Aerodynamics of the advanced launch system (ALS) propulsion and avionics (P/A) module

NASA Technical Reports Server (NTRS)

Ferguson, Stan; Savage, Dick

1992-01-01

This paper discusses the design and testing of candidate Advanced Launch System (ALS) Propulsion and Avionics (P/A) Module configurations. The P/A Module is a key element of future launch systems because it is essential to the recovery and reuse of high-value propulsion and avionics hardware. The ALS approach involves landing of first stage (booster) and/or second stage (core) P/A modules near the launch site to minimize logistics and refurbishment cost. The key issue addressed herein is the aerodynamic design of the P/A module, including the stability characteristics and the lift-to-drag (L/D) performance required to achieve the necessary landing guidance accuracy. The reference P/A module configuration was found to be statically stable for the desired flight regime, to provide adequate L/D for targeting, and to have effective modulation of the L/D performance using a body flap. The hypersonic aerodynamic trends for nose corner radius, boattail angle and body flap deflections were consistent with pretest predictions. However, the levels for the L/D and axial force for hypersonic Mach numbers were overpredicted by impact theories.

Large Advanced Space Systems (LASS) computer-aided design program additions

NASA Technical Reports Server (NTRS)

Farrell, C. E.

1982-01-01

The LSS preliminary and conceptual design requires extensive iteractive analysis because of the effects of structural, thermal, and control intercoupling. A computer aided design program that will permit integrating and interfacing of required large space system (LSS) analyses is discussed. The primary objective of this program is the implementation of modeling techniques and analysis algorithms that permit interactive design and tradeoff studies of LSS concepts. Eight software modules were added to the program. The existing rigid body controls module was modified to include solar pressure effects. The new model generator modules and appendage synthesizer module are integrated (interfaced) to permit interactive definition and generation of LSS concepts. The mass properties module permits interactive specification of discrete masses and their locations. The other modules permit interactive analysis of orbital transfer requirements, antenna primary beam n, and attitude control requirements.

Basic avionics module design for general aviation aircraft

NASA Technical Reports Server (NTRS)

Smyth, R. K.; Smyth, D. E.

1978-01-01

The design of an advanced digital avionics system (basic avionics module) for general aviation aircraft operated with a single pilot under IFR conditions is described. The microprocessor based system provided all avionic functions, including flight management, navigation, and lateral flight control. The mode selection was interactive with the pilot. The system used a navigation map data base to provide operation in the current and planned air traffic control environment. The system design included software design listings for some of the required modules. The distributed microcomputer uses the IEEE 488 bus for interconnecting the microcomputer and sensors.

Severe Accident Test Station Design Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snead, Mary A.; Yan, Yong; Howell, Michael

The purpose of the ORNL severe accident test station (SATS) is to provide a platform for evaluation of advanced fuels under projected beyond design basis accident (BDBA) conditions. The SATS delivers the capability to map the behavior of advanced fuels concepts under accident scenarios across various temperature and pressure profiles, steam and steam-hydrogen gas mixtures, and thermal shock. The overall facility will include parallel capabilities for examination of fuels and irradiated materials (in-cell) and non-irradiated materials (out-of-cell) at BDBA conditions as well as design basis accident (DBA) or loss of coolant accident (LOCA) conditions. Also, a supporting analytical infrastructure tomore » provide the data-needs for the fuel-modeling components of the Fuel Cycle Research and Development (FCRD) program will be put in place in a parallel manner. This design report contains the information for the first, second and third phases of design and construction of the SATS. The first phase consisted of the design and construction of an out-of-cell BDBA module intended for examination of non-irradiated materials. The second phase of this work was to construct the BDBA in-cell module to test irradiated fuels and materials as well as the module for DBA (i.e. LOCA) testing out-of-cell, The third phase was to build the in-cell DBA module. The details of the design constraints and requirements for the in-cell facility have been closely captured during the deployment of the out-of-cell SATS modules to ensure effective future implementation of the in-cell modules.« less

Integrated residential photovoltaic array development

NASA Astrophysics Data System (ADS)

Shepard, N. F., Jr.

1981-12-01

An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

Integrated residential photovoltaic array development

NASA Technical Reports Server (NTRS)

Shepard, N. F., Jr.

1981-01-01

An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

Advanced space system analysis software. Technical, user, and programmer guide

NASA Technical Reports Server (NTRS)

Farrell, C. E.; Zimbelman, H. F.

1981-01-01

The LASS computer program provides a tool for interactive preliminary and conceptual design of LSS. Eight program modules were developed, including four automated model geometry generators, an associated mass properties module, an appendage synthesizer module, an rf analysis module, and an orbital transfer analysis module. The existing rigid body controls analysis module was modified to permit analysis of effects of solar pressure on orbital performance. A description of each module, user instructions, and programmer information are included.

Advanced optical fiber communication systems

NASA Astrophysics Data System (ADS)

Kazovsky, Leonid G.

1994-03-01

Our research is focused on three major aspects of advanced optical fiber communication systems: dynamic wavelength division multiplexing (WDM) networks, fiber nonlinearities, and high dynamic range coherent analog optical links. In the area of WDM networks, we have designed and implemented two high-speed interface boards and measured their throughput and latency. Furthermore, we designed and constructed an experimental PSK/ASK transceiver that simultaneously transmits packet-switched ASK data and circuit-switched PSK data on the same optical carrier. In the area of fiber nonlinearities, we investigated the theoretical impact of modulation frequency on cross-phase modulation (XPM) in dispersive fibers. In the area of high dynamic range coherent analog optical links, we developed theoretical expressions for the RF power transfer ratio (or RF power gain) and the noise figure (NF) of angle-modulated links. We then compared the RF power gains and noise figures of these links to that of an intensity modulated direct detection (DD) link.

Electrochemical carbon dioxide concentrator advanced technology tasks

NASA Technical Reports Server (NTRS)

Schneider, J. J.; Schubert, F. H.; Hallick, T. M.; Woods, R. R.

1975-01-01

Technology advancement studies are reported on the basic electrochemical CO2 removal process to provide a basis for the design of the next generation cell, module and subsystem hardware. An Advanced Electrochemical Depolarized Concentrator Module (AEDCM) is developed that has the characteristics of low weight, low volume, high CO2, removal, good electrical performance and low process air pressure drop. Component weight and noise reduction for the hardware of a six man capacity CO2 collection subsystem was developed for the air revitalization group of the Space Station Prototype (SSP).

Multiplexing electro-optic architectures for advanced aircraft integrated flight control systems

NASA Technical Reports Server (NTRS)

Seal, D. W.

1989-01-01

This report describes the results of a 10 month program sponsored by NASA. The objective of this program was to evaluate various optical sensor modulation technologies and to design an optimal Electro-Optic Architecture (EOA) for servicing remote clusters of sensors and actuators in advanced aircraft flight control systems. The EOA's supply optical power to remote sensors and actuators, process the modulated optical signals returned from the sensors, and produce conditioned electrical signals acceptable for use by a digital flight control computer or Vehicle Management System (VMS) computer. This study was part of a multi-year initiative under the Fiber Optic Control System Integration (FOCSI) program to design, develop, and test a totally integrated fiber optic flight/propulsion control system for application to advanced aircraft. Unlike earlier FOCSI studies, this program concentrated on the design of the EOA interface rather than the optical transducer technology itself.

Ultra-Wideband Optical Modulation Spectrometer (OMS) Development: Study of the Optical Setup of a Wide-Band Optical Modulation Spectrometer

NASA Technical Reports Server (NTRS)

Tolls, Volker; Stringfellow, Guy (Technical Monitor)

2001-01-01

The purpose of this study is to advance the design of the optical setup for a wide-band Optical Modulation Spectrometer (OMS) for use with astronomical heterodyne receiver systems. This report describes the progress of this investigation achieved from March until December 2001.

Design of selective nuclear receptor modulators: RAR and RXR as a case study.

PubMed

de Lera, Angel R; Bourguet, William; Altucci, Lucia; Gronemeyer, Hinrich

2007-10-01

Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are members of the nuclear receptor superfamily whose effects on cell growth and survival can be modulated therapeutically by small-molecule ligands. Although compounds that target these receptors are powerful anticancer drugs, their use is limited by toxicity. An improved understanding of the structural biology of RXRs and RARs and recent advances in the chemical synthesis of modified retinoid and rexinoid ligands should enable the rational design of more selective agents that might overcome such problems. Here, we review structural data for RXRs and RARs, discuss strategies in the design of selective RXR and RAR modulators, and consider lessons that can be learned for the design of selective nuclear-receptor modulators in general.

The Design and Implementation of NASA's Advanced Flight Computing Module

NASA Technical Reports Server (NTRS)

Alkakaj, Leon; Straedy, Richard; Jarvis, Bruce

1995-01-01

This paper describes a working flight computer Multichip Module developed jointly by JPL and TRW under their respective research programs in a collaborative fashion. The MCM is fabricated by nCHIP and is packaged within a 2 by 4 inch Al package from Coors. This flight computer module is one of three modules under development by NASA's Advanced Flight Computer (AFC) program. Further development of the Mass Memory and the programmable I/O MCM modules will follow. The three building block modules will then be stacked into a 3D MCM configuration. The mass and volume of the flight computer MCM achieved at 89 grams and 1.5 cubic inches respectively, represent a major enabling technology for future deep space as well as commercial remote sensing applications.

Advanced earth observation spacecraft computer-aided design software: Technical, user and programmer guide

NASA Technical Reports Server (NTRS)

Farrell, C. E.; Krauze, L. D.

1983-01-01

The IDEAS computer of NASA is a tool for interactive preliminary design and analysis of LSS (Large Space System). Nine analysis modules were either modified or created. These modules include the capabilities of automatic model generation, model mass properties calculation, model area calculation, nonkinematic deployment modeling, rigid-body controls analysis, RF performance prediction, subsystem properties definition, and EOS science sensor selection. For each module, a section is provided that contains technical information, user instructions, and programmer documentation.

Update on ORNL TRANSFORM Tool: Simulating Multi-Module Advanced Reactor with End-to-End I&C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hale, Richard Edward; Fugate, David L.; Cetiner, Sacit M.

2015-05-01

The Small Modular Reactor (SMR) Dynamic System Modeling Tool project is in the fourth year of development. The project is designed to support collaborative modeling and study of various advanced SMR (non-light water cooled reactor) concepts, including the use of multiple coupled reactors at a single site. The focus of this report is the development of a steam generator and drum system model that includes the complex dynamics of typical steam drum systems, the development of instrumentation and controls for the steam generator with drum system model, and the development of multi-reactor module models that reflect the full power reactormore » innovative small module design concept. The objective of the project is to provide a common simulation environment and baseline modeling resources to facilitate rapid development of dynamic advanced reactor models; ensure consistency among research products within the Instrumentation, Controls, and Human-Machine Interface technical area; and leverage cross-cutting capabilities while minimizing duplication of effort. The combined simulation environment and suite of models are identified as the TRANSFORM tool. The critical elements of this effort include (1) defining a standardized, common simulation environment that can be applied throughout the Advanced Reactors Technology program; (2) developing a library of baseline component modules that can be assembled into full plant models using available geometry, design, and thermal-hydraulic data; (3) defining modeling conventions for interconnecting component models; and (4) establishing user interfaces and support tools to facilitate simulation development (i.e., configuration and parameterization), execution, and results display and capture.« less

Design and Analysis of Mirror Modules for IXO and Beyond

NASA Technical Reports Server (NTRS)

McClelland, Ryan S.; Powell, Cory; Saha, Timo T.; Zhang, William W.

2011-01-01

Advancements in X-ray astronomy demand thin, light, and closely packed thin optics which lend themselves to segmentation of the annular mirrors and, in turn, a modular approach to the mirror design. The functionality requirements of such a mirror module are well understood. A baseline modular concept for the proposed International X-Ray Observatory (IXO) Flight Mirror Assembly (FMA) consisting of 14,000 glass mirror segments divided into 60 modules was developed and extensively analyzed. Through this development, our understanding of module loads, mirror stress, thermal performance, and gravity distortion have greatly progressed. The latest progress in each of these areas is discussed herein. Gravity distortion during horizontal X-ray testing and on-orbit thermal performance have proved especially difficult design challenges. In light of these challenges, fundamental trades in modular X-ray mirror design have been performed. Future directions in module X-ray mirror design are explored including the development of a 1.8 m diameter FMA utilizing smaller mirror modules. The effect of module size on mirror stress, module self-weight distortion, thermal control, and range of segment sizes required is explored with advantages demonstrated from smaller module size in most cases.

Technology advancement of the electrochemical CO2 concentrating process

NASA Technical Reports Server (NTRS)

Schubert, F. H.; Heppner, D. B.; Hallick, T. M.; Woods, R. R.

1979-01-01

Two multicell, liquid-cooled, advanced electrochemical depolarized carbon dioxide concentrator modules were fabricated. The cells utilized advanced, lightweight, plated anode current collectors, internal liquid cooling and lightweight cell frames. Both were designed to meet the carbon dioxide removal requirements of one-person, i.e., 1.0 kg/d (2.2 lb/d).

Summary of flat-plate solar array project documentation. Abstracts of published documents, 1975 to June 1982

NASA Technical Reports Server (NTRS)

1982-01-01

Technologies that will enable the private sector to manufacture and widely use photovoltaic systems for the generation of electricity in residential, commercial, industrial, and government applications at a cost per watt that is competitive with other means is investigated. Silicon refinement processes, advanced silicon sheet growth techniques, solar cell development, encapsulation, automated fabrication process technology, advanced module/array design, and module/array test and evaluation techniques are developed.

Study and design of cryogenic propellant acquisition systems. Volume 1: Design studies

NASA Technical Reports Server (NTRS)

Burge, G. W.; Blackmon, J. B.

1973-01-01

An in-depth study and selection of practical propellant surface tension acquisition system designs for two specific future cryogenic space vehicles, an advanced cryogenic space shuttle auxiliary propulsion system and an advanced space propulsion module is reported. A supporting laboratory scale experimental program was also conducted to provide design information critical to concept finalization and selection. Designs using localized pressure isolated surface tension screen devices were selected for each application and preliminary designs were generated. Based on these designs, large scale acquisition prototype hardware was designed and fabricated to be compatible with available NASA-MSFC feed system hardware.

Advanced Artificial Intelligence Technology Testbed

NASA Technical Reports Server (NTRS)

Anken, Craig S.

1993-01-01

The Advanced Artificial Intelligence Technology Testbed (AAITT) is a laboratory testbed for the design, analysis, integration, evaluation, and exercising of large-scale, complex, software systems, composed of both knowledge-based and conventional components. The AAITT assists its users in the following ways: configuring various problem-solving application suites; observing and measuring the behavior of these applications and the interactions between their constituent modules; gathering and analyzing statistics about the occurrence of key events; and flexibly and quickly altering the interaction of modules within the applications for further study.

Design of a small molecule against an oncogenic noncoding RNA.

PubMed

Velagapudi, Sai Pradeep; Cameron, Michael D; Haga, Christopher L; Rosenberg, Laura H; Lafitte, Marie; Duckett, Derek R; Phinney, Donald G; Disney, Matthew D

2016-05-24

The design of precision, preclinical therapeutics from sequence is difficult, but advances in this area, particularly those focused on rational design, could quickly transform the sequence of disease-causing gene products into lead modalities. Herein, we describe the use of Inforna, a computational approach that enables the rational design of small molecules targeting RNA to quickly provide a potent modulator of oncogenic microRNA-96 (miR-96). We mined the secondary structure of primary microRNA-96 (pri-miR-96) hairpin precursor against a database of RNA motif-small molecule interactions, which identified modules that bound RNA motifs nearby and in the Drosha processing site. Precise linking of these modules together provided Targaprimir-96 (3), which selectively modulates miR-96 production in cancer cells and triggers apoptosis. Importantly, the compound is ineffective on healthy breast cells, and exogenous overexpression of pri-miR-96 reduced compound potency in breast cancer cells. Chemical Cross-Linking and Isolation by Pull-Down (Chem-CLIP), a small-molecule RNA target validation approach, shows that 3 directly engages pri-miR-96 in breast cancer cells. In vivo, 3 has a favorable pharmacokinetic profile and decreases tumor burden in a mouse model of triple-negative breast cancer. Thus, rational design can quickly produce precision, in vivo bioactive lead small molecules against hard-to-treat cancers by targeting oncogenic noncoding RNAs, advancing a disease-to-gene-to-drug paradigm.

Fashion Merchandising Module. An Advanced-Level Option for Distribution and Marketing. For the U.S.O.E. Occupational Cluster of 04.02 Apparel and Accessories Marketing.

ERIC Educational Resources Information Center

Clis, Pat; And Others

This instructional module on fashion merchandising is designed as a guide for secondary education teachers who are helping twelfth grade students develop occupational competency for entry-level positions in fashion-related jobs. An introductory section covers module goals, career opportunities and employment demands, administrative considerations,…

A co-designed equalization, modulation, and coding scheme

NASA Technical Reports Server (NTRS)

Peile, Robert E.

1992-01-01

The commercial impact and technical success of Trellis Coded Modulation seems to illustrate that, if Shannon's capacity is going to be neared, the modulation and coding of an analogue signal ought to be viewed as an integrated process. More recent work has focused on going beyond the gains obtained for Average White Gaussian Noise and has tried to combine the coding/modulation with adaptive equalization. The motive is to gain similar advances on less perfect or idealized channels.

Engineering Cell-Cell Signaling

PubMed Central

Milano, Daniel F.; Natividad, Robert J.; Asthagiri, Anand R.

2014-01-01

Juxtacrine cell-cell signaling mediated by the direct interaction of adjoining mammalian cells is arguably the mode of cell communication that is most recalcitrant to engineering. Overcoming this challenge is crucial for progress in biomedical applications, such as tissue engineering, regenerative medicine, immune system engineering and therapeutic design. Here, we describe the significant advances that have been made in developing synthetic platforms (materials and devices) and synthetic cells (cell surface engineering and synthetic gene circuits) to modulate juxtacrine cell-cell signaling. In addition, significant progress has been made in elucidating design rules and strategies to modulate juxtacrine signaling based on quantitative, engineering analysis of the mechanical and regulatory role of juxtacrine signals in the context of other cues and physical constraints in the microenvironment. These advances in engineering juxtacrine signaling lay a strong foundation for an integrative approach to utilizing synthetic cells, advanced ‘chassis’ and predictive modeling to engineer the form and function of living tissues. PMID:23856592

Exploring Graphic Design. A Short Course in Desktop Publishing.

ERIC Educational Resources Information Center

Stanley, MLG

This course in desktop publishing contains seven illustrated modules designed to meet the following objectives: (1) use a desktop publishing program to explore advanced topics in graphic design; (2) learn about typography and how to make design decisions on the use of typestyles; (3) learn basic principles in graphic communications and apply them…

Amorphous silicon photovoltaic manufacturing technology, phase 2A

NASA Astrophysics Data System (ADS)

Duran, G.; Mackamul, K.; Metcalf, D.

1995-01-01

Utility Power Group (UPG), and its lower-tier subcontractor, Advanced Photovoltaic Systems, Inc. (APS) have conducted efforts in developing their manufacturing lines. UPG has focused on the automation of encapsulation and termination processes developed in Phase 1. APS has focused on completion of the encapsulation and module design tasks, while continuing the process and quality control and automation projects. The goal is to produce 55 watt (stabilized) EP50 modules in a new facility. In the APS Trenton EUREKA manufacturing facility, APS has: (1) Developed high throughput lamination procedures; (2) Optimized existing module designs; (3) Developed new module designs for architectural applications; (4) Developed enhanced deposition parameter control; (5) Designed equipment required to manufacture new EUREKA modules developed during Phase II; (6) Improved uniformity of thin-film materials deposition; and (7) Improved the stabilized power output of the APS EP50 EUREKA module to 55 watts. In the APS Fairfield EUREKA manufacturing facility, APS has: (1) Introduced the new products developed under Phase 1 into the APS Fairfield EUREKA module production line; (2) Increased the extent of automation in the production line; (3) Introduced Statistical Process Control to the module production line; and (4) Transferred-progress made in the APS Trenton facility into the APS Fairfield facility.

BBU design of linear induction accelerator cells for radiography application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shang, C.C.; Chen, Y.J.; Gaporaso, G.J.

1997-05-06

There is an ongoing effort to develop accelerating modules for high-current electron accelerators for advanced radiography application. Accelerating modules with low beam-cavity coupling impedances along with gap designs with acceptable field stresses comprise a set of fundamental design criteria. We examine improved cell designs which have been developed for accelerator application in several radiographic operating regimes. We evaluate interaction impedances, analyze the effects of beam structure coupling on beam dynamics (beam break-up instability and corkscrew motion). We also provide estimates of coupling through interesting new high-gradient insulators and evaluate their potential future application in induction cells.

Advances in the Lightweight Air-Liquid Composite Heat Exchanger Development for Space Exploration Applications

NASA Technical Reports Server (NTRS)

Shin, E. Eugene; Johnston, J. Chris; Haas, Daniel

2011-01-01

An advanced, lightweight composite modular Air/Liquid (A/L) Heat Exchanger (HX) Prototype for potential space exploration thermal management applications was successfully designed, manufactured, and tested. This full-scale Prototype consisting of 19 modules, based on recommendations from its predecessor Engineering Development unit (EDU) but with improved thermal characteristics and manufacturability, was 11.2 % lighter than the EDU and achieves potentially a 42.7% weight reduction from the existing state-of-the-art metallic HX demonstrator. However, its higher pressure drop (0.58 psid vs. 0.16 psid of the metal HX) has to be mitigated by foam material optimizations and design modifications including a more systematic air channel design. Scalability of the Prototype design was validated experimentally by comparing manufacturability and performance between the 2-module coupon and the 19-module Prototype. The Prototype utilized the thermally conductive open-cell carbon foam material but with lower density and adopted a novel high-efficiency cooling system with significantly increased heat transfer contact surface areas, improved fabricability and manufacturability compared to the EDU. Even though the Prototype was required to meet both the thermal and the structural specifications, accomplishing the thermal requirement was a higher priority goal for this first version. Overall, the Prototype outperformed both the EDU and the corresponding metal HX, particularly in terms of specific heat transfer, but achieved 93.4% of the target. The next generation Prototype to achieve the specification target, 3,450W would need 24 core modules based on the simple scaling factor. The scale-up Prototype will weigh about 14.7 Kg vs. 21.6 Kg for the metal counterpart. The advancement of this lightweight composite HX development from the original feasibility test coupons to EDU to Prototype is discussed in this paper.

NOTE: An innovative phantom for quantitative and qualitative investigation of advanced x-ray imaging technologies

NASA Astrophysics Data System (ADS)

Chiarot, C. B.; Siewerdsen, J. H.; Haycocks, T.; Moseley, D. J.; Jaffray, D. A.

2005-11-01

Development, characterization, and quality assurance of advanced x-ray imaging technologies require phantoms that are quantitative and well suited to such modalities. This note reports on the design, construction, and use of an innovative phantom developed for advanced imaging technologies (e.g., multi-detector CT and the numerous applications of flat-panel detectors in dual-energy imaging, tomosynthesis, and cone-beam CT) in diagnostic and image-guided procedures. The design addresses shortcomings of existing phantoms by incorporating criteria satisfied by no other single phantom: (1) inserts are fully 3D—spherically symmetric rather than cylindrical; (2) modules are quantitative, presenting objects of known size and contrast for quality assurance and image quality investigation; (3) features are incorporated in ideal and semi-realistic (anthropomorphic) contexts; and (4) the phantom allows devices to be inserted and manipulated in an accessible module (right lung). The phantom consists of five primary modules: (1) head, featuring contrast-detail spheres approximate to brain lesions; (2) left lung, featuring contrast-detail spheres approximate to lung modules; (3) right lung, an accessible hull in which devices may be placed and manipulated; (4) liver, featuring conrast-detail spheres approximate to metastases; and (5) abdomen/pelvis, featuring simulated kidneys, colon, rectum, bladder, and prostate. The phantom represents a two-fold evolution in design philosophy—from 2D (cylindrically symmetric) to fully 3D, and from exclusively qualitative or quantitative to a design accommodating quantitative study within an anatomical context. It has proven a valuable tool in investigations throughout our institution, including low-dose CT, dual-energy radiography, and cone-beam CT for image-guided radiation therapy and surgery.

Annual report, October 1, 1978-September 30, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-03-01

This report covers the following areas: (1) PLT, (2) PDX, (3) smaller devices, (4) TFTR, (5) TFTR blanket module experiments, (6) engineering, (7) machine design and fabrication, and (8) advanced projects design and analysis, (9) design studies for new devices, (10) theory, (11) administration, and (12) graduate education. (MOW)

Meteorological Satellites (METSAT) and Earth Observing System (EOS) Advanced Microwave Sounding Unit-A (AMSU-A) Stress Analysis Report

NASA Technical Reports Server (NTRS)

Heffner, Robert

1996-01-01

Stress analysis of the primary structure of the Meteorological Satellites Project (METSAT) Advanced Microwave Sounding Units-A, A1 Module using static loads is presented. The structural margins of safety and natural frequency predictions for the METSAT design are reported.

ADVANCED UTILITY SIMULATION MODEL, MULTI-PERIOD MULTI-STATE MODULE DESIGN DOCUMENTATION (VERSION 1.0)

EPA Science Inventory

The report is one of 11 in a series describing the initial development of the Advanced Utility Simulation Model (AUSM) by the Universities Research Group on Energy (URGE) and its continued development by the Science Applications International Corporation (SAIC) research team. The...

GLOBECOM '86 - Global Telecommunications Conference, Houston, TX, Dec. 1-4, 1986, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Papers are presented on local area networks; formal methods for communication protocols; computer simulation of communication systems; spread spectrum and coded communications; tropical radio propagation; VLSI for communications; strategies for increasing software productivity; multiple access communications; advanced communication satellite technologies; and spread spectrum systems. Topics discussed include Space Station communication and tracking development and design; transmission networks; modulation; data communications; computer network protocols and performance; and coding and synchronization. Consideration is given to free space optical communications systems; VSAT communication networks; network topology design; advances in adaptive filtering echo cancellation and adaptive equalization; advanced signal processing for satellite communications; the elements, design, and analysis of fiber-optic networks; and advances in digital microwave systems.

Solar dynamic power for the Space Station

NASA Technical Reports Server (NTRS)

Archer, J. S.; Diamant, E. S.

1986-01-01

This paper describes a computer code which provides a significant advance in the systems analysis capabilities of solar dynamic power modules. While the code can be used to advantage in the preliminary analysis of terrestrial solar dynamic modules its real value lies in the adaptions which make it particularly useful for the conceptualization of optimized power modules for space applications. In particular, as illustrated in the paper, the code can be used to establish optimum values of concentrator diameter, concentrator surface roughness, concentrator rim angle and receiver aperture corresponding to the main heat cycle options - Organic Rankine and Brayton - and for certain receiver design options. The code can also be used to establish system sizing margins to account for the loss of reflectivity in orbit or the seasonal variation of insolation. By the simulation of the interactions among the major components of a solar dynamic module and through simplified formulations of the major thermal-optic-thermodynamic interactions the code adds a powerful, efficient and economic analytical tool to the repertory of techniques available for the design of advanced space power systems.

The Automated Array Assembly Task of the Low-cost Silicon Solar Array Project, Phase 2

NASA Technical Reports Server (NTRS)

Coleman, M. G.; Grenon, L.; Pastirik, E. M.; Pryor, R. A.; Sparks, T. G.

1978-01-01

An advanced process sequence for manufacturing high efficiency solar cells and modules in a cost-effective manner is discussed. Emphasis is on process simplicity and minimizing consumed materials. The process sequence incorporates texture etching, plasma processes for damage removal and patterning, ion implantation, low pressure silicon nitride deposition, and plated metal. A reliable module design is presented. Specific process step developments are given. A detailed cost analysis was performed to indicate future areas of fruitful cost reduction effort. Recommendations for advanced investigations are included.

Design of a small molecule against an oncogenic noncoding RNA

PubMed Central

Velagapudi, Sai Pradeep; Cameron, Michael D.; Haga, Christopher L.; Rosenberg, Laura H.; Lafitte, Marie; Duckett, Derek R.; Phinney, Donald G.; Disney, Matthew D.

2016-01-01

The design of precision, preclinical therapeutics from sequence is difficult, but advances in this area, particularly those focused on rational design, could quickly transform the sequence of disease-causing gene products into lead modalities. Herein, we describe the use of Inforna, a computational approach that enables the rational design of small molecules targeting RNA to quickly provide a potent modulator of oncogenic microRNA-96 (miR-96). We mined the secondary structure of primary microRNA-96 (pri-miR-96) hairpin precursor against a database of RNA motif–small molecule interactions, which identified modules that bound RNA motifs nearby and in the Drosha processing site. Precise linking of these modules together provided Targaprimir-96 (3), which selectively modulates miR-96 production in cancer cells and triggers apoptosis. Importantly, the compound is ineffective on healthy breast cells, and exogenous overexpression of pri-miR-96 reduced compound potency in breast cancer cells. Chemical Cross-Linking and Isolation by Pull-Down (Chem-CLIP), a small-molecule RNA target validation approach, shows that 3 directly engages pri-miR-96 in breast cancer cells. In vivo, 3 has a favorable pharmacokinetic profile and decreases tumor burden in a mouse model of triple-negative breast cancer. Thus, rational design can quickly produce precision, in vivo bioactive lead small molecules against hard-to-treat cancers by targeting oncogenic noncoding RNAs, advancing a disease-to-gene-to-drug paradigm. PMID:27170187

Advanced Computing Technologies for Rocket Engine Propulsion Systems: Object-Oriented Design with C++

NASA Technical Reports Server (NTRS)

Bekele, Gete

2002-01-01

This document explores the use of advanced computer technologies with an emphasis on object-oriented design to be applied in the development of software for a rocket engine to improve vehicle safety and reliability. The primary focus is on phase one of this project, the smart start sequence module. The objectives are: 1) To use current sound software engineering practices, object-orientation; 2) To improve on software development time, maintenance, execution and management; 3) To provide an alternate design choice for control, implementation, and performance.

Advanced Distributed Simulation Technology Advanced Rotary Wing Aircraft. System/Segment Specification. Volume 1. Simulation System Module

DTIC Science & Technology

1994-03-31

overhead water sprinklers in enclosed personnel areas not already protected by existing facility fire suppression systems. Sprinkler systems shall not...facilitate future changes and updates to remain current with the application aircraft. 3.4.4 Availabilit . The ARWA SS shall be designed and constructed to

Conceptual spacecraft systems design and synthesis

NASA Technical Reports Server (NTRS)

Wright, R. L.; Deryder, D. D.; Ferebee, M. J., Jr.

1984-01-01

An interactive systems design and synthesis is performed on future spacecraft concepts using the Interactive Design and Evaluation of Advanced Systems (IDEAS) computer-aided design and analysis system. The capabilities and advantages of the systems-oriented interactive computer-aided design and analysis system are described. The synthesis of both large antenna and space station concepts, and space station evolutionary growth designs is demonstrated. The IDEAS program provides the user with both an interactive graphics and an interactive computing capability which consists of over 40 multidisciplinary synthesis and analysis modules. Thus, the user can create, analyze, and conduct parametric studies and modify earth-orbiting spacecraft designs (space stations, large antennas or platforms, and technologically advanced spacecraft) at an interactive terminal with relative ease. The IDEAS approach is useful during the conceptual design phase of advanced space missions when a multiplicity of parameters and concepts must be analyzed and evaluated in a cost-effective and timely manner.

Fault tolerant software modules for SIFT

NASA Technical Reports Server (NTRS)

Hecht, M.; Hecht, H.

1982-01-01

The implementation of software fault tolerance is investigated for critical modules of the Software Implemented Fault Tolerance (SIFT) operating system to support the computational and reliability requirements of advanced fly by wire transport aircraft. Fault tolerant designs generated for the error reported and global executive are examined. A description of the alternate routines, implementation requirements, and software validation are included.

Computer-Managed Instruction: Development and Evaluation of Student Skill Modules to Reduce Training Time.

ERIC Educational Resources Information Center

McCombs, Barbara L.; And Others

The Computer Managed Instruction (CMI) Student Skills Project was developed and evaluated within the context of the Air Force Advanced Instructional System (AIS), with student study skill modules designed as short packages to be assigned near the beginning of any military technical training course; strategies or procedures included were expected…

THE USE OF CHEMICALS AS HERBICIDES. AGRICULTURAL CHEMICALS TECHNOLOGY, NUMBER 6.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. Center for Vocational and Technical Education.

DEVELOPED BY A NATIONAL TASK FORCE ON THE BASIS OF STATE STUDIES, THIS MODULE IS ONE OF A SERIES DESIGNED TO ASSIST TEACHERS IN PREPARING POST-SECONDARY STUDENTS FOR ENTRY AND ADVANCEMENT IN AGRICULTURAL CHEMICAL OCCUPATIONS. THE SPECIFIC OBJECTIVES OF THIS MODULE ARE TO DEVELOP ABILITIES NECESSARY FOR OCCUPATIONS CONCERNED WITH CHEMICAL WEED…

Design and evaluation of basic standard encryption algorithm modules using nanosized complementary metal oxide semiconductor molecular circuits

NASA Astrophysics Data System (ADS)

Masoumi, Massoud; Raissi, Farshid; Ahmadian, Mahmoud; Keshavarzi, Parviz

2006-01-01

We are proposing that the recently proposed semiconductor-nanowire-molecular architecture (CMOL) is an optimum platform to realize encryption algorithms. The basic modules for the advanced encryption standard algorithm (Rijndael) have been designed using CMOL architecture. The performance of this design has been evaluated with respect to chip area and speed. It is observed that CMOL provides considerable improvement over implementation with regular CMOS architecture even with a 20% defect rate. Pseudo-optimum gate placement and routing are provided for Rijndael building blocks and the possibility of designing high speed, attack tolerant and long key encryptions are discussed.

NCC: A Multidisciplinary Design/Analysis Tool for Combustion Systems

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey; Quealy, Angela

1999-01-01

A multi-disciplinary design/analysis tool for combustion systems is critical for optimizing the low-emission, high-performance combustor design process. Based on discussions between NASA Lewis Research Center and the jet engine companies, an industry-government team was formed in early 1995 to develop the National Combustion Code (NCC), which is an integrated system of computer codes for the design and analysis of combustion systems. NCC has advanced features that address the need to meet designer's requirements such as "assured accuracy", "fast turnaround", and "acceptable cost". The NCC development team is comprised of Allison Engine Company (Allison), CFD Research Corporation (CFDRC), GE Aircraft Engines (GEAE), NASA Lewis Research Center (LeRC), and Pratt & Whitney (P&W). This development team operates under the guidance of the NCC steering committee. The "unstructured mesh" capability and "parallel computing" are fundamental features of NCC from its inception. The NCC system is composed of a set of "elements" which includes grid generator, main flow solver, turbulence module, turbulence and chemistry interaction module, chemistry module, spray module, radiation heat transfer module, data visualization module, and a post-processor for evaluating engine performance parameters. Each element may have contributions from several team members. Such a multi-source multi-element system needs to be integrated in a way that facilitates inter-module data communication, flexibility in module selection, and ease of integration.

Interactive systems design and synthesis of future spacecraft concepts

NASA Technical Reports Server (NTRS)

Wright, R. L.; Deryder, D. D.; Ferebee, M. J., Jr.

1984-01-01

An interactive systems design and synthesis is performed on future spacecraft concepts using the Interactive Design and Evaluation of Advanced spacecraft (IDEAS) computer-aided design and analysis system. The capabilities and advantages of the systems-oriented interactive computer-aided design and analysis system are described. The synthesis of both large antenna and space station concepts, and space station evolutionary growth is demonstrated. The IDEAS program provides the user with both an interactive graphics and an interactive computing capability which consists of over 40 multidisciplinary synthesis and analysis modules. Thus, the user can create, analyze and conduct parametric studies and modify Earth-orbiting spacecraft designs (space stations, large antennas or platforms, and technologically advanced spacecraft) at an interactive terminal with relative ease. The IDEAS approach is useful during the conceptual design phase of advanced space missions when a multiplicity of parameters and concepts must be analyzed and evaluated in a cost-effective and timely manner.

High-throughput manufacturing of thin-film CdS/CdTe photovoltaic modules. Annual subcontract report, 16 November 1994--15 November 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandwisch, D.W.

1997-02-01

The objectives of this subcontract are to advance Solar Cells, Inc.`s (SCI`s) photovoltaic manufacturing technologies, reduce module production costs, increase module performance, and provide the groundwork for SCI to expand its commercial production capacities. Activities during the second year of the program concentrated on process development, equipment design and testing, quality assurance, and ES and H programs. These efforts broadly addressed the issues of the manufacturing process for producing thin-film monolithic CdS/CdTe photovoltaic modules.

Soil Transport Implement

NASA Technical Reports Server (NTRS)

Dixon, William; Fan, William; Lloyd, Joey; Pham, Nam-Anh; Stevens, Michael

1988-01-01

The design of the Soil Transport Implement (STI) for SKITTER is presented. The purpose of STI is to provide a protective layer of lunar soil for the lunar modules. The objective is to cover the lunar module with a layer of soil approximately two meters thick within a two week period. The amount of soil required to cover the module is roughly 77 dump truck loads or three million earth pounds. A spinning disk is employed to accomplish its task. STI is an autonomous, teleoperated system. The design incorporates the latest advances in composite materials and high strength, light weight alloys to achieve a high strength to weight ratio. The preliminary design should only be used to assess the feasibility of employing a spinning wheel as a soil transport implement. A mathematical model of the spinning wheel was used to evaluate the performance of this design.

Integrated Electronic Warfare System Advanced Development Model (ADM); Appendix 26 - Signal Sorter (SS) Supervisor Design Specification & Flow Diagrams.

DTIC Science & Technology

1977-10-01

These modules make up a multi-task priority real - time operating system in which each of the functions of the Supervisor is performed by one or more tasks. The Initialization module performs the initialization of the Supervisor software and hardware including the Input Buffer, the FIFO, and the Track Correlator This module is used both at initial program load time and upon receipt of a SC Initialization Command.

Innovative manufacturing technologies for low-cost, high efficiency PERC-based PV modules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yelundur, Vijay

2017-04-19

The goal this project was to accelerate the deployment of innovative solar cell and module technologies that reduce the cost of PERC-based modules to best-in-class. New module integration technology was to be used to reduce the cost and reliance on conventional silver bus bar pastes and enhance cell efficiency. On the cell manufacturing front, the cost of PERC solar cells was to be reduced by introducing advanced metallization approaches to increase cell efficiency. These advancements will be combined with process optimization to target cell efficiencies in the range of 21 to 21.5%. This project will also explore the viability ofmore » a bifacial PERC solar cell design to enable cost savings through the use of thin silicon wafers. This project was terminated on 4/30/17 after four months of activity due financial challenges facing the recipient.« less

Bioregenerative Life Support System Research as part of the DLR EDEN Initiative

NASA Astrophysics Data System (ADS)

Bamsey, Matthew; Schubert, Daniel; Zabel, Paul; Poulet, Lucie; Zeidler, Conrad

In 2011, the DLR Institute of Space Systems launched a research initiative called EDEN - Evolution and Design of Environmentally-closed Nutrition-Sources. The research initiative focuses on bioregenerative life support systems, especially greenhouse modules, and technologies for future crewed vehicles. The EDEN initiative comprises several projects with respect to space research, ground testing and spin-offs. In 2014, EDEN’s new laboratory officially opened. This new biological cleanroom laboratory comprises several plant growth chambers incorporating a number of novel controlled environment agriculture technologies. This laboratory will be the nucleus for a variety of plant cultivation experiments within closed environments. The utilized technologies are being advanced using the pull of space technology and include such items as stacked growth systems, PAR-specific LEDs, intracanopy lighting, aeroponic nutrient delivery systems and ion-selective nutrient sensors. The driver of maximizing biomass output per unit volume and energy has much application in future bioregenerative life support systems but can also provide benefit terrestrially. The EDEN laboratory also includes several specially constructed chambers for advancing models addressing the interaction between bioregenerative and physical-chemical life support systems. The EDEN team is presently developing designs for containerized greenhouse modules. One module is planned for deployment to the German Antarctic Station, Neumayer III. The shipping container based system will provide supplementation to the overwintering crew’s diet, provide psychological benefit while at the same time advancing the technology and operational readiness of harsh environment plant production systems. In addition to hardware development, the EDEN team has participated in several early phase designs such as for the ESA Greenhouse Module for Space System and for large-scale vertical farming. These studies often utilize the Institute of Space Systems Concurrent Engineering Facility.

Earth Observing System (EOS)/Advanced Microwave Sounding Unit-A (AMSU-A) Stress Analysis Report, A1 Module. Addendum 1

NASA Technical Reports Server (NTRS)

Ely, W.

1996-01-01

This addendum reports the structural margins of safety and natural frequency predictions for the design following the EOS AMSU-A1 Mechanical/Structural Subsystem Critical Design Review (CDR), based on a new and more refined finite element model.

Ultra-Reliable Digital Avionics (URDA) processor

NASA Astrophysics Data System (ADS)

Branstetter, Reagan; Ruszczyk, William; Miville, Frank

1994-10-01

Texas Instruments Incorporated (TI) developed the URDA processor design under contract with the U.S. Air Force Wright Laboratory and the U.S. Army Night Vision and Electro-Sensors Directorate. TI's approach couples advanced packaging solutions with advanced integrated circuit (IC) technology to provide a high-performance (200 MIPS/800 MFLOPS) modular avionics processor module for a wide range of avionics applications. TI's processor design integrates two Ada-programmable, URDA basic processor modules (BPM's) with a JIAWG-compatible PiBus and TMBus on a single F-22 common integrated processor-compatible form-factor SEM-E avionics card. A separate, high-speed (25-MWord/second 32-bit word) input/output bus is provided for sensor data. Each BPM provides a peak throughput of 100 MIPS scalar concurrent with 400-MFLOPS vector processing in a removable multichip module (MCM) mounted to a liquid-flowthrough (LFT) core and interfacing to a processor interface module printed wiring board (PWB). Commercial RISC technology coupled with TI's advanced bipolar complementary metal oxide semiconductor (BiCMOS) application specific integrated circuit (ASIC) and silicon-on-silicon packaging technologies are used to achieve the high performance in a miniaturized package. A Mips R4000-family reduced instruction set computer (RISC) processor and a TI 100-MHz BiCMOS vector coprocessor (VCP) ASIC provide, respectively, the 100 MIPS of a scalar processor throughput and 400 MFLOPS of vector processing throughput for each BPM. The TI Aladdim ASIC chipset was developed on the TI Aladdin Program under contract with the U.S. Army Communications and Electronics Command and was sponsored by the Advanced Research Projects Agency with technical direction from the U.S. Army Night Vision and Electro-Sensors Directorate.

Silicon Wafer Advanced Packaging (SWAP). Multichip Module (MCM) Foundry Study. Version 2

DTIC Science & Technology

1991-04-08

Next Layer Dielectric Spacing - Additional Metal Thickness Impact on Dielectric Uniformity/Adhiesion. The first step in .!Ie EPerimental design would be... design CAM - computer aided manufacturing CAE - computer aided engineering CALCE - computer aided life cycle engineering center CARMA - computer aided...expansion 5 j- CVD - chemical vapor deposition J . ..- j DA - design automation J , DEC - Digital Equipment Corporation --- DFT - design for testability

Lunar landing and launch facilities and operations

NASA Technical Reports Server (NTRS)

1988-01-01

A preliminary design of a lunar landing and launch facility for a Phase 3 lunar base is formulated. A single multipurpose vehicle for the lunar module is assumed. Three traffic levels are envisioned: 6, 12, and 24 landings/launches per year. The facility is broken down into nine major design items. A conceptual description of each of these items is included. Preliminary sizes, capacities, and/or other relevant design data for some of these items are obtained. A quonset hut tent-like structure constructed of aluminum rods and aluminized mylar panels is proposed. This structure is used to provide a constant thermal environment for the lunar modules. A structural design and thermal analysis is presented. Two independent designs for a bridge crane to unload/load heavy cargo from the lunar module are included. Preliminary investigations into cryogenic propellant storage and handling, landing/launch guidance and control, and lunar module maintenance requirements are performed. Also, an initial study into advanced concepts for application to Phase 4 or 5 lunar bases has been completed in a report on capturing, condensing, and recycling the exhaust plume from a lunar launch.

Development of an Advanced Animal Habitat for Spaceflight

NASA Technical Reports Server (NTRS)

Baer, L.; Vasques, M.; Martwick, F.; Hines, M.; Grindeland, R. E.

1994-01-01

It is necessary to fly a group-housed animals for many Life Science spaceflight studies. Currently, group-housed rodents are flown aboard the shuttle in the Animal Enclosure Module (AEM). Although the AEM has been used successfully for a number of flights, it has significant limitations in the number of animals it can accommodate, limited flight duration, passive temperature control and limited in flight data acquisition capability. An Advanced Animal Habitat (AAH) is being developed, which can be flown on the shuttle middeck, both spacelab and spacehab shuttle payload modules, and the space station. The AAH is designed to house 12 rats or 30 mice for up to 30 days. The AAH will have active temperature control, a window mechanism to facilitate video monitoring/recording of the animals, and biotelemetry capabilities. In addition, the design will permit access to the animals for experimental manipulations in space. The AAH can be refitted to experiment-specific requirements as needed. In initial 7-day hardware tests 12 male rats and 10 female mice show no adverse affects with respect to final body and organ weights as compared to vivarium. controls. The Advanced Animal Habitat will provide the science community opportunities to perform a greater variety of studies for longer duration in the microgravity environment than the current Animal Enclosure Module.

Design of multi-mission chemical propulsion modules for planetary orbiters. Volume 1: Summary report

NASA Technical Reports Server (NTRS)

1975-01-01

Results are presented of a conceptual design and feasibility study of chemical propulsion stages that can serve as modular propulsion units, with little or no modification, on a variety of planetary orbit missions, including orbiters of Mercury, Saturn, and Uranus. Planetary spacecraft of existing design or currently under development, viz., spacecraft of the Pioneer and Mariner families, are assumed as payload vehicles. Thus, operating requirements of spin-stabilized and 3-axis stabilized spacecraft have to be met by the respective propulsion module designs. As launch vehicle for these missions the Shuttle orbiter and interplanetary injection stage, or Tug, plus solid-propellant kick motor was assumed. Accommodation constraints and interfaces involving the payloads and the launch vehicle are considered in the propulsion module design. The applicability and performance advantages were evaluated of the space-storable high-energy bipropellants. The incentive for using this advanced propulsion technology on planetary missions is the much greater performance potential when orbit insertion velocities in excess of 4 km/sec are required, as in the Mercury orbiter. Design analyses and performance tradeoffs regarding earth-storable versus space-storable propulsion systems are included. Cost and development schedules of multi-mission versus custom-designed propulsion modules are examined.

Technology Advancements for Active Remote Sensing of Carbon Dioxide from Space using the ASCENDS CarbonHawk Experiment Simulator

NASA Astrophysics Data System (ADS)

Obland, M. D.; Nehrir, A. R.; Liu, Z.; Chen, S.; Campbell, J. F.; Lin, B.; Kooi, S. A.; Fan, T. F.; Choi, Y.; Plant, J.; Yang, M. M.; Browell, E. V.; Harrison, F. W.; Meadows, B.; Dobler, J. T.; Zaccheo, T. S.

2015-12-01

This work describes advances in critical lidar technologies and techniques developed as part of the ASCENDS CarbonHawk Experiment Simulator (ACES) system for measuring atmospheric column carbon dioxide (CO2) mixing ratios in support of the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The ACES design demonstrates advancements in: (1) enhanced power-aperture product through the use and operation of multiple co-aligned laser transmitters and a multi-aperture telescope design; (2) high-efficiency, high-power Erbium-Doped Fiber Amplifiers (EDFAs); (3) high-bandwidth, low-noise HgCdTe detector and transimpedence amplifier (TIA) subsystem capable of long-duration operation; and (4) advanced algorithms for cloud and aerosol discrimination. The ACES instrument, an Intensity-Modulated Continuous-Wave (IM-CW) lidar, was designed for high-altitude aircraft operations and can be directly applied to space instrumentation to meet the ASCENDS mission requirements. Specifically, the lidar simultaneously transmits three IM-CW laser beams from the high power EDFAs operating near 1571 nm. The outgoing laser beams are aligned to the field of view of three fiber-coupled 17.8-cm diameter telescopes, and the backscattered light collected by the same three telescopes is sent to the detector/TIA subsystem, which has a bandwidth of 4.9 MHz and operates service-free with a tactical Dewar and cryocooler. The electronic bandwidth is only slightly higher than 1 MHz, effectively limiting the noise level. Two key laser modulation approaches are being tested to significantly mitigate the effects of thin clouds on the retrieved CO2 column amounts. This work provides an over view of these technologies, the modulation approaches, and results from recent test flights.

Technology Advancements for Active Remote Sensing of Carbon Dioxide From Space using the ASCENDS CarbonHawk Experiment Simulator

NASA Astrophysics Data System (ADS)

Obland, M. D.; Liu, Z.; Campbell, J. F.; Lin, B.; Kooi, S. A.; Carrion, W.; Hicks, J.; Fan, T. F.; Nehrir, A. R.; Browell, E. V.; Meadows, B.; Davis, K. J.

2016-12-01

This work describes advances in critical lidar technologies and techniques developed as part of the ASCENDS CarbonHawk Experiment Simulator (ACES) system for measuring atmospheric column carbon dioxide (CO2) mixing ratios in support of the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The ACES design demonstrates advancements in: (1) enhanced power-aperture product through the use and operation of multiple co-aligned laser transmitters and a multi-aperture telescope design; (2) high-efficiency, high-power Erbium-Doped Fiber Amplifiers (EDFAs); (3) high-bandwidth, low-noise HgCdTe detector and transimpedence amplifier (TIA) subsystem capable of long-duration operation; and (4) advanced algorithms for cloud and aerosol discrimination. The ACES instrument, an Intensity-Modulated Continuous-Wave (IM-CW) lidar, was designed for high-altitude aircraft operations and can be directly applied to space instrumentation to meet the ASCENDS mission requirements. Specifically, the lidar simultaneously transmits three IM-CW laser beams from the high power EDFAs operating near 1571 nm. The outgoing laser beams are aligned to the field of view of three fiber-coupled 17.8-cm diameter telescopes, and the backscattered light collected by the same three telescopes is sent to the detector/TIA subsystem, which has a bandwidth of 4.9 MHz and operates service-free with a tactical Dewar and cryocooler. The electronic bandwidth is only slightly higher than 1 MHz, effectively limiting the noise level. Two key laser modulation approaches are being tested to significantly mitigate the effects of thin clouds on the retrieved CO2 column amounts. This work provides an over view of these technologies, the modulation approaches, and results from recent test flights during the Atmospheric Carbon and Transport - America (ACT-America) Earth Venture Suborbital flight campaign.

Space station structures development

NASA Technical Reports Server (NTRS)

Teller, V. B.

1986-01-01

A study of three interrelated tasks focusing on deployable Space Station truss structures is discussed. Task 1, the development of an alternate deployment system for linear truss, resulted in the preliminary design of an in-space reloadable linear motor deployer. Task 2, advanced composites deployable truss development, resulted in the testing and evaluation of composite materials for struts used in a deployable linear truss. Task 3, assembly of structures in space/erectable structures, resulted in the preliminary design of Space Station pressurized module support structures. An independent, redundant support system was developed for the common United States modules.

Mars Equipment Transport System

NASA Technical Reports Server (NTRS)

Sorrells, Cindy; Geiger, Michelle; Ohanlon, Sean; Pieloch, Stuart; Brogan, Nick

1993-01-01

Mechanical Engineering Senior Design Project 1 (ME4182) is a part of the NASA/University Advanced Design Program. Under this program, NASA allocates money and resources to students to be used in design work for a specified topic. The current topic is the exploration and colonization of Mars. The specific area in which we are to work is the transportation of the modules in which astronauts will live while on Mars. NASA is concerned about the weight of the module transferring system, as the shipping cost to Mars is quite expensive. NASA has specified that the weight of the system is to be minimized in order to reduce the shipping costs.

Environmental Systems Test Stand

NASA Astrophysics Data System (ADS)

Barta, D.; Young, J.; Ewert, M.; Lee, S.; Wells, P.; Fortson, R.; Castillo, J.

A test stand has been developed for the evaluation of prototype lighting, environmental control and crop cultivation technologies for plant production within an advanced life support system. Design of the test stand was based on preliminary designs of the center growth bay of the Biomass Production Chamber, one of several modules of the Bioregenerative Planetary Life Support Systems Test Complex (BIO- Plex). It consists of two controlled-environment shelves, each with 4.7 m2 of area for crop growth (150 cm width, 315 cm length). There are two chilled water loops, one for operation at conventional temperatures (5-10C) for air temperature and humidity control and one for operation at higher temperatures (15-50C) for waste heat acquisition and heating. Modular light boxes, utilizing either air-cooled or water- jacketed HPS lamps, have been developed. This modular design will allow for easy replacement of new lighting technologies within the light banks. An advanced data acquisition and control system has been developed utilizing localized, networked- based data acquisition modules and programmed with object-based control software.

Orbit Transfer Rocket Engine Technology Program: Advanced engine study, task D.1/D.3

NASA Technical Reports Server (NTRS)

Martinez, A.; Erickson, C.; Hines, B.

1986-01-01

Concepts for space maintainability of OTV engines were examined. An engine design was developed which was driven by space maintenance requirements and by a failure mode and effects (FME) analysis. Modularity within the engine was shown to offer cost benefits and improved space maintenance capabilities. Space operable disconnects were conceptualized for both engine change-out and for module replacement. Through FME mitigation the modules were conceptualized to contain the least reliable and most often replaced engine components. A preliminary space maintenance plan was developed around a controls and condition monitoring system using advanced sensors, controls, and condition monitoring concepts. A complete engine layout was prepared satisfying current vehicle requirements and utilizing projected component advanced technologies. A technology plan for developing the required technology was assembled.

Garrett solar Brayton engine/generator status

NASA Astrophysics Data System (ADS)

Anson, B.

1982-07-01

The solar advanced gas turbine (SAGT-1) is being developed by the Garrett Turbine Engine Company, for use in a Brayton cycle power conversion module. The engine is derived from the advanced gas turbine (AGT101) now being developd by Garrett and Ford Motor Company for automotive use. The SAGT Program is presently funded for the design, fabrication and test of one engine at Garrett's Phoenix facility. The engine when mated with a solar receiver is called a power conversion module (PCU). The PCU is scheduled to be tested on JPL's test bed concentrator under a follow on phase of the program. Approximately 20 kw of electrical power will be generated.

Broadband, Spectrally Flat, Graphene-based Terahertz Modulators.

PubMed

Shi, Fenghua; Chen, Yihang; Han, Peng; Tassin, Philippe

2015-12-02

Advances in the efficient manipulation of terahertz waves are crucial for the further development of terahertz technology, promising applications in many diverse areas, such as biotechnology and spectroscopy, to name just a few. Due to its exceptional electronic and optical properties, graphene is a good candidate for terahertz electro-absorption modulators. However, graphene-based modulators demonstrated to date are limited in bandwidth due to Fabry-Perot oscillations in the modulators' substrate. Here, a novel method is demonstrated to design electrically controlled graphene-based modulators that can achieve broadband and spectrally flat modulation of terahertz beams. In our design, a graphene layer is sandwiched between a dielectric and a slightly doped substrate on a metal reflector. It is shown that the spectral dependence of the electric field intensity at the graphene layer can be dramatically modified by optimizing the structural parameters of the device. In this way, the electric field intensity can be spectrally flat and even compensate for the dispersion of the graphene conductivity, resulting in almost invariant absorption in a wide frequency range. Modulation depths up to 76% can be achieved within a fractional operational bandwidth of over 55%. It is expected that our modulator designs will enable the use of terahertz technology in applications requiring broadband operation. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Study of the collector/heat pipe cooled externally configured thermionic diode

NASA Technical Reports Server (NTRS)

1973-01-01

A collector/heat pipe cooled, externally configured (heated) thermionic diode module was designed for use in a laboratory test to demonstrate the applicability of this concept as the fuel element/converter module of an in-core thermionic electric power source. During the course of the program, this module evolved from a simple experimental mock-up into an advanced unit which was more reactor prototypical. Detailed analysis of all diode components led to their engineering design, fabrication, and assembly, with the exception of the collector/heat pipe. While several designs of high power annular wicked heat pipes were fabricated and tested, each exhibited unexpected performance difficulties. It was concluded that the basic cause of these problems was the formation of crud which interfered with the liquid flow in the annular passage of the evaporator region.

Lewis Research Center battery overview

NASA Technical Reports Server (NTRS)

Odonnell, Patricia

1993-01-01

The topics covered are presented in viewgraph form and include the following: the Advanced Communications Technology Satellite; the Space Station Freedom (SSF) photovoltaic power module division; Ni/H2 battery and cell design; individual pressure vessel (IPV) nickel-hydrogen cell testing SSF support; the LeRC Electrochemical Technology Branch; improved design IPV nickel-hydrogen cells; advanced technology for IPV nickel-hydrogen flight cells; a lightweight nickel-hydrogen cell; bipolar nickel-hydrogen battery development and technology; aerospace nickel-metal hydride cells; the NASA Sodium-Sulfur Cell Technology Flight Experiment; and the lithium-carbon dioxide battery thermodynamic model.

Spoked-ring microcavities: enabling seamless integration of nanophotonics in unmodified advanced CMOS microelectronics chips

NASA Astrophysics Data System (ADS)

Wade, Mark T.; Shainline, Jeffrey M.; Orcutt, Jason S.; Ram, Rajeev J.; Stojanovic, Vladimir; Popovic, Milos A.

2014-03-01

We present the spoked-ring microcavity, a nanophotonic building block enabling energy-efficient, active photonics in unmodified, advanced CMOS microelectronics processes. The cavity is realized in the IBM 45nm SOI CMOS process - the same process used to make many commercially available microprocessors including the IBM Power7 and Sony Playstation 3 processors. In advanced SOI CMOS processes, no partial etch steps and no vertical junctions are available, which limits the types of optical cavities that can be used for active nanophotonics. To enable efficient active devices with no process modifications, we designed a novel spoked-ring microcavity which is fully compatible with the constraints of the process. As a modulator, the device leverages the sub-100nm lithography resolution of the process to create radially extending p-n junctions, providing high optical fill factor depletion-mode modulation and thereby eliminating the need for a vertical junction. The device is made entirely in the transistor active layer, low-loss crystalline silicon, which eliminates the need for a partial etch commonly used to create ridge cavities. In this work, we present the full optical and electrical design of the cavity including rigorous mode solver and FDTD simulations to design the Qlimiting electrical contacts and the coupling/excitation. We address the layout of active photonics within the mask set of a standard advanced CMOS process and show that high-performance photonic devices can be seamlessly monolithically integrated alongside electronics on the same chip. The present designs enable monolithically integrated optoelectronic transceivers on a single advanced CMOS chip, without requiring any process changes, enabling the penetration of photonics into the microprocessor.

Proceedings of the Flat-Plate Solar Array Project Research Forum on the Design of Flat-Plate Photovoltaic Arrays for Central Stations

NASA Technical Reports Server (NTRS)

1983-01-01

The Flat Plate Solar Array Project, focuses on advancing technologies relevant to the design and construction of megawatt level central station systems. Photovoltaic modules and arrays for flat plate central station or other large scale electric power production facilities require the establishment of a technical base that resolves design issues and results in practical and cost effective configurations. Design, qualification and maintenance issues related to central station arrays derived from the engineering and operating experiences of early applications and parallel laboratory reserch activities are investigated. Technical issues are examined from the viewpoint of the utility engineer, architect/engineer and laboratory researcher. Topics on optimum source circuit designs, module insulation design for high system voltages, array safety, structural interface design, measurements, and array operation and maintenance are discussed.

Design and evaluation of potentiometric principles for bladder volume monitoring: a preliminary study.

PubMed

Chen, Shih-Ching; Hsieh, Tsung-Hsun; Fan, Wen-Jia; Lai, Chien-Hung; Chen, Chun-Lung; Wei, Wei-Feng; Peng, Chih-Wei

2015-06-01

Recent advances in microelectronics and wireless transmission technology have led to the development of various implantable sensors for real-time monitoring of bladder conditions. Although various sensing approaches for monitoring bladder conditions were reported, most such sensors have remained at the laboratory stage due to the existence of vital drawbacks. In the present study, we explored a new concept for monitoring the bladder capacity on the basis of potentiometric principles. A prototype of a potentiometer module was designed and fabricated and integrated with a commercial wireless transmission module and power unit. A series of in vitro pig bladder experiments was conducted to determine the best design parameters for implementing the prototype potentiometric device and to prove its feasibility. We successfully implemented the potentiometric module in a pig bladder model in vitro, and the error of the accuracy of bladder volume detection was <±3%. Although the proposed potentiometric device was built using a commercial wireless module, the design principles and animal experience gathered from this research can serve as a basis for developing new implantable bladder sensors in the future.

Broadband metasurface holograms: toward complete phase and amplitude engineering

PubMed Central

Wang, Qiu; Zhang, Xueqian; Xu, Yuehong; Gu, Jianqiang; Li, Yanfeng; Tian, Zhen; Singh, Ranjan; Zhang, Shuang; Han, Jiaguang; Zhang, Weili

2016-01-01

As a revolutionary three-dimensional imaging technique, holography has attracted wide attention for its ability to photographically record a light field. However, traditional phase-only or amplitude-only modulation holograms have limited image quality and resolution to reappear both amplitude and phase information required of the objects. Recent advances in metasurfaces have shown tremendous opportunities for using a planar design of artificial meta-atoms to shape the wave front of light by optimal control of both its phase and amplitude. Inspired by the concept of designer metasurfaces, we demonstrate a novel amplitude-phase modulation hologram with simultaneous five-level amplitude modulation and eight-level phase modulation. Such a design approach seeks to turn the perceived disadvantages of the traditional phase or amplitude holograms, and thus enable enhanced performance in resolution, homogeneity of amplitude distribution, precision, and signal-to-noise ratio. In particular, the unique holographic approach exhibits broadband characteristics. The method introduced here delivers more degrees of freedom, and allows for encoding highly complex information into designer metasurfaces, thus having the potential to drive next-generation technological breakthroughs in holography. PMID:27615519

Broadband metasurface holograms: toward complete phase and amplitude engineering.

PubMed

Wang, Qiu; Zhang, Xueqian; Xu, Yuehong; Gu, Jianqiang; Li, Yanfeng; Tian, Zhen; Singh, Ranjan; Zhang, Shuang; Han, Jiaguang; Zhang, Weili

2016-09-12

As a revolutionary three-dimensional imaging technique, holography has attracted wide attention for its ability to photographically record a light field. However, traditional phase-only or amplitude-only modulation holograms have limited image quality and resolution to reappear both amplitude and phase information required of the objects. Recent advances in metasurfaces have shown tremendous opportunities for using a planar design of artificial meta-atoms to shape the wave front of light by optimal control of both its phase and amplitude. Inspired by the concept of designer metasurfaces, we demonstrate a novel amplitude-phase modulation hologram with simultaneous five-level amplitude modulation and eight-level phase modulation. Such a design approach seeks to turn the perceived disadvantages of the traditional phase or amplitude holograms, and thus enable enhanced performance in resolution, homogeneity of amplitude distribution, precision, and signal-to-noise ratio. In particular, the unique holographic approach exhibits broadband characteristics. The method introduced here delivers more degrees of freedom, and allows for encoding highly complex information into designer metasurfaces, thus having the potential to drive next-generation technological breakthroughs in holography.

The Understanding by Design Guide to Advanced Concepts in Creating and Reviewing Units

ERIC Educational Resources Information Center

McTighe, Jay; Wiggins, Grant

2012-01-01

Regardless of your stage at implementing the design tools and using the improved template for Understanding by Design[R] (UbD), this companion to "The UbD Guide to Creating High-Quality Units" is essential for taking your work to a higher plane. This volume features a set of hands-on modules containing worksheets, models, and self-assessments that…

Advanced Solid State Lighting for AES Deep Space Hab Project

NASA Technical Reports Server (NTRS)

Holbert, Eirik

2015-01-01

The advanced Solid State Lighting (SSL) assemblies augmented 2nd generation modules under development for the Advanced Exploration Systems Deep Space Habitat in using color therapy to synchronize crew circadian rhythms. Current RGB LED technology does not produce sufficient brightness to adequately address general lighting in addition to color therapy. The intent is to address both through a mix of white and RGB LEDs designing for fully addressable alertness/relaxation levels as well as more dramatic circadian shifts.

Recent advance in the design of small molecular modulators of estrogen-related receptors.

PubMed

Lu, Xiaoyun; Peng, Lijie; Lv, Man; ding, Ke

2012-01-01

The estrogen-related receptors (ERRs), comprising ERRα, ERRβ and ERRγ, are the members of the nuclear receptor superfamily, which have been functionally implicated in estrogen signal pathway in various patterns. However, no natural ligand of ERRs has been identified to data, so identification of the synthetic modulators (inverse agonist and agonist) of ERRs would be highly effective in the treatment of estrogen-related pathologies, such as diabetes, breast cancer and osteoporosis. This review summarizes the structures and biological functions of ERR subtypes, and the progress in designing the small molecular modulators of ERRs as well as the detailed description of available co-crystal structures of the LBD of ERRs in three distinct states: unligand, inverse agonist bound, and agonist bound.

Silicon photonics plasma-modulators with advanced transmission line design.

PubMed

Merget, Florian; Azadeh, Saeed Sharif; Mueller, Juliana; Shen, Bin; Nezhad, Maziar P; Hauck, Johannes; Witzens, Jeremy

2013-08-26

We have investigated two novel concepts for the design of transmission lines in travelling wave Mach-Zehnder interferometer based Silicon Photonics depletion modulators overcoming the analog bandwidth limitations arising from cross-talk between signal lines in push-pull modulators and reducing the linear losses of the transmission lines. We experimentally validate the concepts and demonstrate an E/O -3 dBe bandwidth of 16 GHz with a 4V drive voltage (in dual drive configuration) and 8.8 dB on-chip insertion losses. Significant bandwidth improvements result from suppression of cross-talk. An additional bandwidth enhancement of ~11% results from a reduction of resistive transmission line losses. Frequency dependent loss models for loaded transmission lines and E/O bandwidth modeling are fully verified.

Resonant Enhanced Modulators

DTIC Science & Technology

2004-05-01

Lepore, M. H. Kwakernaak, H. Mohseni, G. A. Pajer, G. Griffel , D. Bechtle, A. F. Ulmer, Z. A. Shellenbarger, H. An, I. Adesida, S. Rommel, J-W...Advanced nanofabrication and advanced process development Giora Griffel – Ring resonator concept Daniel W. Bechtle – RF electrode design University of...conducted in glass microspheres by Giora Griffel (then at Polytechnic University) and other workers. Extremely high quality factors (Q’s) could be

Dynamic Analysis of Hammer Mechanism "Twin Hammer" of Impact Wrench

NASA Astrophysics Data System (ADS)

Konečný, M.; Slavík, J.

This paper describes function of the hammer mechanism "Twin hammer" the impact wrench, calculation of dynamic forces exerted on the mechanism and determining the contact pressures between the parts of the mechanism. The modelling of parts was performed in system Pro ENGINEER—standard. The simulation and finding dynamic forces was performed in advanced module Pro ENGINEER—mechanism design and finding contacts pressures in modul Pro ENGENEER—mechanica.

Thermally Stabilized Transmit/Receive Modules

NASA Technical Reports Server (NTRS)

Hoffman, James; DelCastillo, Linda; Miller, Jennifer; Birur, Gaj

2011-01-01

RF-hybrid technologies enable smaller packaging and mass reduction in radar instruments, especially for subsystems with dense electronics, such as electronically steered arrays. We are designing thermally stabilized RF-hybrid T/R modules using new materials for improved thermal performance of electronics. We are combining advanced substrate and housing materials with a thermal reservoir material, and develop new packaging techniques to significantly improve thermal-cycling reliability and performance stability over temperature.

Conceptual design of an on-board optical processor with components

NASA Technical Reports Server (NTRS)

Walsh, J. R.; Shackelford, R. G.

1977-01-01

The specification of components for a spacecraft on-board optical processor was investigated. A space oriented application of optical data processing and the investigation of certain aspects of optical correlators were examined. The investigation confirmed that real-time optical processing has made significant advances over the past few years, but that there are still critical components which will require further development for use in an on-board optical processor. The devices evaluated were the coherent light valve, the readout optical modulator, the liquid crystal modulator, and the image forming light modulator.

Development with quasi-bipolar Horizon{reg_sign} technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craven, W.B.

1997-12-01

Electrosource Inc. (ELSI) is now in production with an Electric Vehicle (EV) battery based on fundamental advances in materials design, manufacturing processes and well understood lead-acid electrochemistry. The production 12V-85Ah module is rated at 45 Whr/kg, 223 W/kg and 400 C/3 cycles. Production test modules have achieved over 50 Whr/kg and 500 cycles. Chrysler has chosen the Electrosource Horizon Battery for their EV Minivan that will be in production next year. Design flexibility has led to a Hybrid electric vehicle battery as well as SLI, UPS and portable power.

Research Studies on Advanced Optical Module/Head Designs for Optical Disk Recording Devices

NASA Technical Reports Server (NTRS)

Burke, James J.; Seery, Bernard D.

1993-01-01

The Annual Report of the Optical Data Storage Center of the University of Arizona is presented. Summary reports on continuing projects are presented. Research areas include: magneto-optic media, optical heads, and signal processing.

High throughput manufacturing of thin-film CdTe photovoltaic modules. Annual subcontract report, 16 November 1993--15 November 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandwisch, D W

1995-11-01

This report describes work performed by Solar Cells, Inc. (SCI), under a 3-year subcontract to advance SCI`s PV manufacturing technologies, reduce module production costs, increase module performance, and provide the groundwork for SCI to expand its commercial production capacities. SCI will meet these objectives in three phases by designing, debugging, and operating a 20-MW/year, automated, continuous PV manufacturing line that produces 60-cm {times} 120-cm thin-film CdTe PV modules. This report describes tasks completed under Phase 1 of the US Department of Energy`s PV Manufacturing Technology program.

Shrink-film microfluidic education modules: Complete devices within minutes

PubMed Central

Nguyen, Diep; McLane, Jolie; Lew, Valerie; Pegan, Jonathan; Khine, Michelle

2011-01-01

As advances in microfluidics continue to make contributions to diagnostics and life sciences, broader awareness of this expanding field becomes necessary. By leveraging low-cost microfabrication techniques that require no capital equipment or infrastructure, simple, accessible, and effective educational modules can be made available for a broad range of educational needs from middle school demonstrations to college laboratory classes. These modules demonstrate key microfluidic concepts such as diffusion and separation as well as “laboratory on-chip” applications including chemical reactions and biological assays. These modules are intended to provide an interdisciplinary hands-on experience, including chip design, fabrication of functional devices, and experiments at the microscale. Consequently, students will be able to conceptualize physics at small scales, gain experience in computer-aided design and microfabrication, and perform experiments—all in the context of addressing real-world challenges by making their own lab-on-chip devices. PMID:21799715

Shrink-film microfluidic education modules: Complete devices within minutes.

PubMed

Nguyen, Diep; McLane, Jolie; Lew, Valerie; Pegan, Jonathan; Khine, Michelle

2011-06-01

As advances in microfluidics continue to make contributions to diagnostics and life sciences, broader awareness of this expanding field becomes necessary. By leveraging low-cost microfabrication techniques that require no capital equipment or infrastructure, simple, accessible, and effective educational modules can be made available for a broad range of educational needs from middle school demonstrations to college laboratory classes. These modules demonstrate key microfluidic concepts such as diffusion and separation as well as "laboratory on-chip" applications including chemical reactions and biological assays. These modules are intended to provide an interdisciplinary hands-on experience, including chip design, fabrication of functional devices, and experiments at the microscale. Consequently, students will be able to conceptualize physics at small scales, gain experience in computer-aided design and microfabrication, and perform experiments-all in the context of addressing real-world challenges by making their own lab-on-chip devices.

Modular design of the LED vehicle projector headlamp system.

PubMed

Hsieh, Chi-Chang; Li, Yan-Huei; Hung, Chih-Ching

2013-07-20

A well designed headlamp for a vehicle lighting system is very important as it provides drivers with safe and comfortable driving conditions at night or in dark places. With the advances of the semiconductor technology, the LED has become the fourth generation lighting source in the auto industry. In this study, we will propose a LED vehicle projector headlamp system. This headlamp system contains several LED headlamp modules, and every module of it includes four components: focused LEDs, asymmetric metal-based plates, freeform surfaces, and condenser lenses. By optimizing the number of LED headlamp modules, the proposed LED vehicle projector headlamp system has only five LED headlamp modules. It not only provides the low-beam cutoff without a shield, but also meets the requirements of the ECE R112 regulation. Finally, a prototype of the LED vehicle projector headlamp system was assembled and fabricated to create the correct light pattern.

Making it easy to do the right thing in healthcare: Advancing improvement science education through accredited pan European higher education modules.

PubMed

MacRae, Rhoda; Rooney, Kevin D; Taylor, Alan; Ritters, Katrina; Sansoni, Julita; Lillo Crespo, Manuel; Skela-Savič, Brigita; O'Donnell, Barbara

2016-07-01

Numerous international policy drivers espouse the need to improve healthcare. The application of Improvement Science has the potential to restore the balance of healthcare and transform it to a more person-centred and quality improvement focussed system. However there is currently no accredited Improvement Science education offered routinely to healthcare students. This means that there are a huge number of healthcare professionals who do not have the conceptual or experiential skills to apply Improvement Science in everyday practise. This article describes how seven European Higher Education Institutions (HEIs) worked together to develop four evidence informed accredited inter-professional Improvement Science modules for under and postgraduate healthcare students. It outlines the way in which a Policy Delphi, a narrative literature review, a review of the competency and capability requirements for healthcare professionals to practise Improvement Science, and a mapping of current Improvement Science education informed the content of the modules. A contemporary consensus definition of Healthcare Improvement Science was developed. The four Improvement Science modules that have been designed are outlined. A framework to evaluate the impact modules have in practise has been developed and piloted. The authors argue that there is a clear need to advance healthcare Improvement Science education through incorporating evidence based accredited modules into healthcare professional education. They suggest that if Improvement Science education, that incorporates work based learning, becomes a staple part of the curricula in inter-professional education then it has real promise to improve the delivery, quality and design of healthcare. Copyright © 2016 Elsevier Ltd. All rights reserved.

Hybrid Analog/Digital Receiver

NASA Technical Reports Server (NTRS)

Brown, D. H.; Hurd, W. J.

1989-01-01

Advanced hybrid analog/digital receiver processes intermediate-frequency (IF) signals carrying digital data in form of phase modulation. Uses IF sampling and digital phase-locked loops to track carrier and subcarrier signals and to synchronize data symbols. Consists of three modules: IF assembly, signal-processing assembly, and test-signal assembly. Intended for use in Deep Space Network, but presumably basic design modified for such terrestrial uses as communications or laboratory instrumentation where signals weak and/or noise strong.

Design, analysis and test verification of advanced encapsulation systems

NASA Technical Reports Server (NTRS)

Garcia, A., III

1983-01-01

A preliminary reduced variable master was constructed for pressure loading. A study of cell thickness versus cell stress was completed. Work is continuing on encapsulation of qualification modules. A 4 ft x 4 ft 'credit card' construction laminate was made.

Design, analysis and test verification of advanced encapsulation systems

NASA Astrophysics Data System (ADS)

Garcia, A., III

1983-02-01

A preliminary reduced variable master was constructed for pressure loading. A study of cell thickness versus cell stress was completed. Work is continuing on encapsulation of qualification modules. A 4 ft x 4 ft 'credit card' construction laminate was made.

Research, development, and demonstration of lead-acid batteries for electric vehicle propulsion

NASA Astrophysics Data System (ADS)

1984-06-01

Research on electric motor vehicles is reported in the areas of active material utilization and active material integrity; design and fabrication of components, advanced cells, and modules; cell testing; and battery thermal management and electrolyte circulation subsystems.

Development of a 33 kV, 20 A long pulse converter modulator for high average power klystron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reghu, T.; Mandloi, V.; Shrivastava, Purushottam

Research, design, and development of high average power, long pulse modulators for the proposed Indian Spallation Neutron Source are underway at Raja Ramanna Centre for Advanced Technology. With this objective, a prototype of long pulse modulator capable of delivering 33 kV, 20 A at 5 Hz repetition rate has been designed and developed. Three Insulated Gate Bipolar Transistors (IGBT) based switching modules driving high frequency, high voltage transformers have been used to generate high voltage output. The IGBT based switching modules are shifted in phase by 120° with respect to each other. The switching frequency is 25 kHz. Pulses ofmore » 1.6 ms pulse width, 80 μs rise time, and 70 μs fall time have been achieved at the modulator output. A droop of ±0.6% is achieved using a simple segmented digital droop correction technique. The total fault energy transferred to the load during fault has been measured by conducting wire burn tests and is found to be within 3.5 J.« less

Design, analysis, and test verification of advanced encapsulation systems

NASA Technical Reports Server (NTRS)

Garcia, A.; Minning, C.

1981-01-01

Thermal, optical, structural, and electrical isolation analyses are decribed. Major factors in the design of terrestrial photovoltaic modules are discussed. Mechanical defects in the different layers of an encapsulation system, it was found, would strongly influence the minimum pottant thickness required for electrical isolation. Structural, optical, and electrical properties, a literature survey indicated, are hevily influenced by the presence of moisture. These items, identified as technology voids, are discussed. Analyses were based upon a 1.2 meter square module using 10.2 cm (4-inch) square cells placed 1.3 mm apart as shown in Figure 2-2. Sizing of the structural support member of a module was determined for a uniform, normal pressure load of 50 psf, corresponding to the pressure difference generated between the front and back surface of a module by a 100 mph wind. Thermal and optical calculations were performed for a wind velocity of 1 meter/sec parallel to the ground and for module tilt (relative to the local horizontal) of 37 deg. Placement of a module in a typical array field is illustrated.

Development of a 33 kV, 20 A long pulse converter modulator for high average power klystron

NASA Astrophysics Data System (ADS)

Reghu, T.; Mandloi, V.; Shrivastava, Purushottam

2014-05-01

Research, design, and development of high average power, long pulse modulators for the proposed Indian Spallation Neutron Source are underway at Raja Ramanna Centre for Advanced Technology. With this objective, a prototype of long pulse modulator capable of delivering 33 kV, 20 A at 5 Hz repetition rate has been designed and developed. Three Insulated Gate Bipolar Transistors (IGBT) based switching modules driving high frequency, high voltage transformers have been used to generate high voltage output. The IGBT based switching modules are shifted in phase by 120° with respect to each other. The switching frequency is 25 kHz. Pulses of 1.6 ms pulse width, 80 μs rise time, and 70 μs fall time have been achieved at the modulator output. A droop of ±0.6% is achieved using a simple segmented digital droop correction technique. The total fault energy transferred to the load during fault has been measured by conducting wire burn tests and is found to be within 3.5 J.

Design, analysis, and test verification of advanced encapsulation systems

NASA Astrophysics Data System (ADS)

Garcia, A.; Minning, C.

1981-11-01

Thermal, optical, structural, and electrical isolation analyses are decribed. Major factors in the design of terrestrial photovoltaic modules are discussed. Mechanical defects in the different layers of an encapsulation system, it was found, would strongly influence the minimum pottant thickness required for electrical isolation. Structural, optical, and electrical properties, a literature survey indicated, are hevily influenced by the presence of moisture. These items, identified as technology voids, are discussed. Analyses were based upon a 1.2 meter square module using 10.2 cm (4-inch) square cells placed 1.3 mm apart as shown in Figure 2-2. Sizing of the structural support member of a module was determined for a uniform, normal pressure load of 50 psf, corresponding to the pressure difference generated between the front and back surface of a module by a 100 mph wind. Thermal and optical calculations were performed for a wind velocity of 1 meter/sec parallel to the ground and for module tilt (relative to the local horizontal) of 37 deg. Placement of a module in a typical array field is illustrated.

Electrochemical Energy Storage for an Orbiting Space Station

NASA Technical Reports Server (NTRS)

Martin, R. E.

1981-01-01

The system weight of a multi hundred kilowatt fuel cell electrolysis cell energy storage system based upon alkaline electrochemical cell technology for use in a future orbiting space station in low Earth orbit (LEO) was studied. Preliminary system conceptual design, fuel cell module performance characteristics, subsystem and system weights, and overall system efficiency are identified. The impact of fuel cell module operating temperature and efficiency upon energy storage system weight is investigated. The weight of an advanced technology system featuring high strength filament wound reactant tanks and a fuel cell module employing lightweight graphite electrolyte reservoir plates is defined.

The FLECS expandable module concept for future space missions and an overall description on the material validation

NASA Astrophysics Data System (ADS)

Mileti, Sandro; Guarrera, Giuseppe; Marchetti, Mario; Ferrari, Giorgio; Nebiolo, Marco; Augello, Gerlando; Bitetti, Grazia; Carnà, Emiliano; Marranzini, Andrea; Mazza, Fabio

2006-07-01

The future space exploration missions aim to reduce the costs associated with design, fabrication and launch for ISS, Moon and Mars modules, while simultaneously increasing the useful volume. Flexible and inflatable structures offer many advantages over conventional structures for space applications. Principal among the advantages is the ability to package these structures into small volumes for launch. Design maturation and the development of advanced materials and fabrication processes have made the concept of an inflatable module achievable in the near future. The Multipurpose Expandable Module (FLECS) Project sponsored by ASI (Italian Space Agency) whose prime contractor is Alcatel Alenia Space Italia, links the conventional and traditional technology of modules with the innovative solutions of inflatable technology. This project emphasizes on demonstrating the capability in using inflatable technology on space structures aiming to substitute the conventional modules in future manned missions. FLECS has been designed using advanced textiles and films in order to guarantee the structural reliability necessary for the deployment and packaging configurations. A non-linear structural analysis has been conducted using several numerical codes that simulate the deployed structural characteristics achieving also the damping resistance during the packaging. All the materials used for the flexible parts have been selected through a series of mechanical tests in order to validate the more appropriate ones for the mission. The multi-layer pneumatic retention bladder and the intermediate restraint layer are composed of polymer sheets, ortho-fabrics and elastomers like polyurethanes. The External protection shield is configured using several layers of impact absorption materials and also several layers of space environment (UV, IR, atomic oxygen) protection materials such as Kapton, Mylar and Nextel. The validation of the fabrics, the films and the final prototype assembly are tested in the Space Environment Simulator (SAS), located in the SASLab laboratory of the Aerospace Engineering Department of the “La Sapienza” University of Rome.

Preprototype nitrogen supply subsystem development

NASA Technical Reports Server (NTRS)

Heppner, D. B.; Fort, J. H.; Schubert, F. H.

1982-01-01

The design and development of a test stand for the Nitrogen Generation Module (NGM) and a series of tests which verified its operation and performance capability are described. Over 900 hours of parametric testing were achieved. The results from this testing were then used to design an advanced NGM and a self contained, preprototype Nitrogen Supply Subsystem. The NGM consists of three major components: nitrogen generation module, pressure controller and hydrazine storage tank and ancillary components. The most important improvement is the elimination of all sealing surfaces, achieved with a total welded or brazed construction. Additionally, performance was improved by increasing hydrogen separating capability by 20% with no increase in overall packaging size.

Optical isolation based on space-time engineered asymmetric photonic band gaps

NASA Astrophysics Data System (ADS)

Chamanara, Nima; Taravati, Sajjad; Deck-Léger, Zoé-Lise; Caloz, Christophe

2017-10-01

Nonreciprocal electromagnetic devices play a crucial role in modern microwave and optical technologies. Conventional methods for realizing such systems are incompatible with integrated circuits. With recent advances in integrated photonics, the need for efficient on-chip magnetless nonreciprocal devices has become more pressing than ever. This paper leverages space-time engineered asymmetric photonic band gaps to generate optical isolation. It shows that a properly designed space-time modulated slab is highly reflective/transparent for opposite directions of propagation. The corresponding design is magnetless, accommodates low modulation frequencies, and can achieve very high isolation levels. An experimental proof of concept at microwave frequencies is provided.

Advanced Soldier Thermoelectric Power System for Power Generation from Battlefield Heat Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendricks, Terry J.; Hogan, Tim; Case, Eldon D.

2010-09-01

The U.S. military uses large amounts of fuel during deployments and battlefield operations. This project sought to develop a lightweight, small form-factor, soldier-portable advanced thermoelectric (TE) system prototype to recover and convert waste heat from various deployed military equipment (i.e., diesel generators/engines, incinerators, vehicles, and potentially mobile kitchens), with the ultimate purpose of producing power for soldier battery charging, advanced capacitor charging, and other battlefield power applications. The technical approach employed microchannel technology, a unique “power panel” approach to heat exchange/TE system integration, and newly-characterized LAST (lead-antimony-silver-telluride) and LASTT (lead-antimony-silver-tin-telluride) TE materials segmented with bismuth telluride TE materials in designingmore » a segmented-element TE power module and system. This project researched never-before-addressed system integration challenges (thermal expansion, thermal diffusion, electrical interconnection, thermal and electrical interfaces) of designing thin “power panels” consisting of alternating layers of thin, microchannel heat exchangers (hot and cold) sandwiching thin, segmented-element TE power generators. The TE properties, structurally properties, and thermal fatigue behavior of LAST and LASTT materials were developed and characterized such that the first segmented-element TE modules using LAST / LASTT materials were fabricated and tested at hot-side temperatures = 400 °C and cold-side temperatures = 40 °C. LAST / LASTT materials were successfully segmented with bismuth telluride and electrically interconnected with diffusion barrier materials and copper strapping within the module electrical circuit. A TE system design was developed to produce 1.5-1.6 kW of electrical energy using these new TE modules from the exhaust waste heat of 60-kW Tactical Quiet Generators as demonstration vehicles.« less

Recent advances in developing small molecules targeting RNA.

PubMed

Guan, Lirui; Disney, Matthew D

2012-01-20

RNAs are underexploited targets for small molecule drugs or chemical probes of function. This may be due, in part, to a fundamental lack of understanding of the types of small molecules that bind RNA specifically and the types of RNA motifs that specifically bind small molecules. In this review, we describe recent advances in the development and design of small molecules that bind to RNA and modulate function that aim to fill this void.

Optogenetics and pharmacogenetics: principles and applications.

PubMed

Jiang, Jingwei; Cui, Huxing; Rahmouni, Kamal

2017-12-01

Remote and selective spatiotemporal control of the activity of neurons to regulate behavior and physiological functions has been a long-sought goal in system neuroscience. Identification and subsequent bioengineering of light-sensitive ion channels (e.g., channelrhodopsins, halorhodopsin, and archaerhodopsins) from the bacteria have made it possible to use light to artificially modulate neuronal activity, namely optogenetics. Recent advance in genetics has also allowed development of novel pharmacological tools to selectively and remotely control neuronal activity using engineered G protein-coupled receptors, which can be activated by otherwise inert drug-like small molecules such as the designer receptors exclusively activated by designer drug, a form of chemogenetics. The cutting-edge optogenetics and pharmacogenetics are powerful tools in neuroscience that allow selective and bidirectional modulation of the activity of defined populations of neurons with unprecedented specificity. These novel toolboxes are enabling significant advances in deciphering how the nervous system works and its influence on various physiological processes in health and disease. Here, we discuss the fundamental elements of optogenetics and chemogenetics approaches and some of the applications that yielded significant advances in various areas of neuroscience and beyond. Copyright © 2017 the American Physiological Society.

Vapor Measurement System of Essential Oil Based on MOS Gas Sensors Driven with Advanced Temperature Modulation Technique

NASA Astrophysics Data System (ADS)

Sudarmaji, A.; Margiwiyatno, A.; Ediati, R.; Mustofa, A.

2018-05-01

The aroma/vapor of essential oils is complex compound which depends on the content of the gases and volatiles generated from essential oil. This paper describes a design of quick, simple, and low-cost static measurement system to acquire vapor profile of essential oil. The gases and volatiles are captured in a chamber by means of 9 MOS gas sensors which driven with advance temperature modulation technique. A PSoC CY8C28445-24PVXI based-interface unit is built to generate the modulation signal and acquire all sensor output into computer wirelessly via radio frequency serial communication using Digi International Inc., XBee (IEEE 802.15.4) through developed software under Visual.Net. The system was tested to measure 2 kinds of essential oil (Patchouli and Clove Oils) in 4 temperature modulations (without, 0.25 Hz, 1 Hz, and 4 Hz). A cycle measurement consists of reference and sample measurement sequentially which is set during 2 minutes in every 1 second respectively. It is found that the suitable modulation is 0,25Hz; 75%, and the results of Principle Component Analysis show that the system is able to distinguish clearly between Patchouli Oil and Clove Oil.

Space Launch System Co-Manifested Payload Options for Habitation

NASA Technical Reports Server (NTRS)

Smitherman, David

2015-01-01

The Space Launch System (SLS) has a co-manifested payload capability that will grow over time as the launch vehicle matures and planned upgrades are implemented. The final configuration is planned to be capable of inserting a payload greater than 10 metric tons (mt) into a trans-lunar injection trajectory along with the crew in the Orion capsule and its service module. The co-manifested payload is located below the Orion and its service module in a 10 m high fairing similar to the way the Saturn launch vehicle carried the lunar lander below the Apollo command and service modules. Various approaches that utilize this comanifested payload capability to build up infrastructure in deep space have been explored in support of future asteroid, lunar, and Mars mission scenarios. This paper reports on the findings of the Advanced Concepts Office study team at NASA Marshall Space Flight Center (MSFC) working with the Advanced Exploration Systems Program on the Exploration Augmentation Module Project. It includes some of the possible options for habitation in the co-manifested payload volume of the SLS. Findings include a set of module designs that can be developed in 10 mt increments to support these co-manifested payload missions along with a comparison of this approach to a large-module payload flight configuration for the SLS.

GENESIS 2: Advanced lunar outpost

NASA Technical Reports Server (NTRS)

Moore, Gary T.

1991-01-01

Advanced, second-generation lunar habitats for astronauts and mission specialists working on the Moon are investigated. The work was based on design constraints set forth in previous publications. Design recommendations are based on environmental response to the lunar environment, habitability, safety, near-term technology, replaceability and modularity, and suitability for NASA lunar research missions in the early 21st century. Scientists, engineers, and architects from NASA/JSC, Wisconsin aeronautical industry, and area universities gave technical input and offered critiques at design reviews throughout the process. The recommended design uses a lunar lava tube, with construction using a combination of Space Station Freedom-derived modules and lightweight Kevlar-laminate inflatables. The outpost includes research laboratories and biotron, crew quarters and support facility, mission control, health maintenance facility, and related areas for functional and psychological requirements. Furniture, specialized equipment, and lighting are included in the design analysis.

Overview of the NCC

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey

2001-01-01

A multi-disciplinary design/analysis tool for combustion systems is critical for optimizing the low-emission, high-performance combustor design process. Based on discussions between then NASA Lewis Research Center and the jet engine companies, an industry-government team was formed in early 1995 to develop the National Combustion Code (NCC), which is an integrated system of computer codes for the design and analysis of combustion systems. NCC has advanced features that address the need to meet designer's requirements such as "assured accuracy", "fast turnaround", and "acceptable cost". The NCC development team is comprised of Allison Engine Company (Allison), CFD Research Corporation (CFDRC), GE Aircraft Engines (GEAE), NASA Glenn Research Center (LeRC), and Pratt & Whitney (P&W). The "unstructured mesh" capability and "parallel computing" are fundamental features of NCC from its inception. The NCC system is composed of a set of "elements" which includes grid generator, main flow solver, turbulence module, turbulence and chemistry interaction module, chemistry module, spray module, radiation heat transfer module, data visualization module, and a post-processor for evaluating engine performance parameters. Each element may have contributions from several team members. Such a multi-source multi-element system needs to be integrated in a way that facilitates inter-module data communication, flexibility in module selection, and ease of integration. The development of the NCC beta version was essentially completed in June 1998. Technical details of the NCC elements are given in the Reference List. Elements such as the baseline flow solver, turbulence module, and the chemistry module, have been extensively validated; and their parallel performance on large-scale parallel systems has been evaluated and optimized. However the scalar PDF module and the Spray module, as well as their coupling with the baseline flow solver, were developed in a small-scale distributed computing environment. As a result, the validation of the NCC beta version as a whole was quite limited. Current effort has been focused on the validation of the integrated code and the evaluation/optimization of its overall performance on large-scale parallel systems.

The Advanced Technology Operations System: ATOS

NASA Technical Reports Server (NTRS)

Kaufeler, J.-F.; Laue, H. A.; Poulter, K.; Smith, H.

1993-01-01

Mission control systems supporting new space missions face ever-increasing requirements in terms of functionality, performance, reliability and efficiency. Modern data processing technology is providing the means to meet these requirements in new systems under development. During the past few years the European Space Operations Centre (ESOC) of the European Space Agency (ESA) has carried out a number of projects to demonstrate the feasibility of using advanced software technology, in particular, knowledge based systems, to support mission operations. A number of advances must be achieved before these techniques can be moved towards operational use in future missions, namely, integration of the applications into a single system framework and generalization of the applications so that they are mission independent. In order to achieve this goal, ESA initiated the Advanced Technology Operations System (ATOS) program, which will develop the infrastructure to support advanced software technology in mission operations, and provide applications modules to initially support: Mission Preparation, Mission Planning, Computer Assisted Operations, and Advanced Training. The first phase of the ATOS program is tasked with the goal of designing and prototyping the necessary system infrastructure to support the rest of the program. The major components of the ATOS architecture is presented. This architecture relies on the concept of a Mission Information Base (MIB) as the repository for all information and knowledge which will be used by the advanced application modules in future mission control systems. The MIB is being designed to exploit the latest in database and knowledge representation technology in an open and distributed system. In conclusion the technological and implementation challenges expected to be encountered, as well as the future plans and time scale of the project, are presented.

Advanced Bioinks for 3D Printing: A Materials Science Perspective.

PubMed

Chimene, David; Lennox, Kimberly K; Kaunas, Roland R; Gaharwar, Akhilesh K

2016-06-01

Advanced bioinks for 3D printing are rationally designed materials intended to improve the functionality of printed scaffolds outside the traditional paradigm of the "biofabrication window". While the biofabrication window paradigm necessitates compromise between suitability for fabrication and ability to accommodate encapsulated cells, recent developments in advanced bioinks have resulted in improved designs for a range of biofabrication platforms without this tradeoff. This has resulted in a new generation of bioinks with high print fidelity, shear-thinning characteristics, and crosslinked scaffolds with high mechanical strength, high cytocompatibility, and the ability to modulate cellular functions. In this review, we describe some of the promising strategies being pursued to achieve these goals, including multimaterial, interpenetrating network, nanocomposite, and supramolecular bioinks. We also provide an overview of current and emerging trends in advanced bioink synthesis and biofabrication, and evaluate the potential applications of these novel biomaterials to clinical use.

A white paper: Operational efficiency. New approaches to future propulsion systems

NASA Technical Reports Server (NTRS)

Rhodes, Russel; Wong, George

1991-01-01

Advanced launch systems for the next generation of space transportation systems (1995 to 2010) must deliver large payloads (125,000 to 500,000 lbs) to low earth orbit (LEO) at one tenth of today's cost, or 300 to 400 $/lb of payload. This cost represents an order of magnitude reduction from the Titan unmanned vehicle cost of delivering payload to orbit. To achieve this sizable reduction, the operations cost as well as the engine cost must both be lower than current engine system. The Advanced Launch System (ALS) is studying advanced engine designs, such as the Space Transportation Main Engine (STME), which has achieved notable reduction in cost. The results are presented of a current study wherein another level of cost reduction can be achieved by designing the propulsion module utilizing these advanced engines for enhanced operations efficiency and reduced operations cost.

Mineral Physics Educational Modules for Advanced Undergraduates and Graduate Students

NASA Astrophysics Data System (ADS)

Burnley, P. C.; Thomas, S.; Honn, D. K.

2011-12-01

We are assembling a group of web-based educational modules for a course entitled "Introduction to Mineral Physics". Although the modules are designed to function as part of a full semester course, each module will also be able to stand alone. The modules are targeted at entry level graduate students and advanced undergraduate students. Learning outcomes for the course are being developed in consultation with educators throughout the mineral physics community. Potential users include mineral physicists teaching "bricks and mortar" graduate classes at their own institutions, mineral physicists teaching graduate classes in a distance education setting, mineralogy teachers interested in including supplementary material in their undergraduate mineralogy class, undergraduates doing independent study projects and graduate students and colleagues in other subdisciplines who wish to brush up on mineral physics topics. The modules reside on the Science Education Resource Center at Carleton College web site in the On the Cutting Edge - Teaching Mineralogy collection. Links to the materials will be posted on the Consortium for Materials Properties Research in Earth Sciences website. The modules will be piloted in a graduate level distance education course in mineral physics taught from UNLV during the spring 2012 semester. This course and others like it can address the current problems faced by faculty in state universities where rising minimum enrollments are making it difficult to teach a suitable graduate course to incoming students.

Modules to enhance smart lighting education

NASA Astrophysics Data System (ADS)

Bunch, Robert M.; Joenathan, Charles; Connor, Kenneth; Chouikha, Mohamed

2012-10-01

Over the past several years there has been a rapid advancement in solid state lighting applications brought on by the development of high efficiency light emitting diodes. Development of lighting devices, systems and products that meet the demands of the future lighting marketplace requires workers from many disciplines including engineers, scientists, designers and architects. The National Science Foundation has recognized this fact and established the Smart Lighting Engineering Research Center that promotes research leading to smart lighting systems, partners with industry to enhance innovation and educates a diverse, world-class workforce. The lead institution is Rensselaer Polytechnic Institute with core partners Boston University and The University of New Mexico. Outreach partners include Howard University, Morgan State University, and Rose-Hulman Institute of Technology. Because of the multidisciplinary nature of advanced smart lighting systems workers often have little or no formal education in basic optics, lighting and illumination. This paper describes the initial stages of the development of self-contained and universally applicable educational modules that target essential optics topics needed for lighting applications. The modules are intended to be easily incorporated into new and existing courses by a variety of educators and/or to be used in a series of stand-alone, asynchronous training exercises by new graduate students. The ultimate goal of this effort is to produce resources such as video lectures, video presentations of students-teaching-students, classroom activities, assessment tools, student research projects and laboratories integrated into learning modules. Sample modules and resources will be highlighted. Other outreach activities such as plans for coursework, undergraduate research, design projects, and high school enrichment programs will be discussed.

solar thermal power systems advanced solar thermal technology project, advanced subsystems development

NASA Technical Reports Server (NTRS)

1979-01-01

The preliminary design for a prototype small (20 kWe) solar thermal electric generating unit was completed, consisting of several subsystems. The concentrator and the receiver collect solar energy and a thermal buffer storage with a transport system is used to provide a partially smoothed heat input to the Stirling engine. A fossil-fuel combustor is included in the receiver designs to permit operation with partial or no solar insolation (hybrid). The engine converts the heat input into mechanical action that powers a generator. To obtain electric power on a large scale, multiple solar modules will be required to operate in parallel. The small solar electric power plant used as a baseline design will provide electricity at remote sites and small communities.

Study of repeater technology for advanced multifunctional communications satellites

NASA Technical Reports Server (NTRS)

1972-01-01

Investigations are presented concerning design concepts and implementation approaches for the satellite communication repeater subsystems of advanced multifunctional satellites. In such systems the important concepts are the use of multiple antenna beams, repeater switching (routing), and efficient spectrum utilization through frequency reuse. An information base on these techniques was developed and tradeoff analyses were made of repeater design concepts, with the work design taken in a broad sense to include modulation beam coverage patterns. There were five major areas of study: requirements analysis and processing; study of interbeam interference in multibeam systems; characterization of multiple-beam switching repeaters; estimation of repeater weight and power for a number of alternatives; and tradeoff analyses based on these weight and power data.

Plasma chamber testing of advanced photovoltaic solar array coupons

NASA Technical Reports Server (NTRS)

Hillard, G. Barry

1994-01-01

The solar array module plasma interactions experiment is a space shuttle experiment designed to investigate and quantify the high voltage plasma interactions. One of the objectives of the experiment is to test the performance of the Advanced Photovoltaic Solar Array (APSA). The material properties of array blanket are also studied as electric insulators for APSA arrays in high voltage conditions. Three twelve cell prototype coupons of silicon cells were constructed and tested in a space simulation chamber.

A Profile of Defense Manufacturing Costs and Enabling Technologies

DTIC Science & Technology

1992-01-01

RECEIVE MODULE F Missiles 75mm Cadmium Zinc Telluride F 94 GHZ MILLIMETER WAVE TRANSCEIVER F COMPOSITES FOR PASSIVE THERMAL MANAGEMENT F COMPOSITES FOR... PASSIVE THERMAL MANAGEMENT F Design standards for surface mount devices I Electro-optic Components Advanced Manufacturing PrDcess I FIBER OPTIC

Diaphragm Stirling engine heat-actuated heat pump development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ackermann, R.A.; Swenson, P.

1981-01-01

The objective of this program is to develop and demonstrate the performance of a diaphragm Stirling engine heat-actuated heat pump power module. The power module, consisting of a free displacer, resonant Stirling engine, hydraulic transmission, and resonant Rankine refrigerant (F-22) compressor, embodies several innovative concepts in free-piston Stirling engine heat pump design that will advance the state of the art of this technology. Progress is reported in three areas of the program. First, a compressor/engine matching analysis and a stability analysis have shown that the power module, which is representative of a two-degree-of-freedom resonant system, will operate stably over themore » full range of heat pump conditions. Second, a compressor design has evolved that has met criteria for performance and cost; and third, tests employing a hydraulic simulator test rig has shown that the transmission losses are less than had been predicted, and that properly designed and fabricated diaphragms can attain long life.« less

KSC-01PP1402

NASA Image and Video Library

2001-07-27

KENNEDY SPACE CENTER, Fla. -- On Launch Pad 39A, two Hitchhiker Experiments Advancing Technology (HEAT) payloads are loaded onto Discovery’s port adapter beam in the payload bay. At left is the Space Experiment Module, an educational initiative to increase educational access to space. The canister contains up to 10 small, enclosed modules that contain separate, passive experiments designed and constructed by students. Many of the experiments will study the growing characteristics of plants subjected to the space environment. At right is the Get Away Special canister containing the Alkali Metal Thermal-to-Electric Converter (AMTEC), designed for efficient conversion of heat into electrical energy. The HEAT payloads are flying on mission STS-105, scheduled to launch Aug. 9, 2001

Modular Isotopic Thermoelectric Generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, Alfred

1981-01-01

Advanced RTG concepts utilizing improved thermoelectric materials and converter concepts are under study at Fairchild for DOE. The design described here is based on DOE's newly developed radioisotope heat source, and on an improved silicon-germanium material and multicouple converter module under development at Syncal. Fairchild's assignment was to combine the above into an attractive power system for use in space, and to assess the specific power and other attributes of that design.

Shuttle wave experiments. [space plasma investigations: design and instrumentation

NASA Technical Reports Server (NTRS)

Calvert, W.

1976-01-01

Wave experiments on shuttle are needed to verify dispersion relations, to study nonlinear and exotic phenomena, to support other plasma experiments, and to test engineering designs. Techniques based on coherent detection and bistatic geometry are described. New instrumentation required to provide modules for a variety of missions and to incorporate advanced signal processing and control techniques is discussed. An experiment for Z to 0 coupling is included.

Segmented X-Ray Optics for Future Space Telescopes

NASA Technical Reports Server (NTRS)

McClelland, Ryan S.

2013-01-01

Lightweight and high resolution mirrors are needed for future space-based X-ray telescopes to achieve advances in high-energy astrophysics. The slumped glass mirror technology in development at NASA GSFC aims to build X-ray mirror modules with an area to mass ratio of approx.17 sq cm/kg at 1 keV and a resolution of 10 arc-sec Half Power Diameter (HPD) or better at an affordable cost. As the technology nears the performance requirements, additional engineering effort is needed to ensure the modules are compatible with space-flight. This paper describes Flight Mirror Assembly (FMA) designs for several X-ray astrophysics missions studied by NASA and defines generic driving requirements and subsequent verification tests necessary to advance technology readiness for mission implementation. The requirement to perform X-ray testing in a horizontal beam, based on the orientation of existing facilities, is particularly burdensome on the mirror technology, necessitating mechanical over-constraint of the mirror segments and stiffening of the modules in order to prevent self-weight deformation errors from dominating the measured performance. This requirement, in turn, drives the mass and complexity of the system while limiting the testable angular resolution. Design options for a vertical X-ray test facility alleviating these issues are explored. An alternate mirror and module design using kinematic constraint of the mirror segments, enabled by a vertical test facility, is proposed. The kinematic mounting concept has significant advantages including potential for higher angular resolution, simplified mirror integration, and relaxed thermal requirements. However, it presents new challenges including low vibration modes and imperfections in kinematic constraint. Implementation concepts overcoming these challenges are described along with preliminary test and analysis results demonstrating the feasibility of kinematically mounting slumped glass mirror segments.

COURSE OUTLINE FOR AGRICULTURAL SUPPLY - SALES AND SERVICE OCCUPATIONS.

ERIC Educational Resources Information Center

BECKER, WILLIAM; LINTNER, J.H.

TITLES OF MODULES, PURPOSES, TIME AND SUPPORTING EDUCATIONAL REQUIREMENTS, AND OPERATIONAL DETAILS OF A COURSE ARE GIVEN IN THIS PUBLICATION DESIGNED TO ASSIST STATE AND LOCAL VOCATIONAL EDUCATION LEADERS IN DEVELOPING PROGRAMS TO PREPARE HIGH SCHOOL STUDENTS FOR ENTRY AND ADVANCEMENT IN BUSINESSES WHICH SELL AGRICULTURAL SUPPLIES AND SERVICES TO…

Tools and Methods for Teaching Informatics at School: An Advanced Logo Course.

ERIC Educational Resources Information Center

Nikolov, Rumen

1992-01-01

Describes a course in educational informatics for preservice teachers and students in educational software development that emphasizes the use of LOGO, and summarizes course modules that cover tools and methods for teaching informatics, informatics curriculum design, introducing the basic notions of informatics, integrating informatics into the…

Systems design and comparative analysis of large antenna concepts

NASA Technical Reports Server (NTRS)

Garrett, L. B.; Ferebee, M. J., Jr.

1983-01-01

Conceptual designs are evaluated and comparative analyses conducted for several large antenna spacecraft for Land Mobile Satellite System (LMSS) communications missions. Structural configurations include trusses, hoop and column and radial rib. The study was conducted using the Interactive Design and Evaluation of Advanced Spacecraft (IDEAS) system. The current capabilities, development status, and near-term plans for the IDEAS system are reviewed. Overall capabilities are highlighted. IDEAS is an integrated system of computer-aided design and analysis software used to rapidly evaluate system concepts and technology needs for future advanced spacecraft such as large antennas, platforms, and space stations. The system was developed at Langley to meet a need for rapid, cost-effective, labor-saving approaches to the design and analysis of numerous missions and total spacecraft system options under consideration. IDEAS consists of about 40 technical modules efficient executive, data-base and file management software, and interactive graphics display capabilities.

The middleware architecture supports heterogeneous network systems for module-based personal robot system

NASA Astrophysics Data System (ADS)

Choo, Seongho; Li, Vitaly; Choi, Dong Hee; Jung, Gi Deck; Park, Hong Seong; Ryuh, Youngsun

2005-12-01

On developing the personal robot system presently, the internal architecture is every module those occupy separated functions are connected through heterogeneous network system. This module-based architecture supports specialization and division of labor at not only designing but also implementation, as an effect of this architecture, it can reduce developing times and costs for modules. Furthermore, because every module is connected among other modules through network systems, we can get easy integrations and synergy effect to apply advanced mutual functions by co-working some modules. In this architecture, one of the most important technologies is the network middleware that takes charge communications among each modules connected through heterogeneous networks systems. The network middleware acts as the human nerve system inside of personal robot system; it relays, transmits, and translates information appropriately between modules that are similar to human organizations. The network middleware supports various hardware platform, heterogeneous network systems (Ethernet, Wireless LAN, USB, IEEE 1394, CAN, CDMA-SMS, RS-232C). This paper discussed some mechanisms about our network middleware to intercommunication and routing among modules, methods for real-time data communication and fault-tolerant network service. There have designed and implemented a layered network middleware scheme, distributed routing management, network monitoring/notification technology on heterogeneous networks for these goals. The main theme is how to make routing information in our network middleware. Additionally, with this routing information table, we appended some features. Now we are designing, making a new version network middleware (we call 'OO M/W') that can support object-oriented operation, also are updating program sources itself for object-oriented architecture. It is lighter, faster, and can support more operation systems and heterogeneous network systems, but other general purposed middlewares like CORBA, UPnP, etc. can support only one network protocol or operating system.

The future of type 1 cannabinoid receptor allosteric ligands.

PubMed

Alaverdashvili, Mariam; Laprairie, Robert B

2018-02-01

Allosteric modulation of the type 1 cannabinoid receptor (CB1R) holds great therapeutic potential. This is because allosteric modulators do not possess intrinsic efficacy, but instead augment (positive allosteric modulation) or diminish (negative allosteric modulation) the receptor's response to endogenous ligand. Consequently, CB1R allosteric modulators have an effect ceiling which allows for the tempering of CB1R signaling without the desensitization, tolerance, dependence, and psychoactivity associated with orthosteric compounds. Pain, movement disorders, epilepsy, obesity are all potential therapeutic targets for CB1R allosteric modulation. Several challenges exist for the development of CB1R allosteric modulators, such as receptor subtype specificity, translation to in vivo systems, and mixed allosteric/agonist/inverse agonist activity. Despite these challenges, elucidation of crystal structures of CB1R and compound design based on structure-activity relationships will advance the field. In this review, we will cover recent progress for CB1R allosteric modulators and discuss the future promise of this research.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Incorporation of real-time component information using equipment condition assessment (ECA) through the developmentof enhanced risk monitors (ERM) for active components in advanced reactor (AR) and advanced small modular reactor (SMR) designs. We incorporate time-dependent failure probabilities from prognostic health management (PHM) systems to dynamically update the risk metric of interest. This information is used to augment data used for supervisory control and plant-wide coordination of multiple modules by providing the incremental risk incurred due to aging and demands placed on components that support mission requirements.

ATCA for Machines-- Advanced Telecommunications Computing Architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, R.S.; /SLAC

2008-04-22

The Advanced Telecommunications Computing Architecture is a new industry open standard for electronics instrument modules and shelves being evaluated for the International Linear Collider (ILC). It is the first industrial standard designed for High Availability (HA). ILC availability simulations have shown clearly that the capabilities of ATCA are needed in order to achieve acceptable integrated luminosity. The ATCA architecture looks attractive for beam instruments and detector applications as well. This paper provides an overview of ongoing R&D including application of HA principles to power electronics systems.

Advanced composites structural concepts and materials technologies for primary aircraft structures. Structural response and failure analysis: ISPAN modules users manual

NASA Technical Reports Server (NTRS)

Hairr, John W.; Huang, Jui-Ten; Ingram, J. Edward; Shah, Bharat M.

1992-01-01

The ISPAN Program (Interactive Stiffened Panel Analysis) is an interactive design tool that is intended to provide a means of performing simple and self contained preliminary analysis of aircraft primary structures made of composite materials. The program combines a series of modules with the finite element code DIAL as its backbone. Four ISPAN Modules were developed and are documented. These include: (1) flat stiffened panel; (2) curved stiffened panel; (3) flat tubular panel; and (4) curved geodesic panel. Users are instructed to input geometric and material properties, load information and types of analysis (linear, bifurcation buckling, or post-buckling) interactively. The program utilizing this information will generate finite element mesh and perform analysis. The output in the form of summary tables of stress or margins of safety, contour plots of loads or stress, and deflected shape plots may be generalized and used to evaluate specific design.

Sodium Based Heat Pipe Modules for Space Reactor Concepts: Stainless Steel SAFE-100 Core

NASA Technical Reports Server (NTRS)

Martin, James J.; Reid, Robert S.

2004-01-01

A heat pipe cooled reactor is one of several candidate reactor cores being considered for advanced space power and propulsion systems to support future space exploration applications. Long life heat pipe modules, with designs verified through a combination of theoretical analysis and experimental lifetime evaluations, would be necessary to establish the viability of any of these candidates, including the heat pipe reactor option. A hardware-based program was initiated to establish the infrastructure necessary to build heat pipe modules. This effort, initiated by Los Alamos National Laboratory and referred to as the Safe Affordable Fission Engine (SAFE) project, set out to fabricate and perform non-nuclear testing on a modular heat pipe reactor prototype that can provide 100 kilowatt from the core to an energy conversion system at 700 C. Prototypic heat pipe hardware was designed, fabricated, filled, closed-out and acceptance tested.

Progress towards an Optimization Methodology for Combustion-Driven Portable Thermoelectric Power Generation Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krishnan, Shankar; Karri, Naveen K.; Gogna, Pawan K.

2012-03-13

Enormous military and commercial interests exist in developing quiet, lightweight, and compact thermoelectric (TE) power generation systems. This paper investigates design integration and analysis of an advanced TE power generation system implementing JP-8 fueled combustion and thermal recuperation. Design and development of a portable TE power system using a JP-8 combustor as a high temperature heat source and optimal process flows depend on efficient heat generation, transfer, and recovery within the system are explored. Design optimization of the system required considering the combustion system efficiency and TE conversion efficiency simultaneously. The combustor performance and TE sub-system performance were coupled directlymore » through exhaust temperatures, fuel and air mass flow rates, heat exchanger performance, subsequent hot-side temperatures, and cold-side cooling techniques and temperatures. Systematic investigation of this system relied on accurate thermodynamic modeling of complex, high-temperature combustion processes concomitantly with detailed thermoelectric converter thermal/mechanical modeling. To this end, this work reports on design integration of systemlevel process flow simulations using commercial software CHEMCADTM with in-house thermoelectric converter and module optimization, and heat exchanger analyses using COMSOLTM software. High-performance, high-temperature TE materials and segmented TE element designs are incorporated in coupled design analyses to achieve predicted TE subsystem level conversion efficiencies exceeding 10%. These TE advances are integrated with a high performance microtechnology combustion reactor based on recent advances at the Pacific Northwest National Laboratory (PNNL). Predictions from this coupled simulation established a basis for optimal selection of fuel and air flow rates, thermoelectric module design and operating conditions, and microtechnology heat-exchanger design criteria. This paper will discuss this simulation process that leads directly to system efficiency power maps defining potentially available optimal system operating conditions and regimes. This coupled simulation approach enables pathways for integrated use of high-performance combustor components, high performance TE devices, and microtechnologies to produce a compact, lightweight, combustion driven TE power system prototype that operates on common fuels.« less

Advanced subsystems development

NASA Technical Reports Server (NTRS)

Livingston, F. R.

1978-01-01

The concept design for a small (less than 10 MWe) solar thermal electric generating plant was completed using projected 1985 technology. The systems requirements were defined and specified. The components, including an engineering prototype for one 15 kWe module of the generating plant, were conceptually designed. Significant features of the small solar thermal power plant were identified as the following: (1) 15 kWe Stirling-cycle engine/alternator with constant power output; (2) 10 meter point-focusing paraboloidal concentrator with cantilevered cellular glass reflecting panels; (3) primary heat pipe with 800 C output solar cavity receiver; (4) secondary heat pipe with molten salt thermal energy storage unit; (5) electric energy transport system; and (6) advanced battery energy storage capability.

Waste Receiving and Processing Facility Module 2A: Advanced Conceptual Design Report. Volume 3A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Objective of this document is to provide descriptions of all WRAP 2A feed streams, including physical and chemical attributes, and describe the pathway that was used to select data for volume estimates. WRAP 2A is being designed for nonthermal treatment of contact-handled mixed low-level waste Category 1 and 3. It is based on immobilization and encapsulation treatment using grout or polymer.

The Nuclear Energy Advanced Modeling and Simulation Safeguards and Separations Reprocessing Plant Toolkit

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCaskey, Alex; Billings, Jay Jay; de Almeida, Valmor F

2011-08-01

This report details the progress made in the development of the Reprocessing Plant Toolkit (RPTk) for the DOE Nuclear Energy Advanced Modeling and Simulation (NEAMS) program. RPTk is an ongoing development effort intended to provide users with an extensible, integrated, and scalable software framework for the modeling and simulation of spent nuclear fuel reprocessing plants by enabling the insertion and coupling of user-developed physicochemical modules of variable fidelity. The NEAMS Safeguards and Separations IPSC (SafeSeps) and the Enabling Computational Technologies (ECT) supporting program element have partnered to release an initial version of the RPTk with a focus on software usabilitymore » and utility. RPTk implements a data flow architecture that is the source of the system's extensibility and scalability. Data flows through physicochemical modules sequentially, with each module importing data, evolving it, and exporting the updated data to the next downstream module. This is accomplished through various architectural abstractions designed to give RPTk true plug-and-play capabilities. A simple application of this architecture, as well as RPTk data flow and evolution, is demonstrated in Section 6 with an application consisting of two coupled physicochemical modules. The remaining sections describe this ongoing work in full, from system vision and design inception to full implementation. Section 3 describes the relevant software development processes used by the RPTk development team. These processes allow the team to manage system complexity and ensure stakeholder satisfaction. This section also details the work done on the RPTk ``black box'' and ``white box'' models, with a special focus on the separation of concerns between the RPTk user interface and application runtime. Section 4 and 5 discuss that application runtime component in more detail, and describe the dependencies, behavior, and rigorous testing of its constituent components.« less

Hybrid plasmonic electro-optical absorption modulator based on epsilon-near-zero characteristics of ITO

NASA Astrophysics Data System (ADS)

Abdelatty, M. Y.; Badr, M. M.; Swillam, M. A.

2018-03-01

Using transparent conducting oxides (TCOs), like indium-tin-oxide (ITO), for optical modulation attracted research interest because of their epsilon-near-zero (ENZ) characteristics at telecom wavelengths. Utilizing indium-tin-oxide (ITO) in multilayer structure modulators, optical absorption of the active ITO layer can be electrically modulated over a large spectrum range. Although they show advances over common silicon electro-optical modulators (EOMs), they suffer from high insertion losses. To reduce insertion losses and device footprints without sacrificing bandwidth and modulation strength, slot waveguides are promising options because of their high optical confinement. In this paper, we present the study and the design of an electro-optical absorption modulator based on electrically tuning ITO carrier density inside a MOS structure. The device structure is based on dielectric slot waveguide with an ITO plasmonic waveguide modulation section. By changing the dimensions, the effective refractive indices for the slot mode and the off-sate mode of the plasmonic section can be matched. When applying electric field to the plasmonic section (on-state), carriers are generated at the ITO-dielectric interface that result in changing the layer where the electric field is confined from a transparent layer into a lossy layer. A finite difference time domain method with perfect matching layer (PML) absorbing boundary conditions is taken up to simulate and analyze this design. An extinction ratio of 2.3 dB is achieved for a 1-μm-short modulation section, at the telecommunications wavelength (1.55 μm). This EOM has advantages of simple design, easy fabrication, compact size, compatibility with existing silicon photonics platforms, as well as broadband performance.

Spacelab Accomplishments Forum 4

NASA Technical Reports Server (NTRS)

Emond, J. (Editor); Bennet, N. (Compiler); McCauley, D. (Compiler); Murphy, K. (Compiler); Baugher, Charles R. (Technical Monitor)

1999-01-01

The Spacelab Module, exposed platforms, and supporting instrumentation were designed and developed by the European Space Agency to house advanced experiments inside the Space Shuttle cargo bay. The Spacelab program has hosted a cross-disciplinary research agenda over a 17-year flight history. Several variations of Spacelab were used to host payloads for almost every space research discipline that NASA pursues-life sciences, microgravity research, space sciences, and earth observation studies. After seventeen years of flight, Spacelab modules, pallets, or variations thereof flew on the Shuttle 36 times for a total of 375 flight days.

Nonreciprocal Thermal Material by Spatiotemporal Modulation

NASA Astrophysics Data System (ADS)

Torrent, Daniel; Poncelet, Olivier; Batsale, Jean-Chirstophe

2018-03-01

The thermal properties of a material with a spatiotemporal modulation, in the form of a traveling wave, in both the thermal conductivity and the specific heat capacity are studied. It is found that these materials behave as materials with an internal convectionlike term that provides them with nonreciprocal properties, in the sense that the heat flux has different properties when it propagates in the same direction or in the opposite one to the modulation of the parameters. An effective medium description is presented which accurately describes the modulated material, and numerical simulations support this description and verify the nonreciprocal properties of the material. It is found that these materials are promising candidates for the design of thermal diodes and other advanced devices for the control of the heat flow at all scales.

Lightwave technology in microwave systems

NASA Astrophysics Data System (ADS)

Popa, A. E.; Gee, C. M.; Yen, H. W.

1986-01-01

Many advanced microwave system concepts such as active aperture phased array antennas use distributed topologies in which lightwave circuits are being proposed to interconnect both the analog and digital modules of the system. Lightwave components designed to implement these interconnects are reviewed and their performance analyzed. The impact of trends in component development are discussed.

A Methodology to Teach Advanced A/D Converters, Combining Digital Signal Processing and Microelectronics Perspectives

ERIC Educational Resources Information Center

Quintans, C.; Colmenar, A.; Castro, M.; Moure, M. J.; Mandado, E.

2010-01-01

ADCs (analog-to-digital converters), especially Pipeline and Sigma-Delta converters, are designed using complex architectures in order to increase their sampling rate and/or resolution. Consequently, the learning of ADC devices also encompasses complex concepts such as multistage synchronization, latency, oversampling, modulation, noise shaping,…

An Earth Orbiting Satellite Service and Repair Facility

NASA Technical Reports Server (NTRS)

Berndt, Andrew; Cardoza, Mike; Chen, John; Daley, Gunter; Frizzell, Andy; Linton, Richard; Rast, Wayne

1989-01-01

A conceptual design was produced for the Geosynchronous Satellite Servicing Platform (GSSP), an orbital facility capable of repairing and servicing satellites in geosynchronous orbit. The GSSP is a man-tended platform, which consists of a habitation module, operations module, service bay and truss assembly. This design review includes an analysis of life support systems, thermal and power requirements, robotic and automated systems, control methods and navigation, and communications systems. The GSSP will utilize existing technology available at the time of construction, focusing mainly on modifying and integrating existing systems. The entire facility, along with two satellite retrieval vehicles (SRV), will be placed in geosynchronous orbit by the Advanced Launch System. The SRV will be used to ferry satellites to and from the GSSP. Technicians will be transferred from Earth to the GSSP and back in an Apollo-derived Crew Transfer Capsule (CTC). These missions will use advanced telerobotic equipment to inspect and service satellites. Four of these missions are tentatively scheduled per year. At this rate, the GSSP will service over 650 satelites during the projected 25 year lifespan.

The SSM/PMAD automated test bed project

NASA Technical Reports Server (NTRS)

Lollar, Louis F.

1991-01-01

The Space Station Module/Power Management and Distribution (SSM/PMAD) autonomous subsystem project was initiated in 1984. The project's goal has been to design and develop an autonomous, user-supportive PMAD test bed simulating the SSF Hab/Lab module(s). An eighteen kilowatt SSM/PMAD test bed model with a high degree of automated operation has been developed. This advanced automation test bed contains three expert/knowledge based systems that interact with one another and with other more conventional software residing in up to eight distributed 386-based microcomputers to perform the necessary tasks of real-time and near real-time load scheduling, dynamic load prioritizing, and fault detection, isolation, and recovery (FDIR).

Spartan service module finite element modeling technique and analysis

NASA Technical Reports Server (NTRS)

Lindenmoyer, A. J.

1985-01-01

Sounding rockets have served as a relatively inexpensive and easy method of carrying experiments into the upper atmosphere. Limited observation time and pointing capabilities suggested the development of a new sounding rocket type carrier compatible with NASA's Space Transportation System. This concept evolved into the Spartan program, now credited with a successful Spartan 101 mission launched in June 1985. The next series of Spartans will use a service module primary structure. This newly designed reusable and universal component in the Spartan carrier system required thorough analysis and evaluation for flight certification. Using advanced finite element modeling techniques, the structure was analyzed and determined acceptable by meeting strict design goals and will be tested for verification of the analytical results.

The Structural Ceramics Database: Technical Foundations

PubMed Central

Munro, R. G.; Hwang, F. Y.; Hubbard, C. R.

1989-01-01

The development of a computerized database on advanced structural ceramics can play a critical role in fostering the widespread use of ceramics in industry and in advanced technologies. A computerized database may be the most effective means of accelerating technology development by enabling new materials to be incorporated into designs far more rapidly than would have been possible with traditional information transfer processes. Faster, more efficient access to critical data is the basis for creating this technological advantage. Further, a computerized database provides the means for a more consistent treatment of data, greater quality control and product reliability, and improved continuity of research and development programs. A preliminary system has been completed as phase one of an ongoing program to establish the Structural Ceramics Database system. The system is designed to be used on personal computers. Developed in a modular design, the preliminary system is focused on the thermal properties of monolithic ceramics. The initial modules consist of materials specification, thermal expansion, thermal conductivity, thermal diffusivity, specific heat, thermal shock resistance, and a bibliography of data references. Query and output programs also have been developed for use with these modules. The latter program elements, along with the database modules, will be subjected to several stages of testing and refinement in the second phase of this effort. The goal of the refinement process will be the establishment of this system as a user-friendly prototype. Three primary considerations provide the guidelines to the system’s development: (1) The user’s needs; (2) The nature of materials properties; and (3) The requirements of the programming language. The present report discusses the manner and rationale by which each of these considerations leads to specific features in the design of the system. PMID:28053397

Design and implementation of ATCA-based 100Gbps DP-QPSK optical signal test instrument

NASA Astrophysics Data System (ADS)

Su, Shaojing; Qin, Jiangyi; Huang, Zhiping; Liu, Chenwu

2014-11-01

In order to achieve the receiving task of 100Gbps Dual Polarization-Quadrature Phase Shift Keying (DP-QPSK) optical signal acquisition instrument, improve acquisition performance of the instrument, this paper has deeply researched DP-QPSK modulation principles, demodulation techniques and the key technologies of optical signal acquisition. The theories of DP-QPSK optical signal transmission are researched. The DP-QPSK optical signal transmission model is deduced. And the clock and data recovery in high-speed data acquisition and offset correction of multi-channel data are researched. By reasonable hardware circuit design and software system construction, the utilization of high performance Advanced Telecom Computing Architecture (ATCA), this paper proposes a 100Gbps DP-QPSK optical signal acquisition instrument which is based on ATCA. The implementations of key modules are presented by comparison and argumentation. According to the modularization idea, the instrument can be divided into eight modules. Each module performs the following functions. (1) DP-QPSK coherent detection demodulation module; (2) deceleration module; (3) FPGA (Field Programmable Gate Array); (4) storage module; (5) data transmission module; (6) clock module; (7) power module; (8) JTAG debugging, configuration module; What is more, this paper has put forward two solutions to test optical signal acquisition instrument performance. The first scenario is based on a standard STM-256 optical signal format and exploits the SignalTap of QuartusII software to monitor the optical signal data. Another scenario is to use a pseudo-random signal series to generate data, acquisition module acquires a certain amount of data signals, and then the signals are transferred to a computer by the Gigabit Ethernet to analyze. Two testing results show that the bit error rate of optical signal acquisition instrument is low. And the instrument fully meets the requirements of signal receiving system. At the same time this design has an important significance in practical applications.

Space architecture monograph series. Volume 4: Genesis 2: Advanced lunar outpost

NASA Technical Reports Server (NTRS)

Fieber, Joseph P.; Huebner-Moths, Janis; Paruleski, Kerry L.; Moore, Gary T. (Editor)

1991-01-01

This research and design study investigated advanced lunar habitats for astronauts and mission specialists on the Earth's moon. Design recommendations are based on environmental response to the lunar environment, human habitability (human factors and environmental behavior research), transportability (structural and materials system with least mass), constructability (minimizing extravehicular time), construction dependability and resilience, and suitability for NASA launch research missions in the 21st century. The recommended design uses lunar lava tubes, with construction being a combination of Space Station Freedom derived hard modules and light weight Kevlar laminate inflatable structures. The proposed habitat includes research labs and a biotron, crew quarters and crew support facility, mission control, health maintenance facility, maintenance work areas for psychological retreat, privacy, and comtemplation. Furniture, specialized equipment, and lighting are included in the analysis and design. Drawings include base master plans, construction sequencing, overall architectural configuration, detailed floor plans, sections and axonometrics, with interior perspectives.

Application Reuse Library for Software, Requirements, and Guidelines

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Thronesbery, Carroll

1994-01-01

Better designs are needed for expert systems and other operations automation software, for more reliable, usable and effective human support. A prototype computer-aided Application Reuse Library shows feasibility of supporting concurrent development and improvement of advanced software by users, analysts, software developers, and human-computer interaction experts. Such a library expedites development of quality software, by providing working, documented examples, which support understanding, modification and reuse of requirements as well as code. It explicitly documents and implicitly embodies design guidelines, standards and conventions. The Application Reuse Library provides application modules with Demo-and-Tester elements. Developers and users can evaluate applicability of a library module and test modifications, by running it interactively. Sub-modules provide application code and displays and controls. The library supports software modification and reuse, by providing alternative versions of application and display functionality. Information about human support and display requirements is provided, so that modifications will conform to guidelines. The library supports entry of new application modules from developers throughout an organization. Example library modules include a timer, some buttons and special fonts, and a real-time data interface program. The library prototype is implemented in the object-oriented G2 environment for developing real-time expert systems.

Coupling the System Analysis Module with SAS4A/SASSYS-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fanning, T. H.; Hu, R.

2016-09-30

SAS4A/SASSYS-1 is a simulation tool used to perform deterministic analysis of anticipated events as well as design basis and beyond design basis accidents for advanced reactors, with an emphasis on sodium fast reactors. SAS4A/SASSYS-1 has been under development and in active use for nearly forty-five years, and is currently maintained by the U.S. Department of Energy under the Office of Advanced Reactor Technology. Although SAS4A/SASSYS-1 contains a very capable primary and intermediate system modeling component, PRIMAR-4, it also has some shortcomings: outdated data management and code structure makes extension of the PRIMAR-4 module somewhat difficult. The user input format formore » PRIMAR-4 also limits the number of volumes and segments that can be used to describe a given system. The System Analysis Module (SAM) is a fairly new code development effort being carried out under the U.S. DOE Nuclear Energy Advanced Modeling and Simulation (NEAMS) program. SAM is being developed with advanced physical models, numerical methods, and software engineering practices; however, it is currently somewhat limited in the system components and phenomena that can be represented. For example, component models for electromagnetic pumps and multi-layer stratified volumes have not yet been developed. Nor is there support for a balance of plant model. Similarly, system-level phenomena such as control-rod driveline expansion and vessel elongation are not represented. This report documents fiscal year 2016 work that was carried out to couple the transient safety analysis capabilities of SAS4A/SASSYS-1 with the system modeling capabilities of SAM under the joint support of the ART and NEAMS programs. The coupling effort was successful and is demonstrated by evaluating an unprotected loss of flow transient for the Advanced Burner Test Reactor (ABTR) design. There are differences between the stand-alone SAS4A/SASSYS-1 simulations and the coupled SAS/SAM simulations, but these are mainly attributed to the limited maturity of the SAM development effort. The severe accident modeling capabilities in SAS4A/SASSYS-1 (sodium boiling, fuel melting and relocation) will continue to play a vital role for a long time. Therefore, the SAS4A/SASSYS-1 modernization effort should remain a high priority task under the ART program to ensure continued participation in domestic and international SFR safety collaborations and design optimizations. On the other hand, SAM provides an advanced system analysis tool, with improved numerical solution schemes, data management, code flexibility, and accuracy. SAM is still in early stages of development and will require continued support from NEAMS to fulfill its potential and to mature into a production tool for advanced reactor safety analysis. The effort to couple SAS4A/SASSYS-1 and SAM is the first step on the integration of these modeling capabilities.« less

COMPRES Mineral Physics Educational Modules for Advanced Undergraduates and Graduate Students

NASA Astrophysics Data System (ADS)

Burnley, P. C.; Thomas, S.

2012-12-01

The Consortium for Materials Properties Research in Earth Sciences (COMPRES) is a community-based consortium whose goal is to advance and facilitate experimental high pressure research in the Earth Sciences. An important aspect of this goal is sharing our knowledge with the next generation of researchers. To facilitate this, we have created a group of web-based educational modules on mineral physics topics. The modules reside in the On Cutting Edge, Teaching Mineralogy collection on the Science Education Resource Center (SERC) website. Although the modules are designed to function as part of a full semester course, each module can also stand alone. Potential users of the modules include mineral physics faculty teaching "bricks and mortar" classes at their own institutions, or in distance education setting, mineralogy teachers interested in including supplementary material in their mineralogy class, undergraduates doing independent study projects and graduate students and colleagues in other sub-disciplines who wish to brush up on a mineral physics topic. We used the modules to teach an on-line course entitled "Introduction to Mineral Physics" during the spring 2012 semester. More than 20 students and postdocs as well as 15 faculty and senior scientists participated in the course which met twice weekly as a webinar. Recordings of faculty lectures and student-led discussions of journal articles are now available upon request and edited versions of the lectures will be incorporated into the educational modules. Our experience in creating the modules and the course indicates that the use of 1) community-generated internet-based resources and 2) webinars to enable shared teaching between faculty at different universities, has the potential to both enrich graduate education and create efficiencies for university faculty.;

Research studies on advanced optical module/head designs for optical devices

NASA Technical Reports Server (NTRS)

Burke, James J.

1991-01-01

A summary is presented of research in optical data storage materials and of research at the center. The first section contains summary reports under the general headings of: (1) Magnetooptic media: modeling, design, fabrication, characterization, and testing; (2) Optical heads: holographic optical elements; and (3) Optical heads: integrated optics. The second section consist of a proposal entitled, Signal Processing Techniques for Optical Data Storage. And section three presents various publications prepared by the center.

Intensity-Modulated Advanced X-ray Source (IMAXS) for Homeland Security Applications

NASA Astrophysics Data System (ADS)

Langeveld, Willem G. J.; Johnson, William A.; Owen, Roger D.; Schonberg, Russell G.

2009-03-01

X-ray cargo inspection systems for the detection and verification of threats and contraband require high x-ray energy and high x-ray intensity to penetrate dense cargo. On the other hand, low intensity is desirable to minimize the radiation footprint. A collaboration between HESCO/PTSE Inc., Schonberg Research Corporation and Rapiscan Laboratories, Inc. has been formed in order to design and build an Intensity-Modulated Advanced X-ray Source (IMAXS). Such a source would allow cargo inspection systems to achieve up to two inches greater imaging penetration capability, while retaining the same average radiation footprint as present fixed-intensity sources. Alternatively, the same penetration capability can be obtained as with conventional sources with a reduction of the average radiation footprint by about a factor of three. The key idea is to change the intensity of the source for each x-ray pulse based on the signal strengths in the inspection system detector array during the previous pulse. In this paper we describe methods to accomplish pulse-to-pulse intensity modulation in both S-band (2998 MHz) and X-band (9303 MHz) linac sources, with diode or triode (gridded) electron guns. The feasibility of these methods has been demonstrated. Additionally, we describe a study of a shielding design that would allow a 6 MV X-band source to be used in mobile applications.

Development of ITM Oxygen Technology for Low-cost and Low-emission Gasification and Other Industrial Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fogash, Kevin

2015-12-15

Air Products carried out a scope of work under DOE Award No. DE-FE0012065 “Development of ITM Oxygen Technology for Low-cost and Low-emission Gasification and Other Industrial Applications” with subcontractors Ceramatec, Penn State, and WorleyParsons. The scope of work under this award was aimed at furthering the development of the Ion Transport Membrane (ITM) Oxygen production process toward a demonstration-scale facility known as the Oxygen Development Facility (ODF). Specific activities will help to enable design and construction of the ODF through advancement of a number of challenging technical elements that are required to manage risk in the initial deployment of ITMmore » technology. Major objectives of the work included developing ITM Oxygen ceramic membrane materials with improved performance and reliability, optimizing ceramic module geometry and fabrication methods, testing module performance, trialing the improved fabrication process at commercial scale in the Ceramic Membrane Module Fabrication Facility (CerFab), and advancing engineering development of the ITM oxygen production process, including vessel design and contaminant control measures to prepare for deployment of the ODF. The comprehensive report that follows details the team’s work, which includes several notable accomplishments: 1) compressive creep, a likely limiter of ceramic module lifetime in service, was demonstrated to be retarded by an order of magnitude by changes in material formulation, module joining dimensions, and internal wafer geometry; 2) two promising new materials were shown to be superior to the incumbent ITM material in a key material parameter related to oxygen flux; 3) module degradation mechanisms were identified following operation in large pilot-scale equipment; 4) options for utilizing ITM in a coal-to-liquids (CTL) facility to enable liquids production with carbon capture were identified and studied; and 5) the benefits of potential improvements to the technology were assessed for their cost impact on ITM Oxygen applications to clean power, fuels, and other applications.« less

Development of ITM Oxygen Technology for Low-cost and Low-emission Gasification and Other Industrial Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fogash, Kevin

Air Products carried out a scope of work under DOE Award No. DE-FE0012065 “Development of ITM Oxygen Technology for Low-cost and Low-emission Gasification and Other Industrial Applications” with subcontractors Ceramatec, Penn State, and WorleyParsons. The scope of work under this award was aimed at furthering the development of the Ion Transport Membrane (ITM) Oxygen production process toward a demonstration-scale facility known as the Oxygen Development Facility (ODF). Specific activities will help to enable design and construction of the ODF through advancement of a number of challenging technical elements that are required to manage risk in the initial deployment of ITMmore » technology. Major objectives of the work included developing ITM Oxygen ceramic membrane materials with improved performance and reliability, optimizing ceramic module geometry and fabrication methods, testing module performance, trialing the improved fabrication process at commercial scale in the Ceramic Membrane Module Fabrication Facility (CerFab), and advancing engineering development of the ITM oxygen production process, including vessel design and contaminant control measures to prepare for deployment of the ODF. The comprehensive report that follows details the team’s work, which includes several notable accomplishments: 1) compressive creep, a likely limiter of ceramic module lifetime in service, was demonstrated to be retarded by an order of magnitude by changes in material formulation, module joining dimensions, and internal wafer geometry; 2) two promising new materials were shown to be superior to the incumbent ITM material in a key material parameter related to oxygen flux; 3) module degradation mechanisms were identified following operation in large pilot-scale equipment; 4) options for utilizing ITM in a coal-to-liquids (CTL) facility to enable liquids production with carbon capture were identified and studied; and 5) the benefits of potential improvements to the technology were assessed for their cost impact on ITM Oxygen applications to clean power, fuels, and other applications.« less

Advanced Small Modular Reactor (SMR) Probabilistic Risk Assessment (PRA) Technical Exchange Meeting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Curtis

2013-09-01

During FY13, the INL developed an advanced SMR PRA framework which has been described in the report Small Modular Reactor (SMR) Probabilistic Risk Assessment (PRA) Detailed Technical Framework Specification, INL/EXT-13-28974 (April 2013). In this framework, the various areas are considered: Probabilistic models to provide information specific to advanced SMRs Representation of specific SMR design issues such as having co-located modules and passive safety features Use of modern open-source and readily available analysis methods Internal and external events resulting in impacts to safety All-hazards considerations Methods to support the identification of design vulnerabilities Mechanistic and probabilistic data needs to support modelingmore » and tools In order to describe this framework more fully and obtain feedback on the proposed approaches, the INL hosted a technical exchange meeting during August 2013. This report describes the outcomes of that meeting.« less

A small terminal for satellite communication systems

NASA Technical Reports Server (NTRS)

Xiong, Fuqin; Wu, Dong; Jin, Min

1994-01-01

A small portable, low-cost satellite communications terminal system incorporating a modulator/demodulator and convolutional-Viterbi coder/decoder is described. Advances in signal processing and error-correction techniques in combination with higher power and higher frequencies aboard satellites allow for more efficient use of the space segment. This makes it possible to design small economical earth stations. The Advanced Communications Technology Satellite (ACTS) was chosen to test the system. ACTS, operating at the Ka band incorporates higher power, higher frequency, frequency and spatial reuse using spot beams and polarization.

Dynamic array processing for computationally intensive expert systems in CLIPS

NASA Technical Reports Server (NTRS)

Athavale, N. N.; Ragade, R. K.; Fenske, T. E.; Cassaro, M. A.

1990-01-01

This paper puts forth an architecture for implementing a loop for advanced data structure of arrays in CLIPS. An attempt is made to use multi-field variables in such an architecture to process a set of data during the decision making cycle. Also, current limitations on the expert system shells are discussed in brief in this paper. The resulting architecture is designed to circumvent the current limitations set by the expert system shell and also by the operating environment. Such advanced data structures are needed for tightly coupling symbolic and numeric computation modules.

Analysis, design, and experimental results for lightweight space heat receiver canisters, phase 1

NASA Technical Reports Server (NTRS)

Schneider, Michael G.; Brege, Mark A.; Heidenreich, Gary R.

1991-01-01

Critical technology experiments have been performed on thermal energy storage modules in support of the Brayton Advanced Heat Receiver program. The modules are wedge-shaped canisters designed to minimize the mechanical stresses that occur during the phase change of the lithium fluoride phase change material. Nickel foam inserts were used in some of the canisters to provide thermal conductivity enhancement and to distribute the void volume. Two canisters, one with a nickel foam insert, and one without, were thermally cycled in various orientations in a fluidized bed furnace. The only measurable impact of the nickel foam was seen when the back and short sides of the canister were insulated to simulate operation in the advanced receiver design. In tests with insulation, the furnace to back side delta T was larger in the canister with the nickel foam insert, probably due to the radiant absorptivity of the nickel. However, the differences in the temperature profiles of the two canisters were small, and in many cases the profiles matched fairly well. Computed Tomography (CT) was successfully used to nondestructively demarcate void locations in the canisters. Finally, canister dimensional stability, which was measured throughout the thermal cycling test program with an inspection fixture was satisfactory with a maximum change of 0.635 mm (0.025 in.).

Integration of a Communicating Science Module into an Advanced Chemistry Laboratory Course

ERIC Educational Resources Information Center

Renaud, Jessica; Squier, Christopher; Larsen, Sarah C.

2006-01-01

A communicating science module was introduced into an advanced undergraduate physical chemistry laboratory course. The module was integrated into the course such that students received formal instruction in communicating science interwoven with the chemistry laboratory curriculum. The content of the communicating science module included three…

Infusional 5-FU for advanced colorectal cancer.

PubMed

Lokich, J

1995-01-01

5-Fluorouracil (5-FU) has been studied over the past two decades in five prospective randomized trials comparing bolus with infusional schedules. Response rates and time to progression are improved with infusional schedules and survival as determined by the proportion of patients alive at 2 years is also superior for infusional administration. Biochemical modulation of infusional 5-FU by leucovorin or interferon does not increase the therapeutic effect (in contrast to the modulation of bolus delivery) but does effect the toxicity profile adversely. Time modulation of infusional 5-FU has been reported to improve response rates, and survival over constant or flat infusion and additional studies are ongoing. A proposed experimental design for a comparative trial in advanced colon cancer is presented to address the questions of the optimal infusion duration; the role of dose intensity; and the role of chronomodulation. The application of infusional 5-FU into the adjuvant setting seems to be a reasonable step, and such trials have been initiated in both the United States and the United Kingdom. Bolus single agent 5-FU should be abandoned as a treatment option for colon cancer.

SMART: The Future of Spaceflight Avionics

NASA Technical Reports Server (NTRS)

Alhorn, Dean C.; Howard, David E.

2010-01-01

A novel avionics approach is necessary to meet the future needs of low cost space and lunar missions that require low mass and low power electronics. The current state of the art for avionics systems are centralized electronic units that perform the required spacecraft functions. These electronic units are usually custom-designed for each application and the approach compels avionics designers to have in-depth system knowledge before design can commence. The overall design, development, test and evaluation (DDT&E) cycle for this conventional approach requires long delivery times for space flight electronics and is very expensive. The Small Multi-purpose Advanced Reconfigurable Technology (SMART) concept is currently being developed to overcome the limitations of traditional avionics design. The SMART concept is based upon two multi-functional modules that can be reconfigured to drive and sense a variety of mechanical and electrical components. The SMART units are key to a distributed avionics architecture whereby the modules are located close to or right at the desired application point. The drive module, SMART-D, receives commands from the main computer and controls the spacecraft mechanisms and devices with localized feedback. The sensor module, SMART-S, is used to sense the environmental sensors and offload local limit checking from the main computer. There are numerous benefits that are realized by implementing the SMART system. Localized sensor signal conditioning electronics reduces signal loss and overall wiring mass. Localized drive electronics increase control bandwidth and minimize time lags for critical functions. These benefits in-turn reduce the main processor overhead functions. Since SMART units are standard flight qualified units, DDT&E is reduced and system design can commence much earlier in the design cycle. Increased production scale lowers individual piece part cost and using standard modules also reduces non-recurring costs. The benefit list continues, but the overall message is already evident: the SMART concept is an evolution in spacecraft avionics. SMART devices have the potential to change the design paradigm for future satellites, spacecraft and even commercial applications.

Protein Structure and Function: An Interdisciplinary Multimedia-Based Guided-Inquiry Education Module for the High School Science Classroom

ERIC Educational Resources Information Center

Bethel, Casey M.; Lieberman, Raquel L.

2014-01-01

Here we present a multidisciplinary educational unit intended for general, advanced placement, or international baccalaureate-level high school science, focused on the three-dimensional structure of proteins and their connection to function and disease. The lessons are designed within the framework of the Next Generation Science Standards to make…

In-situ calibration: migrating control system IP module calibration from the bench to the storage ring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, Jonah M.; Chin, Michael

2002-04-30

The Control System for the Advanced Light Source (ALS) at Lawrence Berkeley National Lab (LBNL) uses in-house designed IndustryPack(registered trademark) (IP) modules contained in compact PCI (cPCI) crates with 16-bit analog I/O to control instrumentation. To make the IP modules interchangeable, each module is calibrated for gain and offset compensation. We initially developed a method of verifying and calibrating the IP modules in a lab bench test environment using a PC with LabVIEW. The subsequent discovery that the ADCs have significant drift characteristics over periods of days of installed operation prompted development of an ''in-situ'' calibration process--one in which themore » IP modules can be calibrated without removing them from the cPCI crates in the storage ring. This paper discusses the original LabVIEW PC calibration and the migration to the proposed in-situ EPICS control system calibration.« less

Solid polymer electrolyte water electrolysis system development. [to generate oxygen for manned space station applications

NASA Technical Reports Server (NTRS)

1975-01-01

Solid polymer electrolyte technology used in a water electrolysis system (WES) to generate oxygen and hydrogen for manned space station applications was investigated. A four-man rated, low pressure breadboard water electrolysis system with the necessary instrumentation and controls was fabricated and tested. A six man rated, high pressure, high temperature, advanced preprototype WES was developed. This configuration included the design and development of an advanced water electrolysis module, capable of operation at 400 psig and 200 F, and a dynamic phase separator/pump in place of a passive phase separator design. Evaluation of this system demonstrated the goal of safe, unattended automated operation at high pressure and high temperature with an accumulated gas generation time of over 1000 hours.

Theoretical Design of a Depolarized Interferometric Fiber-Optic Gyroscope (IFOG) on SMF-28 Single-Mode Standard Optical Fiber Based on Closed-Loop Sinusoidal Phase Modulation with Serrodyne Feedback Phase Modulation Using Simulation Tools for Tactical and Industrial Grade Applications

PubMed Central

Pérez, Ramón José; Álvarez, Ignacio; Enguita, José María

2016-01-01

This article presents, by means of computational simulation tools, a full analysis and design of an Interferometric Fiber-Optic Gyroscope (IFOG) prototype based on a closed-loop configuration with sinusoidal bias phase- modulation. The complete design of the different blocks, optical and electronic, is presented, including some novelties as the sinusoidal bias phase-modulation and the use of an integrator to generate the serrodyne phase-modulation signal. The paper includes detailed calculation of most parameter values, and the plots of the resulting signals obtained from simulation tools. The design is focused in the use of a standard single-mode optical fiber, allowing a cost competitive implementation compared to commercial IFOG, at the expense of reduced sensitivity. The design contains an IFOG model that accomplishes tactical and industrial grade applications (sensitivity ≤ 0.055 °/h). This design presents two important properties: (1) an optical subsystem with advanced conception: depolarization of the optical wave by means of Lyot depolarizers, which allows to use a sensing coil made by standard optical fiber, instead by polarization maintaining fiber, which supposes consequent cost savings and (2) a novel and simple electronic design that incorporates a linear analog integrator with reset in feedback chain, this integrator generating a serrodyne voltage-wave to apply to Phase-Modulator (PM), so that it will be obtained the interferometric phase cancellation. This particular feedback design with sawtooth-wave generated signal for a closed-loop configuration with sinusoidal bias phase modulation has not been reported till now in the scientific literature and supposes a considerable simplification with regard to previous designs based on similar configurations. The sensing coil consists of an 8 cm average diameter spool that contains 300 m of standard single-mode optical-fiber (SMF-28 type) realized by quadrupolar winding. The working wavelength will be 1310 nm. The theoretical calculated values of threshold sensitivity and dynamic range for this prototype are 0.052 °/h and 101.38 dB (from ±1.164 × 10−5 °/s up to ±78.19 °/s), respectively. The Scale-Factor (SF) non-linearity for this model is 5.404% relative to full scale, this value being obtained from data simulation results. PMID:27128924

Theoretical Design of a Depolarized Interferometric Fiber-Optic Gyroscope (IFOG) on SMF-28 Single-Mode Standard Optical Fiber Based on Closed-Loop Sinusoidal Phase Modulation with Serrodyne Feedback Phase Modulation Using Simulation Tools for Tactical and Industrial Grade Applications.

PubMed

Pérez, Ramón José; Álvarez, Ignacio; Enguita, José María

2016-04-27

This article presents, by means of computational simulation tools, a full analysis and design of an Interferometric Fiber-Optic Gyroscope (IFOG) prototype based on a closed-loop configuration with sinusoidal bias phase- modulation. The complete design of the different blocks, optical and electronic, is presented, including some novelties as the sinusoidal bias phase-modulation and the use of an integrator to generate the serrodyne phase-modulation signal. The paper includes detailed calculation of most parameter values, and the plots of the resulting signals obtained from simulation tools. The design is focused in the use of a standard single-mode optical fiber, allowing a cost competitive implementation compared to commercial IFOG, at the expense of reduced sensitivity. The design contains an IFOG model that accomplishes tactical and industrial grade applications (sensitivity ≤ 0.055 °/h). This design presents two important properties: (1) an optical subsystem with advanced conception: depolarization of the optical wave by means of Lyot depolarizers, which allows to use a sensing coil made by standard optical fiber, instead by polarization maintaining fiber, which supposes consequent cost savings and (2) a novel and simple electronic design that incorporates a linear analog integrator with reset in feedback chain, this integrator generating a serrodyne voltage-wave to apply to Phase-Modulator (PM), so that it will be obtained the interferometric phase cancellation. This particular feedback design with sawtooth-wave generated signal for a closed-loop configuration with sinusoidal bias phase modulation has not been reported till now in the scientific literature and supposes a considerable simplification with regard to previous designs based on similar configurations. The sensing coil consists of an 8 cm average diameter spool that contains 300 m of standard single-mode optical-fiber (SMF-28 type) realized by quadrupolar winding. The working wavelength will be 1310 nm. The theoretical calculated values of threshold sensitivity and dynamic range for this prototype are 0.052 °/h and 101.38 dB (from ±1.164 × 10(-5) °/s up to ±78.19 °/s), respectively. The Scale-Factor (SF) non-linearity for this model is 5.404% relative to full scale, this value being obtained from data simulation results.

Advanced technologies for encryption of satellite links

NASA Astrophysics Data System (ADS)

McMahan, Sherry S.

The use of encryption on satellite links is discussed. Advanced technology exists to provide transmission security for large earth station with data rates up to 50 megabits per second. One of the major concerns in the use of encryption equipment with very small aperture terminals (VSAT) is the key management issue and the related operational costs. The low cost requirement and the lack of physical protection of remote VSATs place severe constraints on the design of encryption equipment. Encryption may be accomplished by embedding a tamper proof encryption module into the baseband unit of each VSAT. VSAT networks are usually star networks where there is a single large earth station that serves as a hub and all satellite communications takes place between each VSAT and the hub earth station. The hub earth station has the secret master key of each VSAT. These master keys are used to downline load encrypted session keys to each VSAT. A more secure alternative is to use public key techniques where each embedded VSAT encryption module internally generates its own secret and public numbers. The secret number never leaves the module while the public number is sent to the hub at the time of initialization of the encryption module into the VSAT. Physical access control to encryption modules of VSAT systems can be implemented using passwords, smart cards or biometrics.

Space Launch System Co-Manifested Payload Options for Habitation

NASA Technical Reports Server (NTRS)

Smitherman, David

2015-01-01

The Space Launch System (SLS) has a co-manifested payload capability that will grow over time as the rocket matures and planned upgrades are implemented. The final configuration is planned to be capable of inserting a payload greater than 10 metric tons (mt) into a trans-lunar injection trajectory along with the crew in the Orion capsule and the service module. The co-manifested payload is located below the Orion and its service module in a 10-meter high fairing similar to the way the Saturn launch vehicle carried the lunar lander below the Apollo command and service modules. A variety of approaches have been explored that utilizes this co-manifested payload capability to build up infrastructure in deep space in support of future asteroid, lunar, and Mars mission scenarios. This paper is a report on the findings from the Advanced Concepts Office study team at the NASA Marshall Space Flight Center, working with the Advanced Exploration Systems Program on the Exploration Augmentation Module Project. It includes some of the possible options for habitation in the co-manifested payload volume on SLS. Findings include module designs that can be developed in 10mt increments to support these missions, including overall conceptual layouts, mass properties, and approaches for integration into various scenarios for near-term support of deep space habitat research and technology development, support to asteroid exploration, and long range support for Mars transfer flights.

Deep Space Habitat Configurations Based On International Space Station Systems

NASA Technical Reports Server (NTRS)

Smitherman, David; Russell, Tiffany; Baysinger, Mike; Capizzo, Pete; Fabisinski, Leo; Griffin, Brand; Hornsby, Linda; Maples,Dauphne; Miernik, Janie

2012-01-01

A Deep Space Habitat (DSH) is the crew habitation module designed for long duration missions. Although humans have lived in space for many years, there has never been a habitat beyond low-Earth-orbit. As part of the Advanced Exploration Systems (AES) Habitation Project, a study was conducted to develop weightless habitat configurations using systems based on International Space Station (ISS) designs. Two mission sizes are described for a 4-crew 60-day mission, and a 4-crew 500-day mission using standard Node, Lab, and Multi-Purpose Logistics Module (MPLM) sized elements, and ISS derived habitation systems. These durations were selected to explore the lower and upper bound for the exploration missions under consideration including a range of excursions within the Earth-Moon vicinity, near earth asteroids, and Mars orbit. Current methods for sizing the mass and volume for habitats are based on mathematical models that assume the construction of a new single volume habitat. In contrast to that approach, this study explored the use of ISS designs based on existing hardware where available and construction of new hardware based on ISS designs where appropriate. Findings included a very robust design that could be reused if the DSH were assembled and based at the ISS and a transportation system were provided for its return after each mission. Mass estimates were found to be higher than mathematical models due primarily to the use of multiple ISS modules instead of one new large module, but the maturity of the designs using flight qualified systems have potential for improved cost, schedule, and risk benefits.

Deep Space Habitat Configurations Based on International Space Station Systems

NASA Technical Reports Server (NTRS)

Smitherman, David; Russell, Tiffany; Baysinger, Mike; Capizzo, Pete; Fabisinski, Leo; Griffin, Brand; Hornsby, Linda; Maples, Dauphne; Miernik, Janie

2012-01-01

A Deep Space Habitat (DSH) is the crew habitation module designed for long duration missions. Although humans have lived in space for many years, there has never been a habitat beyond low-Earth-orbit. As part of the Advanced Exploration Systems (AES) Habitation Project, a study was conducted to develop weightless habitat configurations using systems based on International Space Station (ISS) designs. Two mission sizes are described for a 4-crew 60-day mission, and a 4-crew 500-day mission using standard Node, Lab, and Multi-Purpose Logistics Module (MPLM) sized elements, and ISS derived habitation systems. These durations were selected to explore the lower and upper bound for the exploration missions under consideration including a range of excursions within the Earth-Moon vicinity, near earth asteroids, and Mars orbit. Current methods for sizing the mass and volume for habitats are based on mathematical models that assume the construction of a new single volume habitat. In contrast to that approach, this study explored the use of ISS designs based on existing hardware where available and construction of new hardware based on ISS designs where appropriate. Findings included a very robust design that could be reused if the DSH were assembled and based at the ISS and a transportation system were provided for its return after each mission. Mass estimates were found to be higher than mathematical models due primarily to the use of multiple ISS modules instead of one new large module, but the maturity of the designs using flight qualified systems have potential for improved cost, schedule, and risk benefits.

Optical design of automotive headlight system incorporating digital micromirror device.

PubMed

Hung, Chuan-Cheng; Fang, Yi-Chin; Huang, Ming-Shyan; Hsueh, Bo-Ren; Wang, Shuan-Fu; Wu, Bo-Wen; Lai, Wei-Chi; Chen, Yi-Liang

2010-08-01

In recent years, the popular adaptive front-lighting automobile headlight system has become a main emphasis of research that manufacturers will continue to focus great efforts on in the future. In this research we propose a new integral optical design for an automotive headlight system with an advanced light-emitting diode and digital micromirror device (DMD). Traditionally, automobile headlights have all been designed as a low beam light module, whereas the high beam light module still requires using accessory lamps. In anticipation of this new concept of integral optical design, we have researched and designed a single optical system with high and low beam capabilities. To switch on and off the beams, a DMD is typically used. Because DMDs have the capability of redirecting incident light into a specific angle, they also determine the shape of the high or low light beam in order to match the standard of headlight illumination. With collocation of the multicurvature reflection lens design, a DMD can control the light energy distribution and thereby reinforce the resolution of the light beam.

Rolling dry-coupled transducers for ultrasonic inspections of aging aircraft structures

NASA Astrophysics Data System (ADS)

Komsky, Igor N.

2004-07-01

Some advanced aircraft materials or coatings are porous or otherwise sensitive to the application of water, gel, or some other ultrasonic couplants. To overcome the problems associated with the liquid coupling medium, dry-coupled rolling modules were developed at Northwestern University for the transmission of both longitudinal and transverse ultrasonic waves at frequencies up to 10 MHz. Dry-coupled ultrasonic modules contain solid core internal stators and solid or flexible external rotors with the flexible polymer substrates. Two types of the dry-coupled modules are under development. Cylindrical base transducer modules include solid core cylindrical rotors with flexible polymer substrates that rotate around the stators with ultrasonic elements. Dry-coupled modules with elongated bases contain solid core stators and flexible track-like polymer substrates that rotate around the stators as rotors of the modules. The elongated base modules have larger contact interfaces with the inspection surface in comparison with the cylindrical base modules. Some designs of the dry-coupled rolling modules contain several ultrasonic elements with different incident angles or a variable angle unit for rapid adjustments of incident angles. The prototype dry-coupled rolling modules were integrated with the portable ultrasonic inspection systems and tested on a number of Boeing aircraft structures.

A programmable controller based on CAN field bus embedded microprocessor and FPGA

NASA Astrophysics Data System (ADS)

Cai, Qizhong; Guo, Yifeng; Chen, Wenhei; Wang, Mingtao

2008-10-01

One kind of new programmable controller(PLC) is introduced in this paper. The advanced embedded microprocessor and Field-Programmable Gate Array (FPGA) device are applied in the PLC system. The PLC system structure was presented in this paper. It includes 32 bits Advanced RISC Machines (ARM) embedded microprocessor as control core, FPGA as control arithmetic coprocessor and CAN bus as data communication criteria protocol connected the host controller and its various extension modules. It is detailed given that the circuits and working principle, IiO interface circuit between ARM and FPGA and interface circuit between ARM and FPGA coprocessor. Furthermore the interface circuit diagrams between various modules are written. In addition, it is introduced that ladder chart program how to control the transfer info of control arithmetic part in FPGA coprocessor. The PLC, through nearly two months of operation to meet the design of the basic requirements.

Evaluation of advanced cooling therapy's esophageal cooling device for core temperature control.

PubMed

Naiman, Melissa; Shanley, Patrick; Garrett, Frank; Kulstad, Erik

2016-05-01

Managing core temperature is critical to patient outcomes in a wide range of clinical scenarios. Previous devices designed to perform temperature management required a trade-off between invasiveness and temperature modulation efficiency. The Esophageal Cooling Device, made by Advanced Cooling Therapy (Chicago, IL), was developed to optimize warming and cooling efficiency through an easy and low risk procedure that leverages heat transfer through convection and conduction. Clinical data from cardiac arrest, fever, and critical burn patients indicate that the Esophageal Cooling Device performs very well both in terms of temperature modulation (cooling rates of approximately 1.3°C/hour, warming of up to 0.5°C/hour) and maintaining temperature stability (variation around goal temperature ± 0.3°C). Physicians have reported that device performance is comparable to the performance of intravascular temperature management techniques and superior to the performance of surface devices, while avoiding the downsides associated with both.

SiC Multi-Chip Power Modules as Power-System Building Blocks

NASA Technical Reports Server (NTRS)

Lostetter, Alexander; Franks, Steven

2007-01-01

The term "SiC MCPMs" (wherein "MCPM" signifies "multi-chip power module") denotes electronic power-supply modules containing multiple silicon carbide power devices and silicon-on-insulator (SOI) control integrated-circuit chips. SiC MCPMs are being developed as building blocks of advanced expandable, reconfigurable, fault-tolerant power-supply systems. Exploiting the ability of SiC semiconductor devices to operate at temperatures, breakdown voltages, and current densities significantly greater than those of conventional Si devices, the designs of SiC MCPMs and of systems comprising multiple SiC MCPMs are expected to afford a greater degree of miniaturization through stacking of modules with reduced requirements for heat sinking. Moreover, the higher-temperature capabilities of SiC MCPMs could enable operation in environments hotter than Si-based power systems can withstand. The stacked SiC MCPMs in a given system can be electrically connected in series, parallel, or a series/parallel combination to increase the overall power-handling capability of the system. In addition to power connections, the modules have communication connections. The SOI controllers in the modules communicate with each other as nodes of a decentralized control network, in which no single controller exerts overall command of the system. Control functions effected via the network include synchronization of switching of power devices and rapid reconfiguration of power connections to enable the power system to continue to supply power to a load in the event of failure of one of the modules. In addition to serving as building blocks of reliable power-supply systems, SiC MCPMs could be augmented with external control circuitry to make them perform additional power-handling functions as needed for specific applications: typical functions could include regulating voltages, storing energy, and driving motors. Because identical SiC MCPM building blocks could be utilized in a variety of ways, the cost and difficulty of designing new, highly reliable power systems would be reduced considerably. Several prototype DC-to-DC power-converter modules containing SiC power-switching devices were designed and built to demonstrate the feasibility of the SiC MCPM concept. In anticipation of a future need for operation at high temperature, the circuitry in the modules includes high-temperature inductors and capacitors. These modules were designed to be stacked to construct a system of four modules electrically connected in series and/or parallel. The packaging of the modules is designed to satisfy requirements for series and parallel interconnection among modules, high power density, high thermal efficiency, small size, and light weight. Each module includes four output power connectors two for serial and two for parallel output power connections among the modules. Each module also includes two signal connectors, electrically isolated from the power connectors, that afford four zones for signal interconnections among the SOI controllers. Finally, each module includes two input power connectors, through which it receives power from an in-line power bus. This design feature is included in anticipation of a custom-designed power bus incorporating sockets compatible with snap-on type connectors to enable rapid replacement of failed modules.

Reconfigurable, Cognitive Software-Defined Radio

NASA Technical Reports Server (NTRS)

Bhat, Arvind

2015-01-01

Software-defined radio (SDR) technology allows radios to be reconfigured to perform different communication functions without using multiple radios to accomplish each task. Intelligent Automation, Inc., has developed SDR platforms that switch adaptively between different operation modes. The innovation works by modifying both transmit waveforms and receiver signal processing tasks. In Phase I of the project, the company developed SDR cognitive capabilities, including adaptive modulation and coding (AMC), automatic modulation recognition (AMR), and spectrum sensing. In Phase II, these capabilities were integrated into SDR platforms. The reconfigurable transceiver design employs high-speed field-programmable gate arrays, enabling multimode operation and scalable architecture. Designs are based on commercial off-the-shelf (COTS) components and are modular in nature, making it easier to upgrade individual components rather than redesigning the entire SDR platform as technology advances.

Advances in radiation oncology for the management of oropharyngeal tumors.

PubMed

Gunn, G Brandon; Frank, Steven J

2013-08-01

The major benefits of modern radiation therapy (eg, intensity-modulated [x-ray] radiation therapy [IMRT]) for oropharyngeal cancer are reduced xerostomia and better quality of life. Intensity-modulated proton therapy may provide additional advantages over IMRT by reducing radiation beam-path toxicities. Several acute and late treatment-related toxicities and symptom constellations must be kept in mind when designing and comparing future treatment strategies, particularly because currently most patients with oropharyngeal carcinoma present with human papillomavirus-positive disease and are expected to have a high probability of long-term survival after treatment. Copyright © 2013 Elsevier Inc. All rights reserved.

Project T.E.A.M. (Technical Education Advancement Modules). Fundementals of Workplace Integration.

ERIC Educational Resources Information Center

Kraeling, Vicki

This module is one of a series of instructional guides developed by Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training for unemployed, underemployed, and existing industrial employees whose basic technical skills are in need of upgrading. The module is a 27-hour overview course…

Evolutionary growth for Space Station Freedom electrical power system

NASA Technical Reports Server (NTRS)

Marshall, Matthew Fisk; Mclallin, Kerry; Zernic, Mike

1989-01-01

Over an operational lifetime of at least 30 yr, Space Station Freedom will encounter increased Space Station user requirements and advancing technologies. The Space Station electrical power system is designed with the flexibility to accommodate these emerging technologies and expert systems and is being designed with the necessary software hooks and hardware scars to accommodate increased growth demand. The electrical power system is planned to grow from the initial 75 kW up to 300 kW. The Phase 1 station will utilize photovoltaic arrays to produce the electrical power; however, for growth to 300 kW, solar dynamic power modules will be utilized. Pairs of 25 kW solar dynamic power modules will be added to the station to reach the power growth level. The addition of solar dynamic power in the growth phase places constraints in the initial Space Station systems such as guidance, navigation, and control, external thermal, truss structural stiffness, computational capabilities and storage, which must be planned-in, in order to facilitate the addition of the solar dynamic modules.

Advanced astigmatism-corrected Czerny-Turner imaging spectrometer in spectral broadband

NASA Astrophysics Data System (ADS)

Cong, Hai-fang

2014-12-01

This paper reports an advanced Czerny-Turner optical structure which is used for the application in imaging spectrometers. To obtain the excellent imaging quality, a cylindrical lens with a wedge angle is used between the focusing mirror and the imaging plane to remove astigmatism in broadband. It makes the advanced optical system presents high resolution over the full bandwidth and decreases the cost. An example of the imaging spectrometer in the waveband of 260nm~520nm has been designed to prove our theory. It yields the excellent modulation transfer functions (MTF) of all fields of view which are more than 0.75 over the broadband under the required Nyquist frequency (20lp/mm).

Advanced nickel-hydrogen cell configuration study

NASA Technical Reports Server (NTRS)

Adler, E.; Perez, F.

1984-01-01

Three nickel hydrogen battery designs, individual pressure vessel (IPV), common pressure vessel (CPV), and a bipolar battery module were studied. Weight, system complexity and cost were compared for a satellite operating in a 6 hour, 5600 nautical mile orbit. The required energy storage is 52 kWh. A 25% improvement in specific energy is observed by employing a bipolar battery versus a battery comprised of hundreds of IPV's. Further weight benefits are realized by the development of light weight technologies in the bipolar design.

The Direct FuelCell™ stack engineering

NASA Astrophysics Data System (ADS)

Doyon, J.; Farooque, M.; Maru, H.

FuelCell Energy (FCE) has developed power plants in the size range of 300 kW to 3 MW for distributed power generation. Field-testing of the sub-megawatt plants is underway. The FCE power plants are based on its Direct FuelCell™ (DFC) technology. This is so named because of its ability to generate electricity directly from a hydrocarbon fuel, such as natural gas, by reforming it inside the fuel cell stack itself. All FCE products use identical 8000 cm 2 cell design, approximately 350-400 cells per stack, external gas manifolds, and similar stack compression systems. The difference lies in the packaging of the stacks inside the stack module. The sub-megawatt system stack module contains a single horizontal stack whereas the MW-class stack module houses four identical vertical stacks. The commonality of the design, internal reforming features, and atmospheric operation simplify the system design, reduce cost, improve efficiency, increase reliability and maintainability. The product building-block stack design has been advanced through three full-size stack operations at company's headquarters in Danbury, CT. The initial proof-of-concept of the full-size stack design was verified in 1999, followed by a 1.5 year of endurance verification in 2000-2001, and currently a value-engineered stack version is in operation. This paper discusses the design features, important engineering solutions implemented, and test results of FCE's full-size DFC stacks.

A Soft-Switching Inverter for High-Temperature Advanced Hybrid Electric Vehicle Traction Motor Drives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lai, Jason; Yu, Wensong; Sun, Pengwei

2012-03-31

The state-of-the-art hybrid electric vehicles (HEVs) require the inverter cooling system to have a separate loop to avoid power semiconductor junction over temperatures because the engine coolant temperature of 105°C does not allow for much temperature rise in silicon devices. The proposed work is to develop an advanced soft-switching inverter that will eliminate the device switching loss and cut down the power loss so that the inverter can operate at high-temperature conditions while operating at high switching frequencies with small current ripple in low inductance based permanent magnet motors. The proposed tasks also include high-temperature packaging and thermal modeling andmore » simulation to ensure the packaged module can operate at the desired temperature. The developed module will be integrated with the motor and vehicle controller for dynamometer and in-vehicle testing to prove its superiority. This report will describe the detailed technical design of the soft-switching inverters and their test results. The experiments were conducted both in module level for the module conduction and switching characteristics and in inverter level for its efficiency under inductive and dynamometer load conditions. The performance will be compared with the DOE original specification.« less

Advanced thermionic energy conversion

NASA Technical Reports Server (NTRS)

1979-01-01

Developments towards space and terrestrial applications of thermionic energy conversion are presented. Significant accomplishments for the three month period include: (1) devised a blade-type distributed lead design with many advantages compared to the stud-type distributed lead; (2) completed design of Marchuk tube test apparatus; (3) concluded, based on current understanding, that residual hydrogen should not contribute to a negative space charge barrier at the collector; (4) modified THX design program to include series-coupled designs as well as inductively-coupled designs; (5) initiated work on the heat transfer technology, THX test module, output power transfer system, heat transfer system, and conceptual plant design tasks; and (6) reached 2200 hours of operation in JPL-5 cylindrical converter envelope test.

On the Fracture Toughness and Crack Growth Resistance of Bio-Inspired Thermal Spray Hybrid Composites

NASA Astrophysics Data System (ADS)

Resnick, Michael Murray

Surface exploration of the Moon and Asteroids can provide important information to scientists regarding the origins of the solar-system and life . Small robots and sensor modules can enable low-cost surface exploration. In the near future, they are the main machines providing these answers. Advanced in electronics, sensors and actuators enable ever smaller platforms, with compromising functionality. However similar advances haven't taken place for power supplies and thermal control system. The lunar south pole has temperatures in the range of -100 to -150 °C. Similarly, asteroid surfaces can encounter temperatures of -150 °C. Most electronics and batteries do not work below -40 °C. An effective thermal control system is critical towards making small robots and sensors module for extreme environments feasible. In this work, the feasibility of using thermochemical storage materials as a possible thermal control solution is analyzed for small robots and sensor modules for lunar and asteroid surface environments. The presented technology will focus on using resources that is readily generated as waste product aboard a spacecraft or is available off-world through In-Situ Resource Utilization (ISRU). In this work, a sensor module for extreme environment has been designed and prototyped. Our intention is to have a network of tens or hundreds of sensor modules that can communicate and interact with each other while also gathering science data. The design contains environmental sensors like temperature sensors and IMU (containing accelerometer, gyro and magnetometer) to gather data. The sensor module would nominally contain an electrical heater and insulation. The thermal heating effect provided by this active heater is compared with the proposed technology that utilizes thermochemical storage chemicals. Our results show that a thermochemical storage-based thermal control system is feasible for use in extreme temperatures. A performance increase of 80% is predicted for the sensor modules on the asteroid Eros using thermochemical based storage system. At laboratory level, a performance increase of 8 to 9 % is observed at ambient temperatures of -32°C and -40 °C.

PAM4 silicon photonic microring resonator-based transceiver circuits

NASA Astrophysics Data System (ADS)

Palermo, Samuel; Yu, Kunzhi; Roshan-Zamir, Ashkan; Wang, Binhao; Li, Cheng; Seyedi, M. Ashkan; Fiorentino, Marco; Beausoleil, Raymond

2017-02-01

Increased data rates have motivated the investigation of advanced modulation schemes, such as four-level pulseamplitude modulation (PAM4), in optical interconnect systems in order to enable longer transmission distances and operation with reduced circuit bandwidth relative to non-return-to-zero (NRZ) modulation. Employing this modulation scheme in interconnect architectures based on high-Q silicon photonic microring resonator devices, which occupy small area and allow for inherent wavelength-division multiplexing (WDM), offers a promising solution to address the dramatic increase in datacenter and high-performance computing system I/O bandwidth demands. Two ring modulator device structures are proposed for PAM4 modulation, including a single phase shifter segment device driven with a multi-level PAM4 transmitter and a two-segment device driven by two simple NRZ (MSB/LSB) transmitters. Transmitter circuits which utilize segmented pulsed-cascode high swing output stages are presented for both device structures. Output stage segmentation is utilized in the single-segment device design for PAM4 voltage level control, while in the two-segment design it is used for both independent MSB/LSB voltage levels and impedance control for output eye skew compensation. The 65nm CMOS transmitters supply a 4.4Vppd output swing for 40Gb/s operation when driving depletion-mode microring modulators implemented in a 130nm SOI process, with the single- and two-segment designs achieving 3.04 and 4.38mW/Gb/s, respectively. A PAM4 optical receiver front-end is also described which employs a large input-stage feedback resistor transimpedance amplifier (TIA) cascaded with an adaptively-tuned continuous-time linear equalizer (CTLE) for improved sensitivity. Receiver linearity, critical in PAM4 systems, is achieved with a peak-detector-based automatic gain control (AGC) loop.

Special Features of the Advanced Loans Module of the ABCD Integrated Library System

ERIC Educational Resources Information Center

de Smet, Egbert

2011-01-01

Purpose: The "advanced loans" module of the relatively new library software, ABCD, is an addition to the normal loans module and it offers a "generic transaction decision-making engine" functionality. The module requires extra installation effort and parameterisation, so this article aims to explain to the many potentially interested libraries,…

The Use of Uas for Rapid 3d Mapping in Geomatics Education

NASA Astrophysics Data System (ADS)

Teo, Tee-Ann; Tian-Yuan Shih, Peter; Yu, Sz-Cheng; Tsai, Fuan

2016-06-01

With the development of technology, UAS is an advance technology to support rapid mapping for disaster response. The aim of this study is to develop educational modules for UAS data processing in rapid 3D mapping. The designed modules for this study are focused on UAV data processing from available freeware or trial software for education purpose. The key modules include orientation modelling, 3D point clouds generation, image georeferencing and visualization. The orientation modelling modules adopts VisualSFM to determine the projection matrix for each image station. Besides, the approximate ground control points are measured from OpenStreetMap for absolute orientation. The second module uses SURE and the orientation files from previous module for 3D point clouds generation. Then, the ground point selection and digital terrain model generation can be archived by LAStools. The third module stitches individual rectified images into a mosaic image using Microsoft ICE (Image Composite Editor). The last module visualizes and measures the generated dense point clouds in CloudCompare. These comprehensive UAS processing modules allow the students to gain the skills to process and deliver UAS photogrammetric products in rapid 3D mapping. Moreover, they can also apply the photogrammetric products for analysis in practice.

Electromechanical actuation for thrust vector control applications

NASA Technical Reports Server (NTRS)

Roth, Mary Ellen

1990-01-01

The advanced launch system (ALS), is a launch vehicle that is designed to be cost-effective, highly reliable, and operationally efficient with a goal of reducing the cost per pound to orbit. An electromechanical actuation (EMA) system is being developed as an attractive alternative to the hydraulic systems. The controller will integrate 20 kHz resonant link power management and distribution (PMAD) technology and pulse population modulation (PPM) techniques to implement field-oriented vector control (FOVC) of a new advanced induction motor. The driver and the FOVC will be microprocessor controlled. For increased system reliability, a built-in test (BITE) capability will be included. This involves introducing testability into the design of a system such that testing is calibrated and exercised during the design, manufacturing, maintenance, and prelaunch activities. An actuator will be integrated with the motor controller for performance testing of the EMA thrust vector control (TVC) system. The EMA system and work proposed for the future are discussed.

Tomorrow is Today: A Plan for Implementing the Study of the Future in the English Classroom.

ERIC Educational Resources Information Center

Thompson, David

This course, designed to help students explore serious thoughts about the future of society, is intended for an English literature class at the advanced secondary level. The course consists of nine interrelated modules that deal with the following topics: current predictions about the future, with special attention to the film "Future Shock";…

Evaluating a Teaching Module on Ethically Responsible Evidence-Based Practice Decision Making in an Advanced Micro Practice Course

ERIC Educational Resources Information Center

Wong, Rose

2017-01-01

This article adds to the growing body of literature on the use of evidence-based practice (EBP) in social work. Specifically, it examines a 9-hour EBP educational model designed to prepare MSW students for appropriate decision-making strategies in working with multicultural client populations. The model places emphasis on identification and…

Second Helping: An Advanced Enrichment Course for Family Child Care Providers. Program Information Package. [Revised.

ERIC Educational Resources Information Center

Windflower Enterprises, Colorado Springs, CO.

Second Helping is a 32-hour, 4-module course designed by and for family child care providers to address issues of concern to the provider, such as individual well-being, business skills, family relations, and child development. This booklet discusses the Second Helping family child care provider training course and outlines the qualifications…

A spin-modulated telescope for measurement of cosmic microwave background anisotropy

NASA Astrophysics Data System (ADS)

Staren, John William

The measurement of anisotropy in the Cosmic Microwave Background (CMB) advances our knowledge of the early Universe from which the radiation originated. The angular power spectrum of CMB anisotropy at sub-degree scales depends heavily on comsological parameters such as Ob, O 0 and H0. In pursuit of critical power spectrum measurements over a range of angular scales, a spin-modulated telescope with a single cryogenic amplifier used in a total power radiometer is designed, built and tested. The new technique of spin-modulation with a spinning flat mirror canted 2.5° relative to its spin axis modulates the beam in a 10° oval pattern on the sky at 2.5 Hz. This rapid two-dimensional modulation of the beam is tested at balloon altitudes to minimize the atmospheric offset and determine the efficacy of the scan and telescope design. Maps of over 600 and 400 square degrees are made of regions observed using the spin-modulation and a 20° azimuth scan. These maps yield a 95% confidence level flat band power upper limit of DeltaTℓ = Tcmb(ℓ(ℓ + 1)Cℓ/2pi)0.5 < 77 muK at ℓ = 38 and are free of systematics effects and striping due to long-term drifts in our amplifier to the levels tested here. Planning for the next telescope, with multiple amplifiers, is performed to ensure its success.

The application of virtual prototyping methods to determine the dynamic parameters of mobile robot

NASA Astrophysics Data System (ADS)

Kurc, Krzysztof; Szybicki, Dariusz; Burghardt, Andrzej; Muszyńska, Magdalena

2016-04-01

The paper presents methods used to determine the parameters necessary to build a mathematical model of an underwater robot with a crawler drive. The parameters present in the dynamics equation will be determined by means of advanced mechatronic design tools, including: CAD/CAE software andMES modules. The virtual prototyping process is described as well as the various possible uses (design adaptability) depending on the optional accessories added to the vehicle. A mathematical model is presented to show the kinematics and dynamics of the underwater crawler robot, essential for the design stage.

Biochemical modulation of 5-fluorouracil by methotrexate in patients with advanced gastric carcinoma.

PubMed

Pérez, J E; Lacava, J A; Dominguez, M E; Rodriguez, R; Barbieri, M R; Ortiz, E H; Romero Acuña, L A; Langhi, M J; Romero Acuña, J M; Vallejo, C T; Leone, B A; Machiavelli, M R; Romero, A O

1998-10-01

A phase II trial was conducted to evaluate the efficacy and toxicity of a modulation of 5-fluorouracil (5-FU) by methotrexate (MTX) (with leucovorin (LV) rescue) as first-line chemotherapy in patients with locally advanced (inoperable) or metastatic gastric carcinoma. From July 1993 through August 1996, 36 patients with advanced gastric carcinoma received a regimen that consisted of: MTX 200 mg/m2 diluted in 250 ml normal saline by intravenous infusion over 20 minutes at hour 0; 5-FU 1,200 mg/m2 intravenous push injection at hour 20. Beginning 24 hours after MTX administration all patients received LV 15 mg/m2 intramuscularly every 6 hours for six doses. Cycles were repeated every 15 days. One patient was not assessable for response. Objective regression was observed in 15 of 37 patients (43%; 95% confidence interval, 26%-60%). One patient (3%) achieved complete response and 14 (40%) achieved partial response. No change was recorded in 14 patients (40%) and progressive disease was noted in six patients (17%). The median time to treatment failure was 7 months and the median survival was 12 months. Toxicity was within acceptable limits but one therapy-related death resulting from severe leukopenia occurred. The dose-limiting toxicity was mucositis. Five episodes of grade 3 or 4 stomatitis were observed and caused dosage modifications of MTX and 5-FU. Biochemical modulation of 5-FU by MTX appears as an attractive modality in patients with advanced gastric cancer. Further investigation both in experimental and clinical fields is needed to clearly define its role and to design the best modulatory strategy.

A Leadership Intervention to Further the Training of Female Faculty (LIFT-OFF) in Radiology.

PubMed

Spalluto, Lucy B; Spottswood, Stephanie E; Deitte, Lori A; Chern, Alexander; Dewey, Charlene M

2017-06-01

Women are under-represented in the field of radiology, occupy a minority of leadership positions, and, at our institution, have not achieved the same level of academic success as their male counterparts. Consequently, the authors designed, implemented, and evaluated the Leadership Intervention to Further the Training of Female Faculty (LIFT-OFF) program to (1) improve access to opportunities for women's faculty development and advancement, and (2) improve clarification of expectations about the role and path of advancement. LIFT-OFF was developed based on the results of a needs assessment survey. The results generated 14 priority topics, which served as the basis for educational modules conducted by expert speakers. Module effectiveness was assessed with pre- and postsurveys to elicit participant knowledge about the targeted subject matter. A formative program evaluation was performed at the completion of year 1 of 2 to assess outcomes and impacts to date. Seventeen of 55 (31%) educational module post-survey questions demonstrated a statistically significant (P < 0.05) increase in "yes" responses, indicating an improved understanding of targeted information. At year 1, 75% of the participants indicated that the program improved access to faculty development opportunities and 62% reported improved access to career advancement opportunities. Satisfaction with pace of professional advancement increased from 25% to 46% for junior women faculty (P = 0.046). Faculty development programs such as LIFT-OFF can provide career development opportunities and executive skills necessary for women to achieve academic career success and assume leadership positions. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

NASA. Lewis Research Center Advanced Modulation and Coding Project: Introduction and overview

NASA Technical Reports Server (NTRS)

Budinger, James M.

1992-01-01

The Advanced Modulation and Coding Project at LeRC is sponsored by the Office of Space Science and Applications, Communications Division, Code EC, at NASA Headquarters and conducted by the Digital Systems Technology Branch of the Space Electronics Division. Advanced Modulation and Coding is one of three focused technology development projects within the branch's overall Processing and Switching Program. The program consists of industry contracts for developing proof-of-concept (POC) and demonstration model hardware, university grants for analyzing advanced techniques, and in-house integration and testing of performance verification and systems evaluation. The Advanced Modulation and Coding Project is broken into five elements: (1) bandwidth- and power-efficient modems; (2) high-speed codecs; (3) digital modems; (4) multichannel demodulators; and (5) very high-data-rate modems. At least one contract and one grant were awarded for each element.

Method to implement the CCD timing generator based on FPGA

NASA Astrophysics Data System (ADS)

Li, Binhua; Song, Qian; He, Chun; Jin, Jianhui; He, Lin

2010-07-01

With the advance of the PFPA technology, the design methodology of digital systems is changing. In recent years we develop a method to implement the CCD timing generator based on FPGA and VHDL. This paper presents the principles and implementation skills of the method. Taking a developed camera as an example, we introduce the structure, input and output clocks/signals of a timing generator implemented in the camera. The generator is composed of a top module and a bottom module. The bottom one is made up of 4 sub-modules which correspond to 4 different operation modes. The modules are implemented by 5 VHDL programs. Frame charts of the architecture of these programs are shown in the paper. We also describe implementation steps of the timing generator in Quartus II, and the interconnections between the generator and a Nios soft core processor which is the controller of this generator. Some test results are presented in the end.

A teaching module about stellar structure and evolution

NASA Astrophysics Data System (ADS)

Colantonio, Arturo; Galano, Silvia; Leccia, Silvio; Puddu, Emanuella; Testa, Italo

2017-01-01

In this paper, we present a teaching module about stellar structure, functioning and evolution. Drawing from literature in astronomy education, we designed the activities around three key ideas: spectral analysis, mechanical and thermal equilibrium, energy and nuclear reactions. The module is divided into four phases, in which the key ideas for describing stars' functioning and physical mechanisms are gradually introduced. The activities (20 hours) build on previously learned laws in mechanics, thermodynamics, and electromagnetism and help students combine them meaningfully in order to get a complete picture of processes that happens in stars. The module was piloted with two intact classes of secondary school students (N = 59 students, 17-18 years old), using a ten-question multiple-choice questionnaire as research instrument. Results support the effectiveness of the proposed activities. Implications for the teaching of advanced physics topics using stars as fruitful context are briefly discussed.

Revolutionary Concepts for Helicopter Noise Reduction: SILENT Program

NASA Technical Reports Server (NTRS)

Edwards, Bryan; Cox, Charles; Booth, Earl R., Jr. (Technical Monitor)

2002-01-01

As part of a NASA initiative to reduce helicopter main rotor noise, a Phase 1 study has been performed of candidate noise reduction concepts. Both conventional and novel design technologies have been analyzed that reduce the community impact of helicopter operations. In this study the noise reduction potential and design implications are assessed for conventional means of noise reduction, e.g., tip speed reduction, tip shapes and airfoil tailoring, and for two innovative design concepts: modulated blade spacing and x-force control. Main rotor designs that incorporate modulated blade spacing are shown to have reduced peak noise levels in most flight operations. X-force control alters the helicopter's force balance whereby the miss distance between main rotor blades and shed vortices can be controlled. This control provides a high potential to mitigate BVI noise radiation. Each concept is evaluated using best practice design and analysis methods, achieving the study's aim to significantly reduce noise with minimal performance degradation and no vibration increase. It is concluded that a SILENT main rotor design, incorporating the modulated blade spacing concept, offers significantly reduced noise levels and the potential of a breakthrough in how a helicopter's sound is perceived and judged. The SILENT rotor represents a definite advancement in the state-of-the-art and is selected as the design concept for demonstration in Phase 2. A Phase 2 Implementation Plan is developed for whirl cage and wind tunnel evaluations of a scaled model SILENT rotor.

An advanced communications synthesizer

NASA Astrophysics Data System (ADS)

Scherer, Ernst F.

1994-02-01

With the proliferation of smaller and lower cost EHF terminals, the fast-hopping microwave synthesizer subsystem is rapidly becoming the limiting factor for further size and cost reduction. A new approach, based on a high-speed direct digital synthesizer (DDS) and a very fast voltage controlled oscillator (VCO) tracking loop, has yielded a highly integrable design with true low-cost potential. A frequency range of 1 to 20 GHz can be covered by a simple substitution of the VCO module. This advanced synthesizer realization promises a generic solution to a large class of synthesizer requirements, greatly facilitating standardization and promoting modular system concepts.

Advanced flight computer. Special study

NASA Technical Reports Server (NTRS)

Coo, Dennis

1995-01-01

This report documents a special study to define a 32-bit radiation hardened, SEU tolerant flight computer architecture, and to investigate current or near-term technologies and development efforts that contribute to the Advanced Flight Computer (AFC) design and development. An AFC processing node architecture is defined. Each node may consist of a multi-chip processor as needed. The modular, building block approach uses VLSI technology and packaging methods that demonstrate a feasible AFC module in 1998 that meets that AFC goals. The defined architecture and approach demonstrate a clear low-risk, low-cost path to the 1998 production goal, with intermediate prototypes in 1996.

Intelligent Engine Systems: Thermal Management and Advanced Cooling

NASA Technical Reports Server (NTRS)

Bergholz, Robert

2008-01-01

The objective of the Advanced Turbine Cooling and Thermal Management program is to develop intelligent control and distribution methods for turbine cooling, while achieving a reduction in total cooling flow and assuring acceptable turbine component safety and reliability. The program also will develop embedded sensor technologies and cooling system models for real-time engine diagnostics and health management. Both active and passive control strategies will be investigated that include the capability of intelligent modulation of flow quantities, pressures, and temperatures both within the supply system and at the turbine component level. Thermal management system concepts were studied, with a goal of reducing HPT blade cooling air supply temperature. An assessment will be made of the use of this air by the active clearance control system as well. Turbine component cooling designs incorporating advanced, high-effectiveness cooling features, will be evaluated. Turbine cooling flow control concepts will be studied at the cooling system level and the component level. Specific cooling features or sub-elements of an advanced HPT blade cooling design will be downselected for core fabrication and casting demonstrations.

Apparel Manufacture

NASA Technical Reports Server (NTRS)

1995-01-01

Marshall Space Flight Center teamed with the University of Alabama in Huntsville (UAH) in 1989 on a program involving development of advanced simulation software. Concurrently, the State of Alabama chartered UAH to conduct a technology advancement program in support of the state's apparel manufacturers. In 1992, under contract to Marshall, UAH developed an apparel-specific software package that allows manufacturers to design and analyze modules without making an actual investment -- it functions on ordinary PC equipment. By 1995, Marshall had responded to requests for the package from more than 400 companies in 36 states; some of which reported savings up to $2 million. The National Garment Company of Missouri, for example, uses the system to design and balance a modular line before committing to expensive hardware; for setting up sewing lines; and for determining the composition of a new team.

High-performance packaging for monolithic microwave and millimeter-wave integrated circuits

NASA Technical Reports Server (NTRS)

Shalkhauser, K. A.; Li, K.; Shih, Y. C.

1992-01-01

Packaging schemes were developed that provide low-loss, hermetic enclosure for advanced monolithic microwave and millimeter-wave integrated circuits (MMICs). The package designs are based on a fused quartz substrate material that offers improved radio frequency (RF) performance through 44 gigahertz (GHz). The small size and weight of the packages make them appropriate for a variety of applications, including phased array antenna systems. Packages were designed in two forms; one for housing a single MMIC chip, the second in the form of a multi-chip phased array module. The single chip array module was developed in three separate sizes, for chips of different geometry and frequency requirements. The phased array module was developed to address packaging directly for antenna applications, and includes transmission line and interconnect structures to support multi-element operation. All packages are fabricated using fused quartz substrate materials. As part of the packaging effort, a test fixture was developed to interface the single chip packages to conventional laboratory instrumentation for characterization of the packaged devices. The package and test fixture designs were both developed in a generic sense, optimizing performance for a wide range of possible applications and devices.

A compact dual-band RF front-end and board design for vehicular platforms

NASA Astrophysics Data System (ADS)

Sharawi, Mohammad S.; Aloi, Daniel N.

2012-03-01

Modern vehicular platforms include several wireless systems that provide navigation, entertainment and road side assistance, among other services. These systems operate at different frequency bands and thus careful system-level design should be followed to minimise the interference between them. In this study, we present a compact dual-band RF front-end module for global positioning system (GPS) operating in the L1-band (1574.42-1576.42 MHz) and satellite digital audio radio system (SDARS) operating in the S-band (2320-2345 MHz). The module provides more than 26 dB of measured gain in both bands and low noise figure values of 0.9 and 1.2 dB in SDARS and GPS bands, respectively. The front-end has interference suppression capability from the advanced mobile phone system and personal communication service cellular bands. The module is designed on a low-cost FR-4 substrate material and occupies a small size of 62 × 29 × 1.3 mm3. It dissipates 235 mW in the SDARS section and 100 mW in the GPS section. Three prototypes have been built to verify a repeatable performance.

Person-centred communication: design, implementation and evaluation of a communication skills module or undergraduate nursing students - an Irish context.

PubMed

McCarthy, Bridie; O'Donovan, Moira; Twomey, Angela

2008-02-01

Despite wide agreement about the importance of effective communication in nursing there is continuing evidence of the need for nurses to improve their communication skills. Consequently, there is a growing demand for more therapeutic and person-centred communication courses. Studies on communication education reveal considerable variability on the design and operationalisation of these programmes. Additionally, the literature highlights that nurse educators are continually challenged with developing and implementing these programmes. Communication skills are generally taught in years one and two of undergraduate nursing degree programmes. This is a stage when students have minimal contact with patients and clients. We suggest that a communication skills module should be included in all final years of undergraduate nursing programmes. With an array of clinical experiences to draw from, final year nursing students are better placed to apply the skills of effective communication in practice. In this paper, we present the design, implementation and evaluation of an advanced communication skills module undertaken by fourth year undergraduate nursing students completing a Bachelor of Science (BSc) degree - nursing programme at one university in the Republic of Ireland.

A triple-mode hexa-standard reconfigurable TI cross-coupled ΣΔ modulator

NASA Astrophysics Data System (ADS)

Prakash A. V, Jos; Jose, Babita R.; Mathew, Jimson; Jose, Bijoy A.

2017-07-01

Hardware reconfigurability is an attractive solution for modern multi-standard wireless systems. This paper analyses the performance and implementation of an efficient triple-mode hexa-standard reconfigurable sigma-delta (∑Δ) modulator designed for six different wireless communication standards. Enhanced noise-shaping characteristics and increased digitisation rate, obtained by time-interleaved cross-coupling of ∑Δ paths, have been utilised for the modulator design. Power/hardware efficiency and the capability to acclimate the requirements of wide hexa-standard specifications are achieved by introducing an advanced noise-shaping structure, the dual-extended architecture. Simulation results of the proposed architecture using Hspice shows that the proposed modulator obtains a peak signal-to-noise ratio of 83.4/80.2/67.8/61.5/60.8/51.03 dB for hexa-standards, i.e. GSM/Bluetooth/GPS/WCDMA/WLAN/WiMAX standards with significantly less hardware and low operating frequency. The proposed architecture is implemented in 45 nm CMOS process using a 1 V supply and 0.7 V input range with a power consumption of 1.93 mW. Both architectural- and transistor-level simulation results prove the effectiveness and feasibility of this architecture to accomplish multi-standard cellular communication characteristics.

Study of flutter related computational procedures for minimum weight structural sizing of advanced aircraft

NASA Technical Reports Server (NTRS)

Oconnell, R. F.; Hassig, H. J.; Radovcich, N. A.

1976-01-01

Results of a study of the development of flutter modules applicable to automated structural design of advanced aircraft configurations, such as a supersonic transport, are presented. Automated structural design is restricted to automated sizing of the elements of a given structural model. It includes a flutter optimization procedure; i.e., a procedure for arriving at a structure with minimum mass for satisfying flutter constraints. Methods of solving the flutter equation and computing the generalized aerodynamic force coefficients in the repetitive analysis environment of a flutter optimization procedure are studied, and recommended approaches are presented. Five approaches to flutter optimization are explained in detail and compared. An approach to flutter optimization incorporating some of the methods discussed is presented. Problems related to flutter optimization in a realistic design environment are discussed and an integrated approach to the entire flutter task is presented. Recommendations for further investigations are made. Results of numerical evaluations, applying the five methods of flutter optimization to the same design task, are presented.

Advancing clinical development pathways for new CFTR modulators in cystic fibrosis.

PubMed

Mayer-Hamblett, Nicole; Boyle, Michael; VanDevanter, Donald

2016-05-01

Cystic fibrosis (CF) is a life-shortening genetic disease affecting approximately 70,000 individuals worldwide. Until recently, drug development efforts have emphasised therapies treating downstream signs and symptoms resulting from the underlying CF biological defect: reduced function of the CF transmembrane conductance regulator (CFTR) protein. The current CF drug development landscape has expanded to include therapies that enhance CFTR function by either restoring wild-type CFTR protein expression or increasing (modulating) the function of mutant CFTR proteins in cells. To date, two systemic small-molecule CFTR modulators have been evaluated in pivotal clinical trials in individuals with CF and specific mutant CFTR genotypes that have led to regulatory review and/or approval. Advances in the discovery of CFTR modulators as a promising new class of therapies have been impressive, yet work remains to develop highly effective, disease-modifying modulators for individuals of all CF genotypes. The objectives of this review are to outline the challenges and opportunities in drug development created by systemic genotype-specific CFTR modulators, highlight the advantages of sweat chloride as an established biomarker of CFTR activity to streamline early-phase development and summarise options for later phase clinical trial designs that respond to the adoption of approved genotype-specific modulators into standard of care. An optimal development framework will be needed to move the most promising therapies efficiently through the drug development pipeline and ultimately deliver efficacious and safe therapies to all individuals with CF. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Photovoltaic materials and devices 2016

DOE PAGES

Sopori, Bhushan; Basnyat, Prakash; Mehta, Vishal

2016-01-01

Photovoltaic energy continues to grow with about 59 GW of solar PV installed in 2015. While most of the PV production (about 93%) was Si wafer based, both CdTe and CI(G)S are growing in their shares. There is also continued progress at the laboratory scale in OPV and dye sensitized solar cells. As the market grows, emphasis on reducing the cost of modules and systems continues to grow. This is the fourth special issue of this journal that is dedicated to gathering selected papers on recent advances in materials, devices, and modules/PV systems. This issue contains sixteen papers on variousmore » aspects of photovoltaics. As a result, these fall in four broad categories of novel materials, device design and fabrication, modules, and systems.« less

Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newmarker, Marc; Campbell, Mark

2012-03-16

Design, validate at prototype level, and then demonstrate a full size, 800 MWht Thermal Energy Storage (TES) system based on Phase Changing Material (PCM) TES modules with round trip efficiency in excess of 93%. The PCM TES module would be the building block of a TES system which can be deployed at costs inline with the DOE benchmark of 2020. The development of a reliable, unsophisticated, modular, and scalable TES system designed to be massmanufactured utilizing advanced automated fabrication and assembly processes and field installed in the most cost-effective configuration could facilitate the attainment of a Levelized Cost of Energymore » (LCOE) of $.07/kWh by 2015. It was believed that the DOE targets can be attained by finding the best combinationTES module size, its optimal integration in the power cycle, and readily available PCM. Work under this project ultimately focused on the development and performance evaluation of a 100kWht prototype heat exchanger. The design utilizes a commercially available heat exchanger product to create a unique latent heat PCM storage module. The novel ideal associated with this technology is the inclusion of an agitation mechanism that is activated during the discharge process to improve heat transfer. The prototype unit did not meet the performance goals estimated through modeling, nor did the estimated costs of the system fall in line with the goals established by DOE.« less

Pulse power 350 V nickel-metal hydride battery power-D-005-00181

NASA Astrophysics Data System (ADS)

Eskra, Michael D.; Ralston, Paula; Salkind, Alvin; Plivelich, Robert F.

Energy-storage devices are needed for applications requiring very high-power over short periods of time. Such devices have various military (rail guns, electromagnetic launchers, and DEW) and commercial applications, such as hybrid electric vehicles, vehicle starting (SLI), and utility peak shaving. The storage and delivery of high levels of burst power can be achieved with a capacitor, flywheel, or rechargeable battery. In order to reduce the weight and volume of many systems they must contain advanced state-of-the-art electrochemical or electromechanical power sources. There is an opportunity and a need to develop energy-storage devices that have improved high-power characteristics compared to existing ultra capacitors, flywheels or rechargeable batteries. Electro Energy, Inc. has been engaged in the development of bipolar nickel-metal hydride batteries, which may fulfil the requirements of some of these applications. This paper describes a module rated at 300 V (255 cells) (6 Ah). The volume of the module is 23 L and the mass is 56 kg. The module is designed to deliver 50 kW pulses of 10 s duration at 50% state-of-charge. Details of the mechanical design of the module, safety considerations, along with the results of initial electrical characterization testing by the customer will be discussed. Some discussion of the possibilities for design optimization is also included.

GLOBECOM '88 - IEEE Global Telecommunications Conference and Exhibition, Hollywood, FL, Nov. 28-Dec. 1, 1988, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Various papers on communications for the information age are presented. Among the general topics considered are: telematic services and terminals, satellite communications, telecommunications mangaement network, control of integrated broadband networks, advances in digital radio systems, the intelligent network, broadband networks and services deployment, future switch architectures, performance analysis of computer networks, advances in spread spectrum, optical high-speed LANs, and broadband switching and networks. Also addressed are: multiple access protocols, video coding techniques, modulation and coding, photonic switching, SONET terminals and applications, standards for video coding, digital switching, progress in MANs, mobile and portable radio, software design for improved maintainability, multipath propagation and advanced countermeasure, data communication, network control and management, fiber in the loop, network algorithm and protocols, and advances in computer communications.

Selected OAST/OSSA space experiment activities in support of Space Station Freedom

NASA Astrophysics Data System (ADS)

Delombard, Richard

The Space Experiments Division at NASA Lewis Research Center is developing technology and science space experiments for the Office of Aeronautics and Space Technology (OAST) and the Office of Space Sciences and Applications (OSSA). Selected precursor experiments and technology development activities supporting the Space Station Freedom (SSF) are presented. The Tank Pressure Control Experiment (TPCE) is an OAST-funded cryogenic fluid dynamics experiment, the objective of which is to determine the effectiveness of jet mixing as a means of equilibrating fluid temperatures and controlling tank pressures, thereby permitting the design of lighter cryogenic tanks. The information from experiments such as this will be utilized in the design and operation of on board cryogenic storage for programs such as SSF. The Thermal Energy Storage Flight Project (TES) is an OAST-funded thermal management experiment involving phase change materials for thermal energy storage. The objective of this project is to develop and fly in-space experiments to characterize void shape and location in phase change materials used in a thermal energy storage configuration representative of an advanced solar dynamic system design. The information from experiments such as this will be utilized in the design of future solar dynamic power systems. The Solar Array Module Plasma Interaction Experiment (SAMPIE) is an OAST-funded experiment to determine the environmental effects of the low earth orbit (LEO) space plasma environment on state-of-the-art solar cell modules biased to high potentials relative to the plasma. Future spacecraft designs and structures will push the operating limits of solar cell arrays and other high voltage systems. SAMPIE will provide key information necessary for optimum module design and construction. The Vibration Isolation Technology (VIT) Advanced Technology Development effort is funded by OSSA to provide technology necessary to maintain a stable microgravity environment for sensitive payloads on board spacecraft. The proof of concept will be demonstrated by laboratory tests and in low-gravity aircraft flights. VIT is expected to be utilized by many SSF microgravity science payloads. The Space Acceleration Measurement System (SAMS) is an OSSA-funded instrument to measure the microgravity acceleration environment for OSSA payloads on the shuttle and SSF.

Selected OAST/OSSA space experiment activities in support of Space Station Freedom

NASA Technical Reports Server (NTRS)

Delombard, Richard

1992-01-01

The Space Experiments Division at NASA Lewis Research Center is developing technology and science space experiments for the Office of Aeronautics and Space Technology (OAST) and the Office of Space Sciences and Applications (OSSA). Selected precursor experiments and technology development activities supporting the Space Station Freedom (SSF) are presented. The Tank Pressure Control Experiment (TPCE) is an OAST-funded cryogenic fluid dynamics experiment, the objective of which is to determine the effectiveness of jet mixing as a means of equilibrating fluid temperatures and controlling tank pressures, thereby permitting the design of lighter cryogenic tanks. The information from experiments such as this will be utilized in the design and operation of on board cryogenic storage for programs such as SSF. The Thermal Energy Storage Flight Project (TES) is an OAST-funded thermal management experiment involving phase change materials for thermal energy storage. The objective of this project is to develop and fly in-space experiments to characterize void shape and location in phase change materials used in a thermal energy storage configuration representative of an advanced solar dynamic system design. The information from experiments such as this will be utilized in the design of future solar dynamic power systems. The Solar Array Module Plasma Interaction Experiment (SAMPIE) is an OAST-funded experiment to determine the environmental effects of the low earth orbit (LEO) space plasma environment on state-of-the-art solar cell modules biased to high potentials relative to the plasma. Future spacecraft designs and structures will push the operating limits of solar cell arrays and other high voltage systems. SAMPIE will provide key information necessary for optimum module design and construction. The Vibration Isolation Technology (VIT) Advanced Technology Development effort is funded by OSSA to provide technology necessary to maintain a stable microgravity environment for sensitive payloads on board spacecraft. The proof of concept will be demonstrated by laboratory tests and in low-gravity aircraft flights. VIT is expected to be utilized by many SSF microgravity science payloads. The Space Acceleration Measurement System (SAMS) is an OSSA-funded instrument to measure the microgravity acceleration environment for OSSA payloads on the shuttle and SSF.

Maintenance on the Advanced Colloids Experiment Module

NASA Image and Video Library

2018-04-16

iss055e035366 (April 16, 2018) --- NASA astronaut Ricky Arnold performs maintenance on the Advanced Colloids Experiment Module located inside the Light Microscopy Module which is a modified commercial, highly flexible, state-of-the-art light imaging microscope facility that provides researchers with powerful diagnostic hardware and software in microgravity.

Advancement of Bi-Level Integrated System Synthesis (BLISS)

NASA Technical Reports Server (NTRS)

Sobieszczanski-Sobieski, Jaroslaw; Emiley, Mark S.; Agte, Jeremy S.; Sandusky, Robert R., Jr.

2000-01-01

Bi-Level Integrated System Synthesis (BLISS) is a method for optimization of an engineering system, e.g., an aerospace vehicle. BLISS consists of optimizations at the subsystem (module) and system levels to divide the overall large optimization task into sets of smaller ones that can be executed concurrently. In the initial version of BLISS that was introduced and documented in previous publications, analysis in the modules was kept at the early conceptual design level. This paper reports on the next step in the BLISS development in which the fidelity of the aerodynamic drag and structural stress and displacement analyses were upgraded while the method's satisfactory convergence rate was retained.

Imidazoles and benzimidazoles as tubulin-modulators for anti-cancer therapy.

PubMed

Torres, Fernando C; García-Rubiño, M Eugenia; Lozano-López, César; Kawano, Daniel F; Eifler-Lima, Vera L; von Poser, Gilsane L; Campos, Joaquín M

2015-01-01

Imidazoles and benzimidazoles are privileged heterocyclic bioactive compounds used with success in the clinical practice of innumerous diseases. Although there are many advancements in cancer therapy, microtubules remain as one of the few macromolecular targets validated for planning active anti-cancer compounds, and the design of drugs that modulate microtubule dynamics in unknown sites of tubulin is one of the goals of the medicinal chemistry. The discussion of the role of new and commercially available imidazole and benzimidazole derivatives as tubulin modulators is scattered throughout scientific literature, and indicates that these compounds have a tubulin modulation mechanism different from that of tubulin modulators clinically available, such as paclitaxel, docetaxel, vincristine and vinblastine. In fact, recent literature indicates that these derivatives inhibit microtubule formation binding to the colchicine site, present good pharmacokinetic properties and are capable of overcoming multidrug resistance in many cell lines. The understanding of the mechanisms involved in the imidazoles/benzimidazoles modulation of microtubule dynamics is very important to develop new strategies to overcome the resistance to anti-cancer drugs and to discover new biomarkers and targets for cancer chemotherapy.

Development of a Power Electronics Controller for the Advanced Stirling Radioisotope Generator

NASA Technical Reports Server (NTRS)

Leland, Douglas K.; Priest, Joel F.; Keiter, Douglas E.; Schreiber, Jeffrey G.

2008-01-01

Under a U.S. Department of Energy program for radioisotope power systems, Lockheed Martin is developing an Engineering Unit of the Advanced Stirling Radioisotope Generator (ASRG). This is an advanced version of the previously reported SRG110 generator. The ASRG uses Advanced Stirling Convertors (ASCs) developed by Sunpower Incorporated under a NASA Research Announcement contract. The ASRG makes use of a Stirling controller based on power electronics that eliminates the tuning capacitors. The power electronics controller synchronizes dual-opposed convertors and maintains a fixed frequency operating point. The controller is single-fault tolerant and uses high-frequency pulse width modulation to create the sinusoidal currents that are nearly in phase with the piston velocity, eliminating the need for large series tuning capacitors. Sunpower supports this effort through an extension of their controller development intended for other applications. Glenn Research Center (GRC) supports this effort through system dynamic modeling, analysis and test support. The ASRG design arrived at a new baseline based on a system-level trade study and extensive feedback from mission planners on the necessity of single-fault tolerance. This paper presents the baseline design with an emphasis on the power electronics controller detailed design concept that will meet space mission requirements including single fault tolerance.

Validation Database Based Thermal Analysis of an Advanced RPS Concept

NASA Technical Reports Server (NTRS)

Balint, Tibor S.; Emis, Nickolas D.

2006-01-01

Advanced RPS concepts can be conceived, designed and assessed using high-end computational analysis tools. These predictions may provide an initial insight into the potential performance of these models, but verification and validation are necessary and required steps to gain confidence in the numerical analysis results. This paper discusses the findings from a numerical validation exercise for a small advanced RPS concept, based on a thermal analysis methodology developed at JPL and on a validation database obtained from experiments performed at Oregon State University. Both the numerical and experimental configurations utilized a single GPHS module enabled design, resembling a Mod-RTG concept. The analysis focused on operating and environmental conditions during the storage phase only. This validation exercise helped to refine key thermal analysis and modeling parameters, such as heat transfer coefficients, and conductivity and radiation heat transfer values. Improved understanding of the Mod-RTG concept through validation of the thermal model allows for future improvements to this power system concept.

Advanced Modeling of Micromirror Devices

NASA Technical Reports Server (NTRS)

Michalicek, M. Adrian; Sene, Darren E.; Bright, Victor M.

1995-01-01

The flexure-beam micromirror device (FBMD) is a phase only piston style spatial light modulator demonstrating properties which can be used for phase adaptive corrective optics. This paper presents a complete study of a square FBMD, from advanced model development through final device testing and model verification. The model relates the electrical and mechanical properties of the device by equating the electrostatic force of a parallel-plate capacitor with the counter-acting spring force of the device's support flexures. The capacitor solution is derived via the Schwartz-Christoffel transformation such that the final solution accounts for non-ideal electric fields. The complete model describes the behavior of any piston-style device, given its design geometry and material properties. It includes operational parameters such as drive frequency and temperature, as well as fringing effects, mirror surface deformations, and cross-talk from neighboring devices. The steps taken to develop this model can be applied to other micromirrors, such as the cantilever and torsion-beam designs, to produce an advanced model for any given device. The micromirror devices studied in this paper were commercially fabricated in a surface micromachining process. A microscope-based laser interferometer is used to test the device in which a beam reflected from the device modulates a fixed reference beam. The mirror displacement is determined from the relative phase which generates a continuous set of data for each selected position on the mirror surface. Plots of this data describe the localized deflection as a function of drive voltage.

Advanced Pediatric Brain Imaging Research and Training Program

DTIC Science & Technology

2015-10-01

post assessment scores (combined pretest AVG =64.5% to combined post - test AVG=94.04%). The scores demonstrate that online...techniques. This field test (s) included a (pre/ post : pre- test vs. post - test ) mixed design , with training being a between-subjects factor. We randomly... Post Test 98.0% The next section focuses on discussing the post -module survey results in which participants documented their

NASA wiring for space applications program test results

NASA Astrophysics Data System (ADS)

Stavnes, Mark; Hammoud, Ahmad

1995-11-01

The electrical power wiring tests results from the NASA Wiring for Space Applications program are presented. The goal of the program was to develop a base for the building of a lightweight, arc track-resistant electrical wiring system for aerospace applications. This new wiring system would be applied to such structures as pressurized modules, trans-atmospheric vehicles, LEO/GEO environments, and lunar and Martian environments. Technological developments from this program include the fabrication of new insulating materials, the production of new wiring constructions, an improved system design, and an advanced circuit protection design.

Solar concentrator advanced development project

NASA Technical Reports Server (NTRS)

Corrigan, Robert D.; Ehresman, Derik T.

1987-01-01

A solar dynamic concentrator design developed for use with a solar-thermodynamic power generation module intended for the Space Station is considered. The truss hexagonal panel reflector uses a modular design approach and is flexible in attainable flux profiles and assembly techniques. Preliminary structural, thermal, and optical analysis results are discussed. Accuracy of the surface reflectors should be within 5 mrad rms slope error, resulting in the need for close fabrication tolerances. Significant fabrication issues to be addressed include the facet reflective and protective coating processes and the surface specularity requirements.

An automation of design and modelling tasks in NX Siemens environment with original software - cost module

NASA Astrophysics Data System (ADS)

Zbiciak, R.; Grabowik, C.; Janik, W.

2015-11-01

The design-constructional process is a creation activity which strives to fulfil, as well as it possible at the certain moment of time, all demands and needs formulated by a user taking into account social, technical and technological advances. Engineer knowledge and skills and their inborn abilities have the greatest influence on the final product quality and cost. They have also deciding influence on product technical and economic value. Taking into account above it seems to be advisable to make software tools that support an engineer in the process of manufacturing cost estimation. The Cost module is built with analytical procedures which are used for relative manufacturing cost estimation. As in the case of the Generator module the Cost module was written in object programming language C# in Visual Studio environment. During the research the following eight factors, that have the greatest influence on overall manufacturing cost, were distinguished and defined: (i) a gear wheel teeth type it is straight or helicoidal, (ii) a gear wheel design shape A, B with or without wheel hub, (iii) a gear tooth module, (iv) teeth number, (v) gear rim width, (vi) gear wheel material, (vii) heat treatment or thermochemical treatment, (viii) accuracy class. Knowledge of parameters (i) to (v) is indispensable for proper modelling of 3D gear wheels models in CAD system environment. These parameters are also processed in the Cost module. The last three parameters it is (vi) to (viii) are exclusively used in the Cost module. The estimation of manufacturing relative cost is based on indexes calculated for each particular parameter. Estimated in this way the manufacturing relative cost gives an overview of design parameters influence on the final gear wheel manufacturing cost. This relative manufacturing cost takes values from 0.00 to 1,00 range. The bigger index value the higher relative manufacturing cost is. Verification whether the proposed algorithm of relative manufacturing costs estimation has been designed properly was made by comparison of the achieved from the algorithm results with those obtained from industry. This verification has indicated that in most cases both group of results are similar. Taking into account above it is possible to draw a conclusion that the Cost module might play significant role in design constructional process by adding an engineer at the selection stage of alternative gear wheels design. It should be remembered that real manufacturing cost can differ significantly according to available in a factory manufacturing techniques and stock of machine tools.

Reliability enhancement of APR + diverse protection system regarding common cause failures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oh, Y. G.; Kim, Y. M.; Yim, H. S.

2012-07-01

The Advanced Power Reactor Plus (APR +) nuclear power plant design has been developed on the basis of the APR1400 (Advanced Power Reactor 1400 MWe) to further enhance safety and economics. For the mitigation of Anticipated Transients Without Scram (ATWS) as well as Common Cause Failures (CCF) within the Plant Protection System (PPS) and the Emergency Safety Feature - Component Control System (ESF-CCS), several design improvement features have been implemented for the Diverse Protection System (DPS) of the APR + plant. As compared to the APR1400 DPS design, the APR + DPS has been designed to provide the Safety Injectionmore » Actuation Signal (SIAS) considering a large break LOCA accident concurrent with the CCF. Additionally several design improvement features, such as channel structure with redundant processing modules, and changes of system communication methods and auto-system test methods, are introduced to enhance the functional reliability of the DPS. Therefore, it is expected that the APR + DPS can provide an enhanced safety and reliability regarding possible CCF in the safety-grade I and C systems as well as the DPS itself. (authors)« less

Design and prototype tests of a seismic attenuation system for the advanced-LIGO output mode cleaner

NASA Astrophysics Data System (ADS)

Bertolini, A.; DeSalvo, R.; Galli, C.; Gennaro, G.; Mantovani, M.; Márka, S.; Sannibale, V.; Takamori, A.; Torrie, C.

2006-04-01

Both present LIGO and advanced LIGO (Ad-LIGO) will need an output mode cleaner (OMC) to reach the desired sensitivity. We designed a suitable OMC seismically attenuated optical table fitting to the existing vacuum chambers (horizontal access module, HAM chambers). The most straightforward and cost-effective solution satisfying the Ad-LIGO seismic attenuation specifications was to implement a single passive seismic attenuation stage, derived from the 'seismic attenuation system' (SAS) concept. We built and tested prototypes of all critical components. On the basis of these tests and past experience, we expect that the passive attenuation performance of this new design, called HAM-SAS, will match all requirements for the LIGO OMC, and all Ad-LIGO optical tables. Its performance can be improved, if necessary, by implementation of a simple active attenuation loop at marginal additional cost. The design can be easily modified to equip the LIGO basic symmetric chamber (BSC) chambers and leaves space for extensive performance upgrades for future evolutions of Ad-LIGO. Design parameters and prototype test results are presented.

Gadolinium-modulated 19F signals from Perfluorocarbon Nanoparticles as a New Strategy for Molecular Imaging

PubMed Central

Neubauer, Anne M.; Myerson, Jacob; Caruthers, Shelton D.; Hockett, Franklin D.; Winter, Patrick M.; Chen, Junjie; Gaffney, Patrick J.; Robertson, J. David; Lanza, Gregory M.; Wickline, Samuel A.

2008-01-01

Recent advances in the design of fluorinated nanoparticles for magnetic resonance molecular imaging have enabled specific detection of 19F nuclei, providing unique and quantifiable spectral signatures. However, a pressing need for signal enhancement exists because the total 19F in imaging voxels is often limited. By directly incorporating a relaxation agent (gadolinium) into the lipid monolayer that surrounds the perfluorocarbon, a marked augmentation of the 19F signal from 200nm nanoparticles was achieved. This design increases the magnetic relaxation rate of the 19F nuclei 4-fold at 1.5 T and effects a 125% increase in signal, an effect which is maintained when they are targeted to human plasma clots. By varying the surface concentration of gadolinium, the relaxation effect can be quantitatively modulated to tailor particle properties. This novel strategy dramatically improves the sensitivity and range of 19F MRI/MRS and forms the basis for designing contrast agents capable of sensing their surface chemistry. PMID:18956457

Design for pressure regulating components

NASA Technical Reports Server (NTRS)

Wichmann, H.

1973-01-01

The design development for Pressure Regulating Components included a regulator component trade-off study with analog computer performance verification to arrive at a final optimized regulator configuration for the Space Storable Propulsion Module, under development for a Jupiter Orbiter mission. This application requires the pressure regulator to be capable of long-term fluorine exposure. In addition, individual but basically identical (for purposes of commonality) units are required for separate oxidizer and fuel pressurization. The need for dual units requires improvement in the regulation accuracy over present designs. An advanced regulator concept was prepared featuring redundant bellows, all metallic/ceramic construction, friction-free guidance of moving parts, gas damping, and the elimination of coil springs normally used for reference forces. The activities included testing of actual size seat/poppet components to determine actual discharge coefficients and flow forces. The resulting data was inserted into the computer model of the regulator. Computer simulation of the propulsion module performance over two mission profiles indicated satisfactory minimization of propellant residual requirements imposed by regulator performance uncertainties.

Apollo experience report: Food systems

NASA Technical Reports Server (NTRS)

Smith, M. C., Jr.; Rapp, R. M.; Huber, C. S.; Rambaut, P. C.; Heidelbaugh, N. D.

1974-01-01

Development, delivery, and use of food systems in support of the Apollo 7 to 14 missions are discussed. Changes in design criteria for this unique program as mission requirements varied are traced from the baseline system that was established before the completion of the Gemini Program. Problems and progress in subsystem management, material selection, food packaging, development of new food items, menu design, and food-consumption methods under zero-gravity conditions are described. The effectiveness of various approaches in meeting food system objectives of providing flight crews with safe, nutritious, easy to prepare, and highly acceptable foods is considered. Nutritional quality and adequacy in maintaining crew health are discussed in relation to the establishment of nutritional criteria for future missions. Technological advances that have resulted from the design of separate food systems for the command module, the lunar module, The Mobile Quarantine Facility, and the Lunar Receiving Laboratory are presented for application to future manned spacecraft and to unique populations in earthbound situations.

Design and Development of Multi-Transceiver Lorafi Board consisting LoRa and ESP8266-Wifi Communication Module

NASA Astrophysics Data System (ADS)

Azmi, Noraini; Sudin, Sukhairi; Munirah Kamarudin, Latifah; Zakaria, Ammar; Visvanathan, Retnam; Chew Cheik, Goh; Mamduh Syed Zakaria, Syed Muhammad; Abdullah Alfarhan, Khudhur; Badlishah Ahmad, R.

2018-03-01

The advancement of Micro-Electro-Mechanical-Systems (MEMS), microcontroller technologies and the idea of Internet of Things (IoT) motivates the development of wireless modules (e.g. WiFi, Bluetooth, Zigbee, and LoRa) that are small and affordable. This paper aims to provide detailed information on the development of the LoRaFi board. The LoRaFi 1.0 is a multi-protocol communication board developed by Centre of Excellence for Advanced Sensor Technology (CEASTech). The board was developed for but not limited to monitor the indoor air quality. The board comprises two different wireless communication modules namely, Long-range technology (LoRa) and WiFi (using ESP8266). The board can be configured to communicate either using LoRa or WiFi or both. The board has been tested and the wireless communication operates successfully. Apart from LoRa, WiFi enables data to be forwarded to the cloud/server where the data can be stored for further data analysis. This helps provide users with real-time information on their smartphones or other applications. In the future, researchers will conduct tests to investigate the communication link quality. Newer version with reduced board size and additional wireless communication module will be developed in the future as to increase board flexibility and widen the range of applications that can use the board.

Advanced Mathematics 305--Optional Half Credit. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education, Winnipeg.

This manual outlines an advanced mathematics course for secondary school students in Manitoba (Canada). Included are eight different topics for a total of ten modules, with each module accounting for 18 40-minute periods. Teachers, or teachers and students cooperatively, should select the equivalent of five modules from the eight topics covered.…

Baseband-processed SS-TDMA communication system architecture and design concepts

NASA Technical Reports Server (NTRS)

Attwood, S.; Sabourin, D.

1982-01-01

The architecture and system design for a commercial satellite communications system planned for the 1990's was developed by Motorola for NASA's Lewis Research Center. The system provides data communications between individual users via trunking and customer premises service terminals utilizing a central switching satellite operating in a time-division multiple-access (TDMA) mode. The major elements of the design incorporating baseband processing include: demand-assigned multiple access reservation protocol, spectral utilization, system synchronization, modulation technique and forward error control implementation. Motorola's baseband processor design, which is being proven in a proof-of-concept advanced technology development, will perform data regeneration and message routing for individual users on-board the spacecraft.

Operational considerations of the Advanced Photovoltaic Solar Array

NASA Technical Reports Server (NTRS)

Stella, Paul M.; Kurland, Richard M.

1992-01-01

Issues affecting the long-term operational performance of the Advanced Photovoltaic Solar Array (APSA) are discussed, with particular attention given to circuit electrical integrity from shadowed and cracked cell modules. The successful integration of individual advanced array components provides a doubling of array specific performance from the previous NASA-developed advanced array (SAFE). Flight test modules both recently fabricated and under fabrication are described. The development of advanced high-performance blanket technology for future APSA enhancement is presented.

Operational considerations of the Advanced Photovoltaic Solar Array

NASA Astrophysics Data System (ADS)

Stella, Paul M.; Kurland, Richard M.

Issues affecting the long-term operational performance of the Advanced Photovoltaic Solar Array (APSA) are discussed, with particular attention given to circuit electrical integrity from shadowed and cracked cell modules. The successful integration of individual advanced array components provides a doubling of array specific performance from the previous NASA-developed advanced array (SAFE). Flight test modules both recently fabricated and under fabrication are described. The development of advanced high-performance blanket technology for future APSA enhancement is presented.

Micromirror-based real image laser automotive head-up display

NASA Astrophysics Data System (ADS)

Fan, Chao; He, Siyuan

2017-01-01

This paper reports a micromirror-based real image laser automotive head-up display (HUD), which overcomes the limitations of the previous designs by: (1) implementing an advanced display approach which is able to display sharp corners while the previous designs can only display curved lines such as to improve the display fidelity and (2) Optimizing the optical configuration to significantly reduce the HUD module size. The optical design in the HUD is simulated to choose the off-the-shelf concave lens. The vibration test is conducted to verify that the micromirror can survive 5 g. The prototype of the HUD system is fabricated and tested.

[Advances of portable electrocardiogram monitor design].

PubMed

Ding, Shenping; Wang, Yinghai; Wu, Weirong; Deng, Lingli; Lu, Jidong

2014-06-01

Portable electrocardiogram monitor is an important equipment in the clinical diagnosis of cardiovascular diseases due to its portable, real-time features. It has a broad application and development prospects in China. In the present review, previous researches on the portable electrocardiogram monitors have been arranged, analyzed and summarized. According to the characteristics of the electrocardiogram (ECG), this paper discusses the ergonomic design of the portable electrocardiogram monitor, including hardware and software. The circuit components and software modules were parsed from the ECG features and system functions. Finally, the development trend and reference are provided for the portable electrocardiogram monitors and for the subsequent research and product design.

Polymeric Biomaterials: Diverse Functions Enabled by Advances in Macromolecular Chemistry

PubMed Central

Liang, Yingkai; Li, Linqing; Scott, Rebecca A.; Kiick, Kristi L.

2017-01-01

Biomaterials have been extensively used to leverage beneficial outcomes in various therapeutic applications, such as providing spatial and temporal control over the release of therapeutic agents in drug delivery as well as engineering functional tissues and promoting the healing process in tissue engineering and regenerative medicine. This perspective presents important milestones in the development of polymeric biomaterials with defined structures and properties. Contemporary studies of biomaterial design have been reviewed with focus on constructing materials with controlled structure, dynamic functionality, and biological complexity. Examples of these polymeric biomaterials enabled by advanced synthetic methodologies, dynamic chemistry/assembly strategies, and modulated cell-material interactions have been highlighted. As the field of polymeric biomaterials continues to evolve with increased sophistication, current challenges and future directions for the design and translation of these materials are also summarized. PMID:29151616

Space Power Free-Piston Stirling Engine Scaling Study

NASA Technical Reports Server (NTRS)

Jones, D.

1989-01-01

The design feasibility study is documented of a single cylinder, free piston Stirling engine/linear alternator (FPSE/LA) power module generating 150 kW-electric (kW sub e), and the determination of the module's maximum feasible power level. The power module configuration was specified to be a single cylinder (single piston, single displacer) FPSE/LA, with tuning capacitors if required. The design requirements were as follows: (1) Maximum electrical power output; (2) Power module thermal efficiency equal to or greater than 20 percent at a specific mass of 5 to 8 kg/kW(sub e); (3) Heater wall temperature/cooler wall temperature = 1050 K/525 K; (4) Sodium heat-pipe heat transport system, pumped loop NaK (sodium-potassium eutectic mixture) rejection system; (5) Maximum power module vibration amplitude = 0.0038 cm; and (6) Design life = 7 years (60,000 hr). The results show that a single cylinder FPSE/LA is capable of meeting program goals and has attractive scaling attributes over the power range from 25 to 150 kW(sub e). Scaling beyond the 150 kW(sub e) power level, the power module efficiency falls and the power module specific mass reaches 10 kg/kW(sub e) at a power output of 500 kW(sub e). A discussion of scaling rules for the engine, alternator, and heat transport systems is presented, along with a detailed description of the conceptual design of a 150 kW(sub e) power module that meets the requirements. Included is a discussion of the design of a dynamic balance system. A parametric study of power module performance conducted over the power output range of 25 to 150 kW(sub e) for temperature ratios of 1.7, 2.0, 2.5, and 3.0 is presented and discussed. The results show that as the temperature ratio decreases, the efficiency falls and specific mass increases. At a temperature ratio of 1.7, the 150 kW(sub e) power module cannot satisfy both efficiency and specific mass goals. As the power level increases from 25 to 150 kW(sub e) at a fixed temperature ratio, power module efficiency is seen to increase slightly, but at the expense of increased specific mass. An empirical equation relating power module thermal efficiency as a function of power module specific mass, power output, and temperature ratio is developed. Alternative configurations to the single cylinder, direct coupled linear alternator approach are also evaluated, but are shown to have technical drawbacks that lessen their attractiveness. The dynamic balance assembly mass (moving mass and structure) represents 20 to 30 percent of the total single cylinder power module mass. Joining two modules in a balanced opposed configuration eliminates the need for the balancer, and a hot end junction can be made without significant addition of structural mass. Recommendations are made for evaluation of advanced heat pipe concepts, tests of radial flow heat exchangers, and evaluation of high temperature alternator materials.

Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation

PubMed Central

Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A.; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R.; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D.; Alivisatos, A. Paul; Meitl, Matthew; Burroughs, Scott; Hussain, Muhammad Mustafa; Lee, Jeong Chul; Nuzzo, Ralph G.; Rogers, John A.

2016-01-01

Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III–V semiconductor technologies. In this CPV+ scheme (“+” denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV+ modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation. PMID:27930331

Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation

DOE PAGES

Lee, Kyu-Tae; Yao, Yuan; He, Junwen; ...

2016-12-05

Emerging classes ofconcentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PVmore » conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV + scheme ("+" denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV + modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.« less

Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation

NASA Astrophysics Data System (ADS)

Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A.; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R.; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D.; Alivisatos, A. Paul; Meitl, Matthew; Burroughs, Scott; Mustafa Hussain, Muhammad; Lee, Jeong Chul; Nuzzo, Ralph G.; Rogers, John A.

2016-12-01

Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV+ scheme (“+” denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV+ modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.

Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation.

PubMed

Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D; Alivisatos, A Paul; Meitl, Matthew; Burroughs, Scott; Hussain, Muhammad Mustafa; Lee, Jeong Chul; Nuzzo, Ralph G; Rogers, John A

2016-12-20

Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV + scheme ("+" denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV + modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.

GPM Avionics Module Heat Pipes Design and Performance Test Results

NASA Technical Reports Server (NTRS)

Ottenstein, Laura; DeChristopher, Mike

2011-01-01

The Global Precipitation Measurement (GPM) mission is an international network of satellites that provide the next-generation global observations of rain and snow. The GPM core satellite carries an advanced radar / radiometer system to measure precipitation from space and serve as a reference standard to unify precipitation measurements from a constellation of research and operational satellites. Through improved measurements of precipitation globally, the GPM mission will help to advance our understanding of Earth's water and energy cycle, improve forecasting of extreme events that cause natural hazards and disasters, and extend current capabilities in using accurate and timely information of precipitation to directly benefit society. The avionics module on the core satellite contains a number of electronics boxes which are cooled by a network of aluminum/ammonia heat pipes and a honeycomb radiator which contains thirteen embedded aluminum/ammonia heat pipes. All heat pipes were individually tested by the vendor (Advanced Cooling Technologies, Inc.) prior to delivery. Following delivery to NASA, the flight avionics radiator and the flight spare transport heat pipes were mounted to flight-like test structure and a system level thermal vacuum test was performed. This test, which used simulators in place of all electronics boxes, was done to verify the operation of the thermal control system as a whole. This presentation will discuss the design of the avionics module heat pipes, and then discuss performance tests results for the individual heat pipes prior to delivery and for the system level thermal vacuum test. All heat pipes met their performance requirements. However, it was found that the power was too low in some instances to start all of the smaller radiator spreader heat pipes when they were tested in a reflux configuration (which is the nominal test configuration). Although this lowered the efficiency of the radiator somewhat, it did not impact the operating temperatures of the electronics boxes.

Direct evidence for stress-induced transformation between coexisting multiple martensites in a Ni-Mn-Ga multifunctional alloy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, L.; Cong, D. Y.; Wang, Z. L.

2015-07-08

The structural response of coexisting multiple martensites to stress field in a Ni-Mn-Ga multifunctional alloy was investigated by the in situ high-energy x-ray diffraction technique. Stress-induced transformation between coexisting multiple martensites was observed at 110 K, at which five-layered modulated (5M), seven-layered modulated (7M) and non-modulated (NM) martensites coexist. We found that a tiny stress of as low as 0.5 MPa could trigger the transformation from 5M and 7M martensites to NM martensite and this transformation is partly reversible. Besides the transformation between coexisting multiple martensites, rearrangement of martensite variants also occurs during loading, at least at high stress levels.more » The present study is instructive for designing advanced multifunctional alloys with easy actuation.« less

Direct evidence for stress-induced transformation between coexisting multiple martensites in a Ni-Mn-Ga multifunctional alloy

NASA Astrophysics Data System (ADS)

Huang, L.; Cong, D. Y.; Wang, Z. L.; Nie, Z. H.; Dong, Y. H.; Zhang, Y.; Ren, Y.; Wang, Y. D.

2015-07-01

The structural response of coexisting multiple martensites to stress field in a Ni-Mn-Ga multifunctional alloy was investigated by the in situ high-energy x-ray diffraction technique. Stress-induced transformation between coexisting multiple martensites was observed at 110 K, at which five-layered modulated (5M), seven-layered modulated (7M) and non-modulated (NM) martensites coexist. We found that a tiny stress of as low as 0.5 MPa could trigger the transformation from 5M and 7M martensites to NM martensite and this transformation is partly reversible. Besides the transformation between coexisting multiple martensites, rearrangement of martensite variants also occurs during loading, at least at high stress levels. The present study is instructive for designing advanced multifunctional alloys with easy actuation.

Direct evidence for stress-induced transformation between coexisting multiple martensites in a Ni-Mn-Ga multifunctional alloy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, L.; Cong, D. Y.; Wang, Z. L.

2015-06-03

The structural response of coexisting multiple martensites to stress field in a Ni-Mn-Ga multifunctional alloy was investigated by the in situ high-energy x-ray diffraction technique. Stress-induced transformation between coexisting multiple martensites was observed at 110 K, at which five-layered modulated (5M), seven-layered modulated (7M) and non-modulated (NM) martensites coexist. We found that a tiny stress of as low as 0.5 MPa could trigger the transformation from 5M and 7M martensites to NM martensite and this transformation is partly reversible. Besides the transformation between coexisting multiple martensites, rearrangement of martensite variants also occurs during loading, at least at high stress levels.more » The present study is instructive for designing advanced multifunctional alloys with easy actuation.« less

Reliability Technology to Achieve Insertion of Advanced Packaging (RELTECH) program

NASA Astrophysics Data System (ADS)

Fayette, Daniel F.; Speicher, Patricia; Stoklosa, Mark J.; Evans, Jillian V.; Evans, John W.; Gentile, Mike; Pagel, Chuck A.; Hakim, Edward

1993-08-01

A joint military-commercial effort to evaluate multichip module (MCM) structures is discussed. The program, Reliability Technology to Achieve Insertion of Advanced Packaging (RELTECH), has been designed to identify the failure mechanisms that are possible in MCM structures. The RELTECH test vehicles, technical assessment task, product evaluation plan, reliability modeling task, accelerated and environmental testing, and post-test physical analysis and failure analysis are described. The information obtained through RELTECH can be used to address standardization issues, through development of cost effective qualification and appropriate screening criteria, for inclusion into a commercial specification and the MIL-H-38534 general specification for hybrid microcircuits.

GPM Avionics Module Heat Pipes Design and Performance Test Results

NASA Technical Reports Server (NTRS)

Ottenstein, Laura; DeChristopher, Mike

2012-01-01

GPM is a satellite constellation to study precipitation formed from a partnership between NASA and the Japanese Aerospace Exploration Agency (JAXA). The GPM Core Observatory, being developed and tested at GSFC, serves as a reference standard to unify precipitation measurements from the GPM satellite constellation. The Core Observatory carries an advanced radar/radiometer system to measure precipitation from space. The scientific data gained from GPM will benefit both NASA and JAXA by advancing our understanding of Earth's water and energy cycle, improving forecasts of extreme weather events, and extending our current capabilities in using accurate and timely precipitation information to benefit society.

Advanced light source master oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lo, C.C.; Taylor, B.; Baptiste, K.

1989-03-01

The Master Oscillator of the Advanced Light Source operates at a frequency of 499.654 MHz which is the 328th harmonic of the storage ring. The oscillator is capable of providing up to a maximum of {plus minus} 500 KHz frequency deviation for various experimental purposes. Provisions for external signal injection as well as using an external signal source have been designed into the unit. A power distribution system has also been included to provide signals for various parts of the ALS machine and user requirements. The Master Oscillator is made up with modules housed in a Euro chassis. 4 refs.,more » 7 figs.« less

The kinematic Stirling engine as an energy conversion subsystem for paraboloidal dish solar thermal plants

NASA Technical Reports Server (NTRS)

Bowyer, J. M.

1984-01-01

The potential of a suitably designed and economically manufactured Stirling engine as the energy conversion subsystem of a paraboloidal dish-Stirling solar thermal power module was estimated. Results obtained by elementary cycle analyses were shown to match quite well the performance characteristics of an advanced kinematic Stirling engine, the United Stirling P-40, as established by current prototypes of the engine and by a more sophisticated analytic model of its advanced derivative. In addition to performance, brief consideration was given to other Stirling engine criteria such as durability, reliability, and serviceability. Production costs were not considered here.

Reliability Technology to Achieve Insertion of Advanced Packaging (RELTECH) program

NASA Technical Reports Server (NTRS)

Fayette, Daniel F.; Speicher, Patricia; Stoklosa, Mark J.; Evans, Jillian V.; Evans, John W.; Gentile, Mike; Pagel, Chuck A.; Hakim, Edward

1993-01-01

A joint military-commercial effort to evaluate multichip module (MCM) structures is discussed. The program, Reliability Technology to Achieve Insertion of Advanced Packaging (RELTECH), has been designed to identify the failure mechanisms that are possible in MCM structures. The RELTECH test vehicles, technical assessment task, product evaluation plan, reliability modeling task, accelerated and environmental testing, and post-test physical analysis and failure analysis are described. The information obtained through RELTECH can be used to address standardization issues, through development of cost effective qualification and appropriate screening criteria, for inclusion into a commercial specification and the MIL-H-38534 general specification for hybrid microcircuits.

A Research Module for the Organic Chemistry Laboratory: Multistep Synthesis of a Fluorous Dye Molecule

PubMed Central

2014-01-01

A multi-session research-like module has been developed for use in the undergraduate organic teaching laboratory curriculum. Students are tasked with planning and executing the synthesis of a novel fluorous dye molecule and using it to explore a fluorous affinity chromatography separation technique, which is the first implementation of this technique in a teaching laboratory. Key elements of the project include gradually introducing students to the use of the chemical literature to facilitate their searching, as well as deliberate constraints designed to force them to think critically about reaction design and optimization in organic chemistry. The project also introduces students to some advanced laboratory practices such as Schlenk techniques, degassing of reaction mixtures, affinity chromatography, and microwave-assisted chemistry. This provides students a teaching laboratory experience that closely mirrors authentic synthetic organic chemistry practice in laboratories throughout the world. PMID:24501431

Sub-picowatt/kelvin resistive thermometry for probing nanoscale thermal transport.

PubMed

Zheng, Jianlin; Wingert, Matthew C; Dechaumphai, Edward; Chen, Renkun

2013-11-01

Advanced instrumentation in thermometry holds the key for experimentally probing fundamental heat transfer physics. However, instrumentation with simultaneously high thermometry resolution and low parasitic heat conduction is still not available today. Here we report a resistive thermometry scheme with ~50 μK temperature resolution and ~0.25 pW/K thermal conductance resolution, which is achieved through schemes using both modulated heating and common mode noise rejection. The suspended devices used herein have been specifically designed to possess short thermal time constants and minimal attenuation effects associated with the modulated heating current. Furthermore, we have systematically characterized the parasitic background heat conductance, which is shown to be significantly reduced using the new device design and can be effectively eliminated using a "canceling" scheme. Our results pave the way for probing fundamental nanoscale thermal transport processes using a general scheme based on resistive thermometry.

A Research Module for the Organic Chemistry Laboratory: Multistep Synthesis of a Fluorous Dye Molecule.

PubMed

Slade, Michael C; Raker, Jeffrey R; Kobilka, Brandon; Pohl, Nicola L B

2014-01-14

A multi-session research-like module has been developed for use in the undergraduate organic teaching laboratory curriculum. Students are tasked with planning and executing the synthesis of a novel fluorous dye molecule and using it to explore a fluorous affinity chromatography separation technique, which is the first implementation of this technique in a teaching laboratory. Key elements of the project include gradually introducing students to the use of the chemical literature to facilitate their searching, as well as deliberate constraints designed to force them to think critically about reaction design and optimization in organic chemistry. The project also introduces students to some advanced laboratory practices such as Schlenk techniques, degassing of reaction mixtures, affinity chromatography, and microwave-assisted chemistry. This provides students a teaching laboratory experience that closely mirrors authentic synthetic organic chemistry practice in laboratories throughout the world.

An Information NEXUS: The NASA Global Hawk Link Module

NASA Technical Reports Server (NTRS)

Sullivan, D. V.

2012-01-01

The Link Module described in this paper was first developed for the NASA Global Hawk Pacific Mission (GloPAC), four flights of 30 hour duration, supporting the Aura Validation Experiment (AVE). Its second use was during the Genesis and Rapid Intensification Processes (GRIP) experiment, a NASA Earth Science field experiment to better understand how tropical storms form and develop into major hurricanes. In these missions, the Link module negotiated all communication over the high bandwidth Ku satellite link, archived al the science data from onboard experiments in a spatially enable database, routed command and control of the instruments from the Global Hawk Operations Center, and retransmitted select data sets directly to experimenters control and analysis systems. The availability of aggregated information from collections of sensors, and remote control capabilities, in real-time, is revolutionizing the way Airborne Science is being conducted. Also described is the next generation Link Module now being designed and tested to support the NASA Earth Venture missions, the Hurricane and Severe Storm Sentinel (HS3) mission, and Airborne Tropical Tropopause Experiment (ATTREX) mission. Advanced data fusion technologies being developed will further advance the Scientific productivity, flexibility and robustness of these systems. Historically, the Link module evolved from the instrument and communication interface controller used by NASA's Pathfinder and Pathfinder plus solar powered UAS's in the late 1990's. It later was expanded for use in the AIRDAS four channel scanner flown on the NASA Altus UAS, and then again to a module in the AMS twelve channel multispectral scanner flying on the NASA (Predator-b) Ikhana UAS. The current system is the next step in the evolution, a multi board system packaged in a Curtiss Wright MIL-spec, flight qualified enclosure.

Enhancing reflective practice through online learning: impact on clinical practice

PubMed Central

Sim, J; Radloff, A

2008-01-01

Purpose Traditionally, radiographers and radiation therapists function in a workplace environment that is protocol-driven with limited functional autonomy. The workplace promotes a culture of conformity and discourages practitioners from reflective and critical thinking, essential attributes for continuing learning and advancing workplace practices. As part of the first author’s doctoral study, a continuing professional development (CPD) educational framework was used to design and implement an online module for radiation therapists’ CPD activities. The study aimed to determine if it is possible to enhance healthcare practitioners’ reflective practice via online learning and to establish the impact of reflective learning on clinical practice. Materials and methods The objectives of the online module were to increase radiation therapists’ knowledge in planning for radiation therapy for the breast by assisting them engage in reflective practice. The cyclical process of action research was used to pilot the module twice with two groups of volunteer radiation therapists (twenty-six participants) from Australia, New Zealand and Canada. Results The online module was evaluated using Kirkpatrick’s four-level evaluation model. Evidence indicated that participants were empowered as a result of participation in the module. They began reflecting in the workplace while assuming a more proactive role and increased clinical responsibilities, engaged colleagues in collaborative reflections and adopted evidence-based approaches in advancing clinical practices. Conclusion The study shows that it is possible to assist practitioners engage in reflective practice using an online CPD educational framework. Participants were able to apply the reflective learning they had developed in their workplace. As a result of their learning, they felt empowered to continue to effect changes in their workplace beyond the cessation of the online module. PMID:21614319

Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). Safety Section: Modules 1-3. Instructor Book.

ERIC Educational Resources Information Center

Averitt, Sallie D.

These three modules, which were developed for use by instructors in a manufacturing firm's advanced technical preparation program, contain the materials required to present the safety section of the plant's adult-oriented, job-specific competency-based training program. The 3 modules contain 12 lessons on the following topics: lockout/tagout…

Assessing Advanced High School and Undergraduate Students' Thinking Skills: The Chemistry--From the Nanoscale to Microelectronics Module

ERIC Educational Resources Information Center

Dori, Yehudit Judy; Dangur, Vered; Avargil, Shirly; Peskin, Uri

2014-01-01

Chemistry students in Israel have two options for studying chemistry: basic or honors (advanced placement). For instruction in high school honors chemistry courses, we developed a module focusing on abstract topics in quantum mechanics: Chemistry--From the Nanoscale to Microelectronics. The module adopts a visual-conceptual approach, which…

A Comprehensive Microfluidics Device Construction and Characterization Module for the Advanced Undergraduate Analytical Chemistry Laboratory

ERIC Educational Resources Information Center

Piunno, Paul A. E.; Zetina, Adrian; Chu, Norman; Tavares, Anthony J.; Noor, M. Omair; Petryayeva, Eleonora; Uddayasankar, Uvaraj; Veglio, Andrew

2014-01-01

An advanced analytical chemistry undergraduate laboratory module on microfluidics that spans 4 weeks (4 h per week) is presented. The laboratory module focuses on comprehensive experiential learning of microfluidic device fabrication and the core characteristics of microfluidic devices as they pertain to fluid flow and the manipulation of samples.…

Development of a Lunar Consumables Storage and Distribution Depot

NASA Technical Reports Server (NTRS)

Mueller, Robert P.; Notardonato, William

2004-01-01

NASA is in the preliminary planning stages for a future lunar base as a response to President George W. Bush's recent announcement of a new sustained exploration program beyond low earth orbit. Kennedy Space Center engineers are supporting this program by utilizing experience in Spaceport system design and operations to help develop a Lunar Consumables Depot. This depot will store propellants, life support fluids, and other consumables either transported from Earth or manufactured from In Situ resources. The depot will distribute these consumables in an energy efficient manner to end users including spacecraft, habitation modules, and rovers. This paper addresses some of the changes to lunar base architecture design as a result of advances in knowledge of lunar resources over the past 35 years, as well as technology advances in the area of In Situ Resource Utilization and consumable storage and distribution. A general system level description of the depot will be presented, including overall design philosophy and high level requirements. Finally, specific subsystem technologies that have been or will be developed by KSC will be addressed. Examples of these technologies are automated umbilicals, cryogenic refrigerators, novel storage vessels, advanced heat switches and heat exchangers, and self healing gaskets and wires.

Artificial gravity Mars spaceship

NASA Technical Reports Server (NTRS)

Clark, Benton C.

1989-01-01

Experience gained in the study of artificial gravity for a manned trip to Mars is reviewed, and a snowflake-configured interplanetary vehicle cluster of habitat modules, descent vehicles, and propulsion systems is presented. An evolutionary design is described which permits sequential upgrading from five to nine crew members, an increase of landers from one to as many a three per mission, and an orderly, phased incorporation of advanced technologies as they become available.

An Overview of Spray Modeling With OpenNCC and its Application to Emissions Predictions of a LDI Combustor at High Pressure

NASA Technical Reports Server (NTRS)

Raju, M. S.

2016-01-01

The open national combustion code (Open- NCC) is developed with the aim of advancing the current multi-dimensional computational tools used in the design of advanced technology combustors. In this paper we provide an overview of the spray module, LSPRAY-V, developed as a part of this effort. The spray solver is mainly designed to predict the flow, thermal, and transport properties of a rapidly evaporating multi-component liquid spray. The modeling approach is applicable over a wide-range of evaporating conditions (normal, superheat, and supercritical). The modeling approach is based on several well-established atomization, vaporization, and wall/droplet impingement models. It facilitates large-scale combustor computations through the use of massively parallel computers with the ability to perform the computations on either structured & unstructured grids. The spray module has a multi-liquid and multi-injector capability, and can be used in the calculation of both steady and unsteady computations. We conclude the paper by providing the results for a reacting spray generated by a single injector element with 600 axially swept swirler vanes. It is a configuration based on the next-generation lean-direct injection (LDI) combustor concept. The results include comparisons for both combustor exit temperature and EINOX at three different fuel/air ratios.

Cardiac autonomic modulation impairments in advanced breast cancer patients.

PubMed

Arab, Claudia; Vanderlei, Luiz Carlos Marques; da Silva Paiva, Laércio; Fulghum, Kyle Levi; Fristachi, Carlos Elias; Nazario, Afonso Celso Pinto; Elias, Simone; Gebrim, Luiz Henrique; Ferreira Filho, Celso; Gidron, Yori; Ferreira, Celso

2018-05-02

To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. This cross-sectional study included women (30-69 years old) with primary diagnosis of breast cancer and women with benign breast tumors. We evaluated cardiac modulation by heart rate variability and assessed factors of anxiety, depression, physical activity, and other relevant medical variables. Patients were divided into three groups based on TNM staging of cancer severity: early-stage cancer (n = 42), advanced-stage cancer (n = 37), or benign breast tumors to serve as a control (n = 37). We analyzed heart rate variability in time and frequency domains. The advanced-stage cancer group had lower vagal modulation than early-stage and benign groups; also, the advance-stage group had lower overall heart rate variability when compared to benign conditions. Heart rate variability was influenced by age, menopausal status, and BMI. Heart rate variability seems to be a promising, non-invasive tool for early diagnosis of autonomic dysfunction in breast cancer and detection of cardiovascular impairments at cancer diagnosis. Cardiac autonomic modulation is inversely associated with breast cancer staging.

Real-Time Closed Loop Modulated Turbine Cooling

NASA Technical Reports Server (NTRS)

Shyam, Vikram; Culley, Dennis E.; Eldridge, Jeffrey; Jones, Scott; Woike, Mark; Cuy, Michael

2014-01-01

It has been noted by industry that in addition to dramatic variations of temperature over a given blade surface, blade-to-blade variations also exist despite identical design. These variations result from manufacturing variations, uneven wear and deposition over the life of the part as well as limitations in the uniformity of coolant distribution in the baseline cooling design. It is proposed to combine recent advances in optical sensing, actuation, and film cooling concepts to develop a workable active, closed-loop modulated turbine cooling system to improve by 10 to 20 the turbine thermal state over the flight mission, to improve engine life and to dramatically reduce turbine cooling air usage and aircraft fuel burn. A reduction in oxides of nitrogen (NOx) can also be achieved by using the excess coolant to improve mixing in the combustor especially for rotorcraft engines. Recent patents filed by industry and universities relate to modulating endwall cooling using valves. These schemes are complex, add weight and are limited to the endwalls. The novelty of the proposed approach is twofold 1) Fluidic diverters that have no moving parts are used to modulate cooling and can operate under a wide range of conditions and environments. 2) Real-time optical sensing to map the thermal state of the turbine has never been attempted in realistic engine conditions.

Systems and operations - Living with complexity and growth

NASA Astrophysics Data System (ADS)

Hook, W. R.

1983-03-01

Since the space station concept currently being developed by NASA calls for system updates and additions over a period of at least ten years following launch, attention must be given to the interfaces between station elements. Efforts have begun to develop generic fault detection, isolation, and correction techniques that could simplify on-orbit operations, maintenance and repair. An integrated hydrogen-oxygen system has been identified as the feature promising the greatest reduction in resupply costs. Scavenging excess fuel from the Space Shuttle's internal and external tanks, and using leftover Shuttle payload for fluid tankage, could supply hydrogen and oxygen for consumption in the form of propellants, fuel cell electricity, and life support gases. Advancements in cryogenic fluid management and storage technology are the keys to the design of this integrated system. Attention is given to the Interactive Design and Evaluation of Advanced Spacecraft computer-aided design and analysis system, which allows system engineers to study the integration problems presented by 40 technical modules.

Liquid Oxygen/Liquid Methane Propulsion and Cryogenic Advanced Development

NASA Technical Reports Server (NTRS)

Klem, Mark D.; Smith, Timothy D.; Wadel, Mary F.; Meyer, Michael L.; Free, James M.; Cikanek, Harry A., III

2011-01-01

Exploration Systems Architecture Study conducted by NASA in 2005 identified the liquid oxygen (LOx)/liquid methane (LCH4) propellant combination as a prime candidate for the Crew Exploration Vehicle Service Module propulsion and for later use for ascent stage propulsion of the lunar lander. Both the Crew Exploration Vehicle and Lunar Lander were part the Constellation architecture, which had the objective to provide global sustained lunar human exploration capability. From late 2005 through the end of 2010, NASA and industry matured advanced development designs for many components that could be employed in relatively high thrust, high delta velocity, pressure fed propulsion systems for these two applications. The major investments were in main engines, reaction control engines, and the devices needed for cryogenic fluid management such as screens, propellant management devices, thermodynamic vents, and mass gauges. Engine and thruster developments also included advanced high reliability low mass igniters. Extensive tests were successfully conducted for all of these elements. For the thrusters and engines, testing included sea level and altitude conditions. This advanced development provides a mature technology base for future liquid oxygen/liquid methane pressure fed space propulsion systems. This paper documents the design and test efforts along with resulting hardware and test results.

The AP1000{sup R} China projects move forward to construction completion and equipment installation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrop, G.

2012-07-01

The AP1000 design is the only Generation III+ technology to receive design certification from the U.S. Nuclear Regulatory Commission. This evolutionary design provides the highest safety and performance standards and has several distinct advantages over other designs, including improved operations and reduced construction schedule risks through the use of modern, modular, engineering principles that allow construction and fabrication tasks traditionally performed in sequence to be undertaken in parallel. Since the first granting of Design Certification in 2005 by the NRC, the AP1000 design has been modified to meet emergent NRC requirements such as those requiring the design to withstand themore » impact of an aircraft crash. Both domestic and foreign utilities have turned to the Westinghouse AP1000 plant design to meet their near - and long-term sustainable energy needs. The first ever deployment of this advanced U.S. nuclear power technology began in China in 2007 with the award of a contract to build four AP1000 units, constructed in pairs at the coastal sites of Sanmen (Zhejiang Province) and Haiyang (Shandong Province). Currently, all four units are at an advanced stage of construction. The commercial operation date for Sanmen Unit 1 is November 2013 followed by Haiyang Unit 1 being operational in May 2014. Construction and equipment manufacture is at an advanced stage. Sanmen Unit 1 equipment that has been delivered includes the reactor vessel, the reactor vessel closure head, the passive residual heat removal heat exchanger, the integrated head package, the polar crane, and the refueling machine. The steam generators are also completed. The RV was installed within the containment vessel building in September 2011. The installation of this major equipment will allow the setting of the containment vessel top head. Haiyang Unit 1 is also achieving significant progress. Significant benefits continue to be realized as a result of lessons learned and experience gained from the first-of-a-kind activities for Sanmen Unit 1 and AP1000 equipment design and manufacturing. For example, the nuclear island basemat at Haiyang Units 1 and 2 and Sanmen Unit 2 was laid in less time than that of Sanmen Unit 1, the ultra-large steam generator and RV forging lead times were reduced for the follow on units, and the fabrication of the auxiliary building module for Haiyang Unit 1 took less time than for the Sanmen first unit. These benefits are also being realized by the United States AP1000 project construction and fabrication modules, and equipment. Some difficulties arise from building this first-of-a-kind (advanced passive) type of plant; however, these difficulties are being overcome and the overall schedule remains achievable. (authors)« less

Ferroelastic modulation and the Bloch formalism

DOE PAGES

Mascarenhas, Angelo; Fluegel, Brian; Bhusal, Lekhnath

2017-06-07

The key to the development of advanced materials is to understand their electronic structure-property relationship. Utilization of this understanding to design new electronic materials with desired properties led to modern epitaxial growth approaches for synthesizing artificial lattices, which for almost half a century have become the mainstay of electronic and photonic technologies. In contrast to previous scalar modulation approaches, we now study synthetic crystal lattices that have a tensor artificial modulation and develop a theory for photons and conduction band states in these lattices in a regime with an unusual departure from the familiar consequences of translational symmetry and Bloch'smore » theorem. As a result, this study reveals that a nonmagnetic crystal lattice modulated by a purely geometrical orientational superlattice potential can lead to localized states or to spiral states for electrons and photons, as well as weakly or strongly localized states that could be used to markedly slow down the propagation of light and for optical energy storage applications.« less

Ferroelastic modulation and the Bloch formalism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mascarenhas, Angelo; Fluegel, Brian; Bhusal, Lekhnath

The key to the development of advanced materials is to understand their electronic structure-property relationship. Utilization of this understanding to design new electronic materials with desired properties led to modern epitaxial growth approaches for synthesizing artificial lattices, which for almost half a century have become the mainstay of electronic and photonic technologies. In contrast to previous scalar modulation approaches, we now study synthetic crystal lattices that have a tensor artificial modulation and develop a theory for photons and conduction band states in these lattices in a regime with an unusual departure from the familiar consequences of translational symmetry and Bloch'smore » theorem. As a result, this study reveals that a nonmagnetic crystal lattice modulated by a purely geometrical orientational superlattice potential can lead to localized states or to spiral states for electrons and photons, as well as weakly or strongly localized states that could be used to markedly slow down the propagation of light and for optical energy storage applications.« less

Next-generation fiber lasers enabled by high-performance components

NASA Astrophysics Data System (ADS)

Kliner, D. A. V.; Victor, B.; Rivera, C.; Fanning, G.; Balsley, D.; Farrow, R. L.; Kennedy, K.; Hampton, S.; Hawke, R.; Soukup, E.; Reynolds, M.; Hodges, A.; Emery, J.; Brown, A.; Almonte, K.; Nelson, M.; Foley, B.; Dawson, D.; Hemenway, D. M.; Urbanek, W.; DeVito, M.; Bao, L.; Koponen, J.; Gross, K.

2018-02-01

Next-generation industrial fiber lasers enable challenging applications that cannot be addressed with legacy fiber lasers. Key features of next-generation fiber lasers include robust back-reflection protection, high power stability, wide power tunability, high-speed modulation and waveform generation, and facile field serviceability. These capabilities are enabled by high-performance components, particularly pump diodes and optical fibers, and by advanced fiber laser designs. We summarize the performance and reliability of nLIGHT diodes, fibers, and next-generation industrial fiber lasers at power levels of 500 W - 8 kW. We show back-reflection studies with up to 1 kW of back-reflected power, power-stability measurements in cw and modulated operation exhibiting sub-1% stability over a 5 - 100% power range, and high-speed modulation (100 kHz) and waveform generation with a bandwidth 20x higher than standard fiber lasers. We show results from representative applications, including cutting and welding of highly reflective metals (Cu and Al) for production of Li-ion battery modules and processing of carbon fiber reinforced polymers.

Modular Aero-Propulsion System Simulation

NASA Technical Reports Server (NTRS)

Parker, Khary I.; Guo, Ten-Huei

2006-01-01

The Modular Aero-Propulsion System Simulation (MAPSS) is a graphical simulation environment designed for the development of advanced control algorithms and rapid testing of these algorithms on a generic computational model of a turbofan engine and its control system. MAPSS is a nonlinear, non-real-time simulation comprising a Component Level Model (CLM) module and a Controller-and-Actuator Dynamics (CAD) module. The CLM module simulates the dynamics of engine components at a sampling rate of 2,500 Hz. The controller submodule of the CAD module simulates a digital controller, which has a typical update rate of 50 Hz. The sampling rate for the actuators in the CAD module is the same as that of the CLM. MAPSS provides a graphical user interface that affords easy access to engine-operation, engine-health, and control parameters; is used to enter such input model parameters as power lever angle (PLA), Mach number, and altitude; and can be used to change controller and engine parameters. Output variables are selectable by the user. Output data as well as any changes to constants and other parameters can be saved and reloaded into the GUI later.

VASIR: An Open-Source Research Platform for Advanced Iris Recognition Technologies.

PubMed

Lee, Yooyoung; Micheals, Ross J; Filliben, James J; Phillips, P Jonathon

2013-01-01

The performance of iris recognition systems is frequently affected by input image quality, which in turn is vulnerable to less-than-optimal conditions due to illuminations, environments, and subject characteristics (e.g., distance, movement, face/body visibility, blinking, etc.). VASIR (Video-based Automatic System for Iris Recognition) is a state-of-the-art NIST-developed iris recognition software platform designed to systematically address these vulnerabilities. We developed VASIR as a research tool that will not only provide a reference (to assess the relative performance of alternative algorithms) for the biometrics community, but will also advance (via this new emerging iris recognition paradigm) NIST's measurement mission. VASIR is designed to accommodate both ideal (e.g., classical still images) and less-than-ideal images (e.g., face-visible videos). VASIR has three primary modules: 1) Image Acquisition 2) Video Processing, and 3) Iris Recognition. Each module consists of several sub-components that have been optimized by use of rigorous orthogonal experiment design and analysis techniques. We evaluated VASIR performance using the MBGC (Multiple Biometric Grand Challenge) NIR (Near-Infrared) face-visible video dataset and the ICE (Iris Challenge Evaluation) 2005 still-based dataset. The results showed that even though VASIR was primarily developed and optimized for the less-constrained video case, it still achieved high verification rates for the traditional still-image case. For this reason, VASIR may be used as an effective baseline for the biometrics community to evaluate their algorithm performance, and thus serves as a valuable research platform.

VASIR: An Open-Source Research Platform for Advanced Iris Recognition Technologies

PubMed Central

Lee, Yooyoung; Micheals, Ross J; Filliben, James J; Phillips, P Jonathon

2013-01-01

The performance of iris recognition systems is frequently affected by input image quality, which in turn is vulnerable to less-than-optimal conditions due to illuminations, environments, and subject characteristics (e.g., distance, movement, face/body visibility, blinking, etc.). VASIR (Video-based Automatic System for Iris Recognition) is a state-of-the-art NIST-developed iris recognition software platform designed to systematically address these vulnerabilities. We developed VASIR as a research tool that will not only provide a reference (to assess the relative performance of alternative algorithms) for the biometrics community, but will also advance (via this new emerging iris recognition paradigm) NIST’s measurement mission. VASIR is designed to accommodate both ideal (e.g., classical still images) and less-than-ideal images (e.g., face-visible videos). VASIR has three primary modules: 1) Image Acquisition 2) Video Processing, and 3) Iris Recognition. Each module consists of several sub-components that have been optimized by use of rigorous orthogonal experiment design and analysis techniques. We evaluated VASIR performance using the MBGC (Multiple Biometric Grand Challenge) NIR (Near-Infrared) face-visible video dataset and the ICE (Iris Challenge Evaluation) 2005 still-based dataset. The results showed that even though VASIR was primarily developed and optimized for the less-constrained video case, it still achieved high verification rates for the traditional still-image case. For this reason, VASIR may be used as an effective baseline for the biometrics community to evaluate their algorithm performance, and thus serves as a valuable research platform. PMID:26401431

Thin EFG octagons

NASA Astrophysics Data System (ADS)

Kalejs, J. P.

1994-01-01

Mobil Solar Energy Corporation currently practices a unique crystal growth technology for producing crystalline silicon sheet, which is then cut with lasers into wafers. The wafers are processed into solar cells and incorporated into modules for photovoltaic applications. The silicon sheet is produced using a method known as Edge-defined Film-fed growth (EFG), in the form of hollow eight-sided polygons (octagons) with 10 cm faces. These are grown to lengths of 5 meters and thickness of 300 microns, with continuous melt replenishment, in compact furnaces designed to operate at a high sheet area production area of 135 sq cm/min. The present Photovoltaic Manufacturing Technology (PVMaT) three-year program seeks to advance the manufacturing line capabilities of the Mobil Solar crystal growth and cutting technologies. If successful, these advancements will provide significant reductions in already low silicon raw material usage, improve process productivity, laser cutting throughput and yield, and so lower both individual wafer cost and the cost of module production. This report summarizes the significant technical improvements in EFG technology achieved in Phase 1 of this program. Technical results are reported for each of the three main program areas: (1) thin octagon growth (crystal growth) -- to reduce the thickness of the octagon to an interim goal of 250 microns during Phase 1, with an ultimate goal of achieving 200 micron thicknesses; (2) laser cutting -- to improve the laser cutting process, so as to produce wafers with decreased laser cutting damage at increased wafer throughput rates; and (3) process control and product specification -- to implement advanced strategies in crystal growth process control and productivity designed to increase wafer yields.

Alcohol Pharmacology Education Partnership: Using Chemistry and Biology Concepts To Educate High School Students about Alcohol

PubMed Central

2015-01-01

We developed the Alcohol Pharmacology Education Partnership (APEP), a set of modules designed to integrate a topic of interest (alcohol) with concepts in chemistry and biology for high school students. Chemistry and biology teachers (n = 156) were recruited nationally to field-test APEP in a controlled study. Teachers obtained professional development either at a conference-based workshop (NSTA or NCSTA) or via distance learning to learn how to incorporate the APEP modules into their teaching. They field-tested the modules in their classes during the following year. Teacher knowledge of chemistry and biology concepts increased significantly following professional development, and was maintained for at least a year. Their students (n = 14 014) demonstrated significantly higher scores when assessed for knowledge of both basic and advanced chemistry and biology concepts compared to students not using APEP modules in their classes the previous year. Higher scores were achieved as the number of modules used increased. These findings are consistent with our previous studies, demonstrating higher scores in chemistry and biology after students use modules that integrate topics interesting to them, such as drugs (the Pharmacology Education Partnership). PMID:24803686

Mathematical biology modules based on modern molecular biology and modern discrete mathematics.

PubMed

Robeva, Raina; Davies, Robin; Hodge, Terrell; Enyedi, Alexander

2010-01-01

We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-based-learning approach, the modules highlight applications of modern discrete mathematics and algebraic statistics to pressing problems in molecular biology. For the majority of projects, calculus is not a required prerequisite and, due to the modest amount of mathematical background needed for some of the modules, the materials can be used for an early introduction to mathematical modeling. At the same time, most modules are connected with topics in linear and abstract algebra, algebraic geometry, and probability, and they can be used as meaningful applied introductions into the relevant advanced-level mathematics courses. Open-source software is used to facilitate the relevant computations. As a detailed example, we outline a module that focuses on Boolean models of the lac operon network.

Mathematical Biology Modules Based on Modern Molecular Biology and Modern Discrete Mathematics

PubMed Central

Davies, Robin; Hodge, Terrell; Enyedi, Alexander

2010-01-01

We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-based-learning approach, the modules highlight applications of modern discrete mathematics and algebraic statistics to pressing problems in molecular biology. For the majority of projects, calculus is not a required prerequisite and, due to the modest amount of mathematical background needed for some of the modules, the materials can be used for an early introduction to mathematical modeling. At the same time, most modules are connected with topics in linear and abstract algebra, algebraic geometry, and probability, and they can be used as meaningful applied introductions into the relevant advanced-level mathematics courses. Open-source software is used to facilitate the relevant computations. As a detailed example, we outline a module that focuses on Boolean models of the lac operon network. PMID:20810955

A Multidisciplinary Self-Directed Learning Module Improves Knowledge of a Quality Improvement Instrument: The HEART Pathway.

PubMed

Hartman, Nicholas D; Harper, Erin N; Leppert, Lauren M; Browning, Brittany M; Askew, Kim; Manthey, David E; Mahler, Simon A

We created and tested an educational intervention to support implementation of an institution wide QI project (the HEART Pathway) designed to improve care for patients with acute chest pain. Although online learning modules have been shown effective in imparting knowledge regarding QI projects, it is unknown whether these modules are effective across specialties and healthcare professions. Participants, including nurses, advanced practice clinicians, house staff and attending physicians (N = 486), were enrolled into an online, self-directed learning course exploring the key concepts of the HEART Pathway. The module was completed by 97% of enrollees (469/486) and 90% passed on the first attempt (422/469). Out of 469 learners, 323 completed the pretest, learning module and posttest in the correct order. Mean test scores across learners improved significantly from 74% to 89% from the pretest to the posttest. Following the intervention, the HEART Pathway was used for 88% of patients presenting to our institution with acute chest pain. Our data demonstrate that this online, self-directed learning module can improve knowledge of the HEART Pathway across specialties-paving the way for more efficient and informed care for acute chest pain patients.

Advanced Structural Optimization Under Consideration of Cost Tracking

NASA Astrophysics Data System (ADS)

Zell, D.; Link, T.; Bickelmaier, S.; Albinger, J.; Weikert, S.; Cremaschi, F.; Wiegand, A.

2014-06-01

In order to improve the design process of launcher configurations in the early development phase, the software Multidisciplinary Optimization (MDO) was developed. The tool combines different efficient software tools such as Optimal Design Investigations (ODIN) for structural optimizations, Aerospace Trajectory Optimization Software (ASTOS) for trajectory and vehicle design optimization for a defined payload and mission.The present paper focuses to the integration and validation of ODIN. ODIN enables the user to optimize typical axis-symmetric structures by means of sizing the stiffening designs concerning strength and stability while minimizing the structural mass. In addition a fully automatic finite element model (FEM) generator module creates ready-to-run FEM models of a complete stage or launcher assembly.Cost tracking respectively future improvements concerning cost optimization are indicated.

Student-Centered Modules to Support Active Learning in Hydrology: Development Experiences and Users' Perspectives

NASA Astrophysics Data System (ADS)

Tarboton, D. G.; Habib, E. H.; Deshotel, M.; Merck, M. F.; Lall, U.; Farnham, D. J.

2016-12-01

Traditional approaches to undergraduate hydrology and water resource education are textbook based, adopt unit processes and rely on idealized examples of specific applications, rather than examining the contextual relations in the processes and the dynamics connecting climate and ecosystems. The overarching goal of this project is to address the needed paradigm shift in undergraduate education of engineering hydrology and water resources education to reflect parallel advances in hydrologic research and technology, mainly in the areas of new observational settings, data and modeling resources and web-based technologies. This study presents efforts to develop a set of learning modules that are case-based, data and simulation driven and delivered via a web user interface. The modules are based on real-world case studies from three regional hydrologic settings: Coastal Louisiana, Utah Rocky Mountains and Florida Everglades. These three systems provide unique learning opportunities on topics such as: regional-scale budget analysis, hydrologic effects of human and natural changes, flashflood protection, climate-hydrology teleconnections and water resource management scenarios. The technical design and contents of the modules aim to support students' ability for transforming their learning outcomes and skills to hydrologic systems other than those used by the specific activity. To promote active learning, the modules take students through a set of highly engaging learning activities that are based on analysis of hydrologic data and model simulations. The modules include user support in the form of feedback and self-assessment mechanisms that are integrated within the online modules. Module effectiveness is assessed through an improvement-focused evaluation model using a mixed-method research approach guiding collection and analysis of evaluation data. Both qualitative and quantitative data are collected through student learning data, product analysis, and staff interviews. The presentation shares with the audience lessons learned from the development and implementation of the modules, students' feedback, guidelines on design and content attributes that support active learning in hydrology, and challenges encountered during the class implementation and evaluation of the modules.

Design and Development of a Baseband Processor for the Advanced Communications Technology Satellite

NASA Technical Reports Server (NTRS)

Lee, Kerry D.

1996-01-01

This paper describes the implementation of the operational baseband processor (BBP) subsystem on board the NASA Advanced Communications Technology Satellite (ACTS). The BBP supports the network consisting of the NASA ground station (NGS) low burst rate (LBR) terminals, and the T1 very small aperture terminals (VSAT's), to provide flexible, demand assigned satellite switched (SS), baseband processed frequency division modulated (FDM)/time division multiple access (TDMA) operations. This paper presents an overview of the baseband processor and includes a description of the data flow, functional block diagrams, and a discussion of the implementation of BBP. A discussion of the supporting technologies for the BBP is presented. A brief summary of BBP-level performance testing is also presented. Finally, a discussion of the implications of current technology on the BBP design, if it were to be developed today, is presented.

Update on Development of SiC Multi-Chip Power Modules

NASA Technical Reports Server (NTRS)

Lostetter, Alexander; Cilio, Edgar; Mitchell, Gavin; Schupbach, Roberto

2008-01-01

Progress has been made in a continuing effort to develop multi-chip power modules (SiC MCPMs). This effort at an earlier stage was reported in 'SiC Multi-Chip Power Modules as Power-System Building Blocks' (LEW-18008-1), NASA Tech Briefs, Vol. 31, No. 2 (February 2007), page 28. The following recapitulation of information from the cited prior article is prerequisite to a meaningful summary of the progress made since then: 1) SiC MCPMs are, more specifically, electronic power-supply modules containing multiple silicon carbide power integrated-circuit chips and silicon-on-insulator (SOI) control integrated-circuit chips. SiC MCPMs are being developed as building blocks of advanced expandable, reconfigurable, fault-tolerant power-supply systems. Exploiting the ability of SiC semiconductor devices to operate at temperatures, breakdown voltages, and current densities significantly greater than those of conventional Si devices, the designs of SiC MCPMs and of systems comprising multiple SiC MCPMs are expected to afford a greater degree of miniaturization through stacking of modules with reduced requirements for heat sinking; 2) The stacked SiC MCPMs in a given system can be electrically connected in series, parallel, or a series/parallel combination to increase the overall power-handling capability of the system. In addition to power connections, the modules have communication connections. The SOI controllers in the modules communicate with each other as nodes of a decentralized control network, in which no single controller exerts overall command of the system. Control functions effected via the network include synchronization of switching of power devices and rapid reconfiguration of power connections to enable the power system to continue to supply power to a load in the event of failure of one of the modules; and, 3) In addition to serving as building blocks of reliable power-supply systems, SiC MCPMs could be augmented with external control circuitry to make them perform additional power-handling functions as needed for specific applications. Because identical SiC MCPM building blocks could be utilized in such a variety of ways, the cost and difficulty of designing new, highly reliable power systems would be reduced considerably. This concludes the information from the cited prior article. The main activity since the previously reported stage of development was the design, fabrication, and testing a 120- VDC-to-28-VDC modular power-converter system composed of eight SiC MCPMs in a 4 (parallel)-by-2 (series) matrix configuration, with normally-off controllable power switches. The SiC MCPM power modules include closed-loop control subsystems and are capable of operating at high power density or high temperature. The system was tested under various configurations, load conditions, load-transient conditions, and failure-recovery conditions. Planned future work includes refinement of the demonstrated modular system concept and development of a new converter hardware topology that would enable sharing of currents without the need for communication among modules. Toward these ends, it is also planned to develop a new converter control algorithm that would provide for improved sharing of current and power under all conditions, and to implement advanced packaging concepts that would enable operation at higher power density.

Performance of High Voltage Modules Under Abuse Operations

NASA Technical Reports Server (NTRS)

Jeevarajan, Judith A.; Darcy, Eric C.; Irlbeck, Bradley W.

2005-01-01

The Electric Auxiliary Power Unit (EAPU) or the Advanced Hydraulic Power System (AHPS) is a Shuttle Upgrade program. Of the two battery design approaches that were considered in support of this program, the current paper concentrates on the testing performed on the small-cell approach. Testing performed at both ComDev Space, Canada and at NASA-JSC is described in this paper. Testing included those under mission profile conditions and off-nominal abusive conditions.

Optimal packing for cascaded regenerative transmission based on phase sensitive amplifiers.

PubMed

Sorokina, Mariia; Sygletos, Stylianos; Ellis, Andrew D; Turitsyn, Sergei

2013-12-16

We investigate the transmission performance of advanced modulation formats in nonlinear regenerative channels based on cascaded phase sensitive amplifiers. We identify the impact of amplitude and phase noise dynamics along the transmission line and show that after a cascade of regenerators, densely packed single ring PSK constellations outperform multi-ring constellations. The results of this study will greatly simplify the design of future nonlinear regenerative channels for ultra-high capacity transmission.

New Advanced Technologies in Stem Cell Therapy

DTIC Science & Technology

2012-09-01

directions for this project include investigating modulation of the IKK/NF-kB pathway as a means to rejuvenate the phenotype of aged muscle stem and...Reference 1. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA. Rejuvenation of aged progenitor cells by exposure to a young...the influence that age plays on the regeneration capacity of the cells. Study Design: We will investigate the effects of cell survival, proliferation

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007417 (1 Dec. 2011) --- In the International Space Station?s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007418 (1 Dec. 2011) --- In the International Space Station’s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007419 (1 Dec. 2011) --- In the International Space Station’s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

Advanced Transport Operating System (ATOPS) utility library software description

NASA Technical Reports Server (NTRS)

Clinedinst, Winston C.; Slominski, Christopher J.; Dickson, Richard W.; Wolverton, David A.

1993-01-01

The individual software processes used in the flight computers on-board the Advanced Transport Operating System (ATOPS) aircraft have many common functional elements. A library of commonly used software modules was created for general uses among the processes. The library includes modules for mathematical computations, data formatting, system database interfacing, and condition handling. The modules available in the library and their associated calling requirements are described.

Phase-coherent engineering of electronic heat currents with a Josephson modulator

NASA Astrophysics Data System (ADS)

Fornieri, Antonio; Blanc, Christophe; Bosisio, Riccardo; D'Ambrosio, Sophie; Giazotto, Francesco

In this contribution we report the realization of the first balanced Josephson heat modulator designed to offer full control at the nanoscale over the phase-coherent component of electronic thermal currents. The ability to master the amount of heat transferred through two tunnel-coupled superconductors by tuning their phase difference is the core of coherent caloritronics, and is expected to be a key tool in a number of nanoscience fields, including solid state cooling, thermal isolation, radiation detection, quantum information and thermal logic. Our device provides magnetic-flux-dependent temperature modulations up to 40 mK in amplitude with a maximum of the flux-to-temperature transfer coefficient reaching 200 mK per flux quantum at a bath temperature of 25 mK. Foremost, it demonstrates the exact correspondence in the phase-engineering of charge and heat currents, breaking ground for advanced caloritronic nanodevices such as thermal splitters, heat pumps and time-dependent electronic engines.

Lightweight, direct-radiating nickel hydrogen batteries

NASA Technical Reports Server (NTRS)

Metcalfe, J. R.

1986-01-01

Two battery module configurations were developed which, in addition to integrating cylindrical nickel hydrogen (NiH2) cells into batteries, provide advances in the means of mounting, monitoring and thermal control of these cells. The main difference between the two modules is the physical arrangement of the cells: vertical versus horizontal. Direct thermal radiation to deep space is accomplished by substituting the battery structure for an exterior spacecraft panel. Unlike most conventional nickel-cadmium (NiCd) and NiH2 batteries, the cells are not tightly packed together; therefore ancillary heat conducting media to outside radiating areas, and spacecraft deck reinforcements for high mass concentration are not necessary. Testing included electrical characterization and a comprehensive regime of environmental exposures. The designs are flexible with respect to quantity and type of cells, orbit altitude and period, power demand profile, and the extent of cell parameter monitoring. This paper compares the characteristics of the two battery modules and summarizes their performance.

Rad-Hard, Miniaturized, Scalable, High-Voltage Switching Module for Power Applications Rad-Hard, Miniaturized

NASA Technical Reports Server (NTRS)

Adell, Philippe C.; Mojarradi, Mohammad; DelCastillo, Linda Y.; Vo, Tuan A.

2011-01-01

A paper discusses the successful development of a miniaturized radiation hardened high-voltage switching module operating at 2.5 kV suitable for space application. The high-voltage architecture was designed, fabricated, and tested using a commercial process that uses a unique combination of 0.25 micrometer CMOS (complementary metal oxide semiconductor) transistors and high-voltage lateral DMOS (diffusion metal oxide semiconductor) device with high breakdown voltage (greater than 650 V). The high-voltage requirements are achieved by stacking a number of DMOS devices within one module, while two modules can be placed in series to achieve higher voltages. Besides the high-voltage requirements, a second generation prototype is currently being developed to provide improved switching capabilities (rise time and fall time for full range of target voltages and currents), the ability to scale the output voltage to a desired value with good accuracy (few percent) up to 10 kV, to cover a wide range of high-voltage applications. In addition, to ensure miniaturization, long life, and high reliability, the assemblies will require intensive high-voltage electrostatic modeling (optimized E-field distribution throughout the module) to complete the proposed packaging approach and test the applicability of using advanced materials in a space-like environment (temperature and pressure) to help prevent potential arcing and corona due to high field regions. Finally, a single-event effect evaluation would have to be performed and single-event mitigation methods implemented at the design and system level or developed to ensure complete radiation hardness of the module.

Candidate materials for advanced fire-resistant photovoltaic modules

NASA Technical Reports Server (NTRS)

Sugimura, R. S.; Otth, D. H.; Ross, R. G., Jr.; Arnett, J. C.; Samuelson, G.

1985-01-01

A cooperative, cost-sharing research effort to develop a technology base required to construct fire-ratable photovoltaic modules has resulted in the identification of several high-temperature, back-surface candidate materials capable of raising the fire-resistance of modules using hydrocarbon encapsulants to Class A and B levels. Advanced experimental module configurations have been developed using back surfaces consisting of Kapton, Tedlar laminates, metal-foils, and fiberglass materials with high-temperature coatings. Test results (October 1984; March 1985; May 1985; and October 1985) indicate that several of these advanced module configurations are capable of achieving Class B fire-resistance levels, while a few configurations can achieve Class A levels. The paper summarizes activities to date, discussing flammability failure mechanisms, time-temperature profiles, and results of Block V environmental exposure tests of a candidate material suitable for both Class B and Class A fire-resistance levels.

Evaluation of advanced air bag deployment algorithm performance using event data recorders.

PubMed

Gabler, Hampton C; Hinch, John

2008-10-01

This paper characterizes the field performance of occupant restraint systems designed with advanced air bag features including those specified in the US Federal Motor Vehicle Safety Standard (FMVSS) No. 208 for advanced air bags, through the use of Event Data Recorders (EDRs). Although advanced restraint systems have been extensively tested in the laboratory, we are only beginning to understand the performance of these systems in the field. Because EDRs record many of the inputs to the advanced air bag control module, these devices can provide unique insights into the characteristics of field performance of air bags. The study was based on 164 advanced air bag cases extracted from NASS/CDS 2002-2006 with associated EDR data. In this dataset, advanced driver air bags were observed to deploy with a 50% probability at a longitudinal delta-V of 9 mph for the first stage, and at 26 mph for both inflator stages. In general, advanced air bag performance was as expected, however, the study identified cases of air bag deployments at delta-Vs as low as 3-4 mph, non-deployments at delta-Vs over 26 mph, and possible delayed air bag deployments.

Evaluation of Advanced Air Bag Deployment Algorithm Performance using Event Data Recorders

PubMed Central

Gabler, Hampton C.; Hinch, John

2008-01-01

This paper characterizes the field performance of occupant restraint systems designed with advanced air bag features including those specified in the US Federal Motor Vehicle Safety Standard (FMVSS) No. 208 for advanced air bags, through the use of Event Data Recorders (EDRs). Although advanced restraint systems have been extensively tested in the laboratory, we are only beginning to understand the performance of these systems in the field. Because EDRs record many of the inputs to the advanced air bag control module, these devices can provide unique insights into the characteristics of field performance of air bags. The study was based on 164 advanced air bag cases extracted from NASS/CDS 2002-2006 with associated EDR data. In this dataset, advanced driver air bags were observed to deploy with a 50% probability at a longitudinal delta-V of 9 mph for the first stage, and at 26 mph for both inflator stages. In general, advanced air bag performance was as expected, however, the study identified cases of air bag deployments at delta-Vs as low as 3-4 mph, non-deployments at delta-Vs over 26 mph, and possible delayed air bag deployments. PMID:19026234

Development of a High Fidelity Dynamic Module of the Advanced Resistive Exercise Device (ARED) Using Adams

NASA Technical Reports Server (NTRS)

Humphreys, B. T.; Thompson, W. K.; Lewandowski, B. E.; Cadwell, E. E.; Newby, N. J.; Fincke, R. S.; Sheehan, C.; Mulugeta, L.

2012-01-01

NASA's Digital Astronaut Project (DAP) implements well-vetted computational models to predict and assess spaceflight health and performance risks, and enhance countermeasure development. DAP provides expertise and computation tools to its research customers for model development, integration, or analysis. DAP is currently supporting the NASA Exercise Physiology and Countermeasures (ExPC) project by integrating their biomechanical models of specific exercise movements with dynamic models of the devices on which the exercises were performed. This presentation focuses on the development of a high fidelity dynamic module of the Advanced Resistive Exercise Device (ARED) on board the ISS. The ARED module, illustrated in the figure below, was developed using the Adams (MSC Santa Ana, California) simulation package. The Adams package provides the capabilities to perform multi rigid body, flexible body, and mixed dynamic analyses of complex mechanisms. These capabilities were applied to accurately simulate: Inertial and mass properties of the device such as the vibration isolation system (VIS) effects and other ARED components, Non-linear joint friction effects, The gas law dynamics of the vacuum cylinders and VIS components using custom written differential state equations, The ARED flywheel dynamics, including torque limiting clutch. Design data from the JSC ARED Engineering team was utilized in developing the model. This included solid modeling geometry files, component/system specifications, engineering reports and available data sets. The Adams ARED module is importable into LifeMOD (Life Modeler, Inc., San Clemente, CA) for biomechanical analyses of different resistive exercises such as squat and dead-lift. Using motion capture data from ground test subjects, the ExPC developed biomechanical exercise models in LifeMOD. The Adams ARED device module was then integrated with the exercise subject model into one integrated dynamic model. This presentation will describe the development of the Adams ARED module including its capabilities, limitations, and assumptions. Preliminary results, validation activities, and a practical application of the module to inform the relative effect of the flywheels on exercise will be discussed.

Designing high-quality interactive multimedia learning modules.

PubMed

Huang, Camillan

2005-01-01

Modern research has broadened scientific knowledge and revealed the interdisciplinary nature of the sciences. For today's students, this advance translates to learning a more diverse range of concepts, usually in less time, and without supporting resources. Students can benefit from technology-enhanced learning supplements that unify concepts and are delivered on-demand over the Internet. Such supplements, like imaging informatics databases, serve as innovative references for biomedical information, but could improve their interaction interfaces to support learning. With information from these digital datasets, multimedia learning tools can be designed to transform learning into an active process where students can visualize relationships over time, interact with dynamic content, and immediately test their knowledge. This approach bridges knowledge gaps, fosters conceptual understanding, and builds problem-solving and critical thinking skills-all essential components to informatics training for science and medicine. Additional benefits include cost-free access and ease of dissemination over the Internet or CD-ROM. However, current methods for the design of multimedia learning modules are not standardized and lack strong instructional design. Pressure from administrators at the top and students from the bottom are pushing faculty to use modern technology to address the learning needs and expectations of contemporary students. Yet, faculty lack adequate support and training to adopt this new approach. So how can faculty learn to create educational multimedia materials for their students? This paper provides guidelines on best practices in educational multimedia design, derived from the Virtual Labs Project at Stanford University. The development of a multimedia module consists of five phases: (1) understand the learning problem and the users needs; (2) design the content to harness the enabling technologies; (3) build multimedia materials with web style standards and human factors principles; (4) user testing; (5) evaluate and improve design.

CHARMM-GUI PDB manipulator for advanced modeling and simulations of proteins containing nonstandard residues.

PubMed

Jo, Sunhwan; Cheng, Xi; Islam, Shahidul M; Huang, Lei; Rui, Huan; Zhu, Allen; Lee, Hui Sun; Qi, Yifei; Han, Wei; Vanommeslaeghe, Kenno; MacKerell, Alexander D; Roux, Benoît; Im, Wonpil

2014-01-01

CHARMM-GUI, http://www.charmm-gui.org, is a web-based graphical user interface to prepare molecular simulation systems and input files to facilitate the usage of common and advanced simulation techniques. Since it is originally developed in 2006, CHARMM-GUI has been widely adopted for various purposes and now contains a number of different modules designed to setup a broad range of simulations including free energy calculation and large-scale coarse-grained representation. Here, we describe functionalities that have recently been integrated into CHARMM-GUI PDB Manipulator, such as ligand force field generation, incorporation of methanethiosulfonate spin labels and chemical modifiers, and substitution of amino acids with unnatural amino acids. These new features are expected to be useful in advanced biomolecular modeling and simulation of proteins. © 2014 Elsevier Inc. All rights reserved.

Advanced Packaging Materials and Techniques for High Power TR Module: Standard Flight vs. Advanced Packaging

NASA Technical Reports Server (NTRS)

Hoffman, James Patrick; Del Castillo, Linda; Miller, Jennifer; Jenabi, Masud; Hunter, Donald; Birur, Gajanana

2011-01-01

The higher output power densities required of modern radar architectures, such as the proposed DESDynI [Deformation, Ecosystem Structure, and Dynamics of Ice] SAR [Synthetic Aperture Radar] Instrument (or DSI) require increasingly dense high power electronics. To enable these higher power densities, while maintaining or even improving hardware reliability, requires advances in integrating advanced thermal packaging technologies into radar transmit/receive (TR) modules. New materials and techniques have been studied and compared to standard technologies.

Surface Acoustic Wave Vibration Sensors for Measuring Aircraft Flutter

NASA Technical Reports Server (NTRS)

Wilson, William C.; Moore, Jason P.; Juarez, Peter D.

2016-01-01

Under NASA's Advanced Air Vehicles Program the Advanced Air Transport Technology (AATT) Project is investigating flutter effects on aeroelastic wings. To support that work a new method for measuring vibrations due to flutter has been developed. The method employs low power Surface Acoustic Wave (SAW) sensors. To demonstrate the ability of the SAW sensor to detect flutter vibrations the sensors were attached to a Carbon fiber-reinforced polymer (CFRP) composite panel which was vibrated at six frequencies from 1Hz to 50Hz. The SAW data was compared to accelerometer data and was found to resemble sine waves and match each other closely. The SAW module design and results from the tests are presented here.

Assessment of a new undergraduate module in musculoskeletal medicine.

PubMed

Queally, Joseph M; Cummins, Fionnan; Brennan, Stephen A; Shelly, Martin J; O'Byrne, John M

2011-02-02

Despite the high prevalence of musculoskeletal disorders seen by primary care physicians, numerous studies have demonstrated deficiencies in the adequacy of musculoskeletal education at multiple stages of medical education. The aim of this study was to assess a newly developed module in musculoskeletal medicine for use at European undergraduate level (i.e., the medical-school level). A two-week module in musculoskeletal medicine was designed to cover common musculoskeletal disorders that are typically seen in primary care. The module incorporated an integrated approach, including core lectures, bedside clinical examination, and demonstration of basic practical procedures. A previously validated examination in musculoskeletal medicine was used to assess the cognitive knowledge of ninety-two students on completion of the module. A historical control group (seventy-two students) from a prior course was used for comparison. The new module group (2009) performed significantly better than the historical (2006) control group in terms of score (62.3% versus 54.3%, respectively; p < 0.001) and pass rate (38.4% versus 12.5%, respectively; p = 0.0002). In a subgroup analysis of the new module group, students who enrolled in the graduate entry program (an accelerated four-year curriculum consisting of students who have already completed an undergraduate university degree) were more likely to perform better in terms of average score (72.2% versus 57%, respectively; p < 0.001) and pass rates (70.9% versus 21.4%, respectively; p < 0.001) compared with students who had enrolled via the traditional undergraduate route. In terms of satisfaction rates, the new module group reported a significantly higher satisfaction rate than that reported by the historical control group (63% versus 15%, respectively; p < 0.001). In conclusion, the musculoskeletal module described in this paper represents an educational advance at undergraduate (i.e., medical-school) level as demonstrated by the improvement in scores in a validated examination. As pressure on medical curricula grows to accommodate advancing medical knowledge, it is important to continue to improve, assess, and consolidate the position of musculoskeletal medicine in contemporary medical education.

Current pain education within undergraduate medical studies across Europe: Advancing the Provision of Pain Education and Learning (APPEAL) study.

PubMed

Briggs, Emma V; Battelli, Daniele; Gordon, David; Kopf, Andreas; Ribeiro, Sofia; Puig, Margarita M; Kress, Hans G

2015-08-10

Unrelieved pain is a substantial public health concern necessitating improvements in medical education. The Advancing the Provision of Pain Education and Learning (APPEAL) study aimed to determine current levels and methods of undergraduate pain medicine education in Europe. Using a cross-sectional design, publicly available curriculum information was sought from all medical schools in 15 representative European countries in 2012-2013. Descriptive analyses were performed on: the provision of pain teaching in dedicated pain modules, other modules or within the broader curriculum; whether pain teaching was compulsory or elective; the number of hours/credits spent teaching pain; pain topics; and teaching and assessment methods. Curriculum elements were publicly available from 242 of 249 identified schools (97%). In 55% (133/242) of schools, pain was taught only within compulsory non-pain-specific modules. The next most common approaches were for pain teaching to be provided wholly or in part via a dedicated pain module (74/242; 31%) or via a vertical or integrated approach to teaching through the broader curriculum, rather than within any specific module (17/242; 7%). The curricula of 17/242 schools (7%) showed no evidence of any pain teaching. Dedicated pain modules were most common in France (27/31 schools; 87%). Excluding France, only 22% (47/211 schools) provided a dedicated pain module and in only 9% (18/211) was this compulsory. Overall, the median number of hours spent teaching pain was 12.0 (range 4-56.0 h; IQR: 12.0) for compulsory dedicated pain modules and 9.0 (range 1.0-60.0 h; IQR: 10.5) for other compulsory (non-pain specific) modules. Pain medicine was principally taught in classrooms and assessed by conventional examinations. There was substantial international variation throughout. Documented pain teaching in many European medical schools falls far short of what might be expected given the prevalence and public health burden of pain. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Can 100Gb/s wavelengths be deployed using 10Gb/s engineering rules?

NASA Astrophysics Data System (ADS)

Saunders, Ross; Nicholl, Gary; Wollenweber, Kevin; Schmidt, Ted

2007-09-01

A key challenge set by carriers for 40Gb/s deployments was that the 40Gb/s wavelengths should be deployable over existing 10Gb/s DWDM systems, using 10Gb/s link engineering design rules. Typical 10Gb/s link engineering rules are: 1. Polarization Mode Dispersion (PMD) tolerance of 10ps (mean); 2. Chromatic Dispersion (CD) tolerance of +/-700ps/nm 3. Operation at 50GHz channel spacing, including transit through multiple cascaded [R]OADMs; 4. Optical reach up to 2,000km. By using a combination of advanced modulation formats and adaptive dispersion compensation (technologies rarely seen at 10Gb/s outside of the submarine systems space), vendors did respond to the challenge and broadly met this requirement. As we now start to explore feasible technologies for 100Gb/s optical transport, driven by 100GE port availability on core IP routers, the carrier challenge remains the same. 100Gb/s links should be deployable over existing 10Gb/s DWDM systems using 10Gb/s link engineering rules (as listed above). To meet this challenge, optical transport technology must evolve to yet another level of complexity/maturity in both modulation formats and adaptive compensation techniques. Many clues as to how this might be achieved can be gained by first studying sister telecommunications industries, e.g. satellite (QPSK, QAM, LDCP FEC codes), wireless (advanced DSP, MSK), HDTV (TCM), etc. The optical industry is not a pioneer of new ideas in modulation schemes and coding theory, we will always be followers. However, we do have the responsibility of developing the highest capacity "modems" on the planet to carry the core backbone traffic of the Internet. As such, the key to our success will be to analyze the pros and cons of advanced modulation/coding techniques and balance this with the practical limitations of high speed electronics processing speed and the challenges of real world optical layer impairments. This invited paper will present a view on what advanced technologies are likely candidates to support 100GE optical IP transport over existing 10Gb/s DWDM systems, using 10Gb/s link engineering rules.

Performance of the NEXT Engineering Model Power Processing Unit

NASA Technical Reports Server (NTRS)

Pinero, Luis R.; Hopson, Mark; Todd, Philip C.; Wong, Brian

2007-01-01

The NASA s Evolutionary Xenon Thruster (NEXT) project is developing an advanced ion propulsion system for future NASA missions for solar system exploration. An engineering model (EM) power processing unit (PPU) for the NEXT project was designed and fabricated by L-3 Communications under contract with NASA Glenn Research Center (GRC). This modular PPU is capable of processing up from 0.5 to 7.0 kW of output power for the NEXT ion thruster. Its design includes many significant improvements for better performance over the state-of-the-art PPU. The most significant difference is the beam supply which is comprised of six modules and capable of very efficient operation through a wide voltage range because of innovative features like dual controls, module addressing, and a high current mode. The low voltage power supplies are based on elements of the previously validated NASA Solar Electric Propulsion Technology Application Readiness (NSTAR) PPU. The highly modular construction of the PPU resulted in improved manufacturability, simpler scalability, and lower cost. This paper describes the design of the EM PPU and the results of the bench-top performance tests.

Land Mobile Satellite Service (LMSS) channel simulator: An end-to-end hardware simulation and study of the LMSS communications links

NASA Technical Reports Server (NTRS)

Salmasi, A. B. (Editor); Springett, J. C.; Sumida, J. T.; Richter, P. H.

1984-01-01

The design and implementation of the Land Mobile Satellite Service (LMSS) channel simulator as a facility for an end to end hardware simulation of the LMSS communications links, primarily with the mobile terminal is described. A number of studies are reported which show the applications of the channel simulator as a facility for validation and assessment of the LMSS design requirements and capabilities by performing quantitative measurements and qualitative audio evaluations for various link design parameters and channel impairments under simulated LMSS operating conditions. As a first application, the LMSS channel simulator was used in the evaluation of a system based on the voice processing and modulation (e.g., NBFM with 30 kHz of channel spacing and a 2 kHz rms frequency deviation for average talkers) selected for the Bell System's Advanced Mobile Phone Service (AMPS). The various details of the hardware design, qualitative audio evaluation techniques, signal to channel impairment measurement techniques, the justifications for criteria of different parameter selection in regards to the voice processing and modulation methods, and the results of a number of parametric studies are further described.

The Fresenius Medical Care home hemodialysis system.

PubMed

Schlaeper, Christian; Diaz-Buxo, Jose A

2004-01-01

The Fresenius Medical Care home dialysis system consists of a newly designed machine, a central monitoring system, a state-of-the-art reverse osmosis module, ultrapure water, and all the services associated with a successful implementation. The 2008K@home hemodialysis machine has the flexibility to accommodate the changing needs of the home hemodialysis patient and is well suited to deliver short daily or prolonged nocturnal dialysis using a broad range of dialysate flows and concentrates. The intuitive design, large graphic illustrations, and step-by-step tutorial make this equipment very user friendly. Patient safety is assured by the use of hydraulic systems with a long history of reliability, smart alarm algorithms, and advanced electronic monitoring. To further patient comfort with their safety at home, the 2008K@home is enabled to communicate with the newly designed iCare remote monitoring system. The Aquaboss Smart reverse osmosis (RO) system is compact, quiet, highly efficient, and offers an improved hygienic design. The RO module reduces water consumption by monitoring the water flow of the dialysis system and adjusting water production accordingly. The Diasafe Plus filter provides ultrapure water, known for its long-term benefits. This comprehensive approach includes planning, installation, technical and clinical support, and customer service.

Deep learning with convolutional neural networks for EEG decoding and visualization

PubMed Central

Springenberg, Jost Tobias; Fiederer, Lukas Dominique Josef; Glasstetter, Martin; Eggensperger, Katharina; Tangermann, Michael; Hutter, Frank; Burgard, Wolfram; Ball, Tonio

2017-01-01

Abstract Deep learning with convolutional neural networks (deep ConvNets) has revolutionized computer vision through end‐to‐end learning, that is, learning from the raw data. There is increasing interest in using deep ConvNets for end‐to‐end EEG analysis, but a better understanding of how to design and train ConvNets for end‐to‐end EEG decoding and how to visualize the informative EEG features the ConvNets learn is still needed. Here, we studied deep ConvNets with a range of different architectures, designed for decoding imagined or executed tasks from raw EEG. Our results show that recent advances from the machine learning field, including batch normalization and exponential linear units, together with a cropped training strategy, boosted the deep ConvNets decoding performance, reaching at least as good performance as the widely used filter bank common spatial patterns (FBCSP) algorithm (mean decoding accuracies 82.1% FBCSP, 84.0% deep ConvNets). While FBCSP is designed to use spectral power modulations, the features used by ConvNets are not fixed a priori. Our novel methods for visualizing the learned features demonstrated that ConvNets indeed learned to use spectral power modulations in the alpha, beta, and high gamma frequencies, and proved useful for spatially mapping the learned features by revealing the topography of the causal contributions of features in different frequency bands to the decoding decision. Our study thus shows how to design and train ConvNets to decode task‐related information from the raw EEG without handcrafted features and highlights the potential of deep ConvNets combined with advanced visualization techniques for EEG‐based brain mapping. Hum Brain Mapp 38:5391–5420, 2017. © 2017 Wiley Periodicals, Inc. PMID:28782865

Deep learning with convolutional neural networks for EEG decoding and visualization.

PubMed

Schirrmeister, Robin Tibor; Springenberg, Jost Tobias; Fiederer, Lukas Dominique Josef; Glasstetter, Martin; Eggensperger, Katharina; Tangermann, Michael; Hutter, Frank; Burgard, Wolfram; Ball, Tonio

2017-11-01

Deep learning with convolutional neural networks (deep ConvNets) has revolutionized computer vision through end-to-end learning, that is, learning from the raw data. There is increasing interest in using deep ConvNets for end-to-end EEG analysis, but a better understanding of how to design and train ConvNets for end-to-end EEG decoding and how to visualize the informative EEG features the ConvNets learn is still needed. Here, we studied deep ConvNets with a range of different architectures, designed for decoding imagined or executed tasks from raw EEG. Our results show that recent advances from the machine learning field, including batch normalization and exponential linear units, together with a cropped training strategy, boosted the deep ConvNets decoding performance, reaching at least as good performance as the widely used filter bank common spatial patterns (FBCSP) algorithm (mean decoding accuracies 82.1% FBCSP, 84.0% deep ConvNets). While FBCSP is designed to use spectral power modulations, the features used by ConvNets are not fixed a priori. Our novel methods for visualizing the learned features demonstrated that ConvNets indeed learned to use spectral power modulations in the alpha, beta, and high gamma frequencies, and proved useful for spatially mapping the learned features by revealing the topography of the causal contributions of features in different frequency bands to the decoding decision. Our study thus shows how to design and train ConvNets to decode task-related information from the raw EEG without handcrafted features and highlights the potential of deep ConvNets combined with advanced visualization techniques for EEG-based brain mapping. Hum Brain Mapp 38:5391-5420, 2017. © 2017 Wiley Periodicals, Inc. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

Earth System Science Education for the 21st Century: Progress and Plans

NASA Astrophysics Data System (ADS)

Ruzek, M.; Johnson, D. R.; Wake, C.; Aron, J.

2005-12-01

Earth System Science Education for the 21st Century (ESSE 21) is a collaborative undergraduate/graduate Earth system science education program sponsored by NASA offering small grants to colleges and universities with special emphasis on including minority institutions to engage faculty and scientists in the development of Earth system science courses, curricula, degree programs and shared learning resources. The annual ESSE 21 meeting in Fairbanks in August, 2005 provided an opportunity for 70 undergraduate educators and scientists to share their best classroom learning resources through a series of short presentations, posters and skills workshops. This poster will highlight meeting results, advances in the development of ESS learning modules, and describe a community-led proposal to develop in the coming year a Design Guide for Undergraduate Earth system Science Education to be based upon the experience of the 63 NASA-supported ESSE teams over the past 15 years. As a living document on the Web, the Design Guide would utilize and share ESSE experiences that: - Advance understanding of the Earth as a system - Apply ESS to the Vision for Space Exploration - Create environments appropriate for teaching and learning ESS - Improve STEM literacy and broaden career paths - Transform institutional priorities and approaches to ESS - Embrace ESS within Minority Serving Institutions - Build collaborative interdisciplinary partnerships - Develop ESS learning resources and modules The Design Guide aims to be a synthesis of just how ESS has been and is being implemented in the college and university environment, listing items essential for undergraduate Earth system education that reflect the collective wisdom of the ESS education community. The Design Guide will focus the vision for ESS in the coming decades, define the challenges, and explore collaborative processes that utilize the next generation of information and communication technology.

Advancements in n-Type Base Crystalline Silicon Solar Cells and Their Emergence in the Photovoltaic Industry

PubMed Central

ur Rehman, Atteq; Lee, Soo Hong

2013-01-01

The p-type crystalline silicon wafers have occupied most of the solar cell market today. However, modules made with n-type crystalline silicon wafers are actually the most efficient modules up to date. This is because the material properties offered by n-type crystalline silicon substrates are suitable for higher efficiencies. Properties such as the absence of boron-oxygen related defects and a greater tolerance to key metal impurities by n-type crystalline silicon substrates are major factors that underline the efficiency of n-type crystalline silicon wafer modules. The bi-facial design of n-type cells with good rear-side electronic and optical properties on an industrial scale can be shaped as well. Furthermore, the development in the industrialization of solar cell designs based on n-type crystalline silicon substrates also highlights its boost in the contributions to the photovoltaic industry. In this paper, a review of various solar cell structures that can be realized on n-type crystalline silicon substrates will be given. Moreover, the current standing of solar cell technology based on n-type substrates and its contribution in photovoltaic industry will also be discussed. PMID:24459433

Advancements in n-type base crystalline silicon solar cells and their emergence in the photovoltaic industry.

PubMed

ur Rehman, Atteq; Lee, Soo Hong

2013-01-01

The p-type crystalline silicon wafers have occupied most of the solar cell market today. However, modules made with n-type crystalline silicon wafers are actually the most efficient modules up to date. This is because the material properties offered by n-type crystalline silicon substrates are suitable for higher efficiencies. Properties such as the absence of boron-oxygen related defects and a greater tolerance to key metal impurities by n-type crystalline silicon substrates are major factors that underline the efficiency of n-type crystalline silicon wafer modules. The bi-facial design of n-type cells with good rear-side electronic and optical properties on an industrial scale can be shaped as well. Furthermore, the development in the industrialization of solar cell designs based on n-type crystalline silicon substrates also highlights its boost in the contributions to the photovoltaic industry. In this paper, a review of various solar cell structures that can be realized on n-type crystalline silicon substrates will be given. Moreover, the current standing of solar cell technology based on n-type substrates and its contribution in photovoltaic industry will also be discussed.

Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future Therapeutics.

PubMed

Remesic, Michael; Hruby, Victor J; Porreca, Frank; Lee, Yeon Sun

2017-06-21

Opioids, and more specifically μ-opioid receptor (MOR) agonists such as morphine, have long been clinically used as therapeutics for severe pain states but often come with serious side effects such as addiction and tolerance. Many studies have focused on bringing about analgesia from the MOR with attenuated side effects, but its underlying mechanism is not fully understood. Recently, focus has been geared toward the design and elucidation of the orthosteric site with ligands of various biological profiles and mixed subtype opioid activities and selectivities, but targeting the allosteric site is an area of increasing interest. It has been shown that allosteric modulators play key roles in influencing receptor function such as its tolerance to a ligand and affect downstream pathways. There has been a high variance of chemical structures that provide allosteric modulation at a given receptor, but recent studies and reviews tend to focus on the altered cellular mechanisms instead of providing a more rigorous description of the allosteric ligand's structure-function relationship. In this review, we aim to explore recent developments in the structural motifs that potentiate orthosteric binding and their influences on cellular pathways in an effort to present novel approaches to opioid therapeutic design.

Using health communication best practices to develop a web-based provider-patient communication aid: the CONNECT study.

PubMed

Fleisher, Linda; Buzaglo, Joanne; Collins, Michael; Millard, Jennifer; Miller, Suzanne M; Egleston, Brian L; Solarino, Nicholas; Trinastic, Jonathan; Cegala, Donald J; Benson, Al B; Schulman, Kevin A; Weinfurt, Kevin P; Sulmasy, Daniel; Diefenbach, Michael A; Meropol, Neal J

2008-06-01

Although there is broad consensus that careful content vetting and user testing is important in the development of technology-based educational interventions, often these steps are overlooked. This paper highlights the development of a theory-guided, web-based communication aid (CONNECT), designed to facilitate treatment decision-making among patients with advanced cancer. The communication aid included an on-line survey, patient skills training module and an automated physician report. Development steps included: (1) evidence-based content development; (2) usability testing; (3) pilot testing; and (4) patient utilization and satisfaction. Usability testing identified some confusing directions and navigation for the on-line survey and validated the relevance of the "patient testimonials" in the skills module. Preliminary satisfaction from the implementation of the communication aid showed that 66% found the survey length reasonable and 70% found it helpful in talking with the physician. Seventy percent reported the skills module helpful and about half found it affected the consultation. Designing patient education interventions for translation into practice requires the integration of health communication best practice including user feedback along the developmental process. This developmental process can be translated to a broad array of community-based patient and provider educational interventions.

Using Advances in Research on Louisiana Coastal Restoration and Protection to Develop Undergraduate Hydrology Education Experiences Delivered via a Web Interface

NASA Astrophysics Data System (ADS)

Bodin, M.; Habib, E. H.; Meselhe, E. A.; Visser, J.; Chimmula, S.

2014-12-01

Utilizing advances in hydrologic research and technology, learning modules can be developed to deliver visual, case-based, data and simulation driven educational experiences. This paper focuses on the development of web modules based on case studies in Coastal Louisiana, one of three ecosystems that comprise an ongoing hydrology education online system called HydroViz. The Chenier Plain ecosystem in Coastal Louisiana provides an abundance of concepts and scenarios appropriate for use in many undergraduate water resource and hydrology curricula. The modules rely on a set of hydrologic data collected within the Chenier Plain along with inputs and outputs of eco-hydrology and vegetation-change simulation models that were developed to analyze different restoration and protection projects within the 2012 Louisiana Costal Master Plan. The modules begin by investigating the basic features of the basin and it hydrologic characteristics. The eco-hydrology model is then introduced along with its governing equations, numerical solution scheme and how it represents the study domain. Concepts on water budget in a coastal basin are then introduced using the simulation model inputs, outputs and boundary conditions. The complex relationships between salinity, water level and vegetation changes are then investigated through the use of the simulation models and associated field data. Other student activities focus on using the simulation models to evaluate tradeoffs and impacts of actual restoration and protection projects that were proposed as part of 2012 Louisiana Master Plan. The hands-on learning activities stimulate student learning of hydrologic and water management concepts by providing real-world context and opportunity to build fundamental knowledge as well as practical skills. The modules are delivered through a carefully designed user interface using open source and free technologies which enable wide dissemination and encourage adaptation by others.

STS-55 German Payload Specialist Schlegel manipulates ROTEX controls in SL-D2

NASA Image and Video Library

1993-05-06

STS055-106-100 (26 April-6 May 1993) --- Hans Schlegel, wearing special glasses, works at the Robotics Experiment (ROTEX) workstation in the science module aboard the Earth-orbiting Space Shuttle Columbia. Schlegel was one of two payload specialists representing the German Aerospace Research Establishment (DLR) on the 10-day Spacelab D-2 mission. ROTEX is a robotic arm that operates within an enclosed workcell in rack 6 of the Spacelab module and uses teleoperation from both an onboard station located nearby in rack 4 and from a station on the ground. The device uses teleprogramming and artificial intelligence to look at the design, verification and operation of advanced autonomous systems for use in future applications.

Size and Electronic Modulation of Iridium Nanoparticles on Nitrogen Functionalized Carbon toward Advanced Electrocatalysts for Alkaline Water Splitting.

PubMed

Wang, Hua; Ming, Mei; Hu, Min; Xu, Caili; Wang, Yi; Zhang, Yun; Gao, Daojiang; Bi, Jian; Fan, Guangyin; Hu, Jin-Song

2018-06-14

Developing efficient catalytic materials for electrochemical water splitting is important. Herein, uniformly dispersed and size-controllable iridium (Ir) nanoparticles (NPs) were prepared using a nitrogen-functionalized carbon (Ir/CN) as the support. We found that nitrogen function can simultaneously modulate the size of Ir NPs to substantially enhance the catalytically active sites and adjust the electronic structure of Ir, thereby promoting electrocatalytic activity for water splitting. Consequently, the as-synthesized Ir/CN shows excellent electrocatalytic performance with overpotentials of 12 and 265 mV for hydrogen and oxygen evolution reactions in basic medium, respectively. These findings may pave a way for designing and synthesizing other similar materials as efficient catalysts for electrochemical water splitting.

On acquiring decision making skills for endovascular interventions.

PubMed

Lanzer, Peter; Prechelt, Lutz

2008-11-01

To improve interventional training we propose a staged rational approach for decision making and skill acquisition. Education and training for endovascular interventions should start to develop the learners' decision-making skills by learning from explicit representations of master interventionist's tacit decision-making knowledge through implementation of the notions of generic interventional modules, interventional strategic and tactical designs. We hope that these suggestions will encourage action, stimulate dialogue and advance the precision of our learning, procedures, practice and patient care.

50Gb/s PAM-4 oxide VCSEL development progress at Broadcom

NASA Astrophysics Data System (ADS)

Wang, Jingyi; Murty, M. V. Ramana; Wang, Charlie; Hui, David; Lehman Harren, Ann; Chang, Hsu-Hao; Feng, Zheng-Wen; Fanning, Thomas R.; Sridhara, Aaditya; Taslim, Sumitro-Joyo; Cai, Xinle; Chu, Jason; Giovane, Laura M.

2017-02-01

This paper will review the device design and performance of Broadcom's 50Gb/s PAM-4 VCSEL to enable the next generation of transceivers using a PAM-4 advanced modulation scheme at 25-28 GBd. The VCSEL has been optimized to minimize noise and improve dynamic performance for cleaner eyes. Preliminary wear out lifetime studies indicate that the time to 1% failure exceeds 10 years, making the VCSELs suitable for data communication applications.

Spectral efficiency in crosstalk-impaired multi-core fiber links

NASA Astrophysics Data System (ADS)

Luís, Ruben S.; Puttnam, Benjamin J.; Rademacher, Georg; Klaus, Werner; Agrell, Erik; Awaji, Yoshinari; Wada, Naoya

2018-02-01

We review the latest advances on ultra-high throughput transmission using crosstalk-limited single-mode multicore fibers and compare these with the theoretical spectral efficiency of such systems. We relate the crosstalkimposed spectral efficiency limits with fiber parameters, such as core diameter, core pitch, and trench design. Furthermore, we investigate the potential of techniques such as direction interleaving and high-order MIMO to improve the throughput or reach of these systems when using various modulation formats.

Design of an Advanced Modular Automated Evaluation System for Experimental High Power SGTOS

DTIC Science & Technology

2013-06-01

POWER SGTOS Shelby Lacouture, Kevin Lawson, Stephen Bayne, Michael Giesselmann, Heather O’Brien 1 , Aderinto Ogunniyi 1 , Charles J...Travis T. Vollmer and Michael G. Giesselmann, Rapid Capacitor Charging Power Supply for an 1800J PFN, Proceedings of the 2012 Power Modulator and High Voltage Conference, San Diego, CA, June 3-7, 2012. 1023 ...Scozzie 1 Center for Pulsed Power and Power Electronics Department of Electrical & Computer Engineering Texas Tech

Sodium Variable Conductance Heat Pipe for Radioisotope Stirling Systems

NASA Technical Reports Server (NTRS)

Tarau, Calin; Anderson, William G.; Walker, Kara

2009-01-01

In a Stirling radioisotope system, heat must continually be removed from the General Purpose Heat Source (GPHS) modules to maintain the modules and surrounding insulation at acceptable temperatures. Normally, the Stirling convertor provides this cooling. If the converter stops in the current system, the insulation is designed to spoil, preventing damage to the GPHS, and also ending the mission. An alkali-metal Variable Conductance Heat Pipe (VCHP) has been designed to allow multiple stops and restarts of the Stirling convertor in an Advanced Stirling Radioisotope Generator (ASRG). When the Stirling convertor is turned off, the VCHP will activate when the temperatures rises 30 C above the setpoint temperature. A prototype VCHP with sodium as the working fluid was fabricated and tested in both gravity aided and against gravity conditions for a nominal heater head temperature of 790 C. The results show very good agreement with the predictions and validate the model. The gas front was located at the exit of the reservoir when heater head temperature was 790 C while cooling was ON, simulating an operating Advanced Stirling Converter (ASC). When cooling stopped, the temperature increased by 30 C, allowing the gas front to move past the radiator, which transferred the heat to the case. After resuming the cooling flow, the front returned at the initial location turning OFF the VCHP. The against gravity working conditions showed a colder reservoir and faster transients.

Design of intelligent mesoscale periodic array structures utilizing smart hydrogel

NASA Technical Reports Server (NTRS)

Sunkara, H. B.; Penn, B. G.; Frazier, D. O.; Weissman, J. M.; Asher, S. A.

1996-01-01

Mesoscale Periodic Array Structures (MPAS, also known as crystalline colloidal arrays), composed of aqueous or nonaqueous dispersions of self-assembled submicron colloidal spheres are emerging toward the development of advanced optical devices for technological applications. This is because of their unique optical diffraction properties and the ease with which these intriguing properties can be modulated experimentally. Moreover our recent advancements in this area which include 'locking' the liquid MPAS into solid or semisolid polymer matrices for greater stability with longer life span, and incorporation of CdS quantum dots and laser dyes into colloidal spheres to obtain nonlinear optical (NLO) responses further corroborate the use of MPAS in optical technology. Our long term goal is fabrication of all-optical and electro-optical devices such as spatial light modulators for optical signal processing and flat panel display devices by utilizing intelligent nonlinear periodic array structural materials. Here we show further progress in the design of novel linear MPAS which have the ability to sense and respond to an external source such as temperature. This is achieved by combining the self-assembly properties of polymer colloidal spheres and thermoshrinking properties of smart polymer gels. At selected temperatures the periodic array efficiently Bragg diffracts light and transmits most of the light at other temperatures. Hence these intelligent systems are of potential use as fixed notch filters optical switches or limiters to protect delicate optical sensors from high intensity laser radiation.

3D treatment planning systems.

PubMed

Saw, Cheng B; Li, Sicong

2018-01-01

Three-dimensional (3D) treatment planning systems have evolved and become crucial components of modern radiation therapy. The systems are computer-aided designing or planning softwares that speed up the treatment planning processes to arrive at the best dose plans for the patients undergoing radiation therapy. Furthermore, the systems provide new technology to solve problems that would not have been considered without the use of computers such as conformal radiation therapy (CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT). The 3D treatment planning systems vary amongst the vendors and also the dose delivery systems they are designed to support. As such these systems have different planning tools to generate the treatment plans and convert the treatment plans into executable instructions that can be implemented by the dose delivery systems. The rapid advancements in computer technology and accelerators have facilitated constant upgrades and the introduction of different and unique dose delivery systems than the traditional C-arm type medical linear accelerators. The focus of this special issue is to gather relevant 3D treatment planning systems for the radiation oncology community to keep abreast of technology advancement by assess the planning tools available as well as those unique "tricks or tips" used to support the different dose delivery systems. Copyright © 2018 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

Electrochemical air revitalization system optimization investigation

NASA Technical Reports Server (NTRS)

Woods, R. R.; Schubert, F. H.; Hallick, T. M.

1975-01-01

A program to characterize a Breadboard of an Electrochemical Air Revitalization System (BEARS) was successfully completed. The BEARS is composed of three components: (1) a water vapor electrolysis module (WVEM) for O2 production and partial humidity control, (2) an electrochemical depolarized carbon dioxide concentrator module (EDCM) for CO2 control, and (3) a power-sharing controller, designed to utilize the power produced by the EDCM to partially offset the WVEM power requirements. It is concluded from the results of this work that the concept of electrochemical air revitalization with power-sharing is a viable solution to the problem of providing a localized topping force for O2 generation, CO2 removal and partial humidity control aboard manned spacecraft. Continued development of the EARS concept is recommended, applying the operational experience and limits identified during the BEARS program to testing of a one-man capacity system and toward the development of advanced system controls to optimize EARS operation for given interfaces and requirements. Successful completion of this development will produce timely technology necessary to plan future advanced environmental control and life support system programs and experiments.

GLOBECOM '87 - Global Telecommunications Conference, Tokyo, Japan, Nov. 15-18, 1987, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference on global telecommunications discusses topics in the fields of Integrated Services Digital Network (ISDN) technology field trial planning and results to date, motion video coding, ISDN networking, future network communications security, flexible and intelligent voice/data networks, Asian and Pacific lightwave and radio systems, subscriber radio systems, the performance of distributed systems, signal processing theory, satellite communications modulation and coding, and terminals for the handicapped. Also discussed are knowledge-based technologies for communications systems, future satellite transmissions, high quality image services, novel digital signal processors, broadband network access interface, traffic engineering for ISDN design and planning, telecommunications software, coherent optical communications, multimedia terminal systems, advanced speed coding, portable and mobile radio communications, multi-Gbit/second lightwave transmission systems, enhanced capability digital terminals, communications network reliability, advanced antimultipath fading techniques, undersea lightwave transmission, image coding, modulation and synchronization, adaptive signal processing, integrated optical devices, VLSI technologies for ISDN, field performance of packet switching, CSMA protocols, optical transport system architectures for broadband ISDN, mobile satellite communications, indoor wireless communication, echo cancellation in communications, and distributed network algorithms.

Recent advances and product enhancements in reflective cholesteric displays

NASA Astrophysics Data System (ADS)

Khan, Asad; Schneider, Tod; Miller, Nick; Marhefka, Duane; Ernst, Todd; Nicholson, Forrest; Doane, Joseph W.

2005-04-01

Bistable reflective cholesteric displays are a liquid crystal display technology developed to fill a market need for very low power displays on a low-cost, high resolution passive matrix. Their unique look, high reflectivity, bistability, and simple structure make them an ideal flat panel display choice for handheld or other portable devices where small lightweight batteries with long lifetimes are important. We discuss recent advances in cholesteric display technology at Kent Displays such as progress towards single layer black and white displays, standard products, lower cost display modules, and various interface options for cholesteric display applications. It will be shown that inclusion of radio frequency (rf) control options and serial peripheral interface (spi) can greatly enhance the cholesteric display module market penetration by enabling quick integration into end devices. Finally, some discussion will be on the progress of the development of flexible reflective cholesteric displays. These flexible displays can dramatically change industrial design methods by enabling curved surfaces with displays integrated in them. Additional discussion in the paper will include applications of various display modes including signs, hand held instrumentation, and the electronic book and reader.

Innovative and Advanced Coupled Neutron Transport and Thermal Hydraulic Method (Tool) for the Design, Analysis and Optimization of VHTR/NGNP Prismatic Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rahnema, Farzad; Garimeela, Srinivas; Ougouag, Abderrafi

2013-11-29

This project will develop a 3D, advanced coarse mesh transport method (COMET-Hex) for steady- state and transient analyses in advanced very high-temperature reactors (VHTRs). The project will lead to a coupled neutronics and thermal hydraulic (T/H) core simulation tool with fuel depletion capability. The computational tool will be developed in hexagonal geometry, based solely on transport theory without (spatial) homogenization in complicated 3D geometries. In addition to the hexagonal geometry extension, collaborators will concurrently develop three additional capabilities to increase the code’s versatility as an advanced and robust core simulator for VHTRs. First, the project team will develop and implementmore » a depletion method within the core simulator. Second, the team will develop an elementary (proof-of-concept) 1D time-dependent transport method for efficient transient analyses. The third capability will be a thermal hydraulic method coupled to the neutronics transport module for VHTRs. Current advancements in reactor core design are pushing VHTRs toward greater core and fuel heterogeneity to pursue higher burn-ups, efficiently transmute used fuel, maximize energy production, and improve plant economics and safety. As a result, an accurate and efficient neutron transport, with capabilities to treat heterogeneous burnable poison effects, is highly desirable for predicting VHTR neutronics performance. This research project’s primary objective is to advance the state of the art for reactor analysis.« less

Advanced induction accelerator designs for ground based and space based FELs

NASA Astrophysics Data System (ADS)

Birx, Daniel

1994-04-01

The primary goal of this program was to improve the performance of induction accelerators with particular regards to their being used to drive Free Electron Lasers (FEL's). It is hoped that FEL's operating at visible wavelengths might someday be used to beam power from earth to extraterrestrial locations. One application of this technology might be strategic theater defense, but this power source might be used to propel vehicles or supplement solar energized systems. Our path toward achieving this goal was directed first toward optimization of the nonlinear magnetic material used in induction accelerator construction and secondly at the overall design in terms of cost, size and efficiency. We began this research effort with an in depth study into the properties of various nonlinear magnetic materials. With the data on nonlinear magnetic materials, so important to the optimization of efficiency, in hand, we envisioned a new induction accelerator design where all of the components were packaged together in one container. This induction accelerator module would combine an /ll-solid-state, nonlinear magnetic driver and the induction accelerator cells all in one convenient package. Each accelerator module (denoted SNOMAD-IVB) would produce 1.0 MeV of acceleration with the exception of the SNOMAD-IV injector module which would produce 0.5 MeV of acceleration for an electron beam current up to 1000 amperes.

Development of a Broad High-Energy Gamma-Ray Telescope using Silicon Strip Detectors

NASA Technical Reports Server (NTRS)

Michelson, Peter F.

1998-01-01

The research effort has led to the development and demonstration of technology to enable the design and construction of a next-generation high-energy gamma-ray telescope that operates in the pair-production regime (E greater than 10 MeV). In particular, the technology approach developed is based on silicon-strip detector technology. A complete instrument concept based on this technology for the pair-conversion tracker and the use of CsI(T1) crystals for the calorimeter is now the baseline instrument concept for the Gamma-ray Large Area Space Telescope (GLAST) mission. GLAST is NASA's proposed high-energy gamma-ray mission designed to operate in the energy range from 10 MeV to approximately 300 GeV. GLAST, with nearly 100 times the sensitivity of EGRET, operates through pair conversion of gamma-rays and measurement of the direction and energy of the resulting e (+) - e (-) shower. The baseline design, developed with support from NASA includes a charged particle anticoincidence shield, a tracker/converter made of thin sheets of high-Z material interspersed with Si strip detectors, a CsI calorimeter and a programmable data trigger and acquisition system. The telescope is assembled as an array of modules or towers. Each tower contains elements of the tracker, calorimeter, and anticoincidence system. As originally proposed, the telescope design had 49 modules. In the more optimized design that emerged at the end of the grant period the individual modules are larger and the total number in the GLAST array is 25. Also the calorimeter design was advanced substantially to the point that it has a self-contained imaging capability, albeit much cruder than the tracker.

Uniform field loop-gap resonator and rectangular TEU02 for aqueous sample EPR at 94 GHz

NASA Astrophysics Data System (ADS)

Sidabras, Jason W.; Sarna, Tadeusz; Mett, Richard R.; Hyde, James S.

2017-09-01

In this work we present the design and implementation of two uniform-field resonators: a seven-loop-six-gap loop-gap resonator (LGR) and a rectangular TEU02 cavity resonator. Each resonator has uniform-field-producing end-sections. These resonators have been designed for electron paramagnetic resonance (EPR) of aqueous samples at 94 GHz. The LGR geometry employs low-loss Rexolite end-sections to improve the field homogeneity over a 3 mm sample region-of-interest from near-cosine distribution to 90% uniform. The LGR was designed to accommodate large degassable Polytetrafluorethylen (PTFE) tubes (0.81 mm O.D.; 0.25 mm I.D.) for aqueous samples. Additionally, field modulation slots are designed for uniform 100 kHz field modulation incident at the sample. Experiments using a point sample of lithium phthalocyanine (LiPC) were performed to measure both the uniformity of the microwave magnetic field and 100 kHz field modulation, and confirm simulations. The rectangular TEU02 cavity resonator employs over-sized end-sections with sample shielding to provide an 87% uniform field for a 0.1 × 2 × 6 mm3 sample geometry. An evanescent slotted window was designed for light access to irradiate 90% of the sample volume. A novel dual-slot iris was used to minimize microwave magnetic field perturbations and maintain cross-sectional uniformity. Practical EPR experiments using the application of light irradiated rose bengal (4,5,6,7-tetrachloro-2‧,4‧,5‧,7‧-tetraiodofluorescein) were performed in the TEU02 cavity. The implementation of these geometries providing a practical designs for uniform field resonators that continue resonator advancements towards quantitative EPR spectroscopy.

Advanced Data Acquisition Systems

NASA Technical Reports Server (NTRS)

Perotti, J.

2003-01-01

Current and future requirements of the aerospace sensors and transducers field make it necessary for the design and development of new data acquisition devices and instrumentation systems. New designs are sought to incorporate self-health, self-calibrating, self-repair capabilities, allowing greater measurement reliability and extended calibration cycles. With the addition of power management schemes, state-of-the-art data acquisition systems allow data to be processed and presented to the users with increased efficiency and accuracy. The design architecture presented in this paper displays an innovative approach to data acquisition systems. The design incorporates: electronic health self-check, device/system self-calibration, electronics and function self-repair, failure detection and prediction, and power management (reduced power consumption). These requirements are driven by the aerospace industry need to reduce operations and maintenance costs, to accelerate processing time and to provide reliable hardware with minimum costs. The project's design architecture incorporates some commercially available components identified during the market research investigation like: Field Programmable Gate Arrays (FPGA) Programmable Analog Integrated Circuits (PAC IC) and Field Programmable Analog Arrays (FPAA); Digital Signal Processing (DSP) electronic/system control and investigation of specific characteristics found in technologies like: Electronic Component Mean Time Between Failure (MTBF); and Radiation Hardened Component Availability. There are three main sections discussed in the design architecture presented in this document. They are the following: (a) Analog Signal Module Section, (b) Digital Signal/Control Module Section and (c) Power Management Module Section. These sections are discussed in detail in the following pages. This approach to data acquisition systems has resulted in the assignment of patent rights to Kennedy Space Center under U.S. patent # 6,462,684. Furthermore, NASA KSC commercialization office has issued licensing rights to Circuit Avenue Netrepreneurs, LLC , a minority-owned business founded in 1999 located in Camden, NJ.

Growth and development of Arabidopsis in the Advanced Biological Research System (ABRS) hardware designed for the International Space Station

NASA Astrophysics Data System (ADS)

Savidge, Rodney

Wild type (Col 0) Arabidopsis thaliana were grown in a growth chamber within the single mid-deck sized Advanced Biological Research System (ABRS) spaceflight hardware developed by NASA Kennedy Space Center. Before beginning this experiment, the plants, each rooted in individual transferable tubes containing nutrients, were cultivated hydroponically on halfstrength Hoagland's solution beneath either LED lighting similar to that provided by the ABRS growth chamber or white fluorescent lighting. The leaves of the basal whorl of plants pre-grown in ABRS lighting were small and purplish at the start of the experiment, whereas those under fluorescent lighting were larger and green. The plants were transferred to the ABRS soon after their inflorescence axes had started to elongate, and thereafter they were maintained under preset conditions (22 o C, approximately 1500 ppm CO2 , predominantly 125 µmol m-2 s-1 PAR) with pulses of water provided at 1-3 d intervals (as needed) to the module into which the root tubes were inserted. That module was pre-treated with half-strength Hoagland's nutrient solution on day 0, but no additional nutrients were provided the plants thereafter. Strong primary growth of all inflorescence stems occurred soon after initiating the ABRS experiment, and the plants began forming an overarching canopy of flowering stems beneath the LED lighting module within two weeks. After 38 days the root module was littered with seeds, siliques and abscised leaves, but all plants remained alive. Plants pre-grown in ABRS lighting were more advanced toward senescence, and leaves and stems of plants pre-grown in fluorescent lighting although greener were also acquiring a purplish hue. Microscopy revealed that the flowering stems achieved no secondary growth; however, progressive inward conversion of pith parenchyma into sclerenchyma cells did occur resulting in the inflorescence stems becoming abnormally woody.

Advanced Cloning Tools for Construction of Designer Cellulosomes.

PubMed

Kahn, Amaranta; Bayer, Edward A; Moraïs, Sarah

2018-01-01

Cellulose deconstruction is achieved in nature through two main enzymatic paradigms, i.e., free enzymes and enzymatic complexes (called cellulosomes). Gaining insights into the mechanism of action and synergy among the different cellulases is of high interest, notably in the field of renewable energy, and specifically, for the conversion of cellulosic biomass to soluble sugars, en route to biofuels. In this context, designer cellulosomes are artificially assembled, chimaeric protein complexes that are used as a tool to comparatively study cellulose degradation by different enzymatic paradigms, and could also serve to improve cellulose deconstruction. Various molecular biology techniques are employed in order to design and engineer the various components of designer cellulosomes. In this chapter, we describe the cloning processes through which the appropriate modules are selected and assembled at the molecular level.

Electronics for CMS Endcap Muon Level-1 Trigger System Phase-1 and HL LHC upgrades

NASA Astrophysics Data System (ADS)

Madorsky, A.

2017-07-01

To accommodate high-luminosity LHC operation at a 13 TeV collision energy, the CMS Endcap Muon Level-1 Trigger system had to be significantly modified. To provide robust track reconstruction, the trigger system must now import all available trigger primitives generated by the Cathode Strip Chambers and by certain other subsystems, such as Resistive Plate Chambers (RPC). In addition to massive input bandwidth, this also required significant increase in logic and memory resources. To satisfy these requirements, a new Sector Processor unit has been designed. It consists of three modules. The Core Logic module houses the large FPGA that contains the track-finding logic and multi-gigabit serial links for data exchange. The Optical module contains optical receivers and transmitters; it communicates with the Core Logic module via a custom backplane section. The Pt Lookup table (PTLUT) module contains 1 GB of low-latency memory that is used to assign the final Pt to reconstructed muon tracks. The μ TCA architecture (adopted by CMS) was used for this design. The talk presents the details of the hardware and firmware design of the production system based on Xilinx Virtex-7 FPGA family. The next round of LHC and CMS upgrades starts in 2019, followed by a major High-Luminosity (HL) LHC upgrade starting in 2024. In the course of these upgrades, new Gas Electron Multiplier (GEM) detectors and more RPC chambers will be added to the Endcap Muon system. In order to keep up with all these changes, a new Advanced Processor unit is being designed. This device will be based on Xilinx UltraScale+ FPGAs. It will be able to accommodate up to 100 serial links with bit rates of up to 25 Gb/s, and provide up to 2.5 times more logic resources than the device used currently. The amount of PTLUT memory will be significantly increased to provide more flexibility for the Pt assignment algorithm. The talk presents preliminary details of the hardware design program.

Systems integration and demonstration of advanced reusable structure for ALS

NASA Technical Reports Server (NTRS)

Gibbins, Martin N.

1991-01-01

The objective was to investigate the potential of advanced material to achieve life cycle cost (LCC) benefits for reusable structure on the advanced launch system. Three structural elements were investigated - all components of an Advanced Launch System reusable propulsion/avionics module. Leading aeroshell configurations included sandwich structure using titanium, graphite/polyimide (Gr/PI), or high-temperature aluminum (HTA) face sheets. Thrust structure truss concepts used titanium, graphite/epoxy, or silicon carbide/aluminum struts. Leading aft bulkhead concepts employed graphite epoxy and aluminum. The technical effort focused on the aeroshell because the greatest benefits were expected there. Thermal analyses show the structural temperature profiles during operation. Finite element analyses show stresses during splash-down. Weight statements and manufacturing cost estimates were prepared for calculation of LCC for each design. The Gr/PI aeroshell showed the lowest potential LCC, but the HTA aeroshell was judged to be lower risk. A technology development plan was prepared to validate the applicable structural technology.

Liquid crystalline fiber optic colorimeter for hydrostatic pressure measurement

NASA Astrophysics Data System (ADS)

Wolinski, Tomasz R.; Bajdecki, Waldemar K.; Domanski, Andrzej W.; Karpierz, Miroslaw A.; Konopka, Witold; Nasilowski, T.; Sierakowski, Marek W.; Swillo, Marcin; Dabrowski, Roman S.; Nowinowski-Kruszelnicki, Edward; Wasowski, Janusz

2001-08-01

This paper presents results of tests performed on a fiber optic system of liquid crystalline transducer for hydrostatic pressure monitoring based on properties of colorimetry. The system employs pressure-induced deformations occurring in liquid crystalline (LC) cells configured in a homogeneous Frederiks geometry. The sensor is compared of a round LC cell placed inside a specially designed pressure chamber. As a light source we used a typical diode operating at red wavelength and modulated using standard techniques. The pressure transducer was connected to a computer with a specially designed interface built on the bas of advanced ADAM modules. Results indicate that the system offers high response to pressure with reduced temperature sensitivity and, depending on the LC cell used, can be adjusted for monitoring of low hydrostatic pressures up to 6 MPa. These studies have demonstrated the feasibility of fiber optic liquid crystal colorimeter for hydrostatic pressure sensing specially dedicated to pipe- lines, mining instrumentation, and process-control technologies.

Advanced Stirling receiver development program, phase 1

NASA Technical Reports Server (NTRS)

Lurio, Charles A.

1990-01-01

Critical technology experiments were designed and developed to evaluate the Stirling cavity heat pipe receiver for a space solar power system. Theoretical criteria were applied to the design of a module for containing energy storage phase change material while avoiding thermal ratcheting. Zero-g drop tower tests, without phase change, were conducted to affirm that the bubble location required to avoid ratcheting could be achieved without the use of container materials that are wetted by the phase change material. A full scale module was fabricated, but not tested. A fabrication method was successfully developed for the sodium evaporator dome, with a sintered screen wick, to be used as the focal point for the receiver. Crushing of the screen during hydroforming was substantially reduced over the results of other researchers by using wax impregnation. Superheating of the sodium in the wick under average flux conditions is expected to be under 10K. A 2000K furnace which will simulate solar flux conditions for testing the evaporator dome was successfully built and tested.

Low-current traveling wave tube for use in the microwave power module

NASA Technical Reports Server (NTRS)

Palmer, Raymond W.; Ramins, Peter; Force, Dale A.; Dayton, James A.; Ebihara, Ben T.; Gruber, Robert P.

1993-01-01

The results of a traveling-wave-tube/multistage depressed-collector (TWT-MDC) design study in support of the Advanced Research Projects Agency/Department of Defense (ARPA/DOD) Microwave Power Module (MPM) Program are described. The study stressed the possible application of dynamic and other tapers to the RF output circuit of the MPM traveling wave tube as a means of increasing the RF and overall efficiencies and reducing the required beam current (perveance). The results indicate that a highly efficient, modified dynamic velocity taper (DVT) circuit can be designed for the broadband MPM application. The combination of reduced cathode current (lower perveance) and increased RF efficiency leads to (1) a substantially higher overall efficiency and reduction in the prime power to the MPM, and (2) substantially reduced levels of MDC and MPM heat dissipation, which simplify the cooling problems. However, the selected TWT circuit parameters need to be validated by cold test measurements on actual circuits.

Simulating x-ray telescopes with McXtrace: a case study of ATHENA's optics

NASA Astrophysics Data System (ADS)

Ferreira, Desiree D. M.; Knudsen, Erik B.; Westergaard, Niels J.; Christensen, Finn E.; Massahi, Sonny; Shortt, Brian; Spiga, Daniele; Solstad, Mathias; Lefmann, Kim

2016-07-01

We use the X-ray ray-tracing package McXtrace to simulate the performance of X-ray telescopes based on Silicon Pore Optics (SPO) technologies. We use as reference the design of the optics of the planned X-ray mission Advanced Telescope for High ENergy Astrophysics (ATHENA) which is designed as a single X-ray telescope populated with stacked SPO substrates forming mirror modules to focus X-ray photons. We show that is possible to simulate in detail the SPO pores and qualify the use of McXtrace for in-depth analysis of in-orbit performance and laboratory X-ray test results.

Realization of compact, passively-cooled, high-flux photovoltaic prototypes

NASA Astrophysics Data System (ADS)

Feuermann, Daniel; Gordon, Jeffrey M.; Horne, Steve; Conley, Gary; Winston, Roland

2005-08-01

The materialization of a recent conceptual advance in high-flux photovoltaic concentrators into first-generation prototypes is reported. Our design strategy includes a tailored imaging dual-mirror (aplanatic) system, with a tapered glass rod that enhances concentration and accommodates larger optical errors. Designs were severely constrained by the need for ultra-compact (minimal aspect ratio) modules, simple passive heat rejection, liberal optical tolerances, incorporating off-the-shelf commercial solar cells, and pragmatic considerations of affordable fabrication technologies. Each unit has a geometric concentration of 625 and irradiates a single square 100 mm2 triple-junction high-efficiency solar cell at a net flux concentration of 500.

Research Studies on Advanced Optical Module/Head Designs for Optical Data Storage

NASA Technical Reports Server (NTRS)

1992-01-01

Preprints are presented from the recent 1992 Optical Data Storage meeting in San Jose. The papers are divided into the following topical areas: Magneto-optical media (Modeling/design and fabrication/characterization/testing); Optical heads (holographic optical elements); and Optical heads (integrated optics). Some representative titles are as follow: Diffraction analysis and evaluation of several focus and track error detection schemes for magneto-optical disk systems; Proposal for massively parallel data storage system; Transfer function characteristics of super resolving systems; Modeling and measurement of a micro-optic beam deflector; Oxidation processes in magneto-optic and related materials; and A modal analysis of lamellar diffraction gratings in conical mountings.

Multifunctional combinatorial-designed nanoparticles for nucleic acid therapy

NASA Astrophysics Data System (ADS)

Amiji, Mansoor M.

2016-05-01

Recent advances in biomedical sciences, especially in the field of human genetics, is increasingly considered to facilitate a new frontier in development of novel disease-modifying therapeutics. One of major challenges in the development of nucleic acid therapeutics is efficient and specific delivery of the molecules to the target tissue and cell upon systemic administration. In this report, I discuss our strategy to develop combinatorial-designed multifunctional nanoparticle assemblies based on natural biocompatible and biodegradable polymers for nucleic acid delivery in: (1) overcoming tumor drug resistance and (2) genetic modulation of macrophage functional phenotype from M1 to M2 in treatment of inflammatory diseases.

A sub-μs thermal time constant electrically driven Pt nanoheater: thermo-dynamic design and frequency characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ottonello Briano, Floria, E-mail: floria@kth.se; Sohlström, Hans; Forsberg, Fredrik

2016-05-09

Metal nanowires can emit coherent polarized thermal radiation, work as uncooled bolometers, and provide localized heating. In this paper, we engineer the temperature dynamics of electrically driven Pt nanoheaters on a silicon-on-insulator substrate. We present three designs and we electrically characterize and model their thermal impedance in the frequency range from 3 Hz to 3 MHz. Finally, we show a temperature modulation of 300 K while consuming less than 5 mW of power, up to a frequency of 1.3 MHz. This result can lead to significant advancements in thermography and absorption spectroscopy.

Project T.E.A.M. (Technical Education Advancement Modules). Final Report.

ERIC Educational Resources Information Center

Greenville Technical Coll., SC.

Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training, created an introductory technical training program and a consumer education package emphasizing the benefits of technical training. The curriculum and training focus of the project began with an assessment of employee needs in…

A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering

PubMed Central

Webber, Matthew J.; Khan, Omar F.; Sydlik, Stefanie A.; Tang, Benjamin C.; Langer, Robert

2016-01-01

Scaffolds have been broadly applied within tissue engineering and regenerative medicine to regenerate, replace, or augment diseased or damaged tissue. For a scaffold to perform optimally, several design considerations must be addressed, with an eye toward the eventual form, function, and tissue site. The chemical and mechanical properties of the scaffold must be tuned to optimize the interaction with cells and surrounding tissues. For complex tissue engineering, mass transport limitations, vascularization, and host tissue integration are important considerations. As the tissue architecture to be replaced becomes more complex and hierarchical, scaffold design must also match this complexity to recapitulate a functioning tissue. We outline these design constraints and highlight creative and emerging strategies to overcome limitations and modulate scaffold properties for optimal regeneration. We also highlight some of the most advanced strategies that have seen clinical application and discuss the hurdles that must be overcome for clinical use and commercialization of tissue engineering technologies. Finally, we provide a perspective on the future of scaffolds as a functional contributor to advancing tissue engineering and regenerative medicine. PMID:25201605

Common hyperspectral image database design

NASA Astrophysics Data System (ADS)

Tian, Lixun; Liao, Ningfang; Chai, Ali

2009-11-01

This paper is to introduce Common hyperspectral image database with a demand-oriented Database design method (CHIDB), which comprehensively set ground-based spectra, standardized hyperspectral cube, spectral analysis together to meet some applications. The paper presents an integrated approach to retrieving spectral and spatial patterns from remotely sensed imagery using state-of-the-art data mining and advanced database technologies, some data mining ideas and functions were associated into CHIDB to make it more suitable to serve in agriculture, geological and environmental areas. A broad range of data from multiple regions of the electromagnetic spectrum is supported, including ultraviolet, visible, near-infrared, thermal infrared, and fluorescence. CHIDB is based on dotnet framework and designed by MVC architecture including five main functional modules: Data importer/exporter, Image/spectrum Viewer, Data Processor, Parameter Extractor, and On-line Analyzer. The original data were all stored in SQL server2008 for efficient search, query and update, and some advance Spectral image data Processing technology are used such as Parallel processing in C#; Finally an application case is presented in agricultural disease detecting area.

A perspective on the clinical translation of scaffolds for tissue engineering.

PubMed

Webber, Matthew J; Khan, Omar F; Sydlik, Stefanie A; Tang, Benjamin C; Langer, Robert

2015-03-01

Scaffolds have been broadly applied within tissue engineering and regenerative medicine to regenerate, replace, or augment diseased or damaged tissue. For a scaffold to perform optimally, several design considerations must be addressed, with an eye toward the eventual form, function, and tissue site. The chemical and mechanical properties of the scaffold must be tuned to optimize the interaction with cells and surrounding tissues. For complex tissue engineering, mass transport limitations, vascularization, and host tissue integration are important considerations. As the tissue architecture to be replaced becomes more complex and hierarchical, scaffold design must also match this complexity to recapitulate a functioning tissue. We outline these design constraints and highlight creative and emerging strategies to overcome limitations and modulate scaffold properties for optimal regeneration. We also highlight some of the most advanced strategies that have seen clinical application and discuss the hurdles that must be overcome for clinical use and commercialization of tissue engineering technologies. Finally, we provide a perspective on the future of scaffolds as a functional contributor to advancing tissue engineering and regenerative medicine.

Accurate determination of segmented X-ray detector geometry

PubMed Central

Yefanov, Oleksandr; Mariani, Valerio; Gati, Cornelius; White, Thomas A.; Chapman, Henry N.; Barty, Anton

2015-01-01

Recent advances in X-ray detector technology have resulted in the introduction of segmented detectors composed of many small detector modules tiled together to cover a large detection area. Due to mechanical tolerances and the desire to be able to change the module layout to suit the needs of different experiments, the pixels on each module might not align perfectly on a regular grid. Several detectors are designed to permit detector sub-regions (or modules) to be moved relative to each other for different experiments. Accurate determination of the location of detector elements relative to the beam-sample interaction point is critical for many types of experiment, including X-ray crystallography, coherent diffractive imaging (CDI), small angle X-ray scattering (SAXS) and spectroscopy. For detectors with moveable modules, the relative positions of pixels are no longer fixed, necessitating the development of a simple procedure to calibrate detector geometry after reconfiguration. We describe a simple and robust method for determining the geometry of segmented X-ray detectors using measurements obtained by serial crystallography. By comparing the location of observed Bragg peaks to the spot locations predicted from the crystal indexing procedure, the position, rotation and distance of each module relative to the interaction region can be refined. We show that the refined detector geometry greatly improves the results of experiments. PMID:26561117

Next-generation avionics packaging and cooling 'test results from a prototype system'

NASA Astrophysics Data System (ADS)

Seals, J. D.

The author reports on the design, material characteristics, and test results obtained under the US Air Force's advanced aircraft avionics packaging technologies (AAAPT) program, whose charter is to investigate new designs and technologies for reliable packaging, interconnection, and thermal management. Under this program, AT&T Bell Laboratories has completed the preliminary testing of and is evaluating a number of promising materials and technologies, including conformal encapsulation, liquid flow-through cooling, and a cyanate ester backplane. A fifty-two module system incorporating these and and other technologies has undergone preliminary cooling efficiency, shock, sine and random vibration, and maintenance testing. One of the primary objectives was to evaluate the interaction compatibility of new materials and designs with other components in the system.

Static Feed Water Electrolysis Subsystem Testing and Component Development

NASA Technical Reports Server (NTRS)

Koszenski, E. P.; Schubert, F. H.; Burke, K. A.

1983-01-01

A program was carried out to develop and test advanced electrochemical cells/modules and critical electromechanical components for a static feed (alkaline electrolyte) water electrolysis oxygen generation subsystem. The accomplishments were refurbishment of a previously developed subsystem and successful demonstration for a total of 2980 hours of normal operation; achievement of sustained one-person level oxygen generation performance with state-of-the-art cell voltages averaging 1.61 V at 191 ASF for an operating temperature of 128F (equivalent to 1.51V when normalized to 180F); endurance testing and demonstration of reliable performance of the three-fluid pressure controller for 8650 hours; design and development of a fluid control assembly for this subsystem and demonstration of its performance; development and demonstration at the single cell and module levels of a unitized core composite cell that provides expanded differential pressure tolerance capability; fabrication and evaluation of a feed water electrolyte elimination five-cell module; and successful demonstration of an electrolysis module pressurization technique that can be used in place of nitrogen gas during the standby mode of operation to maintain system pressure and differential pressures.

Studies on Modulation of Gut Microbiota by Wine Polyphenols: From Isolated Cultures to Omic Approaches

PubMed Central

Dueñas, Montserrat; Cueva, Carolina; Muñoz-González, Irene; Jiménez-Girón, Ana; Sánchez-Patán, Fernando; Santos-Buelga, Celestino; Moreno-Arribas, M. Victoria; Bartolomé, Begoña

2015-01-01

Moderate consumption of wine seems to produce positive health effects derived from the occurrence of bioactive polyphenols. The gut microbiota is involved in the metabolism of phenolic compounds, and these compounds and/or their metabolites may modulate gut microbiota through the stimulation of the growth of beneficial bacteria and the inhibition of pathogenic bacteria. The characterization of bacterial metabolites derived from polyphenols is essential in order to understand their effects, including microbial modulation, and therefore to associate dietary intake with particular health effects. This review aims to summarize the current information about the two-way “wine polyphenols–gut microbiota” interaction, from a perspective based on the experimental and analytical designs used. The availability of advanced methods for monitoring bacterial communities, along with the combination of in vitro and in vivo models, could help to assess the metabolism of polyphenols in the human body and to monitor total bacterial communities, and, therefore, to elucidate the implications of diet on the modulation of microbiota for delivering health benefits. PMID:26785335

Field experiment of 800× off-axis XR-Köhler concentrator module on a carousel tracker

NASA Astrophysics Data System (ADS)

Yamada, Noboru; Okamoto, Kazuya; Ijiro, Toshikazu; Suzuki, Takao; Maemura, Toshihiko; Kawaguchi, Takashi; Takahashi, Hiroshi; Sato, Takashi; Hernandez, Maikel; Benitez, Pablo; Chaves, Julio; Cvetkovic, Aleksandra; Vilaplana, Juan; Mohedano, Ruben; Mendes-Lopes, Joao; Miñano, Juan Carlos

2013-09-01

This paper presents the design and preliminary experimental results of a concentrator-type photovoltaic module based on a free-form off-axis 800×XR-Köhler concentrator. The off-axis XR-Köhler concentrator is one of the advanced concentrators that perform high concentration with a large acceptance angle and excellent irradiance uniformity on a solar cell. As a result of on-sun characterization of the unglazed single-cell unit test rig, the temperature-corrected DC module efficiency was 32.2% at 25 °C without an anti-reflective (AR) coating on the secondary optics, and the acceptance angle was more than ±1.0°. In addition, the non-corrected DC efficiency of an individual cell in a glazed 8-cell unit module mounted on a carousel tracking system was measured. The individual efficiency deviated in the range of 24.3-27.4%, owing to the mirror shape and alignment errors. The resultant series-connected efficiency was approximately 25% at direct normal irradiation (DNI) of 770 W/m2.

Advanced Modulation and Coding Technology Conference

NASA Technical Reports Server (NTRS)

1992-01-01

The objectives, approach, and status of all current LeRC-sponsored industry contracts and university grants are presented. The following topics are covered: (1) the LeRC Space Communications Program, and Advanced Modulation and Coding Projects; (2) the status of four contracts for development of proof-of-concept modems; (3) modulation and coding work done under three university grants, two small business innovation research contracts, and two demonstration model hardware development contracts; and (4) technology needs and opportunities for future missions.

HDL Based FPGA Interface Library for Data Acquisition and Multipurpose Real Time Algorithms

NASA Astrophysics Data System (ADS)

Fernandes, Ana M.; Pereira, R. C.; Sousa, J.; Batista, A. J. N.; Combo, A.; Carvalho, B. B.; Correia, C. M. B. A.; Varandas, C. A. F.

2011-08-01

The inherent parallelism of the logic resources, the flexibility in its configuration and the performance at high processing frequencies makes the field programmable gate array (FPGA) the most suitable device to be used both for real time algorithm processing and data transfer in instrumentation modules. Moreover, the reconfigurability of these FPGA based modules enables exploiting different applications on the same module. When using a reconfigurable module for various applications, the availability of a common interface library for easier implementation of the algorithms on the FPGA leads to more efficient development. The FPGA configuration is usually specified in a hardware description language (HDL) or other higher level descriptive language. The critical paths, such as the management of internal hardware clocks that require deep knowledge of the module behavior shall be implemented in HDL to optimize the timing constraints. The common interface library should include these critical paths, freeing the application designer from hardware complexity and able to choose any of the available high-level abstraction languages for the algorithm implementation. With this purpose a modular Verilog code was developed for the Virtex 4 FPGA of the in-house Transient Recorder and Processor (TRP) hardware module, based on the Advanced Telecommunications Computing Architecture (ATCA), with eight channels sampling at up to 400 MSamples/s (MSPS). The TRP was designed to perform real time Pulse Height Analysis (PHA), Pulse Shape Discrimination (PSD) and Pile-Up Rejection (PUR) algorithms at a high count rate (few Mevent/s). A brief description of this modular code is presented and examples of its use as an interface with end user algorithms, including a PHA with PUR, are described.

Conceptual design study for an advanced cab and visual system, volume 1

NASA Technical Reports Server (NTRS)

Rue, R. J.; Cyrus, M. L.; Garnett, T. A.; Nachbor, J. W.; Seery, J. A.; Starr, R. L.

1980-01-01

A conceptual design study was conducted to define requirements for an advanced cab and visual system. The rotorcraft system integration simulator is for engineering studies in the area of mission associated vehicle handling qualities. Principally a technology survey and assessment of existing and proposed simulator visual display systems, image generation systems, modular cab designs, and simulator control station designs were performed and are discussed. State of the art survey data were used to synthesize a set of preliminary visual display system concepts of which five candidate display configurations were selected for further evaluation. Basic display concepts incorporated in these configurations included: real image projection, using either periscopes, fiber optic bundles, or scanned laser optics; and virtual imaging with helmet mounted displays. These display concepts were integrated in the study with a simulator cab concept employing a modular base for aircraft controls, crew seating, and instrumentation (or other) displays. A simple concept to induce vibration in the various modules was developed and is described. Results of evaluations and trade offs related to the candidate system concepts are given, along with a suggested weighting scheme for numerically comparing visual system performance characteristics.

The modulation of savouring by prediction error and its effects on choice

PubMed Central

Iigaya, Kiyohito; Story, Giles W; Kurth-Nelson, Zeb; Dolan, Raymond J; Dayan, Peter

2016-01-01

When people anticipate uncertain future outcomes, they often prefer to know their fate in advance. Inspired by an idea in behavioral economics that the anticipation of rewards is itself attractive, we hypothesized that this preference of advance information arises because reward prediction errors carried by such information can boost the level of anticipation. We designed new empirical behavioral studies to test this proposal, and confirmed that subjects preferred advance reward information more strongly when they had to wait for rewards for a longer time. We formulated our proposal in a reinforcement-learning model, and we showed that our model could account for a wide range of existing neuronal and behavioral data, without appealing to ambiguous notions such as an explicit value for information. We suggest that such boosted anticipation significantly drives risk-seeking behaviors, most pertinently in gambling. DOI: http://dx.doi.org/10.7554/eLife.13747.001 PMID:27101365

Latest developments in the Advanced Photovoltaic Solar Array Program

NASA Technical Reports Server (NTRS)

Stella, Paul M.; Kurland, Richard M.

1990-01-01

In 1985, the Advanced Photovoltaic Solar Array (APSA) Program was established to demonstrate a producible array system with a specific power greater than 130 W/kg at a 10-kW (BOL) power level. The latest program phase completed fabrication and initial functional testing of a prototype wing representative of a full-scale 5-kW (BOL) wing (except truncated in length to about 1 kW), with weight characteristics that could meet the 130-W/kg (BOL) specific power goal using thin silicon solar cell modules and weight-efficient structural components. The wing configuration and key design details are reviewed, along with results from key component-level and wing-level tests. Projections for future enhancements that may be expected through the use of advanced solar cells and structural components are shown. Performance estimates are given for solar electric propulsion orbital transfer missions through the Van Allen radiation belts. The latest APSA program plans are presented.

Technology advancement of the static feed water electrolysis process

NASA Technical Reports Server (NTRS)

Schubert, F. H.; Wynveen, R. A.

1977-01-01

A program to advance the technology of oxygen- and hydrogen-generating subsystems based on water electrolysis was studied. Major emphasis was placed on static feed water electrolysis, a concept characterized by low power consumption and high intrinsic reliability. The static feed based oxygen generation subsystem consists basically of three subassemblies: (1) a combined water electrolysis and product gas dehumidifier module; (2) a product gas pressure controller and; (3) a cyclically filled water feed tank. Development activities were completed at the subsystem as well as at the component level. An extensive test program including single cell, subsystem and integrated system testing was completed with the required test support accessories designed, fabricated, and assembled. Mini-product assurance activities were included throughout all phases of program activities. An extensive number of supporting technology studies were conducted to advance the technology base of the static feed water electrolysis process and to resolve problems.

Recent technologic advances in multi-detector row cardiac CT.

PubMed

Halliburton, Sandra Simon

2009-11-01

Recent technical advances in multi-detector row CT have resulted in lower radiation dose, improved temporal and spatial resolution, decreased scan time, and improved tissue differentiation. Lower radiation doses have resulted from the use of pre-patient z collimators, the availability of thin-slice axial data acquisition, the increased efficiency of ECG-based tube current modulation, and the implementation of iterative reconstruction algorithms. Faster gantry rotation and the simultaneous use of two x-ray sources have led to improvements in temporal resolution, and gains in spatial resolution have been achieved through application of the flying x-ray focal-spot technique in the z-direction. Shorter scan times have resulted from the design of detector arrays with increasing numbers of detector rows and through the simultaneous use of two x-ray sources to allow higher helical pitch. Some improvement in tissue differentiation has been achieved with dual energy CT. This article discusses these recent technical advances in detail.

Computer-aided design of biological circuits using TinkerCell

PubMed Central

Bergmann, Frank T; Sauro, Herbert M

2010-01-01

Synthetic biology is an engineering discipline that builds on modeling practices from systems biology and wet-lab techniques from genetic engineering. As synthetic biology advances, efficient procedures will be developed that will allow a synthetic biologist to design, analyze and build biological networks. In this idealized pipeline, computer-aided design (CAD) is a necessary component. The role of a CAD application would be to allow efficient transition from a general design to a final product. TinkerCell is a design tool for serving this purpose in synthetic biology. In TinkerCell, users build biological networks using biological parts and modules. The network can be analyzed using one of several functions provided by TinkerCell or custom programs from third-party sources. Since best practices for modeling and constructing synthetic biology networks have not yet been established, TinkerCell is designed as a flexible and extensible application that can adjust itself to changes in the field. PMID:21327060

Advanced servo manipulator

DOEpatents

Holt, W.E.; Kuban, D.P.; Martin, H.L.

1988-10-25

An advanced servo manipulator has modular parts. Modular motor members drive individual input gears to control shoulder roll, shoulder pitch, elbow pitch, wrist yaw, wrist pitch, wrist roll, and tong spacing. The modules include a support member, a shoulder module for controlling shoulder roll, and a sleeve module attached to the shoulder module in fixed relation thereto. The shoulder roll sleeve module has an inner cylindrical member rotatable relative to the outer cylindrical member, and upon which a gear pod assembly is mounted. A plurality of shafts are driven by the gears, which are in turn driven by individual motor modules to transmit rotary power to control elbow pitch as well as to provide four different rotary shafts across the bendable elbow joint to supply rotary motive power to a wrist member and tong member. 41 figs.

Advanced servo manipulator

DOEpatents

Holt, William E.; Kuban, Daniel P.; Martin, H. Lee

1988-01-01

An advanced servo manipulator has modular parts. Modular motor members drive individual input gears to control shoulder roll, shoulder pitch, elbow pitch, wrist yaw, wrist pitch, wrist roll, and tong spacing. The modules include a support member, a shoulder module for controlling shoulder roll, and a sleeve module attached to the shoulder module in fixed relation thereto. The shoulder roll sleeve module has an inner cylindrical member rotatable relative to the outer cylindrical member, and upon which a gear pod assembly is mounted. A plurality of shafts are driven by the gears, which are in turn driven by individual motor modules to transmit rotary power to control elbow pitch as well as to provide four different rotary shafts across the bendable elbow joint to supply rotary motive power to a wrist member and tong member.

Design and performance of radioisotope space power systems based on OSC multitube AMTEC converter designs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, A.; Noravian, H.; Or, C.

1997-12-31

This paper extends the analytical procedure described in another paper in these proceedings to analyze a variety of compact and light-weight OSC-designed radioisotope-heated generators. Those generators employed General Purpose Heat Source (GPHS) modules and a converter containing sixteen AMTEC cells of OSC`s revised five-tube design with enhanced cell wall reflectivity described in a companion paper in these proceedings. OSC found that the performance of the generator is primarily a function of the thermal insulation between the outside of the generator`s 16 cells and the inside of its wall. After examining a variety of insulation options, it was found that themore » generator`s performance is optimized by employing a hybrid insulation system, in which the space between the cells is filled with fibrous Min-K insulation, and the generator walls are lined with tapered (i.e., graded-length) multifoil insulation. The OSC design results in a very compact generator, with eight AMTEC cells on each end of the heat source stack. The choice of the five-tube cells makes it possible to expand the BASE tube diameter without increasing the cell diameter. This is important because the eight cells mate well with the stacked GPHS modules. The OSC generator design includes a compliant heat source support and preload arrangement, to hold the heat source modules together during launch, and to maintain thermal contact conductance at the generator`s interfaces despite creep relaxation of its housing. The BOM and EOM (up to 15 years) performances of the revised generators were analyzed for two and three GPHS modules, both for fresh fuel and for aged fuel left over from a spare RTG (Radioisotope Thermoelectric Generator) fueled in 1982. The resulting power outputs were compared with JPL`s latest EOM power demand goals for the Pluto Express and Europa Orbiter missions, and with the generic goals of DOE`s Advanced Radioisotope Power System (ARPS) study. The OSC AMTEC designs yielded system efficiencies three to four times as high as present-generation RTGs.« less

Advanced photoelectric effect experiment beamline at Elettra: A surface science laboratory coupled with Synchrotron Radiation.

PubMed

Panaccione, G; Vobornik, I; Fujii, J; Krizmancic, D; Annese, E; Giovanelli, L; Maccherozzi, F; Salvador, F; De Luisa, A; Benedetti, D; Gruden, A; Bertoch, P; Polack, F; Cocco, D; Sostero, G; Diviacco, B; Hochstrasser, M; Maier, U; Pescia, D; Back, C H; Greber, T; Osterwalder, J; Galaktionov, M; Sancrotti, M; Rossi, G

2009-04-01

We report the main characteristics of the advanced photoelectric effect experiments beamline, operational at Elettra storage ring, featuring a fully independent double branch scheme obtained by the use of chicane undulators and able to keep polarization control in both linear and circular mode. The paper describes the novel technical solutions adopted, namely, (a) the design of a quasiperiodic undulator resulting in optimized suppression of higher harmonics over a large photon energy range (10-100 eV), (b) the thermal stability of optics under high heat load via cryocoolers, and (c) the end station interconnected setup allowing full access to off-beam and on-beam facilities and, at the same time, the integration of users' specialized sample growth chambers or modules.

Atacama Cosmology Telescope: Polarization calibration analysis for CMB measurements with ACTPol and Advanced ACTPol

NASA Astrophysics Data System (ADS)

Koopman, Brian; ACTPol Collaboration

2015-04-01

The Atacama Cosmology Telescope Polarimeter (ACTPol) is a polarization sensitive upgrade for the Atacama Cosmology Telescope, located at an elevation of 5190 m on Cerro Toco in Chile. Achieving first light in 2013, ACTPol is entering its third observation season. Advanced ACTPol is a next generation upgrade for ACTPol, with additional frequencies, polarization modulation, and new detector arrays, that will begin in 2016. I will first present an overview of the two projects and then focus on describing the methods used for polarization angle calibration of the ACTPol detectors. These methods utilize polarization ray tracing in the optical design software CODEV together with detector positions determined from planet observations and represent a critical input for mapping the polarization of the CMB.

Advanced Thermoplastic Polymers and Additive Manufacturing Applied to ISS Columbus Toolbox: Lessons Learnt and Results

NASA Astrophysics Data System (ADS)

Ferrino, Marinella; Secondo, Ottaviano; Sabbagh, Amir; Della Sala, Emilio

2014-06-01

In the frame of the International Space Station (ISS) Exploitation Program a new toolbox has been realized by TAS-I to accommodate the tools currently in use on the ISS Columbus Module utilizing full-scale prototypes obtained with 3D rapid prototyping. The manufacturing of the flight hardware by means of advanced thermoplastic polymer UL TEM 9085 and additive manufacturing Fused Deposition Modelling (FDM) technology represent innovative elements. In this paper, the results achieved and the lessons learned are analyzed to promote future technology know-how. The acquired experience confirmed that the additive manufacturing process allows to save time/cost and to realize new shapes/features to introduce innovation in products and future design processes for space applications.

Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors

NASA Astrophysics Data System (ADS)

Chiu, Nan-Fu; Huang, Teng-Yi; Kuo, Chun-Chuan

2015-05-01

We describe a fundamental study on the plasmonic properties and advanced biosensing mechanisms of functionalized graphene. We discuss a specific design using modified carboxyl groups, which can modulate surface plasmon (SP) coupling and provide an advantage for their binding to the sensing layer with high-performance affinity in an immunological reaction. The functionalized graphene-based surface plasmon resonance (SPR) biosensors have three advantages: high performance, high sensitivity, and excellent molecular kinetic response. In the future, functionalized graphene sheets will make a unique contribution to photonic and SPR diagnosis devices. We wish to highlight the essential characteristics of functionalized graphene-based SPR biosensors to assist researchers in developing and advancing suitable biosensors for unique applications.

Space station definition and preliminary design, WP-01. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Lenda, J. A.

1987-01-01

System activities are summarized and an overview of the system level engineering tasks performed are provided. Areas discussed include requirements, system test and verification, the advanced development plan, customer accommodations, software, growth, productivity, operations, product assurance and metrication. The hardware element study results are summarized. Overviews of recommended configurations are provided for the core module, the USL, the logistics elements, the propulsion subsystems, reboost, vehicle accommodations, and the smart front end. A brief overview is provided for costing activities.

Peptoid architectures: elaboration, actuation, and application.

PubMed

Yoo, Barney; Kirshenbaum, Kent

2008-12-01

Peptoids are peptidomimetic oligomers composed of N-substituted glycine units. Their convenient synthesis enables strict control over the sequence of highly diverse monomers and is capable of generating extensive compound libraries. Recent studies are beginning to explore the relationship between peptoid sequence, structure and function. We describe new approaches to direct the conformation of the peptoid backbone, leading to secondary structures such as helices, loops, and turns. These advances are enabling the discovery of bioactive peptoids and will establish modules for the design and assembly of protein mimetics.

Modelling of Sediment Transport of the Mehadica River, Caras Severin County, Romania

NASA Astrophysics Data System (ADS)

Grozav, Adia; Beilicci, Robert; Beilicci, Erika

2017-10-01

Study case is situated in Caras-Severin County. Every sediment transport model application is different both in terms of time and space scale, study objectives, required accuracy, allocated resources, background of the study team etc. For sediment transport modelling, it is necessary to know the characteristics of the sediment in the river bed. Therefore, it is recommended to collect a number of bed sediment grap samples. These samples should be analysing in terms of grain size distribution. To solve theoretical problems of movement of water in the river Mehadica, it requires modelling of water flow in this case. Numerical modelling was performed using the program MIKE11. MIKE 11 is a user-friendly, fully dynamic, one-dimensional modelling tool for the detailed analysis, design, management and operation of both simple and complex river and channel systems. With its exceptional flexibility, speed and user friendly environment, MIKE 11 provides a complete and effective design environment for engineering, water resources, water quality management and planning applications. The Hydrodynamic (HD) module is the nucleus of the MIKE 11 modelling system and forms the basis for most modules including Flood Forecasting, Advection- Dispersion, Water Quality and Non-cohesive sediment transport modules. The MIKE 11 HD module solves the vertically integrated equations for the conservation of mass and momentum, i.e. the Saint-Venant equations. The input data are: area plan with location of cross sections; cross sections topographical data and roughness of river bed; flood discharge hydrograph. Advanced computational modules are included for description of flow over hydraulic structures, including possibilities to describe structure operation.

Project T.E.A.M. (Technical Education Advancement Modules). Introduction to Industrial Physics.

ERIC Educational Resources Information Center

Whisenhunt, James E.

This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 20-hour introduction to industrial physics that explains and demonstrates to industrial maintenance mechanics the direct relationship of physics to machinery. Project TEAM is intended to upgrade basic technical competencies of…

Advanced Experiments in Nuclear Science, Volume I: Advanced Nuclear Physics and Chemistry Experiments.

ERIC Educational Resources Information Center

Duggan, Jerome L.; And Others

The experiments in this manual represent state-of-the-art techniques which should be within the budgetary constraints of a college physics or chemistry department. There are fourteen experiments divided into five modules. The modules are on X-ray fluorescence, charged particle detection, neutron activation analysis, X-ray attenuation, and…

Description of the L1C signal

USGS Publications Warehouse

Betz, J.W.; Blanco, M.A.; Cahn, C.R.; Dafesh, P.A.; Hegarty, C.J.; Hudnut, K.W.; Kasemsri, V.; Keegan, R.; Kovach, K.; Lenahan, L.S.; Ma, H.H.; Rushanan, J.J.; Sklar, D.; Stansell, T.A.; Wang, C.C.; Yi, S.K.

2006-01-01

Detailed design of the modernized LI civil signal (L1C) signal has been completed, and the resulting draft Interface Specification IS-GPS-800 was released in Spring 2006. The novel characteristics of the optimized L1C signal design provide advanced capabilities while offering to receiver designers considerable flexibility in how to use these capabilities. L1C provides a number of advanced features, including: 75% of power in a pilot component for enhanced signal tracking, advanced Weilbased spreading codes, an overlay code on the pilot that provides data message synchronization, support for improved reading of clock and ephemeris by combining message symbols across messages, advanced forward error control coding, and data symbol interleaving to combat fading. The resulting design offers receiver designers the opportunity to obtain unmatched performance in many ways. This paper describes the design of L1C. A summary of LIC's background and history is provided. The signal description then proceeds with the overall signal structure consisting of a pilot component and a carrier component. The new L1C spreading code family is described, along with the logic used for generating these spreading codes. Overlay codes on the pilot channel are also described, as is the logic used for generating the overlay codes. Spreading modulation characteristics are summarized. The data message structure is also presented, showing the format for providing time, ephemeris, and system data to users, along with features that enable receivers to perform code combining. Encoding of rapidly changing time bits is described, as are the Low Density Parity Check codes used for forward error control of slowly changing time bits, clock, ephemeris, and system data. The structure of the interleaver is also presented. A summary of L 1C's unique features and their benefits is provided, along with a discussion of the plan for L1C implementation.

Apollo Lightcraft Project

NASA Technical Reports Server (NTRS)

Myrabo, Leik N.; Smith, Wayne L. (Editor); Decusatis, Casimer; Frazier, Scott R.; Garrison, James L., Jr.; Meltzer, Jonathan S.; Minucci, Marco A.; Moder, Jeffrey P.; Morales, Ciro; Mueller, Mark T.

1988-01-01

This second year of the NASA/USRA-sponsored Advanced Aeronautical Design effort focused on systems integration and analysis of the Apollo Lightcraft. This beam-powered, single-stage-to-orbit vehicle is envisioned as the shuttlecraft of the 21st century. The five person vehicle was inspired largely by the Apollo Command Module, then reconfigured to include a new front seat with dual cockpit controls for the pilot and co-pilot, while still retaining the 3-abreast crew accommodations in the rear seat. The gross liftoff mass is 5550 kg, of which 500 kg is the payload and 300 kg is the LH2 propellant. The round trip cost to orbit is projected to be three orders of magnitude lower than the current space shuttle orbiter. The advanced laser-driven 5-speed combined-cycle engine has shiftpoints at Mach 1, 5, 11 and 25+. The Apollo Lightcraft can climb into low Earth orbit in three minutes, or fly to any spot on the globe in less than 45 minutes. Detailed investigations of the Apollo Lightcraft Project this second year further evolved the propulsion system design, while focusing on the following areas: (1) man/machine interface; (2) flight control systems; (3) power beaming system architecture; (4) re-entry aerodynamics; (5) shroud structural dynamics; and (6) optimal trajectory analysis. The principal new findings are documented. Advanced design efforts for the next academic year (1988/1989) will center on a one meter+ diameter spacecraft: the Lightcraft Technology Demonstrator (LTD). Detailed engineering design and analyses, as well as critical proof-of-concept experiments, will be carried out on this small, near-term machine. As presently conceived, the LTD could be constructed using state of the art components derived from existing liquid chemical rocket engine technology, advanced composite materials, and high power laser optics.

Charge Carriers Modulate the Bonding of Semiconductor Nanoparticle Dopants As Revealed by Time-Resolved X-ray Spectroscopy

DOE PAGES

Hassan, Asra; Zhang, Xiaoyi; Liu, Xiaohan; ...

2017-08-28

Understanding the electronic structure of doped semiconductors is essential to realize advancements in electronics and in the rational design of nanoscale devices. Here, we report the results of time-resolved X-ray absorption studies on copper-doped cadmium sulfide nanoparticles that provide an explicit description of the electronic dynamics of the dopants. The interaction of a dopant ion and an excess charge carrier is unambiguously observed via monitoring the oxidation state. The experimental data combined with DFT calculations demonstrate that dopant bonding to the host matrix is modulated by its interaction with charge carriers. Additionally, the transient photoluminescence and the kinetics of dopantmore » oxidation reveal the presence of two types of surface-bound ions that create mid-gap states.« less

3D-printed phase waveplates for THz beam shaping

NASA Astrophysics Data System (ADS)

Gospodaric, J.; Kuzmenko, A.; Pimenov, Anna; Huber, C.; Suess, D.; Rotter, S.; Pimenov, A.

2018-05-01

The advancement of 3D-printing opens up a new way of constructing affordable custom terahertz (THz) components due to suitable printing resolution and THz transparency of polymer materials. We present a way of calculating, designing, and fabricating a THz waveplate that phase-modulates an incident THz beam (λ0 = 2.14 mm) in order to create a predefined intensity profile of the optical wavefront on a distant image plane. Our calculations were performed for two distinct target intensities with the use of a modified Gerchberg-Saxton algorithm. The resulting phase-modulating profiles were used to model the polylactide elements, which were printed out with a commercially available 3D-printer. The results were tested in a THz experimental setup equipped with a scanning option, and they showed good agreement with theoretical predictions.

Aeromechanical stability analysis of COPTER

NASA Technical Reports Server (NTRS)

Yin, Sheng K.; Yen, Jing G.

1988-01-01

A plan was formed for developing a comprehensive, second-generation system with analytical capabilities for predicting performance, loads and vibration, handling qualities, aeromechanical stability, and acoustics. This second-generation system named COPTER (COmprehensive Program for Theoretical Evaluation of Rotorcraft) is designed for operational efficiency, user friendliness, coding readability, maintainability, transportability, modularity, and expandability for future growth. The system is divided into an executive, a data deck validator, and a technology complex. At present a simple executive, the data deck validator, and the aeromechanical stability module of the technology complex were implemented. The system is described briefly, the implementation of the technology module is discussed, and correlation data presented. The correlation includes hingeless-rotor isolated stability, hingeless-rotor ground-resonance stability, and air-resonance stability of an advanced bearingless-rotor in forward flight.

Advanced development of a programmable power processor

NASA Technical Reports Server (NTRS)

Lukens, F. E.; Lanier, J. R., Jr.; Kapustka, R. E.; Graves, J.

1980-01-01

The need for the development of a multipurpose flexible programmable power processor (PPP) has increased significantly in recent years to reduce ever rising development costs. One of the program requirements the PPP specification will cover is the 25 kW power module power conversion needs. The 25 kW power module could support the Space Shuttle program during the 1980s and 1990s and could be the stepping stone to future large space programs. Trades that led to selection of a microprocessor controlled power processor are briefly discussed. Emphasis is given to the power processing equipment that uses a microprocessor to provide versatility that allows multiple use and to provide for future growth by reprogramming output voltage to a higher level (to 120 V from 30 V). Component selection and design considerations are also discussed.

Obesity Pharmacotherapy: Current Perspectives and Future Directions

PubMed Central

Misra, Monika

2013-01-01

The rising tide of obesity and its related disorders is one of the most pressing health concerns worldwide, yet existing medicines to combat the problem are disappointingly limited in number and effectiveness. Recent advances in mechanistic insights into the neuroendocrine regulation of body weight have revealed an expanding list of molecular targets for novel, rationally designed antiobesity pharmaceutical agents. Antiobesity drugs act via any of four mechanisms: 1) decreasing energy intake, 2) increasing energy expenditure or modulating lipid metabolism, 3) modulating fat stores or adipocyte differentiation, and 4) mimicking caloric restriction. Various novel drug candidates and targets directed against obesity are currently being explored. A few of them are also in the later phases of clinical trials. This review discusses the development of novel antiobesity drugs based on current understanding of energy homeostasis PMID:23092275

Charge Carriers Modulate the Bonding of Semiconductor Nanoparticle Dopants As Revealed by Time-Resolved X-ray Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hassan, Asra; Zhang, Xiaoyi; Liu, Xiaohan

Understanding the electronic structure of doped semiconductors is essential to realize advancements in electronics and in the rational design of nanoscale devices. Here, we report the results of time-resolved X-ray absorption studies on copper-doped cadmium sulfide nanoparticles that provide an explicit description of the electronic dynamics of the dopants. The interaction of a dopant ion and an excess charge carrier is unambiguously observed via monitoring the oxidation state. The experimental data combined with DFT calculations demonstrate that dopant bonding to the host matrix is modulated by its interaction with charge carriers. Additionally, the transient photoluminescence and the kinetics of dopantmore » oxidation reveal the presence of two types of surface-bound ions that create mid-gap states.« less

Advanced study of video signal processing in low signal to noise environments

NASA Technical Reports Server (NTRS)

Carden, F.; Henry, R.

1972-01-01

A nonlinear analysis of a multifilter phase-lockloop (MPLL) by using the method of harmonic balance is presented. The particular MPLL considered has a low-pass filter and a band-pass filter in parallel. An analytic expression for the relationship between the input signal phase deviation and the phase error is determined for sinusoidal FM in the absence of noise. The expression is used to determine bounds on the proper operating region for the MPLL and to investigate the jump phenomenon previously observed. From these results the proper modulation index, modulating frequency, etc. used for the design of a MPLL are determined. Data for the loop unlock boundary obtained from the theoretical expression are compared to data obtained from analog computer simulations of the MPLL.

Dual-tasks and walking fast: relationship to extra-pyramidal signs in advanced Alzheimer disease.

PubMed

Camicioli, Richard; Bouchard, Thomas; Licis, Lisa

2006-10-25

Extra-pyramidal signs (EPS) and cadence predicted falls risk in patients with advanced Alzheimer disease (AD). Dual task performance predicts falls with variable success. Dual-task performance and walking fast were examined in advanced AD patients with EPS (EPS+, >3 modified Unified Parkinson's Disease Rating Scale [UPDRS] signs) or without EPS (EPS-, three or less UPDRS signs). Demographics, mental and functional status, behavioral impairment, EPS, and quantitative gait measures (GaitRite) were determined. The effects of an automatic dual-task (simple counting) and of walking fast on spatial and temporal gait characteristics were compared between EPS+ and EPS- subjects using a repeated measures design. Cadence decreased, while stride time, swing time and variability in swing time increased with the dual task. Results were insignificant after adjusting for secondary task performance. With walking fast, speed, cadence and stride length increased while stride time, swing time and double support time decreased. Although EPS+ subjects were slower and had decreased stride length, dual task and walking fast effects did not differ from EPS- subjects. Patient characteristics, the type of secondary task and the specific gait measures examined vary in the literature. In this moderately to severely demented population, EPS did not affect "unconscious" (dual task) or "conscious" (walking fast) gait modulation. Given their high falls risk, and retained ability to modulate walking, EPS+ AD patients may be ideal candidates for interventions aimed at preventing falls.

Development of a 150-GHz MMIC Module Prototype for Large-Scale CMB Radiation

NASA Technical Reports Server (NTRS)

Kangaslahti, Pekka P.; Samoska, Lorene A.; Gaier, Todd C.; Soria, Mary M.; Lau, Judy M.; Sieth, Matthew M.; VanWinkle, Daniel; Tantawi, Sami

2011-01-01

HEMT-based receiver arrays with excellent noise and scalability are already starting to be manufactured at 100 GHz, but the advances in technology should make it possible to develop receiver modules with even greater operation frequency up to 200 GHz. A prototype heterodyne amplifier module has been developed for operation from 140 to 170 GHz using monolithic millimeter-wave integrated circuit (MMIC) low-noise InP high electron mobility transistor (HEMT) amplifiers. The compact, scalable module is centered on the 150-GHz atmospheric window using components known to operate well at these frequencies. Arrays equipped with hundreds of these modules can be optimized for many different astrophysical measurement techniques, including spectroscopy and interferometry. This module is a heterodyne receiver module that is extremely compact, and makes use of 35-nm InP HEMT technology, and which has been shown to have excellent noise temperatures when cooled cryogenically to 30 K. This reduction in system noise over prior art has been demonstrated in commercial mixers (uncooled) at frequencies of 160-180 GHz. The module is expected to achieve a system noise temperature of 60 K when cooled. An MMIC amplifier module has been designed to demonstrate the feasibility of expanding heterodyne amplifier technology to the 140 to 170-GHz frequency range for astronomical observations. The miniaturization of many standard components and the refinement of RF interconnect technology have cleared the way to mass-production of heterodyne amplifier receivers, making it a feasible technology for many large-population arrays. This work furthers the recent research efforts in compact coherent receiver modules, including the development of the Q/U Imaging ExperimenT (QUIET) modules centered at 40 and 90 GHz, and the production of heterodyne module prototypes at 90 GHz.

Modulation and coding for satellite and space communications

NASA Technical Reports Server (NTRS)

Yuen, Joseph H.; Simon, Marvin K.; Pollara, Fabrizio; Divsalar, Dariush; Miller, Warner H.; Morakis, James C.; Ryan, Carl R.

1990-01-01

Several modulation and coding advances supported by NASA are summarized. To support long-constraint-length convolutional code, a VLSI maximum-likelihood decoder, utilizing parallel processing techniques, which is being developed to decode convolutional codes of constraint length 15 and a code rate as low as 1/6 is discussed. A VLSI high-speed 8-b Reed-Solomon decoder which is being developed for advanced tracking and data relay satellite (ATDRS) applications is discussed. A 300-Mb/s modem with continuous phase modulation (CPM) and codings which is being developed for ATDRS is discussed. Trellis-coded modulation (TCM) techniques are discussed for satellite-based mobile communication applications.

Non-Flow Through Fuel Cell Power Module Demonstration on the SCARAB Rover

NASA Technical Reports Server (NTRS)

Jakupca, Ian; Guzik, Monica; Bennett, William R.; Edwards, Lawrence

2017-01-01

NASA demonstrated the Advanced Product Water Removal (APWR) Non-Flow-Through (NFT) PEM fuel cell technology by powering the Scarab rover over three-(3) days of field operations. The latest generation APWR NFT fuel cell stackwas packaged by the Advanced Exploration Systems (AES) Modular Power Systems (AMPS) team into a nominallyrated 1-kW fuel cell power module. This power module was functionally verified in a laboratory prior to field operations on the Scarab rover, which concluded on 2 September 2015. During this demonstration, the power module satisfied all required success criteria by supporting all electrical loads as the Scarab navigated the NASA Glenn Research Center.

Analysis and Preliminary Design of an Advanced Technology Transport Flight Control System

NASA Technical Reports Server (NTRS)

Frazzini, R.; Vaughn, D.

1975-01-01

The analysis and preliminary design of an advanced technology transport aircraft flight control system using avionics and flight control concepts appropriate to the 1980-1985 time period are discussed. Specifically, the techniques and requirements of the flight control system were established, a number of candidate configurations were defined, and an evaluation of these configurations was performed to establish a recommended approach. Candidate configurations based on redundant integration of various sensor types, computational methods, servo actuator arrangements and data-transfer techniques were defined to the functional module and piece-part level. Life-cycle costs, for the flight control configurations, as determined in an operational environment model for 200 aircraft over a 15-year service life, were the basis of the optimum configuration selection tradeoff. The recommended system concept is a quad digital computer configuration utilizing a small microprocessor for input/output control, a hexad skewed set of conventional sensors for body rate and body acceleration, and triple integrated actuators.

Ares First Stage "Systemology" - Combining Advanced Systems Engineering and Planning Tools to Assure Mission Success

NASA Technical Reports Server (NTRS)

Seiler, James; Brasfield, Fred; Cannon, Scott

2008-01-01

Ares is an integral part of NASA s Constellation architecture that will provide crew and cargo access to the International Space Station as well as low earth orbit support for lunar missions. Ares replaces the Space Shuttle in the post 2010 time frame. Ares I is an in-line, two-stage rocket topped by the Orion Crew Exploration Vehicle, its service module, and a launch abort system. The Ares I first stage is a single, five-segment reusable solid rocket booster derived from the Space Shuttle Program's reusable solid rocket motor. The Ares second or upper stage is propelled by a J-2X main engine fueled with liquid oxygen and liquid hydrogen. This paper describes the advanced systems engineering and planning tools being utilized for the design, test, and qualification of the Ares I first stage element. Included are descriptions of the current first stage design, the milestone schedule requirements, and the marriage of systems engineering, detailed planning efforts, and roadmapping employed to achieve these goals.

Recent advances in radiation cancer therapy

NASA Astrophysics Data System (ADS)

Ma, C.-M. Charlie

2007-03-01

This paper presents the recent advances in radiation therapy techniques for the treatment of cancer. Significant improvement has been made in imaging techniques such as CT, MRI, MRS, PET, ultrasound, etc. that have brought marked advances in tumor target and critical structure delineation for treatment planning and patient setup and target localization for accurate dose delivery in radiation therapy of cancer. Recent developments of novel treatment modalities including intensity-modulated x-ray therapy (IMXT), energy- and intensity modulated electron therapy (MERT) and intensity modulated proton therapy (IMPT) together with the use of advanced image guidance have enabled precise dose delivery for dose escalation and hypofractionation studies that may result in better local control and quality of life. Particle acceleration using laser-induced plasmas has great potential for new cost-effective radiation sources that may have a great impact on the management of cancer using radiation therapy.

Selective Glucocorticoid Receptor modulators.

PubMed

De Bosscher, Karolien

2010-05-31

The ancient two-faced Roman god Janus is often used as a metaphor to describe the characteristics of the Glucocorticoid Receptor (NR3C1), which exhibits both a beneficial side, that serves to halt inflammation, and a detrimental side responsible for undesirable effects. However, recent developments suggest that the Glucocorticoid Receptor has many more faces with the potential to express a range of different functionalities, depending on factors that include the tissue type, ligand type, receptor variants, cofactor surroundings and target gene promoters. This behavior of the receptor has made the development of safer ligands, that trigger the expression program of only a desirable subset of genes, a real challenge. Thus more knowledge-based fundamental research is needed to ensure the design and development of selective Glucocorticoid Receptor modulators capable of reaching the clinic. Recent advances in the characterization of novel selective Glucocorticoid Receptor modulators, specifically in the context of anti-inflammatory strategies, will be described in this review. 2010 Elsevier Ltd. All rights reserved.

Design of real-time encryption module for secure data protection of wearable healthcare devices.

PubMed

Kim, Jungchae; Lee, Byuck Jin; Yoo, Sun K

2013-01-01

Wearable devices for biomedical instrumentation could generate the medical data and transmit to a repository on cloud service through wireless networks. In this process, the private medical data will be disclosed by man in the middle attack. Thus, the archived data for healthcare services would be protected by non-standardized security policy by healthcare service provider (HSP) because HIPAA only defines the security rules. In this paper, we adopted the Advanced Encryption Standard (AES) for security framework on wearable devices, so healthcare applications using this framework could support the confidentiality easily. The framework developed as dynamic loadable module targeted for lightweight microcontroller such as msp430 within embedded operating system. The performance was shown that the module can support the real-time encryption using electrocardiogram and photoplethysmogram. In this regard, the processing load for enabling security is distributed to wearable devices, and the customized data protection method could be composed by HSP for a trusted healthcare service.

Optical mass memory investigation

NASA Technical Reports Server (NTRS)

1980-01-01

The MASTER 1 optical mass storage system advanced working model (AWM) was designed to demonstrate recording and playback of imagery data and to enable quantitative data to be derived as to the statistical distribution of raw errors experienced through the system. The AWM consists of two subsystems, the recorder and storage and retrieval. The recorder subsystem utilizes key technologies such as an acoustic travelling wave lens to achieve recording of digital data on fiche at a rate of 30 Mbits/sec, whereas the storage and retrieval reproducer subsystem utilizes a less complex optical system that employs an acousto-optical beam deflector to achieve data readout at a 5 Mbits/sec rate. The system has the built in capability for detecting and collecting error statistics. The recorder and storage and retrieval subsystems operate independent of one another and are each constructed in modular form with each module performing independent functions. The operation of each module and its interface to other modules is controlled by one controller for both subsystems.

Note: Optics design of a periscope for the KSTAR visible inspection system with mitigated neutron damages on the camera

NASA Astrophysics Data System (ADS)

Lee, Kyuhang; Ko, Jinseok; Wi, Hanmin; Chung, Jinil; Seo, Hyeonjin; Jo, Jae Heung

2018-06-01

The visible TV system used in the Korea Superconducting Tokamak Advanced Research device has been equipped with a periscope to minimize the damage on its CCD pixels from neutron radiation. The periscope with more than 2.3 m in overall length has been designed for the visible camera system with its semi-diagonal field of view as wide as 30° and its effective focal length as short as 5.57 mm. The design performance of the periscope includes the modulation transfer function greater than 0.25 at 68 cycles/mm with low distortion. The installed periscope system has confirmed the image qualities as designed and also as comparable as those from its predecessor but with far less probabilities of neutral damages on the camera.

Process of constructing a lightweight x-ray flight mirror assembly

NASA Astrophysics Data System (ADS)

McClelland, Ryan S.; Biskach, Michael P.; Chan, Kai-Wing; Espina, Rebecca A.; Hohl, Bruce R.; Saha, Timo T.; Zhang, William W.

2014-07-01

Lightweight and high resolution optics are needed for future space-based x-ray telescopes to achieve advances in highenergy astrophysics. NASA's Next Generation X-ray Optics (NGXO) project has made significant progress towards building such optics, both in terms of maturing the technology for spaceflight readiness and improving the angular resolution. Technology Development Modules (TDMs) holding three pairs of mirrors have been regularly and repeatedly integrated and tested both for optical performance and mechanical strength. X-ray test results have been improved over the past year from 10.3 arc-seconds Half Power Diameter (HPD) to 8.3 arc-seconds HPD. A vibration test has been completed to NASA standard verification levels showing the optics can survive launch and pointing towards improvements in strengthening the modules through redundant bonds. A Finite Element Analysis (FEA) study was completed which shows the mirror distortion caused by bonding is insensitive to the number of bonds. Next generation TDMs, which will demonstrate a lightweight structure and mount additional pairs of mirrors, have been designed and fabricated. The light weight of the module structure is achieved through the use of E-60 Beryllium Oxide metal matrix composite material. As the angular resolution of the development modules has improved, gravity distortion during horizontal x-ray testing has become a limiting factor. To address this issue, a facility capable of testing in the vertical orientation has been designed and planned. Test boring at the construction site suggest standard caisson construction methods can be utilized to install a subterranean vertical vacuum pipe. This facility will also allow for the testing of kinematically mounted mirror segments, which greatly reduces the effect of bonding displacements. A development platform demonstrating the feasibility of kinematically mounting mirror segments has been designed, fabricated, and successfully tested.

Designing degradable hydrogels for orthogonal control of cell microenvironments

PubMed Central

Kharkar, Prathamesh M.

2013-01-01

Degradable and cell-compatible hydrogels can be designed to mimic the physical and biochemical characteristics of native extracellular matrices and provide tunability of degradation rates and related properties under physiological conditions. Hence, such hydrogels are finding widespread application in many bioengineering fields, including controlled bioactive molecule delivery, cell encapsulation for controlled three-dimensional culture, and tissue engineering. Cellular processes, such as adhesion, proliferation, spreading, migration, and differentiation, can be controlled within degradable, cell-compatible hydrogels with temporal tuning of biochemical or biophysical cues, such as growth factor presentation or hydrogel stiffness. However, thoughtful selection of hydrogel base materials, formation chemistries, and degradable moieties is necessary to achieve the appropriate level of property control and desired cellular response. In this review, hydrogel design considerations and materials for hydrogel preparation, ranging from natural polymers to synthetic polymers, are overviewed. Recent advances in chemical and physical methods to crosslink hydrogels are highlighted, as well as recent developments in controlling hydrogel degradation rates and modes of degradation. Special attention is given to spatial or temporal presentation of various biochemical and biophysical cues to modulate cell response in static (i.e., non-degradable) or dynamic (i.e., degradable) microenvironments. This review provides insight into the design of new cell-compatible, degradable hydrogels to understand and modulate cellular processes for various biomedical applications. PMID:23609001

Design and implementation of modular home security system with short messaging system

NASA Astrophysics Data System (ADS)

Budijono, Santoso; Andrianto, Jeffri; Axis Novradin Noor, Muhammad

2014-03-01

Today we are living in 21st century where crime become increasing and everyone wants to secure they asset at their home. In that situation user must have system with advance technology so person do not worry when getting away from his home. It is therefore the purpose of this design to provide home security device, which send fast information to user GSM (Global System for Mobile) mobile device using SMS (Short Messaging System) and also activate - deactivate system by SMS. The Modular design of this Home Security System make expandable their capability by add more sensors on that system. Hardware of this system has been designed using microcontroller AT Mega 328, PIR (Passive Infra Red) motion sensor as the primary sensor for motion detection, camera for capturing images, GSM module for sending and receiving SMS and buzzer for alarm. For software this system using Arduino IDE for Arduino and Putty for testing connection programming in GSM module. This Home Security System can monitor home area that surrounding by PIR sensor and sending SMS, save images capture by camera, and make people panic by turn on the buzzer when trespassing surrounding area that detected by PIR sensor. The Modular Home Security System has been tested and succeed detect human movement.

[Design and analysis of a novel light visible spectrum imaging spectrograph optical system].

PubMed

Shen, Man-de; Li, Fei; Zhou, Li-bing; Li, Cheng; Ren, Huan-huan; Jiang, Qing-xiu

2015-02-01

A novel visible spectrum imaging spectrograph optical system was proposed based on the negative dispersion, the arbitrary phase modulation characteristics of diffractive optical element and the aberration correction characteristics of freeform optical element. The double agglutination lens was substituted by a hybrid refractive/diffractive lens based on the negative dispersion of diffractive optical element. Two freeform optical elements were used in order to correct some aberration based on the aberration correction characteristics of freeform optical element. An example and frondose design process were presented. When the design parameters were uniform, compared with the traditional system, the novel visible spectrum imaging spectrograph optical system's weight was reduced by 22.9%, the total length was reduced by 26.6%, the maximal diameter was reduced by 30.6%, and the modulation transfer function (MTF) in 1.0 field-of-view was improved by 0.35 with field-of-view improved maximally. The maximal distortion was reduced by 1.6%, the maximal longitudinal aberration was reduced by 56.4%, and the lateral color aberration was reduced by 59. 3%. From these data, we know that the performance of the novel system was advanced quickly and it could be used to put forward a new idea for modern visible spectrum imaging spectrograph optical system design.

Research on ARM Numerical Control System

NASA Astrophysics Data System (ADS)

Wei, Xu; JiHong, Chen

Computerized Numerical Control (CNC) machine tools is the foundation of modern manufacturing systems, whose advanced digital technology is the key to solve the problem of sustainable development of machine tool manufacturing industry. The paper is to design CNC system embedded on ARM and indicates the hardware design and the software systems supported. On the hardware side: the driving chip of the motor control unit, as the core of components, is MCX314AL of DSP motion control which is developed by NOVA Electronics Co., Ltd. of Japan. It make convenient to control machine because of its excellent performance, simple interface, easy programming. On the Software side, the uC/OS-2 is selected as the embedded operating system of the open source, which makes a detailed breakdown of the modules of the CNC system. Those priorities are designed according to their actual requirements. The ways of communication between the module and the interrupt response are so different that it guarantees real-time property and reliability of the numerical control system. Therefore, it not only meets the requirements of the current social precision machining, but has good man-machine interface and network support to facilitate a variety of craftsmen use.

Nitrogen supply system based on hydrazine dissociation

NASA Technical Reports Server (NTRS)

Heppner, D. B.; Quattrone, P. D.

1981-01-01

Future long-duration manned space missions will require a method of generating N2 for cabin leakage makeup and repressurization. Life Systems, working with NASA, is developing a Nitrogen Supply Subsystem (NSS) based on the dissociation of N2H4 into a mixture of H2 and N2. The latter is separated to provide the makeup N2. Recent advances in specific hardware developments have resulted in the design and fabrication of a nominal 3.6 kg/day N2 generation module. The design integrates a N2H4 catalytic dissociator, three ammonia (NH3) dissociation stages and four H2 separation stages into a 33 kg, 14 cu dm module. A technique has been devised to alternate the NH3 dissociation and H2 separation stages to give high N2 purity in the product stream. Tests have shown the product stream to contain less than 0.5 percent H2 and 20 ppm NH3. This paper discusses the development and test activities of the NSS program. It reviews the design, configuration, operation and projected performance characteristics of a 4.4 kg/day NSS suitable for NASA's planned Space Operations Center.

OCGen Module Mooring Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

McEntee, Jarlath

Ocean Renewable Power Company's OCGen Module Mooring Project provided an extensive research, design, development, testing and data collection effort and analysis conducted with respect to a positively buoyant, submerged MHK device secured to the seabed using a tensioned mooring system. Different analytic tools were evaluated for their utility in the design of submerged systems and their moorings. Deployment and testing of a prototype OCGen® system provided significant data related to mooring line loads and system attitude and station keeping. Mooring line loads were measured in situ and reported against flow speeds. The Project made a significant step in the developmentmore » of designs, methodologies and practices related to floating and mooring of marine hydrokinetic (MHK) devices. Importantly for Ocean Renewable Power Company, the Project provided a sound basis for advancing a technically and commercially viable OCGen® Power System. The OCGen® Power System is unique in the MHK industry and, in itself, offers distinct advantages of MHK devices that are secured to the seabed using fixed structural frames. Foremost among these advantages are capital and operating cost reductions and increased power extraction by allowing the device to be placed at the most energetic level of the water column.« less

A Next Generation Digital Counting System For Low-Level Tritium Studies (Project Report)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowman, P.

2016-10-03

Since the early seventies, SRNL has pioneered low-level tritium analysis using various nuclear counting technologies and techniques. Since 1999, SRNL has successfully performed routine low-level tritium analyses with counting systems based on digital signal processor (DSP) modules developed in the late 1990s. Each of these counting systems are complex, unique to SRNL, and fully dedicated to performing routine tritium analyses of low-level environmental samples. It is time to modernize these systems due to a variety of issues including (1) age, (2) lack of direct replacement electronics modules and (3) advances in digital signal processing and computer technology. There has beenmore » considerable development in many areas associated with the enterprise of performing low-level tritium analyses. The objective of this LDRD project was to design, build, and demonstrate a Next Generation Tritium Counting System (NGTCS), while not disrupting the routine low-level tritium analyses underway in the facility on the legacy counting systems. The work involved (1) developing a test bed for building and testing new counting system hardware that does not interfere with our routine analyses, (2) testing a new counting system based on a modern state of the art DSP module, and (3) evolving the low-level tritium counter design to reflect the state of the science.« less

Simultaneous backward data transmission and power harvesting in an ultrasonic transcutaneous energy transfer link employing acoustically dependent electric impedance modulation.

PubMed

Ozeri, Shaul; Shmilovitz, Doron

2014-09-01

The advancement and miniaturization of body implanted medical devices pose several challenges to Ultrasonic Transcutaneous Energy Transfer (UTET), such as the need to reduce the size of the piezoelectric resonator, and the need to maximize the UTET link power-transfer efficiency. Accordingly, the same piezoelectric resonator that is used for energy harvesting at the body implant, may also be used for ultrasonic backward data transfer, for instance, through impedance modulation. This paper presents physical considerations and design guidelines of the body implanted transducer of a UTET link with impedance modulation for a backward data transfer. The acoustic matching design procedure was based on the 2×2 transfer matrix chain analysis, in addition to the Krimholtz Leedom and Matthaei KLM transmission line model. The UTET power transfer was carried out at a frequency of 765 kHz, continuous wave (CW) mode. The backward data transfer was attained by inserting a 9% load resistance variation around its matched value (550 Ohm), resulting in a 12% increase in the acoustic reflection coefficient. A backward data transmission rate of 1200 bits/s was experimentally demonstrated using amplitude shift keying, simultaneously with an acoustic power transfer of 20 mW to the implant. Copyright © 2014 Elsevier B.V. All rights reserved.

Using Health Communication Best Practices to Develop a Web-Based Provider-Patient Communication Aid: The CONNECT™ Study

PubMed Central

Fleisher, Linda; Buzaglo, Joanne; Collins, Michael; Millard, Jennifer; Miller, Suzanne M.; Egleston, Brian L.; Solarino, Nicholas; Trinastic, Jonathan; Cegala, Donald J.; Benson, Al B.; Schulman, Kevin A.; Weinfurt, Kevin P.; Sulmasy, Daniel; Diefenbach, Michael A.; Meropol, Neal J.

2008-01-01

Objective Although there is broad consensus that careful content vetting and user testing is important in the development of technology-based educational interventions, often these steps are overlooked. This paper highlights the development of a theory-guided, web-based communication aid (CONNECT™), designed to facilitate treatment decision making among patients with advanced cancer. Methods The communication aid included an online survey, patient skills training module and an automated physician report. Development steps included: 1) evidence-based content development, 2) usability testing, 3) pilot testing, and 4) patient utilization and satisfaction. Results Usability testing identified some confusing directions and navigation for the on-line survey and validated the relevance of the “patient testimonials” in the skills module. Preliminary satisfaction from the implementation of the communication aid showed that 66% found the survey length reasonable and 70% found it helpful in talking with the physician. Seventy percent reported the skills module helpful and about half found it affected the consultation. Conclusion Designing patient education interventions for translation into practice requires the integration of health communication best practice including user feedback along the developmental process. Practice Implications This developmental process can be translated to a broad array of community based patient and provider educational interventions. PMID:18417312

HDU Pressurized Excursion Module (PEM) Prototype Systems Integration

NASA Technical Reports Server (NTRS)

Gill, Tracy R.; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

2010-01-01

The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a skunk-works approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process included establishment of design standards, negotiation of interfaces between subsystems, and scheduling fit checks and installation activities. A major tool used in integration was a coordinated effort to accurately model all the subsystems using CAD, so that conflicts were identified before physical components came together. Some of the major conclusions showed that up-front modularity that emerged as an artifact of construction, such as the eight 45 degree "pie slices" making up the module whose steel rib edges defined structural mounting and loading points, dictated much of the configurational interfaces between the major subsystems and workstations. Therefore, 'one of the lessons learned included the need to use modularity as a tool for organization in advance, and to work harder to prevent non-critical aspects of the platform from dictating the modularity that may eventually inform the fight system.

Advances in polycrystalline thin-film photovoltaics for space applications

NASA Technical Reports Server (NTRS)

Lanning, Bruce R.; Armstrong, Joseph H.; Misra, Mohan S.

1994-01-01

Polycrystalline, thin-film photovoltaics represent one of the few (if not the only) renewable power sources which has the potential to satisfy the demanding technical requirements for future space applications. The demand in space is for deployable, flexible arrays with high power-to-weight ratios and long-term stability (15-20 years). In addition, there is also the demand that these arrays be produced by scalable, low-cost, high yield, processes. An approach to significantly reduce costs and increase reliability is to interconnect individual cells series via monolithic integration. Both CIS and CdTe semiconductor films are optimum absorber materials for thin-film n-p heterojunction solar cells, having band gaps between 0.9-1.5 ev and demonstrated small area efficiencies, with cadmium sulfide window layers, above 16.5 percent. Both CIS and CdTe polycrystalline thin-film cells have been produced on a laboratory scale by a variety of physical and chemical deposition methods, including evaporation, sputtering, and electrodeposition. Translating laboratory processes which yield these high efficiency, small area cells into the design of a manufacturing process capable of producing 1-sq ft modules, however, requires a quantitative understanding of each individual step in the process and its (each step) effect on overall module performance. With a proper quantification and understanding of material transport and reactivity for each individual step, manufacturing process can be designed that is not 'reactor-specific' and can be controlled intelligently with the design parameters of the process. The objective of this paper is to present an overview of the current efforts at MMC to develop large-scale manufacturing processes for both CIS and CdTe thin-film polycrystalline modules. CIS cells/modules are fabricated in a 'substrate configuration' by physical vapor deposition techniques and CdTe cells/modules are fabricated in a 'superstrate configuration' by wet chemical methods. Both laser and mechanical scribing operations are used to monolithically integrate (series interconnect) the individual cells into modules. Results will be presented at the cell and module development levels with a brief description of the test methods used to qualify these devices for space applications. The approach and development efforts are directed towards large-scale manufacturability of established thin-film, polycrystalline processing methods for large area modules with less emphasis on maximizing small area efficiencies.

The synergistic use of computation, chemistry and biology to discover novel peptide-based drugs: the time is right.

PubMed

Audie, J; Boyd, C

2010-01-01

The case for peptide-based drugs is compelling. Due to their chemical, physical and conformational diversity, and relatively unproblematic toxicity and immunogenicity, peptides represent excellent starting material for drug discovery. Nature has solved many physiological and pharmacological problems through the use of peptides, polypeptides and proteins. If nature could solve such a diversity of challenging biological problems through the use of peptides, it seems reasonable to infer that human ingenuity will prove even more successful. And this, indeed, appears to be the case, as a number of scientific and methodological advances are making peptides and peptide-based compounds ever more promising pharmacological agents. Chief among these advances are powerful chemical and biological screening technologies for lead identification and optimization, methods for enhancing peptide in vivo stability, bioavailability and cell-permeability, and new delivery technologies. Other advances include the development and experimental validation of robust computational methods for peptide lead identification and optimization. Finally, scientific analysis, biology and chemistry indicate the prospect of designing relatively small peptides to therapeutically modulate so-called 'undruggable' protein-protein interactions. Taken together a clear picture is emerging: through the synergistic use of the scientific imagination and the computational, chemical and biological methods that are currently available, effective peptide therapeutics for novel targets can be designed that surpass even the proven peptidic designs of nature.

Design Sketches For Optical Crossbar Switches Intended For Large-Scale Parallel Processing Applications

NASA Astrophysics Data System (ADS)

Hartmann, Alfred; Redfield, Steve

1989-04-01

This paper discusses design of large-scale (1000x 1000) optical crossbar switching networks for use in parallel processing supercom-puters. Alternative design sketches for an optical crossbar switching network are presented using free-space optical transmission with either a beam spreading/masking model or a beam steering model for internodal communications. The performances of alternative multiple access channel communications protocol-unslotted and slotted ALOHA and carrier sense multiple access (CSMA)-are compared with the performance of the classic arbitrated bus crossbar of conventional electronic parallel computing. These comparisons indicate an almost inverse relationship between ease of implementation and speed of operation. Practical issues of optical system design are addressed, and an optically addressed, composite spatial light modulator design is presented for fabrication to arbitrarily large scale. The wide range of switch architecture, communications protocol, optical systems design, device fabrication, and system performance problems presented by these design sketches poses a serious challenge to practical exploitation of highly parallel optical interconnects in advanced computer designs.

Fully integrated sub 100ps photon counting platform

NASA Astrophysics Data System (ADS)

Buckley, S. J.; Bellis, S. J.; Rosinger, P.; Jackson, J. C.

2007-02-01

Current state of the art high resolution counting modules, specifically designed for high timing resolution applications, are largely based on a computer card format. This has tended to result in a costly solution that is restricted to the computer it resides in. We describe a four channel timing module that interfaces to a computer via a USB port and operates with a resolution of less than 100 picoseconds. The core design of the system is an advanced field programmable gate array (FPGA) interfacing to a precision time interval measurement module, mass memory block and a high speed USB 2.0 serial data port. The FPGA design allows the module to operate in a number of modes allowing both continuous recording of photon events (time-tagging) and repetitive time binning. In time-tag mode the system reports, for each photon event, the high resolution time along with the chronological time (macro time) and the channel ID. The time-tags are uploaded in real time to a host computer via a high speed USB port allowing continuous storage to computer memory of up to 4 millions photons per second. In time-bin mode, binning is carried out with count rates up to 10 million photons per second. Each curve resides in a block of 128,000 time-bins each with a resolution programmable down to less than 100 picoseconds. Each bin has a limit of 65535 hits allowing autonomous curve recording until a bin reaches the maximum count or the system is commanded to halt. Due to the large memory storage, several curves/experiments can be stored in the system prior to uploading to the host computer for analysis. This makes this module ideal for integration into high timing resolution specific applications such as laser ranging and fluorescence lifetime imaging using techniques such as time correlated single photon counting (TCSPC).

A compact self-flowing lithium system for use in an industrial neutron source

NASA Astrophysics Data System (ADS)

Kalathiparambil, Kishor Kumar; Szott, Matthew; Jurczyk, Brian; Ahn, Chisung; Ruzic, David

2016-10-01

A compact trench module to flow liquid lithium in closed loops for handling high heat and particle flux have been fabricated and tested at UIUC. The module was designed to demonstrate the proof of concept in utilizing liquid metals for two principal objectives: i) as self-healing low Z plasma facing components, which is expected to solve the issues facing the current high Z components and ii) using flowing lithium as an MeV-level neutron source. A continuously flowing lithium loop ensures a fresh lithium interface and also accommodate a higher concentration of D, enabling advanced D-Li reactions without using any radioactive tritium. Such a system is expected to have a base yield of 10e7 n/s. For both the applications, the key success factor of the module is attaining the necessary high flow velocity of the lithium especially over the impact area, which will be the disruptive plasma events in fusion reactors and the incident ion beam for the neutron beam source. This was achieved by the efficient shaping of the trenches to exploit the nozzle effect in liquid flow. The compactness of the module, which can also be scaled as desired, was fulfilled by the use of high Tc permanent magnets and air cooled channels attained the necessary temperature gradient for driving the lithium. The design considerations and parameters, experimental arrangements involving lithium filling and attaining flow, data and results obtained will be elaborated. DOE SBIR project DE-SC0013861.

Design, fabrication and test of block 4 design solar cell modules. Part 2: Residential module

NASA Technical Reports Server (NTRS)

Jester, T. L.

1982-01-01

Design, fabrication and test of the Block IV residential load module are reported. Design changes from the proposed module design through three iterations to the discontinuance of testing are outlined.

Development of Advanced Life Cycle Costing Methods for Technology Benefit/Cost/Risk Assessment

NASA Technical Reports Server (NTRS)

Yackovetsky, Robert (Technical Monitor)

2002-01-01

The overall objective of this three-year grant is to provide NASA Langley's System Analysis Branch with improved affordability tools and methods based on probabilistic cost assessment techniques. In order to accomplish this objective, the Aerospace Systems Design Laboratory (ASDL) needs to pursue more detailed affordability, technology impact, and risk prediction methods and to demonstrate them on variety of advanced commercial transports. The affordability assessment, which is a cornerstone of ASDL methods, relies on the Aircraft Life Cycle Cost Analysis (ALCCA) program originally developed by NASA Ames Research Center and enhanced by ASDL. This grant proposed to improve ALCCA in support of the project objective by updating the research, design, test, and evaluation cost module, as well as the engine development cost module. Investigations into enhancements to ALCCA include improved engine development cost, process based costing, supportability cost, and system reliability with airline loss of revenue for system downtime. A probabilistic, stand-alone version of ALCCA/FLOPS will also be developed under this grant in order to capture the uncertainty involved in technology assessments. FLOPS (FLight Optimization System program) is an aircraft synthesis and sizing code developed by NASA Langley Research Center. This probabilistic version of the coupled program will be used within a Technology Impact Forecasting (TIF) method to determine what types of technologies would have to be infused in a system in order to meet customer requirements. A probabilistic analysis of the CER's (cost estimating relationships) within ALCCA will also be carried out under this contract in order to gain some insight as to the most influential costs and the impact that code fidelity could have on future RDS (Robust Design Simulation) studies.

Design, analysis, and test verification of advanced encapsulation systems

NASA Technical Reports Server (NTRS)

Mardesich, N.; Minning, C.

1982-01-01

Design sensitivities are established for the development of photovoltaic module criteria and the definition of needed research tasks. The program consists of three phases. In Phase I, analytical models were developed to perform optical, thermal, electrical, and structural analyses on candidate encapsulation systems. From these analyses several candidate systems will be selected for qualification testing during Phase II. Additionally, during Phase II, test specimens of various types will be constructed and tested to determine the validity of the analysis methodology developed in Phase I. In Phse III, a finalized optimum design based on knowledge gained in Phase I and II will be developed. All verification testing was completed during this period. Preliminary results and observations are discussed. Descriptions of the thermal, thermal structural, and structural deflection test setups are included.

Skylab electronic technological advancements

NASA Technical Reports Server (NTRS)

Hornback, G. L.

1974-01-01

The present work describes three electronic devices designed for use in the Skylab airlock module: the teleprinter system, the quartz crystal microbalance contamination monitor (QCM), and the speaker. Design considerations, operation, characteristics, and system development are described for these systems, with accompanying diagrams, graphs, and photographs. The teleprinter is a thermal dot printer used to produce hard copy messages by electrically heating print elements in contact with heat-sensitive paper. The QCM was designed to estimate contamination buildup on optical surfaces of the earth resources experiment package. A vibrating quartz crystal is used as a microbalance relating deposited mass to shifts in the crystal's resonant frequency. Audio devices provide communication between crew members and between crew and STDN, and also provide audible alarms, via the caution and warning system, of out-of-limit-conditions.

A Multi-Purpose Modular Electronics Integration Node for Exploration Extravehicular Activity

NASA Technical Reports Server (NTRS)

Hodgson, Edward; Papale, William; Wichowski, Robert; Rosenbush, David; Hawes, Kevin; Stankiewicz, Tom

2013-01-01

As NASA works to develop an effective integrated portable life support system design for exploration Extravehicular activity (EVA), alternatives to the current system s electrical power and control architecture are needed to support new requirements for flexibility, maintainability, reliability, and reduced mass and volume. Experience with the current Extravehicular Mobility Unit (EMU) has demonstrated that the current architecture, based in a central power supply, monitoring and control unit, with dedicated analog wiring harness connections to active components in the system has a significant impact on system packaging and seriously constrains design flexibility in adapting to component obsolescence and changing system needs over time. An alternative architecture based in the use of a digital data bus offers possible wiring harness and system power savings, but risks significant penalties in component complexity and cost. A hybrid architecture that relies on a set of electronic and power interface nodes serving functional models within the Portable Life Support System (PLSS) is proposed to minimize both packaging and component level penalties. A common interface node hardware design can further reduce penalties by reducing the nonrecurring development costs, making miniaturization more practical, maximizing opportunities for maturation and reliability growth, providing enhanced fault tolerance, and providing stable design interfaces for system components and a central control. Adaptation to varying specific module requirements can be achieved with modest changes in firmware code within the module. A preliminary design effort has developed a common set of hardware interface requirements and functional capabilities for such a node based on anticipated modules comprising an exploration PLSS, and a prototype node has been designed assembled, programmed, and tested. One instance of such a node has been adapted to support testing the swingbed carbon dioxide and humidity control element in NASA s advanced PLSS 2.0 test article. This paper will describe the common interface node design concept, results of the prototype development and test effort, and plans for use in NASA PLSS 2.0 integrated tests.

Interactive web-based learning modules prior to general medicine advanced pharmacy practice experiences.

PubMed

Isaacs, Alex N; Walton, Alison M; Nisly, Sarah A

2015-04-25

To implement and evaluate interactive web-based learning modules prior to advanced pharmacy practice experiences (APPEs) on inpatient general medicine. Three clinical web-based learning modules were developed for use prior to APPEs in 4 health care systems. The aim of the interactive modules was to strengthen baseline clinical knowledge before the APPE to enable the application of learned material through the delivery of patient care. For the primary endpoint, postassessment scores increased overall and for each individual module compared to preassessment scores. Postassessment scores were similar among the health care systems. The survey demonstrated positive student perceptions of this learning experience. Prior to inpatient general medicine APPEs, web-based learning enabled the standardization and assessment of baseline student knowledge across 4 health care systems.

Development of Advanced Seed Laser Modules for Lidar and Spectroscopy Applications

NASA Technical Reports Server (NTRS)

Prasad, Narasimha S.; Rosiewicz, Alex; Coleman, Steven M.

2013-01-01

We report on recent progress made in the development of highly compact, single mode, distributed feedback laser (DFB) seed laser modules for lidar and spectroscopy applications from space based platforms. One of the intended application of this technology is in the NASA's Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The DFB laser modules operating at 1571 nm and 1262 nm have advanced current and temperature drivers built into them. A combination of temperature and current tuning allows coarse and fine adjustment of the diode wavelengths.

Advanced Transport Operating System (ATOPS) control display unit software description

NASA Technical Reports Server (NTRS)

Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

1992-01-01

The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

Signal Acquisition Using AXIe

NASA Astrophysics Data System (ADS)

Narciso, Steven J.

2011-08-01

An emerging test and measurement standard called AXIe, AdvancedTCA extensions for Instrumentation, is expected to find wide acceptance within the Physics community as it offers many benefits to applications including shock, plasma, particle and nuclear physics. It is expected that many COTS (commercial off-the-shelf) signal conditioning, acquisition and processing modules will become available from a range of different suppliers. AXIe uses AdvancedTCA® as its basis, but then levers test and measurement industry standards such as PXI, IVI, and LXI to facilitate cooperation and plug-and-play interoperability between COTS instrument suppliers. AXIe's large board footprint and power allows high density in a 19" rack, enabling the development of high-performance signal conditioning, analog-to-digital conversion, and data processing, while offering channel count scalability inherent in modular systems. Synchronization between modules is flexible and provided by two triggering structures: a parallel trigger bus, and radially-distributed, time-matched point-to-point trigger lines. Inter-module communication is also provided with an adjacent module local bus allowing data transfer to 600 Gbits/s in each direction, for example between a front-end digitizer and DSP. AXIe allows embedding high performance computing and a range of COTS AdvancedTCA® computer blades are currently available that provide low cost alternatives to the development of custom signal processing modules. The availability of both LAN and PCI Express allow interconnection between modules, as well as industry-standard high-performance data paths to external host computer systems. AXIe delivers a powerful environment for custom module devel opment. As in the case of VXIbus and PXI before it, commercial development kits are expected to be available. This paper will give an overview of the architectural elements of AXIe 1.0, the compatibility model with AdvancedTCA, and signal acquisition performance of many of the AXIe structures.

The design and development of a rectangular, shingle-type photovoltaic module

NASA Astrophysics Data System (ADS)

Shepard, N. F., Jr.

A shingle-type photovoltaic module has been designed and developed to meet the requirements of specifications for residential applications. The module is ideally suited for installation directly to the sheathing of a sloping, south-facing roof of a residential, industrial, or commercial building. The design requirements are examined, taking into account also module safety requirements. Aspects of module design and analysis are discussed, giving attention to installation details, solar cells and electrical circuit design, the encapsulation system, substrate lamination, and the module-to-module interconnecting cable. Details of module assembly experience and test and outdoor exposure experience are also considered.

The design and development of a rectangular, shingle-type photovoltaic module

NASA Technical Reports Server (NTRS)

Shepard, N. F., Jr.

1982-01-01

A shingle-type photovoltaic module has been designed and developed to meet the requirements of specifications for residential applications. The module is ideally suited for installation directly to the sheathing of a sloping, south-facing roof of a residential, industrial, or commercial building. The design requirements are examined, taking into account also module safety requirements. Aspects of module design and analysis are discussed, giving attention to installation details, solar cells and electrical circuit design, the encapsulation system, substrate lamination, and the module-to-module interconnecting cable. Details of module assembly experience and test and outdoor exposure experience are also considered.

Messages, Meanings, and Minestrone: The Communication Cookbook.

ERIC Educational Resources Information Center

Gershwin, Mary Crabbe; And Others

One of a series of workplace education modules, this module includes activities and exercises for teaching communication skills in the workplace. First, introductory material reviews the goals of the module and defines three levels of difficulty of module activities (i.e., beginner, intermediate, and advanced). The importance of communication…

Design and experimental evaluation on an advanced multisource energy harvesting system for wireless sensor nodes.

PubMed

Li, Hao; Zhang, Gaofei; Ma, Rui; You, Zheng

2014-01-01

An effective multisource energy harvesting system is presented as power supply for wireless sensor nodes (WSNs). The advanced system contains not only an expandable power management module including control of the charging and discharging process of the lithium polymer battery but also an energy harvesting system using the maximum power point tracking (MPPT) circuit with analog driving scheme for the collection of both solar and vibration energy sources. Since the MPPT and the power management module are utilized, the system is able to effectively achieve a low power consumption. Furthermore, a super capacitor is integrated in the system so that current fluctuations of the lithium polymer battery during the charging and discharging processes can be properly reduced. In addition, through a simple analog switch circuit with low power consumption, the proposed system can successfully switch the power supply path according to the ambient energy sources and load power automatically. A practical WSNs platform shows that efficiency of the energy harvesting system can reach about 75-85% through the 24-hour environmental test, which confirms that the proposed system can be used as a long-term continuous power supply for WSNs.

Design and Experimental Evaluation on an Advanced Multisource Energy Harvesting System for Wireless Sensor Nodes

PubMed Central

Li, Hao; Zhang, Gaofei; Ma, Rui; You, Zheng

2014-01-01

An effective multisource energy harvesting system is presented as power supply for wireless sensor nodes (WSNs). The advanced system contains not only an expandable power management module including control of the charging and discharging process of the lithium polymer battery but also an energy harvesting system using the maximum power point tracking (MPPT) circuit with analog driving scheme for the collection of both solar and vibration energy sources. Since the MPPT and the power management module are utilized, the system is able to effectively achieve a low power consumption. Furthermore, a super capacitor is integrated in the system so that current fluctuations of the lithium polymer battery during the charging and discharging processes can be properly reduced. In addition, through a simple analog switch circuit with low power consumption, the proposed system can successfully switch the power supply path according to the ambient energy sources and load power automatically. A practical WSNs platform shows that efficiency of the energy harvesting system can reach about 75–85% through the 24-hour environmental test, which confirms that the proposed system can be used as a long-term continuous power supply for WSNs. PMID:25032233

SMMRNA: a database of small molecule modulators of RNA

PubMed Central

Mehta, Ankita; Sonam, Surabhi; Gouri, Isha; Loharch, Saurabh; Sharma, Deepak K.; Parkesh, Raman

2014-01-01

We have developed SMMRNA, an interactive database, available at http://www.smmrna.org, with special focus on small molecule ligands targeting RNA. Currently, SMMRNA consists of ∼770 unique ligands along with structural images of RNA molecules. Each ligand in the SMMRNA contains information such as Kd, Ki, IC50, ΔTm, molecular weight (MW), hydrogen donor and acceptor count, XlogP, number of rotatable bonds, number of aromatic rings and 2D and 3D structures. These parameters can be explored using text search, advanced search, substructure and similarity-based analysis tools that are embedded in SMMRNA. A structure editor is provided for 3D visualization of ligands. Advance analysis can be performed using substructure and OpenBabel-based chemical similarity fingerprints. Upload facility for both RNA and ligands is also provided. The physicochemical properties of the ligands were further examined using OpenBabel descriptors, hierarchical clustering, binning partition and multidimensional scaling. We have also generated a 3D conformation database of ligands to support the structure and ligand-based screening. SMMRNA provides comprehensive resource for further design, development and refinement of small molecule modulators for selective targeting of RNA molecules. PMID:24163098

Variable Conductance Heat Pipe Cooling of Stirling Convertor and General Purpose Heat Source

NASA Technical Reports Server (NTRS)

Tarau, Calin; Schwendeman, Carl; Anderson William G.; Cornell, Peggy A.; Schifer, Nicholas A.

2013-01-01

In a Stirling Radioisotope Power System (RPS), heat must be continuously removed from the General Purpose Heat Source (GPHS) modules to maintain the modules and surrounding insulation at acceptable temperatures. The Stirling convertor normally provides this cooling. If the Stirling convertor stops in the current system, the insulation is designed to spoil, preventing damage to the GPHS at the cost of an early termination of the mission. An alkali-metal Variable Conductance Heat Pipe (VCHP) can be used to passively allow multiple stops and restarts of the Stirling convertor. In a previous NASA SBIR Program, Advanced Cooling Technologies, Inc. (ACT) developed a series of sodium VCHPs as backup cooling systems for Stirling RPS. The operation of these VCHPs was demonstrated using Stirling heater head simulators and GPHS simulators. In the most recent effort, a sodium VCHP with a stainless steel envelope was designed, fabricated and tested at NASA Glenn Research Center (GRC) with a Stirling convertor for two concepts; one for the Advanced Stirling Radioisotope Generator (ASRG) back up cooling system and one for the Long-lived Venus Lander thermal management system. The VCHP is designed to activate and remove heat from the stopped convertor at a 19 degC temperature increase from the nominal vapor temperature. The 19 degC temperature increase from nominal is low enough to avoid risking standard ASRG operation and spoiling of the Multi-Layer Insulation (MLI). In addition, the same backup cooling system can be applied to the Stirling convertor used for the refrigeration system of the Long-lived Venus Lander. The VCHP will allow the refrigeration system to: 1) rest during transit at a lower temperature than nominal; 2) pre-cool the modules to an even lower temperature before the entry in Venus atmosphere; 3) work at nominal temperature on Venus surface; 4) briefly stop multiple times on the Venus surface to allow scientific measurements. This paper presents the experimental results from integrating the VCHP with an operating Stirling convertor and describes the methodology used to achieve their successful combined operation.

Alkali Metal Backup Cooling for Stirling Systems - Experimental Results

NASA Technical Reports Server (NTRS)

Schwendeman, Carl; Tarau, Calin; Anderson, William G.; Cornell, Peggy A.

2013-01-01

In a Stirling Radioisotope Power System (RPS), heat must be continuously removed from the General Purpose Heat Source (GPHS) modules to maintain the modules and surrounding insulation at acceptable temperatures. The Stirling convertor normally provides this cooling. If the Stirling convertor stops in the current system, the insulation is designed to spoil, preventing damage to the GPHS at the cost of an early termination of the mission. An alkali-metal Variable Conductance Heat Pipe (VCHP) can be used to passively allow multiple stops and restarts of the Stirling convertor. In a previous NASA SBIR Program, Advanced Cooling Technologies, Inc. (ACT) developed a series of sodium VCHPs as backup cooling systems for Stirling RPS. The operation of these VCHPs was demonstrated using Stirling heater head simulators and GPHS simulators. In the most recent effort, a sodium VCHP with a stainless steel envelope was designed, fabricated and tested at NASA Glenn Research Center (GRC) with a Stirling convertor for two concepts; one for the Advanced Stirling Radioisotope Generator (ASRG) back up cooling system and one for the Long-lived Venus Lander thermal management system. The VCHP is designed to activate and remove heat from the stopped convertor at a 19 C temperature increase from the nominal vapor temperature. The 19 C temperature increase from nominal is low enough to avoid risking standard ASRG operation and spoiling of the Multi-Layer Insulation (MLI). In addition, the same backup cooling system can be applied to the Stirling convertor used for the refrigeration system of the Long-lived Venus Lander. The VCHP will allow the refrigeration system to: 1) rest during transit at a lower temperature than nominal; 2) pre-cool the modules to an even lower temperature before the entry in Venus atmosphere; 3) work at nominal temperature on Venus surface; 4) briefly stop multiple times on the Venus surface to allow scientific measurements. This paper presents the experimental results from integrating the VCHP with an operating Stirling convertor and describes the methodology used to achieve their successful combined operation.

Alkali Metal Backup Cooling for Stirling Systems - Experimental Results

NASA Technical Reports Server (NTRS)

Schwendeman, Carl; Tarau, Calin; Anderson, William G.; Cornell, Peggy A.

2013-01-01

In a Stirling Radioisotope Power System (RPS), heat must be continuously removed from the General Purpose Heat Source (GPHS) modules to maintain the modules and surrounding insulation at acceptable temperatures. The Stirling convertor normally provides this cooling. If the Stirling convertor stops in the current system, the insulation is designed to spoil, preventing damage to the GPHS at the cost of an early termination of the mission. An alkali-metal Variable Conductance Heat Pipe (VCHP) can be used to passively allow multiple stops and restarts of the Stirling convertor. In a previous NASA SBIR Program, Advanced Cooling Technologies, Inc. (ACT) developed a series of sodium VCHPs as backup cooling systems for Stirling RPS. The operation of these VCHPs was demonstrated using Stirling heater head simulators and GPHS simulators. In the most recent effort, a sodium VCHP with a stainless steel envelope was designed, fabricated and tested at NASA Glenn Research Center (GRC) with a Stirling convertor for two concepts; one for the Advanced Stirling Radioisotope Generator (ASRG) back up cooling system and one for the Long-lived Venus Lander thermal management system. The VCHP is designed to activate and remove heat from the stopped convertor at a 19 degC temperature increase from the nominal vapor temperature. The 19 degC temperature increase from nominal is low enough to avoid risking standard ASRG operation and spoiling of the Multi-Layer Insulation (MLI). In addition, the same backup cooling system can be applied to the Stirling convertor used for the refrigeration system of the Long-lived Venus Lander. The VCHP will allow the refrigeration system to: 1) rest during transit at a lower temperature than nominal; 2) pre-cool the modules to an even lower temperature before the entry in Venus atmosphere; 3) work at nominal temperature on Venus surface; 4) briefly stop multiple times on the Venus surface to allow scientific measurements. This paper presents the experimental results from integrating the VCHP with an operating Stirling convertor and describes the methodology used to achieve their successful combined operation.

PVMaT 1998 overview

NASA Astrophysics Data System (ADS)

Mittchell, Richard L.; Symko-Davies, Martha; Thomas, Holly P.; Witt, C. Edwin

1999-03-01

The Photovoltaic Manufacturing Technology (PVMaT) Project is a government/industry research and development (R&D) partnership between the U.S. federal government (through the U.S. Department of Energy [DOE]) and members of the U.S. PV industry. The goals of PVMaT are to assist the U.S. PV industry improve module manufacturing processes and equipment; accelerate manufacturing cost reductions for PV modules, balance-of-systems components, and integrated systems; increase commercial product performance and reliability; and enhance investment opportunities for substantial scale-ups of U.S.-based PV manufacturing plant capacities. The approach for PVMaT has been to cost-share the R&D risk as industry explores new manufacturing options and ideas for improved PV modules and components, advances system and product integration, and develops new system designs. These activities will lead to overall reduced system life-cycle costs for reliable PV end-products. The 1994 PVMaT Product-Driven BOS and Systems activities, as well as Product-Driven Module Manufacturing R&D activities, are just being completed. Fourteen new subcontracts have just been awarded in the areas of PV System and Component Technology and Module Manufacturing Technology. Government funding, subcontractor cost-sharing, and a comparison of the relative efforts by PV technology throughout the PVMaT project are also discussed.

Accurate determination of segmented X-ray detector geometry

DOE PAGES

Yefanov, Oleksandr; Mariani, Valerio; Gati, Cornelius; ...

2015-10-22

Recent advances in X-ray detector technology have resulted in the introduction of segmented detectors composed of many small detector modules tiled together to cover a large detection area. Due to mechanical tolerances and the desire to be able to change the module layout to suit the needs of different experiments, the pixels on each module might not align perfectly on a regular grid. Several detectors are designed to permit detector sub-regions (or modules) to be moved relative to each other for different experiments. Accurate determination of the location of detector elements relative to the beam-sample interaction point is critical formore » many types of experiment, including X-ray crystallography, coherent diffractive imaging (CDI), small angle X-ray scattering (SAXS) and spectroscopy. For detectors with moveable modules, the relative positions of pixels are no longer fixed, necessitating the development of a simple procedure to calibrate detector geometry after reconfiguration. We describe a simple and robust method for determining the geometry of segmented X-ray detectors using measurements obtained by serial crystallography. By comparing the location of observed Bragg peaks to the spot locations predicted from the crystal indexing procedure, the position, rotation and distance of each module relative to the interaction region can be refined. Furthermore, we show that the refined detector geometry greatly improves the results of experiments.« less

Development of a Microsoft Excel tool for one-parameter Rasch model of continuous items: an application to a safety attitude survey.

PubMed

Chien, Tsair-Wei; Shao, Yang; Kuo, Shu-Chun

2017-01-10

Many continuous item responses (CIRs) are encountered in healthcare settings, but no one uses item response theory's (IRT) probabilistic modeling to present graphical presentations for interpreting CIR results. A computer module that is programmed to deal with CIRs is required. To present a computer module, validate it, and verify its usefulness in dealing with CIR data, and then to apply the model to real healthcare data in order to show how the CIR that can be applied to healthcare settings with an example regarding a safety attitude survey. Using Microsoft Excel VBA (Visual Basic for Applications), we designed a computer module that minimizes the residuals and calculates model's expected scores according to person responses across items. Rasch models based on a Wright map and on KIDMAP were demonstrated to interpret results of the safety attitude survey. The author-made CIR module yielded OUTFIT mean square (MNSQ) and person measures equivalent to those yielded by professional Rasch Winsteps software. The probabilistic modeling of the CIR module provides messages that are much more valuable to users and show the CIR advantage over classic test theory. Because of advances in computer technology, healthcare users who are familiar to MS Excel can easily apply the study CIR module to deal with continuous variables to benefit comparisons of data with a logistic distribution and model fit statistics.

Integrated Advanced Microwave Sounding Unit-A (AMSU-A) METOP Stress Analysis Report (Qual Level Random Vibration) A1 Module

NASA Technical Reports Server (NTRS)

Mehitretter, R.

1996-01-01

Stress analysis of the primary structure of the Meteorological Satellites Project (METSAT) Advanced Microwave Sounding Units-A, A1 Module performed using the Meteorological Operational (METOP) Qualification Level 9.66 grms Random Vibration PSD Spectrum is presented. The random vibration structural margins of safety and natural frequency predictions are summarized.

Advanced information processing system: Input/output system services

NASA Technical Reports Server (NTRS)

Masotto, Tom; Alger, Linda

1989-01-01

The functional requirements and detailed specifications for the Input/Output (I/O) Systems Services of the Advanced Information Processing System (AIPS) are discussed. The introductory section is provided to outline the overall architecture and functional requirements of the AIPS system. Section 1.1 gives a brief overview of the AIPS architecture as well as a detailed description of the AIPS fault tolerant network architecture, while section 1.2 provides an introduction to the AIPS systems software. Sections 2 and 3 describe the functional requirements and design and detailed specifications of the I/O User Interface and Communications Management modules of the I/O System Services, respectively. Section 4 illustrates the use of the I/O System Services, while Section 5 concludes with a summary of results and suggestions for future work in this area.

Development of a VOR/DME model for an advanced concepts simulator

NASA Technical Reports Server (NTRS)

Steinmetz, G. G.; Bowles, R. L.

1984-01-01

The report presents a definition of a VOR/DME, airborne and ground systems simulation model. This description was drafted in response to a need in the creation of an advanced concepts simulation in which flight station design for the 1980 era can be postulated and examined. The simulation model described herein provides a reasonable representation of VOR/DME station in the continental United States including area coverage by type and noise errors. The detail in which the model has been cast provides the interested researcher with a moderate fidelity level simulator tool for conducting research and evaluation of navigator algorithms. Assumptions made within the development are listed and place certain responsibilities (data bases, communication with other simulation modules, uniform round earth, etc.) upon the researcher.

Advanced photoelectric effect experiment beamline at Elettra: A surface science laboratory coupled with Synchrotron Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Panaccione, G.; Vobornik, I.; Fujii, J.

2009-04-15

We report the main characteristics of the advanced photoelectric effect experiments beamline, operational at Elettra storage ring, featuring a fully independent double branch scheme obtained by the use of chicane undulators and able to keep polarization control in both linear and circular mode. The paper describes the novel technical solutions adopted, namely, (a) the design of a quasiperiodic undulator resulting in optimized suppression of higher harmonics over a large photon energy range (10-100 eV), (b) the thermal stability of optics under high heat load via cryocoolers, and (c) the end station interconnected setup allowing full access to off-beam and on-beammore » facilities and, at the same time, the integration of users' specialized sample growth chambers or modules.« less

Recent advancements in electrospinning design for tissue engineering applications: A review.

PubMed

Kishan, Alysha P; Cosgriff-Hernandez, Elizabeth M

2017-10-01

Electrospinning, a technique used to fabricate fibrous scaffolds, has gained popularity in recent years as a method to produce tissue engineered grafts with architectural similarities to the extracellular matrix. Beyond its versatility in material selection, electrospinning also provides many tools to tune the fiber morphology and scaffold geometry. Recent efforts have focused on extending the capabilities of electrospinning to produce scaffolds that better recapitulate tissue properties and enhance regeneration. This review highlights these advancements by providing an overview of the processing variables and setups used to modulate scaffold architecture, discussing strategies to improve cellular infiltration and guide cell behavior, and providing a summary of electrospinning applications in tissue engineering. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 2892-2905, 2017. © 2017 Wiley Periodicals, Inc.

Advances in protease engineering for laundry detergents.

PubMed

Vojcic, Ljubica; Pitzler, Christian; Körfer, Georgette; Jakob, Felix; Ronny Martinez; Maurer, Karl-Heinz; Schwaneberg, Ulrich

2015-12-25

Proteases are essential ingredients in modern laundry detergents. Over the past 30 years, subtilisin proteases employed in the laundry detergent industry have been engineered by directed evolution and rational design to tailor their properties towards industrial demands. This comprehensive review discusses recent success stories in subtilisin protease engineering. Advances in protease engineering for laundry detergents comprise simultaneous improvement of thermal resistance and activity at low temperatures, a rational strategy to modulate pH profiles, and a general hypothesis for how to increase promiscuous activity towards the production of peroxycarboxylic acids as mild bleaching agents. The three protease engineering campaigns presented provide in-depth analysis of protease properties and have identified principles that can be applied to improve or generate enzyme variants for industrial applications beyond laundry detergents. Copyright © 2015 Elsevier B.V. All rights reserved.

Solid rocket technology advancements for space tug and IUS applications

NASA Technical Reports Server (NTRS)

Ascher, W.; Bailey, R. L.; Behm, J. W.; Gin, W.

1975-01-01

In order for the shuttle tug or interim upper stage (IUS) to capture all the missions in the current mission model for the tug and the IUS, an auxiliary or kick stage, using a solid propellant rocket motor, is required. Two solid propellant rocket motor technology concepts are described. One concept, called the 'advanced propulsion module' motor, is an 1800-kg, high-mass-fraction motor, which is single-burn and contains Class 2 propellent. The other concept, called the high energy upper stage restartable solid, is a two-burn (stop-restartable on command) motor which at present contains 1400 kg of Class 7 propellant. The details and status of the motor design and component and motor test results to date are presented, along with the schedule for future work.

Planar millimeter wave radar frontend for automotive applications

NASA Astrophysics Data System (ADS)

Grubert, J.; Heyen, J.; Metz, C.; Stange, L. C.; Jacob, A. F.

2003-05-01

A fully integrated planar sensor for 77 GHz automotive applications is presented. The frontend consists of a transceiver multichip module and an electronically steerable microstrip patch array. The antenna feed network is based on a modified Rotman-lens and connected to the array in a multilayer approach offering higher integration. Furthermore, the frontend comprises a phase lock loop to allow proper frequency-modulated continuous wave (FMCW) radar operation. The latest experimental results verify the functionality of this advanced frontend design featuring automatic cruise control, precrash sensing and cut-in detection. These promising radar measurements give reason to a detailed theoretical investigation of system performance. Employing commercially available MMIC various circuit topologies are compared based on signal-tonoise considerations. Different scenarios for both sequential and parallel lobing hint to more advanced sensor designs and better performance. These improvements strongly depend on the availability of suitable MMIC and reliable packaging technologies. Within our present approach possible future MMIC developments are already considered and, thus, can be easily adapted by the flexible frontend design. Es wird ein integrierter planarer Sensor für 77 GHz Radaranwendungen vorgestellt. Das Frontend besteht aus einem Sende- und Empfangs-Multi-Chip-Modul und einer elektronisch schwenkbaren Antenne. Das Speisenetzwerk der Antenne basiert auf einer modifizierten Rotman- Linse. Für eine kompakte Bauweise sind Antenne und Speisenetzwerk mehrlagig integriert. Weiterhin umfasst das Frontend eine Phasenregelschleife für eine präzise Steuerung des frequenzmodulierten Dauerstrichradars. Die aktuellen Messergebnisse bestätigen die Funktionalit¨at dieses neuartigen Frontend-Designs, das automatische Geschwindigkeitsregelung, Kollisionswarnung sowie Nahbereichsüberwachung ermöglicht. Die Qualität der Messergebnisse hat weiterführende theoretische Untersuchungen über die potenzielle Systemleistungsfähigkeit motiviert. Unter Berücksichtigung von kommerziell erhältlichenMMICs werden verschiedene Schaltungstopologien auf der Grundlage des Signal-Rausch-Verhältnisses verglichen. Sowohl für sequenzielle als auch für parallele Ansteuerung der Antennenkeulen wird eine deutliche Leistungssteigerung ermittelt. Diese Verbesserungen hängen maßgeblich von der Verfügbarkeit geeigneter MMICs und einer zuverlässigen Aufbau- und Verbindungstechnik ab. Das vorliegende Frontend-Konzept kann auf Grund seiner Flexibilität leicht an derlei zukünftige Entwicklungen angepasst werden.

Advanced telemetry systems for payloads. Technology needs, objectives and issues

NASA Technical Reports Server (NTRS)

1990-01-01

The current trends in advanced payload telemetry are the new developments in advanced modulation/coding, the applications of intelligent techniques, data distribution processing, and advanced signal processing methodologies. Concerted efforts will be required to design ultra-reliable man-rated software to cope with these applications. The intelligence embedded and distributed throughout various segments of the telemetry system will need to be overridden by an operator in case of life-threatening situations, making it a real-time integration issue. Suitable MIL standards on physical interfaces and protocols will be adopted to suit the payload telemetry system. New technologies and techniques will be developed for fast retrieval of mass data. Currently, these technology issues are being addressed to provide more efficient, reliable, and reconfigurable systems. There is a need, however, to change the operation culture. The current role of NASA as a leader in developing all the new innovative hardware should be altered to save both time and money. We should use all the available hardware/software developed by the industry and use the existing standards rather than inventing our own.

An Ultrafast Switchable Terahertz Polarization Modulator Based on III-V Semiconductor Nanowires.

PubMed

Baig, Sarwat A; Boland, Jessica L; Damry, Djamshid A; Tan, H Hoe; Jagadish, Chennupati; Joyce, Hannah J; Johnston, Michael B

2017-04-12

Progress in the terahertz (THz) region of the electromagnetic spectrum is undergoing major advances, with advanced THz sources and detectors being developed at a rapid pace. Yet, ultrafast THz communication is still to be realized, owing to the lack of practical and effective THz modulators. Here, we present a novel ultrafast active THz polarization modulator based on GaAs semiconductor nanowires arranged in a wire-grid configuration. We utilize an optical pump-terahertz probe spectroscopy system and vary the polarization of the optical pump beam to demonstrate ultrafast THz modulation with a switching time of less than 5 ps and a modulation depth of -8 dB. We achieve an extinction of over 13% and a dynamic range of -9 dB, comparable to microsecond-switchable graphene- and metamaterial-based THz modulators, and surpassing the performance of optically switchable carbon nanotube THz polarizers. We show a broad bandwidth for THz modulation between 0.1 and 4 THz. Thus, this work presents the first THz modulator which combines not only a large modulation depth but also a broad bandwidth and picosecond time resolution for THz intensity and phase modulation, making it an ideal candidate for ultrafast THz communication.

Evaluation of reliability modeling tools for advanced fault tolerant systems

NASA Technical Reports Server (NTRS)

Baker, Robert; Scheper, Charlotte

1986-01-01

The Computer Aided Reliability Estimation (CARE III) and Automated Reliability Interactice Estimation System (ARIES 82) reliability tools for application to advanced fault tolerance aerospace systems were evaluated. To determine reliability modeling requirements, the evaluation focused on the Draper Laboratories' Advanced Information Processing System (AIPS) architecture as an example architecture for fault tolerance aerospace systems. Advantages and limitations were identified for each reliability evaluation tool. The CARE III program was designed primarily for analyzing ultrareliable flight control systems. The ARIES 82 program's primary use was to support university research and teaching. Both CARE III and ARIES 82 were not suited for determining the reliability of complex nodal networks of the type used to interconnect processing sites in the AIPS architecture. It was concluded that ARIES was not suitable for modeling advanced fault tolerant systems. It was further concluded that subject to some limitations (the difficulty in modeling systems with unpowered spare modules, systems where equipment maintenance must be considered, systems where failure depends on the sequence in which faults occurred, and systems where multiple faults greater than a double near coincident faults must be considered), CARE III is best suited for evaluating the reliability of advanced tolerant systems for air transport.

Automation in the Space Station module power management and distribution Breadboard

NASA Technical Reports Server (NTRS)

Walls, Bryan; Lollar, Louis F.

1990-01-01

The Space Station Module Power Management and Distribution (SSM/PMAD) Breadboard, located at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama, models the power distribution within a Space Station Freedom Habitation or Laboratory module. Originally designed for 20 kHz ac power, the system is now being converted to high voltage dc power with power levels on a par with those expected for a space station module. In addition to the power distribution hardware, the system includes computer control through a hierarchy of processes. The lowest level process consists of fast, simple (from a computing standpoint) switchgear, capable of quickly safing the system. The next level consists of local load center processors called Lowest Level Processors (LLP's). These LLP's execute load scheduling, perform redundant switching, and shed loads which use more than scheduled power. The level above the LLP's contains a Communication and Algorithmic Controller (CAC) which coordinates communications with the highest level. Finally, at this highest level, three cooperating Artificial Intelligence (AI) systems manage load prioritization, load scheduling, load shedding, and fault recovery and management. The system provides an excellent venue for developing and examining advanced automation techniques. The current system and the plans for its future are examined.

Phased array-fed antenna configuration study

NASA Technical Reports Server (NTRS)

Crosswell, W. F.; Ball, D. E.; Taylor, R. C.

1983-01-01

The scope of this contract entails a configuration study for a phased array fed transmit antenna operating in the frequency band of 17.7 to 20.2 GHz. This initial contract provides a basis for understanding the design limitations and advantages of advanced phased array and cluster feeds (both utilizing intergral MMIC modules) illuminating folded reflector optics (both near field and focused types). Design parametric analyses are performed utilizing as constraints the objective secondary performance requirements of the Advanced Communications Technology Satellite (Table 1.0). The output of the study provides design information which serves as a data base for future active phased array fed antenna studies such as detailed designs required to support the development of a ground tested breadboard. In general, this study is significant because it provides the antenna community with an understanding of the basic principles which govern near field phased scanned feed effects on secondary reflector system performance. Although several articles have been written on analysis procedures and results for these systems, the authors of this report have observed phenomenon of near field antenna systems not previously documented. Because the physical justification for the exhibited performance is provided herein, the findings of this study add a new dimension to the available knowledge of the subject matter.

Space Transportation Engine Program (STEP), phase B

NASA Technical Reports Server (NTRS)

1990-01-01

The Space Transportation Engine Program (STEP) Phase 2 effort includes preliminary design and activities plan preparation that will allow smooth and time transition into a Prototype Phase and then into Phases 3, 4, and 5. A Concurrent Engineering approach using Total Quality Management (TQM) techniques, is being applied to define an oxygen-hydrogen engine. The baseline from Phase 1/1' studies was used as a point of departure for trade studies and analyses. Existing STME system models are being enhanced as more detailed module/component characteristics are determined. Preliminary designs for the open expander, closed expander, and gas generator cycles were prepared, and recommendations for cycle selection made at the Design Concept Review (DCR). As a result of July '90 DCR, and information subsequently supplied to the Technical Review Team, a gas generator cycle was selected. Results of the various Advanced Development Programs (ADP's) for the Advanced Launch Systems (ALS) were contributive to this effort. An active vehicle integration effort is supplying the NASA, Air Force, and vehicle contractors with engine parameters and data, and flowing down appropriate vehicle requirements. Engine design and analysis trade studies are being documented in a data base that was developed and is being used to organize information. To date, seventy four trade studies were input to the data base.

Design of a High-Speed and Compact Electro-Optic Modulator using Silicon-Germanium HBT

NASA Astrophysics Data System (ADS)

Neogi, Tuhin Guha

Optical interconnects between electronics systems have attracted significant attention and development for a number of years because optical links have demonstrated potential advantages for high-speed, low-power, and interference immunity. With increasing system speed and greater bandwidth requirements, the distance over which optical communication is useful has continually decreased to chip-to-chip and on-chip levels. Monolithic integration of photonics and electronics will significantly reduce the cost of optical components and further combine the functionalities of chips on the same or different boards or systems. Modulators are one of the fundamental building blocks for optical interconnects. High-speed modulation and low driving voltage are the keys for the device's practical use. In this study two separate designs show that using a graded base SiGe HBT we can modulate light at high speeds with moderate length and dynamic power consumption. The first design analyzes the terminal characteristics of the HBT and a close match is obtained in comparison with npn HBTs using IBM.s 8HP technology. This suggests that the modulator can be manufactured using the IBM 8HP fabrication process. At a sub-collector depth of 0.4 mum and at a base-emitter swing of 0 V to 1.1 V, this model predicts a bit rate of 80 Gbit/s. Optical simulations predict a pi phase shift length (Lpi) of 240.8 mum with an extinction ratio of 7.5 dB at a wavelength of 1.55 mum. Additionally, the trade-off between the switching speed, Lpi and propagation loss with a thinner sub-collector is analyzed and reported. The dynamic power consumption is reported to be 3.6 pJ /bit. The second design examine a theoretical aggressively-scaled SiGe HBT that may approximate a device that is two device generations more advanced than available today. At a base-emitter swing of 0 V to 1.0 V, this model predicts a bit rate of 250 Gbit/s. Optical simulations predict a pi phase shift length (Lpi) of 204 mum, with an extinction ratio of 13.2 dB at a wavelength of 1.55 mum. The dynamic power consumption is reported to be 2.01 pJ /bit. This study also discusses the design of driver circuitry at 80 Gbit/s with voltage swing levels of 1.03V. Finally the use of slow wave structures and use of SiGe HBT as a linear analog modulator is introduced.

Overview of the 1986 free-piston Stirling SP-100 activities at the NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1986-01-01

An overview of the NASA Lewis Research Center SP-100 free-piston Stirling engine activities is presented. These activities include a free-piston Stirling space-power technology feasibility demonstration project as part of the SP-100 program being conducted in support of the Department of Defennse (DOD), Department of Energy (DOE), and NASA. The space-power Stirling advanced technology effort, under SP-100, addresses the status of the 25 kWe Space Power Demonstrator Engine (SPDE) including test results. Future space-power projections are presented along with a description of a study that will investigate the feasibility of scaling a single-cylinder free-piston Stirling space-power module to the 150 kW power range. Design parameters and conceptual design features will be presented for a 25 kWe, single-cylinder free-piston Stirling space-power converter. A description of a hydrodynamic gas bearing concept is presented whereby the displacer of a 1 kWe free-piston Stirling engine is modified to demonstrate the bearing concept. And finally the goals of a conceptual design for a 25 kWe Solar Advanced Stirling Conversion System capable of delivering electric power to an electric utility grid are discussed.

Overview of the 1986 free-piston Stirling SP-100 activities at the NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1986-01-01

An overview of the NASA Lewis Research Center SP-100 free-piston Stirling engine activities is presented. These activities include a free-piston Stirling space-power technology feasibility demonstration project as part of the SP-100 program being conducted in support of the Department of Defense (DOD), Department of Energy (DOE), and NASA. The space-power Stirling advanced technology effort, under SP-100, addresses the status of the 25 kWe Space Power Demonstrator Engine (SPDE) including test results. Future space-power projections are presented along with a description of a study that will investigate the feasibility of scaling a single-cylinder free-piston Stirling space-power module to the 150 kW power range. Design parameters and conceptual design features will be presented for a 25 kWe, single-cylinder free-piston Stirling space-power converter. A description of a hydrodynamic gas bearing concept is presented whereby the displacer of a 1 kWe free-piston Stirling engine is modified to demonstrate the bearing concept. And finally the goals of a conceptual design for a 25 kWe Solar Advanced Stirling Conversion System capable of delivering electric power to an electric utility grid are discussed.

Modulating Oxidative Stress and Inflammation in Elders: The MOXIE Study

PubMed Central

Ellis, Amy Cameron; Dudenbostel, Tanja; Locher, Julie L.; Crowe-White, Kristi

2016-01-01

Cardiovascular disease (CVD) is the leading cause of death among women in the United States. Endothelial dysfunction and arterial stiffness increase with advancing age and are early predictors of future CVD outcomes. We designed the Modulating Oxidative Stress and Inflammation in Elders (MOXIE) study to examine the effects of 100% watermelon juice as a “food-first” intervention to reduce CVD risk among African American (AA) and European American (EA) women aged 55–69 years. Vascular dysfunction is more pronounced in AA compared to EA women due in part to lower nitric oxide bioavailability caused by higher oxidative stress. However, bioactive compounds in watermelon may improve vascular function by increasing nitric oxide bioavailability and antioxidant capacity. This trial will use a randomized, placebo-controlled, crossover design to investigate the potential of 100% watermelon juice to positively impact various robust measures of vascular function as well as serum biomarkers of oxidative stress and antioxidant capacity. This nutrition intervention and its unique methodology to examine both clinical and mechanistic outcomes are described in this article. PMID:27897608

Passive Two-Phase Cooling for Automotive Power Electronics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moreno, G.; Jeffers, J. R.; Narumanchi, S.

2014-01-01

Experiments were conducted to evaluate the use of a passive two-phase cooling strategy as a means of cooling automotive power electronics. The proposed cooling approach utilizes an indirect cooling configuration to alleviate some reliability concerns and to allow the use of conventional power modules. An inverter-scale proof-of-concept cooling system was fabricated and tested using the refrigerants hydrofluoroolefin HFO-1234yf and hydrofluorocarbon HFC-245 fa. Results demonstrated that the system can dissipate at least 3.5 kW of heat with 250 cm3 of HFC-245fa. An advanced evaporator concept that incorporates features to improve performance and reduce its size was designed. Simulation results indicate themore » concept's thermal resistance can be 58% to 65% lower than automotive dual-side-cooled power modules. Tests were also conducted to measure the thermal performance of two air-cooled condensers-plain and rifled finned tube designs. The results combined with some analysis were then used to estimate the required condenser size per operating conditions and maximum allowable system (i.e., vapor and liquid) temperatures.« less

Passive Two-Phase Cooling of Automotive Power Electronics: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moreno, G.; Jeffers, J. R.; Narumanchi, S.

2014-08-01

Experiments were conducted to evaluate the use of a passive two-phase cooling strategy as a means of cooling automotive power electronics. The proposed cooling approach utilizes an indirect cooling configuration to alleviate some reliability concerns and to allow the use of conventional power modules. An inverter-scale proof-of-concept cooling system was fabricated, and tests were conducted using the refrigerants hydrofluoroolefin HFO-1234yf and hydrofluorocarbon HFC-245fa. Results demonstrated that the system can dissipate at least 3.5 kW of heat with 250 cm3 of HFC-245fa. An advanced evaporator design that incorporates features to improve performance and reduce size was conceived. Simulation results indicate itsmore » thermal resistance can be 37% to 48% lower than automotive dual side cooled power modules. Tests were also conducted to measure the thermal performance of two air-cooled condensers--plain and rifled finned tube designs. The results combined with some analysis were then used to estimate the required condenser size per operating conditions and maximum allowable system (i.e., vapor and liquid) temperatures.« less

The "Frankenplasmid" lab: an investigative exercise for teaching recombinant DNA methods.

PubMed

Dean, Derek M; Wilder, Jason A

2011-01-01

We describe an investigative laboratory module designed to give college undergraduates strong practical and theoretical experience with recombinant DNA methods within 3 weeks. After deducing restriction enzyme maps for two different plasmids, students ligate the plasmids together in the same reaction, transform E. coli with this mixture of ligated DNA, and plate the cells on media that specifically select for hybrid plasmids. The main goal of the assignment is for students to deduce the gene map of one hybrid "Frankenplasmid" using the LacZ phenotype of its transformants, PCR, and restriction mapping. Our protocol results in a number of possible outcomes, meaning that students are mapping truly unknown plasmids. The open-ended nature of this assignment results in an effective module that teaches recombinant DNA procedures while engaging students with its investigative approach, increasing complexity, and puzzle-like quality. Moreover, the modular design of the activity allows it to be adapted to a more limited schedule, introductory courses, or more advanced courses. Copyright © 2011 International Union of Biochemistry and Molecular Biology, Inc.

Advanced GF(3²) nonbinary LDPC coded modulation with non-uniform 9-QAM outperforming star 8-QAM.

PubMed

Liu, Tao; Lin, Changyu; Djordjevic, Ivan B

2016-06-27

In this paper, we first describe a 9-symbol non-uniform signaling scheme based on Huffman code, in which different symbols are transmitted with different probabilities. By using the Huffman procedure, prefix code is designed to approach the optimal performance. Then, we introduce an algorithm to determine the optimal signal constellation sets for our proposed non-uniform scheme with the criterion of maximizing constellation figure of merit (CFM). The proposed nonuniform polarization multiplexed signaling 9-QAM scheme has the same spectral efficiency as the conventional 8-QAM. Additionally, we propose a specially designed GF(3²) nonbinary quasi-cyclic LDPC code for the coded modulation system based on the 9-QAM non-uniform scheme. Further, we study the efficiency of our proposed non-uniform 9-QAM, combined with nonbinary LDPC coding, and demonstrate by Monte Carlo simulation that the proposed GF(2³) nonbinary LDPC coded 9-QAM scheme outperforms nonbinary LDPC coded uniform 8-QAM by at least 0.8dB.

Miniature Optical Communications Transceiver (MOCT)

NASA Technical Reports Server (NTRS)

Conklin, John W.; Hunter, Roger C.; Baker, Christopher

2017-01-01

This project will advance the technology readiness of the Miniature Optical Communications Transceiver (MOCT) from TRL 3 to TRL 4. MOCT consists of a novel software-defined pulse modulator (SDPM),integrated laser system, and avalanche photodetection system, and is designed for optical communications between small spacecraft, including CubeSats, using a pulse position modulation (PPM) scheme. PPM encodes data in the timing of optical pulses with respect to a set of timing windows known as slots. The MOCT design focuses on power-efficiency making it particularly interesting for small satellites. We have demonstrated in the laboratory that this technology can generate shorter than 1 nanosecond-wide 1550 nanometer (nm) optical pulses with better than 50 picosecond (ps) timing accuracy. The timing resolution of this system is roughly a factor of four better than previously flown systems, meaning that it can transmit more bits of data with each optical pulse. Because this technology can both generate and time stamp the arrival of short optical pulses with 50 ps precision, it simultaneously provides power efficient communications and relative ranging between small spacecraft at the centimeter (cm) level.

Periodically microstructured composite films made by electric- and magnetic-directed colloidal assembly

PubMed Central

Demirörs, Ahmet Faik; Courty, Diana; Libanori, Rafael; Studart, André R.

2016-01-01

Living organisms often combine soft and hard anisotropic building blocks to fabricate composite materials with complex microstructures and outstanding mechanical properties. An optimum design and assembly of the anisotropic components reinforces the material in specific directions and sites to best accommodate multidirectional external loads. Here, we fabricate composite films with periodic modulation of the soft–hard microstructure by simultaneously using electric and magnetic fields. We exploit forefront directed-assembly approaches to realize highly demanded material microstructural designs and showcase a unique example of how one can bridge colloidal sciences and composite technology to fabricate next-generation advanced structural materials. In the proof-of-concept experiments, electric fields are used to dictate the position of the anisotropic particles through dielectrophoresis, whereas a rotating magnetic field is used to control the orientation of the particles. By using such unprecedented control over the colloidal assembly process, we managed to fabricate ordered composite microstructures with up to 2.3-fold enhancement in wear resistance and unusual site-specific hardness that can be locally modulated by a factor of up to 2.5. PMID:27071113

Design and test status for life support applications of SPE oxygen generation systems. [Solid Polymer Electrolyte

NASA Technical Reports Server (NTRS)

Titterington, W. A.; Erickson, A. C.

1975-01-01

An advanced six-man rated oxygen generation system has been fabricated and tested as part of a NASA/JSC technology development program for a long lived, manned spacecraft life support system. Details of the design and tests results are presented. The system is based on the Solid Polymer Electrolyte (SPE) water electrolysis technology and its nominal operating conditions are 2760 kN/sq m (400 psia) and 355 K (180 F) with an electrolysis module current density capability up to 350 mA/sq cm (326 ASF). The system is centered on a 13-cell SPE water electrolysis module having a single cell active area of 214 sq cm (33 sq in) and it incorporates instrumentation and controls for single pushbutton automatic startup/shutdown, component fault detection and isolation, and self-contained sensors and controls for automatic safe emergency shutdown. The system has been tested in both the orbital cyclic and continuous mode of operation. Various parametric tests have been completed to define the system capability for potential application in spacecraft environmental systems.

Long-distance delivery of multi-channel polarization signals in nuclear fusion research

NASA Astrophysics Data System (ADS)

Ko, Jinseok; Chung, Jinil; Lee, Kyuhang

2017-04-01

A polarization-preserving optical system that includes a dual photoelastic modulator (PEM) has been designed and fabricated for the motional Stark effect (MSE) diagnostic system which measures internal magnetic field structures inside the tokamak for the Korea Superconducting Tokamak Advanced Research. The collection optics located outside the vacuum window is composed of four lenses, a dielectric coated mirror, and a dichroic beam splitter in addition to the PEM and a polarizer. The fiber dissector is designed based on the focal plane that aligns 25 lines of sight, each of which constitutes a bundle of 19 600-μm fibers. The fibers run about 40 m from the front optics in the tokamak vacuum vessel to the detector in the diagnostic area remote from the tokamak hall. This takes the advantage of the fact that the polarization information is intensity-modulated once going through the PEM and the polarizer. The polarization signals measured by the MSE diagnostic successfully demonstrates its proof-of-principle physics that is critical in the stable and steady-state operation of the tokamak plasmas.

Advanced Chemical Precipitation Softening. Training Module 2.217.4.77.

ERIC Educational Resources Information Center

McMullen, L. D.

This document is an instructional module package prepared in objective form for use by an instructor familiar with the operation and maintenance of a chemical precipitation softening system. Included are objectives, instructor guides, student handouts and transparency masters. This is the third level of a three module series. This module considers…

A Usability Study of Interactive Web-Based Modules

ERIC Educational Resources Information Center

Girard, Tulay; Pinar, Musa

2011-01-01

This research advances the understanding of the usability of marketing case study modules in the area of interactive web-based technologies through the assignment of seven interactive case modules in a Principles of Marketing course. The case modules were provided for marketing students by the publisher, McGraw Hill Irwin, of the…

Design and control of multifunctional sorting and training platform based on PLC control

NASA Astrophysics Data System (ADS)

Wan, Hongqiang; Ge, Shuai; Han, Peiying; Li, Fancong; Zhang, Simiao

2018-05-01

Electromechanical integration, as a multi-disciplinary subject, has been paid much attention by universities and is widely used in the automation production of enterprises. Aiming at the problem of the lack of control among enterprises and the lack of training among colleges and universities, this paper presents a design of multifunctional sorting training platform based on PLC control. Firstly, the structure of the platform is determined and three-dimensional modeling is done. Then design the platform's aerodynamic control and electrical control. Finally, realize the platform sorting function through PLC programming and configuration software development. The training platform can be used to design the practical training experiment, which has a strong advance and pertinence in the electromechanical integration teaching. At the same time, the platform makes full use of modular thinking to make the sorting modules more flexible. Compared with the traditional training platform, its teaching effect is more significant.

Antennas for 20/30 GHz and beyond

NASA Technical Reports Server (NTRS)

Chen, C. Harry; Wong, William C.; Hamada, S. Jim

1989-01-01

Antennas of 20/30 GHz and higher frequency, due to the small wavelength, offer capabilities for many space applications. With the government-sponsored space programs (such as ACTS) in recent years, the industry has gone through the learning curve of designing and developing high-performance, multi-function antennas in this frequency range. Design and analysis tools (such as the computer modelling used in feedhorn design and reflector surface and thermal distortion analysis) are available. The components/devices (such as BFN's, weight modules, feedhorns and etc.) are space-qualified. The manufacturing procedures (such as reflector surface control) are refined to meet the stringent tolerance accompanying high frequencies. The integration and testing facilities (such as Near-Field range) also advance to facilitate precision assembling and performance verification. These capabilities, essential to the successful design and development of high-frequency spaceborne antennas, shall find more space applications (such as ESGP) than just communications.

Electron-Electron Interactions in Artificial Graphene

NASA Astrophysics Data System (ADS)

Räsänen, E.; Rozzi, C. A.; Pittalis, S.; Vignale, G.

2012-06-01

Recent advances in the creation and modulation of graphenelike systems are introducing a science of “designer Dirac materials”. In its original definition, artificial graphene is a man-made nanostructure that consists of identical potential wells (quantum dots) arranged in an adjustable honeycomb lattice in the two-dimensional electron gas. As our ability to control the quality of artificial graphene samples improves, so grows the need for an accurate theory of its electronic properties, including the effects of electron-electron interactions. Here we determine those effects on the band structure and on the emergence of Dirac points.

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lian, Jiazhang; HamediRad, Mohammad; Zhao, Huimin

Thanks to its ease of use, modularity, and scalability, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been increasingly used in the design and engineering of Saccharomyces cerevisiae, one of the most popular hosts for industrial biotechnology. This review summarizes the recent development of this disruptive technology for metabolic engineering applications, including CRISPR-mediated gene knock-out and knock-in as well as transcriptional activation and interference. More importantly, multi-functional CRISPR systems that combine both gain- and loss-of-function modulations for combinatorial metabolic engineering are highlighted.

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

DOE PAGES

Lian, Jiazhang; HamediRad, Mohammad; Zhao, Huimin

2018-04-18

Thanks to its ease of use, modularity, and scalability, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been increasingly used in the design and engineering of Saccharomyces cerevisiae, one of the most popular hosts for industrial biotechnology. This review summarizes the recent development of this disruptive technology for metabolic engineering applications, including CRISPR-mediated gene knock-out and knock-in as well as transcriptional activation and interference. More importantly, multi-functional CRISPR systems that combine both gain- and loss-of-function modulations for combinatorial metabolic engineering are highlighted.

Fusion Advanced Design Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

El-Guebaly, Laila; Henderson, Douglass; Wilson, Paul

2017-03-24

During the January 1, 2013 – December 31, 2015 contract period, the UW Fusion Technology Institute personnel have actively participated in the ARIES-ACT and FESS-FNSF projects, led the nuclear and thermostructural tasks, attended several project meetings, and participated in all conference calls. The main areas of effort and technical achievements include updating and documenting the nuclear analysis for ARIES-ACT1, performing nuclear analysis for ARIES-ACT2, performing thermostructural analysis for ARIES divertor, performing disruption analysis for ARIES vacuum vessel, and developing blanket testing strategy and Materials Test Module for FNSF.

Engaging students in geodesy: A quantitative InSAR module for undergraduate tectonics and geophysics classes

NASA Astrophysics Data System (ADS)

Taylor, H.; Charlevoix, D. J.; Pritchard, M. E.; Lohman, R. B.

2013-12-01

In the last several decades, advances in geodetic technology have allowed us to significantly expand our knowledge of processes acting on and beneath the Earth's surface. Many of these advances have come as a result of EarthScope, a community of scientists conducting multidisciplinary Earth science research utilizing freely accessible data from a variety of instruments. The geodetic component of EarthScope includes the acquisition of synthetic aperture radar (SAR) images, which are archived at the UNAVCO facility. Interferometric SAR complements the spatial and temporal coverage of GPS and allows monitoring of ground deformation in remote areas worldwide. However, because of the complex software required for processing, InSAR data are not readily accessible to most students. Even with these challenges, exposure at the undergraduate level is important for showing how geodesy can be applied in various areas of the geosciences and for promoting geodesy as a future career path. Here we present a module focused on exploring the tectonics of the western United States using InSAR data for use in undergraduate tectonics and geophysics classes. The module has two major objectives: address topics concerning tectonics in the western U.S. including Basin and Range extension, Yellowstone hotspot activity, and creep in southern California, and familiarize students with how imperfect real-world data can be manipulated and interpreted. Module questions promote critical thinking skills and data literacy by prompting students to use the information given to confront and question assumptions (e.g. 'Is there a consistency between seismic rates and permanent earthquake deformation? What other factors might need to be considered besides seismicity?'). The module consists of an introduction to the basics of InSAR and three student exercises, each focused on one of the topics listed above. Students analyze pre-processed InSAR data using MATLAB, or an Excel equivalent, and draw on GPS and creepmeter datasets for comparison. Exercises were developed following Backward Design and initial feedback was provided by curriculum experts and several undergraduate students. Evaluation of the impact of the module on student understanding of InSAR will be conducted in the fall with volunteers from tectonics and geophysics classes. Students will be given pre- and post-module surveys to evaluate overall effectiveness and areas for improvement. This module will be disseminated on the UNAVCO website after finalization.

Operational Evaluation of the Root Modules of the Advanced Plant Habitat

NASA Technical Reports Server (NTRS)

Monje, O.

2014-01-01

Photosynthetic and growth data were collected on APH Root Module. Described Stand pipe system for active moisture control. Tested germination in wicks. Evaluated EC-5 moisture sensors. Demonstrated that Wheat plants can grow in the APH Root Module.

Advanced photovoltaic power systems using tandem GaAs/GaSb concentrator modules

NASA Technical Reports Server (NTRS)

Fraas, L. M.; Kuryla, M. S.; Pietila, D. A.; Sundaram, V. S.; Gruenbaum, P. E.; Avery, J. E.; Dihn, V.; Ballantyne, R.; Samuel, C.

1992-01-01

In 1989, Boeing announced the fabrication of a tandem gallium concentrator solar cell with an energy conversion efficiency of 30 percent. This research breakthrough has now led to panels which are significantly smaller, lighter, more radiation resistant, and potentially less expensive than the traditional silicon flat plate electric power supply. The new Boeing tandem concentrator (BTC) module uses an array of lightweight silicone Fresnel lenses mounted on the front side of a light weight aluminum honeycomb structure to focus sunlight onto small area solar cells mounted on a thin back plane. This module design is shown schematically. The tandem solar cell in this new module consists of a gallium arsenide light sensitive cell with a 24 percent energy conversion efficiency stacked on top of a gallium antimonide infrared sensitive cell with a conversion efficiency of 6 percent. This gives a total efficiency 30 percent for the cell-stack. The lens optical efficiency is typically 85 percent. Discounting for efficiency losses associated with lens packing, cell wiring, and cell operating temperature still allows for a module efficiency of 22 percent which leads to a module power density of 300 Watts/sq. m. This performance provides more than twice the power density available from a single crystal silicon flat plate module and at least four times the power density available from amorphous silicon modules. The fact that the lenses are only 0.010 ft. thick and the aluminum foil back plane is only 0.003 ft. thick leads to a very lightweight module. Although the cells are an easy to handle thickness of 0.020 ft., the fact that they are small, occupying one-twenty-fifth of the module area, means that they add little to the module weight. After summing all the module weights and given the high module power, we find that we are able to fabricate BTC modules with specific power of 100 watts/kg.

Design, fabrication, test qualification and price analysis of a third generation solar cell module

NASA Technical Reports Server (NTRS)

1982-01-01

The design, fabrication, test, and qualification of a third generation intermediate load solar cell module are presented. A technical discussion of the detailed module design, preliminary design review, design modifications, and environmental testing are included. A standardized pricing system is utilized to establish the cost competitiveness of this module design.

Concept and design of a fiber-optic and an I2C hybrid sensor bus system for telecommunication satellites

NASA Astrophysics Data System (ADS)

Putzer, P.; Hurni, A.; Manhart, M.; Tiefenbeck, C.; Plattner, M.; Koch, A. W.

2012-04-01

In this paper the concept and design of the Hybrid Sensor Bus (HSB) system for telecommunication satellites is presented. The HSB development in the frame of an ESA-ARTES project has been started in 2011 and the system will be tested as flight demonstrator onboard the German Heinrich Hertz communication satellite (H2Sat) in 2016. In state-of-the-art telecommunication platforms hundreds of sensors are necessary for satellite control and monitoring. The sensors are wired point-to-point (p2p) to the satellite management unit (SMU) which results in a high mass impact but preliminary increases AIT effort and thereby the overall satellite costs. Sensor bus architectures reduce AIT cost by reduction of wiring effort, reduction in required test time and by providing a flexible sensor network topology. The HSB system is based on a modular concept including a controller module, a fiber-optic interrogator module and an I²C electric interrogator module The HSB system provides advanced performance which includes programmable and sensor specific alarm functions, averaging of dedicated sensor values and thereby a reduction of SMU processor load. The combination of electrical I2C sensors for punctual resolved measurements and fiber-optic sensors for e.g. thermal mapping of panels by embedding sensor fibers in the satellite structures results in a versatile system. In this paper we present the design of the HSB system taking into account the requirements from European platform manufacturers. The HSB design yields a product which can be implemented as replacement of standard p2p systems to build up a more cost efficient sensor system for geostationary satellites.

Soil Water: Advanced Crop and Soil Science. A Course of Study.

ERIC Educational Resources Information Center

Miller, Larry E.

The course of study represents the fourth of six modules in advanced crop and soil science and introduces the agriculture student to the topic of soil water. Upon completing the three day module, the student will be able to classify water as to its presence in the soil, outline the hydrological cycle, list the ways water is lost from the soil,…

Frequency Hopping, Multiple Frequency-Shift Keying, Coding, and Optimal Partial-Band Jamming.

DTIC Science & Technology

1982-08-01

receivers appropriate for these two strategies. Each receiver is noncoherent (a coherent receiver is generally impractical) and implements hard...Advances in Coding and Modulation for Noncoherent Channels Affected by Fading, Partial Band, and Multiple- . Access Interference, in A. J. Viterbi...Modulation for Noncoherent Channels Affected by Fading, Partial Band, and Multiple-Access interference, in A. J. Viterbi, ed., Advances in Coumunication

Computer-aided design of biological circuits using TinkerCell.

PubMed

Chandran, Deepak; Bergmann, Frank T; Sauro, Herbert M

2010-01-01

Synthetic biology is an engineering discipline that builds on modeling practices from systems biology and wet-lab techniques from genetic engineering. As synthetic biology advances, efficient procedures will be developed that will allow a synthetic biologist to design, analyze, and build biological networks. In this idealized pipeline, computer-aided design (CAD) is a necessary component. The role of a CAD application would be to allow efficient transition from a general design to a final product. TinkerCell is a design tool for serving this purpose in synthetic biology. In TinkerCell, users build biological networks using biological parts and modules. The network can be analyzed using one of several functions provided by TinkerCell or custom programs from third-party sources. Since best practices for modeling and constructing synthetic biology networks have not yet been established, TinkerCell is designed as a flexible and extensible application that can adjust itself to changes in the field. © 2010 Landes Bioscience

Upgrading the SPP-500-1 moisture separators-steam reheaters used in the Leningrad NPP turbine units

NASA Astrophysics Data System (ADS)

Legkostupova, V. V.; Sudakov, A. V.

2015-03-01

The specific features of existing designs of moisture separators-steam reheaters (MSRs) and experience gained with using them at nuclear power plants are considered. Main factors causing damage to and failures of MSRs are described: nonuniform distribution of wet steam flow among the separation modules, breakthrough of moisture through the separator (and sometimes also through the steam reheater), which may lead to the occurrence of additional thermal stresses and, hence, to thermal-fatigue damage to or stress corrosion cracking of metal. MSR failure results in a less efficient operation of the turbine unit as a whole and have an adverse effect on the reliability of the low-pressure cylinder's last-stage blades. By the time the design service life of the SPP-500-1 MSRs had been exhausted in power units equipped with RBMK-1000 reactors, the number of damages inflicted to both the separation part and to the pipework and heating surface tubes was so large, that a considerable drop of MSR effectiveness and turbine unit efficiency as a whole occurred. The design of the upgraded separation part used in the SPP-500-1 MSR at the Leningrad NPP is described and its effectiveness is shown, which was confirmed by tests. First, efforts taken to achieve more uniform distribution of moisture content over the perimeter and height of steam space downstream of the separation modules and to bring it to values close to the design ones were met with success. Second, no noticeable effect of the individual specific features of separation modules on the moisture content was revealed. Recommendations on elaborating advanced designs of moisture separators-steam reheaters are given: an MSR arrangement in which the separator is placed under or on the side from the steam reheater; axial admission of wet steam for ensuring its uniform distribution among the separation modules; inlet chambers with an extended preliminary separation system and devices for uniformly distributing steam flows in the separator; separated layout of the of the separator and steam reheater; and use of transversely finned tube bundles for organizing cross flow of steam over the tubes.

Automatic Layout Design for Power Module

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ning, Puqi; Wang, Fei; Ngo, Khai

The layout of power modules is one of the key points in power module design, especially for high power densities, where couplings are increased. In this paper, along with the design example, an automatic design processes by using a genetic algorithm are presented. Some practical considerations and implementations are introduced in the optimization of module layout design.

Transportation life cycle assessment (LCA) synthesis : life cycle assessment learning module series.

DOT National Transportation Integrated Search

2015-03-12

The Life Cycle Assessment Learning Module Series is a set of narrated, self-advancing slideshows on : various topics related to environmental life cycle assessment (LCA). This research project produced the first 27 of such modules, which : are freely...

The "medication interest model": an integrative clinical interviewing approach for improving medication adherence-part 2: implications for teaching and research.

PubMed

Shea, Shawn Christopher

2009-01-01

Over the past several decades, exciting advances have been made in the art and science of teaching clinical interviewing, which are supported by an ever-growing evidence base documenting their effectiveness. In this second article in a 2-part series, the training and research implications of an innovative approach to improving medication adherence based on these educational advances--the medication interest model (MIM)--are described. The objective is to provide an "insider's view" of how to creatively teach the MIM to case managers, as well as design state-of-the-art courses and research platforms dedicated to improving medication adherence through improved clinical interviewing skills in both nursing and medical student education. The teaching and research design concepts are applicable to all primary care settings as well as specialty areas from endocrinology and cardiology to psychiatry. Evidence-based advances in the teaching of clinical interviewing skills such as response-mode research, facilic supervision, microtraining, and macrotraining lend a distinctive quality and integrative power to the MIM. The model delineates several new platforms for training and research regarding the enhancement of medication adherence including an approach for collecting individual interviewing techniques into manageable "learning modules" amenable to competency evaluation and potential certification.

Treating autoimmune disorders with venom-derived peptides.

PubMed

Shen, Bingzheng; Cao, Zhijian; Li, Wenxin; Sabatier, Jean-Marc; Wu, Yingliang

2017-09-01

The effective treatment of autoimmune diseases remains a challenge. Voltage-gated potassium Kv1.3 channels, which are expressed in lymphocytes, are a new therapeutic target for treating autoimmune disease. Consequently, Kv1.3 channel-inhibiting venom-derived peptides are a prospective resource for new drug discovery and clinical application. Area covered: Preclinical and clinical studies have produced a wealth of information on Kv1.3 channel-inhibiting venom-derived peptides, especially from venomous scorpions and sea anemones. This review highlights the advances in screening and design of these peptides with diverse structures and potencies. It focuses on representative strategies for improving peptide selectivity and discusses the preclinical research on those venom-derived peptides as well as their clinical developmental status. Expert opinion: Encouraging results indicate that peptides isolated from the venom of venomous animals are a large resource for discovering immunomodulators that act on Kv1.3 channels. Since the structural diversity of venom-derived peptides determines the variety of their pharmacological activities, the design and optimization of venom-peptides for improved Kv1.3 channel-specificity has been advanced through some representative strategies, such as peptide chemical modification, amino acid residue truncation and binding interface modulation. These advances should further accelerate research, development and the future clinical application of venom-derived peptides selectively targeting Kv1.3 channels.

HiRel - Reliability/availability integrated workstation tool

NASA Technical Reports Server (NTRS)

Bavuso, Salvatore J.; Dugan, Joanne B.

1992-01-01

The HiRel software tool is described and demonstrated by application to the mission avionics subsystem of the Advanced System Integration Demonstrations (ASID) system that utilizes the PAVE PILLAR approach. HiRel marks another accomplishment toward the goal of producing a totally integrated computer-aided design (CAD) workstation design capability. Since a reliability engineer generally represents a reliability model graphically before it can be solved, the use of a graphical input description language increases productivity and decreases the incidence of error. The graphical postprocessor module HARPO makes it possible for reliability engineers to quickly analyze huge amounts of reliability/availability data to observe trends due to exploratory design changes. The addition of several powerful HARP modeling engines provides the user with a reliability/availability modeling capability for a wide range of system applications all integrated under a common interactive graphical input-output capability.

A pluggable framework for parallel pairwise sequence search.

PubMed

Archuleta, Jeremy; Feng, Wu-chun; Tilevich, Eli

2007-01-01

The current and near future of the computing industry is one of multi-core and multi-processor technology. Most existing sequence-search tools have been designed with a focus on single-core, single-processor systems. This discrepancy between software design and hardware architecture substantially hinders sequence-search performance by not allowing full utilization of the hardware. This paper presents a novel framework that will aid the conversion of serial sequence-search tools into a parallel version that can take full advantage of the available hardware. The framework, which is based on a software architecture called mixin layers with refined roles, enables modules to be plugged into the framework with minimal effort. The inherent modular design improves maintenance and extensibility, thus opening up a plethora of opportunities for advanced algorithmic features to be developed and incorporated while routine maintenance of the codebase persists.

Advancement of the Wide-angle JEM-EUSO Optical System with Holographic and Fresnel Lenses

NASA Technical Reports Server (NTRS)

Takizawa, Y.; Adams, J.H.

2007-01-01

JEM-EUSO is a space mission to observe extremely high-energy cosmic rays, evolved from the previous design studies of EUSO. It is adjusted for the Japan Experiment Module (JEM) of the International Space Station (ISS). JEM-EUSO uses a wide-angle refractive telescope in near-ultraviolet wavelength region to observe from ISS the time-and-space-resolved atmospheric fluorescence images of the extensive air showers. The JEM-EUSO optics is re-designed after the ESA-Phase A studies to upgrade the light-collecting-power by using a new material CYTOP, and its overall light-collecting power is about 1.5 times higher than the ESA-Phase A baseline optics. We describe in this paper an optimized optics design that maximizes the sensitivity of JEM-EUSO, and the results of the optics manufacturing tests.

Thermoelectric Devices Advance Thermal Management

NASA Technical Reports Server (NTRS)

2007-01-01

Thermoelectric (TE) devices heat, cool, and generate electricity when a temperature differential is provided between the two module faces. In cooperation with NASA, Chico, California-based United States Thermoelectric Consortium Inc. (USTC) built a gas emissions analyzer (GEA) for combustion research. The GEA precipitated hydrocarbon particles, preventing contamination that would hinder precise rocket fuel analysis. The USTC research and design team uses patent-pending dimple, pin-fin, microchannel and microjet structures to develop and design heat dissipation devices on the mini-scale level, which not only guarantee high performance of products, but also scale device size from 1 centimeter to 10 centimeters. USTC continues to integrate the benefits of TE devices in its current line of thermal management solutions and has found the accessibility of NASA technical research to be a valuable, sustainable resource that has continued to positively influence its product design and manufacturing

Advanced Ion Exchange Softening. Training Module 2.212.4.77.

ERIC Educational Resources Information Center

McMullen, L. D.

This document is an instructional module package prepared in objective form for use by an instructor familiar with the operation of an ion exchange softening system. It includes objectives, an instructor guide, student handouts and transparency masters. This is the third level of a three module series. This module considers the theory of ion…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Yunhai

Similar to a super B-factory, a circular Higgs factory (CHF) will require strong focusing systems near the interaction points and a low-emittance lattice in the arcs to achieve a factory luminosity. At electron beam energy of 125 GeV, beamstrahlung effects during the collision pose an additional challenge to the collider design. In particular, a large momentum acceptance at the 2% level is necessary to retain an adequate beam lifetime. This turns out to be the most challenging aspect in the design of a CHF. In this paper, an example will be provided to illustrate the beam dynamics in a CHF,more » emphasizing the chromatic optics. Basic optical modules and advanced analysis will be presented. Most importantly, we will show that 2% momentum aperture is achievable.« less