Future lab-on-a-chip technologies for interrogating individual molecules.

PubMed

Craighead, Harold

2006-07-27

Advances in technology have allowed chemical sampling with high spatial resolution and the manipulation and measurement of individual molecules. Adaptation of these approaches to lab-on-a-chip formats is providing a new class of research tools for the investigation of biochemistry and life processes.

Diverse applications of advanced man-telerobot interfaces

NASA Technical Reports Server (NTRS)

Mcaffee, Douglas A.

1991-01-01

Advancements in man-machine interfaces and control technologies used in space telerobotics and teleoperators have potential application wherever human operators need to manipulate multi-dimensional spatial relationships. Bilateral six degree-of-freedom position and force cues exchanged between the user and a complex system can broaden and improve the effectiveness of several diverse man-machine interfaces.

Hyperparameter Classification of Arctic Sea Ice and Snow Based on Aerial Laser Data, Passive Microwave Data and Field Data

NASA Astrophysics Data System (ADS)

Herzfeld, U. C.; Maslanik, J.; Williams, S.; Sturm, M.; Cavalieri, D.

2006-12-01

In the past year, the Arctic sea-ice cover has been shrinking at an alarming rate. Remote-sensing technologies provide opportunities for observations of the sea ice at unprecedented repetition rates and spatial resolutions. The advance of new observational technologies is not only fascinating, it also brings with it the challenge and necessity to derive adequate new geoinformatical and geomathematical methods as a basis for analysis and geophysical interpretation of new data types. Our research includes validation and analysis of NASA EOS data, development of observational instrumentation and advanced geoinformatics. In this talk we emphasize the close linkage between technological development and geoinformatics along case studies of sea-ice near Point Barrow, Alaska, based on the following data types: AMSR-E and PSR passive microwave data, RADARSAT and ERS SAR data, manually-collected snow-depth data and laser-elevation data from unmanned aerial vehicles. The hyperparameter concept is introduced to facilitate characterization and classification of the same sea-ice properties and spatial structures from these data sets, which differ with respect to spatial resolution, measured parameters and observed geophysical variables. Mathematically, this requires parameter identification in undersampled, oversampled or overprinted situations.

Analysis and integration of spatial data for transportation planning.

DOT National Transportation Integrated Search

2009-06-01

Transportation planning requires substantial amounts of data and cooperation among transportation planning : agencies. Advances in computer technology and the increasing availability of geographic information : systems (GIS) are giving transportation...

Using spatial principles to optimize distributed computing for enabling the physical science discoveries

PubMed Central

Yang, Chaowei; Wu, Huayi; Huang, Qunying; Li, Zhenlong; Li, Jing

2011-01-01

Contemporary physical science studies rely on the effective analyses of geographically dispersed spatial data and simulations of physical phenomena. Single computers and generic high-end computing are not sufficient to process the data for complex physical science analysis and simulations, which can be successfully supported only through distributed computing, best optimized through the application of spatial principles. Spatial computing, the computing aspect of a spatial cyberinfrastructure, refers to a computing paradigm that utilizes spatial principles to optimize distributed computers to catalyze advancements in the physical sciences. Spatial principles govern the interactions between scientific parameters across space and time by providing the spatial connections and constraints to drive the progression of the phenomena. Therefore, spatial computing studies could better position us to leverage spatial principles in simulating physical phenomena and, by extension, advance the physical sciences. Using geospatial science as an example, this paper illustrates through three research examples how spatial computing could (i) enable data intensive science with efficient data/services search, access, and utilization, (ii) facilitate physical science studies with enabling high-performance computing capabilities, and (iii) empower scientists with multidimensional visualization tools to understand observations and simulations. The research examples demonstrate that spatial computing is of critical importance to design computing methods to catalyze physical science studies with better data access, phenomena simulation, and analytical visualization. We envision that spatial computing will become a core technology that drives fundamental physical science advancements in the 21st century. PMID:21444779

Using spatial principles to optimize distributed computing for enabling the physical science discoveries.

PubMed

Yang, Chaowei; Wu, Huayi; Huang, Qunying; Li, Zhenlong; Li, Jing

2011-04-05

Contemporary physical science studies rely on the effective analyses of geographically dispersed spatial data and simulations of physical phenomena. Single computers and generic high-end computing are not sufficient to process the data for complex physical science analysis and simulations, which can be successfully supported only through distributed computing, best optimized through the application of spatial principles. Spatial computing, the computing aspect of a spatial cyberinfrastructure, refers to a computing paradigm that utilizes spatial principles to optimize distributed computers to catalyze advancements in the physical sciences. Spatial principles govern the interactions between scientific parameters across space and time by providing the spatial connections and constraints to drive the progression of the phenomena. Therefore, spatial computing studies could better position us to leverage spatial principles in simulating physical phenomena and, by extension, advance the physical sciences. Using geospatial science as an example, this paper illustrates through three research examples how spatial computing could (i) enable data intensive science with efficient data/services search, access, and utilization, (ii) facilitate physical science studies with enabling high-performance computing capabilities, and (iii) empower scientists with multidimensional visualization tools to understand observations and simulations. The research examples demonstrate that spatial computing is of critical importance to design computing methods to catalyze physical science studies with better data access, phenomena simulation, and analytical visualization. We envision that spatial computing will become a core technology that drives fundamental physical science advancements in the 21st century.

Spatiotemporal models for data-anomaly detection in dynamic environmental monitoring campaigns

Treesearch

E.W. Dereszynski; T.G. Dietterich

2011-01-01

The ecological sciences have benefited greatly from recent advances in wireless sensor technologies. These technologies allow researchers to deploy networks of automated sensors, which can monitor a landscape at very fine temporal and spatial scales. However, these networks are subject to harsh conditions, which lead to malfunctions in individual sensors and failures...

NASA World Wind: Infrastructure for Spatial Data

NASA Technical Reports Server (NTRS)

Hogan, Patrick

2011-01-01

The world has great need for analysis of Earth observation data, be it climate change, carbon monitoring, disaster response, national defense or simply local resource management. To best provide for spatial and time-dependent information analysis, the world benefits from an open standards and open source infrastructure for spatial data. In the spirit of NASA's motto "for the benefit of all" NASA invites the world community to collaboratively advance this core technology. The World Wind infrastructure for spatial data both unites and challenges the world for innovative solutions analyzing spatial data while also allowing absolute command and control over any respective information exchange medium.

Advanced optical instruments technology

NASA Technical Reports Server (NTRS)

Shao, Mike; Chrisp, Michael; Cheng, Li-Jen; Eng, Sverre; Glavich, Thomas; Goad, Larry; Jones, Bill; Kaarat, Philip; Nein, Max; Robinson, William

1992-01-01

The science objectives for proposed NASA missions for the next decades push the state of the art in sensitivity and spatial resolution over a wide range of wavelengths, including the x-ray to the submillimeter. While some of the proposed missions are larger and more sensitive versions of familiar concepts, such as the next generation space telescope, others use concepts, common on the Earth, but new to space, such as optical interferometry, in order to provide spatial resolutions impossible with other concepts. However, despite their architecture, the performance of all of the proposed missions depends critically on the back-end instruments that process the collected energy to produce scientifically interesting outputs. The Advanced Optical Instruments Technology panel was chartered with defining technology development plans that would best improve optical instrument performance for future astrophysics missions. At this workshop the optical instrument was defined as the set of optical components that reimage the light from the telescope onto the detectors to provide information about the spatial, spectral, and polarization properties of the light. This definition was used to distinguish the optical instrument technology issues from those associated with the telescope, which were covered by a separate panel. The panel identified several areas for optical component technology development: diffraction gratings; tunable filters; interferometric beam combiners; optical materials; and fiber optics. The panel also determined that stray light suppression instruments, such as coronagraphs and nulling interferometers, were in need of general development to support future astrophysics needs.

Advanced optical instruments technology

NASA Astrophysics Data System (ADS)

Shao, Mike; Chrisp, Michael; Cheng, Li-Jen; Eng, Sverre; Glavich, Thomas; Goad, Larry; Jones, Bill; Kaarat, Philip; Nein, Max; Robinson, William

1992-08-01

The science objectives for proposed NASA missions for the next decades push the state of the art in sensitivity and spatial resolution over a wide range of wavelengths, including the x-ray to the submillimeter. While some of the proposed missions are larger and more sensitive versions of familiar concepts, such as the next generation space telescope, others use concepts, common on the Earth, but new to space, such as optical interferometry, in order to provide spatial resolutions impossible with other concepts. However, despite their architecture, the performance of all of the proposed missions depends critically on the back-end instruments that process the collected energy to produce scientifically interesting outputs. The Advanced Optical Instruments Technology panel was chartered with defining technology development plans that would best improve optical instrument performance for future astrophysics missions. At this workshop the optical instrument was defined as the set of optical components that reimage the light from the telescope onto the detectors to provide information about the spatial, spectral, and polarization properties of the light. This definition was used to distinguish the optical instrument technology issues from those associated with the telescope, which were covered by a separate panel. The panel identified several areas for optical component technology development: diffraction gratings; tunable filters; interferometric beam combiners; optical materials; and fiber optics. The panel also determined that stray light suppression instruments, such as coronagraphs and nulling interferometers, were in need of general development to support future astrophysics needs.

Review of spectral imaging technology in biomedical engineering: achievements and challenges.

PubMed

Li, Qingli; He, Xiaofu; Wang, Yiting; Liu, Hongying; Xu, Dongrong; Guo, Fangmin

2013-10-01

Spectral imaging is a technology that integrates conventional imaging and spectroscopy to get both spatial and spectral information from an object. Although this technology was originally developed for remote sensing, it has been extended to the biomedical engineering field as a powerful analytical tool for biological and biomedical research. This review introduces the basics of spectral imaging, imaging methods, current equipment, and recent advances in biomedical applications. The performance and analytical capabilities of spectral imaging systems for biological and biomedical imaging are discussed. In particular, the current achievements and limitations of this technology in biomedical engineering are presented. The benefits and development trends of biomedical spectral imaging are highlighted to provide the reader with an insight into the current technological advances and its potential for biomedical research.

Greenhouse gas emission curves for advanced biofuel supply chains

NASA Astrophysics Data System (ADS)

Daioglou, Vassilis; Doelman, Jonathan C.; Stehfest, Elke; Müller, Christoph; Wicke, Birka; Faaij, Andre; van Vuuren, Detlef P.

2017-12-01

Most climate change mitigation scenarios that are consistent with the 1.5-2 °C target rely on a large-scale contribution from biomass, including advanced (second-generation) biofuels. However, land-based biofuel production has been associated with substantial land-use change emissions. Previous studies show a wide range of emission factors, often hiding the influence of spatial heterogeneity. Here we introduce a spatially explicit method for assessing the supply of advanced biofuels at different emission factors and present the results as emission curves. Dedicated crops grown on grasslands, savannahs and abandoned agricultural lands could provide 30 EJBiofuel yr-1 with emission factors less than 40 kg of CO2-equivalent (CO2e) emissions per GJBiofuel (for an 85-year time horizon). This increases to 100 EJBiofuel yr-1 for emission factors less than 60 kgCO2e GJBiofuel-1. While these results are uncertain and depend on model assumptions (including time horizon, spatial resolution, technology assumptions and so on), emission curves improve our understanding of the relationship between biofuel supply and its potential contribution to climate change mitigation while accounting for spatial heterogeneity.

Industrial implementation of spatial variability control by real-time SPC

NASA Astrophysics Data System (ADS)

Roule, O.; Pasqualini, F.; Borde, M.

2016-10-01

Advanced technology nodes require more and more information to get the wafer process well setup. The critical dimension of components decreases following Moore's law. At the same time, the intra-wafer dispersion linked to the spatial non-uniformity of tool's processes is not capable to decrease in the same proportions. APC systems (Advanced Process Control) are being developed in waferfab to automatically adjust and tune wafer processing, based on a lot of process context information. It can generate and monitor complex intrawafer process profile corrections between different process steps. It leads us to put under control the spatial variability, in real time by our SPC system (Statistical Process Control). This paper will outline the architecture of an integrated process control system for shape monitoring in 3D, implemented in waferfab.

Statistical and Economic Techniques for Site-specific Nematode Management.

PubMed

Liu, Zheng; Griffin, Terry; Kirkpatrick, Terrence L

2014-03-01

Recent advances in precision agriculture technologies and spatial statistics allow realistic, site-specific estimation of nematode damage to field crops and provide a platform for the site-specific delivery of nematicides within individual fields. This paper reviews the spatial statistical techniques that model correlations among neighboring observations and develop a spatial economic analysis to determine the potential of site-specific nematicide application. The spatial econometric methodology applied in the context of site-specific crop yield response contributes to closing the gap between data analysis and realistic site-specific nematicide recommendations and helps to provide a practical method of site-specifically controlling nematodes.

Pilot vehicle interface on the advanced fighter technology integration F-16

NASA Technical Reports Server (NTRS)

Dana, W. H.; Smith, W. B.; Howard, J. D.

1986-01-01

This paper focuses on the work load aspects of the pilot vehicle interface in regard to the new technologies tested during AMAS Phase II. Subjects discussed in this paper include: a wide field-of-view head-up display; automated maneuvering attack system/sensor tracker system; master modes that configure flight controls and mission avionics; a modified helmet mounted sight; improved multifunction display capability; a voice interactive command system; ride qualities during automated weapon delivery; a color moving map; an advanced digital map display; and a g-induced loss-of-consciousness and spatial disorientation autorecovery system.

Incorporating digital imaging into dental hygiene practice.

PubMed

Saxe, M J; West, D J

1997-01-01

The objective of this paper is to describe digital imaging technology: available modalities, scientific imaging process, advantages and limitations, and applications to dental hygiene practice. Advances in technology have created innovative imaging modalities for intraoral radiography that eliminate film as the traditional image receptor. Digital imaging generates instantaneous radiographic images on a display monitor following exposure. Advantages include lower patient exposure per image and elimination of film processing. Digital imaging enhances diagnostic capabilities and, therefore, treatment decisions by the oral healthcare provider. Utilization of digital imaging technology for intraoral radiography will advance the practice of dental hygiene. Although spatial resolution is inferior to conventional film, digital imaging provides adequate resolution to diagnose oral diseases. Dental hygienists must evaluate new technologies in radiography to continue providing quality care while reducing patient exposure to ionizing radiation.

Advancing Geospatial Technologies in Science and Social Science: A Case Study in Collaborative Education

NASA Astrophysics Data System (ADS)

Williams, N. A.; Morris, J. N.; Simms, M. L.; Metoyer, S.

2007-12-01

The Advancing Geospatial Skills in Science and Social Sciences (AGSSS) program, funded by NSF, provides middle and high school teacher-partners with access to graduate student scientists for classroom collaboration and curriculum adaptation to incorporate and advance skills in spatial thinking. AGSSS Fellows aid in the delivery of geospatially-enhanced activities utilizing technology such as geographic information systems, remote sensing, and virtual globes. The partnership also provides advanced professional development for both participating teachers and fellows. The AGSSS program is mutually beneficial to all parties involved. This successful collaboration of scientists, teachers, and students results in greater understanding and enthusiasm for the use of spatial thinking strategies and geospatial technologies. In addition, the partnership produces measurable improvements in student efficacy and attitudes toward processes of spatial thinking. The teacher partner training and classroom resources provided by AGSSS will continue the integration of geospatial activities into the curriculum after the project concludes. Time and resources are the main costs in implementing this partnership. Graduate fellows invest considerable time and energy, outside of academic responsibilities, to develop materials for the classroom. Fellows are required to be available during K-12 school hours, which necessitates forethought in scheduling other graduate duties. However, the benefits far outweigh the costs. Graduate fellows gain experience in working in classrooms. In exchange, students gain exposure to working scientists and their research. This affords graduate fellows the opportunity to hone their communication skills, and specifically allows them to address the issue of translating technical information for a novice audience. Teacher-partners and students benefit by having scientific expertise readily available. In summation, these experiences result in changes in teacher/student perceptions of science and scientists. Evidence of the aforementioned changes are provided through external evaluation and results obtained from several assessment tools. The program also utilizes an internal evaluator to monitor participants thoughts and opinions on the previous years' collaboration. Additionally, graduate fellows maintain a reflective journal to provide insight into experiences occurring both in-class and among peers. Finally, student surveys administered prior to and concluding the academic year assess changes in student attitudes and self-perception of spatial thinking skills.

Emerging technological and cultural shifts advancing drylands research and management

USDA-ARS?s Scientific Manuscript database

Sustainable provisioning of ecosystem services in dryland landscapes is complicated by extreme conditions that constrain biological responses to perturbation, vast spatial and temporal complexity, and uncertainty regarding the resilience of these ecosystems to management practices and climate change...

Enhancing Spatial Resolution of Remotely Sensed Imagery Using Deep Learning

NASA Astrophysics Data System (ADS)

Beck, J. M.; Bridges, S.; Collins, C.; Rushing, J.; Graves, S. J.

2017-12-01

Researchers at the Information Technology and Systems Center at the University of Alabama in Huntsville are using Deep Learning with Convolutional Neural Networks (CNNs) to develop a method for enhancing the spatial resolutions of moderate resolution (10-60m) multispectral satellite imagery. This enhancement will effectively match the resolutions of imagery from multiple sensors to provide increased global temporal-spatial coverage for a variety of Earth science products. Our research is centered on using Deep Learning for automatically generating transformations for increasing the spatial resolution of remotely sensed images with different spatial, spectral, and temporal resolutions. One of the most important steps in using images from multiple sensors is to transform the different image layers into the same spatial resolution, preferably the highest spatial resolution, without compromising the spectral information. Recent advances in Deep Learning have shown that CNNs can be used to effectively and efficiently upscale or enhance the spatial resolution of multispectral images with the use of an auxiliary data source such as a high spatial resolution panchromatic image. In contrast, we are using both the spatial and spectral details inherent in low spatial resolution multispectral images for image enhancement without the use of a panchromatic image. This presentation will discuss how this technology will benefit many Earth Science applications that use remotely sensed images with moderate spatial resolutions.

Nebhydro: Sharing Geospatial Data to Supportwater Management in Nebraska

NASA Astrophysics Data System (ADS)

Kamble, B.; Irmak, A.; Hubbard, K.; Deogun, J.; Dvorak, B.

2012-12-01

Recent advances in web-enabled geographical technologies have the potential to make a dramatic impact on development of highly interactive spatial applications on the web for visualization of large-scale geospatial data by water resources and irrigation scientists. Spatial and point scale water resources data visualization are an emerging and challenging application domain. Query based visual explorations of geospatial hydrological data can play an important role in stimulating scientific hypotheses and seeking causal relationships among hydro variables. The Nebraska Hydrological Information System (NebHydro) utilizes ESRI's ArcGIS server technology to increase technological awareness among farmers, irrigation managers and policy makers. Web-based geospatial applications are an effective way to expose scientific hydrological datasets to the research community and the public. NebHydro uses Adobe Flex technology to offer an online visualization and data analysis system for presentation of social and economic data. Internet mapping services is an integrated product of GIS and Internet technologies; it is a favored solution to achieve the interoperability of GIS. The development of Internet based GIS services in the state of Nebraska showcases the benefits of sharing geospatial hydrological data among agencies, resource managers and policy makers. Geospatial hydrological Information (Evapotranspiration from Remote Sensing, vegetation indices (NDVI), USGS Stream gauge data, Climatic data etc.) is generally generated through model simulation (METRIC, SWAP, Linux, Python based scripting etc). Information is compiled into and stored within object oriented relational spatial databases using a geodatabase information model that supports the key data types needed by applications including features, relationships, networks, imagery, terrains, maps and layers. The system provides online access, querying, visualization, and analysis of the hydrological data from several sources at one place. The study indicates that internet GIS, developed using advanced technologies, provides valuable education potential to users in hydrology and irrigation engineering and suggests that such a system can support advanced hydrological data access and analysis tools to improve utility of data in operations. Keywords: Hydrological Information System, NebHydro, Water Management, data sharing, data visualization, ArcGIS server.

Spatial light modulators and applications III; Proceedings of the Meeting, San Diego, CA, Aug. 7, 8, 1989

NASA Astrophysics Data System (ADS)

Efron, Uzi

Recent advances in the technology and applications of spatial light modulators (SLMs) are discussed in review essays by leading experts. Topics addressed include materials for SLMs, SLM devices and device technology, applications to optical data processing, and applications to artificial neural networks. Particular attention is given to nonlinear optical polymers, liquid crystals, magnetooptic SLMs, multiple-quantum-well SLMs, deformable-mirror SLMs, three-dimensional optical memories, applications of photorefractive devices to optical computing, photonic neurocomputers and learning machines, holographic associative memories, SLMs as parallel memories for optoelectronic neural networks, and coherent-optics implementations of neural-network models.

Spatial light modulators and applications III; Proceedings of the Meeting, San Diego, CA, Aug. 7, 8, 1989

NASA Technical Reports Server (NTRS)

Efron, Uzi (Editor)

1990-01-01

Recent advances in the technology and applications of spatial light modulators (SLMs) are discussed in review essays by leading experts. Topics addressed include materials for SLMs, SLM devices and device technology, applications to optical data processing, and applications to artificial neural networks. Particular attention is given to nonlinear optical polymers, liquid crystals, magnetooptic SLMs, multiple-quantum-well SLMs, deformable-mirror SLMs, three-dimensional optical memories, applications of photorefractive devices to optical computing, photonic neurocomputers and learning machines, holographic associative memories, SLMs as parallel memories for optoelectronic neural networks, and coherent-optics implementations of neural-network models.

Confidentiality and spatially explicit data: Concerns and challenges

PubMed Central

VanWey, Leah K.; Rindfuss, Ronald R.; Gutmann, Myron P.; Entwisle, Barbara; Balk, Deborah L.

2005-01-01

Recent theoretical, methodological, and technological advances in the spatial sciences create an opportunity for social scientists to address questions about the reciprocal relationship between context (spatial organization, environment, etc.) and individual behavior. This emerging research community has yet to adequately address the new threats to the confidentiality of respondent data in spatially explicit social survey or census data files, however. This paper presents four sometimes conflicting principles for the conduct of ethical and high-quality science using such data: protection of confidentiality, the social–spatial linkage, data sharing, and data preservation. The conflict among these four principles is particularly evident in the display of spatially explicit data through maps combined with the sharing of tabular data files. This paper reviews these two research activities and shows how current practices favor one of the principles over the others and do not satisfactorily resolve the conflict among them. Maps are indispensable for the display of results but also reveal information on the location of respondents and sampling clusters that can then be used in combination with shared data files to identify respondents. The current practice of sharing modified or incomplete data sets or using data enclaves is not ideal for either the advancement of science or the protection of confidentiality. Further basic research and open debate are needed to advance both understanding of and solutions to this dilemma. PMID:16230608

EVALUATING LANDSCAPE CHANGE AND HYDROLOGICAL CONSEQUENCES IN A SEMI-ARID ENVIRONMENT

EPA Science Inventory

During the past two decades, important advances in the integration of remote imagery, computer processing, and spatial analysis technologies have been used to better understand the distribution of natural communities and ecosystems, and the ecological processes that affect these ...

Reasoning with Geometric Shapes

ERIC Educational Resources Information Center

Seah, Rebecca

2015-01-01

Geometry belongs to branches of mathematics that develop students' visualisation, intuition, critical thinking, problem solving, deductive reasoning, logical argument and proof (Jones, 2002). It provides the basis for the development of spatial sense and plays an important role in acquiring advanced knowledge in science, technology, engineering,…

Inclusions and Their Influence on Material Behavior: Proceedings of a Symposium Held in Conjunction with the 1988 World Materials Congress, Chicago, Illinois, USA, 24-30 September 1988

DTIC Science & Technology

1988-01-01

Columbus Division V TABLE OF CONTENTS Inclusions: Advantages, Disadvantages, and the Technological Trends ................. 1 R. Rungta, A. J...these phases [1]. A similar summary of sulphide Advances in noninvasive technologies for de- inclusions important to steel making is shown in tecting and...MEASUREMENT OF SPATIAL DISTRIBUTION OF INCLUSIONS M. T. Shehata, J. D. Boyd Metals Technology Laboratories CANMET - Energy, Mines & Resources Canada Ottawa

Advanced sensors and instrumentation

NASA Technical Reports Server (NTRS)

Calloway, Raymond S.; Zimmerman, Joe E.; Douglas, Kevin R.; Morrison, Rusty

1990-01-01

NASA is currently investigating the readiness of Advanced Sensors and Instrumentation to meet the requirements of new initiatives in space. The following technical objectives and technologies are briefly discussed: smart and nonintrusive sensors; onboard signal and data processing; high capacity and rate adaptive data acquisition systems; onboard computing; high capacity and rate onboard storage; efficient onboard data distribution; high capacity telemetry; ground and flight test support instrumentation; power distribution; and workstations, video/lighting. The requirements for high fidelity data (accuracy, frequency, quantity, spatial resolution) in hostile environments will continue to push the technology developers and users to extend the performance of their products and to develop new generations.

Every photon counts: improving low, mid, and high-spatial frequency errors on astronomical optics and materials with MRF

NASA Astrophysics Data System (ADS)

Maloney, Chris; Lormeau, Jean Pierre; Dumas, Paul

2016-07-01

Many astronomical sensing applications operate in low-light conditions; for these applications every photon counts. Controlling mid-spatial frequencies and surface roughness on astronomical optics are critical for mitigating scattering effects such as flare and energy loss. By improving these two frequency regimes higher contrast images can be collected with improved efficiency. Classically, Magnetorheological Finishing (MRF) has offered an optical fabrication technique to correct low order errors as well has quilting/print-through errors left over in light-weighted optics from conventional polishing techniques. MRF is a deterministic, sub-aperture polishing process that has been used to improve figure on an ever expanding assortment of optical geometries, such as planos, spheres, on and off axis aspheres, primary mirrors and freeform optics. Precision optics are routinely manufactured by this technology with sizes ranging from 5-2,000mm in diameter. MRF can be used for form corrections; turning a sphere into an asphere or free form, but more commonly for figure corrections achieving figure errors as low as 1nm RMS while using careful metrology setups. Recent advancements in MRF technology have improved the polishing performance expected for astronomical optics in low, mid and high spatial frequency regimes. Deterministic figure correction with MRF is compatible with most materials, including some recent examples on Silicon Carbide and RSA905 Aluminum. MRF also has the ability to produce `perfectly-bad' compensating surfaces, which may be used to compensate for measured or modeled optical deformation from sources such as gravity or mounting. In addition, recent advances in MRF technology allow for corrections of mid-spatial wavelengths as small as 1mm simultaneously with form error correction. Efficient midspatial frequency corrections make use of optimized process conditions including raster polishing in combination with a small tool size. Furthermore, a novel MRF fluid, called C30, has been developed to finish surfaces to ultra-low roughness (ULR) and has been used as the low removal rate fluid required for fine figure correction of mid-spatial frequency errors. This novel MRF fluid is able to achieve <4Å RMS on Nickel-plated Aluminum and even <1.5Å RMS roughness on Silicon, Fused Silica and other materials. C30 fluid is best utilized within a fine figure correction process to target mid-spatial frequency errors as well as smooth surface roughness 'for free' all in one step. In this paper we will discuss recent advancements in MRF technology and the ability to meet requirements for precision optics in low, mid and high spatial frequency regimes and how improved MRF performance addresses the need for achieving tight specifications required for astronomical optics.

GeoSpatial Workforce Development: enhancing the traditional learning environment in geospatial information technology

NASA Astrophysics Data System (ADS)

Lawhead, Pamela B.; Aten, Michelle L.

2003-04-01

The Center for GeoSpatial Workforce Development is embarking on a new era in education by developing a repository of dynamic online courseware authored by the foremost industry experts within the remote sensing and GIS industries. Virtual classrooms equipped with the most advanced instructions, computations, communications, course evaluation, and management facilities amplify these courses to enhance the learning environment and provide rapid feedback between instructors and students. The launch of this program included the objective development of the Model Curriculum by an independent consortium of remote sensing industry leaders. The Center's research and development focus on recruiting additional industry experts to develop the technical content of the courseware and then utilize state-of-the-art technology to enhance their material with visually stimulating animations, compelling audio clips and entertaining, interactive exercises intended to reach the broadest audience possible by targeting various learning styles. The courseware will be delivered via various media: Internet, CD-ROM, DVD, and compressed video, that translates into anywhere, anytime delivery of GeoSpatial Information Technology education.

Recent advances in the applications of vibrational spectroscopic imaging and mapping to pharmaceutical formulations

NASA Astrophysics Data System (ADS)

Ewing, Andrew V.; Kazarian, Sergei G.

2018-05-01

Vibrational spectroscopic imaging and mapping approaches have continued in their development and applications for the analysis of pharmaceutical formulations. Obtaining spatially resolved chemical information about the distribution of different components within pharmaceutical formulations is integral for improving the understanding and quality of final drug products. This review aims to summarise some key advances of these technologies over recent years, primarily since 2010. An overview of FTIR, NIR, terahertz spectroscopic imaging and Raman mapping will be presented to give a perspective of the current state-of-the-art of these techniques for studying pharmaceutical samples. This will include their application to reveal spatial information of components that reveals molecular insight of polymorphic or structural changes, behaviour of formulations during dissolution experiments, uniformity of materials and detection of counterfeit products. Furthermore, new advancements will be presented that demonstrate the continuing novel applications of spectroscopic imaging and mapping, namely in FTIR spectroscopy, for studies of microfluidic devices. Whilst much of the recently developed work has been reported by academic groups, examples of the potential impacts of utilising these imaging and mapping technologies to support industrial applications have also been reviewed.

Advanced Optical Technologies for Defense Trauma and Critical Care

DTIC Science & Technology

2014-02-04

conventional LSI. We also demonstrated that mcLSI enables improved characterization of curved surfaces of the body by positioning LSI modules at...Implementation of an LED based clinical spatial frequency domain imaging 17 system. Proc SPIE Vol. 8254, Emerging Digital Micromirror Device Based

An overview of ecological monitoring based on geographic information system (GIS) and remote sensing (RS) technology in China

NASA Astrophysics Data System (ADS)

Zhang, Jing; Zhang, Jia; Du, Xiangyang; Kang, Hou; Qiao, Minjuan

2017-11-01

Due to the rapid development of human economy and society, the resulting ecological problems are becoming more and more prominent, and the dynamic monitoring of the various elements in the ecosystem has become the focus of the current research. For the complex structure and function of the ecological environment monitoring, advanced technical means should be adopted. With the development of spatial information technology, the ecological monitoring technology based on GIS and RS is becoming more and more perfect, and spatial analysis will play an important role in the field of environmental protection. Based on the GIS and RS technology, this paper analyzes the general centralized ecological monitoring model, and makes an objective analysis of the current ecological monitoring trend of China. These are important for the protection and management of ecological environment in China.

Spatial Dmbs Architecture for a Free and Open Source Bim

NASA Astrophysics Data System (ADS)

Logothetis, S.; Valari, E.; Karachaliou, E.; Stylianidis, E.

2017-08-01

Recent research on the field of Building Information Modelling (BIM) technology, revealed that except of a few, accessible and free BIM viewers there is a lack of Free & Open Source Software (FOSS) BIM software for the complete BIM process. With this in mind and considering BIM as the technological advancement of Computer-Aided Design (CAD) systems, the current work proposes the use of a FOSS CAD software in order to extend its capabilities and transform it gradually into a FOSS BIM platform. Towards this undertaking, a first approach on developing a spatial Database Management System (DBMS) able to store, organize and manage the overall amount of information within a single application, is presented.

THE SAN PEDRO RIVER SPATIAL DATA ARCHIVE, A DATABASE BROWSER FOR COMMUNITY-BASED ENVIRONMENTAL PROTECTION

EPA Science Inventory

It is currently possible to measure landscape change over large areas and determine trends in ecological and hydrological condition using advanced space-based technologies accompanied by geospatial data. Specifically, this process is being tested in a community-based watershed in...

THE SAN PEDRO SPATIAL DATA ARCHIVE, A DATABASE BROWSER FOR COMMUNITY-BASED ENVIRONMENTAL PROTECTION

EPA Science Inventory

It is currently possible to measure landscape change over large areas and determine trends in ecological and hydrological condition using advanced space-based technologies accompanied by geospatial data. Specifically, this process is being tested in a community-based watershed in...

Recent technologic advances in multi-detector row cardiac CT.

PubMed

Halliburton, Sandra Simon

2009-11-01

Recent technical advances in multi-detector row CT have resulted in lower radiation dose, improved temporal and spatial resolution, decreased scan time, and improved tissue differentiation. Lower radiation doses have resulted from the use of pre-patient z collimators, the availability of thin-slice axial data acquisition, the increased efficiency of ECG-based tube current modulation, and the implementation of iterative reconstruction algorithms. Faster gantry rotation and the simultaneous use of two x-ray sources have led to improvements in temporal resolution, and gains in spatial resolution have been achieved through application of the flying x-ray focal-spot technique in the z-direction. Shorter scan times have resulted from the design of detector arrays with increasing numbers of detector rows and through the simultaneous use of two x-ray sources to allow higher helical pitch. Some improvement in tissue differentiation has been achieved with dual energy CT. This article discusses these recent technical advances in detail.

Concise Review: Organ Engineering: Design, Technology, and Integration.

PubMed

Kaushik, Gaurav; Leijten, Jeroen; Khademhosseini, Ali

2017-01-01

Engineering complex tissues and whole organs has the potential to dramatically impact translational medicine in several avenues. Organ engineering is a discipline that integrates biological knowledge of embryological development, anatomy, physiology, and cellular interactions with enabling technologies including biocompatible biomaterials and biofabrication platforms such as three-dimensional bioprinting. When engineering complex tissues and organs, core design principles must be taken into account, such as the structure-function relationship, biochemical signaling, mechanics, gradients, and spatial constraints. Technological advances in biomaterials, biofabrication, and biomedical imaging allow for in vitro control of these factors to recreate in vivo phenomena. Finally, organ engineering emerges as an integration of biological design and technical rigor. An overall workflow for organ engineering and guiding technology to advance biology as well as a perspective on necessary future iterations in the field is discussed. Stem Cells 2017;35:51-60. © 2016 AlphaMed Press.

Growing a Global Perspective: Utilizing Graduate Students as Scientists in the Classroom

NASA Astrophysics Data System (ADS)

Martinez, A.; Prouhet, T.; Kincaid, J.; Williams, N.; Simms, M.; Evans, R.

2006-12-01

Advancing Geospatial Skills in Science and Social Sciences (AGSSS) is a NSF GK12 program designed to produce scientists with an interest in and skills related to education by bringing graduate students (termed Fellows) into science and social science classrooms. The AGSSS program is unique in the GK-12 program because of its emphasis on spatial thinking with and through geospatial technologies. Spatial thinking is defined as the knowledge, skills, and habits of mind to use concepts of space, tools of representation, and processes of reasoning to structure problems, find answers and express solutions to these problems. Working collaboratively, Fellows assist teachers in using technologies (many freely available) such as virtual globes, GIS, GPS, NASA's ISSEarthKAM, and online databases. Fellows also customize existing curricula based on teacher requests to focus on spatial thinking and skill development. Preliminary results of the program reveal that students' use of geospatial technologies in interactive lessons that highlight real world processes and global perspectives encourages the development of higher order thinking skills. Fellows perceive three primary benefits: developing collaboration and communication skills, solidifying their own understandings of spatial thinking and becoming more aware and skilled in working in educational settings.

High-speed limnology: using advanced sensors to investigate spatial variability in biogeochemistry and hydrology.

PubMed

Crawford, John T; Loken, Luke C; Casson, Nora J; Smith, Colin; Stone, Amanda G; Winslow, Luke A

2015-01-06

Advanced sensor technology is widely used in aquatic monitoring and research. Most applications focus on temporal variability, whereas spatial variability has been challenging to document. We assess the capability of water chemistry sensors embedded in a high-speed water intake system to document spatial variability. This new sensor platform continuously samples surface water at a range of speeds (0 to >45 km h(-1)) resulting in high-density, mesoscale spatial data. These novel observations reveal previously unknown variability in physical, chemical, and biological factors in streams, rivers, and lakes. By combining multiple sensors into one platform, we were able to detect terrestrial-aquatic hydrologic connections in a small dystrophic lake, to infer the role of main-channel vs backwater nutrient processing in a large river and to detect sharp chemical changes across aquatic ecosystem boundaries in a stream/lake complex. Spatial sensor data were verified in our examples by comparing with standard lab-based measurements of selected variables. Spatial fDOM data showed strong correlation with wet chemistry measurements of DOC, and optical NO3 concentrations were highly correlated with lab-based measurements. High-frequency spatial data similar to our examples could be used to further understand aquatic biogeochemical fluxes, ecological patterns, and ecosystem processes, and will both inform and benefit from fixed-site data.

High-speed limnology: Using advanced sensors to investigate spatial variability in biogeochemistry and hydrology

USGS Publications Warehouse

Crawford, John T.; Loken, Luke C.; Casson, Nora J.; Smith, Collin; Stone, Amanda G.; Winslow, Luke A.

2015-01-01

Advanced sensor technology is widely used in aquatic monitoring and research. Most applications focus on temporal variability, whereas spatial variability has been challenging to document. We assess the capability of water chemistry sensors embedded in a high-speed water intake system to document spatial variability. This new sensor platform continuously samples surface water at a range of speeds (0 to >45 km h–1) resulting in high-density, mesoscale spatial data. These novel observations reveal previously unknown variability in physical, chemical, and biological factors in streams, rivers, and lakes. By combining multiple sensors into one platform, we were able to detect terrestrial–aquatic hydrologic connections in a small dystrophic lake, to infer the role of main-channel vs backwater nutrient processing in a large river and to detect sharp chemical changes across aquatic ecosystem boundaries in a stream/lake complex. Spatial sensor data were verified in our examples by comparing with standard lab-based measurements of selected variables. Spatial fDOM data showed strong correlation with wet chemistry measurements of DOC, and optical NO3 concentrations were highly correlated with lab-based measurements. High-frequency spatial data similar to our examples could be used to further understand aquatic biogeochemical fluxes, ecological patterns, and ecosystem processes, and will both inform and benefit from fixed-site data.

Photoacoustic microscopy and computed tomography: from bench to bedside

PubMed Central

Wang, Lihong V.; Gao, Liang

2014-01-01

Photoacoustic imaging (PAI) of biological tissue has seen immense growth in the past decade, providing unprecedented spatial resolution and functional information at depths in the optical diffusive regime. PAI uniquely combines the advantages of optical excitation and acoustic detection. The hybrid imaging modality features high sensitivity to optical absorption and wide scalability of spatial resolution with the desired imaging depth. Here we first summarize the fundamental principles underpinning the technology, then highlight its practical implementation, and finally discuss recent advances towards clinical translation. PMID:24905877

Advanced Methods for Incorporating Solar Energy Technologies into Electric Sector Capacity-Expansion Models: Literature Review and Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, P.; Eurek, K.; Margolis, R.

2014-07-01

Because solar power is a rapidly growing component of the electricity system, robust representations of solar technologies should be included in capacity-expansion models. This is a challenge because modeling the electricity system--and, in particular, modeling solar integration within that system--is a complex endeavor. This report highlights the major challenges of incorporating solar technologies into capacity-expansion models and shows examples of how specific models address those challenges. These challenges include modeling non-dispatchable technologies, determining which solar technologies to model, choosing a spatial resolution, incorporating a solar resource assessment, and accounting for solar generation variability and uncertainty.

Vertically integrated photonic multichip module architecture for vision applications

NASA Astrophysics Data System (ADS)

Tanguay, Armand R., Jr.; Jenkins, B. Keith; von der Malsburg, Christoph; Mel, Bartlett; Holt, Gary; O'Brien, John D.; Biederman, Irving; Madhukar, Anupam; Nasiatka, Patrick; Huang, Yunsong

2000-05-01

The development of a truly smart camera, with inherent capability for low latency semi-autonomous object recognition, tracking, and optimal image capture, has remained an elusive goal notwithstanding tremendous advances in the processing power afforded by VLSI technologies. These features are essential for a number of emerging multimedia- based applications, including enhanced augmented reality systems. Recent advances in understanding of the mechanisms of biological vision systems, together with similar advances in hybrid electronic/photonic packaging technology, offer the possibility of artificial biologically-inspired vision systems with significantly different, yet complementary, strengths and weaknesses. We describe herein several system implementation architectures based on spatial and temporal integration techniques within a multilayered structure, as well as the corresponding hardware implementation of these architectures based on the hybrid vertical integration of multiple silicon VLSI vision chips by means of dense 3D photonic interconnections.

Short-term spatial and temporal variability in greenhouse gas fluxes in riparian zones.

PubMed

Vidon, P; Marchese, S; Welsh, M; McMillan, S

2015-08-01

Recent research indicates that riparian zones have the potential to contribute significant amounts of greenhouse gases (GHG: N2O, CO2, CH4) to the atmosphere. Yet, the short-term spatial and temporal variability in GHG emission in these systems is poorly understood. Using two transects of three static chambers at two North Carolina agricultural riparian zones (one restored, one unrestored), we show that estimates of the average GHG flux at the site scale can vary by one order of magnitude depending on whether the mean or the median is used as a measure of central tendency. Because the median tends to mute the effect of outlier points (hot spots and hot moments), we propose that both must be reported or that other more advanced spatial averaging techniques (e.g., kriging, area-weighted average) should be used to estimate GHG fluxes at the site scale. Results also indicate that short-term temporal variability in GHG fluxes (a few days) under seemingly constant temperature and hydrological conditions can be as large as spatial variability at the site scale, suggesting that the scientific community should rethink sampling protocols for GHG at the soil-atmosphere interface to include repeated measures over short periods of time at select chambers to estimate GHG emissions in the field. Although recent advances in technology provide tools to address these challenges, their cost is often too high for widespread implementation. Until technology improves, sampling design strategies will need to be carefully considered to balance cost, time, and spatial and temporal representativeness of measurements.

Toward critical spatial thinking in the social sciences and humanities.

PubMed

Goodchild, Michael F; Janelle, Donald G

2010-02-01

The integration of geographically referenced information into the conceptual frameworks and applied uses of the social sciences and humanities has been an ongoing process over the past few centuries. It has gained momentum in recent decades with advances in technologies for computation and visualization and with the arrival of new data sources. This article begins with an overview of this transition, and argues that the spatial integration of information resources and the cross-disciplinary sharing of analysis and representation methodologies are important forces for the integration of scientific and artistic expression, and that they draw on core concepts in spatial (and spatio-temporal) thinking. We do not suggest that this is akin to prior concepts of unified knowledge systems, but we do maintain that the boundaries to knowledge transfer are disintegrating and that our abilities in problem solving for purposes of artistic expression and scientific development are enhanced through spatial perspectives. Moreover, approaches to education at all levels must recognize the need to impart proficiency in the critical and efficient application of these fundamental spatial concepts, if students and researchers are to make use of expanding access to a broadening range of spatialized information and data processing technologies.

An advanced scanning method for space-borne hyper-spectral imaging system

NASA Astrophysics Data System (ADS)

Wang, Yue-ming; Lang, Jun-Wei; Wang, Jian-Yu; Jiang, Zi-Qing

2011-08-01

Space-borne hyper-spectral imagery is an important means for the studies and applications of earth science. High cost efficiency could be acquired by optimized system design. In this paper, an advanced scanning method is proposed, which contributes to implement both high temporal and spatial resolution imaging system. Revisit frequency and effective working time of space-borne hyper-spectral imagers could be greatly improved by adopting two-axis scanning system if spatial resolution and radiometric accuracy are not harshly demanded. In order to avoid the quality degradation caused by image rotation, an idea of two-axis rotation has been presented based on the analysis and simulation of two-dimensional scanning motion path and features. Further improvement of the imagers' detection ability under the conditions of small solar altitude angle and low surface reflectance can be realized by the Ground Motion Compensation on pitch axis. The structure and control performance are also described. An intelligent integration technology of two-dimensional scanning and image motion compensation is elaborated in this paper. With this technology, sun-synchronous hyper-spectral imagers are able to pay quick visit to hot spots, acquiring both high spatial and temporal resolution hyper-spectral images, which enables rapid response of emergencies. The result has reference value for developing operational space-borne hyper-spectral imagers.

Broad frequency band full field measurements for advanced applications: Point-wise comparisons between optical technologies

NASA Astrophysics Data System (ADS)

Zanarini, Alessandro

2018-01-01

The progress of optical systems gives nowadays at disposal on lightweight structures complex dynamic measurements and modal tests, each with its own advantages, drawbacks and preferred usage domains. It is thus more easy than before to obtain highly spatially defined vibration patterns for many applications in vibration engineering, testing and general product development. The potential of three completely different technologies is here benchmarked on a common test rig and advanced applications. SLDV, dynamic ESPI and hi-speed DIC are here first deployed in a complex and unique test on the estimation of FRFs with high spatial accuracy from a thin vibrating plate. The latter exhibits a broad band dynamics and high modal density in the common frequency domain where the techniques can find an operative intersection. A peculiar point-wise comparison is here addressed by means of discrete geometry transforms to put all the three technologies on trial at each physical point of the surface. Full field measurement technologies cannot estimate only displacement fields on a refined grid, but can exploit the spatial consistency of the results through neighbouring locations by means of numerical differentiation operators in the spatial domain to obtain rotational degrees of freedom and superficial dynamic strain distributions, with enhanced quality, compared to other technologies in literature. Approaching the task with the aid of superior quality receptance maps from the three different full field gears, this work calculates and compares rotational and dynamic strain FRFs. Dynamic stress FRFs can be modelled directly from the latter, by means of a constitutive model, avoiding the costly and time-consuming steps of building and tuning a numerical dynamic model of a flexible component or a structure in real life conditions. Once dynamic stress FRFs are obtained, spectral fatigue approaches can try to predict the life of a component in many excitation conditions. Different spectral shaping of the excitation can easily be used to enhance the comparison in the framework of any of the spectral approaches for fatigue life calculations, highlighting benefits and drawbacks of a direct experimental approach to failure and risk assessment in structural dynamics when dealing with complex patterns in real-life testing. Are optical measurements and spatially dense datasets really effective in advanced model updating of lightweight structures with complex structural dynamics? The noise shown in the raw signal of some experiments may pose issues in proficiently exploiting the added data in a fruitful model updating procedure. Model updating results are here compared between scanning and native full field technologies, with comments and details on the test rig, on the advantages and drawbacks of the approaches. The identification of EMA models highlights the increasing quality of shapes that can be obtained from native full field high resolution gears, against that (some time unexpectedly poor) of SLDV tested.

Advanced Wavefront Control Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olivier, S S; Brase, J M; Avicola, K

2001-02-21

Programs at LLNL that involve large laser systems--ranging from the National Ignition Facility to new tactical laser weapons--depend on the maintenance of laser beam quality through precise control of the optical wavefront. This can be accomplished using adaptive optics, which compensate for time-varying aberrations that are often caused by heating in a high-power laser system. Over the past two decades, LLNL has developed a broad capability in adaptive optics technology for both laser beam control and high-resolution imaging. This adaptive optics capability has been based on thin deformable glass mirrors with individual ceramic actuators bonded to the back. In themore » case of high-power lasers, these adaptive optics systems have successfully improved beam quality. However, as we continue to extend our applications requirements, the existing technology base for wavefront control cannot satisfy them. To address this issue, this project studied improved modeling tools to increase our detailed understanding of the performance of these systems, and evaluated novel approaches to low-order wavefront control that offer the possibility of reduced cost and complexity. We also investigated improved beam control technology for high-resolution wavefront control. Many high-power laser systems suffer from high-spatial-frequency aberrations that require control of hundreds or thousands of phase points to provide adequate correction. However, the cost and size of current deformable mirrors can become prohibitive for applications requiring more than a few tens of phase control points. New phase control technologies are becoming available which offer control of many phase points with small low-cost devices. The goal of this project was to expand our wavefront control capabilities with improved modeling tools, new devices that reduce system cost and complexity, and extensions to high spatial and temporal frequencies using new adaptive optics technologies. In FY 99, the second year of this project, work was performed in four areas (1) advanced modeling tools for deformable mirrors (2) low-order wavefront correctors with Alvarez lenses, (3) a direct phase measuring heterdyne wavefront sensor, and (4) high-spatial-frequency wavefront control using spatial light modulators.« less

Recent Developments in PET Instrumentation

PubMed Central

Peng, Hao; Levin, Craig S.

2013-01-01

Positron emission tomography (PET) is used in the clinic and in vivo small animal research to study molecular processes associated with diseases such as cancer, heart disease, and neurological disorders, and to guide the discovery and development of new treatments. This paper reviews current challenges of advancing PET technology and some of newly developed PET detectors and systems. The paper focuses on four aspects of PET instrumentation: high photon detection sensitivity; improved spatial resolution; depth-of-interaction (DOI) resolution and time-of-flight (TOF). Improved system geometry, novel non-scintillator based detectors, and tapered scintillation crystal arrays are able to enhance the photon detection sensitivity of a PET system. Several challenges for achieving high resolution with standard scintillator-based PET detectors are discussed. Novel detectors with 3-D positioning capability have great potential to be deployed in PET for achieving spatial resolution better than 1 mm, such as cadmium-zinc-telluride (CZT) and position-sensitive avalanche photodiodes (PSAPDs). DOI capability enables a PET system to mitigate parallax error and achieve uniform spatial resolution across the field-of-view (FOV). Six common DOI designs, as well as advantages and limitations of each design, are discussed. The availability of fast scintillation crystals such as LaBr3, and the silicon photomultiplier (SiPM) greatly advances TOF-PET development. Recent instrumentation and initial results of clinical trials are briefly presented. If successful, these technology advances, together with new probe molecules, will substantially enhance the molecular sensitivity of PET and thus increase its role in preclinical and clinical research as well as evaluating and managing disease in the clinic. PMID:20497121

Laser-combined scanning tunnelling microscopy for probing ultrafast transient dynamics.

PubMed

Terada, Yasuhiko; Yoshida, Shoji; Takeuchi, Osamu; Shigekawa, Hidemi

2010-07-07

The development of time-resolved scanning tunnelling microscopy (STM), in particular, attempts to combine STM with ultrafast laser technology, is reviewed with emphasis on observed physical quantities and spatiotemporal resolution. Ultrashort optical pulse technology has allowed us to observe transient phenomena in the femtosecond range, which, however, has the drawback of a relatively low spatial resolution due to the electromagnetic wavelength used. In contrast, STM and its related techniques, although the time resolution is limited by the circuit bandwidth (∼100 kHz), enable us to observe structures at the atomic level in real space. Our purpose has been to combine these two techniques to achieve a new technology that satisfies the requirements for exploring the ultrafast transient dynamics of the local quantum functions in organized small structures, which will advance the pursuit of future nanoscale scientific research in terms of the ultimate temporal and spatial resolutions. © 2010 IOP Publishing Ltd

Microchannel plate detector technology potential for LUVOIR and HabEx

NASA Astrophysics Data System (ADS)

Siegmund, O. H. W.; Ertley, C.; Vallerga, J. V.; Schindhelm, E. R.; Harwit, A.; Fleming, B. T.; France, K. C.; Green, J. C.; McCandliss, S. R.; Harris, W. M.

2017-08-01

Microchannel plate (MCP) detectors have been the detector of choice for ultraviolet (UV) instruments onboard many NASA missions. These detectors have many advantages, including high spatial resolution (<20 μm), photon counting, radiation hardness, large formats (up to 20 cm), and ability for curved focal plane matching. Novel borosilicate glass MCPs with atomic layer deposition combine extremely low backgrounds, high strength, and tunable secondary electron yield. GaN and combinations of bialkali/alkali halide photocathodes show promise for broadband, higher quantum efficiency. Cross-strip anodes combined with compact ASIC readout electronics enable high spatial resolution over large formats with high dynamic range. The technology readiness levels of these technologies are each being advanced through research grants for laboratory testing and rocket flights. Combining these capabilities would be ideal for UV instruments onboard the Large UV/Optical/IR Surveyor (LUVOIR) and the Habitable Exoplanet Imaging Mission (HABEX) concepts currently under study for NASA's Astrophysics Decadal Survey.

Monitoring Science and Technology Symposium: Unifying Knowledge for Sustainability in the Western Hemisphere

Treesearch

C. Aguirre-Bravo; Patrick J. Pellicane; Denver P. Burns; Sidney Draggan

2006-01-01

A rational approach to monitoring and assessment is prerequisite for sustainable management of ecosystem resources. This features innovative ways to advance the concept of monitoring ecosystem sustainability across spheres of environmental concern, natural and anthropogenic processes, and other hemispheric issues over a variety of spatial scales and resolution levels....

Testing of a Stacked Core Mirror for UV Applications

NASA Technical Reports Server (NTRS)

Matthews, Gary W.; Kirk, Charles S.; Maffett, Steven P.; Abplanalp, Calvin E.; Stahl, H. Philip; Eng, Ron; Arnold, William R. Sr.

2013-01-01

Advanced Ultraviolet, Optical, Near-Infrared (UVOIR) Mirror Technology Development (AMTD) Testing Summary: (1) Processing of the stacked core mirror converged very quickly using ion figuring. (2) Results show no significant PSD change due to ion figuring in spatial periods smaller than 20mm. (3) Global surface figure limited by mount repeatability

Integrated remote sensing and visualization (IRSV) system for transportation infrastructure operations and management, phase two, volume 3 : advanced consideration in LiDAR technology for bridge evaluation.

DOT National Transportation Integrated Search

2012-03-01

This report describes Phase Two enhancement of terrestrial LiDAR scanning for bridge damage : evaluation that was initially developed in Phase One. Considering the spatial and reflectivity : information contained in LiDAR scans, two detection algorit...

Remote sensing and the Mississippi high accuracy reference network

NASA Technical Reports Server (NTRS)

Mick, Mark; Alexander, Timothy M.; Woolley, Stan

1994-01-01

Since 1986, NASA's Commercial Remote Sensing Program (CRSP) at Stennis Space Center has supported commercial remote sensing partnerships with industry. CRSP's mission is to maximize U.S. market exploitation of remote sensing and related space-based technologies and to develop advanced technical solutions for spatial information requirements. Observation, geolocation, and communications technologies are converging and their integration is critical to realize the economic potential for spatial informational needs. Global positioning system (GPS) technology enables a virtual revolution in geopositionally accurate remote sensing of the earth. A majority of states are creating GPS-based reference networks, or high accuracy reference networks (HARN). A HARN can be defined for a variety of local applications and tied to aerial or satellite observations to provide an important contribution to geographic information systems (GIS). This paper details CRSP's experience in the design and implementation of a HARN in Mississippi and the design and support of future applications of integrated earth observations, geolocation, and communications technology.

Contrast medium administration and image acquisition parameters in renal CT angiography: what radiologists need to know.

PubMed

Saade, Charbel; Deeb, Ibrahim Alsheikh; Mohamad, Maha; Al-Mohiy, Hussain; El-Merhi, Fadi

2016-01-01

Over the last decade, exponential advances in computed tomography (CT) technology have resulted in improved spatial and temporal resolution. Faster image acquisition enabled renal CT angiography to become a viable and effective noninvasive alternative in diagnosing renal vascular pathologies. However, with these advances, new challenges in contrast media administration have emerged. Poor synchronization between scanner and contrast media administration have reduced the consistency in image quality with poor spatial and contrast resolution. Comprehensive understanding of contrast media dynamics is essential in the design and implementation of contrast administration and image acquisition protocols. This review includes an overview of the parameters affecting renal artery opacification and current protocol strategies to achieve optimal image quality during renal CT angiography with iodinated contrast media, with current safety issues highlighted.

Advances in two photon scanning and scanless microscopy technologies for functional neural circuit imaging.

PubMed

Schultz, Simon R; Copeland, Caroline S; Foust, Amanda J; Quicke, Peter; Schuck, Renaud

2017-01-01

Recent years have seen substantial developments in technology for imaging neural circuits, raising the prospect of large scale imaging studies of neural populations involved in information processing, with the potential to lead to step changes in our understanding of brain function and dysfunction. In this article we will review some key recent advances: improved fluorophores for single cell resolution functional neuroimaging using a two photon microscope; improved approaches to the problem of scanning active circuits; and the prospect of scanless microscopes which overcome some of the bandwidth limitations of current imaging techniques. These advances in technology for experimental neuroscience have in themselves led to technical challenges, such as the need for the development of novel signal processing and data analysis tools in order to make the most of the new experimental tools. We review recent work in some active topics, such as region of interest segmentation algorithms capable of demixing overlapping signals, and new highly accurate algorithms for calcium transient detection. These advances motivate the development of new data analysis tools capable of dealing with spatial or spatiotemporal patterns of neural activity, that scale well with pattern size.

Advances in two photon scanning and scanless microscopy technologies for functional neural circuit imaging

PubMed Central

Schultz, Simon R.; Copeland, Caroline S.; Foust, Amanda J.; Quicke, Peter; Schuck, Renaud

2017-01-01

Recent years have seen substantial developments in technology for imaging neural circuits, raising the prospect of large scale imaging studies of neural populations involved in information processing, with the potential to lead to step changes in our understanding of brain function and dysfunction. In this article we will review some key recent advances: improved fluorophores for single cell resolution functional neuroimaging using a two photon microscope; improved approaches to the problem of scanning active circuits; and the prospect of scanless microscopes which overcome some of the bandwidth limitations of current imaging techniques. These advances in technology for experimental neuroscience have in themselves led to technical challenges, such as the need for the development of novel signal processing and data analysis tools in order to make the most of the new experimental tools. We review recent work in some active topics, such as region of interest segmentation algorithms capable of demixing overlapping signals, and new highly accurate algorithms for calcium transient detection. These advances motivate the development of new data analysis tools capable of dealing with spatial or spatiotemporal patterns of neural activity, that scale well with pattern size. PMID:28757657

Plant-based Food and Feed Protein Structure Changes Induced by Gene-transformation heating and bio-ethanol processing: A Synchrotron-based Molecular Structure and Nutrition Research Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

P Yu

Unlike traditional 'wet' analytical methods which during processing for analysis often result in destruction or alteration of the intrinsic protein structures, advanced synchrotron radiation-based Fourier transform infrared microspectroscopy has been developed as a rapid and nondestructive and bioanalytical technique. This cutting-edge synchrotron-based bioanalytical technology, taking advantages of synchrotron light brightness (million times brighter than sun), is capable of exploring the molecular chemistry or structure of a biological tissue without destruction inherent structures at ultra-spatial resolutions. In this article, a novel approach is introduced to show the potential of the advanced synchrotron-based analytical technology, which can be used to study plant-basedmore » food or feed protein molecular structure in relation to nutrient utilization and availability. Recent progress was reported on using synchrotron-based bioanalytical technique synchrotron radiation-based Fourier transform infrared microspectroscopy and diffused reflectance infrared Fourier transform spectroscopy to detect the effects of gene-transformation (Application 1), autoclaving (Application 2), and bio-ethanol processing (Application 3) on plant-based food and feed protein structure changes on a molecular basis. The synchrotron-based technology provides a new approach for plant-based protein structure research at ultra-spatial resolutions at cellular and molecular levels.« less

Challenges of Remote Sensing and Spatial Information Education and Technology Transfer in a Fast Developing Industry

NASA Astrophysics Data System (ADS)

Tsai, F.; Chen, L.-C.

2014-04-01

During the past decade, Taiwan has experienced an unusual and fast growing in the industry of mapping, remote sensing, spatial information and related markets. A successful space program and dozens of advanced airborne and ground-based remote sensing instruments as well as mobile mapping systems have been implemented and put into operation to support the vast demands of geospatial data acquisition. Moreover, in addition to the government agencies and research institutes, there are also tens of companies in the private sector providing geo-spatial data and services. However, the fast developing industry is also posing a great challenge to the education sector in Taiwan, especially the higher education for geo-spatial information. Facing this fast developing industry, the demands of skilled professionals and new technologies in order to address diversified needs are indubitably high. Consequently, while delighting in the expanding and prospering benefitted from the fast growing industry, how to fulfill these demands has become a challenge for the remote sensing and spatial information disciplines in the higher education institutes in Taiwan. This paper provides a brief insight into the status of the remote sensing and spatial information industry in Taiwan as well as the challenges of the education and technology transfer to support the increasing demands and to ensure the continuous development of the industry. In addition to the report of the current status of the remote sensing and spatial information related courses and programs in the colleges and universities, current and potential threatening issues and possible resolutions are also discussed in different points of view.

Generating structured light with phase helix and intensity helix using reflection-enhanced plasmonic metasurface at 2 μm

NASA Astrophysics Data System (ADS)

Zhao, Yifan; Du, Jing; Zhang, Jinrun; Shen, Li; Wang, Jian

2018-04-01

Mid-infrared (2-20 μm) light has been attracting great attention in many areas of science and technology. Beyond the extended wavelength range from visible and near-infrared to mid-infrared, shaping spatial structures may add opportunities to grooming applications of mid-infrared photonics. Here, we design and fabricate a reflection-enhanced plasmonic metasurface and demonstrate efficient generation of structured light with the phase helix and intensity helix at 2 μm. This work includes two distinct aspects. First, structured light (phase helix, intensity helix) generation at 2 μm, which is far beyond the ability of conventional spatial light modulators, is enabled by the metasurface with sub-wavelength engineered structures. Second, the self-referenced intensity helix against environmental noise is generated without using a spatially separated light. The demonstrations may open up advanced perspectives to structured light applications at 2 μm, such as phase helix for communications and non-communications (imaging, sensing) and intensity helix for enhanced microscopy and advanced metrology.

Rasdaman for Big Spatial Raster Data

NASA Astrophysics Data System (ADS)

Hu, F.; Huang, Q.; Scheele, C. J.; Yang, C. P.; Yu, M.; Liu, K.

2015-12-01

Spatial raster data have grown exponentially over the past decade. Recent advancements on data acquisition technology, such as remote sensing, have allowed us to collect massive observation data of various spatial resolution and domain coverage. The volume, velocity, and variety of such spatial data, along with the computational intensive nature of spatial queries, pose grand challenge to the storage technologies for effective big data management. While high performance computing platforms (e.g., cloud computing) can be used to solve the computing-intensive issues in big data analysis, data has to be managed in a way that is suitable for distributed parallel processing. Recently, rasdaman (raster data manager) has emerged as a scalable and cost-effective database solution to store and retrieve massive multi-dimensional arrays, such as sensor, image, and statistics data. Within this paper, the pros and cons of using rasdaman to manage and query spatial raster data will be examined and compared with other common approaches, including file-based systems, relational databases (e.g., PostgreSQL/PostGIS), and NoSQL databases (e.g., MongoDB and Hive). Earth Observing System (EOS) data collected from NASA's Atmospheric Scientific Data Center (ASDC) will be used and stored in these selected database systems, and a set of spatial and non-spatial queries will be designed to benchmark their performance on retrieving large-scale, multi-dimensional arrays of EOS data. Lessons learnt from using rasdaman will be discussed as well.

Application of GIS in public health in India: A literature-based review, analysis, and recommendations.

PubMed

Ruiz, Marilyn O'Hara; Sharma, Arun Kumar

2016-01-01

The implementation of geospatial technologies and methods for improving health has become widespread in many nations, but India's adoption of these approaches has been fairly slow. With a large population, ongoing public health challenges, and a growing economy with an emphasis on innovative technologies, the adoption of spatial approaches to disease surveillance, spatial epidemiology, and implementation of health policies in India has great potential for both success and efficacy. Through our evaluation of scientific papers selected through a structured key phrase review of the National Center for Biotechnology Information on the database PubMed, we found that current spatial approaches to health research in India are fairly descriptive in nature, but the use of more complex models and statistics is increasing. The institutional home of the authors is skewed regionally, with Delhi and South India more likely to show evidence of use. The need for scientists engaged in spatial health analysis to first digitize basic data, such as maps of road networks, hydrological features, and land use, is a strong impediment to efficiency, and their work would certainly advance more quickly without this requirement.

Recent Advances in Photonic Devices for Optical Computing and the Role of Nonlinear Optics-Part II

NASA Technical Reports Server (NTRS)

Abdeldayem, Hossin; Frazier, Donald O.; Witherow, William K.; Banks, Curtis E.; Paley, Mark S.

2007-01-01

The twentieth century has been the era of semiconductor materials and electronic technology while this millennium is expected to be the age of photonic materials and all-optical technology. Optical technology has led to countless optical devices that have become indispensable in our daily lives in storage area networks, parallel processing, optical switches, all-optical data networks, holographic storage devices, and biometric devices at airports. This chapters intends to bring some awareness to the state-of-the-art of optical technologies, which have potential for optical computing and demonstrate the role of nonlinear optics in many of these components. Our intent, in this Chapter, is to present an overview of the current status of optical computing, and a brief evaluation of the recent advances and performance of the following key components necessary to build an optical computing system: all-optical logic gates, adders, optical processors, optical storage, holographic storage, optical interconnects, spatial light modulators and optical materials.

High spatial resolution infrared camera as ISS external experiment

NASA Astrophysics Data System (ADS)

Eckehard, Lorenz; Frerker, Hap; Fitch, Robert Alan

High spatial resolution infrared camera as ISS external experiment for monitoring global climate changes uses ISS internal and external resources (eg. data storage). The optical experiment will consist of an infrared camera for monitoring global climate changes from the ISS. This technology was evaluated by the German small satellite mission BIRD and further developed in different ESA projects. Compared to BIRD the presended instrument uses proven sensor advanced technologies (ISS external) and ISS on board processing and storage capabili-ties (internal). The instrument will be equipped with a serial interfaces for TM/TC and several relay commands for the power supply. For data processing and storage a mass memory is re-quired. The access to actual attitude data is highly desired to produce geo referenced maps-if possible by an on board processing.

Possibilities and limitations of current stereo-endoscopy.

PubMed

Mueller-Richter, U D A; Limberger, A; Weber, P; Ruprecht, K W; Spitzer, W; Schilling, M

2004-06-01

Stereo-endoscopy has become a commonly used technology. In many comparative studies striking advantages of stereo-endoscopy over two-dimensional presentation could not be proven. To show the potential and fields for further improvement of this technology is the aim of this article. The physiological basis of three-dimensional vision limitations of current stereo-endoscopes is discussed and fields for further research are indicated. New developments in spatial picture acquisition and spatial picture presentation are discussed. Current limitations of stereo-endoscopy that prevent a better ranking in comparative studies with two-dimensional presentation are mainly based on insufficient picture acquisition. Devices for three-dimensional picture presentation are at a more advanced developmental stage than devices for three-dimensional picture acquisition. Further research should emphasize the development of new devices for three-dimensional picture acquisition.

Challenges of forest landscape modeling - simulating large landscapes and validating results

Treesearch

Hong S. He; Jian Yang; Stephen R. Shifley; Frank R. Thompson

2011-01-01

Over the last 20 years, we have seen a rapid development in the field of forest landscape modeling, fueled by both technological and theoretical advances. Two fundamental challenges have persisted since the inception of FLMs: (1) balancing realistic simulation of ecological processes at broad spatial and temporal scales with computing capacity, and (2) validating...

A Head in Virtual Reality: Development of A Dynamic Head and Neck Model

ERIC Educational Resources Information Center

Nguyen, Ngan; Wilson, Timothy D.

2009-01-01

Advances in computer and interface technologies have made it possible to create three-dimensional (3D) computerized models of anatomical structures for visualization, manipulation, and interaction in a virtual 3D environment. In the past few decades, a multitude of digital models have been developed to facilitate complex spatial learning of the…

Geostatistics, remote sensing and precision farming.

PubMed

Mulla, D J

1997-01-01

Precision farming is possible today because of advances in farming technology, procedures for mapping and interpolating spatial patterns, and geographic information systems for overlaying and interpreting several soil, landscape and crop attributes. The key component of precision farming is the map showing spatial patterns in field characteristics. Obtaining information for this map is often achieved by soil sampling. This approach, however, can be cost-prohibitive for grain crops. Soil sampling strategies can be simplified by use of auxiliary data provided by satellite or aerial photo imagery. This paper describes geostatistical methods for estimating spatial patterns in soil organic matter, soil test phosphorus and wheat grain yield from a combination of Thematic Mapper imaging and soil sampling.

μ-Rainbow: CdSe Nanocrystal Photoluminescence Gradients via Laser Spike Annealing for Kinetic Investigations and Tunable Device Design.

PubMed

Treml, Benjamin E; Jacobs, Alan G; Bell, Robert T; Thompson, Michael O; Hanrath, Tobias

2016-02-10

Much of the promise of nanomaterials derives from their size-dependent, and hence tunable, properties. Impressive advances have been made in the synthesis of nanoscale building blocks with precisely tailored size, shape and composition. Significant attention is now turning toward creating thin film structures in which size-dependent properties can be spatially programmed with high fidelity. Nonequilibrium processing techniques present exciting opportunities to create nanostructured thin films with unprecedented spatial control over their optical and electronic properties. Here, we demonstrate single scan laser spike annealing (ssLSA) on CdSe nanocrystal (NC) thin films as an experimental test bed to illustrate how the size-dependent photoluminescence (PL) emission can be tuned throughout the visible range and in spatially defined profiles during a single annealing step. Through control of the annealing temperature and time, we discovered that NC fusion is a kinetically limited process with a constant activation energy in over 2 orders of magnitude of NC growth rate. To underscore the broader technological implications of this work, we demonstrate the scalability of LSA to process large area NC films with periodically modulated PL emission, resulting in tunable emission properties of a large area film. New insights into the processing-structure-property relationships presented here offer significant advances in our fundamental understanding of kinetics of nanomaterials as well as technological implications for the production of nanomaterial films.

The Use of 3D Printing Technology in the Ilizarov Method Treatment: Pilot Study.

PubMed

Burzyńska, Karolina; Morasiewicz, Piotr; Filipiak, Jarosław

2016-01-01

Significant developments in additive manufacturing technology have occurred in recent years. 3D printing techniques can also be helpful in the Ilizarov method treatment. The aim of this study was to evaluate the usefulness of 3D printing technology in the Ilizarov method treatment. Physical models of bones used to plan the spatial design of Ilizarov external fixator were manufactured by FDM (Fused Deposition Modeling) spatial printing technology. Bone models were made of poly(L-lactide) (PLA). Printed 3D models of both lower leg bones allow doctors to prepare in advance for the Ilizarov method treatment: detailed consideration of the spatial configuration of the external fixation, experimental assembly of the Ilizarov external fixator onto the physical models of bones prior to surgery, planning individual osteotomy level and Kirschner wires introduction sites. Printed 3D bone models allow for accurate preparation of the Ilizarov apparatus spatially matched to the size of the bones and prospective bone distortion. Employment of the printed 3D models of bone will enable a more precise design of the apparatus, which is especially useful in multiplanar distortion and in the treatment of axis distortion and limb length discrepancy in young children. In the course of planning the use of physical models manufactured with additive technology, attention should be paid to certain technical aspects of model printing that have an impact on the accuracy of mapping of the geometry and physical properties of the model. 3D printing technique is very useful in 3D planning of the Ilizarov method treatment.

A small terminal for satellite communication systems

NASA Technical Reports Server (NTRS)

Xiong, Fuqin; Wu, Dong; Jin, Min

1994-01-01

A small portable, low-cost satellite communications terminal system incorporating a modulator/demodulator and convolutional-Viterbi coder/decoder is described. Advances in signal processing and error-correction techniques in combination with higher power and higher frequencies aboard satellites allow for more efficient use of the space segment. This makes it possible to design small economical earth stations. The Advanced Communications Technology Satellite (ACTS) was chosen to test the system. ACTS, operating at the Ka band incorporates higher power, higher frequency, frequency and spatial reuse using spot beams and polarization.

Sustainable Biosphere Initiative Project

NASA Technical Reports Server (NTRS)

1997-01-01

The goal of the Advanced Technology in Ecological Sciences project is to gain broad participation within the environmental scientific community in developing a research agenda addressing the development and refinement of technologies instrumental to research that responds to these challenges (e.g. global climate change, unsustainable resource use, and threats to biological diversity). The following activities have been completed: (1) A listserve 'eco-tech was set up to serve as a clearinghouse of information about activities and events relating to advanced technologies; (2) A series of conference calls were organized on specific topics including data visualization and spatial analysis, and remote sensing; and (3) Two meetings were organized at the 19% ESA Annual Meeting in Providence, Rhode Island. Topics covered included concerns about tool and data sharing; interest in expanded development of ground-based remote sensing technologies for monitoring; issues involved in training for using new technologies and increasing data streams, and- associated implications of data processing capabilities; questions about how to develop appropriate standards (i.e. surface morphology classification standards) that facilitate the exchange and comparison of analytical results; and some thoughts about remote sensing platforms and vehicles.

Ultra-spatial synchrotron radiation for imaging molecular chemical structure: Applications in plant and animal studies

DOE PAGES

Yu, Peiqiang

2007-01-01

Synchrotron-based Fourier transform infrared microspectroscopy (S-FTIR) has been developed as a rapid, direct, non-destructive, bioanalytical technique. This technique takes advantage of synchrotron light brightness and small effective source size and is capable of exploring the molecular chemical features and make-up within microstructures of a biological tissue without destruction of inherent structures at ultra-spatial resolutions within cellular dimension. To date there has been very little application of this advanced synchrotron technique to the study of plant and animal tissues' inherent structure at a cellular or subcellular level. In this article, a novel approach was introduced to show the potential of themore » newly developed, advanced synchrotron-based analytical technology, which can be used to reveal molecular structural-chemical features of various plant and animal tissues.« less

Contrast medium administration and image acquisition parameters in renal CT angiography: what radiologists need to know

PubMed Central

Saade, Charbel; Deeb, Ibrahim Alsheikh; Mohamad, Maha; Al-Mohiy, Hussain; El-Merhi, Fadi

2016-01-01

Over the last decade, exponential advances in computed tomography (CT) technology have resulted in improved spatial and temporal resolution. Faster image acquisition enabled renal CT angiography to become a viable and effective noninvasive alternative in diagnosing renal vascular pathologies. However, with these advances, new challenges in contrast media administration have emerged. Poor synchronization between scanner and contrast media administration have reduced the consistency in image quality with poor spatial and contrast resolution. Comprehensive understanding of contrast media dynamics is essential in the design and implementation of contrast administration and image acquisition protocols. This review includes an overview of the parameters affecting renal artery opacification and current protocol strategies to achieve optimal image quality during renal CT angiography with iodinated contrast media, with current safety issues highlighted. PMID:26728701

Public health, GIS, and the internet.

PubMed

Croner, Charles M

2003-01-01

Internet access and use of georeferenced public health information for GIS application will be an important and exciting development for the nation's Department of Health and Human Services and other health agencies in this new millennium. Technological progress toward public health geospatial data integration, analysis, and visualization of space-time events using the Web portends eventual robust use of GIS by public health and other sectors of the economy. Increasing Web resources from distributed spatial data portals and global geospatial libraries, and a growing suite of Web integration tools, will provide new opportunities to advance disease surveillance, control, and prevention, and insure public access and community empowerment in public health decision making. Emerging supercomputing, data mining, compression, and transmission technologies will play increasingly critical roles in national emergency, catastrophic planning and response, and risk management. Web-enabled public health GIS will be guided by Federal Geographic Data Committee spatial metadata, OpenGIS Web interoperability, and GML/XML geospatial Web content standards. Public health will become a responsive and integral part of the National Spatial Data Infrastructure.

A new concept for spatially divided Deep Reactive Ion Etching with ALD-based passivation

NASA Astrophysics Data System (ADS)

Roozeboom, F.; Kniknie, B.; Lankhorst, A. M.; Winands, G.; Knaapen, R.; Smets, M.; Poodt, P.; Dingemans, G.; Keuning, W.; Kessels, W. M. M.

2012-12-01

Conventional Deep Reactive Ion Etching (DRIE) is a plasma etch process with alternating half-cycles of 1) Si-etching with SF6 to form gaseous SiFx etch products, and 2) passivation with C4F8 that polymerizes as a protecting fluorocarbon deposit on the sidewalls and bottom of the etched features. In this work we report on a novel alternative and disruptive technology concept of Spatially-divided Deep Reactive Ion Etching, S-DRIE, where the process is converted from the time-divided into the spatially divided regime. The spatial division can be accomplished by inert gas bearing 'curtains' of heights down to ~20 μm. These curtains confine the reactive gases to individual (often linear) injection slots constructed in a gas injector head. By horizontally moving the substrate back and forth under the head one can realize the alternate exposures to the overall cycle. A second improvement in the spatially divided approach is the replacement of the CVD-based C4F8 passivation steps by ALD-based oxide (e.g. SiO2) deposition cycles. The method can have industrial potential in cost-effective creation of advanced 3D interconnects (TSVs), MEMS manufacturing and advanced patterning, e.g., in nanoscale transistor line edge roughness using Atomic Layer Etching.

Advanced Compact Holographic Data Storage System

NASA Technical Reports Server (NTRS)

Chao, Tien-Hsin; Zhou, Hanying; Reyes, George

2000-01-01

JPL, under current sponsorship from NASA Space Science and Earth Science Programs, is developing a high-density, nonvolatile and rad-hard Advanced Holographic Memory (AHM) system to enable large-capacity, high-speed, low power consumption, and read/write of data in a space environment. The entire read/write operation will be controlled with electro-optic mechanism without any moving parts. This CHDS will consist of laser diodes, photorefractive crystal, spatial light modulator, photodetector array, and I/O electronic interface. In operation, pages of information would be recorded and retrieved with random access and highspeed. The nonvolatile, rad-hard characteristics of the holographic memory will provide a revolutionary memory technology to enhance mission capabilities for all NASA's Earth Science Mission. In this paper, recent technology progress in developing this CHDS at JPL will be presented.

An innovative computer design for modeling forest landscape change in very large spatial extents with fine resolutions

Treesearch

Jian Yang; Hong S. He; Stephen R. Shifley; Frank R. Thompson; Yangjian Zhang

2011-01-01

Although forest landscape models (FLMs) have benefited greatly from ongoing advances of computer technology and software engineering, computing capacity remains a bottleneck in the design and development of FLMs. Computer memory overhead and run time efficiency are primary limiting factors when applying forest landscape models to simulate large landscapes with fine...

Application of Advanced Sensor Technology to DoD Soil Vapor Intrusion Problems

DTIC Science & Technology

2012-10-01

19 Figure 10. Photographs of: a) Layton , Utah, ASU SERDP project study house and b) basement...relative to sub-slab; line). ..................... 24 Figure 18. Spatial distributions of TCE in Layton , Utah, house without VI and emplaced indoor...technical advice and use of ASU’s Strategic Environmental Research and Development Program (SERDP) VI study house in Layton , Utah, is very

Thermal Characterization of Defects in Aircraft Structures Via Spatially Controlled Heat Application

NASA Technical Reports Server (NTRS)

Cramer, K. Elliott; Winfree, William P.

1997-01-01

Recent advances in thermal imaging technology have spawned a number of new thermal NDE techniques that provide quantitative information about flaws in aircraft structures. Thermography has a number of advantages as an inspection technique. It is a totally noncontacting, nondestructive, imaging technology capable of inspecting a large area in a matter of a few seconds. The development of fast, inexpensive image processors have aided in the attractiveness of thermography as an NDE technique. These image processors have increased the signal to noise ratio of thermography and facilitated significant advances in post-processing. The resulting digital images enable archival records for comparison with later inspections thus providing a means of monitoring the evolution of damage in a particular structure. The National Aeronautics and Space Administration's Langley Research Center has developed a thermal NDE technique designed to image a number of potential flaws in aircraft structures. The technique involves injecting a small, spatially controlled heat flux into the outer surface of an aircraft. Images of fatigue cracking, bond integrity and material loss due to corrosion are generated from measurements of the induced surface temperature variations. This paper will present a discussion of the development of the thermal imaging system as well as the techniques used to analyze the resulting thermal images. Spatial tailoring of the heat coupled with the analysis techniques represent a significant improvement in the delectability of flaws over conventional thermal imaging. Results of laboratory experiments on fabricated crack, disbond and material loss samples will be presented to demonstrate the capabilities of the technique. An integral part of the development of this technology is the use of analytic and computational modeling. The experimental results will be compared with these models to demonstrate the utility of such an approach.

Overview and Summary of the Advanced Mirror Technology Development Project

NASA Astrophysics Data System (ADS)

Stahl, H. P.

2014-01-01

Advanced Mirror Technology Development (AMTD) is a NASA Strategic Astrophysics Technology project to mature to TRL-6 the critical technologies needed to produce 4-m or larger flight-qualified UVOIR mirrors by 2018 so that a viable mission can be considered by the 2020 Decadal Review. The developed mirror technology must enable missions capable of both general astrophysics & ultra-high contrast observations of exoplanets. Just as JWST’s architecture was driven by launch vehicle, a future UVOIR mission’s architectures (monolithic, segmented or interferometric) will depend on capacities of future launch vehicles (and budget). Since we cannot predict the future, we must prepare for all potential futures. Therefore, to provide the science community with options, we are pursuing multiple technology paths. AMTD uses a science-driven systems engineering approach. We derived engineering specifications for potential future monolithic or segmented space telescopes based on science needs and implement constraints. And we are maturing six inter-linked critical technologies to enable potential future large aperture UVOIR space telescope: 1) Large-Aperture, Low Areal Density, High Stiffness Mirrors, 2) Support Systems, 3) Mid/High Spatial Frequency Figure Error, 4) Segment Edges, 5) Segment-to-Segment Gap Phasing, and 6) Integrated Model Validation Science Advisory Team and a Systems Engineering Team. We are maturing all six technologies simultaneously because all are required to make a primary mirror assembly (PMA); and, it is the PMA’s on-orbit performance which determines science return. PMA stiffness depends on substrate and support stiffness. Ability to cost-effectively eliminate mid/high spatial figure errors and polishing edges depends on substrate stiffness. On-orbit thermal and mechanical performance depends on substrate stiffness, the coefficient of thermal expansion (CTE) and thermal mass. And, segment-to-segment phasing depends on substrate & structure stiffness. This presentation will introduce the goals and objectives of the AMTD project and summarize its recent accomplishments.

Towards artificial tissue models: past, present, and future of 3D bioprinting.

PubMed

Arslan-Yildiz, Ahu; El Assal, Rami; Chen, Pu; Guven, Sinan; Inci, Fatih; Demirci, Utkan

2016-03-01

Regenerative medicine and tissue engineering have seen unprecedented growth in the past decade, driving the field of artificial tissue models towards a revolution in future medicine. Major progress has been achieved through the development of innovative biomanufacturing strategies to pattern and assemble cells and extracellular matrix (ECM) in three-dimensions (3D) to create functional tissue constructs. Bioprinting has emerged as a promising 3D biomanufacturing technology, enabling precise control over spatial and temporal distribution of cells and ECM. Bioprinting technology can be used to engineer artificial tissues and organs by producing scaffolds with controlled spatial heterogeneity of physical properties, cellular composition, and ECM organization. This innovative approach is increasingly utilized in biomedicine, and has potential to create artificial functional constructs for drug screening and toxicology research, as well as tissue and organ transplantation. Herein, we review the recent advances in bioprinting technologies and discuss current markets, approaches, and biomedical applications. We also present current challenges and provide future directions for bioprinting research.

Significant advancement of mass spectrometry imaging for food chemistry.

PubMed

Yoshimura, Yukihiro; Goto-Inoue, Naoko; Moriyama, Tatsuya; Zaima, Nobuhiro

2016-11-01

Food contains various compounds that have an impact on our daily lives. Many technologies have been established to analyze these molecules of interest in foods. However, the analysis of the spatial distribution of these compounds in foods using conventional technology, such as high-performance liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is considered an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. MALDI-MSI can be used to visualize the spatial distribution of chemical compounds or biomolecules in foods. Although the methodology of MALDI-MSI in food science is not yet fully established, the versatility of MALDI-MSI is expected to open a new frontier in food science. Herein, we describe the principles and applications of MALDI-MSI in food science and related fields. Copyright © 2016 Elsevier Ltd. All rights reserved.

NATO Advanced Study Institute on Spectroscopy

NASA Technical Reports Server (NTRS)

DiBartolo, Baldassare; Barnes, James (Technical Monitor)

2001-01-01

This booklet presents an account of the course 'Spectroscopy of Systems with Spatially Confined Structures' held in Erice-Sicily, Italy, from June 15 to June 30, 2001. This meeting was organized by the International School of Atomic and Molecular Spectroscopy of the 'Ettore Majorana' Centre for Scientific Culture. The purpose of this course was to present and discuss nanometer-scale physics, a rapidly progressing field. The top-down approach of semiconductor technology will soon meet the scales of the bottom-up approaches of supramolecular chemistry and of spatially localized excitations in ionic crystals. This course dealt with the fabrication, measurement and understanding of the relevant structures and brought together the scientific communities responsible for these development. The advances in this area of physics have already let to applications in optoelectronics and will likely lead to many more. The subjects of the course included spatially resolved structures such as quantum wells, quantum wires and quantum dots, single atoms and molecules, clusters, fractal systems, and the development of related techniques like near-field spectroscopy and confocal microscopy to study such systems.

Spatial Relation Predicates in Topographic Feature Semantics

USGS Publications Warehouse

Varanka, Dalia E.; Caro, Holly K.

2013-01-01

Topographic data are designed and widely used for base maps of diverse applications, yet the power of these information sources largely relies on the interpretive skills of map readers and relational database expert users once the data are in map or geographic information system (GIS) form. Advances in geospatial semantic technology offer data model alternatives for explicating concepts and articulating complex data queries and statements. To understand and enrich the vocabulary of topographic feature properties for semantic technology, English language spatial relation predicates were analyzed in three standard topographic feature glossaries. The analytical approach drew from disciplinary concepts in geography, linguistics, and information science. Five major classes of spatial relation predicates were identified from the analysis; representations for most of these are not widely available. The classes are: part-whole (which are commonly modeled throughout semantic and linked-data networks), geometric, processes, human intention, and spatial prepositions. These are commonly found in the ‘real world’ and support the environmental science basis for digital topographical mapping. The spatial relation concepts are based on sets of relation terms presented in this chapter, though these lists are not prescriptive or exhaustive. The results of this study make explicit the concepts forming a broad set of spatial relation expressions, which in turn form the basis for expanding the range of possible queries for topographical data analysis and mapping.

Exploring spatial evolution of economic clusters: A case study of Beijing

NASA Astrophysics Data System (ADS)

Yang, Zhenshan; Sliuzas, Richard; Cai, Jianming; Ottens, Henk F. L.

2012-10-01

An identification of economic clusters and analysing their changing spatial patterns is important for understanding urban economic space dynamics. Previous studies, however, suffer from limitations as a consequence of using fixed geographically areas and not combining functional and spatial dynamics. The paper presents an approach, based on local spatial statistics and the case of Beijing to understand the spatial clustering of industries that are functionally interconnected by common or complementary patterns of demand or supply relations. Using register data of business establishments, it identifies economic clusters and analyses their pattern based on postcodes at different time slices during the period 1983-2002. The study shows how the advanced services occupy the urban centre and key sub centres. The Information and Communication Technology (ICT) cluster is mainly concentrated in the north part of the city and circles the urban centre, and the main manufacturing clusters are evolved in the key sub centers. This type of outcomes improves understanding of urban-economic dynamics, which can support spatial and economic planning.

A review on technologies and their usage in solid waste monitoring and management systems: Issues and challenges.

PubMed

Hannan, M A; Abdulla Al Mamun, Md; Hussain, Aini; Basri, Hassan; Begum, R A

2015-09-01

In the backdrop of prompt advancement, information and communication technology (ICT) has become an inevitable part to plan and design of modern solid waste management (SWM) systems. This study presents a critical review of the existing ICTs and their usage in SWM systems to unfold the issues and challenges towards using integrated technologies based system. To plan, monitor, collect and manage solid waste, the ICTs are divided into four categories such as spatial technologies, identification technologies, data acquisition technologies and data communication technologies. The ICT based SWM systems classified in this paper are based on the first three technologies while the forth one is employed by almost every systems. This review may guide the reader about the basics of available ICTs and their application in SWM to facilitate the search for planning and design of a sustainable new system. Copyright © 2015 Elsevier Ltd. All rights reserved.

The study of precision measurement of pelvis spatial structure

NASA Astrophysics Data System (ADS)

Ma, Xiang; Ouyang, Jianfei; Qu, Xinghua

2010-03-01

Osteometry is fundamental for anthropometry. It provides the key technology and value to the study of palaeoanthropology, medicine, and criminal investigation. The traditional osteometry that has been widely accepted and used since 18th century has no longer met the information demand for modern research and application. It is significant and necessary to create an advanced 3-dimensional osteometry technique for anthropometry. This paper presents a new quick and accurate method to measure human pelvis through mathematical modeling. The pelvis is a complex combination of bones, which consists of three connected parts: hipbones, sacrum, and coccyx. There are over 40 items to be measured for the 1-dimension characteristics. In this paper, a combined measuring technology is developed for pelvis measurement. It uses machine vision systems and a portable measuring arm to obtain key geometry parameters of the pelvis. The mathematics models of the pelvis spatial structure and its parts are created through the process of data collecting, digging, assembling, and modeling. The experiment shows that the proposed technology can meet traditional osteometry and obtain entire 1D geometric parameters of the pelvis, such as maximum breadth and height, diameter of obstetric conjugata, inclination angle, and sakralneigungswinkel, etc. at the same time after modeling. Besides making the measurements above, the proposed technology can measure the geometry characteristics of pelvis and its parts, such as volume, surface area, curvature, and spatial structure, which are almost impossible for traditional technology. The overall measuring error is less than 0.1mm.

Evolution in High Spatial Resolution Imaging of Faint, Complex Objects

NASA Astrophysics Data System (ADS)

van Belle, G.

The astrophysical community has been working at the task of obtaining image information of the smallest structures in the sky via the use of optical interferometry for well over a century. A richly diverse family of technology architectures has been explored over the years, and yet the current family of facilities are all striking similar. Although there may be other, heretofore undeployed, architectures that support the goal of collecting image information at the highest resolutions, we expect dramatic advances at the component level of long-baseline interferometry to be the best avenue for advancing the technique, rather than entirely new architectures.

An update on intraoperative three-dimensional transesophageal echocardiography

PubMed Central

2017-01-01

Transesophageal echocardiography (TEE) was first used routinely in the operating rooms in the 1980s to facilitate surgical decision-making. Since then, TEE has evolved from the standard two-dimensional (2D) exam to include focused real-time three-dimensional (RT-3D) imaging both inside and outside the operating rooms. Improved spatial and temporal resolution due to technological advances has expedited surgical interventions in diseased valves. 3D imaging has also emerged as a crucial adjunct in percutaneous interventions for structural heart disease. With continued advancement in software, RT-3D TEE will continue to impact perioperative decisions. PMID:28540070

Geo-portal as a planning instrument: supporting decision making and fostering market potential of Energy efficiency in buildings

NASA Astrophysics Data System (ADS)

Cuca, Branka; Brumana, Raffaella; Oreni, Daniela; Iannaccone, Giuliana; Sesana, Marta Maria

2014-03-01

Steady technological progress has led to a noticeable advancement in disciplines associated with Earth observation. This has enabled information transition regarding changing scenarios, both natural and urban, to occur in (almost) real time. In particular, the need for integration on a local scale with the wider territorial framework has occurred in analysis and monitoring of built environments over the last few decades. The progress of Geographic Information (GI) science has provided significant advancements when it comes to spatial analysis, while the almost free availability of the internet has ensured a fast and constant exchange of geo-information, even for everyday users' requirements. Due to its descriptive and semantic nature, geo-spatial information is capable of providing a complete overview of a certain phenomenon and of predicting the implications within the natural, social and economic context. However, in order to integrate geospatial data into decision making processes, it is necessary to provide a specific context, which is well supported by verified data. This paper investigates the potentials of geo-portals as planning instruments developed to share multi-temporal/multi-scale spatial data, responding to specific end-users' demands in the case of Energy efficiency in Buildings (EeB) across European countries. The case study regards the GeoCluster geo-portal and mapping tool (Project GE2O, FP7), built upon a GeoClustering methodology for mapping of indicators relevant for energy efficiency technologies in the construction sector.

Computational Study of Thrombus Formation and Clotting Factor Effects under Venous Flow Conditions

DTIC Science & Technology

2016-04-26

Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MarylandABSTRACT A comprehensive... experimental study. The model allowed us to identify the distinct patterns character- izing the spatial distributions of thrombin, platelets, and fibrin...time, elevated fibrinogen levels may contribute to the development of thrombosis (4,6,12). Quantitative knowledge about the interactions between fibrin

Next-generation pushbroom filter radiometers for remote sensing

NASA Astrophysics Data System (ADS)

Tarde, Richard W.; Dittman, Michael G.; Kvaran, Geir E.

2012-09-01

Individual focal plane size, yield, and quality continue to improve, as does the technology required to combine these into large tiled formats. As a result, next-generation pushbroom imagers are replacing traditional scanning technologies in remote sensing applications. Pushbroom architecture has inherently better radiometric sensitivity and significantly reduced payload mass, power, and volume than previous generation scanning technologies. However, the architecture creates challenges achieving the required radiometric accuracy performance. Achieving good radiometric accuracy, including image spectral and spatial uniformity, requires creative optical design, high quality focal planes and filters, careful consideration of on-board calibration sources, and state-of-the-art ground test facilities. Ball Aerospace built the Landsat Data Continuity Mission (LDCM) next-generation Operational Landsat Imager (OLI) payload. Scheduled to launch in 2013, OLI provides imagery consistent with the historical Landsat spectral, spatial, radiometric, and geometric data record and completes the generational technology upgrade from the Enhanced Thematic Mapper (ETM+) whiskbroom technology to modern pushbroom technology afforded by advanced focal planes. We explain how Ball's capabilities allowed producing the innovative next-generational OLI pushbroom filter radiometer that meets challenging radiometric accuracy or calibration requirements. OLI will improve the multi-decadal land surface observation dataset dating back to the 1972 launch of ERTS-1 or Landsat 1.

Smart Sensors: Why and when the origin was and why and where the future will be

NASA Astrophysics Data System (ADS)

Corsi, C.

2013-12-01

Smart Sensors is a technique developed in the 70's when the processing capabilities, based on readout integrated with signal processing, was still far from the complexity needed in advanced IR surveillance and warning systems, because of the enormous amount of noise/unwanted signals emitted by operating scenario especially in military applications. The Smart Sensors technology was kept restricted within a close military environment exploding in applications and performances in the 90's years thanks to the impressive improvements in the integrated signal read-out and processing achieved by CCD-CMOS technologies in FPA. In fact the rapid advances of "very large scale integration" (VLSI) processor technology and mosaic EO detector array technology allowed to develop new generations of Smart Sensors with much improved signal processing by integrating microcomputers and other VLSI signal processors. inside the sensor structure achieving some basic functions of living eyes (dynamic stare, non-uniformity compensation, spatial and temporal filtering). New and future technologies (Nanotechnology, Bio-Organic Electronics, Bio-Computing) are lightning a new generation of Smart Sensors extending the Smartness from the Space-Time Domain to Spectroscopic Functional Multi-Domain Signal Processing. History and future forecasting of Smart Sensors will be reported.

Involving the public in spatial decision making using Internet GIS

NASA Astrophysics Data System (ADS)

Liu, Zhengrong; Sheng, Grant; Wang, Lei

2006-10-01

Public participation is an integral part of legislation or decision making processes. Traditionally, public participation took place through face-to-face encounters such as public meetings and other fora. However, some important factors limiting the efficiency and effectiveness of this mode of public participation include: geographic separation of participants, scheduling and financial constraints in attending meetings, and limited duration of meetings. These led to the awareness that public participation requires new methods in order to achieve a better democratic decision making. On the other hand, GIS has in the past been accused of being an elitist technology, giving more power to those people already possessing it and depriving those, namely the general public, who more often lack such direct forms of information access. Public participation GIS (PPGIS) is emerging as a distinct subset of two previously separate activities: technology-based spatial analysis and participatory democracy. The paper considers both traditional methods and Internet-based technologies of public participation and argues that new Internet-based technologies have the potential to widen participation by using online spatial decision support systems. GIS and the Internet can be used together to provide the general public with a powerful mechanism for becoming more involved in decision problems. Provision of full access to spatial and non-spatial data, along with the appropriate tools with which to use it, may greatly empower the general public. PPGIS focuses on engaging the public to participate and become involved in a particular subject of interest. It empowers GIS users from all walks of life and enabling them to use the technology purposefully to capture their local knowledge and advance their goals. In the project of public participatory Ontario nuclear waste siting, we focused on developing an Internet based PPGIS prototype to help the public to participate online from inception to the final phase of site decision-making. It shows that in certain siting problems and policy formulation processes, participatory online systems are a useful means of implementing public participation through informing and engaging the public to participate in spatial decision making. Web based PPGIS can involve more participants and higher degree of participation among experts, officials and the pblic than traditional means.

Beyond Moore's Law: Harnessing spatial-digital disruptive technologies for Digital Earth

NASA Astrophysics Data System (ADS)

Foresman, Timothy W.

2016-11-01

Moore's law will reach its plateau by 2020. Big data, however, will continue to increase as the Internet of Things and social media converge into the new era of ‘huge data’. Disruptive technologies, including big data and cloud computing are forces impacting business and government communities. The truth of our collective future is suggested to align with the Digital Earth (DE) vision. Benefits of technological advances will be manifested from business performance improvements based on capitalizing the locational attributes of corporate and government assets - the foundation of big data. Better governance and better business represents a key foundation for sustainability and therefore should be explicit DE guiding principles.

Development of black scattering coatings for space application (etude de traitements noirs diffusants pour application spatiale)

NASA Astrophysics Data System (ADS)

Mestreau-Garreau, Agnes; Pezant, Christian; Cousin, Bernard; Etcheto, Pierre; Otrio, Georges

2017-11-01

In the context of Research and Technology (R&T), studies have been performed on the coatings of vane edge in the 0.4 to 1 μm spectral range. The main purposes of the study were to improve the diffusing black coatings available on the market and to look for other diffusing black coatings. At the same time, we have also improved the machining technologies of vane edges. The characterisation (thermal tests, radiometric measurements, adhesion tests) of the most promising technologies has been carried out. The results have pointed out the stainless steel vanes with the edge obtained by polishing or by advanced grinding.

Geospatial Based Information System Development in Public Administration for Sustainable Development and Planning in Urban Environment

NASA Astrophysics Data System (ADS)

Kouziokas, Georgios N.

2016-09-01

It is generally agreed that the governmental authorities should actively encourage the development of an efficient framework of information and communication technology initiatives so as to advance and promote sustainable development and planning strategies. This paper presents a prototype Information System for public administration which was designed to facilitate public management and decision making for sustainable development and planning. The system was developed by using several programming languages and programming tools and also a Database Management System (DBMS) for storing and managing urban data of many kinds. Furthermore, geographic information systems were incorporated into the system in order to make possible to the authorities to deal with issues of spatial nature such as spatial planning. The developed system provides a technology based management of geospatial information, environmental and crime data of urban environment aiming at improving public decision making and also at contributing to a more efficient sustainable development and planning.

AFM-IR: Technology and Applications in Nanoscale Infrared Spectroscopy and Chemical Imaging.

PubMed

Dazzi, Alexandre; Prater, Craig B

2016-12-13

Atomic force microscopy-based infrared spectroscopy (AFM-IR) is a rapidly emerging technique that provides chemical analysis and compositional mapping with spatial resolution far below conventional optical diffraction limits. AFM-IR works by using the tip of an AFM probe to locally detect thermal expansion in a sample resulting from absorption of infrared radiation. AFM-IR thus can provide the spatial resolution of AFM in combination with the chemical analysis and compositional imaging capabilities of infrared spectroscopy. This article briefly reviews the development and underlying technology of AFM-IR, including recent advances, and then surveys a wide range of applications and investigations using AFM-IR. AFM-IR applications that will be discussed include those in polymers, life sciences, photonics, solar cells, semiconductors, pharmaceuticals, and cultural heritage. In the Supporting Information , the authors provide a theoretical section that reviews the physics underlying the AFM-IR measurement and detection mechanisms.

Spatial Information Processing: Standards-Based Open Source Visualization Technology

NASA Astrophysics Data System (ADS)

Hogan, P.

2009-12-01

. Spatial information intelligence is a global issue that will increasingly affect our ability to survive as a species. Collectively we must better appreciate the complex relationships that make life on Earth possible. Providing spatial information in its native context can accelerate our ability to process that information. To maximize this ability to process information, three basic elements are required: data delivery (server technology), data access (client technology), and data processing (information intelligence). NASA World Wind provides open source client and server technologies based on open standards. The possibilities for data processing and data sharing are enhanced by this inclusive infrastructure for geographic information. It is interesting that this open source and open standards approach, unfettered by proprietary constraints, simultaneously provides for entirely proprietary use of this same technology. 1. WHY WORLD WIND? NASA World Wind began as a single program with specific functionality, to deliver NASA content. But as the possibilities for virtual globe technology became more apparent, we found that while enabling a new class of information technology, we were also getting in the way. Researchers, developers and even users expressed their desire for World Wind functionality in ways that would service their specific needs. They want it in their web pages. They want to add their own features. They want to manage their own data. They told us that only with this kind of flexibility, could their objectives and the potential for this technology be truly realized. World Wind client technology is a set of development tools, a software development kit (SDK) that allows a software engineer to create applications requiring geographic visualization technology. 2. MODULAR COMPONENTRY Accelerated evolution of a technology requires that the essential elements of that technology be modular components such that each can advance independent of the other elements. World Wind therefore changed its mission from providing a single information browser to enabling a whole class of 3D geographic applications. Instead of creating a single program, World Wind is a suite of components that can be selectively used in any number of programs. World Wind technology can be a part of any application, or it can be a window in a web page. Or it can be extended with additional functionalities by application and web developers. World Wind makes it possible to include virtual globe visualization and server technology in support of any objective. The world community can continually benefit from advances made in the technology by NASA in concert with the world community. 3. OPEN SOURCE AND OPEN STANDARDS NASA World Wind is NASA Open Source software. This means that the source code is fully accessible for anyone to freely use, even in association with proprietary technology. Imagery and other data provided by the World Wind servers reside in the public domain, including the data server technology itself. This allows others to deliver their own geospatial data and to provide custom solutions based on users specific needs.

Space-division multiplexing in optical fibres

NASA Astrophysics Data System (ADS)

Richardson, D. J.; Fini, J. M.; Nelson, L. E.

2013-05-01

Optical communication technology has been advancing rapidly for several decades, supporting our increasingly information-driven society and economy. Much of this progress has been in finding innovative ways to increase the data-carrying capacity of a single optical fibre. To achieve this, researchers have explored and attempted to optimize multiplexing in time, wavelength, polarization and phase. Commercial systems now utilize all four dimensions to send more information through a single fibre than ever before. The spatial dimension has, however, remained untapped in single fibres, despite it being possible to manufacture fibres supporting hundreds of spatial modes or containing multiple cores, which could be exploited as parallel channels for independent signals.

Imaging and Analytics: The changing face of Medical Imaging

NASA Astrophysics Data System (ADS)

Foo, Thomas

There have been significant technological advances in imaging capability over the past 40 years. Medical imaging capabilities have developed rapidly, along with technology development in computational processing speed and miniaturization. Moving to all-digital, the number of images that are acquired in a routine clinical examination has increased dramatically from under 50 images in the early days of CT and MRI to more than 500-1000 images today. The staggering number of images that are routinely acquired poses significant challenges for clinicians to interpret the data and to correctly identify the clinical problem. Although the time provided to render a clinical finding has not substantially changed, the amount of data available for interpretation has grown exponentially. In addition, the image quality (spatial resolution) and information content (physiologically-dependent image contrast) has also increased significantly with advances in medical imaging technology. On its current trajectory, medical imaging in the traditional sense is unsustainable. To assist in filtering and extracting the most relevant data elements from medical imaging, image analytics will have a much larger role. Automated image segmentation, generation of parametric image maps, and clinical decision support tools will be needed and developed apace to allow the clinician to manage, extract and utilize only the information that will help improve diagnostic accuracy and sensitivity. As medical imaging devices continue to improve in spatial resolution, functional and anatomical information content, image/data analytics will be more ubiquitous and integral to medical imaging capability.

Evolution and enabling capabilities of spatially resolved techniques for the characterization of heterogeneously catalyzed reactions

DOE PAGES

Morgan, Kevin; Touitou, Jamal; Choi, Jae -Soon; ...

2016-01-15

The development and optimization of catalysts and catalytic processes requires knowledge of reaction kinetics and mechanisms. In traditional catalyst kinetic characterization, the gas composition is known at the inlet, and the exit flow is measured to determine changes in concentration. As such, the progression of the chemistry within the catalyst is not known. Technological advances in electromagnetic and physical probes have made visualizing the evolution of the chemistry within catalyst samples a reality, as part of a methodology commonly known as spatial resolution. Herein, we discuss and evaluate the development of spatially resolved techniques, including the evolutions and achievements ofmore » this growing area of catalytic research. The impact of such techniques is discussed in terms of the invasiveness of physical probes on catalytic systems, as well as how experimentally obtained spatial profiles can be used in conjunction with kinetic modeling. Moreover, some aims and aspirations for further evolution of spatially resolved techniques are considered.« less

Characterizing China's energy consumption with selective economic factors and energy-resource endowment: a spatial econometric approach

NASA Astrophysics Data System (ADS)

Jiang, Lei; Ji, Minhe; Bai, Ling

2015-06-01

Coupled with intricate regional interactions, the provincial disparity of energy-resource endowment and other economic conditions in China have created spatially complex energy consumption patterns that require analyses beyond the traditional ones. To distill the spatial effect out of the resource and economic factors on China's energy consumption, this study recast the traditional econometric model in a spatial context. Several analytic steps were taken to reveal different aspects of the issue. Per capita energy consumption (AVEC) at the provincial level was first mapped to reveal spatial clusters of high energy consumption being located in either well developed or energy resourceful regions. This visual spatial autocorrelation pattern of AVEC was quantitatively tested to confirm its existence among Chinese provinces. A Moran scatterplot was employed to further display a relatively centralized trend occurring in those provinces that had parallel AVEC, revealing a spatial structure with attraction among high-high or low-low regions and repellency among high-low or low-high regions. By a comparison between the ordinary least square (OLS) model and its spatial econometric counterparts, a spatial error model (SEM) was selected to analyze the impact of major economic determinants on AVEC. While the analytic results revealed a significant positive correlation between AVEC and economic development, other determinants showed some intricate influential patterns. The provinces endowed with rich energy reserves were inclined to consume much more energy than those otherwise, whereas changing the economic structure by increasing the proportion of secondary and tertiary industries also tended to consume more energy. Both situations seem to underpin the fact that these provinces were largely trapped in the economies that were supported by technologies of low energy efficiency during the period, while other parts of the country were rapidly modernized by adopting advanced technologies and more efficient industries. On the other hand, institutional change (i.e., marketization) and innovation (i.e., technological progress) exerted positive impacts on AVEC improvement, as always expected in this and other studies. Finally, the model comparison indicated that SEM was capable of separating spatial effect from the error term of OLS, so as to improve goodness-of-fit and the significance level of individual determinants.

Recent advances in high-throughput QCL-based infrared microspectral imaging (Conference Presentation)

NASA Astrophysics Data System (ADS)

Rowlette, Jeremy A.; Fotheringham, Edeline; Nichols, David; Weida, Miles J.; Kane, Justin; Priest, Allen; Arnone, David B.; Bird, Benjamin; Chapman, William B.; Caffey, David B.; Larson, Paul; Day, Timothy

2017-02-01

The field of infrared spectral imaging and microscopy is advancing rapidly due in large measure to the recent commercialization of the first high-throughput, high-spatial-definition quantum cascade laser (QCL) microscope. Having speed, resolution and noise performance advantages while also eliminating the need for cryogenic cooling, its introduction has established a clear path to translating the well-established diagnostic capability of infrared spectroscopy into clinical and pre-clinical histology, cytology and hematology workflows. Demand for even higher throughput while maintaining high-spectral fidelity and low-noise performance continues to drive innovation in QCL-based spectral imaging instrumentation. In this talk, we will present for the first time, recent technological advances in tunable QCL photonics which have led to an additional 10X enhancement in spectral image data collection speed while preserving the high spectral fidelity and SNR exhibited by the first generation of QCL microscopes. This new approach continues to leverage the benefits of uncooled microbolometer focal plane array cameras, which we find to be essential for ensuring both reproducibility of data across instruments and achieving the high-reliability needed in clinical applications. We will discuss the physics underlying these technological advancements as well as the new biomedical applications these advancements are enabling, including automated whole-slide infrared chemical imaging on clinically relevant timescales.

Geographic Information Systems and travel health.

PubMed

Bauer, Irmgard L; Puotinen, Marji

2002-01-01

Questions dealing with space and/or location have always been integral to understanding and addressing health issues, such as charting the spread of a disease. Health researchers have traditionally used paper maps to explore the spatial dimensions of health. However, due to advances in technology, it is now possible to ask such questions using a suite of computer-based methods and tools that are collectively known as a Geographic Information System (GIS).

Hyperspectral fluorescence imaging system for biomedical diagnostics

NASA Astrophysics Data System (ADS)

Martin, Matthew E.; Wabuyele, Musundi B.; Panjehpour, Masoud; Phan, Mary N.; Overholt, Bergein F.; Vo-Dinh, Tuan

2006-02-01

An advanced hyper-spectral imaging (HSI) system has been developed for use in medical diagnostics. One such diagnostic, esophageal cancer is diagnosed currently through biopsy and subsequent pathology. The end goal of this research is to develop an optical-based technique to assist or replace biopsy. In this paper, we demonstrate an instrument that has the capability to optically diagnose cancer in laboratory mice. We have developed a real-time HSI system based on state-of-the-art liquid crystal tunable filter (LCTF) technology coupled to an endoscope. This unique HSI technology is being developed to obtain spatially resolved images of the slight differences in luminescent properties of normal versus tumorous tissues. In this report, an in-vivo mouse study is shown. A predictive measure of cancer for the mice studied is developed and shown. It is hoped that the results of this study will lead to advances in the optical diagnosis of esophageal cancer in humans.

Geological mapping goes 3-D in response to societal needs

USGS Publications Warehouse

Thorleifson, H.; Berg, R.C.; Russell, H.A.J.

2010-01-01

The transition to 3-D mapping has been made possible by technological advances in digital cartography, GIS, data storage, analysis, and visualization. Despite various challenges, technological advancements facilitated a gradual transition from 2-D maps to 2.5-D draped maps to 3-D geological mapping, supported by digital spatial and relational databases that can be interrogated horizontally or vertically and viewed interactively. Challenges associated with data collection, human resources, and information management are daunting due to their resource and training requirements. The exchange of strategies at the workshops has highlighted the use of basin analysis to develop a process-based predictive knowledge framework that facilitates data integration. Three-dimensional geological information meets a public demand that fills in the blanks left by conventional 2-D mapping. Two-dimensional mapping will, however, remain the standard method for extensive areas of complex geology, particularly where deformed igneous and metamorphic rocks defy attempts at 3-D depiction.

A smarter way to search, share and utilize open-spatial online data for energy R&D - Custom machine learning and GIS tools in U.S. DOE's virtual data library & laboratory, EDX

NASA Astrophysics Data System (ADS)

Rose, K.; Bauer, J.; Baker, D.; Barkhurst, A.; Bean, A.; DiGiulio, J.; Jones, K.; Jones, T.; Justman, D.; Miller, R., III; Romeo, L.; Sabbatino, M.; Tong, A.

2017-12-01

As spatial datasets are increasingly accessible through open, online systems, the opportunity to use these resources to address a range of Earth system questions grows. Simultaneously, there is a need for better infrastructure and tools to find and utilize these resources. We will present examples of advanced online computing capabilities, hosted in the U.S. DOE's Energy Data eXchange (EDX), that address these needs for earth-energy research and development. In one study the computing team developed a custom, machine learning, big data computing tool designed to parse the web and return priority datasets to appropriate servers to develop an open-source global oil and gas infrastructure database. The results of this spatial smart search approach were validated against expert-driven, manual search results which required a team of seven spatial scientists three months to produce. The custom machine learning tool parsed online, open systems, including zip files, ftp sites and other web-hosted resources, in a matter of days. The resulting resources were integrated into a geodatabase now hosted for open access via EDX. Beyond identifying and accessing authoritative, open spatial data resources, there is also a need for more efficient tools to ingest, perform, and visualize multi-variate, spatial data analyses. Within the EDX framework, there is a growing suite of processing, analytical and visualization capabilities that allow multi-user teams to work more efficiently in private, virtual workspaces. An example of these capabilities are a set of 5 custom spatio-temporal models and data tools that form NETL's Offshore Risk Modeling suite that can be used to quantify oil spill risks and impacts. Coupling the data and advanced functions from EDX with these advanced spatio-temporal models has culminated with an integrated web-based decision-support tool. This platform has capabilities to identify and combine data across scales and disciplines, evaluate potential environmental, social, and economic impacts, highlight knowledge or technology gaps, and reduce uncertainty for a range of `what if' scenarios relevant to oil spill prevention efforts. These examples illustrate EDX's growing capabilities for advanced spatial data search and analysis to support geo-data science needs.

Characterization of single α-tracks by photoresist detection and AFM analysis-focus on biomedical science and technology

NASA Astrophysics Data System (ADS)

Falzone, Nadia; Myhra, Sverre; Chakalova, Radka; Hill, Mark A.; Thomson, James; Vallis, Katherine A.

2013-11-01

The interactions between energetic ions and biological and/or organic target materials have recently attracted theoretical and experimental attention, due to their implications for detector and device technologies, and for therapeutic applications. Most of the attention has focused on detection of the primary ionization tracks, and their effects, while recoil target atom tracks remain largely unexplored. Detection of tracks by a negative tone photoresist (SU-8), followed by standard development, in combination with analysis by atomic force microscopy, shows that both primary and recoil tracks are revealed as conical spikes, and can be characterized at high spatial resolution. The methodology has the potential to provide detailed information about single impact events, which may lead to more effective and informative detector technologies and advanced therapeutic procedures. In comparison with current characterization methods the advantageous features include: greater spatial resolution by an order of magnitude (20 nm) detection of single primary and associated recoil tracks; increased range of fluence (to 2.5 × 109 cm-2) sensitivity to impacts at grazing angle incidence; and better definition of the lateral interaction volume in target materials.

Large-scale, high-definition Ground Penetrating Radar prospection in archaeology

NASA Astrophysics Data System (ADS)

Trinks, I.; Kucera, M.; Hinterleitner, A.; Löcker, K.; Nau, E.; Neubauer, W.; Zitz, T.

2012-04-01

The future demands on professional archaeological prospection will be its ability to cover large areas in a time and cost efficient manner with very high spatial resolution and accuracy. The objective of the 2010 in Vienna established Ludwig Boltzmann Institute for Archaeological Prospection and Virtual Archaeology (LBI ArchPro) in collaboration with its eight European partner organisations is the advancement of state-of-the-art archaeological sciences. The application and specific further development of remote sensing, geophysical prospection and virtual reality applications, as well as of novel integrated interpretation approaches dedicated to non-invasive spatial archaeology combining near-surface prospection methods with advanced computer science is crucial for modern archaeology. Within the institute's research programme different areas for distinct case studies in Austria, Germany, Norway, Sweden and the UK have been selected as basis for the development and testing of new concepts for efficient and universally applicable tools for spatial, non-invasive archaeology. In terms of geophysical prospection the investigation of entire archaeological landscapes for the exploration and protection of Europe's buried cultural heritage requires new measurement devices, which are fast, accurate and precise. Therefore the further development of motorized, multichannel survey systems and advanced navigation solutions is required. The use of motorized measurement devices for archaeological prospection implicates several technological and methodological challenges. Latest multichannel Ground Penetrating Radar (GPR) arrays mounted in front off, or towed behind motorized survey vehicles permit large-scale GPR prospection surveys with unprecedented spatial resolution. In particular the motorized 16 channel 400 MHz MALÅ Imaging Radar Array (MIRA) used by the LBI ArchPro in combination with latest automatic data positioning and navigation solutions permits the reliable high-definition survey of two to three hectares per day with eight centimetres GPR trace spacing, both inline and cross-line. Exact real time positioning of the motorized multichannel arrays with centimetre accuracy is of paramount importance for data quality and subsequent imaging, analysis and interpretation. Whereas traditional surveys are conducted along straight lines fixed on the ground, motorized survey systems require the use of more efficient data positioning and navigation solutions. A promising approach can be realized using real-time kinematic positioning technology based on GPS systems and robotic total-stations with centimetre accuracy. Due to the huge amount and complexity of the data unique software solutions for efficient, appropriate processing and data visualization have been developed permitting the generation of geo-referenced depth-slice images covering up to 70 hectares each. While our focus is on archaeological sites, the presented novel GPR technology and methodology are likewise applicable to Civil Engineering Applications.

Recent advances in rice genome and chromosome structure research by fluorescence in situ hybridization (FISH).

PubMed

Ohmido, Nobuko; Fukui, Kiichi; Kinoshita, Toshiro

2010-01-01

Fluorescence in situ hybridization (FISH) is an effective method for the physical mapping of genes and repetitive DNA sequences on chromosomes. Physical mapping of unique nucleotide sequences on specific rice chromosome regions was performed using a combination of chromosome identification and highly sensitive FISH. Increases in the detection sensitivity of smaller DNA sequences and improvements in spatial resolution have ushered in a new phase in FISH technology. Thus, it is now possible to perform in situ hybridization on somatic chromosomes, pachytene chromosomes, and even on extended DNA fibers (EDFs). Pachytene-FISH allows the integration of genetic linkage maps and quantitative chromosome maps. Visualization methods using FISH can reveal the spatial organization of the centromere, heterochromatin/euchromatin, and the terminal structures of rice chromosomes. Furthermore, EDF-FISH and the DNA combing technique can resolve a spatial distance of 1 kb between adjacent DNA sequences, and the detection of even a 300-bp target is now feasible. The copy numbers of various repetitive sequences and the sizes of various DNA molecules were quantitatively measured using the molecular combing technique. This review describes the significance of these advances in molecular cytology in rice and discusses future applications in plant studies using visualization techniques.

Mobile Air Quality Studies (MAQS)-an international project.

PubMed

Groneberg, David A; Scutaru, Cristian; Lauks, Mathias; Takemura, Masaya; Fischer, Tanja C; Kölzow, Silvana; van Mark, Anke; Uibel, Stefanie; Wagner, Ulrich; Vitzthum, Karin; Beck, Fabian; Mache, Stefanie; Kreiter, Carolin; Kusma, Bianca; Friedebold, Annika; Zell, Hanna; Gerber, Alexander; Bock, Johanna; Al-Mutawakl, Khaled; Donat, Johannes; Geier, Maria Victoria; Pilzner, Carolin; Welker, Pia; Joachim, Ricarda; Bias, Harald; Götting, Michael; Sakr, Mohannad; Addicks, Johann P; Börger, Julia-Annik; Jensen, Anna-Maria; Grajewski, Sonja; Shami, Awfa; Neye, Niko; Kröger, Stefan; Hoffmann, Sarah; Kloss, Lisa; Mayer, Sebastian; Puk, Clemens; Henkel, Ulrich; Rospino, Robert; Schilling, Ute; Krieger, Evelyn; Westphal, Gesa; Meyer-Falcke, Andreas; Hupperts, Hagen; de Roux, Andrés; Tropp, Salome; Weiland, Marco; Mühlbach, Janette; Steinberg, Johannes; Szerwinski, Anne; Falahkohan, Sepiede; Sudik, Claudia; Bircks, Anna; Noga, Oliver; Dickgreber, Nicolas; Dinh, Q Thai; Golpon, Heiko; Kloft, Beatrix; Groneberg, Rafael Neill B; Witt, Christian; Wicker, Sabine; Zhang, Li; Springer, Jochen; Kütting, Birgitta; Mingomataj, Ervin C; Fischer, Axel; Schöffel, Norman; Unger, Volker; Quarcoo, David

2010-04-09

Due to an increasing awareness of the potential hazardousness of air pollutants, new laws, rules and guidelines have recently been implemented globally. In this respect, numerous studies have addressed traffic-related exposure to particulate matter using stationary technology so far. By contrast, only few studies used the advanced technology of mobile exposure analysis. The Mobile Air Quality Study (MAQS) addresses the issue of air pollutant exposure by combining advanced high-granularity spatial-temporal analysis with vehicle-mounted, person-mounted and roadside sensors. The MAQS-platform will be used by international collaborators in order 1) to assess air pollutant exposure in relation to road structure, 2) to assess air pollutant exposure in relation to traffic density, 3) to assess air pollutant exposure in relation to weather conditions, 4) to compare exposure within vehicles between front and back seat (children) positions, and 5) to evaluate "traffic zone"-exposure in relation to non-"traffic zone"-exposure.Primarily, the MAQS-platform will focus on particulate matter. With the establishment of advanced mobile analysis tools, it is planed to extend the analysis to other pollutants including NO2, SO2, nanoparticles and ozone.

Biogenicity and Syngeneity of Organic Matter in Ancient Sedimentary Rocks: Recent Advances in the Search for Evidence of Past Life

NASA Astrophysics Data System (ADS)

Oehler, Dorothy Z.; Cady, Sherry L.

2014-08-01

The past decade has seen an explosion of new technologies for assessment of biogenicity and syngeneity of carbonaceous material within sedimentary rocks. Advances have been made in techniques for analysis of in situ organic matter as well as for extracted bulk samples of soluble and insoluble (kerogen) organic fractions. The in situ techniques allow analysis of micrometer-to-sub-micrometer-scale organic residues within their host rocks and include Raman and fluorescence spectroscopy/imagery, confocal laser scanning microscopy, and forms of secondary ion/laser-based mass spectrometry, analytical transmission electron microscopy, and X-ray absorption microscopy/spectroscopy. Analyses can be made for chemical, molecular, and isotopic composition coupled with assessment of spatial relationships to surrounding minerals, veins, and fractures. The bulk analyses include improved methods for minimizing contamination and recognizing syngenetic constituents of soluble organic fractions as well as enhanced spectroscopic and pyrolytic techniques for unlocking syngenetic molecular signatures in kerogen. Together, these technologies provide vital tools for the study of some of the oldest and problematic carbonaceous residues and for advancing our understanding of the earliest stages of biological evolution on Earth and the search for evidence of life beyond Earth. We discuss each of these new technologies, emphasizing their advantages and disadvantages, applications, and likely future directions.

Geospatial Technology and Geosciences - Defining the skills and competencies in the geosciences needed to effectively use the technology (Invited)

NASA Astrophysics Data System (ADS)

Johnson, A.

2010-12-01

Maps, spatial and temporal data and their use in analysis and visualization are integral components for studies in the geosciences. With the emergence of geospatial technology (Geographic Information Systems (GIS), remote sensing and imagery, Global Positioning Systems (GPS) and mobile technologies) scientists and the geosciences user community are now able to more easily accessed and share data, analyze their data and present their results. Educators are also incorporating geospatial technology into their geosciences programs by including an awareness of the technology in introductory courses to advanced courses exploring the capabilities to help answer complex questions in the geosciences. This paper will look how the new Geospatial Technology Competency Model from the Department of Labor can help ensure that geosciences programs address the skills and competencies identified by the workforce for geospatial technology as well as look at new tools created by the GeoTech Center to help do self and program assessments.

Matrix assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) for direct visualization of plant metabolites in situ

DOE PAGES

Sturtevant, Drew; Lee, Young -Jin; Chapman, Kent D.

2015-11-22

Direct visualization of plant tissues by matrix assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) has revealed key insights into the localization of metabolites in situ. Recent efforts have determined the spatial distribution of primary and secondary metabolites in plant tissues and cells. Strategies have been applied in many areas of metabolism including isotope flux analyses, plant interactions, and transcriptional regulation of metabolite accumulation. Technological advances have pushed achievable spatial resolution to subcellular levels and increased instrument sensitivity by several orders of magnitude. Furthermore, it is anticipated that MALDI-MSI and other MSI approaches will bring a new level of understanding tomore » metabolomics as scientists will be encouraged to consider spatial heterogeneity of metabolites in descriptions of metabolic pathway regulation.« less

Matrix assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) for direct visualization of plant metabolites in situ

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sturtevant, Drew; Lee, Young -Jin; Chapman, Kent D.

Direct visualization of plant tissues by matrix assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) has revealed key insights into the localization of metabolites in situ. Recent efforts have determined the spatial distribution of primary and secondary metabolites in plant tissues and cells. Strategies have been applied in many areas of metabolism including isotope flux analyses, plant interactions, and transcriptional regulation of metabolite accumulation. Technological advances have pushed achievable spatial resolution to subcellular levels and increased instrument sensitivity by several orders of magnitude. Furthermore, it is anticipated that MALDI-MSI and other MSI approaches will bring a new level of understanding tomore » metabolomics as scientists will be encouraged to consider spatial heterogeneity of metabolites in descriptions of metabolic pathway regulation.« less

Photogrammetry and remote sensing for visualization of spatial data in a virtual reality environment

NASA Astrophysics Data System (ADS)

Bhagawati, Dwipen

2001-07-01

Researchers in many disciplines have started using the tool of Virtual Reality (VR) to gain new insights into problems in their respective disciplines. Recent advances in computer graphics, software and hardware technologies have created many opportunities for VR systems, advanced scientific and engineering applications being among them. In Geometronics, generally photogrammetry and remote sensing are used for management of spatial data inventory. VR technology can be suitably used for management of spatial data inventory. This research demonstrates usefulness of VR technology for inventory management by taking the roadside features as a case study. Management of roadside feature inventory involves positioning and visualization of the features. This research has developed a methodology to demonstrate how photogrammetric principles can be used to position the features using the video-logging images and GPS camera positioning and how image analysis can help produce appropriate texture for building the VR, which then can be visualized in a Cave Augmented Virtual Environment (CAVE). VR modeling was implemented in two stages to demonstrate the different approaches for modeling the VR scene. A simulated highway scene was implemented with the brute force approach, while modeling software was used to model the real world scene using feature positions produced in this research. The first approach demonstrates an implementation of the scene by writing C++ codes to include a multi-level wand menu for interaction with the scene that enables the user to interact with the scene. The interactions include editing the features inside the CAVE display, navigating inside the scene, and performing limited geographic analysis. The second approach demonstrates creation of a VR scene for a real roadway environment using feature positions determined in this research. The scene looks realistic with textures from the real site mapped on to the geometry of the scene. Remote sensing and digital image processing techniques were used for texturing the roadway features in this scene.

Technology advancing the study of animal cognition: using virtual reality to present virtually simulated environments to investigate nonhuman primate spatial cognition

PubMed Central

Schweller, Kenneth; Milne, Scott

2017-01-01

Abstract Virtual simulated environments provide multiple ways of testing cognitive function and evaluating problem solving with humans (e.g., Woollett et al. 2009). The use of such interactive technology has increasingly become an essential part of modern life (e.g., autonomously driving vehicles, global positioning systems (GPS), and touchscreen computers; Chinn and Fairlie 2007; Brown 2011). While many nonhuman animals have their own forms of "technology", such as chimpanzees who create and use tools, in captive animal environments the opportunity to actively participate with interactive technology is not often made available. Exceptions can be found in some state-of-the-art zoos and laboratory facilities (e.g., Mallavarapu and Kuhar 2005). When interactive technology is available, captive animals often selectively choose to engage with it. This enhances the animal’s sense of control over their immediate surroundings (e.g., Clay et al. 2011; Ackerman 2012). Such self-efficacy may help to fulfill basic requirements in a species’ daily activities using problem solving that can involve foraging and other goal-oriented behaviors. It also assists in fulfilling the strong underlying motivation for contrafreeloading and exploration expressed behaviorally by many species in captivity (Young 1999). Moreover, being able to present nonhuman primates virtual reality environments under experimental conditions provides the opportunity to gain insight into their navigational abilities and spatial cognition. It allows for insight into the generation and application of internal mental representations of landmarks and environments under multiple conditions (e.g., small- and large-scale space) and subsequent spatial behavior. This paper reviews methods using virtual reality developed to investigate the spatial cognitive abilities of nonhuman primates, and great apes in particular, in comparison with that of humans of multiple age groups. We make recommendations about training, best practices, and also pitfalls to avoid. PMID:29491967

Technology advancing the study of animal cognition: using virtual reality to present virtually simulated environments to investigate nonhuman primate spatial cognition.

PubMed

Dolins, Francine L; Schweller, Kenneth; Milne, Scott

2017-02-01

Virtual simulated environments provide multiple ways of testing cognitive function and evaluating problem solving with humans (e.g., Woollett et al. 2009). The use of such interactive technology has increasingly become an essential part of modern life (e.g., autonomously driving vehicles, global positioning systems (GPS), and touchscreen computers; Chinn and Fairlie 2007; Brown 2011). While many nonhuman animals have their own forms of "technology", such as chimpanzees who create and use tools, in captive animal environments the opportunity to actively participate with interactive technology is not often made available. Exceptions can be found in some state-of-the-art zoos and laboratory facilities (e.g., Mallavarapu and Kuhar 2005). When interactive technology is available, captive animals often selectively choose to engage with it. This enhances the animal's sense of control over their immediate surroundings (e.g., Clay et al. 2011; Ackerman 2012). Such self-efficacy may help to fulfill basic requirements in a species' daily activities using problem solving that can involve foraging and other goal-oriented behaviors. It also assists in fulfilling the strong underlying motivation for contrafreeloading and exploration expressed behaviorally by many species in captivity (Young 1999). Moreover, being able to present nonhuman primates virtual reality environments under experimental conditions provides the opportunity to gain insight into their navigational abilities and spatial cognition. It allows for insight into the generation and application of internal mental representations of landmarks and environments under multiple conditions (e.g., small- and large-scale space) and subsequent spatial behavior. This paper reviews methods using virtual reality developed to investigate the spatial cognitive abilities of nonhuman primates, and great apes in particular, in comparison with that of humans of multiple age groups. We make recommendations about training, best practices, and also pitfalls to avoid.

A Next-Generation Hard X-Ray Nanoprobe Beamline for In Situ Studies of Energy Materials and Devices

NASA Astrophysics Data System (ADS)

Maser, Jörg; Lai, Barry; Buonassisi, Tonio; Cai, Zhonghou; Chen, Si; Finney, Lydia; Gleber, Sophie-Charlotte; Jacobsen, Chris; Preissner, Curt; Roehrig, Chris; Rose, Volker; Shu, Deming; Vine, David; Vogt, Stefan

2014-01-01

The Advanced Photon Source is developing a suite of new X-ray beamlines to study materials and devices across many length scales and under real conditions. One of the flagship beamlines of the APS upgrade is the In Situ Nanoprobe (ISN) beamline, which will provide in situ and operando characterization of advanced energy materials and devices under varying temperatures, gas ambients, and applied fields, at previously unavailable spatial resolution and throughput. Examples of materials systems include inorganic and organic photovoltaic systems, advanced battery systems, fuel cell components, nanoelectronic devices, advanced building materials and other scientifically and technologically relevant systems. To characterize these systems at very high spatial resolution and trace sensitivity, the ISN will use both nanofocusing mirrors and diffractive optics to achieve spots sizes as small as 20 nm. Nanofocusing mirrors in Kirkpatrick-Baez geometry will provide several orders of magnitude increase in photon flux at a spatial resolution of 50 nm. Diffractive optics such as zone plates and/or multilayer Laue lenses will provide a highest spatial resolution of 20 nm. Coherent diffraction methods will be used to study even small specimen features with sub-10 nm relevant length scale. A high-throughput data acquisition system will be employed to significantly increase operations efficiency and usability of the instrument. The ISN will provide full spectroscopy capabilities to study the chemical state of most materials in the periodic table, and enable X-ray fluorescence tomography. In situ electrical characterization will enable operando studies of energy and electronic devices such as photovoltaic systems and batteries. We describe the optical concept for the ISN beamline, the technical design, and the approach for enabling a broad variety of in situ studies. We furthermore discuss the application of hard X-ray microscopy to study defects in multi-crystalline solar cells, one of the lines of inquiries for which the ISN is being developed.

Spacecraft Jitter Attenuation Using Embedded Piezoelectric Actuators

NASA Technical Reports Server (NTRS)

Belvin, W. Keith

1995-01-01

Remote sensing from spacecraft requires precise pointing of measurement devices in order to achieve adequate spatial resolution. Unfortunately, various spacecraft disturbances induce vibrational jitter in the remote sensing instruments. The NASA Langley Research Center has performed analysis, simulations, and ground tests to identify the more promising technologies for minimizing spacecraft pointing jitter. These studies have shown that the use of smart materials to reduce spacecraft jitter is an excellent match between a maturing technology and an operational need. This paper describes the use of embedding piezoelectric actuators for vibration control and payload isolation. In addition, recent advances in modeling, simulation, and testing of spacecraft pointing jitter are discussed.

Community Needs Assessment and Portal Prototype Development for an Arctic Spatial Data Infrastructure (ASDI)

NASA Astrophysics Data System (ADS)

Wiggins, H. V.; Warnick, W. K.; Hempel, L. C.; Henk, J.; Sorensen, M.; Tweedie, C. E.; Gaylord, A. G.

2007-12-01

As the creation and use of geospatial data in research, management, logistics, and education applications has proliferated, there is now a tremendous potential for advancing science through a variety of cyber-infrastructure applications, including Spatial Data Infrastructure (SDI) and related technologies. SDIs provide a necessary and common framework of standards, securities, policies, procedures, and technology to support the effective acquisition, coordination, dissemination and use of geospatial data by multiple and distributed stakeholder and user groups. Despite the numerous research activities in the Arctic, there is no established SDI and, because of this lack of a coordinated infrastructure, there is inefficiency, duplication of effort, and reduced data quality and search ability of arctic geospatial data. The urgency for establishing this framework is significant considering the myriad of data that is being collected in celebration of the International Polar Year (IPY) in 2007-2008 and the current international momentum for an improved and integrated circum-arctic terrestrial-marine-atmospheric environmental observatories network. The key objective of this project is to lay the foundation for full implementation of an Arctic Spatial Data Infrastructure (ASDI) through an assessment of community needs, readiness, and resources and through the development of a prototype web-mapping portal.

An All-reflective Integral Field Spectrograph for Far Ultraviolet Astrophysics

NASA Astrophysics Data System (ADS)

Kendrick, Stephen; Ebbets, D.; Hardesty, C.; Sembach, K.; Beasley, M.; Woodgate, B.

2010-01-01

This paper overviews the supporting optical technologies for an ultraviolet integral field spectrograph (IFS) that will be used for future space astrophysics missions. The new technology is an all-reflective image slicer that directs light to an array of imaging diffraction gratings. Previous UV instruments recorded the spectra of point sources or spatially resolved elements along a long slit. Our IFS has only one reflection more than the Cosmic Origins Spectrograph for Hubble Space Telescope, which is the most sensitive UV spectrograph yet built, but is limited to point sources. An efficient UV IFS enables simultaneous spectroscopy of many spatially resolved elements within a contiguous two dimensional field of view in diagnostically important ultraviolet lines. The output is thus a data cube having one spectral and two spatial coordinates. This is the astrophysical analog to hyperspectral imaging in Earth sciences. The scientific benefits of such an instrument were developed during Vision Missions, Origins Probes, and Astrophysics Strategic Mission Concept Studies between 2004 and 2009. Implementation can be scaled for a small payload such as a sounding rocket or Explorer-class mission, leading to a flight experiment within the next few years. Of particular interest would be the application of this technology for an instrument on a version of the Advanced Technology Large-Aperture Space Telescope (ATLAST) which will have an 8+-m aperture. We will focus on the spectral region near Lyman alpha, but the all-reflective approach is applicable to other spectral regions when matched with wavelength appropriate gratings and detectors. Our project is a collaboration between Ball Aerospace & Technologies Corp., the University of Colorado, NASA Goddard Space Flight Center and the Space Telescope Science Institute, all of which have extensive experience with the science and instrumentation for UV astrophysics.

Quarks and the cosmos.

PubMed

Turner, Michael S

2007-01-05

Cosmology is in the midst of a period of revolutionary discovery, propelled by bold ideas from particle physics and by technological advances from gigapixel charge-coupled device cameras to peta-scale computing. The basic features of the universe have now been determined: It is 13.7 billion years old, spatially flat, and expanding at an accelerating rate; it is composed of atoms (4%), exotic dark matter (20%), and dark energy (76%); and there is evidence that galaxies and other structures were seeded by quantum fluctuations. Although we know much about the universe, we understand far less. Poised to dramatically advance our understanding of both the universe and the laws that govern it, cosmology is on the verge of a golden age.

Acquisition and processing of advanced sensor data for ERW and UXO detection and classification

NASA Astrophysics Data System (ADS)

Schultz, Gregory M.; Keranen, Joe; Miller, Jonathan S.; Shubitidze, Fridon

2014-06-01

The remediation of explosive remnants of war (ERW) and associated unexploded ordnance (UXO) has seen improvements through the injection of modern technological advances and streamlined standard operating procedures. However, reliable and cost-effective detection and geophysical mapping of sites contaminated with UXO such as cluster munitions, abandoned ordnance, and improvised explosive devices rely on the ability to discriminate hazardous items from metallic clutter. In addition to anthropogenic clutter, handheld and vehicle-based metal detector systems are plagued by natural geologic and environmental noise in many post conflict areas. We present new and advanced electromagnetic induction (EMI) technologies including man-portable and towed EMI arrays and associated data processing software. While these systems feature vastly different form factors and transmit-receive configurations, they all exhibit several fundamental traits that enable successful classification of EMI anomalies. Specifically, multidirectional sampling of scattered magnetic fields from targets and corresponding high volume of unique data provide rich information for extracting useful classification features for clutter rejection analysis. The quality of classification features depends largely on the extent to which the data resolve unique physics-based parameters. To date, most of the advanced sensors enable high quality inversion by producing data that are extremely rich in spatial content through multi-angle illumination and multi-point reception.

PACS storage technology update: holographic storage.

PubMed

Colang, John E; Johnston, James N

2006-01-01

This paper focuses on the emerging technology of holographic storage and its effect on picture archiving and communication systems (PACS). A review of the emerging technology is presented, which includes a high level description of holographic drives and the associated substrate media, the laser and optical technology, and the spatial light modulator. The potential advantages and disadvantages of holographic drive and storage technology are evaluated. PACS administrators face myriad complex and expensive storage solutions and selecting an appropriate system is time-consuming and costly. Storage technology may become obsolete quickly because of the exponential nature of the advances in digital storage media. Holographic storage may turn out to be a low cost, high speed, high volume storage solution of the future; however, data is inconclusive at this early stage of the technology lifecycle. Despite the current lack of quantitative data to support the hypothesis that holographic technology will have a significant effect on PACS and standards of practice, it seems likely from the current information that holographic technology will generate significant efficiencies. This paper assumes the reader has a fundamental understanding of PACS technology.

Solid surface vs. liquid surface: nanoarchitectonics, molecular machines, and DNA origami.

PubMed

Ariga, Katsuhiko; Mori, Taizo; Nakanishi, Waka; Hill, Jonathan P

2017-09-13

The investigation of molecules and materials at interfaces is critical for the accumulation of new scientific insights and technological advances in the chemical and physical sciences. Immobilization on solid surfaces permits the investigation of different properties of functional molecules or materials with high sensitivity and high spatial resolution. Liquid surfaces also present important media for physicochemical innovation and insight based on their great flexibility and dynamicity, rapid diffusion of molecular components for mixing and rearrangements, as well as drastic spatial variation in the prevailing dielectric environment. Therefore, a comparative discussion of the relative merits of the properties of materials when positioned at solid or liquid surfaces would be informative regarding present-to-future developments of surface-based technologies. In this perspective article, recent research examples of nanoarchitectonics, molecular machines, DNA nanotechnology, and DNA origami are compared with respect to the type of surface used, i.e. solid surfaces vs. liquid surfaces, for future perspectives of interfacial physics and chemistry.

Review of integrated digital systems: evolution and adoption

NASA Astrophysics Data System (ADS)

Fritz, Lawrence W.

The factors that are influencing the evolution of photogrammetric and remote sensing technology to transition into fully integrated digital systems are reviewed. These factors include societal pressures for new, more timely digital products from the Spatial Information Sciencesand the adoption of rapid technological advancements in digital processing hardware and software. Current major developments in leading government mapping agencies of the USA, such as the Digital Production System (DPS) modernization programme at the Defense Mapping Agency, and the Automated Nautical Charting System II (ANCS-II) programme and Integrated Digital Photogrammetric Facility (IDPF) at NOAA/National Ocean Service, illustrate the significant benefits to be realized. These programmes are examples of different levels of integrated systems that have been designed to produce digital products. They provide insights to the management complexities to be considered for very large integrated digital systems. In recognition of computer industry trends, a knowledge-based architecture for managing the complexity of the very large spatial information systems of the future is proposed.

Potential Natural Vegetation of the Mississippi Alluvial Valley: Boeuf-Tensas Basin, Arkansas, Field Atlas

DTIC Science & Technology

2012-09-01

under the auspices of federal and state research programs or in conjunction with Corps of Engineers project planning efforts. In the process , a...in the field effort and assembled and processed the original project GIS data. Malcolm Williamson (Center for Advanced Spatial Technologies...further improve drainage. ERDC/EL TR-12-28 5 3 Using the PNV map as a model for restoration The PNV mapping process was conceived as a way to

Ultrasound-guided drug delivery in cancer

PubMed Central

2017-01-01

Recent advancements in ultrasound and microbubble (USMB) mediated drug delivery technology has shown that this approach can improve spatially confined delivery of drugs and genes to target tissues while reducing systemic dose and toxicity. The mechanism behind enhanced delivery of therapeutics is sonoporation, the formation of openings in the vasculature, induced by ultrasound-triggered oscillations and destruction of microbubbles. In this review, progress and challenges of USMB mediated drug delivery are summarized, with special focus on cancer therapy. PMID:28607323

Innovative testing of spatial ability: interactive responding and the use of complex stimuli material.

PubMed

Jelínek, Martin; Květon, Petr; Vobořil, Dalibor

2015-02-01

Despite initial expectations, which have emerged with the advancement of computer technology over the last decade of the twentieth century, scientific literature does not contain many relevant references regarding the development and use of innovative items in psychological testing. Our study presents and evaluates two novel item types. One item type is derived from a standard schematic test item used for the assessment of the spatial perception aspect of spatial ability, enhanced by an interactive response module. The performance on this item type is correlated with the performance on its paper and pencil counterpart. The other innovative item type used complex stimuli in the form of a short video of a ride through a city presented in an on-route perspective, which is intended to measure navigation skills and the ability to keep oneself oriented in space. In this case, the scores were related to the capacity of visuo-spatial working memory and also to the overall score in the paper/pencil test of spatial ability. The second relationship was moderated by gender.

Collaborating and sharing data in epilepsy research.

PubMed

Wagenaar, Joost B; Worrell, Gregory A; Ives, Zachary; Dümpelmann, Matthias; Matthias, Dümpelmann; Litt, Brian; Schulze-Bonhage, Andreas

2015-06-01

Technological advances are dramatically advancing translational research in Epilepsy. Neurophysiology, imaging, and metadata are now recorded digitally in most centers, enabling quantitative analysis. Basic and translational research opportunities to use these data are exploding, but academic and funding cultures prevent this potential from being realized. Research on epileptogenic networks, antiepileptic devices, and biomarkers could progress rapidly if collaborative efforts to digest this "big neuro data" could be organized. Higher temporal and spatial resolution data are driving the need for novel multidimensional visualization and analysis tools. Crowd-sourced science, the same that drives innovation in computer science, could easily be mobilized for these tasks, were it not for competition for funding, attribution, and lack of standard data formats and platforms. As these efforts mature, there is a great opportunity to advance Epilepsy research through data sharing and increase collaboration between the international research community.

Tower-Based Greenhouse Gas Measurement Network Design---The National Institute of Standards and Technology North East Corridor Testbed.

PubMed

Lopez-Coto, Israel; Ghosh, Subhomoy; Prasad, Kuldeep; Whetstone, James

2017-09-01

The North-East Corridor (NEC) Testbed project is the 3rd of three NIST (National Institute of Standards and Technology) greenhouse gas emissions testbeds designed to advance greenhouse gas measurements capabilities. A design approach for a dense observing network combined with atmospheric inversion methodologies is described. The Advanced Research Weather Research and Forecasting Model with the Stochastic Time-Inverted Lagrangian Transport model were used to derive the sensitivity of hypothetical observations to surface greenhouse gas emissions (footprints). Unlike other network design algorithms, an iterative selection algorithm, based on a k -means clustering method, was applied to minimize the similarities between the temporal response of each site and maximize sensitivity to the urban emissions contribution. Once a network was selected, a synthetic inversion Bayesian Kalman filter was used to evaluate observing system performance. We present the performances of various measurement network configurations consisting of differing numbers of towers and tower locations. Results show that an overly spatially compact network has decreased spatial coverage, as the spatial information added per site is then suboptimal as to cover the largest possible area, whilst networks dispersed too broadly lose capabilities of constraining flux uncertainties. In addition, we explore the possibility of using a very high density network of lower cost and performance sensors characterized by larger uncertainties and temporal drift. Analysis convergence is faster with a large number of observing locations, reducing the response time of the filter. Larger uncertainties in the observations implies lower values of uncertainty reduction. On the other hand, the drift is a bias in nature, which is added to the observations and, therefore, biasing the retrieved fluxes.

Tower-based greenhouse gas measurement network design—The National Institute of Standards and Technology North East Corridor Testbed

NASA Astrophysics Data System (ADS)

Lopez-Coto, Israel; Ghosh, Subhomoy; Prasad, Kuldeep; Whetstone, James

2017-09-01

The North-East Corridor (NEC) Testbed project is the 3rd of three NIST (National Institute of Standards and Technology) greenhouse gas emissions testbeds designed to advance greenhouse gas measurements capabilities. A design approach for a dense observing network combined with atmospheric inversion methodologies is described. The Advanced Research Weather Research and Forecasting Model with the Stochastic Time-Inverted Lagrangian Transport model were used to derive the sensitivity of hypothetical observations to surface greenhouse gas emissions (footprints). Unlike other network design algorithms, an iterative selection algorithm, based on a k-means clustering method, was applied to minimize the similarities between the temporal response of each site and maximize sensitivity to the urban emissions contribution. Once a network was selected, a synthetic inversion Bayesian Kalman filter was used to evaluate observing system performance. We present the performances of various measurement network configurations consisting of differing numbers of towers and tower locations. Results show that an overly spatially compact network has decreased spatial coverage, as the spatial information added per site is then suboptimal as to cover the largest possible area, whilst networks dispersed too broadly lose capabilities of constraining flux uncertainties. In addition, we explore the possibility of using a very high density network of lower cost and performance sensors characterized by larger uncertainties and temporal drift. Analysis convergence is faster with a large number of observing locations, reducing the response time of the filter. Larger uncertainties in the observations implies lower values of uncertainty reduction. On the other hand, the drift is a bias in nature, which is added to the observations and, therefore, biasing the retrieved fluxes.

Technology Needs for Gamma Ray Astronomy

NASA Technical Reports Server (NTRS)

Gehrels, Neil

2011-01-01

Gamma ray astronomy is currently in an exciting period of multiple missions and a wealth of data. Results from INTEGRAL, Fermi, AGILE, Suzaku and Swift are making large contributions to our knowledge of high energy processes in the universe. The advances are due to new detector and imaging technologies. The steps to date have been from scintillators to solid state detectors for sensors and from light buckets to coded aperture masks and pair telescopes for imagers. A key direction for the future is toward focusing telescopes pushing into the hard X-ray regime and Compton telescopes and pair telescopes with fine spatial resolution for medium and high energy gamma rays. These technologies will provide finer imaging of gamma-ray sources. Importantly, they will also enable large steps forward in sensitivity by reducing background.

Physics of cardiac imaging with multiple-row detector CT.

PubMed

Mahesh, Mahadevappa; Cody, Dianna D

2007-01-01

Cardiac imaging with multiple-row detector computed tomography (CT) has become possible due to rapid advances in CT technologies. Images with high temporal and spatial resolution can be obtained with multiple-row detector CT scanners; however, the radiation dose associated with cardiac imaging is high. Understanding the physics of cardiac imaging with multiple-row detector CT scanners allows optimization of cardiac CT protocols in terms of image quality and radiation dose. Knowledge of the trade-offs between various scan parameters that affect image quality--such as temporal resolution, spatial resolution, and pitch--is the key to optimized cardiac CT protocols, which can minimize the radiation risks associated with these studies. Factors affecting temporal resolution include gantry rotation time, acquisition mode, and reconstruction method; factors affecting spatial resolution include detector size and reconstruction interval. Cardiac CT has the potential to become a reliable tool for noninvasive diagnosis and prevention of cardiac and coronary artery disease. (c) RSNA, 2007.

Optical Probes for Neurobiological Sensing and Imaging.

PubMed

Kim, Eric H; Chin, Gregory; Rong, Guoxin; Poskanzer, Kira E; Clark, Heather A

2018-05-15

Fluorescent nanosensors and molecular probes are next-generation tools for imaging chemical signaling inside and between cells. Electrophysiology has long been considered the gold standard in elucidating neural dynamics with high temporal resolution and precision, particularly on the single-cell level. However, electrode-based techniques face challenges in illuminating the specific chemicals involved in neural cell activation with adequate spatial information. Measuring chemical dynamics is of fundamental importance to better understand synergistic interactions between neurons as well as interactions between neurons and non-neuronal cells. Over the past decade, significant technological advances in optical probes and imaging methods have enabled entirely new possibilities for studying neural cells and circuits at the chemical level. These optical imaging modalities have shown promise for combining chemical, temporal, and spatial information. This potential makes them ideal candidates to unravel the complex neural interactions at multiple scales in the brain, which could be complemented by traditional electrophysiological methods to obtain a full spatiotemporal picture of neurochemical dynamics. Despite the potential, only a handful of probe candidates have been utilized to provide detailed chemical information in the brain. To date, most live imaging and chemical mapping studies rely on fluorescent molecular indicators to report intracellular calcium (Ca 2+ ) dynamics, which correlates with neuronal activity. Methodological advances for monitoring a full array of chemicals in the brain with improved spatial, temporal, and chemical resolution will thus enable mapping of neurochemical circuits with finer precision. On the basis of numerous studies in this exciting field, we review the current efforts to develop and apply a palette of optical probes and nanosensors for chemical sensing in the brain. There is a strong impetus to further develop technologies capable of probing entire neurobiological units with high spatiotemporal resolution. Thus, we introduce selected applications for ion and neurotransmitter detection to investigate both neurons and non-neuronal brain cells. We focus on families of optical probes because of their ability to sense a wide array of molecules and convey spatial information with minimal damage to tissue. We start with a discussion of currently available molecular probes, highlight recent advances in genetically modified fluorescent probes for ions and small molecules, and end with the latest research in nanosensors for biological imaging. Customizable, nanoscale optical sensors that accurately and dynamically monitor the local environment with high spatiotemporal resolution could lead to not only new insights into the function of all cell types but also a broader understanding of how diverse neural signaling systems act in conjunction with neighboring cells in a spatially relevant manner.

Development of a Heterogenic Distributed Environment for Spatial Data Processing Using Cloud Technologies

NASA Astrophysics Data System (ADS)

Garov, A. S.; Karachevtseva, I. P.; Matveev, E. V.; Zubarev, A. E.; Florinsky, I. V.

2016-06-01

We are developing a unified distributed communication environment for processing of spatial data which integrates web-, desktop- and mobile platforms and combines volunteer computing model and public cloud possibilities. The main idea is to create a flexible working environment for research groups, which may be scaled according to required data volume and computing power, while keeping infrastructure costs at minimum. It is based upon the "single window" principle, which combines data access via geoportal functionality, processing possibilities and communication between researchers. Using an innovative software environment the recently developed planetary information system (http://cartsrv.mexlab.ru/geoportal) will be updated. The new system will provide spatial data processing, analysis and 3D-visualization and will be tested based on freely available Earth remote sensing data as well as Solar system planetary images from various missions. Based on this approach it will be possible to organize the research and representation of results on a new technology level, which provides more possibilities for immediate and direct reuse of research materials, including data, algorithms, methodology, and components. The new software environment is targeted at remote scientific teams, and will provide access to existing spatial distributed information for which we suggest implementation of a user interface as an advanced front-end, e.g., for virtual globe system.

Solar and Space Physics Science Enabled by Pico and Nano Satellites

NASA Astrophysics Data System (ADS)

Swenson, C.; Fish, C. S.

2012-12-01

The most significant advances in solar and space physics, or Heliophysics, over the next decade are most likely to derive from new observational techniques. The connection between advances in scientific understanding and technology has historically been demonstrated across many disciplines and time. Progress on some of the most compelling scientific problems will most likely occur through multipoint observations within the space environment to understand the coupling between disparate regions: Heliosphere, magnetosphere, ionosphere, thermosphere and mesosphere. Multipoint measurements are also needed to develop understanding of the various scalars or vector field signatures (i.e gradients, divergence) that arise from coupling processes that occur across temporal and spatial scales or within localized regions. The resources that are available over the next decades for all areas of Heliophysics research have limits and it is therefore important that the community be innovative in developing new observational techniques to advance science. One of the most promising new observational techniques becoming available are miniaturized sensors and satellite systems called pico- or nano-satellites and CubeSats. These are enabled by the enormous investment of the commercial, medical, and defense industries in producing highly capable, portable and low-power battery-operated consumer electronics, in-situ composition probes, and novel reconnaissance sensors. The advancements represented by these technologies have direct application in developing pico- or nano-satellites and CubeSats system for Heliophysics research. In this talk we overview the current environment and technologies surrounding these novel small satellites and discuss the types and capabilities of the miniature sensors that are being developed. We discuss how pico- or nano-satellites and CubeSats can be used to address highest priority science identified in the Decadal Survey and the innovations and advancements that are required to make substantial progress.

In vivo cardiac nano-imaging: A new technology for high-precision analyses of sarcomere dynamics in the heart.

PubMed

Shimozawa, Togo; Hirokawa, Erisa; Kobirumaki-Shimozawa, Fuyu; Oyama, Kotaro; Shintani, Seine A; Terui, Takako; Kushida, Yasuharu; Tsukamoto, Seiichi; Fujii, Teruyuki; Ishiwata, Shin'ichi; Fukuda, Norio

2017-03-01

The cardiac pump function is a result of a rise in intracellular Ca 2+ and the ensuing sarcomeric contractions [i.e., excitation-contraction (EC) coupling] in myocytes in various locations of the heart. In order to elucidate the heart's mechanical properties under various settings, cardiac imaging is widely performed in today's clinical as well as experimental cardiology by using echocardiogram, magnetic resonance imaging and computed tomography. However, because these common techniques detect local myocardial movements at a spatial resolution of ∼100 μm, our knowledge on the sub-cellular mechanisms of the physiology and pathophysiology of the heart in vivo is limited. This is because (1) EC coupling occurs in the μm partition in a myocyte and (2) cardiac sarcomeres generate active force upon a length change of ∼100 nm on a beat-to-beat basis. Recent advances in optical technologies have enabled measurements of intracellular Ca 2+ dynamics and sarcomere length displacements at high spatial and temporal resolution in the beating heart of living rodents. Future studies with these technologies are warranted to open a new era in cardiac research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery.

PubMed

Xing, Jin-Feng; Zheng, Mei-Ling; Duan, Xuan-Ming

2015-08-07

3D printing technology has attracted much attention due to its high potential in scientific and industrial applications. As an outstanding 3D printing technology, two-photon polymerization (TPP) microfabrication has been applied in the fields of micro/nanophotonics, micro-electromechanical systems, microfluidics, biomedical implants and microdevices. In particular, TPP microfabrication is very useful in tissue engineering and drug delivery due to its powerful fabrication capability for precise microstructures with high spatial resolution on both the microscopic and the nanometric scale. The design and fabrication of 3D hydrogels widely used in tissue engineering and drug delivery has been an important research area of TPP microfabrication. The resolution is a key parameter for 3D hydrogels to simulate the native 3D environment in which the cells reside and the drug is controlled to release with optimal temporal and spatial distribution in vitro and in vivo. The resolution of 3D hydrogels largely depends on the efficiency of TPP initiators. In this paper, we will review the widely used photoresists, the development of TPP photoinitiators, the strategies for improving the resolution and the microfabrication of 3D hydrogels.

Biogenicity and Syngeneity of Organic Matter in Ancient Sedimentary Rocks: Recent Advances in the Search for Evidence of Past Life

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oehler, Dorothy Z.; Cady, Sherry L.

2014-12-01

he past decade has seen an explosion of new technologies for assessment of biogenicity and syngeneity of carbonaceous material within sedimentary rocks. Advances have been made in techniques for analysis of in situ organic matter as well as for extracted bulk samples of soluble and insoluble (kerogen) organic fractions. The in situ techniques allow analysis of micrometer-to-sub-micrometer-scale organic residues within their host rocks and include Raman and fluorescence spectroscopy/imagery, confocal laser scanning microscopy, and forms of secondary ion/laser-based mass spectrometry, analytical transmission electron microscopy, and X-ray absorption microscopy/spectroscopy. Analyses can be made for chemical, molecular, and isotopic composition coupled withmore » assessment of spatial relationships to surrounding minerals, veins, and fractures. The bulk analyses include improved methods for minimizing contamination and recognizing syngenetic constituents of soluble organic fractions as well as enhanced spectroscopic and pyrolytic techniques for unlocking syngenetic molecular signatures in kerogen. Together, these technologies provide vital tools for the study of some of the oldest and problematic carbonaceous residues and for advancing our understanding of the earliest stages of biological evolution on Earth and the search for evidence of life beyond Earth. We discuss each of these new technologies, emphasizing their advantages and disadvantages, applications, and likely future directions.« less

3D printing of bacteria into functional complex materials.

PubMed

Schaffner, Manuel; Rühs, Patrick A; Coulter, Fergal; Kilcher, Samuel; Studart, André R

2017-12-01

Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of "living materials" capable of degrading pollutants and of producing medically relevant bacterial cellulose. With this versatile bacteria-printing platform, complex materials displaying spatially specific compositions, geometry, and properties not accessed by standard technologies can be assembled from bottom up for new biotechnological and biomedical applications.

3D printing of bacteria into functional complex materials

PubMed Central

Schaffner, Manuel; Rühs, Patrick A.; Coulter, Fergal; Kilcher, Samuel; Studart, André R.

2017-01-01

Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of “living materials” capable of degrading pollutants and of producing medically relevant bacterial cellulose. With this versatile bacteria-printing platform, complex materials displaying spatially specific compositions, geometry, and properties not accessed by standard technologies can be assembled from bottom up for new biotechnological and biomedical applications. PMID:29214219

Optical system design, analysis, and production for advanced technology systems; Proceedings of the Meeting, Innsbruck, Austria, Apr. 15-17, 1986

NASA Technical Reports Server (NTRS)

Fischer, Robert E. (Editor); Rogers, Philip J. (Editor)

1986-01-01

The present conference considers topics in the fields of optical systems design software, the design and analysis of optical systems, illustrative cases of advanced optical system design, the integration of optical designs into greater systems, and optical fabrication and testing techniques. Attention is given to an extended range diffraction-based merit function for lens design optimization, an assessment of technologies for stray light control and evaluation, the automated characterization of IR systems' spatial resolution, a spectrum of design techniques based on aberration theory, a three-field IR telescope, a large aperture zoom lens for 16-mm motion picture cameras, and the use of concave holographic gratings as monochomators. Also discussed are the use of aspherics in optical systems, glass choice procedures for periscope design, the fabrication and testing of unconventional optics, low mass mirrors for large optics, and the diamond grinding of optical surfaces on aspheric lens molds.

The NPOESS Crosstrack Infrared Sounder (CrIS) and Advanced Technology Microwave Sounder (ATMS) as a Companion to the New Generation AIRS/AMSU and IASI/AMSU Sounder Suites

NASA Astrophysics Data System (ADS)

Bingham, G. E.; Pougatchev, N. S.; Zavyalov, V.; Esplin, M.; Blackwell, W. J.; Barnet, C.

2009-12-01

The NPOESS Preparatory Project is serving the operations and research community as the bridge mission between the Earth Observing System and the National Polar-orbiting Operational Environmental Satellite System. The Cross-track Infrared Sounder (CrIS), combined with the Advanced Technology Microwave Sounder (ATMS) are the core instruments to provide the key performance temperature and humidity profiles (along with some other atmospheric constituent information). Both the high spectral resolution CrIS and the upgraded microwave sounder (ATMS) will be working in parallel with already orbiting Advanced Atmospheric Infrared Sounder (AIRS/AMSU) on EOS AQUA platform and Infrared Atmospheric Sounding Interferometer (IASI/AMSU) on METOP-A satellite. This presentation will review the CrIS/ATMS capabilities in the context of continuity with the excellent performance records established by AIRS and IASI. The CrIS sensor is in the process of its final calibration and characterization testing and the results and Sensor Data Record process are being validated against this excellent dataset. The comparison between CrIS, AIRS, and IASI will include spectral, spatial, radiometric performance and sounding capability comparisons.

Report of the x ray and gamma ray sensors panel

NASA Technical Reports Server (NTRS)

Szymkowiak, Andrew; Collins, S.; Kurfess, J.; Mahoney, W.; Mccammon, D.; Pehl, R.; Ricker, G.

1991-01-01

Overall five major areas of technology are recommended for development in order to meet the science requirements of the Astrotech 21 mission set. These are: detectors for high resolution gamma ray spectroscopy, cryogenic detectors for improved x ray spectral and spatial resolution, advanced x ray charge coupled devices (CCDs) for higher energy resolution and larger format, extension to higher energies, liquid and solid position sensitive detectors for improving stopping power in the energy range 5 to 500 keV and 0.2 to 2 MeV. Development plans designed to achieve the desired capabilities on the time scales required by the technology freeze dates have been recommended in each of these areas.

In situ, operando measurements of rechargeable batteries

DOE PAGES

Wang, Howard; Wang, Feng

2016-08-01

This article reviews recent in operando measurements (IOMs) for addressing challenges in advancing rechargeable battery (RB) technologies. As the demands on energy and power density of RBs for broader applications continue to grow, current RB technologies are pushed to their theoretical and engineering limits while new approaches are being extensively investigated. Also, IOMs have become more powerful and effective research tools in recent years; they will play an essential role in developing next generation RBs. This review is organized around outstanding issues in battery science and engineering. Finally, we emphasize the critical need for quantifying the distribution and transport ofmore » active ions in functioning batteries over wide temporal and spatial scales in real time.« less

Optical computing, optical memory, and SBIRs at Foster-Miller

NASA Astrophysics Data System (ADS)

Domash, Lawrence H.

1994-03-01

A desktop design and manufacturing system for binary diffractive elements, MacBEEP, was developed with the optical researcher in mind. Optical processing systems for specialized tasks such as cellular automation computation and fractal measurement were constructed. A new family of switchable holograms has enabled several applications for control of laser beams in optical memories. New spatial light modulators and optical logic elements have been demonstrated based on a more manufacturable semiconductor technology. Novel synthetic and polymeric nonlinear materials for optical storage are under development in an integrated memory architecture. SBIR programs enable creative contributions from smaller companies, both product oriented and technology oriented, and support advances that might not otherwise be developed.

Implications of sensor design for coral reef detection: Upscaling ground hyperspectral imagery in spatial and spectral scales

NASA Astrophysics Data System (ADS)

Caras, Tamir; Hedley, John; Karnieli, Arnon

2017-12-01

Remote sensing offers a potential tool for large scale environmental surveying and monitoring. However, remote observations of coral reefs are difficult especially due to the spatial and spectral complexity of the target compared to sensor specifications as well as the environmental implications of the water medium above. The development of sensors is driven by technological advances and the desired products. Currently, spaceborne systems are technologically limited to a choice between high spectral resolution and high spatial resolution, but not both. The current study explores the dilemma of whether future sensor design for marine monitoring should prioritise on improving their spatial or spectral resolution. To address this question, a spatially and spectrally resampled ground-level hyperspectral image was used to test two classification elements: (1) how the tradeoff between spatial and spectral resolutions affects classification; and (2) how a noise reduction by majority filter might improve classification accuracy. The studied reef, in the Gulf of Aqaba (Eilat), Israel, is heterogeneous and complex so the local substrate patches are generally finer than currently available imagery. Therefore, the tested spatial resolution was broadly divided into four scale categories from five millimeters to one meter. Spectral resolution resampling aimed to mimic currently available and forthcoming spaceborne sensors such as (1) Environmental Mapping and Analysis Program (EnMAP) that is characterized by 25 bands of 6.5 nm width; (2) VENμS with 12 narrow bands; and (3) the WorldView series with broadband multispectral resolution. Results suggest that spatial resolution should generally be prioritized for coral reef classification because the finer spatial scale tested (pixel size < 0.1 m) may compensate for some low spectral resolution drawbacks. In this regard, it is shown that the post-classification majority filtering substantially improves the accuracy of all pixel sizes up to the point where the kernel size reaches the average unit size (pixel < 0.25 m). However, careful investigation as to the effect of band distribution and choice could improve the sensor suitability for the marine environment task. This in mind, while the focus in this study was on the technologically limited spaceborne design, aerial sensors may presently provide an opportunity to implement the suggested setup.

Advances in nonmarket valuation econometrics: Spatial heterogeneity in hedonic pricing models and preference heterogeneity in stated preference models

NASA Astrophysics Data System (ADS)

Yoo, Jin Woo

In my 1st essay, the study explores Pennsylvania residents. willingness to pay for development of renewable energy technologies such as solar power, wind power, biomass electricity, and other renewable energy using a choice experiment method. Principle component analysis identified 3 independent attitude components that affect the variation of preference, a desire for renewable energy and environmental quality and concern over cost. The results show that urban residents have a higher desire for environmental quality and concern less about cost than rural residents and consequently have a higher willingness to pay to increase renewable energy production. The results of sub-sample analysis show that a representative respondent in rural (urban) Pennsylvania is willing to pay 3.8(5.9) and 4.1(5.7)/month for increasing the share of Pennsylvania electricity generated from wind power and other renewable energy by 1 percent point, respectively. Mean WTP for solar and biomass electricity was not significantly different from zero. In my second essay, heterogeneity of individual WTP for various renewable energy technologies is investigated using several different variants of the multinomial logit model: a simple MNL with interaction terms, a latent class choice model, a random parameter mixed logit choice model, and a random parameter-latent class choice model. The results of all models consistently show that respondents. preference for individual renewable technology is heterogeneous, but the degree of heterogeneity differs for different renewable technologies. In general, the random parameter logit model with interactions and a hybrid random parameter logit-latent class model fit better than other models and better capture respondents. heterogeneity of preference for renewable energy. The impact of the land under agricultural conservation easement (ACE) contract on the values of nearby residential properties is investigated using housing sales data in two Pennsylvania Counties. The spatial-lag (SLM), the spatial error (SEM) and the spatial error component (SEC) models were compared. A geographically weighted regression (GWR) model is estimated to study the spatial heterogeneity of the marginal implicit prices of ACE impact within each county. New hybrid spatial hedonic models, the GWR-SEC and a modified GWR-SEM, are estimated such that both spatial autocorrelation and heterogeneity are accounted. The results show that the coefficient of land under easement contract varies spatially within one county, but not within the other county studied. Also, ACE's are found to have both positive and negative impacts on the values of nearby residential properties. Among global spatial models, the SEM fit better than the SLM and the SEC. Statistical goodness of fit measures showed that the GWR-SEC model fit better than the GWR or the GWR-SEC model. Finally, the GWR-SEC showed spatial autocorrelation is stronger in one county than in the other county.

Integration of environmental simulation models with satellite remote sensing and geographic information systems technologies: case studies

USGS Publications Warehouse

Steyaert, Louis T.; Loveland, Thomas R.; Brown, Jesslyn F.; Reed, Bradley C.

1993-01-01

Environmental modelers are testing and evaluating a prototype land cover characteristics database for the conterminous United States developed by the EROS Data Center of the U.S. Geological Survey and the University of Nebraska Center for Advanced Land Management Information Technologies. This database was developed from multi temporal, 1-kilometer advanced very high resolution radiometer (AVHRR) data for 1990 and various ancillary data sets such as elevation, ecological regions, and selected climatic normals. Several case studies using this database were analyzed to illustrate the integration of satellite remote sensing and geographic information systems technologies with land-atmosphere interactions models at a variety of spatial and temporal scales. The case studies are representative of contemporary environmental simulation modeling at local to regional levels in global change research, land and water resource management, and environmental simulation modeling at local to regional levels in global change research, land and water resource management and environmental risk assessment. The case studies feature land surface parameterizations for atmospheric mesoscale and global climate models; biogenic-hydrocarbons emissions models; distributed parameter watershed and other hydrological models; and various ecological models such as ecosystem, dynamics, biogeochemical cycles, ecotone variability, and equilibrium vegetation models. The case studies demonstrate the important of multi temporal AVHRR data to develop to develop and maintain a flexible, near-realtime land cover characteristics database. Moreover, such a flexible database is needed to derive various vegetation classification schemes, to aggregate data for nested models, to develop remote sensing algorithms, and to provide data on dynamic landscape characteristics. The case studies illustrate how such a database supports research on spatial heterogeneity, land use, sensitivity analysis, and scaling issues involving regional extrapolations and parameterizations of dynamic land processes within simulation models.

Emerging Technologies for Assessing Physical Activity Behaviors in Space and Time

PubMed Central

Hurvitz, Philip M.; Moudon, Anne Vernez; Kang, Bumjoon; Saelens, Brian E.; Duncan, Glen E.

2014-01-01

Precise measurement of physical activity is important for health research, providing a better understanding of activity location, type, duration, and intensity. This article describes a novel suite of tools to measure and analyze physical activity behaviors in spatial epidemiology research. We use individual-level, high-resolution, objective data collected in a space-time framework to investigate built and social environment influences on activity. First, we collect data with accelerometers, global positioning system units, and smartphone-based digital travel and photo diaries to overcome many limitations inherent in self-reported data. Behaviors are measured continuously over the full spectrum of environmental exposures in daily life, instead of focusing exclusively on the home neighborhood. Second, data streams are integrated using common timestamps into a single data structure, the “LifeLog.” A graphic interface tool, “LifeLog View,” enables simultaneous visualization of all LifeLog data streams. Finally, we use geographic information system SmartMap rasters to measure spatially continuous environmental variables to capture exposures at the same spatial and temporal scale as in the LifeLog. These technologies enable precise measurement of behaviors in their spatial and temporal settings but also generate very large datasets; we discuss current limitations and promising methods for processing and analyzing such large datasets. Finally, we provide applications of these methods in spatially oriented research, including a natural experiment to evaluate the effects of new transportation infrastructure on activity levels, and a study of neighborhood environmental effects on activity using twins as quasi-causal controls to overcome self-selection and reverse causation problems. In summary, the integrative characteristics of large datasets contained in LifeLogs and SmartMaps hold great promise for advancing spatial epidemiologic research to promote healthy behaviors. PMID:24479113

Advances in Applications of Hierarchical Bayesian Methods with Hydrological Models

NASA Astrophysics Data System (ADS)

Alexander, R. B.; Schwarz, G. E.; Boyer, E. W.

2017-12-01

Mechanistic and empirical watershed models are increasingly used to inform water resource decisions. Growing access to historical stream measurements and data from in-situ sensor technologies has increased the need for improved techniques for coupling models with hydrological measurements. Techniques that account for the intrinsic uncertainties of both models and measurements are especially needed. Hierarchical Bayesian methods provide an efficient modeling tool for quantifying model and prediction uncertainties, including those associated with measurements. Hierarchical methods can also be used to explore spatial and temporal variations in model parameters and uncertainties that are informed by hydrological measurements. We used hierarchical Bayesian methods to develop a hybrid (statistical-mechanistic) SPARROW (SPAtially Referenced Regression On Watershed attributes) model of long-term mean annual streamflow across diverse environmental and climatic drainages in 18 U.S. hydrological regions. Our application illustrates the use of a new generation of Bayesian methods that offer more advanced computational efficiencies than the prior generation. Evaluations of the effects of hierarchical (regional) variations in model coefficients and uncertainties on model accuracy indicates improved prediction accuracies (median of 10-50%) but primarily in humid eastern regions, where model uncertainties are one-third of those in arid western regions. Generally moderate regional variability is observed for most hierarchical coefficients. Accounting for measurement and structural uncertainties, using hierarchical state-space techniques, revealed the effects of spatially-heterogeneous, latent hydrological processes in the "localized" drainages between calibration sites; this improved model precision, with only minor changes in regional coefficients. Our study can inform advances in the use of hierarchical methods with hydrological models to improve their integration with stream measurements.

Single-walled carbon nanotubes as near-infrared optical biosensors for life sciences and biomedicine.

PubMed

Jain, Astha; Homayoun, Aida; Bannister, Christopher W; Yum, Kyungsuk

2015-03-01

Single-walled carbon nanotubes that emit photostable near-infrared fluorescence have emerged as near-infrared optical biosensors for life sciences and biomedicine. Since the discovery of their near-infrared fluorescence, researchers have engineered single-walled carbon nanotubes to function as an optical biosensor that selectively modulates its fluorescence upon binding of target molecules. Here we review the recent advances in the single-walled carbon nanotube-based optical sensing technology for life sciences and biomedicine. We discuss the structure and optical properties of single-walled carbon nanotubes, the mechanisms for molecular recognition and signal transduction in single-walled carbon nanotube complexes, and the recent development of various single-walled carbon nanotube-based optical biosensors. We also discuss the opportunities and challenges to translate this emerging technology into biomedical research and clinical use, including the biological safety of single-walled carbon nanotubes. The advances in single-walled carbon nanotube-based near-infrared optical sensing technology open up a new avenue for in vitro and in vivo biosensing with high sensitivity and high spatial resolution, beneficial for many areas of life sciences and biomedicine. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Los Alamos NEP research in advanced plasma thrusters

NASA Technical Reports Server (NTRS)

Schoenberg, Kurt; Gerwin, Richard

1991-01-01

Research was initiated in advanced plasma thrusters that capitalizes on lab capabilities in plasma science and technology. The goal of the program was to examine the scaling issues of magnetoplasmadynamic (MPD) thruster performance in support of NASA's MPD thruster development program. The objective was to address multi-megawatt, large scale, quasi-steady state MPD thruster performance. Results to date include a new quasi-steady state operating regime which was obtained at space exploration initiative relevant power levels, that enables direct coaxial gun-MPD comparisons of thruster physics and performance. The radiative losses are neglible. Operation with an applied axial magnetic field shows the same operational stability and exhaust plume uniformity benefits seen in MPD thrusters. Observed gun impedance is in close agreement with the magnetic Bernoulli model predictions. Spatial and temporal measurements of magnetic field, electric field, plasma density, electron temperature, and ion/neutral energy distribution are underway. Model applications to advanced mission logistics are also underway.

Applications of iQID cameras

NASA Astrophysics Data System (ADS)

Han, Ling; Miller, Brian W.; Barrett, Harrison H.; Barber, H. Bradford; Furenlid, Lars R.

2017-09-01

iQID is an intensified quantum imaging detector developed in the Center for Gamma-Ray Imaging (CGRI). Originally called BazookaSPECT, iQID was designed for high-resolution gamma-ray imaging and preclinical gamma-ray single-photon emission computed tomography (SPECT). With the use of a columnar scintillator, an image intensifier and modern CCD/CMOS sensors, iQID cameras features outstanding intrinsic spatial resolution. In recent years, many advances have been achieved that greatly boost the performance of iQID, broadening its applications to cover nuclear and particle imaging for preclinical, clinical and homeland security settings. This paper presents an overview of the recent advances of iQID technology and its applications in preclinical and clinical scintigraphy, preclinical SPECT, particle imaging (alpha, neutron, beta, and fission fragment), and digital autoradiography.

Agricultural practices and irrigation water demand in Uttar Pradesh

NASA Astrophysics Data System (ADS)

O'Keeffe, J.; Buytaert, W.; Brozovic, N.; Mijic, A.

2013-12-01

Changes in farming practices within Uttar Pradesh, particularly advances in irrigation technology, have led to a significant drop in water tables across the region. While the acquisition of monitoring data in India is a challenge, current water use practices point towards water overdraught. This is exacerbated by government and state policies and practices, including the subsidising of electricity, seeds and fertilizer, and an agreement to buy all crops grown, promoting the over use of water resources. Taking India's predicted population growth, increases in industrialisation and climate change into account, both farmland and the water resources it depends upon will be subject to increased pressures in the future. This research is centred around irrigation demands on water resources within Uttar Pradesh, and in particular, quantifying those demands both spatially and temporally. Two aspects of this will be presented; the quantification of irrigation water applied and the characterisation of the spatial heterogeneity of water use practices. Calculating the volumes of applied irrigation water in the absence of observed data presents a major challenge and is achieved here through the use of crop models. Regional crop yields provided by statistical yearbooks are replicated by the crop models AquaCrop and InfoCrop, and by doing so the amount of irrigation water needed to produce the published yields is quantified. In addition, proxy information, for example electrical consumption for agricultural use, is used to verify the likely volumes of water abstracted from tubewells. Statistical analyses of borehole distribution and the characterisation of the spatial heterogeneity of water use practices, particularly farmer decision making, collected during a field trip are also presented. The evolution of agricultural practices, technological advancement and water use for irrigation is reconstructed through the use of multiple regression and principle component analysis, allowing the identification of drivers of current water use practices. The importance of undertaking this research to model set up and for the advancement of overall understanding of the hydrological system is emphasised along with its significance in developing policy and informing water allocation models; a platform for more sustainable future water resource management in the region.

Quantitative metrics for assessment of chemical image quality and spatial resolution

DOE PAGES

Kertesz, Vilmos; Cahill, John F.; Van Berkel, Gary J.

2016-02-28

Rationale: Currently objective/quantitative descriptions of the quality and spatial resolution of mass spectrometry derived chemical images are not standardized. Development of these standardized metrics is required to objectively describe chemical imaging capabilities of existing and/or new mass spectrometry imaging technologies. Such metrics would allow unbiased judgment of intra-laboratory advancement and/or inter-laboratory comparison for these technologies if used together with standardized surfaces. Methods: We developed two image metrics, viz., chemical image contrast (ChemIC) based on signal-to-noise related statistical measures on chemical image pixels and corrected resolving power factor (cRPF) constructed from statistical analysis of mass-to-charge chronograms across features of interest inmore » an image. These metrics, quantifying chemical image quality and spatial resolution, respectively, were used to evaluate chemical images of a model photoresist patterned surface collected using a laser ablation/liquid vortex capture mass spectrometry imaging system under different instrument operational parameters. Results: The calculated ChemIC and cRPF metrics determined in an unbiased fashion the relative ranking of chemical image quality obtained with the laser ablation/liquid vortex capture mass spectrometry imaging system. These rankings were used to show that both chemical image contrast and spatial resolution deteriorated with increasing surface scan speed, increased lane spacing and decreasing size of surface features. Conclusions: ChemIC and cRPF, respectively, were developed and successfully applied for the objective description of chemical image quality and spatial resolution of chemical images collected from model surfaces using a laser ablation/liquid vortex capture mass spectrometry imaging system.« less

Quantitative metrics for assessment of chemical image quality and spatial resolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kertesz, Vilmos; Cahill, John F.; Van Berkel, Gary J.

Rationale: Currently objective/quantitative descriptions of the quality and spatial resolution of mass spectrometry derived chemical images are not standardized. Development of these standardized metrics is required to objectively describe chemical imaging capabilities of existing and/or new mass spectrometry imaging technologies. Such metrics would allow unbiased judgment of intra-laboratory advancement and/or inter-laboratory comparison for these technologies if used together with standardized surfaces. Methods: We developed two image metrics, viz., chemical image contrast (ChemIC) based on signal-to-noise related statistical measures on chemical image pixels and corrected resolving power factor (cRPF) constructed from statistical analysis of mass-to-charge chronograms across features of interest inmore » an image. These metrics, quantifying chemical image quality and spatial resolution, respectively, were used to evaluate chemical images of a model photoresist patterned surface collected using a laser ablation/liquid vortex capture mass spectrometry imaging system under different instrument operational parameters. Results: The calculated ChemIC and cRPF metrics determined in an unbiased fashion the relative ranking of chemical image quality obtained with the laser ablation/liquid vortex capture mass spectrometry imaging system. These rankings were used to show that both chemical image contrast and spatial resolution deteriorated with increasing surface scan speed, increased lane spacing and decreasing size of surface features. Conclusions: ChemIC and cRPF, respectively, were developed and successfully applied for the objective description of chemical image quality and spatial resolution of chemical images collected from model surfaces using a laser ablation/liquid vortex capture mass spectrometry imaging system.« less

Devices for visually impaired people: High technological devices with low user acceptance and no adaptability for children.

PubMed

Gori, Monica; Cappagli, Giulia; Tonelli, Alessia; Baud-Bovy, Gabriel; Finocchietti, Sara

2016-10-01

Considering that cortical plasticity is maximal in the child, why are the majority of technological devices available for visually impaired users meant for adults and not for children? Moreover, despite high technological advancements in recent years, why is there still no full user acceptance of existing sensory substitution devices? The goal of this review is to create a link between neuroscientists and engineers by opening a discussion about the direction that the development of technological devices for visually impaired people is taking. Firstly, we review works on spatial and social skills in children with visual impairments, showing that lack of vision is associated with other sensory and motor delays. Secondly, we present some of the technological solutions developed to date for visually impaired people. Doing this, we highlight the core features of these systems and discuss their limits. We also discuss the possible reasons behind the low adaptability in children. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Integration of Hydrogeophysical Datasets for Improved Water Resource Management in Irrigated Systems

NASA Astrophysics Data System (ADS)

Finkenbiner, C. E.; Franz, T. E.; Heeren, D.; Gibson, J. P.; Russell, M. V.

2016-12-01

With an average irrigation water use efficiency of approximately 45% in the United States, improvements in water management can be made within agricultural systems. Advancements in precision irrigation technologies allow application rates and times to vary within a field. Current limitations in applying these technologies are often attributed to the quantification of soil spatial variability. This work aims to increase our understanding of soil hydrologic fluxes at intermediate spatial scales. Field capacity and wilting point values for a field near Sutherland, NE were downloaded from the USDA SSURGO database. Stationary and roving cosmic-ray neutron probes (CRNP) (sensor measurement volume of 300 m radius sphere and 30 cm vertical soil depth) were combined in order to characterize the spatial and temporal patterns of soil moisture at the site. We used a data merging technique to produce a statistical daily soil moisture product at a range of key spatial scales in support of current irrigation technologies: the individual sprinkler ( 102 m2) for variable rate irrigation, the individual wedge ( 103 m2) for variable speed irrigation, and the quarter section (0.82 km2) for uniform rate irrigation. The results show our CRNP "observed" field capacity was higher compared to the SSURGO products. The measured hydraulic properties from sixty-two soil cores collected from the field correlate well with our "observed" CRNP values. We hypothesize that our results, when provided to irrigators, will decrease water losses due to runoff and deep percolation as sprinkler managers can better estimate irrigation application depths and times in relation to soil moisture depletion below field capacity and above maximum allowable depletion. The incorporation of the CRNP into current irrigation practices has the potential to greatly increase agricultural water use efficiency. Moreover, the defined soil hydraulic properties at various spatial scales offers additional valuable datasets for the land surface modeling community.

Integrating natural language processing and web GIS for interactive knowledge domain visualization

NASA Astrophysics Data System (ADS)

Du, Fangming

Recent years have seen a powerful shift towards data-rich environments throughout society. This has extended to a change in how the artifacts and products of scientific knowledge production can be analyzed and understood. Bottom-up approaches are on the rise that combine access to huge amounts of academic publications with advanced computer graphics and data processing tools, including natural language processing. Knowledge domain visualization is one of those multi-technology approaches, with its aim of turning domain-specific human knowledge into highly visual representations in order to better understand the structure and evolution of domain knowledge. For example, network visualizations built from co-author relations contained in academic publications can provide insight on how scholars collaborate with each other in one or multiple domains, and visualizations built from the text content of articles can help us understand the topical structure of knowledge domains. These knowledge domain visualizations need to support interactive viewing and exploration by users. Such spatialization efforts are increasingly looking to geography and GIS as a source of metaphors and practical technology solutions, even when non-georeferenced information is managed, analyzed, and visualized. When it comes to deploying spatialized representations online, web mapping and web GIS can provide practical technology solutions for interactive viewing of knowledge domain visualizations, from panning and zooming to the overlay of additional information. This thesis presents a novel combination of advanced natural language processing - in the form of topic modeling - with dimensionality reduction through self-organizing maps and the deployment of web mapping/GIS technology towards intuitive, GIS-like, exploration of a knowledge domain visualization. A complete workflow is proposed and implemented that processes any corpus of input text documents into a map form and leverages a web application framework to let users explore knowledge domain maps interactively. This workflow is implemented and demonstrated for a data set of more than 66,000 conference abstracts.

A review on technologies and their usage in solid waste monitoring and management systems: Issues and challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hannan, M.A., E-mail: hannan@eng.ukm.my; Abdulla Al Mamun, Md., E-mail: md.abdulla@siswa.ukm.edu.my; Hussain, Aini, E-mail: aini@eng.ukm.my

Highlights: • Classification of available technologies for SWM system in four core category. • Organization of technology based SWM systems in three main groups. • Summary of SWM systems with target application, methodology and functional domain. • Issues and challenges are highlighted for further design of a sustainable system. - Abstract: In the backdrop of prompt advancement, information and communication technology (ICT) has become an inevitable part to plan and design of modern solid waste management (SWM) systems. This study presents a critical review of the existing ICTs and their usage in SWM systems to unfold the issues and challengesmore » towards using integrated technologies based system. To plan, monitor, collect and manage solid waste, the ICTs are divided into four categories such as spatial technologies, identification technologies, data acquisition technologies and data communication technologies. The ICT based SWM systems classified in this paper are based on the first three technologies while the forth one is employed by almost every systems. This review may guide the reader about the basics of available ICTs and their application in SWM to facilitate the search for planning and design of a sustainable new system.« less

Technological evaluation of gesture and speech interfaces for enabling dismounted soldier-robot dialogue

NASA Astrophysics Data System (ADS)

Kattoju, Ravi Kiran; Barber, Daniel J.; Abich, Julian; Harris, Jonathan

2016-05-01

With increasing necessity for intuitive Soldier-robot communication in military operations and advancements in interactive technologies, autonomous robots have transitioned from assistance tools to functional and operational teammates able to service an array of military operations. Despite improvements in gesture and speech recognition technologies, their effectiveness in supporting Soldier-robot communication is still uncertain. The purpose of the present study was to evaluate the performance of gesture and speech interface technologies to facilitate Soldier-robot communication during a spatial-navigation task with an autonomous robot. Gesture and speech semantically based spatial-navigation commands leveraged existing lexicons for visual and verbal communication from the U.S Army field manual for visual signaling and a previously established Squad Level Vocabulary (SLV). Speech commands were recorded by a Lapel microphone and Microsoft Kinect, and classified by commercial off-the-shelf automatic speech recognition (ASR) software. Visual signals were captured and classified using a custom wireless gesture glove and software. Participants in the experiment commanded a robot to complete a simulated ISR mission in a scaled down urban scenario by delivering a sequence of gesture and speech commands, both individually and simultaneously, to the robot. Performance and reliability of gesture and speech hardware interfaces and recognition tools were analyzed and reported. Analysis of experimental results demonstrated the employed gesture technology has significant potential for enabling bidirectional Soldier-robot team dialogue based on the high classification accuracy and minimal training required to perform gesture commands.

Remote sensing of vegetation structure using computer vision

NASA Astrophysics Data System (ADS)

Dandois, Jonathan P.

High-spatial resolution measurements of vegetation structure are needed for improving understanding of ecosystem carbon, water and nutrient dynamics, the response of ecosystems to a changing climate, and for biodiversity mapping and conservation, among many research areas. Our ability to make such measurements has been greatly enhanced by continuing developments in remote sensing technology---allowing researchers the ability to measure numerous forest traits at varying spatial and temporal scales and over large spatial extents with minimal to no field work, which is costly for large spatial areas or logistically difficult in some locations. Despite these advances, there remain several research challenges related to the methods by which three-dimensional (3D) and spectral datasets are joined (remote sensing fusion) and the availability and portability of systems for frequent data collections at small scale sampling locations. Recent advances in the areas of computer vision structure from motion (SFM) and consumer unmanned aerial systems (UAS) offer the potential to address these challenges by enabling repeatable measurements of vegetation structural and spectral traits at the scale of individual trees. However, the potential advances offered by computer vision remote sensing also present unique challenges and questions that need to be addressed before this approach can be used to improve understanding of forest ecosystems. For computer vision remote sensing to be a valuable tool for studying forests, bounding information about the characteristics of the data produced by the system will help researchers understand and interpret results in the context of the forest being studied and of other remote sensing techniques. This research advances understanding of how forest canopy and tree 3D structure and color are accurately measured by a relatively low-cost and portable computer vision personal remote sensing system: 'Ecosynth'. Recommendations are made for optimal conditions under which forest structure measurements should be obtained with UAS-SFM remote sensing. Ultimately remote sensing of vegetation by computer vision offers the potential to provide an 'ecologist's eye view', capturing not only canopy 3D and spectral properties, but also seeing the trees in the forest and the leaves on the trees.

New 2-D dosimetric technique for radiotherapy based on planar thermoluminescent detectors.

PubMed

Olko, P; Marczewska, B; Czopyk, L; Czermak, M A; Klosowski, M; Waligórski, M P R

2006-01-01

At the Institute of Nuclear Physics of the Polish Academy of Sciences (IFJ) in Kraków, a two-dimensional (2-D) thermoluminescence (TL) dosimetry system was developed within the MAESTRO (Methods and Advanced Equipment for Simulation and Treatment in Radio-Oncology) 6 Framework Programme and tested by evaluating 2-D dose distributions around radioactive sources. A thermoluminescent detector (TLD) foil was developed, of thickness 0.3 mm and diameter 60 mm, containing a mixture of highly sensitive LiF:Mg,Cu,P powder and Ethylene TetraFluoroEthylene (ETFE) polymer. Foil detectors were irradiated with (226)Ra brachytherapy sources and a (90)Sr/(90)Y source. 2-D dose distributions were evaluated using a prototype planar (diameter 60 mm) reader, equipped with a 12 bit Charge Coupled Devices (CCD) PCO AG camera, with a resolution of 640 x 480 pixels. The new detectors, showing a spatial resolution better than 0.5 mm and a measurable dose range typical for radiotherapy, can find many applications in clinical dosimetry. Another technology applicable to clinical dosimetry, also developed at IFJ, is the Si microstrip detector of size 95 x 95 mm(2), which may be used to evaluate the dose distribution with a spatial resolution of 120 microm along one direction, in real-time mode. The microstrip and TLD technology will be further improved, especially to develop detectors of larger area, and to make them applicable to some advanced radiotherapy modalities, such as intensity modulated radiotherapy (IMRT) or proton radiotherapy.

Cubesats and drones: bridging the spatio-temporal divide for enhanced earth observation

NASA Astrophysics Data System (ADS)

McCabe, M. F.; Aragon, B.; Parkes, S. D.; Mascaro, J.; Houborg, R.

2017-12-01

In just the last few years, a range of advances in remote sensing technologies have enabled an unprecedented opportunity in earth observation. Parallel developments in cubesats and unmanned aerial vehicles (UAVs) have overcome one of the outstanding challenges in observing the land surface: the provision of timely retrievals at a spatial resolution that is sufficiently detailed to make field-level decisions. Planet cubesats have revolutionized observing capacity through their objective of near daily global retrieval. These nano-satellite systems provide high resolution (approx. 3 m) retrievals in red-green-blue and near-infrared wavelengths, offering capacity to develop vegetation metrics for both hydrological and precision agricultural applications. Apart from satellite based advances, nearer to earth technology is being exploited for a range of observation needs. UAVs provide an adaptable platform from which a variety of sensing systems can be deployed. Combinations of optical, thermal, multi- and hyper-spectral systems allow for the estimation of a range of land surface variables, including vegetation structure, vegetation health, land surface temperature and evaporation. Here we explore some of these exciting developments in the context of agricultural hydrology, providing examples of cubesat and UAV imagery that has been used to inform upon crop health and water use. An investigation of the spatial and temporal advantage of these complementary systems is undertaken, with examples of multi-day high-resolution vegetation dynamics from cubesats presented alongside diurnal-cycle responses derived from multiple within-day UAV flights.

Collaborative classification of hyperspectral and visible images with convolutional neural network

NASA Astrophysics Data System (ADS)

Zhang, Mengmeng; Li, Wei; Du, Qian

2017-10-01

Recent advances in remote sensing technology have made multisensor data available for the same area, and it is well-known that remote sensing data processing and analysis often benefit from multisource data fusion. Specifically, low spatial resolution of hyperspectral imagery (HSI) degrades the quality of the subsequent classification task while using visible (VIS) images with high spatial resolution enables high-fidelity spatial analysis. A collaborative classification framework is proposed to fuse HSI and VIS images for finer classification. First, the convolutional neural network model is employed to extract deep spectral features for HSI classification. Second, effective binarized statistical image features are learned as contextual basis vectors for the high-resolution VIS image, followed by a classifier. The proposed approach employs diversified data in a decision fusion, leading to an integration of the rich spectral information, spatial information, and statistical representation information. In particular, the proposed approach eliminates the potential problems of the curse of dimensionality and excessive computation time. The experiments evaluated on two standard data sets demonstrate better classification performance offered by this framework.

Visualization and interaction tools for aerial photograph mosaics

NASA Astrophysics Data System (ADS)

Fernandes, João Pedro; Fonseca, Alexandra; Pereira, Luís; Faria, Adriano; Figueira, Helder; Henriques, Inês; Garção, Rita; Câmara, António

1997-05-01

This paper describes the development of a digital spatial library based on mosaics of digital orthophotos, called Interactive Portugal, that will enable users both to retrieve geospatial information existing in the Portuguese National System for Geographic Information World Wide Web server, and to develop local databases connected to the main system. A set of navigation, interaction, and visualization tools are proposed and discussed. They include sketching, dynamic sketching, and navigation capabilities over the digital orthophotos mosaics. Main applications of this digital spatial library are pointed out and discussed, namely for education, professional, and tourism markets. Future developments are considered. These developments are related to user reactions, technological advancements, and projects that also aim at delivering and exploring digital imagery on the World Wide Web. Future capabilities for site selection and change detection are also considered.

Improved signal recovery for flow cytometry based on ‘spatially modulated emission’

NASA Astrophysics Data System (ADS)

Quint, S.; Wittek, J.; Spang, P.; Levanon, N.; Walther, T.; Baßler, M.

2017-09-01

Recently, the technique of ‘spatially modulated emission’ has been introduced (Baßler et al 2008 US Patent 0080181827A1; Kiesel et al 2009 Appl. Phys. Lett. 94 041107; Kiesel et al 2011 Cytometry A 79A 317-24) improving the signal-to-noise ratio (SNR) for detecting bio-particles in the field of flow cytometry. Based on this concept, we developed two advanced signal processing methods which further enhance the SNR and selectivity for cell detection. The improvements are achieved by adapting digital filtering methods from RADAR technology and mainly address inherent offset elimination, increased signal dynamics and moreover reduction of erroneous detections due to processing artifacts. We present a comprehensive theory on SNR gain and provide experimental results of our concepts.

Management of Guidance, Navigation and Control Technologies for Spacecraft Formations under the NASA Cross-Enterprise Technology Development Program (CETDP)

NASA Technical Reports Server (NTRS)

Hartman, Kathy; Weidow, David; Hadaegh, Fred

1999-01-01

Breakthrough technology development is critical to securing the future of our space industry. The National Aeronautics and Space Administration (NASA) Cross-Enterprise Technology Development Program (CETDP) is developing critical space technologies that enable innovative and less costly missions, and spawn new mission opportunities through revolutionary, long-term, high-risk, high-payoff technology advances. The CETDP is a NASA-wide activity managed by the Advanced Technology and Mission Studies Division (AT&MS) at Headquarters Office of Space Science. Program management for CETDP is distributed across the multiple NASA Centers and draws on expertise throughout the Agency. The technology research activities are organized along Project-level divisions called thrust areas that are directly linked to the Agency's goals and objectives of the Enterprises: Earth Science, Space Science, Human Exploration and Development of Space; and the Office of the Chief Technologist's (OCT) strategic technology areas. Cross-Enterprise technology is defined as long-range strategic technologies that have broad potential to span the needs of more than one Enterprise. Technology needs are identified and prioritized by each of the primary customers. The thrust area manager (TAM) for each division is responsible for the ultimate success of technologies within their area, and can draw from industry, academia, other government agencies, other CETDP thrust areas, and other NASA Centers to accomplish the goals of the thrust area. An overview of the CETDP and description of the future directions of the thrust area called Distributed Spacecraft are presented in this paper. Revolutionary technologies developed within this thrust area will enable the implementation of a spatially distributed network of individual vehicles, or assets, collaborating as a single collective unit, and exhibiting a common system-wide capability to accomplish a shared objective. With such a capability, new Earth and space science measurement concepts become a reality.

Management of Guidance, Navigation, and Control Technologies for Spacecraft Formations Under the NASA Cross Enterprise Technology Development Program (CETDP)

NASA Technical Reports Server (NTRS)

Hartman, Kathy; Weidow, David; Hadaegh, Fred

1999-01-01

Breakthrough technology development is critical to securing the future of our space industry. The National Aeronautics and Space Administration (NASA) Cross-Enterprise Technology Development Program (CETDP) is developing critical space technologies that enable innovative and less costly missions, and spawn new mission opportunities through revolutionary, long-term, high-risk, high-payoff technology advances. The CETDP is a NASA-wide activity managed by the Advanced Technology and Mission Studies Division (AT&MS) at Headquarters Office of Space Science. Program management for CETDP is distributed across the multiple NASA Centers and draws on expertise throughout the Agency. The technology research activities are organized along Project-level divisions called thrust areas that are directly linked to the Agency's goals and objectives of the Enterprises: Earth Science, Space Science, Human Exploration and Development of Space; and the Office of the Chief Technologist's (OCT) strategic technology areas. Cross-Enterprise technology is defined as long-range strategic technologies that have broad potential to span the needs of more than one Enterprise. Technology needs are identified and prioritized by each of the primary customers. The thrust area manager (TAM) for each division is responsible for the ultimate success of technologies within their area, and can draw from industry, academia, other government agencies, other CETDP thrust areas, and other NASA Centers to accomplish the goals of the thrust area. An overview of the CETDP and description of the future directions of the thrust area called Distributed Spacecraft are presented in this paper. Revolutionary technologies developed within this thrust area will enable the implementation of a spatially distributed network of individual vehicles, or assets, collaborating as a single collective unit, and exhibiting a common system-wide capability to accomplish a shared objective. With such a capability, new Earth and space science measurement concepts become a reality.

Preliminary frequency-domain analysis for the reconstructed spatial resolution of muon tomography

NASA Astrophysics Data System (ADS)

Yu, B.; Zhao, Z.; Wang, X.; Wang, Y.; Wu, D.; Zeng, Z.; Zeng, M.; Yi, H.; Luo, Z.; Yue, X.; Cheng, J.

2014-11-01

Muon tomography is an advanced technology to non-destructively detect high atomic number materials. It exploits the multiple Coulomb scattering information of muon to reconstruct the scattering density image of the traversed object. Because of the statistics of muon scattering, the measurement error of system and the data incompleteness, the reconstruction is always accompanied with a certain level of interference, which will influence the reconstructed spatial resolution. While statistical noises can be reduced by extending the measuring time, system parameters determine the ultimate spatial resolution that one system can reach. In this paper, an effective frequency-domain model is proposed to analyze the reconstructed spatial resolution of muon tomography. The proposed method modifies the resolution analysis in conventional computed tomography (CT) to fit the different imaging mechanism in muon scattering tomography. The measured scattering information is described in frequency domain, then a relationship between the measurements and the original image is proposed in Fourier domain, which is named as "Muon Central Slice Theorem". Furthermore, a preliminary analytical expression of the ultimate reconstructed spatial is derived, and the simulations are performed for validation. While the method is able to predict the ultimate spatial resolution of a given system, it can also be utilized for the optimization of system design and construction.

The connectomics challenge

PubMed Central

Silvestri, Ludovico; Sacconi, Leonardo; Pavone, Francesco Saverio

Summary One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation. Many different approaches, ranging from electron and optical microscopy to magnetic resonance imaging, have been proposed to address the connectomics challenge on various spatial scales and in different species. Here, we review the main technological advances in the microscopy techniques applied to connectomics, highlighting the potential and limitations of the different methods. Finally, we briefly discuss the role of connectomics in the Human Brain Project, the Future and Emerging Technologies (FET) Flagship recently approved by the European Commission. PMID:24139653

[Possibilities of modern imaging technologies in early diagnosis of Alzheimer disease].

PubMed

Unschuld, Paul G

2015-04-01

Recent advances in neuroimaging technology and image analysis algorithms have significantly contributed to a better understanding of spatial and temporal aspects of brain change associated with Alzheimer Disease. The current review will demonstrate how functional (fMRI) and structural magnetic resonance imaging (MRI) techniques may be used to identify distinct patterns of brain change associated with disease progression and also increased risk for Alzheimer Disease. Moreover, Positron Emission Tomography (PET) based measures of glucosemetabolism (Fluorodeoxyglucose, FDG) and Amyloid-beta plaque density (11-C-Pittsburgh Compound B, PiB and 18-F) will be reviewed regarding their diagnostic value for assessing the individual degree of Alzheimer -pathology and thus complement the information provided by MRI and other clinical measures.

Research on key technology of space laser communication network

NASA Astrophysics Data System (ADS)

Chang, Chengwu; Huang, Huiming; Liu, Hongyang; Gao, Shenghua; Cheng, Liyu

2016-10-01

Since the 21st century, Spatial laser communication has made a breakthrough development. Europe, the United States, Japan and other space powers have carried out the test of spatial laser communication technology on-orbit, and put forward a series of plans. In 2011, China made the first technology demonstration of satellite-ground laser communication carried by HY-2 satellite. Nowadays, in order to improve the transmission rate of spatial network, the topic of spatial laser communication network is becoming a research hotspot at home and abroad. This thesis, from the basic problem of spatial laser communication network to solve, analyzes the main difference between spatial network and ground network, which draws forth the key technology of spatial laser communication backbone network, and systematically introduces our research on aggregation, addressing, architecture of spatial network. From the perspective of technology development status and trends, the thesis proposes the development route of spatial laser communication network in stages. So as to provide reference about the development of spatial laser communication network in China.

Challenges and Recent Developments in Hearing Aids: Part I. Speech Understanding in Noise, Microphone Technologies and Noise Reduction Algorithms

PubMed Central

Chung, King

2004-01-01

This review discusses the challenges in hearing aid design and fitting and the recent developments in advanced signal processing technologies to meet these challenges. The first part of the review discusses the basic concepts and the building blocks of digital signal processing algorithms, namely, the signal detection and analysis unit, the decision rules, and the time constants involved in the execution of the decision. In addition, mechanisms and the differences in the implementation of various strategies used to reduce the negative effects of noise are discussed. These technologies include the microphone technologies that take advantage of the spatial differences between speech and noise and the noise reduction algorithms that take advantage of the spectral difference and temporal separation between speech and noise. The specific technologies discussed in this paper include first-order directional microphones, adaptive directional microphones, second-order directional microphones, microphone matching algorithms, array microphones, multichannel adaptive noise reduction algorithms, and synchrony detection noise reduction algorithms. Verification data for these technologies, if available, are also summarized. PMID:15678225

The Taxiway Navigation and Situation Awareness (T-NASA) System

NASA Technical Reports Server (NTRS)

Foyle, David C.; Sridhar, Banavar (Technical Monitor)

1997-01-01

The goal of NASA's Terminal Area Productivity (TAP) Low-Visibility Landing and Surface Operations (LVLASO) subelement is to improve the efficiency of airport surface operations for commercial aircraft operating in weather conditions to Category IIIB while maintaining a high degree of safety. Currently, surface operations are one of the least technologically sophisticated components of the air transport system, being conducted in the 1990's with the same basic technology as in the 1930's. Pilots are given little or no explicit information about their current position, and routing information is limited to ATC communications and airport charts. In TAP/LVLASO, advanced technologies such as satellite navigation systems, digital data communications, advanced information presentation technology, and ground surveillance systems will be integrated into flight deck displays to enable expeditious and safe traffic movement on the airport surface. The cockpit display suite is called the T-NASA (Taxiway Navigation and Situation Awareness) System. This system has three integrated components: 1) Moving Map track-up airport surface display with own-ship, traffic and graphical route guidance 2) Scene-Linked Symbology - route/taxi information virtually projected via a Head-up Display (HUD) onto the forward scene; and, 3) 3-D Audio Ground Collision Avoidance and Navigation system - spatially-localized auditory traffic and navigation alerts. In the current paper, the design philosophy of the T-NASA system will be presented, and the T-NASA system display components described.

Quantitative Imaging of Gut Microbiota Spatial Organization

PubMed Central

Earle, Kristen A.; Billings, Gabriel; Sigal, Michael; Lichtman, Joshua S.; Hansson, Gunnar C.; Elias, Joshua E.; Amieva, Manuel R.; Huang, Kerwyn Casey; Sonnenburg, Justin L.

2015-01-01

Summary Genomic technologies have significantly advanced our understanding of the composition and diversity of host-associated microbial populations. However, their spatial organization and functional interactions relative to the host have been more challenging to study. Here we present a pipeline for the assessment of intestinal microbiota localization within immunofluorescence images of fixed gut cross-sections that includes a flexible software package, BacSpace, for high-throughput quantification of microbial organization. Applying this pipeline to gnotobiotic and human microbiota-colonized mice, we demonstrate that elimination of microbiota accessible carbohydrates (MACs) from the diet results in thinner mucus in the distal colon, increased proximity of microbes to the epithelium, and heightened expression of the inflammatory marker REG3β. Measurements of microbe-microbe proximity reveal that a MAC-deficient diet alters monophyletic spatial clustering. Furthermore, we quantify the invasion of Helicobacter pylori into the glands of the mouse stomach relative to host mitotic progenitor cells, illustrating the generalizability of this approach. PMID:26439864

Analysis of the impact of spatial resolution on land/water classifications using high-resolution aerial imagery

USGS Publications Warehouse

Enwright, Nicholas M.; Jones, William R.; Garber, Adrienne L.; Keller, Matthew J.

2014-01-01

Long-term monitoring efforts often use remote sensing to track trends in habitat or landscape conditions over time. To most appropriately compare observations over time, long-term monitoring efforts strive for consistency in methods. Thus, advances and changes in technology over time can present a challenge. For instance, modern camera technology has led to an increasing availability of very high-resolution imagery (i.e. submetre and metre) and a shift from analogue to digital photography. While numerous studies have shown that image resolution can impact the accuracy of classifications, most of these studies have focused on the impacts of comparing spatial resolution changes greater than 2 m. Thus, a knowledge gap exists on the impacts of minor changes in spatial resolution (i.e. submetre to about 1.5 m) in very high-resolution aerial imagery (i.e. 2 m resolution or less). This study compared the impact of spatial resolution on land/water classifications of an area dominated by coastal marsh vegetation in Louisiana, USA, using 1:12,000 scale colour-infrared analogue aerial photography (AAP) scanned at four different dot-per-inch resolutions simulating ground sample distances (GSDs) of 0.33, 0.54, 1, and 2 m. Analysis of the impact of spatial resolution on land/water classifications was conducted by exploring various spatial aspects of the classifications including density of waterbodies and frequency distributions in waterbody sizes. This study found that a small-magnitude change (1–1.5 m) in spatial resolution had little to no impact on the amount of water classified (i.e. percentage mapped was less than 1.5%), but had a significant impact on the mapping of very small waterbodies (i.e. waterbodies ≤ 250 m2). These findings should interest those using temporal image classifications derived from very high-resolution aerial photography as a component of long-term monitoring programs.

Intelligent infrastructure for sustainable potable water: a roundtable for emerging transnational research and technology development needs.

PubMed

Adriaens, Peter; Goovaerts, Pierre; Skerlos, Steven; Edwards, Elizabeth; Egli, Thomas

2003-12-01

Recent commercial and residential development have substantially impacted the fluxes and quality of water that recharge the aquifers and discharges to streams, lakes and wetlands and, ultimately, is recycled for potable use. Whereas the contaminant sources may be varied in scope and composition, these issues of urban water sustainability are of public health concern at all levels of economic development worldwide, and require cheap and innovative environmental sensing capabilities and interactive monitoring networks, as well as tailored distributed water treatment technologies. To address this need, a roundtable was organized to explore the potential role of advances in biotechnology and bioengineering to aid in developing causative relationships between spatial and temporal changes in urbanization patterns and groundwater and surface water quality parameters, and to address aspects of socioeconomic constraints in implementing sustainable exploitation of water resources. An interactive framework for quantitative analysis of the coupling between human and natural systems requires integrating information derived from online and offline point measurements with Geographic Information Systems (GIS)-based remote sensing imagery analysis, groundwater-surface water hydrologic fluxes and water quality data to assess the vulnerability of potable water supplies. Spatially referenced data to inform uncertainty-based dynamic models can be used to rank watershed-specific stressors and receptors to guide researchers and policymakers in the development of targeted sensing and monitoring technologies, as well as tailored control measures for risk mitigation of potable water from microbial and chemical environmental contamination. The enabling technologies encompass: (i) distributed sensing approaches for microbial and chemical contamination (e.g. pathogens, endocrine disruptors); (ii) distributed application-specific, and infrastructure-adaptive water treatment systems; (iii) geostatistical integration of monitoring data and GIS layers; and (iv) systems analysis of microbial and chemical proliferation in distribution systems. This operational framework is aimed at technology implementation while maximizing economic and public health benefits. The outcomes of the roundtable will further research agendas in information technology-based monitoring infrastructure development, integration of processes and spatial analysis, as well as in new educational and training platforms for students, practitioners and regulators. The potential for technology diffusion to emerging economies with limited financial resources is substantial.

[Territory and decentralization in the agenda for productive transformation with equity].

PubMed

Sojo, A

1991-08-01

The regional perspective and the decentralization in Latin American and Caribbean countries was examined in light of technological changes and transformation of economic production to boost productivity. National population policies were not the major cause of redistribution of the population, rather such transformation significantly changed the comparative regional and urban advantages in the use of territory affecting the spatial distribution of the population. Hypotheses were advanced using the transformation of production, regional development, and decentralization on the retention, attraction, and migration of population in different areas with varying economic conditions. Spurious competitiveness means global strategies of enterprises that establish foreign operations by means of factor sourcing. Flexible specialization is a company strategy of permanent innovation based on flexible equipment and a qualified work force. The increasing transnationalization of capital is the source of skills and technology that sustain competitive advantages. Decentralization can resolve local demand, facilitate access to information, mobilize resources, and exercise control over local operations. In Japan, Germany, and Italy vs. the US and France there is a social contract among companies, trade unions, universities, and regional administrations in the interest of capital and the work force. There is no direct relationship between technology and region, the industrial cluster exhibits systemic competitiveness in developed countries (the Emilian model in Italy affirms the ability of small enterprises to develop new products), the regional impact is diverse relative to new technologies (some deprived rural economic areas have potential as in central and northern Italy), and population and region are linked (regional and rural-urban differences in the growth of population and migratory flows account for spatial distribution of the population). Decentralization and systemic competitiveness concern productivity and regional policies (spatial diversity for increased productivity) and technology and human resources are interdependent (technical progress is determined by the level of qualification of the population).

Influences of geo-spatial location on pre-exposure prophylaxis use in South Africa: positioning microbicides for better product uptake.

PubMed

Govender, Eliza M; Mansoor, Leila E; Abdool Karim, Quarraisha

2017-06-01

Young women bear a disproportionately high burden of HIV infection in sub-Saharan Africa, prioritising pre-exposure prophylaxis (PrEP) can be an integral part of HIV prevention combination strategies. Women initiated HIV prevention technology options will require consistent adherence, an imperative for product effectiveness. With several PrEP clinical trials underway; exploring women's acceptability to advances in HIV prevention technologies can better facilitate demand creation for future PrEP roll out. This study utilised the opportunity of post-trial access to CAPRISA 008 women (trial) and non-trial women from three geo-spatial settings (urban, rural and peri-urban) to identify microbicide acceptability and how product associations of microbicides can influence future HIV prevention choices. Six participatory workshops using participatory action research with art-based activities and discussion groups were conducted in KwaZulu-Natal with 104 women from various geo-spatial locations and social status to understand microbicide acceptability and product associations. The data were analysed using thematic analysis. The study found that women's acceptability and product association of the tenofovir gel microbicide differed according to rural and urban areas. Most urban women identified confidence, sexiness and classiness as key associations that will encourage microbicide acceptability and use, while rural women identified respect, responsibility and confidence as the key product associations, with increased focus on the individual and collective family/community benefits of product acceptance and use. Urban-rural differences suggest a market segmentation that is contextualised to be locally responsive to promote HIV prevention technologies. Various sexual encounters further determined the types of HIV prevention technologies women would consider. In line with WHO's recommendation that PrEP should be an additional prevention choice for people at risk of HIV, this study underscores the importance of user engagement, understanding product associations and how this can influence product acceptability and promotion of HIV prevention technologies.

Optical design and development of a snapshot light-field laryngoscope

NASA Astrophysics Data System (ADS)

Zhu, Shuaishuai; Jin, Peng; Liang, Rongguang; Gao, Liang

2018-02-01

The convergence of recent advances in optical fabrication and digital processing yields a generation of imaging technology-light-field (LF) cameras which bridge the realms of applied mathematics, optics, and high-performance computing. Herein for the first time, we introduce the paradigm of LF imaging into laryngoscopy. The resultant probe can image the three-dimensional shape of vocal folds within a single camera exposure. Furthermore, to improve the spatial resolution, we developed an image fusion algorithm, providing a simple solution to a long-standing problem in LF imaging.

iGlobe Interactive Visualization and Analysis of Spatial Data

NASA Technical Reports Server (NTRS)

Hogan, Patrick

2012-01-01

iGlobe is open-source software built on NASA World Wind virtual globe technology. iGlobe provides a growing set of tools for weather science, climate research, and agricultural analysis. Up until now, these types of sophisticated tools have been developed in isolation by national agencies, academic institutions, and research organizations. By providing an open-source solution to analyze and visualize weather, climate, and agricultural data, the scientific and research communities can more readily advance solutions needed to understand better the dynamics of our home planet, Earth

An Approach of Web-based Point Cloud Visualization without Plug-in

NASA Astrophysics Data System (ADS)

Ye, Mengxuan; Wei, Shuangfeng; Zhang, Dongmei

2016-11-01

With the advances in three-dimensional laser scanning technology, the demand for visualization of massive point cloud is increasingly urgent, but a few years ago point cloud visualization was limited to desktop-based solutions until the introduction of WebGL, several web renderers are available. This paper addressed the current issues in web-based point cloud visualization, and proposed a method of web-based point cloud visualization without plug-in. The method combines ASP.NET and WebGL technologies, using the spatial database PostgreSQL to store data and the open web technologies HTML5 and CSS3 to implement the user interface, a visualization system online for 3D point cloud is developed by Javascript with the web interactions. Finally, the method is applied to the real case. Experiment proves that the new model is of great practical value which avoids the shortcoming of the existing WebGIS solutions.

Multi-scale computation methods: Their applications in lithium-ion battery research and development

NASA Astrophysics Data System (ADS)

Siqi, Shi; Jian, Gao; Yue, Liu; Yan, Zhao; Qu, Wu; Wangwei, Ju; Chuying, Ouyang; Ruijuan, Xiao

2016-01-01

Based upon advances in theoretical algorithms, modeling and simulations, and computer technologies, the rational design of materials, cells, devices, and packs in the field of lithium-ion batteries is being realized incrementally and will at some point trigger a paradigm revolution by combining calculations and experiments linked by a big shared database, enabling accelerated development of the whole industrial chain. Theory and multi-scale modeling and simulation, as supplements to experimental efforts, can help greatly to close some of the current experimental and technological gaps, as well as predict path-independent properties and help to fundamentally understand path-independent performance in multiple spatial and temporal scales. Project supported by the National Natural Science Foundation of China (Grant Nos. 51372228 and 11234013), the National High Technology Research and Development Program of China (Grant No. 2015AA034201), and Shanghai Pujiang Program, China (Grant No. 14PJ1403900).

Inflection Points in Magnetic Resonance Imaging Technology-35 Years of Collaborative Research and Development.

PubMed

Wood, Michael L; Griswold, Mark A; Henkelman, Mark; Hennig, Jürgen

2015-09-01

The technology for clinical magnetic resonance imaging (MRI) has advanced with remarkable speed and in such a manner reflecting the influence of 3 forces-collaboration between disciplines, collaboration between academia and industry, and the enabling of software applications by hardware. The forces are evident in the key developments from the past and emerging trends for the future highlighted in this review article. These developments are associated with MRI system attributes, such as wider, shorter, and stronger magnets; specialty magnets and hybrid devices; k space; and the notion that magnetic field gradients perform a Fourier transform on the spatial distribution of magnetization, phased-array coils and parallel imaging, the user interface, the wide range of contrast possible, and applications that exploit motion-induced phase shifts. An attempt is made to show connections between these developments and how the 3 forces mentioned previously will continue to shape the technology used so productively in clinical MRI.

Study on multispectral imaging detection and recognition

NASA Astrophysics Data System (ADS)

Jun, Wang; Na, Ding; Gao, Jiaobo; Yu, Hu; Jun, Wu; Li, Junna; Zheng, Yawei; Fei, Gao; Sun, Kefeng

2009-07-01

Multispectral imaging detecting technology use target radiation character in spectral spatial distribution and relation between spectral and image to detect target and remote sensing measure. Its speciality is multi channel, narrow bandwidth, large amount of information, high accuracy. The ability of detecting target in environment of clutter, camouflage, concealment and beguilement is improved. At present, spectral imaging technology in the range of multispectral and hyperspectral develop greatly. The multispectral imaging equipment of unmanned aerial vehicle can be used in mine detection, information, surveillance and reconnaissance. Spectral imaging spectrometer operating in MWIR and LWIR has already been applied in the field of remote sensing and military in the advanced country. The paper presents the technology of multispectral imaging. It can enhance the reflectance, scatter and radiation character of the artificial targets among nature background. The targets among complex background and camouflage/stealth targets can be effectively identified. The experiment results and the data of spectral imaging is obtained.

Advanced optical technologies for space exploration

NASA Astrophysics Data System (ADS)

Clark, Natalie

2007-09-01

NASA Langley Research Center is involved in the development of photonic devices and systems for space exploration missions. Photonic technologies of particular interest are those that can be utilized for in-space communication, remote sensing, guidance navigation and control, lunar descent and landing, and rendezvous and docking. NASA Langley has recently established a class-100 clean-room which serves as a Photonics Fabrication Facility for development of prototype optoelectronic devices for aerospace applications. In this paper we discuss our design, fabrication, and testing of novel active pixels, deformable mirrors, and liquid crystal spatial light modulators. Successful implementation of these intelligent optical devices and systems in space, requires careful consideration of temperature and space radiation effects in inorganic and electronic materials. Applications including high bandwidth inertial reference units, lightweight, high precision star trackers for guidance, navigation, and control, deformable mirrors, wavefront sensing, and beam steering technologies are discussed. In addition, experimental results are presented which characterize their performance in space exploration systems

Advanced Optical Technologies for Space Exploration

NASA Technical Reports Server (NTRS)

Clark, Natalie

2007-01-01

NASA Langley Research Center is involved in the development of photonic devices and systems for space exploration missions. Photonic technologies of particular interest are those that can be utilized for in-space communication, remote sensing, guidance navigation and control, lunar descent and landing, and rendezvous and docking. NASA Langley has recently established a class-100 clean-room which serves as a Photonics Fabrication Facility for development of prototype optoelectronic devices for aerospace applications. In this paper we discuss our design, fabrication, and testing of novel active pixels, deformable mirrors, and liquid crystal spatial light modulators. Successful implementation of these intelligent optical devices and systems in space, requires careful consideration of temperature and space radiation effects in inorganic and electronic materials. Applications including high bandwidth inertial reference units, lightweight, high precision star trackers for guidance, navigation, and control, deformable mirrors, wavefront sensing, and beam steering technologies are discussed. In addition, experimental results are presented which characterize their performance in space exploration systems.

Nano-Computed Tomography: Technique and Applications.

PubMed

Kampschulte, M; Langheinirch, A C; Sender, J; Litzlbauer, H D; Althöhn, U; Schwab, J D; Alejandre-Lafont, E; Martels, G; Krombach, G A

2016-02-01

Nano-computed tomography (nano-CT) is an emerging, high-resolution cross-sectional imaging technique and represents a technical advancement of the established micro-CT technology. Based on the application of a transmission target X-ray tube, the focal spot size can be decreased down to diameters less than 400 nanometers (nm). Together with specific detectors and examination protocols, a superior spatial resolution up to 400 nm (10 % MTF) can be achieved, thereby exceeding the resolution capacity of typical micro-CT systems. The technical concept of nano-CT imaging as well as the basics of specimen preparation are demonstrated exemplarily. Characteristics of atherosclerotic plaques (intraplaque hemorrhage and calcifications) in a murine model of atherosclerosis (ApoE (-/-)/LDLR(-/-) double knockout mouse) are demonstrated in the context of superior spatial resolution in comparison to micro-CT. Furthermore, this article presents the application of nano-CT for imaging cerebral microcirculation (murine), lung structures (porcine), and trabecular microstructure (ovine) in contrast to micro-CT imaging. This review shows the potential of nano-CT as a radiological method in biomedical basic research and discusses the application of experimental, high resolution CT techniques in consideration of other high resolution cross-sectional imaging techniques. Nano-computed tomography is a high resolution CT-technology for 3D imaging at sub-micrometer resolution. The technical concept bases on a further development of the established ex-vivo-micro-CT technology. By improvement of the spatial resolution, structures at a cellular level become visible (e.g. osteocyte lacunae). © Georg Thieme Verlag KG Stuttgart · New York.

Using two MEMS deformable mirrors in an adaptive optics test bed for multiconjugate correction

NASA Astrophysics Data System (ADS)

Andrews, Jonathan R.; Martinez, Ty; Teare, Scott W.; Restaino, Sergio R.; Wilcox, Christopher C.; Santiago, Freddie; Payne, Don M.

2010-02-01

Adaptive optics systems have advanced considerably over the past decade and have become common tools for optical engineers. The most recent advances in adaptive optics technology have lead to significant reductions in the cost of most of the key components. Most significantly, the cost of deformable elements and wavefront sensor components have dropped to the point where multiple deformable mirrors and Shack- Hartmann array based wavefront sensor cameras can be included in a single system. Matched with the appropriate hardware and software, formidable systems can be operating in nearly any sized research laboratory. The significant advancement of MEMS deformable mirrors has made them very popular for use as the active corrective element in multi-conjugate adaptive optics systems so that, in particular for astronomical applications, this allows correction in more than one plane. The NRL compact AO system and atmospheric simulation systems has now been expanded to support Multi Conjugate Adaptive Optics (MCAO), taking advantage of using the liquid crystal spatial light modulator (SLM) driven aberration generators in two conjugate planes that are well separated spatially. Thus, by using two SLM based aberration generators and two separate wavefront sensors, the system can measure and apply wavefront correction with two MEMS deformable mirrors. This paper describes the multi-conjugate adaptive optics system and the testing and calibration of the system and demonstrates preliminary results with this system.

Next generation miniature simultaneous multi-hyperspectral imaging systems

NASA Astrophysics Data System (ADS)

Hinnrichs, Michele; Gupta, Neelam

2014-03-01

The concept for a hyperspectral imaging system using a Fabry-Perot tunable filter (FPTF) array that is fabricated using "miniature optical electrical mechanical system" (MOEMS) technology. [1] Using an array of FPTF as an approach to hyperspectral imaging relaxes wavelength tuning requirements considerably because of the reduced portion of the spectrum that is covered by each element in the array. In this paper, Pacific Advanced Technology and ARL present the results of a concept design and performed analysis of a MOEMS based tunable Fabry-Perot array (FPTF) to perform simultaneous multispectral and hyperspectral imaging with relatively high spatial resolution. The concept design was developed with support of an Army SBIR Phase I program The Fabry-Perot tunable MOEMS filter array was combined with a miniature optics array and a focal plane array of 1024 x 1024 pixels to produce 16 colors every frame of the camera. Each color image has a spatial resolution of 256 x 256 pixels with an IFOV of 1.7 mrads and FOV of 25 degrees. The spectral images are collected simultaneously allowing high resolution spectral-spatial-temporal information in each frame of the camera, thus enabling the implementation of spectral-temporal-spatial algorithms in real-time to provide high sensitivity for the detection of weak signals in a high clutter background environment with low sensitivity to camera motion. The challenge in the design was the independent actuation of each Fabry Perot element in the array allowing for individual tuning. An additional challenge was the need to maximize the fill factor to improve the spatial coverage with minimal dead space. This paper will only address the concept design and analysis of the Fabry-Perot tunable filter array. A previous paper presented at SPIE DSS in 2012 explained the design of the optical array.

The coming paradigm shift: A transition from manual to automated microscopy.

PubMed

Farahani, Navid; Monteith, Corey E

2016-01-01

The field of pathology has used light microscopy (LM) extensively since the mid-19(th) century for examination of histological tissue preparations. This technology has remained the foremost tool in use by pathologists even as other fields have undergone a great change in recent years through new technologies. However, as new microscopy techniques are perfected and made available, this reliance on the standard LM will likely begin to change. Advanced imaging involving both diffraction-limited and subdiffraction techniques are bringing nondestructive, high-resolution, molecular-level imaging to pathology. Some of these technologies can produce three-dimensional (3D) datasets from sampled tissues. In addition, block-face/tissue-sectioning techniques are already providing automated, large-scale 3D datasets of whole specimens. These datasets allow pathologists to see an entire sample with all of its spatial information intact, and furthermore allow image analysis such as detection, segmentation, and classification, which are impossible in standard LM. It is likely that these technologies herald a major paradigm shift in the field of pathology.

Common hyperspectral image database design

NASA Astrophysics Data System (ADS)

Tian, Lixun; Liao, Ningfang; Chai, Ali

2009-11-01

This paper is to introduce Common hyperspectral image database with a demand-oriented Database design method (CHIDB), which comprehensively set ground-based spectra, standardized hyperspectral cube, spectral analysis together to meet some applications. The paper presents an integrated approach to retrieving spectral and spatial patterns from remotely sensed imagery using state-of-the-art data mining and advanced database technologies, some data mining ideas and functions were associated into CHIDB to make it more suitable to serve in agriculture, geological and environmental areas. A broad range of data from multiple regions of the electromagnetic spectrum is supported, including ultraviolet, visible, near-infrared, thermal infrared, and fluorescence. CHIDB is based on dotnet framework and designed by MVC architecture including five main functional modules: Data importer/exporter, Image/spectrum Viewer, Data Processor, Parameter Extractor, and On-line Analyzer. The original data were all stored in SQL server2008 for efficient search, query and update, and some advance Spectral image data Processing technology are used such as Parallel processing in C#; Finally an application case is presented in agricultural disease detecting area.

Advances on interdisciplinary approaches to urban carbon

NASA Astrophysics Data System (ADS)

Romero-Lankao, P.

2015-12-01

North American urban areas are emerging as climate policy and technology innovators, urbanization process laboratories, fonts of carbon relevant experiments, hubs for grass-roots mobilization, and centers for civil-society experiments to curb carbon emissions and avoid widespread and irreversible climate impacts. Since SOCCR diverse lines of inquiry on urbanization, urban areas and the carbon cycle have advanced our understanding of some of the societal processes through which energy and land uses affect carbon. This presentation provides an overview of these diverse perspectives. It suggests the need for approaches that complement and combine the plethora of existing insights into interdisciplinary explorations of how different urbanization processes, and socio-ecological and technological components of urban areas affect the spatial and temporal patterns of carbon emissions, differentially over time and within and across cities. It also calls for a more holistic approach to examining the carbon implications of urbanization and urban areas as places, based not only on demographics or income, but also on such other interconnected features of urban development pathways as urban form, economic function, economic growth policies and climate policies.

SPECT detectors: the Anger Camera and beyond

PubMed Central

Peterson, Todd E.; Furenlid, Lars R.

2011-01-01

The development of radiation detectors capable of delivering spatial information about gamma-ray interactions was one of the key enabling technologies for nuclear medicine imaging and, eventually, single-photon emission computed tomography (SPECT). The continuous NaI(Tl) scintillator crystal coupled to an array of photomultiplier tubes, almost universally referred to as the Anger Camera after its inventor, has long been the dominant SPECT detector system. Nevertheless, many alternative materials and configurations have been investigated over the years. Technological advances as well as the emerging importance of specialized applications, such as cardiac and preclinical imaging, have spurred innovation such that alternatives to the Anger Camera are now part of commercial imaging systems. Increased computing power has made it practical to apply advanced signal processing and estimation schemes to make better use of the information contained in the detector signals. In this review we discuss the key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic. PMID:21828904

Adult congenital heart disease imaging with second-generation dual-source computed tomography: initial experiences and findings.

PubMed

Ghoshhajra, Brian B; Sidhu, Manavjot S; El-Sherief, Ahmed; Rojas, Carlos; Yeh, Doreen Defaria; Engel, Leif-Christopher; Liberthson, Richard; Abbara, Suhny; Bhatt, Ami

2012-01-01

Adult congenital heart disease patients present a unique challenge to the cardiac imager. Patients may present with both acute and chronic manifestations of their complex congenital heart disease and also require surveillance for sequelae of their medical and surgical interventions. Multimodality imaging is often required to clarify their anatomy and physiology. Radiation dose is of particular concern in these patients with lifelong imaging needs for their chronic disease. The second-generation dual-source scanner is a recently available advanced clinical cardiac computed tomography (CT) scanner. It offers a combination of the high-spatial resolution of modern CT, the high-temporal resolution of dual-source technology, and the wide z-axis coverage of modern cone-beam geometry CT scanners. These advances in technology allow novel protocols that markedly reduce scan time, significantly reduce radiation exposure, and expand the physiologic imaging capabilities of cardiac CT. We present a case series of complicated adult congenital heart disease patients imaged by the second-generation dual-source CT scanner with extremely low-radiation doses and excellent image quality. © 2012 Wiley Periodicals, Inc.

Convergence Science in a Nano World

PubMed Central

Cady, Nathaniel

2013-01-01

Convergence is a new paradigm that brings together critical advances in the life sciences, physical sciences and engineering. Going beyond traditional “interdisciplinary” studies, “convergence” describes the culmination of truly integrated research and development, yielding revolutionary advances in both scientific research and new technologies. At its core, nanotechnology embodies these elements of convergence science by bringing together multiple disciplines with the goal of creating innovative and groundbreaking technologies. In the biological and biomedical sciences, nanotechnology research has resulted in dramatic improvements in sensors, diagnostics, imaging, and even therapeutics. In particular, there is a current push to examine the interface between the biological world and micro/nano-scale systems. For example, my laboratory is developing novel strategies for spatial patterning of biomolecules, electrical and optical biosensing, nanomaterial delivery systems, cellular patterning techniques, and the study of cellular interactions with nano-structured surfaces. In this seminar, I will give examples of how convergent research is being applied to three major areas of biological research &endash; cancer diagnostics, microbiology, and DNA-based biosensing. These topics will be presented as case studies, showing the benefits (and challenges) of multi-disciplinary, convergent research and development.

Design and implementation of spatial knowledge grid for integrated spatial analysis

NASA Astrophysics Data System (ADS)

Liu, Xiangnan; Guan, Li; Wang, Ping

2006-10-01

Supported by spatial information grid(SIG), the spatial knowledge grid (SKG) for integrated spatial analysis utilizes the middleware technology in constructing the spatial information grid computation environment and spatial information service system, develops spatial entity oriented spatial data organization technology, carries out the profound computation of the spatial structure and spatial process pattern on the basis of Grid GIS infrastructure, spatial data grid and spatial information grid (specialized definition). At the same time, it realizes the complex spatial pattern expression and the spatial function process simulation by taking the spatial intelligent agent as the core to establish space initiative computation. Moreover through the establishment of virtual geographical environment with man-machine interactivity and blending, complex spatial modeling, network cooperation work and spatial community decision knowledge driven are achieved. The framework of SKG is discussed systematically in this paper. Its implement flow and the key technology with examples of overlay analysis are proposed as well.

Using Geo-Spatial Technologies for Field Applications in Higher Geography Education

ERIC Educational Resources Information Center

Karatepe, Akif

2012-01-01

Today's important geo-spatial technologies, GIS (Geographic Information Systems), GPS (Global Positioning Systems) and Google Earth have been widely used in geography education. Transferring spatially oriented data taken by GPS to the GIS and Google Earth has provided great benefits in terms of showing the usage of spatial technologies for field…

Slumped glass optics for x-ray telescopes: advances in the hot slumping assisted by pressure

NASA Astrophysics Data System (ADS)

Salmaso, B.; Brizzolari, C.; Basso, S.; Civitani, M.; Ghigo, M.; Pareschi, G.; Spiga, D.; Tagliaferri, G.; Vecchi, G.

2015-09-01

Slumped Glass Optics is a viable solution to build future X-ray telescopes. In our laboratories we use a direct hot slumping approach assisted by pressure, in which the glass optical surface is in contact with the mould, and a pressure is applied to enforce the replication of the mould shape on the glass optical surface. Several prototypes have been already produced and tested in X-rays, showing a continuous improvement in our technology. In this paper, we present the advances in our technology, in terms of slumped glass foils quality and expected performances upon an ideal integration. By using Eagle XG glass foils and Zerodur K20 for the slumping mould, we have fine tuned several process parameters: we present a critical analysis correlating the changes in the process to the improvements in different spatial frequency ranges encompassing the profile and roughness measurements. The use of a re-polished K20 mould, together with the optimized process parameters, lead to the latest result of glass foils with expected performance of less than 3 arcsec in single reflection at 1 keV X-ray energy. This work presents all the relevant steps forward in the hot slumping technology assisted by pressure, aimed at reaching angular resolutions of 5 arcsec for the whole mirror assembly.

“Spatial Energetics”: Integrating Data From GPS, Accelerometry, and GIS to Address Obesity and Inactivity

PubMed Central

James, Peter; Jankowska, Marta; Marx, Christine; Hart, Jaime E.; Berrigan, David; Kerr, Jacqueline; Hurvitz, Philip M.; Hipp, J. Aaron; Laden, Francine

2016-01-01

To address the current obesity and inactivity epidemics, public health researchers have attempted to identify spatial factors that influence physical inactivity and obesity. Technologic and methodologic developments have led to a revolutionary ability to examine dynamic, high-resolution measures of temporally matched location and behavior data through GPS, accelerometry, and GIS. These advances allow the investigation of spatial energetics, high–spatiotemporal resolution data on location and time-matched energetics, to examine how environmental characteristics, space, and time are linked to activity-related health behaviors with far more robust and detailed data than in previous work. Although the transdisciplinary field of spatial energetics demonstrates promise to provide novel insights on how individuals and populations interact with their environment, there remain significant conceptual, technical, analytical, and ethical challenges stemming from the complex data streams that spatial energetics research generates. First, it is essential to better understand what spatial energetics data represent, the relevant spatial context of analysis for these data, and if spatial energetics can establish causality for development of spatially relevant interventions. Second, there are significant technical problems for analysis of voluminous and complex data that may require development of spatially aware scalable computational infrastructures. Third, the field must come to agreement on appropriate statistical methodologies to account for multiple observations per person. Finally, these challenges must be considered within the context of maintaining participant privacy and security. This article describes gaps in current practice and understanding, and suggests solutions to move this promising area of research forward. PMID:27528538

Study on analysis from sources of error for Airborne LIDAR

NASA Astrophysics Data System (ADS)

Ren, H. C.; Yan, Q.; Liu, Z. J.; Zuo, Z. Q.; Xu, Q. Q.; Li, F. F.; Song, C.

2016-11-01

With the advancement of Aerial Photogrammetry, it appears that to obtain geo-spatial information of high spatial and temporal resolution provides a new technical means for Airborne LIDAR measurement techniques, with unique advantages and broad application prospects. Airborne LIDAR is increasingly becoming a new kind of space for earth observation technology, which is mounted by launching platform for aviation, accepting laser pulses to get high-precision, high-density three-dimensional coordinate point cloud data and intensity information. In this paper, we briefly demonstrates Airborne laser radar systems, and that some errors about Airborne LIDAR data sources are analyzed in detail, so the corresponding methods is put forwarded to avoid or eliminate it. Taking into account the practical application of engineering, some recommendations were developed for these designs, which has crucial theoretical and practical significance in Airborne LIDAR data processing fields.

Temporal and spatial regulation of mRNA export: Single particle RNA-imaging provides new tools and insights

PubMed Central

Heinrich, Stephanie; Derrer, Carina Patrizia; Lari, Azra; Weis, Karsten; Montpetit, Ben

2017-01-01

The transport of messenger RNAs (mRNAs) from the nucleus to cytoplasm is an essential step in the gene expression program of all eukaryotes. Recent technological advances in the areas of RNA-labeling, microscopy, and sequencing are leading to novel insights about mRNA biogenesis and export. This includes quantitative single molecule imaging (SMI) of RNA molecules in live cells, which is providing knowledge of the spatial and temporal dynamics of the export process. As this information becomes available, it leads to new questions, the reinterpretation of previous findings, and revised models of mRNA export. In this review, we will briefly highlight some of these recent findings and discuss how live cell SMI approaches may be used to further our current understanding of mRNA export and gene expression. PMID:28052353

Utilization of volume correlation filters for underwater mine identification in LIDAR imagery

NASA Astrophysics Data System (ADS)

Walls, Bradley

2008-04-01

Underwater mine identification persists as a critical technology pursued aggressively by the Navy for fleet protection. As such, new and improved techniques must continue to be developed in order to provide measurable increases in mine identification performance and noticeable reductions in false alarm rates. In this paper we show how recent advances in the Volume Correlation Filter (VCF) developed for ground based LIDAR systems can be adapted to identify targets in underwater LIDAR imagery. Current automated target recognition (ATR) algorithms for underwater mine identification employ spatial based three-dimensional (3D) shape fitting of models to LIDAR data to identify common mine shapes consisting of the box, cylinder, hemisphere, truncated cone, wedge, and annulus. VCFs provide a promising alternative to these spatial techniques by correlating 3D models against the 3D rendered LIDAR data.

Advanced Image Processing for NASA Applications

NASA Technical Reports Server (NTRS)

LeMoign, Jacqueline

2007-01-01

The future of space exploration will involve cooperating fleets of spacecraft or sensor webs geared towards coordinated and optimal observation of Earth Science phenomena. The main advantage of such systems is to utilize multiple viewing angles as well as multiple spatial and spectral resolutions of sensors carried on multiple spacecraft but acting collaboratively as a single system. Within this framework, our research focuses on all areas related to sensing in collaborative environments, which means systems utilizing intracommunicating spatially distributed sensor pods or crafts being deployed to monitor or explore different environments. This talk will describe the general concept of sensing in collaborative environments, will give a brief overview of several technologies developed at NASA Goddard Space Flight Center in this area, and then will concentrate on specific image processing research related to that domain, specifically image registration and image fusion.

Remote sensing of landscape-level coastal environmental indicators.

PubMed

Klemas, V V

2001-01-01

Advances in technology and decreases in cost are making remote sensing (RS) and geographic information systems (GIS) practical and attractive for use in coastal resource management. They are also allowing researchers and managers to take a broader view of ecological patterns and processes. Landscape-level environmental indicators that can be detected by Landsat Thematic Mapper (TM) and other remote sensors are available to provide quantitative estimates of coastal and estuarine habitat conditions and trends. Such indicators include watershed land cover, riparian buffers, shoreline and wetland changes, among others. With the launch of Landsat 7, the cost of TM imagery has dropped by nearly a factor of 10, decreasing the cost of monitoring large coastal areas and estuaries. New satellites, carrying sensors with much finer spatial (1-5 m) and spectral (200 narrow bands) resolutions are being launched, providing a capability to more accurately detect changes in coastal habitat and wetland health. Advances in the application of GIS help incorporate ancillary data layers to improve the accuracy of satellite land-cover classification. When these techniques for generating, organizing, storing, and analyzing spatial information are combined with mathematical models, coastal planners and managers have a means for assessing the impacts of alternative management practices.

E-Learning in Photogrammetry, Remote Sensing and Spatial Information Science

NASA Astrophysics Data System (ADS)

Vyas, Anjana; König, Gerhard

2016-06-01

Science and technology are evolving leaps and bounds. The advancements in GI-Science for natural and built environment helps in improving the quality of life. Learning through education and training needs to be at par with those advancements, which plays a vital role in utilization of technology. New technologies that creates new opportunities have enabled Geomatics to broaden the horizon (skills and competencies). Government policies and decisions support the use of geospatial science in various sectors of governance. Mapping, Land management, Urban planning, Environmental planning, Industrialization are some of the areas where the geomatics has become a baseline for decision making at national level. There is a need to bridge the gap between developments in geospatial science and its utilization and implementation. To prepare a framework for standardisation it is important to understand the theories of education and prevailing practices, with articulate goals exploring variety of teaching techniques. E-Learning is an erudition practice shaped for facilitating learning and improving performance by creating, using and managing appropriate technological processes and resources through digital and network-enabled technology. It is a shift from traditional education or training to ICT-based flexible and collaborative learning based on the community of learners, academia, professionals, experts and facilitators. Developments in e-learning is focussed on computer assisted learning which has become popular because of its potential for providing more flexible access to content and instruction at any time, from any place (Means et al, 2009). With the advent of the geo-spatial technology, fast development in the software and hardware, the demand for skilled manpower is increasing and the need is for training, education, research and dissemination. It suggests inter-organisational cooperation between academia, industry, government and international collaboration. There is a nascent need to adopt multi-specialisation approach to examine the issues and challenges of research in such a valued topic of education and training in multi-disciplinary areas. Learning involve a change in an individual's knowledge, ability to perform a skill, participate and communicate. There is considerable variation among the theories about the nature of this change. This paper derives from a scientific research grant received from ISPRS, reveals a summary result from assessing various theories and methods of evaluation of learning through education, system and structure of it for GeoInformatics.

Advances in Gamma-Ray Imaging with Intensified Quantum-Imaging Detectors

NASA Astrophysics Data System (ADS)

Han, Ling

Nuclear medicine, an important branch of modern medical imaging, is an essential tool for both diagnosis and treatment of disease. As the fundamental element of nuclear medicine imaging, the gamma camera is able to detect gamma-ray photons emitted by radiotracers injected into a patient and form an image of the radiotracer distribution, reflecting biological functions of organs or tissues. Recently, an intensified CCD/CMOS-based quantum detector, called iQID, was developed in the Center for Gamma-Ray Imaging. Originally designed as a novel type of gamma camera, iQID demonstrated ultra-high spatial resolution (< 100 micron) and many other advantages over traditional gamma cameras. This work focuses on advancing this conceptually-proven gamma-ray imaging technology to make it ready for both preclinical and clinical applications. To start with, a Monte Carlo simulation of the key light-intensification device, i.e. the image intensifier, was developed, which revealed the dominating factor(s) that limit energy resolution performance of the iQID cameras. For preclinical imaging applications, a previously-developed iQID-based single-photon-emission computed-tomography (SPECT) system, called FastSPECT III, was fully advanced in terms of data acquisition software, system sensitivity and effective FOV by developing and adopting a new photon-counting algorithm, thicker columnar scintillation detectors, and system calibration method. Originally designed for mouse brain imaging, the system is now able to provide full-body mouse imaging with sub-350-micron spatial resolution. To further advance the iQID technology to include clinical imaging applications, a novel large-area iQID gamma camera, called LA-iQID, was developed from concept to prototype. Sub-mm system resolution in an effective FOV of 188 mm x 188 mm has been achieved. The camera architecture, system components, design and integration, data acquisition, camera calibration, and performance evaluation are presented in this work. Mounted on a castered counter-weighted clinical cart, the camera also features portable and mobile capabilities for easy handling and on-site applications at remote locations where hospital facilities are not available.

The lartge-area picosecond photo-detector (LAPPD) project

NASA Astrophysics Data System (ADS)

Varner, Gary

2012-03-01

The technological revolution that replaced the bulky Cathode Ray Tube with a wide variety of thin, reduced-cost display technologies, has yet to be realized for photosensors. Such a low-cost, robust and flexible photon detector, capable of efficient single photon measurement with good spatial and temporal resolution, would have numerous scientific, medical and industrial applications. To address the significant technological challenges of realizing such a disruptive technology, the Large Area Picosecond Photo-Detector (LAPPD) collaboration was formed, and has been strongly supported by the Department of Energy. This group leverages the inter-disciplinary capabilities and facilities at Argonne National Laboratory, the Berkeley Space Sciences Laboratory (SSL), electronics expertise at the Universities of Chicago and Hawaii, and close work with industrial partners to extend the known technologies. Advances in theory-inspired design and in-situ photocathode characterization during growth, Atomic Layer Deposition (ALD) for revolutionizing micro-channel plate fabrication, and compact, wave-form sampling CMOS ASIC readout of micro striplines are key tools toward realizing a viable LAPPD device. Progress toward a first 8" x 8" demonstrator module will be presented.

Increased genomic prediction accuracy in wheat breeding through spatial adjustment of field trial data.

PubMed

Lado, Bettina; Matus, Ivan; Rodríguez, Alejandra; Inostroza, Luis; Poland, Jesse; Belzile, François; del Pozo, Alejandro; Quincke, Martín; Castro, Marina; von Zitzewitz, Jarislav

2013-12-09

In crop breeding, the interest of predicting the performance of candidate cultivars in the field has increased due to recent advances in molecular breeding technologies. However, the complexity of the wheat genome presents some challenges for applying new technologies in molecular marker identification with next-generation sequencing. We applied genotyping-by-sequencing, a recently developed method to identify single-nucleotide polymorphisms, in the genomes of 384 wheat (Triticum aestivum) genotypes that were field tested under three different water regimes in Mediterranean climatic conditions: rain-fed only, mild water stress, and fully irrigated. We identified 102,324 single-nucleotide polymorphisms in these genotypes, and the phenotypic data were used to train and test genomic selection models intended to predict yield, thousand-kernel weight, number of kernels per spike, and heading date. Phenotypic data showed marked spatial variation. Therefore, different models were tested to correct the trends observed in the field. A mixed-model using moving-means as a covariate was found to best fit the data. When we applied the genomic selection models, the accuracy of predicted traits increased with spatial adjustment. Multiple genomic selection models were tested, and a Gaussian kernel model was determined to give the highest accuracy. The best predictions between environments were obtained when data from different years were used to train the model. Our results confirm that genotyping-by-sequencing is an effective tool to obtain genome-wide information for crops with complex genomes, that these data are efficient for predicting traits, and that correction of spatial variation is a crucial ingredient to increase prediction accuracy in genomic selection models.

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

Quantifying seascape structure: Extending terrestrial spatial pattern metrics to the marine realm

USGS Publications Warehouse

Wedding, L.M.; Christopher, L.A.; Pittman, S.J.; Friedlander, A.M.; Jorgensen, S.

2011-01-01

Spatial pattern metrics have routinely been applied to characterize and quantify structural features of terrestrial landscapes and have demonstrated great utility in landscape ecology and conservation planning. The important role of spatial structure in ecology and management is now commonly recognized, and recent advances in marine remote sensing technology have facilitated the application of spatial pattern metrics to the marine environment. However, it is not yet clear whether concepts, metrics, and statistical techniques developed for terrestrial ecosystems are relevant for marine species and seascapes. To address this gap in our knowledge, we reviewed, synthesized, and evaluated the utility and application of spatial pattern metrics in the marine science literature over the past 30 yr (1980 to 2010). In total, 23 studies characterized seascape structure, of which 17 quantified spatial patterns using a 2-dimensional patch-mosaic model and 5 used a continuously varying 3-dimensional surface model. Most seascape studies followed terrestrial-based studies in their search for ecological patterns and applied or modified existing metrics. Only 1 truly unique metric was found (hydrodynamic aperture applied to Pacific atolls). While there are still relatively few studies using spatial pattern metrics in the marine environment, they have suffered from similar misuse as reported for terrestrial studies, such as the lack of a priori considerations or the problem of collinearity between metrics. Spatial pattern metrics offer great potential for ecological research and environmental management in marine systems, and future studies should focus on (1) the dynamic boundary between the land and sea; (2) quantifying 3-dimensional spatial patterns; and (3) assessing and monitoring seascape change. ?? Inter-Research 2011.

Preparatory neural activity predicts performance on a conflict task.

PubMed

Stern, Emily R; Wager, Tor D; Egner, Tobias; Hirsch, Joy; Mangels, Jennifer A

2007-10-24

Advance preparation has been shown to improve the efficiency of conflict resolution. Yet, with little empirical work directly linking preparatory neural activity to the performance benefits of advance cueing, it is not clear whether this relationship results from preparatory activation of task-specific networks, or from activity associated with general alerting processes. Here, fMRI data were acquired during a spatial Stroop task in which advance cues either informed subjects of the upcoming relevant feature of conflict stimuli (spatial or semantic) or were neutral. Informative cues decreased reaction time (RT) relative to neutral cues, and cues indicating that spatial information would be task-relevant elicited greater activity than neutral cues in multiple areas, including right anterior prefrontal and bilateral parietal cortex. Additionally, preparatory activation in bilateral parietal cortex and right dorsolateral prefrontal cortex predicted faster RT when subjects responded to spatial location. No regions were found to be specific to semantic cues at conventional thresholds, and lowering the threshold further revealed little overlap between activity associated with spatial and semantic cueing effects, thereby demonstrating a single dissociation between activations related to preparing a spatial versus semantic task-set. This relationship between preparatory activation of spatial processing networks and efficient conflict resolution suggests that advance information can benefit performance by leading to domain-specific biasing of task-relevant information.

Spatial services grid

NASA Astrophysics Data System (ADS)

Cao, Jian; Li, Qi; Cheng, Jicheng

2005-10-01

This paper discusses the concept, key technologies and main application of Spatial Services Grid. The technologies of Grid computing and Webservice is playing a revolutionary role in studying the spatial information services. The concept of the SSG (Spatial Services Grid) is put forward based on the SIG (Spatial Information Grid) and OGSA (open grid service architecture). Firstly, the grid computing is reviewed and the key technologies of SIG and their main applications are reviewed. Secondly, the grid computing and three kinds of SIG (in broad sense)--SDG (spatial data grid), SIG (spatial information grid) and SSG (spatial services grid) and their relationships are proposed. Thirdly, the key technologies of the SSG (spatial services grid) is put forward. Finally, three representative applications of SSG (spatial services grid) are discussed. The first application is urban location based services gird, which is a typical spatial services grid and can be constructed on OGSA (Open Grid Services Architecture) and digital city platform. The second application is region sustainable development grid which is the key to the urban development. The third application is Region disaster and emergency management services grid.

Gold nanoparticle contrast agents in advanced X-ray imaging technologies.

PubMed

Ahn, Sungsook; Jung, Sung Yong; Lee, Sang Joon

2013-05-17

Recently, there has been significant progress in the field of soft- and hard-X-ray imaging for a wide range of applications, both technically and scientifically, via developments in sources, optics and imaging methodologies. While one community is pursuing extensive applications of available X-ray tools, others are investigating improvements in techniques, including new optics, higher spatial resolutions and brighter compact sources. For increased image quality and more exquisite investigation on characteristic biological phenomena, contrast agents have been employed extensively in imaging technologies. Heavy metal nanoparticles are excellent absorbers of X-rays and can offer excellent improvements in medical diagnosis and X-ray imaging. In this context, the role of gold (Au) is important for advanced X-ray imaging applications. Au has a long-history in a wide range of medical applications and exhibits characteristic interactions with X-rays. Therefore, Au can offer a particular advantage as a tracer and a contrast enhancer in X-ray imaging technologies by sensing the variation in X-ray attenuation in a given sample volume. This review summarizes basic understanding on X-ray imaging from device set-up to technologies. Then this review covers recent studies in the development of X-ray imaging techniques utilizing gold nanoparticles (AuNPs) and their relevant applications, including two- and three-dimensional biological imaging, dynamical processes in a living system, single cell-based imaging and quantitative analysis of circulatory systems and so on. In addition to conventional medical applications, various novel research areas have been developed and are expected to be further developed through AuNP-based X-ray imaging technologies.

Spatial Competition: Roughening of an Experimental Interface.

PubMed

Allstadt, Andrew J; Newman, Jonathan A; Walter, Jonathan A; Korniss, G; Caraco, Thomas

2016-07-28

Limited dispersal distance generates spatial aggregation. Intraspecific interactions are then concentrated within clusters, and between-species interactions occur near cluster boundaries. Spread of a locally dispersing invader can become motion of an interface between the invading and resident species, and spatial competition will produce variation in the extent of invasive advance along the interface. Kinetic roughening theory offers a framework for quantifying the development of these fluctuations, which may structure the interface as a self-affine fractal, and so induce a series of temporal and spatial scaling relationships. For most clonal plants, advance should become spatially correlated along the interface, and width of the interface (where invader and resident compete directly) should increase as a power function of time. Once roughening equilibrates, interface width and the relative location of the most advanced invader should each scale with interface length. We tested these predictions by letting white clover (Trifolium repens) invade ryegrass (Lolium perenne). The spatial correlation of clover growth developed as anticipated by kinetic roughening theory, and both interface width and the most advanced invader's lead scaled with front length. However, the scaling exponents differed from those predicted by recent simulation studies, likely due to clover's growth morphology.

Spatial Competition: Roughening of an Experimental Interface

PubMed Central

Allstadt, Andrew J.; Newman, Jonathan A.; Walter, Jonathan A.; Korniss, G.; Caraco, Thomas

2016-01-01

Limited dispersal distance generates spatial aggregation. Intraspecific interactions are then concentrated within clusters, and between-species interactions occur near cluster boundaries. Spread of a locally dispersing invader can become motion of an interface between the invading and resident species, and spatial competition will produce variation in the extent of invasive advance along the interface. Kinetic roughening theory offers a framework for quantifying the development of these fluctuations, which may structure the interface as a self-affine fractal, and so induce a series of temporal and spatial scaling relationships. For most clonal plants, advance should become spatially correlated along the interface, and width of the interface (where invader and resident compete directly) should increase as a power function of time. Once roughening equilibrates, interface width and the relative location of the most advanced invader should each scale with interface length. We tested these predictions by letting white clover (Trifolium repens) invade ryegrass (Lolium perenne). The spatial correlation of clover growth developed as anticipated by kinetic roughening theory, and both interface width and the most advanced invader’s lead scaled with front length. However, the scaling exponents differed from those predicted by recent simulation studies, likely due to clover’s growth morphology. PMID:27465518

Impairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms.

PubMed

Wu, Tianshu; He, Keyu; Ang, Shengjun; Ying, Jiali; Zhang, Shihan; Zhang, Ting; Xue, Yuying; Tang, Meng

2016-01-01

With the rapid development of nanotechnology, quantum dots (QDs) as advanced nanotechnology products have been widely used in neuroscience, including basic neurological studies and diagnosis or therapy for neurological disorders, due to their superior optical properties. In recent years, there has been intense concern regarding the toxicity of QDs, with a growing number of studies. However, knowledge of neurotoxic consequences of QDs applied in living organisms is lagging behind their development, even if several studies have attempted to evaluate the toxicity of QDs on neural cells. The aim of this study was to evaluate the adverse effects of intrahippocampal injection in rats of 3-mercaptopropionic acid (MPA)-modified CdTe QDs and underlying mechanisms. First of all, we observed impairments in learning efficiency and spatial memory in the MPA-modified CdTe QD-treated rats by using open-field and Y-maze tests, which could be attributed to pathological changes and disruption of ultrastructure of neurons and synapses in the hippocampus. In order to find the mechanisms causing these effects, transcriptome sequencing (RNA-seq), an advanced technology, was used to gain the potentially molecular targets of MPA-modified CdTe QDs. According to ample data from RNA-seq, we chose the signaling pathways of PI3K-Akt and MPAK-ERK to do a thorough investigation, because they play important roles in synaptic plasticity, long-term potentiation, and spatial memory. The data demonstrated that phosphorylated Akt (p-Akt), p-ERK1/2, and c-FOS signal transductions in the hippocampus of rats were involved in the mechanism underlying spatial learning and memory impairments caused by 3.5 nm MPA-modified CdTe QDs.

Swiss Experiment: Design, implemention and use of a cross-disciplinary infrastructure for data intensive science

NASA Astrophysics Data System (ADS)

Dawes, N.; Salehi, A.; Clifton, A.; Bavay, M.; Aberer, K.; Parlange, M. B.; Lehning, M.

2010-12-01

It has long been known that environmental processes are cross-disciplinary, but data has continued to be acquired and held for a single purpose. Swiss Experiment is a rapidly evolving cross-disciplinary, distributed sensor data infrastructure, where tools for the environmental science community stem directly from computer science research. The platform uses the bleeding edge of computer science to acquire, store and distribute data and metadata from all environmental science disciplines at a variety of temporal and spatial resolutions. SwissEx is simultaneously developing new technologies to allow low cost, high spatial and temporal resolution measurements such that small areas can be intensely monitored. This data is then combined with existing widespread, low density measurements in the cross-disciplinary platform to provide well documented datasets, which are of use to multiple research disciplines. We present a flexible, generic infrastructure at an advanced stage of development. The infrastructure makes the most of Web 2.0 technologies for a collaborative working environment and as a user interface for a metadata database. This environment is already closely integrated with GSN, an open-source database middleware developed under Swiss Experiment for acquisition and storage of generic time-series data (2D and 3D). GSN can be queried directly by common data processing packages and makes data available in real-time to models and 3rd party software interfaces via its web service interface. It also provides real-time push or pull data exchange between instances, a user management system which leaves data owners in charge of their data, advanced real-time processing and much more. The SwissEx interface is increasingly gaining users and supporting environmental science in Switzerland. It is also an integral part of environmental education projects ClimAtscope and O3E, where the technologies can provide rapid feedback of results for children of all ages and where the data from their own stations can be compared to national data networks.

Applications of Microscale Technologies for Regenerative Dentistry

PubMed Central

Hacking, S.A.; Khademhosseini, A.

2009-01-01

While widespread advances in tissue engineering have occurred over the past decade, many challenges remain in the context of tissue engineering and regeneration of the tooth. For example, although tooth development is the result of repeated temporal and spatial interactions between cells of ectoderm and mesoderm origin, most current tooth engineering systems cannot recreate such developmental processes. In this regard, microscale approaches that spatially pattern and support the development of different cell types in close proximity can be used to regulate the cellular microenvironment and, as such, are promising approaches for tooth development. Microscale technologies also present alternatives to conventional tissue engineering approaches in terms of scaffolds and the ability to direct stem cells. Furthermore, microscale techniques can be used to miniaturize many in vitro techniques and to facilitate high-throughput experimentation. In this review, we discuss the emerging microscale technologies for the in vitro evaluation of dental cells, dental tissue engineering, and tooth regeneration. Abbreviations: AS, adult stem cell; BMP, bone morphogenic protein; ECM, extracellular matrix; ES, embryonic stem cell; HA, hydroxyapatite; FGF-2, fibroblast growth factor; iPS, inducible pleuripotent stem cell; IGF-1, insulin-like growth factor; PDGF, platelet-derived growth factor; PDMS, poly(dimethylsiloxane); PGA, polyglycolate; PGS, polyglycerol sebacate; PLGA, poly-L-lactate-co-glycolate; PLL, poly-L-lactate; RGD, Arg-Gly-Asp attachment site; TCP, tricalcium phosphate; TGF-β, transforming growth factor beta; and VEGF, vascular endothelial growth factor. PMID:19493883

Community Needs Assessment and Portal Prototype Development for an Arctic Spatial Data Infrastructure (ASDI): A Contribution to an IPY Data Cyberinfrastructure

NASA Astrophysics Data System (ADS)

Wiggins, H. V.; Warnick, W. K.; Hempel, L. C.; Henk, J.; Sorensen, M.; Tweedie, C. E.; Gaylord, A.; Behr, S.

2006-12-01

As the creation and use of geospatial data in research, management, logistics, and education applications has proliferated, there is now a tremendous potential for advancing the IPY initiative through a variety of cyberinfrastructure applications, including Spatial Data Infrastructure (SDI) and related technologies. SDIs provide a necessary and common framework of standards, securities, policies, procedures, and technology to support the effective acquisition, coordination, dissemination and use of geospatial data by multiple and distributed stakeholder and user groups. Despite the numerous research activities in the Arctic, there is no established SDI and, because of this lack of a coordinated infrastructure, there is inefficiency, duplication of effort, and reduced data quality and search ability of arctic geospatial data. The urgency for establishing this framework is significant considering the myriad of data that is likely to be collected in celebration of the International Polar Year (IPY) in 2007-2008 and the current international momentum for an improved and integrated circumarctic terrestrial-marine-atmospheric environmental observatories network. The key objective of this project is to lay the foundation for full implementation of an Arctic Spatial Data Infrastructure (ASDI) through two related activities: (1) an assessment - via interviews, questionnaires, a workshop, and other means - of community needs, readiness, and resources, and (2) the development of a prototype web mapping portal to demonstrate the purpose and function on an arctic geospatial one-stop portal technology and to solicit community input on design and function. The results of this project will be compiled into a comprehensive report guiding the research community and funding agencies in the design and implementation of an ASDI to contribute to a robust IPY data cyberinfrastructure.

D Data Acquisition Based on Opencv for Close-Range Photogrammetry Applications

NASA Astrophysics Data System (ADS)

Jurjević, L.; Gašparović, M.

2017-05-01

Development of the technology in the area of the cameras, computers and algorithms for 3D the reconstruction of the objects from the images resulted in the increased popularity of the photogrammetry. Algorithms for the 3D model reconstruction are so advanced that almost anyone can make a 3D model of photographed object. The main goal of this paper is to examine the possibility of obtaining 3D data for the purposes of the close-range photogrammetry applications, based on the open source technologies. All steps of obtaining 3D point cloud are covered in this paper. Special attention is given to the camera calibration, for which two-step process of calibration is used. Both, presented algorithm and accuracy of the point cloud are tested by calculating the spatial difference between referent and produced point clouds. During algorithm testing, robustness and swiftness of obtaining 3D data is noted, and certainly usage of this and similar algorithms has a lot of potential in the real-time application. That is the reason why this research can find its application in the architecture, spatial planning, protection of cultural heritage, forensic, mechanical engineering, traffic management, medicine and other sciences.

Public road infrastructure inventory in degraded global navigation satellite system signal environments

NASA Astrophysics Data System (ADS)

Sokolova, N.; Morrison, A.; Haakonsen, T. A.

2015-04-01

Recent advancement of land-based mobile mapping enables rapid and cost-effective collection of highquality road related spatial information. Mobile Mapping Systems (MMS) can provide spatial information with subdecimeter accuracy in nominal operation environments. However, performance in challenging environments such as tunnels is not well characterized. The Norwegian Public Roads Administration (NPRA) manages the country's public road network and its infrastructure, a large segment of which is represented by road tunnels (there are about 1 000 road tunnels in Norway with a combined length of 800 km). In order to adopt mobile mapping technology for streamlining road network and infrastructure management and maintenance tasks, it is important to ensure that the technology is mature enough to meet existing requirements for object positioning accuracy in all types of environments, and provide homogeneous accuracy over the mapping perimeter. This paper presents results of a testing campaign performed within a project funded by the NPRA as a part of SMarter road traffic with Intelligent Transport Systems (ITS) (SMITS) program. The testing campaign objective was performance evaluation of high end commercial MMSs for inventory of public areas, focusing on Global Navigation Satellite System (GNSS) signal degraded environments.

Ubiquitous geospatial concept in evolution of the macro and micro spatial planning

NASA Astrophysics Data System (ADS)

Sabri, S.; Ludin, A. N. M.; Majid, M. R.

2014-02-01

There are many examples of GIS application in planning such as urban land-use planning, cultural heritage conservation, coastal zone management, and the design of structure plans for sustainable economic development. All these applications are dealing with systems in which natural and human factors are interconnected. But an issue that should be addressed is to what extent the current information technology is able to connect all these parts together? Contemporary improvement in information technology made the computer so imbedded in our everyday practices that we use it without having to think about it. Thus, computing is becoming truly ubiquitous and is available anywhere anytime. Advances in the internet facilities and devices, such as high speed wireless networks, mobile middleware, and smart technologies, has pushed the concept of ubiquitous computing to the forefront of GIS research and development. There are developments in this regards, these are such as GeoWeb 2.0, voluntarily geographic Information (VGI), and Mashups, whereby the application of cloud computing was possible in visualizing urban air pollution and emergency responses to ensure the safety and security. These advancements therefore, have changed the conventional facet of macro and micro spatial planning. Every possible information system such as residential, medical, business, environmental, governmental, and the like can be linked through ubiquitous computing technologies and acts as a virtually one system which works for society. However, the journey to achieve a true ubiquitous GIS is not without challenges. Despite the current potentials there are many issues and obstacles need to be addressed before GIS can to be truly ubiquitous in planning context. Perhaps four criteria as explained by Goodchild et al (1997) can be applied to ubiquitous GIS in planning very well: the system must be distributed (data storage, processing and user interaction can occur at locations that are potentially widely scattered), disaggregated (the monolithic systems are replaced by 'plug and play' components designed to interoperate through conformance with industry-wide standards), decoupled (system must be able to access a number of components over many networks required to complete a specific task) and, interoperable (system is based on an "open" system).

Stimulating Innovation and Accelerating the Development of Complex and Slowly Maturing Technologies Through Advanced Technology Prize Competitions

DTIC Science & Technology

2007-06-15

technology prize competitions have been used since the 18th century to spur innovation and advance the development of complex and slowly maturing disruptive ... technologies The Defense Advanced Research Projects Agency (DARPA) has used advanced technology competitions in 2004 and 2005 to rapidly accelerate the

Multispectral Filter Arrays: Recent Advances and Practical Implementation

PubMed Central

Lapray, Pierre-Jean; Wang, Xingbo; Thomas, Jean-Baptiste; Gouton, Pierre

2014-01-01

Thanks to some technical progress in interferencefilter design based on different technologies, we can finally successfully implement the concept of multispectral filter array-based sensors. This article provides the relevant state-of-the-art for multispectral imaging systems and presents the characteristics of the elements of our multispectral sensor as a case study. The spectral characteristics are based on two different spatial arrangements that distribute eight different bandpass filters in the visible and near-infrared area of the spectrum. We demonstrate that the system is viable and evaluate its performance through sensor spectral simulation. PMID:25407904

Techniques for animation of CFD results. [computational fluid dynamics

NASA Technical Reports Server (NTRS)

Horowitz, Jay; Hanson, Jeffery C.

1992-01-01

Video animation is becoming increasingly vital to the computational fluid dynamics researcher, not just for presentation, but for recording and comparing dynamic visualizations that are beyond the current capabilities of even the most powerful graphic workstation. To meet these needs, Lewis Research Center has recently established a facility to provide users with easy access to advanced video animation capabilities. However, producing animation that is both visually effective and scientifically accurate involves various technological and aesthetic considerations that must be understood both by the researcher and those supporting the visualization process. These considerations include: scan conversion, color conversion, and spatial ambiguities.

The Dynamics of the Atmospheric Radiation Environment at Aviation Altitudes

NASA Technical Reports Server (NTRS)

Stassinopoulos, Epaminondas G.

2004-01-01

Single Event Effects vulnerability of on-board computers that regulate the: navigational, flight control, communication, and life support systems has become an issue in advanced modern aircraft, especially those that may be equipped with new technology devices in terabit memory banks (low voltage, nanometer feature size, gigabit integration). To address this concern, radiation spectrometers need to fly continually on a multitude of carriers over long periods of time so as to accumulate sufficient information that will broaden our understanding of the very dynamic and complex nature of the atmospheric radiation environment regarding: composition, spectral distribution, intensity, temporal variation, and spatial variation.

Research on key technologies for data-interoperability-based metadata, data compression and encryption, and their application

NASA Astrophysics Data System (ADS)

Yu, Xu; Shao, Quanqin; Zhu, Yunhai; Deng, Yuejin; Yang, Haijun

2006-10-01

With the development of informationization and the separation between data management departments and application departments, spatial data sharing becomes one of the most important objectives for the spatial information infrastructure construction, and spatial metadata management system, data transmission security and data compression are the key technologies to realize spatial data sharing. This paper discusses the key technologies for metadata based on data interoperability, deeply researches the data compression algorithms such as adaptive Huffman algorithm, LZ77 and LZ78 algorithm, studies to apply digital signature technique to encrypt spatial data, which can not only identify the transmitter of spatial data, but also find timely whether the spatial data are sophisticated during the course of network transmission, and based on the analysis of symmetric encryption algorithms including 3DES,AES and asymmetric encryption algorithm - RAS, combining with HASH algorithm, presents a improved mix encryption method for spatial data. Digital signature technology and digital watermarking technology are also discussed. Then, a new solution of spatial data network distribution is put forward, which adopts three-layer architecture. Based on the framework, we give a spatial data network distribution system, which is efficient and safe, and also prove the feasibility and validity of the proposed solution.

Monitoring protocols: Options, approaches, implementation, benefits

USGS Publications Warehouse

Karl, Jason W.; Herrick, Jeffrey E.; Pyke, David A.

2017-01-01

Monitoring and adaptive management are fundamental concepts to rangeland management across land management agencies and embodied as best management practices for private landowners. Historically, rangeland monitoring was limited to determining impacts or maximizing the potential of specific land uses—typically grazing. Over the past several decades, though, the uses of and disturbances to rangelands have increased dramatically against a backdrop of global climate change that adds uncertainty to predictions of future rangeland conditions. Thus, today’s monitoring needs are more complex (or multidimensional) and yet still must be reconciled with the realities of costs to collect requisite data. However, conceptual advances in rangeland ecology and management and changes in natural resource policies and societal values over the past 25 years have facilitated new approaches to monitoring that can support rangeland management’s diverse information needs. Additionally, advances in sensor technologies and remote-sensing techniques have broadened the suite of rangeland attributes that can be monitored and the temporal and spatial scales at which they can be monitored. We review some of the conceptual and technological advancements and provide examples of how they have influenced rangeland monitoring. We then discuss implications of these developments for rangeland management and highlight what we see as challenges and opportunities for implementing effective rangeland monitoring. We conclude with a vision for how monitoring can contribute to rangeland information needs in the future.

SMAP Soil Moisture Disaggregation using Land Surface Temperature and Vegetation Data

NASA Astrophysics Data System (ADS)

Fang, B.; Lakshmi, V.

2016-12-01

Soil moisture (SM) is a key parameter in agriculture, hydrology and ecology studies. The global SM retrievals have been providing by microwave remote sensing technology since late 1970s and many SM retrieval algorithms have been developed, calibrated and applied on satellite sensors such as AMSR-E (Advanced Microwave Scanning Radiometer for the Earth Observing System), AMSR-2 (Advanced Microwave Scanning Radiometer 2) and SMOS (Soil Moisture and Ocean Salinity). Particularly, SMAP (Soil Moisture Active/Passive) satellite, which was developed by NASA, was launched in January 2015. SMAP provides soil moisture products of 9 km and 36 km spatial resolutions which are not capable for research and applications of finer scale. Toward this issue, this study applied a SM disaggregation algorithm to disaggregate SMAP passive microwave soil moisture 36 km product. This algorithm was developed based on the thermal inertial relationship between daily surface temperature variation and daily average soil moisture which is modulated by vegetation condition, by using remote sensing retrievals from AVHRR (Advanced Very High Resolution Radiometer, MODIS (Moderate Resolution Imaging Spectroradiometer), SPOT (Satellite Pour l'Observation de la Terre), as well as Land Surface Model (LSM) output from NLDAS (North American Land Data Assimilation System). The disaggregation model was built at 1/8o spatial resolution on monthly basis and was implemented to calculate and disaggregate SMAP 36 km SM retrievals to 1 km resolution in Oklahoma. The SM disaggregation results were also validated using MESONET (Mesoscale Network) and MICRONET (Microscale Network) ground SM measurements.

Sim3C: simulation of Hi-C and Meta3C proximity ligation sequencing technologies.

PubMed

DeMaere, Matthew Z; Darling, Aaron E

2018-02-01

Chromosome conformation capture (3C) and Hi-C DNA sequencing methods have rapidly advanced our understanding of the spatial organization of genomes and metagenomes. Many variants of these protocols have been developed, each with their own strengths. Currently there is no systematic means for simulating sequence data from this family of sequencing protocols, potentially hindering the advancement of algorithms to exploit this new datatype. We describe a computational simulator that, given simple parameters and reference genome sequences, will simulate Hi-C sequencing on those sequences. The simulator models the basic spatial structure in genomes that is commonly observed in Hi-C and 3C datasets, including the distance-decay relationship in proximity ligation, differences in the frequency of interaction within and across chromosomes, and the structure imposed by cells. A means to model the 3D structure of randomly generated topologically associating domains is provided. The simulator considers several sources of error common to 3C and Hi-C library preparation and sequencing methods, including spurious proximity ligation events and sequencing error. We have introduced the first comprehensive simulator for 3C and Hi-C sequencing protocols. We expect the simulator to have use in testing of Hi-C data analysis algorithms, as well as more general value for experimental design, where questions such as the required depth of sequencing, enzyme choice, and other decisions can be made in advance in order to ensure adequate statistical power with respect to experimental hypothesis testing.

Relationships Between Long-Range Lightning Networks and TRMM/LIS Observations

NASA Technical Reports Server (NTRS)

Rudlosky, Scott D.; Holzworth, Robert H.; Carey, Lawrence D.; Schultz, Chris J.; Bateman, Monte; Cummins, Kenneth L.; Cummins, Kenneth L.; Blakeslee, Richard J.; Goodman, Steven J.

2012-01-01

Recent advances in long-range lightning detection technologies have improved our understanding of thunderstorm evolution in the data sparse oceanic regions. Although the expansion and improvement of long-range lightning datasets have increased their applicability, these applications (e.g., data assimilation, atmospheric chemistry, and aviation weather hazards) require knowledge of the network detection capabilities. The present study intercompares long-range lightning data with observations from the Lightning Imaging Sensor (LIS) aboard the Tropical Rainfall Measurement Mission (TRMM) satellite. The study examines network detection efficiency and location accuracy relative to LIS observations, describes spatial variability in these performance metrics, and documents the characteristics of LIS flashes that are detected by the long-range networks. Improved knowledge of relationships between these datasets will allow researchers, algorithm developers, and operational users to better prepare for the spatial and temporal coverage of the upcoming GOES-R Geostationary Lightning Mapper (GLM).

Evaluation of Long-Range Lightning Detection Networks Using TRMM/LIS Observations

NASA Technical Reports Server (NTRS)

Rudlosky, Scott D.; Holzworth, Robert H.; Carey, Lawrence D.; Schultz, Chris J.; Bateman, Monte; Cecil, Daniel J.; Cummins, Kenneth L.; Petersen, Walter A.; Blakeslee, Richard J.; Goodman, Steven J.

2011-01-01

Recent advances in long-range lightning detection technologies have improved our understanding of thunderstorm evolution in the data sparse oceanic regions. Although the expansion and improvement of long-range lightning datasets have increased their applicability, these applications (e.g., data assimilation, atmospheric chemistry, and aviation weather hazards) require knowledge of the network detection capabilities. Toward this end, the present study evaluates data from the World Wide Lightning Location Network (WWLLN) using observations from the Lightning Imaging Sensor (LIS) aboard the Tropical Rainfall Measurement Mission (TRMM) satellite. The study documents the WWLLN detection efficiency and location accuracy relative to LIS observations, describes the spatial variability in these performance metrics, and documents the characteristics of LIS flashes that are detected by WWLLN. Improved knowledge of the WWLLN detection capabilities will allow researchers, algorithm developers, and operational users to better prepare for the spatial and temporal coverage of the upcoming GOES-R Geostationary Lightning Mapper (GLM).

High resolution observations of low contrast phenomena from an Advanced Geosynchronous Platform (AGP)

NASA Technical Reports Server (NTRS)

Maxwell, M. S.

1984-01-01

Present technology allows radiometric monitoring of the Earth, ocean and atmosphere from a geosynchronous platform with good spatial, spectral and temporal resolution. The proposed system could provide a capability for multispectral remote sensing with a 50 m nadir spatial resolution in the visible bands, 250 m in the 4 micron band and 1 km in the 11 micron thermal infrared band. The diffraction limited telescope has a 1 m aperture, a 10 m focal length (with a shorter focal length in the infrared) and linear and area arrays of detectors. The diffraction limited resolution applies to scenes of any brightness but for a dark low contrast scenes, the good signal to noise ratio of the system contribute to the observation capability. The capabilities of the AGP system are assessed for quantitative observations of ocean scenes. Instrument and ground system configuration are presented and projected sensor capabilities are analyzed.

Scattering attributes of one-dimensional semiconducting oxide nanomaterials individually probed for varying light-matter interaction angles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Daniel S.; Singh, Manpreet; Zhou, Hebing

2015-10-12

We report the characteristic optical responses of one-dimensional semiconducting oxide nanomaterials by examining the individual nanorods (NRs) of ZnO, SnO{sub 2}, indium tin oxide, and zinc tin oxide under precisely controlled, light-matter interaction geometry. Scattering signals from a large set of NRs of the different types are evaluated spatially along the NR length while varying the NR tilt angle, incident light polarization, and analyzer rotation. Subsequently, we identify material-indiscriminate, NR tilt angle- and incident polarization-dependent scattering behaviors exhibiting continuous, intermittent, and discrete responses. The insight gained from this study can advance our fundamental understanding of the optical behaviors of themore » technologically useful nanomaterials and, at the same time, promote the development of highly miniaturized, photonic and bio-optical devices utilizing the spatially controllable, optical responses of the individual semiconducting oxide NRs.« less

Geographic information systems in public health and medicine.

PubMed

Mullner, Ross M; Chung, Kyusuk; Croke, Kevin G; Mensah, Edward K

2004-06-01

Geographic information systems (GIS) are increasingly being used in public health and medicine. Advances in computer technology, the encouragement of its use by the federal government, and the wide availability of academic and commercial courses on GIS are responsible for its growth. Some view GIS as only a tool for spatial research and policy analysis, while others believe it is part of a larger emerging new science including geography, cartography, geodesy, and remote sensing. The specific advantages and problems of GIS are discussed. The greatest potential of GIS is its ability to clearly show the results of complex analyses through maps. Problems in using GIS include its costs, the need to adequately train staff, the use of appropriate spatial units, and the risk it poses to violating patient confidentiality. Lastly, the fourteen articles in this special issue devoted to GIS are introduced and briefly discussed.

Hyperspectral imaging for non-contact analysis of forensic traces.

PubMed

Edelman, G J; Gaston, E; van Leeuwen, T G; Cullen, P J; Aalders, M C G

2012-11-30

Hyperspectral imaging (HSI) integrates conventional imaging and spectroscopy, to obtain both spatial and spectral information from a specimen. This technique enables investigators to analyze the chemical composition of traces and simultaneously visualize their spatial distribution. HSI offers significant potential for the detection, visualization, identification and age estimation of forensic traces. The rapid, non-destructive and non-contact features of HSI mark its suitability as an analytical tool for forensic science. This paper provides an overview of the principles, instrumentation and analytical techniques involved in hyperspectral imaging. We describe recent advances in HSI technology motivating forensic science applications, e.g. the development of portable and fast image acquisition systems. Reported forensic science applications are reviewed. Challenges are addressed, such as the analysis of traces on backgrounds encountered in casework, concluded by a summary of possible future applications. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Chromatin Insulators and Topological Domains: Adding New Dimensions to 3D Genome Architecture

PubMed Central

Matharu, Navneet K.; Ahanger, Sajad H.

2015-01-01

The spatial organization of metazoan genomes has a direct influence on fundamental nuclear processes that include transcription, replication, and DNA repair. It is imperative to understand the mechanisms that shape the 3D organization of the eukaryotic genomes. Chromatin insulators have emerged as one of the central components of the genome organization tool-kit across species. Recent advancements in chromatin conformation capture technologies have provided important insights into the architectural role of insulators in genomic structuring. Insulators are involved in 3D genome organization at multiple spatial scales and are important for dynamic reorganization of chromatin structure during reprogramming and differentiation. In this review, we will discuss the classical view and our renewed understanding of insulators as global genome organizers. We will also discuss the plasticity of chromatin structure and its re-organization during pluripotency and differentiation and in situations of cellular stress. PMID:26340639

Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.

PubMed

He, Bin; Sohrabpour, Abbas; Brown, Emery; Liu, Zhongming

2018-06-04

Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications.

Uses of virtual reality for diagnosis, rehabilitation and study of unilateral spatial neglect: review and analysis.

PubMed

Tsirlin, Inna; Dupierrix, Eve; Chokron, Sylvie; Coquillart, Sabine; Ohlmann, Theophile

2009-04-01

Unilateral spatial neglect is a disabling condition frequently occurring after stroke. People with neglect suffer from various spatial deficits in several modalities, which in many cases impair everyday functioning. A successful treatment is yet to be found. Several techniques have been proposed in the last decades, but only a few showed long-lasting effects and none could completely rehabilitate the condition. Diagnostic methods of neglect could be improved as well. The disorder is normally diagnosed with pen-and-paper methods, which generally do not assess patients in everyday tasks and do not address some forms of the disorder. Recently, promising new methods based on virtual reality have emerged. Virtual reality technologies hold great opportunities for the development of effective assessment and treatment techniques for neglect because they provide rich, multimodal, and highly controllable environments. In order to stimulate advancements in this domain, we present a review and an analysis of the current work. We describe past and ongoing research of virtual reality applications for unilateral neglect and discuss the existing problems and new directions for development.

Error analysis for creating 3D face templates based on cylindrical quad-tree structure

NASA Astrophysics Data System (ADS)

Gutfeter, Weronika

2015-09-01

Development of new biometric algorithms is parallel to advances in technology of sensing devices. Some of the limitations of the current face recognition systems may be eliminated by integrating 3D sensors into these systems. Depth sensing devices can capture a spatial structure of the face in addition to the texture and color. This kind of data is yet usually very voluminous and requires large amount of computer resources for being processed (face scans obtained with typical depth cameras contain more than 150 000 points per face). That is why defining efficient data structures for processing spatial images is crucial for further development of 3D face recognition methods. The concept described in this work fulfills the aforementioned demands. Modification of the quad-tree structure was chosen because it can be easily transformed into less dimensional data structures and maintains spatial relations between data points. We are able to interpret data stored in the tree as a pyramid of features which allow us to analyze face images using coarse-to-fine strategy, often exploited in biometric recognition systems.

Energy Storage (II): Developing Advanced Technologies

ERIC Educational Resources Information Center

Robinson, Arthur L

1974-01-01

Energy storage, considered by some scientists to be the best technological and economic advancement after advanced nuclear power, still rates only modest funding for research concerning the development of advanced technologies. (PEB)

10 CFR 611.3 - Advanced technology vehicle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is an...

10 CFR 611.3 - Advanced technology vehicle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is an...

10 CFR 611.3 - Advanced technology vehicle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is an...

10 CFR 611.3 - Advanced technology vehicle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is an...

10 CFR 611.3 - Advanced technology vehicle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Advanced technology vehicle. 611.3 Section 611.3 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM General § 611.3 Advanced technology vehicle. In order to demonstrate that a vehicle is an...

Advanced Instrumentation for Transient Reactor Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corradini, Michael L.; Anderson, Mark; Imel, George

Transient testing involves placing fuel or material into the core of specialized materials test reactors that are capable of simulating a range of design basis accidents, including reactivity insertion accidents, that require the reactor produce short bursts of intense highpower neutron flux and gamma radiation. Testing fuel behavior in a prototypic neutron environment under high-power, accident-simulation conditions is a key step in licensing nuclear fuels for use in existing and future nuclear power plants. Transient testing of nuclear fuels is needed to develop and prove the safety basis for advanced reactors and fuels. In addition, modern fuel development and designmore » increasingly relies on modeling and simulation efforts that must be informed and validated using specially designed material performance separate effects studies. These studies will require experimental facilities that are able to support variable scale, highly instrumented tests providing data that have appropriate spatial and temporal resolution. Finally, there are efforts now underway to develop advanced light water reactor (LWR) fuels with enhanced performance and accident tolerance. These advanced reactor designs will also require new fuel types. These new fuels need to be tested in a controlled environment in order to learn how they respond to accident conditions. For these applications, transient reactor testing is needed to help design fuels with improved performance. In order to maximize the value of transient testing, there is a need for in-situ transient realtime imaging technology (e.g., the neutron detection and imaging system like the hodoscope) to see fuel motion during rapid transient excursions with a higher degree of spatial and temporal resolution and accuracy. There also exists a need for new small, compact local sensors and instrumentation that are capable of collecting data during transients (e.g., local displacements, temperatures, thermal conductivity, neutron flux, etc.).« less

Extreme weather and climate events with ecological relevance: a review

PubMed Central

Meehl, Gerald A.

2017-01-01

Robust evidence exists that certain extreme weather and climate events, especially daily temperature and precipitation extremes, have changed in regard to intensity and frequency over recent decades. These changes have been linked to human-induced climate change, while the degree to which climate change impacts an individual extreme climate event (ECE) is more difficult to quantify. Rapid progress in event attribution has recently been made through improved understanding of observed and simulated climate variability, methods for event attribution and advances in numerical modelling. Attribution for extreme temperature events is stronger compared with other event types, notably those related to the hydrological cycle. Recent advances in the understanding of ECEs, both in observations and their representation in state-of-the-art climate models, open new opportunities for assessing their effect on human and natural systems. Improved spatial resolution in global climate models and advances in statistical and dynamical downscaling now provide climatic information at appropriate spatial and temporal scales. Together with the continued development of Earth System Models that simulate biogeochemical cycles and interactions with the biosphere at increasing complexity, these make it possible to develop a mechanistic understanding of how ECEs affect biological processes, ecosystem functioning and adaptation capabilities. Limitations in the observational network, both for physical climate system parameters and even more so for long-term ecological monitoring, have hampered progress in understanding bio-physical interactions across a range of scales. New opportunities for assessing how ECEs modulate ecosystem structure and functioning arise from better scientific understanding of ECEs coupled with technological advances in observing systems and instrumentation. This article is part of the themed issue ‘Behavioural, ecological and evolutionary responses to extreme climatic events’. PMID:28483866

Extreme weather and climate events with ecological relevance: a review.

PubMed

Ummenhofer, Caroline C; Meehl, Gerald A

2017-06-19

Robust evidence exists that certain extreme weather and climate events, especially daily temperature and precipitation extremes, have changed in regard to intensity and frequency over recent decades. These changes have been linked to human-induced climate change, while the degree to which climate change impacts an individual extreme climate event (ECE) is more difficult to quantify. Rapid progress in event attribution has recently been made through improved understanding of observed and simulated climate variability, methods for event attribution and advances in numerical modelling. Attribution for extreme temperature events is stronger compared with other event types, notably those related to the hydrological cycle. Recent advances in the understanding of ECEs, both in observations and their representation in state-of-the-art climate models, open new opportunities for assessing their effect on human and natural systems. Improved spatial resolution in global climate models and advances in statistical and dynamical downscaling now provide climatic information at appropriate spatial and temporal scales. Together with the continued development of Earth System Models that simulate biogeochemical cycles and interactions with the biosphere at increasing complexity, these make it possible to develop a mechanistic understanding of how ECEs affect biological processes, ecosystem functioning and adaptation capabilities. Limitations in the observational network, both for physical climate system parameters and even more so for long-term ecological monitoring, have hampered progress in understanding bio-physical interactions across a range of scales. New opportunities for assessing how ECEs modulate ecosystem structure and functioning arise from better scientific understanding of ECEs coupled with technological advances in observing systems and instrumentation.This article is part of the themed issue 'Behavioural, ecological and evolutionary responses to extreme climatic events'. © 2017 The Author(s).

77 FR 32570 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-01

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

76 FR 29195 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

75 FR 60082 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT), National...

78 FR 292 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

76 FR 2662 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of partially closed meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT...

78 FR 57839 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

76 FR 59659 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-27

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

77 FR 3232 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-23

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

78 FR 29704 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-21

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee...

Optical 3D printing: bridging the gaps in the mesoscale

NASA Astrophysics Data System (ADS)

Jonušauskas, Linas; Juodkazis, Saulius; Malinauskas, Mangirdas

2018-05-01

Over the last decade, optical 3D printing has proved itself to be a flexible and capable approach in fabricating an increasing variety of functional structures. One of the main reasons why this technology has become so prominent is the fact that it allows the creation of objects in the mesoscale, where structure dimensions range from nanometers to centimeters. At this scale, the size and spatial configuration of produced single features start to influence the characteristics of the whole object, enabling an array of new, exotic and otherwise unachievable properties and structures (i.e. metamaterials). Here, we present the advantages of this technology in creating mesoscale structures in comparison to subtractive manufacturing techniques and to other branches of 3D printing. Differences between stereolithography, sintering, laser-induced forward transfer and femtosecond laser 3D multi-photon polymerization are highlighted. Attention is given to the discussion of applicable light sources, as well as to an ongoing analysis of the light–matter interaction mechanisms, as they determine the processable materials, required technological steps and the fidelity of feature sizes in fabricated patterns and workpieces. Optical 3D printing-enabled functional structures in micromechanics, medicine, microfluidics, micro-optics and photonics are discussed, with an emphasis on how this particular technology benefits advances in those fields. 4D printing, achieved by varying both the architecture and spatial material composition of the 3D structure, feature-size reduction via stimulated emission depletion-inspired nanolithography or thermal post-treatment, as well as plasmonic nanoparticle-polymer nanocomposites, are presented among examples of the newest trends in the development of this technology. Finally, an outlook is given, examining further scientific frontiers in the field as well as possibilities and challenges in transferring laboratory-level know-how to industrial-scale production.

The Complete Picture: "Standards for Technological Literacy" and "Advancing Excellence in Technological Literacy."

ERIC Educational Resources Information Center

Technology Teacher, 2003

2003-01-01

Provides an overview of the "Standards for Technological Literacy: Content for the Study of Technology" (STL) and "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards" (AETL). Shows how the documents work together to advance the technological literacy of technology educators and K-12…

High-Speed, Three Dimensional Object Composition Mapping Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ishikawa, M Y

2001-02-14

This document overviews an entirely new approach to determining the composition--the chemical-elemental, isotopic and molecular make-up--of complex, highly structured objects, moreover with microscopic spatial resolution in all 3 dimensions. The front cover depicts the new type of pulsed laser system at the heart of this novel technology under adjustment by Alexis Wynne, and schematically indicates two of its early uses: swiftly analyzing the 3-D composition governed structure of a transistor circuit with both optical and mass-spectrometric detectors, and of fossilized dinosaur and turtle bones high-speed probed by optical detection means. Studying the composition-cued 3-D micro-structures of advanced composite materials andmore » the microscopic scale composition-texture of biological tissues are two near-term examples of the rich spectrum of novel applications enabled by this field-opening analytic tool-set.« less

47 CFR 51.230 - Presumption of acceptability for deployment of an advanced services loop technology.

Code of Federal Regulations, 2010 CFR

2010-10-01

... an advanced services loop technology. 51.230 Section 51.230 Telecommunication FEDERAL COMMUNICATIONS... Carriers § 51.230 Presumption of acceptability for deployment of an advanced services loop technology. (a) An advanced services loop technology is presumed acceptable for deployment under any one of the...

Automation method to identify the geological structure of seabed using spatial statistic analysis of echo sounding data

NASA Astrophysics Data System (ADS)

Kwon, O.; Kim, W.; Kim, J.

2017-12-01

Recently construction of subsea tunnel has been increased globally. For safe construction of subsea tunnel, identifying the geological structure including fault at design and construction stage is more than important. Then unlike the tunnel in land, it's very difficult to obtain the data on geological structure because of the limit in geological survey. This study is intended to challenge such difficulties in a way of developing the technology to identify the geological structure of seabed automatically by using echo sounding data. When investigation a potential site for a deep subsea tunnel, there is the technical and economical limit with borehole of geophysical investigation. On the contrary, echo sounding data is easily obtainable while information reliability is higher comparing to above approaches. This study is aimed at developing the algorithm that identifies the large scale of geological structure of seabed using geostatic approach. This study is based on theory of structural geology that topographic features indicate geological structure. Basic concept of algorithm is outlined as follows; (1) convert the seabed topography to the grid data using echo sounding data, (2) apply the moving window in optimal size to the grid data, (3) estimate the spatial statistics of the grid data in the window area, (4) set the percentile standard of spatial statistics, (5) display the values satisfying the standard on the map, (6) visualize the geological structure on the map. The important elements in this study include optimal size of moving window, kinds of optimal spatial statistics and determination of optimal percentile standard. To determine such optimal elements, a numerous simulations were implemented. Eventually, user program based on R was developed using optimal analysis algorithm. The user program was designed to identify the variations of various spatial statistics. It leads to easy analysis of geological structure depending on variation of spatial statistics by arranging to easily designate the type of spatial statistics and percentile standard. This research was supported by the Korea Agency for Infrastructure Technology Advancement under the Ministry of Land, Infrastructure and Transport of the Korean government. (Project Number: 13 Construction Research T01)

Additive Manufacturing/Diagnostics via the High Frequency Induction Heating of Metal Powders: The Determination of the Power Transfer Factor for Fine Metallic Spheres

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rios, Orlando; Radhakrishnan, Balasubramaniam; Caravias, George

2015-03-11

Grid Logic Inc. is developing a method for sintering and melting fine metallic powders for additive manufacturing using spatially-compact, high-frequency magnetic fields called Micro-Induction Sintering (MIS). One of the challenges in advancing MIS technology for additive manufacturing is in understanding the power transfer to the particles in a powder bed. This knowledge is important to achieving efficient power transfer, control, and selective particle heating during the MIS process needed for commercialization of the technology. The project s work provided a rigorous physics-based model for induction heating of fine spherical particles as a function of frequency and particle size. This simulationmore » improved upon Grid Logic s earlier models and provides guidance that will make the MIS technology more effective. The project model will be incorporated into Grid Logic s power control circuit of the MIS 3D printer product and its diagnostics technology to optimize the sintering process for part quality and energy efficiency.« less

NASA World Wind Near Real Time Data for Earth

NASA Astrophysics Data System (ADS)

Hogan, P.

2013-12-01

Innovation requires open standards for data exchange, not to mention ^access to data^ so that value-added, the information intelligence, can be continually created and advanced by the larger community. Likewise, innovation by academia and entrepreneurial enterprise alike, are greatly benefited by an open platform that provides the basic technology for access and visualization of that data. NASA World Wind Java, and now NASA World Wind iOS for the iPhone and iPad, provides that technology. Whether the interest is weather science or climate science, emergency response or supply chain, seeing spatial data in its native context of Earth accelerates understanding and improves decision-making. NASA World Wind open source technology provides the basic elements for 4D visualization, using Open Geospatial Consortium (OGC) protocols, while allowing for customized access to any data, big or small, including support for NetCDF. NASA World Wind includes access to a suite of US Government WMS servers with near real time data. The larger community can readily capitalize on this technology, building their own value-added applications, either open or proprietary. Night lights heat map Glacier National Park

Multiplexed lateral flow biosensors: Technological advances for radically improving point-of-care diagnoses.

PubMed

Li, Jia; Macdonald, Joanne

2016-09-15

Lateral flow biosensors are a leading technology in point-of-care diagnostics due to their simplicity, rapidness and low cost. Their primacy in this arena continues through technological breakthroughs such as multiplexing: the detection of more than one biomarker in a single assay. Multiplexing capacity is critical for improving diagnostic efficiency, enhancing the diagnostic precision for specific diseases and reducing diagnostic cost. Here we review, for the first time, the various types and strategies employed for creating multiplexed lateral flow biosensors. These are classified into four main categories in terms of specific application or multiplexing level, namely linear, parameter, spatial and conceptual. We describe the practical applications and implications for each approach and compare their advantages and disadvantages. Importantly, multiplexing is still subject to limitations of the traditional lateral flow biosensor, such as sensitivity and specificity. However, by pushing the limitations of the traditional medium into the multiplex arena, several technological breakthroughs are emerging with novel solutions that further expand the utility of lateral flow biosensing for point-of-care applications. Copyright © 2016 Elsevier B.V. All rights reserved.

Spatial Visualization--A Gateway to Computer-Based Technology.

ERIC Educational Resources Information Center

Norman, Kent L.

1994-01-01

A model is proposed for the influence of individual differences on performance when computer-based technology is introduced. The primary cognitive factor driving differences in performance is spatial visualization ability. Four techniques for mitigating the negative impact of low spatial visualization are discussed: spatial metaphors, graphical…

Sensors in the Stream: The High-Frequency Wave of the Present.

PubMed

Rode, Michael; Wade, Andrew J; Cohen, Matthew J; Hensley, Robert T; Bowes, Michael J; Kirchner, James W; Arhonditsis, George B; Jordan, Phil; Kronvang, Brian; Halliday, Sarah J; Skeffington, Richard A; Rozemeijer, Joachim C; Aubert, Alice H; Rinke, Karsten; Jomaa, Seifeddine

2016-10-04

New scientific understanding is catalyzed by novel technologies that enhance measurement precision, resolution or type, and that provide new tools to test and develop theory. Over the last 50 years, technology has transformed the hydrologic sciences by enabling direct measurements of watershed fluxes (evapotranspiration, streamflow) at time scales and spatial extents aligned with variation in physical drivers. High frequency water quality measurements, increasingly obtained by in situ water quality sensors, are extending that transformation. Widely available sensors for some physical (temperature) and chemical (conductivity, dissolved oxygen) attributes have become integral to aquatic science, and emerging sensors for nutrients, dissolved CO 2 , turbidity, algal pigments, and dissolved organic matter are now enabling observations of watersheds and streams at time scales commensurate with their fundamental hydrological, energetic, elemental, and biological drivers. Here we synthesize insights from emerging technologies across a suite of applications, and envision future advances, enabled by sensors, in our ability to understand, predict, and restore watershed and stream systems.

3D Bioprinting for Organ Regeneration

PubMed Central

Cui, Haitao; Nowicki, Margaret; Fisher, John P.; Zhang, Lijie Grace

2017-01-01

Regenerative medicine holds the promise of engineering functional tissues or organs to heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap between organ shortage and transplantation needs. Three-dimensional (3D) bioprinting is evolving into an unparalleled bio-manufacturing technology due to its high-integration potential for patient-specific designs, precise and rapid manufacturing capabilities with high resolution, and unprecedented versatility. It enables precise control over multiple compositions, spatial distributions, and architectural accuracy/complexity, therefore achieving effective recapitulation of microstructure, architecture, mechanical properties, and biological functions of target tissues and organs. Here we provide an overview of recent advances in 3D bioprinting technology, as well as design concepts of bioinks suitable for the bioprinting process. We focus on the applications of this technology for engineering living organs, focusing more specifically on vasculature, neural networks, the heart and liver. We conclude with current challenges and the technical perspective for further development of 3D organ bioprinting. PMID:27995751

Material design and engineering of next-generation flow-battery technologies

NASA Astrophysics Data System (ADS)

Park, Minjoon; Ryu, Jaechan; Wang, Wei; Cho, Jaephil

2017-01-01

Spatial separation of the electrolyte and electrode is the main characteristic of flow-battery technologies, which liberates them from the constraints of overall energy content and the energy/power ratio. The concept of a flowing electrolyte not only presents a cost-effective approach for large-scale energy storage, but has also recently been used to develop a wide range of new hybrid energy storage and conversion systems. The advent of flow-based lithium-ion, organic redox-active materials, metal-air cells and photoelectrochemical batteries promises new opportunities for advanced electrical energy-storage technologies. In this Review, we present a critical overview of recent progress in conventional aqueous redox-flow batteries and next-generation flow batteries, highlighting the latest innovative alternative materials. We outline their technical feasibility for use in long-term and large-scale electrical energy-storage devices, as well as the limitations that need to be overcome, providing our view of promising future research directions in the field of redox-flow batteries.

3D Miniaturization of Human Organs for Drug Discovery.

PubMed

Park, Joseph; Wetzel, Isaac; Dréau, Didier; Cho, Hansang

2018-01-01

"Engineered human organs" hold promises for predicting the effectiveness and accuracy of drug responses while reducing cost, time, and failure rates in clinical trials. Multiorgan human models utilize many aspects of currently available technologies including self-organized spherical 3D human organoids, microfabricated 3D human organ chips, and 3D bioprinted human organ constructs to mimic key structural and functional properties of human organs. They enable precise control of multicellular activities, extracellular matrix (ECM) compositions, spatial distributions of cells, architectural organizations of ECM, and environmental cues. Thus, engineered human organs can provide the microstructures and biological functions of target organs and advantageously substitute multiscaled drug-testing platforms including the current in vitro molecular assays, cell platforms, and in vivo models. This review provides an overview of advanced innovative designs based on the three main technologies used for organ construction leading to single and multiorgan systems useable for drug development. Current technological challenges and future perspectives are also discussed. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

3D Bioprinting for Organ Regeneration.

PubMed

Cui, Haitao; Nowicki, Margaret; Fisher, John P; Zhang, Lijie Grace

2017-01-01

Regenerative medicine holds the promise of engineering functional tissues or organs to heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap between organ shortage and transplantation needs. Three-dimensional (3D) bioprinting is evolving into an unparalleled biomanufacturing technology due to its high-integration potential for patient-specific designs, precise and rapid manufacturing capabilities with high resolution, and unprecedented versatility. It enables precise control over multiple compositions, spatial distributions, and architectural accuracy/complexity, therefore achieving effective recapitulation of microstructure, architecture, mechanical properties, and biological functions of target tissues and organs. Here we provide an overview of recent advances in 3D bioprinting technology, as well as design concepts of bioinks suitable for the bioprinting process. We focus on the applications of this technology for engineering living organs, focusing more specifically on vasculature, neural networks, the heart and liver. We conclude with current challenges and the technical perspective for further development of 3D organ bioprinting. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

GHGs and air pollutants embodied in China's international trade: Temporal and spatial index decomposition analysis.

PubMed

Liu, Zhengyan; Mao, Xianqiang; Song, Peng

2017-01-01

Temporal index decomposition analysis and spatial index decomposition analysis were applied to understand the driving forces of the emissions embodied in China's exports and net exports during 2002-2011, respectively. The accumulated emissions embodied in exports accounted for approximately 30% of the total emissions in China; although the contribution of the sectoral total emissions intensity (technique effect) declined, the scale effect was largely responsible for the mounting emissions associated with export, and the composition effect played a largely insignificant role. Calculations of the emissions embodied in net exports suggest that China is generally in an environmentally inferior position compared with its major trade partners. The differences in the economy-wide emission intensities between China and its major trade partners were the biggest contribution to this reality, and the trade balance effect played a less important role. However, a lower degree of specialization in pollution intensive products in exports than in imports helped to reduce slightly the emissions embodied in net exports. The temporal index decomposition analysis results suggest that China should take effective measures to optimize export and supply-side structure and reduce the total emissions intensity. According to spatial index decomposition analysis, it is suggested that a more aggressive import policy was useful for curbing domestic and global emissions, and the transfer of advanced production technologies and emission control technologies from developed to developing countries should be a compulsory global environmental policy option to mitigate the possible leakage of pollution emissions caused by international trade.

Increased Genomic Prediction Accuracy in Wheat Breeding Through Spatial Adjustment of Field Trial Data

PubMed Central

Lado, Bettina; Matus, Ivan; Rodríguez, Alejandra; Inostroza, Luis; Poland, Jesse; Belzile, François; del Pozo, Alejandro; Quincke, Martín; Castro, Marina; von Zitzewitz, Jarislav

2013-01-01

In crop breeding, the interest of predicting the performance of candidate cultivars in the field has increased due to recent advances in molecular breeding technologies. However, the complexity of the wheat genome presents some challenges for applying new technologies in molecular marker identification with next-generation sequencing. We applied genotyping-by-sequencing, a recently developed method to identify single-nucleotide polymorphisms, in the genomes of 384 wheat (Triticum aestivum) genotypes that were field tested under three different water regimes in Mediterranean climatic conditions: rain-fed only, mild water stress, and fully irrigated. We identified 102,324 single-nucleotide polymorphisms in these genotypes, and the phenotypic data were used to train and test genomic selection models intended to predict yield, thousand-kernel weight, number of kernels per spike, and heading date. Phenotypic data showed marked spatial variation. Therefore, different models were tested to correct the trends observed in the field. A mixed-model using moving-means as a covariate was found to best fit the data. When we applied the genomic selection models, the accuracy of predicted traits increased with spatial adjustment. Multiple genomic selection models were tested, and a Gaussian kernel model was determined to give the highest accuracy. The best predictions between environments were obtained when data from different years were used to train the model. Our results confirm that genotyping-by-sequencing is an effective tool to obtain genome-wide information for crops with complex genomes, that these data are efficient for predicting traits, and that correction of spatial variation is a crucial ingredient to increase prediction accuracy in genomic selection models. PMID:24082033

An Overview of Future NASA Missions, Concepts, and Technologies Related to Imaging of the World's Land Areas

NASA Technical Reports Server (NTRS)

Salomonson, Vincent V.

1999-01-01

In the near term NASA is entering into the peak activity period of the Earth Observing System (EOS). The EOS AM-1 /"Terra" spacecraft is nearing launch and operation to be followed soon by the New Millennium Program (NMP) Earth Observing (EO-1) mission. Other missions related to land imaging and studies include EOS PM-1 mission, the Earth System Sciences Program (ESSP) Vegetation Canopy Lidar (VCL) mission, the EOS/IceSat mission. These missions involve clear advances in technologies and observational capability including improvements in multispectral imaging and other observing strategies, for example, "formation flying". Plans are underway to define the next era of EOS missions, commonly called "EOS Follow-on" or EOS II. The programmatic planning includes concepts that represent advances over the present Landsat-7 mission that concomitantly recognize the advances being made in land imaging within the private sector. The National Polar Orbiting Environmental Satellite Series (NPOESS) Preparatory Project (NPP) is an effort that will help to transition EOS medium resolution (herein meaning spatial resolutions near 500 meters), multispectral measurement capabilities such as represented by the EOS Moderate Resolution Imaging Spectroradiometer (MODIS) into the NPOESS operational series of satellites. Developments in Synthetic Aperture Radar (SAR) and passive microwave land observing capabilities are also proceeding. Beyond these efforts the Earth Science Enterprise Technology Strategy is embarking efforts to advance technologies in several basic areas: instruments, flight systems and operational capability, and information systems. In the case of instruments architectures will be examined that offer significant reductions in mass, volume, power and observational flexibility. For flight systems and operational capability, formation flying including calibration and data fusion, systems operation autonomy, and mechanical and electronic innovations that can reduce spacecraft and subsystem resource requirements. The efforts in information systems will include better approaches for linking multiple data sets, extracting and visualizing information, and improvements in collecting, compressing, transmitting, processing, distributing and archiving data from multiple platforms. Overall concepts such as sensor webs, constellations of observing systems, and rapid and tailored data availability and delivery to multiple users comprise and notions Earth Science Vision for the future.

Concept and Practice of Teaching Technical University Students to Modern Technologies of 3d Data Acquisition and Processing: a Case Study of Close-Range Photogrammetry and Terrestrial Laser Scanning

NASA Astrophysics Data System (ADS)

Kravchenko, Iulia; Luhmann, Thomas; Shults, Roman

2016-06-01

For the preparation of modern specialists in the acquisition and processing of three-dimensional data, a broad and detailed study of related modern methods and technologies is necessary. One of the most progressive and effective methods of acquisition and analyzing spatial data is terrestrial laser scanning. The study of methods and technologies for terrestrial laser scanning is of great importance not only for GIS specialists, but also for surveying engineers who make decisions in traditional engineering tasks (monitoring, executive surveys, etc.). The understanding and formation of the right approach in preparing new professionals need to develop a modern and variable educational program. This educational program must provide effective practical and laboratory work and the student's coursework. The resulting knowledge of the study should form the basis for practical or research of young engineers. In 2014, the Institute of Applied Sciences (Jade University Oldenburg, Germany) and Kyiv National University of Construction and Architecture (Kiev, Ukraine) had launched a joint educational project for the introduction of terrestrial laser scanning technology for collection and processing of spatial data. As a result of this project practical recommendations have been developed for the organization of educational processes in the use of terrestrial laser scanning. An advanced project-oriented educational program was developed which is presented in this paper. In order to demonstrate the effectiveness of the program a 3D model of the big and complex main campus of Kyiv National University of Construction and Architecture has been generated.

Remote Sensing Technologies for Estuary Research and Management (Invited)

NASA Astrophysics Data System (ADS)

Hestir, E. L.; Ustin, S.; Khanna, S.; Botha, E.; Santos, M. J.; Anstee, J.; Greenberg, J. A.

2013-12-01

Estuarine ecosystems and their biogeochemical processes are extremely vulnerable to climate and environmental changes, and are threatened by sea level rise and upstream activities such as land use/land cover and hydrological changes. Despite the recognized threat to estuaries, most aspects of how change will affect estuaries are not well understood due to the poorly resolved understanding of the complex physical, chemical and biological processes and their interactions in estuarine systems. New and innovative remote sensing technologies such as high spectral resolution optical and thermal imagers and lidar, microwave radiometers and radar imagers enable measurements of key environmental parameters needed to establish baseline conditions and improve modeling efforts. Radar's sensitivity to water provides information about water height and velocity, channel geometry and wetland inundation. Water surface temperature and salinity and can be measured from microwave radiometry, and when combined with radar-derived information can provide information about estuarine hydrodynamics. Optical and thermal hyperspectral imagers provide information about sediment, plant and water chemistry including chlorophyll, dissolved organic matter and mineralogical composition. Lidar can measure bathymetry, microtopography and emergent plant structure. Plant functional types, wetland community distributions, turbidity, suspended and deposited sediments, dissolved organic matter, water column chlorophyll and phytoplankton functional types may be estimated from these measurements. Innovative deployment of advanced remote sensing technologies on airborne and submersible un-piloted platforms provides temporally and spatially continuous measurement in temporally dynamic and spatially complex tidal systems. Through biophysically-based retrievals, these technologies provide direct measurement of physical, biological and biogeochemical conditions that can be used as models to understand estuarine processes and forecast responses to change. We demonstrate that innovative remote sensing technologies, coupled with long term datasets from satellite earth observing missions and in situ sensor networks provide the spatially contiguous measurements needed to make 'supra-regional' (e.g. river to coast) assessments of ecological communities, habitat distribution, ecosystem function, sediment, nutrient and carbon source and transport. We show that this information can be used to improve environmental modeling with increased confidence and support informed environmental management.

A Hearing Aid Primer 1

ERIC Educational Resources Information Center

Yetter, Carol J.

2009-01-01

This hearing aid primer is designed to define the differences among the three levels of hearing instrument technology: conventional analog circuit technology (most basic), digitally programmable/analog circuit technology (moderately advanced), and fully digital technology (most advanced). Both moderate and advanced technologies mean that hearing…

Exploiting Advanced Hydrogel Technologies to Address Key Challenges in Regenerative Medicine

PubMed Central

Gentleman, Eileen

2018-01-01

Regenerative medicine aims to tackle a panoply of challenges, from repairing focal damage to articular cartilage to preventing pathological tissue remodelling after myocardial infarction. Hydrogels are water-swollen networks formed from synthetic or naturally derived polymers, and are emerging as important tools to address these challenges. Recent advances in hydrogel chemistries are enabling researchers to create hydrogels that can act as 3D ex vivo tissue models, allowing them to explore fundamental questions in cell biology by replicating tissues’ dynamic and non-linear physical properties. Enabled by emerging techniques such as 3D bioprinting, cell-laden hydrogels are also being developed with highly controlled tissue-specific architectures, vasculature, and biological functions that together can direct tissue repair. Moreover, advanced in situ forming and acellular hydrogels are increasingly finding use as delivery vehicles for bioactive compounds and in mediating host cell response. Here, we review advances in the design and fabrication of hydrogels for regenerative medicine. We also address how controlled chemistries are allowing for precise engineering of spatial and time-dependent properties in hydrogels with a look to how these materials will eventually translate to clinical applications. PMID:29316363

Cognitive correlates of performance in advanced mathematics.

PubMed

Wei, Wei; Yuan, Hongbo; Chen, Chuansheng; Zhou, Xinlin

2012-03-01

Much research has been devoted to understanding cognitive correlates of elementary mathematics performance, but little such research has been done for advanced mathematics (e.g., modern algebra, statistics, and mathematical logic). To promote mathematical knowledge among college students, it is necessary to understand what factors (including cognitive factors) are important for acquiring advanced mathematics. We recruited 80 undergraduates from four universities in Beijing. The current study investigated the associations between students' performance on a test of advanced mathematics and a battery of 17 cognitive tasks on basic numerical processing, complex numerical processing, spatial abilities, language abilities, and general cognitive processing. The results showed that spatial abilities were significantly correlated with performance in advanced mathematics after controlling for other factors. In addition, certain language abilities (i.e., comprehension of words and sentences) also made unique contributions. In contrast, basic numerical processing and computation were generally not correlated with performance in advanced mathematics. Results suggest that spatial abilities and language comprehension, but not basic numerical processing, may play an important role in advanced mathematics. These results are discussed in terms of their theoretical significance and practical implications. ©2011 The British Psychological Society.

Analysis of dynamic brain oscillations: methodological advances.

PubMed

Le Van Quyen, Michel; Bragin, Anatol

2007-07-01

In recent years, new recording technologies have advanced such that, at high temporal and spatial resolutions, oscillations of neuronal networks can be identified from simultaneous, multisite recordings. However, because of the deluge of multichannel data generated by these experiments, achieving the full potential of parallel neuronal recordings also depends on the development of new mathematical methods that can extract meaningful information relating to time, frequency and space. Here, we aim to bridge this gap by focusing on up-to-date recording techniques for measurement of network oscillations and new analysis tools for their quantitative assessment. In particular, we emphasize how these methods can be applied, what property might be inferred from neuronal signals and potentially productive future directions. This review is part of the INMED and TINS special issue, Physiogenic and pathogenic oscillations: the beauty and the beast, derived from presentations at the annual INMED and TINS symposium (http://inmednet.com).

From a meso- to micro-scale connectome: array tomography and mGRASP

PubMed Central

Rah, Jong-Cheol; Feng, Linqing; Druckmann, Shaul; Lee, Hojin; Kim, Jinhyun

2015-01-01

Mapping mammalian synaptic connectivity has long been an important goal of neuroscience because knowing how neurons and brain areas are connected underpins an understanding of brain function. Meeting this goal requires advanced techniques with single synapse resolution and large-scale capacity, especially at multiple scales tethering the meso- and micro-scale connectome. Among several advanced LM-based connectome technologies, Array Tomography (AT) and mammalian GFP-Reconstitution Across Synaptic Partners (mGRASP) can provide relatively high-throughput mapping synaptic connectivity at multiple scales. AT- and mGRASP-assisted circuit mapping (ATing and mGRASPing), combined with techniques such as retrograde virus, brain clearing techniques, and activity indicators will help unlock the secrets of complex neural circuits. Here, we discuss these useful new tools to enable mapping of brain circuits at multiple scales, some functional implications of spatial synaptic distribution, and future challenges and directions of these endeavors. PMID:26089781

Zooming In on Plant Hormone Analysis: Tissue- and Cell-Specific Approaches.

PubMed

Novák, Ondřej; Napier, Richard; Ljung, Karin

2017-04-28

Plant hormones are a group of naturally occurring, low-abundance organic compounds that influence physiological processes in plants. Our knowledge of the distribution profiles of phytohormones in plant organs, tissues, and cells is still incomplete, but advances in mass spectrometry have enabled significant progress in tissue- and cell-type-specific analyses of phytohormones over the last decade. Mass spectrometry is able to simultaneously identify and quantify hormones and their related substances. Biosensors, on the other hand, offer continuous monitoring; can visualize local distributions and real-time quantification; and, in the case of genetically encoded biosensors, are noninvasive. Thus, biosensors offer additional, complementary technologies for determining temporal and spatial changes in phytohormone concentrations. In this review, we focus on recent advances in mass spectrometry-based quantification, describe monitoring systems based on biosensors, and discuss validations of the various methods before looking ahead at future developments for both approaches.

Submicron x-ray diffraction and its applications to problems in materials and environmental science

NASA Astrophysics Data System (ADS)

Tamura, N.; Celestre, R. S.; MacDowell, A. A.; Padmore, H. A.; Spolenak, R.; Valek, B. C.; Meier Chang, N.; Manceau, A.; Patel, J. R.

2002-03-01

The availability of high brilliance third generation synchrotron sources together with progress in achromatic focusing optics allows us to add submicron spatial resolution to the conventional century-old x-ray diffraction technique. The new capabilities include the possibility to map in situ, grain orientations, crystalline phase distribution, and full strain/stress tensors at a very local level, by combining white and monochromatic x-ray microbeam diffraction. This is particularly relevant for high technology industry where the understanding of material properties at a microstructural level becomes increasingly important. After describing the latest advances in the submicron x-ray diffraction techniques at the Advanced Light Source, we will give some examples of its application in material science for the measurement of strain/stress in metallic thin films and interconnects. Its use in the field of environmental science will also be discussed.

Landslide hazard assessment: recent trends and techniques.

PubMed

Pardeshi, Sudhakar D; Autade, Sumant E; Pardeshi, Suchitra S

2013-01-01

Landslide hazard assessment is an important step towards landslide hazard and risk management. There are several methods of Landslide Hazard Zonation (LHZ) viz. heuristic, semi quantitative, quantitative, probabilistic and multi-criteria decision making process. However, no one method is accepted universally for effective assessment of landslide hazards. In recent years, several attempts have been made to apply different methods of LHZ and to compare results in order to find the best suited model. This paper presents the review of researches on landslide hazard mapping published in recent years. The advanced multivariate techniques are proved to be effective in spatial prediction of landslides with high degree of accuracy. Physical process based models also perform well in LHZ mapping even in the areas with poor database. Multi-criteria decision making approach also play significant role in determining relative importance of landslide causative factors in slope instability process. Remote Sensing and Geographical Information System (GIS) are powerful tools to assess landslide hazards and are being used extensively in landslide researches since last decade. Aerial photographs and high resolution satellite data are useful in detection, mapping and monitoring landslide processes. GIS based LHZ models helps not only to map and monitor landslides but also to predict future slope failures. The advancements in Geo-spatial technologies have opened the doors for detailed and accurate assessment of landslide hazards.

From Michelson and Fizeau to a Space-borne Infrared Instrument Capable of Detecting an Earth Twin: Development and Recent Accomplishments of Stellar Interferometry

NASA Technical Reports Server (NTRS)

Barry, Richard K.; Danchi, William C.; Lopez, Bruno; Rinehart, Stephen; Absil, Olivier; Augereau, Jean-Charles; Beust, Herve; Bonfils, Xavier; Borde, Pascal; Defrere, Denis;

Magnetic particle imaging: advancements and perspectives for real-time in vivo monitoring and image-guided therapy

NASA Astrophysics Data System (ADS)

Pablico-Lansigan, Michele H.; Situ, Shu F.; Samia, Anna Cristina S.

2013-05-01

Magnetic particle imaging (MPI) is an emerging biomedical imaging technology that allows the direct quantitative mapping of the spatial distribution of superparamagnetic iron oxide nanoparticles. MPI's increased sensitivity and short image acquisition times foster the creation of tomographic images with high temporal and spatial resolution. The contrast and sensitivity of MPI is envisioned to transcend those of other medical imaging modalities presently used, such as magnetic resonance imaging (MRI), X-ray scans, ultrasound, computed tomography (CT), positron emission tomography (PET) and single photon emission computed tomography (SPECT). In this review, we present an overview of the recent advances in the rapidly developing field of MPI. We begin with a basic introduction of the fundamentals of MPI, followed by some highlights over the past decade of the evolution of strategies and approaches used to improve this new imaging technique. We also examine the optimization of iron oxide nanoparticle tracers used for imaging, underscoring the importance of size homogeneity and surface engineering. Finally, we present some future research directions for MPI, emphasizing the novel and exciting opportunities that it offers as an important tool for real-time in vivo monitoring. All these opportunities and capabilities that MPI presents are now seen as potential breakthrough innovations in timely disease diagnosis, implant monitoring, and image-guided therapeutics.

Advanced Education and Technology Business Plan, 2010-13

ERIC Educational Resources Information Center

Alberta Advanced Education and Technology, 2010

2010-01-01

This paper presents the business plan of the Ministry of Advanced Education and Technology for 2010 to 2013. Advanced Education and Technology supports the advanced learning system by providing funding for advanced learning providers, coordinating and approving programs of study at public institutions, licensing and approving programs at private…

Technology readiness levels for the new millennium program

NASA Technical Reports Server (NTRS)

Moynihan, P. I.; Minning, C. P.; Stocky, J. F.

2003-01-01

NASA's New Millennium Program (NMP) seeks to advance space exploration by providing an in-space validating mechanism to verify the maturity of promising advanced technologies that cannot be adequately validated with Earth-based testing alone. In meeting this objective, NMP uses NASA Technology Readiness Levels (TRL) as key indicators of technology advancement and assesses development progress against this generalized metric. By providing an opportunity for in-space validation, NMP can mature a suitable advanced technology from TRL 4 (component and/or breadboard validation in laboratory environment) to a TRL 7 (system prototype demonstrated in an Earth-based space environment). Spaceflight technology comprises a myriad of categories, types, and functions, and as each individual technology emerges, a consistent interpretation of its specific state of technological advancement relative to other technologies is problematic.

A Potential Synergy Connecting Educational Leadership, The Geoscience Community, and Spatial Data

NASA Astrophysics Data System (ADS)

Branch, B. D.

2008-12-01

The effort to promote more geosciences numbers and greater diversity should reference considerations of federal policy. In congruence, institutions need to include geosciences education in the K-12 curriculum in order to increase the numbers of geoscientists and to increase diversity among geoscientists. For example, No Child Left Behind stated public entities should, ""(1) to carry out programs that prepare prospective teachers to use advanced technology to prepare all students to meet challenging", section 1051 sub section 221. Moreover, Executive Order 12906, the Spatial Data Infrastructure Act, requires all federal agencies to manage their spatial data. Such compliance may influence the job market, education and policy makers to see that spatial thinking transcends the standard course of study. Namely, educational leadership and policy have to be a vital aid to augment the geosciences experience through the K-12 experience and as an inclusion activity in the standard course of study agenda. A simple endorsement by the National Academy of Sciences (2006), in their work titled Learning to think spatially: GIS as a support system in the K-12 curriculum, who stated, "Spatial thinking can be learned, and it can and should be taught at all levels in the education system" (p.3). Such may not be enough to gain the attention and time consideration of educational leadership. Therefore, the challenge for progressive advocates of geosciences is that some may have to consider educational leadership as new frontier to push such policy and research issues.

Achievements of the DOT-NASA Joint Program on Remote Sensing and Spatial Information Technologies: Application to Multimodal Transportation

NASA Technical Reports Server (NTRS)

2002-01-01

This report presents three-year accomplishments from the national program on Commercial Remote Sensing and Geospatial Technology (CRSGT) application to transportation, administered by the U.S. Department of Transportation (U.S. DOT) in collaboration with the National Aeronautics and Space Administration (NASA). The joint program was authorized under Section 5113 of the Transportation Equity Act for the 21st Century (TEA-21). This is the first national program of its type focusing on transportation applications of emerging commercial remote sensing technologies. U.S. DOT's Research and Special Programs Administration manages the program in coordination with NASA's Earth Science Enterprise's application programs. The program focuses on applications of CRSGT products and systems for providing smarter and more efficient transportation operations and services. The program is performed in partnership with four major National Consortia for Remote Sensing in Transportation (NCRST). Each consortium focuses on research and development of products in one of the four priority areas for transportation application, and includes technical application and demonstration projects carried out in partnership with industries and service providers in their respective areas. The report identifies products and accomplishments from each of the four consortia in meeting the goal of providing smarter and more efficient transportation services. The products and results emerging from the program are being implemented in transportation operations and services through state and local agencies. The Environmental Assessment and Application Consortium (NCRST-E) provides leadership for developing and deploying cost effective environmental and transportation planning services, and integrates CRSGT advances for achieving smarter and cost effective corridor planning. The Infrastructure Management Consortium (NCRST-I) provides leadership in technologies that achieve smarter and cheaper ways of managing transportation infrastructure assets, operation, and inspection, and integrates CRSGT advances for achieving infrastructure security. The Traffic Flow Consortium (NCRST-F) provides leadership to develop new tools for regional traffic flow management including heavy vehicles and intermodal flow of freight, and integrates CRSGT advances for complementing and extending the reach of ITS user services. The Safety, Hazards and Disasters (NCRST-H) provides leadership for deploying remote sensing technology to locate transportation hazards and improve disaster recovery, and integrates CRSGT advances for application to protect transportation systems from terrorism. The DOT-NASA team is proud to present this report of accomplishments on products and results emerging from the joint program for application to transportation practice.

Civil propulsion technology for the next twenty-five years

NASA Technical Reports Server (NTRS)

Rosen, Robert; Facey, John R.

1987-01-01

The next twenty-five years will see major advances in civil propulsion technology that will result in completely new aircraft systems for domestic, international, commuter and high-speed transports. These aircraft will include advanced aerodynamic, structural, and avionic technologies resulting in major new system capabilities and economic improvements. Propulsion technologies will include high-speed turboprops in the near term, very high bypass ratio turbofans, high efficiency small engines and advanced cycles utilizing high temperature materials for high-speed propulsion. Key fundamental enabling technologies include increased temperature capability and advanced design methods. Increased temperature capability will be based on improved composite materials such as metal matrix, intermetallics, ceramics, and carbon/carbon as well as advanced heat transfer techniques. Advanced design methods will make use of advances in internal computational fluid mechanics, reacting flow computation, computational structural mechanics and computational chemistry. The combination of advanced enabling technologies, new propulsion concepts and advanced control approaches will provide major improvements in civil aircraft.

TU-AB-204-02: Advances in C-Arm CBCT for Cardiac Interventions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fahrig, R.

This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both themore » likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions, significant effort has been expended to improve the quantitative accuracy of C-arm CBCT reconstructions. The challenge is to improve image quality while providing very short turnaround between data acquisition and volume data visualization. Corrections for x-ray scatter, view aliasing and patient motion that require no more than 2 iterations keep processing time short while reducing artifact. Fast, multi-sweep acquisitions can be used to permit assessment of left ventricular function, and visualization of radiofrequency lesions created to treat arrhythmias. Workflows for each imaging goal have been developed and validated against gold standard clinical CT or histology. The challenges, opportunities, and limitations of the new functional C-arm CBCT imaging techniques will be discussed. Dr. W. Zbijewski (Johns Hopkins University) will present on the topic: Advances in CBCT for Orthopaedics and Bone Health Imaging. Cone-beam CT is particularly well suited for imaging of musculoskeletal extremities. Owing to the high spatial resolution of flat-panel detectors, CBCT can surpass conventional CT in imaging tasks involving bone visualization, quantitative analysis of subchondral trabecular structure, and visualization and monitoring of subtle fractures that are common in orthopedic radiology. A dedicated CBCT platform has been developed that offers flexibility in system design and provides not only a compact configuration with improved logistics for extremities imaging but also enables novel diagnostic capabilities such as imaging of weight-bearing lower extremities in a natural stance. The design, development and clinical performance of dedicated extremities CBCT systems will be presented. Advanced capabilities for quantitative volumetric assessment of joint space morphology, dual-energy image-based quantification of bone composition, and in-vivo analysis of bone microarchitecture will be discussed, along with emerging applications in the diagnosis of arthritis and osteoporosis and assessment of novel therapies. Finally, Dr. J. Boone (UC Davis) will present on the topic: Advances in CBCT for Breast Imaging. Breast CT has been studied as an imaging tool for diagnostic breast evaluation and for potential breast cancer screening. The breast CT application lends itself to CBCT because of the small dimensions of the breast, the tapered shape of the breast towards higher cone angle, and the fact that there are no bones in the breast. The performance of various generations of breast CT scanners developed in recent years will be discussed, focusing on advances in spatial resolution and image noise characteristics. The results will also demonstrate the results of clinical trials using both computer and human observers. Learning Objectives: Understand the challenges, key technological advances, and emerging opportunities of CBCT in: Brain perfusion imaging, including assessment of ischemic stroke Cardiac imaging for functional assessment in cardiac interventions Orthopedics imaging for evaluation of musculoskeletal trauma, arthritis, and osteoporosis Breast imaging for screening and diagnosis of breast cancer. Work presented in this symposium includes research support by: Siemens Healthcare (Dr. Chen); NIH and Siemens Healthcare (Dr. Fahrig); NIH and Carestream Health (Dr. Zbijewski); and NIH (Dr. Boone)« less

TU-AB-204-03: Advances in CBCT for Orhtopaedics and Bone Health Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zbijewski, W.

This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both themore » likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions, significant effort has been expended to improve the quantitative accuracy of C-arm CBCT reconstructions. The challenge is to improve image quality while providing very short turnaround between data acquisition and volume data visualization. Corrections for x-ray scatter, view aliasing and patient motion that require no more than 2 iterations keep processing time short while reducing artifact. Fast, multi-sweep acquisitions can be used to permit assessment of left ventricular function, and visualization of radiofrequency lesions created to treat arrhythmias. Workflows for each imaging goal have been developed and validated against gold standard clinical CT or histology. The challenges, opportunities, and limitations of the new functional C-arm CBCT imaging techniques will be discussed. Dr. W. Zbijewski (Johns Hopkins University) will present on the topic: Advances in CBCT for Orthopaedics and Bone Health Imaging. Cone-beam CT is particularly well suited for imaging of musculoskeletal extremities. Owing to the high spatial resolution of flat-panel detectors, CBCT can surpass conventional CT in imaging tasks involving bone visualization, quantitative analysis of subchondral trabecular structure, and visualization and monitoring of subtle fractures that are common in orthopedic radiology. A dedicated CBCT platform has been developed that offers flexibility in system design and provides not only a compact configuration with improved logistics for extremities imaging but also enables novel diagnostic capabilities such as imaging of weight-bearing lower extremities in a natural stance. The design, development and clinical performance of dedicated extremities CBCT systems will be presented. Advanced capabilities for quantitative volumetric assessment of joint space morphology, dual-energy image-based quantification of bone composition, and in-vivo analysis of bone microarchitecture will be discussed, along with emerging applications in the diagnosis of arthritis and osteoporosis and assessment of novel therapies. Finally, Dr. J. Boone (UC Davis) will present on the topic: Advances in CBCT for Breast Imaging. Breast CT has been studied as an imaging tool for diagnostic breast evaluation and for potential breast cancer screening. The breast CT application lends itself to CBCT because of the small dimensions of the breast, the tapered shape of the breast towards higher cone angle, and the fact that there are no bones in the breast. The performance of various generations of breast CT scanners developed in recent years will be discussed, focusing on advances in spatial resolution and image noise characteristics. The results will also demonstrate the results of clinical trials using both computer and human observers. Learning Objectives: Understand the challenges, key technological advances, and emerging opportunities of CBCT in: Brain perfusion imaging, including assessment of ischemic stroke Cardiac imaging for functional assessment in cardiac interventions Orthopedics imaging for evaluation of musculoskeletal trauma, arthritis, and osteoporosis Breast imaging for screening and diagnosis of breast cancer. Work presented in this symposium includes research support by: Siemens Healthcare (Dr. Chen); NIH and Siemens Healthcare (Dr. Fahrig); NIH and Carestream Health (Dr. Zbijewski); and NIH (Dr. Boone)« less

TU-AB-204-00: Advances in Cone-Beam CT and Emerging Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both themore » likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions, significant effort has been expended to improve the quantitative accuracy of C-arm CBCT reconstructions. The challenge is to improve image quality while providing very short turnaround between data acquisition and volume data visualization. Corrections for x-ray scatter, view aliasing and patient motion that require no more than 2 iterations keep processing time short while reducing artifact. Fast, multi-sweep acquisitions can be used to permit assessment of left ventricular function, and visualization of radiofrequency lesions created to treat arrhythmias. Workflows for each imaging goal have been developed and validated against gold standard clinical CT or histology. The challenges, opportunities, and limitations of the new functional C-arm CBCT imaging techniques will be discussed. Dr. W. Zbijewski (Johns Hopkins University) will present on the topic: Advances in CBCT for Orthopaedics and Bone Health Imaging. Cone-beam CT is particularly well suited for imaging of musculoskeletal extremities. Owing to the high spatial resolution of flat-panel detectors, CBCT can surpass conventional CT in imaging tasks involving bone visualization, quantitative analysis of subchondral trabecular structure, and visualization and monitoring of subtle fractures that are common in orthopedic radiology. A dedicated CBCT platform has been developed that offers flexibility in system design and provides not only a compact configuration with improved logistics for extremities imaging but also enables novel diagnostic capabilities such as imaging of weight-bearing lower extremities in a natural stance. The design, development and clinical performance of dedicated extremities CBCT systems will be presented. Advanced capabilities for quantitative volumetric assessment of joint space morphology, dual-energy image-based quantification of bone composition, and in-vivo analysis of bone microarchitecture will be discussed, along with emerging applications in the diagnosis of arthritis and osteoporosis and assessment of novel therapies. Finally, Dr. J. Boone (UC Davis) will present on the topic: Advances in CBCT for Breast Imaging. Breast CT has been studied as an imaging tool for diagnostic breast evaluation and for potential breast cancer screening. The breast CT application lends itself to CBCT because of the small dimensions of the breast, the tapered shape of the breast towards higher cone angle, and the fact that there are no bones in the breast. The performance of various generations of breast CT scanners developed in recent years will be discussed, focusing on advances in spatial resolution and image noise characteristics. The results will also demonstrate the results of clinical trials using both computer and human observers. Learning Objectives: Understand the challenges, key technological advances, and emerging opportunities of CBCT in: Brain perfusion imaging, including assessment of ischemic stroke Cardiac imaging for functional assessment in cardiac interventions Orthopedics imaging for evaluation of musculoskeletal trauma, arthritis, and osteoporosis Breast imaging for screening and diagnosis of breast cancer. Work presented in this symposium includes research support by: Siemens Healthcare (Dr. Chen); NIH and Siemens Healthcare (Dr. Fahrig); NIH and Carestream Health (Dr. Zbijewski); and NIH (Dr. Boone)« less

TU-AB-204-01: Advances in C-Arm CBCT for Brain Perfusion Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, G.

This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both themore » likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions, significant effort has been expended to improve the quantitative accuracy of C-arm CBCT reconstructions. The challenge is to improve image quality while providing very short turnaround between data acquisition and volume data visualization. Corrections for x-ray scatter, view aliasing and patient motion that require no more than 2 iterations keep processing time short while reducing artifact. Fast, multi-sweep acquisitions can be used to permit assessment of left ventricular function, and visualization of radiofrequency lesions created to treat arrhythmias. Workflows for each imaging goal have been developed and validated against gold standard clinical CT or histology. The challenges, opportunities, and limitations of the new functional C-arm CBCT imaging techniques will be discussed. Dr. W. Zbijewski (Johns Hopkins University) will present on the topic: Advances in CBCT for Orthopaedics and Bone Health Imaging. Cone-beam CT is particularly well suited for imaging of musculoskeletal extremities. Owing to the high spatial resolution of flat-panel detectors, CBCT can surpass conventional CT in imaging tasks involving bone visualization, quantitative analysis of subchondral trabecular structure, and visualization and monitoring of subtle fractures that are common in orthopedic radiology. A dedicated CBCT platform has been developed that offers flexibility in system design and provides not only a compact configuration with improved logistics for extremities imaging but also enables novel diagnostic capabilities such as imaging of weight-bearing lower extremities in a natural stance. The design, development and clinical performance of dedicated extremities CBCT systems will be presented. Advanced capabilities for quantitative volumetric assessment of joint space morphology, dual-energy image-based quantification of bone composition, and in-vivo analysis of bone microarchitecture will be discussed, along with emerging applications in the diagnosis of arthritis and osteoporosis and assessment of novel therapies. Finally, Dr. J. Boone (UC Davis) will present on the topic: Advances in CBCT for Breast Imaging. Breast CT has been studied as an imaging tool for diagnostic breast evaluation and for potential breast cancer screening. The breast CT application lends itself to CBCT because of the small dimensions of the breast, the tapered shape of the breast towards higher cone angle, and the fact that there are no bones in the breast. The performance of various generations of breast CT scanners developed in recent years will be discussed, focusing on advances in spatial resolution and image noise characteristics. The results will also demonstrate the results of clinical trials using both computer and human observers. Learning Objectives: Understand the challenges, key technological advances, and emerging opportunities of CBCT in: Brain perfusion imaging, including assessment of ischemic stroke Cardiac imaging for functional assessment in cardiac interventions Orthopedics imaging for evaluation of musculoskeletal trauma, arthritis, and osteoporosis Breast imaging for screening and diagnosis of breast cancer. Work presented in this symposium includes research support by: Siemens Healthcare (Dr. Chen); NIH and Siemens Healthcare (Dr. Fahrig); NIH and Carestream Health (Dr. Zbijewski); and NIH (Dr. Boone)« less

TU-AB-204-04: Advances in CBCT for Breast Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boone, J.

This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both themore » likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions, significant effort has been expended to improve the quantitative accuracy of C-arm CBCT reconstructions. The challenge is to improve image quality while providing very short turnaround between data acquisition and volume data visualization. Corrections for x-ray scatter, view aliasing and patient motion that require no more than 2 iterations keep processing time short while reducing artifact. Fast, multi-sweep acquisitions can be used to permit assessment of left ventricular function, and visualization of radiofrequency lesions created to treat arrhythmias. Workflows for each imaging goal have been developed and validated against gold standard clinical CT or histology. The challenges, opportunities, and limitations of the new functional C-arm CBCT imaging techniques will be discussed. Dr. W. Zbijewski (Johns Hopkins University) will present on the topic: Advances in CBCT for Orthopaedics and Bone Health Imaging. Cone-beam CT is particularly well suited for imaging of musculoskeletal extremities. Owing to the high spatial resolution of flat-panel detectors, CBCT can surpass conventional CT in imaging tasks involving bone visualization, quantitative analysis of subchondral trabecular structure, and visualization and monitoring of subtle fractures that are common in orthopedic radiology. A dedicated CBCT platform has been developed that offers flexibility in system design and provides not only a compact configuration with improved logistics for extremities imaging but also enables novel diagnostic capabilities such as imaging of weight-bearing lower extremities in a natural stance. The design, development and clinical performance of dedicated extremities CBCT systems will be presented. Advanced capabilities for quantitative volumetric assessment of joint space morphology, dual-energy image-based quantification of bone composition, and in-vivo analysis of bone microarchitecture will be discussed, along with emerging applications in the diagnosis of arthritis and osteoporosis and assessment of novel therapies. Finally, Dr. J. Boone (UC Davis) will present on the topic: Advances in CBCT for Breast Imaging. Breast CT has been studied as an imaging tool for diagnostic breast evaluation and for potential breast cancer screening. The breast CT application lends itself to CBCT because of the small dimensions of the breast, the tapered shape of the breast towards higher cone angle, and the fact that there are no bones in the breast. The performance of various generations of breast CT scanners developed in recent years will be discussed, focusing on advances in spatial resolution and image noise characteristics. The results will also demonstrate the results of clinical trials using both computer and human observers. Learning Objectives: Understand the challenges, key technological advances, and emerging opportunities of CBCT in: Brain perfusion imaging, including assessment of ischemic stroke Cardiac imaging for functional assessment in cardiac interventions Orthopedics imaging for evaluation of musculoskeletal trauma, arthritis, and osteoporosis Breast imaging for screening and diagnosis of breast cancer. Work presented in this symposium includes research support by: Siemens Healthcare (Dr. Chen); NIH and Siemens Healthcare (Dr. Fahrig); NIH and Carestream Health (Dr. Zbijewski); and NIH (Dr. Boone)« less

Overview and Summary of Advanced UVOIR Mirror Technology Development (AMTD) Project

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2014-01-01

ASTRO2010 Decadal Survey stated that an advanced large-aperture ultraviolet, optical, near-infrared (UVOIR) telescope is required to enable the next generation of compelling astrophysics and exoplanet science; and, that present technology is not mature enough to affordably build and launch any potential UVOIR mission concept. AMTD is a multiyear effort to develop, demonstrate and mature critical technologies to TRL-6 by 2018 so that a viable flight mission can be proposed to the 2020 Decadal Review. AMTD builds on the state of art (SOA) defined by over 30 years of monolithic & segmented ground & space-telescope mirror technology to mature six key technologies: center dotLarge-Aperture, Low Areal Density, High Stiffness Mirror Substrates: Both (4 to 8 m) monolithic and (8 to 16 m) segmented telescopes require larger and stiffer mirrors. center dotSupport System: Large-aperture mirrors require large support systems to ensure that they survive launch, deploy on orbit, and maintain a stable, undistorted shape. center dotMid/High Spatial Frequency Figure Error: Very smooth mirror is critical for producing high-quality point spread function (PSF) for high contrast imaging. center dotSegment Edges: The quality of segment edges impacts PSF for high-contrast imaging applications, contributes to stray light noise, and affects total collecting aperture. center dotSegment to Segment Gap Phasing: Segment phasing is critical for producing high-quality temporally-stable PSF. center dotIntegrated Model Validation: On-orbit performance is driven by mechanical & thermal stability. Compliance cannot be 100% tested, but relies on modeling. Because we cannot predict the future, AMTD is pursuing multiple design paths to provide the science community with options to enable either large aperture monolithic or segmented mirrors with clear engineering metrics traceable to science requirements

Advanced UVOIR Mirror Technology Development (AMTD) for Very Large Space Telescopes

NASA Technical Reports Server (NTRS)

Postman, Marc; Soummer, Remi; Sivramakrishnan, Annand; Macintosh, Bruce; Guyon, Olivier; Krist, John; Stahl, H. Philip; Smith, W. Scott; Mosier, Gary; Kirk, Charles;

SU-E-P-10: Imaging in the Cardiac Catheterization Lab - Technologies and Clinical Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fetterly, K

2014-06-01

Purpose: Diagnosis and treatment of cardiovascular disease in the cardiac catheterization laboratory is often aided by a multitude of imaging technologies. The purpose of this work is to highlight the contributions to patient care offered by the various imaging systems used during cardiovascular interventional procedures. Methods: Imaging technologies used in the cardiac catheterization lab were characterized by their fundamental technology and by the clinical applications for which they are used. Whether the modality is external to the patient, intravascular, or intracavity was specified. Specific clinical procedures for which multiple modalities are routinely used will be highlighted. Results: X-ray imaging modalitiesmore » include fluoroscopy/angiography and angiography CT. Ultrasound imaging is performed with external, trans-esophageal echocardiography (TEE), and intravascular (IVUS) transducers. Intravascular infrared optical coherence tomography (IVOCT) is used to assess vessel endothelium. Relatively large (>0.5 mm) anatomical structures are imaged with x-ray and ultrasound. IVUS and IVOCT provide high resolution images of vessel walls. Cardiac CT and MRI images are used to plan complex cardiovascular interventions. Advanced applications are used to spatially and temporally merge images from different technologies. Diagnosis and treatment of coronary artery disease frequently utilizes angiography and intra-vascular imaging, and treatment of complex structural heart conditions routinely includes use of multiple imaging modalities. Conclusion: There are several imaging modalities which are routinely used in the cardiac catheterization laboratory to diagnose and treat both coronary artery and structural heart disease. Multiple modalities are frequently used to enhance the quality and safety of procedures. The cardiac catheterization laboratory includes many opportunities for medical physicists to contribute substantially toward advancing patient care.« less

Quantifying Neighborhood-Scale Spatial Variations of Ozone at Open Space and Urban Sites in Boulder, Colorado Using Low-Cost Sensor Technology.

PubMed

Cheadle, Lucy; Deanes, Lauren; Sadighi, Kira; Gordon Casey, Joanna; Collier-Oxandale, Ashley; Hannigan, Michael

2017-09-10

Recent advances in air pollution sensors have led to a new wave of low-cost measurement systems that can be deployed in dense networks to capture small-scale spatio-temporal variations in ozone, a pollutant known to cause negative human health impacts. This study deployed a network of seven low-cost ozone metal oxide sensor systems (UPods) in both an open space and an urban location in Boulder, Colorado during June and July of 2015, to quantify ozone variations on spatial scales ranging from 12 m between UPods to 6.7 km between open space and urban measurement sites with a measurement uncertainty of ~5 ppb. The results showed spatial variability of ozone at both deployment sites, with the largest differences between UPod measurements occurring during the afternoons. The peak median hourly difference between UPods was 6 ppb at 1:00 p.m. at the open space site, and 11 ppb at 4:00 p.m. at the urban site. Overall, the urban ozone measurements were higher than in the open space measurements. This study evaluates the effectiveness of using low-cost sensors to capture microscale spatial and temporal variation of ozone; additionally, it highlights the importance of field calibrations and measurement uncertainty quantification when deploying low-cost sensors.

Pairwise graphical models for structural health monitoring with dense sensor arrays

NASA Astrophysics Data System (ADS)

Mohammadi Ghazi, Reza; Chen, Justin G.; Büyüköztürk, Oral

2017-09-01

Through advances in sensor technology and development of camera-based measurement techniques, it has become affordable to obtain high spatial resolution data from structures. Although measured datasets become more informative by increasing the number of sensors, the spatial dependencies between sensor data are increased at the same time. Therefore, appropriate data analysis techniques are needed to handle the inference problem in presence of these dependencies. In this paper, we propose a novel approach that uses graphical models (GM) for considering the spatial dependencies between sensor measurements in dense sensor networks or arrays to improve damage localization accuracy in structural health monitoring (SHM) application. Because there are always unobserved damaged states in this application, the available information is insufficient for learning the GMs. To overcome this challenge, we propose an approximated model that uses the mutual information between sensor measurements to learn the GMs. The study is backed by experimental validation of the method on two test structures. The first is a three-story two-bay steel model structure that is instrumented by MEMS accelerometers. The second experimental setup consists of a plate structure and a video camera to measure the displacement field of the plate. Our results show that considering the spatial dependencies by the proposed algorithm can significantly improve damage localization accuracy.

Application of GPS radio occultation to the assessment of temperature profile retrievals from microwave and infrared sounders

NASA Astrophysics Data System (ADS)

Feltz, M.; Knuteson, R.; Ackerman, S.; Revercomb, H.

2014-05-01

Comparisons of satellite temperature profile products from GPS radio occultation (RO) and hyperspectral infrared (IR)/microwave (MW) sounders are made using a previously developed matchup technique. The profile matchup technique matches GPS RO and IR/MW sounder profiles temporally, within 1 h, and spatially, taking into account the unique RO profile geometry and theoretical spatial resolution by calculating a ray-path averaged sounder profile. The comparisons use the GPS RO dry temperature product. Sounder minus GPS RO differences are computed and used to calculate bias and RMS profile statistics, which are created for global and 30° latitude zones for selected time periods. These statistics are created from various combinations of temperature profile data from the Constellation Observing System for Meteorology, Ionosphere & Climate (COSMIC) network, Global Navigation Satellite System Receiver for Atmospheric Sounding (GRAS) instrument, and the Atmospheric Infrared Sounder (AIRS)/Advanced Microwave Sounding Unit (AMSU), Infrared Atmospheric Sounding Interferometer (IASI)/AMSU, and Crosstrack Infrared Sounder (CrIS)/Advanced Technology Microwave Sounder (ATMS) sounding systems. By overlaying combinations of these matchup statistics for similar time and space domains, comparisons of different sounders' products, sounder product versions, and GPS RO products can be made. The COSMIC GPS RO network has the spatial coverage, time continuity, and stability to provide a common reference for comparison of the sounder profile products. The results of this study demonstrate that GPS RO has potential to act as a common temperature reference and can help facilitate inter-comparison of sounding retrieval methods and also highlight differences among sensor product versions.

Application of GPS radio occultation to the assessment of temperature profile retrievals from microwave and infrared sounders

NASA Astrophysics Data System (ADS)

Feltz, M.; Knuteson, R.; Ackerman, S.; Revercomb, H.

2014-11-01

Comparisons of satellite temperature profile products from GPS radio occultation (RO) and hyperspectral infrared (IR)/microwave (MW) sounders are made using a previously developed matchup technique. The profile matchup technique matches GPS RO and IR/MW sounder profiles temporally, within 1 h, and spatially, taking into account the unique RO profile geometry and theoretical spatial resolution by calculating a ray-path averaged sounder profile. The comparisons use the GPS RO dry temperature product. Sounder minus GPS RO differences are computed and used to calculate bias and rms profile statistics, which are created for global and 30° latitude zones for selected time periods. These statistics are created from various combinations of temperature profile data from the Constellation Observing System for Meteorology, Ionosphere & Climate (COSMIC) network, Global Navigation Satellite System Receiver for Atmospheric Sounding (GRAS) instrument, and the Atmospheric Infrared Sounder (AIRS)/Advanced Microwave Sounding Unit (AMSU), Infrared Atmospheric Sounding Interferometer (IASI)/AMSU, and Crosstrack Infrared Sounder (CrIS)/Advanced Technology Microwave Sounder (ATMS) sounding systems. By overlaying combinations of these matchup statistics for similar time and space domains, comparisons of different sounders' products, sounder product versions, and GPS RO products can be made. The COSMIC GPS RO network has the spatial coverage, time continuity, and stability to provide a common reference for comparison of the sounder profile products. The results of this study demonstrate that GPS RO has potential to act as a common temperature reference and can help facilitate inter-comparison of sounding retrieval methods and also highlight differences among sensor product versions.

Micro-Mini & Nano-Dosimetry & Innovative Technologies in Radiation Therapy (MMND&ITRO2016)

NASA Astrophysics Data System (ADS)

2017-01-01

The biennial MMND (formerly MMD) - IPCT workshops, founded in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC) in 2001, has become an important international multidisciplinary forum for the discussion of advanced dosimetric technology for radiation therapy quality assurance (QA) and space science, as well as advanced technologies for prostate cancer treatment. In more recent years, the interests of participants and the scope of the workshops have extended far beyond prostate cancer treatment alone to include all aspects of radiation therapy, radiation science and technology. We therefore decided to change the name in 2016 to Innovative Technologies in Radiation Oncology (ITRO). MMND ITRO 2016 was held on 26-31 January, 2016 at the beautiful Wrest Point Hotel in Hobart, Tasmania and attracted an outstanding international faculty and nearly 200 delegates from 18 countries (http://mmnditro2016.com/) The MMND 2016 program continued to cover advanced medical physics aspects of IMRT, IGRT, VMAT, SBRT, MRI LINAC, innovative brachytherapy, and synchrotron MRT. The demand for sophisticated real time and high temporal and spatial resolution (down to the submillimetre scale) dosimetry methods and instrumentation for end-to-end QA for these radiotherapy technologies is increasing. Special attention was paid to the contribution of advanced imaging and the application of nanoscience to the recent improvements in imaging and radiotherapy. The last decade has seen great progress in charged particle therapy technology which has spread throughout the world and attracted strong current interest in Australia. This demands a better understanding of the fundamental aspects of ion interactions with biological tissue and the relative biological effectiveness (RBE) of protons and heavy ions. The further development of computational and experimental micro-and nano-dosimetry for ions has important application in radiobiology based treatment planning and space radiation hazard prediction. New compact accelerator technologies for the delivery of proton and heavy ion therapy and relevant QA dosimetry instrumentation were an additional focus of MMND 2016. The ITRO program this year was dedicated to clinical aspects of innovative SBRT for cancer treatment. It represented a unique opportunity to learn from didactic lectures as well as case based discussions with world leaders in the field in the relaxed atmosphere of Hobart. As well as the outstanding scientific program, MMND ITRO 2016 included an Australian beach BBQ to celebrate Australia Day on the evening of 26th January and an exciting social program on 29th January followed by the conference dinner and great Australian hospitality. The MMND workshop represents an important next step for improving current cancer treatments with radiation and the development of new radiation based cancer treatments.

Enabling Technologies for Characterizing Exoplanet Systems with Exo-C

NASA Astrophysics Data System (ADS)

Cahoy, Kerri Lynn; Belikov, Ruslan; Stapelfeldt, Karl R.; Chakrabarti, Supriya; Trauger, John T.; Serabyn, Eugene; McElwain, Michael W.; Pong, Christopher M.; Brugarolas, Paul

2015-01-01

The Exoplanet Science and Technology Definition Team's Internal Coronagraph mission design, called 'Exo-C', utilizes several technologies that have advanced over the past decade with support from the Exoplanet Exploration Program. Following the flow of photons through the telescope, the science measurement is enabled by (i) a precision pointing system to keep the target exoplanet system precisely positioned on the detector during the integration time, (ii) high-performance coronagraphs to block the parent star's light so that the planet's reflected light can be detected, (iii) a wavefront control system to compensate for any wavefront errors such as those due to thermal or mechanical deformations in the optical path, especially errors with high spatial frequencies that could cause contrast-reducing speckles, and (iv) an integral field spectrograph (IFS) that provides moderate resolution spectra of the target exoplanets, permitting their characterization and comparison with models and other data sets. Technologies such as the wavefront control system and coronagraphs will also benefit from other funded efforts in progress, such as the Wide Field Infrared Survey Telescope Astrophysics Focused Telescope Assets (WFIRST-AFTA) program. Similarly, the Exo-C IFS will benefit from the Prototype Imaging Spectrograph for Coronagraphic Exoplanet Studies (PISCES) demonstration. We present specific examples for each of these technologies showing that the state of the art has advanced to levels that will meet the overall scientific, cost, and schedule requirements of the Exo-C mission. These capabilities have matured with testbed and/or ground-telescope demonstrations and have reached a technological readiness level (TRL) that supports their inclusion in the baseline design for potential flight at the end of this decade. While additional work remains to build and test flight-like components (that concurrently meet science as well as size, weight, power, and environmental requirements) and to integrate these subsystems together for a hardware-in-the-loop end-to-end demonstration, the overall readiness of the suite of enabling technologies makes a compelling case for Exo-C among the exoplanet direct imaging mission candidates.

System design analyses of a rotating advanced-technology space station for the year 2025

NASA Technical Reports Server (NTRS)

Queijo, M. J.; Butterfield, A. J.; Cuddihy, W. F.; Stone, R. W.; Wrobel, J. R.; Garn, P. A.; King, C. B.

1988-01-01

Studies of an advanced technology space station configured to implement subsystem technologies projected for availability in the time period 2000 to 2025 is documented. These studies have examined the practical synergies in operational performance available through subsystem technology selection and identified the needs for technology development. Further analyses are performed on power system alternates, momentum management and stabilization, electrothermal propulsion, composite materials and structures, launch vehicle alternates, and lunar and planetary missions. Concluding remarks are made regarding the advanced technology space station concept, its intersubsystem synergies, and its system operational subsystem advanced technology development needs.

76 FR 47641 - Pagani Automobili SpA; Denial of Application for Temporary Exemption From Advanced Air Bag...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... regarding the availability of advanced air bag technology. Docket Nos. NHTSA-2011-0030-0006, NHTSA-2011-0006... advanced air bag technology.\\9\\ Accordingly, NHTSA concludes that the expense of advanced air bag... belief that advanced air bag technology has become more accessible to small volume manufacturers in...

Application of Microfluidics in Experimental Ecology: The Importance of Being Spatial.

PubMed

Nagy, Krisztina; Ábrahám, Ágnes; Keymer, Juan E; Galajda, Péter

2018-01-01

Microfluidics is an emerging technology that is used more and more in biology experiments. Its capabilities of creating precisely controlled conditions in cellular dimensions make it ideal to explore cell-cell and cell-environment interactions. Thus, a wide spectrum of problems in microbial ecology can be studied using engineered microbial habitats. Moreover, artificial microfluidic ecosystems can serve as model systems to test ecology theories and principles that apply on a higher level in the hierarchy of biological organization. In this mini review we aim to demonstrate the versatility of microfluidics and the diversity of its applications that help the advance of microbiology, and in more general, experimental ecology.

Multisensory Rehabilitation Training Improves Spatial Perception in Totally but Not Partially Visually Deprived Children

PubMed Central

Cappagli, Giulia; Finocchietti, Sara; Baud-Bovy, Gabriel; Cocchi, Elena; Gori, Monica

2017-01-01

Since it has been shown that spatial development can be delayed in blind children, focused sensorimotor trainings that associate auditory and motor information might be used to prevent the risk of spatial-related developmental delays or impairments from an early age. With this aim, we proposed a new technological device based on the implicit link between action and perception: ABBI (Audio Bracelet for Blind Interaction) is an audio bracelet that produces a sound when a movement occurs by allowing the substitution of the visuo-motor association with a new audio-motor association. In this study, we assessed the effects of an extensive but entertaining sensorimotor training with ABBI on the development of spatial hearing in a group of seven 3–5 years old children with congenital blindness (n = 2; light perception or no perception of light) or low vision (n = 5; visual acuity range 1.1–1.7 LogMAR). The training required the participants to play several spatial games individually and/or together with the psychomotor therapist 1 h per week for 3 months: the spatial games consisted of exercises meant to train their ability to associate visual and motor-related signals from their body, in order to foster the development of multisensory processes. We measured spatial performance by asking participants to indicate the position of one single fixed (static condition) or moving (dynamic condition) sound source on a vertical sensorized surface. We found that spatial performance of congenitally blind but not low vision children is improved after the training, indicating that early interventions with the use of science-driven devices based on multisensory capabilities can provide consistent advancements in therapeutic interventions, improving the quality of life of children with visual disability. PMID:29097987

Thin Mirror Shaping Technology for High-Throughput X-ray Telescopes

NASA Astrophysics Data System (ADS)

Schattenburg, Mark

This proposal is submitted to the NASA Research Opportunities in Space and Earth Sciences program (ROSES-2012) in response to NASA Research Announcement NNH12ZDA001N- APRA. It is targeted to the Astronomy and Astrophysics Research and Analysis (APRA) program element under the Supporting Technology category. Powerful x-ray telescope mirrors are critical components of a raft of small-to-large mission concepts under consideration by NASA. The science questions addressed by these missions have certainly never been more compelling and the need to fulfill NASA s core missions of exploring the universe and strengthening our nation s technology base has never been greater. Unfortunately, budgetary constraints are driving NASA to consider the cost/benefit and risk factors of new missions more carefully than ever. New technology for producing x-ray telescopes with increased resolution and collecting area, while holding down cost, are key to meeting these goals and sustaining a thriving high-energy astrophysics enterprise in the US. We propose to develop advanced technology which will lead to thin-shell x-ray telescope mirrors rivaling the Chandra x-ray telescope in spatial resolution but with 10-100X larger area all at significantly reduced weight, risk and cost. The proposed effort builds on previous research at MIT and complements NASA-supported research at other institutions. We are currently pursuing two thin-mirror technology development tracks which we propose to extend and accelerate with NASA support. The first research track utilizes rapidly-maturing thermal glass slumping technology which uses porous ceramic air-bearing mandrels to shape glass mirrors without touching, thus avoiding surface-induced mid-range spatial frequency ripples. A second research track seeks to remove any remaining mid- to long-range errors in mirrors by using scanning ion-beam implant to impart small, highly deterministic and very stable amounts of stress into thin glass, utilizing local bending moments to correct mirror shape. Preliminary results from our lab demonstrate the simplicity, specificity, and exquisite sensitivity of this technique on silicon and glass wafers. We believe that the combination of these new technologies has the potential to revolutionize thin mirror shaping technology and will enable a renaissance in high-energy astrophysics.

Regulations in the field of Geo-Information

NASA Astrophysics Data System (ADS)

Felus, Y.; Keinan, E.; Regev, R.

2013-10-01

The geomatics profession has gone through a major revolution during the last two decades with the emergence of advanced GNSS, GIS and Remote Sensing technologies. These technologies have changed the core principles and working procedures of geomatics professionals. For this reason, surveying and mapping regulations, standards and specifications should be updated to reflect these changes. In Israel, the "Survey Regulations" is the principal document that regulates the professional activities in four key areas geodetic control, mapping, cadastre and Georaphic information systems. Licensed Surveyors and mapping professionals in Israel are required to work according to those regulations. This year a new set of regulations have been published and include a few major amendments as follows: In the Geodesy chapter, horizontal control is officially based on the Israeli network of Continuously Operating GNSS Reference Stations (CORS). The regulations were phrased in a manner that will allow minor datum changes to the CORS stations due to Earth Crustal Movements. Moreover, the regulations permit the use of GNSS for low accuracy height measurements. In the Cadastre chapter, the most critical change is the move to Coordinate Based Cadastre (CBC). Each parcel corner point is ranked according to its quality (accuracy and clarity of definition). The highest ranking for a parcel corner is 1. A point with a rank of 1 is defined by its coordinates alone. Any other contradicting evidence is inferior to the coordinates values. Cadastral Information is stored and managed via the National Cadastral Databases. In the Mapping and GIS chapter; the traditional paper maps (ranked by scale) are replaced by digital maps or spatial databases. These spatial databases are ranked by their quality level. Quality level is determined (similar to the ISO19157 Standard) by logical consistency, completeness, positional accuracy, attribute accuracy, temporal accuracy and usability. Metadata is another critical component of any spatial database. Every component in a map should have a metadata identification, even if the map was compiled from multiple resources. The regulations permit the use of advanced sensors and mapping techniques including LIDAR and digita l cameras that have been certified and meet the defined criteria. The article reviews these new regulations and the decision that led to them.

1990 fuel cell seminar: Program and abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-12-31

This volume contains author prepared short resumes of the presentations at the 1990 Fuel Cell Seminar held November 25-28, 1990 in Phoenix, Arizona. Contained herein are 134 short descriptions organized into topic areas entitled An Environmental Overview, Transportation Applications, Technology Advancements for Molten Carbonate Fuel Cells, Technology Advancements for Solid Fuel Cells, Component Technologies and Systems Analysis, Stationary Power Applications, Marine and Space Applications, Technology Advancements for Acid Type Fuel Cells, and Technology Advancement for Solid Oxide Fuel Cells.

Spatial Thinking Assists Geographic Thinking: Evidence from a Study Exploring the Effects of Geospatial Technology

ERIC Educational Resources Information Center

Metoyer, Sandra; Bednarz, Robert

2017-01-01

This article provides a description and discussion of an exploratory research study that examined the effects of using geospatial technology (GST) on high school students' spatial skills and spatial-relations content knowledge. It presents results that support the use of GST to teach spatially dependent content. It also provides indication of an…

First-order error budgeting for LUVOIR mission

NASA Astrophysics Data System (ADS)

Lightsey, Paul A.; Knight, J. Scott; Feinberg, Lee D.; Bolcar, Matthew R.; Shaklan, Stuart B.

2017-09-01

Future large astronomical telescopes in space will have architectures that will have complex and demanding requirements to meet the science goals. The Large UV/Optical/IR Surveyor (LUVOIR) mission concept being assessed by the NASA/Goddard Space Flight Center is expected to be 9 to 15 meters in diameter, have a segmented primary mirror and be diffraction limited at a wavelength of 500 nanometers. The optical stability is expected to be in the picometer range for minutes to hours. Architecture studies to support the NASA Science and Technology Definition teams (STDTs) are underway to evaluate systems performance improvements to meet the science goals. To help define the technology needs and assess performance, a first order error budget has been developed. Like the JWST error budget, the error budget includes the active, adaptive and passive elements in spatial and temporal domains. JWST performance is scaled using first order approximations where appropriate and includes technical advances in telescope control.

Molecular cartography of the human skin surface in 3D.

PubMed

Bouslimani, Amina; Porto, Carla; Rath, Christopher M; Wang, Mingxun; Guo, Yurong; Gonzalez, Antonio; Berg-Lyon, Donna; Ackermann, Gail; Moeller Christensen, Gitte Julie; Nakatsuji, Teruaki; Zhang, Lingjuan; Borkowski, Andrew W; Meehan, Michael J; Dorrestein, Kathleen; Gallo, Richard L; Bandeira, Nuno; Knight, Rob; Alexandrov, Theodore; Dorrestein, Pieter C

2015-04-28

The human skin is an organ with a surface area of 1.5-2 m(2) that provides our interface with the environment. The molecular composition of this organ is derived from host cells, microbiota, and external molecules. The chemical makeup of the skin surface is largely undefined. Here we advance the technologies needed to explore the topographical distribution of skin molecules, using 3D mapping of mass spectrometry data and microbial 16S rRNA amplicon sequences. Our 3D maps reveal that the molecular composition of skin has diverse distributions and that the composition is defined not only by skin cells and microbes but also by our daily routines, including the application of hygiene products. The technological development of these maps lays a foundation for studying the spatial relationships of human skin with hygiene, the microbiota, and environment, with potential for developing predictive models of skin phenotypes tailored to individual health.

Molecular cartography of the human skin surface in 3D

PubMed Central

Bouslimani, Amina; Porto, Carla; Rath, Christopher M.; Wang, Mingxun; Guo, Yurong; Gonzalez, Antonio; Berg-Lyon, Donna; Ackermann, Gail; Moeller Christensen, Gitte Julie; Nakatsuji, Teruaki; Zhang, Lingjuan; Borkowski, Andrew W.; Meehan, Michael J.; Dorrestein, Kathleen; Gallo, Richard L.; Bandeira, Nuno; Knight, Rob; Alexandrov, Theodore; Dorrestein, Pieter C.

2015-01-01

The human skin is an organ with a surface area of 1.5–2 m2 that provides our interface with the environment. The molecular composition of this organ is derived from host cells, microbiota, and external molecules. The chemical makeup of the skin surface is largely undefined. Here we advance the technologies needed to explore the topographical distribution of skin molecules, using 3D mapping of mass spectrometry data and microbial 16S rRNA amplicon sequences. Our 3D maps reveal that the molecular composition of skin has diverse distributions and that the composition is defined not only by skin cells and microbes but also by our daily routines, including the application of hygiene products. The technological development of these maps lays a foundation for studying the spatial relationships of human skin with hygiene, the microbiota, and environment, with potential for developing predictive models of skin phenotypes tailored to individual health. PMID:25825778

Display challenges resulting from the use of wide field of view imaging devices

NASA Astrophysics Data System (ADS)

Petty, Gregory J.; Fulton, Jack; Nicholson, Gail; Seals, Ean

2012-06-01

As focal plane array technologies advance and imagers increase in resolution, display technology must outpace the imaging improvements in order to adequately represent the complete data collection. Typical display devices tend to have an aspect ratio similar to 4:3 or 16:9, however a breed of Wide Field of View (WFOV) imaging devices exist that skew from the norm with aspect ratios as high as 5:1. This particular quality, when coupled with a high spatial resolution, presents a unique challenge for display devices. Standard display devices must choose between resizing the image data to fit the display and displaying the image data in native resolution and truncating potentially important information. The problem compounds when considering the applications; WFOV high-situationalawareness imagers are sought for space-limited military vehicles. Tradeoffs between these issues are assessed to the image quality of the WFOV sensor.

Design & implementation of distributed spatial computing node based on WPS

NASA Astrophysics Data System (ADS)

Liu, Liping; Li, Guoqing; Xie, Jibo

2014-03-01

Currently, the research work of SIG (Spatial Information Grid) technology mostly emphasizes on the spatial data sharing in grid environment, while the importance of spatial computing resources is ignored. In order to implement the sharing and cooperation of spatial computing resources in grid environment, this paper does a systematical research of the key technologies to construct Spatial Computing Node based on the WPS (Web Processing Service) specification by OGC (Open Geospatial Consortium). And a framework of Spatial Computing Node is designed according to the features of spatial computing resources. Finally, a prototype of Spatial Computing Node is implemented and the relevant verification work under the environment is completed.

A CMOS-based large-area high-resolution imaging system for high-energy x-ray applications

NASA Astrophysics Data System (ADS)

Rodricks, Brian; Fowler, Boyd; Liu, Chiao; Lowes, John; Haeffner, Dean; Lienert, Ulrich; Almer, John

2008-08-01

CCDs have been the primary sensor in imaging systems for x-ray diffraction and imaging applications in recent years. CCDs have met the fundamental requirements of low noise, high-sensitivity, high dynamic range and spatial resolution necessary for these scientific applications. State-of-the-art CMOS image sensor (CIS) technology has experienced dramatic improvements recently and their performance is rivaling or surpassing that of most CCDs. The advancement of CIS technology is at an ever-accelerating pace and is driven by the multi-billion dollar consumer market. There are several advantages of CIS over traditional CCDs and other solid-state imaging devices; they include low power, high-speed operation, system-on-chip integration and lower manufacturing costs. The combination of superior imaging performance and system advantages makes CIS a good candidate for high-sensitivity imaging system development. This paper will describe a 1344 x 1212 CIS imaging system with a 19.5μm pitch optimized for x-ray scattering studies at high-energies. Fundamental metrics of linearity, dynamic range, spatial resolution, conversion gain, sensitivity are estimated. The Detective Quantum Efficiency (DQE) is also estimated. Representative x-ray diffraction images are presented. Diffraction images are compared against a CCD-based imaging system.

Assessing Unilateral Spatial Neglect using advanced technologies: The potentiality of mobile virtual reality.

PubMed

Pallavicini, Federica; Pedroli, Elisa; Serino, Silvia; Dell'Isola, Andrea; Cipresso, Pietro; Cisari, Carlo; Riva, Giuseppe

2015-01-01

Unilateral Spatial Neglect, or neglect, is a common behavioral syndrome in patients following unilateral brain damage, such as stroke. In recent years, new technologies, such as computer-based tools and virtual reality have been used in order to solve some limitations of the traditional neglect evaluation. Within this perspective, also mobile devices such as tablets seems to be promising tools, being able to support interactive virtual environments and, at the same time, allowing to easily reproduce traditional paper-and-pencil test. In this context, the aim of our study was to investigate the potentiality of a new mobile application (Neglect App) designed and developed for tablet (iPad) for screening neglect symptoms. To address this objective, we divided a sample of 16 right-damaged patients according to the presence or absence of neglect and we administered assessment test in their traditional and Neglect App version. Results showed that the cancellation tests developed within Neglect App were equally effective to traditional paper-and-pencil tests (Line cancellation test and Star Cancellation test) in detecting neglect symptoms. Secondly, according to our results, the Neglect App Card Dealing task was more sensitive in detecting neglect symptoms than traditional functional task. Globally, results gives preliminary evidences supporting the feasibility of Neglect App for the screening of USN symptoms.

High Spatial Resolution Thermal Satellite Technologies

NASA Technical Reports Server (NTRS)

Ryan, Robert

2003-01-01

This document in the form of viewslides, reviews various low-cost alternatives to high spatial resolution thermal satellite technologies. There exists no follow-on to Landsat 7 or ASTER high spatial resolution thermal systems. This document reviews the results of the investigation in to the use of new technologies to create a low-cost useful alternative. Three suggested technologies are examined. 1. Conventional microbolometer pushbroom modes offers potential for low cost Landsat Data Continuity Mission (LDCM) thermal or ASTER capability with at least 60-120 ground sampling distance (GSD). 2. Backscanning could produce MultiSpectral Thermal Imager performance without cooled detectors. 3. Cooled detector could produce hyperspectral thermal class system or extremely high spatial resolution class instrument.

Statement of Aaron Cohen, Director, Research and Engineering, Johnson Space Center and Chairman, Space Station Advanced Technology Advisory Committee, National Aeronautics and Space Administration, before the Subcommittee on Science, Technology, and Space, Committee on Commerce, Science, and Transportation, United States Senate

NASA Technical Reports Server (NTRS)

Cohen, A.

1985-01-01

The activities of NASA's Space Station Advanced Technology Advisory Committee is discussed. Advanced Technology Advisory Committee (ATAC) activities over the last year are reviewed in preparation of the report to Congress on the potential for advancing automation and robotics technology for the space station and for the U.S. economy.

Spatial Knowledge Infrastructures - Creating Value for Policy Makers and Benefits the Community

NASA Astrophysics Data System (ADS)

Arnold, L. M.

2016-12-01

The spatial data infrastructure is arguably one of the most significant advancements in the spatial sector. It's been a game changer for governments, providing for the coordination and sharing of spatial data across organisations and the provision of accessible information to the broader community of users. Today however, end-users such as policy-makers require far more from these spatial data infrastructures. They want more than just data; they want the knowledge that can be extracted from data and they don't want to have to download, manipulate and process data in order to get the knowledge they seek. It's time for the spatial sector to reduce its focus on data in spatial data infrastructures and take a more proactive step in emphasising and delivering the knowledge value. Nowadays, decision-makers want to be able to query at will the data to meet their immediate need for knowledge. This is a new value proposal for the decision-making consumer and will require a shift in thinking. This paper presents a model for a Spatial Knowledge Infrastructure and underpinning methods that will realise a new real-time approach to delivering knowledge. The methods embrace the new capabilities afforded through the sematic web, domain and process ontologies and natural query language processing. Semantic Web technologies today have the potential to transform the spatial industry into more than just a distribution channel for data. The Semantic Web RDF (Resource Description Framework) enables meaning to be drawn from data automatically. While pushing data out to end-users will remain a central role for data producers, the power of the semantic web is that end-users have the ability to marshal a broad range of spatial resources via a query to extract knowledge from available data. This can be done without actually having to configure systems specifically for the end-user. All data producers need do is make data accessible in RDF and the spatial analytics does the rest.

Using spatial information technologies as monitoring devices in international watershed conservation along the Senegal River Basin of West Africa.

PubMed

Merem, Edmund C; Twumasi, Yaw A

2008-12-01

In this paper, we present the applications of spatial technologies-Geographic Information Systems (GIS) and remote sensing-in the international monitoring of river basins particularly analyzing the ecological, hydrological, and socio-economic issues along the Senegal River. The literature on multinational water crisis has for decades focused on mediation aspects of trans-boundary watershed management resulting in limited emphasis placed on the application of advances in geo-spatial information technologies in multinational watershed conservation in the arid areas of the West African sub-region within the Senegal River Basin for decision-making and monitoring. While the basin offers life support in a complex ecosystem that stretches across different nations in a mostly desert region characterized by water scarcity and subsistence economies, there exists recurrent environmental stress induced by both socio-economic and physical factors. Part of the problems consists of flooding, drought and limited access to sufficient quantities of water. These remain particularly sensitive issues that are crucial for the health of a rapidly growing population and the economy. The problems are further compounded due to the threats of climate change and the resultant degradation of almost the region's entire natural resources base. While the pace at which the institutional framework for managing the waters offers opportunities for hydro electricity and irrigated agriculture through the proliferation of dams, it has raised other serious concerns in the region. Even where data exists for confronting these issues, some of them are incompatible and dispersed among different agencies. This not only widens the geo-spatial data gaps, but it hinders the ability to monitor water problems along the basin. This study will fill that gap in research through mix scale methods built on descriptive statistics, GIS and remote sensing techniques by generating spatially referenced data to supplement the existing ones for the management of the Senegal River Basin. The results show the incidence of change predicated on pressures from demography, natural forces and the proliferation of river basin development which resulted in more irrigated areas to meet the needs of the inhabitants of the basin. With the substantial increase in bare surface areas, the basin faces growing exposure to the threats of desertification.

Industrialization study, phase 2. [assessment of advanced photovoltaic technologies for commerical development

NASA Technical Reports Server (NTRS)

1979-01-01

The potentials and requirements of advanced photovoltaic technologies still in their early developmental stages were evaluated and compared to the present day single crystal silicon wafer technology and to each other. The major areas of consideration include polycrystalline and amorphous silicon, single crystal and polycrystalline gallium arsenide, and single crystal and polycrystalline cadmium sulfide. A rank ordering of the advanced technologies is provided. The various ranking schemes were based upon present-day efficiency levels, their stability and long-term reliability prospects, material availability, capital investments both at the laboratory and production level, and associated variable costs. An estimate of the timing of the possible readiness of these advanced technologies for technology development programs and industrialization is presented along with a set of recommended government actions concerning the various advanced technologies.

Advanced Education and Technology Business Plan, 2010-13. Highlights

ERIC Educational Resources Information Center

Alberta Advanced Education and Technology, 2010

2010-01-01

The Ministry of Advanced Education and Technology envisions Alberta's prosperity through innovation and lifelong learning. Advanced Education and Technology's mission is to lead the development of a knowledge-driven future through a dynamic and integrated advanced learning and innovation system. This paper presents the highlights of the business…

40 CFR 1037.615 - Hybrid vehicles and other advanced technologies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... technologies. 1037.615 Section 1037.615 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Provisions § 1037.615 Hybrid vehicles and other advanced technologies. (a) This section applies for hybrid... credits under 40 CFR part 1036. (b) Generate advanced technology emission credits for hybrid vehicles that...

Statistical metrology—measurement and modeling of variation for advanced process development and design rule generation

NASA Astrophysics Data System (ADS)

Boning, Duane S.; Chung, James E.

1998-11-01

Advanced process technology will require more detailed understanding and tighter control of variation in devices and interconnects. The purpose of statistical metrology is to provide methods to measure and characterize variation, to model systematic and random components of that variation, and to understand the impact of variation on both yield and performance of advanced circuits. Of particular concern are spatial or pattern-dependencies within individual chips; such systematic variation within the chip can have a much larger impact on performance than wafer-level random variation. Statistical metrology methods will play an important role in the creation of design rules for advanced technologies. For example, a key issue in multilayer interconnect is the uniformity of interlevel dielectric (ILD) thickness within the chip. For the case of ILD thickness, we describe phases of statistical metrology development and application to understanding and modeling thickness variation arising from chemical-mechanical polishing (CMP). These phases include screening experiments including design of test structures and test masks to gather electrical or optical data, techniques for statistical decomposition and analysis of the data, and approaches to calibrating empirical and physical variation models. These models can be integrated with circuit CAD tools to evaluate different process integration or design rule strategies. One focus for the generation of interconnect design rules are guidelines for the use of "dummy fill" or "metal fill" to improve the uniformity of underlying metal density and thus improve the uniformity of oxide thickness within the die. Trade-offs that can be evaluated via statistical metrology include the improvements to uniformity possible versus the effect of increased capacitance due to additional metal.

Analysis and Cost Optimization of a USCG Remote Hybrid Power System

DTIC Science & Technology

2002-06-01

finding a system that can withstand the extreme weather conditions at these two sites is limited. It is recommended that as technology advances the...sites be conducted. 2. Battery Technology There have been significant advances in battery technology during the recent past. As these advancements ...costs associated with advanced technology decrease to more affordable levels to help 98 identify replacement batteries for the VRLA batteries when

Technological Education for the Rural Community (TERC) Project: Technical Mathematics for the Advanced Manufacturing Technician

ERIC Educational Resources Information Center

McCormack, Sherry L.; Zieman, Stuart

2017-01-01

Hopkinsville Community College's Technological Education for the Rural Community (TERC) project is funded through the National Science Foundation Advanced Technological Education (NSF ATE) division. It is advancing innovative educational pathways for technological education promoted at the community college level serving rural communities to fill…

42 CFR 495.336 - Health information technology planning advance planning document requirements (HIT PAPD).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 5 2011-10-01 2011-10-01 false Health information technology planning advance... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.336 Health information technology planning advance planning document requirements...

42 CFR 495.336 - Health information technology planning advance planning document requirements (HIT PAPD).

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 5 2013-10-01 2013-10-01 false Health information technology planning advance... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.336 Health information technology planning advance planning document requirements...

42 CFR 495.336 - Health information technology planning advance planning document requirements (HIT PAPD).

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 5 2012-10-01 2012-10-01 false Health information technology planning advance... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.336 Health information technology planning advance planning document requirements...

42 CFR 495.336 - Health information technology planning advance planning document requirements (HIT PAPD).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 5 2014-10-01 2014-10-01 false Health information technology planning advance... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.336 Health information technology planning advance planning document requirements...

42 CFR 495.336 - Health information technology planning advance planning document requirements (HIT PAPD).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Health information technology planning advance... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.336 Health information technology planning advance planning document requirements...

Final Report of the Advanced Coal Technology Work Group

EPA Pesticide Factsheets

The Advanced Coal Technology workgroup reported to the Clean Air Act Advisory Committee. This page includes the final report of the Advanced Coal Technology Work Group to the Clean Air Act Advisory Committee.

Social and private benefits of assisted reproductive technology: a national survey-based evaluation in Israel.

PubMed

Gonen, Limor Dina

2016-01-01

The objective of this paper was to measure the private and social benefits resulting from technological advances in fertility treatment. An empirical model investigates the willingness-to-pay (WTP) for advances in the medical technology of in vitro fertilization (IVF) among the general public and among IVF patients in Israel. The empirical model's findings demonstrate that IVF patients and the general public value medical technology advances and have a positive WTP for it. The average WTP for IVF technology advances, among IVF patients, is US $3116.9 whereas for the general public it is US$2284.4. Available evidence suggests that advances in medical technology have delivered substantial benefits and appear to have contributed to improved wellbeing.

Advanced cogeneration research study: Executive summary

NASA Technical Reports Server (NTRS)

Bluhm, S. A.; Moore, N.; Rosenberg, L.; Slonski, M.

1983-01-01

This study provides a broad based overview of selected areas relevant to the development of a comprehensive Southern California Edison (SCE) advanced cogeneration project. The areas studied are: (1) Cogeneration potential in the SCE service territory; (2) Advanced cogeneration technologies; and (3) Existing cogeneration computer models. An estimated 3700 MW sub E could potentially be generated from existing industries in the Southern California Edison service territory using cogeneration technology. Of this total, current technology could provide 2600 MW sub E and advanced technology could provide 1100 MW sub E. The manufacturing sector (SIC Codes 20-39) was found to have the highest average potential for current cogeneration technology. The mining sector (SIC Codes 10-14) was found to have the highest potential for advanced technology.

The use of geospatial technologies to increase students' spatial abilities and knowledge of certain atmospheric science content

NASA Astrophysics Data System (ADS)

Hedley, Mikell Lynne

2008-10-01

The purpose of the study was to use geospatial technologies to improve the spatial abilities and specific atmospheric science content knowledge of students in high schools and junior highs in primarily high-needs schools. These technologies include remote sensing, geographic information systems, and global positioning systems. The program involved training the teachers in the use of the technologies at a five-day institute. Scientists who use the technologies in their research taught the basics of their use and scientific background. Standards-based activities were used to integrate the technologies in the classroom setting. Students were tested before any instruction in the technologies and then tested two other times. They used the technologies in field data collection and used that data in an inquiry-based project. Their projects were presented at a mini-science conference with scientists, teachers, parents, and other students in attendance. Significant differences were noted from pre-test to second post-test in the test in both the spatial abilities and science section. There was a gain in both spatial abilities and in specific atmospheric science content knowledge.

3D Visualization Development of SIUE Campus

NASA Astrophysics Data System (ADS)

Nellutla, Shravya

Geographic Information Systems (GIS) has progressed from the traditional map-making to the modern technology where the information can be created, edited, managed and analyzed. Like any other models, maps are simplified representations of real world. Hence visualization plays an essential role in the applications of GIS. The use of sophisticated visualization tools and methods, especially three dimensional (3D) modeling, has been rising considerably due to the advancement of technology. There are currently many off-the-shelf technologies available in the market to build 3D GIS models. One of the objectives of this research was to examine the available ArcGIS and its extensions for 3D modeling and visualization and use them to depict a real world scenario. Furthermore, with the advent of the web, a platform for accessing and sharing spatial information on the Internet, it is possible to generate interactive online maps. Integrating Internet capacity with GIS functionality redefines the process of sharing and processing the spatial information. Enabling a 3D map online requires off-the-shelf GIS software, 3D model builders, web server, web applications and client server technologies. Such environments are either complicated or expensive because of the amount of hardware and software involved. Therefore, the second objective of this research was to investigate and develop simpler yet cost-effective 3D modeling approach that uses available ArcGIS suite products and the free 3D computer graphics software for designing 3D world scenes. Both ArcGIS Explorer and ArcGIS Online will be used to demonstrate the way of sharing and distributing 3D geographic information on the Internet. A case study of the development of 3D campus for the Southern Illinois University Edwardsville is demonstrated.

3D Visualization of Urban Area Using Lidar Technology and CityGML

NASA Astrophysics Data System (ADS)

Popovic, Dragana; Govedarica, Miro; Jovanovic, Dusan; Radulovic, Aleksandra; Simeunovic, Vlado

2017-12-01

3D models of urban areas have found use in modern world such as navigation, cartography, urban planning visualization, construction, tourism and even in new applications of mobile navigations. With the advancement of technology there are much better solutions for mapping earth’s surface and spatial objects. 3D city model enables exploration, analysis, management tasks and presentation of a city. Urban areas consist of terrain surfaces, buildings, vegetation and other parts of city infrastructure such as city furniture. Nowadays there are a lot of different methods for collecting, processing and publishing 3D models of area of interest. LIDAR technology is one of the most effective methods for collecting data due the large amount data that can be obtained with high density and geometrical accuracy. CityGML is open standard data model for storing alphanumeric and geometry attributes of city. There are 5 levels of display (LoD0, LoD1, LoD2, LoD3, LoD4). In this study, main aim is to represent part of urban area of Novi Sad using LIDAR technology, for data collecting, and different methods for extraction of information’s using CityGML as a standard for 3D representation. By using series of programs, it is possible to process collected data, transform it to CityGML and store it in spatial database. Final product is CityGML 3D model which can display textures and colours in order to give a better insight of the cities. This paper shows results of the first three levels of display. They consist of digital terrain model and buildings with differentiated rooftops and differentiated boundary surfaces. Complete model gives us a realistic view of 3D objects.

CMEIAS color segmentation: an improved computing technology to process color images for quantitative microbial ecology studies at single-cell resolution.

PubMed

Gross, Colin A; Reddy, Chandan K; Dazzo, Frank B

2010-02-01

Quantitative microscopy and digital image analysis are underutilized in microbial ecology largely because of the laborious task to segment foreground object pixels from background, especially in complex color micrographs of environmental samples. In this paper, we describe an improved computing technology developed to alleviate this limitation. The system's uniqueness is its ability to edit digital images accurately when presented with the difficult yet commonplace challenge of removing background pixels whose three-dimensional color space overlaps the range that defines foreground objects. Image segmentation is accomplished by utilizing algorithms that address color and spatial relationships of user-selected foreground object pixels. Performance of the color segmentation algorithm evaluated on 26 complex micrographs at single pixel resolution had an overall pixel classification accuracy of 99+%. Several applications illustrate how this improved computing technology can successfully resolve numerous challenges of complex color segmentation in order to produce images from which quantitative information can be accurately extracted, thereby gain new perspectives on the in situ ecology of microorganisms. Examples include improvements in the quantitative analysis of (1) microbial abundance and phylotype diversity of single cells classified by their discriminating color within heterogeneous communities, (2) cell viability, (3) spatial relationships and intensity of bacterial gene expression involved in cellular communication between individual cells within rhizoplane biofilms, and (4) biofilm ecophysiology based on ribotype-differentiated radioactive substrate utilization. The stand-alone executable file plus user manual and tutorial images for this color segmentation computing application are freely available at http://cme.msu.edu/cmeias/ . This improved computing technology opens new opportunities of imaging applications where discriminating colors really matter most, thereby strengthening quantitative microscopy-based approaches to advance microbial ecology in situ at individual single-cell resolution.

Application of advanced technologies to small, short-haul transport aircraft

NASA Technical Reports Server (NTRS)

Coussens, T. G.; Tullis, R. H.

1980-01-01

The performance and economic benefits available by incorporation of advanced technologies into the small, short haul air transport were assessed. Low cost structure and advanced composite material, advanced turboprop engines and new propellers, advanced high lift systems and active controls; and alternate aircraft configurations with aft mounted engines were investigated. Improvements in fuel consumed and aircraft economics (acquisition cost and direct operating cost) are available by incorporating selected advanced technologies into the small, short haul aircraft.

GHGs and air pollutants embodied in China’s international trade: Temporal and spatial index decomposition analysis

PubMed Central

Liu, Zhengyan; Mao, Xianqiang; Song, Peng

2017-01-01

Temporal index decomposition analysis and spatial index decomposition analysis were applied to understand the driving forces of the emissions embodied in China’s exports and net exports during 2002–2011, respectively. The accumulated emissions embodied in exports accounted for approximately 30% of the total emissions in China; although the contribution of the sectoral total emissions intensity (technique effect) declined, the scale effect was largely responsible for the mounting emissions associated with export, and the composition effect played a largely insignificant role. Calculations of the emissions embodied in net exports suggest that China is generally in an environmentally inferior position compared with its major trade partners. The differences in the economy-wide emission intensities between China and its major trade partners were the biggest contribution to this reality, and the trade balance effect played a less important role. However, a lower degree of specialization in pollution intensive products in exports than in imports helped to reduce slightly the emissions embodied in net exports. The temporal index decomposition analysis results suggest that China should take effective measures to optimize export and supply-side structure and reduce the total emissions intensity. According to spatial index decomposition analysis, it is suggested that a more aggressive import policy was useful for curbing domestic and global emissions, and the transfer of advanced production technologies and emission control technologies from developed to developing countries should be a compulsory global environmental policy option to mitigate the possible leakage of pollution emissions caused by international trade. PMID:28441399

Advancing automation and robotics technology for the Space Station Freedom and for the US economy

NASA Technical Reports Server (NTRS)

1990-01-01

The progress made by levels 1, 2, and 3 of the Office of Space Station in developing and applying advanced automation and robotics technology is described. Emphasis is placed upon the Space Station Freedom Program responses to specific recommendations made in the Advanced Technology Advisory Committee (ATAC) progress report 10, the flight telerobotic servicer, and the Advanced Development Program. Assessments are presented for these and other areas as they apply to the advancement of automation and robotics technology for the Space Station Freedom.

Spatially disaggregated population estimates in the absence of national population and housing census data

PubMed Central

Wardrop, N. A.; Jochem, W. C.; Bird, T. J.; Chamberlain, H. R.; Clarke, D.; Kerr, D.; Bengtsson, L.; Juran, S.; Seaman, V.; Tatem, A. J.

2018-01-01

Population numbers at local levels are fundamental data for many applications, including the delivery and planning of services, election preparation, and response to disasters. In resource-poor settings, recent and reliable demographic data at subnational scales can often be lacking. National population and housing census data can be outdated, inaccurate, or missing key groups or areas, while registry data are generally lacking or incomplete. Moreover, at local scales accurate boundary data are often limited, and high rates of migration and urban growth make existing data quickly outdated. Here we review past and ongoing work aimed at producing spatially disaggregated local-scale population estimates, and discuss how new technologies are now enabling robust and cost-effective solutions. Recent advances in the availability of detailed satellite imagery, geopositioning tools for field surveys, statistical methods, and computational power are enabling the development and application of approaches that can estimate population distributions at fine spatial scales across entire countries in the absence of census data. We outline the potential of such approaches as well as their limitations, emphasizing the political and operational hurdles for acceptance and sustainable implementation of new approaches, and the continued importance of traditional sources of national statistical data. PMID:29555739

Remote Sensing for Crop Water Management: From ET Modelling to Services for the End Users

PubMed Central

Calera, Alfonso; Campos, Isidro; Osann, Anna; D’Urso, Guido; Menenti, Massimo

2017-01-01

The experiences gathered during the past 30 years support the operational use of irrigation scheduling based on frequent multi-spectral image data. Currently, the operational use of dense time series of multispectral imagery at high spatial resolution makes monitoring of crop biophysical parameters feasible, capturing crop water use across the growing season, with suitable temporal and spatial resolutions. These achievements, and the availability of accurate forecasting of meteorological data, allow for precise predictions of crop water requirements with unprecedented spatial resolution. This information is greatly appreciated by the end users, i.e., professional farmers or decision-makers, and can be provided in an easy-to-use manner and in near-real-time by using the improvements achieved in web-GIS methodologies (Geographic Information Systems based on web technologies). This paper reviews the most operational and explored methods based on optical remote sensing for the assessment of crop water requirements, identifying strengths and weaknesses and proposing alternatives to advance towards full operational application of this methodology. In addition, we provide a general overview of the tools, which facilitates co-creation and collaboration with stakeholders, paying special attention to these approaches based on web-GIS tools. PMID:28492515

Assessment of Completeness and Positional Accuracy of Linear Features in Volunteered Geographic Information (vgi)

NASA Astrophysics Data System (ADS)

Eshghi, M.; Alesheikh, A. A.

2015-12-01

Recent advances in spatial data collection technologies and online services dramatically increase the contribution of ordinary people to produce, share, and use geographic information. Collecting spatial data as well as disseminating them on the internet by citizens has led to a huge source of spatial data termed as Volunteered Geographic Information (VGI) by Mike Goodchild. Although, VGI has produced previously unavailable data assets, and enriched existing ones. But its quality can be highly variable and challengeable. This presents several challenges to potential end users who are concerned about the validation and the quality assurance of the data which are collected. Almost, all the existing researches are based on how to find accurate VGI data from existing VGI data which consist of a) comparing the VGI data with the accurate official data, or b) in cases that there is no access to correct data; therefore, looking for an alternative way to determine the quality of VGI data is essential, and so forth. In this paper it has been attempt to develop a useful method to reach this goal. In this process, the positional accuracy of linear feature of Iran, Tehran OSM data have been analyzed.

Remote Sensing for Crop Water Management: From ET Modelling to Services for the End Users.

PubMed

Calera, Alfonso; Campos, Isidro; Osann, Anna; D'Urso, Guido; Menenti, Massimo

2017-05-11

The experiences gathered during the past 30 years support the operational use of irrigation scheduling based on frequent multi-spectral image data. Currently, the operational use of dense time series of multispectral imagery at high spatial resolution makes monitoring of crop biophysical parameters feasible, capturing crop water use across the growing season, with suitable temporal and spatial resolutions. These achievements, and the availability of accurate forecasting of meteorological data, allow for precise predictions of crop water requirements with unprecedented spatial resolution. This information is greatly appreciated by the end users, i.e., professional farmers or decision-makers, and can be provided in an easy-to-use manner and in near-real-time by using the improvements achieved in web-GIS methodologies (Geographic Information Systems based on web technologies). This paper reviews the most operational and explored methods based on optical remote sensing for the assessment of crop water requirements, identifying strengths and weaknesses and proposing alternatives to advance towards full operational application of this methodology. In addition, we provide a general overview of the tools, which facilitates co-creation and collaboration with stakeholders, paying special attention to these approaches based on web-GIS tools.

Design of an integrated aerial image sensor

NASA Astrophysics Data System (ADS)

Xue, Jing; Spanos, Costas J.

2005-05-01

The subject of this paper is a novel integrated aerial image sensor (IAIS) system suitable for integration within the surface of an autonomous test wafer. The IAIS could be used as a lithography processing monitor, affording a "wafer's eye view" of the process, and therefore facilitating advanced process control and diagnostics without integrating (and dedicating) the sensor to the processing equipment. The IAIS is composed of an aperture mask and an array of photo-detectors. In order to retrieve nanometer scale resolution of the aerial image with a practical photo-detector pixel size, we propose a design of an aperture mask involving a series of spatial phase "moving" aperture groups. We demonstrate a design example aimed at the 65nm technology node through TEMPEST simulation. The optimized, key design parameters include an aperture width in the range of 30nm, aperture thickness in the range of 70nm, and offer a spatial resolution of about 5nm, all with comfortable fabrication tolerances. Our preliminary simulation work indicates the possibility of the IAIS being applied to the immersion lithography. A bench-top far-field experiment verifies that our approach of the spatial frequency down-shift through forming large Moire patterns is feasible.

Application of Advanced Fracture Mechanics Technology to Ensure Structural Reliability in Critical Titanium Structures,

DTIC Science & Technology

1982-11-22

RD-Ri42 354 APPLICATION OF ADVANCED FRACTURE MECHANICS TECHNOLOGY i/i TT ENSURE STRUCTURA..(U) 1WESTINGHOUSE RESEARCH FND DEVELOPMENT CENTER...I Iml .4. 47 Igo 12. 4 %B 1. __ ~. ~% ski Z L __ 12 APPLICATION OF ADVANCED FRACTURE MECHANICS -p TECHNOLOGY TO ENSURE STRUCTURAL RELIABILITY IN...Road W Pilttsburgh. Pennsylvania 15235 84 06 18 207 APPLICATION OF ADVANCED FRACTURE MECHANICS TECHNOLOGY TO ENSURE STRUCTURAL RELIABILITY IN CRITICAL

Advanced Training Technologies and Learning Environments

NASA Technical Reports Server (NTRS)

Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

1999-01-01

This document contains the proceedings of the Workshop on Advanced Training Technologies and Learning Environments held at NASA Langley Research Center, Hampton, Virginia, March 9-10, 1999. The workshop was jointly sponsored by the University of Virginia's Center for Advanced Computational Technology and NASA. Workshop attendees were from NASA, other government agencies, industry, and universities. The objective of the workshop was to assess the status and effectiveness of different advanced training technologies and learning environments.

There and back again: An oceanographer's approach to delving into -and returning from- the unknown.

NASA Astrophysics Data System (ADS)

Girguis, P. R.; Hoer, D.; Michel, A.; Wankel, S. D.; Farr, N.; Pontbriand, C.; Raineault, N.

2017-12-01

Modern oceanographers explore the ocean through a combination of human-operated and autonomous instruments. Our understanding of the ocean and its denizens is advancing at a remarkable rate, and yet we still possess a rudimentary knowledge of the ocean. We largely view the ocean as the sum of its parts, and have a limited understanding of the relationships and synergies that exist within the ocean system. This tendency is, to a large extent, a result of how we conduct our science. Expedition-based science, in which scientists or autonomous vehicles set out on a mission for a prescribed period of time, tends to result in data with great spatial resolution (as samples are often taken while underway) but very limited temporal resolution (as ships cannot stay in one place for more than several weeks). The advent of seafloor and water-column "observatories" provided an unprecedented opportunity to conduct long-term studies with incredible temporal resolution, but limited spatial resolution. Therein lies the challenge of studying processes in the ocean, our world's most massive habitat. While we may never be able to "keep our thumb on the pulse" of every measurable factor in the ocean, we as a community are developing new technologies that permit us to better examine our oceans and to sustain a nearly continuous scientific presence in the deep sea. Here we present some of the latest developments -as well as the lessons- from exploring our own inner space. We will discuss technologies and methods that have helped us (and our community) bring autonomy to the exploration of our ocean. We will also present our data from recent efforts aimed at examining the relationships among abiotic and biological processes in our ocean. These technologies and methods can help us unlock the mysteries of the cosmos, in particular that enduring question of whether life exists on other celestial bodies. We posit that fostering a rich and extensive collaboration among ocean and space scientists is critical if we are to advance our understanding of other ocean worlds, such as Enceladus and Europa, beyond the scope of current missions and technologies. In essence, it may be our increasing ability to peer into the ocean depths that will allow us to better peer into the cosmos.

Impact of scientific and technological advances.

PubMed

Dragan, I F; Dalessandri, D; Johnson, L A; Tucker, A; Walmsley, A D

2018-03-01

Advancements in research and technology are transforming our world. The dental profession is changing too, in the light of scientific discoveries that are advancing biological technology-from new biomaterials to unravelling the genetic make-up of the human being. As health professionals, we embrace a model of continuous quality improvement and lifelong learning. Our pedagogical approach to incorporating the plethora of scientific-technological advancements calls for us to shift our paradigm from emphasis on skill acquisition to knowledge application. The 2017 ADEE/ADEA workshop provided a forum to explore and discuss strategies to ensure faculty, students and, ultimately, patients are best positioned to exploit the opportunities that arise from integrating new technological advances and research outcomes. Participants discussed methods of incorporating the impact of new technologies and research findings into the education of our dental students. This report serves as a signpost of the way forward and how to promote incorporation of research and technology advances and lifelong learning into the dental education curriculum. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Benefits of advanced technology in industrial cogeneration

NASA Technical Reports Server (NTRS)

Barna, G. J.; Burns, R. K.

1979-01-01

This broad study is aimed at identifying the most attractive advanced energy conversion systems for industrial cogeneration for the 1985 to 2000 time period and assessing the advantages of advanced technology systems compared to using today's commercially available technology. Energy conversion systems being studied include those using steam turbines, open cycle gas turbines, combined cycles, diesel engines, Stirling engines, closed cycle gas turbines, phosphoric acid and molten carbonate fuel cells and thermionics. Specific cases using today's commercially available technology are being included to serve as a baseline for assessing the advantages of advanced technology.

Advanced technology and the Space Shuttle /10th Von Karman Lecture/.

NASA Technical Reports Server (NTRS)

Love, E. S.

1973-01-01

Selected topics in technology advancement related to the space shuttle are examined. Contributions from long-range research prior to the advent of the 'shuttle-focused technology program' of the past 3 years are considered together with highlights from the latter. Attention is confined to three of the shuttle's seven principal technology areas: aerothermodynamics/configurations, dynamics/aeroelasticity, and structures/materials. Some observations are presented on the shuttle's origin, the need to sustain advanced research, and future systems that could emerge from a combination of shuttle and non-shuttle technology advancements.

Space station systems technology study (add-on task). Volume 2: Trade study and technology selection

NASA Technical Reports Server (NTRS)

1985-01-01

The current Space Station Systems Technology Study add on task was an outgrowth of the Advanced Platform Systems Technology Study (APSTS) that was completed in April 1983 and the subsequent Space Station System Technology Study completed in April 1984. The first APSTS proceeded from the identification of 106 technology topics to the selection of five for detailed trade studies. During the advanced platform study, the technical issues and options were evaluated through detailed trade processes, individual consideration was given to costs and benefits for the technologies identified for advancement, and advancement plans were developed. An approach similar to that was used in the subsequent study, with emphasis on system definition in four specific technology areas to facilitate a more in depth analysis of technology issues.

Spatially explicit modeling in ecology: A review

USGS Publications Warehouse

DeAngelis, Donald L.; Yurek, Simeon

2017-01-01

The use of spatially explicit models (SEMs) in ecology has grown enormously in the past two decades. One major advancement has been that fine-scale details of landscapes, and of spatially dependent biological processes, such as dispersal and invasion, can now be simulated with great precision, due to improvements in computer technology. Many areas of modeling have shifted toward a focus on capturing these fine-scale details, to improve mechanistic understanding of ecosystems. However, spatially implicit models (SIMs) have played a dominant role in ecology, and arguments have been made that SIMs, which account for the effects of space without specifying spatial positions, have an advantage of being simpler and more broadly applicable, perhaps contributing more to understanding. We address this debate by comparing SEMs and SIMs in examples from the past few decades of modeling research. We argue that, although SIMs have been the dominant approach in the incorporation of space in theoretical ecology, SEMs have unique advantages for addressing pragmatic questions concerning species populations or communities in specific places, because local conditions, such as spatial heterogeneities, organism behaviors, and other contingencies, produce dynamics and patterns that usually cannot be incorporated into simpler SIMs. SEMs are also able to describe mechanisms at the local scale that can create amplifying positive feedbacks at that scale, creating emergent patterns at larger scales, and therefore are important to basic ecological theory. We review the use of SEMs at the level of populations, interacting populations, food webs, and ecosystems and argue that SEMs are not only essential in pragmatic issues, but must play a role in the understanding of causal relationships on landscapes.

Development of a Geometric Spatial Visualization Tool

ERIC Educational Resources Information Center

Ganesh, Bibi; Wilhelm, Jennifer; Sherrod, Sonya

2009-01-01

This paper documents the development of the Geometric Spatial Assessment. We detail the development of this instrument which was designed to identify middle school students' strategies and advancement in understanding of four geometric concept domains (geometric spatial visualization, spatial projection, cardinal directions, and periodic patterns)…

National Coalition of Advanced Technology Centers Proposal to the Nation.

ERIC Educational Resources Information Center

National Coalition of Advanced Technology Centers, Waco, TX.

In 1988, nine institutions operating advanced technology centers (ATC's) to provide workers with up-to-date technical skills formed the National Coalition of Advanced Technology Centers (NCATC). The center was established to increase awareness of ATC's, serve as a forum for the discussion and demonstration of new and underused technologies,…

Space Technology Mission Directorate Game Changing Development Program FY2015 Annual Program Review: Advanced Manufacturing Technology

NASA Technical Reports Server (NTRS)

Vickers, John; Fikes, John

2015-01-01

The Advance Manufacturing Technology (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of the Initiative is the Advanced Manufacturing National Program Office (AMNPO), which includes participation from all federal agencies involved in U.S. manufacturing. In support of the AMNPO the AMT Project supports building and Growing the National Network for Manufacturing Innovation through a public-private partnership designed to help the industrial community accelerate manufacturing innovation. Integration with other projects/programs and partnerships: STMD (Space Technology Mission Directorate), HEOMD, other Centers; Industry, Academia; OGA's (e.g., DOD, DOE, DOC, USDA, NASA, NSF); Office of Science and Technology Policy, NIST Advanced Manufacturing Program Office; Generate insight within NASA and cross-agency for technology development priorities and investments. Technology Infusion Plan: PC; Potential customer infusion (TDM, HEOMD, SMD, OGA, Industry); Leverage; Collaborate with other Agencies, Industry and Academia; NASA roadmap. Initiatives include: Advanced Near Net Shape Technology Integrally Stiffened Cylinder Process Development (launch vehicles, sounding rockets); Materials Genome; Low Cost Upper Stage-Class Propulsion; Additive Construction with Mobile Emplacement (ACME); National Center for Advanced Manufacturing.

Advancing automation and robotics technology for the Space Station Freedom and for the US economy

NASA Technical Reports Server (NTRS)

1990-01-01

In April 1985, the NASA Advanced Technology Advisory Committee (ATAC) reported to Congress the results of its studies on advanced automation and robotics technology for use on Space Station Freedom. This material was documented in the initial report (NASA Technical Memorandum 87566). The progress made by Levels 1, 2, and 3 of the Office of Space Station in developing and applying advanced automation and robotics technology are described. Emphasis was placed upon the Space Station Freedom Program responses to specific recommendations made in ATAC Progress Report 9, the Flight Telerobotic Servicer, the Advanced Development Program, and the Data Management System. Assessments are presented for these and other areas as they apply to the advancement of automation and robotics technology for the Space Station Freedom.

Photovoltaic options for solar electric propulsion

NASA Technical Reports Server (NTRS)

Stella, Paul M.; Flood, Dennis J.

1990-01-01

During the past decade, a number of advances have occurred in solar cell and array technology. These advances have lead to performance improvement for both conventional space arrays and for advanced technology arrays. Performance enhancements have occurred in power density, specific power, and environmental capability. Both state-of-the-art and advanced development cells and array technology are discussed. Present technology will include rigid, rollout, and foldout flexible substrate designs, with silicon and GaAs solar cells. The use of concentrator array systems is also discussed based on both DOD and NASA efforts. The benefits of advanced lightweight array technology, for both near term and far term utilization, and of advanced high efficiency, thin, radiation resistant cells is examined. This includes gallium arsenide on germaniun substrates, indium phosphide, and thin film devices such as copper indium diselenide.

Development of a prototype spatial information processing system for hydrologic research

NASA Technical Reports Server (NTRS)

Sircar, Jayanta K.

1991-01-01

Significant advances have been made in the last decade in the areas of Geographic Information Systems (GIS) and spatial analysis technology, both in hardware and software. Science user requirements are so problem specific that currently no single system can satisfy all of the needs. The work presented here forms part of a conceptual framework for an all-encompassing science-user workstation system. While definition and development of the system as a whole will take several years, it is intended that small scale projects such as the current work will address some of the more short term needs. Such projects can provide a quick mechanism to integrate tools into the workstation environment forming a larger, more complete hydrologic analysis platform. Described here are two components that are very important to the practical use of remote sensing and digital map data in hydrology. Described here is a graph-theoretic technique to rasterize elevation contour maps. Also described is a system to manipulate synthetic aperture radar (SAR) data files and extract soil moisture data.

Example-Based Super-Resolution Fluorescence Microscopy.

PubMed

Jia, Shu; Han, Boran; Kutz, J Nathan

2018-04-23

Capturing biological dynamics with high spatiotemporal resolution demands the advancement in imaging technologies. Super-resolution fluorescence microscopy offers spatial resolution surpassing the diffraction limit to resolve near-molecular-level details. While various strategies have been reported to improve the temporal resolution of super-resolution imaging, all super-resolution techniques are still fundamentally limited by the trade-off associated with the longer image acquisition time that is needed to achieve higher spatial information. Here, we demonstrated an example-based, computational method that aims to obtain super-resolution images using conventional imaging without increasing the imaging time. With a low-resolution image input, the method provides an estimate of its super-resolution image based on an example database that contains super- and low-resolution image pairs of biological structures of interest. The computational imaging of cellular microtubules agrees approximately with the experimental super-resolution STORM results. This new approach may offer potential improvements in temporal resolution for experimental super-resolution fluorescence microscopy and provide a new path for large-data aided biomedical imaging.

Deterministic Creation of Macroscopic Cat States

PubMed Central

Lombardo, Daniel; Twamley, Jason

2015-01-01

Despite current technological advances, observing quantum mechanical effects outside of the nanoscopic realm is extremely challenging. For this reason, the observation of such effects on larger scale systems is currently one of the most attractive goals in quantum science. Many experimental protocols have been proposed for both the creation and observation of quantum states on macroscopic scales, in particular, in the field of optomechanics. The majority of these proposals, however, rely on performing measurements, making them probabilistic. In this work we develop a completely deterministic method of macroscopic quantum state creation. We study the prototypical optomechanical Membrane In The Middle model and show that by controlling the membrane’s opacity, and through careful choice of the optical cavity initial state, we can deterministically create and grow the spatial extent of the membrane’s position into a large cat state. It is found that by using a Bose-Einstein condensate as a membrane high fidelity cat states with spatial separations of up to ∼300 nm can be achieved. PMID:26345157

Investigating Bacterial-Animal Symbioses with Light Sheet Microscopy

PubMed Central

Taormina, Michael J.; Jemielita, Matthew; Stephens, W. Zac; Burns, Adam R.; Troll, Joshua V.; Parthasarathy, Raghuveer; Guillemin, Karen

2014-01-01

SUMMARY Microbial colonization of the digestive tract is a crucial event in vertebrate development, required for maturation of host immunity and establishment of normal digestive physiology. Advances in genomic, proteomic, and metabolomic technologies are providing a more detailed picture of the constituents of the intestinal habitat, but these approaches lack the spatial and temporal resolution needed to characterize the assembly and dynamics of microbial communities in this complex environment. We report the use of light sheet microscopy to provide high resolution imaging of bacterial colonization of the zebrafish intestine. The methodology allows us to characterize bacterial population dynamics across the entire organ and the behaviors of individual bacterial and host cells throughout the colonization process. The large four-dimensional datasets generated by these imaging approaches require new strategies for image analysis. When integrated with other “omics” datasets, information about the spatial and temporal dynamics of microbial cells within the vertebrate intestine will provide new mechanistic insights into how microbial communities assemble and function within hosts. PMID:22983029

Navy Applications Experience with Small Wind Power Systems

DTIC Science & Technology

1985-05-01

present state-of-the-art in small WECS technology, including environmental concerns, is reviewed. Also presented is how the technology is advancing to...environmental concerns, is reviewed. Also presented is how the technology is advancing to improve reliability and avail- ability for effectively using...VAWT technology is still in its early stages of development. The horizontal-axis wind turbine (HAWT) technology has advanced to third and fourth

D Object Classification Based on Thermal and Visible Imagery in Urban Area

NASA Astrophysics Data System (ADS)

Hasani, H.; Samadzadegan, F.

2015-12-01

The spatial distribution of land cover in the urban area especially 3D objects (buildings and trees) is a fundamental dataset for urban planning, ecological research, disaster management, etc. According to recent advances in sensor technologies, several types of remotely sensed data are available from the same area. Data fusion has been widely investigated for integrating different source of data in classification of urban area. Thermal infrared imagery (TIR) contains information on emitted radiation and has unique radiometric properties. However, due to coarse spatial resolution of thermal data, its application has been restricted in urban areas. On the other hand, visible image (VIS) has high spatial resolution and information in visible spectrum. Consequently, there is a complementary relation between thermal and visible imagery in classification of urban area. This paper evaluates the potential of aerial thermal hyperspectral and visible imagery fusion in classification of urban area. In the pre-processing step, thermal imagery is resampled to the spatial resolution of visible image. Then feature level fusion is applied to construct hybrid feature space include visible bands, thermal hyperspectral bands, spatial and texture features and moreover Principle Component Analysis (PCA) transformation is applied to extract PCs. Due to high dimensionality of feature space, dimension reduction method is performed. Finally, Support Vector Machines (SVMs) classify the reduced hybrid feature space. The obtained results show using thermal imagery along with visible imagery, improved the classification accuracy up to 8% respect to visible image classification.

Paramagnetic and fluorescent liposomes for target-specific imaging and therapy of tumor angiogenesis

PubMed Central

Kluza, Ewelina; Van Tilborg, Geralda A. F.; van der Schaft, Daisy W. J.; Griffioen, Arjan W.; Mulder, Willem J. M.; Nicolay, Klaas

2010-01-01

Angiogenesis is essential for tumor growth and metastatic potential and for that reason considered an important target for tumor treatment. Noninvasive imaging technologies, capable of visualizing tumor angiogenesis and evaluating the efficacy of angiostatic therapies, are therefore becoming increasingly important. Among the various imaging modalities, magnetic resonance imaging (MRI) is characterized by a superb spatial resolution and anatomical soft-tissue contrast. Revolutionary advances in contrast agent chemistry have delivered versatile angiogenesis-specific molecular MRI contrast agents. In this paper, we review recent advances in the preclinical application of paramagnetic and fluorescent liposomes for noninvasive visualization of the molecular processes involved in tumor angiogenesis. This liposomal contrast agent platform can be prepared with a high payload of contrast generating material, thereby facilitating its detection, and is equipped with one or more types of targeting ligands for binding to specific molecules expressed at the angiogenic site. Multimodal liposomes endowed with contrast material for complementary imaging technologies, e.g., MRI and optical, can be exploited to gain important preclinical insights into the mechanisms of binding and accumulation at angiogenic vascular endothelium and to corroborate the in vivo findings. Interestingly, liposomes can be designed to contain angiostatic therapeutics, allowing for image-supervised drug delivery and subsequent monitoring of therapeutic efficacy. PMID:20390447

Archaeal Diversity in Biofilm Technologies Applied to Treat Urban and Industrial Wastewater: Recent Advances and Future Prospects

PubMed Central

Calderón, Kadiya; González-Martínez, Alejandro; Gómez-Silván, Cinta; Osorio, Francisco; Rodelas, Belén; González-López, Jesús

2013-01-01

Biological wastewater treatment (WWT) frequently relies on biofilms for the removal of anthropogenic contaminants. The use of inert carrier materials to support biofilm development is often required, although under certain operating conditions microorganisms yield structures called granules, dense aggregates of self-immobilized cells with the characteristics of biofilms maintained in suspension. Molecular techniques have been successfully applied in recent years to identify the prokaryotic communities inhabiting biofilms in WWT plants. Although methanogenic Archaea are widely acknowledged as key players for the degradation of organic matter in anaerobic bioreactors, other biotechnological functions fulfilled by Archaea are less explored, and research on their significance and potential for WWT is largely needed. In addition, the occurrence of biofilms in WWT plants can sometimes be a source of operational problems. This is the case for membrane bioreactors (MBR), an advanced technology that combines conventional biological treatment with membrane filtration, which is strongly limited by biofouling, defined as the undesirable accumulation of microbial biofilms and other materials on membrane surfaces. The prevalence and spatial distribution of archaeal communities in biofilm-based WWT as well as their role in biofouling are reviewed here, in order to illustrate the significance of this prokaryotic cellular lineage in engineered environments devoted to WWT. PMID:24022691

An Integrated Quantum Dot Barcode Smartphone Optical Device for Wireless Multiplexed Diagnosis of Infected Patients

NASA Astrophysics Data System (ADS)

Ming, Kevin

Integrating mobile-cellular devices with multiplex molecular diagnostics can potentially provide the most powerful platform for tracking, managing and preventing the transmission of infectious diseases. With over 6.9 billion subscriptions globally, handheld mobile-cellular devices can be programmed to spatially map, temporally track, and transmit information on infections over wide geographical space and boundaries. Current cell phone diagnostic technologies have poor limit of detection, dynamic range, and cannot detect multiple pathogen targets simultaneously, limiting their utility to single infections with high load. Here we combined recent advances in quantum dot barcode technology for molecular detection with smartphones to engineer a simple and low-cost chip-based wireless multiplex diagnostic device. We validated our device using a variety of synthetic genomic targets for the respiratory virus and blood-borne pathogens, and demonstrated that it could detect clinical samples after simple amplification. More importantly, we confirmed that the device is capable of detecting patients infected with a single or multiple infectious pathogens (e.g., HIV and hepatitis B) in a single test. This device advances the capacity for global surveillance of infectious diseases and has the potential to accelerate knowledge exchange-transfer of emerging or exigent disease threats with healthcare and military organizations in real-time.

Free-standing carbon nanotube composite sensing skin for distributed strain sensing in structures

NASA Astrophysics Data System (ADS)

Burton, Andrew R.; Minegishi, Kaede; Kurata, Masahiro; Lynch, Jerome P.

2014-04-01

The technical challenges of managing the health of critical infrastructure systems necessitate greater structural sensing capabilities. Among these needs is the ability for quantitative, spatial damage detection on critical structural components. Advances in material science have now opened the door for novel and cost-effective spatial sensing solutions specially tailored for damage detection in structures. However, challenges remain before spatial damage detection can be realized. Some of the technical challenges include sensor installations and extensive signal processing requirements. This work addresses these challenges by developing a patterned carbon nanotube composite thin film sensor whose pattern has been optimized for measuring the spatial distribution of strain. The carbon nanotube-polymer nanocomposite sensing material is fabricated on a flexible polyimide substrate using a layer-by-layer deposition process. The thin film sensors are then patterned into sensing elements using optical lithography processes common to microelectromechanical systems (MEMS) technologies. The sensor array is designed as a series of sensing elements with varying width to provide insight on the limitations of such patterning and implications of pattern geometry on sensing signals. Once fabrication is complete, the substrate and attached sensor are epoxy bonded to a poly vinyl composite (PVC) bar that is then tested with a uniaxial, cyclic load pattern and mechanical response is characterized. The fabrication processes are then utilized on a larger-scale to develop and instrument a component-specific sensing skin in order to observe the strain distribution on the web of a steel beam. The instrumented beam is part of a larger steel beam-column connection with a concrete slab in composite action. The beam-column subassembly is laterally loaded and strain trends in the web are observed using the carbon nanotube composite sensing skin. The results are discussed in the context of understanding the properties of the thin film sensor and how it may be advanced toward structural sensing applications.

Combining multiple approaches and optimized data resolution for an improved understanding of stream temperature dynamics of a forested headwater basin in the Southern Appalachians

NASA Astrophysics Data System (ADS)

Belica, L.; Mitasova, H.; Caldwell, P.; McCarter, J. B.; Nelson, S. A. C.

2017-12-01

Thermal regimes of forested headwater streams continue to be an area of active research as climatic, hydrologic, and land cover changes can influence water temperature, a key aspect of aquatic ecosystems. Widespread monitoring of stream temperatures have provided an important data source, yielding insights on the temporal and spatial patterns and the underlying processes that influence stream temperature. However, small forested streams remain challenging to model due to the high spatial and temporal variability of stream temperatures and the climatic and hydrologic conditions that drive them. Technological advances and increased computational power continue to provide new tools and measurement methods and have allowed spatially explicit analyses of dynamic natural systems at greater temporal resolutions than previously possible. With the goal of understanding how current stream temperature patterns and processes may respond to changing landcover and hydroclimatoligical conditions, we combined high-resolution, spatially explicit geospatial modeling with deterministic heat flux modeling approaches using data sources that ranged from traditional hydrological and climatological measurements to emerging remote sensing techniques. Initial analyses of stream temperature monitoring data revealed that high temporal resolution (5 minutes) and measurement resolutions (<0.1°C) were needed to adequately describe diel stream temperature patterns and capture the differences between paired 1st order and 4th order forest streams draining north and south facing slopes. This finding along with geospatial models of subcanopy solar radiation and channel morphology were used to develop hypotheses and guide field data collection for further heat flux modeling. By integrating multiple approaches and optimizing data resolution for the processes being investigated, small, but ecologically significant differences in stream thermal regimes were revealed. In this case, multi-approach research contributed to the identification of the dominant mechanisms driving stream temperature in the study area and advanced our understanding of the current thermal fluxes and how they may change as environmental conditions change in the future.

Fidelity by design: Yoctoreactor and binder trap enrichment for small-molecule DNA-encoded libraries and drug discovery.

PubMed

Blakskjaer, Peter; Heitner, Tara; Hansen, Nils Jakob Vest

2015-06-01

DNA-encoded small-molecule library (DEL) technology allows vast drug-like small molecule libraries to be efficiently synthesized in a combinatorial fashion and screened in a single tube method for binding, with an assay readout empowered by advances in next generation sequencing technology. This approach has increasingly been applied as a viable technology for the identification of small-molecule modulators to protein targets and as precursors to drugs in the past decade. Several strategies for producing and for screening DELs have been devised by both academic and industrial institutions. This review highlights some of the most significant and recent strategies along with important results. A special focus on the production of high fidelity DEL technologies with the ability to eliminate screening noise and false positives is included: using a DNA junction called the Yoctoreactor, building blocks (BBs) are spatially confined at the center of the junction facilitating both the chemical reaction between BBs and encoding of the synthetic route. A screening method, known as binder trap enrichment, permits DELs to be screened robustly in a homogeneous manner delivering clean data sets and potent hits for even the most challenging targets. Copyright © 2015 Elsevier Ltd. All rights reserved.

Light-field and holographic three-dimensional displays [Invited].

PubMed

Yamaguchi, Masahiro

2016-12-01

A perfect three-dimensional (3D) display that satisfies all depth cues in human vision is possible if a light field can be reproduced exactly as it appeared when it emerged from a real object. The light field can be generated based on either light ray or wavefront reconstruction, with the latter known as holography. This paper first provides an overview of the advances of ray-based and wavefront-based 3D display technologies, including integral photography and holography, and the integration of those technologies with digital information systems. Hardcopy displays have already been used in some applications, whereas the electronic display of a light field is under active investigation. Next, a fundamental question in this technology field is addressed: what is the difference between ray-based and wavefront-based methods for light-field 3D displays? In considering this question, it is of particular interest to look at the technology of holographic stereograms. The phase information in holography contributes to the resolution of a reconstructed image, especially for deep 3D images. Moreover, issues facing the electronic display system of light fields are discussed, including the resolution of the spatial light modulator, the computational techniques of holography, and the speckle in holographic images.

Infrared small target tracking based on SOPC

NASA Astrophysics Data System (ADS)

Hu, Taotao; Fan, Xiang; Zhang, Yu-Jin; Cheng, Zheng-dong; Zhu, Bin

2011-01-01

The paper presents a low cost FPGA based solution for a real-time infrared small target tracking system. A specialized architecture is presented based on a soft RISC processor capable of running kernel based mean shift tracking algorithm. Mean shift tracking algorithm is realized in NIOS II soft-core with SOPC (System on a Programmable Chip) technology. Though mean shift algorithm is widely used for target tracking, the original mean shift algorithm can not be directly used for infrared small target tracking. As infrared small target only has intensity information, so an improved mean shift algorithm is presented in this paper. How to describe target will determine whether target can be tracked by mean shift algorithm. Because color target can be tracked well by mean shift algorithm, imitating color image expression, spatial component and temporal component are advanced to describe target, which forms pseudo-color image. In order to improve the processing speed parallel technology and pipeline technology are taken. Two RAM are taken to stored images separately by ping-pong technology. A FLASH is used to store mass temp data. The experimental results show that infrared small target is tracked stably in complicated background.

Flight Test Results of the Earth Observing-1 Advanced Land Imager Advanced Land Imager

NASA Astrophysics Data System (ADS)

Mendenhall, Jeffrey A.; Lencioni, Donald E.; Hearn, David R.; Digenis, Constantine J.

2002-09-01

The Advanced Land Imager (ALI) is the primary instrument on the Earth Observing-1 spacecraft (EO-1) and was developed under NASA's New Millennium Program (NMP). The NMP mission objective is to flight-validate advanced technologies that will enable dramatic improvements in performance, cost, mass, and schedule for future, Landsat-like, Earth Science Enterprise instruments. ALI contains a number of innovative features designed to achieve this objective. These include the basic instrument architecture, which employs a push-broom data collection mode, a wide field-of-view optical design, compact multi-spectral detector arrays, non-cryogenic HgCdTe for the short wave infrared bands, silicon carbide optics, and a multi-level solar calibration technique. The sensor includes detector arrays that operate in ten bands, one panchromatic, six VNIR and three SWIR, spanning the range from 0.433 to 2.35 μm. Launched on November 21, 2000, ALI instrument performance was monitored during its first year on orbit using data collected during solar, lunar, stellar, and earth observations. This paper will provide an overview of EO-1 mission activities during this period. Additionally, the on-orbit spatial and radiometric performance of the instrument will be compared to pre-flight measurements and the temporal stability of ALI will be presented.

Advanced information processing system for advanced launch system: Hardware technology survey and projections

NASA Technical Reports Server (NTRS)

Cole, Richard

1991-01-01

The major goals of this effort are as follows: (1) to examine technology insertion options to optimize Advanced Information Processing System (AIPS) performance in the Advanced Launch System (ALS) environment; (2) to examine the AIPS concepts to ensure that valuable new technologies are not excluded from the AIPS/ALS implementations; (3) to examine advanced microprocessors applicable to AIPS/ALS, (4) to examine radiation hardening technologies applicable to AIPS/ALS; (5) to reach conclusions on AIPS hardware building blocks implementation technologies; and (6) reach conclusions on appropriate architectural improvements. The hardware building blocks are the Fault-Tolerant Processor, the Input/Output Sequencers (IOS), and the Intercomputer Interface Sequencers (ICIS).

Managing the Perception of Advanced Technology Risks in Mission Proposals

NASA Technical Reports Server (NTRS)

Bellisario, Sebastian Nickolai

2012-01-01

Through my work in the project proposal office I became interested in how technology advancement efforts affect competitive mission proposals. Technology development allows for new instruments and functionality. However, including technology advancement in a mission proposal often increases perceived risk. Risk mitigation has a major impact on the overall evaluation of the proposal and whether the mission is selected. In order to evaluate the different approaches proposals took I compared the proposals claims of heritage and technology advancement to the sponsor feedback provided in the NASA debriefs. I examined a set of Discovery 2010 Mission proposals to draw patterns in how they were evaluated and come up with a set of recommendations for future mission proposals in how they should approach technology advancement to reduce the perceived risk.

78 FR 15114 - Group Lotus plc; Grant of Petition for a Temporary Exemption From an Advanced Air Bag Requirement...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... went into effect, low volume manufacturers now have access to advanced air bag technology. Accordingly, NHTSA has concluded that the expense of advanced air bag technology is not now sufficient, in and of... into effect, low volume manufacturers now have access to advanced air bag technology.\\14\\ Accordingly...

Review Article—Dielectrophoresis: Status of the theory, technology, and applications

PubMed Central

Pethig, Ronald

2010-01-01

A review is presented of the present status of the theory, the developed technology and the current applications of dielectrophoresis (DEP). Over the past 10 years around 2000 publications have addressed these three aspects, and current trends suggest that the theory and technology have matured sufficiently for most effort to now be directed towards applying DEP to unmet needs in such areas as biosensors, cell therapeutics, drug discovery, medical diagnostics, microfluidics, nanoassembly, and particle filtration. The dipole approximation to describe the DEP force acting on a particle subjected to a nonuniform electric field has evolved to include multipole contributions, the perturbing effects arising from interactions with other cells and boundary surfaces, and the influence of electrical double-layer polarizations that must be considered for nanoparticles. Theoretical modelling of the electric field gradients generated by different electrode designs has also reached an advanced state. Advances in the technology include the development of sophisticated electrode designs, along with the introduction of new materials (e.g., silicone polymers, dry film resist) and methods for fabricating the electrodes and microfluidics of DEP devices (photo and electron beam lithography, laser ablation, thin film techniques, CMOS technology). Around three-quarters of the 300 or so scientific publications now being published each year on DEP are directed towards practical applications, and this is matched with an increasing number of patent applications. A summary of the US patents granted since January 2005 is given, along with an outline of the small number of perceived industrial applications (e.g., mineral separation, micropolishing, manipulation and dispensing of fluid droplets, manipulation and assembly of micro components). The technology has also advanced sufficiently for DEP to be used as a tool to manipulate nanoparticles (e.g., carbon nanotubes, nano wires, gold and metal oxide nanoparticles) for the fabrication of devices and sensors. Most efforts are now being directed towards biomedical applications, such as the spatial manipulation and selective separation∕enrichment of target cells or bacteria, high-throughput molecular screening, biosensors, immunoassays, and the artificial engineering of three-dimensional cell constructs. DEP is able to manipulate and sort cells without the need for biochemical labels or other bioengineered tags, and without contact to any surfaces. This opens up potentially important applications of DEP as a tool to address an unmet need in stem cell research and therapy. PMID:20697589

The impact of advanced technology on critical care. Dilemmas in the making.

PubMed

Aarons, D E

1998-12-01

Advanced technology has enhanced our ability to diagnose and treat critically ill patients, thereby assisting in prolonging life for many. However, its high cost has been prohibitive, and it may impose more burdens than benefits on some patients. Although technological advances have accelerated social change, many have also fuelled legal and ethical concerns. Consequently, the rationale for the use of advanced technology in the care of critically ill patients should be clear and ethically justified.

Community and Institutional Adaptation to Riverbank Erosion along the Jamuna River, Bangladesh

NASA Astrophysics Data System (ADS)

Ali, F. M. M.

2009-04-01

The paper examines adaptation to the river erosion hazard in Bangladesh through its most exacting river, the braided Jamuna. The Jamuna River has destroyed and continues to threaten significant areas of settlements, farmed land and infrastructure. Local communities experience a social disintegration and pauperisation which lasts for generations. Although advanced for several decades, the public engineering effort to mitigate the erosion is piecemeal and has had limited success to date. The research takes an interdisciplinary approach to the hazard, in both content and method. Using Remote Sensing data to distinguish regions of dormant, explosive, minimal and constant erosion, the physical morphology of the river is linked to the community adaptation through the creation of PPGIS mapping depicting historical institutional displacement. This spatial information is linked to the qualitative investigation focusing on the expression of values in adaptation by examining social structures and investigating technological development. Drawing on Bourdieu's ideas of fields, capital and habitus, interview data is gathered from: displacees; local elites; the engineering-science community; and the political-administrative structure. The analysis is conducted along four themes; the spatial history of community displacement; social values; institutional operation; and learning in practice. Findings show the marked persistence of displaced local institutions. Dormant erosion zones host the most displaced institutions, acting as refuges once the risk is lowered through engineering or serendipity. The non-material values deeply impacted by the hazard underpin the strong local aspiration for engineering intervention. However, political discontinuity, associated institutional instability and spatial biasing of construction hinders the success of erosion mitigation and the development of appropriate national technological expertise. The small national economic resource base, shortsighted negotiations with international lenders and reduced public confidence in water sector engineering are also confounding factors. Evidence suggests that social and technological progress occurs when values, institutional results and political commitment align.

Sound localization with communications headsets: comparison of passive and active systems.

PubMed

Abel, Sharon M; Tsang, Suzanne; Boyne, Stephen

2007-01-01

Studies have demonstrated that conventional hearing protectors interfere with sound localization. This research examines possible benefits from advanced communications devices. Horizontal plane sound localization was compared in normal-hearing males with the ears unoccluded and fitted with Peltor H10A passive attenuation earmuffs, Racal Slimgard II communications muffs in active noise reduction (ANR) and talk-through-circuitry (TTC) modes and Nacre QUIETPRO TM communications earplugs in off (passive attenuation) and push-to-talk (PTT) modes. Localization was assessed using an array of eight loudspeakers, two in each spatial quadrant. The stimulus was 75 dB SPL, 300-ms broadband noise. One block of 120 forced-choice loudspeaker identification trials was presented in each condition. Subjects responded using a laptop response box with a set of eight microswitches in the same configuration as the speaker array. A repeated measures ANOVA was applied to the dataset. The results reveal that the overall percent correct response was highest in the unoccluded condition (94%). A significant reduction of 24% was observed for the communications devices in TTC and PTT modes and a reduction of 49% for the passive muff and plug and muff with ANR. Disruption in performance was due to an increase in front-back reversal errors for mirror image spatial positions. The results support the conclusion that communications devices with advanced technologies are less detrimental to directional hearing than conventional, passive, limited amplification and ANR devices.

SYMPOSIUM ON MULTIMODALITY CARDIOVASCULAR MOLECULAR IMAGING IMAGING TECHNOLOGY - PART 2

PubMed Central

de Kemp, Robert A.; Epstein, Frederick H.; Catana, Ciprian; Tsui, Benjamin M.W.; Ritman, Erik L.

2013-01-01

Rationale The ability to trace or identify specific molecules within a specific anatomic location provides insight into metabolic pathways, tissue components and tracing of solute transport mechanisms. With the increasing use of small animals for research such imaging must have sufficiently high spatial resolution to allow anatomic localization as well as sufficient specificity and sensitivity to provide an accurate description of the molecular distribution and concentration. Methods Imaging methods based on electromagnetic radiation, such as PET, SPECT, MRI and CT, are increasingly applicable due to recent advances in novel scanner hardware, image reconstruction software and availability of novel molecules which have enhanced sensitivity in these methodologies. Results Micro-PET has been advanced by development of detector arrays that provide higher resolution and positron emitting elements that allow new molecular tracers to be labeled. Micro-MRI has been improved in terms of spatial resolution and sensitivity by increased magnet field strength and development of special purpose coils and associated scan protocols. Of particular interest is the associated ability to image local mechanical function and solute transport processes which can be directly related to the molecular information. This is further strengthened by the synergistic integration of the PET with MRI. Micro-SPECT has been improved by use of coded aperture imaging approaches as well as image reconstruction algorithms which can better deal with the photon limited scan data. The limited spatial resolution can be partially overcome by integrating the SPECT with CT. Micro-CT by itself provides exquisite spatial resolution of anatomy, but recent developments of high spatial resolution photon counting and spectrally-sensitive imaging arrays, combined with x-ray optical devices, have promise for actual molecular identification by virtue of the chemical bond lengths of molecules, especially of bio-polymers. Conclusion With the increasing use of small animals for evaluating new clinical imaging techniques as well as providing increased insights into patho-physiological phenomena, the availability of improved detection systems, scanning protocols and associated software, the repertoire of molecular imaging is greatly increased in sensitivity and specificity. PMID:20457793

Computer Technology-Integrated Projects Should not Supplant Craft Projects in Science Education

NASA Astrophysics Data System (ADS)

Klopp, Tabatha J.; Rule, Audrey C.; Suchsland Schneider, Jean; Boody, Robert M.

2014-03-01

The current emphasis on computer technology integration and narrowing of the curriculum has displaced arts and crafts. However, the hands-on, concrete nature of craft work in science modeling enables students to understand difficult concepts and to be engaged and motivated while learning spatial, logical, and sequential thinking skills. Analogy use is also helpful in understanding unfamiliar, complex science concepts. This study of 28 academically advanced elementary to middle-school students examined student work and perceptions during a science unit focused on four fossil organisms: crinoid, brachiopod, horn coral and trilobite. The study compared: (1) analogy-focused instruction to independent Internet research and (2) computer technology-rich products to crafts-based products. Findings indicate student products were more creative after analogy-based instruction and when made using technology. However, students expressed a strong desire to engage in additional craft work after making craft products and enjoyed making crafts more after analogy-focused instruction. Additionally, more science content was found in the craft products than the technology-rich products. Students expressed a particular liking for two of the fossil organisms because they had been modeled with crafts. The authors recommend that room should be retained for crafts in the science curriculum to model science concepts.

Advanced Manufacturing Technologies

NASA Technical Reports Server (NTRS)

Fikes, John

2016-01-01

Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

NOAA Office of Exploration and Research > Education > Overview

Science.gov Websites

Exploration Marine Archaeology Ocean and Coastal Mapping Advancing Technology Overview Technology Initiatives Coastal Mapping Advancing Technology Overview Technology Initiatives Science Overview Data Access Overview

Evaluation of micro-GPS receivers for tracking small-bodied mammals

PubMed Central

Shipley, Lisa A.; Forbey, Jennifer S.; Olsoy, Peter J.

2017-01-01

GPS telemetry markedly enhances the temporal and spatial resolution of animal location data, and recent advances in micro-GPS receivers permit their deployment on small mammals. One such technological advance, snapshot technology, allows for improved battery life by reducing the time to first fix via postponing recovery of satellite ephemeris (satellite location) data and processing of locations. However, no previous work has employed snapshot technology for small, terrestrial mammals. We evaluated performance of two types of micro-GPS (< 20 g) receivers (traditional and snapshot) on a small, semi-fossorial lagomorph, the pygmy rabbit (Brachylagus idahoensis), to understand how GPS errors might influence fine-scale assessments of space use and habitat selection. During stationary tests, microtopography (i.e., burrows) and satellite geometry had the largest influence on GPS fix success rate (FSR) and location error (LE). There was no difference between FSR while animals wore the GPS collars above ground (determined via light sensors) and FSR generated during stationary, above-ground trials, suggesting that animal behavior other than burrowing did not markedly influence micro-GPS errors. In our study, traditional micro-GPS receivers demonstrated similar FSR and LE to snapshot receivers, however, snapshot receivers operated inconsistently due to battery and software failures. In contrast, the initial traditional receivers deployed on animals experienced some breakages, but a modified collar design consistently functioned as expected. If such problems were resolved, snapshot technology could reduce the tradeoff between fix interval and battery life that occurs with traditional micro-GPS receivers. Our results suggest that micro-GPS receivers are capable of addressing questions about space use and resource selection by small mammals, but that additional techniques might be needed to identify use of habitat structures (e.g., burrows, tree cavities, rock crevices) that could affect micro-GPS performance and bias study results. PMID:28301495

CBEO:N, Chesapeake Bay Environmental Observatory as a Cyberinfrastructure Node

NASA Astrophysics Data System (ADS)

Zaslavsky, I.; Piasecki, M.; Whitenack, T.; Ball, W. P.; Murphy, R.

2008-12-01

Chesapeake Bay Environmental Observatory (CBEO) is an NSF-supported project focused on studying hypoxia in Chesapeake Bay using advanced cyberinfrastructure (CI) technologies. The project is organized around four concurrent and interacting activities: 1) CBEO:S provides science and management context for the use of CI technologies, focusing on hypoxia and its non-linear dynamics as affected by management and climate; 2) CBEO:T constructs a locally-accessible CBEO test bed prototype centered on spatio-temporal interpolation and advanced querying of model runs; 3) CBEO:N incorporates the test bed CI into national environmental observation networks, and 4) CBEO:E develops education and outreach components of the project that translate observational science for public consumption. CBEO:N activities, which are the focus of this paper, are four-fold: - constructing an online project portal to enable researchers to publish, discover, query, visualize and integrate project-related datasets of different types. The portal is based on the technologies developed within the GEON (the Geosciences Network) project, and has established the CBEO project data server as part of the GEON network of servers; * developing a CBEO node within the WATERS network, taking advantage of the CUAHSI Hydrologic Information System (HIS) Server technology that supports online publication of observation data as web services, and ontology-assisted data discovery; *developing new data structures and metadata in order to describe water quality observational data, and model run output, obtained for the Chesapeake Bay area, using data structures adopted and modified from the Observations Data Model of CUAHSI HIS; * prototyping CBEO tools that can be re-used through the portal, in particular implementing a portal version of R-based spatial interpolation tools. The paper describes recent accomplishments in these four development areas, and demonstrates how CI approaches transform research and data sharing in environmental observing systems.

Modern and prospective technologies for weather modification activities: A look at integrating unmanned aircraft systems

NASA Astrophysics Data System (ADS)

Axisa, Duncan; DeFelice, Tom P.

2016-09-01

Present-day weather modification technologies are scientifically based and have made controlled technological advances since the late 1990s, early 2000s. The technological advances directly related to weather modification have primarily been in the decision support and evaluation based software and modeling areas. However, there have been some technological advances in other fields that might now be advanced enough to start considering their usefulness for improving weather modification operational efficiency and evaluation accuracy. We consider the programmatic aspects underlying the development of new technologies for use in weather modification activities, identifying their potential benefits and limitations. We provide context and initial guidance for operators that might integrate unmanned aircraft systems technology in future weather modification operations.

Advanced-technology space station study: Summary of systems and pacing technologies

NASA Technical Reports Server (NTRS)

Butterfield, A. J.; Garn, P. A.; King, C. B.; Queijo, M. J.

1990-01-01

The principal system features defined for the Advanced Technology Space Station are summarized and the 21 pacing technologies identified during the course of the study are described. The descriptions of system configurations were extracted from four previous study reports. The technological areas focus on those systems particular to all large spacecraft which generate artificial gravity by rotation. The summary includes a listing of the functions, crew requirements and electrical power demand that led to the studied configuration. The pacing technologies include the benefits of advanced materials, in-orbit assembly requirements, stationkeeping, evaluations of electrical power generation alternates, and life support systems. The descriptions of systems show the potential for synergies and identifies the beneficial interactions that can result from technological advances.

Engine Seal Technology Requirements to Meet NASA's Advanced Subsonic Technology Program Goals

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M.; Hendricks, Robert C.

1994-01-01

Cycle studies have shown the benefits of increasing engine pressure ratios and cycle temperatures to decrease engine weight and improve performance of commercial turbine engines. NASA is working with industry to define technology requirements of advanced engines and engine technology to meet the goals of NASA's Advanced Subsonic Technology Initiative. As engine operating conditions become more severe and customers demand lower operating costs, NASA and engine manufacturers are investigating methods of improving engine efficiency and reducing operating costs. A number of new technologies are being examined that will allow next generation engines to operate at higher pressures and temperatures. Improving seal performance - reducing leakage and increasing service life while operating under more demanding conditions - will play an important role in meeting overall program goals of reducing specific fuel consumption and ultimately reducing direct operating costs. This paper provides an overview of the Advanced Subsonic Technology program goals, discusses the motivation for advanced seal development, and highlights seal technology requirements to meet future engine performance goals.

Assessment of advanced technologies for transit and rideshare applications : final report

DOT National Transportation Integrated Search

This report presents the results of a study to examine advanced technologies and systems that can be applied to high occupancy vehicles, ridesharing and transit needs. Advanced technologies can be used to encourage the use of transit and rideshare fa...

Vehicle safety : technologies, challenges, and research development expenditures for advanced air bags

DOT National Transportation Integrated Search

2001-06-01

Some advanced air bag technologies are currently being installed in vehicles and others are still being developed. The principal advanced technology that is currently being installed in some vehicles is air bags that can inflate with lower or higher ...

Application of advanced technologies to derivatives of current small transport aircraft

NASA Technical Reports Server (NTRS)

Renze, P. P.; Terry, J. E.

1981-01-01

Mission requirements of the derivative design were the same as the baseline to readily identify the advanced technology benefits achieved. Advanced technologies investigated were in the areas of propulsion, structures and aerodynamics and a direct operating cost benefit analysis conducted to identify the most promising. Engine improvements appear most promising and combined with propeller, airfoil, surface coating and composite advanced technologies give a 21-25 percent DOC savings. A 17 percent higher acquisition cost is offset by a 34 percent savings in fuel used.

An overview of DARPA's advanced space technology program

NASA Astrophysics Data System (ADS)

Nicastri, E.; Dodd, J.

1993-02-01

The Defense Advanced Research Projects Agency (DARPA) is the central research and development organization of the DoD and, as such, has the primary responsibility for the maintenance of U.S. technological superiority over potential adversaries. DARPA's programs focus on technology development and proof-of-concept demonstrations of both evolutionary and revolutionary approaches for improved strategic, conventional, rapid deployment and sea power forces, and on the scientific investigation into advanced basic technologies of the future. DARPA can move quickly to exploit new ideas and concepts by working directly with industry and universities. For four years, DARPA's Advanced Space Technology Program (ASTP) has addressed various ways to improve the performance of small satellites and launch vehicles. The advanced technologies that are being and will be developed by DARPA for small satellites can be used just as easily on large satellites. The primary objective of the ASTP is to enhance support to operational commanders by developing and applying advanced technologies that will provide cost-effective, timely, flexible, and responsive space systems. Fundamental to the ASTP effort is finding new ways to do business with the goal of quickly inserting new technologies into DoD space systems while reducing cost. In our view, these methods are prime examples of what may be termed 'technology leveraging.' The ASTP has initiated over 50 technology projects, many of which were completed and transitioned to users. The objectives are to quickly qualify these higher risk technologies for use on future programs and reduce the risk of inserting these technologies into major systems, and to provide the miniaturized systems that would enable smaller satellites to have significant - rather than limited - capability. Only a few of the advanced technologies are described, the majority of which are applicable to both large and small satellites.

Daniel K. Inouye Solar Telescope: High-resolution observing of the dynamic Sun

NASA Astrophysics Data System (ADS)

Tritschler, A.; Rimmele, T. R.; Berukoff, S.; Casini, R.; Kuhn, J. R.; Lin, H.; Rast, M. P.; McMullin, J. P.; Schmidt, W.; Wöger, F.; DKIST Team

2016-11-01

The 4-m aperture Daniel K. Inouye Solar Telescope (DKIST) formerly known as the Advanced Technology Solar Telescope (ATST) is currently under construction on Haleakalā (Maui, Hawai'i) projected to start operations in 2019. At the time of completion, DKIST will be the largest ground-based solar telescope providing unprecedented resolution and photon collecting power. The DKIST will be equipped with a set of first-light facility-class instruments offering unique imaging, spectroscopic and spectropolarimetric observing opportunities covering the visible to infrared wavelength range. This first-light instrumentation suite will include: a Visible Broadband Imager (VBI) for high-spatial and -temporal resolution imaging of the solar atmosphere; a Visible Spectro-Polarimeter (ViSP) for sensitive and accurate multi-line spectropolarimetry; a Fabry-Pérot based Visible Tunable Filter (VTF) for high-spatial resolution spectropolarimetry; a fiber-fed Diffraction-Limited Near Infra-Red Spectro-Polarimeter (DL-NIRSP) for two-dimensional high-spatial resolution spectropolarimetry (simultaneous spatial and spectral information); and a Cryogenic Near Infra-Red Spectro-Polarimeter (Cryo-NIRSP) for coronal magnetic field measurements and on-disk observations of, e.g., the CO lines at 4.7 μm. We will provide an overview of the DKIST's unique capabilities with strong focus on the first-light instrumentation suite, highlight some of the additional properties supporting observations of transient and dynamic solar phenomena, and touch on some operational strategies and the DKIST critical science plan.

Systems, methods, and software for determining spatially variable distributions of the dielectric properties of a heterogeneous material

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrington, Stephen P.

Systems, methods, and software for measuring the spatially variable relative dielectric permittivity of materials along a linear or otherwise configured sensor element, and more specifically the spatial variability of soil moisture in one dimension as inferred from the dielectric profile of the soil matrix surrounding a linear sensor element. Various methods provided herein combine advances in the processing of time domain reflectometry data with innovations in physical sensing apparatuses. These advancements enable high temporal (and thus spatial) resolution of electrical reflectance continuously along an insulated waveguide that is permanently emplaced in contact with adjacent soils. The spatially resolved reflectance ismore » directly related to impedance changes along the waveguide that are dominated by electrical permittivity contrast due to variations in soil moisture. Various methods described herein are thus able to monitor soil moisture in profile with high spatial resolution.« less

Slope Hazard and Risk Assessment in the Tropics: Malaysia' Experience

NASA Astrophysics Data System (ADS)

Mohamad, Zakaria; Azahari Razak, Khamarrul; Ahmad, Ferdaus; Manap, Mohamad Abdul; Ramli, Zamri; Ahmad, Azhari; Mohamed, Zainab

2015-04-01

The increasing number of geological hazards in Malaysia has often resulted in casualties and extensive devastation with high mitigation cost. Given the destructive capacity and high frequency of disaster, Malaysia has taken a step forward to address the multi-scale landslide risk reduction emphasizing pre-disaster action rather than post-disaster reaction. Slope hazard and risk assessment in a quantitative manner at regional and national scales remains challenging in Malaysia. This paper presents the comprehensive methodology framework and operational needs driven by modern and advanced geospatial technology to address the aforementioned issues in the tropics. The Slope Hazard and Risk Mapping, the first national project in Malaysia utilizing the multi-sensor LIDAR has been critically implemented with the support of multi- and trans-disciplinary partners. The methodological model has been formulated and evaluated given the complexity of risk scenarios in this knowledge driven project. Instability slope problems in the urban, mountainous and tectonic landscape are amongst them, and their spatial information is of crucial for regional landslide assessment. We develop standard procedures with optimal parameterization for susceptibility, hazard and risk assessment in the selected regions. Remarkably, we are aiming at producing an utmost complete landslide inventory in both space and time. With the updated reliable terrain and landscape models, the landslide conditioning factor maps can be accurately derived depending on the landslide types and failure mechanisms which crucial for hazard and risk assessment. We also aim to improve the generation of elements at risk for landslide and promote integrated approaches for a better disaster risk analysis. As a result, a new tool, notably multi-sensor LIDAR technology is a very promising tool for an old geological problem and its derivative data for hazard and risk analysis is an effective preventive measure in Malaysia. Geological, morphological, and physical factors coupled with anthropogenic activities made the spatiotemporal prediction of possible slope failures very challenging. Changing climate and land-use-and-land-cover required a dynamic geo-system approach for assessing multi-hazard in Malaysia and it is still a great challenge to be dealt with. We also critically discussed the capability, limitation and future direction of geo-information tools particularly the active sensors for systematically providing the spatial input towards landslide hazard and possible risk. The cost-and-benefit of developed methods compared to traditional mapping techniques is also elaborated. This paper put forth the critical and practical framework ranging from updating landslide inventory to mitigating landslide risk as an attempt to support the establishment of a comprehensive landslide risk management in Malaysia. The advancement of multistage processing sequence based on airborne-, and ground-based laser remote sensing technology coupling with the sophisticated satellite positioning system, advanced geographical information system and expert knowledge leading to a better understanding of the landslide processes and their dynamics in time and space. Given the state-of-the-art of multi-sensor-LIDAR and complexity of tropical environment, this first landslide project carried out at the national scale provides a better indication and recommendation on the use of modern and advanced mapping technology for assessing tropical landslide geomorphology in an objective, reproducible and quantitative manner.

Advanced life support technology development for the Space Exploration Initiative

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.; Voecks, Gerald E.; Seshan, P. K.

1990-01-01

An overview is presented of NASA's advanced life support technology development strategy for the Space Exploration Initiative. Three basic life support technology areas are discussed in detail: air revitalization, water reclamation, and solid waste management. It is projected that regenerative life support systems will become increasingly more complex as system closure is maximized. Advanced life support technology development will utilize three complementary elements, including the Research and Technology Program, the Regenerative Life Support Program, and the Technology Testbed Validations.

Should laptops be allowed in the classroom? Two viewpoints: viewpoint 1: laptops in classrooms facilitate curricular advancement and promote student learning and viewpoint 2: deconstructing and rethinking the use of laptops in the classroom.

PubMed

Spallek, Heiko; von Bergmann, HsingChi

2014-12-01

This Point/Counterpoint article discusses the pros and cons of deploying one aspect of instructional technology in dental education: the use of laptops in the classroom. Two opposing viewpoints, written by different authors, evaluate the arguments. Viewpoint 1 argues that laptops in classrooms can be a catalyst for rapid curricular advancement and prepare dental graduates for the digital age of dentistry. As dental education is not limited to textual information, but includes skill development in spatial relationships and hands-on training, technology can play a transformative role in students' learning. Carefully implemented instructional technology can enhance student motivation when it transforms students from being the objects of teaching to the subjects of learning. Ubiquitous access to educational material allows for just-in-time learning and can overcome organizational barriers when, for instance, introducing interprofessional education. Viewpoint 2 argues that, in spite of widespread agreement that instructional technology leads to curricular innovation, the notion of the use of laptops in classrooms needs to be deconstructed and rethought when effective learning outcomes are sought. Analyzing the purpose, pedagogy, and learning product while applying lessons learned from K-12 implementation leads to a more complex picture of laptop integration in dental classrooms and forms the basis for questioning the value of such usage. For laptop use to contribute to student learning, rather than simply providing opportunity for students to take notes and access the Internet during class, this viewpoint emphasizes that dental educators need to think carefully about the purpose of this technology and to develop appropriate pedagogical strategies to achieve their objectives. The two viewpoints agree that significant faculty development efforts should precede any introduction of technology into the educational process and that technology alone cannot change education. While the first viewpoint emphasizes the pivotal role of technology in bringing dental education into the contemporary digital world, the second viewpoint focuses on challenges surrounding laptop usage in the classroom including the alignment of instructional methods with learning objectives.

Virtual Technologies to Develop Visual-Spatial Ability in Engineering Students

ERIC Educational Resources Information Center

Roca-González, Cristina; Martin-Gutierrez, Jorge; García-Dominguez, Melchor; Carrodeguas, Mª del Carmen Mato

2017-01-01

The present study assessed a short training experiment to improve spatial abilities using two tools based on virtual technologies: one focused on manipulation of specific geometric virtual pieces, and the other consisting of virtual orienteering game. The two tools can help improve spatial abilities required for many engineering problem-solving…

Demonstration of Airborne Wide Area Assessment Technologies at Pueblo Precision Bombing Ranges, Colorado. Hyperspectral Imaging, Version 2.0

DTIC Science & Technology

2007-09-27

the spatial and spectral resolution ...variety of geological and vegetation mapping efforts, the Hymap sensor offered the best available combination of spectral and spatial resolution , signal... The limitations of the technology currently relate to spatial and spectral resolution and geo- correction accuracy. Secondly, HSI datasets

Recursive algorithms for bias and gain nonuniformity correction in infrared videos.

PubMed

Pipa, Daniel R; da Silva, Eduardo A B; Pagliari, Carla L; Diniz, Paulo S R

2012-12-01

Infrared focal-plane array (IRFPA) detectors suffer from fixed-pattern noise (FPN) that degrades image quality, which is also known as spatial nonuniformity. FPN is still a serious problem, despite recent advances in IRFPA technology. This paper proposes new scene-based correction algorithms for continuous compensation of bias and gain nonuniformity in FPA sensors. The proposed schemes use recursive least-square and affine projection techniques that jointly compensate for both the bias and gain of each image pixel, presenting rapid convergence and robustness to noise. The synthetic and real IRFPA videos experimentally show that the proposed solutions are competitive with the state-of-the-art in FPN reduction, by presenting recovered images with higher fidelity.

Supporting the Growing Needs of the GIS Industry

NASA Technical Reports Server (NTRS)

2003-01-01

Visual Learning Systems, Inc. (VLS), of Missoula, Montana, has developed a commercial software application called Feature Analyst. Feature Analyst was conceived under a Small Business Innovation Research (SBIR) contract with NASA's Stennis Space Center, and through the Montana State University TechLink Center, an organization funded by NASA and the U.S. Department of Defense to link regional companies with Federal laboratories for joint research and technology transfer. The software provides a paradigm shift to automated feature extraction, as it utilizes spectral, spatial, temporal, and ancillary information to model the feature extraction process; presents the ability to remove clutter; incorporates advanced machine learning techniques to supply unparalleled levels of accuracy; and includes an exceedingly simple interface for feature extraction.

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

PubMed Central

Tang, Weixin; Hu, Johnny H.; Liu, David R.

2017-01-01

Programmable sequence-specific genome editing agents such as CRISPR-Cas9 have greatly advanced our ability to manipulate the human genome. Although canonical forms of genome-editing agents and programmable transcriptional regulators are constitutively active, precise temporal and spatial control over genome editing and transcriptional regulation activities would enable the more selective and potentially safer use of these powerful technologies. Here, by incorporating ligand-responsive self-cleaving catalytic RNAs (aptazymes) into guide RNAs, we developed a set of aptazyme-embedded guide RNAs that enable small molecule-controlled nuclease-mediated genome editing and small molecule-controlled base editing, as well as small molecule-dependent transcriptional activation in mammalian cells. PMID:28656978

Field testing of thermal canopy models in a spruce-fir forest

NASA Technical Reports Server (NTRS)

1990-01-01

Recent advances in remote sensing technology allow the use of the thermal infrared region to gain information about vegetative surfaces. Extending existing models to account for thermal radiance transfers within rough forest canopies is of paramount importance. This is so since all processes of interest in the physical climate system and biogeochemical cycles are thermally mediated. Model validation experiments were conducted at a well established boreal forest; northern hardwood forest ecotone research site located in central Maine. Data was collected to allow spatial and temporal validation of thermal models. Emphasis was placed primarily upon enhancing submodels of stomatal behavior, and secondarily upon enhancing boundary layer resistance submodels and accounting for thermal storage in soil and vegetation.

Advanced Platform Systems Technology study. Volume 3: Supporting data

NASA Technical Reports Server (NTRS)

1983-01-01

The overall study effort proceeded from the identification of 106 technology topics to the selection of 5 for detail trade studies. The technical issues and options were evaluated through the trade process. Finally, individual consideration was given to costs and benefits for the technologies identified for advancement. Eight priority technology items were identified for advancement. Supporting data generated during the trade selection and trade study process were presented. Space platform requirements, trade study and cost benefits analysis, and technology advancement planning are advanced. The structured approach used took advantage of a number of forms developed to ensure that a consistent approach was employed by each of the diverse specialists that participated. These forms were an intrinsic part of the study protocol.

Problems In Indoor Mapping and Modelling

NASA Astrophysics Data System (ADS)

Zlatanova, S.; Sithole, G.; Nakagawa, M.; Zhu, Q.

2013-11-01

Research in support of indoor mapping and modelling (IMM) has been active for over thirty years. This research has come in the form of As-Built surveys, Data structuring, Visualisation techniques, Navigation models and so forth. Much of this research is founded on advancements in photogrammetry, computer vision and image analysis, computer graphics, robotics, laser scanning and many others. While IMM used to be the privy of engineers, planners, consultants, contractors, and designers, this is no longer the case as commercial enterprises and individuals are also beginning to apply indoor models in their business process and applications. There are three main reasons for this. Firstly, the last two decades have seen greater use of spatial information by enterprises and the public. Secondly, IMM has been complimented by advancements in mobile computing and internet communications, making it easier than ever to access and interact with spatial information. Thirdly, indoor modelling has been advanced geometrically and semantically, opening doors for developing user-oriented, context-aware applications. This reshaping of the public's attitude and expectations with regards to spatial information has realised new applications and spurred demand for indoor models and the tools to use them. This paper examines the present state of IMM and considers the research areas that deserve attention in the future. In particular the paper considers problems in IMM that are relevant to commercial enterprises and the general public, groups this paper expects will emerge as the greatest users IMM. The subject of indoor modelling and mapping is discussed here in terms of Acquisitions and Sensors, Data Structures and Modelling, Visualisation, Applications, Legal Issues and Standards. Problems are discussed in terms of those that exist and those that are emerging. Existing problems are those that are currently being researched. Emerging problems are those problems or demands that are expected to arise because of social changes, technological advancements, or commercial interests. The motivation of this work is to define a set of research problems that are either being investigated or should be investigated. These will hopefully provide a framework for assessing progress and advances in indoor modelling. The framework will be developed in the form of a problem matrix, detailing existing and emerging problems, their solutions and present best practices. Once the framework is complete it will be published online so that the IMM community can discuss and modify it as necessary. When the framework has reached a steady state an empirical benchmark will be provided to test solutions to posed problems. A yearly evaluation of the problem matrix will follow, the results of which will be published.

Structured Multi-level Data Fusion and Modelling of Heterogeneous Environmental Data for Future Internet Applications

NASA Astrophysics Data System (ADS)

Sabeur, Zoheir; Chakravarthy, Ajay; Bashevoy, Maxim; Modafferi, Stefano

2013-04-01

The rapid increase in environmental observations which are conducted by Small to Medium Enterprise communities and volunteers using affordable in situ sensors at various scales, in addition to the more established observatories set up by environmental and space agencies using airborne and space-borne sensing technologies is generating serious amounts of BIG data at ever increasing speeds. Furthermore, the emergence of Future Internet technologies and the urgent requirements for the deployment of specific enablers for the delivery of processed environmental knowledge in real-time with advanced situation awareness to citizens has reached paramount importance. Specifically, it has become highly critical now to build and provide services which automate the aggregation of data from various sources, while surmounting the semantic gaps, conflicts and heterogeneity in data sources. The early stage aggregation of data will enable the pre-processing of data from multiple sources while reconciling the temporal gaps in measurement time series, and aligning their respective a-synchronicities. This low level type of data fusion process needs to be automated and chained to more advanced level of data fusion services specialising in observation forecasts at spaces where sensing is not deployed; or at time slices where sensing has not taken place yet. As a result, multi-level fusion services are required among the families of specific enablers for monitoring environments and spaces in the Future Internet. These have been intially deployed and piloted in the ongoing ENVIROFI project of the FI-PPP programme [1]. Automated fusion and modelling of in situ and remote sensing data has been set up and the experimentation successfully conducted using RBF networks for the spatial fusion of water quality parameters measurements from satellite and stationary buoys in the Irish Sea. The RBF networks method scales for the spatial data fusion of multiple types of observation sources. This important approach provides a strong basis for the delivery of environmental observations at desired spatial and temporal scales to multiple users with various needs of spatial and temporal resolutions. It has also led to building robust future internet specific enablers on data fusion, which can indeed be used for multiple usage areas above and beyond the environmental domains of the Future Internet. In this paper, data and processing workflow scenarios shall be described. The fucntionalities of the multi-level fusion services shall be demonstrated and made accessible to the wider communities of the Fututre Internet. [1] The Environmental Observation Web and its Service Applications within the Future Internet. ENVIROFI IP. FP7-2011-ICT-IF Pr.No: 284898 http://www.envirofi.eu/

Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

[Technology development as social process: prospects and frontiers of social scientific elucidation of technological advancement].

PubMed

Dierkes, M

1990-05-01

This article provides an overview of the new developments in social scientific technology research which have changed considerably as a result of public debate and reactions to the importance of advancements in technology. The shift in emphasis, away from the effects of technology to its shaping, is described and certain hypotheses and concepts of advancement in the study of the social conditions underlying technical development processes are presented.

Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions

ERIC Educational Resources Information Center

Syed, Mahbubur Rahman, Ed.

2009-01-01

The emerging field of advanced distance education delivers academic courses across time and distance, allowing educators and students to participate in a convenient learning method. "Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions" demonstrates communication technologies, intelligent…

Advanced Technological Education Program: 1995 Awards and Activities.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC. Directorate for Education and Human Resources.

The Advanced Technological Education (ATE) program promotes exemplary improvement in advanced technological education at the national and regional level through support of curriculum development and program improvement at the undergraduate and secondary school levels, especially for technicians being educated for the high performance workplace of…

Research Opportunities in Advanced Aerospace Concepts

NASA Technical Reports Server (NTRS)

Jones, Gregory S.; Bangert, Linda S.; Garber, Donald P.; Huebner, Lawrence D.; McKinley, Robert E.; Sutton, Kenneth; Swanson, Roy C., Jr.; Weinstein, Leonard

2000-01-01

This report is a review of a team effort that focuses on advanced aerospace concepts of the 21st Century. The paper emphasis advanced technologies, rather than cataloging every unusual aircraft that has ever been attempted. To dispel the myth that "aerodynamics is a mature science" an extensive list of "What we cannot do, or do not know" was enumerated. A zeit geist, a feeling for the spirit of the times, was developed, based on existing research goals. Technological drivers and the constraints that might influence these technological developments in a future society were also examined. The present status of aeronautics, space exploration, and non-aerospace applications, both military and commercial, including enabling technologies are discussed. A discussion of non-technological issues affecting advanced concepts research is presented. The benefit of using the study of advanced vehicles as a tool to uncover new directions for technology development is often necessary. An appendix is provided containing examples of advanced vehicle configurations currently of interest.

Energy Efficient Engine program advanced turbofan nacelle definition study

NASA Technical Reports Server (NTRS)

Howe, David C.; Wynosky, T. A.

1985-01-01

Advanced, low drag, nacelle configurations were defined for some of the more promising propulsion systems identified in the earlier Benefit/Cost Study, to assess the benefits associated with these advanced technology nacelles and formulate programs for developing these nacelles and low volume thrust reversers/spoilers to a state of technology readiness in the early 1990's. The study results established the design feasibility of advanced technology, slim line nacelles applicable to advanced technology, high bypass ratio turbofan engines. Design feasibility was also established for two low volume thrust reverse/spoiler concepts that meet or exceed the required effectiveness for these engines. These nacelle and thrust reverse/spoiler designs were shown to be applicable in engines with takeoff thrust sizes ranging from 24,000 to 60,000 pounds. The reduced weight, drag, and cost of the advanced technology nacelle installations relative to current technology nacelles offer a mission fuel burn savings ranging from 3.0 to 4.5 percent and direct operating cost plus interest improvements from 1.6 to 2.2 percent.

Potentials of Advanced Database Technology for Military Information Systems

DTIC Science & Technology

2001-04-01

UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP010866 TITLE: Potentials of Advanced Database Technology for Military... Technology for Military Information Systems Sunil Choennia Ben Bruggemanb a National Aerospace Laboratory, NLR, P.O. Box 90502, 1006 BM Amsterdam...application of advanced information tech- nology, including database technology , as underpin- actions X and Y as dangerous or not? ning is

Technological Ecosystems in Health Informatics: A Brief Review Article.

PubMed

Wu, Zhongmei; Zhang, Xiuxiu; Chen, Ying; Zhang, Yan

2016-09-01

The existing models of information technology in health sciences have full scope of betterment and extension. The high demand pressures, public expectations, advanced platforms all collectively contribute towards hospital environment, which has to be kept in kind while designing of advanced technological ecosystem for information technology. Moreover, for the smooth conduct and operation of information system advanced management avenues are also essential in hospitals. It is the top priority of every hospital to deal with the essential needs of care for patients within the available resources of human and financial outputs. In these situations of high demand, the technological ecosystems in health informatics come in to play and prove its importance and role. The present review article would enlighten all these aspects of these ecosystems in hospital management and health care informatics. We searched the electronic database of MEDLINE, EMBASE, and PubMed for clinical controlled trials, pre-clinical studies reporting utilizaiono of ecosysyem advances in health information technology. The primary outcome of eligible studies included confirmation of importance and role of advances ecosystems in health informatics. It was observed that technological ecosystems are the backbone of health informatics. Advancements in technological ecosystems are essential for proper functioning of health information system in clinical setting.

77 FR 59592 - Visiting Committee on Advanced Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-28

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. [[Page 59593

High angular resolution at LBT

NASA Astrophysics Data System (ADS)

Conrad, A.; Arcidiacono, C.; Bertero, M.; Boccacci, P.; Davies, A. G.; Defrere, D.; de Kleer, K.; De Pater, I.; Hinz, P.; Hofmann, K. H.; La Camera, A.; Leisenring, J.; Kürster, M.; Rathbun, J. A.; Schertl, D.; Skemer, A.; Skrutskie, M.; Spencer, J. R.; Veillet, C.; Weigelt, G.; Woodward, C. E.

2015-12-01

High angular resolution from ground-based observatories stands as a key technology for advancing planetary science. In the window between the angular resolution achievable with 8-10 meter class telescopes, and the 23-to-40 meter giants of the future, LBT provides a glimpse of what the next generation of instruments providing higher angular resolution will provide. We present first ever resolved images of an Io eruption site taken from the ground, images of Io's Loki Patera taken with Fizeau imaging at the 22.8 meter LBT [Conrad, et al., AJ, 2015]. We will also present preliminary analysis of two data sets acquired during the 2015 opposition: L-band fringes at Kurdalagon and an occultation of Loki and Pele by Europa (see figure). The light curves from this occultation will yield an order of magnitude improvement in spatial resolution along the path of ingress and egress. We will conclude by providing an overview of the overall benefit of recent and future advances in angular resolution for planetary science.

Scan-o-matic: High-Resolution Microbial Phenomics at a Massive Scale

PubMed Central

Zackrisson, Martin; Hallin, Johan; Ottosson, Lars-Göran; Dahl, Peter; Fernandez-Parada, Esteban; Ländström, Erik; Fernandez-Ricaud, Luciano; Kaferle, Petra; Skyman, Andreas; Stenberg, Simon; Omholt, Stig; Petrovič, Uroš; Warringer, Jonas; Blomberg, Anders

2016-01-01

The capacity to map traits over large cohorts of individuals—phenomics—lags far behind the explosive development in genomics. For microbes, the estimation of growth is the key phenotype because of its link to fitness. We introduce an automated microbial phenomics framework that delivers accurate, precise, and highly resolved growth phenotypes at an unprecedented scale. Advancements were achieved through the introduction of transmissive scanning hardware and software technology, frequent acquisition of exact colony population size measurements, extraction of population growth rates from growth curves, and removal of spatial bias by reference-surface normalization. Our prototype arrangement automatically records and analyzes close to 100,000 growth curves in parallel. We demonstrate the power of the approach by extending and nuancing the known salt-defense biology in baker’s yeast. The introduced framework represents a major advance in microbial phenomics by providing high-quality data for extensive cohorts of individuals and generating well-populated and standardized phenomics databases PMID:27371952

Non-Markovian quantum processes: Complete framework and efficient characterization

NASA Astrophysics Data System (ADS)

Pollock, Felix A.; Rodríguez-Rosario, César; Frauenheim, Thomas; Paternostro, Mauro; Modi, Kavan

2018-01-01

Currently, there is no systematic way to describe a quantum process with memory solely in terms of experimentally accessible quantities. However, recent technological advances mean we have control over systems at scales where memory effects are non-negligible. The lack of such an operational description has hindered advances in understanding physical, chemical, and biological processes, where often unjustified theoretical assumptions are made to render a dynamical description tractable. This has led to theories plagued with unphysical results and no consensus on what a quantum Markov (memoryless) process is. Here, we develop a universal framework to characterize arbitrary non-Markovian quantum processes. We show how a multitime non-Markovian process can be reconstructed experimentally, and that it has a natural representation as a many-body quantum state, where temporal correlations are mapped to spatial ones. Moreover, this state is expected to have an efficient matrix-product-operator form in many cases. Our framework constitutes a systematic tool for the effective description of memory-bearing open-system evolutions.

The Advanced Telescope for High Energy Astrophysics

NASA Astrophysics Data System (ADS)

Guainazzi, Matteo

2017-08-01

Athena (the Advanced Telescope for High Energy Astrophysics) is a next generation X-ray observatory currently under study by ESA for launch in 2028. Athena is designed to address the Hot and Energetic Universe science theme, which addresses two key questions: 1) How did ordinary matter evolve into the large scale structures we see today? 2) How do black holes grow and shape the Universe. To address these topics Athena employs an innovative X-ray telescope based on Silicon Pore Optics technology to deliver extremely light weight and high throughput, while retaining excellent angular resolution. The mirror can be adjusted to focus onto one of two focal place instruments: the X-ray Integral Field Unit (X-IFU) which provides spatially-resolved, high resolution spectroscopy, and the Wide Field Imager (WFI) which provides spectral imaging over a large field of view, as well as high time resolution and count rate tolerance. Athena is currently in Phase A and the study status will be reviewed, along with the scientific motivations behind the mission.

Electroencephalographic imaging of higher brain function

NASA Technical Reports Server (NTRS)

Gevins, A.; Smith, M. E.; McEvoy, L. K.; Leong, H.; Le, J.

1999-01-01

High temporal resolution is necessary to resolve the rapidly changing patterns of brain activity that underlie mental function. Electroencephalography (EEG) provides temporal resolution in the millisecond range. However, traditional EEG technology and practice provide insufficient spatial detail to identify relationships between brain electrical events and structures and functions visualized by magnetic resonance imaging or positron emission tomography. Recent advances help to overcome this problem by recording EEGs from more electrodes, by registering EEG data with anatomical images, and by correcting the distortion caused by volume conduction of EEG signals through the skull and scalp. In addition, statistical measurements of sub-second interdependences between EEG time-series recorded from different locations can help to generate hypotheses about the instantaneous functional networks that form between different cortical regions during perception, thought and action. Example applications are presented from studies of language, attention and working memory. Along with its unique ability to monitor brain function as people perform everyday activities in the real world, these advances make modern EEG an invaluable complement to other functional neuroimaging modalities.

Dielectric Metasurface Optics: A New Platform for Compact Optical Sensing

NASA Astrophysics Data System (ADS)

Colburn, Shane

Metasurfaces, the 2D analogue of bulk metamaterials, show incredible promise for achieving nanoscale optical components that could support the growing infrastructure for the Internet of Things (IoT) and future sensing technologies. Consisting of quasiperiodic arrays of subwavelength scattering elements, metasurfaces apply spatial transfer functions to incident wavefronts, abruptly altering properties of light over a wavelength-scale thickness. By appropriately patterning scatterers on the structure, arbitrary functions can be implemented up to the limitations on the scattering properties of the particular elements. This thesis details theoretical work and simulations on the design of scattering elements with advanced capabilities for dielectric metasurfaces, showing polarization-multiplexed operation in the visible regime, multiwavelength capability in the visible regime along with a general methodology for eliminating chromatic aberrations at discrete wavelengths, and compact and tunable elements for 1550 nm operation inspired by an asymmetric Fabry-Perot cavity. These advancements enhance the capabilities of metasurfaces in the visible regime and help move toward the goal of achieving reconfigurable metasurfaces for compact and efficient optical sensors.

An Overview and Status of NASA's Radioisotope Power Conversion Technology NRA

NASA Technical Reports Server (NTRS)

Anderson, David J.; Wong, Wayne A.; Tuttle, Karen L.

2005-01-01

NASA's Advanced Radioisotope Power Systems (RPS) development program is developing next generation radioisotope power conversion technologies that will enable future missions that have requirements that can not be met by either photovoltaic systems or by current Radioisotope Power System (RPS) technology. The Advanced Power Conversion Research and Technology project of the Advanced RPS development program is funding research and technology activities through the NASA Research Announcement (NRA) 02- OSS-01, "Research Opportunities in Space Science 2002" entitled "Radioisotope Power Conversion Technology" (RPCT), 13 August 2002. The objective of the RPCT NRA is to advance the development of radioisotope power conversion technologies to provide significant improvements over the state-of-practice General Purpose Heat Source/Radioisotope Thermoelectric Generator by providing significantly higher efficiency to reduce the number of radioisotope fuel modules, and increase specific power (watts/kilogram). Other Advanced RPS goals include safety, long-life, reliability, scalability, multi-mission capability, resistance to radiation, and minimal interference with the scientific payload. These advances would enable a factor of 2 to 4 decrease in the amount of fuel required to generate electrical power. The RPCT NRA selected advanced RPS power conversion technology research and development proposals in the following three areas: innovative RPS power conversion research, RPS power conversion technology development in a nominal 100We scale; and, milliwatt/multi-watt RPS (mWRPS) power conversion research. Ten RPCT NRA contracts were awarded in 2003 in the areas of Brayton, Stirling, thermoelectric (TE), and thermophotovoltaic (TPV) power conversion technologies. This paper will provide an overview of the RPCT NRA, and a brief summary of accomplishments over the first 18 months but focusing on advancements made over the last 6 months.

Benefits of Integration of Aerojet Rocketdyne and RTI Advanced Gasification Technologies for Hydrogen-Rich Syngas Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, Vijay; Denton, David; SHarma, Pradeep

The key objective for this project was to evaluate the potential to achieve substantial reductions in the production cost of H 2-rich syngas via coal gasification with near-zero emissions due to the cumulative and synergistic benefits realized when multiple advanced technologies are integrated into the overall conversion process. In this project, Aerojet Rocketdyne’s (AR’s) advanced gasification technology (currently being offered as R-GAS™) and RTI International’s (RTI’s) advanced warm syngas cleanup technologies were evaluated via a number of comparative techno-economic case studies. AR’s advanced gasification technology consists of a dry solids pump and a compact gasifier system. Based on the uniquemore » design of this gasifier, it has been shown to reduce the capital cost of the gasification block by between 40 and 50%. At the start of this project, actual experimental work had been demonstrated through pilot plant systems for both the gasifier and dry solids pump. RTI’s advanced warm syngas cleanup technologies consist primarily of RTI’s Warm Gas Desulfurization Process (WDP) technology, which effectively allows decoupling of the sulfur and CO 2 removal allowing for more flexibility in the selection of the CO 2 removal technology, plus associated advanced technologies for direct sulfur recovery and water gas shift (WGS). WDP has been demonstrated at pre-commercial scale using an activated amine carbon dioxide recovery process which would not have been possible if a majority of the sulfur had not been removed from the syngas by WDP. This pre-commercial demonstration of RTI’s advanced warm syngas cleanup system was conducted in parallel to the activities on this project. The technical data and cost information from this pre-commercial demonstration were extensively used in this project during the techno-economic analysis. With this project, both of RTI’s advanced WGS technologies were investigated. Because RT’s advanced fixed-bed WGS (AFWGS) process was successfully implemented in the WDP pre-commercial demonstration test mentioned above, this technology was used as part of RTI’s advanced warm syngas technology package for the techno-economic analyses for this project. RTI’s advanced transport-reactor-based WGS (ATWGS) process was still conceptual at the start of this project, but one of the tasks for this project was to evaluate the technical feasibility of this technology. In each of the three application-based comparison studies conducted as part of this project, the reference case was based on an existing Department of Energy National Energy Technology Laboratory (DOE/NETL) system study. Each of these references cases used existing commercial technology and the system resulted in > 90% carbon capture. In the comparison studies for the use of the hydrogen-rich syngas generated in either an Integrated Gasification Combined Cycle (IGCC) or a Coal-to-Methanol (CTM) plant, the comparison cases consisted of the reference case, a case with the integration of each individual advanced technology (either AR or RTI), and finally a case with the integration of all the advanced technologies (AR and RTI combined). In the Coal-to-Liquids (CTL) comparison study, the comparison study consisted of only three cases, which included a reference case, a case with just RTI’s advanced syngas cleaning technology, and a case with AR’s and RTI’s advanced technologies. The results from these comparison studies showed that the integration of the advanced technologies did result in substantial benefits, and by far the greatest benefits were achieved for cases integrating all the advanced technologies. For the IGCC study, the fully integrated case resulted in a 1.4% net efficiency improvement, an 18% reduction in capital cost per kW of capacity, a 12% reduction in the operating cost per kWh, and a 75–79% reduction in sulfur emissions. For the CTM case, the fully integrated plant resulted in a 22% reduction in capital cost, a 13% reduction in operating costs, a > 99% net reduction in sulfur emissions, and a reduction of 13–15% in CO 2 emissions. Because the capital cost represents over 60% of the methanol Required Selling Price (RSP), the significant reduction in the capital cost for the advanced technology case resulted in an 18% reduction in methanol RSP. For the CTL case, the fully integrated plant resulted in a 16% reduction in capital cost, which represented a 13% reduction in diesel RSP. Finally, the technical feasibility analysis of RTI’s ATWGS process demonstrated that a fluid-bed catalyst with sufficient attrition resistance and WGS activity could be made and that the process achieved about a 24% reduction in capital cost compared to a conventional fixed-bed commercial process.« less

Advanced Measurement Systems Available to PIWG Members

NASA Technical Reports Server (NTRS)

Anderson, Robert; Lei, Jih-Fen (Technical Monitor)

2002-01-01

It was developed advanced measurement technologies to meet NASA goals: reduce design cycle time, reduce emission, reduce testing time, increase safety. The technology are saving money. This technology are available now for technology transfer: optical diagnostics, the film technology and MEMS devices.

Modeling of advanced technology vehicles

DOT National Transportation Integrated Search

2003-09-01

The characterization of some types of "advanced technology vehicles" may help to understand policies that are strongly either explicitly or implicitly technology-dependent. Recent models attempt to characterize such technologies in terms of fuel econ...

Solar sail science mission applications and advancement

NASA Astrophysics Data System (ADS)

Macdonald, Malcolm; McInnes, Colin

2011-12-01

Solar sailing has long been envisaged as an enabling or disruptive technology. The promise of open-ended missions allows consideration of radically new trajectories and the delivery of spacecraft to previously unreachable or unsustainable observation outposts. A mission catalogue is presented of an extensive range of potential solar sail applications, allowing identification of the key features of missions which are enabled, or significantly enhance, through solar sail propulsion. Through these considerations a solar sail application-pull technology development roadmap is established, using each mission as a technology stepping-stone to the next. Having identified and developed a solar sail application-pull technology development roadmap, this is incorporated into a new vision for solar sailing. The development of new technologies, especially for space applications, is high-risk. The advancement difficulty of low technology readiness level research is typically underestimated due to a lack of recognition of the advancement degree of difficulty scale. Recognising the currently low technology readiness level of traditional solar sailing concepts, along with their high advancement degree of difficulty and a lack of near-term applications a new vision for solar sailing is presented which increases the technology readiness level and reduces the advancement degree of difficulty of solar sailing. Just as the basic principles of solar sailing are not new, they have also been long proven and utilised in spacecraft as a low-risk, high-return limited-capability propulsion system. It is therefore proposed that this significant heritage be used to enable rapid, near-term solar sail future advancement through coupling currently mature solar sail, and other, technologies with current solar sail technology developments. As such the near-term technology readiness level of traditional solar sailing is increased, while simultaneously reducing the advancement degree of difficulty along the solar sail application-pull technology development roadmap.

49 CFR 535.7 - Averaging, banking, and trading (ABT) program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... averaging set. With the exception of FCC earned for advance technologies as further clarified below, a... transactions. Traded FCC, other than advanced technology credits, may be used by a manufacturer only within the... fleet includes conventional vehicles (gasoline, diesel and alternative fuel) and advanced technology...

49 CFR 535.7 - Averaging, banking, and trading (ABT) program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... averaging set. With the exception of FCC earned for advance technologies as further clarified below, a... transactions. Traded FCC, other than advanced technology credits, may be used by a manufacturer only within the... fleet includes conventional vehicles (gasoline, diesel and alternative fuel) and advanced technology...

Advances for Studying Clonal Evolution in Cancer

PubMed Central

Raphael, Benjamin J.; Chen, Feng; Wendl, Michael C.

2013-01-01

The “clonal evolution” model of cancer emerged and “evolved” amid ongoing advances in technology, especially in recent years during which next generation sequencing instruments have provided ever higher resolution pictures of the genetic changes in cancer cells and heterogeneity in tumors. It has become increasingly clear that clonal evolution is not a single sequential process, but instead frequently involves simultaneous evolution of multiple subclones that co-exist because they are of similar fitness or are spatially separated. Co-evolution of subclones also occurs when they complement each other’s survival advantages. Recent studies have also shown that clonal evolution is highly heterogeneous: different individual tumors of the same type may undergo very different paths of clonal evolution. New methodological advancements, including deep digital sequencing of a mixed tumor population, single cell sequencing, and the development of more sophisticated computational tools, will continue to shape and reshape the models of clonal evolution. In turn, these will provide both an improved framework for the understanding of cancer progression and a guide for treatment strategies aimed at the elimination of all, rather than just some, of the cancer cells within a patient. PMID:23353056

Advances for studying clonal evolution in cancer.

PubMed

Ding, Li; Raphael, Benjamin J; Chen, Feng; Wendl, Michael C

2013-11-01

The "clonal evolution" model of cancer emerged and "evolved" amid ongoing advances in technology, especially in recent years during which next generation sequencing instruments have provided ever higher resolution pictures of the genetic changes in cancer cells and heterogeneity in tumors. It has become increasingly clear that clonal evolution is not a single sequential process, but instead frequently involves simultaneous evolution of multiple subclones that co-exist because they are of similar fitness or are spatially separated. Co-evolution of subclones also occurs when they complement each other's survival advantages. Recent studies have also shown that clonal evolution is highly heterogeneous: different individual tumors of the same type may undergo very different paths of clonal evolution. New methodological advancements, including deep digital sequencing of a mixed tumor population, single cell sequencing, and the development of more sophisticated computational tools, will continue to shape and reshape the models of clonal evolution. In turn, these will provide both an improved framework for the understanding of cancer progression and a guide for treatment strategies aimed at the elimination of all, rather than just some, of the cancer cells within a patient. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Advances in biologically inspired on/near sensor processing

NASA Astrophysics Data System (ADS)

McCarley, Paul L.

1999-07-01

As electro-optic sensors increase in size and frame rate, the data transfer and digital processing resource requirements also increase. In many missions, the spatial area of interest is but a small fraction of the available field of view. Choosing the right region of interest, however, is a challenge and still requires an enormous amount of downstream digital processing resources. In order to filter this ever-increasing amount of data, we look at how nature solves the problem. The Advanced Guidance Division of the Munitions Directorate, Air Force Research Laboratory at Elgin AFB, Florida, has been pursuing research in the are of advanced sensor and image processing concepts based on biologically inspired sensory information processing. A summary of two 'neuromorphic' processing efforts will be presented along with a seeker system concept utilizing this innovative technology. The Neuroseek program is developing a 256 X 256 2-color dual band IRFPA coupled to an optimized silicon CMOS read-out and processing integrated circuit that provides simultaneous full-frame imaging in MWIR/LWIR wavebands along with built-in biologically inspired sensor image processing functions. Concepts and requirements for future such efforts will also be discussed.

Advances in Spectral-Spatial Classification of Hyperspectral Images

NASA Technical Reports Server (NTRS)

Fauvel, Mathieu; Tarabalka, Yuliya; Benediktsson, Jon Atli; Chanussot, Jocelyn; Tilton, James C.

2012-01-01

Recent advances in spectral-spatial classification of hyperspectral images are presented in this paper. Several techniques are investigated for combining both spatial and spectral information. Spatial information is extracted at the object (set of pixels) level rather than at the conventional pixel level. Mathematical morphology is first used to derive the morphological profile of the image, which includes characteristics about the size, orientation and contrast of the spatial structures present in the image. Then the morphological neighborhood is defined and used to derive additional features for classification. Classification is performed with support vector machines using the available spectral information and the extracted spatial information. Spatial post-processing is next investigated to build more homogeneous and spatially consistent thematic maps. To that end, three presegmentation techniques are applied to define regions that are used to regularize the preliminary pixel-wise thematic map. Finally, a multiple classifier system is defined to produce relevant markers that are exploited to segment the hyperspectral image with the minimum spanning forest algorithm. Experimental results conducted on three real hyperspectral images with different spatial and spectral resolutions and corresponding to various contexts are presented. They highlight the importance of spectral-spatial strategies for the accurate classification of hyperspectral images and validate the proposed methods.

Implications of advanced vehicle technologies for older drivers.

PubMed

Molnar, Lisa J; Eby, David W

2017-09-01

Advances are being made in vehicle technologies that may help older adults compensate for some of the declines in abilities associated with aging. These advances hold promise for increasing vehicle safety, reducing injuries, and making the driving task more comfortable. However, important research gaps remain with regard to how various advanced technologies impact the safety of older drivers, as well as older drivers' perceptions about these technologies. This special issue contains seven original contributions that address these issues. Specific topics include the: congruence of design guidelines with the needs and abilities of older drivers, transfer of control between automated and manual driving, use of in-vehicle monitoring technology, motivations for technology use and assigned meanings, technology valuation, and effects on driving behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Emergence and Impact of Intelligent Machines. Chapter 10

NASA Technical Reports Server (NTRS)

Kurzweil, Raymond

2007-01-01

The following issues are addressed in this essay: a) Models of Technology Trends: A discussion of why nanotechnology and related advanced technologies are inevitable. The underlying technologies are deeply integrated into our society and are advancing on many diverse fronts; and b) The Economic Imperatives of the Law of Accelerating Returns: The exponential advance of technology, including the accelerating miniaturization of technology, is driven by economic imperative, and, in turn, has a pervasive impact on the economy.

Survey of cogeneration: Advanced cogeneration research study

NASA Technical Reports Server (NTRS)

Slonski, M. L.

1983-01-01

The consumption of electricity, natural gas, or fuel oil was surveyed. The potential electricity that could be generated in the SCE service territory using cogeneration technology was estimated. It was found that an estimated 3700 MWe could potentially be generated in Southern California using cogenerated technology. It is suggested that current technology could provide 2600 MWe and advanced technology could provide 1100 MWe. Approximately 1600 MWt is considered not feasible to produce electricity with either current or advanced cogeneration technology.

Abstract ID: 242 Simulation of a Fast Timing Micro-Pattern Gaseous Detector for TOF-PET.

PubMed

Radogna, Raffaella; Verwilligen, Piet

2018-01-01

Micro-Pattern Gas Detectors (MPGDs) are a new generation of gaseous detectors that have been developed thanks to advances in micro-structure technology. The main features of the MPGDs are: high rate capability (>50 MHz/cm 2 ); excellent spatial resolution (down to 50 μm); good time resolution (down to 3 ns); reduced radiation length, affordable costs, and possible flexible geometries. A new detector layout has been recently proposed that aims at combining both the high spatial resolution and high rate capability (100 MHz/cm 2 ) of the current state-of-the-art MPGDs with a high time resolution. This new type of MPGD is named the Fast Timing MPGD (FTM) detector [1,2]. The FTM developed for detecting charged particles can potentially reach sub-millimeter spatial resolution and 100 ps time resolution. This contribution introduces a Fast Timing MPGD technology optimized to detect photons, as an innovative PET imaging detector concept and emphases the importance of full detector simulation to guide the design of the detector geometry. The design and development of a new FTM, combining excellent time and spatial resolution, while exploiting the advantages of a reasonable energy resolution, will be a boost for the design of affordable TOF-PET scanner with improved image contrast. The use of such an affordable gas detector allows to instrument large areas in a cost-effective way, and to increase in image contrast for shorter scanning times (lowering the risk for the patient) and better diagnosis of the disease. In this report a dedicated simulation study is performed to optimize the detector design in the contest of the INFN project MPGD-Fatima. Results are obtained with ANSYS, COMSOL, GARFIELD++ and GEANT4 simulation tools. The final detector layout will be trade-off between fast time and good energy resolution. Copyright © 2017.

Components of spatial information management in wildlife ecology: Software for statistical and modeling analysis [Chapter 14

Treesearch

Hawthorne L. Beyer; Jeff Jenness; Samuel A. Cushman

2010-01-01

Spatial information systems (SIS) is a term that describes a wide diversity of concepts, techniques, and technologies related to the capture, management, display and analysis of spatial information. It encompasses technologies such as geographic information systems (GIS), global positioning systems (GPS), remote sensing, and relational database management systems (...

Advanced Power Technology Development Activities for Small Satellite Applications

NASA Technical Reports Server (NTRS)

Piszczor, Michael F.; Landis, Geoffrey A.; Miller, Thomas B.; Taylor, Linda M.; Hernandez-Lugo, Dionne; Raffaelle, Ryne; Landi, Brian; Hubbard, Seth; Schauerman, Christopher; Ganter, Mathew;

Technology in TESOL.

ERIC Educational Resources Information Center

TESOL Journal, 1993

1993-01-01

This special issue is devoted to the theme of advancing technology in the teaching of English to speakers of other languages (TESOL). Articles include: "Technology in TESOL" (Richard Orem, Cynthia Holliday); TESOL Technology: Imposition or Opportunity?" (Simon Murison-Bowie); "A Review of Advanced Technologies for L2…

Adaptive Structures Programs for the Strategic Defense Initiative Organization

DTIC Science & Technology

1992-01-01

Advanced Control Technology Experiment ( ACTEX ) Modular Control Patch High Frequency Passive Damping Strut Development Optional PZT Passive...on this space test bed in FY95. The Advanced Control Technology Experiment ( ACTEX ) will demonstrate many of the adaptive structures technologies...Accelerometer Bi-ax Accelerometer Smart Strut Figure 7. Schematic of Advanced Control Technology Experiment ( ACTEX ) 6-28-91-2M 1-6-92-5M PZ Stack

Application of GIS Rapid Mapping Technology in Disaster Monitoring

NASA Astrophysics Data System (ADS)

Wang, Z.; Tu, J.; Liu, G.; Zhao, Q.

2018-04-01

With the rapid development of GIS and RS technology, especially in recent years, GIS technology and its software functions have been increasingly mature and enhanced. And with the rapid development of mathematical statistical tools for spatial modeling and simulation, has promoted the widespread application and popularization of quantization in the field of geology. Based on the investigation of field disaster and the construction of spatial database, this paper uses remote sensing image, DEM and GIS technology to obtain the data information of disaster vulnerability analysis, and makes use of the information model to carry out disaster risk assessment mapping.Using ArcGIS software and its spatial data modeling method, the basic data information of the disaster risk mapping process was acquired and processed, and the spatial data simulation tool was used to map the disaster rapidly.

Electrification Futures Study Technology Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jadun, Paige; McMillan, Colin; Steinberg, Daniel

This data supplements the "Electrification Futures Study: End-Use Electric Technology Cost and Performance Projections through 2050" report. The data included here consist of the cost and performance estimates for electric end-use technologies developed for the three sensitivity cases in the Electrification Futures Study: Slow Advancement, Moderate Advancement, and Rapid Advancement.

Advanced Education and Technology Business Plan, 2009-12

ERIC Educational Resources Information Center

Alberta Advanced Education and Technology, 2009

2009-01-01

The Ministry of Advanced Education and Technology consists of the following entities for budget purposes: Department of Advanced Education and Technology, the Access to the Future Fund, Alberta Enterprise Corporation, Alberta Research Council Inc., and iCORE Inc. Achieving the Ministry's goals involves the work and coordination of many…

40 CFR 86.1866-12 - CO2 credits for advanced technology vehicles.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 20 2013-07-01 2013-07-01 false CO2 credits for advanced technology vehicles. 86.1866-12 Section 86.1866-12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... advanced technology vehicles. (a) Electric vehicles, plug-in hybrid electric vehicles, and fuel cell...

Advanced Technological Education: An Overview and Profile of 11 National Centers.

ERIC Educational Resources Information Center

Maricopa County Community Coll. District, Phoenix, AZ.

This booklet describes the Advanced Technological Education (ATE) program sponsored by the National Science Foundation (NSF). The ATE encourages improvements in advanced technological education at the national and regional levels using curriculum development and program improvement at the undergraduate and secondary school levels. The ATE not only…

Technology Tools to Support Reading in the Digital Age

ERIC Educational Resources Information Center

Biancarosa, Gina; Griffiths, Gina G.

2012-01-01

Advances in digital technologies are dramatically altering the texts and tools available to teachers and students. These technological advances have created excitement among many for their potential to be used as instructional tools for literacy education. Yet with the promise of these advances come issues that can exacerbate the literacy…

49 CFR 535.7 - Averaging, banking, and trading (ABT) program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... averaging set. With the exception of FCC earned for advance technologies as further clarified below, a... advanced technology credits, may be used only within the averaging set in which they were generated. (b... (gasoline, diesel and alternative fuel) and advanced technology vehicles (hybrids with regenerative braking...

A Relationship with Great Chemistry

ERIC Educational Resources Information Center

Gibbs, Hope J.

2005-01-01

More than a decade ago, the United States Congress passed the Scientific and Advanced Technology Act, which authorized the Advanced Technological Education program (ATE). Through ATE, the National Science Foundation (NSF) was directed to develop models aimed at two-year colleges of advanced technological education in order to expand the nation's…

Baseline Study Methodology for Future Phases of Research on Nuclear Power Plant Control Room Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Le Blanc, Katya Lee; Bower, Gordon Ross; Hill, Rachael Ann

In order to provide a basis for industry adoption of advanced technologies, the Control Room Upgrades Benefits Research Project will investigate the benefits of including advanced technologies as part of control room modernization This report describes the background, methodology, and research plan for the first in a series of full-scale studies to test the effects of advanced technology in NPP control rooms. This study will test the effect of Advanced Overview Displays in the partner Utility’s control room simulator

Advancing automation and robotics technology for the space station and the US economy

NASA Technical Reports Server (NTRS)

Cohen, A.

1985-01-01

In response to Public Law 98-371, dated July 18, 1984, the NASA Advanced Technology Advisory Committee has studied automation and rebotics for use in the space station. The Executive Overview, Volume 1 presents the major findings of the study and recommends to NASA principles for advancing automation and robotics technologies for the benefit of the space station and of the U.S. economy in general. As a result of its study, the Advanced Technology Advisory Committee believes that a key element of technology for the space station is extensive use of advanced general-purpose automation and robotics. These systems could provide the United States with important new methods of generating and exploiting space knowledge in commercial enterprises and thereby help preserve U.S. leadership in space.

Advanced imaging research and development at DARPA

NASA Astrophysics Data System (ADS)

Dhar, Nibir K.; Dat, Ravi

2012-06-01

Advances in imaging technology have huge impact on our daily lives. Innovations in optics, focal plane arrays (FPA), microelectronics and computation have revolutionized camera design. As a result, new approaches to camera design and low cost manufacturing is now possible. These advances are clearly evident in visible wavelength band due to pixel scaling, improvements in silicon material and CMOS technology. CMOS cameras are available in cell phones and many other consumer products. Advances in infrared imaging technology have been slow due to market volume and many technological barriers in detector materials, optics and fundamental limits imposed by the scaling laws of optics. There is of course much room for improvements in both, visible and infrared imaging technology. This paper highlights various technology development projects at DARPA to advance the imaging technology for both, visible and infrared. Challenges and potentials solutions are highlighted in areas related to wide field-of-view camera design, small pitch pixel, broadband and multiband detectors and focal plane arrays.

Advanced sensors technology survey

NASA Technical Reports Server (NTRS)

Cooper, Tommy G.; Costello, David J.; Davis, Jerry G.; Horst, Richard L.; Lessard, Charles S.; Peel, H. Herbert; Tolliver, Robert

1992-01-01

This project assesses the state-of-the-art in advanced or 'smart' sensors technology for NASA Life Sciences research applications with an emphasis on those sensors with potential applications on the space station freedom (SSF). The objectives are: (1) to conduct literature reviews on relevant advanced sensor technology; (2) to interview various scientists and engineers in industry, academia, and government who are knowledgeable on this topic; (3) to provide viewpoints and opinions regarding the potential applications of this technology on the SSF; and (4) to provide summary charts of relevant technologies and centers where these technologies are being developed.

Solar Cell and Array Technology Development for NASA Solar Electric Propulsion Missions

NASA Technical Reports Server (NTRS)

Piszczor, Michael; McNatt, Jeremiah; Mercer, Carolyn; Kerslake, Tom; Pappa, Richard

2012-01-01

NASA is currently developing advanced solar cell and solar array technologies to support future exploration activities. These advanced photovoltaic technology development efforts are needed to enable very large (multi-hundred kilowatt) power systems that must be compatible with solar electric propulsion (SEP) missions. The technology being developed must address a wide variety of requirements and cover the necessary advances in solar cell, blanket integration, and large solar array structures that are needed for this class of missions. Th is paper will summarize NASA's plans for high power SEP missions, initi al mission studies and power system requirements, plans for advanced photovoltaic technology development, and the status of specific cell and array technology development and testing that have already been conducted.

Toyota Prius Plug-In HEV: A Plug-In Hybrid Electric Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This fact sheet highlights the Toyota Prius plug-in HEV, a plug-in hybrid electric car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In partnership with the University of Colorado, NREL uses the vehicle for grid-integration studies and for testing new hardware and charge-management algorithms. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, andmore » emerging technologies.« less

Aerospace Materials Process Modelling

DTIC Science & Technology

1988-08-01

development of advanced technologies for the fabrication of close-tolerance parts, in conjunction with the development of advanced materials, plays a key...1883. 17. Gegel, H. L., et al., "Materials Modeling and Intrinsic Workability for Simulation of Bulk Deformiti6n," Advanced Technology of Plasticity, Vol...process in the last three decades. As a result of technological advances gained in aerospace industry there has been an increasing demand for the

An electromagnetic noncontacting sensor for thickness measurement in a dispersive medium

NASA Technical Reports Server (NTRS)

Chufo, Robert L.

1994-01-01

This paper describes a general purpose imaging technology developed by the U.S. Bureau of Mines (USBM) that, when fully implemented, will solve the general problem of 'seeing into the earth.' A first-generation radar coal thickness sensor, the RCTS-1, has been developed and field-tested in both underground and highwall mines. The noncontacting electromagnetic technique uses spatial modulation created by moving a simple sensor antenna in a direction along each axis to be measured while the complex reflection coefficient is measured at multiple frequencies over a two-to-one bandwidth. The antenna motion imparts spatial modulation to the data that enables signal processing to solve the problems of media, target, and antenna dispersion. Knowledge of the dielectric constant of the media is not necessary because the electrical properties of the media are determined automatically along with the distance to the target and thickness of each layer of the target. The sensor was developed as a navigation guidance sensor to accurately detect the coal/noncoal interface required for the USBM computer-assisted mining machine program. Other mining applications include the location of rock fractures, water-filled voids, and abandoned gas wells. These hazards can be detected in advance of the mining operation. This initiating technology is being expanded into a full three-dimensional (3-D) imaging system that will have applications in both the underground and surface environment.

Solar Electric and Chemical Propulsion Technology Applications to a Titan Orbiter/Lander Mission

NASA Technical Reports Server (NTRS)

Cupples, Michael

2007-01-01

Several advanced propulsion technology options were assessed for a conceptual Titan Orbiter/Lander mission. For convenience of presentation, the mission was broken into two phases: interplanetary and Titan capture. The interplanetary phase of the mission was evaluated for an advanced Solar Electric Propulsion System (SEPS), while the Titan capture phase was evaluated for state-of-art chemical propulsion (NTO/Hydrazine), three advanced chemical propulsion options (LOX/Hydrazine, Fluorine/Hydrazine, high Isp mono-propellant), and advanced tank technologies. Hence, this study was referred to as a SEPS/Chemical based option. The SEPS/Chemical study results were briefly compared to a 2002 NASA study that included two general propulsion options for the same conceptual mission: an all propulsive based mission and a SEPS/Aerocapture based mission. The SEP/Chemical study assumed identical science payload as the 2002 NASA study science payload. The SEPS/Chemical study results indicated that the Titan mission was feasible for a medium launch vehicle, an interplanetary transfer time of approximately 8 years, an advanced SEPS (30 kW), and current chemical engine technology (yet with advanced tanks) for the Titan capture. The 2002 NASA study showed the feasibility of the mission based on a somewhat smaller medium launch vehicle, an interplanetary transfer time of approximately 5.9 years, an advanced SEPS (24 kW), and advanced Aerocapture based propulsion technology for the Titan capture. Further comparisons and study results were presented for the advanced chemical and advanced tank technologies.

Beyond the Baseline: Proceedings of the Space Station Evolution Symposium. Volume 2, Part 2; Space Station Freedom Advanced Development Program

NASA Technical Reports Server (NTRS)

1990-01-01

This report contains the individual presentations delivered at the Space Station Evolution Symposium in League City, Texas on February 6, 7, 8, 1990. Personnel responsible for Advanced Systems Studies and Advanced Development within the Space Station Freedom program reported on the results of their work to date. Systems Studies presentations focused on identifying the baseline design provisions (hooks and scars) necessary to enable evolution of the facility to support changing space policy and anticipated user needs. Also emphasized were evolution configuration and operations concepts including on-orbit processing of space transfer vehicles. Advanced Development task managers discussed transitioning advanced technologies to the baseline program, including those near-term technologies which will enhance the safety and productivity of the crew and the reliability of station systems. Special emphasis was placed on applying advanced automation technology to ground and flight systems. This publication consists of two volumes. Volume 1 contains the results of the advanced system studies with the emphasis on reference evolution configurations, system design requirements and accommodations, and long-range technology projections. Volume 2 reports on advanced development tasks within the Transition Definition Program. Products of these tasks include: engineering fidelity demonstrations and evaluations on Station development testbeds and Shuttle-based flight experiments; detailed requirements and performance specifications which address advanced technology implementation issues; and mature applications and the tools required for the development, implementation, and support of advanced technology within the Space Station Freedom Program.

Can advanced technology improve future commuter aircraft

NASA Technical Reports Server (NTRS)

Williams, L. J.; Snow, D. B.

1981-01-01

The short-haul service abandoned by the trunk and local airlines is being picked up by the commuter airlines using small turboprop-powered aircraft. Most of the existing small transport aircraft currently available represent a relatively old technology level. However, several manufacturers have initiated the development of new or improved commuter transport aircraft. These aircraft are relatively conservative in terms of technology. An examination is conducted of advanced technology to identify those technologies that, if developed, would provide the largest improvements for future generations of these aircraft. Attention is given to commuter aircraft operating cost, aerodynamics, structures and materials, propulsion, aircraft systems, and technology integration. It is found that advanced technology can improve future commuter aircraft and that the largest of these improvements will come from the synergistic combination of technological advances in all of the aircraft disciplines. The most important goals are related to improved fuel efficiency and increased aircraft productivity.

Micro- and Nano-scale Technologies for Delivery into Adherent Cells

PubMed Central

Kang, Wonmo; McNaughton, Rebecca L.; Espinosa, Horacio D.

2016-01-01

Several recent micro- and nano-technologies have provided novel methods for biological studies of adherent cells because the small features of these new biotools provide unique capabilities for accessing cells without the need for suspension or lysis. These novel approaches have enabled gentle, yet effective delivery of molecules into specific adhered target cells, with unprecedented spatial resolution. Here we review recent progress in the development of these technologies with an emphasis on in vitro delivery into adherent cells utilizing mechanical penetration or electroporation. We discuss major advantages and limitations of these approaches and propose possible strategies for improvements. Finally, we discuss the impact of these technologies on biological research concerning cell-specific temporal studies, e.g., non-destructive sampling and analysis of intracellular molecules. Need For Techniques To Study Adherent Cells A mechanistic understanding of cell biology is often limited by both the complexity of the processes and limitations of commonly available research tools that lack temporal or spatial resolution. The lack of tools capable of providing cell-specific, non-destructive biomolecular delivery and analysis is a particular barrier for advancing fundamental discoveries of cell heterogeneity, single-cell behavior within a complex environment, and the mechanisms that govern disease states, responses to drugs or other stimuli, and differentiation of stem cells. To gain new mechanistic understanding, advances in methods for precise intracellular delivery and non-destructive biochemical analyses of non-secretory molecules (e.g., mRNA and proteins) are greatly needed so that individual cells can be experimentally controlled and repeatedly analyzed over time and/or within a particular location of the cell. For example, developing neurons must undergo a series of sequential changes in gene expression to achieve a mature phenotype; hence, understanding the process will require the ability to accurately monitor the sequence of intracellular events, within individual cells, in a non-destructive manner. In addition, neuronal maturation is influenced by interactions with surrounding cells and with extracellular matrix, so it is necessary to be able to simultaneously monitor events occurring in multiple cells that are interacting with each other and with the matrix. While the requirements are challenging, these experimental capabilities would provide unprecedented insight into the determinants of both the timing of cellular processes and their phenotype, the principles of cell heterogeneity, and the role of cell-cell communication in homogeneous cell populations and co-cultures. Because most cells adhere to a substrate or to other cells during their growth or differentiation [1], it is advantageous for new technologies to be capable of accessing adhered cells to avoid the need to disrupt cell processes by suspension and replating. Several technologies for studying adhered cells are currently being developed, and due to the need for individual cell access and non-destructive probing, micro- and nano-technologies are a natural choice because they interact with cells at the appropriate length scale, reduce the working volume of expensive reagents, require less time and space for replicates, allow for automation and integration of sequential analyses, enable portability, and reduce waste [2, 3]. Here we present an overview of recently developed micro- and nano-tools, with a focus on trends in intracellular delivery for in vitro studies of adhered cells, and highlight major advantages/disadvantages of these technologies with respect to features such as individual cell selectivity, spatial resolution, non-destructive cell analysis, and potential for high throughput or automation. Finally, we discuss the exciting promise for these technologies to cause a paradigm shift in biological research by providing methods to study cells over time at the individual cell level. PMID:27287927

Technology sensitivity studies for a Mach 3.0 civil transport

NASA Technical Reports Server (NTRS)

Coen, Peter G.

1988-01-01

The level of technological sophistication required for the economic viability and environmental acceptability of a Mach 3.0-cruise SST is evaluated, with a view to the development schedule and initial operating date into which the maturity of various essential technologies will translate. Attention is given to the effect of advanced aerodynamic, propulsion, structural and subsystem technologies on takeoff gross weight. A dramatic impact is noted to result from the combination of prospective technological advances in flow laminarization, advanced structures and materials, etc.