Science.gov

Sample records for advanced quality control

  1. Rotorcraft flying qualities improvement using advanced control

    NASA Technical Reports Server (NTRS)

    Walker, D.; Postlethwaite, I.; Howitt, J.; Foster, N.

    1993-01-01

    We report on recent experience gained when a multivariable helicopter flight control law was tested on the Large Motion Simulator (LMS) at DRA Bedford. This was part of a study into the application of multivariable control theory to the design of full-authority flight control systems for high-performance helicopters. In this paper, we present some of the results that were obtained during the piloted simulation trial and from subsequent off-line simulation and analysis. The performance provided by the control law led to level 1 handling quality ratings for almost all of the mission task elements assessed, both during the real-time and off-line analysis.

  2. Implementation of a TMP Advanced Quality Control System at a Newsprint Manufacturing Plant

    SciTech Connect

    Sebastien Kidd

    2006-02-14

    This project provided for the implementation of an advanced, model predictive multi-variant controller that works with the mill that has existing distributed control system. The method provides real time and online predictive models and modifies control actions to maximize quality and minimize energy costs. Using software sensors, the system can predict difficult-to-measure quality and process variables and make necessary process control decisions to accurately control pulp quality while minimizing electrical usage. This method of control has allowed Augusta Newsprint Company to optimize the operation of its Thermo Mechanical Pulp mill for lower energy consumption and lower pulp quality variance.

  3. Advanced control technology and airworthiness flying qualities requirements

    NASA Technical Reports Server (NTRS)

    Snyder, C. T.

    1976-01-01

    Flying quality requirements are specified in terms of the complete pilot-airframe-systems loop, the task, and the environment. Results from a study of flying qualities are reported. A review of the treatment of failure cases in various flying quality requirements is presented along with a description of the methods used and relevant lessons learned from recent Autoland certification programs.

  4. Advanced terahertz techniques for quality control and counterfeit detection

    NASA Astrophysics Data System (ADS)

    Ahi, Kiarash; Anwar, Mehdi

    2016-04-01

    This paper reports our invented methods for detection of counterfeit electronic. These versatile techniques are also handy in quality control applications. Terahertz pulsed laser systems are capable of giving the material characteristics and thus make it possible to distinguish between the materials used in authentic components and their counterfeit clones. Components with material defects can also be distinguished in section in this manner. In this work different refractive indices and absorption coefficients were observed for counterfeit components compared to their authentic counterparts. Existence of unexpected ingredient materials was detected in counterfeit components by Fourier Transform analysis of the transmitted terahertz pulse. Thicknesses of different layers are obtainable by analyzing the reflected terahertz pulse. Existence of unexpected layers is also detectable in this manner. Recycled, sanded and blacktopped counterfeit electronic components were detected as a result of these analyses. Counterfeit ICs with die dislocations were detected by depicting the terahertz raster scanning data in a coordinate plane which gives terahertz images. In the same manner, raster scanning of the reflected pulse gives terahertz images of the surfaces of the components which were used to investigate contaminant materials and sanded points on the surfaces. The results of the later technique, reveals the recycled counterfeit components.

  5. Advanced Quality Control System for the Thermomechanical Pulping Process Improves Quality and Reduces Energy Costs for Augusta Newsprint

    SciTech Connect

    Not Available

    2002-02-01

    In July 2001, the Augusta Newsprint Company partnered with Invensys' Pacific Simulation group to implement an advanced quality control (AQC) solution for the thermomechanical pulping (TMP) process at Augusta Newsprint's Augusta, Georgia, site. The goal of the project is to decrease energy and raw material costs while maintaining final pulp quality. The project involves coordinating AQC in 3 areas of the paper mill to reduce the amount of energy required for manufacturing. In addition, a time-of-day production (TODP) feature will use current power market pricing data to adjust production rates in the pulping operation to minimize the average cost of purchased energy. The AQC implementation is currently in progress.

  6. Motion-base simulator results of advanced supersonic transport handling qualities with active controls

    NASA Technical Reports Server (NTRS)

    Feather, J. B.; Joshi, D. S.

    1981-01-01

    Handling qualities of the unaugmented advanced supersonic transport (AST) are deficient in the low-speed, landing approach regime. Consequently, improvement in handling with active control augmentation systems has been achieved using implicit model-following techniques. Extensive fixed-based simulator evaluations were used to validate these systems prior to tests with full motion and visual capabilities on a six-axis motion-base simulator (MBS). These tests compared the handling qualities of the unaugmented AST with several augmented configurations to ascertain the effectiveness of these systems. Cooper-Harper ratings, tracking errors, and control activity data from the MBS tests have been analyzed statistically. The results show the fully augmented AST handling qualities have been improved to an acceptable level.

  7. Advances in Process Control.

    ERIC Educational Resources Information Center

    Morrison, David L.; And Others

    1982-01-01

    Advances in electronics and computer science have enabled industries (pulp/paper, iron/steel, petroleum/chemical) to attain better control of their processes with resulting increases in quality, productivity, profitability, and compliance with government regulations. (JN)

  8. Advanced Quality Control Theory for Training and Education: A Guide to Optimizing Training and Education Efforts

    ERIC Educational Resources Information Center

    Heppler, Brad

    2008-01-01

    This is a book about quality and how to control quality through deliberate actions on the part of the professionals developing and implementing the instances of instruction available at an organization. Quality control theory favors no particular learning philosophy and is only directed towards aspects of how, what, where and when measurements are…

  9. Land Surface Microwave Emissivities Derived from AMSR-E and MODIS Measurements with Advanced Quality Control

    NASA Technical Reports Server (NTRS)

    Moncet, Jean-Luc; Liang, Pan; Galantowicz, John F.; Lipton, Alan E.; Uymin, Gennady; Prigent, Catherine; Grassotti, Christopher

    2011-01-01

    A microwave emissivity database has been developed with data from the Advanced Microwave Scanning Radiometer-EOS (AMSR-E) and with ancillary land surface temperature (LST) data from the Moderate Resolution Imaging Spectroradiometer (MODIS) on the same Aqua spacecraft. The primary intended application of the database is to provide surface emissivity constraints in atmospheric and surface property retrieval or assimilation. An additional application is to serve as a dynamic indicator of land surface properties relevant to climate change monitoring. The precision of the emissivity data is estimated to be significantly better than in prior databases from other sensors due to the precise collocation with high-quality MODIS LST data and due to the quality control features of our data analysis system. The accuracy of the emissivities in deserts and semi-arid regions is enhanced by applying, in those regions, a version of the emissivity retrieval algorithm that accounts for the penetration of microwave radiation through dry soil with diurnally varying vertical temperature gradients. These results suggest that this penetration effect is more widespread and more significant to interpretation of passive microwave measurements than had been previously established. Emissivity coverage in areas where persistent cloudiness interferes with the availability of MODIS LST data is achieved using a classification-based method to spread emissivity data from less-cloudy areas that have similar microwave surface properties. Evaluations and analyses of the emissivity products over homogeneous snow-free areas are presented, including application to retrieval of soil temperature profiles. Spatial inhomogeneities are the largest in the vicinity of large water bodies due to the large water/land emissivity contrast and give rise to large apparent temporal variability in the retrieved emissivities when satellite footprint locations vary over time. This issue will be dealt with in the future by

  10. Flight evaluations of the effect of advanced control systems and displays on the handling qualities of a general aviation airplane.

    NASA Technical Reports Server (NTRS)

    Loschke, P. C.; Barber, M. R.; Jarvis, C. R.; Enevoldson, E. K.

    1972-01-01

    Flight tests have shown that, by means of improved displays and advanced control systems, it is possible to transform a typical light airplane into a flying machine that borders on being perfect from a handling-qualities standpoint. A flight-director display and an attitude-command control system used in combination transformed a vehicle with poor handling qualities during ILS approaches in turbulent air into a vehicle with extremely good handling qualities. The attitude-command control system also improved the ride qualities of the airplane. A rate-command control system was less beneficial than an attitude-command control system. Although this paper deals primarily with general aviation aircraft, the results presented pertain to other types of aircraft. Short-takeoff-and-landing (STOL) aircraft would be a natural application of the control systems because, as a result of their low speeds, they encounter many of the handling-qualities problems noted on light aircraft. The improved ride qualities should be of interest to all airline operations, and for STOL aircraft in particular, because of their prolonged exposure to low-altitude turbulence.

  11. Advanced feedback control of indoor air quality using real-time computational fluid dynamics

    SciTech Connect

    Ratnam, E.; Campbell, T.; Bradley, R.

    1998-10-01

    This paper describes the partial implementation of a novel method of controlling indoor air quality (IAQ) for critical applications. The proposed method uses a numerical modeling technique known as computational fluid dynamics (CFD) for modeling the effect of variable ventilation rates for intelligent and rapid control of air contamination in space. This paper describes how a CFD model is made to run in real time linked to a feedback control loop. The technique was simulated in a graphical programming language. The simulation results indicate that a quasi-transient potential flow CFD model is a viable technique for feedback control of IAQ, and it is currently being implemented in an experimental validation.

  12. The space shuttle advanced solid rocket motor: Quality control and testing

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Congressional committees that authorize the activities of NASA requested that the National Research Council (NRC) review the testing and quality assurance programs for the Advanced Solid Rocket Motor (ASRM) program. The proposed ASRM design incorporates numerous features that are significant departures from the Redesigned Solid Rocket Motor (RSRM). The NRC review concentrated mainly on these features. Primary among these are the steel case material, welding rather than pinning of case factory joints, a bolted field joint designed to close upon firing the rocket, continuous mixing and casting of the solid propellant in place of the current batch processes, use of asbestos-free insulation, and a lightweight nozzle. The committee's assessment of these and other features of the ASRM are presented in terms of their potential impact on flight safety.

  13. Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

    PubMed Central

    Koehl, U.; Kalberer, C.; Spanholtz, J.; Lee, D. A.; Miller, J. S.; Cooley, S.; Lowdell, M.; Uharek, L.; Klingemann, H.; Curti, A.; Leung, W.; Alici, E.

    2016-01-01

    ABSTRACT Natural killer (NK) cells are increasingly used in clinical studies in order to treat patients with various malignancies. The following review summarizes platform lectures and 2013–2015 consortium meetings on manufacturing and clinical use of NK cells in Europe and United States. A broad overview of recent pre-clinical and clinical results in NK cell therapies is provided based on unstimulated, cytokine-activated, as well as genetically engineered NK cells using chimeric antigen receptors (CAR). Differences in donor selection, manufacturing and quality control of NK cells for cancer immunotherapies are described and basic recommendations are outlined for harmonization in future NK cell studies. PMID:27141397

  14. Advanced Wavefront Control Techniques

    SciTech Connect

    Olivier, S S; Brase, J M; Avicola, K; Thompson, C A; Kartz, M W; Winters, S; Hartley, R; Wihelmsen, J; Dowla, F V; Carrano, C J; Bauman, B J; Pennington, D M; Lande, D; Sawvel, R M; Silva, D A; Cooke, J B; Brown, C G

    2001-02-21

    Programs at LLNL that involve large laser systems--ranging from the National Ignition Facility to new tactical laser weapons--depend on the maintenance of laser beam quality through precise control of the optical wavefront. This can be accomplished using adaptive optics, which compensate for time-varying aberrations that are often caused by heating in a high-power laser system. Over the past two decades, LLNL has developed a broad capability in adaptive optics technology for both laser beam control and high-resolution imaging. This adaptive optics capability has been based on thin deformable glass mirrors with individual ceramic actuators bonded to the back. In the case of high-power lasers, these adaptive optics systems have successfully improved beam quality. However, as we continue to extend our applications requirements, the existing technology base for wavefront control cannot satisfy them. To address this issue, this project studied improved modeling tools to increase our detailed understanding of the performance of these systems, and evaluated novel approaches to low-order wavefront control that offer the possibility of reduced cost and complexity. We also investigated improved beam control technology for high-resolution wavefront control. Many high-power laser systems suffer from high-spatial-frequency aberrations that require control of hundreds or thousands of phase points to provide adequate correction. However, the cost and size of current deformable mirrors can become prohibitive for applications requiring more than a few tens of phase control points. New phase control technologies are becoming available which offer control of many phase points with small low-cost devices. The goal of this project was to expand our wavefront control capabilities with improved modeling tools, new devices that reduce system cost and complexity, and extensions to high spatial and temporal frequencies using new adaptive optics technologies. In FY 99, the second year of

  15. Advancements in analyzing food quality

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This editorial provides insight on investigations regarding advancement in the application of technology and it’s advancement to food quality. The discussion elaborates on the advantages of recent analytical technologies and techniques, along with their impact on food safety, characterization of its...

  16. Automated, Miniaturized and Integrated Quality Control-on-Chip (QC-on-a-Chip) for Advanced Cell Therapy Applications

    NASA Astrophysics Data System (ADS)

    Wartmann, David; Rothbauer, Mario; Kuten, Olga; Barresi, Caterina; Visus, Carmen; Felzmann, Thomas; Ertl, Peter

    2015-09-01

    The combination of microfabrication-based technologies with cell biology has laid the foundation for the development of advanced in vitro diagnostic systems capable of evaluating cell cultures under defined, reproducible and standardizable measurement conditions. In the present review we describe recent lab-on-a-chip developments for cell analysis and how these methodologies could improve standard quality control in the field of manufacturing cell-based vaccines for clinical purposes. We highlight in particular the regulatory requirements for advanced cell therapy applications using as an example dendritic cell-based cancer vaccines to describe the tangible advantages of microfluidic devices that overcome most of the challenges associated with automation, miniaturization and integration of cell-based assays. As its main advantage lab-on-a-chip technology allows for precise regulation of culturing conditions, while simultaneously monitoring cell relevant parameters using embedded sensory systems. State-of-the-art lab-on-a-chip platforms for in vitro assessment of cell cultures and their potential future applications for cell therapies and cancer immunotherapy are discussed in the present review.

  17. Delayed coker fractionator advanced control

    SciTech Connect

    Jaisinghani, R.; Minter, B. ); Tica, A.; Puglesi, A.; Ojeda, R. )

    1993-08-01

    In a delayed coking process, as coke drum switches are made, rapid changes occur in both the fractionator feed rate and composition. With conventional control, it is not unusual to see long transient behavior of large swings in both quality and flowrates of coker gas oils. This can extract a heavy economic toll, not only in coker operation, but in the operation of downstream units as the upset is propagated. An advanced process control application (APC) was recently implemented on the coker fractionator at the Yacimentos Petroliferos Fiscales (YPF), Lujan de Cuyo Refinery, in Mendoza, Argentina. This coker fractionator control design was unique as it handled two different operating objectives: control of product qualities via tower temperature profile during normal operation and control of gas oil product flow ratio during drum switch. This combination of control objectives in one multivariable predictive control program was achieved by including special logic to decouple the individual tuning requirements. Also, additional logic was included to unambiguously detect and identify drum switch and drum steam out as discrete events within 30 seconds of their actual occurrence. These discrete events were then used as disturbance variables to minimize fractionator transient behavior. As a performance measure, the overhead temperature was controlled within 2 C to 2.5 C of its target, gas oil flows were stabilized during drum switches and steam generation via pump around was maximized. Overall, implementing advanced control for the delayed coker fractionator resulted in substantial benefits from product quality control, product flow control and minimized energy consumption.

  18. Advanced Aerodynamic Control Effectors

    NASA Technical Reports Server (NTRS)

    Wood, Richard M.; Bauer, Steven X. S.

    1999-01-01

    A 1990 research program that focused on the development of advanced aerodynamic control effectors (AACE) for military aircraft has been reviewed and summarized. Data are presented for advanced planform, flow control, and surface contouring technologies. The data show significant increases in lift, reductions in drag, and increased control power, compared to typical aerodynamic designs. The results presented also highlighted the importance of planform selection in the design of a control effector suite. Planform data showed that dramatic increases in lift (greater than 25%) can be achieved with multiple wings and a sawtooth forebody. Passive porosity and micro drag generator control effector data showed control power levels exceeding that available from typical effectors (moving surfaces). Application of an advanced planform to a tailless concept showed benefits of similar magnitude as those observed in the generic studies.

  19. Quality Leadership and Quality Control

    PubMed Central

    Badrick, Tony

    2003-01-01

    Different quality control rules detect different analytical errors with varying levels of efficiency depending on the type of error present, its prevalence and the number of observations. The efficiency of a rule can be gauged by inspection of a power function graph. Control rules are only part of a process and not an end in itself; just as important are the trouble-shooting systems employed when a failure occurs. 'Average of patient normals' may develop as a usual adjunct to conventional quality control serum based programmes. Acceptable error can be based on various criteria; biological variation is probably the most sensible. Once determined, acceptable error can be used as limits in quality control rule systems. A key aspect of an organisation is leadership, which links the various components of the quality system. Leadership is difficult to characterise but its key aspects include trust, setting an example, developing staff and critically setting the vision for the organisation. Organisations also have internal characteristics such as the degree of formalisation, centralisation, and complexity. Medical organisations can have internal tensions because of the dichotomy between the bureaucratic and the shadow medical structures. PMID:18568046

  20. QUALITY CONTROLS FOR PCR

    EPA Science Inventory

    The purpose of this presentation is to present an overview of the quality control (QC) sections of a draft EPA document entitled, "Quality Assurance/Quality Control Guidance for Laboratories Performing PCR Analyses on Environmental Samples." This document has been prepared by th...

  1. Recent advances in the compound-oriented and pattern-oriented approaches to the quality control of herbal medicines

    PubMed Central

    Zeng, Zhongda; Chau, Foo-tim; Chan, Hoi-yan; Cheung, Chui-yee; Lau, Tsui-yan; Wei, Shuiyin; Mok, Daniel Kam-wah; Chan, Chi-on; Liang, Yizeng

    2008-01-01

    The current approaches to the quality control of herbal medicines are either compound-oriented or pattern-oriented, the former targeting specific components with some known chemical properties and the latter targeting all detectable components. The marker approach uses specific chemical compounds with known molecular structures, while the multi-compound approach uses both chemical compounds with known structures and those with partial chemical information e.g. retention times, mass spectra and ultraviolet spectra. Apart from chromatographic techniques, new techniques such as oscillating and electrochemistry fingerprints have been developed for quality control. Chemometric resolution methods are widely used for component deconvolution and data comparison. Pattern recognition techniques are used for authentication of herbal medicines. PMID:18680568

  2. [Quality control dose calibrators].

    PubMed

    Montoza Aguado, M; Delgado García, A; Ramírez Navarro, A; Salgado García, C; Muros de Fuentes, M A; Ortega Lozano, S; Bellón Guardia, M E; Llamas Elvira, J M

    2004-01-01

    We have reviewed the legislation about the quality control of dose calibrator. The importance of verifying the correct work of these instruments, is fundamental in daily practice of radiopharmacy and nuclear medicine. The Spanish legislation establishes to include these controls as part of the quality control of radiopharmaceuticals, and the program of quality assurance in nuclear medicine. We have reviewed guides and protocols from international eminent organizations, summarizing the recommended tests and periodicity of them. PMID:15625064

  3. Radiographic quality control devices.

    PubMed

    2000-04-01

    In this study, we evaluate eight radiographic quality control (QC) devices, which noninvasively measure the output from a variety of diagnostic x-ray production systems. When used as part of a quality assurance (QA) program, radiographic QC devices help ensure that x-ray equipment is working within acceptable limits. This in turn helps ensure that high-quality images are achieved with appropriate radiation doses and that resources are used efficiently (for example, by minimizing the number of repeat exposures required). Our testing focused on the physical performance, ease of use, and service and maintenance characteristics that affect the use of these devices for periodic, routine measurements of x-ray system parameters. We found that all the evaluated models satisfactorily measure all the parameters normally needed for a QA program. However, we did identify a number of differences among the models--particularly in the range of exposure levels that can be effectively measured and the ease of use. Three models perform well for a variety of applications and are very easy to use; we rate them Preferred. Three additional models have minor limitations but otherwise perform well; we rate them Acceptable. We recommend against purchasing two models because, although each performs acceptably for most applications, neither model can measure low levels of radiation. This Evaluation covers devices designed to measure the output of x-ray tubes noninvasively. These devices, called radiographic quality control (QC) devices, or QC meters, are typically used by medical physicists, x-ray engineers, biomedical engineers, and suitably trained radiographic technologists to make QC measurements. We focus on the use of these devices as part of an overall quality assurance (QA) program. We have not evaluated their use for other applications, such as acceptance testing. To be included in this study, a device must be able to measure the exposure- and kVp-related characteristics of most x

  4. Instrument Quality Control.

    PubMed

    Jayakody, Chatura; Hull-Ryde, Emily A

    2016-01-01

    Well-defined quality control (QC) processes are used to determine whether a certain procedure or action conforms to a widely accepted standard and/or set of guidelines, and are important components of any laboratory quality assurance program (Popa-Burke et al., J Biomol Screen 14: 1017-1030, 2009). In this chapter, we describe QC procedures useful for monitoring the accuracy and precision of laboratory instrumentation, most notably automated liquid dispensers. Two techniques, gravimetric QC and photometric QC, are highlighted in this chapter. When used together, these simple techniques provide a robust process for evaluating liquid handler accuracy and precision, and critically underpin high-quality research programs. PMID:27316990

  5. Advanced automation in space shuttle mission control

    NASA Technical Reports Server (NTRS)

    Heindel, Troy A.; Rasmussen, Arthur N.; Mcfarland, Robert Z.

    1991-01-01

    The Real Time Data System (RTDS) Project was undertaken in 1987 to introduce new concepts and technologies for advanced automation into the Mission Control Center environment at NASA's Johnson Space Center. The project's emphasis is on producing advanced near-operational prototype systems that are developed using a rapid, interactive method and are used by flight controllers during actual Shuttle missions. In most cases the prototype applications have been of such quality and utility that they have been converted to production status. A key ingredient has been an integrated team of software engineers and flight controllers working together to quickly evolve the demonstration systems.

  6. Project T.E.A.M. (Technical Education Advancement Modules). Advanced Statistical Process Control.

    ERIC Educational Resources Information Center

    Dunlap, Dale

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 20-hour advanced statistical process control (SPC) and quality improvement course designed to develop the following competencies: (1) understanding quality systems; (2) knowing the process; (3) solving quality problems; and (4)…

  7. Japanese Quality Control Circles.

    ERIC Educational Resources Information Center

    Nishiyama, Kazuo

    In recent years, United States scholars with an interest in international business and organizational communication have begun to notice the success of Japanese "quality control circles." These are small groups, usually composed of seven to ten workers, who are organized at the production levels within most large Japanese factories. A typical…

  8. SIMBAD Quality-Control

    NASA Astrophysics Data System (ADS)

    Lesteven, Soizick

    1993-01-01

    Taking into consideration the amount and the complexity of SIMBAD data, it is necessary to use automatic methods to control and assure the quality of the SIMBAD database. One possibility is to apply multivariate data analysis to the content of documents related to astronomical data. The method and first results are presented.

  9. Vgi Quality Control

    NASA Astrophysics Data System (ADS)

    Fonte, C. C.; Bastin, L.; Foody, G.; Kellenberger, T.; Kerle, N.; Mooney, P.; Olteanu-Raimond, A.-M.; See, L.

    2015-08-01

    This paper presents a framework for considering quality control of volunteered geographic information (VGI). Different issues need to be considered during the conception, acquisition and post-acquisition phases of VGI creation. This includes items such as collecting metadata on the volunteer, providing suitable training, giving corrective feedback during the mapping process and use of control data, among others. Two examples of VGI data collection are then considered with respect to this quality control framework, i.e. VGI data collection by National Mapping Agencies and by the most recent Geo-Wiki tool, a game called Cropland Capture. Although good practices are beginning to emerge, there is still the need for the development and sharing of best practice, especially if VGI is to be integrated with authoritative map products or used for calibration and/or validation of land cover in the future.

  10. ADVANCED SULFUR CONTROL CONCEPTS

    SciTech Connect

    Apostolos A. Nikolopoulos; Santosh K. Gangwal; William J. McMichael; Jeffrey W. Portzer

    2003-01-01

    Conventional sulfur removal in integrated gasification combined cycle (IGCC) power plants involves numerous steps: COS (carbonyl sulfide) hydrolysis, amine scrubbing/regeneration, Claus process, and tail-gas treatment. Advanced sulfur removal in IGCC systems involves typically the use of zinc oxide-based sorbents. The sulfides sorbent is regenerated using dilute air to produce a dilute SO{sub 2} (sulfur dioxide) tail gas. Under previous contracts the highly effective first generation Direct Sulfur Recovery Process (DSRP) for catalytic reduction of this SO{sub 2} tail gas to elemental sulfur was developed. This process is currently undergoing field-testing. In this project, advanced concepts were evaluated to reduce the number of unit operations in sulfur removal and recovery. Substantial effort was directed towards developing sorbents that could be directly regenerated to elemental sulfur in an Advanced Hot Gas Process (AHGP). Development of this process has been described in detail in Appendices A-F. RTI began the development of the Single-step Sulfur Recovery Process (SSRP) to eliminate the use of sorbents and multiple reactors in sulfur removal and recovery. This process showed promising preliminary results and thus further process development of AHGP was abandoned in favor of SSRP. The SSRP is a direct Claus process that consists of injecting SO{sub 2} directly into the quenched coal gas from a coal gasifier, and reacting the H{sub 2}S-SO{sub 2} mixture over a selective catalyst to both remove and recover sulfur in a single step. The process is conducted at gasifier pressure and 125 to 160 C. The proposed commercial embodiment of the SSRP involves a liquid phase of molten sulfur with dispersed catalyst in a slurry bubble-column reactor (SBCR).

  11. Quality control review: implementing a scientifically based quality control system.

    PubMed

    Westgard, James O; Westgard, Sten A

    2016-01-01

    This review focuses on statistical quality control in the context of a quality management system. It describes the use of a 'Sigma-metric' for validating the performance of a new examination procedure, developing a total quality control strategy, selecting a statistical quality control procedure and monitoring ongoing quality on the sigma scale. Acceptable method performance is a prerequisite to the design and implementation of statistical quality control procedures. Statistical quality control can only monitor performance, and when properly designed, alert analysts to the presence of additional errors that occur because of unstable performance. A new statistical quality control planning tool, called 'Westgard Sigma Rules,' provides a simple and quick way for selecting control rules and the number of control measurements needed to detect medically important errors. The concept of a quality control plan is described, along with alternative adaptations of a total quality control plan and a risk-based individualized quality control plan. Finally, the ongoing monitoring of analytic performance and test quality are discussed, including determination of measurement uncertainty from statistical quality control data collected under intermediate precision conditions and bias determined from proficiency testing/external quality assessment surveys. A new graphical tool, called the Sigma Quality Assessment Chart, is recommended for demonstrating the quality of current examination procedures on the sigma scale. PMID:26150675

  12. Advances in infection control

    PubMed Central

    Marra, Alexandre Rodrigues

    2016-01-01

    ABSTRACT Several initiatives took place in recent years in relation to nosocomial infection control in order to increase patient safety. Some of these initiatives will be commented in this brief review. PMID:27074240

  13. The effect on quality of life of vitamin D administration for advanced cancer treatment (VIDAFACT study): protocol of a randomised controlled trial

    PubMed Central

    Martinez-Alonso, Montserrat; Dusso, Adriana; Ariza, Gemma; Nabal, Maria

    2014-01-01

    Introduction Vitamin D is related to resistance to chronic diseases, physiological parameters and functional measures. All of these relationships underscore the potential benefits of cholecalciferol or D3 (nutritional vitamin D) in cancer. This is the first study designed to obtain conclusive evidence on the effect of cholecalciferol in advanced patients with cancer. The main goal is to assess its effects on the patient's perceived quality of life. Cholecalciferol's impact on fatigue and physical performance, as well as its cost utility, will also be assessed. Methods and analysis A randomised triple-blind phase II/III placebo-controlled multicentre trial has been designed. Patients satisfying the inclusion and exclusion criteria will be randomly assigned to receive cholecalciferol or placebo. Eligible patients will be adults with a locally advanced or metastatic or inoperable solid cancer in palliative care, who have given signed informed consent and have matched inclusion and exclusion criteria. The randomisation will be based on a computer-generated procedure and centralised by the pharmacy service of the coordinating centre. The assigned treatment will be administered by the hospital's pharmacy to conceal group allocation for patients and healthcare providers. Cholecalciferol (4000 IU/day) or placebo, starting at day 15 and continuing up to day 42, will be added to palliative care treatment. Outpatient visits will be scheduled every 14 days. Ethics and dissemination Ethical approval was received from the Medical Ethical Commitee of the HUAV (CEIC-1169). Participants and their families will receive the research findings which will also be disseminated on local and national media, presented at national and international meetings of the specialty, and published in peer-reviewed scientific journals. Trial registration number EudraCT: 2013-003478-29. PMID:25552610

  14. Advanced flight control system study

    NASA Technical Reports Server (NTRS)

    Mcgough, J.; Moses, K.; Klafin, J. F.

    1982-01-01

    The architecture, requirements, and system elements of an ultrareliable, advanced flight control system are described. The basic criteria are functional reliability of 10 to the minus 10 power/hour of flight and only 6 month scheduled maintenance. A distributed system architecture is described, including a multiplexed communication system, reliable bus controller, the use of skewed sensor arrays, and actuator interfaces. Test bed and flight evaluation program are proposed.

  15. ADVANCED EMISSIONS CONTROL DEVELOPMENT PROGRAM

    SciTech Connect

    G.A. Farthing

    2001-02-06

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (HAPs, or air toxics) from coal-fired boilers. The project goal is to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESPs), fabric filters (baghouses), and wet flue gas desulfurization (WFGD) systems. Development work initially concentrated on the capture of trace metals, fine particulate, hydrogen chloride, and hydrogen fluoride. Recent work has focused almost exclusively on the control of mercury emissions.

  16. Advanced Emissions Control Development Program

    SciTech Connect

    G. A. Farthing; G. T. Amrhein; G. A. Kudlac; D. A. Yurchison; D. K. McDonald; M. G. Milobowski

    2001-03-31

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (HAPs, or air toxics) from coal-fired boilers. This objective is being met by identifying ways to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESPs), fabric filters (fabric filters), and wet flue gas desulfurization (wet FGD) systems. Development work initially concentrated on the capture of trace metals, hydrogen chloride, and hydrogen fluoride. Recent work has focused almost exclusively on the control of mercury emissions.

  17. Controlling air toxics through advanced coal preparation

    SciTech Connect

    Straszheim, W.E.; Buttermore, W.H.; Pollard, J.L.

    1995-11-01

    This project involves the assessment of advanced coal preparation methods for removing trace elements from coal to reduce the potential for air toxic emissions upon combustion. Scanning electron microscopy-based automated image analysis (SEM-AIA) and advanced washability analyses are being applied with state-of-the-art analytical procedures to predict the removal of elements of concern by advanced column flotation and to confirm the effectiveness of preparation on the quality of quantity of clean coal produced. Specific objectives are to maintain an acceptable recovery of combustible product, while improving the rejection of mineral-associated trace elements. Current work has focused on determining conditions for controlling column flotation system across its operating range and on selection and analysis of samples for determining trace element cleanability.

  18. SIMBAD quality-control

    NASA Technical Reports Server (NTRS)

    Lesteven, Soizick

    1992-01-01

    The astronomical database SIMBAD developed at the Centre de donnees astronomiques de Strasbourg presently contains 760,000 objects (stellar and non-stellar). It has the unique characteristic of being structured specifically for astronomical objects. All types of heterogeneous data (bibliographic references, measurements, and sets of identification) are connected with each object. The attributes that define quality of the database include the following. Reliability: cross-identification should not rely upon just exact values object coordinates. It also means that information attached to one simple object should be consistent. The existing data must be controlled in order to start with a reliable base and to cross-identify new data assuring the quality as data grows. Exhaustivity: delays between publication of new informations and their inclusion in the database should be as short as possible. The integrity of the database has to be maintained as data accumulates. Taking the amount of data into consideration and the rate of new data production, it is necessary to use automatic methods. One of the possibilities is to use multivariate data analysis. The factor-space is a n-dimensional relevancy space which is described by the n-axes representing a set of n subject matter headings; the words and phrases can be used to scale the axes and the documents are then a vector average of the terms within them. The application reported herein is based on the NASA-STI bibliographical database. The selected data concern astronomy, astrophysics, and space radiation (102,963 references from 1975 to 1991 included 8070 keywords). The F-space is built from this bibliographical data. By comparing the F-space position obtained from the NASA-STI keywords with the F-space position obtained from the SIMBAD references, the authors will be able to show whether it is possible to retrieve information with a restricted set of words only. If the comparison is valid, this will be a way to enter

  19. Advanced flight control system study

    NASA Technical Reports Server (NTRS)

    Hartmann, G. L.; Wall, J. E., Jr.; Rang, E. R.; Lee, H. P.; Schulte, R. W.; Ng, W. K.

    1982-01-01

    A fly by wire flight control system architecture designed for high reliability includes spare sensor and computer elements to permit safe dispatch with failed elements, thereby reducing unscheduled maintenance. A methodology capable of demonstrating that the architecture does achieve the predicted performance characteristics consists of a hierarchy of activities ranging from analytical calculations of system reliability and formal methods of software verification to iron bird testing followed by flight evaluation. Interfacing this architecture to the Lockheed S-3A aircraft for flight test is discussed. This testbed vehicle can be expanded to support flight experiments in advanced aerodynamics, electromechanical actuators, secondary power systems, flight management, new displays, and air traffic control concepts.

  20. Advanced gray rod control assembly

    DOEpatents

    Drudy, Keith J; Carlson, William R; Conner, Michael E; Goldenfield, Mark; Hone, Michael J; Long, Jr., Carroll J; Parkinson, Jerod; Pomirleanu, Radu O

    2013-09-17

    An advanced gray rod control assembly (GRCA) for a nuclear reactor. The GRCA provides controlled insertion of gray rod assemblies into the reactor, thereby controlling the rate of power produced by the reactor and providing reactivity control at full power. Each gray rod assembly includes an elongated tubular member, a primary neutron-absorber disposed within the tubular member said neutron-absorber comprising an absorber material, preferably tungsten, having a 2200 m/s neutron absorption microscopic capture cross-section of from 10 to 30 barns. An internal support tube can be positioned between the primary absorber and the tubular member as a secondary absorber to enhance neutron absorption, absorber depletion, assembly weight, and assembly heat transfer characteristics.

  1. General aviation fuel quality control

    NASA Technical Reports Server (NTRS)

    Poitz, H.

    1983-01-01

    Quality control measures for aviation gasoline, and some of the differences between quality control on avgas and mogas are discussed. One thing to keep in mind is that with motor gasoline you can always pull off to the side of the road. It's not so easy to do in an airplane. Consequently, there are reasons for having the tight specifications and the tight quality control measures on avgas as compared to motor gasoline.

  2. Advances in genomics for the improvement of quality in coffee.

    PubMed

    Tran, Hue Tm; Lee, L Slade; Furtado, Agnelo; Smyth, Heather; Henry, Robert J

    2016-08-01

    Coffee is an important crop that provides a livelihood to millions of people living in developing countries. Production of genotypes with improved coffee quality attributes is a primary target of coffee genetic improvement programmes. Advances in genomics are providing new tools for analysis of coffee quality at the molecular level. The recent report of a genomic sequence for robusta coffee, Coffea canephora, is a major development. However, a reference genome sequence for the genetically more complex arabica coffee (C. arabica) will also be required to fully define the molecular determinants controlling quality in coffee produced from this high quality coffee species. Genes responsible for control of the levels of the major biochemical components in the coffee bean that are known to be important in determining coffee quality can now be identified by association analysis. However, the narrow genetic base of arabica coffee suggests that genomics analysis of the wild relatives of coffee (Coffea spp.) may be required to find the phenotypic diversity required for effective association genetic analysis. The genomic resources available for the study of coffee quality are described and the potential for the application of next generation sequencing and association genetic analysis to advance coffee quality research are explored. © 2016 Society of Chemical Industry. PMID:26919810

  3. Advanced nuclear plant control complex

    DOEpatents

    Scarola, Kenneth; Jamison, David S.; Manazir, Richard M.; Rescorl, Robert L.; Harmon, Daryl L.

    1993-01-01

    An advanced control room complex for a nuclear power plant, including a discrete indicator and alarm system (72) which is nuclear qualified for rapid response to changes in plant parameters and a component control system (64) which together provide a discrete monitoring and control capability at a panel (14-22, 26, 28) in the control room (10). A separate data processing system (70), which need not be nuclear qualified, provides integrated and overview information to the control room and to each panel, through CRTs (84) and a large, overhead integrated process status overview board (24). The discrete indicator and alarm system (72) and the data processing system (70) receive inputs from common plant sensors and validate the sensor outputs to arrive at a representative value of the parameter for use by the operator during both normal and accident conditions, thereby avoiding the need for him to assimilate data from each sensor individually. The integrated process status board (24) is at the apex of an information hierarchy that extends through four levels and provides access at each panel to the full display hierarchy. The control room panels are preferably of a modular construction, permitting the definition of inputs and outputs, the man machine interface, and the plant specific algorithms, to proceed in parallel with the fabrication of the panels, the installation of the equipment and the generic testing thereof.

  4. Quality-controlled Subject Gateways: Definitions, Typologies, Empirical Overview.

    ERIC Educational Resources Information Center

    Koch, Traugott

    2000-01-01

    "Quality-controlled subject gateways" are Internet services which apply quality measures to support systematic resource discovery. A main goal is to provide high quality subject access through indexing resources using controlled vocabularies and by offering a deep classification structure for advanced searching and browsing. Provides an empirical…

  5. Quality control on the frontier

    PubMed Central

    Paszkiewicz, Konrad H.; Farbos, Audrey; O'Neill, Paul; Moore, Karen

    2014-01-01

    In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality control information, as well as more specific metrics for genomic and transcriptomic libraries run on Illumina platforms. PMID:24904650

  6. Advanced Emissions Control Development Program

    SciTech Connect

    A.P.Evans; K.E. Redinger; M.J. Holmes

    1998-04-01

    The objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. Ideally, the project aim is to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESPS), fabric filters (baghouse), and wet flue gas desulfurization. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate and hydrogen chloride. Following the construction and evaluation of a representative air toxics test facility in Phase I, Phase II focused on the evaluation of mercury and several other air toxics emissions. The AECDP is jointly funded by the United States Department of Energy's Federal Energy Technology Center (DOE), the Ohio Coal Development Office within the Ohio Department of Development (oCDO), and Babcock& Wilcox-a McDermott company (B&W).

  7. Protein Quality Control and Metabolism: Bidirectional Control in the Heart

    PubMed Central

    Wang, Zhao V.; Hill, Joseph A.

    2015-01-01

    The prevalence of heart disease, especially heart failure, continues to increase, and cardiovascular disease remains the leading cause of death worldwide. As cardiomyocytes are essentially irreplaceable, protein quality control is pivotal to cellular homeostasis and, ultimately, cardiac performance. Three evolutionarily conserved mechanisms – autophagy, the unfolded protein response, and the ubiquitin-proteasome system– act in concert to degrade misfolded proteins and eliminate defective organelles. Recent advances have revealed that these mechanisms are intimately associated with cellular metabolism. Going forward, comprehensive understanding of the role of protein quality control mechanisms in cardiac pathology will require integration of metabolic pathways and metabolic control. PMID:25651176

  8. Quality assurance/quality control manual; National Water Quality Laboratory

    USGS Publications Warehouse

    Pritt, J.W.; Raese, J.W.

    1995-01-01

    Quality-control practices are established for the operation of the U.S. Geological Survey's National Water Quality Laboratory. These practices specify how samples are preserved, shipped, and analyzed in the Laboratory. This manual documents the practices that are currently (1995) used in the Laboratory.

  9. Quality Control by Artificial Vision

    SciTech Connect

    Lam, Edmond Y.; Gleason, Shaun Scott; Niel, Kurt S.

    2010-01-01

    Computational technology has fundamentally changed many aspects of our lives. One clear evidence is the development of artificial-vision systems, which have effectively automated many manual tasks ranging from quality inspection to quantitative assessment. In many cases, these machine-vision systems are even preferred over manual ones due to their repeatability and high precision. Such advantages come from significant research efforts in advancing sensor technology, illumination, computational hardware, and image-processing algorithms. Similar to the Special Section on Quality Control by Artificial Vision published two years ago in Volume 17, Issue 3 of the Journal of Electronic Imaging, the present one invited papers relevant to fundamental technology improvements to foster quality control by artificial vision, and fine-tuned the technology for specific applications. We aim to balance both theoretical and applied work pertinent to this special section theme. Consequently, we have seven high-quality papers resulting from the stringent peer-reviewing process in place at the Journal of Electronic Imaging. Some of the papers contain extended treatment of the authors work presented at the SPIE Image Processing: Machine Vision Applications conference and the International Conference on Quality Control by Artificial Vision. On the broad application side, Liu et al. propose an unsupervised texture image segmentation scheme. Using a multilayer data condensation spectral clustering algorithm together with wavelet transform, they demonstrate the effectiveness of their approach on both texture and synthetic aperture radar images. A problem related to image segmentation is image extraction. For this, O'Leary et al. investigate the theory of polynomial moments and show how these moments can be compared to classical filters. They also show how to use the discrete polynomial-basis functions for the extraction of 3-D embossed digits, demonstrating superiority over Fourier

  10. Quality control of a teleradiology system

    NASA Astrophysics Data System (ADS)

    Lyche, David K.; Willis, Charles E.; Williamson, Morgan P.; Suitor, Charles T.; Romlein, John R.

    1996-04-01

    Teleradiology is being implemented in the U.S. military. Soft-copy reading of computed radiology (CR) images and film-digitizer (FD) images are becoming a common practice. The Medical Diagnostic Imaging Support (MDIS) Office at the Medical Advanced Technology Management Office (MATMO), Fort Detrick, Maryland, installed an 'off-the-shelf' DICOM teleradiology system by which CR images and FD images acquired at Hickam Air Force Base (AFB), Hawaii, are transmitted electronically over a T-1 telecommunications line to Tripler Army Medical Center (TAMC), Hawaii. The goal was to provide a diagnostic quality teleradiology system to the military services to extend the expertise and training of physicians to remote sites. In order to guarantee a diagnostic quality image throughout the system, a rigid set of quality control standards had to be designed and implemented. This poster presents the results of a successful teleradiology implementation where quality control is maintained throughout the imaging chain.

  11. Advanced Emission Control Development Program.

    SciTech Connect

    Evans, A.P.

    1997-12-31

    Babcock & Wilcox (B&W) is conducting a five-year project aimed at the development of practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (commonly called air toxics) from coal-fired electric utility plants. The need for air toxic emissions controls may arise as the U. S. Environmental Protection Agency proceeds with implementation of Title III of the Clean Air Act Amendment (CAAA) of 1990. Data generated during the program will provide utilities with the technical and economic information necessary to reliably evaluate various air toxics emissions compliance options such as fuel switching, coal cleaning, and flue gas treatment. The development work is being carried out using B&W`s new Clean Environment Development Facility (CEDF) wherein air toxics emissions control strategies can be developed under controlled conditions, and with proven predictability to commercial systems. Tests conducted in the CEDF provide high quality, repeatable, comparable data over a wide range of coal properties, operating conditions, and emissions control systems. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate, and the inorganic species hydrogen chloride and hydrogen fluoride.

  12. Advanced Emissions Control Development Program

    SciTech Connect

    Evans, A P

    1998-12-03

    Babcock & Wilcox (B&W) is conducting a five-year project aimed at the development of practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (commonly called air toxics) from coal-fired electric utility plants. The need for air toxic emissions controls may arise as the U. S. Environmental Protection Agency proceeds with implementation of Title III of the Clean Air Act Amendment (CAAA) of 1990. Data generated during the program will provide utilities with the technical and economic information necessary to reliably evaluate various air toxics emissions compliance options such as fuel switching, coal cleaning, and flue gas treatment. The development work is being carried out using B&W's new Clean Environment Development Facility (CEDF) wherein air toxics emissions control strategies can be developed under controlled conditions, and with proven predictability to commercial systems. Tests conducted in the CEDF provide high quality, repeatable, comparable data over a wide range of coal properties, operating conditions, and emissions control systems. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate, and the inorganic species hydrogen chloride and hydrogen fluoride.

  13. Advanced Emissions Control Development Program

    SciTech Connect

    M. J. Holmes

    1998-12-03

    McDermott Technology, Inc. (MTI) is conducting a five-year project aimed at the development of practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (commonly called air toxics) from coal-fired electric utility plants. The need for air toxic emissions controls may arise as the U. S. Environmental Protection Agency proceeds with implementation of Title III of the Clean Air Act Amendment (CAAA) of 1990. Data generated during the program will provide utilities with the technical and economic information necessary to reliably evaluate various air toxics emissions compliance options such as fuel switching, coal cleaning, and flue gas treatment. The development work is being carried out using the Clean Environment Development Facility (CEDF) wherein air toxics emissions control strategies can be developed under controlled conditions, and with proven predictability to commercial systems. Tests conducted in the CEDF provide high quality, repeatable, comparable data over a wide range of coal properties, operating conditions, and emissions control systems. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate, and hydrogen chloride and hydrogen fluoride.

  14. Advanced Emissions Control Development Program

    SciTech Connect

    A. P. Evans

    1998-12-03

    McDermott Technology, Inc. (MTI) is conducting a five-year project aimed at the development of practical, cost-effective strategies for reducing the emissions of hazardous air pollutants (commonly called air toxics) from coal-fired electric utility plants. The need for air toxic emissions controls may arise as the U. S. Environmental Protection Agency proceeds with implementation of Title III of the Clean Air Act Amendment (CAAA) of 1990. Data generated during the program will provide utilities with the technical and economic information necessary to reliably evaluate various air toxics emissions compliance options such as fuel switching, coal cleaning, and flue gas treatment. The development work is being carried out using the Clean Environment Development Facility (CEDF) wherein air toxics emissions control strategies can be developed under controlled conditions, and with proven predictability to commercial systems. Tests conducted in the CEDF provide high quality, repeatable, comparable data over a wide range of coal properties, operating conditions, and emissions control systems. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate, and the inorganic species, hydrogen chloride and hydrogen fluoride.

  15. Network-based production quality control

    NASA Astrophysics Data System (ADS)

    Kwon, Yongjin; Tseng, Bill; Chiou, Richard

    2007-09-01

    This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

  16. Advanced fiber optic face plate quality detector design

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Su, Liping; Zhao, Jingxia

    2010-10-01

    A fiber optic face plate is defined by a plurality of fibers of transparent material that are fused and compressed together to transmit an image from one end to another end. Fiber optic face plates exhibit utility in the image intensifiers, cathoderay tubes, and other media displays. In this paper, the design of an advanced fiber optic face plate quality detector is presented. Modern optoelectronic imaging techniques are being used to form fiber optic plate transmission images that are suitable for analyzing the quality parameters of fiber optic face plate. The diffusing light from a halogen lamp is condensed by condenser lens then through a fiber optic face plate, a set of lenses are used to magnify the transmission image, a computer controls a long linear CCD to scan the transmission image, a data grabber captures the CCD's output data and the computer transforms the data into frame image for further analysis. Digital image processing techniques are adopted to analyze the transmission image to obtain the required quality parameters. The image analysis software combines the API that a company provided and programed API is used to acquire the quality parameter that a relevant criteria required. With the long linear CCD scanning and image analysis being computerized, it accomplishes the detection of quality parameters of fiber optic face plates automaticly. The detector can replace the manual detection method and can be widely used for the quality detection of fiber optic face plate. Manufacturers of fiber optic face plates can benefit from the detector for quality control.

  17. Protein quality control in the bacterial periplasm.

    PubMed

    Merdanovic, Melisa; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael

    2011-01-01

    Protein quality control involves sensing and treatment of defective or incomplete protein structures. Misfolded or mislocalized proteins trigger dedicated signal transduction cascades that upregulate the production of protein quality-control factors. Corresponding proteases and chaperones either degrade or repair damaged proteins, thereby reducing the level of aggregation-prone molecules. Because the periplasm of gram-negative bacteria is particularly exposed to environmental changes and respective protein-folding stresses connected with the presence of detergents, low or high osmolarity of the medium, elevated temperatures, and the host's immune response, fine-tuned protein quality control systems are essential for survival under these unfavorable conditions. This review discusses recent advances in the identification and characterization of the key cellular factors and the emerging general principles of the underlying molecular mechanisms. PMID:21639788

  18. Post-translational Modification and Quality Control

    PubMed Central

    Wang, Xuejun; Pattison, J. Scott; Su, Huabo

    2013-01-01

    Protein quality control (PQC) functions to minimize the level and toxicity of misfolded proteins in the cell. PQC is performed by intricate collaboration among chaperones and target protein degradation. The latter is carried out primarily by the ubiquitin-proteasome system and perhaps autophagy. Terminally misfolded proteins that are not timely removed tend to form aggregates. Their clearance requires macroautophagy. Macroautophagy serves in intracellular quality control also by selectively segregating defective organelles (e.g., mitochondria) and targeting them for degradation by the lysosome. Inadequate PQC is observed in a large subset of failing human hearts with a variety of etiologies and its pathogenic role has been experimentally demonstrated. Multiple post-translational modifications (PTMs) can occur to substrate proteins and/or PQC machineries, promoting or hindering the removal of the misfolded proteins. This article highlights recent advances in PTMs-mediated regulation of intracellular quality control mechanisms and its known involvement in cardiac pathology. PMID:23329792

  19. The advanced flame quality indicator system

    SciTech Connect

    Oman, R.; Rossi, M.J.; Calia, V.S.; Davis, F.L.; Rudin, A.

    1997-09-01

    By combining oil tank monitoring, systems diagnostics and flame quality monitoring in an affordable system that communicates directly with dealers by telephone modem, Insight Technologies offers new revenue opportunities and the capability for a new order of customer relations to oil dealers. With co-sponsorship from New York State Energy Research and Development Authority, we have incorporated several valuable functions to a new product based on the original Flame Quality Indicator concept licensed from the US DOE`s Brookhaven National Laboratory. The new system is the Advanced Flame Quality Indicator, or AFQI. As before, the AFQI monitors and reports the intensity of the burner flame relative to a calibration established when the burner is set up at AFQI installation. Repairs or adjustments are summoned by late-night outgoing telephone calls when limits are exceeded in either direction, indicating an impending contamination or other malfunction. A independently, a pressure transducer for monitoring oil tank level and filter condition, safety lockout alarms and a temperature monitor; all reporting automatically at instructed intervals via an on-board modem to a central station PC computer (CSC). Firmware on each AFQI unit and Insight-supplied software on the CSC automatically interact to maintain a customer database for an oil dealer, an OEM, or a regional service contractor. In addition to ensuring continuously clean and efficient operation, the AFQI offers the oil industry a new set of immediate payoffs, among which are reduced outages and emergency service calls, shorter service calls from cleaner operation, larger oil delivery drops, the opportunity to stretch service intervals to as along as three years in some cases, new selling features to keep and attract customers, and greatly enhanced customer contact, quality and reliability.

  20. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quality assurance and quality control. 26.167 Section 26... Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory shall have a quality assurance program that encompasses all...

  1. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quality assurance and quality control. 26.137 Section 26....137 Quality assurance and quality control. (a) Quality assurance program. Each licensee testing facility shall have a quality assurance program that encompasses all aspects of the testing...

  2. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project-longitudinal handling qualities study of a relaxed-stability airplane

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The results of a piloted simulation of longitudinal handling qualities of an airplane with relaxed static stability are described. This task was performed under the Integrated Application of Active Controls (IAAC) Technology Project within the NASA Energy Efficient Transport Program. A representative medium range transport airplane, the Boeing Model 757, was simulated. Evaluations were made of the unaugmented airplane and of the airplane with an Essential Pitch Augmented Stability (PAS) System and with a Primary PAS System at various center of gravity (cg) conditions. Level 2 pilot ratings were attained with cg locations aft to about 57% mean aerodynamic chord (MAC) or 6% aft of the neutral point for unaugmented landing approach. For Mach = 0.80, unaugmented cruise Level 2 ratings were attained to 47% MAC or 5% forward of the maneuver point. The augmented airplane model provided handling qualities close to or within the Level 1 boundary at all cg locations for both Essential and Primary PAS. Analyses of the test conditions when compared with existing handling qualities criteria based on classical unaugmented airplane characteristics agreed well with the pilot ratings. The unaugmented results are comparable to those reported by both the Douglas Aircraft Company and Lockheed California Company from simulation investigations of transport configurations with roughly similar dimensional and mass characteristics.

  3. Essential elements of quality control.

    PubMed

    Boylan, J C

    1983-11-01

    The components of quality control in the pharmaceutical industry are discussed as they apply to hospital pharmacy admixture services. The pharmaceutical industry complies with the FDA's Current Good Manufacturing Practices, which require manufacturers to have written procedures for ensuring sterility and nonpyrogenicity of injectable products. Because FDA specifies only what outcome measures must be assessed (rather than specific means of assessment), pharmaceutical companies have developed a multiplicity of quality-control systems. However, each system consists of a master formula (quantitative listing of all ingredients), master manufacturing instructions (the recipe for each product), master packaging instructions, and batch records. Documents used by quality control personnel include the specifications (identification, tests, and limits for products), test methods, and sampling procedures. Hospitals should have similar quality-control programs. These programs should systematically prevent or identify and correct deficiencies, measure overall quality, and provide information for managers. Hospital pharmacists whose departments do not have comprehensive programs should consult colleagues who have developed such procedures. Techniques used in industry should be applied when possible. To protect the integrity of manufacturers' drug products during compounding in hospitals, every hospital admixture service must have its own quality-control system. PMID:6650523

  4. Principles and Practices for Quality Assurance and Quality Control

    USGS Publications Warehouse

    Jones, Berwyn E.

    1999-01-01

    Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.

  5. Quality control in the year 2000

    PubMed Central

    Schade, Bernd

    1992-01-01

    ‘Just-in-time’ production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  6. Quality control in the year 2000.

    PubMed

    Schade, B

    1992-01-01

    'Just-in-time' production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  7. Analytical laboratory quality control charting

    SciTech Connect

    O'Bryan, Ervin F.

    2001-06-11

    In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of setting goals, process development, monitoring process indicators, fine tuning the process, and achieving results. These goals are to be focused and clearly measurable. In industry and life the setting of goals with clear process indicators is often difficult because of the variable end result and scarcity of measurements. Laboratories are fortunate in that they have a plethora of measurements with known or desired end results (controls) to monitor the process and give instantaneous feedback on quality. A key quality tool used by the laboratory to monitor and evaluate the lab processes is control charting. When properly utilized Quality Control (QC) Charts allow labs to be proactive in addressing problems rather than reactive. Several methods are available for control charting and some are listed in the references/information sources. The content for this paper is based on the control-charting program utilized at the Department of Energy's Fernald site. This control-charting program has specific areas of emphasis, simple charts, trend analyses, and effective follow-up.

  8. Quality control programme in mammography: second level quality controls.

    PubMed

    Nassivera, E; Nardin, L

    1997-06-01

    Mammography is the most reliable method by which to detect lesions in the breast. Since contrast between normal and pathological areas in the breast is extremely low, mammographic image quality should reach high standards without exceeding acceptable exposure levels for the breast. A quality control programme in mammography has been implemented. This programme is subdivided into two levels. The first consists of simple daily checks of image quality and film processing, while the second deals with more complex checks of mammographic unit, screen-film system, darkroom, illuminators, viewing conditions and reference dose determination. The values of all the parameters undergoing measurement are compared with the limiting values given by National and International Protocols. This paper describes the second level controls carried out every 6 months by the medical physicist. The parameters described are only those which have been studied and analysed in detail since the quality control programme in mammography was implemented. Such parameters (kilovoltage, focal spot dimension, half value layer, tube output, automatic exposure control system, screen-film characteristic curve and mean glandular dose) were measured during the period 1991-1995 and the results summarised. The values obtained prove the constant correct functioning of the equipment. PMID:9227255

  9. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Quality assurance and quality control. 26.167 Section 26.167 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory...

  10. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Quality assurance and quality control. 26.167 Section 26.167 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory...

  11. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Quality assurance and quality control. 26.167 Section 26.167 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory...

  12. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Quality assurance and quality control. 26.137 Section 26.137 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.137 Quality assurance and quality control. (a) Quality assurance program. Each licensee...

  13. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Quality assurance and quality control. 26.137 Section 26.137 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.137 Quality assurance and quality control. (a) Quality assurance program. Each licensee...

  14. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  15. Solidification process control for advanced superalloys

    NASA Technical Reports Server (NTRS)

    Gray, H. R.; Dreshfield, R. L.

    1982-01-01

    The importance of understanding and controlling the basic solidification process in high temperature alloy technology as applied to gas turbine engine production is discussed. Resultant tailoring of the superalloy macro- and microstructure offers significant potential for continued advances in superalloy use temperatures in turbine engines. Atomized superalloy powders, rapidly solidified superalloys, microstructural control, and advanced superalloys are discussed.

  16. Advanced control technology and its potential for future transport aircraft

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.

  17. High quality mask storage in an advanced Logic-Fab

    NASA Astrophysics Data System (ADS)

    Jähnert, Carmen; Fritsche, Silvio

    2012-02-01

    High efficient mask logistics as well as safe and high quality mask storage are essential requirements within an advanced lithography area of a modern logic waferfab. Fast operational availability of the required masks at the exposure tool with excellent mask condition requires a safe mask handling, safeguarding of high mask quality over the whole mask usage time without any quality degradation and an intelligent mask logistics. One big challenge is the prevention of haze on high advanced phase shift masks used in a high volume production line for some thousands of 248nm or 193nm exposures. In 2008 Infineon Dresden qualified a customer specific developed semi-bare mask storage system from DMSDynamic Micro Systems in combination with a high advanced mask handling and an interconnected complex logistic system. This high-capacity mask storage system DMS M1900.22 for more than 3000 masks with fully automated mask and box handling as well as full-blown XCDA purge has been developed and adapted to the Infineon Lithotoollandscape using Nikon and SMIF reticle cases. Advanced features for ESD safety and mask security, mask tracking via RFID and interactions with the exposure tools were developed and implemented. The stocker is remote controlled by the iCADA-RSM system, ordering of the requested mask directly from the affected exposure tool allows fast access. This paper discusses the advantages and challenges for this approach as well as the practical experience gained during the implementation of the new system which improves the fab performance with respect to mask quality, security and throughput. Especially the realization of an extremely low and stable humidity level in addition with a well controlled air flow at each mask surface, preventing masks from haze degradation and particle contamination, turns out to be a notable technical achievement. The longterm stability of haze critical masks has been improved significantly. Relevant environmental parameters like

  18. Quality control of EUVE databases

    NASA Technical Reports Server (NTRS)

    John, L. M.; Drake, J.

    1992-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer include: the EUVE Archive mailserver; the CEA ftp site; the EUVE Guest Observer Mailserver; and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public EUVE databases are working properly, and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this poster, we describe the Quality Assurance (QA) procedures we have developed from the approach of QA as a service organization, thus reflecting the overall EUVE philosophy of Quality Assurance integrated into normal operating procedures, rather than imposed as an external, post facto, control mechanism.

  19. Issues in advanced automation for manipulator control

    NASA Technical Reports Server (NTRS)

    Bejczy, A. K.

    1976-01-01

    This paper provides a brief description and analysis of the main issues in advanced autonomous control of manipulators as seen from a system point of view. The nature of manipulation is analyzed at some depth. A general multilevel structure is outlined for manipulator control organization which includes the human operator at the top level of the control structure. Different approaches to the development of advanced automation of mechanical arms are summarized. Recent work in the JPL teleoperator project is described, including control system, force/torque sensor, and control software development. Some results from control experiments are summarized.

  20. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 23 2014-07-01 2014-07-01 false Quality assurance and quality control. 136.7 Section 136.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) GUIDELINES ESTABLISHING TEST PROCEDURES FOR THE ANALYSIS OF POLLUTANTS § 136.7 Quality assurance and quality control. The...

  1. Recent advances in the application of computer-controlled optical finishing to produce very high-quality transmissive optical elements and windows

    NASA Astrophysics Data System (ADS)

    Askinazi, Joel; Estrin, Aleksandr; Green, Alan; Turner, Aaron N.

    2003-09-01

    Large aperture (20-inch diameter) sapphire optical windows have been identified as a key element of new and/or upgraded airborne electro-optical systems. These windows typically require a transmitted wave front error of much less than 0.1 waves rms @ 0.63 microns over 7 inch diameter sub-apertures. Large aperture (14-inch diameter by 4-inch thick) sapphire substrates have also been identified as a key optical element of the Laser Interferometer Gravitational Wave Observatory (LIGO). This project is under joint development by the California Institute of Technology (Caltech) and the Massachusetts Institute of Technology under cooperative agreement with the National Science foundation (NSF). These substrates are required to have a transmitted wave front error of 20 nm (0.032 waves) rms @ 0.63 microns over 6-inch sub-apertures with a desired error of 10 nm (0.016 waves) rms. Owing to the spatial variations in the optical index of refraction potentially anticipated within 20-inch diameter sapphire, thin (0.25 - 0.5-inch) window substrates, as well as within the 14-inch diameter by 4-inch thick substrates for the LIGO application, our experience tells us that the required transmitted wave front errors can not be achieved with standard optical finishing techniques as they can not readily compensate for errors introduced by inherent material characteristics. Computer controlled optical finishing has been identified as a key technology likely required to enable achievement of the required transmitted wave front errors. Goodrich has developed this technology and has previously applied it to finish high quality sapphire optical windows with a range of aperture sizes from 4-inch to 13-inch to achieve transmitted wavefront errors comparable to these new requirements. This paper addresses successful recent developments and accomplishments in the application of this optical finishing technology to sequentially larger aperture and thicker sapphire windows to achieve the

  2. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  3. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  4. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  5. Quality Control of Meteorological Observations

    NASA Technical Reports Server (NTRS)

    Collins, William; Dee, Dick; Rukhovets, Leonid

    1999-01-01

    For the first time, a problem of the meteorological observation quality control (QC) was formulated by L.S. Gandin at the Main Geophysical Observatory in the 70's. Later in 1988 L.S. Gandin began adapting his ideas in complex quality control (CQC) to the operational environment at the National Centers for Environmental Prediction. The CQC was first applied by L.S.Gandin and his colleagues to detection and correction of errors in rawinsonde heights and temperatures using a complex of hydrostatic residuals.Later, a full complex of residuals, vertical and horizontal optimal interpolations and baseline checks were added for the checking and correction of a wide range of meteorological variables. some other of Gandin's ideas were applied and substantially developed at other meteorological centers. A new statistical QC was recently implemented in the Goddard Data Assimilation System. The central component of any quality control is a buddy check which is a test of individual suspect observations against available nearby non-suspect observations. A novel feature of this test is that the error variances which are used for QC decision are re-estimated on-line. As a result, the allowed tolerances for suspect observations can depend on local atmospheric conditions. The system is then better able to accept extreme values observed in deep cyclones, jet streams and so on. The basic statements of this adaptive buddy check are described. Some results of the on-line QC including moisture QC are presented.

  6. Quality Assurance Protocol for AFCI Advanced Structural Materials Testing

    SciTech Connect

    Busby, Jeremy T

    2009-05-01

    application of NQA-1 requirements at the site. The current program is being revised to incorporate changes imposed through the recently revised AFCI Technical Integration Office QA requirements. Testing conducted under the AFCI QA program for the advanced structural materials effort shall incorporate the following quality assurance expectations: (1) personnel are adequately trained to perform assigned work; (2) activities are controlled to ensure consistency of results; (3) records necessary to substantiate how the work was performed are maintained (dedicated laboratory notebooks will be used); (4) the pedigree and traceability of the various tested materials are maintained throughout the described processes using consistent sample numbering and adequate record keeping; (5) equipment with the potential to affect the quality of the planned work is calibrated and maintained in accordance with applicable operating requirements. In addition, all reporting or related dissemination by ORNL personnel of the results of the work described in this subcontract shall be conducted in accordance with the requirements described or referenced in the ORNL Standards Based Management System subject area entitled Scientific and Technical Information. Reporting or publications at other institutions will be conducted in accordance with the requirements of that institution. Successful implementation of these protocols will provide a sound basis for future decisions and research. In addition, these steps will also help ensure that results can also be applied to licensing discussions at a future date.

  7. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  8. 7 CFR 981.42 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.42 Section 981.42 Agriculture... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this... establish, with the approval of the Secretary, such minimum quality and inspection requirements...

  9. Chapter 5: Quality assurance/quality control in stormwater sampling

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sampling the quality of stormwater presents unique challenges because stormwater flow is relatively short-lived with drastic variability. Furthermore, storm events often occur with little advance warning, outside conventional work hours, and under adverse weather conditions. Therefore, most stormwat...

  10. Advanced thermal control for spacecraft applications

    NASA Astrophysics Data System (ADS)

    Hardesty, Robert; Parker, Kelsey

    2015-09-01

    In optical systems just like any other space borne system, thermal control plays an important role. In fact, most advanced designs are plagued with volume constraints that further complicate the thermal control challenges for even the most experienced systems engineers. Peregrine will present advances in satellite thermal control based upon passive heat transfer technologies to dissipate large thermal loads. This will address the use of 700 W/m K and higher conducting products that are five times better than aluminum on a specific basis providing enabling thermal control while maintaining structural support.

  11. Annual Technol Conference Transactions - American Society for Quality Control, 34th: Quality in the New Decade, 1980

    SciTech Connect

    Not Available

    1980-05-01

    The conference transactions contain 129 papers dealing with such QC topics as: computer aided QC; metrology; human factors, risk, and product liability law; QC in food processing; statistical technique; quality costs principle; food, drug, and cosmetics; energy; automotive; metals; quality cost and startegic planning; quality motivation; textile and needle trades; environmental quality assurance; biomedical; service industry quality costs; application of quality circles; electronics; advanced reliability techniques; management; aerospace and defense planning and systems; small business quality control inspection; and reliability applications.

  12. Advanced Thermal HPT Clearance Control

    NASA Technical Reports Server (NTRS)

    WojciechVoytek, Sak

    2006-01-01

    OBJECTIVE: Develop a fast acting HPT Active Clearance Control System to improve engine efficiency and reduce emissions CHALLENGE: Reduction of HPT blade clearance throughout engine operation System complexity, reliability and cost must remain comparable or surpass today s engines Reduced clearance may increase possibility of rubs

  13. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts...

  14. A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol

    PubMed Central

    Houben, Carmen H M; Spruit, Martijn A; Wouters, Emiel F M; Janssen, Daisy J A

    2014-01-01

    Introduction Recent research shows that advance care planning (ACP) for patients with chronic obstructive pulmonary disease (COPD) is uncommon and poorly carried out. The aim of the present study was to explore whether and to what extent structured ACP by a trained nurse, in collaboration with the chest physician, can improve outcomes in Dutch patients with COPD and their family. Methods and analysis A multicentre cluster randomised controlled trial in patients with COPD who are recently discharged after an exacerbation has been designed. Patients will be recruited from three Dutch hospitals and will be assigned to an intervention or control group, depending on the randomisation of their chest physician. Patients will be assessed at baseline and after 6 and 12 months. The intervention group will receive a structured ACP session by a trained nurse. The primary outcomes are quality of communication about end-of-life care, symptoms of anxiety and depression, quality of end-of-life care and quality of dying. Secondary outcomes include concordance between patient's preferences for end-of-life care and received end-of-life care, and psychological distress in bereaved family members of deceased patients. Intervention and control groups will be compared using univariate analyses and clustered regression analysis. Ethics and dissemination Ethical approval was received from the Medical Ethical Committee of the Catharina Hospital Eindhoven, the Netherlands (NL42437.060.12). The current project provides recommendations for guidelines on palliative care in COPD and supports implementation of ACP in the regular clinical care. Clinical trial registration number NTR3940. PMID:24384905

  15. [Quality control in clinical trials].

    PubMed

    Fukushima, M

    1996-01-01

    Quality control (QC) in clinical trials means the procedures which insure protection of human subjects from research risk, reliability of the data, and thereby assures internal consistency. This has been developed since 1970s in the US, by establishing various regulations which are now called GCP. From the viewpoint of total QC, it should be emphasized that rigorous review of protocol by the Institutional Review Board and obtaining Informed Consent are prerequisites for insuring the quality of the given trial at high scientific level. When pursuing a clinical trial, first of all, facilities of the institutions and the ability of investigators must be of high quality. For this reason, at each institution previous data related to trials should be thoroughly reviewed and analyzed prior to developing a protocol. Educational courses in QC in clinical practice are invaluable. QC of diagnosis means, for example, central pathology review and standardization of diagnostic procedures and process. Secondly, at each institution, data managers collect the data and submit them to the central office at the indicated time. In order to evolve clinical trial, continuous education for data managers and expansion of their job are encouraged. Thirdly, at the statistical center independent from the research group office, subject-specific data managers, the biostatistical staff, must check submitted forms for completeness, consistency and accuracy. Finally, at the data analysis, quality evaluation of the research should also be carried out. Throughout the trial, monitoring and audit are particularly important to assure quality. The sponsor has the responsibility of monitoring the trial and make rigorous onsite visits, and the individual study group also have a monitoring program, while the FDA and the NCI audit by themselves. The purpose of audit is not only to assure data reliability but also to check out patient compliance to drug, education as to regulations and rules of clinical

  16. Learning to Control Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Subramanian, Devika

    2004-01-01

    Advanced life support systems have many interacting processes and limited resources. Controlling and optimizing advanced life support systems presents unique challenges. In particular, advanced life support systems are nonlinear coupled dynamical systems and it is difficult for humans to take all interactions into account to design an effective control strategy. In this project. we developed several reinforcement learning controllers that actively explore the space of possible control strategies, guided by rewards from a user specified long term objective function. We evaluated these controllers using a discrete event simulation of an advanced life support system. This simulation, called BioSim, designed by Nasa scientists David Kortenkamp and Scott Bell has multiple, interacting life support modules including crew, food production, air revitalization, water recovery, solid waste incineration and power. They are implemented in a consumer/producer relationship in which certain modules produce resources that are consumed by other modules. Stores hold resources between modules. Control of this simulation is via adjusting flows of resources between modules and into/out of stores. We developed adaptive algorithms that control the flow of resources in BioSim. Our learning algorithms discovered several ingenious strategies for maximizing mission length by controlling the air and water recycling systems as well as crop planting schedules. By exploiting non-linearities in the overall system dynamics, the learned controllers easily out- performed controllers written by human experts. In sum, we accomplished three goals. We (1) developed foundations for learning models of coupled dynamical systems by active exploration of the state space, (2) developed and tested algorithms that learn to efficiently control air and water recycling processes as well as crop scheduling in Biosim, and (3) developed an understanding of the role machine learning in designing control systems for

  17. Research of data quality control based on quality grading

    NASA Astrophysics Data System (ADS)

    Liu, Shuang Hong; Yu, Jian Guo; Yu, Yong Ling

    2012-01-01

    To solve the problem of data quality in data warehouse, the process of data stream in data warehouse and the factors influencing data quality were analyzed; a method for controlling data quality based on quality grading was proposed and the frame of data quality grading system was established. In each process of ETL, the data quality grading system would execute script to calculate values, such as total, component and standard measures in accordance with the definition of Unit Measure, so as to get representation indexes; and then the quality report would be generated according to the indexes and the quality would be graded. The method is applicable to various data warehouse systems.

  18. Research of data quality control based on quality grading

    NASA Astrophysics Data System (ADS)

    Liu, Shuang Hong; Yu, Jian Guo; Yu, Yong Ling

    2011-12-01

    To solve the problem of data quality in data warehouse, the process of data stream in data warehouse and the factors influencing data quality were analyzed; a method for controlling data quality based on quality grading was proposed and the frame of data quality grading system was established. In each process of ETL, the data quality grading system would execute script to calculate values, such as total, component and standard measures in accordance with the definition of Unit Measure, so as to get representation indexes; and then the quality report would be generated according to the indexes and the quality would be graded. The method is applicable to various data warehouse systems.

  19. JPL Advanced Thermal Control Technology Roadmap - 2012

    NASA Technical Reports Server (NTRS)

    Birur, Gaj; Rodriguez, Jose I.

    2012-01-01

    NASA's new emphasis on human exploration program for missions beyond LEO requires development of innovative and revolutionary technologies. Thermal control requirements of future NASA science instruments and missions are very challenging and require advanced thermal control technologies. Limited resources requires organizations to cooperate and collaborate; government, industry, universities all need to work together for the successful development of these technologies.

  20. Experimental development of power reactor advanced controllers

    SciTech Connect

    Edwards, R.M.; Weng, C.K.; Lindsay, R.W.

    1992-06-01

    A systematic approach for developing and verifying advanced controllers with potential application to commercial nuclear power plants is suggested. The central idea is to experimentally demonstrate an advanced control concept first on an ultra safe research reactor followed by demonstration on a passively safe experimental power reactor and then finally adopt the technique for improving safety, performance, reliability and operability at commercial facilities. Prior to completing an experimental sequence, the benefits and utility of candidate advanced controllers should be established through theoretical development and simulation testing. The applicability of a robust optimal observer-based state feedback controller design process for improving reactor temperature response for a TRIGA research reactor, Liquid Metal-cooled Reactor (LMR), and a commercial Pressurized Water Reactor (PWR) is presented to illustrate the potential of the proposed experimental development concept.

  1. Experimental development of power reactor advanced controllers

    SciTech Connect

    Edwards, R.M. . Dept. of Nuclear Engineering); Weng, C.K. . Dept. of Mechanical Engineering); Lindsay, R.W. )

    1992-01-01

    A systematic approach for developing and verifying advanced controllers with potential application to commercial nuclear power plants is suggested. The central idea is to experimentally demonstrate an advanced control concept first on an ultra safe research reactor followed by demonstration on a passively safe experimental power reactor and then finally adopt the technique for improving safety, performance, reliability and operability at commercial facilities. Prior to completing an experimental sequence, the benefits and utility of candidate advanced controllers should be established through theoretical development and simulation testing. The applicability of a robust optimal observer-based state feedback controller design process for improving reactor temperature response for a TRIGA research reactor, Liquid Metal-cooled Reactor (LMR), and a commercial Pressurized Water Reactor (PWR) is presented to illustrate the potential of the proposed experimental development concept.

  2. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....359 Quality control. Quality control measures shall insure that emission testing equipment is... 40 Protection of Environment 2 2013-07-01 2013-07-01 false Quality control. 51.359 Section 51.359... of tests) which fall into the testing categories identified. Alternatives or exceptions to...

  3. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....359 Quality control. Quality control measures shall insure that emission testing equipment is... 40 Protection of Environment 2 2014-07-01 2014-07-01 false Quality control. 51.359 Section 51.359... of tests) which fall into the testing categories identified. Alternatives or exceptions to...

  4. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....359 Quality control. Quality control measures shall insure that emission testing equipment is... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Quality control. 51.359 Section 51.359... of tests) which fall into the testing categories identified. Alternatives or exceptions to...

  5. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  6. 14 CFR 21.139 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  7. 7 CFR 981.42 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in...

  8. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  9. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product...

  10. 14 CFR 21.139 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  11. Operational efficiency subpanel advanced mission control

    NASA Technical Reports Server (NTRS)

    Friedland, Peter

    1990-01-01

    Herein, the term mission control will be taken quite broadly to include both ground and space based operations as well as the information infrastructure necessary to support such operations. Three major technology areas related to advanced mission control are examined: (1) Intelligent Assistance for Ground-Based Mission Controllers and Space-Based Crews; (2) Autonomous Onboard Monitoring, Control and Fault Detection Isolation and Reconfiguration; and (3) Dynamic Corporate Memory Acquired, Maintained, and Utilized During the Entire Vehicle Life Cycle. The current state of the art space operations are surveyed both within NASA and externally for each of the three technology areas and major objectives are discussed from a user point of view for technology development. Ongoing NASA and other governmental programs are described. An analysis of major research issues and current holes in the program are provided. Several recommendations are presented for enhancing the technology development and insertion process to create advanced mission control environments.

  12. Quality assurance and quality control in monitoring programs

    USGS Publications Warehouse

    Shampine, W.J.

    1993-01-01

    There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these characteristics are addressed effectively by quality assurance and quality control. One of the most important aspects of quality assurance in a monitoring program is the development of a quality assurance plan, which should identify clearly the quality of the data needed and describe in detail the planned actions to provide confidence that the program will meet its stated objectives. Quality control data, which allow for the quality and suitability of the environmental data to be evaluated and ascertained, should be collected and utilized as an integral part of the QA effort associated with a monitoring program.

  13. Business quality control in issuing life insurance.

    PubMed

    Roberts, N K

    1999-01-01

    Fraud investigation and fraud control are entirely different processes. Similarly the auditing of a life insurance company and the issuing of life insurance policies and business quality control are not the same. Business quality control and fraud control have much in common. In this article, these similarities are explored and a case is made that companies issuing life insurance policies should consider the business quality control approach rather than the more traditional investigatory methods. PMID:10539385

  14. Quality Control of EUVE Databases

    NASA Astrophysics Data System (ADS)

    John, Linda M.

    1993-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer (EUVE) include: the EUVE Archive Mailserver, the Center for EUV Astrophysics ftp site, the EUVE Guest Observer Mailserver, and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public databases are working properly and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this paper, we describe the quality assurance (QA) procedures we have developed from approaching QA as a service organization; this approach reflects the overall EUVE philosophy of QA integrated into normal operating procedures, rather than imposed as an external, post-facto, control mechanism.

  15. Advanced control architecture for autonomous vehicles

    NASA Astrophysics Data System (ADS)

    Maurer, Markus; Dickmanns, Ernst D.

    1997-06-01

    An advanced control architecture for autonomous vehicles is presented. The hierarchical architecture consists of four levels: a vehicle level, a control level, a rule-based level and a knowledge-based level. A special focus is on forms of internal representation, which have to be chosen adequately for each level. The control scheme is applied to VaMP, a Mercedes passenger car which autonomously performs missions on German freeways. VaMP perceives the environment with its sense of vision and conventional sensors. It controls its actuators for locomotion and attention focusing. Modules for perception, cognition and action are discussed.

  16. Advanced instrumentation concepts for environmental control subsystems

    NASA Technical Reports Server (NTRS)

    Yang, P. Y.; Schubert, F. H.; Gyorki, J. R.; Wynveen, R. A.

    1978-01-01

    Design, evaluation and demonstration of advanced instrumentation concepts for improving performance of manned spacecraft environmental control and life support systems were successfully completed. Concepts to aid maintenance following fault detection and isolation were defined. A computer-guided fault correction instruction program was developed and demonstrated in a packaged unit which also contains the operator/system interface.

  17. Yield advances in peanut - weed control effects

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Improvements in weed management are a contributing factor to advancements in peanut yield. Widespread use of vacuum planters and increased acceptance of narrow row patterns enhance weed control by lessening bareground caused by skips and promoting quick canopy closure. Cultivation was traditionall...

  18. Microprocessor controlled advanced battery management systems

    NASA Technical Reports Server (NTRS)

    Payne, W. T.

    1978-01-01

    The advanced battery management system described uses the capabilities of an on-board microprocessor to: (1) monitor the state of the battery on a cell by cell basis; (2) compute the state of charge of each cell; (3) protect each cell from reversal; (4) prevent overcharge on each individual cell; and (5) control dual rate reconditioning to zero volts per cell.

  19. Advanced technologies for Mission Control Centers

    NASA Technical Reports Server (NTRS)

    Dalton, John T.; Hughes, Peter M.

    1991-01-01

    Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

  20. MERCURY CONTROL WITH ADVANCED HYBRID PARTICULATE COLLECTOR

    SciTech Connect

    Ye Zhuang; Stanley J. Miller

    2005-05-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addressed Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team included the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Power Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and has been marketed as the Advanced Hybrid{trademark} filter by Gore. The Advanced Hybrid{trademark} filter combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The Advanced Hybrid{trademark} filter provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The Advanced Hybrid{trademark} filter also appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas--solid contactor. The objective of the project was to demonstrate 90% total mercury control in the Advanced Hybrid{trademark} filter at a lower cost than current mercury control estimates. The approach included bench-scale batch tests, larger-scale pilot testing with real flue gas on a coal-fired combustion system, and field demonstration at the 2.5-MW (9000-acfm) scale at a utility power plant to prove scale-up and demonstrate longer-term mercury control

  1. Advanced Active Thermal Control Systems Architecture Study

    NASA Technical Reports Server (NTRS)

    Hanford, Anthony J.; Ewert, Michael K.

    1996-01-01

    The Johnson Space Center (JSC) initiated a dynamic study to determine possible improvements available through advanced technologies (not used on previous or current human vehicles), identify promising development initiatives for advanced active thermal control systems (ATCS's), and help prioritize funding and personnel distribution among many research projects by providing a common basis to compare several diverse technologies. Some technologies included were two-phase thermal control systems, light-weight radiators, phase-change thermal storage, rotary fluid coupler, and heat pumps. JSC designed the study to estimate potential benefits from these various proposed and under-development thermal control technologies for five possible human missions early in the next century. The study compared all the technologies to a baseline mission using mass as a basis. Each baseline mission assumed an internal thermal control system; an external thermal control system; and aluminum, flow-through radiators. Solar vapor compression heat pumps and light-weight radiators showed the greatest promise as general advanced thermal technologies which can be applied across a range of missions. This initial study identified several other promising ATCS technologies which offer mass savings and other savings compared to traditional thermal control systems. Because the study format compares various architectures with a commonly defined baseline, it is versatile and expandable, and is expected to be updated as needed.

  2. Coal surface control for advanced fine coal flotation

    SciTech Connect

    Fuerstenau, D.W.; Hanson, J.S.; Diao, J.; Harris, G.H.; De, A.; Sotillo, F. ); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. ); Hu, W.; Zou, Y.; Chen, W. ); Choudhry, V.; Shea, S.; Ghosh, A.; Sehgal, R. )

    1992-03-01

    The initial goal of the research project was to develop methods of coal surface control in advanced froth flotation to achieve 90% pyritic sulfur rejection, while operating at Btu recoveries above 90% based on run-of-mine quality coal. Moreover, the technology is to concomitantly reduce the ash content significantly (to six percent or less) to provide a high-quality fuel to the boiler (ash removal also increases Btu content, which in turn decreases a coal's emission potential in terms of lbs SO{sub 2}/million Btu). (VC)

  3. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 24 2012-07-01 2012-07-01 false Quality assurance and quality control. 136.7 Section 136.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... referred to as a spiked blank, or laboratory control sample (LCS); (v) Matrix spike (MS) and matrix...

  4. QUALITY CONTROL - VARIABILITY IN PROTOCOLS

    EPA Science Inventory

    The EPA Risk Reduction Engineering Laboratory’s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

  5. Computers and quality control in nuclear medicine.

    PubMed

    Brookeman, V A

    1978-04-01

    The general topic of computers and nuclear medicine quality control may be approached from two main areas; controlling the quality of computerized studies, and computer applications in general nuclear medicine quality control. Overlap occurs when quality control of computer studies is performed by the computer itself. The uses of computers in record-keeping and in quality control of imaging instrumentation and in vitro studies, including radioimmunoassay, are discussed in this review. Aspects of quality control for computerized clinical cardiovascular, cerebral, and renal studies and emission computed tomography are reviewed, including consideration of difficulties and inaccuracies involved in the studies. Any automatic computer analysis program should incorporate adequate checks and error detection protocols and should illustrate results for verification. Current routine quality control procedures using the computer unfortunately are few. Quality control criteria are needed for camera/computer systems in high count rate clinical applications, and increasing emphasis should be aimed at quality control of those computerized dynamic and function studies in current clinical use. The computer has a valuable potential for nuclear medicine quality control. In vitro and computerized in vivo studies can be analyzed by readily available statistical programs, and variances can be monitored continuously. Computers can calibrate and monitor instrument performance regularly, and can handle managerial and clerical duties such as bookkeeping. PMID:684439

  6. Architectures & requirements for advanced weapon controllers.

    SciTech Connect

    McMurtrey, Brian J.; Klarer, Paul Richard; Bryan, Jon R.

    2004-02-01

    This report describes work done in FY2003 under Advanced and Exploratory Studies funding for Advanced Weapons Controllers. The contemporary requirements and envisioned missions for nuclear weapons are changing from the class of missions originally envisioned during development of the current stockpile. Technology available today in electronics, computing, and software provides capabilities not practical or even possible 20 years ago. This exploratory work looks at how Weapon Electrical Systems can be improved to accommodate new missions and new technologies while maintaining or improving existing standards in nuclear safety and reliability.

  7. Introduction to Advanced Engine Control Concepts

    NASA Technical Reports Server (NTRS)

    Sanjay, Garg

    2007-01-01

    With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Branch at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced controls and health management technologies that will help meet these challenges through the concept of Intelligent Propulsion Systems. The key enabling technologies for an Intelligent Propulsion System are the increased efficiencies of components through active control, advanced diagnostics and prognostics integrated with intelligent engine control to enhance operational reliability and component life, and distributed control with smart sensors and actuators in an adaptive fault tolerant architecture. This presentation describes the current activities of the Controls and Dynamics Branch in the areas of active component control and propulsion system intelligent control, and presents some recent analytical and experimental results in these areas.

  8. Human factors challenges for advanced process control

    SciTech Connect

    Stubler, W.F.; O`Hara, J..M.

    1996-08-01

    New human-system interface technologies provide opportunities for improving operator and plant performance. However, if these technologies are not properly implemented, they may introduce new challenges to performance and safety. This paper reports the results from a survey of human factors considerations that arise in the implementation of advanced human-system interface technologies in process control and other complex systems. General trends were identified for several areas based on a review of technical literature and a combination of interviews and site visits with process control organizations. Human factors considerations are discussed for two of these areas, automation and controls.

  9. Exposure tool control for advanced semiconductor lithography

    NASA Astrophysics Data System (ADS)

    Matsuyama, Tomoyuki

    2015-08-01

    This is a review paper to show how we control exposure tool parameters in order to satisfy patterning performance and productivity requirements for advanced semiconductor lithography. In this paper, we will discuss how we control illumination source shape to satisfy required imaging performance, heat-induced lens aberration during exposure to minimize the aberration impact on imaging, dose and focus control to realize uniform patterning performance across the wafer and patterning position of circuit patterns on different layers. The contents are mainly about current Nikon immersion exposure tools.

  10. Advanced helicopter cockpit and control configurations for helicopter combat missions

    NASA Technical Reports Server (NTRS)

    Haworth, Loran A.; Atencio, Adolph, Jr.; Bivens, Courtland; Shively, Robert; Delgado, Daniel

    1987-01-01

    Two piloted simulations were conducted by the U.S. Army Aeroflightdynamics Directorate to evaluate workload and helicopter-handling qualities requirements for single pilot operation in a combat Nap-of-the-Earth environment. The single-pilot advanced cockpit engineering simulation (SPACES) investigations were performed on the NASA Ames Vertical Motion Simulator, using the Advanced Digital Optical Control System control laws and an advanced concepts glass cockpit. The first simulation (SPACES I) compared single pilot to dual crewmember operation for the same flight tasks to determine differences between dual and single ratings, and to discover which control laws enabled adequate single-pilot helicopter operation. The SPACES II simulation concentrated on single-pilot operations and use of control laws thought to be viable candidates for single pilot operations workload. Measures detected significant differences between single-pilot task segments. Control system configurations were task dependent, demonstrating a need for inflight reconfigurable control system to match the optimal control system with the required task.

  11. Summary of beam quality diagnostics and control working group

    SciTech Connect

    Lewellen, John; Piot, Philippe; /Northern Illinois U. /Fermilab

    2006-09-01

    The working group on beam quality, diagnostics, and control at the 12th Advanced Accelerator Concepts Workshop held a series of meetings during the Workshop. The generation of bright charged-particle beams (in particular electron and positron beams), along with state-of-the-art beam diagnostics and synchronization were discussed.

  12. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Quality control. 74.6 Section 74.6 Mineral... control. The applicant shall describe the way in which each lot of components will be sampled and tested... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA...

  13. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quality control. 74.6 Section 74.6 Mineral... control. The applicant shall describe the way in which each lot of components will be sampled and tested... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA...

  14. INTEGRATED PLASMA CONTROL FOR ADVANCED TOKAMAKS

    SciTech Connect

    HUMPHREYS,D.A; FERRON,J.R; JOHNSON,R.D; LEUER,J.A; PENAFLOR,B.G; WALKER,M.L; WELANDER,A.S; KHAYRUTDINOV,R.R; DOKOUKA,V; EDGELL,D.H; FRANSSON,C.M

    2003-10-01

    OAK-B135 Advanced tokamaks (AT) are distinguished from conventional tokamaks by their high degree of shaping, achievement of profiles optimized for high confinement and stability characteristics, and active stabilization of MHD instabilities to attain high values of normalized beta and confinement. These high performance fusion devices thus require accurate regulation of the plasma boundary, internal profiles, pumping, fueling, and heating, as well as simultaneous and well-coordinated MHD control action to stabilize such instabilities as tearing modes and resistive wall modes. Satisfying the simultaneous demands on control accuracy, reliability, and performance for all of these subsystems requires a high degree of integration in both design and operation of the plasma control system in an advanced tokamak. The present work describes the approach, benefits, and progress made in integrated plasma control with application examples drawn from the DIII-D tokamak. The approach includes construction of plasma and system response models, validation of models against operating experiments, design of integrated controllers which operate in concert with one another as well as with supervisory modules, simulation of control action against off-line and actual machine control platforms, and iteration of the design-test loop to optimize performance.

  15. Advanced control strategies for fluidized bed dryers

    SciTech Connect

    Siettos, C.I.; Kiranoudis, C.T.; Bafas, G.V.

    1999-11-01

    Generating the best possible control strategy comprises a necessity for industrial processes, by virtue of product quality, cost reduction and design simplicity. Three different control approaches, namely an Input-Output linearizing, a fuzzy logic and a PID controller, are evaluated for the control of a fluidized bed dryer, a typical non-linear drying process of wide applicability. Based on several closed loop characteristics such as settling times, maximum overshoots and dynamic performance criteria such as IAE, ISE and ITAE, it is shown that the Input-Output linearizing and the fuzzy logic controller exhibit a better performance compared to the PID controller tuned optimally with respect to IAE, for a wide range of disturbances; yet, the relevant advantage of the fuzzy logic over the conventional nonlinear controller issues upon its design simplicity. Typical load rejection and set-point tracking examples are given to illustrate the effectiveness of the proposed approach.

  16. Operational Quality Control of SAR Data under the IDEAS Contract

    NASA Astrophysics Data System (ADS)

    Griffiths, Emma; Haria, Kajal; Meadowws, Peter; Miranda, Nuno

    2010-12-01

    Operational Quality Control (QC) of ERS-1/2 Synthetic Aperture Radar (SAR), Envisat's Advanced Synthetic Aperture Radar (ASAR) and the Phased-Array L-band SAR (PALSAR) on board JAXA's Advanced Land Observing Satellite (ALOS) is currently carried out under the Image Data quality Evaluation and Analysis Service (IDEAS). This paper introduces the concept of IDEAS as it applies to SAR QC including the daily and long-term analysis and shows the interaces to related services, including ESA's user-facing Earth Observation (EO) Help Desk

  17. An advanced control system for a next generation transport aircraft

    NASA Technical Reports Server (NTRS)

    Rising, J. J.; Davis, W. J; Grantham, W. D.

    1983-01-01

    The use of modern control theory to develop a high-authority stability and control system for the next generation transport aircraft is described with examples taken from work performed on an advanced pitch active control system (PACS). The PACS was configured to have short-period and phugoid modes frequency and damping characteristics within the shaded S-plane areas, column force gradients with set bounds and with constant slope, and a blended normal-acceleration/pitch rate time history response to a step command. Details of the control law, feedback loop, and modal control syntheses are explored, as are compensation for the feedback gain, the deletion of the velocity signal, and the feed-forward compensation. Scheduling of the primary and secondary gains are discussed, together with control law mechanization, flying qualities analyses, and application on the L-1011 aircraft.

  18. Advanced avionics concepts: Autonomous spacecraft control

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A large increase in space operations activities is expected because of Space Station Freedom (SSF) and long range Lunar base missions and Mars exploration. Space operations will also increase as a result of space commercialization (especially the increase in satellite networks). It is anticipated that the level of satellite servicing operations will grow tenfold from the current level within the next 20 years. This growth can be sustained only if the cost effectiveness of space operations is improved. Cost effectiveness is operational efficiency with proper effectiveness. A concept is presented of advanced avionics, autonomous spacecraft control, that will enable the desired growth, as well as maintain the cost effectiveness (operational efficiency) in satellite servicing operations. The concept of advanced avionics that allows autonomous spacecraft control is described along with a brief description of each component. Some of the benefits of autonomous operations are also described. A technology utilization breakdown is provided in terms of applications.

  19. Quality Control in Small Groups

    NASA Astrophysics Data System (ADS)

    Lemmens, L. F.

    2008-11-01

    The smallness of some groups in a set up to control the quality of a service using questionnaires limits the size of the samples, this limitation has several consequences. Indeed the common approach used for relatively large groups, based on the central limit theorem and the law of large numbers, cannot be used anymore to construct estimators for the parameters of the model. Using an inverse probability will lift these restrictions. A questionnaire is a collection of items. In an item the respondent indicates on a Likert scale his or her agreement with a statement. Dimensions are a set of items dealing with one aspect of the service. In a questionnaire several dimensions are addressed but usually the items are presented in a random sequence. The model for an item is hierarchical with following components: a multivariate hypergeometric model takes the sampling in a finite population into account, the multinomial serves as a prior for the sampling and the Dirichlet-distribution serves as a prior for the multinomials. The composition of dimensions allows to use the posterior for one of the items as a prior for another item of that dimension and so on. After analysis of several questionnaires using this model, the reliability of the responses from some respondents turned out to be a key-problem, in the sense the responses can be classified into at least two classes and a decision rule had to be developed to neglect some of them. The influence of rejecting some answers, on the confidence for the most plausible statement can be estimated. This leads often to the result that there is only minimal evidence for the most probable statement.

  20. The Advanced Noise Control Fan Baseline Measurements

    NASA Technical Reports Server (NTRS)

    McAllister, Joseph; Loew, Raymond A.; Lauer, Joel T.; Stuliff, Daniel L.

    2009-01-01

    The NASA Glenn Research Center s (NASA Glenn) Advanced Noise Control Fan (ANCF) was developed in the early 1990s to provide a convenient test bed to measure and understand fan-generated acoustics, duct propagation, and radiation to the farfield. As part of a complete upgrade, current baseline and acoustic measurements were documented. Extensive in-duct, farfield acoustic, and flow field measurements are reported. This is a follow-on paper to documenting the operating description of the ANCF.

  1. QUEST FOR AN ADVANCED REGIONAL AIR QUALITY MODEL

    EPA Science Inventory

    Organizations interested in advancing the science and technology of regional air quality modeling on the "grand challenge" scale have joined to form CAMRAQ. hey plan to leverage their research finds by collaborating on the development and evaluation of CMSs so ambitious in scope ...

  2. Colorado Air Quality Control Regulations and Ambient Air Quality Standards.

    ERIC Educational Resources Information Center

    Colorado State Dept. of Health, Denver. Div. of Air Pollution Control.

    Regulations and standards relative to air quality control in Colorado are defined in this publication. Presented first are definitions of terms, a statement of intent, and general provisions applicable to all emission control regulations adopted by the Colorado Air Pollution Control Commission. Following this, three regulations are enumerated: (1)…

  3. Annual technical conference transactions. American Society for Quality Control, 34th: quality in the new decade, 1980

    SciTech Connect

    Not Available

    1981-01-01

    The conference transactions contain 129 papers dealing with such QC topics as: computer aided QC; metrology; human factors, risk, and product liability law; QC in food processing; statistical techniques; quality costs principle; food, drug, and cosmetics; energy; automotive; metals; quality cost and strategic planning; quality motivation; textile and needle trades; environmental quality assurance; biomedical; service industry quality costs; application of quality circles; electronics; advanced reliability techniques; inspection application; chemical quality management; aerospace and defense planning and systems; small business quality control inspection; and reliability applications.

  4. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control. 74.6 Section 74.6 Mineral... DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6 Quality... to maintain its quality prior to assembly of each sampler unit. In order to assure that the...

  5. Handling qualities requirements for control configured vehicles

    NASA Technical Reports Server (NTRS)

    Woodcock, R. J.; George, F. L.

    1976-01-01

    The potential effects of fly by wire and control configured vehicle concepts on flying qualities are considered. Failure mode probabilities and consequences, controllability, and dynamics of highly augmented aircraft are among the factors discussed in terms of design criteria.

  6. Quality control education in the community college

    NASA Technical Reports Server (NTRS)

    Greene, J. Griffen; Wilson, Steve

    1966-01-01

    This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

  7. Control definition study for advanced vehicles

    NASA Technical Reports Server (NTRS)

    Lapins, M.; Martorella, R. P.; Klein, R. W.; Meyer, R. C.; Sturm, M. J.

    1983-01-01

    The low speed, high angle of attack flight mechanics of an advanced, canard-configured, supersonic tactical aircraft designed with moderate longitudinal relaxed static stability (Static Margin, SM = 16% C sub W at M = 0.4) was investigated. Control laws were developed for the longitudinal axis (""G'' or maneuver and angle of attack command systems) and for the lateral/directional axes. The performance of these control laws was examined in engineering simulation. A canard deflection/rate requirement study was performed as part of the ""G'' command law evaluation at low angles of attack. Simulated coupled maneuvers revealed the need for command limiters in all three aircraft axes to prevent departure from controlled flight. When modified with command/maneuver limiters, the control laws were shown to be adequate to prevent aircraft departure during aggressive air combat maneuvering.

  8. Professional Development for Water Quality Control Personnel.

    ERIC Educational Resources Information Center

    Shepard, Clinton Lewis

    This study investigated the availability of professional development opportunities for water quality control personnel in the midwest. The major objective of the study was to establish a listing of educational opportunities for the professional development of water quality control personnel and to compare these with the opportunities technicians…

  9. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN CERP Implementation... quality control plan, in accordance with applicable Corps of Engineers regulations, for each product that will be produced by a Project Delivery Team. The quality control plan shall be included in the...

  10. Quality Control Technician Curriculum. An Elusive Butterfly.

    ERIC Educational Resources Information Center

    Holler, Michael

    Defining and developing a quality control technician curriculum for an associate degree program is a difficult and puzzling job. There are as many definitions of quality control and curriculum ideas as there are educators asked. However, one could start by dividing the field into its major areas--heavy manufacturing, maintenance, research, and…

  11. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control. 74.6 Section 74.6 Mineral... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA and... DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  12. Advanced control design for hybrid turboelectric vehicle

    NASA Astrophysics Data System (ADS)

    Abban, Joseph; Norvell, Johnesta; Momoh, James A.

    1995-08-01

    The new environment standards are a challenge and opportunity for industry and government who manufacture and operate urban mass transient vehicles. A research investigation to provide control scheme for efficient power management of the vehicle is in progress. Different design requirements using functional analysis and trade studies of alternate power sources and controls have been performed. The design issues include portability, weight and emission/fuel efficiency of induction motor, permanent magnet and battery. A strategic design scheme to manage power requirements using advanced control systems is presented. It exploits fuzzy logic, technology and rule based decision support scheme. The benefits of our study will enhance the economic and technical feasibility of technological needs to provide low emission/fuel efficient urban mass transit bus. The design team includes undergraduate researchers in our department. Sample results using NASA HTEV simulation tool are presented.

  13. Quality-control analytical methods: continuous quality improvement.

    PubMed

    Venti, Eden M

    2006-01-01

    It is vital that all compounding pharmacies have a continuous quality improvement program in place by way of standard operating procedures to assure that patients receive high-quality preparations. The program should take into consideration any federal and state regulatory requirements, as well as professional association expectations. Quality control measurements and regular review of those measurements are the foundations of a good quality plan. All pharmacy personnel should be aware of the importance of reporting potential internal quality concerns or problems and should be encouraged to do so without fear of repercussions. Ideally, an error-free compounding pracitice would be the goal. Since this is not practical, quality issues should not be viewed as problems, but as opportunities to improve compounding practices by correcting, before they become pervasive, the processes used in the preparation of prescriptions. PMID:23974418

  14. JPL Advanced Thermal Control Technology Roadmap - 2008

    NASA Technical Reports Server (NTRS)

    Birur, Gaj

    2008-01-01

    This slide presentation reviews the status of thermal control technology at JPL and NASA.It shows the active spacecraft that are in vairous positions in the solar syatem, and beyond the solar system and the future missions that are under development. It then describes the challenges that the past missions posed with the thermal control systems. The various solutions that were implemented duirng the decades prior to 1990 are outlined. A review of hte thermal challenges of the future misions is also included. The exploration plan for Mars is then reviewed. The thermal challenges of the Mars Rovers are then outlined. Also the challenges of systems that would be able to be used in to explore Venus, and Titan are described. The future space telescope missions will also need thermal control technological advances. Included is a review of the thermal requirements for manned missions to the Moon. Both Active and passive technologies that have been used and will be used are reviewed. Those that are described are Mechanically Pumped Fluid Loops (MPFL), Loop Heat Pipes, an M3 Passive Cooler, Heat Siwtch for Space and Mars surface applications, phase change material (PCM) technology, a Gas Gap Actuateor using ZrNiH(x), the Planck Sorption Cooler (PCS), vapor compression -- Hybrid two phase loops, advanced pumps for two phase cooling loops, and heat pumps that are lightweight and energy efficient.

  15. Water Quality Control, Curriculum Guide.

    ERIC Educational Resources Information Center

    Washington City Board of Education, NC.

    Activities which study how water is used, contaminated, and treated or purified are presented in this curriculum guide, culminating in the investigation of a local water quality problem. Designed as a 12 week mini-course for students in grades eight and nine, the guide first presents a review of the content, objectives, major concepts, and sources…

  16. Advanced nuclear plant control room complex

    DOEpatents

    Scarola, Kenneth; Jamison, David S.; Manazir, Richard M.; Rescorl, Robert L.; Harmon, Daryl L.

    1993-01-01

    An advanced control room complex for a nuclear power plant, including a discrete indicator and alarm system (72) which is nuclear qualified for rapid response to changes in plant parameters and a component control system (64) which together provide a discrete monitoring and control capability at a panel (14-22, 26, 28) in the control room (10). A separate data processing system (70), which need not be nuclear qualified, provides integrated and overview information to the control room and to each panel, through CRTs (84) and a large, overhead integrated process status overview board (24). The discrete indicator and alarm system (72) and the data processing system (70) receive inputs from common plant sensors and validate the sensor outputs to arrive at a representative value of the parameter for use by the operator during both normal and accident conditions, thereby avoiding the need for him to assimilate data from each sensor individually. The integrated process status board (24) is at the apex of an information hierarchy that extends through four levels and provides access at each panel to the full display hierarchy. The control room panels are preferably of a modular construction, permitting the definition of inputs and outputs, the man machine interface, and the plant specific algorithms, to proceed in parallel with the fabrication of the panels, the installation of the equipment and the generic testing thereof.

  17. Control by quality: proposition of a typology.

    PubMed

    Pujo, P; Pillet, M

    The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control

  18. [Comparing quality measurements Part 2: control charts].

    PubMed

    Kottner, Jan; Hauss, Armin

    2013-04-01

    Comparative quality measurements and evaluations in nursing play significant roles. Quality measures are affected by systematic and random error. Statistical Process Control (SPC) offers a method to take random variation adequately into account. In this article, control charts are introduced. Those are graphical displays to show quality measures over time. Attribute variables can be displayed by p-, u- and c-control charts. Special cause variations within the processes can be detected by rules. If signs for special cause variations are absent, the process in considered being in statistical control showing common cause variation. A deviation of one data point greater than three standard deviations from the arithmetic mean is considered the strongest signal for non random variation within the process. Within quality improvement contexts control charts outperform traditional comparisons of means and spreads. PMID:23535476

  19. Advanced Wavefront Sensing and Control Testbed (AWCT)

    NASA Technical Reports Server (NTRS)

    Shi, Fang; Basinger, Scott A.; Diaz, Rosemary T.; Gappinger, Robert O.; Tang, Hong; Lam, Raymond K.; Sidick, Erkin; Hein, Randall C.; Rud, Mayer; Troy, Mitchell

    2010-01-01

    The Advanced Wavefront Sensing and Control Testbed (AWCT) is built as a versatile facility for developing and demonstrating, in hardware, the future technologies of wave front sensing and control algorithms for active optical systems. The testbed includes a source projector for a broadband point-source and a suite of extended scene targets, a dispersed fringe sensor, a Shack-Hartmann camera, and an imaging camera capable of phase retrieval wavefront sensing. The testbed also provides two easily accessible conjugated pupil planes which can accommodate the active optical devices such as fast steering mirror, deformable mirror, and segmented mirrors. In this paper, we describe the testbed optical design, testbed configurations and capabilities, as well as the initial results from the testbed hardware integrations and tests.

  20. Quality Control Using Optical Probe Arrays

    NASA Astrophysics Data System (ADS)

    Stewart, Robert M.

    1989-01-01

    Low cost, optical probes, can be combined into an inspection array, and the go/no-go outputs can be analyzed by a high speed programmable logic controller (PLC). The PLC can be remotely addressed to change the desired level of quality control. The PLC can provide on-line data for blow-by-blow statistical process control (SPC).

  1. [Quality control of printed patient information].

    PubMed

    Herm, Kerstin; Linden, Michael

    2013-05-01

    Printed material is an important part in patient information and is called bibliotherapy. It is subject to quality control similar to any other types of treatment. This paper presents an outline of important quality criteria and methods of quality control. Important quality criteria are: (a) Correctness and validity of content evaluated by mentioning the expertise of the authors, appraisal through external experts, reference to scientific literature, and empirical tests of the content, (b) Readability in respect to text structure measured by the "Flesch-Reading-Ease-Formula" supported by fair graphical design including fond and structure of text, (c) Comprehensibility tested by feedback of patients or standardized by the Hamburg comprehensibility rating, (d) Utility including securing availability, acceptance, differential indication and use. Writing and publication of patient leaflets must be accompanied by quality control measures. PMID:23446824

  2. Sampling for advanced overlay process control

    NASA Astrophysics Data System (ADS)

    Choi, DongSub; Izikson, Pavel; Sutherland, Doug; Sherman, Kara; Manka, Jim; Robinson, John C.

    2008-03-01

    Overlay metrology and control have been critical for successful advanced microlithography for many years, and are taking on an even more important role as time goes on. Due to throughput constraints it is necessary to sample only a small subset of overlay metrology marks, and typical sample plans are static over time. Standard production monitoring and control involves measuring sufficient samples to calculate up to 6 linear correctables. As design rules shrink and processing becomes more complex, however, it is necessary to consider higher order modeled terms for control, fault detection, and disposition. This in turn, requires a higher level of sampling. Due to throughput concerns, however, careful consideration is needed to establish a base-line sampling, and higher levels of sampling can be considered on an exception-basis based on automated trigger mechanisms. The goal is improved scanner control and lithographic cost of ownership. This study addresses tools for establishing baseline sampling as well as motivation and initial results for dynamic sampling for application to higher order modeling.

  3. Quality Control Systems in Cardiac Aging

    PubMed Central

    Quarles, Ellen K; Dai, Dao-Fu; Tocchi, Autumn; Basisty, Nathan; Gitari, Lemuel; Rabinovitch, Peter S

    2015-01-01

    Cardiac aging is an intrinsic process that results in impaired cardiac function, along with cellular and molecular changes. These degenerative changes are intimately associated with quality control mechanisms. This review provides a general overview of the clinical and cellular changes which manifest in cardiac aging, and the quality control mechanisms involved in maintaining homeostasis and retarding aging. These mechanisms include autophagy, ubiquitin-mediated turnover, apoptosis, mitochondrial quality control and cardiac matrix homeostasis. Finally, we discuss aging interventions that have been observed to impact cardiac health outcomes. These include caloric restriction, rapamycin, resveratrol, GDF11, mitochondrial antioxidants and cardiolipin-targeted therapeutics. A greater understanding of the quality control mechanisms that promote cardiac homeostasis will help to understand the benefits of these interventions, and hopefully lead to further improved therapeutic modalities. PMID:25702865

  4. [Study thought of pharmaceutical preparations quality standards by dynamic quality control technology].

    PubMed

    Yu, Dan-Hong; Mao, Chen-Mei; Lv, Cheng-Zhe; Jin, Hui-Zhen; Yao, Xin; Jia, Xiao-Bin

    2014-07-01

    Pharmaceutical preparations, particularly as a "secret recipe" of traditional Chinese medicine in medical institutions, are the product of China's medical and health industry, and they are also an important means of competing of different medical institutions. Although pharmaceutical preparations have advantages and characteristics than institutes for drug and pharmaceutical companies, the quality standards of pharmaceutical preparations in medical institutions has not reached the desired level over the years. As we all know, the quality of pharmaceutical preparations is important to ensure the efficacy, especially under the environment of people pay more sttention on drug safety and effectiveness and contry increase emphasis on the stste of pharmaceutical preparations. In view of this, we will improve the grade, stability, and clinical efficacy of pharmaceutical preparations by the advanced equipment, testing instruments and the process dynamic quality control technology. Finally, we hope we can provide new ideas for the quality control of pharmaceutical preparations. PMID:25272516

  5. The Advanced Controls Program at Oak Ridge National Laboratory

    SciTech Connect

    Knee, H.E.; White, J.D.

    1990-01-01

    The Oak Ridge National Laboratory (ORNL), under sponsorship of the US Department of Energy (DOE), is conducting research that will lead to advanced, automated control of new liquid-metal-reactor (LMR) nuclear power plants. Although this program of research (entitled the Advanced Controls Program'') is focused on LMR technology, it will be capable of providing control design, test, and qualification capability for other advanced reactor designs (e.g., the advanced light water reactor (ALWR) and high temperature gas-cooled reactor (HTGR) designs), while also benefiting existing nuclear plants. The Program will also have applicability to complex, non-nuclear process control environments (e.g., petrochemical, aerospace, etc.). The Advanced Controls Program will support capabilities throughout the entire plant design life cycle, i.e., from the initial interactive first-principle dynamic model development for the process, systems, components, and instruments through advanced control room qualification. The current program involves five principal areas of research activities: (1) demonstrations of advanced control system designs, (2) development of an advanced controls design environment, (3) development of advanced control strategies, (4) research and development (R D) in human-system integration for advanced control system designs, and (5) testing and validation of advanced control system designs. Discussion of the research in these five areas forms the basis of this paper. Also included is a description of the research directions of the program. 8 refs.

  6. Advanced Emissions Control Development Program: Phase III

    SciTech Connect

    G.T. Amrhein; R.T. Bailey; W. Downs; M.J. Holmes; G.A. Kudlac; D.A. Madden

    1999-07-01

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. The project goal is to effectively control air toxic emissions through the use of conventional flue gas clean-up equipment such as electrostatic precipitators (ESPs), fabric filters (baghouses - BH), and wet flue gas desulfurization systems (WFGD). Development work concentrated on the capture of trace metals, fine particulate, hydrogen chloride and hydrogen fluoride, with an emphasis on the control of mercury. The AECDP project is jointly funded by the US Department of Energy's Federal Energy Technology Center (DOE), the Ohio Coal Development Office within the Ohio Department of Development (OCDO), and Babcock and Wilcox, a McDermott company (B and W). This report discusses results of all three phases of the AECDP project with an emphasis on Phase III activities. Following the construction and evaluation of a representative air toxics test facility in Phase I, Phase II focused on characterization of the emissions of mercury and other air toxics and the control of these emissions for typical operating conditions of conventional flue gas clean-up equipment. Some general comments that can be made about the control of air toxics while burning a high-sulfur bituminous coal are as follows: (1) particulate control devices such as ESP's and baghouses do a good job of removing non-volatile trace metals, (2) particulate control devices (ESPs and baghouses) effectively remove the particulate-phase mercury, but the particulate-phase mercury was only a small fraction of the total for the coals tested, (3) wet scrubbing can effectively remove hydrogen chloride and hydrogen fluoride, and (4) wet scrubbers show good potential for the removal of mercury when operated under certain conditions, however, for certain applications, system enhancements can be required to achieve high

  7. Sampling for advanced overlay process control

    NASA Astrophysics Data System (ADS)

    Kato, Cindy; Kurita, Hiroyuki; Izikson, Pavel; Robinson, John C.

    2009-03-01

    Overlay metrology and control have been critical for successful advanced microlithography for many years, and are taking on an even more important role as time goes on. Due to throughput constraints it is necessary to sample only a small subset of overlay metrology marks, and typical sample plans are static over time. Standard production monitoring and control involves measuring sufficient samples to calculate up to 6 linear correctables. As design rules shrink and processing becomes more complex, however, it is necessary to consider higher order models with additional degrees of freedom for control, fault detection, and disposition. This in turn, requires a higher level of sampling and a careful consideration of flyer removal. Due to throughput concerns, however, careful consideration is needed to establish a baseline sampling plan using rigorous statistical methods. This study focuses on establishing a 3x nm node immersion lithography production-worthy sampling plan for 3rd order modeling, verification of the accuracy, and proof of robustness of the sampling. In addition we discuss motivation for dynamic sampling for application to higher order modeling.

  8. Quality control of automated cell counters.

    PubMed

    Cembrowski, George S; Clarke, Gwen

    2015-03-01

    The hematology analyzers of today provide more reproducible analyses compared with those of a few decades ago, necessitating an evolution in hematology quality practices. The improved performance allows use of simple quality control rules. This improved performance also renders the repeat analysis of critical value specimens non value added. Some of the patient averaging techniques have become outmoded and need to be replaced by less complicated calculations but with truncation of predictable outlying populations. The ready availability of comparative peer quality control values helps to improve analyzer precision and accuracy, and simplifies instrument validation and calibration. PMID:25676372

  9. Advanced Noise Control Fan Aerodynamic Performance

    NASA Technical Reports Server (NTRS)

    Bozak, Richard F., Jr.

    2009-01-01

    The Advanced Noise Control Fan at the NASA Glenn Research Center is used to experimentally analyze fan generated acoustics. In order to determine how a proposed noise reduction concept affects fan performance, flow measurements can be used to compute mass flow. Since tedious flow mapping is required to obtain an accurate mass flow, an equation was developed to correlate the mass flow to inlet lip wall static pressure measurements. Once this correlation is obtained, the mass flow for future configurations can be obtained from the nonintrusive wall static pressures. Once the mass flow is known, the thrust and fan performance can be evaluated. This correlation enables fan acoustics and performance to be obtained simultaneously without disturbing the flow.

  10. [The quality of biological information: standardization and quality control].

    PubMed

    Giampaoli, S; Muti, P

    1992-01-01

    Some procedures and methods for the measurement of cardiovascular risk factor are described; in particular of anthropometric measurements (weight, height, arm circumference, wrist circumference, hip circumference) of blood pressure, of electrocardiogram and of blood samples for the preservation of biological specimens. Some advice for the quality control during screening activities are reported. PMID:1492736

  11. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROGRAMS (CONTINUED) GUIDELINES ESTABLISHING TEST PROCEDURES FOR THE ANALYSIS OF POLLUTANTS § 136.7 Quality... referred to as a spiked blank, or laboratory control sample (LCS); (v) Matrix spike (MS) and matrix spike duplicate (MSD), or laboratory fortified matrix (LFM) and LFM duplicate, may be used for suspected...

  12. QUALITY ASSURANCE AND QUALITY CONTROL FOR RADIOCHEMICAL ANALYSES AND MEASUREMENTS

    EPA Science Inventory

    Require that each batch of samples analyzed be accompanied by appropriate quality control samples to evaluate accuracy and precision of the results. Require a documented data review and validation process by a minimum of three people before data is released to the client. Requi...

  13. Quality of life and the treatment of advanced lung cancer.

    PubMed

    Plunkett, Tim A; Chrystal, Kathryn F; Harper, Peter G

    2003-07-01

    Lung cancer is the leading cause of cancer deaths worldwide, with the majority of patients presenting with advanced disease. Despite the introduction of newer therapeutic agents and modest survival improvement, the overall prognosis for these patients is poor. The goals of therapy should therefore include improvement in quality of life (QOL), palliation of symptoms, and prolongation of survival. Quality of life has now become recognized as an important outcome measure for cancer therapy. Quality-of-life endpoints are being increasingly incorporated into clinical trials of newer agents to further define meaningful response. The assessment of QOL involves comprehensive measurement tools that address the physical, social, functional, and emotional well-being of the patient. Such measurements should be easy to use, meaningful, and relevant to the patients and clinician. Although these measures assess the longitudinal impact of treatment on QOL, pretreatment QOL scores may also be an important prognostic factor for survival in patients with lung carcinoma. This article reviews QOL measures and the data for QOL benefits from therapy in patients with advanced small-cell and non-small-cell lung cancer. PMID:14596700

  14. [Internal Quality Control and External Quality Assessment on POCT].

    PubMed

    Kuwa, Katsuhiko

    2015-02-01

    The quality management (QM) of POCT summarizes its internal quality control (IQC) and external quality assessment (EQA). For QM requirements in POCT, ISO 22870-Point-of-care testing (POCT) -Requirements for quality and competence and ISO 15189-Medical laboratories-Requirements for quality and competence, it is performed under the guidance of the QM committee. The role of the POC coordinator and/or medical technologist of the clinical laboratory is important. On measurement performance of POCT devices, it is necessary to confirm data on measurement performance from the manufacturer other than those in the inserted document. In the IQC program, the checking and control of measurement performance are the targets. On measurements of QC samples by the manufacturer, it is essential to check the function of devices. In addition, regarding the EQA program, in 2 neighboring facilities, there is an effect to confirm the current status of measurement and commutability assessment in these laboratories using whole blood along with residual blood samples from daily examinations in the clinical laboratory. PMID:26529974

  15. Knowledge Management Platform in Advanced Product Quality Planning

    NASA Astrophysics Data System (ADS)

    Chiliban, Bogdan; Baral, Lal Mohan; Kifor, Claudiu

    2014-12-01

    Knowledge is an essential part of organizational competitiveness. This vital resource must be managed correctly within organizations in order to achieve desired performance levels within all undertakings. The process of managing knowledge is a very difficult one due to the illusive nature of the resource itself. Knowledge is stored within every aspect of an organization starting from people and ending with documents and processes. The Knowledge Management Platform is designed as a facilitator for managers and employees in all endeavours knowledge related within the Advanced Product Quality Planning Procedure

  16. Control Software for Advanced Video Guidance Sensor

    NASA Technical Reports Server (NTRS)

    Howard, Richard T.; Book, Michael L.; Bryan, Thomas C.

    2006-01-01

    Embedded software has been developed specifically for controlling an Advanced Video Guidance Sensor (AVGS). A Video Guidance Sensor is an optoelectronic system that provides guidance for automated docking of two vehicles. Such a system includes pulsed laser diodes and a video camera, the output of which is digitized. From the positions of digitized target images and known geometric relationships, the relative position and orientation of the vehicles are computed. The present software consists of two subprograms running in two processors that are parts of the AVGS. The subprogram in the first processor receives commands from an external source, checks the commands for correctness, performs commanded non-image-data-processing control functions, and sends image data processing parts of commands to the second processor. The subprogram in the second processor processes image data as commanded. Upon power-up, the software performs basic tests of functionality, then effects a transition to a standby mode. When a command is received, the software goes into one of several operational modes (e.g. acquisition or tracking). The software then returns, to the external source, the data appropriate to the command.

  17. A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis

    PubMed Central

    2013-01-01

    BACKGROUND Sildenafil, a phosphodiesterase-5 inhibitor, may preferentially improve blood flow to well-ventilated regions of the lung in patients with advanced idiopathic pulmonary fibrosis, which could result in improvements in gas exchange. We tested the hypothesis that treatment with sildenafil would improve walk distance, dyspnea, and quality of life in patients with advanced idiopathic pulmonary fibrosis, defined as a carbon monoxide diffusion capacity of less than 35% of the predicted value. METHODS We conducted a double-blind, randomized, placebo-controlled trial of sildenafil in two periods. The first period consisted of 12 weeks of a double-blind comparison between sildenafil and a placebo control. The primary outcome was the proportion of patients with an increase in the 6-minute walk distance of 20% or more. Key secondary outcomes included changes in oxygenation, degree of dyspnea, and quality of life. The second period was a 12-week open-label evaluation involving all patients receiving sildenafil. RESULTS A total of 180 patients were enrolled in the study. The difference in the primary outcome was not significant, with 9 of 89 patients (10%) in the sildenafil group and 6 of 91 (7%) in the placebo group having an improvement of 20% or more in the 6-minute walk distance (P = 0.39). There were small but significant differences in arterial oxygenation, carbon monoxide diffusion capacity, degree of dyspnea, and quality of life favoring the sildenafil group. Serious adverse events were similar in the two study groups. CONCLUSIONS This study did not show a benefit for sildenafil for the primary outcome. The presence of some positive secondary outcomes creates clinical equipoise for further research. (Funded by the National Heart, Lung, and Blood Institute and others; ClinicalTrials.gov number, NCT00517933.) PMID:20484178

  18. Quality control by a mobile molecular workshop: Quality versus quantity

    NASA Astrophysics Data System (ADS)

    Sharma, Ajeet K.; Chowdhury, Debashish

    2010-09-01

    Ribosome is a molecular machine that moves on a messenger RNA (mRNA) track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we argue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products, while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechanochemical coupling. We suggest experiments for testing some of the ideas presented here.

  19. Harmonisation Initiatives of Copernicus Data Quality Control

    NASA Astrophysics Data System (ADS)

    Vescovi, F. D.; Lankester, T.; Coleman, E.; Ottavianelli, G.

    2015-04-01

    The Copernicus Space Component Data Access system (CSCDA) incorporates data contributions from a wide range of satellite missions. Through EO data handling and distribution, CSCDA serves a set of Copernicus Services related to Land, Marine and Atmosphere Monitoring, Emergency Management and Security and Climate Change. The quality of the delivered EO products is the responsibility of each contributing mission, and the Copernicus data Quality Control (CQC) service supports and complements such data quality control activities. The mission of the CQC is to provide a service of quality assessment on the provided imagery, to support the investigation related to product quality anomalies, and to guarantee harmonisation and traceability of the quality information. In terms of product quality control, the CQC carries out analysis of representative sample products for each contributing mission as well as coordinating data quality investigation related to issues found or raised by Copernicus users. Results from the product analysis are systematically collected and the derived quality reports stored in a searchable database. The CQC service can be seen as a privileged focal point with unique comparison capacities over the data providers. The comparison among products from different missions suggests the need for a strong, common effort of harmonisation. Technical terms, definitions, metadata, file formats, processing levels, algorithms, cal/val procedures etc. are far from being homogeneous, and this may generate inconsistencies and confusion among users of EO data. The CSCDA CQC team plays a significant role in promoting harmonisation initiatives across the numerous contributing missions, so that a common effort can achieve optimal complementarity and compatibility among the EO data from multiple data providers. This effort is done in coordination with important initiatives already working towards these goals (e.g. INSPIRE directive, CEOS initiatives, OGC standards, QA4EO

  20. Manufacture and quality control of interconnecting wire hardnesses, Volume 1

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A standard is presented for manufacture, installation, and quality control of eight types of interconnecting wire harnesses. The processes, process controls, and inspection and test requirements reflected are based on acknowledgment of harness design requirements, acknowledgment of harness installation requirements, identification of the various parts, materials, etc., utilized in harness manufacture, and formulation of a typical manufacturing flow diagram for identification of each manufacturing and quality control process, operation, inspection, and test. The document covers interconnecting wire harnesses defined in the design standard, including type 1, enclosed in fluorocarbon elastomer convolute, tubing; type 2, enclosed in TFE convolute tubing lines with fiberglass braid; type 3, enclosed in TFE convolute tubing; and type 5, combination of types 3 and 4. Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated.

  1. Advanced Control and Power System (ACAPS) Technology Program

    NASA Technical Reports Server (NTRS)

    Keckler, C. R.; Groom, N. J.

    1983-01-01

    The advanced control and power system (ACAPS) program is to establish the technology necessary to satisfy space station and related large space structures requirements for efficient, reliable, and cost effective energy storage and attitude control. Technology advances in the area of integrated flywheel systems capable of performing the dual functions of energy storage and attitude control are outlined.

  2. Advanced lung disease: quality of life and role of palliative care.

    PubMed

    Gilbert, Christopher R; Smith, Cecilia M

    2009-02-01

    Advanced restrictive lung diseases remain a challenge for both the clinician and patient alike. Because there are few available treatment options that prolong survival for patients with diseases such as idiopathic pulmonary fibrosis, improvement in quality of life and palliation of significant symptoms become realistic treatment goals. Several validated instruments that assess quality of life and health-related quality of life have demonstrated the dramatic impact that lung disease has on patients. Quality-of-life assessments of patients with interstitial lung disease have commonly cited respiratory complaints as problematic, but other distressing symptoms often not addressed include fear, social isolation, anxiety, and depression. Not only do respiratory symptoms limit this patient population, but the awareness of decreased independence and ability for social participation also has an impact on the quality of life. Some patients describe a deepened spiritual well-being during their disease process; however, many patients' mental health suffers with experiences of fear, worry, anxiety, and panic. Many patients express desire for more attention to end-of-life issues from their physicians. Fears of worsening symptoms and suffocation exist with an expressed desire by most to die peacefully with symptom control. Interventions to improve quality of life are largely directed at symptom control. Pharmacologic and nonpharmacologic interventions have been helpful in relieving dyspnea. Studies have demonstrated that the use of supplemental oxygen in the face of advancing hypoxemia can have both positive and negative effects on quality of life. Patients using nasal prongs describe feelings of self-consciousness, embarrassment, and social withdrawal. Pulmonary rehabilitation is recommended, with some studies noting increased quality-of-life scores and decreased sensations of dyspnea. Sleep deprivation and poor sleep quality also have a negative impact on quality of life

  3. Structureborne noise control in advanced turboprop aircraft

    NASA Astrophysics Data System (ADS)

    Loeffler, Irvin J.

    1987-01-01

    Structureborne noise is discussed as a contributor to propeller aircraft interior noise levels that are nonresponsive to the application of a generous amount of cabin sidewall acoustic treatment. High structureborne noise levels may jeopardize passenger acceptance of the fuel-efficient high-speed propeller transport aircraft designed for cruise at Mach 0.65 to 0.85. These single-rotation tractor and counter-rotation tractor and pusher propulsion systems will consume 15 to 30 percent less fuel than advanced turbofan systems. Structureborne noise detection methodologies and the importance of development of a structureborne noise sensor are discussed. A structureborne noise generation mechanism is described in which the periodic components or propeller swirl produce periodic torques and forces on downstream wings and airfoils that are propagated to the cabin interior as noise. Three concepts for controlling structureborne noise are presented: (1) a stator row swirl remover, (2) selection of a proper combination of blade numbers in the rotor/stator system of a single-rotation propeller, and the rotor/rotor system of a counter-rotation propeller, and (3) a tuned mechanical absorber.

  4. Impact of Advance Control on Microturbine Generation System Performance

    NASA Astrophysics Data System (ADS)

    Kamil Mat Hussin, Ahmad; Zamri Che Wanik, Mohd

    2013-06-01

    Advance control employed in microturbine generation system (MTGS) is expected to improve its performance in responding to grid faults. This paper compares the effect of advance control of MTGS power conversion topology on the performance in riding through the grid faults. The analysis and investigation study through simulation shows there is no significant different on MTGS output performance even advance control is employed for its rectifier.

  5. HPLC for quality control of polyimides

    NASA Technical Reports Server (NTRS)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  6. Quality control in the secretory assembly line.

    PubMed Central

    Helenius, A

    2001-01-01

    As a rule, only proteins that have reached a native, folded and assembled structure are transported to their target organelles and compartments within the cell. In the secretory pathway of eukaryotic cells, this type of sorting is particularly important. A variety of molecular mechanisms are involved that distinguish between folded and unfolded proteins, modulate their intracellular transport, and induce degradation if they fail to fold. This phenomenon, called quality control, occurs at several levels and involves different types of folding sensors. The quality control system provides a stringent and versatile molecular sorting system that guaranties fidelity of protein expression in the secretory pathway. PMID:11260794

  7. [Quality control of Maca (Lepidium meyenii)].

    PubMed

    Shu, Ji-cheng; Cui, Hang-qing; Huang, Ying-zheng; Huang, Xiao-ying; Yang, Ming

    2015-12-01

    To control the quality of Maca, the quality standard was established in this study. According to the methods recorded in the Appendix of Chinese Pharmacopoeia (2010 Edition), the water, extract, total ash, acid insoluble substance, and heavy metals inspections in Lepidium meyenii were carried out. N-benzyl-9Z, 12Z-octadecadienamide in L. meyenii was identified by TLC, and it was determined by HPLC. The results showed that the N-benzyl-9Z, 12Z-octadecadienamide identification of TLC was a strong mark and specificity. In content determination experiment, the linearity of N-benzyl-9Z, 12Z-octadecadienamide was in the range of 0.01-2 microg (r = 0.9998), and the average recovery (n=9) was 99.27% (RSD 2.0%). The methods were simple, accurate, with good reproducibility. It is suitable for quality control L. meyenii. PMID:27141660

  8. Outsourcing University Degrees: Implications for Quality Control

    ERIC Educational Resources Information Center

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  9. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  10. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  11. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  12. Acoustic resonance techniques for quality control

    SciTech Connect

    Sinha, D.N.

    1992-09-01

    Acoustic resonance based nondestructive techniques are described that can be used for both process and quality control in manufacturing. The Acoustic Resonance Spectroscopy (AS) technique is highlighted for its capability in fluid property (flow, density, viscosity, and speed of sound) monitoring. Possible applications of these noninvasive techniques for textile manufacturing are pointed out.

  13. Acoustic resonance techniques for quality control

    SciTech Connect

    Sinha, D.N.

    1992-01-01

    Acoustic resonance based nondestructive techniques are described that can be used for both process and quality control in manufacturing. The Acoustic Resonance Spectroscopy (AS) technique is highlighted for its capability in fluid property (flow, density, viscosity, and speed of sound) monitoring. Possible applications of these noninvasive techniques for textile manufacturing are pointed out.

  14. Quality Control & Design in Science Learning

    ERIC Educational Resources Information Center

    Sumrall, William J.; Schillinger, Don

    2003-01-01

    One area of science education that is, at times, neglected involves lessons on technological concepts of these principles--designing, testing, and quality control. Instead, a focus upon science concepts from a pure, and unapplied, perspective is the norm. Thus, while students may learn the equation "mass divided by volume equals density," the…

  15. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; filing requirements. 84.40... Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval or... proposed quality control plan which shall be designed to assure the quality of respiratory...

  16. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  17. 21 CFR 211.22 - Responsibilities of quality control unit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or...

  18. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  19. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control plans; filing requirements. 84.40... Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval or... proposed quality control plan which shall be designed to assure the quality of respiratory...

  20. Practicing Quality Control in a Bioanalytical Experiment

    NASA Astrophysics Data System (ADS)

    Marcos, Juliana; Ríos, Angel; Valcárcel, Miguel

    1995-10-01

    The quality of analytical results frequently requires assessment, which has fostered treatment of this subject in a host of chemical books for students. Accordingly, new experiments need to be devised in order to help students adapt to it. This paper presents a straightforward exercise to demonstrate how quality control and the analysis of variance technique are implemented in practice. The exercise also is attractive because the analyte (chlorophyl) is determined in real samples (plants) that students can collect by themselves. In this way, they can realize the significance of sampling and learn how to do it properly.

  1. Quality and Control of Water Vapor Winds

    NASA Technical Reports Server (NTRS)

    Jedlovec, Gary J.; Atkinson, Robert J.

    1996-01-01

    Water vapor imagery from the geostationary satellites such as GOES, Meteosat, and GMS provides synoptic views of dynamical events on a continual basis. Because the imagery represents a non-linear combination of mid- and upper-tropospheric thermodynamic parameters (three-dimensional variations in temperature and humidity), video loops of these image products provide enlightening views of regional flow fields, the movement of tropical and extratropical storm systems, the transfer of moisture between hemispheres and from the tropics to the mid- latitudes, and the dominance of high pressure systems over particular regions of the Earth. Despite the obvious larger scale features, the water vapor imagery contains significant image variability down to the single 8 km GOES pixel. These features can be quantitatively identified and tracked from one time to the next using various image processing techniques. Merrill et al. (1991), Hayden and Schmidt (1992), and Laurent (1993) have documented the operational procedures and capabilities of NOAA and ESOC to produce cloud and water vapor winds. These techniques employ standard correlation and template matching approaches to wind tracking and use qualitative and quantitative procedures to eliminate bad wind vectors from the wind data set. Techniques have also been developed to improve the quality of the operational winds though robust editing procedures (Hayden and Veldon 1991). These quality and control approaches have limitations, are often subjective, and constrain wind variability to be consistent with model derived wind fields. This paper describes research focused on the refinement of objective quality and control parameters for water vapor wind vector data sets. New quality and control measures are developed and employed to provide a more robust wind data set for climate analysis, data assimilation studies, as well as operational weather forecasting. The parameters are applicable to cloud-tracked winds as well with minor

  2. Advanced control technology for LSST antennas

    NASA Technical Reports Server (NTRS)

    Lin, Y. H.

    1981-01-01

    The control technology for the realization of large space system technology (LSST) antenna systems was identified and developed. Emphasis was directed at the control of LSST wrap-rib offset-feed antenna. The overall dynamic and control performance of offset-feed antenna was evaluated. Quantitative definitions of control problems were provided and control concepts for future development were identified.

  3. Laboratory quality control based on risk management.

    PubMed

    Nichols, James H

    2011-01-01

    Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives). Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed. PMID:21623049

  4. Open architecture controllers for advanced manufacturing

    SciTech Connect

    Gore, R.A.

    1994-03-01

    The application of intelligent control systems to the real world of machining and manufacturing will benefit form the presence of open architecture control systems on the machines or the processes. The ability to modify the control system as the process or product changes can be essential to the success of the application of neural net or fuzzy logic controllers. The effort at Los Alamos to obtain a commercially available open architecture machine tool controller is described.

  5. Protein quality control in the nucleus.

    PubMed

    Jones, Ramon D; Gardner, Richard G

    2016-06-01

    The nucleus is the repository for the eukaryotic cell's genetic blueprint, which must be protected from harm to ensure survival. Multiple quality control (QC) pathways operate in the nucleus to maintain the integrity of the DNA, the fidelity of the DNA code during replication, its transcription into mRNA, and the functional structure of the proteins that are required for DNA maintenance, mRNA transcription, and other important nuclear processes. Although we understand a great deal about DNA and RNA QC mechanisms, we know far less about nuclear protein quality control (PQC) mechanisms despite that fact that many human diseases are causally linked to protein misfolding in the nucleus. In this review, we discuss what is known about nuclear PQC and we highlight new questions that have emerged from recent developments in nuclear PQC studies. PMID:27015023

  6. Quality control analytical methods: strategies to ensure a robust quality-control microbiology program.

    PubMed

    Griffiths, Tricia; Connors, Anne

    2013-01-01

    As the regulatory environment for compounding pharmacies continues to evolve, facilities can take immediate steps to strengthen their quality-control microbiology and environmental monitoring programs. Robust programs that are timely, comprehensive, and effective will minimize risk and help support positive patient outcomes. This article provides a roadmap for putting in place a robust quality-control microbiology program in the face of United States Pharmacopeia Chapter 797 standards, and highlights several technologies for environmental monitoring that support a successful program. PMID:23696174

  7. Towards quality control of food using terahertz

    NASA Astrophysics Data System (ADS)

    Ung, B. S.-Y.; Fischer, B. M.; Ng, B. W.-H.; Abbott, D.

    2007-12-01

    Terahertz radiation or T-rays, show promise in quality control of food products. As T-rays are inherently sensitive to water, they are very suitable for moisture detection. This proves to be a valuable asset in detecting the moisture content of dried food, a critical area for some products. As T-rays are transparent to plastics, food additives can also be probed through the packaging, providing checks against a manufacturer's claims, such as the presence of certain substances in foods.

  8. How intense quality control improves hydraulic fracturing

    SciTech Connect

    Ely, J.W.

    1996-11-01

    Not unlike the subject of Forced Closure, Intense Quality Control is probably misnamed. What actually is discussed in this article is pilot testing of the fracturing fluids actually pumped at in-situ conditions of temperature and shear. Presented here is development of the need for onsite testing, equipment used, shear and viscosity curves from several jobs showing what went wrong that would otherwise not have been known, and a discussion of borate gel fluids.

  9. Experiment-Based Teaching in Advanced Control Engineering

    ERIC Educational Resources Information Center

    Precup, R.-E.; Preitl, S.; Radac, M.-B.; Petriu, E. M.; Dragos, C.-A.; Tar, J. K.

    2011-01-01

    This paper discusses an experiment-based approach to teaching an advanced control engineering syllabus involving controlled plant analysis and modeling, control structures and algorithms, real-time laboratory experiments, and their assessment. These experiments are structured around the representative case of the longitudinal slip control of an…

  10. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  11. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  12. 7 CFR 58.928 - Quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  13. 7 CFR 58.928 - Quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  14. 7 CFR 58.642 - Quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  15. 7 CFR 58.642 - Quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  16. Advanced control technology for LSST platform

    NASA Technical Reports Server (NTRS)

    Edmunds, R. S.

    1981-01-01

    Basic technology in the design, mechanization, and analysis of control systems for large flexible space structures was examined. The focus of the platform control effort was on pointing control. The reason for this emphasis was because of the unique problems in this area posed by multiple independent experiment packages operating simultaneously on a single platform. Attitude control and stationkeeping were also addressed for future consideration.

  17. Smart Engines Via Advanced Model Based Controls

    SciTech Connect

    Allain, Marc

    2000-08-20

    A ''new'' process for developing control systems - Less engine testing - More robust control system - Shorter development cycle time - ''Smarter'' approach to engine control - On-board models describe engine behavior - Shorter, systematic calibration process - Customer and legislative requirements designed-in.

  18. Controlling template erosion with advanced cleaning methods

    NASA Astrophysics Data System (ADS)

    Singh, SherJang; Yu, Zhaoning; Wähler, Tobias; Kurataka, Nobuo; Gauzner, Gene; Wang, Hongying; Yang, Henry; Hsu, Yautzong; Lee, Kim; Kuo, David; Dress, Peter

    2012-03-01

    We studied the erosion and feature stability of fused silica patterns under different template cleaning conditions. The conventional SPM cleaning is compared with an advanced non-acid process. Spectroscopic ellipsometry optical critical dimension (SE-OCD) measurements were used to characterize the changes in pattern profile with good sensitivity. This study confirmed the erosion of the silica patterns in the traditional acid-based SPM cleaning mixture (H2SO4+H2O2) at a rate of ~0.1nm per cleaning cycle. The advanced non-acid clean process however only showed CD shift of ~0.01nm per clean. Contamination removal & pattern integrity of sensitive 20nm features under MegaSonic assisted cleaning is also demonstrated.

  19. Advanced control evaluation for structures (ACES) programs

    NASA Technical Reports Server (NTRS)

    Pearson, Jerome; Waites, Henry

    1988-01-01

    The ACES programs are a series of past, present, and future activities at the Marshall Space Flight Center (MSFC) Ground facility for Large Space Structure Control Verification (GF/LSSCV). The main objectives of the ACES programs are to implement control techniques on a series of complex dynamical systems, to determine the control/structure interaction for the control techniques, and to provide a national facility in which dynamics and control verification can be effected. The focus is on these objectives and how they are implemented under various engineering and economic constraints. Future plans that will be effected in upcoming ACES programs are considered.

  20. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... and Process Control System: Requirements for Quality Control § 111.117 What quality control operations are required for equipment, instruments, and controls? Quality control operations for equipment... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What quality control operations are required...

  1. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false What quality control operations are required for... and Process Control System: Requirements for Quality Control § 111.117 What quality control operations are required for equipment, instruments, and controls? Quality control operations for...

  2. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false What quality control operations are required for... and Process Control System: Requirements for Quality Control § 111.117 What quality control operations are required for equipment, instruments, and controls? Quality control operations for...

  3. Optimization and quality control of computed radiography

    NASA Astrophysics Data System (ADS)

    Willis, Charles E.; Weiser, John C.; Leckie, Robert G.; Romlein, John R.; Norton, Gary S.

    1994-05-01

    Computed radiography (CR) is a relatively new technique for projection radiography. Few hospitals have CR devices in routine service and only a handful have more than one CR unit. As such, the clinical knowledge base does not yet exist to establish quality control (QC) procedures for CR devices. Without assurance that CR systems are operating within nominal limits, efforts to optimize CR performance are limited in value. A complete CR system includes detector plates that vary in response, cassettes, an electro-optical system for developing the image, computer algorithms for processing the raw image, and a hard copy output device. All of these subsystems are subject to variations in performance that can degrade image quality. Using CR manufacturer documentation, we have defined acceptance protocols for two different Fuji CR devices, the FCR 7000 and the AC1+, and have applied these tests to ten individual machines. We have begun to establish baseline performance measures and to determine measurement frequencies. CR QC is only one component of the overall quality control for totally digital radiology departments.

  4. Advanced rotorcraft control using parameter optimization

    NASA Technical Reports Server (NTRS)

    Vansteenwyk, Brett; Ly, Uy-Loi

    1991-01-01

    A reliable algorithm for the evaluation of a quadratic performance index and its gradients with respect to the controller design parameters is presented. The algorithm is part of a design algorithm for an optimal linear dynamic output feedback controller that minimizes a finite time quadratic performance index. The numerical scheme is particularly robust when it is applied to the control law synthesis for systems with densely packed modes and where there is a high likelihood of encountering degeneracies in the closed loop eigensystem. This approach through the use of a accurate Pade series approximation does not require the closed loop system matrix to be diagonalizable. The algorithm has been included in a control design package for optimal robust low order controllers. Usefulness of the proposed numerical algorithm has been demonstrated using numerous practical design cases where degeneracies occur frequently in the closed loop system under an arbitrary controller design initialization and during the numerical search.

  5. Model-free adaptive control of advanced power plants

    SciTech Connect

    Cheng, George Shu-Xing; Mulkey, Steven L.; Wang, Qiang

    2015-08-18

    A novel 3-Input-3-Output (3.times.3) Model-Free Adaptive (MFA) controller with a set of artificial neural networks as part of the controller is introduced. A 3.times.3 MFA control system using the inventive 3.times.3 MFA controller is described to control key process variables including Power, Steam Throttle Pressure, and Steam Temperature of boiler-turbine-generator (BTG) units in conventional and advanced power plants. Those advanced power plants may comprise Once-Through Supercritical (OTSC) Boilers, Circulating Fluidized-Bed (CFB) Boilers, and Once-Through Supercritical Circulating Fluidized-Bed (OTSC CFB) Boilers.

  6. Advanced Combustion and Emission Control Technical Team Roadmap

    SciTech Connect

    2013-06-01

    The Advanced Combustion and Emission Control (ACEC) Technical Team is focused on removing technical barriers to the commercialization of advanced, high-efficiency, emission-compliant internal combustion (IC) engines for light-duty vehicle powertrains (i.e., passenger car, minivan, SUV, and pickup trucks).

  7. Advanced dc-Traction-Motor Control System

    NASA Technical Reports Server (NTRS)

    Vittone, O.

    1985-01-01

    Motor-control concept for battery-powered vehicles includes stateof-the-art power-transistor switching and separate excitation of motor windings in traction and regenerative braking. Switching transistors and other components of power-conditioning subsystem operate under control of computer that coordinates traction, braking, and protective functions.

  8. Quality Assurance and Quality Control in Point-of-Care Testing.

    PubMed

    Newman, Ashleigh W; Behling-Kelly, Erica

    2016-03-01

    With advancements in the standard of care in veterinary medicine and instrument technology, performing in-house laboratory work on a variety of point-of-care instruments, ranging from glucometers to benchtop chemistry analyzers, has become increasingly commonplace. However, the ability of an instrument to perform a test does not guarantee that those results are accurate. Ensuring that your in-clinic laboratory is providing reliable data requires a comprehensive plan that encompasses both common sense practices aimed at preventing errors at each stage of the testing process, as well as standard operating procedures to validate and monitor analyzer performance. These 2 arms of the plan are known as quality assurance and quality control. Although these concepts are typically out of the comfort zone for veterinarians, just as the thought of business management may deter some veterinarians from practice ownership, it is not beyond the capabilities of veterinarians to learn, understand, and incorporate them into their practice. The objectives of this article are to convey the importance of quality assurance and quality control, walk you through the American Society for Veterinary Clinical Pathology guidelines on this topic, and provide direction to additional resources for further education on this topic, all with the focus on point-of-care testing in the in-clinic laboratory. PMID:27451043

  9. Mammographic equipment, technique, and quality control

    SciTech Connect

    Friedrich, M.A. )

    1991-08-01

    The most important improvements in mammographic technique were the introduction of single- or double-emulsion high-contrast film-screen combinations for mammography, the use of a specially designed low-kilovoltage Bucky grid to reduce scattered radiation, and the introduction of smaller focal spots to improve imaging geometry. Magnification techniques, especially the spot-film technique, yields clearer delineation of high-contrast microcalcifications. Dedicated mammographic equipment with specially designed x-ray tubes is necessary for modern high-quality mammography. However, in many modern mammographic units, the automatic exposure controller still fails to provide appropriate and constant optical film density over a wide range of tissue thickness and absorption. Extended-cycle processing of single-emulsion mammographic films can yield better image contrast and reduce exposure by up to 30%. Exposure times of less than 1 second are recommended to avoid the unnecessary higher doses caused by longer exposure times and reciprocity law failure. The wide dynamic range in mammography can be reduced by a beam equalization filter, and thus be better adapted to the decreased latitude of modern high-contrast mammographic screen-film systems. Mammographic film reading (detection of subtle microcalcifications) can be facilitated by modern computer evaluation of previously digitized mammograms. Standardization and assurance of image quality have been major challenges in the technical development of mammography. Different technical and anthropomorphic phantoms have been designed to measure and compare practical image quality. Detailed quality control measures have been developed. The benefit of a single or annual screening mammography, calculated in gained life expectancy, by far outweighs the relative risk for radiation-induced breast cancer. 22 references.

  10. The ATF (Advanced Toroidal Facility) Status and Control System

    SciTech Connect

    Baylor, L.R.; Devan, W.R.; Sumner, J.N.; Alban, A.M.

    1987-01-01

    The Advanced Toroidal Facility (ATF) Status and Control System (SCS) is a programmable controller-based state monitoring and supervisory control system. This paper describes the SCS implementation and its use of a host computer to run a commercially available software package that provides color graphic interactive displays, alarm logging, and archiving of state data.

  11. Status report on the Advanced Light Source control system

    SciTech Connect

    Magyary, S.; Chin, M.; Fahmie, M.; Lancaster, H.; Molinari, P.; Robb, A.; Timossi, C.; Young, J.

    1991-11-11

    This paper is a status report on the ADVANCED LIGHT SOURCE (ALS) control system. The current status, performance data, and future plans will be discussed. Manpower, scheduling, and costs issues are addressed.

  12. Advanced Topics in Wet-Weather Discharge Control

    EPA Science Inventory

    This report discusses four related but generally independent wet-weather flow (WWF) topic areas, namely: i) opportunities for advanced practices in WWF control technology, particularly as it applies to sewered systems; ii) tradeoffs between storage facilities (tanks) and enlarged...

  13. Attitude Control Subsystem for the Advanced Communications Technology Satellite

    NASA Technical Reports Server (NTRS)

    Hewston, Alan W.; Mitchell, Kent A.; Sawicki, Jerzy T.

    1996-01-01

    This paper provides an overview of the on-orbit operation of the Attitude Control Subsystem (ACS) for the Advanced Communications Technology Satellite (ACTS). The three ACTS control axes are defined, including the means for sensing attitude and determining the pointing errors. The desired pointing requirements for various modes of control as well as the disturbance torques that oppose the control are identified. Finally, the hardware actuators and control loops utilized to reduce the attitude error are described.

  14. Environmental quality control report. [Semiannual] report, July--December 1988

    SciTech Connect

    Bishop, C.T.

    1989-04-14

    This report presents the details of the Mound Laboratory EPA-NPDES Quality Assurance Program, the DOE Quality Assessment Program Results, Proficiency Environmental Testing Program and Plutonium in Urine Quality Control for 1988.

  15. Advanced control concepts. [for shuttle ascent vehicles

    NASA Technical Reports Server (NTRS)

    Sharp, J. B.; Coppey, J. M.

    1973-01-01

    The problems of excess control devices and insufficient trim control capability on shuttle ascent vehicles were investigated. The trim problem is solved at all time points of interest using Lagrangian multipliers and a Simplex based iterative algorithm developed as a result of the study. This algorithm has the capability to solve any bounded linear problem with physically realizable constraints, and to minimize any piecewise differentiable cost function. Both solution methods also automatically distribute the command torques to the control devices. It is shown that trim requirements are unrealizable if only the orbiter engines and the aerodynamic surfaces are used.

  16. Protein Quality Control and Degradation in Cardiomyocytes

    PubMed Central

    Wang, Xuejun; Su, Huabo; Ranek, Mark J.

    2008-01-01

    The heart is constantly under stress and cardiomyocytes face enormous challenges to correctly fold nascent polypeptides and keep mature proteins from denaturing. To meet the challenge, cardiomyocytes have developed multi-layered protein quality control (PQC) mechanisms which are carried out primarily by chaperones and ubiquitin-proteasome system mediated proteolysis. Autophagy may also participate in PQC in cardiomyocytes, especially under pathological conditions. Cardiac PQC often becomes inadequate in heart disease, which may play an important role in the development of congestive heart failure. PMID:18495153

  17. Distributed Sensor Architecture for Intelligent Control that Supports Quality of Control and Quality of Service

    PubMed Central

    Poza-Lujan, Jose-Luis; Posadas-Yagüe, Juan-Luis; Simó-Ten, José-Enrique; Simarro, Raúl; Benet, Ginés

    2015-01-01

    This paper is part of a study of intelligent architectures for distributed control and communications systems. The study focuses on optimizing control systems by evaluating the performance of middleware through quality of service (QoS) parameters and the optimization of control using Quality of Control (QoC) parameters. The main aim of this work is to study, design, develop, and evaluate a distributed control architecture based on the Data-Distribution Service for Real-Time Systems (DDS) communication standard as proposed by the Object Management Group (OMG). As a result of the study, an architecture called Frame-Sensor-Adapter to Control (FSACtrl) has been developed. FSACtrl provides a model to implement an intelligent distributed Event-Based Control (EBC) system with support to measure QoS and QoC parameters. The novelty consists of using, simultaneously, the measured QoS and QoC parameters to make decisions about the control action with a new method called Event Based Quality Integral Cycle. To validate the architecture, the first five Braitenberg vehicles have been implemented using the FSACtrl architecture. The experimental outcomes, demonstrate the convenience of using jointly QoS and QoC parameters in distributed control systems. PMID:25723145

  18. Advanced gel propulsion controls for kill vehicles

    NASA Astrophysics Data System (ADS)

    Yasuhara, W. K.; Olson, A.; Finato, S.

    1993-06-01

    A gel propulsion control concept for tactical applications is reviewed, and the status of the individual component technologies currently under development at the Aerojet Propulsion Division is discussed. It is concluded that a gel propellant Divert and Attitude Control Subsystem (DACS) provides a safe, insensitive munitions compliant alternative to current liquid Theater Missile Defense (TMD) DACS approaches. The gel kill vehicle (KV) control system packages a total impulse typical of a tactical weapon interceptor for the ground- or sea-based TMD systems. High density packaging makes it possible to increase firepower and to eliminate long-term high pressure gas storage associated with bipropellant systems. The integrated control subsystem technologies encompass solid propellant gas generators, insulated composite overwrapped propellant tanks, lightweight endoatmospheric thrusters, and insensitive munition gel propellants, which meet the requirements of a deployable, operationally safe KV.

  19. Evaluation of Water Quality Renovation by Advanced Soil-Based Wastewater Treatment Systems

    NASA Astrophysics Data System (ADS)

    Cooper, J.; Loomis, G.; Kalen, D.; Boving, T.; Morales, I.; DeLuca, J.; Amador, J.

    2013-12-01

    25% of US households utilize onsite wastewater treatment systems (OWTS) for wastewater management. Advanced technologies were designed to overcome the inadequate wastewater treatment by conventional OWTS in critical shallow water table areas, such as coastal zones, in order to protect ground water quality. In addition to the septic tank and soil drainfield that comprise a conventional OWTS, advanced systems claim improved water renovation with the addition of sand filtration, timed dosing controls, and shallow placement of the infiltrative zone. We determined water quality renovation functions under current water table and temperature conditions, in anticipation of an experiment to measure OWTS response to a climate change scenario of 30-cm increase in water table elevation and 4C temperature increase. Replicate (n=3) intact soil mesocosms were used to evaluate the effectiveness of drainfields with a conventional wastewater delivery (pipe-and-stone) compared to two types of pressurized, shallow narrow drainfield. Results under steady state conditions indicate complete removal of fecal coliform bacteria, phosphorus and BOD by all soil-based systems. By contrast, removal of total nitrogen inputs was 16% in conventional and 11% for both advanced drainfields. Effluent waters maintained a steady state pH between 3.2 - 3.7 for all technologies. Average DO readings were 2.9mg/L for conventional drainfield effluent and 4.6mg/L for advanced, showing the expected oxygen uptake with shallow placement of the infiltrative zone. The conventional OWTS is outperforming the advanced with respect to nitrogen removal, but renovating wastewater equivalently for all other contaminants of concern. The results of this study are expected to facilitate development of future OWTS regulation and planning guidelines, particularly in coastal zones and in the face of a changing climate.

  20. Quality of life among advanced breast cancer patients with and without distant metastasis.

    PubMed

    Wyatt, G; Sikorskii, A; Tamkus, D; You, M

    2013-03-01

    This study presents the results of a secondary analysis of data collected during a trial of reflexology that aimed to improve health-related quality of life (HRQOL) among women with advanced breast cancer in treatment. A comparison of HRQOL (functioning, symptoms, spirituality) of those with (n = 298) and without (n = 87) distant metastasis is presented. Following the intake interview, 385 women were randomised to reflexology, lay foot manipulation or conventional care control, and were interviewed again at weeks 5 and 11. Those with distant metastasis were older, had fewer comorbid conditions, and a smaller proportion were employed. Longitudinal analysis of HRQOL at intake, 5 and 11 weeks revealed that those with distant metastasis had lower functioning and more pain; however, no differences were found on fatigue, nausea, shortness of breath, sleep quality, anxiety, depressive symptoms or spirituality. Despite advanced disease, 56% of all women in this study were below the clinical screening cut-off for depressive symptoms. These findings may indicate that patients with advanced breast cancer have adapted emotionally and spiritually; however, the management of physical symptoms remains a priority. PMID:23252474

  1. Flight evaluation of advanced control systems and displays on a general aviation airplane

    NASA Technical Reports Server (NTRS)

    Loschke, P. C.; Barber, M. R.; Enevoldson, E. K.; Mcmurtry, T. C.

    1974-01-01

    A flight-test program was conducted to determine the effect of advanced flight control systems and displays on the handling qualities of a light twin-engined airplane. A flight-director display and an attitude-command control system, used separately and in combination, transformed a vehicle with poor handling qualities during ILS approaches in turbulent air into a vehicle with good handling qualities. The attitude-command control system also improved the ride qualities of the airplane. A rate-command control system made only small improvements to the airplane's ILS handling qualities in turbulence. Both the rate- and the attitude-command control systems reduced stall warning in the test airplane, increasing the likelihood of inadvertent stalls. The final approach to the point of flare was improved by both the rate- and the attitude-command control systems. However, the small control wheel deflections necessary to flare were unnatural and tended to cause overcontrolling during flare. Airplane handling qualities are summarized for each control-system and display configuration.

  2. 7 CFR 58.141 - Alternate quality control program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  3. 7 CFR 58.141 - Alternate quality control program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  4. Control of Smart Building Using Advanced SCADA

    NASA Astrophysics Data System (ADS)

    Samuel, Vivin Thomas

    For complete control of the building, a proper SCADA implementation and the optimization strategy has to be build. For better communication and efficiency a proper channel between the Communication protocol and SCADA has to be designed. This paper concentrate mainly between the communication protocol, and the SCADA implementation, for a better optimization and energy savings is derived to large scale industrial buildings. The communication channel used in order to completely control the building remotely from a distant place. For an efficient result we consider the temperature values and the power ratings of the equipment so that while controlling the equipment, we are setting a threshold values for FDD technique implementation. Building management system became a vital source for any building to maintain it and for safety purpose. Smart buildings, refers to various distinct features, where the complete automation system, office building controls, data center controls. ELC's are used to communicate the load values of the building to the remote server from a far location with the help of an Ethernet communication channel. Based on the demand fluctuation and the peak voltage, the loads operate differently increasing the consumption rate thus results in the increase in the annual consumption bill. In modern days, saving energy and reducing the consumption bill is most essential for any building for a better and long operation. The equipment - monitored regularly and optimization strategy is implemented for cost reduction automation system. Thus results in the reduction of annual cost reduction and load lifetime increase.

  5. Advanced mobile networking, sensing, and controls.

    SciTech Connect

    Feddema, John Todd; Kilman, Dominique Marie; Byrne, Raymond Harry; Young, Joseph G.; Lewis, Christopher L.; Van Leeuwen, Brian P.; Robinett, Rush D. III; Harrington, John J.

    2005-03-01

    This report describes an integrated approach for designing communication, sensing, and control systems for mobile distributed systems. Graph theoretic methods are used to analyze the input/output reachability and structural controllability and observability of a decentralized system. Embedded in each network node, this analysis will automatically reconfigure an ad hoc communication network for the sensing and control task at hand. The graph analysis can also be used to create the optimal communication flow control based upon the spatial distribution of the network nodes. Edge coloring algorithms tell us that the minimum number of time slots in a planar network is equal to either the maximum number of adjacent nodes (or degree) of the undirected graph plus some small number. Therefore, the more spread out that the nodes are, the fewer number of time slots are needed for communication, and the smaller the latency between nodes. In a coupled system, this results in a more responsive sensor network and control system. Network protocols are developed to propagate this information, and distributed algorithms are developed to automatically adjust the number of time slots available for communication. These protocols and algorithms must be extremely efficient and only updated as network nodes move. In addition, queuing theory is used to analyze the delay characteristics of Carrier Sense Multiple Access (CSMA) networks. This report documents the analysis, simulation, and implementation of these algorithms performed under this Laboratory Directed Research and Development (LDRD) effort.

  6. Applications of flight control system methods to an advanced combat rotorcraft

    NASA Technical Reports Server (NTRS)

    Tischler, Mark B.; Fletcher, Jay W.; Morris, Patrick M.; Tucker, George T.

    1989-01-01

    Advanced flight control system design, analysis, and testing methodologies developed at the Ames Research Center are applied in an analytical and flight test evaluation of the Advanced Digital Optical Control System (ADOCS) demonstrator. The primary objectives are to describe the knowledge gained about the implications of digital flight control system design for rotorcraft, and to illustrate the analysis of the resulting handling-qualities in the context of the proposed new handling-qualities specification for rotorcraft. Topics covered in-depth are digital flight control design and analysis methods, flight testing techniques, ADOCS handling-qualities evaluation results, and correlation of flight test results with analytical models and the proposed handling-qualities specification. The evaluation of the ADOCS demonstrator indicates desirable response characteristics based on equivalent damping and frequency, but undersirably large effective time-delays (exceeding 240 m sec in all axes). Piloted handling-qualities are found to be desirable or adequate for all low, medium, and high pilot gain tasks; but handling-qualities are inadequate for ultra-high gain tasks such as slope and running landings.

  7. Quality Control, Quality Assurance, and Quality Improvement-What is the Difference and Why Should Compounding Pharmacies Care?

    PubMed

    Cabaleiro, Joe

    2009-01-01

    This article provides scenarios of three different pharmacies in the areas of quality control, quality assurance, and quality improvement. The scenarios show the importance that each pharmacy placed on a problem of dented capsules and the potential impact that an unresolved problem can have on a compounding pharmacy's business. Although this article focuses on one particular procedure, the purpose of th article is to help pharmacists understand the differences between quality control, quality assurance, and quality improvement. PMID:23966522

  8. Quality Nursing Care for Hospitalized Patients with Advanced Illness: Concept Development

    PubMed Central

    Izumi, Shigeko; Baggs, Judith G.; Knafl, Kathleen A.

    2011-01-01

    The quality of nursing care as perceived by hospitalized patients with advanced illness has not been examined. A concept of quality nursing care for this population was developed by integrating the literature on constructs defining quality nursing care with empirical findings from interviews of 16 patients with advanced illness. Quality nursing care was characterized as competence and personal caring supported by professionalism and delivered with an appropriate demeanor. Although the attributes of competence, caring, professionalism, and demeanor were identified as common components of quality care across various patient populations, the caring domain increased in importance when patients with advanced illness perceived themselves as vulnerable. Assessment of quality nursing care for patients with advanced illness needs to include measures of patient perceptions of vulnerability. PMID:20572095

  9. Integration of cellular bioenergetics with mitochondrial quality control and autophagy

    PubMed Central

    Hill, Bradford G.; Benavides, Gloria A.; Lancaster, Jack R.; Ballinger, Scott; Dell’Italia, Lou; Zhang, Jianhua; Darley-Usmar, Victor M.

    2013-01-01

    Bioenergetic dysfunction is emerging as a cornerstone for establishing a framework for understanding the pathophysiology of cardiovascular disease, diabetes, cancer and neurodegeneration. Recent advances in cellular bioenergetics have shown that many cells maintain a substantial bioenergetic reserve capacity, which is a prospective index of “healthy” mitochondrial populations. The bioenergetics of the cell are likely regulated by energy requirements and substrate availability. Additionally, the overall quality of the mitochondrial population and the relative abundance of mitochondria in cells and tissues also impinge on overall bioenergetic capacity and resistance to stress. Because mitochondria are susceptible to damage mediated by reactive oxygen/nitrogen and lipid species, maintaining a “healthy” population of mitochondria through quality control mechanisms appears to be essential for cell survival under conditions of pathological stress. Accumulating evidence suggest that mitophagy is particularly important for preventing amplification of initial oxidative insults, which otherwise would further impair the respiratory chain or promote mutations in mitochondrial DNA (mtDNA). The processes underlying the regulation of mitophagy depend on several factors including the integrity of mtDNA, electron transport chain activity, and the interaction and regulation of the autophagic machinery. The integration and interpretation of cellular bioenergetics in the context of mitochondrial quality control and genetics is the theme of this review. PMID:23092819

  10. Human factors survey of advanced instrumentation and controls

    SciTech Connect

    Carter, R.J.

    1989-01-01

    A survey oriented towards identifying the human factors issues in regard to the use of advanced instrumentation and controls (I C) in the nuclear industry was conducted. A number of United States (US) and Canadian nuclear vendors and utilities were participants in the survey. Human factors items, subsumed under the categories of computer-generated displays (CGD), controls, organizational support, training, and related topics, were discussed. The survey found the industry to be concerned about the human factors issues related to the implementation of advanced I C. Fifteen potential human factors problems were identified. They include: the need for an advanced I C guideline equivalent to NUREG-0700; a role change in the control room from operator to supervisor; information overload; adequacy of existing training technology for advanced I C; and operator acceptance and trust. 11 refs., 1 tab.

  11. Data quality control of ADSN Broadband stations

    NASA Astrophysics Data System (ADS)

    Alili, Azouaou; Yelles-chaouche, Abd el karim; Allili, Toufik; Messemen, Walid

    2014-05-01

    In this work we present the analysis of continuous waveform of the Algerian digital seismic network recorded during five years from 2008 to 2013 for twenty broadband stations using the power spectral densities (PSDs) and their corresponding probability density functions (PDFs) algorithm of McNamara, and Buland (2004). ADSN Broadband stations data quality is one main concern and interest of ADSN technical team. Indeed, the quality of the data from broadband stations is continuously controlled in quasi-realtime using "PQLX" (Pascal Quick Look eXtended) software to compute the PDFs and PSDs during the operation of the stations at different frequency range. At each station the level of noise is shown, which we can see diurnal and seasonal variation. From the data analysis, most of the ADSN Broadband stations display good records in the several frequency domains in relation with their site installation. However some of stations near the urban areas could present some noisy disturbances. This led sometimes to generate some ghost events. In the low frequency, some stations could be still influenced by the temperature variations. This long period of records from 2008 to 2013, led us to analyze and control the several stations year by year taking into account the seasons and to know about their work during five years. This analysis is also very important to improve in the future quality of station installation and choose the optimal station design in aim to reduce cultural noise and large fluctuation of temperature and pressure. Key words: PQLX, PDFs, PSDs, Broad Band

  12. Advanced telerobotic control using neural networks

    NASA Technical Reports Server (NTRS)

    Pap, Robert M.; Atkins, Mark; Cox, Chadwick; Glover, Charles; Kissel, Ralph; Saeks, Richard

    1993-01-01

    Accurate Automation is designing and developing adaptive decentralized joint controllers using neural networks. We are then implementing these in hardware for the Marshall Space Flight Center PFMA as well as to be usable for the Remote Manipulator System (RMS) robot arm. Our design is being realized in hardware after completion of the software simulation. This is implemented using a Functional-Link neural network.

  13. Advancing a Technology of Self-Control.

    ERIC Educational Resources Information Center

    Martin, James E.; Mithaug, Dennis

    1986-01-01

    Examines self-control interventions considered effective in improving the performance of mentally retarded persons in acquiring, maintaining, and generalizing learned tasks. Studies employing self-monitoring, self-reinforcement, and antecedent cue regulation (self-instruction and picture cues) are cited. Picture cues are recommended as the most…

  14. Elements of an advanced integrated operator control station

    SciTech Connect

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of peformance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays, etc.) and the human operator. In the Remote Control Engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures.

  15. Elements of an advanced integrated operator control station

    SciTech Connect

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of performance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays) and the human operator. In the remote control engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures.

  16. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  17. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  18. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  19. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  20. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  1. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  2. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  3. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  4. EPANET - AN ADVANCED WATER QUALITY MODELING PACKAGE FOR DISTRIBUTION SYSTEMS

    EPA Science Inventory

    EPANET is a third generation software package for modeling water quality within drinking water distribution systems. he program performs extended period simulation of hydraulic and water quality conditions within pressurized pipe networks. n addition to substance concentration wa...

  5. Advanced concepts for controlling energy surety microgrids.

    SciTech Connect

    Menicucci, David F.; Ortiz-Moyet, Juan

    2011-05-01

    Today, researchers, engineers, and policy makers are seeking ways to meet the world's growing demand for energy while addressing critical issues such as energy security, reliability, and sustainability. Many believe that distributed generators operating within a microgrid have the potential to address most of these issues. Sandia National Laboratories has developed a concept called energy surety in which five of these 'surety elements' are simultaneously considered: energy security, reliability, sustainability, safety, and cost-effectiveness. The surety methodology leads to a new microgrid design that we call an energy surety microgrid (ESM). This paper discusses the unique control requirement needed to produce a microgrid system that has high levels of surety, describes the control system from the most fundamental level through a real-world example, and discusses our ideas and concepts for a complete system.

  6. Selected advanced aerodynamic and active control concepts development

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A task for the Energy Efficient Transport program conducted: (1) The design and wind tunnel development of high-aspect-ratio supercritical wings, investigating the cruise speed regime and also high-lift. (2) The preliminary design and evaluation of an aircraft combining a high-aspect-ratio supercritical wing with a winglet. (3) Active Controls: The determination of criteria, configuration, and flying qualities associated with augmented longitudinal stability of a level likely to be acceptable for the next generation transport; and the design of a practical augmentation system. The baseline against which the work was performed and evaluated was the Douglas DC-X-200 twin engine derivative of the DC-10 transport. The supercritical wing development showed that the cruise and buffet requirements could be achieved and that the wing could be designed to realize a sizable advantage over today's technology. Important advances in high lift performance were shown. The design study of an aircraft with supercritical wing and winglet suggested advantages in weight and fuel economy could be realized. The study of augmented stability, conducted with the aid of a motion base simulator, concluded that a negative static margin was acceptable for the baseline unaugmented aircraft.

  7. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control... PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality control requirements. (a) Continuous emission monitoring systems. The owner...

  8. Advanced CIDI Emission Control System Development

    SciTech Connect

    Lambert, Christine

    2006-05-31

    Ford Motor Company, with ExxonMobil and FEV, participated in the Department of Energy's (DOE) Ultra-Clean Transportation Fuels Program with the goal to develop an innovative emission control system for light-duty diesel vehicles. The focus on diesel engine emissions was a direct result of the improved volumetric fuel economy (up to 50%) and lower CO2 emissions (up to 25%) over comparable gasoline engines shown in Europe. Selective Catalytic Reduction (SCR) with aqueous urea as the NOx reductant and a Catalyzed Diesel Particulate Filter (CDPF) were chosen as the primary emission control system components. The program expected to demonstrate more than 90% durable reduction in particulate matter (PM) and NOx emissions on a light-duty truck application, based on the FTP-75 drive cycle. Very low sulfur diesel fuel (<15 ppm-wt) enabled lower PM emissions, reduced fuel economy penalty due to the emission control system and improved long-term system durability. Significant progress was made toward a durable system to meet Tier 2 Bin 5 emission standards on a 6000 lbs light-duty truck. A 40% reduction in engine-out NOx emissions was achieved with a mid-size prototype diesel engine through engine recalibration and increased exhaust gas recirculation. Use of a rapid warm-up strategy and urea SCR provided over 90% further NOx reduction while the CDPF reduced tailpipe PM to gasoline vehicle levels. Development work was conducted to separately improve urea SCR and CDPF system durability, as well as improved oxidation catalyst function. Exhaust gas NOx and ammonia sensors were also developed further. While the final emission control system did not meet Tier 2 Bin 5 NOx after 120k mi of aging on the dynamometer, it did meet the standards for HC, NMOG, and PM, and an improved SCR catalyst was shown to have potential to meet the NOx standard, assuming the DOC durability could be improved further. Models of DOC and SCR function were developed to guide the study of several key design

  9. Selected advanced aerodynamic and active control concepts development

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A summary is presented of results obtained during analysis, design and test activities on six selected technical tasks directed at exploratory improvement of fuel efficiency for new and derivative transports. The work included investigations into the potential offered by natural laminar flow, improved surface coatings and advanced high lift concepts. Similar investigations covering optimum low-energy flight path control, integrated application of active controls and evaluation of primary flight control systems reliability and maintenance are also summarized. Recommendations are included for future work needed to exploit potential advancements.

  10. Sensors, controls, and man-machine interface for advanced teleoperation

    NASA Technical Reports Server (NTRS)

    Bejczy, A. K.

    1980-01-01

    Some advances are reviewed which have been made in teleoperator (i.e., mechanical activities performed by mechanical devices at a remote site under remote control) technology through introduction of sensors, computers, automation, and new man-machine interface devices and techniques for remote manipulator control. The state of the art is summarized and some basic problems and challenging developments are examined.

  11. [Evaluating an internal quality control procedure: application to multidimensional control].

    PubMed

    Marquis, P; Masseyeff, R

    2002-01-01

    Internal quality control keeps in constant evolution in the industrial world. Introducing in clinical chemistry new QC methods derived from the industrial practice raises the point of the means for their evaluation. The main evaluation criteria are discussed in this paper. The importance of ARL (average run length) as a key-criterion of the efficiency of a quality control procedure is stressed. These principles were applied to the multivariate approach of multilevel control with the Hotelling's T2. This method led to a better detection of random errors than the independently managed conventional Shewhart (Levey- Jennings) charts. Applied to systematic errors, both methods gave similar results with a certain lack of sensitivity. However the multivariate method can be sensitised using EWMA (exponentially weighted moving average), a method specific for improved bias detection. EWMA efficiency outperforms that of the older systems of rules. Moreover, in any kind of error, multivariate approach secures a well-defined false rejection rate, whereas this rate is dependant on unknown inter-level correlation coefficients in conventional QC. PMID:12368148

  12. Advanced Integrated Power and Attitude Control System (IPACS) study

    NASA Technical Reports Server (NTRS)

    Oglevie, R. E.; Eisenhaure, D. B.

    1985-01-01

    Integrated Power and Attitude Control System (IPACS) studies performed over a decade ago established the feasibility of simultaneously satisfying the demands of energy storage and attitude control through the use of rotating flywheels. It was demonstrated that, for a wide spectrum of applications, such a system possessed many advantages over contemporary energy storage and attitude control approaches. More recent technology advances in composite material rotors, magnetic suspension systems, and power control electronics have triggered new optimism regarding the applicability and merits of this concept. This study is undertaken to define an advanced IPACS and to evaluate its merits for a space station application. System and component designs are developed to establish the performance of this concept and system trade studies conducted to examine the viability of this approach relative to conventional candidate systems. It is clearly demonstrated that an advanced IPACS concept is not only feasible, but also offers substantial savings in mass and life-cycle cost for the space station mission.

  13. Photonics in advanced process control applications

    NASA Astrophysics Data System (ADS)

    Lundqvist, Stefan H.; Andersson, Torbjoern; Grimbrandt, Jan

    1999-02-01

    A measurement system optimized for process control in the industrial environment has been developed and successfully commercialized. The system comprises a central unit, which contains all sensitive electronic and electro-optic parts. Fiber optics is used to transport the probing laser light to the measuring points in the process. Extremely rugged sensor heads are used to interface to the harsh industrial environment. Adaptation to the different applications is solely made up by changing the type of sensor head used. Six different process control applications will be presented. Ammonia slip monitoring in the NO(subscript x4/ reduction process in power stations, waste incinerators and heavy-duty diesel engines. Measurement of water vapor and oxygen in municipal waste to energy plants. Monitoring of oxygen and the thermodynamic gas temperature in steel pellets manufacturing. Monitoring HF reduction in a dry scrubber and HF emission from a pot room. Experiences of CO emission peak monitoring to protect electro filter in a chemical waste incinerator. Finally, we will describe measurements of HCI in the raw gas to access the calorific value of waste and to optimize bag-house filter operation.

  14. Advanced Control Methodology for Biomass Combustion

    NASA Astrophysics Data System (ADS)

    Bjornsson, Stefan

    This thesis presents a feasibility study for a low cost sensor-based combustion control system using a predictive chemical kinetic model that captures efficiencies and pollution emissions during biomass combustion. Low cost sensor module was developed, the sensors were calibrated to measure carbon monoxide and particulate matter (PM) in combustion exhaust. Major combustion species in the exhaust of a commercial biomass furnace, operating with white oak, were measured. The species concentrations were measured using the low cost sensors and commercially available diagnostics. The low cost sensor outputs compare well with the reference instruments and the sensors can be employed to measure varying concentration of CO and particulate matter in combustion exhaust. A predictive chemical kinetic model was generated to simulate biomass processes. The model uses a four element chemical reactor network (CRN) and successfully simulates smoldering, ignition and flaming combustion events. The model agrees with concentration of CO and particulate matter from experiments. The sensors and CRN model can be integrated in a control system for biomass combustion that can potentially improve combustion efficiency and reduce emissions of particulate matter, CO and unburned hydrocarbons that have been linked to urban and rural air pollution resulting in adverse health effects.

  15. Intelligent process quality control system into supply chain

    NASA Astrophysics Data System (ADS)

    Wang, Shijie; Jiang, Xingyu; Wang, Yingchun

    2010-01-01

    To cope with the challenges of monitoring dynamic and variable quality variation into supply chain, diagnosing the abnormal variation at the right moment, is a difficult problem that a enterprise in supply chain faces in process quality control. An intelligent process quality control mode into supply chain, which integrated quality prevention, analysis, diagnosis and adjustment, and corresponding functional modules and framework were all put forward. This mode dealt mainly with constructing and running intelligent quality control system, such as the theory of similarity manufacturing, Statistical Process Control (SPC), neural network. Furthermore, some key enabling technologies were studied in detail, including process quality analysis on-line based on similarity process and process quality diagnosis based on Elman and expert system of process quality adjustment. It is basis of realizing network, intelligent and automatic process quality control into supply.

  16. Intelligent process quality control system into supply chain

    NASA Astrophysics Data System (ADS)

    Wang, Shijie; Jiang, Xingyu; Wang, Yingchun

    2009-12-01

    To cope with the challenges of monitoring dynamic and variable quality variation into supply chain, diagnosing the abnormal variation at the right moment, is a difficult problem that a enterprise in supply chain faces in process quality control. An intelligent process quality control mode into supply chain, which integrated quality prevention, analysis, diagnosis and adjustment, and corresponding functional modules and framework were all put forward. This mode dealt mainly with constructing and running intelligent quality control system, such as the theory of similarity manufacturing, Statistical Process Control (SPC), neural network. Furthermore, some key enabling technologies were studied in detail, including process quality analysis on-line based on similarity process and process quality diagnosis based on Elman and expert system of process quality adjustment. It is basis of realizing network, intelligent and automatic process quality control into supply.

  17. Tools for quality control of fingerprint databases

    NASA Astrophysics Data System (ADS)

    Swann, B. Scott; Libert, John M.; Lepley, Margaret A.

    2010-04-01

    Integrity of fingerprint data is essential to biometric and forensic applications. Accordingly, the FBI's Criminal Justice Information Services (CJIS) Division has sponsored development of software tools to facilitate quality control functions relative to maintaining its fingerprint data assets inherent to the Integrated Automated Fingerprint Identification System (IAFIS) and Next Generation Identification (NGI). This paper provides an introduction of two such tools. The first FBI-sponsored tool was developed by the National Institute of Standards and Technology (NIST) and examines and detects the spectral signature of the ridge-flow structure characteristic of friction ridge skin. The Spectral Image Validation/Verification (SIVV) utility differentiates fingerprints from non-fingerprints, including blank frames or segmentation failures erroneously included in data; provides a "first look" at image quality; and can identify anomalies in sample rates of scanned images. The SIVV utility might detect errors in individual 10-print fingerprints inaccurately segmented from the flat, multi-finger image acquired by one of the automated collection systems increasing in availability and usage. In such cases, the lost fingerprint can be recovered by re-segmentation from the now compressed multi-finger image record. The second FBI-sponsored tool, CropCoeff was developed by MITRE and thoroughly tested via NIST. CropCoeff enables cropping of the replacement single print directly from the compressed data file, thus avoiding decompression and recompression of images that might degrade fingerprint features necessary for matching.

  18. mRNA quality control goes transcriptional

    PubMed Central

    Kilchert, Cornelia; Vasiljeva, Lidia

    2013-01-01

    Eukaryotic mRNAs are extensively processed to generate functional transcripts, which are 5′ capped, spliced and 3′ polyadenylated. Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms that identify erroneous transcripts and initiate their selective removal. Nucleases including Xrn2/Rat1 and the nuclear exosome have been shown to play an important role in the turnover of aberrant mRNAs. Recently, with the growing appreciation that mRNA processing occurs concomitantly with polII (RNA polymerase II) transcription, it has become evident that QC acts at the transcriptional level in addition to degrading aberrant RNAs. In the present review, we discuss mechanisms that allow cells to co-transcriptionally initiate the removal of RNAs as well as down-regulate transcription of transcripts where processing repeatedly fails. PMID:24256272

  19. Quality control in the "flash" process.

    PubMed

    1985-03-01

    This article has briefly discussed the three basic types of sterilization monitoring systems--mechanical, chemical, and biological. Mechanical indicators help tell you that the sterilizer is working. Chemical indicators provide you with immediate information in each "flash" load that the conditions necessary for steam sterilization were present. Biological indicators tell you that microorganisms were killed. For maximum assurance that the conditions necessary for steam sterilization are present and that non-sterile instruments are not inadvertently used, each "flash" sterilizer should be monitored daily with biological indicators and each "flash" load with chemical indicators. This quality control monitoring program should give the O.R. staff confidence that their "flash" sterilization process is working. PMID:10271096

  20. Advanced Controller for the Free-Piston Stirling Convertor

    NASA Technical Reports Server (NTRS)

    Gerber, Scott S.; Jamison, Mike; Roth, Mary Ellen; Regan, Timothy F.

    2004-01-01

    The free-piston Stirling power convertor is being considered as an advanced power conversion technology to be used for future NASA deep space missions requiring long life radioisotope power systems. This technology has a conversion efficiency of over 25%, which is significantly higher than the efficiency of the Radioisotope Thermal-electric Generators (RTG) now in use. The NASA Glenn Research Center has long been recognized as a leader in Stirling technology and is responsible for the development of advanced technologies that are intended to significantly improve key characteristics of the Stirling convertor. The advanced technologies identified for development also consider the requirements of potential future missions and the new capabilities that have become available in the associated technical areas. One of the key areas identified for technology development is the engine controller. To support this activity, an advanced controller is being developed for the Stirling power convertor. This controller utilizes active power factor correction electronics and microcontroller-based controls. The object of this paper is to present an overview of the advanced controller concept with modeling, simulation and hardware test data.

  1. Mitochondrial Quality Control as a Therapeutic Target.

    PubMed

    Suliman, Hagir B; Piantadosi, Claude A

    2016-01-01

    In addition to oxidative phosphorylation (OXPHOS), mitochondria perform other functions such as heme biosynthesis and oxygen sensing and mediate calcium homeostasis, cell growth, and cell death. They participate in cell communication and regulation of inflammation and are important considerations in aging, drug toxicity, and pathogenesis. The cell's capacity to maintain its mitochondria involves intramitochondrial processes, such as heme and protein turnover, and those involving entire organelles, such as fusion, fission, selective mitochondrial macroautophagy (mitophagy), and mitochondrial biogenesis. The integration of these processes exemplifies mitochondrial quality control (QC), which is also important in cellular disorders ranging from primary mitochondrial genetic diseases to those that involve mitochondria secondarily, such as neurodegenerative, cardiovascular, inflammatory, and metabolic syndromes. Consequently, mitochondrial biology represents a potentially useful, but relatively unexploited area of therapeutic innovation. In patients with genetic OXPHOS disorders, the largest group of inborn errors of metabolism, effective therapies, apart from symptomatic and nutritional measures, are largely lacking. Moreover, the genetic and biochemical heterogeneity of these states is remarkably similar to those of certain acquired diseases characterized by metabolic and oxidative stress and displaying wide variability. This biologic variability reflects cell-specific and repair processes that complicate rational pharmacological approaches to both primary and secondary mitochondrial disorders. However, emerging concepts of mitochondrial turnover and dynamics along with new mitochondrial disease models are providing opportunities to develop and evaluate mitochondrial QC-based therapies. The goals of such therapies extend beyond amelioration of energy insufficiency and tissue loss and entail cell repair, cell replacement, and the prevention of fibrosis. This review

  2. A formal structure for advanced automatic flight-control systems

    NASA Technical Reports Server (NTRS)

    Meyer, G.; Cicolani, L. S.

    1975-01-01

    Techniques were developed for the unified design of multimode, variable authority automatic flight-control systems for powered-lift STOL and VTOL aircraft. A structure for such systems is developed to deal with the strong nonlinearities inherent in this class of aircraft, to admit automatic coupling with advanced air traffic control, and to admit a variety of active control tasks. The aircraft being considered is the augmentor wing jet STOL research aircraft.

  3. ADVANCED COMPRESSOR ENGINE CONTROLS TO ENHANCE OPERATION, RELIABILITY AND INTEGRITY

    SciTech Connect

    Gary D. Bourn; Jess W. Gingrich; Jack A. Smith

    2004-03-01

    This document is the final report for the ''Advanced Compressor Engine Controls to Enhance Operation, Reliability, and Integrity'' project. SwRI conducted this project for DOE in conjunction with Cooper Compression, under DOE contract number DE-FC26-03NT41859. This report addresses an investigation of engine controls for integral compressor engines and the development of control strategies that implement closed-loop NOX emissions feedback.

  4. Controlling adsorbate interactions for advanced chemical patterning

    NASA Astrophysics Data System (ADS)

    Saavedra Garcia, Hector M.

    Molecules designed to have specific interactions were used to influence the structural, physical, and chemical properties of self-assembled monolayers. In the case of 1-adamantanethiolate monolayers, the molecular structure influences lability, enabling alkanethiol molecules in solution to displace the 1-adamantanethiolate monolayers, ultimately leading to complete molecular exchange. The similar Au-S bond environments measured for both n-alkanethiolate and 1-adamantanethiolate monolayers indicate that displacement is not a result of weakened Au-S bonds. Instead, it was hypothesized that the density differences in the two monolayers provide a substantial enthalpic driver, aided by differences in van der Waals forces, ultimately leading to complete displacement of the 1-adamantenthiol molecules. Additionally, it was discovered that displacement occurs via fast insertion of n-dodecanethiolate at the defects in the original 1-adamantanethiolate monolayer, which nucleates an island growth phase and is followed by slow ordering of the n-dodecanethiolate domains into a denser and more crystalline form. Langmuir-based kinetics, which describe alkanethiolate adsorption on bare Au{111}, fail to model this displacement reaction. Instead, a model of perimeter-dependent island growth yields good agreement with kinetic data over a 100-fold variation in n-dodecanethiol concentration. Rescaling the growth rate at each concentration collapses all the data onto a single universal curve, suggesting that displacement is a scale-free process. Exploiting the knowledge gained by studying 1-adamantethiolate monolayer displacement, a reversible molecular resist was developed, in which displacement is controlled via external stimuli. This methodology for the fabrication of controllably displaceable monolayers relies on carboxyl-functionalized self-assembled monolayers and in-situ Fischer esterification. Using an 11-mercaptoundecanoic acid monolayer as a model system, it was shown that in

  5. Quality control of antibodies for assay development.

    PubMed

    Schumacher, Sarah; Seitz, Harald

    2016-09-25

    Antibodies are used as powerful tools in basic research, for example, in biomarker identification, and in various forms for diagnostics, for example, identification of allergies or autoimmune diseases. Due to their robustness and ease of handling, immunoassays are favourite methods for investigation of various biological or medical questions. Nevertheless in many cases, additional analyses such as mass spectrometry are used to validate or confirm the results of immunoassays. To minimize the workload and to increase confidence in immunoassays, there are urgent needs for antibodies which are both highly specific and well validated. Unfortunately many commercially available antibodies are neither well characterized nor fully tested for cross-reactivities. Adequate quality control and validation of an antibody is time-consuming and can be frustrating. Such validation needs to be performed for every assay/application. However, where an antibody validation is successful, a highly specific and stable reagent will be on hand. This article describes the validation processes of antibodies, including some often neglected factors, as well as unspecific binding to other sample compounds in a multiparameter diagnostic assay. The validation consists of different immunological methods, with important assay controls, and is performed in relation to the development of a diagnostic test. PMID:26873787

  6. Machine Learning: Quality Control of HST Grism Spectra

    NASA Astrophysics Data System (ADS)

    Stoehr, F.; Walsh, J.; Kuntschner, H.; Rosati, P.; Fosbury, R.; Kümmel, M.; Haase, J.; Hook, R.; Lombardi, M.; Nilsson, K.; Rosa, M.

    2011-07-01

    The Pipeline for Hubble Legacy Archive Grism data (PHLAG) had been used to extract more than 70000 wavelength and flux calibrated 1D spectra. They were obtained from 153 fields observed in G800L grism spectroscopy mode with the Advanced Camera for Surveys on the Hubble Space Telescope. This number of spectra is far too large to allow detailed visual inspection for quality control on reasonable time-scales. As a solution, we use machine learning techniques to classify spectra into "good" and "bad" based on a careful visual inspection of only about 3% of the full sample. A final visual skim through the set of "good" spectra was made to remove catastrophic failures. The remaining 47919 spectra form the largest set of slitless high-level spectroscopic data products publicly released to date.

  7. How Quality Improvement Practice Evidence Can Advance the Knowledge Base.

    PubMed

    OʼRourke, Hannah M; Fraser, Kimberly D

    2016-01-01

    Recommendations for the evaluation of quality improvement interventions have been made in order to improve the evidence base of whether, to what extent, and why quality improvement interventions affect chosen outcomes. The purpose of this article is to articulate why these recommendations are appropriate to improve the rigor of quality improvement intervention evaluation as a research endeavor, but inappropriate for the purposes of everyday quality improvement practice. To support our claim, we describe the differences between quality improvement interventions that occur for the purpose of practice as compared to research. We then carefully consider how feasibility, ethics, and the aims of evaluation each impact how quality improvement interventions that occur in practice, as opposed to research, can or should be evaluated. Recommendations that fit the evaluative goals of practice-based quality improvement interventions are needed to support fair appraisal of the distinct evidence they produce. We describe a current debate on the nature of evidence to assist in reenvisioning how quality improvement evidence generated from practice might complement that generated from research, and contribute in a value-added way to the knowledge base. PMID:27584696

  8. Recent Advances in WRF Modeling for Air Quality Applications

    EPA Science Inventory

    The USEPA uses WRF in conjunction with the Community Multiscale Air Quality (CMAQ) for air quality regulation and research. Over the years we have added physics options and geophysical datasets to the WRF system to enhance model capabilities especially for extended retrospective...

  9. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for equipment, instruments, and controls? 111.117 Section 111.117 Food and Drugs FOOD AND DRUG ADMINISTRATION... and Process Control System: Requirements for Quality Control § 111.117 What quality control...

  10. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false What quality control operations are required for equipment, instruments, and controls? 111.117 Section 111.117 Food and Drugs FOOD AND DRUG ADMINISTRATION... and Process Control System: Requirements for Quality Control § 111.117 What quality control...

  11. Advanced robust tracking control of a powered wheelchair system.

    PubMed

    Nguyen, Nghia T; Nguyen, Hung T; Su, Steven

    2007-01-01

    In this paper, the dynamic multivariable model of the wheelchair system is obtained including the presence of transportation lags. The triangular diagonal dominance (TDD) decoupling technique is applied to reduce this multivariable control problem into two independent scalar control problems. An advanced robust control technique for the wheelchair has been developed based on the combination of a TDD decoupling strategy and neural network controller design. The results obtained from the real-time implementation confirm that robust performance for this multivariable wheelchair control system can indeed be achieved. PMID:18003071

  12. Multivariable quadratic synthesis of an advanced turbofan engine controller

    NASA Technical Reports Server (NTRS)

    Dehoff, R. L.; Hall, W. E., Jr.

    1978-01-01

    A digital controller for an advanced turbofan engine utilizing multivariate feedback is described. The theoretical background of locally linearized control synthesis is reviewed briefly. The application of linear quadratic regulator techniques to the practical control problem is presented. The design procedure has been applied to the F100 turbofan engine, and details of the structure of this system are explained. Selected results from simulations of the engine and controller are utilized to illustrate the operation of the system. It is shown that the general multivariable design procedure will produce practical and implementable controllers for modern, high-performance turbine engines.

  13. [Improvement of routine works and quality control in mycobacterial laboratory].

    PubMed

    Suzuki, Katsuhiro; Higuchi, Takeshi

    2007-03-01

    detected monthly in 2005 is up to 5 for isoniazid (INH), 4 for rifampicin (RFP), 7 for streptomycin (SM), 1 for ethambutol (EB), and 2 for pyrazinamide (PZA), respectively. If any serious deviation from the average number is observed, action for the investigation is taken. The analysis of the ordinary examination data is useful to implement a quality control efficiently, and to improve the total laboratory performance. 3. The advanced devices for solving problems of the smears and cultivation of Mycobacteria: Motohisa TOMITA (NHO Kinki-chuo Chest Medical Center). Recently, the newly developed, standardized, commercially available kits including PCR and liquid media for confirmation and identification of mycobacteria are prevalent in Japan for the rapid diagnosis of M. tuberculosis. These tests are sensitive and accurate, but still expensive and technically demanding. The improvement of these methods, in particular, requires time-consuming process. We have optimized the culture technique, the identification method, and the drug-susceptibility testing for Mycobacteria in a time-saving manner. They should provide a basic grounding in the application of the techniques for anyone who is interested in these intriguing bacteria. 4. Ultimate quality control of specimens--teaching how to get a good sputum sample: Takeshi HIGUCHI (Kyoto University Hospital). Modern techniques including molecular biology have been applied to routine laboratory works for rapid detection, identification, and drug susceptibility testing of mycobacteria. Even in using such techniques, however, poor quality specimens yield only poor results. To get a high quality specimen, particularly sputum samples, is very important. Therefore, laboratory technicians in our hospital have directly taught each patient how to expectorate good quality sputa since 2001. The teaching of patients has improved the rate of P1 samples from 21.5% to 36.6% by Miller and Jones visual score of sputum. The teaching has also improved

  14. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT...) Each quality control plan shall contain provisions for the management of quality, including: (1... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control plans; contents. 28.31...

  15. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT...) Each quality control plan shall contain provisions for the management of quality, including: (1... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; contents. 28.31...

  16. 75 FR 41874 - Quality Control for Rental Assistance Subsidy Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... URBAN DEVELOPMENT Quality Control for Rental Assistance Subsidy Determinations AGENCY: Office of the... agency's estimate of the burden of the proposed collection of information; (3) Enhance the quality.... This notice also lists the following information: Title of Proposal: Quality Control for...

  17. 14 CFR 21.147 - Changes in quality control system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality...

  18. 14 CFR 21.147 - Changes in quality control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality...

  19. Minimum Control Requirements for Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Boulange, Richard; Jones, Harry; Jones, Harry

    2002-01-01

    Advanced control technologies are not necessary for the safe, reliable and continuous operation of Advanced Life Support (ALS) systems. ALS systems can and are adequately controlled by simple, reliable, low-level methodologies and algorithms. The automation provided by advanced control technologies is claimed to decrease system mass and necessary crew time by reducing buffer size and minimizing crew involvement. In truth, these approaches increase control system complexity without clearly demonstrating an increase in reliability across the ALS system. Unless these systems are as reliable as the hardware they control, there is no savings to be had. A baseline ALS system is presented with the minimal control system required for its continuous safe reliable operation. This baseline control system uses simple algorithms and scheduling methodologies and relies on human intervention only in the event of failure of the redundant backup equipment. This ALS system architecture is designed for reliable operation, with minimal components and minimal control system complexity. The fundamental design precept followed is "If it isn't there, it can't fail".

  20. Advance Care Planning and the Quality of End-of-Life Care among Older Adults

    PubMed Central

    Bischoff, Kara E.; Sudore, Rebecca; Miao, Yinghui; Boscardin, W. John; Smith, Alexander K.

    2013-01-01

    Background Advance care planning is increasingly common, but whether it influences end-of-life quality of care remains controversial. Design Medicare data and survey data from the Health and Retirement Study were combined to determine whether advance care planning was associated with quality metrics. Setting The nationally representative Health and Retirement Study. Participants 4394 decedent subjects (mean age 82.6 years at death, 55% women). Measurements Advance care planning was defined as having an advance directive, durable power of attorney or having discussed preferences for end-of-life care with a next-of-kin. Outcomes included previously reported quality metrics observed during the last month of life (rates of hospital admission, in-hospital death, >14 days in the hospital, intensive care unit admission, >1 emergency department visit, hospice admission, and length of hospice ≤3 days). Results Seventy-six percent of subjects engaged in advance care planning. Ninety-two percent of advance directives stated a preference to prioritize comfort. After adjustment, subjects who engaged in advance care planning were less likely to die in a hospital (adjusted RR 0.87, 95% CI 0.80-0.94), more likely to be enrolled in hospice (aRR 1.68, 1.43-1.97), and less likely to receive hospice for ≤3 days before death (aRR 0.88, 0.85-0.91). Having an advance directive, a durable-power-of-attorney or an advance care planning discussion were each independently associated with a significant increase in hospice use (p<0.01 for all). Conclusion Advance care planning was associated with improved quality of care at the end of life, including less in-hospital death and increased use of hospice. Having an advance directive, assigning a durable power of attorney and conducting advance care planning discussions are all important elements of advance care planning. PMID:23350921

  1. A Control Law Design Method Facilitating Control Power, Robustness, Agility, and Flying Qualities Tradeoffs: CRAFT

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick C.; Davidson, John B.

    1998-01-01

    A multi-input, multi-output control law design methodology, named "CRAFT", is presented. CRAFT stands for the design objectives addressed, namely, Control power, Robustness, Agility, and Flying Qualities Tradeoffs. The methodology makes use of control law design metrics from each of the four design objective areas. It combines eigenspace assignment, which allows for direct specification of eigenvalues and eigenvectors, with a graphical approach for representing the metrics that captures numerous design goals in one composite illustration. Sensitivity of the metrics to eigenspace choice is clearly displayed, enabling the designer to assess the cost of design tradeoffs. This approach enhances the designer's ability to make informed design tradeoffs and to reach effective final designs. An example of the CRAFT methodology applied to an advanced experimental fighter and discussion of associated design issues are provided.

  2. REFINED PHOTOLYSIS RATES FOR ADVANCED AIR QUALITY MODELING SYSTEM

    EPA Science Inventory

    Accurate modeling of photochemistry is critical and fundamental to reducing the uncertainty in air quality model predictions. lmost all chemical reactions in the atmosphere are initiated by the photodissociation of a number of trace gases. irect measure of this photodissociation ...

  3. Application of Advanced Process Control techniques to a pusher type reheating furnace

    NASA Astrophysics Data System (ADS)

    Zanoli, S. M.; Pepe, C.; Barboni, L.

    2015-11-01

    In this paper an Advanced Process Control system aimed at controlling and optimizing a pusher type reheating furnace located in an Italian steel plant is proposed. The designed controller replaced the previous control system, based on PID controllers manually conducted by process operators. A two-layer Model Predictive Control architecture has been adopted that, exploiting a chemical, physical and economic modelling of the process, overcomes the limitations of plant operators’ mental model and knowledge. In addition, an ad hoc decoupling strategy has been implemented, allowing the selection of the manipulated variables to be used for the control of each single process variable. Finally, in order to improve the system flexibility and resilience, the controller has been equipped with a supervision module. A profitable trade-off between conflicting specifications, e.g. safety, quality and production constraints, energy saving and pollution impact, has been guaranteed. Simulation tests and real plant results demonstrated the soundness and the reliability of the proposed system.

  4. Comparison of Advanced Distillation Control Methods, Final Technical Report

    SciTech Connect

    Dr. James B. Riggs

    2000-11-30

    Detailed dynamic simulations of three industrial distillation columns (a propylene/propane splitter, a xylene/toluene column, and a depropanizer) have been used to evaluate configuration selections for single-ended and dual-composition control, as well as to compare conventional and advanced control approaches. In addition, a simulator of a main fractionator was used to compare the control performance of conventional and advanced control. For each case considered, the controllers were tuned by using setpoint changes and tested using feed composition upsets. Proportional Integral (PI) control performance was used to evaluate the configuration selection problem. For single ended control, the energy balance configuration was found to yield the best performance. For dual composition control, nine configurations were considered. It was determined that the use of dynamic simulations is required in order to identify the optimum configuration from among the nine possible choices. The optimum configurations were used to evaluate the relative control performance of conventional PI controllers, MPC (Model Predictive Control), PMBC (Process Model-Based Control), and ANN (Artificial Neural Networks) control. It was determined that MPC works best when one product is much more important than the other, while PI was superior when both products were equally important. PMBC and ANN were not found to offer significant advantages over PI and MPC. MPC was found to outperform conventional PI control for the main fractionator. MPC was applied to three industrial columns: one at Phillips Petroleum and two at Union Carbide. In each case, MPC was found to significantly outperform PI controls. The major advantage of the MPC controller is its ability to effectively handle a complex set of constraints and control objectives.

  5. Overview of the US program of controls for advanced reactors

    SciTech Connect

    White, J.D.; Sackett, J.I.; Monson, R.; Lindsay, R.W.; Carroll, D.G.

    1989-01-01

    An automated control system can incorporate control goals and strategies, assessment of present and future plant status, diagnostic evaluation and maintenance planning, and signal and command validation. It has not been feasible to employ these capabilities in conventional hard-wired, analog, control systems. Recent advances in computer-based digital data acquisition systems, process controllers, fiber-optic signal transmission artificial intelligence tools and methods, and small inexpensive, fast, large-capacity computers---with both numeric and symbolic capabilities---have provided many of the necessary ingredients for developing large, practical automated control systems. Furthermore, recent reactor designs which provide strong passive responses to operational upsets or accidents afford good opportunities to apply these advances in control technology. This paper presents an overall US national perspective for advanced controls research and development. The goals of high reliability, low operating cost and simple operation are described. The staged approach from conceptualization through implementation is discussed. Then the paper describes the work being done by ORNL, ANL and GE. The relationship of this work to the US commercial industry is also discussed.

  6. Vision Based Autonomous Robotic Control for Advanced Inspection and Repair

    NASA Technical Reports Server (NTRS)

    Wehner, Walter S.

    2014-01-01

    The advanced inspection system is an autonomous control and analysis system that improves the inspection and remediation operations for ground and surface systems. It uses optical imaging technology with intelligent computer vision algorithms to analyze physical features of the real-world environment to make decisions and learn from experience. The advanced inspection system plans to control a robotic manipulator arm, an unmanned ground vehicle and cameras remotely, automatically and autonomously. There are many computer vision, image processing and machine learning techniques available as open source for using vision as a sensory feedback in decision-making and autonomous robotic movement. My responsibilities for the advanced inspection system are to create a software architecture that integrates and provides a framework for all the different subsystem components; identify open-source algorithms and techniques; and integrate robot hardware.

  7. Quality assurance standards for purchasing and inventory control.

    PubMed

    Soares, D P

    1985-03-01

    A process is described for quality assurance in pharmaceutical purchasing and inventory control. A quality assurance program should ensure that quality drugs are purchased at the lowest price, drug products are available when needed, the system is managed efficiently, internal controls are provided, drug products are stored under appropriate conditions, and laws, regulations, accreditation standards, and procedures are followed. To meet these objectives, product quality, vendor performance, the department's system of internal controls, purchasing data, and storage conditions should be monitored. A checklist for evaluating purchasing and inventory practices and a sample audit form listing quality assurance criteria, standards, procedures, and recommended actions are provided. A quality assurance program for pharmaceutical purchasing and inventory control should define institution-specific criteria and standards and use these standards for continual evaluation of all aspects of the purchasing and inventory control system. Documentation of quality assurance activities should be provided for use by the purchasing department, hospital administration, and regulatory bodies. PMID:3985026

  8. Advanced software design and standards for traffic signal control

    SciTech Connect

    Bullock, D.; Hendrickson, C. )

    1992-05-01

    Improves traffic management and control systems are widely reported to be cost-effective investments. Simply retiming signals can provide significant benefits by reducing vehicle stops, travel times, and fuel consumption. The installation of advanced traffic management systems (ATMS) can provide even greater savings. However, many hardware and software obstacles have impeded the actual implementation of advanced traffic management systems. The general hardware and software limitations of current traffic signal control technology are reviewed in this paper. The impact of these deficiencies is discussed in the context of three example applications. Based on this discussion, the paper identifies several computing issues that should be addressed in order to reduce the effort involved with integrating existing traffic control devices. Adoption of standard industrial control computing platforms and development of new communication and software engineering models are recommendrecommended.

  9. ANALYSIS ON EFFLUENT WATER QUALITY AND ELECTRICITY CONSUMPTION AFTER INTRODUCING ADVANCED SEWAGE TREATMENT

    NASA Astrophysics Data System (ADS)

    Shiojiri, Yasuo; Maekawa, Shunich

    We analyze effluent water quality and electricity consumption after in troducing advanced treatment in sewage treatment plant. We define 'advanced treatment ratio' as volume of treated water through advanced treatment processes divided by total volume of treated water in plant. Advanced treatment ratio represents degree of introducing advanced treatment. We build two types of equation. One represents relation between effluent water quality and advanced treatment ratio, the other between electricity consumption and advanced treatment ratio. Each equation is fitted by least squares on 808 samples: 8 fiscal years operation data of 101 plants working in Kanagawa, Tokyo, Saitama and Chiba areas, and coefficient of advanced treatment ratio is estimated. The result is as follows. (1) After introducing advanced treatment aimed at nitrogen removal, T-N in effluent water decreases by 51.3% and electricity consum ption increases by 52.2%. (2) After introducing advanced treatment aimed at phosphorus removal, T-P in effluent water decreases by 27.8%. Using the above result, we try prioritizing 71 plants in Tokyo Bay watershed about raising advanced treatment ratio, so that, in total, pollutant in effluent water decreases with minimized increase of electricity consumption.

  10. Timing control improves seabed survey data quality

    SciTech Connect

    Green, R.

    1996-04-01

    Seateam has completed development of and field-proven the Dolphin data acquisition and timing system for high-density surveys offshore. The Dolphin project was initiated to improve quality control of survey sensor data and ensure time synchronization, thus leading to faster turnaround of seabed terrain information. Data received from survey sensors is asynchronous, so the system must provide for data correlation. This includes establishment of data latency, i.e., the time difference between data creation and timing of the message at first-byte arrival at the recording system. Until recently, asynchronous data from multiple sensors was collected by a single computer, regardless of whether it had additional intelligent or non-intelligent serial cards. This computer was fully responsible for time stamping all incoming data, plus associated storage and distribution. Though this initially sufficed and is still applicable to low-density data, increasingly larger data volumes required an associated boost in the capability to time stamp data prior to eventual correction.

  11. Mitochondrial Quality Control and Muscle Mass Maintenance

    PubMed Central

    Romanello, Vanina; Sandri, Marco

    2016-01-01

    Loss of muscle mass and force occurs in many diseases such as disuse/inactivity, diabetes, cancer, renal, and cardiac failure and in aging-sarcopenia. In these catabolic conditions the mitochondrial content, morphology and function are greatly affected. The changes of mitochondrial network influence the production of reactive oxygen species (ROS) that play an important role in muscle function. Moreover, dysfunctional mitochondria trigger catabolic signaling pathways which feed-forward to the nucleus to promote the activation of muscle atrophy. Exercise, on the other hand, improves mitochondrial function by activating mitochondrial biogenesis and mitophagy, possibly playing an important part in the beneficial effects of physical activity in several diseases. Optimized mitochondrial function is strictly maintained by the coordinated activation of different mitochondrial quality control pathways. In this review we outline the current knowledge linking mitochondria-dependent signaling pathways to muscle homeostasis in aging and disease and the resulting implications for the development of novel therapeutic approaches to prevent muscle loss. PMID:26793123

  12. Quality Control of Diffusion Weighted Images

    PubMed Central

    Liu, Zhexing; Wang, Yi; Gerig, Guido; Gouttard, Sylvain; Tao, Ran; Fletcher, Thomas; Styner, Martin

    2013-01-01

    Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple directional encoding with correspondingly large risk to encounter several kinds of artifacts. These artifacts can be too severe for a correct and stable estimation of the diffusion tensor. Thus, a quality control (QC) procedure is absolutely necessary for DTI studies. Currently, routine DTI QC procedures are conducted manually by visually checking the DWI data set in a gradient by gradient and slice by slice way. The results often suffer from low consistence across different data sets, lack of agreement of different experts, and difficulty to judge motion artifacts by qualitative inspection. Additionally considerable manpower is needed for this step due to the large number of images to QC, which is common for group comparison and longitudinal studies, especially with increasing number of diffusion gradient directions. We present a framework for automatic DWI QC. We developed a tool called DTIPrep which pipelines the QC steps with a detailed protocoling and reporting facility. And it is fully open source. This framework/tool has been successfully applied to several DTI studies with several hundred DWIs in our lab as well as collaborating labs in Utah and Iowa. In our studies, the tool provides a crucial piece for robust DTI analysis in brain white matter study. PMID:24353379

  13. Quality control and reliability of reported doses.

    PubMed

    Stadtmann, H; Figel, Markus; Kamenopoulou, V; Kluszczynski, D; Roed, H; Van Dijk, J

    2004-01-01

    Results of performance tests verifying the dosimetric properties of dosimetric systems are published in various reports (e.g. IAEA and EURADOS). However, there is hardly any information in the open literature relating to the uncertainty in a dose measurement or in the annual dose, which is increased by failure of the evaluation or data management system, damage of the dosemeter itself or by the loss of dosemeter. In this article, an attempt is made to estimate the importance of the above-mentioned conditions. This is achieved by sending questionnaires to about 200 approved dosimetric services in Europe. In total 88 questionnaires were returned and analysed. In the questionnaires, the frequency of occurrence of the various error conditions were investigated. Participants were also asked to evaluate the impact of the error condition from a dosimetric point of view and what countermeasures are taken. The article summarises all responses and compares different sources of errors according to their impact on the uncertainty of the resulting dose and gives a comprehensive overview on quality control actions and reliability on reported doses from European dosimetric services. PMID:15574990

  14. Toward standardising gamma camera quality control procedures

    NASA Astrophysics Data System (ADS)

    Alkhorayef, M. A.; Alnaaimi, M. A.; Alduaij, M. A.; Mohamed, M. O.; Ibahim, S. Y.; Alkandari, F. A.; Bradley, D. A.

    2015-11-01

    Attaining high standards of efficiency and reliability in the practice of nuclear medicine requires appropriate quality control (QC) programs. For instance, the regular evaluation and comparison of extrinsic and intrinsic flood-field uniformity enables the quick correction of many gamma camera problems. Whereas QC tests for uniformity are usually performed by exposing the gamma camera crystal to a uniform flux of gamma radiation from a source of known activity, such protocols can vary significantly. Thus, there is a need for optimization and standardization, in part to allow direct comparison between gamma cameras from different vendors. In the present study, intrinsic uniformity was examined as a function of source distance, source activity, source volume and number of counts. The extrinsic uniformity and spatial resolution were also examined. Proper standard QC procedures need to be implemented because of the continual development of nuclear medicine imaging technology and the rapid expansion and increasing complexity of hybrid imaging system data. The present work seeks to promote a set of standard testing procedures to contribute to the delivery of safe and effective nuclear medicine services.

  15. Optical metrology for advanced process control: full module metrology solutions

    NASA Astrophysics Data System (ADS)

    Bozdog, Cornel; Turovets, Igor

    2016-03-01

    Optical metrology is the workhorse metrology in manufacturing and key enabler to patterning process control. Recent advances in device architecture are gradually shifting the need for process control from the lithography module to other patterning processes (etch, trim, clean, LER/LWR treatments, etc..). Complex multi-patterning integration solutions, where the final pattern is the result of multiple process steps require a step-by-step holistic process control and a uniformly accurate holistic metrology solution for pattern transfer for the entire module. For effective process control, more process "knobs" are needed, and a tighter integration of metrology with process architecture.

  16. Status report on the Advanced Light Source control system, 1993

    SciTech Connect

    Young, J.; Brown, W. Jr.; Cork, C.

    1993-10-01

    The Advanced Light Source (ALS), under construction for the past seven years, has become operational. The accelerator has been successfully commissioned using a control system based on hundreds of controllers of our own design and high performance personal computers which are the operator interface. The first beamlines are being commissioned using a control system based on VME hardware and the Experimental Physics and Industrial Control System (EPICS) software. The two systems are being integrated, and this paper reports on the current work being done.

  17. Advanced reactor instrumentation and control reliability and risk assessment

    SciTech Connect

    Fullwood, R.; Gunther, W.; Valente, J.; Azarm, M.A.

    1991-01-01

    Advanced nuclear power reactors will used different approaches to achieving a higher level of safety than the first generation. One approach used the technological developments in computation and electronics in the form of digital instrumentation and control (I C) to enhance the reliability, and accuracy of information for plant control, responding to the information, and controlling the plant and its systems under normal and upset environments in various states of degradation. Evaluating the reliability and safety of advanced I C systems requires determining the reliability of the I C used in the advanced reactors which involves distributed processing, data pile-up, interactive systems, the man-machine interface, various forms of automatic control, and systems interactions. From these analyses will come an understanding of the potential of the new I C, and protection from its vulnerabilities to enhance the safe operation of the new plants. Technological, safety, reliability, and regulatory issues associated with advanced I C for the new reactors are discussed herein. The issues are presented followed by suggested approaches to their resolution.

  18. Advanced reactor instrumentation and control reliability and risk assessment

    SciTech Connect

    Fullwood, R.; Gunther, W.; Valente, J.; Azarm, M.A.

    1991-12-31

    Advanced nuclear power reactors will used different approaches to achieving a higher level of safety than the first generation. One approach used the technological developments in computation and electronics in the form of digital instrumentation and control (I&C) to enhance the reliability, and accuracy of information for plant control, responding to the information, and controlling the plant and its systems under normal and upset environments in various states of degradation. Evaluating the reliability and safety of advanced I&C systems requires determining the reliability of the I&C used in the advanced reactors which involves distributed processing, data pile-up, interactive systems, the man-machine interface, various forms of automatic control, and systems interactions. From these analyses will come an understanding of the potential of the new I&C, and protection from its vulnerabilities to enhance the safe operation of the new plants. Technological, safety, reliability, and regulatory issues associated with advanced I&C for the new reactors are discussed herein. The issues are presented followed by suggested approaches to their resolution.

  19. Advanced control for airbreathing engines, volume 1: Pratt and Whitney

    NASA Technical Reports Server (NTRS)

    Ralph, J. A.

    1993-01-01

    The application of advanced control concepts to air breathing engines may yield significant improvements in aircraft/engine performance and operability. Screening studies of advanced control concepts for air breathing engines were conducted by three major domestic aircraft engine manufacturers to determine the potential impact of concepts on turbine engine performance and operability. The purpose of the studies was to identify concepts which offered high potential yet may incur high research and development risk. A target suite of proposed advanced control concepts was formulated and evaluated in a two phase study to quantify each concept's impact on desired engine characteristics. To aid in the evaluation specific aircraft/engine combinations were considered: a Military High Performance Fighter mission, a High Speed Civil Transport mission, and a Civil Tiltrotor mission. Each of the advanced control concepts considered in the study are defined and described. The concept potential impact on engine performance was determined. Relevant figures of merit on which to evaluate the concepts are determined. Finally, the concepts are ranked with respect to the target aircraft/engine missions. A final report describing the screening studies was prepared by each engine manufacturer. Volume 1 of these reports describes the studies performed by Pratt & Whitney.

  20. Advanced controls for airbreathing engines, volume 3: Allison gas turbine

    NASA Technical Reports Server (NTRS)

    Bough, R. M.

    1993-01-01

    The application of advanced control concepts to airbreathing engines may yield significant improvements in aircraft/engine performance and operability. Screening studies of advanced control concepts for airbreathing engines were conducted by three major domestic aircraft engine manufacturers to determine the potential impact of concepts on turbine engine performance and operability. The purpose of the studies was to identify concepts which offered high potential yet may incur high research and development risk. A target suite of proposed advanced control concepts was formulated and evaluated in a two-phase study to quantify each concept's impact on desired engine characteristics. To aid in the evaluation specific aircraft/engine combinations were considered: a Military High Performance Fighter mission, a High Speed Civil Transport mission, and a Civil Tiltrotor mission. Each of the advanced control concepts considered in the study are defined and described. The concept potential impact on engine performance was determined. Relevant figures of merit on which to evaluate the concepts are determined. Finally, the concepts are ranked with respect to the target aircraft/engine missions. A final report describing the screening studies was prepared by each engine manufacturer. Volume 3 of these reports describes the studies performed by the Allison Gas Turbine Division.

  1. The implementation and control of advanced manufacturing systems

    NASA Astrophysics Data System (ADS)

    Anstiss, P.

    An account is given of the development and control of a flexible manufacturing system for small machined parts which can prepare raw materials for fixturing, assemble all necessary resources, then process 'nests' of components through machining, inspection, and secondary operations to produce finished parts ready for surface treatment or painting. The system employs automated stores, transport and machine tools, local area network communications, advanced computer control systems for all automatic and manual functions, and comprehensive tool storage, handling and preparation facilities.

  2. Access control and interlock system at the Advanced Photon Source

    SciTech Connect

    Forrestal, J.; Hogrefe, R.; Knott, M.; McDowell, W.; Reigle, D.; Solita, L.; Koldenhoven, R.; Haid, D.

    1997-08-01

    The Advanced Photon Source (APS) consists of a linac, position accumulator ring (PAR), booster synchrotron, storage ring, and up to 70 experimental beamlines. The Access Control and Interlock System (ACIS) utilizes redundant programmable logic controllers (PLCs) and a third hard-wired chain to protect personnel from prompt radiation generated by the linac, PAR, synchrotron, and storage ring. This paper describes the ACIS`s design philosophy, configuration, hardware, functionality, validation requirements, and operational experience.

  3. Supervisory Control System Architecture for Advanced Small Modular Reactors

    SciTech Connect

    Cetiner, Sacit M; Cole, Daniel L; Fugate, David L; Kisner, Roger A; Melin, Alexander M; Muhlheim, Michael David; Rao, Nageswara S; Wood, Richard Thomas

    2013-08-01

    This technical report was generated as a product of the Supervisory Control for Multi-Modular SMR Plants project within the Instrumentation, Control and Human-Machine Interface technology area under the Advanced Small Modular Reactor (SMR) Research and Development Program of the U.S. Department of Energy. The report documents the definition of strategies, functional elements, and the structural architecture of a supervisory control system for multi-modular advanced SMR (AdvSMR) plants. This research activity advances the state-of-the art by incorporating decision making into the supervisory control system architectural layers through the introduction of a tiered-plant system approach. The report provides a brief history of hierarchical functional architectures and the current state-of-the-art, describes a reference AdvSMR to show the dependencies between systems, presents a hierarchical structure for supervisory control, indicates the importance of understanding trip setpoints, applies a new theoretic approach for comparing architectures, identifies cyber security controls that should be addressed early in system design, and describes ongoing work to develop system requirements and hardware/software configurations.

  4. Quality metric for accurate overlay control in <20nm nodes

    NASA Astrophysics Data System (ADS)

    Klein, Dana; Amit, Eran; Cohen, Guy; Amir, Nuriel; Har-Zvi, Michael; Huang, Chin-Chou Kevin; Karur-Shanmugam, Ramkumar; Pierson, Bill; Kato, Cindy; Kurita, Hiroyuki

    2013-04-01

    The semiconductor industry is moving toward 20nm nodes and below. As the Overlay (OVL) budget is getting tighter at these advanced nodes, the importance in the accuracy in each nanometer of OVL error is critical. When process owners select OVL targets and methods for their process, they must do it wisely; otherwise the reported OVL could be inaccurate, resulting in yield loss. The same problem can occur when the target sampling map is chosen incorrectly, consisting of asymmetric targets that will cause biased correctable terms and a corrupted wafer. Total measurement uncertainty (TMU) is the main parameter that process owners use when choosing an OVL target per layer. Going towards the 20nm nodes and below, TMU will not be enough for accurate OVL control. KLA-Tencor has introduced a quality score named `Qmerit' for its imaging based OVL (IBO) targets, which is obtained on the-fly for each OVL measurement point in X & Y. This Qmerit score will enable the process owners to select compatible targets which provide accurate OVL values for their process and thereby improve their yield. Together with K-T Analyzer's ability to detect the symmetric targets across the wafer and within the field, the Archer tools will continue to provide an independent, reliable measurement of OVL error into the next advanced nodes, enabling fabs to manufacture devices that meet their tight OVL error budgets.

  5. Coal surface control for advanced fine coal flotation. Final report, October 1, 1988--March 31, 1992

    SciTech Connect

    Fuerstenau, D.W.; Hanson, J.S.; Diao, J.; Harris, G.H.; De, A.; Sotillo, F.; Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C.; Hu, W.; Zou, Y.; Chen, W.; Choudhry, V.; Shea, S.; Ghosh, A.; Sehgal, R.

    1992-03-01

    The initial goal of the research project was to develop methods of coal surface control in advanced froth flotation to achieve 90% pyritic sulfur rejection, while operating at Btu recoveries above 90% based on run-of-mine quality coal. Moreover, the technology is to concomitantly reduce the ash content significantly (to six percent or less) to provide a high-quality fuel to the boiler (ash removal also increases Btu content, which in turn decreases a coal`s emission potential in terms of lbs SO{sub 2}/million Btu). (VC)

  6. Economic convergence of environmental control and advanced technology

    SciTech Connect

    Bolli, R.E.; Haslbeck, J.L.

    1995-12-31

    Emerging advanced technologies for environmental control have many advantages over conventional, single pollutant removal processes. Features include high efficiencies, multiple pollutant control and zero waste streams. In the past, the economics for state-of-the-art emission control processes could not compete with proven, low-efficiency scrubbers that create throw away by-products. With the implementation of the Clean Air Act Amendments (CAAA), the entire economic environment has changed. If a single process can provide a facility`s compliance requirements for Title I, Title III and Title IV of the CAAA, its net costs can be lower than conventional technology and actually provide economic incentives for overcontrol. The emission allowance program is maturing and the annual revenues from overcontrol of SO{sub 2} are easily quantified. The economics of NO{sub x} control and offsets are currently being realized as EPA identified Title IV requirements, and facilities begin to realize the impact from Title I NO{sub x} control. Air toxic control from Title III could require yet a third control process for a facility to maintain emission compliance. The costs associated with single control strategies vs. multiple pollutant control processes will be discussed and compared. This paper will also present a specific application of the NOXSO Process and identify the potential advantages that can transform advanced technologies, like NOXSO, into the prudent solution for overall environmental compliance.

  7. Symptom clusters and quality of life among patients with advanced heart failure

    PubMed Central

    Yu, Doris SF; Chan, Helen YL; Leung, Doris YP; Hui, Elsie; Sit, Janet WH

    2016-01-01

    Objectives To identify symptom clusters among patients with advanced heart failure (HF) and the independent relationships with their quality of life (QoL). Methods This is the secondary data analysis of a cross-sectional study which interviewed 119 patients with advanced HF in the geriatric unit of a regional hospital in Hong Kong. The symptom profile and QoL were assessed by using the Edmonton Symptom Assessment Scale (ESAS) and the McGill QoL Questionnaire. Exploratory factor analysis was used to identify the symptom clusters. Hierarchical regression analysis was used to examine the independent relationships with their QoL, after adjusting the effects of age, gender, and comorbidities. Results The patients were at an advanced age (82.9 ± 6.5 years). Three distinct symptom clusters were identified: they were the distress cluster (including shortness of breath, anxiety, and depression), the decondition cluster (fatigue, drowsiness, nausea, and reduced appetite), and the discomfort cluster (pain, and sense of generalized discomfort). These three symptom clusters accounted for 63.25% of variance of the patients' symptom experience. The small to moderate correlations between these symptom clusters indicated that they were rather independent of one another. After adjusting the age, gender and comorbidities, the distress (β = −0.635, P < 0.001), the decondition (β = −0.148, P = 0.01), and the discomfort (β = −0.258, P < 0.001) symptom clusters independently predicted their QoL. Conclusions This study identified the distinctive symptom clusters among patients with advanced HF. The results shed light on the need to develop palliative care interventions for optimizing the symptom control for this life-limiting disease. PMID:27403150

  8. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in...

  9. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in...

  10. TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES

    EPA Science Inventory

    This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. he document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic drai...

  11. TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES

    EPA Science Inventory

    This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. The document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic dr...

  12. Controlling death: the false promise of advance directives.

    PubMed

    Perkins, Henry S

    2007-07-01

    Advance directives promise patients a say in their future care but actually have had little effect. Many experts blame problems with completion and implementation, but the advance directive concept itself may be fundamentally flawed. Advance directives simply presuppose more control over future care than is realistic. Medical crises cannot be predicted in detail, making most prior instructions difficult to adapt, irrelevant, or even misleading. Furthermore, many proxies either do not know patients' wishes or do not pursue those wishes effectively. Thus, unexpected problems arise often to defeat advance directives, as the case in this paper illustrates. Because advance directives offer only limited benefit, advance care planning should emphasize not the completion of directives but the emotional preparation of patients and families for future crises. The existentialist Albert Camus might suggest that physicians should warn patients and families that momentous, unforeseeable decisions lie ahead. Then, when the crisis hits, physicians should provide guidance; should help make decisions despite the inevitable uncertainties; should share responsibility for those decisions; and, above all, should courageously see patients and families through the fearsome experience of dying. PMID:17606961

  13. Report of the international workshop on quality control of monthly climate data

    SciTech Connect

    Not Available

    1993-12-31

    The National Climatic Data Center (NCDC), the US Department of Energy`s Carbon Dioxide Information Analysis Center, and the World Meteorological Organization (WMO) cosponsored an international quality control workshop for monthly climate data, October 5--6, 1993, at NCDC. About 40 scientists from around the world participated. The purpose of the meeting was to discuss and compare various quality control methods and to draft recommendations concerning the most successful systems. The near-term goal to improve quality control of CLIMAT messages for the NCDC/WMO publication Monthly Climatic Data for the World was sucessfully met. An electronic bulletin board was established to post errors and corrections. Improved communications among Global Telecommunication System hubs will be implemented. Advanced quality control algorithms were discussed and improvements were suggested. Further data exchanges were arranged.

  14. Advancing High-Quality Literacy Research in Juvenile Justice: Methodological and Practical Considerations

    ERIC Educational Resources Information Center

    Houchins, David E.; Jolivette, Kristine; Shippen, Margaret E.; Lambert, Richard

    2010-01-01

    Special education researchers have made noteworthy progress toward conceptualizing literacy research questions, designing quality studies, and disseminating the results of their research. These advancements have been made through the establishment and refinement of quality research indicators. Unfortunately, this progress has mostly eluded the…

  15. Beam quality of the ATA (Advanced Test Accelerator) injector

    SciTech Connect

    Boyd, J.K.; Caporaso, G.J.; Cole, A.G.; Weir, J.T.

    1987-01-01

    The beam quality of the ATA injector has been experimentally measured using a magnetic collimator. These measurements have been performed for a variety of magnetic field profiles, including field strengths where the collimator is shorter than a cyclotron wavelength. The experimental currents transmitted through the collimator have been predicted numerically. The numerical predictions and experimental data are in good agreement.

  16. Recent advances in omic technologies for meat quality management.

    PubMed

    Picard, B; Lebret, B; Cassar-Malek, I; Liaubet, L; Berri, C; Le Bihan-Duval, E; Hocquette, J F; Renand, G

    2015-11-01

    The knowledge of the molecular organization of living organisms evolved considerably during the last years. The methodologies associated also progressed with the development of the high-throughput sequencing (SNP array, RNAseq, etc.) and of genomic tools allowing the simultaneous analysis of hundreds or thousands of genes, proteins or metabolites. In farm animals, some proteins, mRNAs or metabolites whose abundance has been associated with meat quality traits have been detected in pig, cattle, chicken. They constitute biomarkers for the assessment and prediction of qualities of interest in each species, with potential biomarkers across species. The ongoing development of rapid methods will allow their use for decision-making and management tools in slaughterhouses, to better allocate carcasses or cuts to the appropriate markets. Besides, their application on living animals will help to improve genetic selection and to adapt a breeding system to fulfill expected quality level. The ultimate goal is to propose effective molecular tools for the management of product quality in meat production chains. PMID:26002117

  17. Recent advances in soil quality assessment in the United States

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soil quality is a concept that is useful as an educational and assessment tool. A number of assessment tools have been developed including: the Soil Conditioning Index (SCI), the Soil Management Assessment Framework (SMAF), the AgroEcosystem Performance Assessment Tool (AEPAT), and the new Cornell “...

  18. Proteomics Quality Control: Quality Control Software for MaxQuant Results.

    PubMed

    Bielow, Chris; Mastrobuoni, Guido; Kempa, Stefan

    2016-03-01

    Mass spectrometry-based proteomics coupled to liquid chromatography has matured into an automatized, high-throughput technology, producing data on the scale of multiple gigabytes per instrument per day. Consequently, an automated quality control (QC) and quality analysis (QA) capable of detecting measurement bias, verifying consistency, and avoiding propagation of error is paramount for instrument operators and scientists in charge of downstream analysis. We have developed an R-based QC pipeline called Proteomics Quality Control (PTXQC) for bottom-up LC-MS data generated by the MaxQuant1 software pipeline. PTXQC creates a QC report containing a comprehensive and powerful set of QC metrics, augmented with automated scoring functions. The automated scores are collated to create an overview heatmap at the beginning of the report, giving valuable guidance also to nonspecialists. Our software supports a wide range of experimental designs, including stable isotope labeling by amino acids in cell culture (SILAC), tandem mass tags (TMT), and label-free data. Furthermore, we introduce new metrics to score MaxQuant's Match-between-runs (MBR) functionality by which peptide identifications can be transferred across Raw files based on accurate retention time and m/z. Last but not least, PTXQC is easy to install and use and represents the first QC software capable of processing MaxQuant result tables. PTXQC is freely available at https://github.com/cbielow/PTXQC . PMID:26653327

  19. Immunotherapy and complexity: overcoming barriers to control of advanced cancer.

    PubMed

    Lage, Agustin

    2014-01-01

    Recent advances in fundamental immunology are changing paradigms for management of advanced cancer, now acknowledged as a chronic disease whose prevalence will increase, and one whose complexity makes it difficult to control. Immunotherapy is emerging as an alternative, with new monoclonal antibodies, therapeutic vaccines and deeper understanding of fundamental phenomena in the interaction between tumor and immune system. These novel insights concern mechanisms of programmed contraction of the immune response, characterization of molecular and cellular markers of immunosenescence, the dual role of inflammation, characterization of myeloid-derived suppressor cells and cancer stem cells, and the phenomena of immunogenic apoptosis and oncogene addiction. Additionally, new data drive a deeper understanding of four barriers to overcome in control of advanced cancer: the complexity of biological systems, tumor heterogeneity, tumor mutation rates, and human genome-environment mismatch. The new landscape points to six main strategies: manage advanced cancer as a chronic disease, find relevant molecular markers for patient stratification, develop a rationale for therapeutic combinations, target regulatory control loops in the immune system, expand mathematical modeling capacity, and evaluate complex health intervention packages in real-world conditions. These transitions in cancer immunotherapy research are illustrated in this paper through description of ongoing projects at Cuba's Molecular Immunology Center. PMID:25208123

  20. Spectrophotometric Procedure for Fast Reactor Advanced Coolant Manufacture Control

    NASA Astrophysics Data System (ADS)

    Andrienko, O. S.; Egorov, N. B.; Zherin, I. I.; Indyk, D. V.

    2016-01-01

    The paper describes a spectrophotometric procedure for fast reactor advanced coolant manufacture control. The molar absorption coefficient of dimethyllead dibromide with dithizone was defined as equal to 68864 ± 795 l·mole-1·cm-1, limit of detection as equal to 0.583 · 10-6 g/ml. The spectrophotometric procedure application range was found to be equal to 37.88 - 196.3 g. of dimethyllead dibromide in the sample. The procedure was used within the framework of the development of the method of synthesis of the advanced coolant for fast reactors.

  1. Research and control of advanced schistosomiasis japonica in China.

    PubMed

    Wu, Wei; Feng, Aicheng; Huang, Yixin

    2015-01-01

    Among the three main schistosomes (Schistosoma japonicum, Schistosoma mansoni, and Schistosoma haematobium) known to infect humans, S. japonicum causes the most serious pathological lesions. In China, only schistosomiasis japonica is transmitted. From the 1950s, massive epidemiological investigations and active control measures for schistosomiasis japonica have been carried out. At the early stage of schistosomiasis control program, there were about 12 million schistosomiasis patients, and about 5% of schistosomiasis patients belong to advanced patients, which was 600,000. After more than a half century of active schistosomiasis control work, the schistosomiasis situation has been reduced markedly. The nearest epidemiological investigation showed that, by the end of 2012, there were still 240,000 schistosomiasis patients with the descent rate of 98% and 30,000 advanced patients with the descent rate of 95%. This paper reviews the rich experiences of advanced schistosomiasis research and control in China, including that the epidemiology researches confirm there is a family aggregation of advanced schistosomiasis and advanced schistosomiasis patients have no significance to the schistosomiasis transmission in transmission-interrupted areas but still are an infection source in endemic areas; pathogenic mechanism researches verify that genetic factors and immunoregulation play important roles in the disease developing process; ultrasound image examinations are used not only in the diagnosis and differential diagnosis of advanced schistosomiasis but also in the guidance of treatment and evaluation of therapeutic effects and, furthermore, in the risk predictions of portal hypertension and upper gastrointestinal hemorrhage; clinical practices demonstrate that praziquantel can be used in most of advanced schistosomiasis patients, and the therapy not only can interrupt the schistosomiasis transmission somewhat but also is favorable for liver fibrosis improvement; the

  2. Advanced actuators for the control of large space structures

    NASA Technical Reports Server (NTRS)

    Downer, James; Hockney, Richard; Johnson, Bruce; Misovec, Kathleen

    1993-01-01

    The objective of this research was to develop advanced six-degree-of-freedom actuators employing magnetic suspensions suitable for the control of structural vibrations in large space structures. The advanced actuators consist of a magnetically suspended mass that has three-degrees-of-freedom in both translation and rotation. The most promising of these actuators featured a rotating suspended mass providing structural control torques in a manner similar to a control moment gyro (CMG). These actuators employ large-angle-magnetic suspensions that allow gimballing of the suspended mass without mechanical gimbals. Design definitions and sizing algorithms for these CMG type as well as angular reaction mass actuators based on multi-degree-of-freedom magnetic suspensions were developed. The performance of these actuators was analytically compared with conventional reaction mass actuators for a simple space structure model.

  3. International Quality Control Is No Easy Task

    ERIC Educational Resources Information Center

    Contreras, Alan

    2008-01-01

    In early March, the European Quality Assurance Register for Higher Education was established under what is called the Bologna Process. The 46 countries involved in the process seek to improve the quality and assessment of higher education throughout Europe, thus facilitating students' mobility among institutions and countries and enhancing…

  4. Technology to control variation in meat quality

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Consumers have certain expectations regarding the quality of the meat they purchase. Lean color is the primary quality attribute used by consumers to make purchase decisions. Similarly, repeat purchase decisions are generally a result of eating satisfaction, which is determined by the perceived va...

  5. Planner-Based Control of Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Muscettola, Nicola; Kortenkamp, David; Fry, Chuck; Bell, Scott

    2005-01-01

    The paper describes an approach to the integration of qualitative and quantitative modeling techniques for advanced life support (ALS) systems. Developing reliable control strategies that scale up to fully integrated life support systems requires augmenting quantitative models and control algorithms with the abstractions provided by qualitative, symbolic models and their associated high-level control strategies. This will allow for effective management of the combinatorics due to the integration of a large number of ALS subsystems. By focusing control actions at different levels of detail and reactivity we can use faster: simpler responses at the lowest level and predictive but complex responses at the higher levels of abstraction. In particular, methods from model-based planning and scheduling can provide effective resource management over long time periods. We describe reference implementation of an advanced control system using the IDEA control architecture developed at NASA Ames Research Center. IDEA uses planning/scheduling as the sole reasoning method for predictive and reactive closed loop control. We describe preliminary experiments in planner-based control of ALS carried out on an integrated ALS simulation developed at NASA Johnson Space Center.

  6. Why Do Electricity Policy and Competitive Markets Fail to Use Advanced PV Systems to Improve Distribution Power Quality?

    DOE PAGESBeta

    McHenry, Mark P.; Johnson, Jay; Hightower, Mike

    2016-01-01

    The increasing pressure for network operators to meet distribution network power quality standards with increasing peak loads, renewable energy targets, and advances in automated distributed power electronics and communications is forcing policy-makers to understand new means to distribute costs and benefits within electricity markets. Discussions surrounding how distributed generation (DG) exhibits active voltage regulation and power factor/reactive power control and other power quality capabilities are complicated by uncertainties of baseline local distribution network power quality and to whom and how costs and benefits of improved electricity infrastructure will be allocated. DG providing ancillary services that dynamically respond to the networkmore » characteristics could lead to major network improvements. With proper market structures renewable energy systems could greatly improve power quality on distribution systems with nearly no additional cost to the grid operators. Renewable DG does have variability challenges, though this issue can be overcome with energy storage, forecasting, and advanced inverter functionality. This paper presents real data from a large-scale grid-connected PV array with large-scale storage and explores effective mitigation measures for PV system variability. We discuss useful inverter technical knowledge for policy-makers to mitigate ongoing inflation of electricity network tariff components by new DG interconnection requirements or electricity markets which value power quality and control.« less

  7. Advanced X-ray Astrophysics Facility thermal control

    NASA Technical Reports Server (NTRS)

    Fritz, C. G.

    1983-01-01

    A conceptual active/passive thermal control system design is presented for the Advanced X-ray Astrophysics Facility (AXAF), where the design variables considered in system optimization were vehicle orientation for environmental extremes, thermal coating properties, and insulation materials. Because power and weight are at a premium, the design was limited to one power module, resulting in a thermal control limit of 441 W of regulated power. The present study has determined that all thermal control objectives for AXAF's instruments can be met by the design considered. The thermal resistance schematics employed in this conceptual study are presented, together with simulated performance characteristics.

  8. Development of Advanced Casing Treatments for Flow Control

    NASA Technical Reports Server (NTRS)

    Keith, Theo G., Jr.; Tsung, Fu-Lin

    2001-01-01

    Under the Base R&T and Ultra Efficient Engine Technology programs, the NASA-Goddard Space Flight Center Compressor Branch is investigating flow control strategies required to increase the loading and efficiency of core compressors while maintaining current levels of operability. Flow-control strategies being studied include advanced casing treatments, wall jet injection, and blade-tip injection for compressor stability enhancement, directed jets for surface boundary layer control, and vortex-generating devices. The use of computational fluid dynamics (CFD) simulations to assess the effectiveness of flow-control devices and to guide their design is a key element in this research. CFD simulations serve to screen potential flow-control concepts at a lower cost than executing physical experiments in turbomachinery facilities. CFD simulations also provide guidance in designing physical experiments for those flow control concepts, which appear promising.

  9. Does the quality of advanced prosthetic dentistry determine patient satisfaction?

    PubMed

    Hakestam, U; Karlsson, T; Söderfeldt, B; Rydén, O; Glantz, P O

    1997-12-01

    In a clinical follow-up study 42 patients were selected from an original sample of 335 individuals who had undergone extensive prosthetic treatment. The selection was done in accordance with a treatment satisfaction measure. The selected patients' appliances were classified in accordance with the California Dental Association (CDA) quality assessment system. Altogether, most of the new reconstructions were rated as satisfactory. The removable partial dentures had a somewhat higher share of non-acceptable appliances according to the CDA criteria. There was an association between the CDA categories and patient satisfaction. Using logistic regression analysis and knowing the CDA rating, we could correctly classify 67% of the patients with regard to the satisfaction measure. The satisfaction measure was modified on the basis of an interview, improving the model to 83% correctly classified. It was concluded that the technical quality of the prosthodontic treatment was associated with patient satisfaction. PMID:9477029

  10. Advanced CO2 removal process control and monitor instrumentation development

    NASA Technical Reports Server (NTRS)

    Heppner, D. B.; Dalhausen, M. J.; Klimes, R.

    1982-01-01

    A progam to evaluate, design and demonstrate major advances in control and monitor instrumentation was undertaken. A carbon dioxide removal process, one whose maturity level makes it a prime candidate for early flight demonstration was investigated. The instrumentation design incorporates features which are compatible with anticipated flight requirements. Current electronics technology and projected advances are included. In addition, the program established commonality of components for all advanced life support subsystems. It was concluded from the studies and design activities conducted under this program that the next generation of instrumentation will be greatly smaller than the prior one. Not only physical size but weight, power and heat rejection requirements were reduced in the range of 80 to 85% from the former level of research and development instrumentation. Using a microprocessor based computer, a standard computer bus structure and nonvolatile memory, improved fabrication techniques and aerospace packaging this instrumentation will greatly enhance overall reliability and total system availability.

  11. Recent Advances in Point-of-Access Water Quality Monitoring

    NASA Astrophysics Data System (ADS)

    Korostynska, O.; Arshak, K.; Velusamy, V.; Arshak, A.; Vaseashta, Ashok

    Clean water is one of our most valuable natural resources. In addition to providing safe drinking water it assures functional ecosystems that support fisheries and recreation. Human population growth and its associated increased demands on water pose risks to maintaining acceptable water quality. It is vital to assess source waters and the aquatic systems that receive inputs from industrial waste and sewage treatment plants, storm water systems, and runoff from urban and agricultural lands. Rapid and confident assessments of aquatic resources form the basis for sound environmental management. Current methods engaged in tracing the presence of various bacteria in water employ bulky laboratory equipment and are time consuming. Thus, real-time water quality monitoring is essential for National and International Health and Safety. Environmental water monitoring includes measurements of physical characteristics (e.g. pH, temperature, conductivity), chemical parameters (e.g. oxygen, alkalinity, nitrogen and phosphorus compounds), and abundance of certain biological taxa. Monitoring could also include assays of biological activity such as alkaline phosphatase, tests for toxins such as microcystins and direct measurements of pollutants such as heavy metals or hydrocarbons. Real time detection can significantly reduce the level of damage and also the cost to remedy the problem. This paper presents overview of state-of-the-art methods and devices used for point-of-access water quality monitoring and suggest further developments in this area.

  12. Advance care planning: A systematic review of randomised controlled trials conducted with older adults.

    PubMed

    Weathers, Elizabeth; O'Caoimh, Rónán; Cornally, Nicola; Fitzgerald, Carol; Kearns, Tara; Coffey, Alice; Daly, Edel; O'Sullivan, Ronan; McGlade, Ciara; Molloy, D William

    2016-09-01

    Advance care planning (ACP), involving discussions between patients, families and healthcare professionals on future healthcare decisions, in advance of anticipated impairment in decision-making capacity, improves satisfaction and end-of-life care while respecting patient autonomy. It usually results in the creation of a written advanced care directive (ACD). This systematic review examines the impact of ACP on several outcomes (including symptom management, quality of care and healthcare utilisation) in older adults (>65years) across all healthcare settings. Nine randomised controlled trials (RCTs) were identified by searches of the CINAHL, PubMed and Cochrane databases. A total of 3646 older adults were included (range 72-88 years). Seven studies were conducted with community dwellers and the other two RCTs were conducted in nursing homes. Most studies did not implement a standardised ACD, or measure the impact on quality of end-of-life care or on the death and dying experience. All studies had some risk of bias, with most scoring poorly on the Oxford Quality Scale. While ACP interventions are well received by older adults and generally have positive effects on outcomes, this review highlights the need for well-designed RCTs that examine the economic impact of ACP and its effect on quality of care in nursing homes and other sectors. PMID:27451328

  13. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... management of quality, including: (1) Requirements for the production of quality data and the use of quality... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization..., manufacturing, and fabrication, inspections are adequate to ensure control of finished article...

  14. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... management of quality, including: (1) Requirements for the production of quality data and the use of quality... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization..., manufacturing, and fabrication, inspections are adequate to ensure control of finished article...

  15. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... management of quality, including: (1) Requirements for the production of quality data and the use of quality... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization..., manufacturing, and fabrication, inspections are adequate to ensure control of finished article...

  16. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... management of quality, including: (1) Requirements for the production of quality data and the use of quality... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization..., manufacturing, and fabrication, inspections are adequate to ensure control of finished article...

  17. Integrated Quality Control Measurement Project. Findings and Corrective Actions.

    ERIC Educational Resources Information Center

    Price Waterhouse and Co., New York, NY.

    The Integrated Quality Control Measurement Project (IQCMP) of the U.S. Department of Education measured the quality of awards distributed during the 1988-89 award year under the three major Title IV programs: the Pell Grant program, the Campus-Based programs, and the Stafford Loan program, in order to evaluate and improve the quality of the…

  18. Food and Nutrition Services Quality Control Management Program.

    ERIC Educational Resources Information Center

    Wimsatt-Fraim, Teresa S.

    A program was conducted to improve the quality of food service through the training of 44 food and nutrition service employees in a 200-bed hospital. A 12-week quality control program was implemented to address four key areas: food temperatures, food accuracy, food quality, and dietary personnel. Learning strategies, emphasizing critical thinking…

  19. Teaching Quality Control with Chocolate Chip Cookies

    ERIC Educational Resources Information Center

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  20. Space Shuttle flying qualities and flight control system assessment study

    NASA Technical Reports Server (NTRS)

    Myers, T. T.; Johnston, D. E.; Mcruer, D.

    1982-01-01

    The suitability of existing and proposed flying quality and flight control system criteria for application to the space shuttle orbiter during atmospheric flight phases was assessed. An orbiter experiment for flying qualities and flight control system design criteria is discussed. Orbiter longitudinal and lateral-directional flying characteristics, flight control system lag and time delay considerations, and flight control manipulator characteristics are included. Data obtained from conventional aircraft may be inappropriate for application to the shuttle orbiter.

  1. Quality assurance and risk management: Perspectives on Human Factors Certification of Advanced Aviation Systems

    NASA Technical Reports Server (NTRS)

    Taylor, Robert M.; Macleod, Iain S.

    1994-01-01

    This paper is based on the experience of engineering psychologists advising the U.K. Ministry of Defense (MoD) on the procurement of advanced aviation systems that conform to good human engineering (HE) practice. Traditional approaches to HE in systems procurement focus on the physical nature of the human-machine interface. Advanced aviation systems present increasingly complex design requirements for human functional integration, information processing, and cognitive task performance effectiveness. These developing requirements present new challenges for HE quality assurance (QA) and risk management, requiring focus on design processes as well as on design content or product. A new approach to the application of HE, recently adopted by NATO, provides more systematic ordering and control of HE processes and activities to meet the challenges of advanced aircrew systems design. This systematic approach to HE has been applied by MoD to the procurement of mission systems for the Royal Navy Merlin helicopter. In MoD procurement, certification is a judicial function, essentially independent of the service customer and industry contractor. Certification decisions are based on advice from MoD's appointed Acceptance Agency. Test and evaluation (T&E) conducted by the contractor and by the Acceptance Agency provide evidence for certification. Certification identifies limitations of systems upon release to the service. Evidence of compliance with HE standards traditionally forms the main basis of HE certification and significant non-compliance could restrict release. The systems HE approach shows concern for the quality of processes as well as for the content of the product. Human factors certification should be concerned with the quality of HE processes as well as products. Certification should require proof of process as well as proof of content and performance. QA criteria such as completeness, consistency, timeliness, and compatibility provide generic guidelines for

  2. Advanced Control Design for Wind Turbines; Part I: Control Design, Implementation, and Initial Tests

    SciTech Connect

    Wright, A. D.; Fingersh, L. J.

    2008-03-01

    The purpose of this report is to give wind turbine engineers information and examples of the design, testing through simulation, field implementation, and field testing of advanced wind turbine controls.

  3. Recent advances in active control of aircraft cabin noise

    NASA Astrophysics Data System (ADS)

    Mathur, Gopal; Fuller, Christopher

    2002-11-01

    Active noise control techniques can provide significant reductions in aircraft interior noise levels without the structural modifications or weight penalties usually associated with passive techniques, particularly for low frequency noise. Our main objective in this presentation is to give a review of active control methods and their applications to aircraft cabin noise reduction with an emphasis on recent advances and challenges facing the noise control engineer in the practical application of these techniques. The active noise control method using secondary acoustic sources, e.g., loudspeakers, as control sources for tonal noise reduction is first discussed with results from an active noise control flight test demonstration. An innovative approach of applying control forces directly to the fuselage structure using piezoelectric actuators, known as active structural acoustic control (ASAC), to control cabin noise is then presented. Experimental results from laboratory ASAC tests conducted on a full-scale fuselage and from flight tests on a helicopter will be discussed. Finally, a hybrid active/passive noise control approach for achieving significant broadband noise reduction will be discussed. Experimental results of control of broadband noise transmission through an aircraft structure will be presented.

  4. Advanced interaction media in nuclear power plant control rooms.

    PubMed

    Stephane, Lucas

    2012-01-01

    The shift from analog to digital Instruments (related mainly to information visualization) and Controls in Nuclear Power Plant Main Control Rooms (NPP MCR) is a central current topic of investigation. In NPP MCR, digitalization was implemented gradually, analog and digital systems still coexisting for the two main systems related to safety--Safety Instruments and Control System (SICS) and Process Instruments and Controls System (PICS). My ongoing research focuses on the introduction of Advanced Interaction Media (AIM) such as stereoscopic 3D visualization and multi-touch surfaces in control rooms. This paper proposes a Safety-Centric approach for gathering the Design Rationale needed in the specification of such novel AIM concepts as well as their evaluation through user tests. Beyond methodological research, the final output of the current research is to build an experimental simulator aiming to enhance improvements in Human-Systems Integration (HSI). This paper provides an overview of the topics under consideration. PMID:22317419

  5. ACTS TDMA network control. [Advanced Communication Technology Satellite

    NASA Technical Reports Server (NTRS)

    Inukai, T.; Campanella, S. J.

    1984-01-01

    This paper presents basic network control concepts for the Advanced Communications Technology Satellite (ACTS) System. Two experimental systems, called the low-burst-rate and high-burst-rate systems, along with ACTS ground system features, are described. The network control issues addressed include frame structures, acquisition and synchronization procedures, coordinated station burst-time plan and satellite-time plan changes, on-board clock control based on ground drift measurements, rain fade control by means of adaptive forward-error-correction (FEC) coding and transmit power augmentation, and reassignment of channel capacities on demand. The NASA ground system, which includes a primary station, diversity station, and master control station, is also described.

  6. Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan : ASC software quality engineering practices Version 3.0.

    SciTech Connect

    Turgeon, Jennifer L.; Minana, Molly A.; Hackney, Patricia; Pilch, Martin M.

    2009-01-01

    The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in the US Department of Energy/National Nuclear Security Agency (DOE/NNSA) Quality Criteria, Revision 10 (QC-1) as 'conformance to customer requirements and expectations'. This quality plan defines the SNL ASC Program software quality engineering (SQE) practices and provides a mapping of these practices to the SNL Corporate Process Requirement (CPR) 001.3.6; 'Corporate Software Engineering Excellence'. This plan also identifies ASC management's and the software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals. This SNL ASC Software Quality Plan establishes the signatories commitments to improving software products by applying cost-effective SQE practices. This plan enumerates the SQE practices that comprise the development of SNL ASC's software products and explains the project teams opportunities for tailoring and implementing the practices.

  7. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Production quality control requirements. 164.019-13 Section 164.019-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Personal Flotation Device Components § 164.019-13 Production quality control...

  8. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable to the FAA that ensures the airworthiness of the articles on which the repair station or any of...

  9. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable to the FAA that ensures the airworthiness of the articles on which the repair station or any of...

  10. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable to the FAA that ensures the airworthiness of the articles on which the repair station or any of...

  11. Quality Control Study of the GSL Reinsurance System. Final Report.

    ERIC Educational Resources Information Center

    Advanced Technology, Inc., Reston, VA.

    A quality control plan for the U.S. Department of Education's Guaranteed Student Loan (GSL) reinsurance process was developed. To identify existing errors, systems documentation and past analyses of the reinsurance system were analyzed, and interviews were conducted. Corrective actions were proposed, and a quality control checklist was developed…

  12. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section 58.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a)...

  13. Building Science Corporation's Building America Quality Control Checklist

    SciTech Connect

    2008-10-05

    The Building America Quality Control Checklist has been developed as both a guide to assist in the transition to high performance home building, and as a simplified tool to be used as part of any builder's on-site quality control procedures.

  14. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Laboratory and quality control tests. 58.442 Section 58.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a)...

  15. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Laboratory and quality control tests. 58.442 Section 58.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a)...

  16. Artificial Intelligence Approach to Support Statistical Quality Control Teaching

    ERIC Educational Resources Information Center

    Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

    2006-01-01

    Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

  17. 7 CFR 58.733 - Quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good...

  18. Microeconomics of advanced process window control for 50-nm gates

    NASA Astrophysics Data System (ADS)

    Monahan, Kevin M.; Chen, Xuemei; Falessi, Georges; Garvin, Craig; Hankinson, Matt; Lev, Amir; Levy, Ady; Slessor, Michael D.

    2002-07-01

    Fundamentally, advanced process control enables accelerated design-rule reduction, but simple microeconomic models that directly link the effects of advanced process control to profitability are rare or non-existent. In this work, we derive these links using a simplified model for the rate of profit generated by the semiconductor manufacturing process. We use it to explain why and how microprocessor manufacturers strive to avoid commoditization by producing only the number of dies required to satisfy the time-varying demand in each performance segment. This strategy is realized using the tactic known as speed binning, the deliberate creation of an unnatural distribution of microprocessor performance that varies according to market demand. We show that the ability of APC to achieve these economic objectives may be limited by variability in the larger manufacturing context, including measurement delays and process window variation.

  19. For and against a European quality control of training.

    PubMed

    Dimitrakakis, C; Michalas, S

    2001-01-01

    In a world of medicine that evolves more and more rapidly, sufficient quality of education in the arts and crafts of our discipline and control of this quality are essential for the progress and vitality of Ob/Gyn. There are variations in training within European countries but with the aim of harmonization in training programmes and the flexibility of quality control mechanisms we will meet our objective that is the high standards in the care of woman throughout Europe. PMID:11205701

  20. Quality assessment of digested sludges produced by advanced stabilization processes.

    PubMed

    Braguglia, C M; Coors, A; Gallipoli, A; Gianico, A; Guillon, E; Kunkel, U; Mascolo, G; Richter, E; Ternes, T A; Tomei, M C; Mininni, G

    2015-05-01

    The European Union (EU) Project Routes aimed to discover new routes in sludge stabilization treatments leading to high-quality digested sludge, suitable for land application. In order to investigate the impact of different enhanced sludge stabilization processes such as (a) thermophilic digestion integrated with thermal hydrolysis pretreatment (TT), (b) sonication before mesophilic/thermophilic digestion (UMT), and (c) sequential anaerobic/aerobic digestion (AA) on digested sludge quality, a broad class of conventional and emerging organic micropollutants as well as ecotoxicity was analyzed, extending the assessment beyond the parameters typically considered (i.e., stability index and heavy metals). The stability index was improved by adding aerobic posttreatment or by operating dual-stage process but not by pretreatment integration. Filterability was worsened by thermophilic digestion, either alone (TT) or coupled with mesophilic digestion (UMT). The concentrations of heavy metals, present in ranking order Zn > Cu > Pb > Cr ~ Ni > Cd > Hg, were always below the current legal requirements for use on land and were not removed during the processes. Removals of conventional and emerging organic pollutants were greatly enhanced by performing double-stage digestion (UMT and AA treatment) compared to a single-stage process as TT; the same trend was found as regards toxicity reduction. Overall, all the digested sludges exhibited toxicity to the soil bacterium Arthrobacter globiformis at concentrations about factor 100 higher than the usual application rate of sludge to soil in Europe. For earthworms, a safety margin of factor 30 was generally achieved for all the digested samples. PMID:24903249

  1. Applications of fiber optic sensors in advanced engine controls

    NASA Astrophysics Data System (ADS)

    Nitka, Edward F., II

    1989-06-01

    Measured parameters, operating ranges, accuracy requirements, environmental constraints, and speed of response of fiber optic sensors are identified for three categories of engines. The three engine categories are: (1) current turbojet, turbofan, and turboprop engines; (2) next generation and turbofan engines to be built in the 1990s; and (3) advanced supersonic/hypersonic engines represented by ramjet, scramjet, and air-turbo-ramjet concepts. The key development and test efforts in engine control applications of fiber optic sensors are discussed.

  2. Coal surface control for advanced fine coal flotation

    SciTech Connect

    Fuerstenau, D.W.; Sastry, K.V.; Hanson, J.S.; Harris, G.; Sotillo, F.; Diao, J.; De, A. ); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. ); Hu, Weibai; Zou, Y.; Chen, W. ); Choudhry, V.; Sehgal, R.; Ghosh, A. )

    1991-03-22

    The main goal of the project is to characterize the surface and control the behavior of coal during advanced flotation processing in order to achieve an overall objective of near-total pyritic sulfur removal with a high Btu recovery. Also, investigation of the effects of weathering on the surface characteristics of coal is another important aspect of this project. The effect of butanol, dodecane, lime, calcium cyanide, hydrogen peroxide, and ph on flotation performance is discussed. 2 refs., 26 figs., 18 tabs.

  3. Definition study for temperature control in advanced protein crystal growth

    NASA Technical Reports Server (NTRS)

    Nyce, Thomas A.; Rosenberger, Franz; Sowers, Jennifer W.; Monaco, Lisa A.

    1990-01-01

    Some of the technical requirements for an expedient application of temperature control to advanced protein crystal growth activities are defined. Lysozome was used to study the effects of temperature ramping and temperature gradients for nucleation/dissolution and consecutive growth of sizable crystals and, to determine a prototype temperature program. The solubility study was conducted using equine serum albumin (ESA) which is an extremely stable, clinically important protein due to its capability to bind and transport many different small ions and molecules.

  4. A flexible architecture for advanced process control solutions

    NASA Astrophysics Data System (ADS)

    Faron, Kamyar; Iourovitski, Ilia

    2005-05-01

    Advanced Process Control (APC) is now mainstream practice in the semiconductor manufacturing industry. Over the past decade and a half APC has evolved from a "good idea", and "wouldn"t it be great" concept to mandatory manufacturing practice. APC developments have primarily dealt with two major thrusts, algorithms and infrastructure, and often the line between them has been blurred. The algorithms have evolved from very simple single variable solutions to sophisticated and cutting edge adaptive multivariable (input and output) solutions. Spending patterns in recent times have demanded that the economics of a comprehensive APC infrastructure be completely justified for any and all cost conscious manufacturers. There are studies suggesting integration costs as high as 60% of the total APC solution costs. Such cost prohibitive figures clearly diminish the return on APC investments. This has limited the acceptance and development of pure APC infrastructure solutions for many fabs. Modern APC solution architectures must satisfy the wide array of requirements from very manual R&D environments to very advanced and automated "lights out" manufacturing facilities. A majority of commercially available control solutions and most in house developed solutions lack important attributes of scalability, flexibility, and adaptability and hence require significant resources for integration, deployment, and maintenance. Many APC improvement efforts have been abandoned and delayed due to legacy systems and inadequate architectural design. Recent advancements (Service Oriented Architectures) in the software industry have delivered ideal technologies for delivering scalable, flexible, and reliable solutions that can seamlessly integrate into any fabs" existing system and business practices. In this publication we shall evaluate the various attributes of the architectures required by fabs and illustrate the benefits of a Service Oriented Architecture to satisfy these requirements. Blue

  5. Testing State-Space Controls for the Controls Advanced Research Turbine: Preprint

    SciTech Connect

    Wright, A. D.; Fingersh, L. J.; Balas, M. J.

    2006-01-01

    Control can improve wind turbine performance by enhancing energy capture and reducing dynamic loads. At the National Renewable Energy Laboratory, we are implementing and testing state-space controls on the Controls Advanced Research Turbine (CART), a turbine specifically configured to test advanced controls. We show the design of control systems to regulate turbine speed in Region 3 using rotor collective pitch and reduce dynamic loads in Regions 2 and 3 using generator torque. These controls enhance damping in the first drive train torsion mode. We base these designs on sensors typically used in commercial turbines. We evaluate the performance of these controls by showing field test results. We also compare results from these modern controllers to results from a baseline proportional integral controller for the CART. Finally, we report conclusions to this work and outline future studies.

  6. State of Health and Quality of Life of Women at Advanced Age.

    PubMed

    Pinkas, Jarosław; Gujski, Mariusz; Humeniuk, Ewa; Raczkiewicz, Dorota; Bejga, Przemysław; Owoc, Alfred; Bojar, Iwona

    2016-01-01

    BACKGROUND Evaluation of the state of health, quality of life, and relationship between the level of the quality of life and health status in a group of women at advanced age (90 and more years) in Poland. MATERIAL AND METHODS The study was conducted in 2014 in an all-Polish sample of 870 women aged 90 and over. The research instruments were: the author's questionnaire, and standardized tests: Katz index of independence in Activities of Daily Living (ADL), Abbreviated Mental Test Score (AMTS), The World Health Organization Quality of Life (WHOQOL) - BREF. The results of the study were statistically analyzed using significant t test for mean and regression analysis. RESULTS The majority of women at advanced age suffered from chronic pain (76%) and such major geriatric problems as hypoacusis (81%), visual disturbances (69%) and urinary incontinence (60%), the minority - fall and fainting (39%) as well as stool incontinence (17%), severe functional and cognitive impairment (24% and 10% respectively). Women at advanced age assessed positively for overall quality of life (mean 3.3 on 1-5 scale), social relationships (3.5) and environment (3.2), but negatively - general, physical and psychological health (2.7, 2.7 and 2.8 respectively). The presence of chronic pain and major geriatric problems: urinary and stool incontinences, falls and fainting, visual disturbances and hypoacusis significantly decreases overall quality of life, general, physical and psychological health, social relationships and environment of women at advanced age. Overall quality of life, general, physical and psychological health, social relationships and environment correlate to functional and cognitive impairments of women at advanced age. CONCLUSIONS Quality of life of women at advanced age decreased if chronic pain, major geriatric problems as well as functional and cognitive impairments occur. PMID:27580565

  7. 40 CFR Appendix B to Part 75 - Quality Assurance and Quality Control Procedures

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Quality Assurance and Quality Control Procedures B Appendix B to Part 75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Pt. 75, App. B Appendix B to Part 75—Quality...

  8. Screening studies of advanced control concepts for airbreathing engines

    NASA Technical Reports Server (NTRS)

    Ouzts, Peter J.; Lorenzo, Carl F.; Merrill, Walter C.

    1993-01-01

    The application of advanced control concepts to airbreathing engines may yield significant improvements in aircraft/engine performance and operability. Accordingly, the NASA Lewis Research Center has conducted screening studies of advanced control concepts for airbreathing engines to determine their potential impact on turbine engine performance and operability. The purpose of the studies was to identify concepts which offered high potential yet may incur high research and development risk. A target suite of proposed concepts was formulated by NASA and industry. These concepts were evaluated in a two phase study to quantify each concept's impact on desired engine characteristics. To aid in the evaluation, three target aircraft/engine combinations were considered: a military high performance fighter mission, a high speed civil transport mission, and a civil tiltrotor mission. Each of the advanced control concepts considered in the study were defined and described. The concept's potential impact on engine performance was determined. Relevant figures of merit on which to evaluate the concepts were also determined. Finally, the concepts were ranked with respect to the target aircraft/engine missions.

  9. Screening studies of advanced control concepts for airbreathing engines

    NASA Technical Reports Server (NTRS)

    Ouzts, Peter J.; Lorenzo, Carl F.; Merrill, Walter C.

    1992-01-01

    The application of advanced control concepts to airbreathing engines may yield significant improvements in aircraft/engine performance and operability. Accordingly, the NASA Lewis Research Center has conducted screening studies of advanced control concepts for airbreathing engines to determine their potential impact on turbine engine performance and operability. The purpose of the studies was to identify concepts which offered high potential yet may incur high research and development risk. A target suite of proposed concepts was formulated by NASA and industry. These concepts were evaluated in a two phase study to quantify each concept's impact on desired engine characteristics. To aid in the evaluation, three target aircraft/engine combinations were considered: a military high performance fighter mission, a high speed civil transport mission, and a civil tiltrotor mission. Each of the advanced control concepts considered in the study were defined and described. The concept's potential impact on engine performance was determined. Relevant figures of merit on which to evaluate the concepts were also determined. Finally, the concepts were ranked with respect to the target aircraft/engine missions.

  10. Improved safety in advanced control complexes, without side effects

    SciTech Connect

    Harmon, D.L.

    1997-12-01

    If we only look for a moment at the world around us, it is obvious that advances in digital electronic equipment and Human-System Interface (HSI) technology are occurring at a phenomenal pace. This is evidenced from our home entertainment systems to the dashboard and computer-based operation of our new cars. Though the nuclear industry has less vigorously embraced these advances, their application is being implemented through individual upgrades to current generation nuclear plants and as plant-wide control complexes for advanced plants. In both venues modem technology possesses widely touted advantages for improving plant availability as well as safety. The well-documented safety benefits of digital Instrumentation and Controls (I&C) include higher reliability resulting from redundancy and fault tolerance, inherent self-test and self-diagnostic capabilities which have replaced error-prone human tasks, resistance to setpoint drift increasing available operating margins, and the ability to run complex, real-time, computer-based algorithms directly supporting an operator`s monitoring and control task requirements. 22 refs., 3 figs., 5 tabs.

  11. Advanced Environmental Monitoring and Control Program: Technology Development Requirements

    NASA Technical Reports Server (NTRS)

    Jan, Darrell (Editor); Seshan, Panchalam (Editor); Ganapathi, Gani (Editor); Schmidt, Gregory (Editor); Doarn, Charles (Editor)

    1996-01-01

    Human missions in space, from the International Space Station on towards potential human exploration of the moon, Mars and beyond into the solar system, will require advanced systems to maintain an environment that supports human life. These systems will have to recycle air and water for many months or years at a time, and avoid harmful chemical or microbial contamination. NASA's Advanced Environmental Monitoring and Control program has the mission of providing future spacecraft with advanced, integrated networks of microminiaturized sensors to accurately determine and control the physical, chemical and biological environment of the crew living areas. This document sets out the current state of knowledge for requirements for monitoring the crew environment, based on (1) crew health, and (2) life support monitoring systems. Both areas are updated continuously through research and space mission experience. The technologies developed must meet the needs of future life support systems and of crew health monitoring. These technologies must be inexpensive and lightweight, and use few resources. Using these requirements to continue to push the state of the art in miniaturized sensor and control systems will produce revolutionary technologies to enable detailed knowledge of the crew environment.

  12. Advanced Rooftop Control (ARC) Retrofit: Field-Test Results

    SciTech Connect

    Wang, Weimin; Katipamula, Srinivas; Ngo, Hung; Underhill, Ronald M.; Taasevigen, Danny J.; Lutes, Robert G.

    2013-07-31

    The multi-year research study was initiated to find solutions to improve packaged equipment operating efficiency in the field. Pacific Northwest National Laboratory (PNNL), with funding from the U.S. Department of Energy’s (DOE’s) Building Technologies Office (BTO) and Bonneville Power Administration (BPA) conducted this research, development and demonstration (RD&D) study. Packaged equipment with constant speed supply fans is designed to provide ventilation at the design rate at all times when the fan is operating as required by building code. Although there are a number of hours during the day when a building may not be fully occupied or the need for ventilation is lower than designed, the ventilation rate cannot be adjusted easily with a constant speed fan. Therefore, modulating the supply fan in conjunction with demand controlled ventilation (DCV) will not only reduce the coil energy but also reduce the fan energy. The objective of this multi-year research, development and demonstration project was to determine the magnitude of energy savings achievable by retrofitting existing packaged rooftop air conditioners with advanced control strategies not ordinarily used for packaged units. First, through detailed simulation analysis, it was shown that significant energy (between 24% and 35%) and cost savings (38%) from fan, cooling and heating energy consumption could be realized when packaged air conditioning units with gas furnaces are retrofitted with advanced control packages (combining multi-speed fan control, integrated economizer controls and DCV). The simulation analysis also showed significant savings for heat pumps (between 20% and 60%). The simulation analysis was followed by an extensive field test of a retrofittable advanced rooftop unit (RTU) controller.

  13. How Oncologists and Their Patients with Advanced Cancer Communicate about Health-Related Quality of Life

    PubMed Central

    Rodriguez, Keri L.; Bayliss, Nichole; Alexander, Stewart C.; Jeffreys, Amy S.; Olsen, Maren K.; Pollak, Kathryn I.; Kennifer, Sarah L.; Tulsky, James A.; Arnold, Robert M.

    2011-01-01

    Objective To describe the content and frequency of communication about health-related quality of life (HRQOL) during outpatient encounters between oncologists and their patients with advanced cancer. Methods We coded for HRQOL talk in a subset of audio recorded conversations (each previously found to contain prognostic talk by the oncologist) from the Study of Communication in Oncologist-Patient Encounters (SCOPE) Trial, a randomized controlled trial conducted from 2003 to 2008 in two large U.S. academic medical centers and one Veterans Affairs Medical Center. Results Seventy-three encounters that involved 70 patients and 37 oncologists. Patients were more likely to be female (53%), white (86%), married (78%), and possessing some college education (62%). Most oncologists were male (78%) and white (78%). Mean ages were 59 years for patients and 44 years for oncologists. Every encounter included some talk about HRQOL and HRQOL discussions made up, on average, 25% of the visit time. HRQOL segments described symptoms (50%); general HRQOL (27%); and the following concerns: physical (27%), functional (22%), psychological (9%), social (7%), spiritual (1%), and other (28%). Topics included treatment (56%), disease (14%), and testing (3%), and conversations focused on past (44%), present (68%), and future HRQOL (59%). Conclusions HRQOL discussions between oncologists and patients are common, but the emphasis is often on treatment (e.g., side effects) and symptoms (e.g., pain) even in patients with advanced disease. Given the often intense emotional experience of patients with advanced cancer, oncologists may need to pay more attention to psychological, social, and spiritual HRQOL concerns. PMID:19449348

  14. APPLICATION OF RESERVOIR CHARACTERIZATION AND ADVANCED TECHNOLOGY TO IMPROVE RECOVERY AND ECONOMICS IN A LOWER QUALITY SHALLOW SHELF SANANDRES RESERVOIR

    SciTech Connect

    Unknown

    2003-01-15

    The Class 2 Project at West Welch was designed to demonstrate the use of advanced technologies to enhance the economics of improved oil recovery (IOR) projects in lower quality Shallow Shelf Carbonate (SSC) reservoirs, resulting in recovery of additional oil that would otherwise be left in the reservoir at project abandonment. Accurate reservoir description is critical to the effective evaluation and efficient design of IOR projects in the heterogeneous SSC reservoirs. Therefore, the majority of Budget Period 1 was devoted to reservoir characterization. Technologies being demonstrated include: (1) Advanced petrophysics; (2) Three-dimensional (3-D) seismic; (3) Crosswell bore tomography; (4) Advanced reservoir simulation; (5) Carbon dioxide (CO{sub 2}) stimulation treatments; (6) Hydraulic fracturing design and monitoring; (7) Mobility control agents.

  15. Reliability, Safety and Error Recovery for Advanced Control Software

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.

    2003-01-01

    For long-duration automated operation of regenerative life support systems in space environments, there is a need for advanced integration and control systems that are significantly more reliable and safe, and that support error recovery and minimization of operational failures. This presentation outlines some challenges of hazardous space environments and complex system interactions that can lead to system accidents. It discusses approaches to hazard analysis and error recovery for control software and challenges of supporting effective intervention by safety software and the crew.

  16. Advancing the Quality of Solar Occultation Retrievals through Solar Imaging

    NASA Astrophysics Data System (ADS)

    Gordley, L. L.; Hervig, M. E.; Marshall, B. T.; Russell, J. E.; Bailey, S. M.; Brown, C. W.; Burton, J. C.; Deaver, L. E.; Magill, B. E.; McHugh, M. J.; Paxton, G. J.; Thompson, R. E.

    2008-12-01

    The quality of retrieved profiles (e.g. mixing ratio, temperature, pressure, and extinction) from solar occultation sensors is strongly dependent on the angular fidelity of the measurements. The SOFIE instrument, launched on-board the AIM (Aeronomy of Ice in the Mesosphere) satellite on April 25, 2007, was designed to provide very high precision broadband measurements for the study of Polar Mesospheric Clouds (PMCs), that appear near 83km, just below the high latitude summer mesopause. The SOFIE instrument achieves an unprecedented angular fidelity by imaging the sun on a 2D detector array and tracking the edges with an uncertainty of <0.1 arc seconds. This makes possible retrieved profiles of vertical high resolution mixing ratios, refraction base temperature and pressure from tropopause to lower mesosphere, and transmission with accuracy sufficient to infer cosmic smoke extinction. Details of the approach and recent results will be presented.

  17. Coal surface control for advanced physical fine coal cleaning technologies

    SciTech Connect

    Morsi, B.I.; Chiang, S.H.; Sharkey, A.; Blachere, J.; Klinzing, G.; Araujo, G.; Cheng, Y.S.; Gray, R.; Streeter, R.; Bi, H.; Campbell, P.; Chiarlli, P.; Ciocco, M.; Hittle, L.; Kim, S.; Kim, Y.; Perez, L.; Venkatadri, R.

    1992-01-01

    This final report presents the research work carried out on the Coal Surface Control for Advanced Physical Fine Coal Cleaning Technologies project, sponsored by the US Department of Energy, Pittsburgh Energy Technology Center (DOE/PETC). The project was to support the engineering development of the selective agglomeration technology in order to reduce the sulfur content of US coals for controlling SO[sub 2] emissions (i.e., acid rain precursors). The overall effort was a part of the DOE/PETCs Acid Rain Control Initiative (ARCI). The overall objective of the project is to develop techniques for coal surface control prior to the advanced physical fine coal cleaning process of selective agglomeration in order to achieve 85% pyrite sulfur rejection at an energy recovery greater than 85% based on run-of-mine coal. The surface control is meant to encompass surface modification during grinding and laboratory beneficiation testing. The project includes the following tasks: Project planning; methods for analysis of samples; development of standard beneficiation test; grinding studies; modification of particle surface; and exploratory R D and support. The coal samples used in this project include three base coals, Upper Freeport - Indiana County, PA, Pittsburgh NO. 8 - Belmont County, OH, and Illinois No. 6 - Randolph County, IL, and three additional coals, Upper Freeport - Grant County- WV, Kentucky No. 9 Hopkins County, KY, and Wyodak - Campbell County, WY. A total of 149 drums of coal were received.

  18. System Engineering and Integration of Controls for Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Overland, David; Hoo, Karlene; Ciskowski, Marvin

    2006-01-01

    The Advanced Integration Matrix (AIM) project at the Johnson Space Center (JSC) was chartered to study and solve systems-level integration issues for exploration missions. One of the first issues identified was an inability to conduct trade studies on control system architectures due to the absence of mature evaluation criteria. Such architectures are necessary to enable integration of regenerative life support systems. A team was formed to address issues concerning software and hardware architectures and system controls.. The team has investigated what is required to integrate controls for the types of non-linear dynamic systems encountered in advanced life support. To this end, a water processing bioreactor testbed is being developed which will enable prototyping and testing of integration strategies and technologies. Although systems such as the water bioreactors exhibit the complexities of interactions between control schemes most vividly, it is apparent that this behavior and its attendant risks will manifest itself among any set of interdependent autonomous control systems. A methodology for developing integration requirements for interdependent and autonomous systems is a goal of this team and this testbed. This paper is a high-level summary of the current status of the investigation, the issues encountered, some tentative conclusions, and the direction expected for further research.

  19. Development of an advanced pitch active control system for a wide body jet aircraft

    NASA Technical Reports Server (NTRS)

    Guinn, Wiley A.; Rising, Jerry J.; Davis, Walt J.

    1984-01-01

    An advanced PACS control law was developed for a commercial wide-body transport (Lockheed L-1011) by using modern control theory. Validity of the control law was demonstrated by piloted flight simulation tests on the NASA Langley visual motion simulator. The PACS design objective was to develop a PACS that would provide good flying qualities to negative 10 percent static stability margins that were equivalent to those of the baseline aircraft at a 15 percent static stability margin which is normal for the L-1011. Also, the PACS was to compensate for high-Mach/high-g instabilities that degrade flying qualities during upset recoveries and maneuvers. The piloted flight simulation tests showed that the PACS met the design objectives. The simulation demonstrated good flying qualities to negative 20 percent static stability margins for hold, cruise and high-speed flight conditions. Analysis and wind tunnel tests performed on other Lockheed programs indicate that the PACS could be used on an advanced transport configuration to provide a 4 percent fuel savings which results from reduced trim drag by flying at negative static stability margins.

  20. Integrated metrology: an enabler for advanced process control (APC)

    NASA Astrophysics Data System (ADS)

    Schneider, Claus; Pfitzner, Lothar; Ryssel, Heiner

    2001-04-01

    Advanced process control (APC) techniques become more and more important as short innovation cycles in microelectronics and a highly competitive market requires cost-effective solutions in semiconductor manufacturing. APC marks a paradigm shift from statistically based techniques (SPC) using monitor wafers for sampling measurement data towards product wafer control. The APC functionalities including run-to-run control, fault detection, and fault analysis allow to detect process drifts and excursions at an early stage and to minimize the number of misprocessed wafers. APC is being established as part of factory control systems through the definition of an APC framework. A precondition for APC is the availability of sensors and measurement methods providing the necessary wafer data. This paper discusses integrated metrology as an enabler for APC and demonstrates practical implementations in semiconductor manufacturing.

  1. Ride quality sensitivity to SAS control law and to handling quality variations

    NASA Technical Reports Server (NTRS)

    Roberts, P. A.; Schmidt, D. K.; Swaim, R. L.

    1976-01-01

    The RQ trends which large flexible aircraft exhibit under various parameterizations of control laws and handling qualities are discussed. A summary of the assumptions and solution technique, a control law parameterization review, a discussion of ride sensitivity to handling qualities, and the RQ effects generated by implementing relaxed static stability configurations are included.

  2. Refinements and Tests of an Advanced Controller to Mitigate Fatigue Loads in the Controls Advanced Research Turbine: Preprint

    SciTech Connect

    Wright, A.; Fleming, P.

    2010-12-01

    Wind turbines are complex, nonlinear, dynamic systems forced by aerodynamic, gravitational, centrifugal, and gyroscopic loads. The aerodynamics of wind turbines are nonlinear, unsteady, and complex. Turbine rotors are subjected to a complicated 3-D turbulent wind inflow field, with imbedded coherent vortices that drive fatigue loads and reduce lifetime. Design of control algorithms for wind turbines must account for multiple control objectives. Future large multi-megawatt turbines must be designed with lighter weight structures, using active controls to mitigate fatigue loads, while maximizing energy capture. Active damping should be added to these dynamic structures to maintain stability for operation in a complex environment. At the National Renewable Energy Laboratory (NREL), we have designed, implemented, and tested advanced controls to maximize energy extraction and reduce structural dynamic loads. These control designs are based on linear models of the turbine that are generated by specialized modeling software. In this paper, we present field test results of an advanced control algorithm to mitigate blade, tower, and drivetrain loads in Region 3.

  3. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    SciTech Connect

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  4. Supplemental Control for Aircraft Riding Qualities

    NASA Technical Reports Server (NTRS)

    Williams, Rolanda S.; Ashokkumar, C. R.; Homaifar, Abdollah

    1997-01-01

    The concept of preview control has been applied and proven to be successful in the automotive vehicle. These same concepts are now applied to an aircraft under the assumption that exogenous inputs (wind gust, turbulence, etc. ) can be measured. A supplemental control law for surface deflection is designed to compensate for the loss in performance in the presence of atmospheric disturbances. Fuzzy logic control is employed to handle the nonlinear, time varying characteristics of the disturbance. A methodology to tune the outer loop control parameters is presented.

  5. Integration of advanced teleoperation technologies for control of space robots

    NASA Technical Reports Server (NTRS)

    Stagnaro, Michael J.

    1993-01-01

    Teleoperated robots require one or more humans to control actuators, mechanisms, and other robot equipment given feedback from onboard sensors. To accomplish this task, the human or humans require some form of control station. Desirable features of such a control station include operation by a single human, comfort, and natural human interfaces (visual, audio, motion, tactile, etc.). These interfaces should work to maximize performance of the human/robot system by streamlining the link between human brain and robot equipment. This paper describes development of a control station testbed with the characteristics described above. Initially, this testbed will be used to control two teleoperated robots. Features of the robots include anthropomorphic mechanisms, slaving to the testbed, and delivery of sensory feedback to the testbed. The testbed will make use of technologies such as helmet mounted displays, voice recognition, and exoskeleton masters. It will allow tor integration and testing of emerging telepresence technologies along with techniques for coping with control link time delays. Systems developed from this testbed could be applied to ground control of space based robots. During man-tended operations, the Space Station Freedom may benefit from ground control of IVA or EVA robots with science or maintenance tasks. Planetary exploration may also find advanced teleoperation systems to be very useful.

  6. Artificial Intelligent Control for a Novel Advanced Microwave Biodiesel Reactor

    NASA Astrophysics Data System (ADS)

    Wali, W. A.; Hassan, K. H.; Cullen, J. D.; Al-Shamma'a, A. I.; Shaw, A.; Wylie, S. R.

    2011-08-01

    Biodiesel, an alternative diesel fuel made from a renewable source, is produced by the transesterification of vegetable oil or fat with methanol or ethanol. In order to control and monitor the progress of this chemical reaction with complex and highly nonlinear dynamics, the controller must be able to overcome the challenges due to the difficulty in obtaining a mathematical model, as there are many uncertain factors and disturbances during the actual operation of biodiesel reactors. Classical controllers show significant difficulties when trying to control the system automatically. In this paper we propose a comparison of artificial intelligent controllers, Fuzzy logic and Adaptive Neuro-Fuzzy Inference System(ANFIS) for real time control of a novel advanced biodiesel microwave reactor for biodiesel production from waste cooking oil. Fuzzy logic can incorporate expert human judgment to define the system variables and their relationships which cannot be defined by mathematical relationships. The Neuro-fuzzy system consists of components of a fuzzy system except that computations at each stage are performed by a layer of hidden neurons and the neural network's learning capability is provided to enhance the system knowledge. The controllers are used to automatically and continuously adjust the applied power supplied to the microwave reactor under different perturbations. A Labview based software tool will be presented that is used for measurement and control of the full system, with real time monitoring.

  7. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SO2 monitoring system shall be considered out-of-control. The length of the out-of-control period..., non-quality-assured data for each disapproved system. (2) Out-of-control period. Whenever a continuous... other audit, the system is out-of-control. The owner or operator shall follow the procedures for...

  8. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SO2 monitoring system shall be considered out-of-control. The length of the out-of-control period..., non-quality-assured data for each disapproved system. (2) Out-of-control period. Whenever a continuous... other audit, the system is out-of-control. The owner or operator shall follow the procedures for...

  9. The patient perspective: Quality of life in advanced heart failure with frequent hospitalisations.

    PubMed

    Nieminen, Markku S; Dickstein, Kenneth; Fonseca, Cândida; Serrano, Jose Magaña; Parissis, John; Fedele, Francesco; Wikström, Gerhard; Agostoni, Piergiuseppe; Atar, Shaul; Baholli, Loant; Brito, Dulce; Colet, Josep Comín; Édes, István; Gómez Mesa, Juan E; Gorjup, Vojka; Garza, Eduardo Herrera; González Juanatey, José R; Karanovic, Nenad; Karavidas, Apostolos; Katsytadze, Igor; Kivikko, Matti; Matskeplishvili, Simon; Merkely, Béla; Morandi, Fabrizio; Novoa, Angel; Oliva, Fabrizio; Ostadal, Petr; Pereira-Barretto, Antonio; Pollesello, Piero; Rudiger, Alain; Schwinger, Robert H G; Wieser, Manfred; Yavelov, Igor; Zymliński, Robert

    2015-07-15

    End of life is an unfortunate but inevitable phase of the heart failure patients' journey. It is often preceded by a stage in the progression of heart failure defined as advanced heart failure, and characterised by poor quality of life and frequent hospitalisations. In clinical practice, the efficacy of treatments for advanced heart failure is often assessed by parameters such as clinical status, haemodynamics, neurohormonal status, and echo/MRI indices. From the patients' perspective, however, quality-of-life-related parameters, such as functional capacity, exercise performance, psychological status, and frequency of re-hospitalisations, are more significant. The effects of therapies and interventions on these parameters are, however, underrepresented in clinical trials targeted to assess advanced heart failure treatment efficacy, and data are overall scarce. This is possibly due to a non-universal definition of the quality-of-life-related endpoints, and to the difficult standardisation of the data collection. These uncertainties also lead to difficulties in handling trade-off decisions between quality of life and survival by patients, families and healthcare providers. A panel of 34 experts in the field of cardiology and intensive cardiac care from 21 countries around the world convened for reviewing the existing data on quality-of-life in patients with advanced heart failure, discussing and reaching a consensus on the validity and significance of quality-of-life assessment methods. Gaps in routine care and research, which should be addressed, were identified. Finally, published data on the effects of current i.v. vasoactive therapies such as inotropes, inodilators, and vasodilators on quality-of-life in advanced heart failure patients were analysed. PMID:25981363

  10. Simulating advanced life support systems to test integrated control approaches

    NASA Astrophysics Data System (ADS)

    Kortenkamp, D.; Bell, S.

    Simulations allow for testing of life support control approaches before hardware is designed and built. Simulations also allow for the safe exploration of alternative control strategies during life support operation. As such, they are an important component of any life support research program and testbed. This paper describes a specific advanced life support simulation being created at NASA Johnson Space Center. It is a discrete-event simulation that is dynamic and stochastic. It simulates all major components of an advanced life support system, including crew (with variable ages, weights and genders), biomass production (with scalable plantings of ten different crops), water recovery, air revitalization, food processing, solid waste recycling and energy production. Each component is modeled as a producer of certain resources and a consumer of certain resources. The control system must monitor (via sensors) and control (via actuators) the flow of resources throughout the system to provide life support functionality. The simulation is written in an object-oriented paradigm that makes it portable, extensible and reconfigurable.

  11. Advanced interactive displays for deployable command and control centers

    NASA Astrophysics Data System (ADS)

    Jedrysik, Peter A.; Parada, Francisco E.; Stedman, Terrance A.; Zhang, Jingyuan

    2003-09-01

    Command and control in today's battlefield environment requires efficient and effective control of massive amounts of constantly changing information from a variety of databases and real-time sensors. Using advanced information technology for presentation and interactive control enables more extensive data fusion and correlation to present an accurate picture of the battlespace to commanders and their staffs. The Interactive DataWall being developed by the Advanced Displays and Intelligent Interfaces (ADII) technology team of the Air Force Research Laboratory's Information Directorate (AFRL/IF) is a strong contender for solving the information management problems facing the 21st century military commander. It provides an ultra high-resolution large screen display with multi-modal, wireless interaction. Commercial off-the-shelf (COTS) technology has been combined with specialized hardware and software developed in-house to provide a unique capability for multimedia data display and control. The technology once isolated to a laboratory environment has been packaged into deployable systems that have been successfully transitioned to support the warfighter in the field.

  12. DIAGNOSTIC EVALUATION OF AIR QUALITY MODELS USING ADVANCED METHODS WITH SPECIALIZED OBSERVATIONS OF SELECTED AMBIENT SPECIES -PART II

    EPA Science Inventory

    This is Part 2 of "Diagnostic Evaluation of Air Quality Models Using Advanced Methods with Specialized Observations of Selected Ambient Species". A limited field campaign to make specialized observations of selected ambient species using advanced and innovative instrumentation f...

  13. Vibroacoustic behavior and noise control studies of advanced composite structures

    NASA Astrophysics Data System (ADS)

    Li, Deyu

    The research presented in this thesis is devoted to the problems of sound transmission and noise transmission control for advanced composite payload fairings. There are two advanced composite fairings under study. The first is a tapered, cylindrical advanced grid-stiffened composite fairing, and the second is a cylindrical ChamberCore composite fairing. A fully coupled mathematical model for characterizing noise transmission into a finite elastic cylindrical structure with application to the ChamberCore fairing is developed. It combines advantages of wave radiation principles and structural-acoustic modal interaction, and provides an ideal noise transmission model that can be extended to other finite cylindrical structures. Structural-acoustic dynamic parameters of the two fairings are obtained using a combination of numerical, analytical, and experimental approaches. An in-situ method for experimentally characterizing sound transmission into the fairings called noise reduction spectrum (NRS) is developed based on noise reduction. The regions of interest in the NRS curves are identified and verified during a passive control investigation, where various fill materials are added into wall-chambers of the ChamberCore fairing. Both Helmholtz resonators (HRs) and long T-shaped acoustic resonators (ARs) are also used to successfully control noise transmission into the ChamberCore fairing. In the process, an accurate model for the resonant frequency calculation and design of cylindrical HRs is derived. Further, a novel and more general model for the design of multi-modal, long, T-shaped ARs is developed, including three new end-correction equations that are validated experimentally. The control results show that noise attenuation is significant in the controlled modes, and the control is also observed in some modes that are not targeted, due to acoustic modal coupling via the structure. Helmholtz resonators are found to produce between 2.0 and 7.7 dB increase in NRS in

  14. Fiber optic (flight quality) sensors for advanced aircraft propulsion

    NASA Technical Reports Server (NTRS)

    Poppel, Gary L.

    1994-01-01

    Development of flight prototype, fiber-optic sensing system components for measuring nine sensed parameters (three temperatures, two speeds, three positions, and one flame) on an F404-400 aircraft engine is described. Details of each sensor's design, functionality, and environmental testing, and the electro-optics architecture for sensor signal conditioning are presented. Eight different optical sensing techniques were utilized. Design, assembly, and environmental testing of an engine-mounted, electro-optics chassis unit (EOU), providing MIL-C-1553 data output, are related. Interconnection cables and connectors between the EOU and the sensors are identified. Results of sensor/cable/circuitry integrated testing, and installation and ground testing of the sensor system on an engine in October 1993 and April 1994 are given, including comparisons with the engine control system's electrical sensors. Lessons learned about the design, fabrication, testing, and integration of the sensor system components are included.

  15. DTIPrep: quality control of diffusion-weighted images.

    PubMed

    Oguz, Ipek; Farzinfar, Mahshid; Matsui, Joy; Budin, Francois; Liu, Zhexing; Gerig, Guido; Johnson, Hans J; Styner, Martin

    2014-01-01

    In the last decade, diffusion MRI (dMRI) studies of the human and animal brain have been used to investigate a multitude of pathologies and drug-related effects in neuroscience research. Study after study identifies white matter (WM) degeneration as a crucial biomarker for all these diseases. The tool of choice for studying WM is dMRI. However, dMRI has inherently low signal-to-noise ratio and its acquisition requires a relatively long scan time; in fact, the high loads required occasionally stress scanner hardware past the point of physical failure. As a result, many types of artifacts implicate the quality of diffusion imagery. Using these complex scans containing artifacts without quality control (QC) can result in considerable error and bias in the subsequent analysis, negatively affecting the results of research studies using them. However, dMRI QC remains an under-recognized issue in the dMRI community as there are no user-friendly tools commonly available to comprehensively address the issue of dMRI QC. As a result, current dMRI studies often perform a poor job at dMRI QC. Thorough QC of dMRI will reduce measurement noise and improve reproducibility, and sensitivity in neuroimaging studies; this will allow researchers to more fully exploit the power of the dMRI technique and will ultimately advance neuroscience. Therefore, in this manuscript, we present our open-source software, DTIPrep, as a unified, user friendly platform for thorough QC of dMRI data. These include artifacts caused by eddy-currents, head motion, bed vibration and pulsation, venetian blind artifacts, as well as slice-wise and gradient-wise intensity inconsistencies. This paper summarizes a basic set of features of DTIPrep described earlier and focuses on newly added capabilities related to directional artifacts and bias analysis. PMID:24523693

  16. DTIPrep: quality control of diffusion-weighted images

    PubMed Central

    Oguz, Ipek; Farzinfar, Mahshid; Matsui, Joy; Budin, Francois; Liu, Zhexing; Gerig, Guido; Johnson, Hans J.; Styner, Martin

    2014-01-01

    In the last decade, diffusion MRI (dMRI) studies of the human and animal brain have been used to investigate a multitude of pathologies and drug-related effects in neuroscience research. Study after study identifies white matter (WM) degeneration as a crucial biomarker for all these diseases. The tool of choice for studying WM is dMRI. However, dMRI has inherently low signal-to-noise ratio and its acquisition requires a relatively long scan time; in fact, the high loads required occasionally stress scanner hardware past the point of physical failure. As a result, many types of artifacts implicate the quality of diffusion imagery. Using these complex scans containing artifacts without quality control (QC) can result in considerable error and bias in the subsequent analysis, negatively affecting the results of research studies using them. However, dMRI QC remains an under-recognized issue in the dMRI community as there are no user-friendly tools commonly available to comprehensively address the issue of dMRI QC. As a result, current dMRI studies often perform a poor job at dMRI QC. Thorough QC of dMRI will reduce measurement noise and improve reproducibility, and sensitivity in neuroimaging studies; this will allow researchers to more fully exploit the power of the dMRI technique and will ultimately advance neuroscience. Therefore, in this manuscript, we present our open-source software, DTIPrep, as a unified, user friendly platform for thorough QC of dMRI data. These include artifacts caused by eddy-currents, head motion, bed vibration and pulsation, venetian blind artifacts, as well as slice-wise and gradient-wise intensity inconsistencies. This paper summarizes a basic set of features of DTIPrep described earlier and focuses on newly added capabilities related to directional artifacts and bias analysis. PMID:24523693

  17. Emerging technology: A key enabler for modernizing pharmaceutical manufacturing and advancing product quality.

    PubMed

    O'Connor, Thomas F; Yu, Lawrence X; Lee, Sau L

    2016-07-25

    Issues in product quality have produced recalls and caused drug shortages in United States (U.S.) in the past few years. These quality issues were often due to outdated manufacturing technologies and equipment as well as lack of an effective quality management system. To ensure consistent supply of safe, effective and high-quality drug products available to the patients, the U.S. Food and Drug Administration (FDA) supports modernizing pharmaceutical manufacturing for improvements in product quality. Specifically, five new initiatives are proposed here to achieve this goal. They include: (i) advancing regulatory science for pharmaceutical manufacturing; (ii) establishing a public-private institute for pharmaceutical manufacturing innovation; (iii) creating incentives for investment in the technological upgrade of manufacturing processes and facilities; (iv) leveraging external expertise for regulatory quality assessment of emerging technologies; and (v) promoting the international harmonization of approaches for expediting the global adoption of emerging technologies. PMID:27260134

  18. Illumina human exome genotyping array clustering and quality control

    PubMed Central

    Guo, Yan; He, Jing; Zhao, Shilin; Wu, Hui; Zhong, Xue; Sheng, Quanhu; Samuels, David C; Shyr, Yu; Long, Jirong

    2015-01-01

    With the rise of high-throughput sequencing technology, traditional genotyping arrays are gradually being replaced by sequencing technology. Against this trend, Illumina has introduced an exome genotyping array that provides an alternative approach to sequencing, especially suited to large-scale genome-wide association studies (GWASs). the exome genotyping array targets the exome plus rare single-nucleotide polymorphisms (SNPs), a feature that makes it substantially more challenging to process than previous genotyping arrays that targeted common SNPs. Researchers have struggled to generate a reliable protocol for processing exome genotyping array data. The Vanderbilt epidemiology center, in cooperation with Vanderbilt Technologies for Advanced Genomics Analysis and Research Design (VANGARD), has developed a thorough exome chip–processing protocol. The protocol was developed during the processing of several large exome genotyping array-based studies, which included over 60,000 participants combined. The protocol described herein contains detailed clustering techniques and robust quality control procedures, and it can benefit future exome genotyping array–based GWASs. PMID:25321409

  19. Mieap suppresses murine intestinal tumor via its mitochondrial quality control

    PubMed Central

    Tsuneki, Masayuki; Nakamura, Yasuyuki; Kinjo, Takao; Nakanishi, Ruri; Arakawa, Hirofumi

    2015-01-01

    Mieap, a novel p53-inducible protein, plays a key role in maintaining healthy mitochondria in various pathophysiological states. Here, we show that Mieap deficiency in ApcMin/+ mice is strikingly associated with the malignant progression of murine intestinal tumors. To understand the role that Mieap plays in in vivo tumorigenesis, we generated Mieap heterozygous (ApcMin/+ Mieap+/−) and homozygous (ApcMin/+ Mieap−/−) ApcMin/+ mice. Interestingly, the ApcMin/+ mice with the Mieap+/− and Mieap−/− genetic background revealed remarkable shortening of the lifetime compared to ApcMin/+ mice because of severe anemia. A substantial increase in the number and size of intestinal polyps was associated with Mieap gene deficiency. Histopathologically, intestinal tumors in the Mieap-deficient ApcMin/+ mice clearly demonstrated advanced grades of adenomas and adenocarcinomas. We demonstrated that the significant increase in morphologically unhealthy mitochondria and trace accumulations of reactive oxygen species may be mechanisms underlying the increased malignant progression of the intestinal tumors of Mieap-deficient ApcMin/+ mice. These findings suggest that the Mieap-regulated mitochondrial quality control plays a critical role in preventing mouse intestinal tumorigenesis. PMID:26216032

  20. Mitochondrial Protein Quality Control: The Mechanisms Guarding Mitochondrial Health

    PubMed Central

    Bohovych, Iryna; Chan, Sherine S.L.

    2015-01-01

    Abstract Significance: Mitochondria are complex dynamic organelles pivotal for cellular physiology and human health. Failure to maintain mitochondrial health leads to numerous maladies that include late-onset neurodegenerative diseases and cardiovascular disorders. Furthermore, a decline in mitochondrial health is prevalent with aging. A set of evolutionary conserved mechanisms known as mitochondrial quality control (MQC) is involved in recognition and correction of the mitochondrial proteome. Recent Advances: Here, we review current knowledge and latest developments in MQC. We particularly focus on the proteolytic aspect of MQC and its impact on health and aging. Critical Issues: While our knowledge about MQC is steadily growing, critical gaps remain in the mechanistic understanding of how MQC modules sense damage and preserve mitochondrial welfare, particularly in higher organisms. Future Directions: Delineating how coordinated action of the MQC modules orchestrates physiological responses on both organellar and cellular levels will further elucidate the current picture of MQC's role and function in health, cellular stress, and degenerative diseases. Antioxid. Redox Signal. 22, 977–994. PMID:25546710

  1. Control system for insertion devices at the advanced photon source

    SciTech Connect

    Makarov, Oleg A.; Den Hartog, Patric; Moog, Elizabeth R.; Smith, Martin L.

    1997-07-01

    Eighteen insertion devices (IDs) are installed at the Advanced Photon Source (APS), and three more are scheduled for installation by the end of this year. A distributed control system for insertion devices at the APS storage ring was created with the Experimental Physics and Industrial Control System (EPICS). The basic components of this system are operator interfaces (OPIs), input output controllers (IOCs), and a local area network that allows the OPI and IOC to communicate. The IOC operates under the VxWorks OS with an EPICS database and a sequencer. The sequencer runs an ID control program written in State Notation Language. The OPI is built with the EPICS tool MEDM and provides display screens with input and output fields and buttons for gap control of the IDs. Global commands like 'open all IDs' are C-shell scripts invoked from the display menu. The algorithms for control and protection of the ID and ID vacuum chamber and the accuracy of gap control are discussed.

  2. Control system for insertion devices at the Advanced Photon Source

    SciTech Connect

    Makarov, O.A.; Den Hartog, P.; Moog, E.R.; Smith, M.L.

    1997-09-01

    Eighteen insertion devices (IDs) are installed at the Advanced Photon Source (APS), and three more are scheduled for installation by the end of this year. A distributed control system for insertion devices at the APS storage ring was created with the Experimental Physics and Industrial Control System (EPICS). The basic components of this system are operator interfaces (OPIs), input output controllers (IOCs), and a local area network that allows the OPI and IOC to communicate. The IOC operates under the VxWorks OS with an EPICS database and a sequencer. The sequencer runs an ID control program written in State Notation Language. The OPI is built with the EPICS tool MEDM and provides display screens with input and output fields and buttons for gap control of the IDs. Global commands like ``open all IDs`` are C-shell scripts invoked from the display menu. The algorithms for control and protection of the ID and ID vacuum chamber and the accuracy of gap control are discussed.

  3. Control system for insertion devices at the advanced photon source

    SciTech Connect

    Makarov, O.A.; Den Hartog, P.; Moog, E.R.; Smith, M.L.

    1997-07-01

    Eighteen insertion devices (IDs) are installed at the Advanced Photon Source (APS), and three more are scheduled for installation by the end of this year. A distributed control system for insertion devices at the APS storage ring was created with the Experimental Physics and Industrial Control System (EPICS). The basic components of this system are operator interfaces (OPIs), input output controllers (IOCs), and a local area network that allows the OPI and IOC to communicate. The IOC operates under the VxWorks OS with an EPICS database and a sequencer. The sequencer runs an ID control program written in State Notation Language. The OPI is built with the EPICS tool MEDM and provides display screens with input and output fields and buttons for gap control of the IDs. Global commands like {open_quotes}open all IDs{close_quotes} are C-shell scripts invoked from the display menu. The algorithms for control and protection of the ID and ID vacuum chamber and the accuracy of gap control are discussed. {copyright} {ital 1997 American Institute of Physics.}

  4. Reviewing the impact of advanced control room technology

    SciTech Connect

    Wilhelmsen, C.A.; Gertman, D.I.; Ostrom, L.T.; Nelson, W.R.; Galyean, W.J.; Byers, J.C.

    1992-08-01

    Progress to date on assessing the nature of the expected changes in human performance and risk associated with the introduction of digital control, instrumentation, and display systems is presented. Expected changes include the shift toward more supervisory tasks, development of intervention strategies, and reallocation of function between human and machine. Results are reported in terms of the scope of new technology, human performance issues, and crews experience with digital control systems in a variety of industries petrochemical and aerospace. Plans to conduct a limited Probabilistic Risk Assessment/Human Reliability Assessment (PRA/HRA) comparison between a conventional NUREG-1150 series plant and that same plant retrofit with distributed control and advanced instrumentation and display are also presented. Changes needed to supplement existing HRA modeling methods and quantification techniques are discussed.

  5. Reviewing the impact of advanced control room technology

    SciTech Connect

    Wilhelmsen, C.A.; Gertman, D.I.; Ostrom, L.T.; Nelson, W.R.; Galyean, W.J.; Byers, J.C.

    1992-01-01

    Progress to date on assessing the nature of the expected changes in human performance and risk associated with the introduction of digital control, instrumentation, and display systems is presented. Expected changes include the shift toward more supervisory tasks, development of intervention strategies, and reallocation of function between human and machine. Results are reported in terms of the scope of new technology, human performance issues, and crews experience with digital control systems in a variety of industries petrochemical and aerospace. Plans to conduct a limited Probabilistic Risk Assessment/Human Reliability Assessment (PRA/HRA) comparison between a conventional NUREG-1150 series plant and that same plant retrofit with distributed control and advanced instrumentation and display are also presented. Changes needed to supplement existing HRA modeling methods and quantification techniques are discussed.

  6. Status and design of the Advanced Photon Source control system

    SciTech Connect

    McDowell, W.; Knott, M.; Lenkszus, F.; Kraimer, M.; Arnold, N.; Daly, R.

    1993-06-01

    This paper presents the current status of the Advanced Photon Source (APS) control system. It will discuss the design decisions which led us to use industrial standards and collaborations with other laboratories to develop the APS control system. The system uses high performance graphic workstations and the X-windows Graphical User Interface (GUI) at the operator interface level. It connects to VME/VXI-based microprocessors at the field level using TCP/IP protocols over high performance networks. This strategy assures the flexibility and expansibility of the control system. A defined interface between the system components will allow the system to evolve with the direct addition of future, improved equipment and new capabilities.

  7. Status and design of the Advanced Photon Source control system

    SciTech Connect

    McDowell, W.; Knott, M.; Lenkszus, F.; Kraimer, M.; Arnold, N.; Daly, R.

    1993-01-01

    This paper presents the current status of the Advanced Photon Source (APS) control system. It will discuss the design decisions which led us to use industrial standards and collaborations with other laboratories to develop the APS control system. The system uses high performance graphic workstations and the X-windows Graphical User Interface (GUI) at the operator interface level. It connects to VME/VXI-based microprocessors at the field level using TCP/IP protocols over high performance networks. This strategy assures the flexibility and expansibility of the control system. A defined interface between the system components will allow the system to evolve with the direct addition of future, improved equipment and new capabilities.

  8. Advancing Product Quality: a Summary of the Inaugural FDA/PQRI Conference.

    PubMed

    Yu, Lawrence X; Baker, Jeffrey; Berlam, Susan C; Boam, Ashley; Brandreth, E J; Buhse, Lucinda; Cosgrove, Thomas; Doleski, David; Ensor, Lynne; Famulare, Joseph; Ganapathy, Mohan; Grampp, Gustavo; Hussong, David; Iser, Robert; Johnston, Gordon; Kesisoglou, Filippos; Khan, Mansoor; Kozlowski, Steven; Lacana, Emanuela; Lee, Sau L; Miller, Stephen; Miksinski, Sarah Pope; Moore, Christine M V; Mullin, Theresa; Raju, G K; Raw, Andre; Rosencrance, Susan; Rosolowsky, Mark; Stinavage, Paul; Thomas, Hayden; Wesdyk, Russell; Windisch, Joerg; Vaithiyalingam, Sivakumar

    2015-07-01

    On September 16 and 17, 2014, the Food and Drug Administration (FDA) and Product Quality Research Institute (PQRI) inaugurated their Conference on Evolving Product Quality. The Conference is conceived as an annual forum in which scientists from regulatory agencies, industry, and academia may exchange viewpoints and work together to advance pharmaceutical quality. This Conference Summary Report highlights key topics of this conference, including (1) risk-based approaches to pharmaceutical development, manufacturing, regulatory assessment, and post-approval changes; (2) FDA-proposed quality metrics for products, facilities, and quality management systems; (3) performance-based quality assessment and clinically relevant specifications; (4) recent developments and implementation of continuous manufacturing processes, question-based review, and European Medicines Agency (EMA)-FDA pilot for Quality-by-Design (QbD) applications; and (5) breakthrough therapies, biosimilars, and international harmonization, focusing on ICH M7 and Q3D guidelines. The second FDA/PQRI conference on advancing product quality is planned for October 5-7, 2015. PMID:25840884

  9. Advanced Guidance and Control Project for Reusable Launch Vehicles

    NASA Technical Reports Server (NTRS)

    Hanson, John M.

    2000-01-01

    The goals of this project are to significantly reduce the time and cost associated with guidance and control design for reusable launch vehicles, and to increase their safety and reliability. Success will lead to reduced cycle times during vehicle design and to reduced costs associated with flying to new orbits, with new payloads, and with modified vehicles. Success will also lead to more robustness to unforeseen circumstances in flight thereby enhancing safety and reducing risk. There are many guidance and control methods available that hold some promise for improvement in the desired areas. Investigators are developing a representative set of independent guidance and control methods for this project. These methods are being incorporated into a high-fidelity off is being conducted across a broad range of flight requirements. The guidance and control methods that perform the best will have demonstrated the desired qualities.

  10. Statistical process control for total quality

    NASA Astrophysics Data System (ADS)

    Ali, Syed W.

    1992-06-01

    The paper explains the techniques and applications of statistical process control (SPC). Examples of control charts used in the Poseidon program of the NASA ocean topography experiment (TOPEX) and a brief discussion of Taguchi methods are presented. It is noted that SPC involves everyone in process improvement by providing objective, workable data. It permits continuous improvement instead of merely aiming for all parts to be within a tolerance band.

  11. Web quality control for lectures: Supercourse and Amazon.com.

    PubMed

    Linkov, Faina; LaPorte, Ronald; Lovalekar, Mita; Dodani, Sunita

    2005-12-01

    Peer review has been at the corner stone of quality control of the biomedical journals in the past 300 years. With the emergency of the Internet, new models of quality control and peer review are emerging. However, such models are poorly investigated. We would argue that the popular system of quality control used in Amazon.com offers a way to ensure continuous quality improvement in the area of research communications on the Internet. Such system is providing an interesting alternative to the traditional peer review approaches used in the biomedical journals and challenges the traditional paradigms of scientific publishing. This idea is being explored in the context of Supercourse, a library of 2,350 prevention lectures, shared for free by faculty members from over 150 countries. Supercourse is successfully utilizing quality control approaches that are similar to Amazon.com model. Clearly, the existing approaches and emerging alternatives for quality control in scientific communications needs to be assessed scientifically. Rapid explosion of internet technologies could be leveraged to produce better, more cost effective systems for quality control in the biomedical publications and across all sciences. PMID:16342339

  12. Achieving indoor air quality through contaminant control

    SciTech Connect

    Katzel, J.

    1995-07-10

    Federal laws outlining industry`s responsibilities in creating a healthy, hazard-free workspace are well known. OSHA`s laws on interior air pollution establish threshold limit values (TLVs) and permissible exposure limits (PELs) for more than 500 potentially hazardous substances found in manufacturing operations. Until now, OSHA has promulgated regulations only for the manufacturing environment. However, its recently-proposed indoor air quality (IAQ) ruling, if implemented, will apply to all workspaces. It regulates IAQ, including environmental tobacco smoke, and requires employers to write and implement IAQ compliance plans.

  13. Quality Control of Fungal and Viral Biocontrol Agents

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Constraints to the use of the “inundative” or “biopesticide” strategy of biological control include a lack of consistent pest control efficacy, short product shelf-life, and costly production and stabilization processes. Quality control measures that standardize the production, stabilization, formu...

  14. Advanced control strategy for plant heat rate improvement

    SciTech Connect

    Schultz, P.; Frerichs, D.K.; Kyr, D.

    1995-12-31

    Florida Power & Light Company (FPL) supplies electricity to about half of the population of Florida, roughly 6.5 million people. The load base is largely residential/business with the obvious seasonal extremes due to the climate. FPL`s generating capacity is 16,320 MW composed of 70% traditional fossil cycle, 18% nuclear, and 12% gas turbine. The system load profile coupled with bulk power purchases is such that the 400 MW class units (9 Foster Wheeler drum type units comprising 24% of total capacity) are now forced to cycle daily all year, and to come off line on weekends during the winter months. The current economic realities of power generation force utility companies to seek methods to improve plant heat rate, and FPL is no exception. FPL believed it possible to achieve the goal of lower heat rate and follow the required load demand with the 400 MW class units through the use of an advanced control strategy implemented totally within the unit`s Distributed Control System (DCS). As of the writing of this paper, the project is still ongoing. This paper will present the theory and methodology of the advanced control strategy along with the current design and implementation status and results obtained to date.

  15. Mesh quality control for multiply-refined tetrahedral grids

    NASA Technical Reports Server (NTRS)

    Biswas, Rupak; Strawn, Roger

    1994-01-01

    A new algorithm for controlling the quality of multiply-refined tetrahedral meshes is presented in this paper. The basic dynamic mesh adaption procedure allows localized grid refinement and coarsening to efficiently capture aerodynamic flow features in computational fluid dynamics problems; however, repeated application of the procedure may significantly deteriorate the quality of the mesh. Results presented show the effectiveness of this mesh quality algorithm and its potential in the area of helicopter aerodynamics and acoustics.

  16. Advanced Transport Operating System (ATOPS) control display unit software description

    NASA Technical Reports Server (NTRS)

    Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

    1992-01-01

    The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

  17. New virtual laboratories presenting advanced motion control concepts

    NASA Astrophysics Data System (ADS)

    Goubej, Martin; Krejčí, Alois; Reitinger, Jan

    2015-11-01

    The paper deals with development of software framework for rapid generation of remote virtual laboratories. Client-server architecture is chosen in order to employ real-time simulation core which is running on a dedicated server. Ordinary web browser is used as a final renderer to achieve hardware independent solution which can be run on different target platforms including laptops, tablets or mobile phones. The provided toolchain allows automatic generation of the virtual laboratory source code from the configuration file created in the open- source Inkscape graphic editor. Three virtual laboratories presenting advanced motion control algorithms have been developed showing the applicability of the proposed approach.

  18. Ultrasonic Testing, Aviation Quality Control (Advanced): 9227.03.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    This unit of instruction covers the theory of ultrasonic sound, methods of applying soundwaves to test specimens and interpreting results, calibrating the ultrasonic equipment, and the use of standards. Study periods, group discussions, and extensive use of textbooks and training manuals are to be used. These are listed along with references and…

  19. SECOND GENERATION ADVANCED REBURNING FOR HIGH EFFICIENCY NOx CONTROL

    SciTech Connect

    1998-07-30

    This project is designed to develop a family of novel NO{sub x} control technologies, called Second Generation Advanced Reburning which has the potential to achieve 90+% NO{sub x} control in coal fired boilers at a significantly lower cost than SCR. The third reporting period in Phase II (April 1--June 30, 1998) included experimental activities at pilot scale and comparison of the results with full-scale data. The pilot scale tests were performed with the objective of simulating furnace conditions of ongoing full-scale tests at the Greenidge boiler No. 6 owned and operated by NYSEG and defining the processes controlling AR performance to subsequently improve the performance. The tests were conducted in EER' s Boiler Simulator Facility. The main fuel pulsing system was used at the BSF to control the degree of unmixedness, thus providing control over furnace gas O{sub 2} and CO concentrations. Results on AR-Lean, presented in the previous quarterly report, were compared with full-scale data. Performance of reburn+SNCR was tested to predict NO{sub x} control at Greenidge. The results of the BSF reburn+SNCR simulation tests demonstrated that there are synergistic advantages of using these two technologies in series. In particular, injection of overfire air provides additional mixing that reduces negative effects on AR performance at the temperature regime of the Greenidge boiler.

  20. Indicator system for advanced nuclear plant control complex

    DOEpatents

    Scarola, Kenneth; Jamison, David S.; Manazir, Richard M.; Rescorl, Robert L.; Harmon, Daryl L.

    1993-01-01

    An advanced control room complex for a nuclear power plant, including a discrete indicator and alarm system (72) which is nuclear qualified for rapid response to changes in plant parameters and a component control system (64) which together provide a discrete monitoring and control capability at a panel (14-22, 26, 28) in the control room (10). A separate data processing system (70), which need not be nuclear qualified, provides integrated and overview information to the control room and to each panel, through CRTs (84) and a large, overhead integrated process status overview board (24). The discrete indicator and alarm system (72) and the data processing system (70) receive inputs from common plant sensors and validate the sensor outputs to arrive at a representative value of the parameter for use by the operator during both normal and accident conditions, thereby avoiding the need for him to assimilate data from each sensor individually. The integrated process status board (24) is at the apex of an information hierarchy that extends through four levels and provides access at each panel to the full display hierarchy. The control room panels are preferably of a modular construction, permitting the definition of inputs and outputs, the man machine interface, and the plant specific algorithms, to proceed in parallel with the fabrication of the panels, the installation of the equipment and the generic testing thereof.

  1. Academic Quality Control in Nigerian Universities: Exploring Lecturers' Perceptions

    ERIC Educational Resources Information Center

    Obiekezie, E. O.; Ejemot-Nwadiaro, R. I.; Essien, M. I.; Timothy, A. Essien

    2014-01-01

    The level of job performance, international comparability and competitiveness of Nigerian university graduates are burning issues. Consequently, the academic quality of Nigerian universities has come under severe criticism. Since university lecturers are key players in quality control in universities, this study explored their perceptions of…

  2. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28.31 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING...) Each quality control plan shall contain provisions for the management of quality, including: (1... Specification MIL-F-15160D is available for examination at the U.S. Department of Labor, Mine Safety and...

  3. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28.31 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING...) Each quality control plan shall contain provisions for the management of quality, including: (1... Specification MIL-F-15160D is available for examination at the U.S. Department of Labor, Mine Safety and...

  4. 115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770), FACING WEST ON EXTERIOR WALL OF QUALITY ASSURANCE ROOM (106A) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  5. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality...

  6. Evaluation of advanced displays for engine monitoring and control

    NASA Technical Reports Server (NTRS)

    Summers, L. G.

    1993-01-01

    The relative effectiveness of two advanced display concepts for monitoring engine performance for commercial transport aircraft was studied. The concepts were the Engine Monitoring and Control System (EMACS) display developed by NASA Langley and a display by exception design. Both of these concepts were based on the philosophy of providing information that is directly related to the pilot's task. Both concepts used a normalized thrust display. In addition, EMACS used column deviation indicators; i.e., the difference between the actual parameter value and the value predicted by an engine model, for engine health monitoring; while the Display by Exception displayed the engine parameters if the automated system detected a difference between the actual and the predicted values. The results showed that the advanced display concepts had shorter detection and response times. There were no differences in any of the results between manual and auto throttles. There were no effects upon perceived workload or performance on the primary flight task. The majority of pilots preferred the advanced displays and thought they were operationally acceptable. Certification of these concepts depends on the validation of the engine model. Recommendations are made to improve both the EMACS and the display by exception display formats.

  7. A quality control program for waste disposal vault closure

    SciTech Connect

    Benny, H.L.

    1994-07-01

    This paper provides a review of the quality control program employed for closure for a radioactive waste disposal vault at Hanford Washington. The major elements of the program are discussed, as well as the testing results and lessons learned.

  8. Quality control system response to stochastic growth of amyloid fibrils.

    PubMed

    Pigolotti, Simone; Lizana, Ludvig; Otzen, Daniel; Sneppen, Kim

    2013-05-01

    We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. Aggregate growth is contrasted by the cell quality control system, that attacks them at different stages of the growth process, with an efficiency that decreases with their size. Model parameters are estimated from experimental data. Two qualitatively different behaviors emerge: a homeostatic state, where the quality control system is stable and aggregates of large sizes are not formed, and an oscillatory state, where the quality control system periodically breaks down, allowing for formation of large aggregates. We discuss how these periodic breakdowns may constitute a mechanism for the development of neurodegenerative diseases. PMID:23524241

  9. VERIFICATION TESTING OF AIR POLLUTION CONTROL TECHNOLOGY QUALITY MANAGEMENT PLAN

    EPA Science Inventory

    This document is the basis for quality assurance for the Air Pollution Control Technology Verification Center (APCT Center) operated under the U.S. Environmental Protection Agency (EPA). It describes the policies, organizational structure, responsibilities, procedures, and qualit...

  10. 7 CFR 58.733 - Quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be performed in accordance with the appropriate edition of the Official Methods of Analysis of the AOAC as... Cheese Products Bearing USDA Official Identification...

  11. Advancing a New Image of CTE via High-Quality Teacher Preparation

    ERIC Educational Resources Information Center

    Sass, Heather Boggs

    2011-01-01

    There is perhaps no better place to start in advancing a new image of career and technical education (CTE) than by creating the kind of classroom instruction that will prepare students for further learning and the workplace. The quality of teachers and their capacity to construct rich learning experiences for students represents the "front line"…

  12. Mercury Control With The Advanced Hybrid Paticulate Collector

    SciTech Connect

    Stanley J. Miller; Ye Zhuang; Jay Almlie

    2004-09-30

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team included the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC also appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project was to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach included bench-scale batch tests, larger-scale pilot testing with real flue gas on a coal-fired combustion system, and field demonstration at the 2.5-MW scale at a utility power plant to prove scale-up and demonstrate longer-term mercury control. The scope of work was modified to include an additional sixth task, initiated in April 2003. The objective of this task

  13. Mercury Control With The Advanced Hybrid Particulate Collector

    SciTech Connect

    Stanley J. Miller; Ye Zhuang; Jay C. Almlie

    2004-12-31

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory Program Solicitation DE-FC26-01NT41184 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team included the Energy & Environmental Research Center as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC also appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas--solid contactor. The objective of the original five-task project was to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach included benchscale batch tests, larger-scale pilot testing with real flue gas on a coal-fired combustion system, and field demonstration at the 2.5-MW scale at a utility power plant to prove scale-up and demonstrate longer-term mercury control. The scope of work was modified to include an additional sixth task, initiated in April 2003. The objective of this task was to

  14. Progress in Implementing and Testing State-Space Controls for the Controls Advanced Research Turbine: Preprint

    SciTech Connect

    Wright, A. D.; Fingersh, L. J.; Stol, K. A.

    2004-12-01

    Designing wind turbines with maximum energy production and longevity for minimal cost is a major goal of the federal wind program and the wind industry. Control can improve the performance of wind turbines by enhancing energy capture and reducing dynamic loads. At the National Renewable Energy Laboratory (NREL) we are designing state-space control algorithms for turbine speed regulation and load reduction and testing them on the Controls Advanced Research Turbine (CART). The CART is a test-bed especially designed to test advanced control algorithms on a two-bladed teetering hub upwind turbine. In this paper we briefly describe the design of control systems to regulate turbine speed in region 3 for the CART. These controls use rotor collective pitch to regulate speed and also enhance damping in the 1st drive-train torsion, 1st rotor symmetric flap mode, and the 1st tower fore-aft mode. We designed these controls using linear optimal control techniques using state estimation based on limited turbine measurements such as generator speed and tower fore-aft bending moment. In this paper, we describe the issues and steps involved with implementing and testing these controls on the CART, and we show simulated tests to quantify controller performance. We then present preliminary results after implementing and testing these controls on the CART. We compare results from these controls to field test results from a baseline Proportional Integral control system. Finally we report conclusions to this work and outline future studies.

  15. Development of Quality Control Procedures for Lepidoptera

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Lepidopteran species are among the most destructive insect pests throughout the world. The sterile insect technique (SIT), within an area-wide integrated pest management (AW-IPM) approach, has proven to be a valuable tactic for controlling and eradicating important moth pests. Improving laboratory...

  16. Quality Control On Strained Semiconductor Devices

    SciTech Connect

    Dommann, Alex; Neels, Antonia

    2010-11-24

    New semiconductor devices are based very often on strained silicon which promises to squeeze more device performance out of current devices. With strained silicon it is possible to get the same device performance using less power. The technique is using strain as a 'design element' for silicon to improve the device performance and has become a hot topic in semiconductor research in the past years. However in the same time topics like 'System in Package'(SiP) on thin wafers are getting more and more important. The chips of thin wafers in advanced packaging are extremely sensitive to induced stresses due to packaging issues. If we are using now strain as a design element for improving device performance we increase the sensitivity again and therefore also the risk of aging of such SiP's. High Resolution X-ray diffraction (HRXRD) techniques such as Rocking Curves (RC's) and Reciprocal Space Mapping (RSM) are therefore very powerful tools to study the stresses in packaged devices.

  17. Research and development on the application of advanced control technologies to advanced nuclear reactor systems: A US national perspective

    SciTech Connect

    White, J.D.; Monson, L.R.; Carrol, D.G.; Dayal, Y.; Argonne National Lab., IL; General Electric Co., San Jose, CA )

    1989-01-01

    Control system designs for nuclear power plants are becoming more advanced through the use of digital technology and automation. This evolution is taking place because of: (1) the limitations in analog based control system performance and maintenance and availability and (2) the promise of significant improvement in plant operation and availability due to advances in digital and other control technologies. Digital retrofits of control systems in US nuclear plants are occurring now. Designs of control and protection systems for advanced LWRs are based on digital technology. The use of small inexpensive, fast, large-capacity computers in these designs is the first step of an evolutionary process described in this paper. Under the sponsorship of the US Department of Energy (DOE), Oak Ridge National Laboratory, Argonne National Laboratory, GE Nuclear Energy and several universities are performing research and development in the application of advances in control theory, software engineering, advanced computer architectures, artificial intelligence, and man-machine interface analysis to control system design. The target plant concept for the work described in this paper is the Power Reactor Inherently Safe Module reactor (PRISM), an advanced modular liquid metal reactor concept. This and other reactor designs which provide strong passive responses to operational upsets or accidents afford good opportunities to apply these advances in control technology. 18 refs., 5 figs.

  18. Development of electrical feedback controlled heat pipes and the advanced thermal control flight experiment

    NASA Technical Reports Server (NTRS)

    Bienert, W. B.

    1974-01-01

    The development and characteristics of electrical feedback controlled heat pipes (FCHP) are discussed. An analytical model was produced to describe the performance of the FCHP under steady state and transient conditions. An advanced thermal control flight experiment was designed to demonstrate the performance of the thermal control component in a space environment. The thermal control equipment was evaluated on the ATS-F satellite to provide performance data for the components and to act as a thermal control system which can be used to provide temperature stability of spacecraft components in future applications.

  19. Advanced Thermo-Adsorptive Battery: Advanced Thermo-Adsorptive Battery Climate Control System

    SciTech Connect

    2011-12-31

    HEATS Project: MIT is developing a low-cost, compact, high-capacity, advanced thermoadsorptive battery (ATB) for effective climate control of EVs. The ATB provides both heating and cooling by taking advantage of the materials’ ability to adsorb a significant amount of water. This efficient battery system design could offer up as much as a 30% increase in driving range compared to current EV climate control technology. The ATB provides high-capacity thermal storage with little-to-no electrical power consumption. The ATB is also looking to explore the possibility of shifting peak electricity loads for cooling and heating in a variety of other applications, including commercial and residential buildings, data centers, and telecom facilities.

  20. A system concept for an advanced vehicle control system

    SciTech Connect

    Mackey, D.E.; Mackey, W.F. Jr.; Mackey, W.F.

    1996-12-01

    This paper explores a system concept for an Advanced Vehicle Control System (AVCS). The progression of highway design and construction has resulted from an evolution of technologies, inventions, organizational creations, and legislative acts supporting the development of a national interstate transportation system. Until now, highway design and construction has been the domain of civil engineers concerned with highway structures, materials loading, traffic patterns, and supporting facilities. However, the growing need for intelligent vehicle-highway systems (IVHS) requires that traditional civil engineering disciplines be integrated with computers, communications, and eventually fully automated vehicles. This paper`s thesis suggests that the complex highway transportation of the late 20th century and the 21st century can benefit from the collaboration of systems engineers and civil engineers. This paper identifies and prototypes an AVCS concept with roadside computers controlling the lateral and longitudinal movements of a vehicle.

  1. Second Generation Advanced Reburning for High Efficiency NOx Control

    SciTech Connect

    Vladimir M. Zamansky; Vitali V. Lissianski

    1999-12-31

    This project is designed to develop a family of novel NO{sub x} control technologies, called Second Generation Advanced Reburning (SGAR) which has the potential to achieve 90+ NO{sub x} control in coal fired boilers at a significantly lower cost than Selective Catalytic Reduction. The ninth reporting period in Phase II (October 1-December 31, 1999) included preparation of the 10 x 10{sup 6} Btu/hr Tower Furnace for tests and setting the SGAR model to predict process performance under Tower Furnace conditions. Based on results of previous work, a paper has been prepared and submitted for the presentation at the 28 Symposium (International) on Combustion to be held at the University of Edinburgh, Scotland.

  2. Advanced optical and thermal technologies for aperture control

    SciTech Connect

    Selkowitz, S.E.; Lampert, C.M.; Rubin, M.

    1982-09-01

    Control of heat transfer and radiant energy flow through building apertures is essential for maximizing thermal and daylighting benefits and minimizing undesired heating and cooling loads. Architectural solutions based on current technology generally add devices such as louvers, shutters, shades, or blinds to the glazing system. The objectives and initial accomplishments of a research program the goal of which is to identify and evaluate advanced optical and thermal technologies for controlling aperture energy flows, thus reducing building energy requirements are outlined. Activities are described in four program areas: (1) low-conductance, high-transmittance glazing materials (e.g., heat mirrors, aerogels); (2) optical switching materials (e.g., electrochromic, photochromic); (3) selective transmitters; and (4) daylight enhancement techniques.

  3. Advanced optical and thermal technologies for aperture control

    SciTech Connect

    Selkowitz, S.E.; Lampert, C.M.; Rubin, M.

    1983-11-01

    Control of heat transfer and radiant energy flow through building apertures is essential for maximizing thermal and daylighting benefits and minimizing undesired heating and cooling loads. Architectural solutions based on current technology generally add devices such as louvers, shutters, shades, or blinds to the glazing system. The objectives and initial accomplishments of a research program are outlined, the goal of which is to identify and evaluate advanced optical and thermal technologies for controlling aperture energy flows, thus reducing building energy requirements. Activities in four program areas are described: (1) low-conductance, high-transmittance glazing materials (e.g., heat mirrors, aerogels) (2) optical switching materials (e.g., electrochromic, photochromic) (3) selective transmitters and (4) daylight enhancement techniques.

  4. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    SciTech Connect

    Stanley J. Miller; Ye Zhuang; Michelle R. Olderbak

    2003-03-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4--Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  5. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    SciTech Connect

    Ye Zhuang; Stanley J. Miller; Steven A. Benson; Michelle R. Olderbak

    2003-08-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the ''Advanced Hybrid''{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultra-high collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  6. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    SciTech Connect

    Stanley J. Miller; Ye Zhuang; Michelle R. Olderbak

    2002-11-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Power Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the ADVANCED HYBRID{trademark} Filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  7. Mercuty Control With The Advanced Hybrid Particulate Collector

    SciTech Connect

    Ye Zhuang; Stanley J. Miller; Michelle R. Olderbak

    2003-03-31

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  8. An Advanced Tool for Control System Design and Maintenance

    SciTech Connect

    Storm, Joachim; Lohmann, Heinz

    2006-07-01

    The detailed engineering for control systems is usually supported by CAD Tools creating the relevant logic diagrams including software parameters and signal cross references. However at this stage of the design an early V and V process for checking out the functional correctness of the design is not available. The article describes the scope and capabilities of an advanced control system design tool which has the embedded capability of a stand-alone simulation of complex logic structures. The tool provides the following features for constructing logic diagrams for control systems: - Drag and Drop construction of logic diagrams using a predefined symbol sets; - Cross reference facility; - Data extraction facility; - Stand-alone simulation for Logic Diagrams featuring: On the fly changes, signal line animation, value boxes and mini trends etc. - Creation and on-line animation of Compound Objects (Handler); - Code Generation Facility for Simulation; - Code Generation Facility for several control systems. The results of the integrated simulation based V and V process can be used further for initial control system configuration and life cycle management as well as for Engineering Test Bed applications and finally in full Scope Replica Simulators for Operator Training. (authors)

  9. A feedback control for the advanced launch system

    NASA Technical Reports Server (NTRS)

    Seywald, Hans; Cliff, Eugene M.

    1991-01-01

    A robust feedback algorithm is presented for a near-minimum-fuel ascent of a two-stage launch vehicle operating in the equatorial plane. The development of the algorithm is based on the ideas of neighboring optimal control and can be derived into three phases. In phase 1, the formalism of optimal control is employed to calculate fuel-optimal ascent trajectories for a simple point-mass model. In phase 2, these trajectories are used to numerically calculate gain functions of time for the control(s), the total flight time, and possibly, for other variables of interest. In phase 3, these gains are used to determine feedback expressions for the controls associated with a more realistic model of a launch vehicle. With the Advanced Launch System in mind, all calculations are performed on a two-stage vehicle with fixed thrust history, but this restriction is by no means important for the approach taken. Performance and robustness of the algorithm is found to be excellent.

  10. New advanced control methods for doubly salient permanent magnet motor

    SciTech Connect

    Blaabjerg, F.; Christensen, L.; Rasmussen, P.O.; Oestergaard, L.; Pedersen, P.

    1995-12-31

    High performance and high efficiency in adjustable speed drives are needed and new motor constructions are world wide investigated and analyzed. This paper deals with advanced control of a recently developed Doubly Salient Permanent Magnet (DSPM) motor. The construction of the DSPM motor is shown and a dynamical model of the motor is used for simulations. As supply to the DSPM motor, a power converter with a split capacitor is used to reduce the number of devices, and a basic control method for this converter is explained. This control method will cause an unequal voltage distribution across the capacitors because the motor is asymmetrical and a decrease in efficiency and a poorer dynamic performance are the results. To minimize the problems with the unequal load of the capacitors in the converter, a new charge control strategy is developed. The efficiency of the motor can also be improved by using a power minimizing scheme based on changing the turn-on and turn-off angles of the current. The two different strategies are implemented in an adjustable-speed drive, and it is concluded that both control strategies improve the performance of the drive.

  11. Modeling of ICRF Internal Transport Barrier Control for Advanced Tokamaks

    NASA Astrophysics Data System (ADS)

    Sund, R. S.; Scharer, J. E.

    1998-11-01

    We present an analysis of TFTR ICRF current drive experiments carried out by Majeski et al.(R. Majeski, J. Rodgers, G. Schilling, C. Phillips, J. Hosea and the TFTR Group, private communication.) The influence of deuterium, tritium, minority specie, electron and alpha concentrations, temperatures and beam fractions are considered for the two-ion mode conversion current drive experiments. Direct comparison with experimental data is carried out by means of a nonlocal large gyroradius ICRF code(O. Sauter, Ph.D. thesis, Ecole Polytechnique de Lausanne, Switzerland (1992).) which incorporates 1-D plasma profiles. It is found that substantial beam and alpha particle absorption can occur for some cases. Application of ion cyclotron range of frequencies internal transport barrier control requires further examination of fast wave mode conversion and the interaction of ion Bernstein waves with plasmas in advanced tokamaks. The effects of perpendicular and parallel magnetic gradients on the ion, electron, and alpha particle absorption are examined. A viable internal transport barrier control scheme for a reactor grade advanced tokamak will be discussed.

  12. Coal surface control for advanced fine coal flotation

    SciTech Connect

    Fuerstenau, D.W.; Sastry, K.V.S.; Hanson, J.S.; Diao, J.; De, A.; Sotillo, F.; Harris, G. ); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. ); Hu, Weibai; Zou, Y.; Chen, W. ); Choudhry, V.; Sehgal, R.; Ghosh, A. (Praxis Engineers, Inc., Milpitas, CA (United

    1991-07-30

    The primary objective in the scope of this research project is to develop advanced flotation methods for coal cleaning in order to achieve near total pyritic-sulfur removal at 90% Btu recovery, using coal samples procured from three major US coal seams. Concomitantly, the ash content of these coals is to be reduced to 6% or less. Investigation of mechanisms for the control of coal and pyrite surfaces prior to fine coal flotation is the main aspect of the project objectives. The results of this research are to be made available to ICF Kaiser Engineers who are currently working on the Engineering Development of Advanced Flotation under a separate contract with DOE under the Acid Rain Control Initiative program. A second major objective is to investigate factors involved in the progressive weathering and oxidation of coal that had been exposed to varying degrees of weathering, namely, open to the atmosphere, covered and in an argon-inerted'' atmosphere, over a period of twelve months. After regular intervals of weathering, samples of the three base coals (Illinois No. 6, Pittsburgh No. 8 and Upper Freeport PA) were collected and shipped to both the University of Pittsburgh and the University of California at Berkeley for characterization studies of the weathered material. 29 figs., 29 tabs.

  13. Advanced control of dissolved oxygen concentration in fed batch cultures during recombinant protein production.

    PubMed

    Kuprijanov, A; Gnoth, S; Simutis, R; Lübbert, A

    2009-02-01

    Design and experimental validation of advanced pO(2) controllers for fermentation processes operated in the fed-batch mode are described. In most situations, the presented controllers are able to keep the pO(2) in fermentations for recombinant protein productions exactly on the desired value. The controllers are based on the gain-scheduling approach to parameter-adaptive proportional-integral controllers. In order to cope with the most often appearing distortions, the basic gain-scheduling feedback controller was complemented with a feedforward control component. This feedforward/feedback controller significantly improved pO(2) control. By means of numerical simulations, the controller behavior was tested and its parameters were determined. Validation runs were performed with three Escherichia coli strains producing different recombinant proteins. It is finally shown that the new controller leads to significant improvements in the signal-to-noise ratio of other key process variables and, thus, to a higher process quality. PMID:19005652

  14. Experience with ISO quality control in assisted reproductive technology.

    PubMed

    Alper, Michael M

    2013-12-01

    Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement. PMID:24112531

  15. Quality control standards in PGD and PGS.

    PubMed

    SenGupta, S B; Dhanjal, S; Harper, J C

    2016-03-01

    Preimplantation genetic diagnosis (PGD) aims to test the embryo for specific conditions before implantation in couples at risk of transmitting genetic abnormality to their offspring. The couple must undergo IVF procedures to generate embryos in vitro. The embryos can be biopsied at either the zygote, cleavage or blastocyst stage. Preimplantation genetic screening uses the same technology to screen for chromosome abnormalities in embryos from patients undergoing IVF procedures as a method of embryo selection. Fluorescence in-situ hybridization was originally used for chromosome analysis, but has now been replaced by array comparative genomic hybridization or next generation sequencing. For the diagnosis of single gene defects, polymerase chain reaction is used and has become highly developed; however, single nucleotide polymorphism arrays for karyomapping have recently been introduced. A partnership between IVF laboratories and diagnostic centres is required to carry out PGD and preimplantation genetic screening. Accreditation of PGD diagnostic laboratories is important. Accreditation gives IVF centres an assurance that the diagnostic tests conform to specified standards. ISO 15189 is an international laboratory standard specific for medical laboratories. A requirement for accreditation is to participate in external quality assessment schemes. PMID:26776824

  16. Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Waco, TX.

    This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control…

  17. Quality Assurance and Quality Control Practices for Rehabilitation of Sewer and Water Mains

    EPA Science Inventory

    As part of the US Environmental Protection Agency (EPA)’s Aging Water Infrastructure Research Program, several areas of research are being pursued, including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of reha...

  18. HANDBOOK: QUALITY ASSURANCE/QUALITY CONTROL (QA/QC) PROCEDURES FOR HAZARDOUS WASTE INCINERATION

    EPA Science Inventory

    Resource Conservation and Recovery Act regulations for hazardous waste incineration require trial burns by permit applicants. uality Assurance Project Plan (QAPjP) must accompany a trial burn plan with appropriate quality assurance/quality control procedures. uidance on the prepa...

  19. Development and Testing of a Nuclear Quality Assurance/Quality Control Technician Curriculum. Final Report.

    ERIC Educational Resources Information Center

    Espy, John; And Others

    A project was conducted to field test selected first- and second-year courses in a postsecondary nuclear quality assurance/quality control (QA/QC) technician curriculum and to develop the teaching/learning modules for seven technical specialty courses remaining in the QA/QC technician curriculum. The field testing phase of the project involved the…

  20. Quality Assurance and Quality Control Practices For Rehabilitation of Sewer and Water Mains

    EPA Science Inventory

    As part of the US Environmental Protection Agency (EPA)’s Aging Water Infrastructure Research Program, several areas of research are being pursued including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of rehab...

  1. Quality control throughout the production process of infant food.

    PubMed

    Hamrin, Pia; Hoeft, Birgit

    2012-01-01

    The manufacture of infant food is a highly complex process and needs an effective quality control beyond classical in-process parameters and a final microbiological analysis. To ensure a safe end -product, various tools, such as the Hazard Analysis Critical Control Points (HACCP), have been developed to facilitate the management of food safety. Every single infant formula ingredient must have an excellent quality and safety approach because even if an ingredient is used in very small quantities in a single product, serious consequences may arise if the quality and product safety are not taken seriously by the ingredient manufacturer. The purpose of this article was twofold: firstly, to briefly describe existing Quality Management Systems and, secondly, to highlight the consequences of non-quality. PMID:22699770

  2. The process of managerial control in quality improvement initiatives.

    PubMed

    Slovensky, D J; Fottler, M D

    1994-11-01

    The fundamental intent of strategic management is to position an organization with in its market to exploit organizational competencies and strengths to gain competitive advantage. Competitive advantage may be achieved through such strategies as low cost, high quality, or unique services or products. For health care organizations accredited by the Joint Commission on Accreditation of Healthcare Organizations, continually improving both processes and outcomes of organizational performance--quality improvement--in all operational areas of the organization is a mandated strategy. Defining and measuring quality and controlling the quality improvement strategy remain problematic. The article discusses the nature and processes of managerial control, some potential measures of quality, and related information needs. PMID:10138526

  3. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    SciTech Connect

    Ye Zhuang; Stanley J. Miller; Grant E. Dunham; Michelle R. Olderbak

    2002-02-01

    Since 1995, DOE has supported development of a new concept in particulate control, called the advanced hybrid particulate collector (AHPC). The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emission with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a utility power plant to prove scaleup and demonstrate longer-term mercury control. This project, if successful, will demonstrate at the pilot-scale level a technology that would provide a cost-effective technique to accomplish control of mercury emissions and, at the same time, greatly enhance fine particulate collection efficiency. The technology can be used to retrofit systems currently employing inefficient ESP technology as well as for new construction, thereby providing a solution to a large segment of the U.S. utility industry as well as other industries requiring mercury control.

  4. Advanced Issues of Wind Turbine Modelling and Control

    NASA Astrophysics Data System (ADS)

    Simani, Silvio

    2015-11-01

    The motivation for this paper comes from a real need to have an overview about the challenges of modelling and control for very demanding systems, such as wind turbine systems, which require reliability, availability, maintainability, and safety over power conversion efficiency. These issues have begun to stimulate research and development in the wide control community particularly for these installations that need a high degree of “sustainability”. Note that this topic represents a key point mainly for offshore wind turbines with very large rotors, since they are characterised by challenging modelling and control problems, as well as expensive and safety critical maintenance works. In this case, a clear conflict exists between ensuring a high degree of availability and reducing maintenance times, which affect the final energy cost. On the other hand, wind turbines have highly nonlinear dynamics, with a stochastic and uncontrollable driving force as input in the form of wind speed, thus representing an interesting challenge also from the modelling point of view. Suitable control methods can provide a sustainable optimisation of the energy conversion efficiency over wider than normally expected working conditions. Moreover, a proper mathematical description of the wind turbine system should be able to capture the complete behaviour of the process under monitoring, thus providing an important impact on the control design itself. In this way, the control scheme could guarantee prescribed performance, whilst also giving a degree of “tolerance” to possible deviation of characteristic properties or system parameters from standard conditions, if properly included in the wind turbine model itself. The most important developments in advanced controllers for wind turbines are addressed, and open problems in the areas of modelling of wind turbines are also outlined.

  5. Research review: Indoor air quality control techniques

    SciTech Connect

    Fisk, W.J.

    1986-10-01

    Techniques for controlling the concentration of radon, formaldehyde, and combustion products in the indoor air are reviewed. The most effective techniques, which are generally based on limiting or reducing indoor pollutant source strengths, can decrease indoor pollutant concentrations by a factor of 3 to 10. Unless the initial ventilation rate is unusually low, it is difficult to reduce indoor pollutant concentrations more than approximately 50% by increasing the ventilation rate of an entire building. However, the efficiency of indoor pollutant control by ventilation can be enhanced through the use of local exhaust ventilation near concentrated sources of pollutants, by minimizing short circuiting of air from supply to exhaust when pollutant sources are dispersed and, in some situations, by promoting a displacement flow of air and pollutants toward the exhaust. Active air cleaning is also examined briefly. Filtration and electrostatic air cleaning for removal of particles from the indoor air are the most practical and effective currently available techniques of air cleaning. 49 refs., 7 figs.

  6. [Our experience with outside laboratory quality control].

    PubMed

    Dochev, D; Arakasheva, V; Nashkov, A; Tsachev, K

    1979-01-01

    The results from the national outside laboratory qualitative control of the clinical diagnostic laboratory investigations for the period September 1975 -- May 1977 were described. The following interlaboratory discrepancy was found on base of a systematic analysis of the data from the last two ring-like check-ups, November 1976 and May 1977, exressed by the variation coefficient (V.C. %); total protein, sodium, potassium and chlorides -- under 10%; cholesterol, urea and total fats -- between 10 and 20%; calcium, phosphorus, iron and creatinine -- over 20%. The highest per cent of admissible results are found with total protein -- to 85%; cholesterol -- to 70.38%; glucosa -- to 73.17%, urea -- to 69.23%, potassium -- to 59.46%, chlorides -- to 57.9%. With sodium, phosphorus, calcium, iron creatinine and uric acid the "admissibility" fluctuates about or under 50 per cent. The values of the qualitative-control indices discussed are comparable with the values obtained from them in the interlaboratory comparisons of other countries. PMID:494628

  7. Low-Cost Quality Control and Nondestructive Evaluation Technologies for General Aviation Structures

    NASA Technical Reports Server (NTRS)

    Cramer, K. Elliott; Gavinsky, Bob; Semanskee, Grant

    1998-01-01

    NASA's Advanced General Aviation Transport Experiments (AGATE) Program has as a goal to reduce the overall cost of producing private aviation aircraft while maintaining the safety of these aircraft. In order to successfully meet this goal, it is necessary to develop nondestructive inspection techniques which will facilitate the production of the materials used in these aircraft and assure the quality necessary to maintain airworthiness. This paper will discuss a particular class of general aviation materials and several nondestructive inspection techniques that have proven effective for making these inspections. Additionally, this paper will discuss the investigation and application of other commercially available quality control techniques applicable to these structures.

  8. 21 CFR 111.105 - What must quality control personnel do?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must quality control personnel do? 111.105... for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must... manufacturing record. To do so, quality control personnel must perform operations that include: (a) Approving...

  9. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  10. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  11. 21 CFR 111.105 - What must quality control personnel do?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What must quality control personnel do? 111.105... for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must... manufacturing record. To do so, quality control personnel must perform operations that include: (a) Approving...

  12. A quality comparison of preventive control schemes for media synchronization in voice and video communications

    NASA Astrophysics Data System (ADS)

    Minezawa, Satoshi; Ishibashi, Yutaka; Psannis, Kostas E.

    2007-09-01

    This paper assesses the media synchronization quality of preventive control schemes employed at media sources and media destinations for voice and video over a network. Preventive control is required to try to avoid asynchrony (i.e., out of synchronization). We here deal with two preventive control techniques employed at sources: Advancement of transmission timing of media units (MUs), each of which is the information unit for media synchronization (e.g., a video picture), with network delay estimation and temporal resolution control of video. We also handle three preventive control techniques employed at destinations: Change of buffering time with network delay estimation, preventive pausing, and preventive shortening of output duration. By experiment, we make a performance comparison among preventive control schemes which employ the preventive control techniques at sources and destinations. We also clarify the relations between subjective and objective assessment results.

  13. Statistical Process Control: Going to the Limit for Quality.

    ERIC Educational Resources Information Center

    Training, 1987

    1987-01-01

    Defines the concept of statistical process control, a quality control method used especially in manufacturing. Generally, concept users set specific standard levels that must be met. Makes the point that although employees work directly with the method, management is responsible for its success within the plant. (CH)

  14. Silicon Sheet Quality is Improved By Meniscus Control

    NASA Technical Reports Server (NTRS)

    Yates, D. A.; Hatch, A. E.; Goldsmith, J. M.

    1983-01-01

    Better quality silicon crystals for solar cells are possible with instrument that monitors position of meniscus as sheet of solid silicon is drawn from melt. Using information on meniscus height, instrument generates feedback signal to control melt temperature. Automatic control ensures more uniform silicon sheets.

  15. CRN5EXP: Expert system for statistical quality control

    NASA Technical Reports Server (NTRS)

    Hentea, Mariana

    1991-01-01

    The purpose of the Expert System CRN5EXP is to assist in checking the quality of the coils at two very important mills: Hot Rolling and Cold Rolling in a steel plant. The system interprets the statistical quality control charts, diagnoses and predicts the quality of the steel. Measurements of process control variables are recorded in a database and sample statistics such as the mean and the range are computed and plotted on a control chart. The chart is analyzed through patterns using the C Language Integrated Production System (CLIPS) and a forward chaining technique to reach a conclusion about the causes of defects and to take management measures for the improvement of the quality control techniques. The Expert System combines the certainty factors associated with the process control variables to predict the quality of the steel. The paper presents the approach to extract data from the database, the reason to combine certainty factors, the architecture and the use of the Expert System. However, the interpretation of control charts patterns requires the human expert's knowledge and lends to Expert Systems rules.

  16. Advanced Flow Control as a Management Tool in the National Airspace System

    NASA Technical Reports Server (NTRS)

    Wugalter, S.

    1974-01-01

    Advanced Flow Control is closely related to Air Traffic Control. Air Traffic Control is the business of the Federal Aviation Administration. To formulate an understanding of advanced flow control and its use as a management tool in the National Airspace System, it becomes necessary to speak somewhat of air traffic control, the role of FAA, and their relationship to advanced flow control. Also, this should dispell forever, any notion that advanced flow control is the inspirational master valve scheme to be used on the Alaskan Oil Pipeline.

  17. Designing in quality through design control: a manufacturer's perspective.

    PubMed

    Lasky, F D; Boser, R B

    1997-05-01

    Quality by design is a comprehensive program that begins with understanding user needs and continues through (but does not end with) monitoring customer acceptance. Management tools and processes such as ISO 9000 standards and the Food and Drug Administration Quality System Regulations exist to guide medical device manufacturers in quality practices. The goal is to deliver products acceptable for their intended use. Quality control begins with defining attributes ranging from color to accuracy and precision. Failure mode and effects analysis and risk analysis consider both probability and severity of potential malfunctions and their effects on patients or operators. Tools used to implement design and production practices include Program Evaluation and Review Technique (PERT) charts and industry-conceived concepts, such as Six Sigma techniques. Their use varies with manufacturer, depending on product and customer needs and the manufacturer's specific quality practices. Verification confirms that input goals are met. Then, validation assures that intended clinical needs are continually satisfied by establishing adequate production specifications. Conformance is monitored to verify that stable, consistent processes are in place, and precise user instructions enable the device to satisfy its intended use. Finally, complaint tracking can help assess whether needs have been met. Modifications in service, hardware, or instructions (including quality control) might be required. Therefore, both manufacturers and users work in partnership for continual improvement. The manufacturer's knowledge of design, production, and service needs of its devices enable it to recommend appropriate quality-control protocols for clinical testing. PMID:9166255

  18. Quality control loop for 3D laser beam cutting

    NASA Astrophysics Data System (ADS)

    Spitznagel, Juergen

    1996-08-01

    Existing systems for computer integrated manufacturing are based on the principle of the process chain: The product runs through different production sections as design, work planning and manufacturing in a sequential order. The data generated by a production sequence are transferred via interface to the following production sequence. These tightly-packed production sequences leave little scope for responding to quality deviations. This deficit is highlighted particularly in 3D laser cutting processes. In order to achieve an optimum machining result, a series of preliminary tests is required. Quality control loops play an important role in restricting the scope of necessary testing to a minimum. The represented control loop contains a CAD- system to design the workpiece, an offline-programming system to develop working strategies and NC/RC-programs as well as a shop-floor oriented tool to record quality data of the workpiece. The systems are coupled by an integrated product model. The control loop feeds quality data back to Operations Planning in the form of rules for processing strategies and technological data, so that the quality of the production process is enhanced. It is intended to supply optimum process parameters, so that the number of preliminary tests can be reduced. On the other hand the control loop contributes quality enhancement measures which serve as rules for the designers.

  19. Applying the Advancing Excellence in America's Nursing Homes Circle of Success to improving and sustaining quality.

    PubMed

    Bakerjian, Debra; Zisberg, Anna

    2013-01-01

    Looking forward to the Quality Assurance Performance Improvement (QAPI) program to be implemented and required in 2014, and as nursing home staff provide care for residents with increasingly complex health issues, knowledge of how to implement quality improvement (QI) is imperative. The nursing home administrator and director of nursing (DON) provide overall leadership, but it is the primary responsibility of the DON and other registered nurse staff to implement and manage the day to day QI process. This article describes potential roles of nursing leaders and key components of a QI project using a pressure ulcer case study exemplar to illustrate a quality improvement process. The authors suggest specific methods that RN leaders can employ using the Advancing Excellence Campaign Circle of Success as an organizing framework along with evidence-based resources. Nursing home leaders could use this article as a guideline for implementing any clinical quality improvement process. PMID:23870372

  20. Advanced information processing system: Hosting of advanced guidance, navigation and control algorithms on AIPS using ASTER

    NASA Technical Reports Server (NTRS)

    Brenner, Richard; Lala, Jaynarayan H.; Nagle, Gail A.; Schor, Andrei; Turkovich, John

    1994-01-01

    This program demonstrated the integration of a number of technologies that can increase the availability and reliability of launch vehicles while lowering costs. Availability is increased with an advanced guidance algorithm that adapts trajectories in real-time. Reliability is increased with fault-tolerant computers and communication protocols. Costs are reduced by automatically generating code and documentation. This program was realized through the cooperative efforts of academia, industry, and government. The NASA-LaRC coordinated the effort, while Draper performed the integration. Georgia Institute of Technology supplied a weak Hamiltonian finite element method for optimal control problems. Martin Marietta used MATLAB to apply this method to a launch vehicle (FENOC). Draper supplied the fault-tolerant computing and software automation technology. The fault-tolerant technology includes sequential and parallel fault-tolerant processors (FTP & FTPP) and authentication protocols (AP) for communication. Fault-tolerant technology was incrementally incorporated. Development culminated with a heterogeneous network of workstations and fault-tolerant computers using AP. Draper's software automation system, ASTER, was used to specify a static guidance system based on FENOC, navigation, flight control (GN&C), models, and the interface to a user interface for mission control. ASTER generated Ada code for GN&C and C code for models. An algebraic transform engine (ATE) was developed to automatically translate MATLAB scripts into ASTER.