resourced countries. This programme has provided a unique opportunity for the US Government to develop a comprehensive view of, and to understand better the challenges and future needs for influenza vaccines in the developing world. The funding for this programme has been primarily through a cooperative agreement with the World Health Organization (WHO) to support directly its capacity-building grants to government-owned or -supported vaccine manufacturers in developing countries. A second cooperative agreement with the Program for Appropriate Technologies in Health (PATH) was initiated to accelerate the completion of a current Good Manufacturing Practice cGMP production facility, along with supporting facilities to obtain a reliable source of eggs, and to conduct clinical trials of influenza vaccine manufactured in Vietnam. This mechanism of utilizing cooperative agreements to support capacity-building for vaccine development in low-resourced settings has been novel and unique and has yielded fruitful returns on minimal investment. The information derived from this programme helps to clarify not only the development challenges for influenza vaccines and how the United States may assist in meeting those challenges, but also other vaccine development issues common to manufacturers in developing countries. While building the initial capacity to produce influenza vaccines can be a straightforward exercise, the sustainability of the enterprise and expansion of subsequent markets will be the key to future usefulness. There is hope for expansion of the global influenza vaccine market. Ongoing burden of disease studies are elucidating the impact of influenza infections, particularly in children, and more countries will take note and respond accordingly, since respiratory diseases are now the number one killer of children under

  17. Roll-to-Roll Advanced Materials Manufacturing DOE Lab Consortium - FY16 Annual Report

    SciTech Connect

    Daniel, Claus; Wood, III, David L.; Krumdick, Gregory; Ulsh, Michael; Srinivasan, Venkat

    2016-12-01

    A DOE laboratory consortium comprised of ORNL, ANL, NREL and LBNL, coordinating with Kodak’s Eastman Business Park (Kodak) and other selected industry partners, was formed to address enhancing battery electrode performance and R2R manufacturing challenges. The objective of the FY 2016 seed project was to develop a materials genome synthesis process amenable to R2R manufacturing and to provide modeling, simulation, processing, and manufacturing techniques that demonstrate the feasibility of process controls and scale-up potential for improved battery electrodes. The research efforts were to predict and measure changes and results in electrode morphology and performance based on process condition changes; to evaluate mixed, active, particle size deposition and drying for novel electrode materials; and to model various process condition changes and the resulting morphology and electrode performance.

  18. Effects of copper content on the shell characteristics of hollow steel spheres manufactured using an advanced powder metallurgy technique

    NASA Astrophysics Data System (ADS)

    Sazegaran, Hamid; Kiani-Rashid, Ali-Reza; Khaki, Jalil Vahdati

    2016-04-01

    Metallic hollow spheres are used as base materials in the manufacture of hollow sphere structures and metallic foams. In this study, steel hollow spheres were successfully manufactured using an advanced powder metallurgy technique. The spheres' shells were characterized by optical microscopy in conjunction with microstructural image analysis software, scanning electron microscopy (SEM), energy- dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). The microscopic evaluations revealed that the shells consist of sintered iron powder, sintered copper powder, sodium silicate, and porosity regions. In addition, the effects of copper content on various parameters such as shell defects, microcracks, thickness, and porosities were investigated. The results indicated that increasing the copper content results in decreases in the surface fraction of shell porosities and the number of microcracks and an increase in shell thickness.

  19. Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

    PubMed Central

    Koehl, U.; Kalberer, C.; Spanholtz, J.; Lee, D. A.; Miller, J. S.; Cooley, S.; Lowdell, M.; Uharek, L.; Klingemann, H.; Curti, A.; Leung, W.; Alici, E.

    2016-01-01

    ABSTRACT Natural killer (NK) cells are increasingly used in clinical studies in order to treat patients with various malignancies. The following review summarizes platform lectures and 2013–2015 consortium meetings on manufacturing and clinical use of NK cells in Europe and United States. A broad overview of recent pre-clinical and clinical results in NK cell therapies is provided based on unstimulated, cytokine-activated, as well as genetically engineered NK cells using chimeric antigen receptors (CAR). Differences in donor selection, manufacturing and quality control of NK cells for cancer immunotherapies are described and basic recommendations are outlined for harmonization in future NK cell studies. PMID:27141397

  20. Advanced composites structural concepts and materials technologies for primary aircraft structures: Design/manufacturing concept assessment

    NASA Technical Reports Server (NTRS)

    Chu, Robert L.; Bayha, Tom D.; Davis, HU; Ingram, J. ED; Shukla, Jay G.

    1992-01-01

    Composite Wing and Fuselage Structural Design/Manufacturing Concepts have been developed and evaluated. Trade studies were performed to determine how well the concepts satisfy the program goals of 25 percent cost savings, 40 percent weight savings with aircraft resizing, and 50 percent part count reduction as compared to the aluminum Lockheed L-1011 baseline. The concepts developed using emerging technologies such as large scale resin transfer molding (RTM), automatic tow placed (ATP), braiding, out-of-autoclave and automated manufacturing processes for both thermoset and thermoplastic materials were evaluated for possible application in the design concepts. Trade studies were used to determine which concepts carry into the detailed design development subtask.

  1. Principals' Perceptions on the Necessity to Prepare Students for Careers in Advanced Manufacturing

    ERIC Educational Resources Information Center

    Lee, Matthew

    2015-01-01

    The United States (U.S.) is undergoing a paradigm shift in manufacturing as it progresses from an era of low skill employees who stood in one place controlling machines that drilled, stamped, cut, and milled products that passed through the effective and efficient assembly line, to one that is derived from scientific inquiry and technological…

  2. DARPA Agreement HR0011-06-1-0028 (Robert C. Byrd Institute for Advanced Flexible Manufacturing)

    DTIC Science & Technology

    2011-12-13

    assistance to the West Virginia Army National Guard, which included ISO 9001 Quality Management ; ISO 14001 Environmental Management ; Six Sigma Green...Environmental Management Systems implementation and certification including ISO 9001 , ISO 14001; 5S Manufacturing initiatives; Six Sigma; Lean...implemented registered quality management systems for proper documentation to ensure effective suppliers in the supply chain. Beyond compliance or

  3. 76 FR 43983 - Request for Information on How To Structure Proposed New Program: Advanced Manufacturing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... framework (e.g., an industry cluster model) that facilitates regional government and venture capital support... or newly created industry-led consortia to develop precompetitive enabling manufacturing technologies... R&D has shifted toward short-term research. These trends leave industry's long-term needs unmet...

  4. Manufacture and engine test of advanced oxide dispersion strengthened alloy turbine vanes. [for space shuttle thermal protection

    NASA Technical Reports Server (NTRS)

    Bailey, P. G.

    1977-01-01

    Oxide-Dispersion-strengthened (ODS) Ni-Cr-Al alloy systems were exploited for turbine engine vanes which would be used for the space shuttle thermal protection system. Available commercial and developmental advanced ODS alloys were evaluated, and three were selected based on established vane property goals and manufacturing criteria. The selected alloys were evaluated in an engine test. Candidate alloys were screened by strength, thermal fatigue resistance, oxidation and sulfidation resistance. The Ni-16Cr (3 to 5)Al-ThO2 system was identified as having attractive high temperature oxidation resistance. Subsequent work also indicated exceptional sulfidation resistance for these alloys.

  5. Final Technical Report - Center for Technology for Advanced Scientific Component Software (TASCS)

    SciTech Connect

    Sussman, Alan

    2014-10-21

    This is a final technical report for the University of Maryland work in the SciDAC Center for Technology for Advanced Scientific Component Software (TASCS). The Maryland work focused on software tools for coupling parallel software components built using the Common Component Architecture (CCA) APIs. Those tools are based on the Maryland InterComm software framework that has been used in multiple computational science applications to build large-scale simulations of complex physical systems that employ multiple separately developed codes.

  6. Final Report for "Center for Technology for Advanced Scientific Component Software"

    SciTech Connect

    Svetlana Shasharina

    2010-12-01

    The goal of the Center for Technology for Advanced Scientific Component Software is to fundamentally changing the way scientific software is developed and used by bringing component-based software development technologies to high-performance scientific and engineering computing. The role of Tech-X work in TASCS project is to provide an outreach to accelerator physics and fusion applications by introducing TASCS tools into applications, testing tools in the applications and modifying the tools to be more usable.

  7. Development of an advanced uncooled 10-Gb DFB laser for volume manufacture

    NASA Astrophysics Data System (ADS)

    Burns, Gordon; Charles, Paul M.

    2003-03-01

    Optical communication systems operating at 10Gbit/s such as 10Gigabit Ethernet are becoming more and more important in Local Area Networks (LAN) and Metropolitan Area Networks (MAN). This market requires optical transceivers of low cost, size and power consumption. This drives a need for uncooled DFB lasers directly modulated at 10Gbit/s. This paper describes the development of a state of the art uncooled high speed DFB laser which is capable of being manufactured in high volume at the low cost demanded by the GbE market. A DFB laser was designed by developing technological building blocks within the 'conventional" InGaAsP materials system, using existing well proven manufacturing processes modules wherever possible, limiting the design risk to a few key areas where innovation was required. The temperature and speed performance of the InGaAsP SMQW active layer system was carefully optimized and then coupled with a low parasitic lateral confinement system. Using concurrent engineering, new processes were demonstrated to have acceptable process capability within a manufacturing fabrication environment, proving their ability to support high volume manufacturing requirements. The DFB laser fabricated was shown to operate at 100C chip temperature with an open eye at 10Gbit/s operation (with an extinction ratio >5dB). Up to 90C operation this DFB shows threshold current as low as 29mA, optical power as high as 13mW and it meets the 10Gb scaled Ethernet mask with extinction ratio >6dB. It was found that the high temperature dynamic behavior of these lasers could not be fully predicted from static test data. A production test strategy was therefore followed where equipment was designed to fully test devices/subassemblies at 100C and up to 20Gbit/s at key points in the product build. This facilitated the rapid optimisation of product yields upon manufacturing ramp up and minimization of product costs. This state of the art laser is now transferred into volume manufacture.

  8. Patterns of treatment and costs of intermediate and advanced hepatocellular carcinoma management in four Italian centers

    PubMed Central

    Colombo, Giorgio Lorenzo; Cammà, Calogero; Attili, Adolfo Francesco; Ganga, Roberto; Gaeta, Giovanni Battista; Brancaccio, Giuseppina; Franzini, Jean Marie; Volpe, Marco; Turchetti, Giuseppe

    2015-01-01

    Background Hepatocellular carcinoma (HCC) is a severe health condition associated with high hospitalizations and mortality rates, which also imposes a relevant economic burden. Purpose The aim of the present survey is to investigate treatment strategies and related costs for HCC in the intermediate and advanced stages of the disease. Patients and methods The survey was conducted in four Italian centers through structured interviews with physicians. Information regarding the stage of disease, treatments performed, and related health care resource consumption was included in the questionnaire. Direct health care cost per patient associated with the most relevant treatments such as sorafenib, transarterial chemoembolization (TACE), and transarterial radioembolization (TARE) was evaluated. Results Between 2013 and 2014, 285 patients with HCC were treated in the four participating centers; of these, 80 were in intermediate stage HCC (Barcelona Clinic Liver Cancer Classification [BCLC] B), and 57 were in the advanced stage of the disease (BCLC C). In intermediate stage HCC, the most frequent first-line treatment was TACE (63%) followed by sorafenib (15%), radiofrequency ablation (14%), and TARE (1.3%). In the advanced stage of HCC, the most frequently used first-line therapy was sorafenib (56%), followed by best supportive care (21%), TACE (18%), and TARE (3.5%). The total costs of treatment per patient amounted to €12,214.54 with sorafenib, €13,418.49 with TACE, and €26,106.08 with TARE. Both in the intermediate and in the advanced stage of the disease, variability in treatment patterns among centers was observed. Conclusion The present analysis raises for the first time the awareness of the overall costs incurred by the Italian National Healthcare System for different treatments used in intermediate and advanced HCC. Further investigations would be important to better understand the effective health care resource usage. PMID:26527877

  9. Production of general purpose heat source (GPHS) using advanced manufacturing methods

    NASA Astrophysics Data System (ADS)

    Miller, Roger G.

    1996-03-01

    Mankind will continue to explore the stars through the use of unmanned space craft until the technology and costs are compatible with sending travelers to the outer planets of our solar system and beyond. Unmanned probes of the present and future will be necessary to develop the necessary technologies and obtain information that will make this travel possible. Because of the significant costs incurred, the use of modern manufacturing technologies must be used to lower the investment needed even when shared by international partnerships. For over the last 30 years, radioisotopes have provided the heat from which electrical power is extracted. Electric power for future spacecraft will be provided by either Radioisotope Thermoelectric Generators (RTG), Radioisotopic Thermophotovoltaic systems (RTPV), radioisotope Stirling systems, or a combination of these. All of these systems will be thermally driven by General Purpose Heat Source (GPHS) fueled clad in some configuration. The GPHS clad contains a 238PuO2 pellet encapsulated in an iridium alloy container. Historically, the fabrication of the iridium alloy shells has been performed at EG&G Mound and Oak Ridge National Laboratory (ORNL), and girth welding at Westinghouse Savannah River Corporation (WSRC) and Los Alamos National Laboratory (LANL). This paper will describe the use of laser processing for welding, drilling, cutting, and machining with other manufacturing methods to reduce the costs of producing GPHS fueled clad components and compléted assemblies. Incorporation of new quality technologies will compliment these manufacturing methods to reduce cost.

  10. Additive Manufacturing of Advanced High Temperature Masking Fixtures for EBPVD TBC Coating

    SciTech Connect

    List, III, Frederick Alyious; Feuerstein, Albert; Dehoff, Ryan; Kirka, Michael; Carver, Keith

    2016-03-30

    The purpose of this Manufacturing Demonstration Facility (MDF) technical collaboration project between Praxair Surface Technologies, Inc. (PST) and Oak Ridge National Laboratory (ORNL) was to develop an additive manufacturing process to fabricate next generation high temperature masking fixtures for coating of turbine airfoils with ceramic Thermal Barrier Coatings (TBC) by the Electron Beam Physical Vapor Deposition (EBPVD) process. Typical masking fixtures are sophisticated designs and require complex part manipulation in order to achieve the desired coating distribution. Fixtures are typically fabricated from high temperature nickel (Ni) based superalloys. The fixtures are fabricated from conventional processes by welding of thin sheet material into a complex geometry, to decrease the weight load for the manipulator and to reduce the thermal mass of the fixture. Recent attempts have been made in order to fabricate the fixtures through casting, but thin walled sections are difficult to cast and have high scrap rates. This project focused on understanding the potential for fabricating high temperature Ni based superalloy fixtures through additive manufacturing. Two different deposition processes; electron beam melting (EBM) and laser powder bed fusion were evaluated to determine the ideal processing route of these materials. Two different high temperature materials were evaluated. The high temperature materials evaluated were Inconel 718 and another Ni base alloy, designated throughout the remainder of this document as Alloy X, as the alloy composition is sensitive. Inconel 718 is a more widely utilized material for additive manufacturing although it is not currently the material utilized for current fixtures. Alloy X is the alloy currently used for the fixtures, but is not a commercially available alloy for additive manufacturing. Praxair determined it was possible to build the fixture using laser powder bed technology from Inconel 718. ORNL fabricated the fixture

  11. Manufacturing technology

    SciTech Connect

    Blaedel, K.L.

    1997-02-01

    The specific goals of the Manufacturing Technology thrust area are to develop an understanding of fundamental fabrication processes, to construct general purpose process models that will have wide applicability, to document our findings and models in journals, to transfer technology to LLNL programs, industry, and colleagues, and to develop continuing relationships with industrial and academic communities to advance our collective understanding of fabrication processes. Advances in four projects are described here, namely Design of a Precision Saw for Manufacturing, Deposition of Boron Nitride Films via PVD, Manufacturing and Coating by Kinetic Energy Metallization, and Magnet Design and Application.

  12. Advanced Manufacturing Industry Study Group Paper "Getting Agile & Fast - A 2003 Overture to Pre-Eminence"

    DTIC Science & Technology

    2003-01-01

    company that we visited leveraged IT to achieve ‘six sigma’ quality in isolated lean manufacturing assembly lines or manufacturing cells. Even in the...color you want, as long as it’s black.” In this environment, the best manufacturers use lean manufacturing processes to postpone procurement and... lean manufacturing processes, and demand-driven production. Manufacturers are actively rooting out waste in their manufacturing processes and

  13. C-130 Advanced Technology Center wing box conceptual design/cost study

    NASA Technical Reports Server (NTRS)

    Whitehead, R. S.; Foreman, C. R.; Silva, K.

    1992-01-01

    A conceptual design was developed by Northrop/LTV for an advanced C-130 Center Wing Box (CWB) which could meet the severe mission requirements of the SOF C-130 aircraft. The goals for the advanced technology CWB relative to the current C-130H CWB were: (1) the same acquisition cost; (2) lower operating support costs; (3) equal or lower weight; (4) a 30,000 hour service life for the SOF mission; and (5) minimum impact on the current maintenance concept. Initially, the structural arrangement, weight, external and internal loads, fatigue spectrum, flutter envelope and design criteria for the SOF C-130 aircraft CWB were developed. An advanced materials assessment was then conducted to determine the suitability of advanced materials for a 1994 production availability and detailed trade studies were performed on candidate CWB conceptual designs. Finally, a life-cycle cost analysis was performed on the advanced CWB. The study results showed that a hybrid composite/metallic CWB could meet the severe SOF design requirements, reduce the CWB weight by 14 pct., and was cost effective relative to an all metal beefed up C-130H CWB.

  14. Manufacturing of advanced bent crystals for Laue Optics for Gamma ObservationS (LOGOS)

    NASA Astrophysics Data System (ADS)

    Mazzolari, Andrea; Camattari, Riccardo; Bellucci, Valerio; Paternò, Gianfranco; Scian, Carlo; Mattei, Giovanni; Guidi, Vincenzo

    2015-07-01

    X- and γ-ray detection is currently a hot topic for a wide scientific community, spanning from astrophysics to nuclear medicine. However, lack of optics capable of focusing photons of energies in the energy range 0.1-1 MeV leaves the photon detection to a direct-view approach, resulting in a limited efficiency and resolution. The main scope of the INFN-LOGOS project is the development of technologies that enable manufacturing highly performing optical elements to be employed in the realization of hard X-ray lenses. Such lenses, typically named Laue lenses, consist of an ensemble of crystals disposed in concentric rings in order to diffract the incident radiation towards the focus of the lens, where a detector is placed. In particular, the INFN-LOGOS project aims at the realization of intrinsically bent silicon and germanium crystals exploiting the quasi-mosaic effect for focusing hard X-rays. Crystal manufacturing relies on a proper revisitation of techniques typically employed in silicon micromachining, such as thin film deposition and patterning or ion implantation.

  15. Advances in directed self assembly integration and manufacturability at 300 mm

    NASA Astrophysics Data System (ADS)

    Rathsack, Benjamen; Somervell, Mark; Muramatsu, Makato; Tanouchi, Keiji; Kitano, Takahiro; Nishimura, Eiichi; Yatsuda, Koichi; Nagahara, Seiji; Iwaki, Hiroyuki; Akai, Keiji; Ozawa, Mariko; Romo Negreira, Ainhoa; Tahara, Shigeru; Nafus, Kathleen

    2013-03-01

    Directed self-assembly (DSA) has the potential to extend scaling for both line/space and hole patterns. DSA has shown the capability for pitch reduction (multiplication), hole shrinks, CD self-healing as well as a pathway towards LWR and pattern collapse improvement [1-10]. TEL has developed a DSA development ecosystem (collaboration with customers, consortia, inspection vendors and material suppliers) to successfully demonstrate directed PS-PMMA DSA patterns using chemo-epitaxy (lift-off and etch guide) and grapho-epitaxy integrations on 300 mm wafers. New processes are being developed to simplify process integration, to reduce defects and to address design integration challenges with the long term goal of robust manufacturability. For hole DSA applications, a wet development process has been developed that enables traditional post-develop metrology through the high selectivity removal of PMMA cylindrical cores. For line/ space DSA applications, new track, cleans and etch processes have been developed to improve manufacturability. In collaboration with universities and consortia, fundamental process studies and simulations are used to drive process improvement and defect investigation. To extend DSA resolution beyond a PS-PMMA system, high chi materials and processes are also explored. In this paper, TEL's latest process solutions for both hole and line/space DSA process integrations are presented.

  16. Advanced Materials and Manufacturing for Low-Cost, High-Performance Liquid Rocket Combustion Chambers

    NASA Technical Reports Server (NTRS)

    Williams, Brian E.; Arrieta, Victor M.

    2013-01-01

    A document describes the low-cost manufacturing of C103 niobium alloy combustion chambers, and the use of a high-temperature, oxidation-resistant coating that is superior to the standard silicide coating. The manufacturing process involved low-temperature spray deposition of C103 on removable plastic mandrels produced by rapid prototyping. Thin, vapor-deposited platinum-indium coatings were shown to substantially improve oxidation resistance relative to the standard silicide coating. Development of different low-cost plastic thrust chamber mandrel materials and prototyping processes (selective laser sintering and stereolithography) yielded mandrels with good dimensional accuracy (within a couple of mils) for this stage of development. The feasibility of using the kinetic metallization cold-spray process for fabrication of free-standing C1O3 thrusters on removable plastic mandrels was also demonstrated. The ambient and elevated temperature mechanical properties of the material were shown to be reasonably good relative to conventionally processed C103, but the greatest potential benefit is that coldsprayed chambers require minimal post-process machining, resulting in substantially lower machining and material costs. The platinum-iridium coating was shown to provide greatly increased oxidation resistance over the silicide when evaluated through oxyacetylene torch testing to as high as 300 F (= 150 C). The iridium component minimizes reaction with the niobium alloy chamber at high temperatures, and provides the high-temperature oxidation resistance needed at the throat.

  17. Field Evaluation of Advances in Energy-Efficiency Practices for Manufactured Homes

    SciTech Connect

    Levy, E.; Dentz, J.; Ansanelli, E.; Barker, G.; Rath, P.; Dadia, D.

    2016-03-01

    Three side-by-side lab houses were built, instrumented and monitored in an effort to determine through field testing and analysis the relative contributions of select technologies toward reducing energy use in new manufactured homes. The lab houses in Russellville, Alabama compared the performance of three homes built to varying levels of thermal integrity and HVAC equipment: a baseline HUD-code home equipped with an electric furnace and a split system air conditioner; an ENERGY STAR manufactured home with an enhanced thermal envelope and traditional split system heat pump; and a house designed to qualify for Zero Energy Ready Home designation with a ductless mini-split heat pump with transfer fan distribution system in place of the traditional duct system for distribution. Experiments were conducted in the lab houses to evaluate impact on energy and comfort of interior door position, window blind position and transfer fan operation. The report describes results of tracer gas and co-heating tests and presents calculation of the heat pump coefficient of performance for both the traditional heat pump and the ductless mini-split. A series of calibrated energy models was developed based on measured data and run in three locations in the Southeast to compare annual energy usage of the three homes.

  18. Aircrew helmet design and manufacturing enhancements through the use of advanced technologies

    NASA Astrophysics Data System (ADS)

    Cadogan, David P.; George, Alan E.; Winkler, Edward R.

    1993-12-01

    With the development of helmet mounted displays (HMD) and night vision systems (NVS) for use in military and civil aviation roles, new methods of helmet development need to be explored. The helmet must be designed to provide the user with the most lightweight, form fitting system, while meeting other system performance requirements. This can be achieved through a complete analysis of the system requirements. One such technique for systems analysis, a quality function deployment (QFD) matrix, is explored for this purpose. The advanced helmet development process for developing aircrew helmets includes the utilization of several emerging technologies such as laser scanning, computer aided design (CAD), computer generated patterns from 3-D surfaces, laser cutting of patterns and components, and rapid prototyping (stereolithography). Advanced anthropometry methods for helmet development are also available for use. Besides the application of advanced technologies to be used in the development of helmet assemblies, methods of mass reduction are also discussed. The use of these advanced technologies will minimize errors in the development cycle of the helmet and molds, and should enhance system performance while reducing development time and cost.

  19. [Prospect of the Advanced Life Support Program Breadboard Project at Kennedy Space Center in USA].

    PubMed

    Guo, S S; Ai, W D

    2001-04-01

    The Breadboard Project at Kennedy Space Center in NASA of USA was focused on the development of the bioregenerative life support components, crop plants for water, air, and food production and bioreactors for recycling of wastes. The keystone of the Breadboard Project was the Biomass Production Chamber (BPC), which was supported by 15 environmentally controlled chambers and several laboratory facilities holding a total area of 2150 m2. In supporting the Advanced Life Support Program (ALS Program), the Project utilizes these facilities for large-scale testing of components and development of required technologies for human-rated test-beds at Johnson Space Center in NASA, in order to enable a Lunar and a Mars mission finally.

  20. Center for Technology for Advanced Scientific Component Software (TASCS) Consolidated Progress Report July 2006 - March 2009

    SciTech Connect

    Bernholdt, D E; McInnes, L C; Govindaraju, M; Bramley, R; Epperly, T; Kohl, J A; Nieplocha, J; Armstrong, R; Shasharina, S; Sussman, A L; Sottile, M; Damevski, K

    2009-04-14

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  1. Advanced technology needs for a global change science program: Perspective of the Langley Research Center

    NASA Technical Reports Server (NTRS)

    Rowell, Lawrence F.; Swissler, Thomas J.

    1991-01-01

    The focus of the NASA program in remote sensing is primarily the Earth system science and the monitoring of the Earth global changes. One of NASA's roles is the identification and development of advanced sensing techniques, operational spacecraft, and the many supporting technologies necessary to meet the stringent science requirements. Langley Research Center has identified the elements of its current and proposed advanced technology development program that are relevant to global change science according to three categories: sensors, spacecraft, and information system technologies. These technology proposals are presented as one-page synopses covering scope, objective, approach, readiness timeline, deliverables, and estimated funding. In addition, the global change science requirements and their measurement histories are briefly discussed.

  2. Next generation grinding spindle for cost-effective manufacture of advanced ceramic components

    SciTech Connect

    Kovach, J.A.; Laurich, M.A.

    2000-01-01

    Finish grinding of advanced structural ceramics has generally been considered an extremely slow and costly process. Recently, however, results from the High-Speed, Low-Damage (HSLD) program have clearly demonstrated that numerous finish-process performance benefits can be realized by grinding silicon nitride at high wheel speeds. A new, single-step, roughing-process capable of producing high-quality silicon nitride parts at high material removal rates while dramatically reducing finishing costs has been developed.

  3. Advancing LGBT Health at an Academic Medical Center: A Case Study.

    PubMed

    Yehia, Baligh R; Calder, Daniel; Flesch, Judd D; Hirsh, Rebecca L; Higginbotham, Eve; Tkacs, Nancy; Crawford, Beverley; Fishman, Neil

    2015-12-01

    Academic health centers are strategically positioned to impact the health of lesbian, gay, bisexual and transgender (LGBT) populations by advancing science, educating future generations of providers, and delivering integrated care that addresses the unique health needs of the LGBT community. This report describes the early experiences of the Penn Medicine Program for LGBT Health, highlighting the favorable environment that led to its creation, the mission and structure of the Program, strategic planning process used to set priorities and establish collaborations, and the reception and early successes of the Program.

  4. The Recent Revolution in the Design and Manufacture of Cranial Implants: Modern Advancements and Future Directions

    PubMed Central

    Bonda, David J.; Manjila, Sunil; Selman, Warren R.; Dean, David

    2015-01-01

    Large format (i.e., > 25 cm2) cranioplasty is a challenging procedure not only from a cosmesis standpoint, but also in terms of ensuring that the patient's brain will be well-protected from direct trauma. Until recently, when a patient's own cranial flap was unavailable, these goals were unattainable. Recent advances in implant Computer Aided Design and 3-D printing are leveraging other advances in regenerative medicine. It is now possible to 3-D-print patient-specific implants from a variety of polymer, ceramic, or metal components. A skull template may be used to design the external shape of an implant that will become well integrated in the skull, while also providing beneficial distribution of mechanical force distribution in the event of trauma. Furthermore, an internal pore geometry can be utilized to facilitate the seeding of banked allograft cells. Implants may be cultured in a bioreactor along with recombinant growth factors to produce implants coated with bone progenitor cells and extracellular matrix that appear to the body as a graft, albeit a tissue-engineered graft. The growth factors would be left behind in the bioreactor and the graft would resorb as new host bone invades the space and is remodeled into strong bone. As we describe in this review, such advancements will lead to optimal replacement of cranial defects that are both patient-specific and regenerative. PMID:26171578

  5. IMPROVEMENT OF WEAR COMPONENT'S PERFORMANCE BY UTILIZING ADVANCED MATERIALS AND NEW MANUFACTURING TECHNOLOGIES: CASTCON PROCESS FOR MINING APPLICATIONS

    SciTech Connect

    Xiaodi Huang; Richard Gertsch

    2002-08-27

    The project has seen quite a bit of activity in this quarter, highlighted by the fabrication of a bit insert for field testing. In addition: (1) Several alternative process techniques were attempted to prevent bloating, cracking and delamination of FM material that occurs during binder burnout. The approaches included fabrication of FM material by three pass extrusion and warm isostatic pressing of green material, slow and confined burnouts as well as, burnout of thin plate instead of rod stock. Happily, a confined burnout followed by HIPing, produced FM button inserts without bloating or delamination. (2) Four rock bit inserts were produced from FM material and are ready for use on blast hole bits in the field. (3) Six of the project participants from Michigan Technological University, Advanced Ceramic Manufacturing, and The Robbins Group visited the Superior Rock Bit Company in Minnesota and planned the field test of FM inserts.

  6. Spherical fuel elements for advanced HTR manufacture and qualification by irradiation testing

    NASA Astrophysics Data System (ADS)

    Mehner, A.-W.; Heit, W.; Röllig, K.; Ragoss, H.; Müller, H.

    1990-04-01

    The reference fuel cycle for future pebble bed HTRs uses low enriched uranium fuel. The spherical fuel element for these HTRs is a 60 mm diameter sphere containing TRISO-coated particles with UO 2 kernels. Qualification of this fuel was performed by production and quality control experience, irradiation testing and accident simulation experiments. The results of the qualification programme fully support the new safety concepts of advanced HTR designs. Further work concentrates on consolidating performance data sets and on quantifying the endurance limits of reference fuel elements under normal and accident conditions.

  7. South Carolina Center for the Advancement of Teaching and School Leadership: Professional Development Schools. Policy Paper Series 1.3.

    ERIC Educational Resources Information Center

    Gottesman, Barbara; And Others

    In 1990, the South Carolina Center for the Advancement of Teaching and School Leadership was established by the state's legislature to provide support to schools undergoing or planning restructuring. The Center assists schools to analyze needs, establish goals, and implement those goals. Technical assistance and college and school faculty training…

  8. The role of university and college counseling centers in advancing the professionalization of psychology.

    PubMed

    Bingham, Rosie Phillips

    2015-11-01

    Psychologists in university and college counseling centers (UCCCs) have helped to shape and advance the professionalization of psychology. Most definitions of a profession contain at least 5 components. A profession has (1) systematic theories and underlying principles; (2) authority to practice provided by the client; (3) a long educational process, including training and mentoring; (4) standards and a code of ethics; and (5) a culture of service and accountability to the public. UCCC professionals have evolved in a manner that demonstrates all 5 components of a profession. They advance the discipline of psychology as a profession through their counseling interventions because such interventions are based on scientific theories and principles. While their practice rests on scientific principles, their work helps to confirm and modify that science. Authority to practice is evidenced by the continuous growth of counseling centers since World War II. UCCCs aid the extended educational process for psychology graduate students as evidenced by their providing more internship training sites than any other category of training agencies. The majority of UCCC professionals are licensed and must abide by their state code of ethics. Such codes hold psychologists accountable to the public because they regularly deliver counseling service to at least 10% of the campus student population and offer outreach services to many more in their communities.

  9. Advances in computer-aided design and computer-aided manufacture technology.

    PubMed

    Calamia, J R

    1994-01-01

    Although the development of computer-aided design (CAD) and computer-aided manufacture (CAM) technology and the benefits of increased productivity became obvious in the automobile and aerospace industries in the 1970s, investigations of this technology's application in the field of dentistry did not begin until the 1980s. Only now are we beginning to see the fruits of this work with the commercial availability of some systems; the potential for this technology seems boundless. This article reviews the recent literature with emphasis on the period from June 1992 to May 1993. This review should familiarize the reader with some of the latest developments in this technology, including a brief description of some systems currently available and the clinical and economical rationale for their acceptance into the dental mainstream. This article concentrates on a particular system, the Cerec (Siemens/Pelton and Crane, Charlotte, NC) system, for three reasons: first, this system has been available since 1985 and, as a result, has a track record of almost 7 years of data. Most of the data have just recently been released and consequently, much of this year's literature on CAD-CAM is monopolized by studies using this system. Second, this system was developed as a mobile, affordable, direct chairside CAD-CAM restorative method. As such, it is of special interest to the dentist who will offer this new technology directly to the patient, providing a one-visit restoration. Third, the author is currently engaged in research using this particular system and has a working knowledge of this system's capabilities.

  10. Industrialization of Biology. A Roadmap to Accelerate the Advanced Manufacturing of Chemicals

    SciTech Connect

    Friedman, Douglas C.

    2015-09-01

    The report stresses the need for efforts to inform the public of the nature of industrial biotechnology and of its societal benefits, and to make sure that concerns are communicated effectively between the public and other stakeholders. In addition to scientific advances, a number of governance and societal factors will influence the industrialization of biology. Industry norms and standards need to be established in areas such as read/write accuracy for DNA, data and machine technology specifications, and organism performance in terms of production rates and yields. An updated regulatory regime is also needed to accelerate the safe commercialization of new host organisms, metabolic pathways, and chemical products, and regulations should be coordinated across nations to enable rapid, safe, and global access to new technologies and products.

  11. Accomplishments of the Advanced Reusable Technologies (ART) RBCC Project at NASA/Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Nelson, Karl W.; McArthur, J. Craig (Technical Monitor)

    2001-01-01

    The focus of the NASA / Marshall Space Flight Center (MSFC) Advanced Reusable Technologies (ART) project is to advance and develop Rocket-Based Combined-Cycle (RBCC) technologies. The ART project began in 1996 as part of the Advanced Space Transportation Program (ASTP). The project is composed of several activities including RBCC engine ground testing, tool development, vehicle / mission studies, and component testing / development. The major contractors involved in the ART project are Aerojet and Rocketdyne. A large database of RBCC ground test data was generated for the air-augmented rocket (AAR), ramjet, scramjet, and ascent rocket modes of operation for both the Aerojet and Rocketdyne concepts. Transition between consecutive modes was also demonstrated as well as trajectory simulation. The Rocketdyne freejet tests were conducted at GASL in the Flight Acceleration Simulation Test (FAST) facility. During a single test, the FAST facility is capable of simulating both the enthalpy and aerodynamic conditions over a range of Mach numbers in a flight trajectory. Aerojet performed freejet testing in the Pebble Bed facility at GASL as well as direct-connect testing at GASL. Aerojet also performed sea-level static (SLS) testing at the Aerojet A-Zone facility in Sacramento, CA. Several flight-type flowpath components were developed under the ART project. Aerojet designed and fabricated ceramic scramjet injectors. The structural design of the injectors will be tested in a simulated scramjet environment where thermal effects and performance will be assessed. Rocketdyne will be replacing the cooled combustor in the A5 rig with a flight-weight combustor that is near completion. Aerojet's formed duct panel is currently being fabricated and will be tested in the SLS rig in Aerojet's A-Zone facility. Aerojet has already successfully tested a cooled cowl panel in the same facility. In addition to MSFC, other NASA centers have contributed to the ART project as well. Inlet testing

  12. Voxel Advanced Digital-Manufacturing for Earth and Regolith in Space Project

    NASA Technical Reports Server (NTRS)

    Zeitlin, Nancy; Mueller, Robert P.

    2015-01-01

    A voxel is a discrete three-dimensional (3D) element of material that is used to construct a larger 3D object. It is the 3D equivalent of a pixel. This project will conceptualize and study various approaches in order to develop a proof of concept 3D printing device that utilizes regolith as the material of the voxels. The goal is to develop a digital printer head capable of placing discrete self-aligning voxels in additive layers in order to fabricate small parts that can be given structural integrity through a post-printing sintering or other binding process. The quicker speeds possible with the voxel 3D printing approach along with the utilization of regolith material as the substrate will advance the use of this technology to applications for In-Situ Resource Utilization (ISRU), which is key to reducing logistics from Earth to Space, thus making long-duration human exploration missions to other celestial bodies more possible.

  13. The Advanced High-Temperature Reactor (AHTR) for Producing Hydrogen to Manufacture Liquid Fuels

    SciTech Connect

    Forsberg, C.W.; Peterson, P.F.; Ott, L.

    2004-10-06

    Conventional world oil production is expected to peak within a decade. Shortfalls in production of liquid fuels (gasoline, diesel, and jet fuel) from conventional oil sources are expected to be offset by increased production of fuels from heavy oils and tar sands that are primarily located in the Western Hemisphere (Canada, Venezuela, the United States, and Mexico). Simultaneously, there is a renewed interest in liquid fuels from biomass, such as alcohol; but, biomass production requires fertilizer. Massive quantities of hydrogen (H2) are required (1) to convert heavy oils and tar sands to liquid fuels and (2) to produce fertilizer for production of biomass that can be converted to liquid fuels. If these liquid fuels are to be used while simultaneously minimizing greenhouse emissions, nonfossil methods for the production of H2 are required. Nuclear energy can be used to produce H2. The most efficient methods to produce H2 from nuclear energy involve thermochemical cycles in which high-temperature heat (700 to 850 C) and water are converted to H2 and oxygen. The peak nuclear reactor fuel and coolant temperatures must be significantly higher than the chemical process temperatures to transport heat from the reactor core to an intermediate heat transfer loop and from the intermediate heat transfer loop to the chemical plant. The reactor temperatures required for H2 production are at the limits of practical engineering materials. A new high-temperature reactor concept is being developed for H2 and electricity production: the Advanced High-Temperature Reactor (AHTR). The fuel is a graphite-matrix, coated-particle fuel, the same type that is used in modular high-temperature gas-cooled reactors (MHTGRs). The coolant is a clean molten fluoride salt with a boiling point near 1400 C. The use of a liquid coolant, rather than helium, reduces peak reactor fuel and coolant temperatures 100 to 200 C relative to those of a MHTGR. Liquids are better heat transfer fluids than gases

  14. Advances in Engine Test Capabilities at the NASA Glenn Research Center's Propulsion Systems Laboratory

    NASA Technical Reports Server (NTRS)

    Pachlhofer, Peter M.; Panek, Joseph W.; Dicki, Dennis J.; Piendl, Barry R.; Lizanich, Paul J.; Klann, Gary A.

    2006-01-01

    The Propulsion Systems Laboratory at the National Aeronautics and Space Administration (NASA) Glenn Research Center is one of the premier U.S. facilities for research on advanced aeropropulsion systems. The facility can simulate a wide range of altitude and Mach number conditions while supplying the aeropropulsion system with all the support services necessary to operate at those conditions. Test data are recorded on a combination of steady-state and highspeed data-acquisition systems. Recently a number of upgrades were made to the facility to meet demanding new requirements for the latest aeropropulsion concepts and to improve operational efficiency. Improvements were made to data-acquisition systems, facility and engine-control systems, test-condition simulation systems, video capture and display capabilities, and personnel training procedures. This paper discusses the facility s capabilities, recent upgrades, and planned future improvements.

  15. Testing of the Advanced Stirling Radioisotope Generator Engineering Unit at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Lewandowski, Edward J.

    2013-01-01

    The Advanced Stirling Radioisotope Generator (ASRG) is a high-efficiency generator being developed for potential use on a Discovery 12 space mission. Lockheed Martin designed and fabricated the ASRG Engineering Unit (EU) under contract to the Department of Energy. This unit was delivered to NASA Glenn Research Center in 2008 and has been undergoing extended operation testing to generate long-term performance data for an integrated system. It has also been used for tests to characterize generator operation while varying control parameters and system inputs, both when controlled with an alternating current (AC) bus and with a digital controller. The ASRG EU currently has over 27,000 hours of operation. This paper summarizes all of the tests that have been conducted on the ASRG EU over the past 3 years and provides an overview of the test results and what was learned.

  16. Examining the Role of Gender in Career Advancement at the Centers for Disease Control and Prevention

    PubMed Central

    Roy, Kakoli; Gotway Crawford, Carol A.

    2010-01-01

    During the past decade, efforts to promote gender parity in the healing and public health professions have met with only partial success. We provide a critical update regarding the status of women in the public health profession by exploring gender-related differences in promotion rates at the nation's leading public health agency, the Centers for Disease Control and Prevention (CDC). Using personnel data drawn from CDC, we found that the gender gap in promotion has diminished across time and that this reduction can be attributed to changes in individual characteristics (e.g., higher educational levels and more federal work experience). However, a substantial gap in promotion that cannot be explained by such characteristics has persisted, indicating continuing barriers in women's career advancement. PMID:20075327

  17. Examining the role of gender in career advancement at the Centers for Disease Control and Prevention.

    PubMed

    Chen, Zhuo; Roy, Kakoli; Gotway Crawford, Carol A

    2010-03-01

    During the past decade, efforts to promote gender parity in the healing and public health professions have met with only partial success. We provide a critical update regarding the status of women in the public health profession by exploring gender-related differences in promotion rates at the nation's leading public health agency, the Centers for Disease Control and Prevention (CDC). Using personnel data drawn from CDC, we found that the gender gap in promotion has diminished across time and that this reduction can be attributed to changes in individual characteristics (e.g., higher educational levels and more federal work experience). However, a substantial gap in promotion that cannot be explained by such characteristics has persisted, indicating continuing barriers in women's career advancement.

  18. Manufacturing of Protected Lithium Electrodes for Advanced Lithium-Air, Lithium-Water & Lithium-Sulfur Batteries

    SciTech Connect

    Visco, Steven J

    2015-11-30

    The global demand for rechargeable batteries is large and growing rapidly. Assuming the adoption of electric vehicles continues to increase, the need for smaller, lighter, and less expensive batteries will become even more pressing. In this vein, PolyPlus Battery Company has developed ultra-light high performance batteries based on its proprietary protected lithium electrode (PLE) technology. The Company’s Lithium-Air and Lithium-Seawater batteries have already demonstrated world record performance (verified by third party testing), and we are developing advanced lithium-sulfur batteries which have the potential deliver high performance at low cost. In this program PolyPlus Battery Company teamed with Corning Incorporated to transition the PLE technology from bench top fabrication using manual tooling to a pre- commercial semi-automated pilot line. At the inception of this program PolyPlus worked with a Tier 1 battery manufacturing engineering firm to design and build the first-of-its-kind pilot line for PLE production. The pilot line was shipped and installed in Berkeley, California several months after the start of the program. PolyPlus spent the next two years working with and optimizing the pilot line and now produces all of its PLEs on this line. The optimization process successfully increased the yield, throughput, and quality of PLEs produced on the pilot line. The Corning team focused on fabrication and scale-up of the ceramic membranes that are key to the PLE technology. PolyPlus next demonstrated that it could take Corning membranes through the pilot line process to produce state-of-the-art protected lithium electrodes. In the latter part of the program the Corning team developed alternative membranes targeted for the large rechargeable battery market. PolyPlus is now in discussions with several potential customers for its advanced PLE-enabled batteries, and is building relationships and infrastructure for the transition into manufacturing. It is likely

  19. Crop Production for Advanced Life Support Systems - Observations From the Kennedy Space Center Breadboard Project

    NASA Technical Reports Server (NTRS)

    Wheeler, R. M.; Sager, J. C.; Prince, R. P.; Knott, W. M.; Mackowiak, C. L.; Stutte, G. W.; Yorio, N. C.; Ruffe, L. M.; Peterson, B. V.; Goins, G. D.

    2003-01-01

    The use of plants for bioregenerative life support for space missions was first studied by the US Air Force in the 1950s and 1960s. Extensive testing was also conducted from the 1960s through the 1980s by Russian researchers located at the Institute of Biophysics in Krasnoyarsk, Siberia, and the Institute for Biomedical Problems in Moscow. NASA initiated bioregenerative research in the 1960s (e.g., Hydrogenomonas) but this research did not include testing with plants until about 1980, with the start of the Controlled Ecological Life Support System (CELSS) Program. The NASA CELSS research was carried out at universities, private corporations, and NASA field centers, including Kennedy Space Center (KSC). The project at KSC began in 1985 and was called the CELSS Breadboard Project to indicate the capability for plugging in and testing various life support technologies; this name has since been dropped but bioregenerative testing at KSC has continued to the present under the NASA s Advanced Life Support (ALS) Program. A primary objective of the KSC testing was to conduct pre-integration tests with plants (crops) in a large, atmospherically closed test chamber called the Biomass Production Chamber (BPC). Test protocols for the BPC were based on observations and growing procedures developed by university investigators, as well as procedures developed in plant growth chamber studies at KSC. Growth chamber studies to support BPC testing focused on plant responses to different carbon dioxide (CO2) concentrations, different spectral qualities from various electric lamps, and nutrient film hydroponic culture techniques.

  20. Center to Advance Palliative Care palliative care clinical care and customer satisfaction metrics consensus recommendations.

    PubMed

    Weissman, David E; Morrison, R Sean; Meier, Diane E

    2010-02-01

    Data collection and analysis are vital for strategic planning, quality improvement, and demonstration of palliative care program impact to hospital administrators, private funders and policymakers. Since 2000, the Center to Advance Palliative Care (CAPC) has provided technical assistance to hospitals, health systems and hospices working to start, sustain, and grow nonhospice palliative care programs. CAPC convened a consensus panel in 2008 to develop recommendations for specific clinical and customer metrics that programs should track. The panel agreed on four key domains of clinical metrics and two domains of customer metrics. Clinical metrics include: daily assessment of physical/psychological/spiritual symptoms by a symptom assessment tool; establishment of patient-centered goals of care; support to patient/family caregivers; and management of transitions across care sites. For customer metrics, consensus was reached on two domains that should be tracked to assess satisfaction: patient/family satisfaction, and referring clinician satisfaction. In an effort to ensure access to reliably high-quality palliative care data throughout the nation, hospital palliative care programs are encouraged to collect and report outcomes for each of the metric domains described here.

  1. Fulvestrant in advanced breast cancer following tamoxifen and aromatase inhibition: a single center experience.

    PubMed

    Wang, Jayson; Jain, Sandeep; Coombes, Charles R; Palmieri, Carlo

    2009-01-01

    Fulvestrant is a pure estrogen receptor (ER) antagonist with no agonist effects. We describe the experience of a single center involving 45 postmenopausal women with advanced breast cancer where fulvestrant was utilized following progression on tamoxifen and a third generation aromatase inhibitor. Patients received fulvestrant as first line one (2%), second line 18 (40%), third line 13 (29%), fourth line 10 (22%), and fifth line three (7%) treatment. Median duration of treatment with Fulvestrant was 4 months (range 1-20 months). One patient had a partial response, 14 other (31%) experienced clinical benefit (CB) (defined as response or stable disease for at least 6 months). The median time to progression (TTP) from initiation of fulvestrant was 4 months (range 1-20 months) and the median survival was 10 months (range 1-55 months). In those patients who experienced CB the median TTP was 10 months (range 6-20) and median survival was 21 months (range 7-55). Fulvestrant was well tolerated; two patients experienced side effects severe enough to stop therapy. Despite the fact that fulvestrant was used in the majority of cases, later in the treatment sequence CB was seen in a number of patients. This data suggest fulvestrant is well tolerated and is a useful treatment option in patients with advanced breast cancer who progress on prior endocrine treatment.

  2. An Overview of Advanced Elastomeric Seal Development and Testing Capabilities at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Dunlap, Patrick H.

    2014-01-01

    NASA is developing advanced space-rated elastomeric seals to support future space exploration missions to low Earth orbit, the Moon, near Earth asteroids, and other destinations. This includes seals for a new docking system and vehicle hatches. These seals must exhibit extremely low leak rates to ensure that astronauts have sufficient breathable air for extended missions. Seal compression loads must be below prescribed limits so as not to overload the mechanisms that compress them, and seal adhesion forces must be low to allow the sealed interface to be separated when required (e.g., during undocking or hatch opening). NASA Glenn Research Center has developed a number of unique test fixtures to measure the leak rates and compression and adhesion loads of candidate seal designs under simulated thermal, vacuum, and engagement conditions. Tests can be performed on full-scale seals with diameters on the order of 50 in., subscale seals that are about 12 in. in diameter, and smaller specimens such as O-rings. Test conditions include temperatures ranging from -238 to 662 F (-150 to 350 C), operational pressure gradients, and seal-on-seal or seal-on-flange mating configurations. Nominal and off-nominal conditions (e.g., incomplete seal compression) can also be simulated. This paper describes the main design features and capabilities of each type of test apparatus and provides an overview of advanced seal development activities at NASA Glenn.

  3. NASA Glenn Research Center Support of the Advanced Stirling Radioisotope Generator Project

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Wong, Wayne A.

    2015-01-01

    A high-efficiency radioisotope power system was being developed for long-duration NASA space science missions. The U.S. Department of Energy (DOE) managed a flight contract with Lockheed Martin Space Systems Company to build Advanced Stirling Radioisotope Generators (ASRGs), with support from NASA Glenn Research Center. DOE initiated termination of that contract in late 2013, primarily due to budget constraints. Sunpower, Inc., held two parallel contracts to produce Advanced Stirling Convertors (ASCs), one with Lockheed Martin to produce ASC-F flight units, and one with Glenn for the production of ASC-E3 engineering unit "pathfinders" that are built to the flight design. In support of those contracts, Glenn provided testing, materials expertise, Government-furnished equipment, inspection capabilities, and related data products to Lockheed Martin and Sunpower. The technical support included material evaluations, component tests, convertor characterization, and technology transfer. Material evaluations and component tests were performed on various ASC components in order to assess potential life-limiting mechanisms and provide data for reliability models. Convertor level tests were conducted to characterize performance under operating conditions that are representative of various mission conditions. Despite termination of the ASRG flight development contract, NASA continues to recognize the importance of high-efficiency ASC power conversion for Radioisotope Power Systems (RPS) and continues investment in the technology, including the continuation of the ASC-E3 contract. This paper describes key Government support for the ASRG project and future tests to be used to provide data for ongoing reliability assessments.

  4. Test Rack Development for Extended Operation of Advanced Stirling Convertors at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.

    2010-01-01

    The U.S. Department of Energy, Lockheed Martin Space Systems Company, Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions. This generator will make use of free-piston Stirling convertors to achieve higher conversion efficiency than with currently available alternatives. One part of NASA GRC's support of ASRG development includes extended operation testing of Advanced Stirling Convertors (ASCs) developed by Sunpower Inc. and GRC. The ASC consists of a free-piston Stirling engine integrated with a linear alternator. NASA GRC has been building test facilities to support extended operation of the ASCs for several years. Operation of the convertors in the test facility provides convertor performance data over an extended period of time. One part of the test facility is the test rack, which provides a means for data collection, convertor control, and safe operation. Over the years, the test rack requirements have changed. The initial ASC test rack utilized an alternating-current (AC) bus for convertor control; the ASRG Engineering Unit (EU) test rack can operate with AC bus control or with an ASC Control Unit (ACU). A new test rack is being developed to support extended operation of the ASC-E2s with higher standards of documentation, component selection, and assembly practices. This paper discusses the differences among the ASC, ASRG EU, and ASC-E2 test racks.

  5. Test Rack Development for Extended Operation of Advanced Stirling Convertors at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.

    2009-01-01

    The U.S. Department of Energy (DOE), Lockheed Martin Space Company (LMSC), Sun power Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions. This generator will make use of free-piston Stirling convertors to achieve higher conversion efficiency than currently available alternatives. NASA GRC's support of ASRG development includes extended operation testing of Advanced Stirling Convertors (ASCs) developed by Sunpower Inc. In the past year, NASA GRC has been building a test facility to support extended operation of a pair of engineering level ASCs. Operation of the convertors in the test facility provides convertor performance data over an extended period of time. Mechanical support hardware, data acquisition software, and an instrumentation rack were developed to prepare the pair of convertors for continuous extended operation. Short-term tests were performed to gather baseline performance data before extended operation was initiated. These tests included workmanship vibration, insulation thermal loss characterization, low-temperature checkout, and fUll-power operation. Hardware and software features are implemented to ensure reliability of support systems. This paper discusses the mechanical support hardware, instrumentation rack, data acquisition software, short-term tests, and safety features designed to support continuous unattended operation of a pair of ASCs.

  6. An Overview of Advanced Elastomeric Seal Development and Testing Capabilities at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Dunlap, Patrick H., Jr.

    2014-01-01

    NASA is developing advanced space-rated elastomeric seals to support future space exploration missions to low Earth orbit, the Moon, near Earth asteroids, and other destinations. This includes seals for a new docking system and vehicle hatches. These seals must exhibit extremely low leak rates to ensure that astronauts have sufficient breathable air for extended missions. Seal compression loads must be below prescribed limits so as not to overload the mechanisms that compress them, and seal adhesion forces must be low to allow the sealed interface to be separated when required (e.g., during undocking or hatch opening). NASA Glenn Research Center has developed a number of unique test fixtures to measure the leak rates and compression and adhesion loads of candidate seal designs under simulated thermal, vacuum, and engagement conditions. Tests can be performed on full-scale seals with diameters on the order of 50 in., subscale seals that are about 12 in. in diameter, and smaller specimens such as O-rings. Test conditions include temperatures ranging from -238 to +662F (-150 to +350C), operational pressure gradients, and seal-on-seal or seal-on-flange mating configurations. Nominal and off-nominal conditions (e.g., incomplete seal compression) can also be simulated. This paper describes the main design features and capabilities of each test apparatus and provides an overview of advanced seal development activities at NASA Glenn.

  7. An Overview of Advanced Elastomeric Seal Development and Testing Capabilities at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Dunlap, Patrick H., Jr.

    2014-01-01

    NASA is developing advanced space-rated elastomeric seals to support future space exploration missions to low Earth orbit, the Moon, near Earth asteroids, and other destinations. This includes seals for a new docking system and vehicle hatches. These seals must exhibit extremely low leak rates to ensure that astronauts have sufficient breathable air for extended missions. Seal compression loads must be below prescribed limits so as not to overload the mechanisms that compress them, and seal adhesion forces must be low to allow the sealed interface to be separated when required (e.g., during undocking or hatch opening). NASA Glenn Research Center has developed a number of unique test fixtures to measure the leak rates and compression and adhesion loads of candidate seal designs under simulated thermal, vacuum, and engagement conditions. Tests can be performed on fullscale seals with diameters on the order of 50 in., subscale seals that are about 12 in. in diameter, and smaller specimens such as O-rings. Test conditions include temperatures ranging from -238 to 662degF (-150 to 350degC), operational pressure gradients, and seal-on-seal or seal-on-flange mating configurations. Nominal and off-nominal conditions (e.g., incomplete seal compression) can also be simulated. This paper describes the main design features and capabilities of each type of test apparatus and provides an overview of advanced seal development activities at NASA Glenn.

  8. Test Platform for Advanced Digital Control of Brushless DC Motors (MSFC Center Director's Discretionary Fund)

    NASA Technical Reports Server (NTRS)

    Gwaltney, D. A.

    2002-01-01

    A FY 2001 Center Director's Discretionary Fund task to develop a test platform for the development, implementation. and evaluation of adaptive and other advanced control techniques for brushless DC (BLDC) motor-driven mechanisms is described. Important applications for BLDC motor-driven mechanisms are the translation of specimens in microgravity experiments and electromechanical actuation of nozzle and fuel valves in propulsion systems. Motor-driven aerocontrol surfaces are also being utilized in developmental X vehicles. The experimental test platform employs a linear translation stage that is mounted vertically and driven by a BLDC motor. Control approaches are implemented on a digital signal processor-based controller for real-time, closed-loop control of the stage carriage position. The goal of the effort is to explore the application of advanced control approaches that can enhance the performance of a motor-driven actuator over the performance obtained using linear control approaches with fixed gains. Adaptive controllers utilizing an exact model knowledge controller and a self-tuning controller are implemented and the control system performance is illustrated through the presentation of experimental results.

  9. Processing and Preparation of Advanced Stirling Convertors for Extended Operation at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Oriti, Salvatore M.; Cornell, Peggy A.

    2008-01-01

    The U.S. Department of Energy (DOE), Lockheed Martin Space Company (LMSC), Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions. This generator will make use of the free-piston Stirling convertors to achieve higher conversion efficiency than currently available alternatives. NASA GRC is supporting the development of the ASRG by providing extended operation of several Sunpower Inc. Advanced Stirling Convertors (ASCs). In the past year and a half, eight ASCs have operated in continuous, unattended mode in both air and thermal vacuum environments. Hardware, software, and procedures were developed to prepare each convertor for extended operation with intended durations on the order of tens of thousands of hours. Steps taken to prepare a convertor for long-term operation included geometry measurements, thermocouple instrumentation, evaluation of working fluid purity, evacuation with bakeout, and high purity charge. Actions were also taken to ensure the reliability of support systems, such as data acquisition and automated shutdown checkouts. Once a convertor completed these steps, it underwent short-term testing to gather baseline performance data before initiating extended operation. These tests included insulation thermal loss characterization, low-temperature checkout, and full-temperature and power demonstration. This paper discusses the facilities developed to support continuous, unattended operation, and the processing results of the eight ASCs currently on test.

  10. Meaning-centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial

    PubMed Central

    Breitbart, William; Rosenfeld, Barry; Gibson, Christopher; Pessin, Hayley; Poppito, Shannon; Nelson, Christian; Tomarken, Alexis; Timm, Anne Kosinski; Berg, Amy; Jacobson, Colleen; Sorger, Brooke; Abbey, Jennifer; Olden, Megan

    2013-01-01

    Objectives An increasingly important concern for clinicians who care for patients at the end of life is their spiritual well-being and sense of meaning and purpose in life. In response to the need for short-term interventions to address spiritual well-being, we developed Meaning Centered Group Psychotherapy (MCGP) to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose in their lives, even as they approach the end of life. Methods Patients with advanced (stage III or IV) solid tumor cancers (N = 90) were randomly assigned to either MCGP or a supportive group psychotherapy (SGP). Patients were assessed before and after completing the 8-week intervention, and again 2 months after completion. Outcome assessment included measures of spiritual well-being, meaning, hopelessness, desire for death, optimism/pessimism, anxiety, depression and overall quality of life. Results MCGP resulted in significantly greater improvements in spiritual well-being and a sense of meaning. Treatment gains were even more substantial (based on effect size estimates) at the second follow-up assessment. Improvements in anxiety and desire for death were also significant (and increased over time). There was no significant improvement on any of these variables for patients participating in SGP. Conclusions MCGP appears to be a potentially beneficial intervention for patients’ emotional and spiritual suffering at the end of life. Further research, with larger samples, is clearly needed to better understand the potential benefits of this novel intervention. PMID:19274623

  11. Technology Transfer: Federal Efforts to Enhance the Competitiveness of Small Manufacturers

    DTIC Science & Technology

    1991-11-01

    manufacturers , we visited each of these MTCS to interview "* MTC officials; "* state technology extension officials in Ohio, New York, and South Caro- lina to...three centers located in Cleveland, Ohio; Troy, New York; and Columbia, South Carolina. All three centers initially proposed to transfer advanced...Competing in Manufacturing (Feb. 1990). 3Economic Policy Institute, Modernizing Manufacturing : New Policies to Build Industrial Extension Services

  12. Pilot Randomized Controlled Trial of Individual Meaning-Centered Psychotherapy for Patients With Advanced Cancer

    PubMed Central

    Breitbart, William; Poppito, Shannon; Rosenfeld, Barry; Vickers, Andrew J.; Li, Yuelin; Abbey, Jennifer; Olden, Megan; Pessin, Hayley; Lichtenthal, Wendy; Sjoberg, Daniel; Cassileth, Barrie R.

    2012-01-01

    Purpose Spiritual well-being and sense of meaning are important concerns for clinicians who care for patients with cancer. We developed Individual Meaning-Centered Psychotherapy (IMCP) to address the need for brief interventions targeting spiritual well-being and meaning for patients with advanced cancer. Patients and Methods Patients with stage III or IV cancer (N = 120) were randomly assigned to seven sessions of either IMCP or therapeutic massage (TM). Patients were assessed before and after completing the intervention and 2 months postintervention. Primary outcome measures assessed spiritual well-being and quality of life; secondary outcomes included anxiety, depression, hopelessness, symptom burden, and symptom-related distress. Results Of the 120 participants randomly assigned, 78 (65%) completed the post-treatment assessment and 67 (56%) completed the 2-month follow-up. At the post-treatment assessment, IMCP participants demonstrated significantly greater improvement than the control condition for the primary outcomes of spiritual well-being (b = 0.39; P <.001, including both components of spiritual well-being (sense of meaning: b = 0.34; P = .003 and faith: b = 0.42; P = .03), and quality of life (b = 0.76; P = .013). Significantly greater improvements for IMCP patients were also observed for the secondary outcomes of symptom burden (b = −6.56; P < .001) and symptom-related distress (b = −0.47; P < .001) but not for anxiety, depression, or hopelessness. At the 2-month follow-up assessment, the improvements observed for the IMCP group were no longer significantly greater than those observed for the TM group. Conclusion IMCP has clear short-term benefits for spiritual suffering and quality of life in patients with advanced cancer. Clinicians working with patients who have advanced cancer should consider IMCP as an approach to enhance quality of life and spiritual well-being. PMID:22370330

  13. Role of RIS/APC for manufacturing RFG/LSD. [Refinery Information Systems/Advanced Process Control, ReFormulated Gasoline/Low Sulfur Diesels

    SciTech Connect

    Latour, P.R. )

    1994-01-01

    Revolutionary changes in quality specifications (number, complexity, uncertainty, economic sensitivity) for reformulated gasolines (RFG) and low-sulfur diesels (LSD) are being addressed by powerful, new, computer-integrated manufacturing technology for Refinery Information Systems and Advanced Process Control (RIS/APC). This paper shows how the five active RIS/APC functions: performance measurement, optimization, scheduling, control and integration are used to manufacture new, clean fuels competitively. With current industry spending for this field averaging 2 to 3 cents/bbl crude, many refineries can capture 50 to 100 cents/bbl if the technology is properly employed and sustained throughout refining operations, organizations, and businesses.

  14. The mobilize center: an NIH big data to knowledge center to advance human movement research and improve mobility.

    PubMed

    Ku, Joy P; Hicks, Jennifer L; Hastie, Trevor; Leskovec, Jure; Ré, Christopher; Delp, Scott L

    2015-11-01

    Regular physical activity helps prevent heart disease, stroke, diabetes, and other chronic diseases, yet a broad range of conditions impair mobility at great personal and societal cost. Vast amounts of data characterizing human movement are available from research labs, clinics, and millions of smartphones and wearable sensors, but integration and analysis of this large quantity of mobility data are extremely challenging. The authors have established the Mobilize Center (http://mobilize.stanford.edu) to harness these data to improve human mobility and help lay the foundation for using data science methods in biomedicine. The Center is organized around 4 data science research cores: biomechanical modeling, statistical learning, behavioral and social modeling, and integrative modeling. Important biomedical applications, such as osteoarthritis and weight management, will focus the development of new data science methods. By developing these new approaches, sharing data and validated software tools, and training thousands of researchers, the Mobilize Center will transform human movement research.

  15. The mobilize center: an NIH big data to knowledge center to advance human movement research and improve mobility

    PubMed Central

    Ku, Joy P; Hicks, Jennifer L; Hastie, Trevor; Leskovec, Jure; Ré, Christopher

    2015-01-01

    Regular physical activity helps prevent heart disease, stroke, diabetes, and other chronic diseases, yet a broad range of conditions impair mobility at great personal and societal cost. Vast amounts of data characterizing human movement are available from research labs, clinics, and millions of smartphones and wearable sensors, but integration and analysis of this large quantity of mobility data are extremely challenging. The authors have established the Mobilize Center (http://mobilize.stanford.edu) to harness these data to improve human mobility and help lay the foundation for using data science methods in biomedicine. The Center is organized around 4 data science research cores: biomechanical modeling, statistical learning, behavioral and social modeling, and integrative modeling. Important biomedical applications, such as osteoarthritis and weight management, will focus the development of new data science methods. By developing these new approaches, sharing data and validated software tools, and training thousands of researchers, the Mobilize Center will transform human movement research. PMID:26272077

  16. Advanced Battery Manufacturing (VA)

    SciTech Connect

    Stratton, Jeremy

    2012-09-30

    LiFeBATT has concentrated its recent testing and evaluation on the safety of its batteries. There appears to be a good margin of safety with respect to overheating of the cells and the cases being utilized for the batteries are specifically designed to dissipate any heat built up during charging. This aspect of LiFeBATT’s products will be even more fully investigated, and assuming ongoing positive results, it will become a major component of marketing efforts for the batteries. LiFeBATT has continued to receive prismatic 20 Amp hour cells from Taiwan. Further testing continues to indicate significant advantages over the previously available 15 Ah cells. Battery packs are being assembled with battery management systems in the Danville facility. Comprehensive tests are underway at Sandia National Laboratory to provide further documentation of the advantages of these 20 Ah cells. The company is pursuing its work with Hybrid Vehicles of Danville to critically evaluate the 20 Ah cells in a hybrid, armored vehicle being developed for military and security applications. Results have been even more encouraging than they were initially. LiFeBATT is expanding its work with several OEM customers to build a worldwide distribution network. These customers include a major automotive consulting group in the U.K., an Australian maker of luxury off-road campers, and a number of makers of E-bikes and scooters. LiFeBATT continues to explore the possibility of working with nations that are woefully short of infrastructure. Negotiations are underway with Siemens to jointly develop a system for using photovoltaic generation and battery storage to supply electricity to communities that are not currently served adequately. The IDA has continued to monitor the progress of LiFeBATT’s work to ensure that all funds are being expended wisely and that matching funds will be generated as promised. The company has also remained current on all obligations for repayment of an IDA loan and lease payments for space to the IDA. A commercial venture is being formed to utilize the LiFeBATT product for consumer use in enabling photovoltaic powered boat lifts. Field tests of the system have proven to be very effective and commercially promising. This venture is expected to result in significant sales within the next six months.

  17. Advanced Technologies for Future Spacecraft Cockpits and Space-based Control Centers

    NASA Technical Reports Server (NTRS)

    Garcia-Galan, Carlos; Uckun, Serdar; Gregory, William; Williams, Kerry

    2006-01-01

    The National Aeronautics and Space Administration (NASA) is embarking on a new era of Space Exploration, aimed at sending crewed spacecraft beyond Low Earth Orbit (LEO), in medium and long duration missions to the Lunar surface, Mars and beyond. The challenges of such missions are significant and will require new technologies and paradigms in vehicle design and mission operations. Current roles and responsibilities of spacecraft systems, crew and the flight control team, for example, may not be sustainable when real-time support is not assured due to distance-induced communication lags, radio blackouts, equipment failures, or other unexpected factors. Therefore, technologies and applications that enable greater Systems and Mission Management capabilities on-board the space-based system will be necessary to reduce the dependency on real-time critical Earth-based support. The focus of this paper is in such technologies that will be required to bring advance Systems and Mission Management capabilities to space-based environments where the crew will be required to manage both the systems performance and mission execution without dependence on the ground. We refer to this concept as autonomy. Environments that require high levels of autonomy include the cockpits of future spacecraft such as the Mars Exploration Vehicle, and space-based control centers such as a Lunar Base Command and Control Center. Furthermore, this paper will evaluate the requirements, available technology, and roadmap to enable full operational implementation of onboard System Health Management, Mission Planning/re-planning, Autonomous Task/Command Execution, and Human Computer Interface applications. The technology topics covered by the paper include enabling technology to perform Intelligent Caution and Warning, where the systems provides directly actionable data for human understanding and response to failures, task automation applications that automate nominal and Off-nominal task execution based

  18. Instrumentation for synchrotron based micromachining at the Center for Advanced Microstructures and Devices (abstract)

    NASA Astrophysics Data System (ADS)

    Aigeldinger, G.; Goettert, J.; Desta, Y.; Ling, Z. L.; Rupp, L.

    2002-03-01

    The J. Bennett Johnston Sr., Center for Advanced Microstructures and Devices (CAMD) is a synchrotron radiation facility owned by Louisiana State University and operated with financial support from the State of Louisiana (for information how to submit a project proposal go to: http://www.camd.lsu.edu). The centerpiece of CAMD is a 1.3-1.5 GeV electron storage ring. CAMD supports a strong program in x-ray lithography micromachining (XRLM) or LIGA. A total of four beamlines equipped with different scanners is available for exposures. A 2.500 sq. ft class 100 clean room provides basic processing capability for MEMS including optical lithography, thin film deposition, electroplating, and metrology. Three micromachining beamlines are connected to bending magnets. All beamlines are "white light" beamlines, terminated with a beryllium window. The typical source point to scanner distance is 10 m and the horizontal acceptance ranges from 6.5 to 10 mrad. A number of low Z filters can be inserted into the beam adapting the exposure spectrum to the resist thickness. Two beamlines are equipped with commercial scanners from Jenoptik GmbH (for details see Jenoptik's webpage at www.jo-mikrotechnik.com/) and one beamline with a "vacuum" scanner designed in house. The latest model of Jenoptik's DEX02 scanner has been installed at CAMD's XRLM1 beamline in December 2000 and allows advanced exposures using overlay as well as tilt and rotate functions. In addition to these beamlines CAMD has installed a "white light" beamline at its 7 T wiggler source. Preliminary exposure tests in ultrathick samples (1 mm and thicker) have been conducted using an "air scanner." Currently this beamline is dismantled and will be reinstalled together with a PX beamline. In the article further details of the beamlines and scanners as well as some examples of applications of LIGA microstructures fabricated at CAMD will be discussed.

  19. Radionuclide Emission Estimation for the Center for Advanced Energy Studies (CAES)

    SciTech Connect

    Bradley J Schrader

    2010-02-01

    An Radiological Safety Analysis Computer Program (RSAC)-7 model dose assessment was performed to evaluate maximum Center for Advanced Energy Studies (CAES) boundary effective dose equivalent (EDE, in mrem/yr) for potential individual releases of radionuclides from the facility. The CAES is a public/private partnership between the State of Idaho and its academic research institutions, the federal government through the U.S. Department of Energy (DOE), and the Idaho National Laboratory (INL) managed by the Battelle Energy Alliance (BEA). CAES serves to advance energy security for our nation by expanding educational opportunities at Idaho universities in energy-related areas, creating new capabilities within its member institutions, and delivering technological innovations leading to technology-based economic development for the intermountain region. CAES has developed a strategic plan (INL/EXT-07-12950) based on the balanced scorecard approach. At the present time it is unknown exactly what processes will be used in the facility in support of this strategic plan. What is known is that the Idaho State University (ISU) Radioactive Materials License (Nuclear Regulatory Commission [NRC] license 11-27380-01) is the basis for handling radioactive material in the facility. The material in this license is shared between the ISU campus and the CAES facility. There currently are no agreements in place to limit the amount of radioactive material at the CAES facility or what is done to the material in the facility. The scope of this analysis is a summary look at the basis dose for each radionuclide included under the license at a distance of 100, 500, and 1,000 m. Inhalation, ingestion and ground surface dose was evaluated using the NRC design basis guidelines. The results can be used to determine a sum of the fractions approach to facility safety. This sum of the fractions allows a facility threshold value (TV) to be established and potential activities to be evaluated against

  20. Advanced Stirling Convertor (ASC-E2) Performance Testing at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Oriti, Salvatore; Wilson, Scott

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) has been supporting development of the Advanced Stirling Radioisotope Generator (ASRG) since 2006. A key element of the ASRG Project is providing life, reliability, and performance testing of the Advanced Stirling Convertor (ASC). For this purpose, four pairs of ASCs capable of operating to 850 C and designated with the model number ASC-E2, were delivered by Sunpower of Athens, Ohio, to GRC in 2010. The ASC-E2s underwent a series of tests that included workmanship vibration testing, performance mapping, and extended operation. Workmanship vibration testing was performed following fabrication of each convertor to verify proper hardware build. Performance mapping consisted of operating each convertor at various conditions representing the range expected during a mission. Included were conditions representing beginning-of-mission (BOM), end-of-mission (EOM), and fueling. This same series of tests was performed by Sunpower prior to ASC-E2 delivery. The data generated during the GRC test were compared to performance before delivery. Extended operation consisted of a 500-hr period of operation with conditions maintained at the BOM point. This was performed to demonstrate steady convertor performance following performance mapping. Following this initial 500-hr period, the ASC-E2s will continue extended operation, controller development and special durability testing, during which the goal is to accumulate tens of thousands of hours of operation. Data collected during extended operation will support reliability analysis. Performance data from these tests is summarized in this paper.

  1. Advanced Stirling Convertor (ASC-E2) Performance Testing at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Oriti, Salvatore; Wilson, Scott

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) has been supporting development of the Advanced Stirling Radioisotope Generator (ASRG) since 2006. A key element of the ASRG Project is providing life, reliability, and performance testing of the Advanced Stirling Convertor (ASC). For this purpose, four pairs of ASCs capable of operating to 850 C and designated with the model number ASC-E2, were delivered by Sunpower of Athens, OH, to GRC in 2010. The ASC-E2s underwent a series of tests that included workmanship vibration testing, performance mapping, and extended operation. Workmanship vibration testing was performed following fabrication of each convertor to verify proper hardware build. Performance mapping consisted of operating each convertor at various conditions representing the range expected during a mission. Included were conditions representing beginning-of-mission (BOM), end-of-mission (EOM), and fueling. This same series of tests was performed by Sunpower prior to ASC-E2 delivery. The data generated during the GRC test were compared to performance before delivery. Extended operation consisted of a 500-hour period of operation with conditions maintained at the BOM point. This was performed to demonstrate steady convertor performance following performance mapping. Following this initial 500-hour period, the ASC-E2s will continue extended operation, controller development and special durability testing, during which the goal is to accumulate tens of thousands of hours of operation. Data collected during extended operation will support reliability analysis. Performance data from these tests is summarized in this paper.

  2. Improved Methods for the Clinical Manufacture of Proteins Used In Cancer Immunotherapy | NCI Technology Transfer Center | TTC

    Cancer.gov

    Interleukin-15 (IL-15) is an immune system modulating protein (cytokine) that stimulates the proliferation and differentiation of T- lymphocytes.  In the clinical context, IL-15 is being investigated for use in the treatment of diseases such as cancer.  Manufacture of IL-15 for clinical use can be problematic. The National Cancer Institute seeks partners to co-develop or license methods that facilitate pharmaceutical purification and processing of Interleukin-15 (IL-15).

  3. Advanced Study Center: Proceedings of the National Faculty Plenary Conference (Columbus, Ohio, October 30-November 1, 1978).

    ERIC Educational Resources Information Center

    Jackson, Elise B., Ed.; Russell, Earl B., Ed.

    These proceedings contain presentations made at the National Faculty Plenary Conference, whose theme, Nurturing Vocational Education's Leadership and Intellectual Capital, involved these topics: planning, evaluation, recruitment, and policy implications as they relate to the development and implementation of an Advanced Study Center. Introductory…

  4. 75 FR 69468 - Dentek.com, D/B/A Nsequence Center for Advanced Dentistry; Reno, NV; Notice of Affirmative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... Employment and Training Administration Dentek.com , D/B/A Nsequence Center for Advanced Dentistry; Reno, NV... engaged in employment related to the production of dental prosthetics. The initial determination was based... directly competitive with dental prosthetics or a shift/acquisition of these articles to a foreign...

  5. Realizing the potential of the CUAHSI Water Data Center to advance Earth Science

    NASA Astrophysics Data System (ADS)

    Hooper, R. P.; Seul, M.; Pollak, J.; Couch, A.

    2015-12-01

    The CUAHSI Water Data Center has developed a cloud-based system for data publication, discovery and access. Key features of this system are a semantically enabled catalog to discover data across more than 100 different services and delivery of data and metadata in a standard format. While this represents a significant technical achievement, the purpose of this system is to support data reanalysis for advancing science. A new web-based client, HydroClient, improves access to the data from previous clients. This client is envisioned as the first step in a workflow that can involve visualization and analysis using web-processing services, followed by download to local computers for further analysis. The release of the WaterML library in the R package CRAN repository is an initial attempt at linking the WDC services in a larger analysis workflow. We are seeking community input on other resources required to make the WDC services more valuable in scientific research and education.

  6. Solving the Big Data (BD) Problem in Advanced Manufacturing (Subcategory for work done at Georgia Tech. Study Process and Design Factors for Additive Manufacturing Improvement)

    SciTech Connect

    Clark, Brett W.; Diaz, Kimberly A.; Ochiobi, Chinaza Darlene; Paynabar, Kamran

    2015-09-01

    3D printing originally known as additive manufacturing is a process of making 3 dimensional solid objects from a CAD file. This ground breaking technology is widely used for industrial and biomedical purposes such as building objects, tools, body parts and cosmetics. An important benefit of 3D printing is the cost reduction and manufacturing flexibility; complex parts are built at the fraction of the price. However, layer by layer printing of complex shapes adds error due to the surface roughness. Any such error results in poor quality products with inaccurate dimensions. The main purpose of this research is to measure the amount of printing errors for parts with different geometric shapes and to analyze them for finding optimal printing settings to minimize the error. We use a Design of Experiments framework, and focus on studying parts with cone and ellipsoid shapes. We found that the orientation and the shape of geometric shapes have significant effect on the printing error. From our analysis, we also determined the optimal orientation that gives the least printing error.

  7. White paper: A plan for cooperation between NASA and DARPA to establish a center for advanced architectures

    NASA Technical Reports Server (NTRS)

    Denning, P. J.; Adams, G. B., III; Brown, R. L.; Kanerva, P.; Leiner, B. M.; Raugh, M. R.

    1986-01-01

    Large, complex computer systems require many years of development. It is recognized that large scale systems are unlikely to be delivered in useful condition unless users are intimately involved throughout the design process. A mechanism is described that will involve users in the design of advanced computing systems and will accelerate the insertion of new systems into scientific research. This mechanism is embodied in a facility called the Center for Advanced Architectures (CAA). CAA would be a division of RIACS (Research Institute for Advanced Computer Science) and would receive its technical direction from a Scientific Advisory Board established by RIACS. The CAA described here is a possible implementation of a center envisaged in a proposed cooperation between NASA and DARPA.

  8. A microtomography beamline at the Louisiana State University Center for Advanced Microstructures and Devices synchrotron

    NASA Astrophysics Data System (ADS)

    Ham, Kyungmin; Jin, Hua; Butler, Leslie G.; Kurtz, Richard L.

    2002-03-01

    A microtomography beamline has been recently assembled and is currently operating at the Louisiana State University's Center for Advanced Microstructures and Devices synchrotron (CAMD). It has been installed on a bending magnet white-light beamline at port 7A. With the storage ring operating at 1.5 GeV, this beamline has a maximum usable x-ray energy of ˜15 keV. The instrumentation consists of computer-controlled positioning stages for alignment and rotation, a CsI(Tl) phosphor screen, a reflecting mirror, a microscope objective (1:1, 1:4), and Linux/LabVIEW-controlled charge coupled device. With the 1:4 objective, the maximum spatial resolution is 2.25 μm. The positioning and image acquisition computers communicate via transfer control protocol/internet protocol (TCP/IP). A small G4/Linux cluster has been installed for the purpose of on-site reconstruction. Instrument, alignment and reconstruction programs are written in MATLAB, IDL, and C. The applications to date are many and we present several examples. Several biological samples have been studied as part of an effort on biological visualization and computation. Future improvements to this microtomography station include the addition of a double-multilayer monochromator, allowing one to evaluate the three-dimensional elemental composition of materials. Plans also include eventual installation at the CAMD 7 T wiggler beamline, providing x rays in excess of 50 keV to provide better penetration of higher mass-density materials.

  9. Advances in surveillance of periodontitis: the Centers for Disease Control and Prevention periodontal disease surveillance project.

    PubMed

    Eke, Paul I; Thornton-Evans, Gina; Dye, Bruce; Genco, Robert

    2012-11-01

    The Centers for Disease Control and Prevention (CDC) has as one of its strategic goals to support and improve surveillance of periodontal disease. In 2003, the CDC initiated the CDC Periodontal Disease Surveillance Project in collaboration with the American Academy of Periodontology to address population-based surveillance of periodontal disease at the local, state, and national levels. This initiative has made significant advancements toward the goal of improved surveillance, including developing valid self-reported measures that can be obtained from interview-based surveys to predict prevalence of periodontitis in populations. This will allow surveillance of periodontitis at the state and local levels and in countries where clinical resources for surveillance are scarce. This work has produced standard case definitions for surveillance of periodontitis that are now widely recognized and applied in population studies and research. At the national level, this initiative has evaluated the validity of previous clinical examination protocols and tested new protocols on the National Health and Nutrition Examination Survey (NHANES), recommending and supporting funding for the gold-standard full-mouth periodontal examination in NHANES 2009 to 2012. These examinations will generate accurate estimates of the prevalence of periodontitis in the US adult population and provide a superior dataset for surveillance and research. Also, this data will be used to generate the necessary coefficients for our self-report questions for use in subsets of the total US population. The impact of these findings on population-based surveillance of periodontitis and future directions of the project are discussed along with plans for dissemination and translation efforts for broader public health use.

  10. Advancing the Culture of Teaching on Campus: How a Teaching Center Can Make a Difference

    ERIC Educational Resources Information Center

    Cook, Constance, Ed.; Kaplan, Matthew, Ed.

    2011-01-01

    Written by the director and staff of the first, and one of the largest, teaching centers in American higher education--the University of Michigan's Center for Research on Learning and Teaching (CRLT)--this book offers a unique perspective on the strategies for making a teaching center integral to an institution's educational mission. It presents a…

  11. Performance of advanced air bags based on data William Lehman Injury Research Center and new NASS PSUs.

    PubMed

    Augenstein, Jeffrey; Digges, Kennerly

    2003-01-01

    The Ryder Trauma Center is a Level I trauma center that treats only the most severely injured occupants of vehicle crashes as well as other severe cases of trauma. The center investigates these crashes through funding provided by the Alliance of Automobile Manufacturers and the U.S. Department of Transportation-sponsored Crash Injury Research and Engineering Network (CIREN) program. MAIS 3+ nonfatal and fatal injuries comprise approximately 2 percent of the total NASS/CDS cases. Among the Ryder trauma center cases, 50 percent are MAIS 3+ and 25 percent are fatal. If the MAIS 3+ fatal and nonfatal injuries were considered as "failures" and the remaining 98 percent with MAIS 2 or less as successes, this could be equated to the 75 percent failure rate (MAIS 3+ and fatal) in the trauma center cases for analysis purposes. The total database of frontal cases with no rollover consists of 147 drivers with first-generation airbags and 58 cases with second-generation airbags.

  12. Ultrahigh head pump/turbine development program: Volume 4, Advanced design: Strength manufacturability, controls, and reliability: Final report

    SciTech Connect

    Yokoyama, T.

    1987-01-01

    The commercial availability of an ultrahigh head pump/turbine whose output can be regulated makes underground and ultrahigh head-pumped storage creditable options for utility use by reducing construction costs and plant complexity. This new turbine operates at double the head of existing equipment yet uses commercial materials, proven design concepts, and manageable manufacturing techniques. This volume discusses the stress analysis and fatigue evaluation, manufacturability, control system, and reliability and maintainability analyses.

  13. Manufacturing technology

    SciTech Connect

    Leonard, J.A.; Floyd, H.L.; Goetsch, B.; Doran, L.

    1993-08-01

    This bulletin depicts current research on manufacturing technology at Sandia laboratories. An automated, adaptive process removes grit overspray from jet engine turbine blades. Advanced electronic ceramics are chemically prepared from solution for use in high- voltage varistors. Selective laser sintering automates wax casting pattern fabrication. Numerical modeling improves performance of photoresist stripper (simulation on Cray supercomputer reveals path to uniform plasma). And mathematical models help make dream of low- cost ceramic composites come true.

  14. 75 FR 71463 - Dentek.Com, Inc. D/B/A Nsequence Center for Advanced Dentistry Reno, NV; Notice of Negative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Employment and Training Administration Dentek.Com, Inc. D/B/A Nsequence Center for Advanced Dentistry Reno... production of dental prosthetics (such as crowns and the bridges). Pursuant to 29 CFR 90.18(c... workers at Dentek.com , Inc., d/b/a nSequence Center for Advanced Dentistry, Reno, Nevada (the...

  15. Simulation of changes in heavy metal contamination in farmland soils of a typical manufacturing center through logistic-based cellular automata modeling.

    PubMed

    Qiu, Menglong; Wang, Qi; Li, Fangbai; Chen, Junjian; Yang, Guoyi; Liu, Liming

    2016-01-01

    A customized logistic-based cellular automata (CA) model was developed to simulate changes in heavy metal contamination (HMC) in farmland soils of Dongguan, a manufacturing center in Southern China, and to discover the relationship between HMC and related explanatory variables (continuous and categorical). The model was calibrated through the simulation and validation of HMC in 2012. Thereafter, the model was implemented for the scenario simulation of development alternatives for HMC in 2022. The HMC in 2002 and 2012 was determined through soil tests and cokriging. Continuous variables were divided into two groups by odds ratios. Positive variables (odds ratios >1) included the Nemerow synthetic pollution index in 2002, linear drainage density, distance from the city center, distance from the railway, slope, and secondary industrial output per unit of land. Negative variables (odds ratios <1) included elevation, distance from the road, distance from the key polluting enterprises, distance from the town center, soil pH, and distance from bodies of water. Categorical variables, including soil type, parent material type, organic content grade, and land use type, also significantly influenced HMC according to Wald statistics. The relative operating characteristic and kappa coefficients were 0.91 and 0.64, respectively, which proved the validity and accuracy of the model. The scenario simulation shows that the government should not only implement stricter environmental regulation but also strengthen the remediation of the current polluted area to effectively mitigate HMC.

  16. A synopsis of the Defense Advanced Research Projects Agency (DARPA) investment in additive manufacture and what challenges remain

    NASA Astrophysics Data System (ADS)

    Maher, Michael; Smith, Adrien; Margiotta, Jesse

    2014-03-01

    DARPA's interest in additive manufacture dates back to the mid-80s with seedling programs that developed the foundational knowledge and equipment that led to the Solid Freeform Fabrication program in 1990. The drivers for this program included reducing development times by enabling "tool-less" manufacturing as well as integration of design and fabrication tools. DARPA consistently pushed the boundaries of additive manufacture with follow-on programs that expanded the material suite available for 3-D printing as well as new processes that expanded the technology's capability base. Programs such as the Mesoscopic Integrated Conformal Electronics (MICE) program incorporated functionality to the manufacturing processes through direct write of electronics. DARPA's investment in additive manufacture continues to this day but the focus has changed. DARPA's early investments were focused on developing and demonstrating the technology's capabilities. Now that the technology has been demonstrated, there is serious interest in taking advantage of the attributes unique to the processing methodology (such as customization and new design possibilities) for producing production parts. Accordingly, today's investment at DARPA addresses the systematic barriers to implementation rather than the technology itself. The Open Manufacturing program is enabling rapid qualification of new technologies for the manufacturing environment through the development of new modeling and informatics tools. While the technology is becoming more mainstream, there are plenty of challenges that need to be addressed. And as the technology continues to mature, the agency will continue to look for those "DARPA-hard" challenges that enable revolutionary changes in capability and performance for the Department of Defense.

  17. Earth resources programs at the Langley Research Center. Part 1: Advanced Applications Flight Experiments (AAFE) and microwave remote sensing program

    NASA Technical Reports Server (NTRS)

    Parker, R. N.

    1972-01-01

    The earth resources activity is comprised of two basic programs as follows: advanced applications flight experiments, and microwave remote sensing. The two programs are in various stages of implementation, extending from experimental investigations within both the AAFE program and the microwave remote sensing program, to multidisciplinary studies and planning. The purpose of this paper is simply to identify the main thrust of the Langley Research Center activity in earth resources.

  18. Applying Additive Manufacturing to a New Liquid Oxygen Turbopump Design

    NASA Technical Reports Server (NTRS)

    O’Neal, T. Derek

    2016-01-01

    A liquid oxygen turbopump has been designed at Marshall Space Flight Center as part of the in-house, Advanced Manufacturing Demonstrator Engine (AMDE) project. Additive manufacturing, specifically direct metal laser sintering (DMLS) of Inconel 718, is used for 77% of the parts by mass. These parts include the impeller, turbine components, and housings. This paper discusses the impacts of the DMLS fabrication technique on the design of the turbopump and lessons learned during DMLS hardware fabrication and material testing.

  19. CNC Turning Center Advanced Operations. Computer Numerical Control Operator/Programmer. 444-332.

    ERIC Educational Resources Information Center

    Skowronski, Steven D.; Tatum, Kenneth

    This student guide provides materials for a course designed to introduce the student to the operations and functions of a two-axis computer numerical control (CNC) turning center. The course consists of seven units. Unit 1 presents course expectations and syllabus, covers safety precautions, and describes the CNC turning center components, CNC…

  20. Advancing Mental Health Research: Washington University's Center for Mental Health Services Research

    ERIC Educational Resources Information Center

    Proctor, Enola K.; McMillen, Curtis; Haywood, Sally; Dore, Peter

    2008-01-01

    Research centers have become a key component of the research infrastructure in schools of social work, including the George Warren Brown School of Social Work at Washington University. In 1993, that school's Center for Mental Health Services Research (CMHSR) received funding from the National Institute of Mental Health (NIMH) as a Social Work…

  1. 78 FR 50069 - National Center for Advancing Translational Sciences; Notice of Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... clearly unwarranted invasion of personal privacy. ] Name of Committee: Cures Acceleration Network Review.... Place: National Institutes of Health, Building 31, Conference Room 6, 31 Center Drive, Bethesda, MD.... Place: National Institutes of Health, Building 31, Conference Room 6, 31 Center Drive, Bethesda,...

  2. A Wish List for the Advancement of University and College Counseling Centers

    ERIC Educational Resources Information Center

    Bishop, John B.

    2016-01-01

    University and college counseling centers continue to meet emerging challenges in higher education. This article addresses three issues: the need for a more unified organizational structure to represent the profession, the potential value for counseling centers in seeking accreditation, and the importance of specialized training for those entering…

  3. Teaching Advanced Skills to Educationally Disadvantaged Students. Data Analysis Support Center (DASC) Task 4. Final Report.

    ERIC Educational Resources Information Center

    Means, Barbara, Ed.; Knapp, Michael S., Ed.

    This document comprises six papers that discuss teaching advanced skills to educationally disadvantaged students. An introductory paper, "Models for Teaching Advanced Skills to Educationally Disadvantaged Children" (B. Means and M. S. Knapp), synthesizes the themes that characterize the collection of papers as a whole, and discusses general issues…

  4. Advanced Practice Registered Nurses and Physician Assistants in Sleep Centers and Clinics: A Survey of Current Roles and Educational Background

    PubMed Central

    Colvin, Loretta; Cartwright, Ann; Collop, Nancy; Freedman, Neil; McLeod, Don; Weaver, Terri E.; Rogers, Ann E.

    2014-01-01

    Study Objectives: To survey Advanced Practice Registered Nurse (APRN) and Physician Assistant (PA) utilization, roles and educational background within the field of sleep medicine. Methods: Electronic surveys distributed to American Academy of Sleep Medicine (AASM) member centers and APRNs and PAs working within sleep centers and clinics. Results: Approximately 40% of responding AASM sleep centers reported utilizing APRNs or PAs in predominantly clinical roles. Of the APRNs and PAs surveyed, 95% reported responsibilities in sleep disordered breathing and more than 50% in insomnia and movement disorders. Most APRNs and PAs were prepared at the graduate level (89%), with sleep-specific education primarily through “on the job” training (86%). All APRNs surveyed were Nurse Practitioners (NPs), with approximately double the number of NPs compared to PAs. Conclusions: APRNs and PAs were reported in sleep centers at proportions similar to national estimates of NPs and PAs in physicians' offices. They report predominantly clinical roles, involving common sleep disorders. Given current predictions that the outpatient healthcare structure will change and the number of APRNs and PAs will increase, understanding the role and utilization of these professionals is necessary to plan for the future care of patients with sleep disorders. Surveyed APRNs and PAs reported a significant deficiency in formal and standardized sleep-specific education. Efforts to provide formal and standardized educational opportunities for APRNs and PAs that focus on their clinical roles within sleep centers could help fill a current educational gap. Citation: Colvin L, Cartwright Ann, Collop N, Freedman N, McLeod D, Weaver TE, Rogers AE. Advanced practice registered nurses and physician assistants in sleep centers and clinics: a survey of current roles and educational background. J Clin Sleep Med 2014;10(5):581-587. PMID:24812545

  5. IMPROVEMENT OF WEAR COMPONENT'S PERFORMANCE BY UTILIZING ADVANCED MATERIALS AND NEW MANUFACTURING TECHNOLOGIES: CASTCON PROCESS FOR MINING APPLICATIONS

    SciTech Connect

    Xiaodi Huang; Richard Gertsch

    2003-02-27

    The project was highlighted by continued fabrication of drill bit inserts and testing them: (1) The inserts were subjected to hammer tests to determine brittleness. Selected inserts experienced multiple blows from a 16 pound sledge hammer. The resulting damage was minimal. (2) Three inserts were placed on three different 16.5 inch diameter rotary drill bits, and the bits drilled taconite rock until the entire bit failed. (3) The inserts had somewhat less wear resistance than current art, and exhibited no brittle failures. (4) More work is needed to produce the inserts at near net shape. The test inserts required too much machining. The project next turned to manufacturing 6.5 inch diameter disc cutters. The cutters will feature a core of tungsten carbide (TC) in a disc body composed of H13 tool steel. The TC inserts are in manufacture and the dies for the disc are being designed. The plan for next quarter: (1) Investigate materials and manufacturing changes for the fibrous monolith drill bit inserts that will increase their wear life. (2) Begin manufacturing disc cutters.

  6. Layered Manufacturing: Challenges and Opportunities

    DTIC Science & Technology

    2003-04-01

    UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP014215 TITLE: Layered Manufacturing : Challenges and Opportunities ...Research Society LL1.4 Layered Manufacturing : Challenges and Opportunities Khershed P. Cooper Materials Science and Technology Division, Naval Research...Laboratory Washington, DC 20375-5343, U.S.A. ABSTRACT Layered Manufacturing (LM) refers to computer-aided manufacturing processes in which parts are made

  7. 77 FR 75180 - National Center for Advancing Translational Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Room 6, Bethesda, MD 20892. Contact Person: Danilo A Tagle, Ph.D., Executive Secretary, National Center..., Danilo.Tagle@nih.gov . Any interested person may file written comments with the committee by...

  8. Center for Advancing ystemic Heliophysics Education (CAHEd): Outreach through Community Building

    NASA Astrophysics Data System (ADS)

    Whitman, K.; Kadooka, M.

    2012-12-01

    In 2010, the Center for Advancing ystemic Heliophysics Education (CAHEd) was established at the University of Hawaii Institute for Astronomy to promote public outreach and education of solar astronomy and heliophysics. The primary objectives of CAHEd are to increase public awareness of the significance of heliophysics and space weather through lectures, open houses, and online resources. In addition, CAHEd works to educate secondary teachers and students on physics concepts essential for understanding heliophysics ideas. For the first two years of the NASA sponsored grant, CAHEd has focused its efforts on teachers and students in Hawaii. Approaching its third year, CAHEd has begun to expand to a national level, partnering with teachers in locations across the United States. Two core goals of CAHEd will be discussed here: collaboration with a select group of Master Teachers and student mentoring in research projects. CAHEd has built a partnership with over a dozen Master Teachers that work with scientists to develop curriculum for the middle and high school classroom. These teachers come from diverse backgrounds with a variety of scientific experiences. Master Teachers play the important role of assessing and improving CAHEd curriculum and provide support for CAHEd activities. All Master Teachers participate in in-depth multi-day workshops that allow them to develop a deeper understanding of the science behind heliophysics. After building a strong background, Master Teachers organize workshops, growing a community of teachers who incorporate heliophysics into their curriculum. Scientists also work closely with middle school and high school students who wish to pursue study in heliophysics. Student research is a fundamental goal of CAHEd and scientists work with students to complete projects for school and state science fairs. Four students have completed award winning heliophysics projects to date and three of the four students have gone on to pursue a second

  9. NASA. Lewis Research Center Advanced Modulation and Coding Project: Introduction and overview

    NASA Technical Reports Server (NTRS)

    Budinger, James M.

    1992-01-01

    The Advanced Modulation and Coding Project at LeRC is sponsored by the Office of Space Science and Applications, Communications Division, Code EC, at NASA Headquarters and conducted by the Digital Systems Technology Branch of the Space Electronics Division. Advanced Modulation and Coding is one of three focused technology development projects within the branch's overall Processing and Switching Program. The program consists of industry contracts for developing proof-of-concept (POC) and demonstration model hardware, university grants for analyzing advanced techniques, and in-house integration and testing of performance verification and systems evaluation. The Advanced Modulation and Coding Project is broken into five elements: (1) bandwidth- and power-efficient modems; (2) high-speed codecs; (3) digital modems; (4) multichannel demodulators; and (5) very high-data-rate modems. At least one contract and one grant were awarded for each element.

  10. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    SciTech Connect

    2010-01-01

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  11. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    ScienceCinema

    None

    2016-07-12

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  12. National Energy Research Scientific Computing Center (NERSC): Advancing the frontiers of computational science and technology

    SciTech Connect

    Hules, J.

    1996-11-01

    National Energy Research Scientific Computing Center (NERSC) provides researchers with high-performance computing tools to tackle science`s biggest and most challenging problems. Founded in 1974 by DOE/ER, the Controlled Thermonuclear Research Computer Center was the first unclassified supercomputer center and was the model for those that followed. Over the years the center`s name was changed to the National Magnetic Fusion Energy Computer Center and then to NERSC; it was relocated to LBNL. NERSC, one of the largest unclassified scientific computing resources in the world, is the principal provider of general-purpose computing services to DOE/ER programs: Magnetic Fusion Energy, High Energy and Nuclear Physics, Basic Energy Sciences, Health and Environmental Research, and the Office of Computational and Technology Research. NERSC users are a diverse community located throughout US and in several foreign countries. This brochure describes: the NERSC advantage, its computational resources and services, future technologies, scientific resources, and computational science of scale (interdisciplinary research over a decade or longer; examples: combustion in engines, waste management chemistry, global climate change modeling).

  13. Lens auto-centering

    NASA Astrophysics Data System (ADS)

    Lamontagne, Frédéric; Desnoyers, Nichola; Doucet, Michel; Côté, Patrice; Gauvin, Jonny; Anctil, Geneviève; Tremblay, Mathieu

    2015-09-01

    In a typical optical system, optical elements usually need to be precisely positioned and aligned to perform the correct optical function. This positioning and alignment involves securing the optical element in a holder or mount. Proper centering of an optical element with respect to the holder is a delicate operation that generally requires tight manufacturing tolerances or active alignment, resulting in costly optical assemblies. To optimize optical performance and minimize manufacturing cost, there is a need for a lens mounting method that could relax manufacturing tolerance, reduce assembly time and provide high centering accuracy. This paper presents a patent pending lens mounting method developed at INO that can be compared to the drop-in technique for its simplicity while providing the level of accuracy close to that achievable with techniques using a centering machine (usually < 5 μm). This innovative auto-centering method is based on the use of geometrical relationship between the lens diameter, the lens radius of curvature and the thread angle of the retaining ring. The autocentering principle and centering test results performed on real optical assemblies are presented. In addition to the low assembly time, high centering accuracy, and environmental robustness, the INO auto-centering method has the advantage of relaxing lens and barrel bore diameter tolerances as well as lens wedge tolerances. The use of this novel lens mounting method significantly reduces manufacturing and assembly costs for high performance optical systems. Large volume productions would especially benefit from this advancement in precision lens mounting, potentially providing a drastic cost reduction.

  14. Advanced technology and manufacturing practices for machining and inspecting metal matrix composites. Final CRADA report for CRADA number Y-1292-0092

    SciTech Connect

    Fell, H.A.; Shelton, J.E.; LaMance, G.M.; Kennedy, C.R.

    1995-02-26

    Lockheed Martin Energy Systems, Inc. (Energy Systems) and the Lanxide Corporation (Lanxide) negotiated a Cooperative Research and Development Agreement (CRADA) to develop advanced technology and manufacturing practices for machining and inspecting metal matrix composites (MMC). The objective of this CRADA was to develop machining parameters to allow manufacturing of automotive components from MMCs. These parts exhibit a range of shapes and dimensional tolerances and require a large number of machining operations. The common characteristic of the components is the use of the light weight MMC materials to replace heavier materials. This allows smaller and lighter moving parts and supporting structural components thereby increasing fuel mileage. The CRADA was divided into three areas: basic investigation of cutting parameters, establishment of a mock production line for components, and optimization of parameters in the mock facility. This report covers the manufacturing of MMCs and preliminary Phase I testing for silicon carbide having various loading percentages and extensive Phase I testing of cutting parameters on 30% alumina loaded aluminum. On January 26, 1995, a letter from the vice president, technology at Lanxide was issued terminating the CRADA due to changes in business. 9 refs., 18 figs., 3 tabs.

  15. An Exploratory Analysis for the Selection and Implementation of Advanced Manufacturing Technology by Fuzzy Multi-criteria Decision Making Methods: A Comparative Study

    NASA Astrophysics Data System (ADS)

    Nath, Surajit; Sarkar, Bijan

    2016-06-01

    Advanced Manufacturing Technologies (AMTs) offer opportunities for the manufacturing organizations to excel their competitiveness and in turn their effectiveness in manufacturing. Proper selection and evaluation of AMTs is the most significant task in today's modern world. But this involves a lot of uncertainty and vagueness as it requires many conflicting criteria to deal with. So the task of selection and evaluation of AMTs becomes very tedious for the evaluators as they are not able to provide crisp data for the criteria. Different Fuzzy Multi-criteria Decision Making (MCDM) methods help greatly in dealing with this problem. This paper focuses on the application of two very much potential Fuzzy MCDM methods namely COPRAS-G, EVAMIX and a comparative study between them on some rarely mentioned criteria. Each of the two methods is very powerful evaluation tool and has beauty in its own. Although, performance wise these two methods are almost at same level, but, the approach of each one of them are quite unique. This uniqueness is revealed by introducing a numerical example of selection of AMT.

  16. Ensuring Biologics Advanced Development and Manufacturing Capability for the United States Government: A Summary of Key Findings and Conclusions

    DTIC Science & Technology

    2009-10-06

    development time for the facility;  No animal-derived products will be manufactured (e.g., equine hyper-immune globulin, transgenic animals);  Although...spectrum‖ products that would provide protection against a variety of threats. The example of antibiotics is cited as a model for how these broad...3,600,000 24,000,000 300,000 4,800,000 Eastern Equine Encephalitis (EEE) Vaccine 5,200,000

  17. The National Center for Biomedical Ontology: Advancing Biomedicinethrough Structured Organization of Scientific Knowledge

    SciTech Connect

    Rubin, Daniel L.; Lewis, Suzanna E.; Mungall, Chris J.; Misra,Sima; Westerfield, Monte; Ashburner, Michael; Sim, Ida; Chute,Christopher G.; Solbrig, Harold; Storey, Margaret-Anne; Smith, Barry; Day-Richter, John; Noy, Natalya F.; Musen, Mark A.

    2006-01-23

    The National Center for Biomedical Ontology (http://bioontology.org) is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists funded by the NIH Roadmap to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are: (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. The Center is working toward these objectives by providing tools to develop ontologies and to annotate experimental data, and by developing resources to integrate and relate existing ontologies as well as by creating repositories of biomedical data that are annotated using those ontologies. The Center is providing training workshops in ontology design, development, and usage, and is also pursuing research in ontology evaluation, quality, and use of ontologies to promote scientific discovery. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease.

  18. Manufacturing technology

    NASA Astrophysics Data System (ADS)

    Leonard, J. A.; Floyd, H. L.; Goetsch, B.; Doran, L.

    1993-08-01

    This bulletin depicts current research on manufacturing technology at Sandia laboratories. An automated, adaptive process removes grit overspray from jet engine turbine blades. Advanced electronic ceramics are chemically prepared from solution for use in high-voltage varistors. A selective laser sintering process automates wax casting pattern fabrication. Numerical modeling improves the performance of a photoresist stripper (a simulation on a Cray supercomputer reveals the path of a uniform plasma). Improved mathematical models will help make the dream of low-cost ceramic composites come true.

  19. Fuel Properties Database from the Alternative Fuels and Advanced Vehicles Data Center (AFDC)

    DOE Data Explorer

    This database contains information on advanced petroleum and non-petroleum based fuels, as well as key data on advanced compression ignition fuels. Included are data on physical, chemical, operational, environmental, safety, and health properties. These data result from tests conducted according to standard methods (mostly American Society for Testing and Materials (ASTM). The source and test methods for each fuel data set are provided with the information. The database can be searched in various ways and can output numbers or explanatory text. Heavy vehicle chassis emission data are also available for some fuels.

  20. The Emory Chemical Biology Discovery Center: leveraging academic innovation to advance novel targets through HTS and beyond.

    PubMed

    Johns, Margaret A; Meyerkord-Belton, Cheryl L; Du, Yuhong; Fu, Haian

    2014-03-01

    The Emory Chemical Biology Discovery Center (ECBDC) aims to accelerate high throughput biology and translation of biomedical research discoveries into therapeutic targets and future medicines by providing high throughput research platforms to scientific collaborators worldwide. ECBDC research is focused at the interface of chemistry and biology, seeking to fundamentally advance understanding of disease-related biology with its HTS/HCS platforms and chemical tools, ultimately supporting drug discovery. Established HTS/HCS capabilities, university setting, and expertise in diverse assay formats, including protein-protein interaction interrogation, have enabled the ECBDC to contribute to national chemical biology efforts, empower translational research, and serve as a training ground for young scientists. With these resources, the ECBDC is poised to leverage academic innovation to advance biology and therapeutic discovery.

  1. The National Palliative Care Research Center and the Center to Advance Palliative Care: a partnership to improve care for persons with serious illness and their families.

    PubMed

    Morrison, R Sean; Meier, Diane E

    2011-10-01

    families must know to request palliative care, medical professionals must have the knowledge and skills to provide palliative care, and hospitals and other healthcare institutions must be equipped to deliver and support palliative care services. The Center to Advance Palliative Care (CAPC) and the National Palliative Care Research Center (NPCRC) are accomplishing this three-part mission by working in partnership to: 1) Develop research to serve as the knowledge base for quality clinical care and the foundation on which to build palliative care programs and systems; 2) Disseminate this knowledge to patients, families, professionals, and institutions throughout the United States and ensure that it is integrated within mainstream healthcare; and 3) Influence and collaborate with policy makers , regulatory bodies, and federal funding agencies to ensure that the healthcare infrastructure supports the continued growth and development of palliative care.

  2. Recent Efforts in Advanced High Frequency Communications at the Glenn Research Center in Support of NASA Mission

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2015-01-01

    This presentation will discuss research and technology development work at the NASA Glenn Research Center in advanced frequency communications in support of NASAs mission. An overview of the work conducted in-house and also in collaboration with academia, industry, and other government agencies (OGA) in areas such as antenna technology, power amplifiers, radio frequency (RF) wave propagation through Earths atmosphere, ultra-sensitive receivers, among others, will be presented. In addition, the role of these and other related RF technologies in enabling the NASA next generation space communications architecture will be also discussed.

  3. Learner-Centered Strategies and Advanced Mathematics: A Study of Students' Perspectives

    ERIC Educational Resources Information Center

    Ortiz-Robinson, Norma L.; Ellington, Aimee J.

    2009-01-01

    A number of learner-centered strategies were implemented during a two-semester course in real analysis that is traditionally taught in lecture format. We seek to understand the role that these strategies can have in this proof-intensive theoretical mathematics classroom and the perceived benefits by the students. Although learner-centered…

  4. 77 FR 74674 - National Center for Advancing Translational Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    .... App.), notice is hereby given of a meeting of the Cures Acceleration Network Review Board. The meeting... Acceleration Network Review Board. Date: January 23, 2013. Time: 8:30 a.m. to 2:45 p.m. Agenda: Report of the Institute Director. Place: National Institutes of Health, Building 31, Conference Room 6, 31 Center...

  5. Aluminum-centered tetrahedron-octahedron transition in advancing Al-Sb-Te phase change properties.

    PubMed

    Xia, Mengjiao; Ding, Keyuan; Rao, Feng; Li, Xianbin; Wu, Liangcai; Song, Zhitang

    2015-02-24

    Group IIIA elements, Al, Ga, or In, etc., doped Sb-Te materials have proven good phase change properties, especially the superior data retention ability over popular Ge2Sb2Te5, while their phase transition mechanisms are rarely investigated. In this paper, aiming at the phase transition of Al-Sb-Te materials, we reveal a dominant rule of local structure changes around the Al atoms based on ab initio simulations and nuclear magnetic resonance evidences. By comparing the local chemical environments around Al atoms in respective amorphous and crystalline Al-Sb-Te phases, we believe that Al-centered motifs undergo reversible tetrahedron-octahedron reconfigurations in phase transition process. Such Al-centered local structure rearrangements significantly enhance thermal stability of amorphous phase compared to that of undoped Sb-Te materials, and facilitate a low-energy amorphization due to the weak links among Al-centered and Sb-centered octahedrons. Our studies may provide a useful reference to further understand the underlying physics and optimize performances of all IIIA metal doped Sb-Te phase change materials, prompting the development of NOR/NAND Flash-like phase change memory technology.

  6. The USGS National Wildlife Health Center: Advancing wildlife and ecosystem health

    USGS Publications Warehouse

    Moede Rogall, Gail; Sleeman, Jonathan M.

    2017-01-11

    In 1975, the Federal government responded to the need for establishing national expertise in wildlife health by creating the National Wildlife Health Center (NWHC), a facility within the Department of the Interior; the NWHC is the only national center dedicated to wildlife disease detection, control, and prevention. Its mission is to provide national leadership to safeguard wildlife and ecosystem health through active partnerships and exceptional science. Comparisons are often made between the NWHC, which strives to protect the health of our Nation’s wildlife, and the Centers for Disease Control and Prevention (CDC), which strive to protect public health. The NWHC, a science center of the U.S. Geological Survey (USGS) with specialized laboratories, works to safeguard the Nation’s wildlife from diseases by studying the causes and drivers of these threats, and by developing strategies to prevent and manage them. In addition to the main campus, located in Madison, Wisconsin, the NWHC also operates the Honolulu Field Station that addresses wildlife health issues in Hawaii and the Pacific Region.

  7. CALS Tech Bulletin #3. An Occasional Publication of the Center for Advanced Learning Systems.

    ERIC Educational Resources Information Center

    CSR, Inc., Washington, DC.

    This paper contains brief synopses of recent technical progress/projects in the field of advanced learning systems. This issue contains the following 12 items: (1) "Guest Editorial" (Sylvia Charp) concerning the need to provide better learning experiences for all students; (2) "Steps in Developing an Expert Systems Model," as…

  8. Applying Additive Manufacturing to a New Liquid Oxygen Turbopump Design

    NASA Technical Reports Server (NTRS)

    O'Neal, Derek

    2016-01-01

    A liquid oxygen turbopump has been designed at Marshall Space Flight Center as part of the in-house, Advanced Manufacturing Demonstrator Engine (AMDE) project. Additive manufacturing, specifically direct metal laser sintering (DMLS) of Inconel 718, is used for 77% of the parts by mass. These parts include the impeller, turbine components, and housings. The near-net shape DMLS parts have been delivered and final machining is underway. Fabrication of the traditionally manufactured hardware is also proceeding. Testing in liquid oxygen is planned for Q2 of FY2017. This topic explores the design of the turbopump along with fabrication and material testing of the DMLS hardware.

  9. Green Manufacturing

    SciTech Connect

    Patten, John

    2013-12-31

    Green Manufacturing Initiative (GMI): The initiative provides a conduit between the university and industry to facilitate cooperative research programs of mutual interest to support green (sustainable) goals and efforts. In addition to the operational savings that greener practices can bring, emerging market demands and governmental regulations are making the move to sustainable manufacturing a necessity for success. The funding supports collaborative activities among universities such as the University of Michigan, Michigan State University and Purdue University and among 40 companies to enhance economic and workforce development and provide the potential of technology transfer. WMU participants in the GMI activities included 20 faculty, over 25 students and many staff from across the College of Engineering and Applied Sciences; the College of Arts and Sciences' departments of Chemistry, Physics, Biology and Geology; the College of Business; the Environmental Research Institute; and the Environmental Studies Program. Many outside organizations also contribute to the GMI's success, including Southwest Michigan First; The Right Place of Grand Rapids, MI; Michigan Department of Environmental Quality; the Michigan Department of Energy, Labor and Economic Growth; and the Michigan Manufacturers Technical Center.

  10. Computers in Manufacturing.

    ERIC Educational Resources Information Center

    Hudson, C. A.

    1982-01-01

    Advances in factory computerization (computer-aided design and computer-aided manufacturing) are reviewed, including discussions of robotics, human factors engineering, and the sociological impact of automation. (JN)

  11. Development of Advanced Computational Aeroelasticity Tools at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Bartels, R. E.

    2008-01-01

    NASA Langley Research Center has continued to develop its long standing computational tools to address new challenges in aircraft and launch vehicle design. This paper discusses the application and development of those computational aeroelastic tools. Four topic areas will be discussed: 1) Modeling structural and flow field nonlinearities; 2) Integrated and modular approaches to nonlinear multidisciplinary analysis; 3) Simulating flight dynamics of flexible vehicles; and 4) Applications that support both aeronautics and space exploration.

  12. Advanced manufacturing development of a composite empennage component for L-1011 aircraft. Phase 4: Full scale ground test

    NASA Technical Reports Server (NTRS)

    Jackson, A. C.; Dorwald, F.

    1982-01-01

    The ground tests conducted on the advanced composite vertical fin (ACVF) program are described. The design and fabrication of the test fixture and the transition structure, static test of Ground Test Article (GTA) No. 1, rework of GTA No. 2, and static, damage tolerance, fail-safe and residual strength tests of GTA No. 2 are described.

  13. IMPROVEMENT OF WEAR COMPONENT'S PERFORMANCE BY UTILIZING ADVANCED MATERIALS AND NEW MANUFACTURING TECHNOLOGIES: CASTCON PROCESS FOR MINING APPLICATIONS

    SciTech Connect

    Xiaodi Huang; Richard Gertsch

    2001-07-27

    A tungsten carbide monolithic preform was produced by Advanced Ceramics. MTU conducted various sintering tests on the preform to determine conditions for removing the organic binder and improving the mechanical properties. The originally selected parameters for sintering did not perform as anticipated and further testing is underway.

  14. Computer Aided Manufacturing.

    ERIC Educational Resources Information Center

    Insolia, Gerard

    This document contains course outlines in computer-aided manufacturing developed for a business-industry technology resource center for firms in eastern Pennsylvania by Northampton Community College. The four units of the course cover the following: (1) introduction to computer-assisted design (CAD)/computer-assisted manufacturing (CAM); (2) CAM…

  15. Clean Energy Manufacturing Initiative

    SciTech Connect

    2013-04-01

    The initiative will strategically focus and rally EERE’s clean energy technology offices and Advanced Manufacturing Office around the urgent competitive opportunity for the United States to be the leader in the clean energy manufacturing industries and jobs of today and tomorrow.

  16. Graduate Automotive Technology Education (GATE) Program: Center of Automotive Technology Excellence in Advanced Hybrid Vehicle Technology at West Virginia University

    SciTech Connect

    Nigle N. Clark

    2006-12-31

    This report summarizes the technical and educational achievements of the Graduate Automotive Technology Education (GATE) Center at West Virginia University (WVU), which was created to emphasize Advanced Hybrid Vehicle Technology. The Center has supported the graduate studies of 17 students in the Department of Mechanical and Aerospace Engineering and the Lane Department of Computer Science and Electrical Engineering. These students have addressed topics such as hybrid modeling, construction of a hybrid sport utility vehicle (in conjunction with the FutureTruck program), a MEMS-based sensor, on-board data acquisition for hybrid design optimization, linear engine design and engine emissions. Courses have been developed in Hybrid Vehicle Design, Mobile Source Powerplants, Advanced Vehicle Propulsion, Power Electronics for Automotive Applications and Sensors for Automotive Applications, and have been responsible for 396 hours of graduate student coursework. The GATE program also enhanced the WVU participation in the U.S. Department of Energy Student Design Competitions, in particular FutureTruck and Challenge X. The GATE support for hybrid vehicle technology enhanced understanding of hybrid vehicle design and testing at WVU and encouraged the development of a research agenda in heavy-duty hybrid vehicles. As a result, WVU has now completed three programs in hybrid transit bus emissions characterization, and WVU faculty are leading the Transportation Research Board effort to define life cycle costs for hybrid transit buses. Research and enrollment records show that approximately 100 graduate students have benefited substantially from the hybrid vehicle GATE program at WVU.

  17. Directory of Manufacturing Research Centers

    DTIC Science & Technology

    1989-06-01

    M. 57 Elias, Luis 55 Hanifin, Leo 46, 136 Elinger, Wayne 105 Harbison-Briggs, Karan 15 Ellingwood, Sara 169 Harnett, Michael 56 Ellis, Edwin 61 Harral...VanKooy, Henry 20 Vicroy, Roger 76 Villanueva, Jose 143 Von Herrman, Pieter 174 Wagner, Harry 26 Wagner, James W. 51 Wakeley, Chris 161 Walk, Robert A...Director of CREOL Dr. Mike Bass, Staff Dr. Glenn Boreman, Staff Dr. Luis Elias, Staff Dr. Karl Gunther, Staff Dr. Dave Hagan, St3ff Dr. Jin Kim, Staff

  18. IMPROVEMENT OF WEAR COMPONENT'S PERFORMANCE BY UTILIZING ADVANCED MATERIALS AND NEW MANUFACTURING TECHNOLOGIES: CASTCON PROCESS FOR MINING APPLICATIONS

    SciTech Connect

    Xiaodi Huang; Richard Gertsch

    2003-05-01

    In this reporting period, the project focused on the investigations of FM material container-less HIPping, disc section examination and heat treatment, and full disc manufacture. The FM container-less HIPping resulted in either full density not being reached or reaching full density but losing the FM structure. Container HIPping seems to be necessary to consolidate the FM material. The heat treatment conducted on the 6.5 inch disc section with a WC insert caused cracking in the WC body and along the WC and H13 boundary. Two full 6.5 inch disc cutters were produced but contained defects. It is planned to produce more full disc cutters in the next quarter.

  19. Advanced Microwave Scanning Radiometer - Earth Observing System (AMSR-E) Validation Data Management at the National Snow and Ice Data Center (NSIDC) Distributed Active Archive Center (DAAC)

    NASA Astrophysics Data System (ADS)

    Marquis, M. C.; Paserba, A. M.

    2003-12-01

    The National Snow and Ice Data Center (NSIDC) Distributed Active Archive Center (DAAC) is supporting the Advanced Microwave Scanning Radiometer - Earth Observing System (AMSR-E) validation activity. NSIDC has designed and developed a web portal to data and information collected during NASA's AMSR-E Validation Program: (http://nsidc.org/data/amsr_validation/.) The AMSR-E validation experiments address three disciplines: soil moisture, rainfall and cryospheric validation campaigns. This poster describes all these experiments (past, present and future). NSIDC provides documentation, e.g., user guides, as well as metadata documents (DIFS) submitted to the Global Change Master Directory (GCMD), for all the AMSR-E validation experiments. NSIDC further supports the validation activities by collaborating with the AMSR-E Science Investigator-led Processing System (SIPS) to provide scientists in the field (e.g., Arctic and Antarctic ship and flight campaigns) with quick, easy access to AMSR-E data for their validation experiments. NSIDC provides subsets of reformatted data in a manner most convenient to the validation scientists while they conduct their experiments. The AMSR-E is a mission instrument launched aboard NASA's Aqua Satellite on 4 May 2002. The Aqua mission provides a multi-disciplinary study of the Earth's atmospheric, oceanic, cryospheric, and land processes and their relationship to global change. With six instruments aboard, the Aqua Satellite will travel in a polar, sun-synchronous orbit. NSIDC will archive and distribute all AMSR-E products, including Levels 1A, 2, and 3 data. Users can order Level-1A AMSR-E data beginning 19 June 2003 and Level-2A data beginning 01 September 2003. Other products will be available in March 2004.

  20. Innovation in Flight: Research of the NASA Langley Research Center on Revolutionary Advanced Concepts for Aeronautics

    NASA Technical Reports Server (NTRS)

    Chambers, Joseph R.

    2005-01-01

    The goal of this publication is to provide an overview of the topic of revolutionary research in aeronautics at Langley, including many examples of research efforts that offer significant potential benefits, but have not yet been applied. The discussion also includes an overview of how innovation and creativity is stimulated within the Center, and a perspective on the future of innovation. The documentation of this topic, especially the scope and experiences of the example research activities covered, is intended to provide background information for future researchers.

  1. Human-centered design of a cyber-physical system for advanced response to Ebola (CARE).

    PubMed

    Dimitrov, Velin; Jagtap, Vinayak; Skorinko, Jeanine; Chernova, Sonia; Gennert, Michael; Padir, Taşkin

    2015-01-01

    We describe the process towards the design of a safe, reliable, and intuitive emergency treatment unit to facilitate a higher degree of safety and situational awareness for medical staff, leading to an increased level of patient care during an epidemic outbreak in an unprepared, underdeveloped, or disaster stricken area. We start with a human-centered design process to understand the design challenge of working with Ebola treatment units in Western Africa in the latest Ebola outbreak, and show preliminary work towards cyber-physical technologies applicable to potentially helping during the next outbreak.

  2. NASA Center for Climate Simulation (NCCS) Advanced Technology AT5 Virtualized Infiniband Report

    NASA Technical Reports Server (NTRS)

    Thompson, John H.; Bledsoe, Benjamin C.; Wagner, Mark; Shakshober, John; Fromkin, Russ

    2013-01-01

    The NCCS is part of the Computational and Information Sciences and Technology Office (CISTO) of Goddard Space Flight Center's (GSFC) Sciences and Exploration Directorate. The NCCS's mission is to enable scientists to increase their understanding of the Earth, the solar system, and the universe by supplying state-of-the-art high performance computing (HPC) solutions. To accomplish this mission, the NCCS (https://www.nccs.nasa.gov) provides high performance compute engines, mass storage, and network solutions to meet the specialized needs of the Earth and space science user communities

  3. DOD Initiatives to Rapidly Transition Advanced Coating and Surface Finishing Technologies for Military Turbine Engine Manufacture and Repair

    DTIC Science & Technology

    2005-03-21

    of PEWG Projects Involving Plating, Coating, and Surface Finishing • Advanced thermal spray coatings (HVOF) • Electrospark deposition • Laser...EWI, GEAE, P&W, Rolls-Royce FUNDING SOURCES RTOC STATUS OC-ALC request for FY06 Funding 3/21/2005 22 Other Technologies • Electrospark Deposition for...Aircraft Engines PEWG MANAGER Chuck Alford, Anteon Corp TECHNOLOGY OPPORTUNITY ADVANTAGES: Kinetic spray technologies deposit thick coatings with a

  4. Meaning-Centered Group Psychotherapy: An Effective Intervention for Improving Psychological Well-Being in Patients With Advanced Cancer

    PubMed Central

    Breitbart, William; Rosenfeld, Barry; Pessin, Hayley; Applebaum, Allison; Kulikowski, Julia; Lichtenthal, Wendy G.

    2015-01-01

    Purpose To test the efficacy of meaning-centered group psychotherapy (MCGP) to reduce psychological distress and improve spiritual well-being in patients with advanced or terminal cancer. Patients and Methods Patients with advanced cancer (N = 253) were randomly assigned to manualized eight-session interventions of either MCGP or supportive group psychotherapy (SGP). Patients were assessed before and after completing the treatment and 2 months after treatment. The primary outcome measures were spiritual well-being and overall quality of life, with secondary outcome measures assessing depression, hopelessness, desire for hastened death, anxiety, and physical symptom distress. Results Hierarchical linear models that included a priori covariates and only participants who attended ≥ three sessions indicated a significant group × time interaction for most outcome variables. Specifically, patients receiving MCGP showed significantly greater improvement in spiritual well-being and quality of life and significantly greater reductions in depression, hopelessness, desire for hastened death, and physical symptom distress compared with those receiving SGP. No group differences were observed for changes in anxiety. Analyses that included all patients, regardless of whether they attended any treatment sessions (ie, intent-to-treat analyses), and no covariates still showed significant treatment effects (ie, greater benefit for patients receiving MCGP v SGP) for quality of life, depression, and hopelessness but not for other outcome variables. Conclusion This large randomized controlled study provides strong support for the efficacy of MCGP as a treatment for psychological and existential or spiritual distress in patients with advanced cancer. PMID:25646186

  5. Advanced manufacturing technologies for reduced cost and weight in portable ruggedized VIS-IR and multi-mode optical systems for land, sea, and air

    NASA Astrophysics Data System (ADS)

    Sweeney, Michael; Spinazzola, Robert; Morrison, Donald; Macklin, Dennis; Marion, Jared

    2011-06-01

    Homeland security systems, special forces, unmanned aerial vehicles (UAV), and marine patrols require low cost, high performance, multi-mode visible through infrared (VIS-IR) wavelength optical systems to identify and neutralize potential threats that often arise at long ranges and under poor visibility conditions. Long range and wide spectral performance requirements favor reflective optical system design solutions. The limited field of view of such designs can be significantly enhanced by the use of catadioptric optical solutions that utilize molded or diamond point machined VIS-IR lenses downstream from reflective objective optics. A common optical aperture that services multiple modes of field-of-view, operating wavelength, and includes laser ranging and spotting, provides the highest utility and is most ideal for size and weight. Such a design also often requires fast, highly aspheric, reflective, refractive, and sometimes diffractive surfaces using high performance and aggressively light-weighted materials that demand the finest of manufacturing technologies. Visible wavelength performance sets the bar for component optical surface irregularity on the order of 20 nm RMS and surface finishes less than 3.0 nm RMS. Aluminum mirrors and structures can also be precision machined to yield "snap together alignment" or limited compensation assembly approaches to reduce cost and enhance interchangeability. Diamond point turning, die cast and investment cast mirror substrates and structures, computerized optical polishing, mirror replication, lens molding and other advanced manufacturing technologies can all be used to minimize the cost of this type of optical equipment. This paper discusses the tradeoffs among materials and process selection for catadioptric, multi-mode systems that are under development for a variety of DoD and Homeland Security applications. Several examples are profiled to illuminate the confluence of applicable design and manufacturing

  6. An overview of the demonstration advanced avionics system guest pilot evaluation conducted at Ames Research Center

    NASA Technical Reports Server (NTRS)

    Callas, G. P.; Hardy, G. H.; Denery, D. G.

    1983-01-01

    The guest pilot flight evaluation of the Demonstration Advanced Avionics System (DAAS) is discussed. The results are based on the fifty-nine questionnaires that were completed by the participants. The primary purpose of the pilot evaluation was to expose the Demonstration Advanced Avionics System to the various segments of the general aviation community and solicit comments in order to determine the effectiveness of integrated avionics for general aviation. Segments of the community that were represented in the evaluation are listed. A total of sixty-four (64) flights were conducted in which one hundred and seventeen (117) pilots and observers participated. It was felt that the exposure each subject had with the DAAS was too short to adequately assess the training requirements, pilot workload, and the reconfiguration concept of the DAAS. It is recommended that an operational evaluation of the DAAS be made to assess: the training requirements or varying experience levels, the pilot workload in the ATC environment with unplanned route changes, and the viability of the reconfiguration concept for failures.

  7. Development of Improved Graphical Displays for an Advanced Outage Control Center, Employing Human Factors Principles for Outage Schedule Management

    SciTech Connect

    St Germain, Shawn Walter; Farris, Ronald Keith; Thomas, Kenneth David

    2015-09-01

    The long-term viability of existing nuclear power plants in the United States (U.S.) is dependent upon a number of factors, including maintaining high capacity factors, maintaining nuclear safety, and reducing operating costs, particularly those associated with refueling outages. Refueling outages typically take 20-30 days, and for existing light water NPPs in the U.S., the reactor cannot be in operation during the outage. Furthermore, given that many NPPs generate between $1-1.5 million/day in revenue when in operation, there is considerable interest in shortening the length of refueling outages. Yet refueling outages are highly complex operations, involving multiple concurrent and dependent activities that are somewhat challenging to coordinate; therefore, finding ways to improve refueling outage performance, while maintaining nuclear safety has proven to be difficult. The Advanced Outage Control Center (AOCC) project is a research and development (R&D) demonstration activity under the LWRS Program. LWRS is an R&D program that works closely with industry R&D programs to establish technical foundations for the licensing and managing of long-term, safe, and economical operation of current fleet of NPPs. As such, the LWRS Advanced Outage Control Center project has the goal of improving the management of commercial NPP refueling outages. To accomplish this goal, INL is developing an advanced outage control center (OCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. The overall focus is on developing an AOCC with the following capabilities that enables plant and OCC staff to; Collaborate in real-time to address emergent issues; Effectively communicate outage status to all workers involved in the outage; Effectively communicate discovered conditions in the field to the OCC; Provide real-time work status; Provide automatic pending support notifications

  8. Overview of Advanced Electromagnetic Propulsion Development at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Pencil, Eric J.; Kamhawi, Hani; Gilland, James H.; Arrington, Lynn A.

    2005-01-01

    NASA Glenn Research Center s Very High Power Electric Propulsion task is sponsored by the Energetics Heritage Project. Electric propulsion technologies currently being investigated under this program include pulsed electromagnetic plasma thrusters, magnetoplasmadynamic thrusters, helicon plasma sources as well as the systems models for high power electromagnetic propulsion devices. An investigation and evaluation of pulsed electromagnetic plasma thruster performance at energy levels up to 700 Joules is underway. On-going magnetoplasmadynamic thruster experiments will investigate applied-field performance characteristics of gas-fed MPDs. Plasma characterization of helicon plasma sources will provide additional insights into the operation of this novel propulsion concept. Systems models have been developed for high power electromagnetic propulsion concepts, such as pulsed inductive thrusters and magnetoplasmadynamic thrusters to enable an evaluation of mission-optimized designs.

  9. Certify for success: A methodology for human-centered certification of advanced aviation systems

    NASA Technical Reports Server (NTRS)

    Small, Ronald L.; Rouse, William B.

    1994-01-01

    This position paper uses the methodology in Design for Success as a basis for a human factors certification program. The Design for Success (DFS) methodology espouses a multi-step process to designing and developing systems in a human-centered fashion. These steps are as follows: (1) naturalizing - understand stakeholders and their concerns; (2) marketing - understand market-oriented alternatives to meeting stakeholder concerns; (3) engineering - detailed design and development of the system considering tradeoffs between technology, cost, schedule, certification requirements, etc.; (4) system evaluation - determining if the system meets its goal(s); and (5) sales and service - delivering and maintaining the system. Because the main topic of this paper is certification, we will focus our attention on step 4, System Evaluation, since it is the natural precursor to certification. Evaluation involves testing the system and its parts for their correct behaviors. Certification focuses not only on ensuring that the system exhibits the correct behaviors, but ONLY the correct behaviors.

  10. Recent Advances in Durability and Damage Tolerance Methodology at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Ransom, J. B.; Glaessgen, E. H.; Raju, I. S.; Harris, C. E.

    2007-01-01

    Durability and damage tolerance (D&DT) issues are critical to the development of lighter, safer and more efficient aerospace vehicles. Durability is largely an economic life-cycle design consideration whereas damage tolerance directly addresses the structural airworthiness (safety) of the vehicle. Both D&DT methodologies must address the deleterious effects of changes in material properties and the initiation and growth of damage that may occur during the vehicle s service lifetime. The result of unanticipated D&DT response is often manifested in the form of catastrophic and potentially fatal accidents. As such, durability and damage tolerance requirements must be rigorously addressed for commercial transport aircraft and NASA spacecraft systems. This paper presents an overview of the recent and planned future research in durability and damage tolerance analytical and experimental methods for both metallic and composite aerospace structures at NASA Langley Research Center (LaRC).

  11. Cost benefits of advanced software: A review of methodology used at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Joglekar, Prafulla N.

    1993-01-01

    To assist rational investments in advanced software, a formal, explicit, and multi-perspective cost-benefit analysis methodology is proposed. The methodology can be implemented through a six-stage process which is described and explained. The current practice of cost-benefit analysis at KSC is reviewed in the light of this methodology. The review finds that there is a vicious circle operating. Unsound methods lead to unreliable cost-benefit estimates. Unreliable estimates convince management that cost-benefit studies should not be taken seriously. Then, given external demands for cost-benefit estimates, management encourages software enginees to somehow come up with the numbers for their projects. Lacking the expertise needed to do a proper study, courageous software engineers with vested interests use ad hoc and unsound methods to generate some estimates. In turn, these estimates are unreliable, and the cycle continues. The proposed methodology should help KSC to break out of this cycle.

  12. Supplemental final environmental impact statement for advanced solid rocket motor testing at Stennis Space Center

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Since the Final Environmental Impact Statement (FEIS) and Record of Decision on the FEIS describing the potential impacts to human health and the environment associated with the program, three factors have caused NASA to initiate additional studies regarding these issues. These factors are: (1) The U.S. Army Corps of Engineers and the Environmental Protection Agency (EPA) agreed to use the same comprehensive procedures to identify and delineate wetlands; (2) EPA has given NASA further guidance on how best to simulate the exhaust plume from the Advanced Solid Rocket Motor (ASRM) testing through computer modeling, enabling more realistic analysis of emission impacts; and (3) public concerns have been raised concerning short and long term impacts on human health and the environment from ASRM testing.

  13. Manufacturing with the Sun

    NASA Technical Reports Server (NTRS)

    Murphy, Lawrence M.; Hauser, Steven G.; Clyne, Richard J.

    1991-01-01

    Concentrated solar radiation is now a viable alternative source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar induced surface transformation of materials (SISTM), solar based manufacturing, and solar pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offer greater potential for tomorrow, especially as applied to the radiation abundant environment available in space and on the lunar surface.

  14. Status Report on the Development of Micro-Scheduling Software for the Advanced Outage Control Center Project

    SciTech Connect

    Germain, Shawn St.; Thomas, Kenneth; Farris, Ronald; Joe, Jeffrey

    2014-09-01

    The long-term viability of existing nuclear power plants (NPPs) in the United States (U.S.) is dependent upon a number of factors, including maintaining high capacity factors, maintaining nuclear safety, and reducing operating costs, particularly those associated with refueling outages. Refueling outages typically take 20-30 days, and for existing light water NPPs in the U.S., the reactor cannot be in operation during the outage. Furthermore, given that many NPPs generate between $1-1.5 million/day in revenue when in operation, there is considerable interest in shortening the length of refueling outages. Yet, refueling outages are highly complex operations, involving multiple concurrent and dependent activities that are difficult to coordinate. Finding ways to improve refueling outage performance while maintaining nuclear safety has proven to be difficult. The Advanced Outage Control Center project is a research and development (R&D) demonstration activity under the Light Water Reactor Sustainability (LWRS) Program. LWRS is a R&D program which works with industry R&D programs to establish technical foundations for the licensing and managing of long-term, safe, and economical operation of current NPPs. The Advanced Outage Control Center project has the goal of improving the management of commercial NPP refueling outages. To accomplish this goal, this INL R&D project is developing an advanced outage control center (OCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. This report describes specific recent efforts to develop a capability called outage Micro-Scheduling. Micro-Scheduling is the ability to allocate and schedule outage support task resources on a sub-hour basis. Micro-Scheduling is the real-time fine-tuning of the outage schedule to react to the actual progress of the primary outage activities to ensure that support task resources are

  15. Advanced treatment by chemical oxidation of pulp and paper effluent from a plant manufacturing hardboard from waste paper.

    PubMed

    Tünay, O; Erdeml, E; Kabdaşli, I; Olmez, T

    2008-10-01

    This study attempts to evaluate the applicability of chemical oxidation processes to polish biologically treated effluent of a plant manufacturing hardboard from waste paper to comply with the discharge limit of 120 mg l(-1) chemical oxygen demand (COD). In the first step, a chemically assisted settling was applied. The optimum results were obtained with alum plus lime with the alum dose of 200 mg l(-1). In the second step, chemically assisted settling effluent was fed into an activated sludge system and over 80% COD removal was achieved. In the last step of the experimental study, a series of ozone oxidation and Fenton oxidation methods were tested to remove residual COD. Ozone oxidation provided 80% COD removal. An ozone dose of 40 mg min(-1) with a reaction time of two hours was found to be optimum. Catalytic ozonation by using ferric iron, as well as high pH ozonation, Fenton process and H2O2/O3 oxidation did not prove to be more efficient than plain ozonation under these study conditions.

  16. A novel mask proximity correction software combining accuracy and reduced writing time for the manufacturing of advanced photomasks

    NASA Astrophysics Data System (ADS)

    Schiavone, Patrick; Martin, Luc; Browning, Clyde; Farys, Vincent; Sundermann, Frank; Narukawa, Shogo; Takikawa, Tadahiko; Hayashi, Naoya

    2012-06-01

    The new generations of photomasks are seen to bring more and more challenges to the mask manufacturer. Maskshops face two conflicting requirements, namely improving pattern fidelity and reducing or at least maintaining acceptable writing time. These requirements are getting more and more challenging since pattern size continuously shrinks and data volumes continuously grows. Although the classical dose modulation Proximity Effect Correction is able to provide sufficient process control to the mainstream products, an increased number of published and wafer data show that the mask process is becoming a nonnegligible contributor to the 28nm technology yield. We will show in this paper that a novel approach of mask proximity effect correction is able to meet the dual challenge of the new generation of masks. Unlike the classical approach, the technique presented in this paper is based on a concurrent optimization of the dose and geometry of the fractured shots. Adding one more parameter allows providing the best possible compromise between accuracy and writing time since energy latitude can be taken into account as well. This solution is implemented in the Inscale software package from Aselta Nanographics. We have assessed the capability of this technology on several levels of a 28nm technology. On this set, the writing time has been reduced up to 25% without sacrificing the accuracy which at the same time has been improved significantly compared to the existing process. The experiments presented in the paper confirm that a versatile proximity effect correction strategy, combining dose and geometry modulation helps the users to tradeoff between resolution/accuracy and e-beam write time.

  17. The Center for Technology for Advanced Scientific Component Software (TASCS) Lawrence Livermore National Laboratory - Site Status Update

    SciTech Connect

    Epperly, T W

    2008-12-03

    This report summarizes LLNL's progress for the period April through September of 2008 for the Center for Technology for Advanced Scientific Component Software (TASCS) SciDAC. The TASCS project is organized into four major thrust areas: CCA Environment (72%), Component Technology Initiatives (16%), CCA Toolkit (8%), and User and Application Outreach & Support (4%). The percentage of LLNL's effort allocation is shown in parenthesis for each thrust area. Major thrust areas are further broken down into activity areas, LLNL's effort directed to each activity is shown in Figure 1. Enhancements, Core Tools, and Usability are all part of CCA Environment, and Software Quality is part of Component Technology Initiatives. The balance of this report will cover our accomplishments in each of these activity areas.

  18. An Aerodynamic Performance Evaluation of the NASA/Ames Research Center Advanced Concepts Flight Simulator. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Donohue, Paul F.

    1987-01-01

    The results of an aerodynamic performance evaluation of the National Aeronautics and Space Administration (NASA)/Ames Research Center Advanced Concepts Flight Simulator (ACFS), conducted in association with the Navy-NASA Joint Institute of Aeronautics, are presented. The ACFS is a full-mission flight simulator which provides an excellent platform for the critical evaluation of emerging flight systems and aircrew performance. The propulsion and flight dynamics models were evaluated using classical flight test techniques. The aerodynamic performance model of the ACFS was found to realistically represent that of current day, medium range transport aircraft. Recommendations are provided to enhance the capabilities of the ACFS to a level forecast for 1995 transport aircraft. The graphical and tabular results of this study will establish a performance section of the ACFS Operation's Manual.

  19. Spirituality and meaning in supportive care: spirituality- and meaning-centered group psychotherapy interventions in advanced cancer.

    PubMed

    Breitbart, William

    2002-05-01

    Existential and spiritual issues are at the frontier of new clinical and research focus in palliative and supportive care of cancer patients. As concepts of adequate supportive care expand beyond a focus on pain and physical symptom control, existential and spiritual issues such as meaning, hope and spirituality in general have received increased attention from supportive care clinicians and clinical researchers. This paper reviews the topics of spirituality and end-of-life care, defines spirituality, and suggests measures of spirituality that deal with two of its main components: faith/religious beliefs and meaning/spiritual well-being. These two constructs of spirituality are reviewed in terms of their role in supportive care. Finally, a review of existing psychotherapeutic interventions for spiritual suffering are reviewed and a novel meaning-centered group psychotherapy for advanced cancer patients is described.

  20. Parameter identification studies on the NASA/Ames Research Center Advanced Concepts Flight Simulator. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Mckavitt, Thomas P., Jr.

    1990-01-01

    The results of an aircraft parameters identification study conducted on the National Aeronautics and Space Administration/Ames Research Center Advanced Concepts Flight Simulator (ACFS) in conjunction with the Navy-NASA Joint Institute of Aeronautics are given. The ACFS is a commercial airline simulator with a design based on future technology. The simulator is used as a laboratory for human factors research and engineering as applied to the commercial airline industry. Parametric areas examined were engine pressure ratio (EPR), optimum long range cruise Mach number, flap reference speed, and critical take-off speeds. Results were compared with corresponding parameters of the Boeing 757 and 767 aircraft. This comparison identified two areas where improvements can be made: (1) low maximum lift coefficients (on the order of 20-25 percent less than those of a 757); and (2) low optimum cruise Mach numbers. Recommendations were made to those anticipated with the application of future technologies.

  1. Instructional Mddia Initiatives Focusing on the Educational Resources Center at Thirteen/WNET. What's Up in Factories?: Introducing Teachers and Students to the Dynamic World of Modern Manufacturing.

    ERIC Educational Resources Information Center

    Donlevy, James G.; Donlevy, Tia Rice

    2000-01-01

    Describes "What's Up in Factories?", an experimental curriculum developed by WNET television that combines video and a variety of interactive activities, including field trips to manufacturing facilities. Discusses goals that include an appreciation of manufacturing, learning about current trends and innovations, and discovering and…

  2. Mechanical Prototyping and Manufacturing Internship

    NASA Technical Reports Server (NTRS)

    Grenfell, Peter

    2016-01-01

    The internship was located at the Johnson Space Center (JSC) Innovation Design Center (IDC), which is a facility where the JSC workforce can meet and conduct hands-on innovative design, fabrication, evaluation, and testing of ideas and concepts relevant to NASA's mission. The tasks of the internship included mechanical prototyping design and manufacturing projects in service of research and development as well as assisting the users of the IDC in completing their manufacturing projects. The first project was to manufacture hatch mechanisms for a team in the Systems Engineering and Project Advancement Program (SETMAP) hexacopter competition. These mechanisms were intended to improve the performance of the servomotors and offer an access point that would also seal to prevent cross-contamination. I also assisted other teams as they were constructing and modifying their hexacopters. The success of this competition demonstrated a proof of concept for aerial reconnaissance and sample return to be potentially used in future NASA missions. I also worked with Dr. Kumar Krishen to prototype an improved thermos and a novel, portable solar array. Computer-aided design (CAD) software was used to model the parts for both of these projects. Then, 3D printing as well as conventional techniques were used to produce the parts. These prototypes were then subjected to trials to determine the success of the designs. The solar array is intended to work in a cluster that is easy to set up and take down and doesn't require powered servomechanisms. It could be used terrestrially in areas not serviced by power grids. Both projects improve planetary exploration capabilities to future astronauts. Other projects included manufacturing custom rail brackets for EG-2, assisting engineers working on underwater instrument and tool cases for the NEEMO project, and helping to create mock-up parts for Space Center Houston. The use of the IDC enabled efficient completion of these projects at

  3. Advancing educational continuity in primary care residencies: an opportunity for patient-centered medical homes.

    PubMed

    Bowen, Judith L; Hirsh, David; Aagaard, Eva; Kaminetzky, Catherine P; Smith, Marie; Hardman, Joseph; Chheda, Shobhina G

    2015-05-01

    Continuity of care is a core value of patients and primary care physicians, yet in graduate medical education (GME), creating effective clinical teaching environments that emphasize continuity poses challenges. In this Perspective, the authors review three dimensions of continuity for patient care-informational, longitudinal, and interpersonal-and propose analogous dimensions describing continuity for learning that address both residents learning from patient care and supervisors and interprofessional team members supporting residents' competency development. The authors review primary care GME reform efforts through the lens of continuity, including the growing body of evidence that highlights the importance of longitudinal continuity between learners and supervisors for making competency judgments. The authors consider the challenges that primary care residency programs face in the wake of practice transformation to patient-centered medical home models and make recommendations to maximize the opportunity that these practice models provide. First, educators, researchers, and policy makers must be more precise with terms describing various dimensions of continuity. Second, research should prioritize developing assessments that enable the study of the impact of interpersonal continuity on clinical outcomes for patients and learning outcomes for residents. Third, residency programs should establish program structures that provide informational and longitudinal continuity to enable the development of interpersonal continuity for care and learning. Fourth, these educational models and continuity assessments should extend to the level of the interprofessional team. Fifth, policy leaders should develop a meaningful recognition process that rewards academic practices for training the primary care workforce.

  4. Development of a Batch Fabrication Process for Chemical Nanosensors: Recent Advancements at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Biaggi-Labiosa, Azlin M.

    2014-01-01

    A major objective in aerospace sensor development is to produce sensors that are small in size, easy to batch fabricate and low in cost, and have low power consumption. Chemical sensors involving nanostructured materials can provide these characteristics as well as the potential for the development of sensor systems with unique properties and improved performance. However, the fabrication and processing of nanostructures for sensor applications currently is limited by the ability to control their location on the sensor platform, which in turn hinders the progress for batch fabrication. This presentation will discuss the following: the development of a novel room temperature methane (CH4) sensor fabricated using porous tin oxide (SnO2) nanorods as the sensing material, the advantages of using nanomaterials in sensor designs, the challenges encountered with the integration of nanostructures into microsensordevices, and the different methods that have been attempted to address these challenges. An approach for the mass production of sensors with nanostructures using a method developed by our group at the NASA Glenn Research Center to control the alignment of nanostructures onto a sensor platform will also be described.

  5. Recent advances in carbon-carbon substrate technology at NASA. Langley Research Center

    NASA Technical Reports Server (NTRS)

    Ransone, Philip O.; Yamaki, Y. Robert; Maahs, Howard G.

    1992-01-01

    A comparison of specific strengths of candidate high-temperature materials as a function of temperature is shown. From this comparison, it is apparent why there is an interest in carbon-carbon composites for applications as a strong, light-weight thermal protection system (TPS), or as hot structure, for applications above 2500 F. The lower bound of the carbon-carbon band is representative of the tensile strength of cross-ply Advanced Carbon-Carbon (ACC). The upper bound represents capabilities of various experimental carbon-carbon composites. Thin carbon-carbon composites, such as would be used as TPS panels or hot aero-structure, are usually constructed of layups of 2-D fabrics of carbon-fiber yarns (tows). Although the in-plane strengths of these composites can be very attractive, a major problem area is low interlaminar strength. The low interlaminar strength is the result of a relatively weak carbon matrix and poor interaction between the fibers and matrix. The purpose of this paper is to discuss strategies being employed to improve the interlaminar strengths of the materials at the upper bound of the carbon-carbon band, and to present some recent encouraging results. The emphasis of these strategies is to improve interlaminar shear and tensile strengths while maintaining, or even improving, the inplane properties.

  6. Advanced manufacturing development of a composite empennage component for L-1011 aircraft. Phase 3: Production readiness verification testing

    NASA Technical Reports Server (NTRS)

    Jackson, A.; Sandifer, J.; Sandorff, P.; Vancleave, R.

    1984-01-01

    Twenty-two specimens of each of two key structural elements of the Advance Composite Vertical Fin (ACVF) were fabricated and tested. One element represented the front spar at the fuselage attachment area and the other element represented the cover at the fuselage joint area. Ten specimens of each element were selected for static testing. The coefficient of variation resulting from the tests was 3.28 percent for the ten cover specimens and 6.11 percent for the ten spar specimens, which compare well with metallic structures. The remaining twelve cover and twelve spar specimens were durability tested in environmental chambers which permitted the temperature and humidity environment to be cycled as well as the applied loads. Results of the durability tests indicated that such components will survive the service environment.

  7. Manufacturing technology

    SciTech Connect

    Blaedel, K L

    1998-01-01

    The mission of the Manufacturing Technology thrust area at Lawrence Livermore National Laboratory (LLNL) has been to have an adequate base of manufacturing technology, not necessarily resident at LLNL, to conduct their future business. The specific goals were (1) to develop an understanding of fundamental fabrication processes; (2) to construct general purpose process models that have wide applicability; (3) to document their findings and models in journals; (4) to transfer technology to LLNL programs, industry, and colleagues; and (5) to develop continuing relationships with the industrial and academic communities to advance their collective understanding of fabrication processes. In support of this mission, two projects were reported here, each of which explores a way to bring higher precision to the manufacturing challenges that we face over the next few years. The first, ''A Spatial-Frequency-Domain Approach to Designing a Precision Machine Tools,'' is an overall view of how they design machine tools and instruments to make or measure workpieces that are specified in terms of the spatial frequency content of the residual errors of the workpiece surface. This represents an improvement of an ''error budget,'' a design tool that saw significant development in the early 1980's, and has been in active use since then. The second project, ''Micro-Drilling of ICF Capsules,'' is an attempt to define the current state in commercial industry for drilling small holes, particularly laser-drilling. The report concludes that 1-{micro}m diameter holes cannot currently be drilled to high aspect ratios, and then defines the engineering challenges that will have to be overcome to machine holes small enough for NIF capsules.

  8. Manufacturers' Views of Vocational Education.

    ERIC Educational Resources Information Center

    Nunez, Ann R.; Russell, Jill Frymier

    A survey of manufacturers was conducted by the National Association of Manufacturers (NAM) and the National Center for Research in Vocational Education to elicit the views of NAM members about vocational education--the effectiveness of vocational education, the collaborative activities between manufacturers and vocational education, and…

  9. Advanced cryogenic tank development status

    NASA Astrophysics Data System (ADS)

    Braun, G. F.; Tack, W. T.; Scholz, E. F.

    1993-06-01

    Significant advances have been made in the development of materials, structures, and manufacturing technologies for the next generation of cryogenic propellant tanks under the auspices of a joint U.S. Air Force/NASA sponsored advanced development program. This paper summarizes the achievements of this three-year program, particularly in the evolution and properties of Weldalite 049, net shape component technology, Al-Li welding technology, and efficient manufacturing concepts. Results of a recent mechanical property characterization of a full-scale integrally stiffened barrel panel extrusion are presented, as well as plans for an additional weld process optimization program using response surface design of experiment techniques. A further discussion is given to the status of hardware completed for the Advanced Manufacturing Development Center and Martin Marietta's commitment to the integration of these technologies into the production of low-cost, light-weight cryogenic propellant tanks.

  10. Turbine Manufacture

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The machinery pictured is a set of Turbodyne steam turbines which power a sugar mill at Bell Glade, Florida. A NASA-developed computer program called NASTRAN aided development of these and other turbines manufactured by Turbodyne Corporation's Steam Turbine Division, Wellsville, New York. An acronym for NASA Structural Analysis Program, NASTRAN is a predictive tool which advises development teams how a structural design will perform under service use conditions. Turbodyne uses NASTRAN to analyze the dynamic behavior of steam turbine components, achieving substantial savings in development costs. One of the most widely used spinoffs, NASTRAN is made available to private industry through NASA's Computer Software Management Information Center (COSMIC) at the University of Georgia.

  11. Advancements in Data Access at the IRIS Data Management Center to Broaden Data Use

    NASA Astrophysics Data System (ADS)

    Benson, R. B.; Trabant, C. M.; Ahern, T. K.

    2013-12-01

    The IRIS Data Management Center (DMC) has been serving digital seismic data for more than 20 years and has offered a variety of access mechanisms that have stood the test of time. However, beginning in 2010, and in response to multiple needs being requested from the IRIS DMC, we have developed web service interfaces to access our primary data repository. These new interfaces have rapidly grown in popularity. In 2013, the third full year of their operation, these services were responsible for half of all the data shipped from the DMC. In the same time period, the amount of data shipped from the other data access mechanisms has also increased. This non-linear growth of data shipments reflects the increased data usage by the research community. We believe that our new web service interfaces are well suited to fit future data access needs and signify a significant evolution in integrating different scientific data sets. Based on standardized web technologies, support for writing access software is ubiquitous. As fundamentally programmatic interfaces, the services are well suited for integration into data processing systems, in particular large-scale data processing systems. Their programmatic nature also makes then well suited for use with brokering systems where, for example, data from multiple disciplines can be integrated. In addition to providing access to raw data, the DMC created web services that apply simple, on-the-fly processing and format conversion. Processing the data (e.g. converting to Earth units) and formatting the result into something generally usable (e.g. ASCII) removes important barriers for users working in other disciplines. The end result is that we are shipping a much larger amount of data in a manner more directly usable by users. Many of these principles will be applied to the DMC's future work in the NSF's EarthCube Web Service Building Blocks project.

  12. Recent Advances in Hydrogen Peroxide Propulsion Test Capability at NASA's Stennis Space Center E-Complex

    NASA Technical Reports Server (NTRS)

    Jacks, Thomas E.; Beisler, Michele

    2003-01-01

    In recent years, the rocket propulsion test capability at NASA's John C. Stennis Space Center's (SSC) E-Complex has been enhanced to include facilitization for hydrogen peroxide (H2O2) based ground testing. In particular, the E-3 test stand has conducted numerous test projects that have been reported in the open literature. These include combustion devices as simple as small-scale catalyst beds, and larger devices such as ablative thrust chambers and a flight-type engine (AR2-3). Consequently, the NASA SSC test engineering and operations knowledge base and infrastructure have grown considerably in order to conduct safe H2O2 test operations with a variety of test articles at the component and engine level. Currently, the E-Complex has a test requirement for a hydrogen peroxide based stage test. This new development, with its unique set of requirements, has motivated the facilitization for hydrogen peroxide propellant use at the E-2 Cell 2 test position in addition to E-3. Since the E-2 Cell 2 test position was not originally designed as a hydrogen peroxide test stand, a facility modernization-improvement project was planned and implemented in FY 2002-03 to enable this vertical engine test stand to accomodate H2O2. This paper discusses the ongoing enhancement of E-Complex ground test capability, specifically at the E-3 stand (Cell 1 and Cell 2) and E-2 Cell 2 stand, that enable current and future customers considerable test flexibility and operability in conducting their peroxide based rocket R&D efforts.

  13. Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

    2015-01-01

    NASA Glenn Research Center (GRC) developed a non-nuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASC), a Dual Convertor Controller (DCC) EM (engineering model) 2 & 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University/Applied Physics Laboratory (JHU/APL) to actively control a pair of Advanced Stirling Convertors (ASC). The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS) which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASC's in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and supercapacitor. A load profile, created based on data from several missions, tested the RPS and RSIL ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 V or exceeded 36 V. Once operation was verified with the DASCS, the tests were repeated with actual operating ASC's. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

  14. Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer

    PubMed Central

    Applebaum, Allison J.; Lichtenthal, Wendy G.; Pessin, Hayley A.; Radomski, Julia N.; Gökbayrak, N. Simay; Katz, Aviva M.; Rosenfeld, Barry; Breitbart, William

    2013-01-01

    Objective The generalizability of palliative care intervention research is often limited by high rates of study attrition. This study examined factors associated with attrition from a randomized controlled trial comparing meaning-centered group psychotherapy (MCGP), an intervention designed to help advanced cancer patients sustain or enhance their sense of meaning to the supportive group psychotherapy (SGP), a standardized support group. Methods Patients with advanced solid tumor cancers (n = 153) were randomized to eight sessions of either the MCGP or SGP. They completed assessments of psychosocial, spiritual, and physical well-being pretreatment, midtreatment, and 2 months post-treatment. Attrition was assessed in terms of the percent of participants who failed to complete these assessments, and demographic, psychiatric, medical, and study-related correlates of attrition were examined for the participants in each of these categories. Results The rates of attrition at these time points were 28.1%, 17.7%, and 11.1%, respectively; 43.1% of the participants (66 of 153) completed the entire study. The most common reason for dropout was patients feeling too ill. Attrition rates did not vary significantly between study arms. The participants who dropped out pretreatment reported less financial concerns than post-treatment dropouts, and the participants who dropped out of the study midtreatment had poorer physical health than treatment completers. There were no other significant associations between attrition and any demographic, medical, psychiatric, or study-related variables. Conclusions These findings highlight the challenge of maintaining advanced cancer patients in longitudinal research and suggest the need to consider alternative approaches (e.g., telemedicine) for patients who might benefit from group interventions but are too ill to travel. PMID:21751295

  15. Advanced Outage and Control Center: Strategies for Nuclear Plant Outage Work Status Capabilities

    SciTech Connect

    Gregory Weatherby

    2012-05-01

    The research effort is a part of the Light Water Reactor Sustainability (LWRS) Program. LWRS is a research and development program sponsored by the Department of Energy, performed in close collaboration with industry to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. The LWRS Program serves to help the US nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The Outage Control Center (OCC) Pilot Project was directed at carrying out the applied research for development and pilot of technology designed to enhance safe outage and maintenance operations, improve human performance and reliability, increase overall operational efficiency, and improve plant status control. Plant outage management is a high priority concern for the nuclear industry from cost and safety perspectives. Unfortunately, many of the underlying technologies supporting outage control are the same as those used in the 1980’s. They depend heavily upon large teams of staff, multiple work and coordination locations, and manual administrative actions that require large amounts of paper. Previous work in human reliability analysis suggests that many repetitive tasks, including paper work tasks, may have a failure rate of 1.0E-3 or higher (Gertman, 1996). With between 10,000 and 45,000 subtasks being performed during an outage (Gomes, 1996), the opportunity for human error of some consequence is a realistic concern. Although a number of factors exist that can make these errors recoverable, reducing and effectively coordinating the sheer number of tasks to be performed, particularly those that are error prone, has the potential to enhance outage efficiency and safety. Additionally, outage management requires precise coordination of work groups that do not always share similar objectives. Outage

  16. Surgical approach for ulcerated locally advanced breast cancer. A single Center experience: a retrospective study.

    PubMed

    Laforgia, Rita; Punzo, Clelia; Panebianco, Annunziata; Volpi, Annalisa; Minafra, Marina; Sederino, Maria Grazia

    2017-01-12

    L’obiettivo del nostro studio è la valutazione della strategia chirurgica più idonea nei casi di LABC (Locally Advanced Breast Cancer) in condizioni di ulcerazione e sanguinamento. La diagnosi clinica del LABC prevede nella maggior parte dei casi una massa mammaria estesa associata ad edema, eritema, retrazione e sanguinamento, dolore, superficie cutanea irregolare e coinvolgimento linfonodale. L’intervento chirurgico di scelta per le forme T3-T4 è la mastectomia radicale che rappresenta un trattamento adeguato per il controllo locale della patologia. In caso di forme localmente avanzate e ulcerate, pur essendo forme inoperabili, l’exeresi chirurgica si rende necessaria per una bonifica locale. La presenza di fenomeni di ulcerazione e sanguinamento non rende possibile avviare un trattamento chemioterapico neoadiuvante ed è necessario eseguire interventi chirurgici palliativi. Il trattamento chirurgico stesso richiede mutilazioni ampie ed associate procedure di chirurgia plastica. Spesso per l’estensione della malattia ed il sovvertimento del corpus mammae durante l’exeresi chirurgica della mammella, la sezione su zone esenti da neoplasia non consente la chiusura immediata dei lembi. Abbiamo considerato, su un campione di 288 pazienti affette da carcinoma mammario, 11 donne con forme avanzate fra T4a e T4c (3.8%). E’ stata posta indicazione a trattamento chirurgico perché pazienti provenienti dal Pronto Soccorso con anemizzazione per neoplasie avanzate ulcerate e sanguinanti, non candidabili in prima istanza a chemioterapia neoadiuvante citoriduttiva. Le procedure adoperate per la ricostruzione della mammella sono state in 2 pazienti la rotazione di un lembo muscolo cutaneo, in 4 casi un innesto cutaneo prelevato dalla coscia, in 4 casi è stata utilizzata una matrice dermica biologica - sostituto cutaneo (INTEGRA) che è stata poi sostituita con un successivo innesto cutaneo a distanza di circa 20-30 giorni. Sono state osservate recidive in 2 casi

  17. Energy Saving Melting and Revert Reduction Technology (Energy SMARRT): Manufacturing Advanced Engineered Components Using Lost Foam Casting Technology

    SciTech Connect

    Littleton, Harry; Griffin, John

    2011-07-31

    This project was a subtask of Energy Saving Melting and Revert Reduction Technology (Energy SMARRT) Program. Through this project, technologies, such as computer modeling, pattern quality control, casting quality control and marketing tools, were developed to advance the Lost Foam Casting process application and provide greater energy savings. These technologies have improved (1) production efficiency, (2) mechanical properties, and (3) marketability of lost foam castings. All three reduce energy consumption in the metals casting industry. This report summarizes the work done on all tasks in the period of January 1, 2004 through June 30, 2011. Current (2011) annual energy saving estimates based on commercial introduction in 2011 and a market penetration of 97% by 2020 is 5.02 trillion BTU's/year and 6.46 trillion BTU's/year with 100% market penetration by 2023. Along with these energy savings, reduction of scrap and improvement in casting yield will result in a reduction of the environmental emissions associated with the melting and pouring of the metal which will be saved as a result of this technology. The average annual estimate of CO2 reduction per year through 2020 is 0.03 Million Metric Tons of Carbon Equivalent (MM TCE).

  18. Civil Engineering Applications of Ground Penetrating Radar Recent Advances @ the ELEDIA Research Center

    NASA Astrophysics Data System (ADS)

    Salucci, Marco; Tenuti, Lorenza; Nardin, Cristina; Oliveri, Giacomo; Viani, Federico; Rocca, Paolo; Massa, Andrea

    2014-05-01

    The application of non-destructive testing and evaluation (NDT/NDE) methodologies in civil engineering has raised a growing interest during the last years because of its potential impact in several different scenarios. As a consequence, Ground Penetrating Radar (GPR) technologies have been widely adopted as an instrument for the inspection of the structural stability of buildings and for the detection of cracks and voids. In this framework, the development and validation of GPR algorithms and methodologies represents one of the most active research areas within the ELEDIA Research Center of the University of Trento. More in detail, great efforts have been devoted towards the development of inversion techniques based on the integration of deterministic and stochastic search algorithms with multi-focusing strategies. These approaches proved to be effective in mitigating the effects of both nonlinearity and ill-posedness of microwave imaging problems, which represent the well-known issues arising in GPR inverse scattering formulations. More in detail, a regularized multi-resolution approach based on the Inexact Newton Method (INM) has been recently applied to subsurface prospecting, showing a remarkable advantage over a single-resolution implementation [1]. Moreover, the use of multi-frequency or frequency-hopping strategies to exploit the information coming from GPR data collected in time domain and transformed into its frequency components has been proposed as well. In this framework, the effectiveness of the multi-resolution multi-frequency techniques has been proven on synthetic data generated with numerical models such as GprMax [2]. The application of inversion algorithms based on Bayesian Compressive Sampling (BCS) [3][4] to GPR is currently under investigation, as well, in order to exploit their capability to provide satisfactory reconstructions in presence of single and multiple sparse scatterers [3][4]. Furthermore, multi-scaling approaches exploiting level

  19. Advances in Land Data Assimilation at the NASA Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Reichle, Rolf

    2009-01-01

    Research in land surface data assimilation has grown rapidly over the last decade. In this presentation we provide a brief overview of key research contributions by the NASA Goddard Space Flight Center (GSFC). The GSFC contributions to land assimilation primarily include the continued development and application of the Land Information System (US) and the ensemble Kalman filter (EnKF). In particular, we have developed a method to generate perturbation fields that are correlated in space, time, and across variables and that permit the flexible modeling of errors in land surface models and observations, along with an adaptive filtering approach that estimates observation and model error input parameters. A percentile-based scaling method that addresses soil moisture biases in model and observational estimates opened the path to the successful application of land data assimilation to satellite retrievals of surface soil moisture. Assimilation of AMSR-E surface soil moisture retrievals into the NASA Catchment model provided superior surface and root zone assimilation products (when validated against in situ measurements and compared to the model estimates or satellite observations alone). The multi-model capabilities of US were used to investigate the role of subsurface physics in the assimilation of surface soil moisture observations. Results indicate that the potential of surface soil moisture assimilation to improve root zone information is higher when the surface to root zone coupling is stronger. Building on this experience, GSFC leads the development of the Level 4 Surface and Root-Zone Soil Moisture (L4_SM) product for the planned NASA Soil-Moisture-Active-Passive (SMAP) mission. A key milestone was the design and execution of an Observing System Simulation Experiment that quantified the contribution of soil moisture retrievals to land data assimilation products as a function of retrieval and land model skill and yielded an estimate of the error budget for the

  20. Manufacturing Success

    ERIC Educational Resources Information Center

    Reese, Susan

    2007-01-01

    According to the National Association of Manufacturers (NAM), "manufacturing is the engine that drives American prosperity". When NAM and its research and education arm, The Manufacturing Institute, released the handbook, "The Facts About Modern Manufacturing," in October 2006, NAM President John Engler noted, that…

  1. Energy 101: Clean Energy Manufacturing

    ScienceCinema

    None

    2016-07-12

    Most of us have a basic understanding of manufacturing. It's how we convert raw materials, components, and parts into finished goods that meet our essential needs and make our lives easier. But what about clean energy manufacturing? Clean energy and advanced manufacturing have the potential to rejuvenate the U.S. manufacturing industry and open pathways to increased American competitiveness. Watch this video to learn more about this exciting movement and to see some of these innovations in action.

  2. Energy 101: Clean Energy Manufacturing

    SciTech Connect

    2015-07-09

    Most of us have a basic understanding of manufacturing. It's how we convert raw materials, components, and parts into finished goods that meet our essential needs and make our lives easier. But what about clean energy manufacturing? Clean energy and advanced manufacturing have the potential to rejuvenate the U.S. manufacturing industry and open pathways to increased American competitiveness. Watch this video to learn more about this exciting movement and to see some of these innovations in action.

  3. Education of Advanced Biotechnologists of Kitakyushu National College of Technology

    NASA Astrophysics Data System (ADS)

    Kawahara, Hiroharu

    The Cell Engineering Center was established in October, 2003 to research and develop manufacturing technologies and cell engineering technologies with human cell lines, which boost their uniqueness. The center serves as a base for advancing industrial development and creating new industries in Kitakyushu City area. One of the features in this center's activities is to promote technology exchanges between the students and researchers in private firms and to facilitate developed biotechnologies transferred to the private sectors. The Cell Engineering Center aims to train the advanced biotechnologists who have abilities for applying for patents, international communications, and leaderships. In this work, the educational and research activities in the Cell Engineering Center will be reported.

  4. [Advanced Composites Technology Initiatives

    NASA Technical Reports Server (NTRS)

    Julian, Mark R.

    2002-01-01

    This final report closes out the W02 NASA Grant #NCC5-646. The FY02 grant for advanced technology initiatives through the Advanced Composites Technology Institute in Bridgeport, WV, at the Robert C. Byrd Institute (RCBI) Bridgeport Manufacturing Technology Center, is complete; all funding has been expended. RCBI continued to expand access to technology; develop and implement a workforce-training curriculum; improve material development; and provide prototyping and demonstrations of new and advanced composites technologies for West Virginia composites firms. The FY 02 efforts supported workforce development, technical training and the HST development effort of a super-lightweight composite carrier prototype and expanded the existing technical capabilities of the growing aerospace industry across West Virginia to provide additional support for NASA missions. Additionally, the Composites Technology and Training Center was awarded IS0 9001 - 2000 certification and Cleanroom Class 1000 certification during this report period.

  5. Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

    2015-01-01

    NASA Glenn Research Center developed a nonnuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASCs), Dual Convertor Controller (DCC) EMs (engineering models) 2 and 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University Applied Physics Laboratory (JHU/APL) to actively control a pair of ASCs. The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS), which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASCs in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and super-capacitor. A load profile, created based on data from several missions, tested the RPS's and RSIL's ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 volts or exceeded 36 volts. Once operation was verified with the DASCS, the tests were repeated with actual operating ASCs. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

  6. Supporting Development for the Stirling Radioisotope Generator and Advanced Stirling Technology Development at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Thieme, Lanny G.; Schreiber, Jeffrey G.

    2005-01-01

    A high-efficiency, 110-We (watts electric) Stirling Radioisotope Generator (SRG110) for possible use on future NASA Space Science missions is being developed by the Department of Energy, Lockheed Martin, Stirling Technology Company (STC), and NASA Glenn Research Center (GRC). Potential mission use includes providing spacecraft onboard electric power for deep space missions and power for unmanned Mars rovers. GRC is conducting an in-house supporting technology project to assist in SRG110 development. One-, three-, and six-month heater head structural benchmark tests have been completed in support of a heater head life assessment. Testing is underway to evaluate the key epoxy bond of the permanent magnets to the linear alternator stator lamination stack. GRC has completed over 10,000 hours of extended duration testing of the Stirling convertors for the SRG110, and a three-year test of two Stirling convertors in a thermal vacuum environment will be starting shortly. GRC is also developing advanced technology for Stirling convertors, aimed at substantially improving the specific power and efficiency of the convertor and the overall generator. Sunpower, Inc. has begun the development of a lightweight Stirling convertor, under a NASA Research Announcement (NRA) award, that has the potential to double the system specific power to about 8 We/kg. GRC has performed random vibration testing of a lower-power version of this convertor to evaluate robustness for surviving launch vibrations. STC has also completed the initial design of a lightweight convertor. Status of the development of a multi-dimensional computational fluid dynamics code and high-temperature materials work on advanced superalloys, refractory metal alloys, and ceramics are also discussed.

  7. Sorafenib treatment of radioiodine-refractory advanced thyroid cancer in daily clinical practice: a cohort study from a single center.

    PubMed

    Gallo, Marco; Michelon, Federica; Castiglione, Anna; Felicetti, Francesco; Viansone, Alessandro Adriano; Nervo, Alice; Zichi, Clizia; Ciccone, Giovannino; Piovesan, Alessandro; Arvat, Emanuela

    2015-08-01

    Treatment options for recurrent or metastatic differentiated thyroid cancer (DTC) refractory to radioactive iodine (RAI) are inadequate. Multitargeted kinase inhibitors have recently shown promising results in phase 2-3 studies. This retrospective study aimed to document our clinical experience on the effects of sorafenib in the setting of daily clinical practice. Retrospective study evaluating the efficacy and safety of sorafenib in a cohort of patients consecutively treated with sorafenib at a single center. Twenty patients with advanced RAI-refractory thyroid carcinoma were enrolled (March 2011-March 2014). Patients generally started with 400 mg of sorafenib twice daily, tapering the dose in case of side effects. Radiological response and toxicity were measured during follow-up, together with safety parameters. CT scans were performed by a single experienced radiologist every 3-4 months. Five patients stopped sorafenib within 90 days due to severe toxicities. Median progression-free survival was 248 days. Five patients had a partial response (PR), achieved in all cases within 3 months, whereas 5 had stable disease (SD) at 12 months. Durable response rate (PR plus SD) for at least 6 months was 50 %, among those who received sorafenib for at least 3 months. Commonest adverse events included skin toxicity, gastrointestinal and constitutional symptoms. In our cohort of patients with advanced RAI-refractory thyroid carcinoma, sorafenib confirmed antitumor activity leading to SD or PR in the majority of cases, at the expense of clinically relevant side effects. More effective and tolerable agents are still needed in the treatment of RAI-refractory DTC.

  8. An Investigation of the North Carolina Center for the Advancement of Teaching and Its Possible Influence on Experienced Teacher Retention: A Companion Dissertation

    ERIC Educational Resources Information Center

    White, Jenny Blalock

    2015-01-01

    The purpose of this companion, qualitative case study was to examine the degree to which the residential professional development model at the North Carolina Center for the Advancement of Teaching (NCCAT) possibly influenced the retention of experienced teachers. The researcher sought to discover the ways and to what degree NCCAT had discharged…

  9. Recent CESAR (Center for Engineering Systems Advanced Research) research activities in sensor based reasoning for autonomous machines

    SciTech Connect

    Pin, F.G.; de Saussure, G.; Spelt, P.F.; Killough, S.M.; Weisbin, C.R.

    1988-01-01

    This paper describes recent research activities at the Center for Engineering Systems Advanced Research (CESAR) in the area of sensor based reasoning, with emphasis being given to their application and implementation on our HERMIES-IIB autonomous mobile vehicle. These activities, including navigation and exploration in a-priori unknown and dynamic environments, goal recognition, vision-guided manipulation and sensor-driven machine learning, are discussed within the framework of a scenario in which an autonomous robot is asked to navigate through an unknown dynamic environment, explore, find and dock at the panel, read and understand the status of the panel's meters and dials, learn the functioning of a process control panel, and successfully manipulate the control devices of the panel to solve a maintenance emergency problems. A demonstration of the successful implementation of the algorithms on our HERMIES-IIB autonomous robot for resolution of this scenario is presented. Conclusions are drawn concerning the applicability of the methodologies to more general classes of problems and implications for future work on sensor-driven reasoning for autonomous robots are discussed. 8 refs., 3 figs.

  10. Advancing Efficient All-Electron Electronic Structure Methods Based on Numeric Atom-Centered Orbitals for Energy Related Materials

    NASA Astrophysics Data System (ADS)

    Blum, Volker

    This talk describes recent advances of a general, efficient, accurate all-electron electronic theory approach based on numeric atom-centered orbitals; emphasis is placed on developments related to materials for energy conversion and their discovery. For total energies and electron band structures, we show that the overall accuracy is on par with the best benchmark quality codes for materials, but scalable to large system sizes (1,000s of atoms) and amenable to both periodic and non-periodic simulations. A recent localized resolution-of-identity approach for the Coulomb operator enables O (N) hybrid functional based descriptions of the electronic structure of non-periodic and periodic systems, shown for supercell sizes up to 1,000 atoms; the same approach yields accurate results for many-body perturbation theory as well. For molecular systems, we also show how many-body perturbation theory for charged and neutral quasiparticle excitation energies can be efficiently yet accurately applied using basis sets of computationally manageable size. Finally, the talk highlights applications to the electronic structure of hybrid organic-inorganic perovskite materials, as well as to graphene-based substrates for possible future transition metal compound based electrocatalyst materials. All methods described here are part of the FHI-aims code. VB gratefully acknowledges contributions by numerous collaborators at Duke University, Fritz Haber Institute Berlin, TU Munich, USTC Hefei, Aalto University, and many others around the globe.

  11. Photoluminescence of radiation-induced color centers in lithium fluoride thin films for advanced diagnostics of proton beams

    SciTech Connect

    Piccinini, M. Ampollini, A.; Picardi, L.; Ronsivalle, C.; Bonfigli, F.; Libera, S.; Vincenti, M. A.; Montereali, R. M.; Ambrosini, F.; Nichelatti, E.

    2015-06-29

    Systematic irradiation of thermally evaporated 0.8 μm thick polycrystalline lithium fluoride films on glass was performed by proton beams of 3 and 7 MeV energies, produced by a linear accelerator, in a fluence range from 10{sup 11} to 10{sup 15} protons/cm{sup 2}. The visible photoluminescence spectra of radiation-induced F{sub 2} and F{sub 3}{sup +} laser active color centers, which possess almost overlapping absorption bands at about 450 nm, were measured under laser pumping at 458 nm. On the basis of simulations of the linear energy transfer with proton penetration depth in LiF, it was possible to obtain the behavior of the measured integrated photoluminescence intensity of proton irradiated LiF films as a function of the deposited dose. The photoluminescence signal is linearly dependent on the deposited dose in the interval from 10{sup 3} to about 10{sup 6 }Gy, independently from the used proton energies. This behavior is very encouraging for the development of advanced solid state radiation detectors based on optically transparent LiF thin films for proton beam diagnostics and two-dimensional dose mapping.

  12. Guidelines for Implementation of an Advanced Outage Control Center to Improve Outage Coordination, Problem Resolution, and Outage Risk Management

    SciTech Connect

    St. Germain, Shawn W.; Farris, Ronald K.; Whaley, April M.; Medema, Heather D.; Gertman, David I.

    2014-09-01

    This research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which is a research and development (R&D) program sponsored by Department of Energy (DOE) and performed in close collaboration with industry R&D programs that provide the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. The LWRS program serves to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The purpose of this research is to improve management of nuclear power plant (NPP) outages through the development of an advanced outage control center (AOCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. This technical report for industry implementation outlines methods and considerations for the establishment of an AOCC. This report provides a process for implementation of a change management plan, evaluation of current outage processes, the selection of technology, and guidance for the implementation of the selected technology. Methods are presented for both adoption of technologies within an existing OCC and for a complete OCC replacement, including human factors considerations for OCC design and setup.

  13. The Joint Space Operations Center Mission System and the Advanced Research, Collaboration, and Application Development Environment Status Update 2016

    NASA Astrophysics Data System (ADS)

    Murray-Krezan, Jeremy; Howard, Samantha; Sabol, Chris; Kim, Richard; Echeverry, Juan

    2016-05-01

    The Joint Space Operations Center (JSpOC) Mission System (JMS) is a service-oriented architecture (SOA) infrastructure with increased process automation and improved tools to enhance Space Situational Awareness (SSA) performed at the US-led JSpOC. The Advanced Research, Collaboration, and Application Development Environment (ARCADE) is a test-bed maintained and operated by the Air Force to (1) serve as a centralized test-bed for all research and development activities related to JMS applications, including algorithm development, data source exposure, service orchestration, and software services, and provide developers reciprocal access to relevant tools and data to accelerate technology development, (2) allow the JMS program to communicate user capability priorities and requirements to developers, (3) provide the JMS program with access to state-of-the-art research, development, and computing capabilities, and (4) support JMS Program Office-led market research efforts by identifying outstanding performers that are available to shepherd into the formal transition process. In this paper we will share with the international remote sensing community some of the recent JMS and ARCADE developments that may contribute to greater SSA at the JSpOC in the future, and share technical areas still in great need.

  14. Advanced Cancer Detection Center

    DTIC Science & Technology

    2000-10-01

    projects have begun to lead to peer-reviewed extramural funding. In the case of the genistein and lycopene trials, ACDC funding has led to randomized...Unsafe Herbs Lycopene Supplements Associated with Illness or Milk Thistle Injury PC-SPES Drug/Nutrient/Supplement Interactions Prickly Ash Herbs

  15. Advanced Cancer Detection Center

    DTIC Science & Technology

    2009-01-01

    patient reported outcomes. The technology that makes this possible is a PC card that accepts tone-dial (push-button) sounds and can playback pre- recorded ...then be recorded : The video resolution is adequate for many clinical applications. While not precise enough for pathological diagnosis, it is...appropriate samples at frequent intervals. State-of-the-art techniques must be used for sensitive and specific detection of candidate infectious

  16. Advanced Cancer Detection Center

    DTIC Science & Technology

    2007-10-01

    Cancer Treatment Affecting the Central Nervous System (HLMCC 0707) • Melatonin and sleep hygiene for the treatment of insomnia following cancer...Determinants of Diabetes in the Young. (PI: Jeffrey Krischer, Ph.D.) Moffitt Community Clinical Oncology Program Research Base (PI: Jeffrey Krischer

  17. Advanced Materials Center, Battelle

    NASA Technical Reports Server (NTRS)

    Bellis, Harold

    1991-01-01

    The goal of the Mixed Oxide Program is to determine the results obtained by using microgravity processing on a commercially significant catalyst - V-P-O System. The topics are presented in viewgraph form and include the following: (1) reasons for using microgravity; (2) the synthesis process; (3) novel results of the earth based program; and (4) Dupont interests.

  18. Advanced Subsonic Combustion Rig

    NASA Technical Reports Server (NTRS)

    Lee, Chi-Ming

    1998-01-01

    Researchers from the NASA Lewis Research Center have obtained the first combustion/emissions data under extreme future engine operating conditions. In Lewis' new world-class 60-atm combustor research facility--the Advanced Subsonic Combustion Rig (ASCR)--a flametube was used to conduct combustion experiments in environments as extreme as 900 psia and 3400 F. The greatest challenge for combustion researchers is the uncertainty of the effects of pressure on the formation of nitrogen oxides (NOx). Consequently, U.S. engine manufacturers are using these data to guide their future combustor designs. The flametube's metal housing has an inside diameter of 12 in. and a length of 10.5 in. The flametube can be used with a variety of different flow paths. Each flow path is lined with a high-temperature, castable refractory material (alumina) to minimize heat loss. Upstream of the flametube is the injector section, which has an inside diameter of 13 in. and a length of 0.5-in. It was designed to provide for quick changeovers. This flametube is being used to provide all U.S. engine manufacturers early assessments of advanced combustion concepts at full power conditions prior to engine production. To date, seven concepts from engine manufacturers have been evaluated and improved. This collaborated development can potentially give U.S. engine manufacturers the competitive advantage of being first in the market with advanced low-emission technologies.

  19. Space Optic Manufacturing - X-ray Mirror

    NASA Technical Reports Server (NTRS)

    1998-01-01

    NASA's Space Optics Manufacturing Center has been working to expand our view of the universe via sophisticated new telescopes. The Optics Center's goal is to develop low-cost, advanced space optics technologies for the NASA program in the 21st century - including the long-term goal of imaging Earth-like planets in distant solar systems. To reduce the cost of mirror fabrication, Marshall Space Flight Center (MSFC) has developed replication techniques, the machinery and materials to replicate electro-formed nickel mirrors. The process allows fabricating precisely shaped mandrels to be used and reused as masters for replicating high-quality mirrors. This image shows a lightweight replicated x-ray mirror with gold coatings applied.

  20. Composites Manufacturing Education and Technology Facility Expedites Manufacturing Innovation

    SciTech Connect

    2017-01-01

    The Composites Manufacturing Education and Technology facility (CoMET) at the National Wind Technology Center at the National Renewable Energy Laboratory (NREL) paves the way for innovative wind turbine components and accelerated manufacturing. Available for use by industry partners and university researchers, the 10,000-square-foot facility expands NREL's composite manufacturing research capabilities by enabling researchers to design, prototype, and test composite wind turbine blades and other components -- and then manufacture them onsite. Designed to work in conjunction with NREL's design, analysis, and structural testing capabilities, the CoMET facility expedites manufacturing innovation.

  1. Human-centered design (HCD) of a fault-finding application for mobile devices and its impact on the reduction of time in fault diagnosis in the manufacturing industry.

    PubMed

    Kluge, Annette; Termer, Anatoli

    2017-03-01

    The present article describes the design process of a fault-finding application for mobile devices, which was built to support workers' performance by guiding them through a systematic strategy to stay focused during a fault-finding process. In collaboration with a project partner in the manufacturing industry, a fault diagnosis application was conceptualized based on a human-centered design approach (ISO 9241-210:2010). A field study with 42 maintenance workers was conducted for the purpose of evaluating the performance enhancement of fault finding in three different scenarios as well as for assessing the workers' acceptance of the technology. Workers using the mobile device application were twice as fast at fault finding as the control group without the application and perceived the application as very useful. The results indicate a vast potential of the mobile application for fault diagnosis in contemporary manufacturing systems.

  2. Integrated Manufacturing for Advanced MEAs

    SciTech Connect

    Emory S. De Castro; Yu-Min Tsou; Mark G. Roelofs; Olga Polevaya

    2007-03-30

    This program addressed a two-pronged goal for developing fuel cell components: lowering of precious metal content in membrane electrode assemblies (MEAs), thereby reducing the fuel cell cost, and creating MEAs that can operate at 120oC and 25% RH whereby the system efficiency and effectiveness is greatly improved. In completing this program, we have demonstrated a significant reduction in precious metal while at the same time increasing the power output (achieved 2005 goal of 0.6g/Kw). We have also identified a technology that allows for one step fabrication of MEAs and appears to be a feasible path toward achieving DOE’s 2010 targets for precious metal and power (approaches 0.2g/Kw). Our team partner Du Pont invented a new class of polymer electrolyte membrane that has sufficient stability and conductivity to demonstrate feasibility for operation at 120 oC and low relative humidity. Through the course of this project, the public has benefited greatly from numerous presentations and publications on the technical understanding necessary to achieve these goals.

  3. Custom Machines Advance Composite Manufacturing

    NASA Technical Reports Server (NTRS)

    2012-01-01

    Here is a brief list of materials that NASA will not be using to construct spacecraft: wood, adobe, fiberglass, bone. While it might be obvious why these materials would not make for safe space travel, they do share a common characteristic with materials that may well be the future foundation of spacecraft design: They all are composites. Formed of two or more unlike materials - such as cellulose and lignin in the case of wood, or glass fibers and plastic resin in the case of fiberglass-composites provide enhanced mechanical and physical properties through the combination of their constituent materials. For this reason, composites are used in everything from buildings, bathtubs, and countertops to boats, racecars, and sports equipment. NASA continually works to develop new materials to enable future space missions - lighter, less expensive materials that can still withstand the extreme demands of space travel. Composites such as carbon fiber materials offer promising solutions in this regard, providing strength and stiffness comparable to metals like aluminum but with less weight, allowing for benefits like better fuel efficiency and simpler propulsion system design. Composites can also be made fatigue tolerant and thermally stable - useful in space where temperatures can swing hundreds of degrees. NASA has recently explored the use of composites for aerospace applications through projects like the Composite Crew Module (CCM), a composite-constructed version of the aluminum-lithium Multipurpose Crew Capsule. The CCM was designed to give NASA engineers a chance to gain valuable experience developing and testing composite aerospace structures.

  4. An Advanced Telereflexive Tactical Response Robot

    DTIC Science & Technology

    2001-01-01

    Autonomous Robots 1 1 ,3947 ,2001 @ 2001 Kluwer Academic Publishers. Manufactured in The Netherlands. An Advanced Telereflexive Tactical Response... Robot H.R. EVERETT, G.A. GILBREATH AND D.A. CICCIMARO SPAWAR Systems Center*, San Diego, Code D371, 53406 Woodward Road, San Diego, CA 92152-7383...centered mapping” strategy. Keywords: robotic sensors, tactical response robot robotics , teleoperated, telereflexive, non-lethal response, world modeling

  5. Toward Advanced Nursing Practice along with People-Centered Care Partnership Model for Sustainable Universal Health Coverage and Universal Access to Health 1

    PubMed Central

    Kamei, Tomoko; Takahashi, Keiko; Omori, Junko; Arimori, Naoko; Hishinuma, Michiko; Asahara, Kiyomi; Shimpuku, Yoko; Ohashi, Kumiko; Tashiro, Junko

    2017-01-01

    ABSTRACT Objective: this study developed a people-centered care (PCC) partnership model for the aging society to address the challenges of social changes affecting people’s health and the new role of advanced practice nurses to sustain universal health coverage. Method: a people-centered care partnership model was developed on the basis of qualitative meta-synthesis of the literature and assessment of 14 related projects. The ongoing projects resulted in individual and social transformation by improving community health literacy and behaviors using people-centered care and enhancing partnership between healthcare providers and community members through advanced practice nurses. Results: people-centered care starts when community members and healthcare providers foreground health and social issues among community members and families. This model tackles these issues, creating new values concerning health and forming a social system that improves quality of life and social support to sustain universal health care through the process of building partnership with communities. Conclusion: a PCC partnership model addresses the challenges of social changes affecting general health and the new role of advanced practice nurses in sustaining UHC. PMID:28146179

  6. Boosting Manufacturing through Modular Chemical Process Intensification

    SciTech Connect

    2016-12-09

    Manufacturing USA's Rapid Advancement in Process Intensification Deployment Institute will focus on developing breakthrough technologies to boost domestic energy productivity and energy efficiency by 20 percent in five years through manufacturing processes.

  7. Boosting Manufacturing through Modular Chemical Process Intensification

    ScienceCinema

    None

    2017-01-06

    Manufacturing USA's Rapid Advancement in Process Intensification Deployment Institute will focus on developing breakthrough technologies to boost domestic energy productivity and energy efficiency by 20 percent in five years through manufacturing processes.

  8. Program for establishing long-time flight service performance of composite materials in the center wing structure of C-130 aircraft. Phase 1: Advanced development

    NASA Technical Reports Server (NTRS)

    Harvill, W. E.; Kays, A. O.; Young, E. C.; Mcgee, W. M.

    1972-01-01

    Areas where selective reinforcement of conventional metallic structure can improve static strength/fatigue endurance at lower weight than would be possible if metal reinforcement were used are discussed. These advantages are now being demonstrated by design, fabrication, and tests of three boron-epoxy reinforced C-130E center wing boxes. This structural component was previously redesigned using an aluminum build-up to meet increased severity of fatigue loadings. Direct comparisons of relative structural weights, manufacturing costs, and producibility can therefore be obtained, and the long-time flight service performance of the composite reinforced structure can be evaluated against the wide background of metal reinforced structure.

  9. Introduction of laser initiation for the 48-inch Advanced Solid Rocket Motor (ASRM) test motors at Marshall Space Flight Center (MSFC)

    NASA Technical Reports Server (NTRS)

    Zimmerman, Chris J.; Litzinger, Gerald E.

    1993-01-01

    The Advanced Solid Rocket Motor is a new design for the Space Shuttle Solid Rocket Booster. The new design will provide more thrust and more payload capability, as well as incorporating many design improvements in all facets of the design and manufacturing process. A 48-inch (diameter) test motor program is part of the ASRM development program. This program has multiple purposes for testing of propellent, insulation, nozzle characteristics, etc. An overview of the evolution of the 48-inch ASRM test motor ignition system which culminated with the implementation of a laser ignition system is presented. The laser system requirements, development, and operation configuration are reviewed in detail.

  10. FAmily CEntered (FACE) advance care planning: Study design and methods for a patient-centered communication and decision-making intervention for patients with HIV/AIDS and their surrogate decision-makers.

    PubMed

    Kimmel, Allison L; Wang, Jichuan; Scott, Rachel K; Briggs, Linda; Lyon, Maureen E

    2015-07-01

    Although the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has become a chronic illness, disease-specific advance care planning has not yet been evaluated for the palliative care needs of adults with HIV/AIDS. This prospective, longitudinal, randomized, two-arm controlled clinical trial aims to test the efficacy of FAmily CEntered advance care planning among adults living with AIDS and/or HIV with co-morbidities on congruence in treatment preferences, healthcare utilization, and quality of life. The FAmily CEntered intervention arm is two face-to-face sessions with a trained, certified facilitator: Session 1) Disease-Specific Advance Care Planning Respecting Choices Interview; Session 2) Completion of advance directive. The Healthy Living Control arm is: Session 1) Developmental/Relationship History; Session 2) Nutrition. Follow-up data will be collected at 3, 6, 12, and 18 months post-intervention. A total of 288 patient/surrogate dyads will be enrolled from five hospital-based, out-patient clinics in Washington, District of Columbia. Participants will be HIV positive and ≥ 21 years of age; surrogates will be ≥ 18 years of age. Exclusion criteria are homicidality, suicidality, psychosis, and impaired cognitive functioning. We hypothesize that this intervention will enhance patient-centered communication with a surrogate decision-maker about end of life treatment preferences over time, enhance patient quality of life and decrease health care utilization. We further hypothesize that this intervention will decrease health disparities for Blacks in completion of advance directives. If proposed aims are achieved, the benefits of palliative care, particularly increased treatment preferences about end-of-life care and enhanced quality of life, will be extended to people living with AIDS.

  11. Manufacturing methods of testing the large-sized optics at the stage of grinding, aspherical surface centering, and interface elements positioning before gluing

    NASA Astrophysics Data System (ADS)

    Semenov, Aleksandr P.; Abdulkadyrov, Magomed A.; Patrikeev, Vladimir E.

    2016-07-01

    The article describes the method of testing the absolute profile of large-sized astronomical mirrors grinded aspherical surface and the method of test the aspherical surface decentering relative to the astronomical mirror geometrical center by means of a linear three-point spherometer, which is subsequently moved perpendicular to the direction from the optical surface center to the edge, as well as the method of positioning the interface elements being glued.

  12. NASA University Research Centers Technical Advances in Aeronautics, Space Sciences and Technology, Earth Systems Sciences, Global Hydrology, and Education. Volumes 2 and 3

    NASA Technical Reports Server (NTRS)

    Coleman, Tommy L. (Editor); White, Bettie (Editor); Goodman, Steven (Editor); Sakimoto, P. (Editor); Randolph, Lynwood (Editor); Rickman, Doug (Editor)

    1998-01-01

    This volume chronicles the proceedings of the 1998 NASA University Research Centers Technical Conference (URC-TC '98), held on February 22-25, 1998, in Huntsville, Alabama. The University Research Centers (URCS) are multidisciplinary research units established by NASA at 11 Historically Black Colleges or Universities (HBCU's) and 3 Other Minority Universities (OMU's) to conduct research work in areas of interest to NASA. The URC Technical Conferences bring together the faculty members and students from the URC's with representatives from other universities, NASA, and the aerospace industry to discuss recent advances in their fields.

  13. Cable manufacture

    NASA Technical Reports Server (NTRS)

    Gamble, P.

    1972-01-01

    A survey is presented of flat electrical cable manufacturing, with particular reference to patented processes. The economics of manufacture based on an analysis of material and operating costs is considered for the various methods. Attention is given to the competitive advantages of the several processes and their resulting products. The historical area of flat cable manufacture is presented to give a frame of reference for the survey.

  14. Training for New Manufacturing Technologies.

    ERIC Educational Resources Information Center

    Jacobs, James

    1988-01-01

    Examines the effects of computer-based manufacturing technologies on employment opportunities and job skills. Describes the establishment of the Industrial Technology Institute in Michigan to develop and utilize advanced manufacturing technologies, and the institute's relationship to the state's community colleges. Reviews lessons learned from…

  15. Robotic welding at the Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Jones, Clyde S.

    1992-01-01

    The Marshall Space Flight Center is developing welding and robotics technologies to improve manufacturing of space hardware. Commercial robots are used for these development programs, but they are teamed with advanced sensors, process controls, and computer simulation to form highly productive manufacturing systems. Application of welding robotics and controls to structural welding for the space shuttle and space station Freedom programs is addressed. Several advanced welding process sensors under development for application to space hardware are discussed, as well as the application of commercial robotic simulation software to provide offline programming.

  16. Rapid response manufacturing (RRM). Final CRADA report

    SciTech Connect

    Cain, W.D.; Waddell, W.L.

    1998-02-10

    US industry is fighting to maintain its competitive edge in the global market place. Markets fluctuate rapidly. Companies have to be able to respond quickly with improved, high quality, cost efficient products. Because companies and their suppliers are geographically distributed, rapid product realization is dependent on the development of a secure integrated concurrent engineering environment operating across multiple business entities. The way products are developed and brought to market can be improved and made more efficient through the proper incorporation of emerging technologies implemented in a secure environment. This documents the work done under this CRADA to develop capabilities, which permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process. Lockheed Martin Energy Systems (LMES), through a CRADA with the National Center for Manufacturing Sciences (NCMS), worked within a consortium of major industrial firms--Ford, General Motors, Texas Instruments, United Technologies, and Eastman Kodak--and several small suppliers of advanced manufacturing technology--MacNeal-Schwendler Corp., Teknowledge Corp., Cimplex Corp., Concentra, Spatial Technology, and Structural Dynamics Research Corp. (SDRC)--to create infrastructure to support the development and implementation of secure engineering environments for Rapid Response Manufacturing. The major accomplishment achieved under this CRADA was the demonstration of a prototypical implementation of a broad-based generic framework for automating and integrating the design-to-manufacturing activities associated with machined parts in a secure NWC compliant environment. Specifically, methods needed to permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process were developed and demonstrated. An important aspect of this demonstration was

  17. 77 FR 26743 - The Manufacturing Council: Work Session of the Manufacturing Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... International Trade Administration The Manufacturing Council: Work Session of the Manufacturing Council AGENCY...: This notice sets forth the schedule and agenda for an open work session of the Manufacturing Council... Freescale Austin Technology and Manufacturing Center, 3501 Ed Bluestein Boulevard, Austin, Texas. All...

  18. Manufacturing Technology.

    ERIC Educational Resources Information Center

    Barnes, James L.

    This curriculum guide is designed to assist junior high school industrial arts teachers in planning new courses and revising existing courses in manufacturing technology. Addressed in the individual units of the guide are the following topics: introduction to manufacturing, materials processing, personnel management, production management,…

  19. Additive Manufacturing Infrared Inspection

    NASA Technical Reports Server (NTRS)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  20. Benchmarks of Global Clean Energy Manufacturing

    SciTech Connect

    Sandor, Debra; Chung, Donald; Keyser, David; Mann, Margaret; Engel-Cox, Jill

    2017-01-01

    The Clean Energy Manufacturing Analysis Center (CEMAC), sponsored by the U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE), provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Benchmarks of Global Clean Energy Manufacturing sheds light on several fundamental questions about the global clean technology manufacturing enterprise: How does clean energy technology manufacturing impact national economies? What are the economic opportunities across the manufacturing supply chain? What are the global dynamics of clean energy technology manufacturing?

  1. ATS materials/manufacturing

    SciTech Connect

    Karnitz, M.A.; Wright, I.G.; Ferber, M.K.

    1997-11-01

    The Materials/Manufacturing Technology subelement is a part of the base technology portion of the Advanced Turbine Systems (ATS) Program. The work in this subelement is being performed predominantly by industry with assistance from national laboratories and universities. The projects in this subelement are aimed toward hastening the incorporation of new materials and components in gas turbines. Work is currently ongoing on thermal barrier coatings (TBCs), the scale-up of single crystal airfoil manufacturing technologies, materials characterization, and technology information exchange. This paper presents highlights of the activities during the past year. 12 refs., 24 figs., 4 tabs.

  2. Computers in manufacturing.

    PubMed

    Hudson, C A

    1982-02-12

    Computers are now widely used in product design and in automation of selected areas in factories. Within the next decade, the use of computers in the entire spectrum of manufacturing applications, from computer-aided design to computer-aided manufacturing and robotics, is expected to be practical and economically justified. Such widespread use of computers on the factory floor awaits further advances in computer capabilities, the emergence of systems that are adaptive to the workplace, and the development of interfaces to link islands of automation and to allow effective user communications.

  3. Operation of the power information center: Performance of secretariat functions and information exchange activities in the advanced power field of the interagency advanced power group

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Highlights of activities conducted during the reporting period to facilitate the exchange of technical information among scientists and engineers both within the federal government and within industry are cited. Interagency Advanced Power Group meetings and special efforts, project briefs, and organization development are considered.

  4. Wireless technology for integrated manufacturing

    SciTech Connect

    Manges, W.W.; Allgood, G.O.; Shourbaji, A.A.

    1996-08-01

    This paper describes the ground breaking work in Oak Ridge facilities that now leads us to the brink of the wireless revolution in manufacturing. The focus is on solving tough technological problems necessary for success and addressing the critical issues of throughput, security, reliability, and robustness in applying wireless technology to manufacturing processes. Innovative solutions to these problems are highlighted through detailed designs and testbed implementations that demonstrate key concepts. The DOE-Oak Ridge complex represented by the Oak Ridge Centers for Manufacturing Technologies (ORCMT) continues to develop these technologies and will continue to focus on solving tough manufacturing problems.

  5. Analysis of the confluence of three patterns using the Centering and Pointing System (CAPS) images for the Advanced Radiographic Capability (ARC) at the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Leach, Richard R.; Awwal, Abdul; Bliss, Erlan; Roberts, Randy; Rushford, Michael; Wilhelmsen, Karl; Zobrist, Thomas

    2014-09-01

    The Advance Radiographic Capability (ARC) at the National Ignition Facility (NIF) is a laser system that employs up to four petawatt (PW) lasers to produce a sequence of short pulses that generate X-rays which backlight highdensity internal confinement fusion (ICF) targets. Employing up to eight backlighters, ARC can produce an X-ray "motion picture" to diagnose the compression and ignition of a cryogenic deuterium-tritium target with tens-ofpicosecond temporal resolution during the critical phases of an ICF shot. Multi-frame, hard-X-ray radiography of imploding NIF capsules is a capability which is critical to the success of NIF's missions. The function of the Centering and Pointing System (CAPS) in ARC is to provide superimposed near-field and far-field images on a common optical path. The Images are then analyzed to extract beam centering and pointing data for the control system. The images contain the confluence of pointing, centering, and reference patterns. The patterns may have uneven illumination, particularly when the laser is misaligned. In addition, the simultaneous appearance of three reference patterns may be co-incidental, possibly masking one or more of the patterns. Image analysis algorithms have been developed to determine the centering and pointing position of ARC from these images. In the paper we describe the image analysis algorithms used to detect and identify the centers of these patterns. Results are provided, illustrating how well the process meets system requirements.

  6. Materials Characterization of Additively Manufactured Components for Rocket Propulsion

    NASA Technical Reports Server (NTRS)

    Carter, Robert; Draper, Susan; Locci, Ivan; Lerch, Bradley; Ellis, David; Senick, Paul; Meyer, Michael; Free, James; Cooper, Ken; Jones, Zachary

    2015-01-01

    To advance Additive Manufacturing (AM) technologies for production of rocket propulsion components the NASA Glenn Research Center (GRC) is applying state of the art characterization techniques to interrogate microstructure and mechanical properties of AM materials and components at various steps in their processing. The materials being investigated for upper stage rocket engines include titanium, copper, and nickel alloys. Additive manufacturing processes include laser powder bed, electron beam powder bed, and electron beam wire fed processes. Various post build thermal treatments, including Hot Isostatic Pressure (HIP), have been studied to understand their influence on microstructure, mechanical properties, and build density. Micro-computed tomography, electron microscopy, and mechanical testing in relevant temperature environments has been performed to develop relationships between build quality, microstructure, and mechanical performance at temperature. A summary of GRC's Additive Manufacturing roles and experimental findings will be presented.

  7. Material Characterization of Additively Manufactured Components for Rocket Propulsion

    NASA Technical Reports Server (NTRS)

    Carter, Robert; Draper, Susan; Locci, Ivan; Lerch, Bradley; Ellis, David; Senick, Paul; Meyer, Michael; Free, James; Cooper, Ken; Jones, Zachary

    2015-01-01

    To advance Additive Manufacturing (AM) technologies for production of rocket propulsion components the NASA Glenn Research Center (GRC) is applying state of the art characterization techniques to interrogate microstructure and mechanical properties of AM materials and components at various steps in their processing. The materials being investigated for upper stage rocket engines include titanium, copper, and nickel alloys. Additive manufacturing processes include laser powder bed, electron beam powder bed, and electron beam wire fed processes. Various post build thermal treatments, including Hot Isostatic Pressure (HIP), have been studied to understand their influence on microstructure, mechanical properties, and build density. Micro-computed tomography, electron microscopy, and mechanical testing in relevant temperature environments has been performed to develop relationships between build quality, microstructure, and mechanical performance at temperature. A summary of GRCs Additive Manufacturing roles and experimental findings will be presented.

  8. 75 FR 6355 - Manufacturing Extension Partnership (MEP) Availability of Funds for Three Regions Including the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... projects will establish manufacturing extension centers under the Manufacturing Extension Partnership... National Institute of Standards and Technology Manufacturing Extension Partnership (MEP) Availability of... qualified organizations for funding projects that provide manufacturing extension services to...

  9. Smart Manufacturing.

    PubMed

    Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

    2015-01-01

    Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing.

  10. Public health assessment for Joslyn Manufacturing and Supply Company, Brooklyn Center, Hennepin County, Minnesota, Region 5. Cerclis No. MND044799856. Final report

    SciTech Connect

    Not Available

    1994-02-07

    The Joslyn Manufacturing and Supply Company site is listed by the U.S. Environmental Protection Agency (EPA) on the National Priorities List (NPL). Wood-preserving operations were conducted at the site from the 1920's until 1980. Process wastes containing creosote, pentachlorophenol (PCP), and copper/chromium/arsenic (CCA) were disposed in two on-site waste ponds. In addition, burial of wastes and at least two large spills of wood treating solutions also occurred during the history of site operations. Groundwater and soil at the site are contaminated with polynuclear aromatic hydrocarbons (PAHs), and with pentachlorophenol (PCP). Polychlorinated dioxins and furans, common contaminants of PCP, have also been detected in soils and groundwater in the area of heaviest PCP contamination. Individuals working with contaminated soil on the site may be exposed to PAHs and PCP via dermal contact with contaminated soil, or via inhalation or ingestion of contaminated soil or dusts. Persons within a building on-site that houses equipment associated with the pump-out system could inhale contaminants volatilized from extracted groundwater or free product.

  11. Coordinated Research in Robotics and Integrated Manufacturing.

    DTIC Science & Technology

    1983-07-31

    of top rate senior people. Dur- ing the first annual contract period eight new faculty were brought to the College in robotics and manufacturing ...The University of Michigan College of Engineering COORDINATED RESEARCH IN ROBOTICS AND INTEGRATED MANUFACTURING FIRST...ANNUAL REPORT ON COORDINATED RESEARCH IN ROBOTICS AND INTEGRATED MANUFACTURING THE UNIVERSITY OF MICHIGAN Background The Center for Robotics and

  12. Advancing survivorship care through the National Cancer Survivorship Resource Center: developing American Cancer Society guidelines for primary care providers.

    PubMed

    Cowens-Alvarado, Rebecca; Sharpe, Katherine; Pratt-Chapman, Mandi; Willis, Anne; Gansler, Ted; Ganz, Patricia A; Edge, Stephen B; McCabe, Mary S; Stein, Kevin

    2013-05-01

    The National Cancer Survivorship Resource Center (The Survivorship Center) began in 2010 as a collaboration between the American Cancer Society and the George Washington University Cancer Institute and was funded by the Centers for Disease Control and Prevention. The Survivorship Center aims to improve the overall health and quality of life of posttreatment cancer survivors. One key to addressing the needs of this ever-growing population is to develop clinical follow-up care guidelines that emphasize not only the importance of surveillance for cancer recurrence, but also address the assessment and management of the physical and psychosocial long-term and late effects that may result from having cancer and undergoing cancer treatment as well as highlight the importance of healthy behaviors that can reduce the risk of cancer recurrence, second primary cancers, and other chronic diseases. Currently, The Survivorship Center is coordinating the work of experts in oncology, primary care, and other health care professions to develop follow-up care guidelines for 10 priority cancer sites.

  13. Rapid response manufacturing (RRM)

    SciTech Connect

    Cain, W.D.; Waddell, W.L.

    1997-02-18

    US industry is fighting to maintain its competitive edge in the global market place. Today markets fluctuate rapidly. Companies, to survive, have to be able to respond with quick-to-market, improved, high quality, cost efficient products. The way products are developed and brought to market can be improved and made more efficient through the proper incorporation of emerging technologies. The RRM project was established to leverage the expertise and resources of US private industries and federal agencies to develop, integrate, and deploy new technologies that meet critical needs for effective product realization. The RRM program addressed a needed change in the US Manufacturing infrastructure that will ensure US competitiveness in world market typified by mass customization. This project provided the effort needed to define, develop and establish a customizable infrastructure for rapid response product development design and manufacturing. A major project achievement was the development of a broad-based framework for automating and integrating the product and process design and manufacturing activities involved with machined parts. This was accomplished by coordinating and extending the application of feature-based product modeling, knowledge-based systems, integrated data management, and direct manufacturing technologies in a cooperative integrated computing environment. Key technological advancements include a product model that integrates product and process data in a consistent, minimally redundant manner, an advanced computer-aided engineering environment, knowledge-based software aids for design and process planning, and new production technologies to make products directly from design application software.

  14. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS).

    PubMed

    Shamoon, Harry; Center, David; Davis, Pamela; Tuchman, Mendel; Ginsberg, Henry; Califf, Robert; Stephens, David; Mellman, Thomas; Verbalis, Joseph; Nadler, Lee; Shekhar, Anantha; Ford, Daniel; Rizza, Robert; Shaker, Reza; Brady, Kathleen; Murphy, Barbara; Cronstein, Bruce; Hochman, Judith; Greenland, Philip; Orwoll, Eric; Sinoway, Lawrence; Greenberg, Harry; Jackson, Rebecca; Coller, Barry; Topol, Eric; Guay-Woodford, Lisa; Runge, Marschall; Clark, Robert; McClain, Don; Selker, Harry; Lowery, Curtis; Dubinett, Steven; Berglund, Lars; Cooper, Dan; Firestein, Gary; Johnston, S Clay; Solway, Julian; Heubi, James; Sokol, Ronald; Nelson, David; Tobacman, Larry; Rosenthal, Gary; Aaronson, Lauren; Barohn, Richard; Kern, Philip; Sullivan, John; Shanley, Thomas; Blazar, Bruce; Larson, Richard; FitzGerald, Garret; Reis, Steven; Pearson, Thomas; Buchanan, Thomas; McPherson, David; Brasier, Allan; Toto, Robert; Disis, Mary; Drezner, Marc; Bernard, Gordon; Clore, John; Evanoff, Bradley; Imperato-McGinley, Julianne; Sherwin, Robert; Pulley, Jill

    2012-04-01

    The formation of the National Center for Advancing Translational Sciences (NCATS) brings new promise for moving basic science discoveries to clinical practice, ultimately improving the health of the nation. The Clinical and Translational Science Award (CTSA) sites, now housed with NCATS, are organized and prepared to support in this endeavor. The CTSAs provide a foundation for capitalizing on such promise through provision of a disease-agnostic infrastructure devoted to clinical and translational (C&T) science, maintenance of training programs designed for C&T investigators of the future, by incentivizing institutional reorganization and by cultivating institutional support.

  15. An evaluation of the total quality management implementation strategy for the advanced solid rocket motor project at NASA's Marshall Space Flight Center. M.S. Thesis - Tennessee Univ.

    NASA Technical Reports Server (NTRS)

    Schramm, Harry F.; Sullivan, Kenneth W.

    1991-01-01

    An evaluation of the NASA's Marshall Space Flight Center (MSFC) strategy to implement Total Quality Management (TQM) in the Advanced Solid Rocket Motor (ASRM) Project is presented. The evaluation of the implementation strategy reflected the Civil Service personnel perspective at the project level. The external and internal environments at MSFC were analyzed for their effects on the ASRM TQM strategy. Organizational forms, cultures, management systems, problem solving techniques, and training were assessed for their influence on the implementation strategy. The influence of ASRM's effort was assessed relative to its impact on mature projects as well as future projects at MSFC.

  16. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS)

    PubMed Central

    Bernard, Gordon R.

    2012-01-01

    The formation of the National Center for Advancing Translational Sciences (NCATS) brings new promise for moving basic and discoveries to clinical practice, ultimately improving the health of the nation. The CTSA sites, now housed with NCATS, are organized and prepared to support in this endeavor. The CTSAs provide a foundation for capitalizing on such promise through provision of a disease-agnostic infrastructure devoted to C&T science, maintenance of training programs designed for C&T investigators of the future, by incentivizing institutional reorganization and by cultivating institutional support. PMID:22507116

  17. Factors Associated with Advanced Inferior Vena Cava Filter Removals: A Single-Center Retrospective Study of 203 Patients Over 7 Years

    SciTech Connect

    Dowell, Joshua D. Wagner, Daniel Elliott, Eric; Yildiz, Vedat O. Pan, Xueliang

    2016-02-15

    PurposeTo identify factors associated with advanced inferior vena cava filter (IVCF) retrieval to raise awareness on technical considerations, retrieval efficiency, and patient safety.Materials and MethodsA single-center retrospective review was performed of 203 consecutive retrievable IVC filters placed between 2007 and 2014. Attempted retrievals were classified as advanced if the routine “snare and sheath” technique was initially unsuccessful after multiple attempts, or an alternate endovascular maneuver or access site was utilized. Patient and filter characteristics were recorded.Results203 attempted retrievals were reviewed (48.7 % male, 51.2 % female, mean age 52.7 years, mean dwell time 109 days). Advanced retrievals were observed in 20 patients (9.8 %) (15 females, 5 males). Fluoroscopy time (p ≤ 0.01, 34.3 ± 21.1 and 5.3 ± 4.5 min for advanced retrievals and routine retrievals respectively, same below), gender (p = 0.031), and retrieval tilt angle (p ≤ 0.01, 5.7 ± 5.10° vs. 11.9 ± 11.03°) were associated with advanced retrievals. Females were 3.16 times more likely to have an advanced retrieval performed than males with a significantly higher tilt angle in those with advanced retrieval. History of cancer (p = 0.502), dwell time (p = 0.916), retrieval caval diameter (p = 0.053), placement caval diameter (p = 0.365), filter type (p = 0.710), strut perforation (p = 0.506), placement tilt angle (p = 0.311), and age (p = 0.558) were not found significantly associated with advanced retrievals.ConclusionsWomen are at increased risk for advanced filter retrieval secondary to a significant change in filter tilt over time compared to men, independent of filter type or competing demographic or filter risks, likely placing them at increased risk for higher procedural fluoroscopy times.

  18. Silver Editions II: Advancing the Concept of Library-Centered Humanities Programs for Older Adults. An Evaluation.

    ERIC Educational Resources Information Center

    Van Fleet, Connie; And Others

    This report is an evaluation of the Silver Edition II Project, a program to offer library-centered humanities programming to older adults. In the program local scholars in seven geographically dispersed library systems led discussion groups made up of 20 to 25 participating older adults. This evaluation focuses on the stated goals of the project:…

  19. A New Approach to Low-Wage Workers and Employers. Launching the Work Advancement and Support Center Demonstration

    ERIC Educational Resources Information Center

    Anderson, Jacquelyn; Kato, Linda Yuriko; Riccio, James A.; Blank, Susan

    2006-01-01

    Since 1998, federally funded One-Stop Service Centers around the country have focused primarily on assisting the unemployed into work. WASC tests a strategy that expands that mission by targeting people who are already working, but at low wages. Through career coaching, skills training, and better connections with employers - and led by a newly…

  20. The Student-Centered Classroom Made Real: Transforming Student Presentations in an Advanced Course on Technical German

    ERIC Educational Resources Information Center

    Rarick, Damon O.

    2010-01-01

    This article describes how the author has successfully combined polling with more traditional instructional strategies to enhance student presentation skills in an advanced course teaching technical German. By helping students select and prepare topics, anticipate questions and engage the audience, instructors can eliminate some of the root causes…

  1. History of Resistance Welding Oxide Dispersion Strengthened Cladding and other High Temperature Materials at Center for Advanced Energy Studies

    SciTech Connect

    Larry Zirker; Nathan Jerred; Dr. Indrajit Charit; James Cole

    2012-03-01

    Research proposal 08-1079, 'A Comparative Study of Welded ODS Cladding Materials for AFCI/GNEP,' was funded in 2008 under an Advanced Fuel Cycle Initiative (AFCI) Research and Development Funding Opportunity, number DE-PS07-08ID14906. Th proposal sought to conduct research on joining oxide dispersion strengthen (ODS) tubing material to a solid end plug. This document summarizes the scientific and technical progress achieved during the project, which ran from 2008 to 2011.

  2. Additive Manufacturing Integrated Energy Demonstration

    SciTech Connect

    Jackson, Roderick; Lee, Brian; Love, Lonnie; Mabe, Gavin; Keller, Martin; Curran, Scott; Chinthavali, Madhu; Green, Johney; Sawyer, Karma; Enquist, Phil

    2016-02-05

    Meet AMIE - the Additive Manufacturing Integrated Energy demonstration project. Led by Oak Ridge National Laboratory and many industry partners, the AMIE project changes the way we think about generating, storing, and using electrical power. AMIE uses an integrated energy system that shares energy between a building and a vehicle. And, utilizing advanced manufacturing and rapid innovation, it only took one year from concept to launch.

  3. Additive Manufacturing Integrated Energy Demonstration

    ScienceCinema

    Jackson, Roderick; Lee, Brian; Love, Lonnie; Mabe, Gavin; Keller, Martin; Curran, Scott; Chinthavali, Madhu; Green, Johney; Sawyer, Karma; Enquist, Phil

    2016-07-12

    Meet AMIE - the Additive Manufacturing Integrated Energy demonstration project. Led by Oak Ridge National Laboratory and many industry partners, the AMIE project changes the way we think about generating, storing, and using electrical power. AMIE uses an integrated energy system that shares energy between a building and a vehicle. And, utilizing advanced manufacturing and rapid innovation, it only took one year from concept to launch.

  4. Control Center Technology Conference Proceedings

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Conference papers and presentations are compiled and cover evolving architectures and technologies applicable to flight control centers. Advances by NASA Centers and the aerospace industry are presented.

  5. Composites Materials and Manufacturing Technologies for Space Applications

    NASA Technical Reports Server (NTRS)

    Vickers, J. H.; Tate, L. C.; Gaddis, S. W.; Neal, R. E.

    2016-01-01

    Composite materials offer significant advantages in space applications. Weight reduction is imperative for deep space systems. However, the pathway to deployment of composites alternatives is problematic. Improvements in the materials and processes are needed, and extensive testing is required to validate the performance, qualify the materials and processes, and certify components. Addressing these challenges could lead to the confident adoption of composites in space applications and provide spin-off technical capabilities for the aerospace and other industries. To address the issues associated with composites applications in space systems, NASA sponsored a Technical Interchange Meeting (TIM) entitled, "Composites Materials and Manufacturing Technologies for Space Applications," the proceedings of which are summarized in this Conference Publication. The NASA Space Technology Mission Directorate and the Game Changing Program chartered the meeting. The meeting was hosted by the National Center for Advanced Manufacturing (NCAM)-a public/private partnership between NASA, the State of Louisiana, Louisiana State University, industry, and academia, in association with the American Composites Manufacturers Association. The Louisiana Center for Manufacturing Sciences served as the coordinator for the TIM.

  6. Working with U.S. Manufacturers to Succeed in Global Markets (Poster)

    SciTech Connect

    Not Available

    2012-06-01

    Poster created for the Advanced Manufacturing Office to be used at meetings, presentations, and exhibits. The Advanced Manufacturing Office (AMO) fosters advanced manufacturing innovation, facilitates public and private partnerships, and drives rapid deployment of technologies to help manufacturers: Save energy and money, Reduce environmental impacts, Enhance workforce development, and Improve national energy security and competitiveness throughout the supply chain.

  7. A large, single-center, real-world study of clinicopathological characteristics and treatment in advanced ALK-positive non-small-cell lung cancer.

    PubMed

    Chen, Gang; Chen, Xi; Zhang, Yaxiong; Yan, Fang; Fang, Wenfeng; Yang, Yunpeng; Hong, Shaodong; Miao, Siyu; Wu, Manli; Huang, Xiaodan; Luo, Youli; Zhou, Cong; Gong, Run; Huang, Yan; Zhou, Ningning; Zhao, Hongyun; Zhang, Li

    2017-04-04

    Crizotinib has achieved astonishing success in advanced non-small-cell lung cancer (NSCLC) patients harboring anaplastic lymphoma kinase (ALK) rearrangement. However, no real-world studies described the clinicopathological characteristics and treatment of such patients in China. Patients were consecutively collected from Sun Yat-sen University Cancer Center. Chi-square test was applied to explore the relationship between ALK fusion status and metastasis sites. Kaplan-Meier methods and multivariable analyses were used to estimate progression-free survival (PFS). A total of 291 advanced NSCLC patients (ALK (+), N = 97; both ALK & epidermal growth factor receptor (EGFR) (-), N = 194) were enrolled. The occurrence of brain metastasis in ALK-positive patients was significantly higher than double-negative ones both at baseline (26.5% vs. 16.5%, P = 0.038) and during treatment (25.8% vs. 11.9%, P = 0.003), but opposite for pleural effusion (6.2% vs. 26.9%, P < 0.001 at baseline; 3.1% vs. 10.3%, P = 0.031 during treatment). ALK-positive patients of 53.6% used crizotinib, whereas others only received chemotherapy (37.1%) or supportive care (9.3%). Usage of crizotinib prolonged PFS compared with chemotherapy in ALK-positive patients (median PFS 17.6 m vs. 4.8 m, P < 0.001). ALK-positive NSCLC had more brain metastasis and less pleural effusion than double-negative ones. Crizotinib showed better PFS than chemotherapy in advanced ALK-positive NSCLC at any line. However, half advanced ALK-positive patients never received crizotinib, which was grim and need improving.

  8. Platinum-based Chemotherapy in Primary Advanced Seminoma—a Retrospective Analysis: Treatment Results at the Northern Israel Oncology Center (1989–2010)

    PubMed Central

    Stein, Moshe E.; Drumea, Karen; Charas, Tomer; Gershuny, Anthony; Ben-Yosef, Rahamim

    2014-01-01

    Objective: Over the past 30 years, great strides have been made in the treatment of disseminated testicular tumors. Despite the low number of patients and the rarity of studies concerning primary advanced seminoma, the efficacy of chemotherapy is clear, mainly 3–4-cisplatin-based chemotherapy. Aiming to contribute to the understanding and implementation of proper chemotherapeutic management in advanced seminoma patients, we retrospectively summarized our experience with 26 patients who were referred for platinum-based chemotherapy, post-orchiectomy to the Northern Israel Oncology Center between 1989 and 2010. Response rate, side effects, and long-term outcome were investigated. Methods: Before chemotherapy, meticulous staging was done, including tumor markers (B-human chorionic gonadotropin (B-HCG), alpha-fetoprotein (AFP), and lactic dehydrogenase (LDH)), and abdominal and pelvic computerized tomography (CT) scans were carried out. Results: All 26 treated patients achieved complete remission, clinically and symptomatically, with normalization of their CT scans. At a median follow-up of 120 months (range, 24–268 months) all patients are alive, without evidence of recurrent disease. One patient whose disease recurred twice achieved a third complete remission following salvage treatment with high-dose chemotherapy and autologous peripheral stem cell transplantation. Another patient, who preferred surveillance, relapsed abdominally after 9 months but achieved long-standing complete remission with cisplatin-based chemotherapy. Both these patients are alive with no evidence of disease. Three patients recovered uneventfully from bleomycin-induced pneumonitis. Conclusions: Advanced seminoma is a highly curable disease using platinum-based chemotherapy. Our study confirms the efficacy and safety of cisplatin-based chemotherapy in the treatment of advanced seminoma. PMID:24498512

  9. Communication About Sexuality in Advanced Illness Aligns With a Palliative Care Approach to Patient-Centered Care.

    PubMed

    Leung, Margaret W; Goldfarb, Shari; Dizon, Don S

    2016-02-01

    Treatment-related sexual complications are common in cancer patients although rarely discussed in the palliative care setting. Sexuality is an important survivorship issue and remains relevant even in the terminal setting. There are multiple barriers in dialoguing about intimacy and sexual functioning from the patient and provider perspectives. Palliative care providers, while not expected to be sexual health experts, can provide comprehensive patient-centered care by including sexual health as part of their evaluation. They can explore how sexual dysfunction can impair functioning and utilize an interdisciplinary approach to manage symptoms. Palliative care providers can help patients identify their goals of care and explore what anticipated sexual changes and treat-related side effects are tolerable and intolerable to the patient's quality of life. Principles on addressing sexuality in the palliative setting and practical ways of incorporating sexual history into the palliative care assessment are provided.

  10. Final Report for The University of Texas at Arlington Optical Medical Imaging Section of Advanced Imaging Research Center

    SciTech Connect

    Khosrow Behbehani

    2013-02-26

    The goal of this project was to create state-of-the-art optical medical imaging laboratories for the Biomedical Engineering faculty and student researchers of the University of Texas at Arlington (UTA) on the campus of the University of Texas Southwestern Medical Center (UTSW). This has been successfully achieved. These laboratories provide an unprecedented opportunity for the bioengineers (from UTA) to bring about new breakthroughs in medical imaging using optics. Specifically, three major laboratories have been successfully established and state-of-the-art scientific instruments have been placed in the labs. As a result of this grant, numerous journal and conference publications have been generated, patents for new inventions have been filed and received, and many additional grants for the continuation of the research has been received.

  11. Developing partnerships to advance youth violence prevention in Puerto Rico: the role of an academic center of excellence.

    PubMed

    Mirabal, Brenda; López-Sánchez, Gerardo; Franco-Ortiz, Mariluz; Méndez, Milagros

    2008-03-01

    This article presents and discusses strategies implemented by the University of Puerto Rico Center for Hispanic Youth Violence Prevention (CHYVP) to facilitate community mobilization to reduce youth violence in a high-risk Latino community. Participatory communication strategies were used to enhance mobilization and to develop community partnerships. Short-term outcomes included overcoming resistance and distrust, active community dialogue and consensus building, the development of a school-community task force, the identification of priorities, the negotiation of conflicts, the implementation of a common action plan, and the commitment of government officials to adopt community recommendations. Challenges included gaining trust, inadequate coordination among partners, diversity within the community, dealing with prejudice, enhancing male participation, working at the community's pace, party politics, and the effect of the loss of funding and its impact on the community. A participatory communication process can help to mobilize Latino communities to prevent and reduce youth violence.

  12. Organic Synthetic Advanced Materials for Optoelectronic and Energy Applications (at Center for Condensed Matter Sciences)

    SciTech Connect

    Yen, Hung-Ju

    2016-11-14

    These slides cover Hung-Ju Yen's recent work in the synthesis and structural design of functional materials, which were further used for optoelectronic and energy applications, such as lithium ion battery, solar cell, LED, electrochromic, and fuel cells. This was for a job interview at Center for Condensed Matter Sciences. The following topics are detailed: current challenges for lithium-ion batteries; graphene, graphene oxide and nanographene; nanographenes with various functional groups; fine tune d-spacing through organic synthesis: varying functional group; schematic view of LIBs; nanographenes as LIB anode; rate performance (charging-discharging); electrochromic technology; electrochromic materials; advantages of triphenylamine; requirement of electrochromic materials for practical applications; low driving voltage and long cycle life; increasing the electroactive sites by multi-step synthetic procedures; synthetic route to starburst triarylamine-based polyamide; electrochromism ranging from visible to NIR region; transmissive to black electrochromism; RGB and CMY electrochromism.

  13. Human Factors Process Task Analysis Liquid Oxygen Pump Acceptance Test Procedure for the Advanced Technology Development Center

    NASA Technical Reports Server (NTRS)

    Diorio, Kimberly A.

    2002-01-01

    A process task analysis effort was undertaken by Dynacs Inc. commencing in June 2002 under contract from NASA YA-D6. Funding was provided through NASA's Ames Research Center (ARC), Code M/HQ, and Industrial Engineering and Safety (IES). The John F. Kennedy Space Center (KSC) Engineering Development Contract (EDC) Task Order was 5SMA768. The scope of the effort was to conduct a Human Factors Process Failure Modes and Effects Analysis (HF PFMEA) of a hazardous activity and provide recommendations to eliminate or reduce the effects of errors caused by human factors. The Liquid Oxygen (LOX) Pump Acceptance Test Procedure (ATP) was selected for this analysis. The HF PFMEA table (see appendix A) provides an analysis of six major categories evaluated for this study. These categories include Personnel Certification, Test Procedure Format, Test Procedure Safety Controls, Test Article Data, Instrumentation, and Voice Communication. For each specific requirement listed in appendix A, the following topics were addressed: Requirement, Potential Human Error, Performance-Shaping Factors, Potential Effects of the Error, Barriers and Controls, Risk Priority Numbers, and Recommended Actions. This report summarizes findings and gives recommendations as determined by the data contained in appendix A. It also includes a discussion of technology barriers and challenges to performing task analyses, as well as lessons learned. The HF PFMEA table in appendix A recommends the use of accepted and required safety criteria in order to reduce the risk of human error. The items with the highest risk priority numbers should receive the greatest amount of consideration. Implementation of the recommendations will result in a safer operation for all personnel.

  14. Precision and manufacturing at the Lawrence Livermore National Laboratory

    SciTech Connect

    Saito, T.T.; Wasley, R.J.; Stowers, I.F.; Donaldson, R.R.; Thompson, D.C.

    1993-11-01

    Precision Engineering is one of Lawrence Livermore National Laboratory`s core strengths. This paper discusses the past and present current technology transfer efforts of LLNL`s Precision Engineering program and the Livermore Center for Advanced Manufacturing and Productivity (LCAMP). More than a year ago the Precision Machining Commercialization project embodied several successful methods of transferring high technology from the National Laboratories to industry. Currently LCAMP has already demonstrated successful technology transfer and is involved in a broad spectrum of current programs. In addition this paper discusses other technologies ripe for future transition including the Large Optics Diamond Turning Machine.

  15. Precision and manufacturing at the Lawrence Livermore National Laboratory

    NASA Technical Reports Server (NTRS)

    Saito, Theodore T.; Wasley, Richard J.; Stowers, Irving F.; Donaldson, Robert R.; Thompson, Daniel C.

    1994-01-01

    Precision Engineering is one of the Lawrence Livermore National Laboratory's core strengths. This paper discusses the past and present current technology transfer efforts of LLNL's Precision Engineering program and the Livermore Center for Advanced Manufacturing and Productivity (LCAMP). More than a year ago the Precision Machine Commercialization project embodied several successful methods of transferring high technology from the National Laboratories to industry. Currently, LCAMP has already demonstrated successful technology transfer and is involved in a broad spectrum of current programs. In addition, this paper discusses other technologies ripe for future transition including the Large Optics Diamond Turning Machine.

  16. Advancing Cancer Systems Biology: Introducing the Center for the Development of a Virtual Tumor, CViT

    PubMed Central

    Deisboeck, Thomas S.; Zhang, Le; Martin, Sean

    2007-01-01

    Integrative cancer biology research relies on a variety of data-driven computational modeling and simulation methods and techniques geared towards gaining new insights into the complexity of biological processes that are of critical importance for cancer research. These include the dynamics of gene-protein interaction networks, the percolation of sub-cellular perturbations across scales and the impact they may have on tumorigenesis in both experiments and clinics. Such innovative ‘systems’ research will greatly benefit from enabling Information Technology that is currently under development, including an online collaborative environment, a Semantic Web based computing platform that hosts data and model repositories as well as high-performance computing access. Here, we present one of the National Cancer Institute’s recently established Integrative Cancer Biology Programs, i.e. the Center for the Development of a Virtual Tumor, CViT, which is charged with building a cancer modeling community, developing the aforementioned enabling technologies and fostering multi-scale cancer modeling and simulation. PMID:19390664

  17. Integrated flexible manufacturing program for manufacturing automation and rapid prototyping

    NASA Technical Reports Server (NTRS)

    Brooks, S. L.; Brown, C. W.; King, M. S.; Simons, W. R.; Zimmerman, J. J.

    1993-01-01

    The Kansas City Division of Allied Signal Inc., as part of the Integrated Flexible Manufacturing Program (IFMP), is developing an integrated manufacturing environment. Several systems are being developed to produce standards and automation tools for specific activities within the manufacturing environment. The Advanced Manufacturing Development System (AMDS) is concentrating on information standards (STEP) and product data transfer; the Expert Cut Planner system (XCUT) is concentrating on machining operation process planning standards and automation capabilities; the Advanced Numerical Control system (ANC) is concentrating on NC data preparation standards and NC data generation tools; the Inspection Planning and Programming Expert system (IPPEX) is concentrating on inspection process planning, coordinate measuring machine (CMM) inspection standards and CMM part program generation tools; and the Intelligent Scheduling and Planning System (ISAPS) is concentrating on planning and scheduling tools for a flexible manufacturing system environment. All of these projects are working together to address information exchange, standardization, and information sharing to support rapid prototyping in a Flexible Manufacturing System (FMS) environment.

  18. Fabric Manufacturing

    NASA Technical Reports Server (NTRS)

    1986-01-01

    When rapid oscillation of blanket wearing looms at Chatham Manufacturing Company caused significant metal fatigue, the company turned to NC/STRC for a NASA data bank computer search. The search pinpointed tensile stress, and suggested a built-in residual compressive stress as a solution. "Shot peening," bombarding a part with a high velocity stream of very small shot to pound and compress the part's surface, was found to be the only practical method for creating compressive stress. The method has been successful and the company estimates its annual savings as a quarter million dollars.

  19. Industrial Assessment Center Program

    SciTech Connect

    Kolarik, William J.

    2007-02-26

    Over the five-year period (2002-2006) the Oklahoma State University Industrial Assessment Center (IAC) performed energy assessments for 106 different clients, writing 835 recommendations, for a total of $23,937,099 in potential estimated annual savings. IAC clients served consisted of small and medium-sized manufacturers ranging from food manufactures to foundries. The OSU IAC served clients in Oklahoma, Kansas, Missouri, Arkansas, and Texas. In addition to client service, student training and instruction was a major accomplishment. The OSU IAC employed (and trained) 12 baccalaureate-level students, 17 masters-level graduate students, and 7 doctoral-level graduate students. Most are practicing in the energy management area. Training was focused on both energy assessment and safety. Safety training was both center-based training as well as on-site training. Energy management related training was focused on classroom (for academic credit) work at both the undergraduate and graduate level. IEM 4923 (Energy and Water Management) was developed to serve both the IAC as well as non-IAC students. It was delivered once per year, with enrollments of typically 10 to 20 students. This course was required for IAC student employees, both undergraduate and graduate. This course was patterned after the AEE CEM (five-day) course for practicing professionals. IEM 4923 required each student to attend at least one on-site assessment and write at least one recommendation for their client’s report. Hence, a hands-on approach was practiced. Advance level courses were used to train graduate students. Two courses played major roles here: IEM 5923 (Advanced Energy and Water Management) and IEM 5943 (Hazardous Material and Waste). Graduate student participation in these courses helped the IAC to gain additional perspectives in on-site assessment and resulting recommendations. Numerous hands-on demonstration/training was conducted by directors and graduate students in order to gain

  20. Nurse Mentors to Advance Quality Improvement in Primary Health Centers: Lessons From a Pilot Program in Northern Karnataka, India

    PubMed Central

    Fischer, Elizabeth A; Jayana, Krishnamurthy; Cunningham, Troy; Washington, Maryann; Mony, Prem; Bradley, Janet; Moses, Stephen

    2015-01-01

    High-quality care during labor, delivery, and the postpartum period is critically important since maternal and child morbidity and mortality are linked to complications that arise during these stages. A nurse mentoring program was implemented in northern Karnataka, India, to improve quality of services at primary health centers (PHCs), the lowest level in the public health system that offers basic obstetric care. The intervention, conducted between August 2012 and July 2014, employed 53 full-time nurse mentors and was scaled-up in 385 PHCs in 8 poor rural districts. Each mentor was responsible for 6 to 8 PHCs and conducted roughly 6 mentoring visits per PHC in the first year. This paper reports the results of a qualitative inquiry, conducted between September 2012 and April 2014, assessing the program's successes and challenges from the perspective of mentors and PHC teams. Data were gathered through 13 observations, 9 focus group discussions with mentors, and 25 individual and group interviews with PHC nurses, medical officers, and district health officers. Mentors and PHC staff and leaders reported a number of successes, including development of rapport and trust between mentors and PHC staff, introduction of team-based quality improvement processes, correct and consistent use of a new case sheet to ensure adherence to clinical guidelines, and increases in staff nurses’ knowledge and skills. Overall, nurses in many PHCs reported an increased ability to provide care according to guidelines and to handle maternal and newborn complications, along with improvements in equipment and supplies and referral management. Challenges included high service delivery volumes and/or understaffing at some PHCs, unsupportive or absent PHC leadership, and cultural practices that impacted quality. Comprehensive mentoring can build competence and improve performance by combining on-the-job clinical and technical support, applying quality improvement principles, and promoting team

  1. Nurse Mentors to Advance Quality Improvement in Primary Health Centers: Lessons From a Pilot Program in Northern Karnataka, India.

    PubMed

    Fischer, Elizabeth A; Jayana, Krishnamurthy; Cunningham, Troy; Washington, Maryann; Mony, Prem; Bradley, Janet; Moses, Stephen

    2015-12-01

    High-quality care during labor, delivery, and the postpartum period is critically important since maternal and child morbidity and mortality are linked to complications that arise during these stages. A nurse mentoring program was implemented in northern Karnataka, India, to improve quality of services at primary health centers (PHCs), the lowest level in the public health system that offers basic obstetric care. The intervention, conducted between August 2012 and July 2014, employed 53 full-time nurse mentors and was scaled-up in 385 PHCs in 8 poor rural districts. Each mentor was responsible for 6 to 8 PHCs and conducted roughly 6 mentoring visits per PHC in the first year. This paper reports the results of a qualitative inquiry, conducted between September 2012 and April 2014, assessing the program's successes and challenges from the perspective of mentors and PHC teams. Data were gathered through 13 observations, 9 focus group discussions with mentors, and 25 individual and group interviews with PHC nurses, medical officers, and district health officers. Mentors and PHC staff and leaders reported a number of successes, including development of rapport and trust between mentors and PHC staff, introduction of team-based quality improvement processes, correct and consistent use of a new case sheet to ensure adherence to clinical guidelines, and increases in staff nurses' knowledge and skills. Overall, nurses in many PHCs reported an increased ability to provide care according to guidelines and to handle maternal and newborn complications, along with improvements in equipment and supplies and referral management. Challenges included high service delivery volumes and/or understaffing at some PHCs, unsupportive or absent PHC leadership, and cultural practices that impacted quality. Comprehensive mentoring can build competence and improve performance by combining on-the-job clinical and technical support, applying quality improvement principles, and promoting team

  2. Center for Automation and Manufacturing Science.

    DTIC Science & Technology

    1986-09-01

    light and rigid compared with the flexible beam, and is controlled by a separate DC motor. A lamp is mounted at the tip of the wrist to indicate the...Generi- cally, when a robot manipulator is used either in a fabrication or assembly job, the area of workstation is small compared with the reachable...adaptive control schemes, several dynamic control schemes, and two parameter estimation schemes - with considerable time saving as compared to

  3. Center of Excellence in Aerospace Manufacturing Automation

    DTIC Science & Technology

    1983-11-01

    developments described here. Professor Binford has participated as a sub-contractor to Honeywell along with Unima - tion West (now Adept Technology Inc...effective kind: with people in joint efforts. Professor Binford has participated as a sub-contractor to Honeywell along with Unima - tion West (now Adept

  4. Marshall Space Flight Center Materials and Processes Laboratory

    NASA Technical Reports Server (NTRS)

    Tramel, Terri L.

    2012-01-01

    Marshall?s Materials and Processes Laboratory has been a core capability for NASA for over fifty years. MSFC has a proven heritage and recognized expertise in materials and manufacturing that are essential to enable and sustain space exploration. Marshall provides a "systems-wise" capability for applied research, flight hardware development, and sustaining engineering. Our history of leadership and achievements in materials, manufacturing, and flight experiments includes Apollo, Skylab, Mir, Spacelab, Shuttle (Space Shuttle Main Engine, External Tank, Reusable Solid Rocket Motor, and Solid Rocket Booster), Hubble, Chandra, and the International Space Station. MSFC?s National Center for Advanced Manufacturing, NCAM, facilitates major M&P advanced manufacturing partnership activities with academia, industry and other local, state and federal government agencies. The Materials and Processes Laborato ry has principal competencies in metals, composites, ceramics, additive manufacturing, materials and process modeling and simulation, space environmental effects, non-destructive evaluation, and fracture and failure analysis provide products ranging from materials research in space to fully integrated solutions for large complex systems challenges. Marshall?s materials research, development and manufacturing capabilities assure that NASA and National missions have access to cutting-edge, cost-effective engineering design and production options that are frugal in using design margins and are verified as safe and reliable. These are all critical factors in both future mission success and affordability.

  5. Virtually simulating the next generation of clean energy technologies: NETL's AVESTAR Center is dedicated to the safe, reliable and efficient operation of advanced energy plants with carbon capture

    SciTech Connect

    Zitney, S.

    2012-01-01

    Imagine using a real-time virtual simulator to learn to fly a space shuttle or rebuild your car's transmission without touching a piece of equipment or getting your hands dirty. Now, apply this concept to learning how to operate and control a state-of-the-art, electricity-producing power plant capable of carbon dioxide (CO{sub 2}) capture. That's what the National Energy Technology Laboratory's (NETL) Advanced Virtual Energy Simulation Training and Research (AVESTAR) Center (www.netl.doe.gov/avestar) is designed to do. Established as part of the Department of Energy's (DOE) initiative to advance new clean energy technology for power generation, the AVESTAR Center focuses primarily on providing simulation-based training for process engineers and energy plant operators, starting with the deployment of a first-of-a-kind operator training simulator for an integrated gasification combined cycle (IGCC) power plant with CO{sub 2} capture. The IGCC dynamic simulator builds on, and reaches beyond, conventional power plant simulators to merge, for the first time, a 'gasification with CO{sub 2} capture' process simulator with a 'combined-cycle' power simulator. Based on Invensys Operations Management's SimSci-Esscor DYNSIM software, the high-fidelity dynamic simulator provides realistic training on IGCC plant operations, including normal and faulted operations, as well as plant start-up, shutdown and power demand load changes. The highly flexible simulator also allows for testing of different types of fuel sources, such as petcoke and biomass, as well as co-firing fuel mixtures. The IGCC dynamic simulator is available at AVESTAR's two locations, NETL (Figure 1) and West Virginia University's National Research Center for Coal and Energy (www.nrcce.wvu.edu), both in Morgantown, W.Va. By offering a comprehensive IGCC training program, AVESTAR aims to develop a workforce well prepared to operate, control and manage commercial-scale gasification-based power plants with CO{sub 2

  6. The Advanced Solid Rocket Motor

    NASA Technical Reports Server (NTRS)

    Mitchell, Royce E.

    1992-01-01

    The Advanced Solid Rocket Motor will utilize improved design features and automated manufacturing methods to produce an inherently safer propulsive system for the Space Shuttle and future launch systems. This second-generation motor will also provide an additional 12,000 pounds of payload to orbit, enhancing the utility and efficiency of the Shuttle system. The new plant will feature strip-wound, asbestos-free insulation; propellant continuous mixing and casting; and extensive robotic systems. Following a series of static tests at the Stennis Space Center, MS flights are targeted to begin in early 1997.

  7. The Advanced Solid Rocket Motor

    NASA Astrophysics Data System (ADS)

    Mitchell, Royce E.

    1992-08-01

    The Advanced Solid Rocket Motor will utilize improved design features and automated manufacturing methods to produce an inherently safer propulsive system for the Space Shuttle and future launch systems. This second-generation motor will also provide an additional 12,000 pounds of payload to orbit, enhancing the utility and efficiency of the Shuttle system. The new plant will feature strip-wound, asbestos-free insulation; propellant continuous mixing and casting; and extensive robotic systems. Following a series of static tests at the Stennis Space Center, MS flights are targeted to begin in early 1997.

  8. Design and manufacturing of composites

    SciTech Connect

    Hoa, S.V.; Hamada, H.

    1998-12-31

    This workshop presents cutting edge technical information on latest advances in the field. It provides a unique forum for interaction between researchers, engineers and scientists. The technical presentations cover a vast range of composite topics, including thermoplastic, metal matrix, ceramic, smart, textile, manufacturing methods, fatigue and failure, analysis and modeling, and design/applications.

  9. Preparing the Next American Manufacturing Workforce

    ERIC Educational Resources Information Center

    Taraman, Khalil S.

    2010-01-01

    Manufacturing has a new face--and the future it offers is exciting. But in order to take advantage of what it offers, one needs a plan and he/she has to know how to execute it. In this article, the author discusses how the Society of Manufacturing Engineers (SME) is working to get the message out that the future of advanced manufacturing will…

  10. Ultra-precision processes for optics manufacturing

    NASA Technical Reports Server (NTRS)

    Martin, William R.

    1991-01-01

    The Optics MODIL (Manufacturing Operations Development and Integration Laboratory) is developing advanced manufacturing technologies for fabrication of ultra precision optical components, aiming for a ten-fold improvement in precision and a shortening of the scheduled lead time. Current work focuses on diamond single point turning, ductile grinding, ion milling, and in/on process metrology.

  11. Ultra-precision processes for optics manufacturing

    NASA Astrophysics Data System (ADS)

    Martin, William R.

    1991-12-01

    The Optics MODIL (Manufacturing Operations Development and Integration Laboratory) is developing advanced manufacturing technologies for fabrication of ultra precision optical components, aiming for a ten-fold improvement in precision and a shortening of the scheduled lead time. Current work focuses on diamond single point turning, ductile grinding, ion milling, and in/on process metrology.

  12. Manufacturing Careers, Skilled Workers and the Economy

    ERIC Educational Resources Information Center

    Martino, Lisa

    2011-01-01

    In order to jumpstart the economy, "Made in the U.S.A." needs to be synonymous with in-demand, high-quality products sold throughout the world. Recognizing the importance of the manufacturing industry and its connection to a healthy economy, President Obama addressed Carnegie Mellon University and launched the Advanced Manufacturing Partnership…

  13. Challenges in teaching modern manufacturing technologies

    NASA Astrophysics Data System (ADS)

    Ngaile, Gracious; Wang, Jyhwen; Gau, Jenn-Terng

    2015-07-01

    Teaching of manufacturing courses for undergraduate engineering students has become a challenge due to industrial globalisation coupled with influx of new innovations, technologies, customer-driven products. This paper discusses development of a modern manufacturing course taught concurrently in three institutions where students collaborate in executing various projects. Lectures are developed to contain materials featuring advanced manufacturing technologies, R&D trends in manufacturing. Pre- and post-surveys were conducted by an external evaluator to assess the impact of the course on increase in student's knowledge of manufacturing; increase students' preparedness and confidence in effective communication and; increase students' interest in pursuing additional academic studies and/or a career path in manufacturing and high technology. The surveyed data indicate that the students perceived significant gains in manufacturing knowledge and preparedness in effective communication. The study also shows that implementation of a collaborative course within multiple institutions requires a robust and collective communication platform.

  14. Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study

    PubMed Central

    Gonçalves, Anthony; Bertucci, François; Guille, Arnaud; Garnier, Severine; Adelaide, José; Carbuccia, Nadine; Cabaud, Oliver; Finetti, Pascal; Brunelle, Serge; Piana, Gilles; Tomassin-Piana, Jeanne; Paciencia, Maria; Lambaudie, Eric; Popovici, Cornel; Sabatier, Renaud; Tarpin, Carole; Provansal, Magali; Extra, Jean-Marc; Eisinger, François; Sobol, Hagay; Viens, Patrice; Lopez, Marc; Ginestier, Christophe; Charafe-Jauffret, Emmanuelle; Chaffanet, Max; Birnbaum, Daniel

    2016-01-01

    Background Routine feasibility and clinical impact of genomics-based tumor profiling in advanced breast cancer (aBC) remains to be determined. We conducted a pilot study to evaluate whether precision medicine could be prospectively implemented for aBC patients in a single center and to examine whether patient-derived tumor xenografts (PDX) could be obtained in this population. Results Thirty-four aBC patients were included. Actionable targets were found in 28 patients (82%). A targeted therapy could be proposed to 22 patients (64%), either through a clinical trial (n=15) and/or using already registered drugs (n=21). Ten patients (29%) eventually received targeted treatment, 2 of them deriving clinical benefit. Of 22 patients subjected to mouse implantation, 10 had successful xenografting (45%), mostly in triple-negative aBC. Methods aBC patients accessible to tumor biopsy were prospectively enrolled at the Institut Paoli-Calmettes in the BC-BIO study (ClinicalTrials.gov, NCT01521676). Genomic profiling was established by whole-genome array comparative genomic hybridization (aCGH) and targeted next-generation sequencing (NGS) of 365 candidate cancer genes. For a subset of patients, a sample of fresh tumor was orthotopically implanted in humanized cleared fat pads of NSG mice for establishing PDX. Conclusions Precision medicine can be implemented in a single center in the context of clinical practice and may allow genomic-driven treatment in approximately 30% of aBC patients. PDX may be obtained in a significant fraction of cases. PMID:27765906

  15. Analysis of residual stress and hardness in regions of pre-manufactured and manual bends in fixation plates for maxillary advancement.

    PubMed

    Araújo, Marcelo Marotta; Lauria, Andrezza; Mendes, Marcelo Breno Meneses; Claro, Ana Paula Rosifini Alves; Claro, Cristiane Aparecida de Assis; Moreira, Roger William Fernandes

    2015-12-01

    The aim of this study was to analyze, through Vickers hardness test and photoelasticity analysis, pre-bent areas, manually bent areas, and areas without bends of 10-mm advancement pre-bent titanium plates (Leibinger system). The work was divided into three groups: group I-region without bend, group II-region of 90° manual bend, and group III-region of 90° pre-fabricated bends. All the materials were evaluated through hardness analysis by the Vickers hardness test, stress analysis by residual images obtained in a polariscope, and photoelastic analysis by reflection during the manual bending. The data obtained from the hardness tests were statistically analyzed using ANOVA and Tukey's tests at a significance level of 5 %. The pre-bent plate (group III) showed hardness means statistically significantly higher (P < 0.05) than those of the other groups (I-region without bends, II-90° manually bent region). Through the study of photoelastic reflection, it was possible to identify that the stress gradually increased, reaching a pink color (1.81 δ / λ), as the bending was performed. A general analysis of the results showed that the bent plate region of pre-bent titanium presented the best results.

  16. Advanced 3D mesh manipulation in stereolithographic files and post-print processing for the manufacturing of patient-specific vascular flow phantoms

    NASA Astrophysics Data System (ADS)

    O'Hara, Ryan P.; Chand, Arpita; Vidiyala, Sowmya; Arechavala, Stacie M.; Mitsouras, Dimitrios; Rudin, Stephen; Ionita, Ciprian N.

    2016-03-01

    Complex vascular anatomies can cause the failure of image-guided endovascular procedures. 3D printed patient-specific vascular phantoms provide clinicians and medical device companies the ability to preemptively plan surgical treatments, test the likelihood of device success, and determine potential operative setbacks. This research aims to present advanced mesh manipulation techniques of stereolithographic (STL) files segmented from medical imaging and post-print surface optimization to match physiological vascular flow resistance. For phantom design, we developed three mesh manipulation techniques. The first method allows outlet 3D mesh manipulations to merge superfluous vessels into a single junction, decreasing the number of flow outlets and making it feasible to include smaller vessels. Next we introduced Boolean operations to eliminate the need to manually merge mesh layers and eliminate errors of mesh self-intersections that previously occurred. Finally we optimize support addition to preserve the patient anatomical geometry. For post-print surface optimization, we investigated various solutions and methods to remove support material and smooth the inner vessel surface. Solutions of chloroform, alcohol and sodium hydroxide were used to process various phantoms and hydraulic resistance was measured and compared with values reported in literature. The newly mesh manipulation methods decrease the phantom design time by 30 - 80% and allow for rapid development of accurate vascular models. We have created 3D printed vascular models with vessel diameters less than 0.5 mm. The methods presented in this work could lead to shorter design time for patient specific phantoms and better physiological simulations.

  17. Machine Tool Advanced Skills Technology (MAST). Common Ground: Toward a Standards-Based Training System for the U.S. Machine Tool and Metal Related Industries. Volume 15: Administrative Information, of a 15-Volume Set of Skill Standards and Curriculum Training Materials for the Precision Manufacturing Industry.

    ERIC Educational Resources Information Center

    Texas State Technical Coll., Waco.

    This volume developed by the Machine Tool Advanced Skill Technology (MAST) program contains key administrative documents and provides additional sources for machine tool and precision manufacturing information and important points of contact in the industry. The document contains the following sections: a foreword; grant award letter; timeline for…

  18. Toward a Global Community of Scholars. The Special Partnership between the Carnegie Foundation for the Advancement of Teaching and China's National Center for Education Development Research, 1988-1997.

    ERIC Educational Resources Information Center

    Ch'i, Hsi-sheng

    This volume traces the history of a collaboration between the Carnegie Foundation for the Advancement of Teaching and China's National Center for Education Development Research. The collaboration, which began in 1988, was initiated to conduct a comparative study of education in the two countries through information exchanges and seminars.…

  19. Southern Energy Efficiency Center (SEEC)

    SciTech Connect

    Vieira, Robin; Sonne, Jeffrey; Withers, Charles; Cummings, James; Verdict, Malcolm; Roberts, Sydney

    2009-09-30

    The Southern Energy Efficiency Center (SEEC) builds collaborative partnerships with: state and local governments and their program support offices, the building delivery industry (designers, contractors, realtors and commissioning agents), product manufacturers and their supply chains, utilities and their program implementers, consumers and other stakeholders in order to forge a strong regional network of building energy efficiency allies. Through a project Steering Committee composed of the state energy offices and building industry stakeholders, the SEEC works to establish consensus-based goals, priorities and strategies at the regional, state and local levels that will materially advance the deployment of high-performance “beyond code” buildings. In its first Phase, SEEC will provide limited technical and policy support assistance, training, certification and education to a wide spectrum of the building construction, codes and standards, and the consumer marketplace.

  20. Center for Advanced Propulsion Systems

    DTIC Science & Technology

    1993-02-01

    engine also has a Bowditch -type see-through piston. The instrumentation port was used to measure surface temperature from which the instantaneous heat...Analytical Correction for Small Viscous Heating Errors. Rheological Acta. November/December, 28,464-472. Lodge, A., Pritchard, W., and Scott , L. (1991