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Sample records for advanced storage manager

  1. Advanced Energy Storage Management in Distribution Network

    SciTech Connect

    Liu, Guodong; Ceylan, Oguzhan; Xiao, Bailu; Starke, Michael R; Ollis, T Ben; King, Daniel J; Irminger, Philip; Tomsovic, Kevin

    2016-01-01

    With increasing penetration of distributed generation (DG) in the distribution networks (DN), the secure and optimal operation of DN has become an important concern. In this paper, an iterative mixed integer quadratic constrained quadratic programming model to optimize the operation of a three phase unbalanced distribution system with high penetration of Photovoltaic (PV) panels, DG and energy storage (ES) is developed. The proposed model minimizes not only the operating cost, including fuel cost and purchasing cost, but also voltage deviations and power loss. The optimization model is based on the linearized sensitivity coefficients between state variables (e.g., node voltages) and control variables (e.g., real and reactive power injections of DG and ES). To avoid slow convergence when close to the optimum, a golden search method is introduced to control the step size and accelerate the convergence. The proposed algorithm is demonstrated on modified IEEE 13 nodes test feeders with multiple PV panels, DG and ES. Numerical simulation results validate the proposed algorithm. Various scenarios of system configuration are studied and some critical findings are concluded.

  2. Advanced materials for energy storage.

    PubMed

    Liu, Chang; Li, Feng; Ma, Lai-Peng; Cheng, Hui-Ming

    2010-02-23

    Popularization of portable electronics and electric vehicles worldwide stimulates the development of energy storage devices, such as batteries and supercapacitors, toward higher power density and energy density, which significantly depends upon the advancement of new materials used in these devices. Moreover, energy storage materials play a key role in efficient, clean, and versatile use of energy, and are crucial for the exploitation of renewable energy. Therefore, energy storage materials cover a wide range of materials and have been receiving intensive attention from research and development to industrialization. In this Review, firstly a general introduction is given to several typical energy storage systems, including thermal, mechanical, electromagnetic, hydrogen, and electrochemical energy storage. Then the current status of high-performance hydrogen storage materials for on-board applications and electrochemical energy storage materials for lithium-ion batteries and supercapacitors is introduced in detail. The strategies for developing these advanced energy storage materials, including nanostructuring, nano-/microcombination, hybridization, pore-structure control, configuration design, surface modification, and composition optimization, are discussed. Finally, the future trends and prospects in the development of advanced energy storage materials are highlighted. PMID:20217798

  3. Storage resource manager

    SciTech Connect

    Perelmutov, T.; Bakken, J.; Petravick, D.; /Fermilab

    2004-12-01

    Storage Resource Managers (SRMs) are middleware components whose function is to provide dynamic space allocation and file management on shared storage components on the Grid[1,2]. SRMs support protocol negotiation and reliable replication mechanism. The SRM standard supports independent SRM implementations, allowing for a uniform access to heterogeneous storage elements. SRMs allow site-specific policies at each location. Resource Reservations made through SRMs have limited lifetimes and allow for automatic collection of unused resources thus preventing clogging of storage systems with ''orphan'' files. At Fermilab, data handling systems use the SRM management interface to the dCache Distributed Disk Cache [5,6] and the Enstore Tape Storage System [15] as key components to satisfy current and future user requests [4]. The SAM project offers the SRM interface for its internal caches as well.

  4. Trends in Global Demonstrations of Carbon Management Technologies to Advance Coal- Based Power Generation With Carbon Capture and Storage

    NASA Astrophysics Data System (ADS)

    Cohen, K. K.; Plasynski, S.; Feeley, T. J.

    2008-05-01

    conditions with geophysics. Borehole-based technologies include a novel geochemical two-phase reservoir sampler deployed at Otway, and thermal-based measurements at CO2SINK for coupled hydrologic-geochemical reservoir analyses. Seismic, geomechanical, hydrologic, geochemical, and core studies are used in a multidisciplinary approach to assess CO2 trapping and reservoir integrity at In Salah. With estimated lifetime storage of 17 MtCO2 at In Salah, this and other CCS demonstrations provide opportunities to gain commercial experience for advancing coal-based power generation-CCS for carbon management.

  5. Berkeley Storage Manager

    2007-03-01

    Storage Resource Managers (SRMs) are middleware components whose function is to provide dynamic space allocation and file management of shared storage components on the Grid, They provide storage availability for the planning and execution of a Grid job. SRMs manage two types of resources: space and files. When managing space, SRMs negotiate space allocation with the requesting client, andlor assign default space quotas. When managing files, SRMs allocate space for files, invoke file transfer servicesmore » to move files into the space. phi files for a certain lifetime, release files upon the clients’ request, and use file replacement policies to optimize the use of the shared space. SPMs can be designed to provide effective sharing of files, by monitoring the activity of shared files, and make dynamic decisions on which files to replace when space is needed. In addition, SRMs perform automatic gathage collection of unused files by removing selected files whose lifetime has expired when space is needed. BeStMan is a Java implementation of SRM functionality by the Scientific Data Management Group at LBNL. It manages multiple disks as well as the HPSS mass storage system, and can be adapted to other storage systems. The BeStMan package contains the SRM server, the SRM client tools, and SRM testing tools.« less

  6. Berkeley Storage Manager

    SciTech Connect

    Sim, Alex; Gu, Junmin; Natarajan, Vijaya; Shoshani, Arie

    2007-03-01

    Storage Resource Managers (SRMs) are middleware components whose function is to provide dynamic space allocation and file management of shared storage components on the Grid, They provide storage availability for the planning and execution of a Grid job. SRMs manage two types of resources: space and files. When managing space, SRMs negotiate space allocation with the requesting client, andlor assign default space quotas. When managing files, SRMs allocate space for files, invoke file transfer services to move files into the space. phi files for a certain lifetime, release files upon the clients’ request, and use file replacement policies to optimize the use of the shared space. SPMs can be designed to provide effective sharing of files, by monitoring the activity of shared files, and make dynamic decisions on which files to replace when space is needed. In addition, SRMs perform automatic gathage collection of unused files by removing selected files whose lifetime has expired when space is needed. BeStMan is a Java implementation of SRM functionality by the Scientific Data Management Group at LBNL. It manages multiple disks as well as the HPSS mass storage system, and can be adapted to other storage systems. The BeStMan package contains the SRM server, the SRM client tools, and SRM testing tools.

  7. Advanced long term cryogenic storage systems

    NASA Technical Reports Server (NTRS)

    Brown, Norman S.

    1987-01-01

    Long term, cryogenic fluid storage facilities will be required to support future space programs such as the space-based Orbital Transfer Vehicle (OTV), Telescopes, and Laser Systems. An orbital liquid oxygen/liquid hydrogen storage system with an initial capacity of approximately 200,000 lb will be required. The storage facility tank design must have the capability of fluid acquisition in microgravity and limit cryogen boiloff due to environmental heating. Cryogenic boiloff management features, minimizing Earth-to-orbit transportation costs, will include advanced thick multilayer insulation/integrated vapor cooled shield concepts, low conductance support structures, and refrigeration/reliquefaction systems. Contracted study efforts are under way to develop storage system designs, technology plans, test article hardware designs, and develop plans for ground/flight testing.

  8. Energy Storage (II): Developing Advanced Technologies

    ERIC Educational Resources Information Center

    Robinson, Arthur L

    1974-01-01

    Energy storage, considered by some scientists to be the best technological and economic advancement after advanced nuclear power, still rates only modest funding for research concerning the development of advanced technologies. (PEB)

  9. Advanced optical disk storage technology

    NASA Technical Reports Server (NTRS)

    Haritatos, Fred N.

    1996-01-01

    There is a growing need within the Air Force for more and better data storage solutions. Rome Laboratory, the Air Force's Center of Excellence for C3I technology, has sponsored the development of a number of operational prototypes to deal with this growing problem. This paper will briefly summarize the various prototype developments with examples of full mil-spec and best commercial practice. These prototypes have successfully operated under severe space, airborne and tactical field environments. From a technical perspective these prototypes have included rewritable optical media ranging from a 5.25-inch diameter format up to the 14-inch diameter disk format. Implementations include an airborne sensor recorder, a deployable optical jukebox and a parallel array of optical disk drives. They include stand-alone peripheral devices to centralized, hierarchical storage management systems for distributed data processing applications.

  10. Automated Store Management For Drum Storage Facility

    SciTech Connect

    Koller, W.; Lang, R.

    2008-07-01

    This paper describes advanced system technology developed for a new Drum Storage Facility to be operated by Taiwan Power Company (TPC). A logistics management concept is applied for the storage of solid rad-wastes in terms of automated handling, transportation and storing as well as in terms of data management. The individual equipments, such as automated Bridge Cranes, Automatic Guided Vehicles and auxiliary systems are introduced in this paper and the store management process is outlined. The authors report furthermore on challenges during the design and engineering phase and review the project implementation from the equipment supplier's end. (authors)

  11. Methane storage in advanced porous materials.

    PubMed

    Makal, Trevor A; Li, Jian-Rong; Lu, Weigang; Zhou, Hong-Cai

    2012-12-01

    The need for alternative fuels is greater now than ever before. With considerable sources available and low pollution factor, methane is a natural choice as petroleum replacement in cars and other mobile applications. However, efficient storage methods are still lacking to implement the application of methane in the automotive industry. Advanced porous materials, metal-organic frameworks and porous organic polymers, have received considerable attention in sorptive storage applications owing to their exceptionally high surface areas and chemically-tunable structures. In this critical review we provide an overview of the current status of the application of these two types of advanced porous materials in the storage of methane. Examples of materials exhibiting high methane storage capacities are analyzed and methods for increasing the applicability of these advanced porous materials in methane storage technologies described. PMID:22990753

  12. Management of advanced melanoma

    SciTech Connect

    Nathanson, L. )

    1986-01-01

    This book presents papers on the subject of management of advanced melanoma. The topics covered are: non-investigational cytotoxic agents; high-dosage chemotherapy in antologous bone marrow transplantation; Radiotherapy of melanomas; hyperthermia; ureal melanoma; surgical treatment of recurrent a metastatic melanoma; role of interferons in management of melanoma and molecular genetics of melanoma.

  13. Advanced Distribution Management System

    NASA Astrophysics Data System (ADS)

    Avazov, Artur R.; Sobinova, Liubov A.

    2016-02-01

    This article describes the advisability of using advanced distribution management systems in the electricity distribution networks area and considers premises of implementing ADMS within the Smart Grid era. Also, it gives the big picture of ADMS and discusses the ADMS advantages and functionalities.

  14. Advances in macromolecular data storage

    NASA Astrophysics Data System (ADS)

    Mansuripur, Masud

    2014-09-01

    We propose to develop a new method of information storage to replace magnetic hard disk drives and other instruments of secondary/backup data storage. The proposed method stores petabytes of user-data in a sugar cube (1 cm3), and can read/write that information at hundreds of megabits/sec. Digital information is recorded and stored in the form of a long macromolecule consisting of at least two bases, 𝐴 and 𝐵. (This would be similar to DNA strands constructed from the four nucleic acids 𝐺, 𝐶, 𝐴, 𝑇.) The macromolecules initially enter the system as blank slates. A macromolecule with, say, 10,000 identical bases in the form of 𝐴𝐴𝐴𝐴𝐴. . . . 𝐴𝐴𝐴 may be used to record a kilobyte block of user-data (including modulation and error-correction coding), although, in this blank state, it can only represent the null sequence 00000....000. Suppose this blank string of 𝐴's is dragged before an atomically-sharp needle of a scanning tunneling microscope (STM). When electric pulses are applied to the needle in accordance with the sequence of 0s and 1s of a 1 𝑘𝐵 block of user-data, selected 𝐴 molecules will be transformed into 𝐵 molecules (e.g., a fraction of 𝐴 will be broken off and discarded). The resulting string now encodes the user-data in the form of 𝐴𝐴𝐵𝐴𝐵𝐵𝐴. . . 𝐵𝐴𝐵. The same STM needle can subsequently read the recorded information, as 𝐴 and 𝐵 would produce different electric signals when the strand passes under the needle. The macromolecule now represents a data block to be stored in a "parking lot" within the sugar cube, and later brought to a read station on demand. Millions of parking spots and thousands of Read/Write stations may be integrated within the micro-fabricated sugar cube, thus providing access to petabytes of

  15. Hierarchical storage management system evaluation

    NASA Technical Reports Server (NTRS)

    Woodrow, Thomas S.

    1993-01-01

    The Numerical Aerodynamic Simulation (NAS) Program at NASA Ames Research Center has been developing a hierarchical storage management system, NAStore, for some 6 years. This evaluation compares functionality, performance, reliability, and other factors of NAStore and three commercial alternatives. FileServ is found to be slightly better overall than NAStore and DMF. UniTree is found to be severely lacking in comparison.

  16. ADVANCED UNDERGROUND GAS STORAGE CONCEPTS REFRIGERATED-MINED CAVERN STORAGE

    SciTech Connect

    1998-09-01

    Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill-withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. Five regions of the U.S.A. were studied for underground storage development and PB-KBB reviewed the literature to determine if the geology of these regions was suitable for siting hard rock storage caverns. Area gas market conditions in these regions were also studied to determine the need for such storage. Based on an analysis of many factors, a possible site was determined to be in Howard and Montgomery Counties, Maryland. The area has compatible geology and a gas industry infrastructure for the nearby market populous of Baltimore and Washington D.C.. As Gas temperature is lowered, the compressibility of the gas reaches an optimum value. The compressibility of the gas, and the resultant gas density, is a function of temperature and pressure. This relationship can be used to commercial advantage by reducing the size of a storage cavern for a given working volume of natural gas. This study looks at this relationship and and the potential for commercialization of the process in a storage application. A conceptual process design, and cavern design were developed for various operating conditions. Potential site locations were considered

  17. Flywheel energy storage advances using HTS bearings.

    SciTech Connect

    Mulcahy, T. M.

    1998-09-11

    High-Temperature-Superconducting (HT) bearings have the potential to reduce idling losses and make flywheel energy storage economical. Demonstration of large, high-speed flywheels is key to market penetration. Toward this goal, a flywheel system has been developed and tested with 5-kg to 15-kg disk-shaped rotors. Rlm speeds exceeded 400 mls and stored energies were >80 W-hr. Test implementation required technological advances in nearly all aspects of the flywheel system. Features and limitations of the design and tests are discussed, especially those related to achieving additional energy storage.

  18. Underground storage tank management plan

    SciTech Connect

    1994-09-01

    The Underground Storage Tank (UST) Management Program at the Oak Ridge Y-12 Plant was established to locate UST systems in operation at the facility, to ensure that all operating UST systems are free of leaks, and to establish a program for the removal of unnecessary UST systems and upgrade of UST systems that continue to be needed. The program implements an integrated approach to the management of UST systems, with each system evaluated against the same requirements and regulations. A common approach is employed, in accordance with Tennessee Department of Environment and Conservation (TDEC) regulations and guidance, when corrective action is mandated. This Management Plan outlines the compliance issues that must be addressed by the UST Management Program, reviews the current UST inventory and compliance approach, and presents the status and planned activities associated with each UST system. The UST Management Plan provides guidance for implementing TDEC regulations and guidelines for petroleum UST systems. (There are no underground radioactive waste UST systems located at Y-12.) The plan is divided into four major sections: (1) regulatory requirements, (2) implementation requirements, (3) Y-12 Plant UST Program inventory sites, and (4) UST waste management practices. These sections describe in detail the applicable regulatory drivers, the UST sites addressed under the Management Program, and the procedures and guidance used for compliance with applicable regulations.

  19. Solar thermoelectricity via advanced latent heat storage

    NASA Astrophysics Data System (ADS)

    Olsen, M. L.; Rea, J.; Glatzmaier, G. C.; Hardin, C.; Oshman, C.; Vaughn, J.; Roark, T.; Raade, J. W.; Bradshaw, R. W.; Sharp, J.; Avery, A. D.; Bobela, D.; Bonner, R.; Weigand, R.; Campo, D.; Parilla, P. A.; Siegel, N. P.; Toberer, E. S.; Ginley, D. S.

    2016-05-01

    We report on a new modular, dispatchable, and cost-effective solar electricity-generating technology. Solar ThermoElectricity via Advanced Latent heat Storage (STEALS) integrates several state-of-the-art technologies to provide electricity on demand. In the envisioned STEALS system, concentrated sunlight is converted to heat at a solar absorber. The heat is then delivered to either a thermoelectric (TE) module for direct electricity generation, or to charge a phase change material for thermal energy storage, enabling subsequent generation during off-sun hours, or both for simultaneous electricity production and energy storage. The key to making STEALS a dispatchable technology lies in the development of a "thermal valve," which controls when heat is allowed to flow through the TE module, thus controlling when electricity is generated. The current project addresses each of the three major subcomponents, (i) the TE module, (ii) the thermal energy storage system, and (iii) the thermal valve. The project also includes system-level and techno- economic modeling of the envisioned integrated system and will culminate in the demonstration of a laboratory-scale STEALS prototype capable of generating 3kWe.

  20. NREL Advances Spillover Materials for Hydrogen Storage (Fact Sheet)

    SciTech Connect

    Not Available

    2010-12-01

    This fact sheet describes NREL's accomplishments in advancing spillover materials for hydrogen storage and improving the reproducible synthesis, long-term durability, and material costs of hydrogen storage materials. Work was performed by NREL's Chemical and Materials Science Center.

  1. Management issues for high performance storage systems

    SciTech Connect

    Louis, S.; Burris, R.

    1995-03-01

    Managing distributed high-performance storage systems is complex and, although sharing common ground with traditional network and systems management, presents unique storage-related issues. Integration technologies and frameworks exist to help manage distributed network and system environments. Industry-driven consortia provide open forums where vendors and users cooperate to leverage solutions. But these new approaches to open management fall short addressing the needs of scalable, distributed storage. We discuss the motivation and requirements for storage system management (SSM) capabilities and describe how SSM manages distributed servers and storage resource objects in the High Performance Storage System (HPSS), a new storage facility for data-intensive applications and large-scale computing. Modem storage systems, such as HPSS, require many SSM capabilities, including server and resource configuration control, performance monitoring, quality of service, flexible policies, file migration, file repacking, accounting, and quotas. We present results of initial HPSS SSM development including design decisions and implementation trade-offs. We conclude with plans for follow-on work and provide storage-related recommendations for vendors and standards groups seeking enterprise-wide management solutions.

  2. Advanced energy storage for space applications: A follow-up

    NASA Technical Reports Server (NTRS)

    Halpert, Gerald; Surampudi, Subbarao

    1994-01-01

    Viewgraphs on advanced energy storage for space applications are presented. Topics covered include: categories of space missions using batteries; battery challenges; properties of SOA and advanced primary batteries; lithium primary cell applications; advanced rechargeable battery applications; present limitations of advanced battery technologies; and status of Li-TiS2, Ni-MH, and Na-NiCl2 cell technologies.

  3. Optimization-based power management of hybrid power systems with applications in advanced hybrid electric vehicles and wind farms with battery storage

    NASA Astrophysics Data System (ADS)

    Borhan, Hoseinali

    Modern hybrid electric vehicles and many stationary renewable power generation systems combine multiple power generating and energy storage devices to achieve an overall system-level efficiency and flexibility which is higher than their individual components. The power or energy management control, "brain" of these "hybrid" systems, determines adaptively and based on the power demand the power split between multiple subsystems and plays a critical role in overall system-level efficiency. This dissertation proposes that a receding horizon optimal control (aka Model Predictive Control) approach can be a natural and systematic framework for formulating this type of power management controls. More importantly the dissertation develops new results based on the classical theory of optimal control that allow solving the resulting optimal control problem in real-time, in spite of the complexities that arise due to several system nonlinearities and constraints. The dissertation focus is on two classes of hybrid systems: hybrid electric vehicles in the first part and wind farms with battery storage in the second part. The first part of the dissertation proposes and fully develops a real-time optimization-based power management strategy for hybrid electric vehicles. Current industry practice uses rule-based control techniques with "else-then-if" logic and look-up maps and tables in the power management of production hybrid vehicles. These algorithms are not guaranteed to result in the best possible fuel economy and there exists a gap between their performance and a minimum possible fuel economy benchmark. Furthermore, considerable time and effort are spent calibrating the control system in the vehicle development phase, and there is little flexibility in real-time handling of constraints and re-optimization of the system operation in the event of changing operating conditions and varying parameters. In addition, a proliferation of different powertrain configurations may

  4. Emerging Network Storage Management Standards for Intelligent Data Storage Subsystems

    NASA Technical Reports Server (NTRS)

    Podio, Fernando; Vollrath, William; Williams, Joel; Kobler, Ben; Crouse, Don

    1998-01-01

    This paper discusses the need for intelligent storage devices and subsystems that can provide data integrity metadata, the content of the existing data integrity standard for optical disks and techniques and metadata to verify stored data on optical tapes developed by the Association for Information and Image Management (AIIM) Optical Tape Committee.

  5. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false May an advance of funds be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105 Public... transporting HHG and temporary storage? An advance of funds may be authorized when the transportation of...

  6. Management of advanced corneal ectasias.

    PubMed

    Maharana, Prafulla K; Dubey, Aditi; Jhanji, Vishal; Sharma, Namrata; Das, Sujata; Vajpayee, Rasik B

    2016-01-01

    Corneal ectasias include a group of disorders characterised by progressive thinning, bulging and distortion of the cornea. Keratoconus is the most common disease in this group. Other manifestations include pellucid marginal degeneration, Terrien's marginal degeneration, keratoglobus and ectasias following surgery. Advanced ectasias usually present with loss of vision due to high irregular astigmatism. Management of these disorders is difficult due to the peripheral location of ectasia and associated severe corneal thinning. Newer contact lenses such as scleral lenses are helpful in a selected group of patients. A majority of these cases requires surgical intervention. This review provides an update on the current treatment modalities available for management of advanced corneal ectasias. PMID:26294106

  7. Advances in Energy Management Systems

    SciTech Connect

    Horton, J.S.; Prince, B.; Sasson, A.M.; Wynne, W.T.; Trefny, F.; Cleveland, F.

    1986-08-01

    This paper is one of the series prepared for a special session to be held at PICA 85. The objective is to review the advances that have been made in Energy Management Systems and to obtain a more common agreement as to the usefulness and future of such systems. The paper contains a summary of five discussions of Energy Management Systems. These discussions focus on the major components of an Energy Management System and address important questions as to the usefulness, past developments, the current state-of-the-art, and needs in Energy Management Systems. Each author provides a different perspective of these systems. The discussions are intended to provide insight into Energy Management Systems, to solicit discussions, and to provide a forum for discussions of Energy Management System's developments and future needs.

  8. Thermal Storage and Advanced Heat Transfer Fluids (Fact Sheet)

    SciTech Connect

    Not Available

    2010-08-01

    Fact sheet describing NREL CSP Program capabilities in the area of thermal storage and advanced heat transfer fluids: measuring thermophysical properties, measuring fluid flow and heat transfer, and simulating flow of thermal energy and fluid.

  9. Advanced potato breeding clones: storage and processing evaluation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The accumulation of reducing sugars during cold storage of potato tubers is a serious and costly problem for producers and processors. The degree to which cultivars accumulate reducing sugars during storage determines their processing and market potential. Cultivars or advanced breeding lines with...

  10. Measurement of storage ring motion at the advanced light source

    SciTech Connect

    Krebs, G.F.

    1997-05-01

    The mechanical stability of the Advanced Light Source storage ring is examined over a period of 1.5 years from the point of view of floor motion. The storage ring beam position monitor stability is examined under various operating conditions.

  11. Ada programming guidelines for deterministic storage management

    NASA Technical Reports Server (NTRS)

    Auty, David

    1988-01-01

    Previous reports have established that a program can be written in the Ada language such that the program's storage management requirements are determinable prior to its execution. Specific guidelines for ensuring such deterministic usage of Ada dynamic storage requirements are described. Because requirements may vary from one application to another, guidelines are presented in a most-restrictive to least-restrictive fashion to allow the reader to match appropriate restrictions to the particular application area under investigation.

  12. Advanced Gas Storage Concepts: Technologies for the Future

    SciTech Connect

    Freeway, Katy; Rogers, R.E.; DeVries, Kerry L.; Nieland, Joel D.; Ratigan, Joe L.; Mellegard, Kirby D.

    2000-02-01

    This full text product includes: 1) A final technical report titled Advanced Underground Gas Storage Concepts, Refrigerated-Mined Cavern Storage and presentations from two technology transfer workshops held in 1998 in Houston, Texas, and Pittsburgh, Pennsylvania (both on the topic of Chilled Gas Storage in Mined Caverns); 2) A final technical report titled Natural Gas Hydrates Storage Project, Final Report 1 October 1997 - 31 May 1999; 3) A final technical report titled Natural Gas Hydrates Storage Project Phase II: Conceptual Design and Economic Study, Final Report 9 June - 10 October 1999; 4) A final technical report titled Commerical Potential of Natural Gas Storage in Lined Rock Caverns (LRC) and presentations from a DOE-sponsored workshop on Alternative Gas Storage Technologies, held Feb 17, 2000 in Pittsburgh, PA; and 5) Phase I and Phase II topical reports titled Feasibility Study for Lowering the Minimum Gas Pressure in Solution-Mined Caverns Based on Geomechanical Analyses of Creep-Induced Damage and Healing.

  13. Thermal energy storage chiller management

    SciTech Connect

    Williams, C.D.

    1996-11-01

    This paper addresses chiller applications that are designed to get the maximum benefit form a chiller plant every day of the year. It treats all chillers as variable-capacity devices and applies them in thermal storage system configurations that efficiently take advantage of that capability. It also recognizes that a chiller operating temperature differential is always a variable to which a chiller must always adjust. All the applications addressed vary the flow and in some situations the operating temperature differential to maximize or optimize each chiller`s capacity. It is done in such a manner that the safety and reliability of the chiller are improved rather than jeopardized.

  14. USB Mass Storage Device Manager

    SciTech Connect

    Rymer, Bernard; Cowart, Casey

    2004-06-17

    The USB probram is designed to give some level of control over the use of USB mass storage devices (MSDs). This program allows you to disable all USB MSDs from working on a machine or to configure specific devices for the machine as an administrator. For complete control over USB MSDs the user of the machine must belong to the 'User' group. If a MSD has already been configured on the machine it will continue to function after using the 'Activate Administrator Control' function. The only way to disable previously configured devices is to use the 'Block' feature to block all MSDs from being used on the machine.

  15. Advanced Liquid Natural Gas Onboard Storage System

    SciTech Connect

    Greg Harper; Charles Powars

    2003-10-31

    Cummins Westport Incorporated (CWI) has designed and developed a liquefied natural gas (LNG) vehicle fuel system that includes a reciprocating pump with the cold end submerged in LNG contained in a vacuum-jacketed tank. This system was tested and analyzed under the U.S. Department of Energy (DOE) Advanced LNG Onboard Storage System (ALOSS) program. The pumped LNG fuel system developed by CWI and tested under the ALOSS program is a high-pressure system designed for application on Class 8 trucks powered by CWI's ISX G engine, which employs high-pressure direct injection (HPDI) technology. A general ALOSS program objective was to demonstrate the feasibility and advantages of a pumped LNG fuel system relative to on-vehicle fuel systems that require the LNG to be ''conditioned'' to saturation pressures that exceeds the engine fuel pressure requirements. These advantages include the capability to store more fuel mass in given-size vehicle and station tanks, and simpler lower-cost LNG refueling stations that do not require conditioning equipment. Pumped LNG vehicle fuel systems are an alternative to conditioned LNG systems for spark-ignition natural gas and port-injection dual-fuel engines (which typically require about 100 psi), and they are required for HPDI engines (which require over 3,000 psi). The ALOSS program demonstrated the feasibility of a pumped LNG vehicle fuel system and the advantages of this design relative to systems that require conditioning the LNG to a saturation pressure exceeding the engine fuel pressure requirement. LNG tanks mounted on test carts and the CWI engineering truck were repeatedly filled with LNG saturated at 20 to 30 psig. More fuel mass was stored in the vehicle tanks as well as the station tank, and no conditioning equipment was required at the fueling station. The ALOSS program also demonstrated the general viability and specific performance of the CWI pumped LNG fuel system design. The system tested as part of this program is

  16. Advanced Heat Transfer and Thermal Storage Fluids

    SciTech Connect

    Moens, L.; Blake, D.

    2005-01-01

    The design of the next generation solar parabolic trough systems for power production will require the development of new thermal energy storage options with improved economics or operational characteristics. Current heat-transfer fluids such as VP-1?, which consists of a eutectic mixture of biphenyl and diphenyl oxide, allow a maximum operating temperature of ca. 300 C, a limit above which the vapor pressure would become too high and would require pressure-rated tanks. The use of VP-1? also suffers from a freezing point around 13 C that requires heating during cold periods. One of the goals for future trough systems is the use of heat-transfer fluids that can act as thermal storage media and that allow operating temperatures around 425 C combined with lower limits around 0 C. This paper presents an outline of our latest approach toward the development of such thermal storage fluids.

  17. Advanced Energy Storage for Space Applications

    NASA Technical Reports Server (NTRS)

    Halpert, G.; Surampudi, S.

    1993-01-01

    NASA is planning a number of space science and space exploration missions into the early 21st century. The JPL Advanced Battery Program, which has the goal of developing batteries for these missions, is described. Under program consideration are Li-SOCl(sub 2) cells, secondary lithium cells, advanced metal hydride cells, and high-temperature sodium-nickel chloride cells.

  18. Advances in prehospital airway management

    PubMed Central

    Jacobs, PE; Grabinsky, A

    2014-01-01

    Prehospital airway management is a key component of emergency responders and remains an important task of Emergency Medical Service (EMS) systems worldwide. The most advanced airway management techniques involving placement of oropharyngeal airways such as the Laryngeal Mask Airway or endotracheal tube. Endotracheal tube placement success is a common measure of out-of-hospital airway management quality. Regional variation in regard to training, education, and procedural exposure may be the major contributor to the findings in success and patient outcome. In studies demonstrating poor outcomes related to prehospital-attempted endotracheal intubation (ETI), both training and skill level of the provider are usually often low. Research supports a relationship between the number of intubation experiences and ETI success. National standards for certification of emergency medicine provider are in general too low to guarantee good success rate in emergency airway management by paramedics and physicians. Some paramedic training programs require more intense airway training above the national standard and some EMS systems in Europe staff their system with anesthesia providers instead. ETI remains the cornerstone of definitive prehospital airway management, However, ETI is not without risk and outcomes data remains controversial. Many systems may benefit from more input and guidance by the anesthesia department, which have higher volumes of airway management procedures and extensive training and experience not just with training of airway management but also with different airway management techniques and adjuncts. PMID:24741499

  19. Water Management Applications of Advanced Precipitation Products

    NASA Astrophysics Data System (ADS)

    Johnson, L. E.; Braswell, G.; Delaney, C.

    2012-12-01

    Advanced precipitation sensors and numerical models track storms as they occur and forecast the likelihood of heavy rain for time frames ranging from 1 to 8 hours, 1 day, and extended outlooks out to 3 to 7 days. Forecast skill decreases at the extended time frames but the outlooks have been shown to provide "situational awareness" which aids in preparation for flood mitigation and water supply operations. In California the California-Nevada River Forecast Centers and local Weather Forecast Offices provide precipitation products that are widely used to support water management and flood response activities of various kinds. The Hydrometeorology Testbed (HMT) program is being conducted to help advance the science of precipitation tracking and forecasting in support of the NWS. HMT high-resolution products have found applications for other non-federal water management activities as well. This presentation will describe water management applications of HMT advanced precipitation products, and characterization of benefits expected to accrue. Two case examples will be highlighted, 1) reservoir operations for flood control and water supply, and 2) urban stormwater management. Application of advanced precipitation products in support of reservoir operations is a focus of the Sonoma County Water Agency. Examples include: a) interfacing the high-resolution QPE products with a distributed hydrologic model for the Russian-Napa watersheds, b) providing early warning of in-coming storms for flood preparedness and water supply storage operations. For the stormwater case, San Francisco wastewater engineers are developing a plan to deploy high resolution gap-filling radars looking off shore to obtain longer lead times on approaching storms. A 4 to 8 hour lead time would provide opportunity to optimize stormwater capture and treatment operations, and minimize combined sewer overflows into the Bay.ussian River distributed hydrologic model.

  20. Advanced concepts in ground thermal energy storage systems

    NASA Astrophysics Data System (ADS)

    Woods, Kevin David

    In recent years, ground thermal energy storage has become a topic of interest in the energy community for solar thermal energy storage systems, ground sourced heat pump systems, and data center thermal management systems due to an increase in the energy efficiency of such systems utilizing the ground as a thermal reservoir. The most common method for transferring thermal energy to the ground formation is the geothermal borehole. This dissertation presents the state of the art in geothermal borehole modeling and derives novel analytical functions to model advanced concepts concerning their operation. The novel solutions derived allow a geothermal borehole designer to better understand and design ground energy storage systems. The state of the art in geothermal borehole modeling is the stationary line source solution which is limited to boreholes operating without groundwater flow. Novel solutions for modeling a geothermal borehole with groundwater advection are presented through derivation of a transient moving line source solution as well as a transient moving cylindrical surface source solution. These solutions are applied to model a specific type of open loop geothermal borehole called a standing column well with groundwater advection and are compared to empirical and numerical data for validation. The dissertation then moves into derivation of a property determination method for geothermal boreholes with groundwater advection. The traditional property determination method used to obtain ground formation properties is based on the stationary transient line source method and fails in the presence of groundwater flow. The proposed novel property determination method calculates the thermal conductivity, thermal diffusivity, and superficial flow velocity of groundwater within a ground formation. These methods and solutions are novel tools allowing for geothermal borehole designers to grasp a better understanding of the systems they are designing as well as open other

  1. USB Mass Storage Device Manager

    2004-06-17

    The USB probram is designed to give some level of control over the use of USB mass storage devices (MSDs). This program allows you to disable all USB MSDs from working on a machine or to configure specific devices for the machine as an administrator. For complete control over USB MSDs the user of the machine must belong to the 'User' group. If a MSD has already been configured on the machine it will continuemore » to function after using the 'Activate Administrator Control' function. The only way to disable previously configured devices is to use the 'Block' feature to block all MSDs from being used on the machine.« less

  2. Optical storage: Financial management and budget applications

    SciTech Connect

    Morris, J.D.; Emrich, M.L.

    1988-10-01

    Recent optical storage technology advances have improved the micro-computer's ability to handle large quantities of data. This paper will explain the evolution of this technology including the state of the art. The factors involved in this evolution will be described, namely the division of research into three distinct areas: Compact Disk Read Only Memory (CD-ROM); Write Once Read Many (WORM); and Erasable Optical Storage (EOS). The future implications of these areas will be reported. In addition, practical applications that utilize optical media in the financial environment will be highlighted. 3 figs., 1 tab., 10 refs.

  3. Storage resource managers: Middleware components for gridstorage

    SciTech Connect

    Shoshani, Arie; Sim, Alex; Gu, Junmin

    2005-08-18

    The amount of scientific data generated by simulations orcollected from large scale experiments have reached levels that cannot bestored in the researcher's workstation or even in his/her local computercenter. Such data are vital to large scientific collaborations dispersedover wide-area networks. In the past, the concept of a Gridinfrastructure [1]mainly emphasized the computational aspect ofsupporting large distributed computational tasks, and optimizing the useof the network by using bandwidth reservation techniques. In this paperwe discuss the concept of Storage Resource Managers (SRMs) as componentsthat complement this with the support for the storage management of largedistributed datasets. The access to data is becoming the main bottleneckin such "data intensive" applications because the data cannot bereplicated in all sites. SRMs can be used to dynamically optimize the useof storage resource to help unclog this bottleneck.

  4. Power Management for Space Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Jones, Harry

    2001-01-01

    Space power systems include the power source, storage, and management subsystems. In current crewed spacecraft, solar cells are the power source, batteries provide storage, and the crew performs any required load scheduling. For future crewed planetary surface systems using Advanced Life Support, we assume that plants will be grown to produce much of the crew's food and that nuclear power will be employed. Battery storage is much more costly than nuclear power capacity and so is not likely to be used. We investigate the scheduling of power demands by the crew or automatic control, to reduce the peak power load and the required generating capacity. The peak to average power ratio is a good measure of power use efficiency. We can easily schedule power demands to reduce the peak power from its maximum, but simple scheduling approaches may not find the lowest possible peak to average power ratio. An initial power scheduling example was simple enough for a human to solve, but a more complex example with many intermittent load demands required automatic scheduling. Excess power is a free resource and can be used even for minor benefits.

  5. Managing advanced unilateral pseudoexfoliative glaucoma.

    PubMed

    Marques, André

    2014-01-01

    The only proven therapy for glaucoma is intraocular pressure (IOP) reduction, which can be accomplished by different means. Each should be properly discussed with patients in order to best preserve visual function and quality of life. We report a case of unilateral pseudoexfoliative glaucoma, treated for years with triple topical IOP-lowering drugs. The patient presented with advanced optic neuropathy and important ocular side effects secondary to the treatment. Having discussed his options and prognosis, laser trabeculoplasty was performed while maintaining the remaining therapy considering the advanced stage of glaucoma. His IOP was effectively reduced and no progression was noted after 1-year follow-up. Although medical therapy is the mainstream in glaucoma management, its side effects should not be ignored, especially in unilateral cases. Surgery might have been a better solution, but we chose to perform laser trabeculoplasty, an effective and safer alternative, considering the unlikely but serious risk of the "wipe-out phenomenon" in this case. PMID:24850557

  6. A Framework for Managing Inter-Site Storage Area Networks using Grid Technologies

    NASA Technical Reports Server (NTRS)

    Kobler, Ben; McCall, Fritz; Smorul, Mike

    2006-01-01

    The NASA Goddard Space Flight Center and the University of Maryland Institute for Advanced Computer Studies are studying mechanisms for installing and managing Storage Area Networks (SANs) that span multiple independent collaborating institutions using Storage Area Network Routers (SAN Routers). We present a framework for managing inter-site distributed SANs that uses Grid Technologies to balance the competing needs to control local resources, share information, delegate administrative access, and manage the complex trust relationships between the participating sites.

  7. ATF (Advanced Toroidal Facility) data management

    SciTech Connect

    Kannan, K.L.; Baylor, L.R.

    1988-01-01

    Data management for the Advanced Toroidal Facility (ATF), a stellarator located at Oak Ridge National Laboratory (ORNL), is provided by DMG, a locally developed, VAX-based software system. DMG is a data storage and retrieval software system that provides the user interface to ATF raw and analyzed data. Data are described in terms of data models and data types and are organized as signals into files, which are internally documented. The system was designed with user accessibility, software maintainability, and extensibility as primary goals. Extensibility features include compatibility with ATF as it moves from pulsed to steady-state operation and capability for use of the DMG system with experiments other than ATF. DMG is implemented as a run-time library of routines available as a shareable image. General-purpose and specialized data acquisition and analysis applications have been developed using the DMG system. This paper describes the DMG system and the interfaces to it. 4 refs., 2 figs.

  8. Advanced Compact Holographic Data Storage System

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin; Zhou, Hanying; Reyes, George

    2000-01-01

    JPL, under current sponsorship from NASA Space Science and Earth Science Programs, is developing a high-density, nonvolatile and rad-hard Advanced Holographic Memory (AHM) system to enable large-capacity, high-speed, low power consumption, and read/write of data in a space environment. The entire read/write operation will be controlled with electro-optic mechanism without any moving parts. This CHDS will consist of laser diodes, photorefractive crystal, spatial light modulator, photodetector array, and I/O electronic interface. In operation, pages of information would be recorded and retrieved with random access and highspeed. The nonvolatile, rad-hard characteristics of the holographic memory will provide a revolutionary memory technology to enhance mission capabilities for all NASA's Earth Science Mission. In this paper, recent technology progress in developing this CHDS at JPL will be presented.

  9. Managing advanced unilateral pseudoexfoliative glaucoma

    PubMed Central

    Marques, André

    2014-01-01

    The only proven therapy for glaucoma is intraocular pressure (IOP) reduction, which can be accomplished by different means. Each should be properly discussed with patients in order to best preserve visual function and quality of life. We report a case of unilateral pseudoexfoliative glaucoma, treated for years with triple topical IOP-lowering drugs. The patient presented with advanced optic neuropathy and important ocular side effects secondary to the treatment. Having discussed his options and prognosis, laser trabeculoplasty was performed while maintaining the remaining therapy considering the advanced stage of glaucoma. His IOP was effectively reduced and no progression was noted after 1-year follow-up. Although medical therapy is the mainstream in glaucoma management, its side effects should not be ignored, especially in unilateral cases. Surgery might have been a better solution, but we chose to perform laser trabeculoplasty, an effective and safer alternative, considering the unlikely but serious risk of the “wipe-out phenomenon” in this case. PMID:24850557

  10. Advanced Underground Gas Storage Concepts: Refrigerated-Mined Cavern Storage, Final Report

    SciTech Connect

    1998-09-30

    Over the past 40 years, cavern storage of LPG's, petrochemicals, such as ethylene and propylene, and other petroleum products has increased dramatically. In 1991, the Gas Processors Association (GPA) lists the total U.S. underground storage capacity for LPG's and related products of approximately 519 million barrels (82.5 million cubic meters) in 1,122 separate caverns. Of this total, 70 are hard rock caverns and the remaining 1,052 are caverns in salt deposits. However, along the eastern seaboard of the U.S. and the Pacific northwest, salt deposits are not available and therefore, storage in hard rocks is required. Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. Competing methods include LNG facilities and remote underground storage combined with pipeline transportation to the area. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. DOE has identified five regions, that have not had favorable geological conditions for underground storage development: New England, Mid-Atlantic (NY/NJ), South Atlantic (DL/MD/VA), South Atlantic (NC/SC/GA), and the Pacific Northwest (WA/OR). PB-KBB reviewed published literature and in-house databases of the geology of these regions to determine suitability of hard rock formations for siting storage

  11. Advanced Thermal Energy Storage: Novel Tuning of Critical Fluctuations for Advanced Thermal Energy Storage

    SciTech Connect

    2011-12-01

    HEATS Project: NAVITASMAX is developing a novel thermal energy storage solution. This innovative technology is based on simple and complex supercritical fluids— substances where distinct liquid and gas phases do not exist, and tuning the properties of these fluid systems to increase their ability to store more heat. In solar thermal storage systems, heat can be stored in NAVITASMAX’s system during the day and released at night—when the sun is not shining—to drive a turbine and produce electricity. In nuclear storage systems, heat can be stored in NAVITASMAX’s system at night and released to produce electricity during daytime peak-demand hours.

  12. Storage Manager and File Transfer Web Services

    SciTech Connect

    William A Watson III; Ying Chen; Jie Chen; Walt Akers

    2002-07-01

    Web services are emerging as an interesting mechanism for a wide range of grid services, particularly those focused upon information services and control. When coupled with efficient data transfer services, they provide a powerful mechanism for building a flexible, open, extensible data grid for science applications. In this paper we present our prototype work on a Java Storage Resource Manager (JSRM) web service and a Java Reliable File Transfer (JRFT) web service. A java client (Grid File Manager) on top of JSRM and is developed to demonstrate the capabilities of these web services. The purpose of this work is to show the extent to which SOAP based web services are an appropriate direction for building a grid-wide data management system, and eventually grid-based portals.

  13. SSME Advanced Health Management: Project Overview

    NASA Technical Reports Server (NTRS)

    Plowden, John

    2000-01-01

    This document is the viewgraphs from a presentation concerning the development of the Health Management system for the Space Shuttle Main Engine (SSME). It reviews the historical background of the SSME Advanced Health Management effort through the present final Health management configuration. The document includes reviews of three subsystems to the Advanced Health Management System: (1) the Real-Time Vibration Monitor System, (2) the Linear Engine Model, and (3) the Optical Plume Anomaly Detection system.

  14. Technical basis for extending storage of the UK's advanced gas-cooled reactor fuel

    SciTech Connect

    Hambley, D.I.

    2013-07-01

    The UK Nuclear Decommissioning Agency has recently declared a date for cessation of reprocessing of oxide fuel from the UK's Advanced Gas-cooled Reactors (AGRs). This will fundamentally change the management of AGR fuel: from short term storage followed by reprocessing to long term fuel storage followed, in all likelihood, by geological disposal. In terms of infrastructure, the UK has an existing, modern wet storage asset that can be adapted for centralised long term storage of dismantled AGR fuel under the required pond water chemistry. No AGR dry stores exist, although small quantities of fuel have been stored dry as part of experimental programmes in the past. These experimental programmes have shown concerns about corrosion rates.

  15. Thermal management technology for hydrogen storage: Fullerene option

    SciTech Connect

    Wang, J.C.; Chen, F.C.; Murphy, R.W.

    1996-10-01

    Fullerenes are selected as the first option for investigating advanced thermal management technologies for hydrogen storage because of their potentially high volumetric and gravimetric densities. Experimental results indicate that about 6 wt% of hydrogen (corresponding to C{sub 60}H{sub 48}) can be added to and taken out of fullerenes. A model assuming thermally activated hydrogenation and dehydrogenation processes was developed to explain the experimental findings. The activation energies were estimated to be 100 and 160 kJ/mole (1.0 and 1.6 eV/H{sub 2}) for the hydrogenation and dehydrogenation processes, respectively. The difference is interpreted as the heat released during hydrogenation. There are indications that the activation energies and the heat of hydrogenation can be modified by the use of catalysts. Preliminary hydrogen storage simulations for a conceptually simple device were performed. A 1-m long hollow metal cylinder with an inner diameter of 0.02 m was assumed to be filled with fullerene powders. The results indicate that the thermal diffusivity of the fullerenes controls the hydrogenation and dehydrogenation rates. The rates can be significantly modified by changing the thermal diffusivity of the material inside the cylinder, e.g., by incorporating a metal mesh. Results from the simulation suggest that thermal management is essential for efficient hydrogen storage devices using fullerenes. While the preliminary models developed in this study explain some of the observation, more controlled experiments, rigorous model development, and physical property determinations are needed for the development of practical hydrogen storage devices. The use of catalysts to optimize the hydrogen storage characteristics of fullerenes also needs to be pursued. Future cooperative work between Oak Ridge National Laboratory (ORNL) and Material & Electrochemical Research Corporation (MER) is planned to address these needs.

  16. Thermal Storage Advanced Thruster System (TSATS) Experimental Program

    NASA Technical Reports Server (NTRS)

    Rose, M. Frank; Lisano, Michael E., II

    1991-01-01

    The Thermal Storage Advanced Thruster System (TSATS) rocket test stand is completely assembled and operational. The first trial experimental runs of a low-energy TSATS prototype rocket was made using the test stand. The features of the rocket test stand and the calibration of the associated diagnostics are described and discussed. Design and construction of the TSATS prototype are discussed, and experimental objectives, procedures, and results are detailed.

  17. Ganglioside storage diseases: on the road to management.

    PubMed

    Seyfried, Thomas N; Rockwell, Hannah E; Heinecke, Karie A; Martin, Douglas R; Sena-Esteves, Miguel

    2014-01-01

    Although the biochemical and genetic basis for the GM1 and GM2 gangliosidoses has been known for decades, effective therapies for these diseases remain in early stages of development. The difficulty with many therapeutic strategies for treating the gangliosidoses comes largely from their inability to remove stored ganglioside once it accumulates in central nervous system (CNS) neurons and glia. This chapter highlights advances made using substrate reduction therapy and gene therapy in reducing CNS ganglioside storage. Information obtained from mouse and feline models provides insight on therapeutic strategies that could be effective in human clinical trials. In addition, information is presented showing how a calorie-restricted diet might facilitate therapeutic drug delivery to the CNS. The development of multiple new therapeutic approaches offers hope that longer-term management of these diseases can be achieved. It is also clear that multiple therapeutic strategies will likely be needed to provide the most complete management. PMID:25151393

  18. Carbon nanomaterials for advanced energy conversion and storage.

    PubMed

    Dai, Liming; Chang, Dong Wook; Baek, Jong-Beom; Lu, Wen

    2012-04-23

    It is estimated that the world will need to double its energy supply by 2050. Nanotechnology has opened up new frontiers in materials science and engineering to meet this challenge by creating new materials, particularly carbon nanomaterials, for efficient energy conversion and storage. Comparing to conventional energy materials, carbon nanomaterials possess unique size-/surface-dependent (e.g., morphological, electrical, optical, and mechanical) properties useful for enhancing the energy-conversion and storage performances. During the past 25 years or so, therefore, considerable efforts have been made to utilize the unique properties of carbon nanomaterials, including fullerenes, carbon nanotubes, and graphene, as energy materials, and tremendous progress has been achieved in developing high-performance energy conversion (e.g., solar cells and fuel cells) and storage (e.g., supercapacitors and batteries) devices. This article reviews progress in the research and development of carbon nanomaterials during the past twenty years or so for advanced energy conversion and storage, along with some discussions on challenges and perspectives in this exciting field. PMID:22383334

  19. Efficient Management of Complex Striped Files in Active Storage

    SciTech Connect

    Piernas Canovas, Juan; Nieplocha, Jaroslaw

    2008-08-25

    Active Storage provides an opportunity for reducing the band- width requirements between the storage and compute elements of cur- rent supercomputing systems, and leveraging the processing power of the storage nodes used by some modern file systems. To achieve both objec- tives, Active Storage allows certain processing tasks to be performed directly on the storage nodes, near the data they manage. However, Active Storage must also support key requirements of scientific applications. In particular, Active Storage must be able to support striped files and files with complex formats (e.g., netCDF). In this paper, we describe how these important requirements can be addressed. The experimental results on a Lustre file system not only show that our proposal can re- duce the network traffic to near zero and scale the performance with the number of storage nodes, but also that it provides an efficient treatment of striped files and can manage files with complex data structures.

  20. High quality mask storage in an advanced Logic-Fab

    NASA Astrophysics Data System (ADS)

    Jähnert, Carmen; Fritsche, Silvio

    2012-02-01

    High efficient mask logistics as well as safe and high quality mask storage are essential requirements within an advanced lithography area of a modern logic waferfab. Fast operational availability of the required masks at the exposure tool with excellent mask condition requires a safe mask handling, safeguarding of high mask quality over the whole mask usage time without any quality degradation and an intelligent mask logistics. One big challenge is the prevention of haze on high advanced phase shift masks used in a high volume production line for some thousands of 248nm or 193nm exposures. In 2008 Infineon Dresden qualified a customer specific developed semi-bare mask storage system from DMSDynamic Micro Systems in combination with a high advanced mask handling and an interconnected complex logistic system. This high-capacity mask storage system DMS M1900.22 for more than 3000 masks with fully automated mask and box handling as well as full-blown XCDA purge has been developed and adapted to the Infineon Lithotoollandscape using Nikon and SMIF reticle cases. Advanced features for ESD safety and mask security, mask tracking via RFID and interactions with the exposure tools were developed and implemented. The stocker is remote controlled by the iCADA-RSM system, ordering of the requested mask directly from the affected exposure tool allows fast access. This paper discusses the advantages and challenges for this approach as well as the practical experience gained during the implementation of the new system which improves the fab performance with respect to mask quality, security and throughput. Especially the realization of an extremely low and stable humidity level in addition with a well controlled air flow at each mask surface, preventing masks from haze degradation and particle contamination, turns out to be a notable technical achievement. The longterm stability of haze critical masks has been improved significantly. Relevant environmental parameters like

  1. The ADIS advanced data acquisition, imaging, and storage system

    SciTech Connect

    Flaherty, J.W.

    1986-01-01

    The design and development of Automated Ultrasonic Scanning Systems (AUSS) by McDonnell Aircraft Company has provided the background for the development of the ADIS advanced data acquisition, imaging, and storage system. The ADIS provides state-of-the-art ultrasonic data processing and imaging features which can be utilized in both laboratory and production line composite evaluation applications. System features, such as, real-time imaging, instantaneous electronic rescanning, multitasking capability, histograms, and cross-sections, provide the tools necessary to inspect and evaluate composite parts quickly and consistently.

  2. Integrated Refrigeration and Storage for Advanced Liquid Hydrogen Operations

    NASA Technical Reports Server (NTRS)

    Swanger, A. M.; Notardonato, W. U.; Johnson, W. L.; Tomsik, T. M.

    2016-01-01

    NASA has used liquefied hydrogen (LH2) on a large scale since the beginning of the space program as fuel for the Centaur and Apollo upper stages, and more recently to feed the three space shuttle main engines. The LH2 systems currently in place at the Kennedy Space Center (KSC) launch pads are aging and inefficient compared to the state-of-the-art. Therefore, the need exists to explore advanced technologies and operations that can drive commodity costs down, and provide increased capabilities. The Ground Operations Demonstration Unit for Liquid Hydrogen (GODU-LH2) was developed at KSC to pursue these goals by demonstrating active thermal control of the propellant state by direct removal of heat using a cryocooler. The project has multiple objectives including zero loss storage and transfer, liquefaction of gaseous hydrogen, and densification of liquid hydrogen. The key technology challenge was efficiently integrating the cryogenic refrigerator into the LH2 storage tank. A Linde LR1620 Brayton cycle refrigerator is used to produce up to 900W cooling at 20K, circulating approximately 22 g/s gaseous helium through the hydrogen via approximately 300 m of heat exchanger tubing. The GODU-LH2 system is fully operational, and is currently under test. This paper will discuss the design features of the refrigerator and storage system, as well as the current test results.

  3. End-to-End Performance Management for Large Distributed Storage

    SciTech Connect

    Almadena Chtchelkanova

    2012-03-18

    Storage systems for large distributed clusters of computer servers are themselves large and distributed. Their complexity and scale make it hard to ensure that applications using them get good, predictable performance. At the same time, shared access to the system from multiple applications, users, and internal system activities leads to a need for predictable performance. This research investigates mechanisms for improving storage system performance in large distributed storage systems through mechanisms that integrate the performance aspects of the path that I/O operations take through the system, from the application interface on the compute server, through the network, to the storate servers. The research focuses on five parts of the I/O path in a distributed storage system: I/O scheduling at the storage server, storage server cache management, client-to-server network flow control, client-to-server connection management, and client cache management.

  4. Underground natural gas storage reservoir management

    SciTech Connect

    Ortiz, I.; Anthony, R.

    1995-06-01

    The objective of this study is to research technologies and methodologies that will reduce the costs associated with the operation and maintenance of underground natural gas storage. This effort will include a survey of public information to determine the amount of natural gas lost from underground storage fields, determine the causes of this lost gas, and develop strategies and remedial designs to reduce or stop the gas loss from selected fields. Phase I includes a detailed survey of US natural gas storage reservoirs to determine the actual amount of natural gas annually lost from underground storage fields. These reservoirs will be ranked, the resultant will include the amount of gas and revenue annually lost. The results will be analyzed in conjunction with the type (geologic) of storage reservoirs to determine the significance and impact of the gas loss. A report of the work accomplished will be prepared. The report will include: (1) a summary list by geologic type of US gas storage reservoirs and their annual underground gas storage losses in ft{sup 3}; (2) a rank by geologic classifications as to the amount of gas lost and the resultant lost revenue; and (3) show the level of significance and impact of the losses by geologic type. Concurrently, the amount of storage activity has increased in conjunction with the net increase of natural gas imports as shown on Figure No. 3. Storage is playing an ever increasing importance in supplying the domestic energy requirements.

  5. Battery Energy Storage System (BESS) and Battery Management System (BMS) for Grid-Scale Applications

    SciTech Connect

    Lawder, M. T.; Suthar, B.; Northrop, P. W. C.; De, S.; Hoff, C. M.; Leitermann, O.; Crow, M. L.; Santhanagopalan, S.; Subramanian, V. R.

    2014-05-07

    The current electric grid is an inefficient system that wastes significant amounts of the electricity it produces because there is a disconnect between the amount of energy consumers require and the amount of energy produced from generation sources. Power plants typically produce more power than necessary to ensure adequate power quality. By taking advantage of energy storage within the grid, many of these inefficiencies can be removed. Advanced modeling is required when using battery energy storage systems (BESS) for grid storage in order to accurately monitor and control the storage system. Battery management systems (BMS) control how the storage system will be used and a BMS that utilizes advanced physics-based models will offer for much more robust operation of the storage system. The paper outlines the current state of the art for modeling in BMS and the advanced models required to fully utilize BMS for both lithium-ion batteries and vanadium redox-flow batteries. In addition, system architecture and how it can be useful in monitoring and control is discussed. A pathway for advancing BMS to better utilize BESS for grid-scale applications is outlined.

  6. Carbon-based electrocatalysts for advanced energy conversion and storage

    PubMed Central

    Zhang, Jintao; Xia, Zhenhai; Dai, Liming

    2015-01-01

    Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) play curial roles in electrochemical energy conversion and storage, including fuel cells and metal-air batteries. Having rich multidimensional nanoarchitectures [for example, zero-dimensional (0D) fullerenes, 1D carbon nanotubes, 2D graphene, and 3D graphite] with tunable electronic and surface characteristics, various carbon nanomaterials have been demonstrated to act as efficient metal-free electrocatalysts for ORR and OER in fuel cells and batteries. We present a critical review on the recent advances in carbon-based metal-free catalysts for fuel cells and metal-air batteries, and discuss the perspectives and challenges in this rapidly developing field of practical significance. PMID:26601241

  7. Carbon-based electrocatalysts for advanced energy conversion and storage.

    PubMed

    Zhang, Jintao; Xia, Zhenhai; Dai, Liming

    2015-08-01

    Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) play curial roles in electrochemical energy conversion and storage, including fuel cells and metal-air batteries. Having rich multidimensional nanoarchitectures [for example, zero-dimensional (0D) fullerenes, 1D carbon nanotubes, 2D graphene, and 3D graphite] with tunable electronic and surface characteristics, various carbon nanomaterials have been demonstrated to act as efficient metal-free electrocatalysts for ORR and OER in fuel cells and batteries. We present a critical review on the recent advances in carbon-based metal-free catalysts for fuel cells and metal-air batteries, and discuss the perspectives and challenges in this rapidly developing field of practical significance. PMID:26601241

  8. Rechargeable dual-metal-ion batteries for advanced energy storage.

    PubMed

    Yao, Hu-Rong; You, Ya; Yin, Ya-Xia; Wan, Li-Jun; Guo, Yu-Guo

    2016-04-14

    Energy storage devices are more important today than any time before in human history due to the increasing demand for clean and sustainable energy. Rechargeable batteries are emerging as the most efficient energy storage technology for a wide range of portable devices, grids and electronic vehicles. Future generations of batteries are required to have high gravimetric and volumetric energy, high power density, low price, long cycle life, high safety and low self-discharge properties. However, it is quite challenging to achieve the above properties simultaneously in state-of-the-art single metal ion batteries (e.g. Li-ion batteries, Na-ion batteries and Mg-ion batteries). In this contribution, hybrid-ion batteries in which various metal ions simultaneously engage to store energy are shown to provide a new perspective towards advanced energy storage: by connecting the respective advantages of different metal ion batteries they have recently attracted widespread attention due to their novel performances. The properties of hybrid-ion batteries are not simply the superposition of the performances of single ion batteries. To enable a distinct description, we only focus on dual-metal-ion batteries in this article, for which the design and the benefits are briefly discussed. We enumerate some new results about dual-metal-ion batteries and demonstrate the mechanism for improving performance based on knowledge from the literature and experiments. Although the search for hybrid-ion batteries is still at an early age, we believe that this strategy would be an excellent choice for breaking the inherent disadvantages of single ion batteries in the near future. PMID:26996438

  9. Energy storage management system with distributed wireless sensors

    SciTech Connect

    Farmer, Joseph C.; Bandhauer, Todd M.

    2015-12-08

    An energy storage system having a multiple different types of energy storage and conversion devices. Each device is equipped with one or more sensors and RFID tags to communicate sensor information wirelessly to a central electronic management system, which is used to control the operation of each device. Each device can have multiple RFID tags and sensor types. Several energy storage and conversion devices can be combined.

  10. Advanced technologies in trauma critical care management.

    PubMed

    Cannon, Jeremy W; Chung, Kevin K; King, David R

    2012-08-01

    Care of critically injured patients has evolved over the 50 years since Shoemaker established one of the first trauma units at Cook County Hospital in 1962. Modern trauma intensive care units offer a high nurse-to-patient ratio, physicians and midlevel providers who manage the patients, and technologically advanced monitors and therapeutic devices designed to optimize the care of patients. This article describes advances that have transformed trauma critical care, including bedside ultrasonography, novel patient monitoring techniques, extracorporeal support, and negative pressure dressings. It also discusses how to evaluate the safety and efficacy of future advances in trauma critical care. PMID:22850154

  11. Advances in managing hepatocellular carcinoma.

    PubMed

    Reataza, Marielle; Imagawa, David K

    2014-06-01

    Multiple modalities for treatment of hepatocellular carcinoma are available, depending on tumor size and number. Surgical resection remains the gold standard, so long as the residual liver function reserve is sufficient. In patients with advanced cirrhosis, liver transplantation is the preferred option, as these patients may not have adequate hepatic reserve after resection. Salvage liver transplantation has also become an option for a select few patients who recur after surgical resection. Ablative techniques have been used for palliation as well as to either completely destroy the tumor, act as an adjunct to resection, or downstage the tumor to meet Milan criteria such that a patient may be a candidate for liver transplantation. Radiofrequency ablation, microwave ablation, chemoembolization, radioembolization, and irreversible electroporation have all been used in this capacity. Currently, sorafenib is the only US Food and Drug Administration-approved chemotherapeutic for hepatocellular carcinoma. The efficacy of sorafenib, in combination with other agents, transarterial chemoembolization, and surgical resection is currently being investigated. Sunitinib and brivanib, tyrosine kinase inhibitors, have failed as potential first- or second-line options for chemotherapy. Bevacizumab in combination with erlotinib is also currently being studied. Final analysis for ramucirumab and axitinib are pending. Tivantinib, a selective mesenchymal-epithelial transition factor (MET) inhibitor, is also undergoing clinical trials for efficacy in MET-high tumors. This review serves to emphasize the current and new technologies emerging in the treatment of hepatocellular carcinoma. PMID:24810646

  12. Thermoelectric Devices Advance Thermal Management

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Thermoelectric (TE) devices heat, cool, and generate electricity when a temperature differential is provided between the two module faces. In cooperation with NASA, Chico, California-based United States Thermoelectric Consortium Inc. (USTC) built a gas emissions analyzer (GEA) for combustion research. The GEA precipitated hydrocarbon particles, preventing contamination that would hinder precise rocket fuel analysis. The USTC research and design team uses patent-pending dimple, pin-fin, microchannel and microjet structures to develop and design heat dissipation devices on the mini-scale level, which not only guarantee high performance of products, but also scale device size from 1 centimeter to 10 centimeters. USTC continues to integrate the benefits of TE devices in its current line of thermal management solutions and has found the accessibility of NASA technical research to be a valuable, sustainable resource that has continued to positively influence its product design and manufacturing

  13. Evaluation of thermal energy storage materials for advanced compressed air energy storage systems

    SciTech Connect

    Zaloudek, F.R.; Wheeler, K.R.; Marksberry, L.

    1983-03-01

    Advanced Compressed-Air Energy Storage (ACAS) plants have the near-term potential to reduce the fuel consumption of compressed-air plants from 33 to 100%, depending upon their design. Fuel is saved by storing some or all of the heat of compression as sensible heat which is subsequently used to reheat the compressed air prior to expansion in the turbine generator. The thermal storage media required for this application must be low cost and durable. The objective of this project was to screen thermal store materials based on their thermal cycle durability, particulate formation and corrosion resistant characteristics. The materials investigated were iron oxide pellets, Denstone pebbles, cast-iron balls, and Dresser basalt rock. The study specifically addressed the problems of particle formation and thermal ratcheting of the materials during thermal cycling and the chemical attack on the materials by the high temperature and moist environment in an ACAS heat storage bed. The results indicate that from the durability standpoint Denstone, cast iron containing 27% or more chromium, and crushed Dresser basalt would possibly stand up to ACAS conditions. If costs are considered in addition to durability and performance, the crushed Dresser basalt would probably be the most desirable heat storage material for adiabatic and hybrid ACAS plants, and more in-depth longer term thermal cycling and materials testing of Dresser basalt is recommended. Also recommended is the redesign and costing analysis of both the hybrid and adiabatic ACAS facilities based upon the use of Dresser basalt as the thermal store material.

  14. Advanced Redox Flow Batteries for Stationary Electrical Energy Storage

    SciTech Connect

    Li, Liyu; Kim, Soowhan; Xia, Guanguang; Wang, Wei; Yang, Zhenguo

    2012-03-19

    This report describes the status of the advanced redox flow battery research being performed at Pacific Northwest National Laboratories for the U.S. Department of Energy’s Energy Storage Systems Program. The Quarter 1 of FY2012 Milestone was completed on time. The milestone entails completion of evaluation and optimization of single cell components for the two advanced redox flow battery electrolyte chemistries recently developed at the lab, the all vanadium (V) mixed acid and V-Fe mixed acid solutions. All the single cell components to be used in future kW-scale stacks have been identified and optimized in this quarter, which include solution electrolyte, membrane or separator; carbon felt electrode and bi-polar plate. Varied electrochemical, chemical and physical evaluations were carried out to assist the component screening and optimization. The mechanisms of the battery capacity fading behavior for the all vanadium redox flow and the Fe/V battery were discovered, which allowed us to optimize the related cell operation parameters and continuously operate the system for more than three months without any capacity decay.

  15. Advanced materials and concepts for energy storage devices

    NASA Astrophysics Data System (ADS)

    Teng, Shiang Jen

    Over the last decade, technological progress and advances in the miniaturization of electronic devices have increased demands for light-weight, high-efficiency, and carbon-free energy storage devices. These energy storage devices are expected to play important roles in automobiles, the military, power plants, and consumer electronics. Two main types of electrical energy storage systems studied in this research are Li ion batteries and supercapacitors. Several promising solid state electrolytes and supercapacitor electrode materials are investigated in this research. The first section of this dissertation is focused on the novel results on pulsed laser annealing of Li7La3Zr2O12 (LLZO). LLZO powders with a tetragonal structure were prepared by a sol-gel technique, then a pulsed laser annealing process was employed to convert the tetragonal powders to cubic LLZO without any loss of lithium. The second section of the dissertation reports on how Li5La 3Nb2O12 (LLNO) was successfully synthesized via a novel molten salt synthesis (MSS) method at the relatively low temperature of 900°C. The low sintering temperature prevented the loss of lithium that commonly occurs during synthesis using conventional solid state or wet chemical reactions. The second type of energy storage device studied is supercapacitors. Currently, research on supercapacitors is focused on increasing their energy densities and lowering their overall production costs by finding suitable electrode materials. The third section of this dissertation details how carbonized woods electrodes were used as supercapacitor electrode materials. A high energy density of 45.6 Wh/kg and a high power density of 2000 W/kg were obtained from the supercapacitor made from carbonized wood electrodes. The high performance of the supercapacitor was discovered to originate from the hierarchical porous structures of the carbonized wood. Finally, the fourth section of this dissertation is on the electrochemical effects of

  16. Waste management and the land disposal restriction storage prohibition

    SciTech Connect

    1992-05-01

    RCRA Sect. 3004(j) prohibits storage of wastes that have been prohibited from land disposal, unless that storage is for the purpose of accumulating sufficient quantities of hazardous wastes to facilitate proper recovery, treatment, or disposal. This requirement was incorporated as part of the Land Disposal Restriction (LDR) regulations. Under the LDR storage prohibition, facilities may only store restricted wastes in containers and tanks. As stated in the Third LDR rule, storage of prohibited waste is only allowed in non-land based storage units since land-based storage is a form of disposal. The EPA has recognized that generators and storers of radioactive mixed waste (RMW) may find it impossible to comply with storage prohibition in cases where no available treatment capacity exists. Additionally, under the current regulatory interpretation, there is no provision that would allow for storage of wastes for which treatment capacity and capability are not available, even where capacity is legitimately being developed. Under the LDR program, restricted wastes that are disposed of, or placed into storage before an LDR effective date, are not subject to the LDR requirements. However, if such wastes are removed from a storage or disposal site after the effective date, such wastes would be subject to LDR requirements. The purpose of this information brief is to clarify what waste management practices constitute removal from storage.

  17. Microprocessor controlled advanced battery management systems

    NASA Technical Reports Server (NTRS)

    Payne, W. T.

    1978-01-01

    The advanced battery management system described uses the capabilities of an on-board microprocessor to: (1) monitor the state of the battery on a cell by cell basis; (2) compute the state of charge of each cell; (3) protect each cell from reversal; (4) prevent overcharge on each individual cell; and (5) control dual rate reconditioning to zero volts per cell.

  18. Advances in Management of Acute Pancreatitis.

    PubMed

    Janisch, Nigeen H; Gardner, Timothy B

    2016-03-01

    This article reviews advances in the management of acute pancreatitis. Medical treatment has been primarily supportive for this diagnosis, and despite extensive research efforts, there are no pharmacologic therapies that improve prognosis. The current mainstay of management, notwithstanding the ongoing debate regarding the volume, fluid type, and rate of administration, is aggressive intravenous fluid resuscitation. Although antibiotics were used consistently for prophylaxis in severe acute pancreatitis to prevent infection, they are no longer used unless infection is documented. Enteral nutrition, especially in patients with severe acute pancreatitis, is considered a cornerstone in management of this disease. PMID:26895677

  19. Recent advances in understanding and managing asthma.

    PubMed

    Loo, Su-Ling; Wark, Peter A B

    2016-01-01

    This review highlights the important articles published in the area of asthma research from January 2015 to July 2016. In basic science, significant advances have been made in understanding the link between the innate immune response and type II acquired immune responses in asthma and the role of the airway epithelium. Novel information continues to emerge with regard to the pathogenesis and heterogeneity of severe asthma. There have been important translational clinical trials in the areas of childhood asthma, treatment of allergy to improve asthma outcomes, and improving drug delivery to optimize the management of asthma. In addition, there are increasing data concerning the application of biological agents to the management of severe asthma. This body of work discusses the most notable advances in the understanding and management of asthma. PMID:27610226

  20. Recent advances in understanding and managing asthma

    PubMed Central

    Loo, Su-Ling; Wark, Peter A.B.

    2016-01-01

    This review highlights the important articles published in the area of asthma research from January 2015 to July 2016. In basic science, significant advances have been made in understanding the link between the innate immune response and type II acquired immune responses in asthma and the role of the airway epithelium. Novel information continues to emerge with regard to the pathogenesis and heterogeneity of severe asthma. There have been important translational clinical trials in the areas of childhood asthma, treatment of allergy to improve asthma outcomes, and improving drug delivery to optimize the management of asthma. In addition, there are increasing data concerning the application of biological agents to the management of severe asthma. This body of work discusses the most notable advances in the understanding and management of asthma. PMID:27610226

  1. Notes on a storage manager for the Clouds kernel

    NASA Technical Reports Server (NTRS)

    Pitts, David V.; Spafford, Eugene H.

    1986-01-01

    The Clouds project is research directed towards producing a reliable distributed computing system. The initial goal is to produce a kernel which provides a reliable environment with which a distributed operating system can be built. The Clouds kernal consists of a set of replicated subkernels, each of which runs on a machine in the Clouds system. Each subkernel is responsible for the management of resources on its machine; the subkernal components communicate to provide the cooperation necessary to meld the various machines into one kernel. The implementation of a kernel-level storage manager that supports reliability is documented. The storage manager is a part of each subkernel and maintains the secondary storage residing at each machine in the distributed system. In addition to providing the usual data transfer services, the storage manager ensures that data being stored survives machine and system crashes, and that the secondary storage of a failed machine is recovered (made consistent) automatically when the machine is restarted. Since the storage manager is part of the Clouds kernel, efficiency of operation is also a concern.

  2. Sol-gel Technology and Advanced Electrochemical Energy Storage Materials

    NASA Technical Reports Server (NTRS)

    Chu, Chung-tse; Zheng, Haixing

    1996-01-01

    Advanced materials play an important role in the development of electrochemical energy devices such as batteries, fuel cells, and electrochemical capacitors. The sol-gel process is a versatile solution for use in the fabrication of ceramic materials with tailored stoichiometry, microstructure, and properties. This processing technique is particularly useful in producing porous materials with high surface area and low density, two of the most desirable characteristics for electrode materials. In addition,the porous surface of gels can be modified chemically to create tailored surface properties, and inorganic/organic micro-composites can be prepared for improved material performance device fabrication. Applications of several sol-gel derived electrode materials in different energy storage devices are illustrated in this paper. V2O5 gels are shown to be a promising cathode material for solid state lithium batteries. Carbon aerogels, amorphous RuO2 gels and sol-gel derived hafnium compounds have been studied as electrode materials for high energy density and high power density electrochemical capacitors.

  3. Recent advances in gene therapy for lysosomal storage disorders

    PubMed Central

    Rastall, David PW; Amalfitano, Andrea

    2015-01-01

    Lysosomal storage disorders (LSDs) are a group of genetic diseases that result in metabolic derangements of the lysosome. Most LSDs are due to the genetic absence of a single catabolic enzyme, causing accumulation of the enzyme’s substrate within the lysosome. Over time, tissue-specific substrate accumulations result in a spectrum of symptoms and disabilities that vary by LSD. LSDs are promising targets for gene therapy because delivery of a single gene into a small percentage of the appropriate target cells may be sufficient to impact the clinical course of the disease. Recently, there have been several significant advancements in the potential for gene therapy of these disorders, including the first human trials. Future clinical trials will build upon these initial attempts, with an improved understanding of immune system responses to gene therapy, the obstacle that the blood–brain barrier poses for neuropathic LSDs, as well other biological barriers that, when overcome, may facilitate gene therapy for LSDs. In this manuscript, we will highlight the recent innovations in gene therapy for LSDs and discuss the clinical limitations that remain to be overcome, with the goal of fostering an understanding and further development of this important field. PMID:26170711

  4. Recent Advances in Managing Acute Pancreatitis

    PubMed Central

    Janisch, Nigeen; Gardner, Timothy

    2015-01-01

    This article will review the recent advances in managing acute pancreatitis. Supportive care has long been the standard of treatment for this disease despite extensive, but ultimately unsuccessful, efforts to develop disease-specific pharmacologic therapies. The primary interventions center on aggressive fluid resuscitation, initiation of early enteral nutrition, targeted antibiotic therapy, and the management of complications. In this article, we will detail treatment of acute pancreatitis with a focus on intravenous fluid resuscitation, enteral feeding, and the current evidence behind the use of antibiotics and other pharmacologic therapies. PMID:26918139

  5. Advanced channel monitoring for optical layer management

    NASA Astrophysics Data System (ADS)

    Yang, Weiguo; Zheng, Zheng

    2003-12-01

    We categorized synchronous optical network (SONET) operations, administration, maintenance, and provisioning (OAM&P) requirements according to their time urgency as related to the network operation and assigned them to a three-layer telecommunications management network for transparent networks accordingly. Because all-optical bit-by-bit processing at data rates is not yet available, a solution that is currently feasible for optical management layer requirements is proposed on the basis of a previously demonstrated advanced channel-monitoring method. Indicators for signal quality as well as channel use can be provided, and the scheme is transparent to current SONET network elements.

  6. Recent advances in the management of acromegaly

    PubMed Central

    Ntali, Georgia; Karavitaki, Niki

    2015-01-01

    Acromegaly is a rare condition of GH excess associated with significant morbidities (e.g. hypertension, glucose intolerance or diabetes mellitus, cardiac, cerebrovascular, respiratory disease and arthritis) and, when uncontrolled, high mortality. Surgery, medical treatment and radiotherapy remain our therapeutic tools. Advances in these options during the last years have offered further perspectives in the management of patients and particularly those with challenging tumours; the impact of these on the long-term morbidity and mortality remains to be assessed. PMID:26918140

  7. Advanced thermal management technologies for defense electronics

    NASA Astrophysics Data System (ADS)

    Bloschock, Kristen P.; Bar-Cohen, Avram

    2012-05-01

    Thermal management technology plays a key role in the continuing miniaturization, performance improvements, and higher reliability of electronic systems. For the past decade, and particularly, the past 4 years, the Defense Advanced Research Projects Agency (DARPA) has aggressively pursued the application of micro- and nano-technology to reduce or remove thermal constraints on the performance of defense electronic systems. The DARPA Thermal Management Technologies (TMT) portfolio is comprised of five technical thrust areas: Thermal Ground Plane (TGP), Microtechnologies for Air-Cooled Exchangers (MACE), NanoThermal Interfaces (NTI), Active Cooling Modules (ACM), and Near Junction Thermal Transport (NJTT). An overview of the TMT program will be presented with emphasis on the goals and status of these efforts relative to the current State-of-the-Art. The presentation will close with future challenges and opportunities in the thermal management of defense electronics.

  8. Storage tanks -- Advances in environmental control technology series

    SciTech Connect

    Cheremisinoff, P.N.

    1996-10-01

    This volume helps in identifying and assessing problems regarding the technical issues as well as regulatory requirements regarding storage tank use, replacement, and remediation. The volume is divided into ten chapters dealing with aboveground and underground storage tanks composition; underground storage tanks; aboveground tanks; aboveground storage tanks regulations and engineering; aboveground tank farm specifications; a comparison of steel and fiberglass construction for underground storage tanks; fuel dispensing tanks--factors to consider in location; a comparison of steel fiber-glass construction; air stripping VOCs from groundwater; and minimizing ecological damage during cleanup of terrestrial and wetland oil spills. It should be found useful as an up-to-date reference to concerned engineers, technicians, scientists, and contractors.

  9. Spent fuel storage and waste management fuel cycle optimization using CAFCA

    SciTech Connect

    Brinton, S.; Kazimi, M.

    2013-07-01

    Spent fuel storage modeling is at the intersection of nuclear fuel cycle system dynamics and waste management policy. A model that captures the economic parameters affecting used nuclear fuel storage location options, which complements fuel cycle economic assessment has been created using CAFCA (Code for Advanced Fuel Cycles Assessment) of MIT. Research has also expanded to the study on dependency of used nuclear fuel storage economics, environmental impact, and proliferation risk. Three options of local, regional, and national storage were studied. The preliminary product of this research is the creation of a system dynamics tool known as the Waste Management Module which provides an easy to use interface for education on fuel cycle waste management economic impacts. Storage options costs can be compared to literature values with simple variation available for sensitivity study. Additionally, a first of a kind optimization scheme for the nuclear fuel cycle analysis is proposed and the applications of such an optimization are discussed. The main tradeoff for fuel cycle optimization was found to be between economics and most of the other identified metrics. (authors)

  10. Advanced chemical hydride-based hydrogen generation/storage system for fuel cell vehicles

    SciTech Connect

    Breault, R.W.; Rolfe, J.

    1998-08-01

    Because of the inherent advantages of high efficiency, environmental acceptability, and high modularity, fuel cells are potentially attractive power supplies. Worldwide concerns over clean environments have revitalized research efforts on developing fuel cell vehicles (FCV). As a result of intensive research efforts, most of the subsystem technology for FCV`s are currently well established. These include: high power density PEM fuel cells, control systems, thermal management technology, and secondary power sources for hybrid operation. For mobile applications, however, supply of hydrogen or fuel for fuel cell operation poses a significant logistic problem. To supply high purity hydrogen for FCV operation, Thermo Power`s Advanced Technology Group is developing an advanced hydrogen storage technology. In this approach, a metal hydride/organic slurry is used as the hydrogen carrier and storage media. At the point of use, high purity hydrogen will be produced by reacting the metal hydride/organic slurry with water. In addition, Thermo Power has conceived the paths for recovery and regeneration of the spent hydride (practically metal hydroxide). The fluid-like nature of the spent hydride/organic slurry will provide a unique opportunity for pumping, transporting, and storing these materials. The final product of the program will be a user-friendly and relatively high energy storage density hydrogen supply system for fuel cell operation. In addition, the spent hydride can relatively easily be collected at the pumping station and regenerated utilizing renewable sources, such as biomass, natural, or coal, at the central processing plants. Therefore, the entire process will be economically favorable and environmentally friendly.

  11. Advanced solar thermal storage medium test data and analysis

    NASA Technical Reports Server (NTRS)

    Saha, H.

    1981-01-01

    A comparative study has been made of experimentally obtained heat transfer and heat storage characteristics of a solar thermal energy storage bed utilizing containerized water or phase change material (PCM) and rock or brick. It is shown that (1) containers with an L/D ratio of 0.80 and a mass/surface area ratio of 2.74 in a random stacking arrangement have the optimum heat transfer characteristics; and (2) vertical stacking has the least pressure drop across the test bed. It is also found that standard bricks with appropriate holes make an excellent storage medium.

  12. Inertial energy storage for advanced space station applications

    NASA Technical Reports Server (NTRS)

    Van Tassel, K. E.; Simon, W. E.

    1985-01-01

    Because the NASA Space Station will spend approximately one-third of its orbital time in the earth's shadow, depriving it of solar energy and requiring an energy storage system to meet system demands, attention has been given to flywheel energy storage systems. These systems promise high mechanical efficiency, long life, light weight, flexible design, and easily monitored depth of discharge. An assessment is presently made of three critical technology areas: rotor materials, magnetic suspension bearings, and motor-generators for energy conversion. Conclusions are presented regarding the viability of inertial energy storage systems and of problem areas requiring further technology development efforts.

  13. Management accounting for advanced technological environments.

    PubMed

    Kaplan, R S

    1989-08-25

    Management accounting systems designed decades ago no longer provide timely, relevant information for companies in today's highly competitive environment. New operational control and performance measurement systems are recognizing the importance of direct measurement of quality, manufacturing lead times, flexibility, and customer responsiveness, as well as more accurate measures of the actual costs of consumed resources. Activity-based cost systems can assign the costs of indirect and support resources to the specific products and activities that benefit from these resources. Both operational control and activity-based systems represent new opportunities for improved managerial information in complex, technologically advanced environments. PMID:17773356

  14. Advanced Thermal Storage System with Novel Molten Salt: December 8, 2011 - April 30, 2013

    SciTech Connect

    Jonemann, M.

    2013-05-01

    Final technical progress report of Halotechnics Subcontract No. NEU-2-11979-01. Halotechnics has demonstrated an advanced thermal energy storage system with a novel molten salt operating at 700 degrees C. The molten salt and storage system will enable the use of advanced power cycles such as supercritical steam and supercritical carbon dioxide in next generation CSP plants. The salt consists of low cost, earth abundant materials.

  15. Use belowground storage tanks to manage stormwater

    SciTech Connect

    Nedrow, J.

    1996-01-01

    To meet performance and operating requirements under Resource Conservation and Recovery Act (RCRA), BP Oil`s Toledo Refinery installed two 10-million-gallon (MMgal) concrete belowground storage tanks to replace the existing impoundment ponds. Environmental, safety and operating criteria influenced how this older refinery could cost-effectively replace impoundment ponds without interrupting the production schedule. The north stormwater impoundment pond at BP Oil`s Toledo Refinery had received primary sludge, a RCRA-listed hazardous waste and material exceeding the toxic characteristic limit for benzene (0.5 ppm). Because the pond could not be adapted to meet RCRA standards, it had to be replaced by a system that met these standards and New Source Performance Standards (NSPS). Under normal operating conditions, stormwater was commingled with process wastewater and processed at the wastewater treatment unit (WWTU) before final disposal. However, when flow in the sewer system exceeded the capacity of the WWTU, excess flow was stored in an impoundment system. The case history shows how BP Oil`s project engineers, working with a consulting engineering group and a general contractor (GC), cost-effectively replaced the impoundment pond to handle stormwater runoff for the refinery.

  16. Management of a complex cavern storage facility for natural gas

    SciTech Connect

    1998-04-01

    The Epe cavern storage facility operated by Ruhrgas AG has developed into one of the largest gas cavern storage facilities in the world. Currently, there are 32 caverns and 18 more are planned in the future. Working gas volume will increase from approximately 1.5 {times} 10{sup 9} to 2 {times} 10{sup 9} m{sup 3}. The stratified salt deposit containing the caverns has a surface area of approximately 7 km{sup 2} and is 250 m thick at the edge and 400 m thick in the center. Caverns are leached by a company that uses the recovered brine in the chlorine industry. Cavern dimensions are determined before leaching. The behavior of each cavern, as well as the thermodynamic properties of natural gas must be considered in cavern management. The full-length paper presents the components of a complex management system covering the design, construction, and operation of the Epe gas-storage caverns.

  17. Insect pest management for raw commodities during storage

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This book chapter provides an overview of the pest management decision-making process during grain storage. An in-depth discussion of sampling methods, cost-benefit analysis, expert systems, consultants and the use of computer simulation models is provided. Sampling is essential to determine if pest...

  18. Science Information Storage and Access: Data Management Using Appleworks.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This report describes a data management process that provides users with a systematic approach to document identification, and to information storage and retrieval using the AppleWorks database subprogram and a simple organizational scheme. The functions of this scheme are described and include: (1) taking the user from general to specific…

  19. Managing Wind-based Electricity Generation and Storage

    NASA Astrophysics Data System (ADS)

    Zhou, Yangfang

    Among the many issues that profoundly affect the world economy every day, energy is one of the most prominent. Countries such as the U.S. strive to reduce reliance on the import of fossil fuels, and to meet increasing electricity demand without harming the environment. Two of the most promising solutions for the energy issue are to rely on renewable energy, and to develop efficient electricity storage. Renewable energy---such as wind energy and solar energy---is free, abundant, and most importantly, does not exacerbate the global warming problem. However, most renewable energy is inherently intermittent and variable, and thus can benefit greatly from coupling with electricity storage, such as grid-level industrial batteries. Grid storage can also help match the supply and demand of an entire electricity market. In addition, electricity storage such as car batteries can help reduce dependence on oil, as it can enable the development of Plug-in Hybrid Electric Vehicles, and Battery Electric Vehicles. This thesis focuses on understanding how to manage renewable energy and electricity storage properly together, and electricity storage alone. In Chapter 2, I study how to manage renewable energy, specifically wind energy. Managing wind energy is conceptually straightforward: generate and sell as much electricity as possible when prices are positive, and do nothing otherwise. However, this leads to curtailment when wind energy exceeds the transmission capacity, and possible revenue dilution when current prices are low but are expected to increase in the future. Electricity storage is being considered as a means to alleviate these problems, and also enables buying electricity from the market for later resale. But the presence of storage complicates the management of electricity generation from wind, and the value of storage for a wind-based generator is not entirely understood. I demonstrate that for such a combined generation and storage system the optimal policy does not

  20. Management of advanced medullary thyroid cancer.

    PubMed

    Hadoux, Julien; Pacini, Furio; Tuttle, R Michael; Schlumberger, Martin

    2016-01-01

    Medullary thyroid cancer arises from calcitonin-producing C-cells and accounts for 3-5% of all thyroid cancers. The discovery of a locally advanced medullary thyroid cancer that is not amenable to surgery or of distant metastases needs careful work-up, including measurement of serum calcitonin and carcinoembryonic antigen (and their doubling times), in addition to comprehensive imaging to determine the extent of the disease, its aggressiveness, and the need for any treatment. In the past, cytotoxic chemotherapy was used for treatment but produced little benefit. For the past 10 years, tyrosine kinase inhibitors targeting vascular endothelial growth factor receptors and RET (rearranged during transfection) have been used when a systemic therapy is indicated for large tumour burden and documented disease progression. Vandetanib and cabozantinib have shown benefits on progression-free survival compared with placebo in this setting, but their toxic effect profiles need thorough clinical management in specialised centres. This Review describes the management and treatment of patients with advanced medullary thyroid cancer with emphasis on current targeted therapies and perspectives to improve patient care. Most treatment responses are transient, emphasising that mechanisms of resistance need to be better understood and that the efficacy of treatment approaches should be improved with combination therapies or other drugs that might be more potent or target other pathways, including immunotherapy. PMID:26608066

  1. Multidisciplinary management of advanced lung neuroendocrine tumors

    PubMed Central

    Ferolla, Piero; Guerrera, Francesco; Ruffini, Enrico; Travis, William D.; Rossi, Giulio; Lausi, Paolo Olivo; Oliaro, Alberto

    2015-01-01

    The optimal clinical management of aggressive/advanced lung neuroendocrine tumors (NETs) is still debated, due to their rarity and the lack of prospective randomized studies. Results derive from retrospective mono-Institutional series, and few dedicated prospective trials, recently designed, are still ongoing. In low-grade tumors [bronchial carcinoids (BCs)] surgery, whenever feasible, remains the mainstay of treatment, and chemo/radiotherapy (RT) should be reserved to progressive diseases (PD). In case of resected N1-N2 BCs, a “watch and see” policy associated with a close clinical/radiological follow-up is recommended. Somatostatin analogs (SSA) seem to be effective in controlling BCs associated endocrine syndromes, while SSA antiproliferative effect has also been reported in the past. Targeted therapy with new drugs (Everolimus) seems to be very promising, but further trials are needed. Surgery alone is not sufficient to treat high-grade NETs: adjuvant CT is required also in early stages. Platinum-Etoposide regimen demonstrated to be the most effective; irinotecan and other biological drugs are considered very promising. In conclusion, the management of advanced lung NETs should be individualized by multidisciplinary teams which include Medical and Radiation Oncologists, Surgeons, Pathologists, Pulmonologists, Endocrinologists, Interventional Radiologists, and the prognosis is mainly dependent on tumor grade and its anatomical extent. PMID:25984363

  2. Advanced onboard storage concepts for natural gas-fueled automotive vehicles

    NASA Technical Reports Server (NTRS)

    Remick, R. J.; Elkins, R. H.; Camara, E. H.; Bulicz, T.

    1984-01-01

    The evaluation of several advanced concepts for storing natural gas at reduced pressure is presented. The advanced concepts include adsorption on high surface area carbon, adsorption in high porosity zeolite, storage in clathration compounds, and storage by dissolution in liquid solvents. High surface area carbons with high packing density are the best low pressure storage mediums. A simple mathematical model is used to compare adsorption storage on a state of the art carbon with compression storage. The model indicates that a vehicle using adsorption storage of natural gas at 3.6 MPa will have 36 percent of the range, on the EPA city cycle, of a vehicle operating on a compression storage system having the same physical size and a peak storage pressure of 21 MPa. Preliminary experiments and current literature suggest that the storage capacity of state of the art carbons could be improved by as much as 50 percent, and that adsorption systems having a capacity equal to compression storage at 14 MPa are possible without exceeding a maximum pressure of 3.6 MPa.

  3. Molten Glass for Thermal Storage: Advanced Molten Glass for Heat Transfer and Thermal Energy Storage

    SciTech Connect

    2012-01-01

    HEATS Project: Halotechnics is developing a high-temperature thermal energy storage system using a new thermal-storage and heat-transfer material: earth-abundant and low-melting-point molten glass. Heat storage materials are critical to the energy storage process. In solar thermal storage systems, heat can be stored in these materials during the day and released at night—when the sun is not out—to drive a turbine and produce electricity. In nuclear storage systems, heat can be stored in these materials at night and released to produce electricity during daytime peak-demand hours. Halotechnics new thermal storage material targets a price that is potentially cheaper than the molten salt used in most commercial solar thermal storage systems today. It is also extremely stable at temperatures up to 1200°C—hundreds of degrees hotter than the highest temperature molten salt can handle. Being able to function at high temperatures will significantly increase the efficiency of turning heat into electricity. Halotechnics is developing a scalable system to pump, heat, store, and discharge the molten glass. The company is leveraging technology used in the modern glass industry, which has decades of experience handling molten glass.

  4. AN ADVANCED CALIBRATION PROCEDURE FOR COMPLEX IMPEDANCE SPECTRUM MEASUREMENTS OF ADVANCED ENERGY STORAGE DEVICES

    SciTech Connect

    William H. Morrison; Jon P. Christophersen; Patrick Bald; John L. Morrison

    2012-06-01

    With the increasing demand for electric and hybrid electric vehicles and the explosion in popularity of mobile and portable electronic devices such as laptops, cell phones, e-readers, tablet computers and the like, reliance on portable energy storage devices such as batteries has likewise increased. The concern for the availability of critical systems in turn drives the availability of battery systems and thus the need for accurate battery health monitoring has become paramount. Over the past decade the Idaho National Laboratory (INL), Montana Tech of the University of Montana (Tech), and Qualtech Systems, Inc. (QSI) have been developing the Smart Battery Status Monitor (SBSM), an integrated battery management system designed to monitor battery health, performance and degradation and use this knowledge for effective battery management and increased battery life. Key to the success of the SBSM is an in-situ impedance measurement system called the Impedance Measurement Box (IMB). One of the challenges encountered has been development of an accurate, simple, robust calibration process. This paper discusses the successful realization of this process.

  5. Spent fuel storage and management in the United Kingdom

    SciTech Connect

    Sills, R.J.

    1989-04-01

    During the past 33 years, fuel of various types have been stored, transported and reprocessed in the United Kingdom. This paper provides an overview of those programs starting from the Magnox stations, through the AGR program and the move to LWR fuel. Throughout this time BNFL has provided services for fuel storage, reprocessing, transportation and the enrichment and fabrication of new fuel. The development of new plants and processes to handle the changing fuel types and the associated waste management schemes will be addressed. A description of future plans for fuel storage and reprocessing is included.

  6. Advanced Energy Storage Life and Health Prognostics (INL)

    SciTech Connect

    Jon P. Christophersen

    2011-11-01

    The objective of this work is to develop methodologies that will accurately estimate state-of-health (SOH) and remaining useful life (RUL) of electrochemical energy storage devices using both offline and online (i.e., in-situ) techniques through: (1) Developing a statistically robust battery life estimator tool based on both testing and simulation, (2) Developing rapid impedance spectrum measurement techniques that enable onboard power assessment, and (3) Developing an energy storage monitoring system that incorporates both passive and active measurements for onboard systems.

  7. Storage and processing evaluation of advanced potato breeding clones

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The accumulation of reducing sugars during cold storage of potato tubers is a serious and costly problem for producers and processors. Most, but not all, currently used potato cultivars are susceptible to cold sweetening and are therefore stored at warmer temperatures that can accelerate disease pr...

  8. Storage/processing performance of advanced potato breeding clones

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The accumulation of reducing sugars during cold storage of potato tubers is a serious and costly problem for producers and processors. Most, but not all, currently used potato cultivars are susceptible to "cold sweetening" and are therefore stored at warmer temperatures that can accelerate disease ...

  9. Advanced Potato Breeding Clones: Storage and Processing Evaluation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The accumulation of reducing sugars during cold storage of potato tubers is a serious and costly problem for producers and processors. Most, but not all, currently used potato cultivars are susceptible to Acold sweetening@ and are therefore stored at warmer temperatures that can accelerate disease ...

  10. Recent advances in understanding and managing rhabdomyosarcoma

    PubMed Central

    Hiniker, Susan M.

    2015-01-01

    Rhabdomyosarcoma is the most common childhood soft tissue sarcoma and the fourth most common pediatric solid tumor. For most patients, treatment consists of a multimodality approach, including chemotherapy, surgery, and/or radiotherapy. To guide treatment, patients with rhabdomyosarcoma are risk stratified based on a number of factors. These factors include clinical group, which depends largely on the extent of resection and nodal involvement, and stage, which takes into account tumor size, invasion, nodal involvement, and disease site. Histology of the tumor and age at diagnosis are also factored into risk stratification. Recent advances in understanding the biology of the disease have allowed for the further sub-classification of rhabdomyosarcoma. In addition, elucidation of additional clinical features associated with poor prognosis has allowed for better understanding of risk and provides more clarity regarding those patients who require more intensive therapy. Many areas of active investigation are ongoing, including the following: further delineation of the biological underpinnings of the various disease subtypes with the possibility of molecularly targeted therapy; a better understanding of clinical risk factors, including the evaluation and management of potentially involved lymph nodes; determination of the appropriate role of post-treatment imaging and assessment of response to therapy; and incorporation of advanced radiotherapeutic techniques, including conformal intensity-modulated photon and proton therapy. PMID:26097732

  11. Key management and encryption under the bounded storage model.

    SciTech Connect

    Draelos, Timothy John; Neumann, William Douglas; Lanzone, Andrew J.; Anderson, William Erik

    2005-11-01

    There are several engineering obstacles that need to be solved before key management and encryption under the bounded storage model can be realized. One of the critical obstacles hindering its adoption is the construction of a scheme that achieves reliable communication in the event that timing synchronization errors occur. One of the main accomplishments of this project was the development of a new scheme that solves this problem. We show in general that there exist message encoding techniques under the bounded storage model that provide an arbitrarily small probability of transmission error. We compute the maximum capacity of this channel using the unsynchronized key-expansion as side-channel information at the decoder and provide tight lower bounds for a particular class of key-expansion functions that are pseudo-invariant to timing errors. Using our results in combination with Dziembowski et al. [11] encryption scheme we can construct a scheme that solves the timing synchronization error problem. In addition to this work we conducted a detailed case study of current and future storage technologies. We analyzed the cost, capacity, and storage data rate of various technologies, so that precise security parameters can be developed for bounded storage encryption schemes. This will provide an invaluable tool for developing these schemes in practice.

  12. Mechanisms Linking Advanced Airway Management and Cardiac Arrest Outcomes

    PubMed Central

    Benoit, Justin L.; Prince, David K.; Wang, Henry E.

    2015-01-01

    Advanced airway management – such as endotracheal intubation (ETI) or supraglottic airway (SGA) insertion – is one of the most prominent interventions in out-of-hospital cardiac arrest (OHCA) resuscitation. While randomized controlled trials are currently in progress to identify the best advanced airway technique in OHCA, the mechanisms by which airway management may influence OHCA outcomes remain unknown. We provide a conceptual model describing potential mechanisms linking advanced airway management with OHCA outcomes. PMID:26073275

  13. Advancing the science of forensic data management

    NASA Astrophysics Data System (ADS)

    Naughton, Timothy S.

    2002-07-01

    Many individual elements comprise a typical forensics process. Collecting evidence, analyzing it, and using results to draw conclusions are all mutually distinct endeavors. Different physical locations and personnel are involved, juxtaposed against an acute need for security and data integrity. Using digital technologies and the Internet's ubiquity, these diverse elements can be conjoined using digital data as the common element. This result is a new data management process that can be applied to serve all elements of the community. The first step is recognition of a forensics lifecycle. Evidence gathering, analysis, storage, and use in legal proceedings are actually just distinct parts of a single end-to-end process, and thus, it is hypothesized that a single data system that can also accommodate each constituent phase using common network and security protocols. This paper introduces the idea of web-based Central Data Repository. Its cornerstone is anywhere, anytime Internet upload, viewing, and report distribution. Archives exist indefinitely after being created, and high-strength security and encryption protect data and ensure subsequent case file additions do not violate chain-of-custody or other handling provisions. Several legal precedents have been established for using digital information in courts of law, and in fact, effective prosecution of cyber crimes absolutely relies on its use. An example is a US Department of Agriculture division's use of digital images to back up its inspection process, with pictures and information retained on secure servers to enforce the Perishable Agricultural Commodities Act. Forensics is a cumulative process. Secure, web-based data management solutions, such as the Central Data Repository postulated here, can support each process step. Logically marrying digital technologies with Internet accessibility should help nurture a thought process to explore alternatives that make forensics data accessible to authorized individuals

  14. Can intensive management increase carbon storage in forests

    SciTech Connect

    Schroeder, P.

    1991-01-01

    A possible response to increasing atmospheric CO2 concentration is to attempt to increase the amount of carbon stored in terrestrial vegetation. One approach to increasing the size of the terrestrial carbon sink is to increase the growth of forests by utilizing intensive forest management practices. The paper uses data from the literature and from forest growth and yield models to analyze the impact of three management practices on carbon storage: thinning, fertilization, and control of competing vegetation. Using Douglas-fir (Pseudotsuga menziesii) and loblolly pine (Pinus taeda) as example species, results showed that thinning generally does not increase carbon storage, and may actually cause a decrease. The exception is thinning of very dense young stands.

  15. Advanced data management system architectures testbed

    NASA Technical Reports Server (NTRS)

    Grant, Terry

    1990-01-01

    The objective of the Architecture and Tools Testbed is to provide a working, experimental focus to the evolving automation applications for the Space Station Freedom data management system. Emphasis is on defining and refining real-world applications including the following: the validation of user needs; understanding system requirements and capabilities; and extending capabilities. The approach is to provide an open, distributed system of high performance workstations representing both the standard data processors and networks and advanced RISC-based processors and multiprocessor systems. The system provides a base from which to develop and evaluate new performance and risk management concepts and for sharing the results. Participants are given a common view of requirements and capability via: remote login to the testbed; standard, natural user interfaces to simulations and emulations; special attention to user manuals for all software tools; and E-mail communication. The testbed elements which instantiate the approach are briefly described including the workstations, the software simulation and monitoring tools, and performance and fault tolerance experiments.

  16. Management of intestinal obstruction in advanced malignancy

    PubMed Central

    Ferguson, Henry John Murray; Ferguson, Claire Irene; Speakman, John; Ismail, Tariq

    2015-01-01

    Patients with incurable, advanced abdominal or pelvic malignancy often present to acute surgical departments with symptoms and signs of intestinal obstruction. It is rare for bowel strangulation to occur in these presentations, and spontaneous resolution often occurs, so the luxury of time should be afforded while decisions are made regarding surgery. Cross-sectional imaging is valuable in determining the underlying mechanism and pathology. The majority of these patients will not be suitable for an operation, and will be best managed in conjunction with a palliative medicine team. Surgeons require a good working knowledge of the mechanisms of action of anti-emetics, anti-secretories and analgesics to tailor early management to individual patients, while decisions regarding potential surgery are made. Deciding if and when to perform operative intervention in this group is complex, and fraught with both technical and emotional challenges. Surgery in this group is highly morbid, with no current evidence available concerning quality of life following surgery. The limited evidence concerning operative strategy suggests that resection and primary anastomosis results in improved survival, over bypass or stoma formation. Realistic prognostication and involvement of the patient, care-givers and the multidisciplinary team in treatment decisions is mandatory if optimum outcomes are to be achieved. PMID:26288731

  17. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Storage and inventory management of donated foods. 250... Donated Foods in Contracts With Food Service Management Companies § 250.52 Storage and inventory... general requirements in § 250.14(b) for the storage and inventory management of donated foods. (b)...

  18. Interdisciplinary Management of Patient with Advanced Periodontal Disease.

    PubMed

    Kochar, Gagan Deep; Jayan, B; Chopra, S S; Mechery, Reenesh; Goel, Manish; Verma, Munish

    2016-01-01

    This case report describes the interdisciplinary management of an adult patient with advanced periodontal disease. Treatment involved orthodontic and periodontal management. Good esthetic results and dental relationships were achieved by the treatment. PMID:27319043

  19. Advanced Management Communication: An Elective Course in Corporate Communication.

    ERIC Educational Resources Information Center

    Argenti, Paul A.

    1986-01-01

    Proposes a college-level elective course in advanced management communication that would teach future managers how to communicate with shareholders, the media, financial analysts, and the labor force. (SRT)

  20. Recent advances in redox flow cell storage systems

    NASA Technical Reports Server (NTRS)

    Thaller, L. H.

    1979-01-01

    Several features which were conceived and incorporated into complete redox systems that greatly enhanced its ability to be kept in proper charge balance, to be capable of internal voltage regulation, and in general be treated as a true multicell electrochemical system rather than an assembly of single cells that were wired together, were discussed. The technology status as it relates to the two application areas of solar photovoltaic/wind and distributed energy storage for electric utility applications was addressed. The cost and life advantages of redox systems were also covered.

  1. Advances in Understanding and Managing Chronic Urticaria

    PubMed Central

    Moolani, Yasmin; Lynde, Charles; Sussman, Gordon

    2016-01-01

    There have been recent advances in the classification and management of chronic urticaria. The new term chronic spontaneous urticaria (CSU) has replaced chronic idiopathic urticaria and chronic autoimmune urticaria. In addition, chronic inducible urticaria (CINDU) has replaced physical urticaria and includes other forms of inducible urticaria, such as cholinergic and aquagenic urticaria. Furthermore, novel research has resulted in a new understanding with guidelines being revised in the past year by both the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA 2LEN)/European Dermatology Forum (EDF)/World Allergy Organization (WAO). There are some differences in the recommendations, which will be discussed, but the core updates are common to both groups. The basic treatment for chronic urticaria involves second-generation non-sedating non-impairing H 1 antihistamines as first-line treatment. This is followed by up to a 4-fold increase in the licensed dose of these H 1 antihistamines. The major therapeutic advance in recent years has been in third-line treatment with omalizumab, a humanized monoclonal anti-immunoglobulin E (anti-IgE) antibody that prevents binding of IgE to the high-affinity IgE receptor. Several multicenter randomized controlled trials have shown safety and efficacy of omalizumab for CSU. There are also some small studies showing efficacy of omalizumab in CINDU. While there were previously many treatment options which were lacking in strong evidence, we are moving into an era where the treatment algorithm for chronic urticaria is simplified and contains more evidence-based, effective, and less toxic treatment options. PMID:26949520

  2. Advances in Understanding and Managing Chronic Urticaria.

    PubMed

    Moolani, Yasmin; Lynde, Charles; Sussman, Gordon

    2016-01-01

    There have been recent advances in the classification and management of chronic urticaria. The new term chronic spontaneous urticaria (CSU) has replaced chronic idiopathic urticaria and chronic autoimmune urticaria. In addition, chronic inducible urticaria (CINDU) has replaced physical urticaria and includes other forms of inducible urticaria, such as cholinergic and aquagenic urticaria. Furthermore, novel research has resulted in a new understanding with guidelines being revised in the past year by both the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA (2)LEN)/European Dermatology Forum (EDF)/World Allergy Organization (WAO). There are some differences in the recommendations, which will be discussed, but the core updates are common to both groups. The basic treatment for chronic urticaria involves second-generation non-sedating non-impairing H 1 antihistamines as first-line treatment. This is followed by up to a 4-fold increase in the licensed dose of these H 1 antihistamines. The major therapeutic advance in recent years has been in third-line treatment with omalizumab, a humanized monoclonal anti-immunoglobulin E (anti-IgE) antibody that prevents binding of IgE to the high-affinity IgE receptor. Several multicenter randomized controlled trials have shown safety and efficacy of omalizumab for CSU. There are also some small studies showing efficacy of omalizumab in CINDU. While there were previously many treatment options which were lacking in strong evidence, we are moving into an era where the treatment algorithm for chronic urticaria is simplified and contains more evidence-based, effective, and less toxic treatment options. PMID:26949520

  3. Microgravity fluid management requirements of advanced solar dynamic power systems

    NASA Technical Reports Server (NTRS)

    Migra, Robert P.

    1987-01-01

    The advanced solar dynamic system (ASDS) program is aimed at developing the technology for highly efficient, lightweight space power systems. The approach is to evaluate Stirling, Brayton and liquid metal Rankine power conversion systems (PCS) over the temperature range of 1025 to 1400K, identify the critical technologies and develop these technologies. Microgravity fluid management technology is required in several areas of this program, namely, thermal energy storage (TES), heat pipe applications and liquid metal, two phase flow Rankine systems. Utilization of the heat of fusion of phase change materials offers potential for smaller, lighter TES systems. The candidate TES materials exhibit large volume change with the phase change. The heat pipe is an energy dense heat transfer device. A high temperature application may transfer heat from the solar receiver to the PCS working fluid and/or TES. A low temperature application may transfer waste heat from the PCS to the radiator. The liquid metal Rankine PCS requires management of the boiling/condensing process typical of two phase flow systems.

  4. Advanced Thermal Storage for Central Receivers with Supercritical Coolants

    SciTech Connect

    Kelly, Bruce D.

    2010-06-15

    The principal objective of the study is to determine if supercritical heat transport fluids in a central receiver power plant, in combination with ceramic thermocline storage systems, offer a reduction in levelized energy cost over a baseline nitrate salt concept. The baseline concept uses a nitrate salt receiver, two-tank (hot and cold) nitrate salt thermal storage, and a subcritical Rankine cycle. A total of 6 plant designs were analyzed, as follows: Plant Designation Receiver Fluid Thermal Storage Rankine Cycle Subcritical nitrate salt Nitrate salt Two tank nitrate salt Subcritical Supercritical nitrate salt Nitrate salt Two tank nitrate salt Supercritical Low temperature H2O Supercritical H2O Two tank nitrate salt Supercritical High temperature H2O Supercritical H2O Packed bed thermocline Supercritical Low temperature CO2 Supercritical CO2 Two tank nitrate salt Supercritical High temperature CO2 Supercritical CO2 Packed bed thermocline Supercritical Several conclusions have been drawn from the results of the study, as follows: 1) The use of supercritical H2O as the heat transport fluid in a packed bed thermocline is likely not a practical approach. The specific heat of the fluid is a strong function of the temperatures at values near 400 °C, and the temperature profile in the bed during a charging cycle is markedly different than the profile during a discharging cycle. 2) The use of supercritical CO2 as the heat transport fluid in a packed bed thermocline is judged to be technically feasible. Nonetheless, the high operating pressures for the supercritical fluid require the use of pressure vessels to contain the storage inventory. The unit cost of the two-tank nitrate salt system is approximately $24/kWht, while the unit cost of the high pressure thermocline system is nominally 10 times as high. 3) For the supercritical fluids, the outer crown temperatures of the receiver tubes are in the range of 700 to 800 °C. At temperatures of 700 °C and above

  5. Conceptual design report: Nuclear materials storage facility renovation. Part 1, Design concept. Part 2, Project management

    SciTech Connect

    1995-07-14

    The Nuclear Materials Storage Facility (NMSF) at the Los Alamos National Laboratory (LANL) was a Fiscal Year (FY) 1984 line-item project completed in 1987 that has never been operated because of major design and construction deficiencies. This renovation project, which will correct those deficiencies and allow operation of the facility, is proposed as an FY 97 line item. The mission of the project is to provide centralized intermediate and long-term storage of special nuclear materials (SNM) associated with defined LANL programmatic missions and to establish a centralized SNM shipping and receiving location for Technical Area (TA)-55 at LANL. Based on current projections, existing storage space for SNM at other locations at LANL will be loaded to capacity by approximately 2002. This will adversely affect LANUs ability to meet its mission requirements in the future. The affected missions include LANL`s weapons research, development, and testing (WRD&T) program; special materials recovery; stockpile survelliance/evaluation; advanced fuels and heat sources development and production; and safe, secure storage of existing nuclear materials inventories. The problem is further exacerbated by LANL`s inability to ship any materials offsite because of the lack of receiver sites for mate rial and regulatory issues. Correction of the current deficiencies and enhancement of the facility will provide centralized storage close to a nuclear materials processing facility. The project will enable long-term, cost-effective storage in a secure environment with reduced radiation exposure to workers, and eliminate potential exposures to the public. This document provides Part I - Design Concept which describes the selected solution, and Part II - Project Management which describes the management system organization, the elements that make up the system, and the control and reporting system.

  6. Electrochemical and mechanical processes at surfaces and interfaces of advanced materials for energy storage

    NASA Astrophysics Data System (ADS)

    Shi, Feifei

    Energy storage is a rapidly emerging field. In almost all energy storage applications, surfaces and interfaces are playing dominant roles. Examples are fuel cell electrodes, where electro-catalytic reactions occur, Li-ion battery (LIB) electrodes, where electrolyte decomposition and passivation commence simultaneously, and failure (fracture) of battery electrodes, where surface crack initiation greatly affects battery endurance. The most fundamental chemical, electrochemical, and mechanical problems in energy storage applications originate from surfaces and interfaces. This thesis investigates the electrochemical and mechanical processes at surfaces and interfaces of advanced materials for energy applications. The thesis includes the following five main research topics. (Abstract shortened by ProQuest.).

  7. Advanced Devices for Cryogenic Thermal Management

    NASA Astrophysics Data System (ADS)

    Bugby, D.; Stouffer, C.; Garzon, J.; Beres, M.; Gilchrist, A.

    2006-04-01

    This paper describes six advanced cryogenic thermal management devices/subsystems developed by Swales Aerospace for ground/space-based applications of interest to NASA, DoD, and the commercial sector. The devices/subsystems described herein include the following: (a) a differential thermal expansion cryogenic thermal switch (DTE-CTSW) constructed with high purity aluminum end-pieces and an Ultem support rod for the 6 K Mid-Infrared Instrument (MIRI) on the James Webb Space Telescope (JWST) (b) a quad-redundant DTE-CTSW assembly for the 35 K science instruments (NIRCam, NIRSpec, and FGS) mounted on the JWST Integrated Science Instrument Module (ISIM) (c) a cryogenic diode heat pipe (CDHP) thermal switching system using methane as the working fluid for the 100 K CRISM hyperspectral mapping instrument on the Mars Reconnaissance Orbiter (MRO) and (d) three additional devices/subsystems developed during the AFRL-sponsored CRYOTOOL program, which include a dual DTE-CTSW/dual cryocooler test bed, a miniaturized neon cryogenic loop heat pipe (mini-CLHP), and an across gimbal cryogenic thermal transport system (GCTTS). For the first three devices/subsystems mentioned above, this paper describes key aspects of the development efforts including concept definition, design, fabrication, and testing. For the latter three, this paper provides brief overview descriptions as key details are provided in a related paper.

  8. Natural language processing and advanced information management

    NASA Technical Reports Server (NTRS)

    Hoard, James E.

    1989-01-01

    Integrating diverse information sources and application software in a principled and general manner will require a very capable advanced information management (AIM) system. In particular, such a system will need a comprehensive addressing scheme to locate the material in its docuverse. It will also need a natural language processing (NLP) system of great sophistication. It seems that the NLP system must serve three functions. First, it provides an natural language interface (NLI) for the users. Second, it serves as the core component that understands and makes use of the real-world interpretations (RWIs) contained in the docuverse. Third, it enables the reasoning specialists (RSs) to arrive at conclusions that can be transformed into procedures that will satisfy the users' requests. The best candidate for an intelligent agent that can satisfactorily make use of RSs and transform documents (TDs) appears to be an object oriented data base (OODB). OODBs have, apparently, an inherent capacity to use the large numbers of RSs and TDs that will be required by an AIM system and an inherent capacity to use them in an effective way.

  9. Advances in the management of thyroid cancer.

    PubMed

    Shaha, Ashok R

    2005-01-01

    The incidence of thyroid cancer is rapidly increasing in the United States. A large number of incidentalomas are found during routine head and neck evaluations. The diagnostic workup still revolves around fine needle aspiration biopsy. Ultrasound guided fine needle aspiration biopsy is likely to yield the best results. Surgical resection offers the best treatment choice. Controversy continues in relation to total versus less than total thyroidectomy. The incidence of complications is inversely proportional to the extent of surgery and obviously related to the experience of the operating surgeon. The decision regarding the extent of thyroidectomy should be based on prognostic factors and risk groups. Prognostic factors are well defined, such as age, grade of the tumor, extrathyroidal extension, size, distant metastasis, and histology. Nodal metastasis has minimal implications. Based on prognostic factors, thyroid cancer can be divided into low, intermediate and high risk groups. In the high risk group and in selected intermediate risk patients, radioactive iodine dosimetry and ablation should be considered after total thyroidectomy. PET scanning and the use of recombinant TSH have been major advances in follow-up care for patients with thyroid cancer. Thyroglobulin appears to be a very good tumor marker for follow-up. No major breakthrough is noted in the management of anaplastic thyroid cancer, however, identification of RET mutation has been extremely helpful in evaluating the family members of the patient with medullary thyroid cancer with strong consideration given to total thyroidectomy. PMID:17462286

  10. Advanced multilayer optical data storage: origins and future prospect

    NASA Astrophysics Data System (ADS)

    Esener, Sadik

    2008-02-01

    Fifty years have elapsed since the first concepts in volumetric memories have been put forward. Nowadays, the perceived need for low cost removable TB/disk storage systems is one more time fueling the development of 3D media, recording and readout systems. This paper, by reviewing some of the key historic moments and accomplishments in the development of volumetric recording systems attempts to shine light on possible future developments and directions while paying a tribute to many of the researchers that have contributed to the development of this field: in particular to Dr. Hans J. Coufal who for many years has provided vision, guidance, and leadership by leading recent INSIC Technology Roadmap efforts and organizing this conference. He is and will be greatly missed at a time when our common dreams may become a commercial reality.

  11. Nanostructured Materials for Advanced Electrochemical Energy Storage Applications

    NASA Astrophysics Data System (ADS)

    Wilson, Benjamin E.

    This dissertation discusses work aimed at developing and improving nanostructured materials for electrochemical energy storage, specifically electrochemical double layer capacitors (EDLCs) and lithium-ion batteries (LIBs). This was achieved through a combination of templating, precursor selection, and heteroatom doping to control the morphology and composition of the materials for improved performance in both types of energy storage. The first part of the thesis discusses EDLCs. First, a new method to produce soft-templated carbon materials is described. This process allows for improved production of mesoporous carbon made through soft templating. The work continues with using ionic liquids to dope nitrogen into hard templated mesoporous carbon. This led to a 40% improvement in specific capacitance due to improved conductivity. The section concludes with an investigation of physical and electrochemical properties of twelve ionic liquid electrolytes to determine which parameters are most important to achieve a high energy density. The second part discusses my work on LIBs, starting with a design of a low-cost electrochemical cell for in-situ X-ray diffraction monitoring during galvanostatic cycling. It continues with the development of a novel cathode material, Li8ZrO6, with a high lithium content. In this material, the redox activity is localized on oxygen atoms. Li8ZrO6 displays initial capacities higher than those of commercial materials but has large polarization. The capacity is further improved with transition metal doping, leading to a final specific capacity of over 175 mAh/g after 140 cycles at a rate of C/5.

  12. Automated File Transfer and Storage Management Concepts for Space

    NASA Technical Reports Server (NTRS)

    Hogie, Keith; Criscuolo, Ed; Parise, Ron

    2004-01-01

    This presentation will summarize work that has been done to prototype and analyze approaches for automated file transfer and storage management for space missions. The concepts were prototyped in an environment with data files being generated at the target mission rates and stored in onboard files. The space-to-ground link was implemented using a channel simulator to introduce representative mission delays and errors. The system was operated for days with data files building up on the spacecraft and periodically being transferred to ground storage during a limited contact time. Overall performance was measured to identify limits under which the entire data volume could be transferred automatically while still fitting into the mission s limited contact time. The overall concepts, measurements, and results will be presented.

  13. The intelligent user interface for NASA's advanced information management systems

    NASA Technical Reports Server (NTRS)

    Campbell, William J.; Short, Nicholas, Jr.; Rolofs, Larry H.; Wattawa, Scott L.

    1987-01-01

    NASA has initiated the Intelligent Data Management Project to design and develop advanced information management systems. The project's primary goal is to formulate, design and develop advanced information systems that are capable of supporting the agency's future space research and operational information management needs. The first effort of the project was the development of a prototype Intelligent User Interface to an operational scientific database, using expert systems and natural language processing technologies. An overview of Intelligent User Interface formulation and development is given.

  14. Advanced Hybrid Particulate Collector Project Management Plan

    SciTech Connect

    Miller, S.J.

    1995-11-01

    As the consumption of energy increases, its impact on ambient air quality has become a significant concern. Recent studies indicate that fine particles from coal combustion cause health problems as well as atmospheric visibility impairment. These problems are further compounded by the concentration of hazardous trace elements such as mercury, cadmium, selenium, and arsenic in fine particles. Therefore, a current need exists to develop superior, but economical, methods to control emissions of fine particles. Since most of the toxic metals present in coal will be in particulate form, a high level of fine- particle collection appears to be the best method of overall air toxics control. However, over 50% of mercury and a portion of selenium emissions are in vapor form and cannot be collected in particulate control devices. Therefore, this project will focus on developing technology not only to provide ultrahigh collection efficiency of particulate air toxic emissions, but also to capture vapor- phase trace metals such as mercury and selenium. Currently, the primary state-of-the-art technologies for particulate control are fabric filters (baghouses) and electrostatic precipitators (ESPs). However, they both have limitations that prevent them from achieving ultrahigh collection of fine particulate matter and vapor-phase trace metals. The objective of this project is to develop a highly reliable advanced hybrid particulate collector (AHPC) that can provide > 99.99 % particulate collection efficiency for all particle sizes between 0.01 and 50 14m, is applicable for use with all U.S. coals, and is cost-0443competitive with existing technologies. Phase I of the project is organized into three tasks: Task I - Project Management, Reporting, and Subcontract Consulting Task 2 - Modeling, Design, and Construction of 200-acfm AHPC Model Task 3 - Experimental Testing and Subcontract Consulting

  15. Advanced nanostructured materials for energy storage and conversion

    NASA Astrophysics Data System (ADS)

    Hutchings, Gregory S.

    Due to a global effort to reduce greenhouse gas emissions and to utilize renewable sources of energy, much effort has been directed towards creating new alternatives to fossil fuels. Identifying novel materials for energy storage and conversion can enable radical changes to the current fuel production infrastructure and energy utilization. The use of engineered nanostructured materials in these systems unlocks unique catalytic activity in practical configurations. In this work, research efforts have been focused on the development of nanostructured materials to address the need for both better energy conversion and storage, with applications toward Li-O2 battery electrocatalysts, electrocatalytic generation of H2, conversion of furfural to useful chemicals and fuels, and Li battery anode materials. Highly-active alpha-MnO2 materials were synthesized for use as bifunctional oxygen reduction (ORR) and evolution (OER) catalysts in Li-O2 batteries, and were evaluated under operating conditions with a novel in situ X-ray absorption spectroscopy configuration. Through detailed analysis of local coordination and oxidation states of Mn atoms at key points in the electrochemical cycle, a self-switching behavior affecting the bifunctional activity was identified and found to be critical. In an additional study of materials for lithium batteries, nanostructured TiO2 anode materials doped with first-row transition metals were synthesized and evaluated for improving battery discharge capacity and rate performance, with Ni and Co doping at low levels found to cause the greatest enhancement. In addition to battery technology research, I have also sought to find inexpensive and earth-abundant electrocatalysts to replace state-of-the-art Pt/C in the hydrogen evolution reaction (HER), a systematic computational study of Cu-based bimetallic electrocatalysts was performed. During the screening of dilute surface alloys of Cu mixed with other first-row transition metals, materials with

  16. Managing variability in the IO performance of petascale storage systems.

    SciTech Connect

    Wolf, Matthew; Zheng, Fang; Klasky, Scott; Schwan, Karsten; Oldfield, Ron A.; Lofstead, Gerald Fredrick, II; Liu, Qing; Kordenbrock, Todd

    2010-11-01

    Significant challenges exist for achieving peak or even consistent levels of performance when using IO systems at scale. They stem from sharing IO system resources across the processes of single large-scale applications and/or multiple simultaneous programs causing internal and external interference, which in turn, causes substantial reductions in IO performance. This paper presents interference effects measurements for two different file systems at multiple supercomputing sites. These measurements motivate developing a 'managed' IO approach using adaptive algorithms varying the IO system workload based on current levels and use areas. An implementation of these methods deployed for the shared, general scratch storage system on Oak Ridge National Laboratory machines achieves higher overall performance and less variability in both a typical usage environment and with artificially introduced levels of 'noise'. The latter serving to clearly delineate and illustrate potential problems arising from shared system usage and the advantages derived from actively managing it.

  17. Advancing Project Management in Learning Organizations

    ERIC Educational Resources Information Center

    Bourne, Lynda; Walker, Derek H. T.

    2004-01-01

    Effective project managers are required to have both "hard" technical skills to help control the iron triangle of time, cost and functional scope as well as relationship management skills to work effectively with people and get the best out of them. This paper argues that project managers also need a third skill: we refer to it as tapping into the…

  18. Advanced Mirror System Demonstrator (AMSD) Risk Management

    NASA Technical Reports Server (NTRS)

    Byberg, Alicia; Russell, J. Kevin; Kaukler, Donna; Burdine, Robert V. (Technical Monitor)

    2002-01-01

    This paper will report risk issues associated with designing, manufacturing, and testing the Advanced Mirror System Demonstrator (AMSD). The Advanced Mirror System Demonstrator (AMSD) will be developed as a lightweight primary mirror system that can be produced at a low cost and with a short manufacturing schedule. This technology will add to the knowledge base for selection for the Next Generation Space Telescope (NGST), Space Based Laser (SBL), Research Laboratory mission (AFRL), and other government agency programs.

  19. Polymer/Graphene Hybrids for Advanced Energy-Conversion and -Storage Materials.

    PubMed

    Cui, Linfan; Gao, Jian; Xu, Tong; Zhao, Yang; Qu, Liangti

    2016-04-20

    Polymer/graphene-based materials with interesting physical and chemical properties have been attracting considerable attention and have been shown to have great potential as active materials in the field of energy conversion and storage. In this review, we focus on recent significant advances in the fabrication and application of polymer/graphene hybrids as electrocatalysts and electrode materials. Synthetic strategies and application of these materials in energy conversion and storage are presented, particularly in devices such as fuel cells, actuators, and supercapacitors, accompanied with a discussion of the challenges and research directions necessary for the future development of polymer/graphene hybrids. PMID:26878997

  20. Epidemiology and Challenges to the Management of Advanced CKD.

    PubMed

    Hazzan, Azzour D; Halinski, Candice; Agoritsas, Sofia; Fishbane, Steven; DeVita, Maria V

    2016-07-01

    Advanced CKD is a period of CKD that differs greatly from earlier stages of CKD in terms of treatment goals. Treatment during this period presents particular challenges as further loss of kidney function heralds the need for renal replacement therapy. Successful management during this period increases the likelihood of improved transitions to ESRD. However, there are substantial barriers to optimal advanced CKD care. In this review, we will discuss advanced CKD definitions and epidemiology and outcomes. PMID:27324673

  1. Advanced practice roles in the managed care environment.

    PubMed

    Madden, M J; Ponte, P R

    1994-01-01

    The role of the advanced practice nurse is based on expert clinical knowledge and skill and is practiced in multiple settings. As healthcare reform emerges, the context in which healthcare is delivered changes. The authors describe a creative approach to packaging and marketing the services of advanced practice nurses to the customers of the managed care system. PMID:8308561

  2. Barriers to Professional Advancement among Female Managers.

    ERIC Educational Resources Information Center

    O'Leary, Virginia E.

    It appears that there is nothing inherently associated with femaleness which should preclude the ascendence of women into management positions. However, barriers do exist and they stem from such factors as societal sex-role stereotypes, attitudes toward women in management, attitudes toward female competence, and the prevalence of the male…

  3. Advances in Serials Management. Volume 6.

    ERIC Educational Resources Information Center

    Hepfer, Cindy, Ed.; Gammon, Julia, Ed.; Malinowski, Teresa, Ed.

    In order to further discussion and support constructive change, this volume presents the following eight papers on various dimensions of serials management: (1) "CD-ROMs, Surveys, and Sales: The OSA [Optical Society of America] Experience" (Frank E. Harris and Alan Tourtlotte); (2) "Management and Integration of Electronic Journals into the…

  4. Advanced Interval Management (IM) Concepts of Operations

    NASA Technical Reports Server (NTRS)

    Barmore, Bryan E.; Ahmad, Nash'at N.; Underwood, Matthew C.

    2014-01-01

    This document provides a high-level description of several advanced IM operations that NASA is considering for future research and development. It covers two versions of IM-CSPO and IM with Wake Mitigation. These are preliminary descriptions to support an initial benefits analysis

  5. Individualized management of advanced bladder cancer: Where do we stand?

    PubMed

    Burgess, Earle F

    2015-04-01

    Despite recent progress in the development of novel targeted therapies in various malignancies, the management of advanced urothelial cancer has changed little over the past 2 decades. Comorbidities inherent to patients with bladder cancer often preclude the use of standard cisplatin-based chemotherapy and underscore the need for individualized treatment recommendations and the development of more effective therapies. This review discusses current issues relevant to the management of patients with locally advanced and metastatic urothelial carcinoma of the bladder and highlights recent advances in defining molecular aberrations that may ultimately lead to personalized therapeutic decision making. PMID:24332641

  6. ADVANCES IN INTEGRATING INSECT GROWTH REGULATORS INTO STORAGE PEST MANAGEMENT

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Insect growth regulators (IGRs) are insecticides that mimic insect-produced hormones that regulate the developmental process. They generally have little or no mammalian toxicity, and are considered reduced-risk insecticides that are often exempt from tolerance requirements of regulatory agencies. Al...

  7. The diabetic foot management - recent advance.

    PubMed

    Sinwar, Prabhu Dayal

    2015-03-01

    Diabetic ulceration of the foot represents a major global medical, social and economic problem. It is the commonest major end-point of diabetic complications. Diabetic neuropathy and peripheral vascular disease are the main etiological factors in foot ulceration and may act alone, together, or in combination with other factors such as microvascular disease, biomechanical abnormalities, limited joint mobility and increased susceptibility to infection. In the diabetic foot, distal sensory polyneuropathy is seen most commonly. The advent of insulin overcame the acute problems of ketoacidosis and infection, but could not prevent the vascular and neurological complications. Management of diabetic neuropathic ulcer by appropriate and timely removal of callus, control of infection and reduction of weight bearing forces. Management of diabetic ischaemic foot are medical management, surgical management and percutaneous transluminal angioplasty of stenosed and occluded lower extremity arteries. Foot ulceration in persons with diabetes is the most frequent precursor to amputation. PMID:25638739

  8. Management of dysphagia in advanced oropharyngeal cancer.

    PubMed

    Penner, Jamie L; McClement, Susan E; Sawatzky, Jo-Ann V

    2007-05-01

    Individuals with advanced oropharyngeal cancer often experience dysphagia as a result of their illness and its treatment. Research consistently demonstrates that dysphagia and difficulty with oral intake have many implications, including a negative impact on quality of life. Nurses are in a key position to provide support and initiate appropriate interventions for individuals with dysphagia. Using the Human Response to Illness model (Mitchell et al, 1991) as an organising framework, this paper presents a critical review of the empirical literature regarding dysphagia in individuals with advanced oropharyngeal cancer that will: i) provide the reader with a comprehensive understanding of dysphagia; ii) identify current gaps in our knowledge; and iii) establish the foundation for appropriate evidence-based interventions to optimise functioning and quality of life in this patient population. PMID:17577172

  9. Advanced Fuel Cell System Thermal Management for NASA Exploration Missions

    NASA Technical Reports Server (NTRS)

    Burke, Kenneth A.

    2009-01-01

    The NASA Glenn Research Center is developing advanced passive thermal management technology to reduce the mass and improve the reliability of space fuel cell systems for the NASA exploration program. An analysis of a state-of-the-art fuel cell cooling systems was done to benchmark the portion of a fuel cell system s mass that is dedicated to thermal management. Additional analysis was done to determine the key performance targets of the advanced passive thermal management technology that would substantially reduce fuel cell system mass.

  10. Pancreatic Pseudocysts: Advances in Endoscopic Management.

    PubMed

    Ge, Phillip S; Weizmann, Mikhayla; Watson, Rabindra R

    2016-03-01

    Endoscopic drainage is the first-line therapy in the management of pancreatic pseudocysts. Before endoscopic drainage, clinicians should exclude the presence of pancreatic cystic neoplasms and avoid drainage of immature peripancreatic fluid collections or pseudoaneurysms. The indication for endoscopic drainage is not dependent on absolute cyst size alone, but on the presence of attributable signs or symptoms. Endoscopic management should be performed as part of a multidisciplinary approach in close cooperation with surgeons and interventional radiologists. Drainage may be performed either via a transpapillary approach or a transmural approach; additionally, endoscopic necrosectomy may be performed for patients with walled-off necrosis. PMID:26895678

  11. Advances in the management of macular degeneration

    PubMed Central

    2014-01-01

    Current management of age-related macular degeneration (AMD) can be divided into two categories: first, anti-vasoendothelial growth factor (anti-VEGF) injection for wet macular degeneration; second, anti-oxidant vitamins for dry macular degeneration. New therapies are being developed for both of these diseases using novel technologies and different modes of administration. The hope is that some of these therapies will achieve significant improvement to current management and prevent future loss of vision in this devastating eye condition. PMID:24860651

  12. Synthesis and characterization of inorganic nanostructured materials for advanced energy storage

    NASA Astrophysics Data System (ADS)

    Xie, Jin

    The performance of advanced energy storage devices is intimately connected to the designs of electrodes. To enable significant developments in this research field, we need detailed information and knowledge about how the functions and performances of the electrodes depend on their chemical compositions, dimensions, morphologies, and surface properties. This thesis presents my successes in synthesizing and characterizing electrode materials for advanced electrochemical energy storage devices, with much attention given to understanding the operation and fading mechanism of battery electrodes, as well as methods to improve their performances and stabilities. This dissertation is presented within the framework of two energy storage technologies: lithium ion batteries and lithium oxygen batteries. The energy density of lithium ion batteries is determined by the density of electrode materials and their lithium storage capabilities. To improve the overall energy densities of lithium ion batteries, silicon has been proposed to replace lithium intercalation compounds in the battery anodes. However, with a ~400% volume expansion upon fully lithiation, silicon-based anodes face serious capacity degradation in battery operation. To overcome this challenge, heteronanostructure-based Si/TiSi2 were designed and synthesized as anode materials for lithium ion batteries with long cycling life. The performance and morphology relationship was also carefully studied through comparing one-dimensional and two-dimensional heteronanostructure-based silicon anodes. Lithium oxygen batteries, on the other hand, are devices based on lithium conversion chemistries and they offer higher energy densities compared to lithium ion batteries. However, existing carbon based electrodes in lithium oxygen batteries only allow for battery operation with limited capacity, poor stability and low round-trip efficiency. The degradation of electrolytes and carbon electrodes have been found to both contribute

  13. Organic nitrogen storage in mineral soil: Implications for policy and management.

    PubMed

    Bingham, Andrew H; Cotrufo, M Francesca

    2016-05-01

    Nitrogen is one of the most important ecosystem nutrients and often its availability limits net primary production as well as stabilization of soil organic matter. The long-term storage of nitrogen-containing organic matter in soils was classically attributed to chemical complexity of plant and microbial residues that retarded microbial degradation. Recent advances have revised this framework, with the understanding that persistent soil organic matter consists largely of chemically labile, microbially processed organic compounds. Chemical bonding to minerals and physical protection in aggregates are more important to long-term (i.e., centuries to millennia) preservation of these organic compounds that contain the bulk of soil nitrogen rather than molecular complexity, with the exception of nitrogen in pyrogenic organic matter. This review examines for the first time the factors and mechanisms at each stage of movement into long-term storage that influence the sequestration of organic nitrogen in the mineral soil of natural temperate ecosystems. Because the factors which govern persistence are different under this newly accepted paradigm we examine the policy and management implications that are altered, such as critical load considerations, nitrogen saturation and mitigation consequences. Finally, it emphasizes how essential it is for this important but underappreciated pool to be better quantified and incorporated into policy and management decisions, especially given the lack of evidence for many soils having a finite capacity to sequester nitrogen. PMID:26874768

  14. Advances in understanding and managing bullous pemphigoid

    PubMed Central

    Zhao, Cathy Y.; Murrell, Dedee F.

    2015-01-01

    Bullous pemphigoid (BP) is the commonest subtype of autoimmune blistering disease in most countries of the world. It occurs most frequently in elderly patients and is characterised clinically by large, tense blisters in the skin preceded by urticarial plaques and pruritus. Immunopathologically, it is characterised by autoantibodies directed against the 180 kD antigen (BP180) and the 230 kD antigen (BP230). New knowledge regarding BP is being continually uncovered. This article reviews the recent advances in BP, including newer diagnostic tests, standardised outcome measures and emerging therapeutic options, as well as the evidence supporting their use. PMID:26918143

  15. Moomba Lower Daralingie Beds (LDB) gas storage project: Reservoir management using a novel numerical simulation technique

    SciTech Connect

    Jamal, F.G.

    1994-12-31

    Engineers managing underground gas storage projects are often faced with challenges involving gas migration, inventory variance, gas quality and inventory-pressures. This paper discusses a unique underground gas storage project where sales gas and ethane are stored in two different but communicating regions of the same reservoir. A commercially available reservoir simulator was used to model the fluid flow behavior in this reservoir, hence, providing a tool for better management and use of the existing gas storage facilities.

  16. Dietary management of Type I glycogen storage disease.

    PubMed

    Folk, C C; Greene, H L

    1984-03-01

    The most commonly recognized type of glycogen storage disease (von Gierke's disease) results from deficient glucose-6-phosphatase activity. This enzyme is the last step in the release of free glucose from the liver into the circulation. Thus, the most prominent and life-threatening complication in the illness is severe and often prolonged hypoglycemia, which occurs after the dietary glucose is normally removed from the circulation. With an optimal dietary intake spaced at 2 1/2- to 3 1/2-hour intervals, the blood glucose can be maintained in the normal range during the daytime, but hypoglycemia may occur during overnight fasting. Recent advances in the understanding of the pathophysiology of the illness have led to the use of frequent high-starch feedings during the day and nocturnal intragastric infusions of liquid formulas containing glucose polymers. The liquid formula is infused through either a nasogastric or a gastrostomy tube continuously at night while the patient sleeps. The success of this treatment not only has improved the survival rate but also has corrected the abnormal blood chemistries and generated a more normal rate of growth and development. Because patients with this disease are reaching adulthood in greater numbers, it is necessary for dietitians caring for adults as well as for children to become familiar with the prescribed methods of treatment. PMID:6583274

  17. Legal and records management issue of Optical Disk Storage media

    SciTech Connect

    Nusbaum, A.

    1991-01-01

    The advent of optical storage has made the digital storage of documents a viable option from both a practical and legal perspective. However, the availability of Optical Disk Storage raises questions regarding the destruction of the stored records and standards of longevity, and the admissibility in court of records produced from optical storage has not been tested. This paper will attempt to address these issues. 6 refs.

  18. Advances in the Endoscopic Management of Obesity

    PubMed Central

    Behary, Jason; Kumbhari, Vivek

    2015-01-01

    Obesity has become a worldwide epidemic with significant impact on quality of life, morbidity, and mortality rates. Over the past two decades, bariatric surgery has established itself as the most effective and durable treatment for patients with obesity and its associated comorbidities. However, despite the use of minimally invasive techniques, bariatric surgery is associated with complications in approximately 15% of patients, has a substantial cost, and is used by only 1% of patients who are eligible. Therefore, there is a need for effective minimally invasive therapies, which will be utilized by the large proportion of obese patients who are in desperate need of treatment but are not receiving any. Endoscopic approaches to the management of obesity have been developed, with the aim of delivering more effective, durable, and safer methods of weight reduction. In this paper, we review currently available and future endoscopic therapies that will likely join the armamentarium used in the management of obesity. PMID:26106413

  19. Business Management in the advanced information society

    NASA Astrophysics Data System (ADS)

    Saeki, Akio

    This is a record of the commemorative lecture at the fifth anniversary of the establishment of the JICST Tohoku Branch Office. Lecturer explains about business management in the information age. "Management" originally means sensing and coping with changes. Thus, the business has to get information as quickly as possible and take the best possible measure for the new issues. As it is definitely important for the business to make an appropriate prediction, information including unknown facts is very valuable. Technological prediction is particulary indispensable for the business. It is available, to some extent, by looking back the steps of technological development in the past. As the characteristics of information age, lecturer explains that there will be less information gap in the world, due to the development of telecommunication technology.

  20. System and method for advanced power management

    DOEpatents

    Atcitty, Stanley; Symons, Philip C.; Butler, Paul C.; Corey, Garth P.

    2009-07-28

    A power management system is provided that includes a power supply means comprising a plurality of power supply strings, a testing means operably connected to said plurality of power supply strings for evaluating performance characteristics of said plurality of power supply strings, and a control means for monitoring power requirements and comprising a switching means for controlling switching of said plurality of power supply strings to said testing means.

  1. Management of advanced hair loss patterns.

    PubMed

    Beehner, Michael L

    2013-08-01

    This article covers how to manage patients with extensive hair loss in whom complete, dense coverage is not possible. In addition to discussing planning a transplant pattern for already bald men, I discuss a conservative approach for recognizing and transplanting younger patients who have telltale warning signs that may evolve to extensive hair loss. For both groups, a variant of a frontal forelock-type pattern is usually the best course to follow. PMID:24017980

  2. Recent advances in management of genital herpes.

    PubMed Central

    Tétrault, I.; Boivin, G.

    2000-01-01

    OBJECTIVE: To provide an update on new diagnostic tests and antiviral strategies for managing genital herpes. QUALITY OF EVIDENCE: Treatment guidelines are based on randomized clinical trials and recommendations from the Expert Working Group on Canadian Guidelines for Sexually Transmitted Diseases. Recommendations concerning other aspects of managing genital herpes (e.g., indications for using type-specific serologic tests) are mainly based on expert opinion. MAIN MESSAGE: Genital herpes is one of the most common sexually transmitted diseases, affecting about 20% of sexually active people; up to 80% of cases are undiagnosed. Because of frequent atypical presentation and the emotional burden associated with genital herpes, clinical diagnosis should be confirmed by viral culture. Type-specific serologic assays are now available, but their use is often restricted to special situations and requires adequate counseling. New antivirals (valacyclovir and famciclovir) with improved pharmacokinetic profiles have now been approved for episodic treatment of recurrences and suppressive therapy. CONCLUSION: Wise use of new diagnostic assays for herpes simplex coupled with more convenient treatment regimens should provide better management of patients with genital herpes. Images Figure 1 PMID:10955181

  3. Advances in the management of chronic insomnia.

    PubMed

    Kay-Stacey, Margaret; Attarian, Hrayr

    2016-01-01

    Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these treatments. However, in recent years, alternative ways of providing these behavioral therapies that make them more widely available have been investigated. Drugs also play an important role in the treatment of insomnia and new drugs have been introduced as options for treating patients with sleep initiation and sleep maintenance insomnia. In this review, we will discuss advances in the past six years in both non-pharmacologic and pharmacologic treatments for patients with chronic insomnia. We will also review the controversies surrounding some of the current drug treatments, as well as the role that technology and personal activity monitoring devices may play in treating insomnia. PMID:27383400

  4. Recent Advances in Postoperative Pain Management

    PubMed Central

    Vadivelu, Nalini; Mitra, Sukanya; Narayan, Deepak

    2010-01-01

    Good pain control after surgery is important to prevent negative outcomes such as tachycardia, hypertension, myocardial ischemia, decrease in alveolar ventilation, and poor wound healing. Exacerbations of acute pain can lead to neural sensitization and release of mediators both peripherally and centrally. Clinical wind up occurs from the processes of N-Methyl D-Aspartate (NMDA) activation, wind up central sensitization, long-term potentiation of pain (LTP), and transcription-dependent sensitization. Advances in the knowledge of molecular mechanisms have led to the development of multimodal analgesia and new pharmaceutical products to treat postoperative pain. The new pharmacological products to treat postoperative pain include extended-release epidural morphine and analgesic adjuvants such as capsaicin, ketamine, gabapentin, pregabalin dexmetomidine, and tapentadol. Newer postoperative patient-controlled analgesia (PCA) in modes such as intranasal, regional, transdermal, and pulmonary presents another interesting avenue of development. PMID:20351978

  5. Recent advances in understanding and managing cholestasis

    PubMed Central

    Wagner, Martin; Trauner, Michael

    2016-01-01

    Cholestatic liver diseases are hereditary or acquired disorders with impaired hepatic excretion and enterohepatic circulation of bile acids and other cholephiles. The distinct pathological mechanisms, particularly for the acquired forms of cholestasis, are not fully revealed, but advances in the understanding of the molecular mechanisms and identification of key regulatory mechanisms of the enterohepatic circulation of bile acids have unraveled common and central mechanisms, which can be pharmacologically targeted. This overview focuses on the central roles of farnesoid X receptor, fibroblast growth factor 19, and apical sodium-dependent bile acid transporter for the enterohepatic circulation of bile acids and their potential as new drug targets for the treatment of cholestatic liver disease. PMID:27134744

  6. Recent advances in management of bladder overactivity

    PubMed Central

    Wein, Alan J

    2010-01-01

    Pharmacologic therapies, primarily antimuscarinic agents, have been the mainstay of treatment for overactive bladder. These drugs produce variable efficacy, a moderate rate of side effects, and rare occurrences of cure. The search for newer and better formulations and derivatives of this class of medication as well as novel therapies is ongoing and primarily fueled by the high prevalence of overactive bladder and the tremendous number of health care dollars spent on current therapy. Surgical options for overactive bladder have evolved slowly and are currently reserved for medical treatment failures and drug intolerance. This article will highlight the new drugs and therapies brought into clinical use for the treatment of overactive bladder over the last few years as well as a promising new agent in the advanced stages of development. PMID:20948824

  7. Enabling Renewable Energy and the Future Grid with Advanced Electricity Storage

    SciTech Connect

    Yang, Zhenguo; Liu, Jun; Baskaran, Suresh; Imhoff, Carl H.; Holladay, Jamelyn D.

    2010-08-06

    Environmental concerns about using fossil fuels and their resource constrains, along with that on energy security, have spurred great interests in generating electrical energy from renewable sources such as wind and solar. The variable and stochastic nature of renewable sources however makes solar and wind power difficult to manage, especially at high levels of penetration. To effectively use the intermittent renewable energy and enable its delivery demand electrical energy storage (EES) that can also improve the reliability, stability, and efficiency of the electrical grid, which is expected to support plug-in electrical vehicles; enable real-time, two-way communication to balance demand and supply. While EES has gained wide attention for hybrid and electrical vehicle (e.g. plug-in-hybrid electrical) needs, public awareness and understanding of the critical challenges in energy storage for renewable integration and the future grid is relatively lacking. This paper examines the benefits and challenges of EES, in particular electrochemical storage or battery technologies, and discusses the fundamental principles, economics, and feasibility of the storage technologies. It intends to provide an understanding of the needs and challenges of electrical storage technologies for the stationary applications and offer general directions of research and development to the materials community.

  8. Psoriasis: advances in pathophysiology and management

    PubMed Central

    MacDonald, A; Burden, A D

    2007-01-01

    Psoriasis is an inflammatory skin disease that affects 1–3% of Caucasian populations and may be persistent, disfiguring and stigmatising. There is a range of severity, but even when the affected body surface area is relatively limited the impact on day‐to‐day activities and social interactions may be significant. An understanding of the psychological burden and an appreciation that many patients are currently dissatisfied with their management has driven the development of more effective treatment. In recent years psoriasis has been the focus of intense investigation resulting in an improved understanding of the immunopathogenesis, and the development of new, targeted biological treatments. PMID:17989268

  9. Advances in the management of insomnia

    PubMed Central

    Bishop, Todd M.; Marcus, Jonathan A.

    2014-01-01

    Insomnia is highly prevalent and associated with considerable morbidity. Several very efficacious treatments, both pharmacologic and non-pharmacologic, exist for the management of insomnia. New modes of delivery and new formulations of existing sedative-hypnotic medications have been introduced. Novel agents are still being developed and tested to arrive at a hypnotic that has limited side effects while still being efficacious. Innovations with respect to behavioral interventions, which are drastically under-utilized, have focused mainly on making these interventions more widely available through dissemination efforts, briefer formats and more accessible platforms. PMID:24991425

  10. Capital cost estimates of selected advanced thermal energy storage technologies. Final report

    SciTech Connect

    Lawrence, W.T.

    1980-06-01

    A method for evaluating the first cost of diverse advances TES concepts on a common basis is presented. For a total sample of at least 20 baseline and advanced TES technologies, the methodology developed was to be applied in the calculation of actual cost and performance measures. Work on the development of TES has focused on 5 types of application areas: electric power generation, with solar input in which TES is used to store energy for use during cloudy periods or at night; conventional fuel-fired electric power generation, in which TES is used to improve load factors; cyclic losses, in which TES is used to reduce losses that occur when devices start and stop; batch losses, in which TES is used to recover waste heat; and source/sink mismatch, in which TES is used to increase the efficiency of processes that are dependent upon ambient temperatures. Chapter 2 defines reference operating characteristics; Chapter 2 gives the costing methodology; Chapter 4 describes the system; Chapter 5 describes the baseline systems; Chapter 6 analyzes the effect of input-storage-temperature requirements on solar-collector-hardware costs and the input-temperature requirements of off-peak electric-storage systems on compressor operating costs; and in Chapter 7, the effects of chemical heat pump COP and collector temperature on storage size and collector area are considered. (MCW)

  11. Knowledge Management Platform in Advanced Product Quality Planning

    NASA Astrophysics Data System (ADS)

    Chiliban, Bogdan; Baral, Lal Mohan; Kifor, Claudiu

    2014-12-01

    Knowledge is an essential part of organizational competitiveness. This vital resource must be managed correctly within organizations in order to achieve desired performance levels within all undertakings. The process of managing knowledge is a very difficult one due to the illusive nature of the resource itself. Knowledge is stored within every aspect of an organization starting from people and ending with documents and processes. The Knowledge Management Platform is designed as a facilitator for managers and employees in all endeavours knowledge related within the Advanced Product Quality Planning Procedure

  12. Management of nasolacrimal duct injuries in mid-facial advancement

    PubMed Central

    Balaji, S. M.

    2015-01-01

    Nasolacrimal duct (NLD) may be injured following trauma. During certain surgical procedure, inadvertent damage to the nasolacrimal apparatus may occur as well. Such instances should be immediately managed to prevent any subsequent complications. The management of such inadvertent injuries may be accomplished only with a thorough anatomic comprehension and surgical expertise in the field of operation. It also requires the presence of armamentarium required for its management in situations when complications arise. The case report discusses one such rare complication of NLD injury during Le Fort III osteotomy and advancement effectively managed by bicanalicular stenting. PMID:26389043

  13. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Donated Foods in Contracts With Food Service Management Companies § 250.52 Storage and inventory management of donated foods. (a) General requirements. The food service management company must meet the... and inventory with commercially purchased foods. The food service management company may store...

  14. High-temperature thermal storage systems for advanced solar receivers materials selections

    SciTech Connect

    Wilson, D.F.; DeVan, J.H.; Howell, M.

    1990-09-01

    Advanced space power systems that use solar energy and Brayton or Stirling heat engines require thermal energy storage (TES) systems to operate continuously through periods of shade. The receiver storage units, key elements in both Brayton and Stirling systems, are designed to use the latent heat of fusion of phase-change materials (PCMs). The power systems under current consideration for near-future National Aeronautics and Space Administration space missions require working fluid temperatures in the 1100 to 1400 K range. The PCMs under current investigation that gave liquidus temperatures within this range are the fluoride family of salts. However, these salts have low thermal conductivity, which causes large temperature gradients in the storage systems. Improvements can be obtained, however, with the use of thermal conductivity enhancements or metallic PCMs. In fact, if suitable containment materials can be found, the use of metallic PCMs would virtually eliminate the orbit associated temperature variations in TES systems. The high thermal conductivity and generally low volume change on melting of germanium and alloys based on silicon make them attractive for storage of thermal energy in space power systems. An approach to solving the containment problem, involving both chemical and physical compatibility, preparation of NiSi/NiSi{sub 2}, and initial results for containment of germanium and NiSi/NiSi{sub 2}, are presented. 7 refs., 10 figs., 4 tabs.

  15. High-temperature thermal storage systems for advanced solar receivers materials selections

    NASA Technical Reports Server (NTRS)

    Wilson, D. F.; Devan, J. H.; Howell, M.

    1990-01-01

    Advanced space power systems that use solar energy and Brayton or Stirling heat engines require thermal energy storage (TES) systems to operate continuously through periods of shade. The receiver storage units, key elements in both Brayton and Stirling systems, are designed to use the latent heat of fusion of phase-change materials (PCMs). The power systems under current consideration for near-future National Aeronautics and Space Administration space missions require working fluid temperatures in the 1100 to 1400 K range. The PCMs under current investigation that gave liquid temperatures within this range are the fluoride family of salts. However, these salts have low thermal conductivity, which causes large temperature gradients in the storage systems. Improvements can be obtained, however, with the use of thermal conductivity enhancements or metallic PCMs. In fact, if suitable containment materials can be found, the use of metallic PCMs would virtually eliminate the orbit associated temperature variations in TES systems. The high thermal conductivity and generally low volume change on melting of germanium and alloys based on silicon make them attractive for storage of thermal energy in space power systems. An approach to solving the containment problem, involving both chemical and physical compatibility, preparation of NiSi/NiSi2, and initial results for containment of germanium and NiSi/NiSi2, are presented.

  16. Autosomal dominant polycystic kidney disease: recent advances in clinical management

    PubMed Central

    Mao, Zhiguo; Chong, Jiehan; Ong, Albert C. M.

    2016-01-01

    The first clinical descriptions of autosomal dominant polycystic kidney disease (ADPKD) go back at least 500 years to the late 16 th century. Advances in understanding disease presentation and pathophysiology have mirrored the progress of clinical medicine in anatomy, pathology, physiology, cell biology, and genetics. The identification of PKD1 and PKD2, the major genes mutated in ADPKD, has stimulated major advances, which in turn have led to the first approved drug for this disorder and a fresh reassessment of patient management in the 21 st century. In this commentary, we consider how clinical management is likely to change in the coming decade. PMID:27594986

  17. Autosomal dominant polycystic kidney disease: recent advances in clinical management.

    PubMed

    Mao, Zhiguo; Chong, Jiehan; Ong, Albert C M

    2016-01-01

    The first clinical descriptions of autosomal dominant polycystic kidney disease (ADPKD) go back at least 500 years to the late 16 (th) century. Advances in understanding disease presentation and pathophysiology have mirrored the progress of clinical medicine in anatomy, pathology, physiology, cell biology, and genetics. The identification of PKD1 and PKD2, the major genes mutated in ADPKD, has stimulated major advances, which in turn have led to the first approved drug for this disorder and a fresh reassessment of patient management in the 21 (st) century. In this commentary, we consider how clinical management is likely to change in the coming decade. PMID:27594986

  18. Investigation and management of the hepatic glycogen storage diseases.

    PubMed

    Bhattacharya, Kaustuv

    2015-07-01

    The glycogen storage diseases (GSD) comprise a group of disorders that involve the disruption of metabolism of glycogen. Glycogen is stored in various organs including skeletal muscle, the kidneys and liver. The liver stores glycogen to supply the rest of the body with glucose when required. Therefore, disruption of this process can lead to hypoglycaemia. If glycogen is not broken down effectively, this can lead to hepatomegaly. Glycogen synthase deficiency leads to impaired glycogen synthesis and consequently the liver is small. Glycogen brancher deficiency can lead to abnormal glycogen being stored in the liver leading to a quite different disorder of progressive liver dysfunction. Understanding the physiology of GSD I, III, VI and IX guides dietary treatments and the provision of appropriate amounts and types of carbohydrates. There has been recent re-emergence in the literature of the use of ketones in therapy, either in the form of the salt D,L-3-hydroxybutyrate or medium chain triglyceride (MCT). High protein diets have also been advocated. Alternative waxy maize based starches seem to show promising early data of efficacy. There are many complications of each of these disorders and they need to be prospectively surveyed and managed. Liver and kidney transplantation is still indicated in severe refractory disease. PMID:26835382

  19. Investigation and management of the hepatic glycogen storage diseases

    PubMed Central

    2015-01-01

    The glycogen storage diseases (GSD) comprise a group of disorders that involve the disruption of metabolism of glycogen. Glycogen is stored in various organs including skeletal muscle, the kidneys and liver. The liver stores glycogen to supply the rest of the body with glucose when required. Therefore, disruption of this process can lead to hypoglycaemia. If glycogen is not broken down effectively, this can lead to hepatomegaly. Glycogen synthase deficiency leads to impaired glycogen synthesis and consequently the liver is small. Glycogen brancher deficiency can lead to abnormal glycogen being stored in the liver leading to a quite different disorder of progressive liver dysfunction. Understanding the physiology of GSD I, III, VI and IX guides dietary treatments and the provision of appropriate amounts and types of carbohydrates. There has been recent re-emergence in the literature of the use of ketones in therapy, either in the form of the salt D,L-3-hydroxybutyrate or medium chain triglyceride (MCT). High protein diets have also been advocated. Alternative waxy maize based starches seem to show promising early data of efficacy. There are many complications of each of these disorders and they need to be prospectively surveyed and managed. Liver and kidney transplantation is still indicated in severe refractory disease. PMID:26835382

  20. Emergency management of ureteral stones: Recent advances

    PubMed Central

    Osorio, Luis; Lima, Estêvão; Autorino, Riccardo; Marcelo, Filinto

    2008-01-01

    Most ureteral stones can be observed with reasonable expectation of uneventful stone passage. When an active ureteral stone treatment is warranted, the best procedure to choose is dependent on several factors, besides stone size and location, including operators’ experience, patients’ preference, available equipment and related costs. Placement of double-J stent or nephrostomy tube represents the classical procedures performed in a renal colic due to acute ureteral obstruction when the conservative drug therapy does not resolve the symptoms. These maneuvers are usually followed by ureteroscopy or extracorporeal shockwave lithotripsy, which currently represent the mainstay of treatment for ureteral stones. In this review paper a literature search was performed to identify reports dealing with emergency management of renal colic due to ureteral stones. The main aspects related to this debated issue are analyzed and the advantages and disadvantages of each treatment option are carefully discussed. PMID:19468497

  1. Storage Information Management System (SIMS) Spaceflight Hardware Warehousing at Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Kubicko, Richard M.; Bingham, Lindy

    1995-01-01

    Goddard Space Flight Center (GSFC) on site and leased warehouses contain thousands of items of ground support equipment (GSE) and flight hardware including spacecraft, scaffolding, computer racks, stands, holding fixtures, test equipment, spares, etc. The control of these warehouses, and the management, accountability, and control of the items within them, is accomplished by the Logistics Management Division. To facilitate this management and tracking effort, the Logistics and Transportation Management Branch, is developing a system to provide warehouse personnel, property owners, and managers with storage and inventory information. This paper will describe that PC-based system and address how it will improve GSFC warehouse and storage management.

  2. Management of advanced primary urethral carcinomas.

    PubMed

    Dayyani, Farshid; Hoffman, Karen; Eifel, Patricia; Guo, Charles; Vikram, Raghu; Pagliaro, Lance C; Pettaway, Curtis

    2014-07-01

    Primary urethral carcinoma (PUC) is a rare malignancy accounting for <1% of genitourinary cancers, with a predilection for men and African-Americans. The sites and histology of urethral carcinoma vary by gender and anatomical location. Squamous cell carcinoma is most common among both genders but adenocarcinomas are noted in 15-35% of cases among women. Obstructive or irritative symptoms and haematuria are common modes of presentation. Clinical evaluation includes cystourethroscopy with biopsy and examination under anaesthesia. Magnetic resonance imaging provides a highly effective method to image the primary tumour while defıning the potential involvement of surrounding structures. Most tumours are localised, with regional metastases to nodal sites seen in up to 30% of cases in both genders, while distant metastases at presentation are rare (0-6%), but occur in up to 40% of cases with recurrent disease. Among men, the two most important prognostic factors are disease location and stage. Low-stage tumours (T1-2) and tumours involving the fossa navicularis or the penile urethra have a better prognosis than higher stage tumours (>T2 or N+) and lesions involving the bulbomembranous urethra. In women, in addition to stage and location, the size of the tumour has also prognostic implications. While surgery and radiation therapy (RT) are of benefit in early stage disease, advanced stage PUC requires multimodal treatment strategies to optimise local control and survival. These include induction chemotherapy followed by surgery or RT and concurrent chemoradiation with or without surgery. The latter strategy has been used successfully to treat other human papillomavirus-related cancers of the vagina, cervix and anus and may be of value in achieving organ preservation. Given the rarity of PUC, prospective multi-institutional studies are needed to better define the optimal treatment approach for this disease entity. PMID:24447439

  3. Advanced information processing system: Input/output network management software

    NASA Technical Reports Server (NTRS)

    Nagle, Gail; Alger, Linda; Kemp, Alexander

    1988-01-01

    The purpose of this document is to provide the software requirements and specifications for the Input/Output Network Management Services for the Advanced Information Processing System. This introduction and overview section is provided to briefly outline the overall architecture and software requirements of the AIPS system before discussing the details of the design requirements and specifications of the AIPS I/O Network Management software. A brief overview of the AIPS architecture followed by a more detailed description of the network architecture.

  4. Advances in Management of Pediatric Ependymomas.

    PubMed

    Lin, Frank Y; Chintagumpala, Murali

    2015-10-01

    Ependymomas are a heterogeneous group of neuroepithelial tumors of children and adults. In pediatric cases, the standard of care has long consisted of neurosurgical resection to the greatest extent acceptable followed by adjuvant involved field irradiation. Complete macroscopic surgical resection has remained the only consistent clinical variable known to improve survival. Adjuvant chemotherapy has yet to predictably affect outcome, possibly due to the molecular heterogeneity of histologically similar tumors. The administration of chemotherapy subsequently remains limited to clinical trials. However, recent comprehensive genomic, transcriptomic, and epigenetic interrogations of ependymomas have uncovered unique molecular characteristics and subtypes that correlated with clinical features such as age, neuroanatomical location, and prognosis. These findings represent a potential paradigm shift and provide a biologic rationale for targeted therapeutic strategies and risk-adapted administration of conventional treatment modalities. In this review, we focus on intracranial WHO grade II and III ependymoma of children and discuss conventional management strategies, followed by recent biologic findings and novel therapeutics currently under investigation. PMID:26369328

  5. Effects of vertical aperture on beam lifetime at the Advanced Photon Source (APS) storage ring

    SciTech Connect

    Bizek, H.M.

    1995-06-01

    When a positron`s energy deviation {delta}E/E exceeds the rf acceptance, or when it receives an angular kick for the betatron motion that exceeds some limiting admittance, the positron will be lost. The main contributions to the total beam lifetime come from single Coulomb and Touschek scattering. In this report we investigate the dependence of the residual gas pressure and the vertical aperture of the Advanced Photon Source storage ring on the total beam. lifetime. We present results of calculating the total beam lifetime as a function of vertical aperture for varying average ring pressure, beam current, and coupling coefficient.

  6. Advances in Clinical Management of Eosinophilic Esophagitis

    PubMed Central

    Dellon, Evan S.; Liacouras, Chris A.

    2014-01-01

    EoE is a chronic immune/antigen-mediated clinicopathologic condition that has become an increasingly important cause of upper gastrointestinal morbidity in adults and children over the past 2 decades. It is diagnosed based on symptoms of esophageal dysfunction, the presence of at least 15 eosinophils/high-power field in esophageal biopsies, and exclusion of competing causes of esophageal eosinophilia, including proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE). We review what we have recently learned about the clinical aspects of EoE, discussing the clinical, endoscopic, and histologic features of EoE in adults and children. We explain the current diagnostic criteria and challenges to diagnosis, including the role of gastroesophageal reflux disease and PPI-REE. It is also important to consider the epidemiology of EoE (current incidence of 1/10,000 new cases per year and prevalence of 0.5-1/1,000 cases per year) and disease progression. We review the main treatment approaches and new treatment options; EoE can be treated with topical corticosteroids such as fluticasone and budesonide, or dietary strategies, such as amino acid-based formulas, allergy test-directed elimination diets, and non-directed empiric elimination diets. Endoscopic dilation has also become an important tool for treatment of fibrostenostic complications of EoE. There are number of unresolved issues in EoE, including phenotypes, optimal treatment endpoints, the role of maintenance therapy, and treatment of refractory EoE. The care of patients with EoE and the study of the disease span many disciplines—EoE is ideally managed by a multidisciplinary team of gastroenterologists, allergists, pathologists, and dieticians. PMID:25109885

  7. A New Look at Managing the Small College Advancement Program.

    ERIC Educational Resources Information Center

    Willmer, Wesley K.

    Information about advancement programs at 190 small colleges is provided, with attention to recruitment/admissions, executive management, institutional relations, alumni, and fund raising. The 190 colleges, which responsed to a survey of members of the Council of Independent Colleges, are described according to enrollment size, geographic…

  8. 41 CFR 102-80.40 - What are Federal agencies' responsibilities concerning the management of underground storage tanks?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... agencies' responsibilities concerning the management of underground storage tanks? 102-80.40 Section 102-80... Environmental Management Underground Storage Tanks § 102-80.40 What are Federal agencies' responsibilities concerning the management of underground storage tanks? Federal agencies have the following...

  9. 41 CFR 102-80.40 - What are Federal agencies' responsibilities concerning the management of underground storage tanks?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... agencies' responsibilities concerning the management of underground storage tanks? 102-80.40 Section 102-80... Environmental Management Underground Storage Tanks § 102-80.40 What are Federal agencies' responsibilities concerning the management of underground storage tanks? Federal agencies have the following...

  10. 41 CFR 102-80.40 - What are Federal agencies' responsibilities concerning the management of underground storage tanks?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... agencies' responsibilities concerning the management of underground storage tanks? 102-80.40 Section 102-80... Environmental Management Underground Storage Tanks § 102-80.40 What are Federal agencies' responsibilities concerning the management of underground storage tanks? Federal agencies have the following...

  11. Resource Management and Risk Mitigation in Online Storage Grids

    ERIC Educational Resources Information Center

    Du, Ye

    2010-01-01

    This dissertation examines the economic value of online storage resources that could be traded and shared as potential commodities and the consequential investments and deployment of such resources. The value proposition of emergent business models such as Akamai and Amazon S3 in online storage grids is capacity provision and content delivery at…

  12. Advances in the Management of Treatment-Resistant Depression

    PubMed Central

    Holtzheimer, Paul E.

    2015-01-01

    Treatment-resistant depression (TRD) is a prevalent, disabling, and costly condition affecting 1%–4% of the U.S. population. Current approaches to managing TRD include medication augmentation (with lithium, thyroid hormone, buspirone, atypical antipsychotics, or various antidepressant medications), psychotherapy, and ECT. Advances in understanding the neurobiology of mood regulation and depression have led to a number of new potential approaches to managing TRD, including medications with novel mechanisms of action and focal brain stimulation techniques. This review will define and discuss the epidemiology of TRD, review the current approaches to its management, and then provide an overview of several developing interventions. PMID:25960694

  13. Selection of high temperature thermal energy storage materials for advanced solar dynamic space power systems

    NASA Technical Reports Server (NTRS)

    Lacy, Dovie E.; Coles-Hamilton, Carolyn; Juhasz, Albert

    1987-01-01

    Under the direction of NASA's Office of Aeronautics and Technology (OAST), the NASA Lewis Research Center has initiated an in-house thermal energy storage program to identify combinations of phase change thermal energy storage media for use with a Brayton and Stirling Advanced Solar Dynamic (ASD) space power system operating between 1070 and 1400 K. A study has been initiated to determine suitable combinations of thermal energy storage (TES) phase change materials (PCM) that result in the smallest and lightest weight ASD power system possible. To date the heats of fusion of several fluoride salt mixtures with melting points greater than 1025 K have been verified experimentally. The study has indicated that these salt systems produce large ASD systems because of their inherent low thermal conductivity and low density. It is desirable to have PCMs with high densities and high thermal conductivities. Therefore, alternate phase change materials based on metallic alloy systems are also being considered as possible TES candidates for future ASD space power systems.

  14. Multi-functional electrospun nanofibres for advances in tissue regeneration, energy conversion & storage, and water treatment.

    PubMed

    Peng, Shengjie; Jin, Guorui; Li, Linlin; Li, Kai; Srinivasan, Madhavi; Ramakrishna, Seeram; Chen, Jun

    2016-03-01

    Tissue regeneration, energy conversion & storage, and water treatment are some of the most critical challenges facing humanity in the 21st century. In order to address such challenges, one-dimensional (1D) materials are projected to play a key role in developing emerging solutions for the increasingly complex problems. Eletrospinning technology has been demonstrated to be a simple, versatile, and cost-effective method in fabricating a rich variety of materials with 1D nanostructures. These include polymers, composites, and inorganic materials with unique chemical and physical properties. In this tutorial review, we first give a brief introduction to electrospun materials with a special emphasis on the design, fabrication, and modification of 1D functional materials. Adopting the perspective of chemists and materials scientists, we then focus on the recent significant progress made in the domains of tissue regeneration (e.g., skin, nerve, heart and bone) and conversion & storage of clean energy (e.g., solar cells, fuel cells, batteries, and supercapacitors), where nanofibres have been used as active nanomaterials. Furthermore, this review's scope also includes the advances in the use of electrospun materials for the removal of heavy metal ions, organic pollutants, gas and bacteria in water treatment applications. Finally a conclusion and perspective is provided, in which we discuss the remaining challenges for 1D electrospun nanomaterials in tissue regeneration, energy conversion & storage, and water treatment. PMID:26727278

  15. Building and managing high performance, scalable, commodity mass storage systems

    NASA Technical Reports Server (NTRS)

    Lekashman, John

    1998-01-01

    The NAS Systems Division has recently embarked on a significant new way of handling the mass storage problem. One of the basic goals of this new development are to build systems at very large capacity and high performance, yet have the advantages of commodity products. The central design philosophy is to build storage systems the way the Internet was built. Competitive, survivable, expandable, and wide open. The thrust of this paper is to describe the motivation for this effort, what we mean by commodity mass storage, what the implications are for a facility that performs such an action, and where we think it will lead.

  16. 41 CFR 302-9.11 - May I receive an advance of funds for transportation and emergency storage of my POV?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of funds for transportation and emergency storage of my POV? 302-9.11 Section 302-9.11 Public... STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY STORAGE OF A PRIVATELY OWNED VEHICLE General Rules § 302-9.11 May I receive an advance of funds for transportation and emergency storage of...

  17. Organic nitrogen storage in mineral soil: implications for policy and management

    NASA Astrophysics Data System (ADS)

    Bingham, A. H.; Cotrufo, M. F.

    2015-06-01

    Nitrogen is one of the most important ecosystem nutrients and often its availability limits net primary production as well as stabilization of soil organic matter. The long-term storage of nitrogen-containing organic matter in soils was classically attributed to chemical complexity of plant and microbial residues that retarded microbial degradation. Recent advances have revised this framework, with the understanding that persistent soil organic matter consists largely of chemically labile, microbially processed organic compounds. Chemical bonding to minerals and physical protection in aggregates are more important to long-term (i.e., centuries to millennia) preservation of these organic compounds that contain the bulk of soil nitrogen rather than molecular complexity, with the exception of nitrogen in pyrogenic organic matter. This review examines the factors and mechanisms that influence the long-term sequestration of organic nitrogen in mineral soils. It examines the policy and management implications which stem from this newly accepted paradigm, such as critical loads considerations and nitrogen saturation and mitigation consequences. Finally, it emphasizes how essential it is for this important but underappreciated pool to be better quantified and incorporated into policy and management decisions.

  18. Intelligent Engine Systems: Thermal Management and Advanced Cooling

    NASA Technical Reports Server (NTRS)

    Bergholz, Robert

    2008-01-01

    The objective is to provide turbine-cooling technologies to meet Propulsion 21 goals related to engine fuel burn, emissions, safety, and reliability. Specifically, the GE Aviation (GEA) Advanced Turbine Cooling and Thermal Management program seeks to develop advanced cooling and flow distribution methods for HP turbines, while achieving a substantial reduction in total cooling flow and assuring acceptable turbine component safety and reliability. Enhanced cooling techniques, such as fluidic devices, controlled-vortex cooling, and directed impingement jets, offer the opportunity to incorporate both active and passive schemes. Coolant heat transfer enhancement also can be achieved from advanced designs that incorporate multi-disciplinary optimization of external film and internal cooling passage geometry.

  19. Management Strategies in Advanced Uterine Leiomyosarcoma: Focus on Trabectedin

    PubMed Central

    Amant, Frédéric; Lorusso, Domenica; Duffaud, Florence; Pautier, Patricia

    2015-01-01

    The treatment of advanced uterine leiomyosarcomas (U-LMS) represents a considerable challenge. Radiological diagnosis prior to hysterectomy is difficult, with the diagnosis frequently made postoperatively. Whilst a total abdominal hysterectomy is the cornerstone of management of early disease, the role of routine adjuvant pelvic radiotherapy and adjuvant chemotherapy is less clear, since they may improve local tumor control in high risk patients but are not associated with an overall survival benefit. For recurrent or disseminated U-LMS, cytotoxic chemotherapy remains the mainstay of treatment. There have been few active chemotherapy drugs approved for advanced disease, although newer drugs such as trabectedin with its pleiotropic mechanism of actions represent an important addition to the standard front-line systemic therapy with doxorubicin and ifosfamide. In this review, we outline the therapeutic potential and in particular the emerging evidence-based strategy of therapy with trabectedin in patients with advanced U-LMS. PMID:26089739

  20. Reservoir model for Hillsboro gas storage field management

    USGS Publications Warehouse

    Udegbunam, Emmanuel O.; Kemppainen, Curt; Morgan, Jim

    1995-01-01

    A 3-dimensional reservoir model is used to understand the behavior of the Hillsboro Gas Storage Field and to investigate the field's performance under various future development. Twenty-two years of the gas storage reservoir history, comprising the initial gas bubble development and seasonal gas injection and production cycles, are examined with a full-field, gas water, reservoir simulation model. The results suggest that the gas-water front is already in the vicinity of the west observation well that increasing the field's total gas-in-place volume would cause gas to migrate beyond the east, north and west observation well. They also suggest that storage enlargement through gas injection into the lower layers may not prevent gas migration. Moreover, the results suggest that the addition of strategically-located new wells would boost the simulated gas deliverabilities.

  1. Intelligent Engine Systems: Thermal Management and Advanced Cooling

    NASA Technical Reports Server (NTRS)

    Bergholz, Robert

    2008-01-01

    The objective of the Advanced Turbine Cooling and Thermal Management program is to develop intelligent control and distribution methods for turbine cooling, while achieving a reduction in total cooling flow and assuring acceptable turbine component safety and reliability. The program also will develop embedded sensor technologies and cooling system models for real-time engine diagnostics and health management. Both active and passive control strategies will be investigated that include the capability of intelligent modulation of flow quantities, pressures, and temperatures both within the supply system and at the turbine component level. Thermal management system concepts were studied, with a goal of reducing HPT blade cooling air supply temperature. An assessment will be made of the use of this air by the active clearance control system as well. Turbine component cooling designs incorporating advanced, high-effectiveness cooling features, will be evaluated. Turbine cooling flow control concepts will be studied at the cooling system level and the component level. Specific cooling features or sub-elements of an advanced HPT blade cooling design will be downselected for core fabrication and casting demonstrations.

  2. HOM damping with coaxial dampers in the storage ring cavities of the Advanced Photon Source

    SciTech Connect

    Kang, Y.W.; Kustom, R.L.

    1994-08-01

    Coaxial dampers with E-probe and H-loop couplers are used to damp higher-order modes (HOM) in a 352-MHz single cell cavity for the storage ring of the Advanced Photon Source (APS). Measurements have been made with three different types of dampers such as E-probe dampers, small H-loop dampers, and H-loop dampers with {lambda}/4 short stub. Two dampers are used in each type. The dampers without fundamental frequency rejection filters are positioned to have a minimum deQing at the fundamental frequency: the E-probe dampers are used at the equatorial plane of the cavity, and the small H-loop dampers are used in the end wall of the cavity. The fundamental mode decoupling can be done by positioning the loop plane in the direction of the H-field of the mode.

  3. Experience with Honeycrisp apple storage management in Washington

    Technology Transfer Automated Retrieval System (TEKTRAN)

    High demand and premium pricing have led to rapid increases in Honeycrisp plantings and fruit volume in Washington State, USA since introduction of the cultivar in 1999. Most fruit is packed and sold by January because of strong demand coupled with difficulties associated with extended storage. Howe...

  4. Unraveling apple fruit metabolism: Storage management opportunities and beyond

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple fruit has become a staple fruit commodity in many markets worldwide, making year-round availability crucial to retail chains. Consequently, apple storage practices have become increasingly sophisticated to meet rising quality expectations of fresh taste and a blemish free appearance. Modern ...

  5. Residue management to improve precipitation storage and water use efficiency

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Successful dryland crop production in semiarid environments is dependent upon efficient storage of precipitation and use of stored soil water supplies. The objectives of this presentation are to: 1. Summarize information regarding the effects of time of year; environmental parameters; residue orient...

  6. HYDRO BRAKE REGULATED STORAGE SYSTEM FOR STORMWATER MANAGEMENT

    EPA Science Inventory

    This research project was initiated with the overall objective of determining the ability of the Hydro Brake flow control device, in conjunction with off-line underground storage, to limit the rate of stormwater flow into combined sewers. The intended result of this control was t...

  7. Genetic and cultural management solutions to improve potato storage quality

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Potato storage quality is most easily described in terms of tuber attributes that maintain the value of the harvested crop. Among these attributes are attractive appearance, low shrink, low incidence of bruising and, for chip and fry processing varieties, specific gravity and reducing sugars appropr...

  8. Recent Advances in Management of Pediatric Food Allergy

    PubMed Central

    Anagnostou, Katherine; Swan, Kate; Fox, Adam T.

    2015-01-01

    Many children now suffer with a food allergy, immunoglobulin E (IgE) and/or non-IgE mediated. Food allergies have a significant impact on the child’s quality of life, as well as that of their family, due to the resultant dietary restrictions and the constant threat of a potentially life-threatening reaction. At present, there is no cure for food allergies, but there are exciting advances occurring in the management of IgE mediated allergies, including a more active approach to management with anticipatory screening testing, early introduction of common food allergens, active tolerance induction, use of biologics and active risk management. These areas will be discussed in this review. PMID:27417375

  9. Advanced methods of microscope control using μManager software

    PubMed Central

    Edelstein, Arthur D.; Tsuchida, Mark A.; Amodaj, Nenad; Pinkard, Henry; Vale, Ronald D.; Stuurman, Nico

    2014-01-01

    μManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, μManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced μManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging. PMID:25606571

  10. Recent Advances in Management of Pediatric Food Allergy.

    PubMed

    Anagnostou, Katherine; Swan, Kate; Fox, Adam T

    2015-01-01

    Many children now suffer with a food allergy, immunoglobulin E (IgE) and/or non-IgE mediated. Food allergies have a significant impact on the child's quality of life, as well as that of their family, due to the resultant dietary restrictions and the constant threat of a potentially life-threatening reaction. At present, there is no cure for food allergies, but there are exciting advances occurring in the management of IgE mediated allergies, including a more active approach to management with anticipatory screening testing, early introduction of common food allergens, active tolerance induction, use of biologics and active risk management. These areas will be discussed in this review. PMID:27417375

  11. FOREST MANAGEMENT AND THE ECONOMICS OF CARBON STORAGE: THE NONFINANCIAL COMPONENT

    EPA Science Inventory

    Interest has grown internationally in the past decade for stepping up management of world forests. his paper focuses on the economic considerations for forest management for carbon storage and argues for the need to include nonfinancial benefits and costs. sing a series of 30 pla...

  12. An Investigation to Advance the Technology Readiness Level of the Centaur Derived On-orbit Propellant Storage and Transfer System

    NASA Astrophysics Data System (ADS)

    Silvernail, Nathan L.

    This research was carried out in collaboration with the United Launch Alliance (ULA), to advance an innovative Centaur-based on-orbit propellant storage and transfer system that takes advantage of rotational settling to simplify Fluid Management (FM), specifically enabling settled fluid transfer between two tanks and settled pressure control. This research consists of two specific objectives: (1) technique and process validation and (2) computational model development. In order to raise the Technology Readiness Level (TRL) of this technology, the corresponding FM techniques and processes must be validated in a series of experimental tests, including: laboratory/ground testing, microgravity flight testing, suborbital flight testing, and orbital testing. Researchers from Embry-Riddle Aeronautical University (ERAU) have joined with the Massachusetts Institute of Technology (MIT) Synchronized Position Hold Engage and Reorient Experimental Satellites (SPHERES) team to develop a prototype FM system for operations aboard the International Space Station (ISS). Testing of the integrated system in a representative environment will raise the FM system to TRL 6. The tests will demonstrate the FM system and provide unique data pertaining to the vehicle's rotational dynamics while undergoing fluid transfer operations. These data sets provide insight into the behavior and physical tendencies of the on-orbit refueling system. Furthermore, they provide a baseline for comparison against the data produced by various computational models; thus verifying the accuracy of the models output and validating the modeling approach. Once these preliminary models have been validated, the parameters defined by them will provide the basis of development for accurate simulations of full scale, on-orbit systems. The completion of this project and the models being developed will accelerate the commercialization of on-orbit propellant storage and transfer technologies as well as all in

  13. Storage management in Ada. Three reports. Volume 1: Storage management in Ada as a risk to the development of reliable software. Volume 2: Relevant aspects of language. Volume 3: Requirements of the language versus manifestations of current implementations

    NASA Technical Reports Server (NTRS)

    Auty, David

    1988-01-01

    The risk to the development of program reliability is derived from the use of a new language and from the potential use of new storage management techniques. With Ada and associated support software, there is a lack of established guidelines and procedures, drawn from experience and common usage, which assume reliable behavior. The risk is identified and clarified. In order to provide a framework for future consideration of dynamic storage management on Ada, a description of the relevant aspects of the language is presented in two sections: Program data sources, and declaration and allocation in Ada. Storage-management characteristics of the Ada language and storage-management characteristics of Ada implementations are differentiated. Terms that are used are defined in a narrow and precise sense. The storage-management implications of the Ada language are described. The storage-management options available to the Ada implementor and the implications of the implementor's choice for the Ada programmer are also described.

  14. Towards Efficient Scientific Data Management Using Cloud Storage

    NASA Technical Reports Server (NTRS)

    He, Qiming

    2013-01-01

    A software prototype allows users to backup and restore data to/from both public and private cloud storage such as Amazon's S3 and NASA's Nebula. Unlike other off-the-shelf tools, this software ensures user data security in the cloud (through encryption), and minimizes users operating costs by using space- and bandwidth-efficient compression and incremental backup. Parallel data processing utilities have also been developed by using massively scalable cloud computing in conjunction with cloud storage. One of the innovations in this software is using modified open source components to work with a private cloud like NASA Nebula. Another innovation is porting the complex backup to- cloud software to embedded Linux, running on the home networking devices, in order to benefit more users.

  15. Understanding and Managing Aging of Spent Nuclear Fuel and Facility Components in Wet Storage

    SciTech Connect

    Johnson, A. Burton

    2007-07-01

    Storage of nuclear fuel after it has been discharged from reactors has become the leading spent fuel management option. Many storage facilities are being required to operate longer than originally anticipated. Aging is a term that has emerged to focus attention on the consequences of extended operation on systems, structures, and components that comprise the storage facilities. The key to mitigation of age-related degradation in storage facilities is to implement effective strategies to understand and manage aging of the facility materials. A systematic approach to preclude serious effects of age-related degradation is addressed in this paper, directed principally to smaller facilities (test and research reactors). The first need is to assess the materials that comprise the facility and the environments that they are subject to. Access to historical data on facility design, fabrication, and operation can facilitate assessment of expected materials performance. Methods to assess the current condition of facility materials are summarized in the paper. Each facility needs an aging management plan to define the scope of the management program, involving identification of the materials that need specific actions to manage age-related degradation. For each material identified, one or more aging management programs are developed and become part of the plan Several national and international organizations have invested in development of comprehensive and systematic approaches to aging management. A method developed by the US Nuclear Regulatory Commission is recommended as a concise template to organize measures to effectively manage age-related degradation of storage facility materials, including the scope of inspection, surveillance, and maintenance that is needed to assure successful operation of the facility over its required life. Important to effective aging management is a staff that is alert for evidence of materials degradation and committed to carry out the aging

  16. Engineering management of Underground Storage Tank upgrades and installations

    SciTech Connect

    Patel, P.B.

    1994-07-01

    Remediation of Leaking Underground Storage Tanks (LUST) is estimated to cost more than $41 billion in the United States. As of May 1992, 1.5 million Underground Storage Tanks were registered in USA. By September 1992, 184,000 confirmed releases (leaks) were reported in USA. Due to such a vast impact on the environment due to leaking USTS, United States Environmental Protection Agency (USEPA) published final UST regulations in the Federal Register on September 23,1988 (40CFR Part 280) which affected almost every commercial underground storage tank (UST). In a rush to comply with UST regulations, it is important that sufficient attention has been paid to engineering aspects of the work. Due to wide array of UST leak prevention and detection products available, selection of appropriate instrumentation can be time consuming. Most states have taken federal government standards on USTs and incorporated them as state regulations with their state specific modifications depending on their local geological conditions and environmental priorities. However, it is important to find out that state`s UST program has been approved by USEPA. This paper consists of discussion of issues based on the author`s UST project related experience from current and previous employment. Following are the major UST related regulatory topics discussed in this paper: Specifications;Hiring a contractor; Piping Selection and Installation; UST Selection and Installation; Leak Detection System Environmental Sampling.

  17. Disk storage management for LHCb based on Data Popularity estimator

    NASA Astrophysics Data System (ADS)

    Hushchyn, Mikhail; Charpentier, Philippe; Ustyuzhanin, Andrey

    2015-12-01

    This paper presents an algorithm providing recommendations for optimizing the LHCb data storage. The LHCb data storage system is a hybrid system. All datasets are kept as archives on magnetic tapes. The most popular datasets are kept on disks. The algorithm takes the dataset usage history and metadata (size, type, configuration etc.) to generate a recommendation report. This article presents how we use machine learning algorithms to predict future data popularity. Using these predictions it is possible to estimate which datasets should be removed from disk. We use regression algorithms and time series analysis to find the optimal number of replicas for datasets that are kept on disk. Based on the data popularity and the number of replicas optimization, the algorithm minimizes a loss function to find the optimal data distribution. The loss function represents all requirements for data distribution in the data storage system. We demonstrate how our algorithm helps to save disk space and to reduce waiting times for jobs using this data.

  18. Recent advances in the management of Hodgkin lymphoma

    PubMed Central

    Villasboas, Jose C.; Ansell, Stephen M.

    2016-01-01

    Hodgkin lymphoma (HL) is a rare cancer of the immune system that typically affects lymph nodes and sometimes other organs. Although the majority of patients can be potentially cured with the use of multi-agent chemotherapy and radiotherapy, a proportion of them will relapse or develop resistant disease for which treatment options are limited. In recent years, new agents have been developed and tested in HL with encouraging results. Two classes of drugs stand out as highly active in advanced HL based on recent study results: antibody-drug conjugates and programmed death 1 inhibitors. Clinical trials in HL with these agents have been completed in the past several years and the results have recently become available. In this review, we discuss the recent advances in the management of HL with a focus on strategies to decrease toxicity and a review of the two drug classes that have the potential to change the landscape of treatment of this disease. PMID:27158471

  19. Recent advances in the management of Hodgkin lymphoma.

    PubMed

    Villasboas, Jose C; Ansell, Stephen M

    2016-01-01

    Hodgkin lymphoma (HL) is a rare cancer of the immune system that typically affects lymph nodes and sometimes other organs. Although the majority of patients can be potentially cured with the use of multi-agent chemotherapy and radiotherapy, a proportion of them will relapse or develop resistant disease for which treatment options are limited. In recent years, new agents have been developed and tested in HL with encouraging results. Two classes of drugs stand out as highly active in advanced HL based on recent study results: antibody-drug conjugates and programmed death 1 inhibitors. Clinical trials in HL with these agents have been completed in the past several years and the results have recently become available. In this review, we discuss the recent advances in the management of HL with a focus on strategies to decrease toxicity and a review of the two drug classes that have the potential to change the landscape of treatment of this disease. PMID:27158471

  20. Advanced thermal management needs for Lunar and Mars missions

    SciTech Connect

    Klein, A.C. ); Webb, B.J. )

    1993-01-15

    Significant improvements in thermal management technologies will be required to support NASA's planned Lunar and Mars missions. The developments needed include the application of advanced materials to reduce radiator system masses, enhanced survivability, and the use of alternative working fluids. Current thermal management systems utilize one of two heat rejection alternatives; either single phase pumped loops, or two phase heat pipes constructed with thick walled metal casings. These two technologies have proven themselves to be reliable performers in the transport and rejection of waste heat from spacecraft. As thermal management needs increase with increased power consumption and activity required on spacecraft, these metal based thermal management systems will become mission limiting. Investigations into the use of light weight ceramic materials for high temperature thermal management systems have been conducted by NASA, the Department of Energy, and the Department of Defense since the early 1980s, with results showing that significant mass savings can be obtained by replacing some of the metallic functions with ceramic materials.

  1. Pharmacotherapy Considerations for the Management of Advanced Cardiac Life Support.

    PubMed

    Beavers, Craig J; Pandya, Komal A

    2016-03-01

    Health care providers should be aware of the pharmacotherapy considerations in the American Heart Association's guidelines for advanced cardiac life support (ACLS). Current evidence does not suggest a reduction in mortality with ACLS medications; however, these medications can improve return of spontaneous circulation. Proper agent selection and dosing are imperative to maximize benefit and minimize harm. The latest guideline update included major changes to the ventricular fibrillation/pulseless ventricular tachycardia and pulseless electrical activity/asystole algorithms, which providers should adopt. It is critical that providers be prepared for post-code management. Health care professionals should remain abreast of changing evidence and guidelines. PMID:26897425

  2. Advanced construction management for lunar base construction - Surface operations planner

    NASA Technical Reports Server (NTRS)

    Kehoe, Robert P.

    1992-01-01

    The study proposes a conceptual solution and lays the framework for developing a new, sophisticated and intelligent tool for a lunar base construction crew to use. This concept integrates expert systems for critical decision making, virtual reality for training, logistics and laydown optimization, automated productivity measurements, and an advanced scheduling tool to form a unique new planning tool. The concept features extensive use of computers and expert systems software to support the actual work, while allowing the crew to control the project from the lunar surface. Consideration is given to a logistics data base, laydown area management, flexible critical progress scheduler, video simulation of assembly tasks, and assembly information and tracking documentation.

  3. Advanced fuels for plutonium management in pressurized water reactors

    NASA Astrophysics Data System (ADS)

    Vasile, A.; Dufour, Ph; Golfier, H.; Grouiller, J. P.; Guillet, J. L.; Poinot, Ch; Youinou, G.; Zaetta, A.

    2003-06-01

    Several fuel concepts are under investigation at CEA with the aim of manage plutonium inventories in pressurized water reactors. This options range from the use of mature technologies like MOX adapted in the case of MOX-EUS (enriched uranium support) and COmbustible Recyclage A ILot (CORAIL) assemblies to more innovative technologies using IMF like DUPLEX and advanced plutonium assembly (APA). The plutonium burning performances reported to the electrical production go from 7 to 60 kg (TW h) -1. More detailed analysis covering economic, sustainability, reliability and safety aspects and their integration in the whole fuel cycle would allow identifying the best candidate.

  4. Safety Aspects of Dry Spent Fuel Storage and Spent Fuel Management - 13559

    SciTech Connect

    Botsch, W.; Smalian, S.; Hinterding, P.

    2013-07-01

    casks fulfills both transport and storage requirements. Mostly, storage facilities are designed as concrete buildings above the ground, but due to regional constraints, one storage facility has also been built as a rock tunnel. The decay heat is always removed by natural air flow; further technical equipment is not needed. The removal of decay heat and shielding had been modeled and calculated by state-of-the-art computer codes before such a facility has been built. TueV and BAM present their long experience in the licensing process for sites and casks and inform about spent nuclear fuel management and issues concerning dry storage of spent nuclear fuel. Different storage systems and facilities in Germany, Europe and world-wide are compared with respect to the safety aspects mentioned above. Initial points are the safety issues of wet storage of SF, and it is shown how dry storage systems can ensure the compliance with the mentioned safety criteria over a long storage period. The German storage concept for dry storage of SF and HLW is presented and discussed. Exemplarily, the process of licensing, erection and operation of selected German dry storage facilities is presented. (authors)

  5. Cryogenic Fluid Management Technologies for Advanced Green Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Motil, Susan M.; Meyer, Michael L.; Tucker, Stephen P.

    2007-01-01

    In support of the Exploration Vision for returning to the Moon and beyond, NASA and its partners are developing and testing critical cryogenic fluid propellant technologies that will meet the need for high performance propellants on long-term missions. Reliable knowledge of low-gravity cryogenic fluid management behavior is lacking and yet is critical in the areas of tank thermal and pressure control, fluid acquisition, mass gauging, and fluid transfer. Such knowledge can significantly reduce or even eliminate tank fluid boil-off losses for long term missions, reduce propellant launch mass and required on-orbit margins, and simplify vehicle operations. The Propulsion and Cryogenic Advanced Development (PCAD) Project is performing experimental and analytical evaluation of several areas within Cryogenic Fluid Management (CFM) to enable NASA's Exploration Vision. This paper discusses the status of the PCAD CFM technology focus areas relative to the anticipated CFM requirements to enable execution of the Vision for Space Exploration.

  6. Recent advances in the management of acute bronchiolitis

    PubMed Central

    Ravaglia, Claudia

    2014-01-01

    Acute bronchiolitis is characterized by acute wheezing in infants or children and is associated with signs or symptoms of respiratory infection; it is rarely symptomatic in adults and the most common etiologic agent is respiratory syncytial virus (RSV). Usually it does not require investigation, treatment is merely supportive and a conservative approach seems adequate in the majority of children, especially for the youngest ones (<3 months); however, clinical scoring systems have been proposed and admission in hospital should be arranged in case of severe disease or a very young age or important comorbidities. Apnea is a very important aspect of the management of young infants with bronchiolitis. This review focuses on the clinical, radiographic, and pathologic characteristics, as well as the recent advances in management of acute bronchiolitis. PMID:25580257

  7. Recent advances in the prevention and management of preterm birth

    PubMed Central

    Tan, Min Yi

    2015-01-01

    The management of preterm birth has seen major transformations in the last few decades with increasing interest worldwide, due to the impact of preterm birth on neonatal morbidity and mortality. The prevention strategies currently available for asymptomatic women at risk of preterm birth include progesterone, cervical cerclage and cervical pessary. Each approach has varying effects depending on the patient's prior history of preterm birth, cervical length and the presence of multiple gestations. There is a shift in the focus of antenatal treatment, with the use of prenatal magnesium sulphate and corticosteroids, to reduce neonatal intensive care admissions and longer-term disabilities associated with preterm birth, consequently relieving emotional and economical burden. This article provides an update on the recent advances in prevention and management approaches available for women at risk of preterm birth. PMID:26097713

  8. User and group storage management the CMS CERN T2 centre

    NASA Astrophysics Data System (ADS)

    Cerminara, G.; Franzoni, G.; Pfeiffer, A.

    2015-12-01

    A wide range of detector commissioning, calibration and data analysis tasks is carried out by CMS using dedicated storage resources available at the CMS CERN Tier-2 centre. Relying on the functionalities of the EOS disk-only storage technology, the optimal exploitation of the CMS user/group resources has required the introduction of policies for data access management, data protection, cleanup campaigns based on access pattern, and long term tape archival. The resource management has been organised around the definition of working groups and the delegation to an identified responsible of each group composition. In this paper we illustrate the user/group storage management, and the development and operational experience at the CMS CERN Tier-2 centre in the 2012-2015 period.

  9. Development of advanced manufacturing technologies for low cost hydrogen storage vessels

    SciTech Connect

    Leavitt, Mark; Lam, Patrick

    2014-12-29

    The U.S. Department of Energy (DOE) defined a need for low-cost gaseous hydrogen storage vessels at 700 bar to support cost goals aimed at 500,000 units per year. Existing filament winding processes produce a pressure vessel that is structurally inefficient, requiring more carbon fiber for manufacturing reasons, than would otherwise be necessary. Carbon fiber is the greatest cost driver in building a hydrogen pressure vessel. The objective of this project is to develop new methods for manufacturing Type IV pressure vessels for hydrogen storage with the purpose of lowering the overall product cost through an innovative hybrid process of optimizing composite usage by combining traditional filament winding (FW) and advanced fiber placement (AFP) techniques. A numbers of vessels were manufactured in this project. The latest vessel design passed all the critical tests on the hybrid design per European Commission (EC) 79-2009 standard except the extreme temperature cycle test. The tests passed include burst test, cycle test, accelerated stress rupture test and drop test. It was discovered the location where AFP and FW overlap for load transfer could be weakened during hydraulic cycling at 85°C. To design a vessel that passed these tests, the in-house modeling software was updated to add capability to start and stop fiber layers to simulate the AFP process. The original in-house software was developed for filament winding only. Alternative fiber was also investigated in this project, but the added mass impacted the vessel cost negatively due to the lower performance from the alternative fiber. Overall the project was a success to show the hybrid design is a viable solution to reduce fiber usage, thus driving down the cost of fuel storage vessels. Based on DOE’s baseline vessel size of 147.3L and 91kg, the 129L vessel (scaled to DOE baseline) in this project shows a 32% composite savings and 20% cost savings when comparing Vessel 15 hybrid design and the Quantum

  10. Genetics of Lipid-Storage Management in Caenorhabditis elegans Embryos.

    PubMed

    Schmökel, Verena; Memar, Nadin; Wiekenberg, Anne; Trotzmüller, Martin; Schnabel, Ralf; Döring, Frank

    2016-03-01

    Lipids play a pivotal role in embryogenesis as structural components of cellular membranes, as a source of energy, and as signaling molecules. On the basis of a collection of temperature-sensitive embryonic lethal mutants, a systematic database search, and a subsequent microscopic analysis of >300 interference RNA (RNAi)-treated/mutant worms, we identified a couple of evolutionary conserved genes associated with lipid storage in Caenorhabditis elegans embryos. The genes include cpl-1 (cathepsin L-like cysteine protease), ccz-1 (guanine nucleotide exchange factor subunit), and asm-3 (acid sphingomyelinase), which is closely related to the human Niemann-Pick disease-causing gene SMPD1. The respective mutant embryos accumulate enlarged droplets of neutral lipids (cpl-1) and yolk-containing lipid droplets (ccz-1) or have larger genuine lipid droplets (asm-3). The asm-3 mutant embryos additionally showed an enhanced resistance against C band ultraviolet (UV-C) light. Herein we propose that cpl-1, ccz-1, and asm-3 are genes required for the processing of lipid-containing droplets in C. elegans embryos. Owing to the high levels of conservation, the identified genes are also useful in studies of embryonic lipid storage in other organisms. PMID:26773047

  11. Biosafety in embryos and semen cryopreservation, storage, management and transport.

    PubMed

    Bielanski, A

    2014-01-01

    This chapter summarizes pertinent procedures, data and opinions on the potential hazards of disease transmission through liquid nitrogen (LN)-cryopreserved and banked germplasm and tissues for somatic cell nuclear transfer (SCNT) The importance of applying internationally adopted sanitary washing procedures to germplasm as a crucial step towards their successful microbial-free cryopreservation and storage is emphasised. Special attention is given to the survival of pathogens in LN, variety of vitrification methods, sterility of LN, risks associated with the use of straws and cryovials, and LN Dewars including dry shippers. It was experimentally demonstrated that cross-contamination between LN and embryos may occur, when infectious agents are present in LN and if embryos are not protected by use of a sealed container. It is important, therefore, to prevent direct contact of germplasm and reproductive tissues with LN during cryopreservation and their storage as a mandatory measure for reducing the risk of contamination. This includes the usage of hermetically sealed high quality shatter proof freezing containers and/or the application of a secondary enclosure such as "double bagging or straw in straw". A periodic disinfection of cryo-Dewars should be considered as an additional precaution to diminish the potential for inadvertent cross-contamination. It would be advisable to use separate LN Dewars to quarantine embryos derived from infected donors of valuable genotypes or from unknown health status, extinction-threatened species. PMID:25091919

  12. Managing high-bandwidth real-time data storage

    SciTech Connect

    Bigelow, David D.; Brandt, Scott A; Bent, John M; Chen, Hsing-Bung

    2009-09-23

    There exist certain systems which generate real-time data at high bandwidth, but do not necessarily require the long-term retention of that data in normal conditions. In some cases, the data may not actually be useful, and in others, there may be too much data to permanently retain in long-term storage whether it is useful or not. However, certain portions of the data may be identified as being vitally important from time to time, and must therefore be retained for further analysis or permanent storage without interrupting the ongoing collection of new data. We have developed a system, Mahanaxar, intended to address this problem. It provides quality of service guarantees for incoming real-time data streams and simultaneous access to already-recorded data on a best-effort basis utilizing any spare bandwidth. It has built in mechanisms for reliability and indexing, can scale upwards to meet increasing bandwidth requirements, and handles both small and large data elements equally well. We will show that a prototype version of this system provides better performance than a flat file (traditional filesystem) based version, particularly with regard to quality of service guarantees and hard real-time requirements.

  13. Solid Waste Management Requirements Definition for Advanced Life Support Missions: Results

    NASA Technical Reports Server (NTRS)

    Alazraki, Michael P.; Hogan, John; Levri, Julie; Fisher, John; Drysdale, Alan

    2002-01-01

    Prior to determining what Solid Waste Management (SWM) technologies should be researched and developed by the Advanced Life Support (ALS) Project for future missions, there is a need to define SWM requirements. Because future waste streams will be highly mission-dependent, missions need to be defined prior to developing SWM requirements. The SWM Working Group has used the mission architecture outlined in the System Integration, Modeling and Analysis (SIMA) Element Reference Missions Document (RMD) as a starting point in the requirement development process. The missions examined include the International Space Station (ISS), a Mars Dual Lander mission, and a Mars Base. The SWM Element has also identified common SWM functionalities needed for future missions. These functionalities include: acceptance, transport, processing, storage, monitoring and control, and disposal. Requirements in each of these six areas are currently being developed for the selected missions. This paper reviews the results of this ongoing effort and identifies mission-dependent resource recovery requirements.

  14. Advanced data management design for autonomous telerobotic systems in space using spaceborne symbolic processors

    NASA Technical Reports Server (NTRS)

    Goforth, Andre

    1987-01-01

    The use of computers in autonomous telerobots is reaching the point where advanced distributed processing concepts and techniques are needed to support the functioning of Space Station era telerobotic systems. Three major issues that have impact on the design of data management functions in a telerobot are covered. It also presents a design concept that incorporates an intelligent systems manager (ISM) running on a spaceborne symbolic processor (SSP), to address these issues. The first issue is the support of a system-wide control architecture or control philosophy. Salient features of two candidates are presented that impose constraints on data management design. The second issue is the role of data management in terms of system integration. This referes to providing shared or coordinated data processing and storage resources to a variety of telerobotic components such as vision, mechanical sensing, real-time coordinated multiple limb and end effector control, and planning and reasoning. The third issue is hardware that supports symbolic processing in conjunction with standard data I/O and numeric processing. A SSP that currently is seen to be technologically feasible and is being developed is described and used as a baseline in the design concept.

  15. Managing addiction in advanced cancer patients: why bother?

    PubMed

    Passik, S D; Theobald, D E

    2000-03-01

    The management of addiction in patients with advanced cancer can be time-consuming, labor-intensive, and difficult. Some clinicians believe that it is not worth the effort, due in part to a failure to appreciate the deleterious impact of addiction on palliative care efforts and a view of addiction as intractable in any case. Indeed, it is possible that some clinicians perceive addiction not only fatalistically but, because of common misconceptions, believe that managing or attempting to decrease the patient's use of alcohol or illicit substances would be tantamount to depriving a dying patient of a source of pleasure. In this paper, we argue that managing addiction is an essential aspect of palliative care for chemically-dependent and alcoholic patients. The goal of such efforts is not complete abstinence, but exerting enough control over illicit drug and alcohol use to allow palliative care interventions to decrease suffering. To illustrate this view, we describe two patients with chemical-dependency. We highlight the impact of unchecked substance abuse on patients' perpetuation of their own suffering, the complication of symptom management, the diagnosis and treatment of mood/anxiety disorders, and the effect on the patients' family and caregivers. PMID:10760628

  16. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume 2

    SciTech Connect

    Not Available

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

  17. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume1

    SciTech Connect

    Not Available

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723).DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations:Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho;Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

  18. Waste Management Planned for the Advanced Fuel Cycle Facility

    SciTech Connect

    Soelberg

    2007-09-01

    The U.S. Department of Energy (DOE) Global Nuclear Energy Partnership (GNEP) program has been proposed to develop and employ advanced technologies to increase the proliferation resistance of spent nuclear fuels, recover and reuse nuclear fuel resources, and reduce the amount of wastes requiring permanent geological disposal. In the initial GNEP fuel cycle concept, spent nuclear fuel is to be reprocessed to separate re-useable transuranic elements and uranium from waste fission products, for fabricating new fuel for fast reactors. The separated wastes would be converted to robust waste forms for disposal. The Advanced Fuel Cycle Facility (AFCF) is proposed by DOE for developing and demonstrating spent nuclear fuel recycling technologies and systems. The AFCF will include capabilities for receiving and reprocessing spent fuel and fabricating new nuclear fuel from the reprocessed spent fuel. Reprocessing and fuel fabrication activities will generate a variety of radioactive and mixed waste streams. Some of these waste streams are unique and unprecedented. The GNEP vision challenges traditional U.S. radioactive waste policies and regulations. Product and waste streams have been identified during conceptual design. Waste treatment technologies have been proposed based on the characteristics of the waste streams and the expected requirements for the final waste forms. Results of AFCF operations will advance new technologies that will contribute to safe and economical commercial spent fuel reprocessing facilities needed to meet the GNEP vision. As conceptual design work and research and design continues, the waste management strategies for the AFCF are expected to also evolve.

  19. Prognostics Health Management for Advanced Small Modular Reactor Passive Components

    SciTech Connect

    Meyer, Ryan M.; Ramuhalli, Pradeep; Coble, Jamie B.; Mitchell, Mark R.; Wootan, David W.; Hirt, Evelyn H.; Berglin, Eric J.; Bond, Leonard J.; Henager, Charles H.

    2013-10-18

    In the United States, sustainable nuclear power to promote energy security is a key national energy priority. Advanced small modular reactors (AdvSMR), which are based on modularization of advanced reactor concepts using non-light-water reactor (LWR) coolants such as liquid metal, helium, or liquid salt may provide a longer-term alternative to more conventional LWR-based concepts. The economics of AdvSMRs will be impacted by the reduced economy-of-scale savings when compared to traditional LWRs and the controllable day-to-day costs of AdvSMRs are expected to be dominated by operations and maintenance costs. Therefore, achieving the full benefits of AdvSMR deployment requires a new paradigm for plant design and management. In this context, prognostic health management of passive components in AdvSMRs can play a key role in enabling the economic deployment of AdvSMRs. In this paper, the background of AdvSMRs is discussed from which requirements for PHM systems are derived. The particle filter technique is proposed as a prognostics framework for AdvSMR passive components and the suitability of the particle filter technique is illustrated by using it to forecast thermal creep degradation using a physics-of-failure model and based on a combination of types of measurements conceived for passive AdvSMR components.

  20. Advances in the management of acute liver failure

    PubMed Central

    Wang, Da-Wei; Yin, Yi-Mei; Yao, Yong-Ming

    2013-01-01

    Acute liver failure (ALF) is an uncommon but dramatic clinical syndrome characterized by hepatic encephalopathy and a bleeding tendency due to abrupt loss of liver function caused by massive or submassive liver necrosis in a patient with a previously healthy liver. The causes of ALF encompass a wide variety of toxic, viral, metabolic, vascular and autoimmune insults to the liver, and identifying the correct cause can be difficult or even impossible. Many patients with ALF develop a cascade of serious complications involving almost every organ system, and death is mostly due to multi-organ failure, hemorrhage, infection, and intracranial hypertension. Fortunately, the outcome of ALF has been improved in the last 3 decades through the specific treatment for the disease of certain etiology, and the advanced intensive care management. For most severely affected patients who fail to recover after treatment, rapid evaluation for transfer to a transplantation center and consideration for liver transplantation is mandatory so that transplantation can be applied before contraindications develop. This review focuses on the recent advances in the understanding of various contributing etiologies, the administration of etiology-specific treatment to alleviate the liver injury, and the management of complications (e.g., encephalopathy, coagulopathy, cardiovascular instability, respiratory failure, renal failure, sepsis and metabolic disturbance) in patients with ALF. Assessment of the need for liver transplantation is also presented. PMID:24222950

  1. Advanced crisis response and consequence management: enabling a coordinated response

    NASA Astrophysics Data System (ADS)

    Williams, Robert S.; Brush, Jennifer L.; Heinrich, Mark L.; Mantock, James M.; Jones, Brian E.; Henry, Kurt A.

    2002-08-01

    The Defense Advanced Research Projects Agency (DARPA) envisioned a system to assist decision-makers during crisis situations ranging from terrorist attacks to large-scale natural disasters. This system would provide the tools for responders, incident commanders, and officials at all levels to share vital information during the planning and execution of a coordinated response. The system would offer custom configuration of components with capabilities including map-based situational awareness, situation-based response checklists, casualty tracking, and epidemiological surveillance. On-scene commanders would use this system to document the progress of a response, direct and coordinate responder activities, and manage the response as a whole. Off-scene responders (hospitals, command centers, and local, state and federal agencies) would have the ability to visually assess the state of assets and casualties to better anticipate the need for personnel and supplies. DARPA's Enhanced Consequence Management, Planning and Support System (ENCOMPASS), successfully demonstrated all of these capabilities. ENCOMPASS was successfully transitioned to a commercial program: the Lightweight Epidemiology Advanced Detection and Emergency Response System, otherwise known as LEADERS.

  2. Effect of tree line advance on carbon storage in NW Alaska

    USGS Publications Warehouse

    Wilmking, M.; Harden, J.; Tape, K.

    2006-01-01

    We investigated the size, distribution, and temporal dynamics of ecosystem carbon (C) pools in an area of recent tree line advance, northwest Alaska. Repeat aerial photographs show forest cover increased ???10% in our study area since 1949. We sampled C pools of four principal ecosystem types, tussock tundra, shrub tundra, woodland, and forest, all located on a 600-800 year old river terrace. Significant differences between ecosystem C pools, both above ground and below ground existed. Tundra sites store >22.2 kg C/m2, shrub tundra sites and woodland sites store 9.7 kg C/m2 and 14.3 kg C/m2, respectively, and forest sites store 14.4 kg C/m2. Landscape variation of total ecosystem C was primarily due to organic soil C and was secondarily due to C stored in trees. Soil C/N profiles of shrub tundra sites and woodland sites showed similarities with forest site soils at surface and tundra site soils at depth. We hypothesize that tundra systems transformed to forest systems in this area under a progression of permafrost degradation and enhanced drainage. On the basis of C pool estimates for the different ecosystem types, conversion of tundra sites to forest may have resulted in a net loss of > 7.8 kg C/m2, since aboveground C gains were more than offset by belowground C losses to decomposition in the tundra sites. Tree line advance therefore might not increase C storage in high-latitude ecosystems and thus might not, as previously suggested, act as a negative feedback to warming. Key to this hypothesis and to its projection to future climate response is the fate of soil carbon upon warming and permafrost drainage. Copyright 2006 by the American Geophysical Union.

  3. Digital closed orbit feedback system for the Advanced Photon Source storage ring

    NASA Astrophysics Data System (ADS)

    Chung, Y.; Barr, D.; Decker, G.; Galayda, J.; Lenkszus, F.; Lumpkin, A.; Votaw, A. J.

    1996-09-01

    Closed orbit feedback for the Advanced Photon Source (APS) storage ring employs unified global and local feedback systems for stabilization of particle and photon beams based on digital signal processing. Hardware and software aspects of the system will be described. In particular, we will discuss global and local orbit feedback algorithms, PID (proportional, integral, and derivative) control algorithm, application of digital signal processing to compensate for vacuum chamber eddy current effects, resolution of the interaction between global and local systems through decoupling, self-correction of the local bump closure error, user interface through the APS control system, and system performance in the frequency and time domains. The system hardware, including the digital signal processor (DSPs), is distributed in 20 VME crates around the ring, and the entire feedback system runs synchronously at 4-kHz sampling frequency in order to achieve a correction bandwidth exceeding 100 Hz. The required data sharing between the global and local feedback systems is facilitated via the use of fiber-optically networked reflective memories.

  4. Advances in photonics thermal management and packaging materials

    NASA Astrophysics Data System (ADS)

    Zweben, Carl

    2008-02-01

    Heat dissipation, thermal stresses, and cost are key packaging design issues for virtually all semiconductors, including photonic applications such as diode lasers, light-emitting diodes (LEDs), solid state lighting, photovoltaics, displays, projectors, detectors, sensors and laser weapons. Heat dissipation and thermal stresses affect performance and reliability. Copper, aluminum and conventional polymeric printed circuit boards (PCBs) have high coefficients of thermal expansion, which can cause high thermal stresses. Most traditional low-coefficient-of-thermal-expansion (CTE) materials like tungsten/copper, which date from the mid 20 th century, have thermal conductivities that are no better than those of aluminum alloys, about 200 W/m-K. There are an increasing number of low-CTE materials with thermal conductivities ranging between that of copper (400 W/m-K) and 1700 W/m-K, and many other new low-CTE materials with lower thermal conductivities. An important benefit of low-CTE materials is that they allow use of hard solders. Some advanced materials are low cost. Others have the potential to be low cost in high-volume production. High-thermal-conductivity materials enable higher power levels, potentially reducing the number of required devices. Advanced thermal materials can constrain PCB CTE and greatly increase thermal conductivity. This paper reviews traditional packaging materials and advanced thermal management materials. The latter provide the packaging engineer with a greater range of options than in the past. Topics include properties, status, applications, cost, using advanced materials to fix manufacturing problems, and future directions, including composites reinforced with carbon nanotubes and other thermally conductive materials.

  5. 78 FR 23548 - Draft Supplemental Environmental Impact Statement for the Long-Term Management and Storage of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... issued the Mercury Storage EIS in January 2011 (76 FR 5145). The Mercury Storage EIS and related NEPA... (77 FR 33204). DOE held two public meetings during a 30-day public scoping period and considered all... Supplemental Environmental Impact Statement for the Long- Term Management and Storage of Elemental...

  6. Interception Storage Capacities of Plants Used in Vegetated Stormwater Management Features

    NASA Astrophysics Data System (ADS)

    Rostad, N.; DiGiovanni, K. A.; Montalto, F. A.

    2011-12-01

    During and after rainstorms, evaporation of precipitation intercepted by canopies (interception loss) constitutes a large fraction of the evapotranspirative fluxes from vegetated surfaces. In engineered urban green spaces, interception losses could thus represent a significant component of stormwater management planning. Conventional hydrologic modeling tools typically predict interception losses using vegetation specific parameters such as interception storage capacity. However, these parameters were usually derived from experiments with trees, in forest stands, or cropped agricultural surfaces. There is very little data available on the interception storage capacities of plants typically used in urban greening programs. This paper will present the results of experiments performed under a rainfall simulator to empirically derive interception storage capacities for native plants typically incorporated into urban greening projects in New York City. A mass based method of measuring interception storage for ground cover plants is tested and compared to results obtained using other previously published methods. These laboratory derived values of interception storage capacities are compared with field data from four weighing lysimeters installed in green spaces in New York City. Relationships between vegetation characteristics and interception storage are explored, and the results used to compare the use of different species for stormwater management.

  7. Underground natural gas storage reservoir management: Phase 2. Final report, June 1, 1995--March 30, 1996

    SciTech Connect

    Ortiz, I.; Anthony, R.V.

    1996-12-31

    Gas storage operators are facing increased and more complex responsibilities for managing storage operations under Order 636 which requires unbundling of storage from other pipeline services. Low cost methods that improve the accuracy of inventory verification are needed to optimally manage this stored natural gas. Migration of injected gas out of the storage reservoir has not been well documented by industry. The first portion of this study addressed the scope of unaccounted for gas which may have been due to migration. The volume range was estimated from available databases and reported on an aggregate basis. Information on working gas, base gas, operating capacity, injection and withdrawal volumes, current and non-current revenues, gas losses, storage field demographics and reservoir types is contained among the FERC Form 2, EIA Form 191, AGA and FERC Jurisdictional databases. The key elements of this study show that gas migration can result if reservoir limits have not been properly identified, gas migration can occur in formation with extremely low permeability (0.001 md), horizontal wellbores can reduce gas migration losses and over-pressuring (unintentionally) storage reservoirs by reinjecting working gas over a shorter time period may increase gas migration effects.

  8. Data base management system configuration specification. [computer storage devices

    NASA Technical Reports Server (NTRS)

    Neiers, J. W.

    1979-01-01

    The functional requirements and the configuration of the data base management system are described. Techniques and technology which will enable more efficient and timely transfer of useful data from the sensor to the user, extraction of information by the user, and exchange of information among the users are demonstrated.

  9. Effects of construction and alignment errors on the orbit functions of the advanced photon source storage ring

    SciTech Connect

    Bizek, H.; Crosbie, E.; Lessner, E.; Teng, L.; Wirsbinski, J.

    1991-01-01

    The orbit functions for the Advanced Photon Source Storage Ring have been studied using the simulation code RACETRACK. Non-linear elements are substituted into the storage ring lattice to simulate the effects of construction and alignment errors in the quadrupole, dipole, and sextupole magnets. The effects of these errors on the orbit distortion, dispersion, and beta functions are then graphically analyzed to show the rms spread of the functions across several machines. The studies show that the most significant error is displacement of the quadrupole magnets. Further studies using a 3 bump correction routine show that these errors can be corrected to acceptable levels. 1 ref., 10 figs., 1 tab.

  10. Thermal management of the adsorption-based vessel for hydrogeneous gas storage

    NASA Astrophysics Data System (ADS)

    Vasiliev, L. L.; Kanonchik, L. E.; Babenko, V. A.

    2012-09-01

    Thermal management is a design bottleneck in the creation of rational gas storage sorption systems. Inefficient heat transfer in a sorption bed is connected with a relatively low thermal conductivity (0.1-0.5 W/(mṡK)) and an appreciable sorption heat of activated gas storage materials. This work is devoted to the development of a thermally regulated onboard system of hydrogenous gas (methane and hydrogen) storage with the use of novel carbon sorbents. A hydrogenous gas storage system based on combined gas adsorption and compression at moderate pressures (3-6 MPa) and low temperatures (from the temperature of liquid nitrogen of about 77 K to a temperature of 273 K) is suggested.

  11. Advances in the nutritional and pharmacological management of phenylketonuria

    PubMed Central

    Ney, Denise M.; Blank, Robert D.; Hansen, Karen E.

    2014-01-01

    Structural Abstract Purpose of review The purpose is to discuss advances in the nutritional and pharmacological management of phenylketonuria (PKU). Recent findings Glycomacropeptide (GMP), a whey protein produced during cheese production, is a low-phe intact protein that represents a new dietary alternative to synthetic amino acids (AAs) for people with PKU. Skeletal fragility is a long-term complication of PKU that based on murine research, appears to result from both genetic and nutritional factors. Skeletal fragility in murine PKU is attenuated with the GMP diet, compared with an AA diet, allowing greater radial bone growth. Pharmacologic therapy with tetrahydrobiopterin (BH4), acting as a molecular chaperone for phenylalanine hydroxylase, increases tolerance to dietary phe in some individuals. Large neutral AAs (LNAA) inhibit phe transport across the intestinal mucosa and blood brain barrier; LNAA are most effective for individuals unable to comply with the low-phe diet. Summary Although a low-phe synthetic AA diet remains the mainstay of PKU management, new nutritional and pharmacological treatment options offer alternative approaches to maintain lifelong low phe concentrations. GMP medical foods provide an alternative to AA formula that may improve bone health, and BH4 permits some individuals with PKU to increase tolerance to dietary phe. Further research is needed to characterize the long-term efficacy of these new approaches for PKU management. PMID:24136088

  12. Cluman: Advanced cluster management for the large-scale infrastructures

    NASA Astrophysics Data System (ADS)

    Babik, Marian; Fedorko, Ivan; Rodrigues, David

    2011-12-01

    The recent uptake of multi-core computing has produced a rapid growth of virtualisation and cloud computing services. With the increased use of the many-core processors this trend will likely accelerate and computing centres will be faced with the management of the tens of thousands of the virtual machines. Furthermore, these machines will likely be geographically distributed and need to be allocated on demand. In order to cope with such complexity we have designed and developed an advanced cluster management system that can execute administrative tasks targeting thousands of machines as well as provide an interactive high-density visualisation of the fabrics. The job management subsystem can perform complex tasks while following their progress and output and report aggregated information back to the system administrators. The visualisation subsystem can display tree maps of the infrastructure elements with data and monitoring information, thus providing a very detailed overview of the large clusters at a glance. The initial experience with development and testing of the system will be presented as well as an evaluation of its performance.

  13. Management of Leaks in Hydrogen Production, Delivery, and Storage Systems

    SciTech Connect

    Rawls, G

    2006-04-27

    A systematic approach to manage hydrogen leakage from components is presented. Methods to evaluate the quantity of hydrogen leakage and permeation from a system are provided by calculation and testing sensitivities. The following technology components of a leak management program are described: (1) Methods to evaluate hydrogen gas loss through leaks; (2) Methods to calculate opening areas of crack like defects; (3) Permeation of hydrogen through metallic piping; (4) Code requirements for acceptable flammability limits; (5) Methods to detect flammable gas; (6) Requirements for adequate ventilation in the vicinity of the hydrogen system; (7) Methods to calculate dilution air requirements for flammable gas mixtures; and (8) Concepts for reduced leakage component selection and permeation barriers.

  14. Open tools for storage and management of quantitative image data.

    PubMed

    Moore, Joshua; Allan, Chris; Burel, Jean-Marie; Loranger, Brian; MacDonald, Donald; Monk, Jonathan; Swedlow, Jason R

    2008-01-01

    The explosion in quantitative imaging has driven the need to develop tools for storing, managing, analyzing, and viewing large sets of data. In this chapter, we discuss tools we have built for storing large data sets for the lifetime of a typical research project. As part of the Open Microscopy Environment (OME) Consortium, we have built a series of open-source tools that support the manipulation and visualization of large sets of complex image data. Images from a number of proprietary file formats can be imported and then accessed from a single server running in a laboratory or imaging facility. We discuss the capabilities of the OME Server, a Perl-based data management system that is designed for large-scale analysis of image data using a web browser-based user interface. In addition, we have recently released a lighter weight Java-based OME Remote Objects Server that supports remote applications for managing and viewing image data. Together these systems provide a suite of tools for large-scale quantitative imaging that is now commonly used throughout cell and developmental biology. PMID:18155479

  15. Anisotropic mechanical behaviour of sedimentary basins inferred by advanced radar interferometry above gas storage fields

    NASA Astrophysics Data System (ADS)

    Teatini, P.; Gambolati, G.; Ferretti, A.

    2010-12-01

    Natural gas is commonly stored underground in depleted oil and gas fields to provide safe storage capacity and deliverability to market areas where production is limited, or to take advantage of seasonal price swings. In response to summer gas injection and winter gas withdrawal the reservoir expands and contracts with the overlying land that moves accordingly. Depending on the field burial depth, a few kilometres of the upper lithosphere are subject to local three-dimensional deformations with the related cyclic motion of the ground surface being both vertical and horizontal. Advanced Persistent Scatterer Interferometry (PSI) data, obtained by combining ascending and descending RADARSAT-1 images acquired from 2003 to 2008 above gas storage fields located in the sedimentary basin of the Po river plain, Italy, provide reliable measurement of these seasonal vertical ups and downs as well as horizontal displacements to and from the injection/withdrawal wells. Combination of the land surface movements together with an accurate reconstruction of the subsurface geology made available by three-dimensional seismic surveys and long-time records of fluid pore pressure within the 1000-1500 m deep reservoirs has allowed for the development of an accurate 3D poro-mechanical finite-element model of the gas injection/removal occurrence. Model calibration based on the observed cyclic motions, which are on the range of 10-15 mm and 5-10 mm in the vertical and horizontal west-east directions, respectively, helps characterize the nonlinear hysteretic geomechanical properties of the basin. First, using a basin-scale relationship between the oedometric rock compressibility cM in virgin loading conditions versus the effective intergranular stress derived from previous experimental studies, the modeling results show that the ratio s between loading and unloading-reloading cM is about 4, consistent with in-situ expansions measured by the radioactive marker technique in similar reservoirs

  16. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....52 Section 250.52 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF... Donated Foods in Contracts With Food Service Management Companies § 250.52 Storage and...

  17. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Storage and inventory management of donated foods. 250.52 Section 250.52 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES,...

  18. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Storage and inventory management of donated foods. 250.52 Section 250.52 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES,...

  19. Methods and Systems for Advanced Spaceport Information Management

    NASA Technical Reports Server (NTRS)

    Fussell, Ronald M. (Inventor); Ely, Donald W. (Inventor); Meier, Gary M. (Inventor); Halpin, Paul C. (Inventor); Meade, Phillip T. (Inventor); Jacobson, Craig A. (Inventor); Blackwell-Thompson, Charlie (Inventor)

    2007-01-01

    Advanced spaceport information management methods and systems are disclosed. In one embodiment, a method includes coupling a test system to the payload and transmitting one or more test signals that emulate an anticipated condition from the test system to the payload. One or more responsive signals are received from the payload into the test system and are analyzed to determine whether one or more of the responsive signals comprises an anomalous signal. At least one of the steps of transmitting, receiving, analyzing and determining includes transmitting at least one of the test signals and the responsive signals via a communications link from a payload processing facility to a remotely located facility. In one particular embodiment, the communications link is an Internet link from a payload processing facility to a remotely located facility (e.g. a launch facility, university, etc.).

  20. Recent advances in the diagnosis and management of cardiac amyloidosis.

    PubMed

    Sher, Taimur; Gertz, Morie A

    2014-01-01

    The heart is commonly involved in various forms of amyloidosis and cardiomyopathy is a major cause of morbidity and mortality in these patients. Diagnosis of cardiac amyloidosis is often delayed due to nonspecific presenting symptoms and failure to recognize early signs of amyloid heart disease on routine cardiac imaging. Treatment of cardiac amyloidosis depends upon the type of amyloid protein. Systemic chemotherapy with or without stem cell transplantation is used to treat immunoglobulin-related amyloidosis and liver transplantation is used for familial transthyretin amyloidosis in select patients. Clinical trials with siRNA for the treatment of transthyretin amyloid cardiomyopathies and amyloid protein stabilizers are ongoing. Prognosis depends on the type of amyloid protein with poorer outcomes noted in immunoglobulin light-chain amyloidosis. Supportive care forms the cornerstone of management and advancements in cardiac imaging and proteomics are expected to positively impact our ability to diagnose, prognosticate and treat cardiac amyloidosis. PMID:24344669

  1. Methods and systems for advanced spaceport information management

    NASA Technical Reports Server (NTRS)

    Fussell, Ronald M. (Inventor); Ely, Donald W. (Inventor); Meier, Gary M. (Inventor); Halpin, Paul C. (Inventor); Meade, Phillip T. (Inventor); Jacobson, Craig A. (Inventor); Blackwell-Thompson, Charlie (Inventor)

    2007-01-01

    Advanced spaceport information management methods and systems are disclosed. In one embodiment, a method includes coupling a test system to the payload and transmitting one or more test signals that emulate an anticipated condition from the test system to the payload. One or more responsive signals are received from the payload into the test system and are analyzed to determine whether one or more of the responsive signals comprises an anomalous signal. At least one of the steps of transmitting, receiving, analyzing and determining includes transmitting at least one of the test signals and the responsive signals via a communications link from a payload processing facility to a remotely located facility. In one particular embodiment, the communications link is an Internet link from a payload processing facility to a remotely located facility (e.g. a launch facility, university, etc.).

  2. 40 CFR Table 1 to Subpart Bbbbbb... - Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Limits, and Management Practices for Storage Tanks 1 Table 1 to Subpart BBBBBB of Part 63 Protection of... Criteria, Emission Limits, and Management Practices for Storage Tanks If you own or operate . . . Then you... the following:(a) Reduce emissions of total organic HAP or TOC by 95 weight-percent with a closed...

  3. 40 CFR Table 1 to Subpart Bbbbbb... - Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Limits, and Management Practices for Storage Tanks 1 Table 1 to Subpart BBBBBB of Part 63 Protection of... Criteria, Emission Limits, and Management Practices for Storage Tanks If you own or operate . . . Then you... the following:(a) Reduce emissions of total organic HAP or TOC by 95 weight-percent with a closed...

  4. 40 CFR Table 1 to Subpart Bbbbbb... - Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Limits, and Management Practices for Storage Tanks 1 Table 1 to Subpart BBBBBB of Part 63 Protection of... Criteria, Emission Limits, and Management Practices for Storage Tanks If you own or operate . . . Then you... the following:(a) Reduce emissions of total organic HAP or TOC by 95 weight-percent with a closed...

  5. 40 CFR Table 1 to Subpart Bbbbbb... - Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Limits, and Management Practices for Storage Tanks 1 Table 1 to Subpart BBBBBB of Part 63 Protection of... Criteria, Emission Limits, and Management Practices for Storage Tanks If you own or operate . . . Then you... the following:(a) Reduce emissions of total organic HAP or TOC by 95 weight-percent with a closed...

  6. Advanced Health Management System for the Space Shuttle Main Engine

    NASA Technical Reports Server (NTRS)

    Davidson, Matt; Stephens, John

    2004-01-01

    Boeing-Canoga Park (BCP) and NASA-Marshall Space Flight Center (NASA-MSFC) are developing an Advanced Health Management System (AHMS) for use on the Space Shuttle Main Engine (SSME) that will improve Shuttle safety by reducing the probability of catastrophic engine failures during the powered ascent phase of a Shuttle mission. This is a phased approach that consists of an upgrade to the current Space Shuttle Main Engine Controller (SSMEC) to add turbomachinery synchronous vibration protection and addition of a separate Health Management Computer (HMC) that will utilize advanced algorithms to detect and mitigate predefined engine anomalies. The purpose of the Shuttle AHMS is twofold; one is to increase the probability of successfully placing the Orbiter into the intended orbit, and the other is to increase the probability of being able to safely execute an abort of a Space Transportation System (STS) launch. Both objectives are achieved by increasing the useful work envelope of a Space Shuttle Main Engine after it has developed anomalous performance during launch and the ascent phase of the mission. This increase in work envelope will be the result of two new anomaly mitigation options, in addition to existing engine shutdown, that were previously unavailable. The added anomaly mitigation options include engine throttle-down and performance correction (adjustment of engine oxidizer to fuel ratio), as well as enhanced sensor disqualification capability. The HMC is intended to provide the computing power necessary to diagnose selected anomalous engine behaviors and for making recommendations to the engine controller for anomaly mitigation. Independent auditors have assessed the reduction in Shuttle ascent risk to be on the order of 40% with the combined system and a three times improvement in mission success.

  7. Advances in the rehabilitation management of acute spinal cord injury.

    PubMed

    Ditunno, John F; Cardenas, Diana D; Formal, Christopher; Dalal, Kevin

    2012-01-01

    Aggressive assessment and management of the secondary complications in the hours and days following spinal cord injury (SCI) leads to restoration of function in patients through intervention by a team of rehabilitation professionals. The recent certification of SCI physicians, newly validated assessments of impairment and function measures, and international databases agreed upon by SCI experts should lead to documentation of improved rehabilitation care. This chapter highlights recent advances in assessment and treatment based on evidence-based classification of literature reviews and expert opinion in the acute phase of SCI. A number of these reviews are the product of the Consortium for Spinal Cord Medicine, which offers clinical practice guidelines for healthcare professionals. Recognition of and early intervention for problems such as bradycardia, orthostatic hypotension, deep vein thrombosis/pulmonary embolism, and early ventilatory failure will be addressed although other chapters may discuss some issues in greater detail. Early assessment and intervention for neurogenic bladder and bowel function has proven effective in the prevention of renal failure and uncontrolled incontinence. Attention to overuse and disuse with training and advanced technology such as functional electrical stimulation have reduced pain and disability associated with upper extremity deterioration and improved physical fitness. Topics such as chronic pain, spasticity, sexual dysfunction, and pressure sores will be covered in more detail in additional chapters. However, the comprehensive and integrated rehabilitation by specialized SCI teams of physicians, nurses, therapists, social workers, and psychologists immediately following SCI has become the standard of care throughout the world. PMID:23098713

  8. Cryogenic Thermal Management Advances during the CRYOTOOL Program

    NASA Astrophysics Data System (ADS)

    Bugby, D.; Stouffer, C.; Garzon, J.; Beres, M.; Gilchrist, A.; Roberts, T.; Davis, T.

    2006-04-01

    This paper describes the cryogenic thermal management advances made during the AFRL-sponsored CRYOTOOL program. Advances occurred as a result of conducting four technology development tasks: (1) development of a differential thermal expansion cryogenic thermal switch (DTE-CTSW) made with high purity Al end-pieces and an Ultem support rod; (2) carrying out of a dual DTE-CTSW/dual cryocooler performance test to quantify CTSW benefits in a redundant cryocooler system; (3) development of a miniaturized cryogenic loop heat pipe (mini-CLHP) that combines flex link, conduction bar, and CTSW functionalities; and (4) development of an across-gimbal cryogenic thermal transport system (GCTTS) with large diameter transport line coils for optics cooling. The results are as follows. The DTE-CTSW achieved an ON conductance of 2-3.6 W/K (from 35-90 K) and an OFF resistance of 1100-2300 K/W (300-230 K warm end). The redundant cryocooler test showed modest parasitic heat leak savings when dual DTE-CTSWs were used versus when they were not used. The mini-CLHP, using neon as the working fluid, transported 2.5 W at 35 K, achieved an OFF resistance of 1555 K/W, and had cross/axial flexibilities of 100-450 N/m. Lastly, GCTTS, using nitrogen as the working fluid, transported 20 W at 100 K in a flat configuration. Additional work is needed to verify GCTTS operation in an elevated orientation.

  9. Masters Study in Advanced Energy and Fuels Management

    SciTech Connect

    Mondal, Kanchan

    2014-12-08

    There are currently three key drivers for the US energy sector a) increasing energy demand and b) environmental stewardship in energy production for sustainability and c) general public and governmental desire for domestic resources. These drivers are also true for energy nation globally. As a result, this sector is rapidly diversifying to alternate sources that would supplement or replace fossil fuels. These changes have created a need for a highly trained workforce with a the understanding of both conventional and emerging energy resources and technology to lead and facilitate the reinvention of the US energy production, rational deployment of alternate energy technologies based on scientific and business criteria while invigorating the overall economy. In addition, the current trends focus on the the need of Science, Technology, Engineering and Math (STEM) graduate education to move beyond academia and be more responsive to the workforce needs of businesses and the industry. The SIUC PSM in Advanced Energy and Fuels Management (AEFM) program was developed in response to the industries stated need for employees who combine technical competencies and workforce skills similar to all PSM degree programs. The SIUC AEFM program was designed to provide the STEM graduates with advanced technical training in energy resources and technology while simultaneously equipping them with the business management skills required by professional employers in the energy sector. Technical training include core skills in energy resources, technology and management for both conventional and emerging energy technologies. Business skills training include financial, personnel and project management. A capstone internship is also built into the program to train students such that they are acclimatized to the real world scenarios in research laboratories, in energy companies and in government agencies. The current curriculum in the SIUC AEFM will help fill the need for training both recent

  10. Tools for advance directives. American Health Information Management Association.

    PubMed

    Schraffenberger, L A

    1992-02-01

    This issue of the Journal of AHIMA contains a Position Statement on advance directives. Here we have included several "tools" or helpful documents to support your organization's ongoing education regarding advance directives. First, we offer a "Sample Policy and Procedure" addressing the administrative process of advance directives. This sample policy was adapted from a policy shared by Jean Clark, RRA, operations director with Roper Hospital in Charleston, SC, and a director on the AHIMA Board of Directors. Do not automatically accept this policy and procedure for your organization. Instead, the health information management professional could use this sample to write your organization's own, specific policy and procedures that are consistent with your state's law and legal counsel's advice. The second article, "Advance Directives and the New Joint Commission Requirements," compares 1992 Joint Commission standards for Patient Rights and The Patient Self-Determination Act requirements. Selected sections from the Joint Commission chapter on Patient Rights are highlighted and comments added that contrast it with the act. "Common Questions and Answers Related to Advance Directives" is the third tool we offer. These questions and answers may be used for a patient education brochure or staff inservice education program outline. Again, information specific to your own state needs to be added. The fourth tool we offer is miniature "Sample Slides" or overhead transparency copy that can be enlarged and used for a presentation on the basics of advance directives for a community group for staff education. We thank Dee McLane, RRA, director, Medical Information Services at Self Memorial Hospital in Greenwood, SC, who developed these slides for presentations conducted at her hospital. We also thank Jeri Whitworth, RRA, who produced the graphics on these slides. Whitworth is a first year director on the AHIMA Board of Directors this year. Again you can use as is or consider

  11. Hydrogen as a fuel for today and tomorrow: expectations for advanced hydrogen storage materials/systems research.

    PubMed

    Hirose, Katsuhiko

    2011-01-01

    History shows that the evolution of vehicles is promoted by several environmental restraints very similar to the evolution of life. The latest environmental strain is sustainability. Transport vehicles are now facing again the need to advance to use sustainable fuels such as hydrogen. Hydrogen fuel cell vehicles are being prepared for commercialization in 2015. Despite intensive research by the world's scientists and engineers and recent advances in our understanding of hydrogen behavior in materials, the only engineering phase technology which will be available for 2015 is high pressure storage. Thus industry has decided to implement the high pressure tank storage system. However the necessity of smart hydrogen storage is not decreasing but rather increasing because high market penetration of hydrogen fuel cell vehicles is expected from around 2025 onward. In order to bring more vehicles onto the market, cheaper and more compact hydrogen storage is inevitable. The year 2025 seems a long way away but considering the field tests and large scale preparation required, there is little time available for research. Finding smart materials within the next 5 years is very important to the success of fuel cells towards a low carbon sustainable world. PMID:22455059

  12. Extending DIRAC File Management with Erasure-Coding for efficient storage.

    NASA Astrophysics Data System (ADS)

    Cadellin Skipsey, Samuel; Todev, Paulin; Britton, David; Crooks, David; Roy, Gareth

    2015-12-01

    The state of the art in Grid style data management is to achieve increased resilience of data via multiple complete replicas of data files across multiple storage endpoints. While this is effective, it is not the most space-efficient approach to resilience, especially when the reliability of individual storage endpoints is sufficiently high that only a few will be inactive at any point in time. We report on work performed as part of GridPP[1], extending the Dirac File Catalogue and file management interface to allow the placement of erasure-coded files: each file distributed as N identically-sized chunks of data striped across a vector of storage endpoints, encoded such that any M chunks can be lost and the original file can be reconstructed. The tools developed are transparent to the user, and, as well as allowing up and downloading of data to Grid storage, also provide the possibility of parallelising access across all of the distributed chunks at once, improving data transfer and IO performance. We expect this approach to be of most interest to smaller VOs, who have tighter bounds on the storage available to them, but larger (WLCG) VOs may be interested as their total data increases during Run 2. We provide an analysis of the costs and benefits of the approach, along with future development and implementation plans in this area. In general, overheads for multiple file transfers provide the largest issue for competitiveness of this approach at present.

  13. Monitoring plan for routine organic air emissions at the Radioactive Waste Management Complex Waste Storage Facilities

    SciTech Connect

    Galloway, K.J.; Jolley, J.G.

    1994-06-01

    This monitoring plan provides the information necessary to perform routine organic air emissions monitoring at the Waste Storage Facilities located at the Transuranic Storage Area of the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory. The Waste Storage Facilities include both the Type I and II Waste Storage Modules. The plan implements a dual method approach where two dissimilar analytical methodologies, Open-Path Fourier Transform Infrared Spectroscopy (OP-FTIR) and ancillary SUMMA{reg_sign} canister sampling, following the US Environmental Protection Agency (EPA) analytical method TO-14, will be used to provide qualitative and quantitative volatile organic concentration data. The Open-Path Fourier Transform Infrared Spectroscopy will provide in situ, real time monitoring of volatile organic compound concentrations in the ambient air of the Waste Storage Facilities. To supplement the OP-FTIR data, air samples will be collected using SUMMA{reg_sign}, passivated, stainless steel canisters, following the EPA Method TO-14. These samples will be analyzed for volatile organic compounds with gas chromatograph/mass spectrometry analysis. The sampling strategy, procedures, and schedules are included in this monitoring plan. The development of this monitoring plan is driven by regulatory compliance to the Resource Conservation and Recovery Act, State of Idaho Toxic Air Pollutant increments, Occupational Safety and Health Administration. The various state and federal regulations address the characterization of the volatile organic compounds and the resultant ambient air emissions that may originate from facilities involved in industrial production and/or waste management activities.

  14. Selective Mastectomy in the Management of Locally Advanced Breast Cancer

    SciTech Connect

    Ahern, Verity . E-mail: verity.ahern@swahs.healthnsw.gov.au; Boyages, John; Gebski, Val M. Stat; Moon, Dominic; Wilcken, Nicholas

    2007-07-15

    Purpose: To evaluate local control for patients with locally advanced noninflammatory breast cancer (LABC) managed by selective mastectomy. Methods and Materials: Between 1979 and 1996, 176 patients with LABC were prospectively managed by chemotherapy (CT)-irradiation (RT)-CT without routine mastectomy. All surviving patients were followed for a minimum of 5 years. Results: A total of 132 patients (75%) had a T4 tumor and 22 (12.5%) supraclavicular nodal disease. The clinical complete response rate was 91% (160/176), which included 13 patients who underwent mastectomy and 2 an iridium wire implant. The first site of failure was local for 43 patients (breast {+-} axilla for 38); 27 of these patients underwent salvage mastectomy and 11 did not for an overall mastectomy rate of 23% (40/176). If all 176 patients had undergone routine mastectomy (136 extra mastectomies), 11 additional patients may have avoided an unsalvageable first local relapse. The others would have either have not had a local relapse or would have suffered local relapse after distant disease. No tumor or treatment related factor was found to predict local disease at death. Median disease-free and overall survival for all patients was 26 and 52 months, respectively. Conclusions: Selective mastectomy in LABC may not jeopardize local control or survival.

  15. Pre-injection brine production for managing pressure in compartmentalized CO₂ storage reservoirs

    SciTech Connect

    Buscheck, Thomas A.; White, Joshua A.; Chen, Mingjie; Sun, Yunwei; Hao, Yue; Aines, Roger D.; Bourcier, William L.; Bielicki, Jeffrey M.

    2014-12-31

    We present a reservoir management approach for geologic CO₂ storage that combines CO₂ injection with brine extraction. In our approach,dual-mode wells are initially used to extract formation brine and subsequently used to inject CO₂. These wells can also be used to monitor the subsurface during pre-injection brine extraction so that key data is acquired and analyzed prior to CO₂ injection. The relationship between pressure drawdown during pre-injection brine extraction and pressure buildup during CO₂ injection directly informs reservoir managers about CO₂ storage capacity. These data facilitate proactive reservoir management, and thus reduce costs and risks. The brine may be used directly as make-up brine for nearby reservoir operations; it can also be desalinated and/or treated for a variety of beneficial uses.

  16. Pre-injection brine production for managing pressure in compartmentalized CO₂ storage reservoirs

    DOE PAGESBeta

    Buscheck, Thomas A.; White, Joshua A.; Chen, Mingjie; Sun, Yunwei; Hao, Yue; Aines, Roger D.; Bourcier, William L.; Bielicki, Jeffrey M.

    2014-12-31

    We present a reservoir management approach for geologic CO₂ storage that combines CO₂ injection with brine extraction. In our approach,dual-mode wells are initially used to extract formation brine and subsequently used to inject CO₂. These wells can also be used to monitor the subsurface during pre-injection brine extraction so that key data is acquired and analyzed prior to CO₂ injection. The relationship between pressure drawdown during pre-injection brine extraction and pressure buildup during CO₂ injection directly informs reservoir managers about CO₂ storage capacity. These data facilitate proactive reservoir management, and thus reduce costs and risks. The brine may be usedmore » directly as make-up brine for nearby reservoir operations; it can also be desalinated and/or treated for a variety of beneficial uses.« less

  17. Structured storage in ATLAS Distributed Data Management: use cases and experiences

    NASA Astrophysics Data System (ADS)

    Lassnig, Mario; Garonne, Vincent; Molfetas, Angelos; Beermann, Thomas; Dimitrov, Gancho; Canali, Luca; Zang, Donal; Azzurra Chinzer, Lisa

    2012-12-01

    The distributed data management system of the high-energy physics experiment ATLAS has a critical dependency on the Oracle Relational Database Management System. Recently however, the increased appearance of data warehouselike workload in the experiment has put considerable and increasing strain on the Oracle database. In particular, the analysis of archived data, and the aggregation of data for summary purposes has been especially demanding. For this reason, structured storage systems were evaluated to offload the Oracle database, and to handle processing of data in a non-transactional way. This includes distributed file systems like HDFS that support parallel execution of computational tasks on distributed data, as well as non-relational databases like HBase, Cassandra, or MongoDB. In this paper, the most important analysis and aggregation use cases of the data management system are presented, and how structured storage systems were established to process them.

  18. Advanced Simulation Capability for Environmental Management (ASCEM): Early Site Demonstration

    SciTech Connect

    Meza, Juan; Hubbard, Susan; Freshley, Mark D.; Gorton, Ian; Moulton, David; Denham, Miles E.

    2011-03-07

    The U.S. Department of Energy Office of Environmental Management, Technology Innovation and Development (EM-32), is supporting development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is a state-of-the-art scientific tool and approach for understanding and predicting contaminant fate and transport in natural and engineered systems. The modular and open source high performance computing tool will facilitate integrated approaches to modeling and site characterization that enable robust and standardized assessments of performance and risk for EM cleanup and closure activities. As part of the initial development process, a series of demonstrations were defined to test ASCEM components and provide feedback to developers, engage end users in applications, and lead to an outcome that would benefit the sites. The demonstration was implemented for a sub-region of the Savannah River Site General Separations Area that includes the F-Area Seepage Basins. The physical domain included the unsaturated and saturated zones in the vicinity of the seepage basins and Fourmile Branch, using an unstructured mesh fit to the hydrostratigraphy and topography of the site. The calculations modeled variably saturated flow and the resulting flow field was used in simulations of the advection of non-reactive species and the reactive-transport of uranium. As part of the demonstrations, a new set of data management, visualization, and uncertainty quantification tools were developed to analyze simulation results and existing site data. These new tools can be used to provide summary statistics, including information on which simulation parameters were most important in the prediction of uncertainty and to visualize the relationships between model input and output.

  19. Advanced Simulation Capability for Environmental Management: Development and Demonstrations - 12532

    SciTech Connect

    Freshley, Mark D.; Freedman, Vicky; Gorton, Ian; Hubbard, Susan S.; Moulton, J. David; Dixon, Paul

    2012-07-01

    The U.S. Department of Energy Office of Environmental Management (EM), Technology Innovation and Development is supporting development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is a state-of-the-art scientific tool and approach for understanding and predicting contaminant fate and transport in natural and engineered systems. The modular and open source high-performance computing tool facilitates integrated approaches to modeling and site characterization that enable robust and standardized assessments of performance and risk for EM cleanup and closure activities. The ASCEM project continues to make significant progress in development of capabilities, which are organized into Platform and Integrated Tool-sets and a High-Performance Computing Multi-process Simulator. The Platform capabilities target a level of functionality to allow end-to-end model development, starting with definition of the conceptual model and management of data for model input. The High-Performance Computing capabilities target increased functionality of process model representations, tool-sets for interaction with Platform, and verification and model confidence testing. The new capabilities are demonstrated through working groups, including one focused on the Hanford Site Deep Vadose Zone. The ASCEM program focused on planning during the first year and executing a prototype tool-set for an early demonstration of individual components. Subsequently, ASCEM has focused on developing and demonstrating an integrated set of capabilities, making progress toward a version of the capabilities that can be used to engage end users. Demonstration of capabilities continues to be implemented through working groups. Three different working groups, one focused on EM problems in the deep vadose zone, another investigating attenuation mechanisms for metals and radionuclides, and a third focusing on waste tank performance assessment, continue to make progress. The project

  20. Modular tube/plate-based sample management: a business model optimized for scalable storage and processing.

    PubMed

    Fillers, W Steven

    2004-12-01

    Modular approaches to sample management allow staged implementation and progressive expansion of libraries within existing laboratory space. A completely integrated, inert atmosphere system for the storage and processing of a variety of microplate and microtube formats is currently available as an integrated series of individual modules. Liquid handling for reformatting and replication into microplates, plus high-capacity cherry picking, can be performed within the inert environmental envelope to maximize compound integrity. Complete process automation provides ondemand access to samples and improved process control. Expansion of such a system provides a low-risk tactic for implementing a large-scale storage and processing system. PMID:15674027

  1. Storage management influences greenhouse gas emissions from biosolids.

    PubMed

    Majumder, Ramaprasad; Livesley, Stephen J; Gregory, David; Arndt, Stefan K

    2015-03-15

    Biosolids produced by wastewater treatment plants are often stored in stockpiles and can be a significant source of greenhouse gases (GHG). Growing trees in shallow stockpiled biosolids may remove nutrients, keep the biosolids drier and offset GHG emissions through C sequestration. We directly measured methane (CH4), carbon dioxide (CO2) and nitrous oxide (N2O) flux from a large biosolid stockpile and two shallow stockpiles, one planted with Salix reichardtii (willow) trees, from December 2009 to January 2011. All stockpiles emitted large annual amounts of GHG ranging from 38 kg CO2-e Mg(-1) dry biosolid for the large stockpile, to 65 kg CO2-e Mg(-1) for the unplanted shallow stockpile, probably due to the greater surface area to volume ratio. GHG emissions were dominated by N2O and CO2 whilst CH4 emissions were negligible (<2%) from the large stockpile and the shallow stockpiles were actually a CH4 sink. Annual willow tree growth was 12 Mg dry biomass ha(-1), but this only offset 8% of the GHG emissions from the shallow planted stockpile. Our data highlight that biosolid stockpiles are significant sources for GHG emissions but alternate management options such as shallow stockpiles or planting for biomass production will not lead to GHG emission reductions. PMID:25585149

  2. 41 CFR 102-80.40 - What are Federal agencies' responsibilities concerning the management of underground storage tanks?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Safety and Environmental Management Underground Storage Tanks § 102-80.40 What are Federal agencies' responsibilities... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What are...

  3. 41 CFR 102-80.40 - What are Federal agencies' responsibilities concerning the management of underground storage tanks?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 80-SAFETY AND ENVIRONMENTAL MANAGEMENT Safety and Environmental Management Underground Storage Tanks § 102-80.40 What are Federal agencies' responsibilities... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are...

  4. Advanced Health Management Algorithms for Crew Exploration Applications

    NASA Technical Reports Server (NTRS)

    Davidson, Matt; Stephens, John; Jones, Judit

    2005-01-01

    Achieving the goals of the President's Vision for Exploration will require new and innovative ways to achieve reliability increases of key systems and sub-systems. The most prominent approach used in current systems is to maintain hardware redundancy. This imposes constraints to the system and utilizes weight that could be used for payload for extended lunar, Martian, or other deep space missions. A technique to improve reliability while reducing the system weight and constraints is through the use of an Advanced Health Management System (AHMS). This system contains diagnostic algorithms and decision logic to mitigate or minimize the impact of system anomalies on propulsion system performance throughout the powered flight regime. The purposes of the AHMS are to increase the probability of successfully placing the vehicle into the intended orbit (Earth, Lunar, or Martian escape trajectory), increase the probability of being able to safely execute an abort after it has developed anomalous performance during launch or ascent phases of the mission, and to minimize or mitigate anomalies during the cruise portion of the mission. This is accomplished by improving the knowledge of the state of the propulsion system operation at any given turbomachinery vibration protection logic and an overall system analysis algorithm that utilizes an underlying physical model and a wide array of engine system operational parameters to detect and mitigate predefined engine anomalies. These algorithms are generic enough to be utilized on any propulsion system yet can be easily tailored to each application by changing input data and engine specific parameters. The key to the advancement of such a system is the verification of the algorithms. These algorithms will be validated through the use of a database of nominal and anomalous performance from a large propulsion system where data exists for catastrophic and noncatastrophic propulsion sytem failures.

  5. Recent advances in the understanding and management of delayed puberty.

    PubMed

    Wei, Christina; Crowne, Elizabeth Clare

    2016-05-01

    Delayed puberty, especially in boys, is a common presentation in paediatrics. Recent advances have improved our understanding of the neuroendocrine, genetic and environmental factors controlling pubertal development, and hence inform the pathophysiology of delayed puberty. The discovery of kisspeptin signalling through its receptor identified neuroendocrine mechanisms controlling the gonadotrophin-releasing hormone (GnRH) pulse generator at the onset of puberty. Genetic mechanisms from single gene mutations to single nucleotide polymorphism associated with delayed puberty are being identified. Environmental factors, including nutritional factors and endocrine disruptors, have also been implicated in changes in secular trends and abnormal timing of puberty. Despite these advances, the key clinical question is to distinguish delayed puberty associated with an underlying pathology or hypogonadism from constitutional delay in growth and puberty, which remains challenging as biochemical tests are not always discriminatory. The diagnostic accuracies of newer investigations, including 36-hour luteinising hormone releasing hormone (LHRH) tests, GnRH-agonist tests, antimullerian hormone and inhibin-B, require further evaluation. Sex hormone replacement remains the main available treatment for delayed puberty, the choice of which is largely dictated by clinical practice and availability of the various sex steroid preparations. Spontaneous reversal of hypogonadism has been reported in boys with idiopathic hypogonadotrophic hypogonadism after a period of sex steroid treatment, highlighting the importance of reassessment at the end of pubertal induction. Novel therapies with a more physiological basis such as gonadotrophins or kisspeptin-agonist are being investigated for the management of hypogonadotrophic hypogonadism. Careful clinical assessment and appreciation of the normal physiology remain the key approach to patients with delayed puberty. PMID:26353794

  6. Design of System Architecture and Thermal Management Components for an Underwater Energy Storage Facility

    NASA Astrophysics Data System (ADS)

    Cheung, Brian C.

    The electricity industry is currently experiencing a significant paradigm shift in managing electrical resources. With the onset of aging infrastructure and growing power demands, and the influx of intermittent renewable energy generation, grid system operators are looking towards energy storage as a solution for mitigating industry challenges. An emerging storage solution is underwater compressed air energy storage (UWCAES), where air compressors and turbo-expanders are used to convert electricity to and from compressed air stored in submerged accumulators. This work presents three papers that collectively focus on the design and optimization of an UWCAES system. In the first paper, the field performance of a distensible air accumulator is studied for application in UWCAES systems. It is followed by a paper that analyzed the energetic and exergetic performance of a theoretical UWCAES system. The final paper presents a multi-objective UWCAES optimization model utilizing a genetic algorithm to determine optimum system configurations.

  7. SAM-FS: LSC's New Solaris-Based Storage Management Product

    NASA Technical Reports Server (NTRS)

    Angell, Kent

    1996-01-01

    SAM-FS is a full featured hierarchical storage management (HSM) device that operates as a file system on Solaris-based machines. The SAM-FS file system provides the user with all of the standard UNIX system utilities and calls, and adds some new commands, i.e. archive, release, stage, sls, sfind, and a family of maintenance commands. The system also offers enhancements such as high performance virtual disk read and write, control of the disk through an extent array, and the ability to dynamically allocate block size. SAM-FS provides 'archive sets' which are groupings of data to be copied to secondary storage. In practice, as soon as a file is written to disk, SAM-FS will make copies onto secondary media. SAM-FS is a scalable storage management system. The system can manage millions of files per system, though this is limited today by the speed of UNIX and its utilities. In the future, a new search algorithm will be implemented that will remove logical and performance restrictions on the number of files managed.

  8. Recovery Act. Advanced Load Identification and Management for Buildings

    SciTech Connect

    Yang, Yi; Casey, Patrick; Du, Liang; He, Dawei

    2014-02-12

    , in particular, advanced power strips (APSs) was studied. The project evaluated the market potential for Smart Power Strips (SPSs) with load identification and the likely impact of a load identification feature on APS adoption and effectiveness. The project also identified other success factors required for widespread APS adoption and market acceptance. Even though the developed technology is applicable for both residential and commercial buildings, this project is focused on effective plug-in load control and management for commercial buildings, accomplished through effective load identification. The project has completed Smart Receptacle (SR) prototype development with integration of Load ID, Control/Management, WiFi communication, and Web Service. Twenty SR units were built, tested, and demonstrated in the Eaton lab; eight SR units were tested in the National Renewable Energy Lab (NREL) for one-month of field testing. Load ID algorithm testing for extended load sets was conducted within the Eaton facility and at local university campuses. This report is to summarize the major achievements, activities, and outcomes under the execution of the project.

  9. Comparison of advanced thermal and electrical storage for parabolic dish solar thermal power systems

    NASA Technical Reports Server (NTRS)

    Fujita, T.; Birur, G. C.; Schredder, J. M.; Bowyer, J. M.; Awaya, H. I.

    1982-01-01

    Parabolic dish solar concentrator cluster concepts are explored, with attention given to thermal storage systems coupled to Stirling and Brayton cycle power conversion devices. Sensible heat storage involving molten salt (NaOH), liquid sodium, and solid cordierite bricks are considered for 1500 F thermal storage systems. Latent heat storage with NaF-MgF2 phase change materials are explored in terms of passive, active, and direct contact designs. Comparisons are made of the effectiveness of thermal storage relative to redox, Na-S, Zn-Cl, and Zn-Br battery storage systems. Molten lead trickling down through a phase change eutectic, the NaF-MgF2, formed the direct contact system. Heat transport in all systems is effected through Inconel pipes. Using a cost goal of 120-150 mills/kWh as the controlling parameter, sensible heat systems with molten salts transport with either Stirling or Brayton engines, or latent heat systems with Stirling engines, and latent heat-Brayton engine with direct contact were favored in the analyses. Battery storage systems, however, offered the most flexibility of applications.

  10. ENTERPRISE SRS: LEVERAGING ONGOING OPERATIONS TO ADVANCE RADIOACTIVE WASTE MANAGEMENT TECHNOLOGIES

    SciTech Connect

    Murray, A.; Wilmarth, W.; Marra, J.; Mcguire, P.; Wheeler, V.

    2013-05-16

    continue to accomplish DOE’s critical nuclear material missions (e.g., processing in H-Canyon and plutonium storage in K-Area). These demonstrations can be accomplished in a more cost-effective manner through the use of existing facilities in conjunction with ongoing missions. Essentially, the R&D program would not need to pay the full operational cost of a facility, just the incremental cost of performing the demonstration. Current Center activities have been focused on integrating advanced safeguards monitoring technology demonstrations into the SRS H-Canyon and advanced location technology demonstrations into K-Area Materials Storage. These demonstrations are providing valuable information to researchers and program owners. In addition these demonstrations are providing the Center with an improved protocol for demonstration management that can be exercised across the entire SRS (and to offsite venues) to ensure that future demonstrations are done efficiently and provide an opportunity to use these unique assets for multiple purposes involving national laboratories, academia, and commercial entities. Key among the envisioned future use of SRS assets is the demonstration of new radioactive waste management technologies critical for advancing the mission needs of the DOE-EM program offices in their efforts to cleanup 107 sites across the United States. Of particular interest is the demonstration of separations technologies in H-Canyon. Given the modular design of H-Canyon, those demonstrations would be accomplished using a process frame. The demonstration equipment would be installed on the process frame and that frame would then be positioned into an H-Canyon cell so that the demonstration is performed in a radiological environment involving prototypic nuclear materials.

  11. Advanced Information Management Services in SCOOP, an IOOS Testbed

    NASA Astrophysics Data System (ADS)

    Conover, H.; Keiser, K.; Graves, S.; Beaumont, B.; Drewry, M.; Maskey, M.

    2006-05-01

    The Integrated Ocean Observing System (IOOS) represents a national initiative to create a new system for collecting and disseminating information about the oceans. The system will support a variety of practical applications, along with enabling research. A key partner in IOOS design and development, the Southeastern Universities Research Association (SURA) is a consortium of over sixty universities across the US. Building on the capabilities of its member universities, SURA seeks to develop a network of sensors and linked computers as part of the SURA Coastal Ocean Observing and Prediction (SCOOP) program, fully integrating several observing systems in the southern US. SCOOP's goal is to create a scalable, modular prediction system for storm surge and wind waves. The system will enable a "transition to operations" of cutting-edge modeling activities from the research community. This network will provide data in real-time and at high speed, for more reliable, accurate and timely information to help guide effective coastal stewardship, plan for extreme events, facilitate safe maritime operations, and support coastal security. The University of Alabama in Huntsville is developing a suite of advanced technologies to provide core data and information management services for SCOOP. This Scientific Catalog for Open Resource Exchange (SCORE) is built on UAH's information technology research for a variety of projects, including the NASA- funded Global Hydrology Resource Center and DISCOVER REASoN projects, NSF-funded Linked Environments for Atmospheric Discovery (LEAD) large Information Technology Research project, as well as for SCOOP, which is funded by NOAA and ONR. Key technologies include an extensible database schema and ontology for the target science domain. Web services provide low level catalog access, while an integrated search capability includes semantic searching and browsing, with the potential for specialized, innovative interfaces for specific research

  12. Implementation of system intelligence in a 3-tier telemedicine/PACS hierarchical storage management system

    NASA Astrophysics Data System (ADS)

    Chao, Woodrew; Ho, Bruce K. T.; Chao, John T.; Sadri, Reza M.; Huang, Lu J.; Taira, Ricky K.

    1995-05-01

    Our tele-medicine/PACS archive system is based on a three-tier distributed hierarchical architecture, including magnetic disk farms, optical jukebox, and tape jukebox sub-systems. The hierarchical storage management (HSM) architecture, built around a low cost high performance platform [personal computers (PC) and Microsoft Windows NT], presents a very scaleable and distributed solution ideal for meeting the needs of client/server environments such as tele-medicine, tele-radiology, and PACS. These image based systems typically require storage capacities mirroring those of film based technology (multi-terabyte with 10+ years storage) and patient data retrieval times at near on-line performance as demanded by radiologists. With the scaleable architecture, storage requirements can be easily configured to meet the needs of the small clinic (multi-gigabyte) to those of a major hospital (multi-terabyte). The patient data retrieval performance requirement was achieved by employing system intelligence to manage migration and caching of archived data. Relevant information from HIS/RIS triggers prefetching of data whenever possible based on simple rules. System intelligence embedded in the migration manger allows the clustering of patient data onto a single tape during data migration from optical to tape medium. Clustering of patient data on the same tape eliminates multiple tape loading and associated seek time during patient data retrieval. Optimal tape performance can then be achieved by utilizing the tape drives high performance data streaming capabilities thereby reducing typical data retrieval delays associated with streaming tape devices.

  13. 41 CFR 302-9.11 - May I receive an advance of funds for transportation and emergency storage of my POV?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of funds for transportation and emergency storage of my POV? 302-9.11 Section 302-9.11 Public... General Rules § 302-9.11 May I receive an advance of funds for transportation and emergency storage of my... storage of your POV. Effective Date Note: By FTR Amdt. 2011-01, 76 FR 18342, Apr. 1, 2011, § 302-9.11...

  14. Storage resource manager version 2.2: design, implementation, and testing experience

    NASA Astrophysics Data System (ADS)

    Donno, F.; Abadie, L.; Badino, P.; Baud, J.-P.; Corso, E.; Witt, S. D.; Fuhrmann, P.; Gu, J.; Koblitz, B.; Lemaitre, S.; Litmaath, M.; Litvintsev, D.; Presti, G. L.; Magnoni, L.; McCance, G.; Mkrtchan, T.; Mollon, R.; Natarajan, V.; Perelmutov, T.; Petravick, D.; Shoshani, A.; Sim, A.; Smith, D.; Tedesco, P.; Zappi, R.

    2008-07-01

    Storage Services are crucial components of the Worldwide LHC Computing Grid Infrastructure spanning more than 200 sites and serving computing and storage resources to the High Energy Physics LHC communities. Up to tens of Petabytes of data are collected every year by the four LHC experiments at CERN. To process these large data volumes it is important to establish a protocol and a very efficient interface to the various storage solutions adopted by the WLCG sites. In this work we report on the experience acquired during the definition of the Storage Resource Manager v2.2 protocol. In particular, we focus on the study performed to enhance the interface and make it suitable for use by the WLCG communities. At the moment 5 different storage solutions implement the SRM v2.2 interface: BeStMan (LBNL), CASTOR (CERN and RAL), dCache (DESY and FNAL), DPM (CERN), and StoRM (INFN and ICTP). After a detailed inside review of the protocol, various test suites have been written identifying the most effective set of tests: the S2 test suite from CERN and the SRM-Tester test suite from LBNL. Such test suites have helped verifying the consistency and coherence of the proposed protocol and validating existing implementations. We conclude our work describing the results achieved.

  15. Advances in knowledge management for pharmaceutical research and development.

    PubMed

    Torr-Brown, Sheryl

    2005-05-01

    There are two assumptions that are taken for granted in the pharmaceutical industry today. Firstly, that we can generate an unprecedented amount of drug-related information along the research and development (R&D) pipeline, and secondly, that researchers are more connected to each other than they have ever been, owing to the internet revolution of the past 15 years or so. Both of these aspects of the modern pharmaceutical company have brought many benefits to the business. However, the pharmaceutical industry is currently under fire due to allegations of decreased productivity despite significant investments in R&D, which if left to continue at the present pace, will reach almost US 60 billion dollars by 2006. This article explores the role of knowledge in the industry and reviews recent developments and emerging opportunities in the field of knowledge management (KM) as it applies to pharmaceutical R&D. It is argued that systematic KM will be increasingly necessary to optimize the value of preceding advances in high-throughput approaches to R&D, and to fully realize the anticipated increase in productivity. The application of KM principles and practices to the business can highlight opportunities for balancing the current reliance on blockbuster drugs with a more patient-centric focus on human health, which is now becoming possible. PMID:15892246

  16. Recent advances in diagnosis and management of Mycotic Keratitis

    PubMed Central

    Maharana, Prafulla K; Sharma, Namrata; Nagpal, Ritu; Jhanji, Vishal; Das, Sujata; Vajpayee, Rasik B

    2016-01-01

    Mycotic keratitis is a major cause of corneal blindness, especially in tropical and subtropical countries. The prognosis is markedly worse compared to bacterial keratitis. Delayed diagnosis and scarcity of effective antifungal agents are the major factors for poor outcome. Over the last decade, considerable progress has been made to rapidly diagnose cases with mycotic keratitis and increase the efficacy of treatment. This review article discusses the recent advances in diagnosis and management of mycotic keratitis with a brief discussion on rare and emerging organisms. A MEDLINE search was carried out for articles in English language, with the keywords, mycotic keratitis, fungal keratitis, emerging or atypical fungal pathogens in mycotic keratitis, investigations in mycotic keratitis, polymerase chain reaction in mycotic keratitis, confocal microscopy, treatment of mycotic keratitis, newer therapy for mycotic keratitis. All relevant articles were included in this review. Considering the limited studies available on newer diagnostic and therapeutic modalities in mycotic keratitis, case series as well as case reports were also included if felt important. PMID:27380973

  17. Managing Linguistic Data Summaries in Advanced P2P Applications

    NASA Astrophysics Data System (ADS)

    Hayek, Rabab; Raschia, Guillaume; Valduriez, Patrick; Mouaddib, Noureddine

    As the amount of stored data increases, data localization techniques become no longer sufficient in P2P systems. A practical approach is to rely on compact database summaries rather than raw database records, whose access is costly in large P2P systems. In this chapter, we describe a solution for managing linguistic data summaries in advanced P2P applications which are dealing with semantically rich data. The produced summaries are synthetic, multidimensional views over relational tables. The novelty of this proposal relies on the double summary exploitation in distributed P2P systems. First, as semantic indexes, they support locating relevant nodes based on their data descriptions. Second, due to their intelligibility, these summaries can be directly queried and thus approximately answer a query without the need for exploring original data. The proposed solution consists first in defining a summary model for hierarchical P2P systems. Second, appropriate algorithms for summary creation and maintenance are presented. A query processing mechanism, which relies on summary querying, is then proposed to demonstrate the benefits that might be obtained from summary exploitation.

  18. Informative Top-k Retrieval for Advanced Skill Management

    NASA Astrophysics Data System (ADS)

    Colucci, Simona; di Noia, Tommaso; Ragone, Azzurra; Ruta, Michele; Straccia, Umberto; Tinelli, Eufemia

    The paper presents a knowledge-based framework for skills and talent management based on an advanced matchmaking between profiles of candidates and available job positions. Interestingly, informative content of top-k retrieval is enriched through semantic capabilities. The proposed approach allows to: (1) express a requested profile in terms of both hard constraints and soft ones; (2) provide a ranking function based also on qualitative attributes of a profile; (3) explain the resulting outcomes (given a job request, a motivation for the obtained score of each selected profile is provided). Top-k retrieval allows to select most promising candidates according to an ontology formalizing the domain knowledge. Such a knowledge is further exploited to provide a semantic-based explanation of missing or conflicting features in retrieved profiles. They also indicate additional profile characteristics emerging by the retrieval procedure for a further request refinement. A concrete case study followed by an exhaustive experimental campaign is reported to prove the approach effectiveness.

  19. Recent advances in multidisciplinary management of hepatocellular carcinoma

    PubMed Central

    Gomaa, Asmaa I; Waked, Imam

    2015-01-01

    The incidence of hepatocellular carcinoma (HCC) is increasing, and it is currently the second leading cause of cancer-related death worldwide. Potentially curative treatment options for HCC include resection, transplantation, and percutaneous ablation, whereas palliative treatments include trans-arterial chemoembolization (TACE), radioembolization, and systemic treatments. Due to the diversity of available treatment options and patients’ presentations, a multidisciplinary team should decide clinical management of HCC, according to tumor characteristics and stage of liver disease. Potentially curative treatments are suitable for very-early- and early-stage HCC. However, the vast majority of HCC patients are diagnosed in later stages, where the tumor characteristics or progress of liver disease prevent curative interventions. For patients with intermediate-stage HCC, TACE and radioembolization improve survival and are being evaluated in addition to potentially curative therapies or with systemic targeted therapy. There is currently no effective systemic chemotherapy, immunologic, or hormonal therapy for HCC, and sorafenib is the only approved molecular-targeted treatment for advanced HCC. Other targeted agents are under investigation; trials comparing new agents in combination with sorafenib are ongoing. Combinations of systemic targeted therapies with local treatments are being evaluated for further improvements in HCC patient outcomes. This article provides an updated and comprehensive overview of the current standards and trends in the treatment of HCC. PMID:25866604

  20. Advanced Health Management System for the Space Shuttle Main Engine

    NASA Technical Reports Server (NTRS)

    Davidson, Matt; Stephens, John; Rodela, Chris

    2006-01-01

    Pratt & Whitney Rocketdyne, Inc., in cooperation with NASA-Marshall Space Flight Center (MSFC), has developed a new Advanced Health Management System (AHMS) controller for the Space Shuttle Main Engine (SSME) that will increase the probability of successfully placing the shuttle into the intended orbit and increase the safety of the Space Transportation System (STS) launches. The AHMS is an upgrade o the current Block II engine controller whose primary component is an improved vibration monitoring system called the Real-Time Vibration Monitoring System (RTVMS) that can effectively and reliably monitor the state of the high pressure turbomachinery and provide engine protection through a new synchronous vibration redline which enables engine shutdown if the vibration exceeds predetermined thresholds. The introduction of this system required improvements and modification to the Block II controller such as redesigning the Digital Computer Unit (DCU) memory and the Flight Accelerometer Safety Cut-Off System (FASCOS) circuitry, eliminating the existing memory retention batteries, installation of the Digital Signal Processor (DSP) technology, and installation of a High Speed Serial Interface (HSSI) with accompanying outside world connectors. Test stand hot-fire testing along with lab testing have verified successful implementation and is expected to reduce the probability of catastrophic engine failures during the shuttle ascent phase and improve safely by about 23% according to the Quantitative Risk Assessment System (QRAS), leading to a safer and more reliable SSME.

  1. Impact of Forest Management on Future Forest Carbon Storage in Alaska Coastal Forests

    NASA Astrophysics Data System (ADS)

    Zhou, X.; Kushch, S. A.

    2014-12-01

    The forest in Coastal Alaska are unique in many ways. Two groups of forest types occur in the Alaska region: boreal and temperate rain forests. About eighty-eight percent of these forests are in public ownership. High proportations of reserved forests and old-growth forests make the forests in coastal Alaska differ from that in other coastal regions. This study is focused on how forest management actions may impact the future carbon stocks and flux in coastal Alaska forests. The Forest Inventory and Analysis (FIA) data collected by US Forest Service are the primary data used for estimation of current carbon storage and projections of future forest carbon storage for all forest carbon pools in Alaska coastal forests under different management scenarios and climate change effect.

  2. Numerical analysis of charge and discharge characteristics of advanced energy storage systems

    NASA Astrophysics Data System (ADS)

    Kanari, Katsuhiko

    1992-01-01

    A thermal energy storage system using phase-change materials and flow batteries was investigated, and computer simulation models were developed for estimating charge and discharge characteristics of latent thermal energy storage units using high-density polyethylene, pentaerithritol, and molten salts. These models are useful for evaluating the charge and discharge characteristics of the energy storage system, conducting feasibility studies for new applications, and for optimizing thermal-energy storage units. Computer simulation models were also developed for the analysis of shunt current flowing in redox flow and Zn/Br batteries. These models can be used for estimating the round-trip efficiencies, the state of charge, the terminal voltage, and, in case of Zn/Br battery, for the distribution of zinc metal deposited in the cells in a stack.

  3. Electrochemical investigations of advanced materials for microelectronic and energy storage devices

    NASA Astrophysics Data System (ADS)

    Goonetilleke, Pubudu Chaminda

    A broad range of electrochemical techniques are employed in this work to study a selected set of advanced materials for applications in microelectronics and energy storage devices. The primary motivation of this study has been to explore the capabilities of certain modern electrochemical techniques in a number of emerging areas of material processing and characterization. The work includes both aqueous and non-aqueous systems, with applications in two rather general areas of technology, namely microelectronics and energy storage. The sub-systems selected for investigation are: (i) Electrochemical mechanical and chemical mechanical planarization (ECMP and CMP, respectively), (ii) Carbon nanotubes in combination with room temperature ionic liquids (ILs), and (iii) Cathode materials for high-performance Li ion batteries. The first group of systems represents an important building block in the fabrication of microelectronic devices. The second and third groups of systems are relevant for new energy storage technologies, and have generated immense interests in recent years. A common feature of these different systems is that they all are associated with complex surface reactions that dictate the performance of the devices based on them. Fundamental understanding of these reactions is crucial to further development and expansion of their associated technologies. It is the complex mechanistic details of these surface reactions that we address using a judicious combination of a number of state of the art electrochemical techniques. The main electrochemical techniques used in this work include: (i) Cyclic voltammetry (CV) and slow scan cyclic voltammetry (SSCV, a special case of CV); (ii) Galvanostatic (or current-controlled) measurements; (iii) Electrochemical impedance spectroscopy (EIS), based on two different methodologies, namely, Fourier transform EIS (FT-EIS, capable of studying fast reaction kinetics in a time-resolved mode), and EIS using frequency response

  4. Concepts for design of an energy management system incorporating dispersed storage and generation

    NASA Technical Reports Server (NTRS)

    Kirkham, H.; Koerner, T.; Nightingale, D.

    1981-01-01

    New forms of generation based on renewable resources must be managed as part of existing power systems in order to be utilized with maximum effectiveness. Many of these generators are by their very nature dispersed or small, so that they will be connected to the distribution part of the power system. This situation poses new questions of control and protection, and the intermittent nature of some of the energy sources poses problems of scheduling and dispatch. Under the assumption that the general objectives of energy management will remain unchanged, the impact of dispersed storage and generation on some of the specific functions of power system control and its hardware are discussed.

  5. An information management system for a spent nuclear fuel interim storage facility.

    SciTech Connect

    Finch, Robert J.; Chiu, Hsien-Lang; Giles, Todd; Horak, Karl Emanuel; Jow, Hong-Nian

    2010-12-01

    We describe an integrated information management system for an independent spent fuel dry-storage installation (ISFSI) that can provide for (1) secure and authenticated data collection, (2) data analysis, (3) dissemination of information to appropriate stakeholders via a secure network, and (4) increased public confidence and support of the facility licensing and operation through increased transparency. This information management system is part of a collaborative project between Sandia National Laboratories, Taiwan Power Co., and the Fuel Cycle Materials Administration of Taiwan's Atomic Energy Council, which is investigating how to implement this concept.

  6. Australia's TERN: Advancing Ecosystem Data Management in Australia

    NASA Astrophysics Data System (ADS)

    Phinn, S. R.; Christensen, R.; Guru, S.

    2013-12-01

    licensing framework suitable for ecosystem data, national standards for metadata, a DOI-minting service, and context-appropriate data repositories and portals. The TERN Data infrastructure is based on loosely coupled 'network of networks.' Overall, the data formats used across the TERN facilities vary from NetCDF, comma-separated values and descriptive documents. Metadata standards include ISO19115, Ecological Metadata Language and rich semantic enabled contextual information. Data services vary from Web Mapping Service, Web Feature Service, OpeNDAP, file servers and KNB Metacat. These approaches enable each data collection facility to maintain their discipline based data collection and storage protocols. TERN facility meta-data are harvested regularly for the central TERN Data Discovery Portal and converted to a national standard format. This approach enables centralised discovery, access, and re-use of data simply and effectively, while maintaining disciplinary diversity. Effort is still required to support the cultural shift towards acceptance of effective data management, publication, sharing and re-use as standard practice. To this end TERN's future activities will be directed to supporting this transformation and undertaking ';education' to enable ecosystem scientists to take full advantage of TERN's infrastructure, and providing training and guidance for best practice data management.

  7. Radioactive waste shipments to Hanford retrievable storage from Westinghouse Advanced Reactors and Nuclear Fuels Divisions, Cheswick, Pennsylvania

    SciTech Connect

    Duncan, D.; Pottmeyer, J.A.; Weyns, M.I.; Dicenso, K.D.; DeLorenzo, D.S.

    1994-04-01

    During the next two decades the transuranic (TRU) waste now stored in the burial trenches and storage facilities at the Hanford Sits in southeastern Washington State is to be retrieved, processed at the Waste Receiving and Processing Facility, and shipped to the Waste Isolation Pilot Plant (WIPP), near Carlsbad, New Mexico for final disposal. Approximately 5.7 percent of the TRU waste to be retrieved for shipment to WIPP was generated by the decontamination and decommissioning (D&D) of the Westinghouse Advanced Reactors Division (WARD) and the Westinghouse Nuclear Fuels Division (WNFD) in Cheswick, Pennsylvania and shipped to the Hanford Sits for storage. This report characterizes these radioactive solid wastes using process knowledge, existing records, and oral history interviews.

  8. Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations: Data used in Geosphere Journal Article

    DOE Data Explorer

    Thomas A. Buscheck

    2015-06-01

    This data submission is for Phase 2 of Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations, which focuses on multi-fluid (CO2 and brine) geothermal energy production and diurnal bulk energy storage in geologic settings that are suitable for geologic CO2 storage. This data submission includes all data used in the Geosphere Journal article by Buscheck et al (2016). All assumptions are discussed in that article.

  9. Design and Implementation of an Educational Program in Advanced Airway Management for Anesthesiology Residents

    PubMed Central

    Borovcanin, Zana; Shapiro, Janine R.

    2012-01-01

    Education and training in advanced airway management as part of an anesthesiology residency program is necessary to help residents attain the status of expert in difficult airway management. The Accreditation Council for Graduate Medical Education (ACGME) emphasizes that residents in anesthesiology must obtain significant experience with a broad spectrum of airway management techniques. However, there is no specific number required as a minimum clinical experience that should be obtained in order to ensure competency. We have developed a curriculum for a new Advanced Airway Techniques rotation. This rotation is supplemented with a hands-on Difficult Airway Workshop. We describe here this comprehensive advanced airway management educational program at our institution. Future studies will focus on determining if education in advanced airway management results in a decrease in airway related morbidity and mortality and overall better patients' outcome during difficult airway management. PMID:22505885

  10. An emerging network storage management standard: Media error monitoring and reporting information (MEMRI) - to determine optical tape data integrity

    NASA Technical Reports Server (NTRS)

    Podio, Fernando; Vollrath, William; Williams, Joel; Kobler, Ben; Crouse, Don

    1998-01-01

    Sophisticated network storage management applications are rapidly evolving to satisfy a market demand for highly reliable data storage systems with large data storage capacities and performance requirements. To preserve a high degree of data integrity, these applications must rely on intelligent data storage devices that can provide reliable indicators of data degradation. Error correction activity generally occurs within storage devices without notification to the host. Early indicators of degradation and media error monitoring 333 and reporting (MEMR) techniques implemented in data storage devices allow network storage management applications to notify system administrators of these events and to take appropriate corrective actions before catastrophic errors occur. Although MEMR techniques have been implemented in data storage devices for many years, until 1996 no MEMR standards existed. In 1996 the American National Standards Institute (ANSI) approved the only known (world-wide) industry standard specifying MEMR techniques to verify stored data on optical disks. This industry standard was developed under the auspices of the Association for Information and Image Management (AIIM). A recently formed AIIM Optical Tape Subcommittee initiated the development of another data integrity standard specifying a set of media error monitoring tools and media error monitoring information (MEMRI) to verify stored data on optical tape media. This paper discusses the need for intelligent storage devices that can provide data integrity metadata, the content of the existing data integrity standard for optical disks, and the content of the MEMRI standard being developed by the AIIM Optical Tape Subcommittee.

  11. Advanced Coupled Simulation of Borehole Thermal Energy Storage Systems and Above Ground Installations

    NASA Astrophysics Data System (ADS)

    Welsch, Bastian; Rühaak, Wolfram; Schulte, Daniel O.; Bär, Kristian; Sass, Ingo

    2016-04-01

    Seasonal thermal energy storage in borehole heat exchanger arrays is a promising technology to reduce primary energy consumption and carbon dioxide emissions. These systems usually consist of several subsystems like the heat source (e.g. solarthermics or a combined heat and power plant), the heat consumer (e.g. a heating system), diurnal storages (i.e. water tanks), the borehole thermal energy storage, additional heat sources for peak load coverage (e.g. a heat pump or a gas boiler) and the distribution network. For the design of an integrated system, numerical simulations of all subsystems are imperative. A separate simulation of the borehole energy storage is well-established but represents a simplification. In reality, the subsystems interact with each other. The fluid temperatures of the heat generation system, the heating system and the underground storage are interdependent and affect the performance of each subsystem. To take into account these interdependencies, we coupled a software for the simulation of the above ground facilities with a finite element software for the modeling of the heat flow in the subsurface and the borehole heat exchangers. This allows for a more realistic view on the entire system. Consequently, a finer adjustment of the system components and a more precise prognosis of the system's performance can be ensured.

  12. Assessment of economically optimal water management and geospatial potential for large-scale water storage

    NASA Astrophysics Data System (ADS)

    Weerasinghe, Harshi; Schneider, Uwe A.

    2010-05-01

    Assessment of economically optimal water management and geospatial potential for large-scale water storage Weerasinghe, Harshi; Schneider, Uwe A Water is an essential but limited and vulnerable resource for all socio-economic development and for maintaining healthy ecosystems. Water scarcity accelerated due to population expansion, improved living standards, and rapid growth in economic activities, has profound environmental and social implications. These include severe environmental degradation, declining groundwater levels, and increasing problems of water conflicts. Water scarcity is predicted to be one of the key factors limiting development in the 21st century. Climate scientists have projected spatial and temporal changes in precipitation and changes in the probability of intense floods and droughts in the future. As scarcity of accessible and usable water increases, demand for efficient water management and adaptation strategies increases as well. Addressing water scarcity requires an intersectoral and multidisciplinary approach in managing water resources. This would in return safeguard the social welfare and the economical benefit to be at their optimal balance without compromising the sustainability of ecosystems. This paper presents a geographically explicit method to assess the potential for water storage with reservoirs and a dynamic model that identifies the dimensions and material requirements under an economically optimal water management plan. The methodology is applied to the Elbe and Nile river basins. Input data for geospatial analysis at watershed level are taken from global data repositories and include data on elevation, rainfall, soil texture, soil depth, drainage, land use and land cover; which are then downscaled to 1km spatial resolution. Runoff potential for different combinations of land use and hydraulic soil groups and for mean annual precipitation levels are derived by the SCS-CN method. Using the overlay and decision tree algorithms

  13. Expert systems applied to fault isolation and energy storage management, phase 2

    NASA Technical Reports Server (NTRS)

    1987-01-01

    A user's guide for the Fault Isolation and Energy Storage (FIES) II system is provided. Included are a brief discussion of the background and scope of this project, a discussion of basic and advanced operating installation and problem determination procedures for the FIES II system and information on hardware and software design and implementation. A number of appendices are provided including a detailed specification for the microprocessor software, a detailed description of the expert system rule base and a description and listings of the LISP interface software.

  14. Advances in the management of HIV/HCV coinfection.

    PubMed

    Mandorfer, Mattias; Schwabl, Philipp; Steiner, Sebastian; Reiberger, Thomas; Peck-Radosavljevic, Markus

    2016-05-01

    HCV coinfection has emerged as a major cause of non-AIDS-related morbidity and mortality in HIV-positive patients. As a consequence of the availability of modern combined antiretroviral therapy regimens, for optimally managed HIV/HCV-coinfected patients, the rates of liver fibrosis progression and the risk of liver-related events are increasingly similar to those of HCV-monoinfected patients. Moreover, our understanding of modulators of liver disease progression has greatly improved. In addition to immune status, endocrine, metabolic, genetic and viral factors are closely interrelated and might be important determinants of liver disease progression. In the last decade, a variety of serologic and radiographic tests for noninvasive liver disease staging have been extensively validated and are commonly used in HIV/HCV-coinfected patients. Sustained virologic response prevents end-stage liver disease, hepatocellular carcinoma, and death, with an even greater effect size in HIV-positive compared to HIV-negative patients. As interferon-free regimens achieve comparable rates of sustained virologic response in HIV-negative and HIV-positive patients, HIV/HCV-coinfected patients should from now on be referred to as a special, rather than a difficult-to-treat, population. Our comprehensive review covers all relevant aspects of HIV/HCV coinfection. Beginning with the changing epidemiology, it also provides new insights into the natural history of this condition and gives an overview on non-invasive techniques for the staging of liver disease. Furthermore, it outlines current recommendations for the treatment of acute hepatitis C and summarizes the unprecedented advances in the field of chronic hepatitis C therapy. PMID:26758592

  15. Advanced latent heat of fusion thermal energy storage for solar power systems

    NASA Technical Reports Server (NTRS)

    Phillips, W. M.; Stearns, J. W.

    1985-01-01

    The use of solar thermal power systems coupled with thermal energy storage (TES) is being studied for both terrestrial and space applications. In the case of terrestrial applications, it was found that one or two hours of TES could shift the insolation peak (solar noon) to coincide with user peak loads. The use of a phase change material (PCM) is attractive because of the higher energy storage density which can be achieved. However, the use of PCM has also certain disadvantages which must be addressed. Proof of concept testing was undertaken to evaluate corrosive effects and thermal ratcheting effects in a slurry system. It is concluded that the considered alkali metal/alkali salt slurry approach to TES appears to be very viable, taking into account an elimination of thermal ratcheting in storage systems and the reduction of corrosive effects. The approach appears to be useful for an employment involving temperatures applicable to Brayton or Stirling cycles.

  16. AN INTERREGIONAL COMPARISON OF CHANNEL STRUCTURE, TRANSIENT STORAGE AND NUTRIENT UPTAKE IN STREAMS DRAINING MANAGED AND OLD GROWTH WATERSHEDS

    EPA Science Inventory

    We compared stream channel structure (width, depth, substrate composition) and riparian canopy with transient storage and nutrient uptake in 32 streams draining old-growth and managed watersheds in the Appalachian Mountains (North Carolina), Ouachita Mountains (Arkansas), Cascade...

  17. Research Studies on Advanced Optical Module/Head Designs for Optical Data Storage

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Preprints are presented from the recent 1992 Optical Data Storage meeting in San Jose. The papers are divided into the following topical areas: Magneto-optical media (Modeling/design and fabrication/characterization/testing); Optical heads (holographic optical elements); and Optical heads (integrated optics). Some representative titles are as follow: Diffraction analysis and evaluation of several focus and track error detection schemes for magneto-optical disk systems; Proposal for massively parallel data storage system; Transfer function characteristics of super resolving systems; Modeling and measurement of a micro-optic beam deflector; Oxidation processes in magneto-optic and related materials; and A modal analysis of lamellar diffraction gratings in conical mountings.

  18. [Recent advances in the diagnosis and treatment of lysosomal storage diseases].

    PubMed

    Wu, Xi-ru; Bao, Xin-hua

    2005-08-18

    Lysosomal storage diseases are a group of genetic disorders that result from the defect in lysosomal function. Signs and symptoms are variable, it is difficult to diagnose this group of disease merely by the clinical manifestation. The diagnosis usually is made by measuring the activity of the corresponding enzyme. Gene mutational analysis is useful for the diagnosis of some of the lysosome storage diseases. The treatment has focused on the replacement of the defective enzyme responsible for the disease and the hematopoietic stem cell transplantation. Both of them have achieved exciting outcomes in some of the diseases. PMID:16086072

  19. Performance testing of 10 kW-class advanced batteries for electric energy storage systems in Japan

    NASA Astrophysics Data System (ADS)

    Futamata, M.; Higuchi, S.; Nakamura, O.; Ogino, I.; Takada, Y.; Okazaki, S.; Ashimura, S.; Takahashi, S.

    1988-09-01

    The results of the performance testing of 10 kW-class advanced batteries — Na-S, Zn-Cl 2, Zn-Br 2 and redox-flow type batteries — are summarized. Energy efficiency and capacity at three discharge rates are presented in addition to energy density, self-discharge rate, estimated short circuit current, etc. It was evident that the performance of the advanced batteries was adequate to achieve the project goals for electrical energy storage. Further improvements are needed in the areas of self-discharge, electric insulation, and auxiliary systems. Based on continued technical progress, there is reasonable expectation that pilot plants of 1 MW (8 MW h) will be constructed and demonstrated in the next phase of the project.

  20. Use of transportable storage casks in the nuclear waste management system: Appendices

    SciTech Connect

    Not Available

    1987-12-01

    A study was performed to determine the viability of the use of transportable storage casks (TSCs), and other metal casks that are designed primarily for storage but which might be used to ship their stored contents to DOE on a one-time use basis (referred to in this study as storage only casks, or SOCs), in the combined utility/DOE spent fuel management system. The viability of the use of TSCs and SOCs was assessed in terms of the costs and savings involved in their use, the sensitivity of these costs and savings to changes in the capacity and cost of fabrication of the casks, the impacts of variation in cask design features on cost and radiation exposure of personnel, and their prospective use in connection with the transport of defense high level wastes. Estimates were developed of the costs of acquiring and handling of TSCs and SOCs at reactor sites. For comparison purposes, similar costs were developed for the use of concrete storage casks at reactor sites. Estimates of the savings involved to the DOE system as a result of receiving spent fuel in TSCs or SOCs were separately developed. These costs are developed and presented in Volume 2, Appendices A through J.

  1. CPP-603 Underwater Fuel Storage Facility Site Integrated Stabilization Management Plan (SISMP), Volume I

    SciTech Connect

    Denney, R.D.

    1995-10-01

    The CPP-603 Underwater Fuel Storage Facility (UFSF) Site Integrated Stabilization Management Plan (SISMP) has been constructed to describe the activities required for the relocation of spent nuclear fuel (SNF) from the CPP-603 facility. These activities are the only Idaho National Engineering Laboratory (INEL) actions identified in the Implementation Plan developed to meet the requirements of the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1 to the Secretary of Energy regarding an improved schedule for remediation in the Defense Nuclear Facilities Complex. As described in the DNFSB Recommendation 94-1 Implementation Plan, issued February 28, 1995, an INEL Spent Nuclear Fuel Management Plan is currently under development to direct the placement of SNF currently in existing INEL facilities into interim storage, and to address the coordination of intrasite SNF movements with new receipts and intersite transfers that were identified in the DOE SNF Programmatic and INEL Environmental Restoration and Waste Management Environmental Impact Statement Record, of Decision. This SISMP will be a subset of the INEL Spent Nuclear Fuel Management Plan and the activities described are being coordinated with other INEL SNF management activities. The CPP-603 relocation activities have been assigned a high priority so that established milestones will be meet, but there will be some cases where other activities will take precedence in utilization of available resources. The Draft INEL Site Integrated Stabilization Management Plan (SISMP), INEL-94/0279, Draft Rev. 2, dated March 10, 1995, is being superseded by the INEL Spent Nuclear Fuel Management Plan and this CPP-603 specific SISMP.

  2. Advancement of Systems Designs and Key Engineering Technologies for Materials Based Hydrogen Storage

    SciTech Connect

    van Hassel, Bart A.

    2015-09-18

    UTRC lead the development of the Simulink Framework model that enables a comparison of different hydrogen storage systems on a common basis. The Simulink Framework model was disseminated on the www.HSECoE.org website that is hosted by NREL. UTRC contributed to a better understanding of the safety aspects of the proposed hydrogen storage systems. UTRC also participated in the Failure Mode and Effect Analysis of both the chemical- and the adsorbent-based hydrogen storage system during Phase 2 of the Hydrogen Storage Engineering Center of Excellence. UTRC designed a hydrogen storage system with a reversible metal hydride material in a compacted form for light-duty vehicles with a 5.6 kg H2 storage capacity, giving it a 300 miles range. It contains a heat exchanger that enables efficient cooling of the metal hydride material during hydrogen absorption in order to meet the 3.3 minute refueling time target. It has been shown through computation that the kinetics of hydrogen absorption of Ti-catalyzed NaAlH4 was ultimately limiting the rate of hydrogen absorption to 85% of the material capacity in 3.3 minutes. An inverse analysis was performed in order to determine the material property requirements in order for a metal hydride based hydrogen storage system to meet the DOE targets. Work on metal hydride storage systems was halted after the Phase 1 to Phase 2 review due to the lack of metal hydride materials with the required material properties. UTRC contributed to the design of a chemical hydrogen storage system by developing an adsorbent for removing the impurity ammonia from the hydrogen gas, by developing a system to meter the transport of Ammonia Borane (AB) powder to a thermolysis reactor, and by developing a gas-liquid-separator (GLS) for the separation of hydrogen gas from AB slurry in silicone oil. Stripping impurities from hydrogen gas is essential for a long life of the fuel cell system on board of a vehicle. Work on solid transport of AB was halted after the

  3. Advanced Simulation Capability for Environmental Management (ASCEM) Phase II Demonstration

    SciTech Connect

    Freshley, M.; Hubbard, S.; Flach, G.; Freedman, V.; Agarwal, D.; Andre, B.; Bott, Y.; Chen, X.; Davis, J.; Faybishenko, B.; Gorton, I.; Murray, C.; Moulton, D.; Meyer, J.; Rockhold, M.; Shoshani, A.; Steefel, C.; Wainwright, H.; Waichler, S.

    2012-09-28

    In 2009, the National Academies of Science (NAS) reviewed and validated the U.S. Department of Energy Office of Environmental Management (EM) Technology Program in its publication, Advice on the Department of Energy’s Cleanup Technology Roadmap: Gaps and Bridges. The NAS report outlined prioritization needs for the Groundwater and Soil Remediation Roadmap, concluded that contaminant behavior in the subsurface is poorly understood, and recommended further research in this area as a high priority. To address this NAS concern, the EM Office of Site Restoration began supporting the development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is a state-of-the-art scientific approach that uses an integration of toolsets for understanding and predicting contaminant fate and transport in natural and engineered systems. The ASCEM modeling toolset is modular and open source. It is divided into three thrust areas: Multi-Process High Performance Computing (HPC), Platform and Integrated Toolsets, and Site Applications. The ASCEM toolsets will facilitate integrated approaches to modeling and site characterization that enable robust and standardized assessments of performance and risk for EM cleanup and closure activities. During fiscal year 2012, the ASCEM project continued to make significant progress in capabilities development. Capability development occurred in both the Platform and Integrated Toolsets and Multi-Process HPC Simulator areas. The new Platform and Integrated Toolsets capabilities provide the user an interface and the tools necessary for end-to-end model development that includes conceptual model definition, data management for model input, model calibration and uncertainty analysis, and model output processing including visualization. The new HPC Simulator capabilities target increased functionality of process model representations, toolsets for interaction with the Platform, and model confidence testing and verification for

  4. An analog RF gap voltage regulation system for the Advanced Photon Source storage ring.

    SciTech Connect

    Horan, D.

    1999-04-13

    An analog rf gap voltage regulation system has been designed and built at Argonne National Laboratory to maintain constant total storage ring rf gap voltage, independent of beam loading and cavity tuning effects. The design uses feedback control of the klystron mod-anode voltage to vary the amount of rf power fed to the storage ring cavities. The system consists of two independent feedback loops, each regulating the combined rf gap voltages of eight storage ring cavities by varying the output power of either one or two rf stations, depending on the mode of operation. It provides full operator control and permissive logic to permit feedback control of the rf system output power only if proper conditions are met. The feedback system uses envelope-detected cavity field probe outputs as the feedback signal. Two different methods of combining the individual field probe signals were used to generate a relative DC level representing one-half of the total storage ring rf voltage, an envelope-detected vector sum of the field probe rf signals, and the DC sum of individual field probe envelope detector outputs. The merits of both methods are discussed. The klystron high-voltage power supply (HVPS) units are fitted with an analog interface for external control of the mod-anode voltage level, using a four-quadrant analog multiplier to modulate the HVPS mod-anode voltage regulator set-point in response to feedback system commands.

  5. V1.6 Development of Advanced Manufacturing Technologies for Low Cost Hydrogen Storage Vessels

    SciTech Connect

    Leavitt, Mark; Lam, Patrick; Nelson, Karl M.; johnson, Brice A.; Johnson, Kenneth I.; Alvine, Kyle J.; Ruiz, Antonio; Adams, Jesse

    2012-10-01

    The goal of this project is to develop an innovative manufacturing process for Type IV high-pressure hydrogen storage vessels, with the intent to significantly lower manufacturing costs. Part of the development is to integrate the features of high precision AFP and commercial FW. Evaluation of an alternative fiber to replace a portion of the baseline fiber will help to reduce costs further.

  6. Remote tong/tool latch and storage bracket for an advanced servo-manipulator

    DOEpatents

    Nicholson, John R.

    1990-01-01

    An arrangement for stowing releasable end effectors for manipulator arms wherein the end effector includes a releasable latch mechanism for connecting the end effector to the manipulator arm, and a storage holder is provided which includes an arrangement for actuating the latch mechanism as the end effector is moved into and out of the holder by the action of the manipulator arm.

  7. Nuclear Storage Facility Inventory and Information Management using the GraFIC Software.

    SciTech Connect

    Hickerson, T.W.

    1999-05-04

    Oak Ridge has developed an intelligent facility and information management system to provide near real time, verifiable status of safeguarded materials in a nuclear storage facility. The Graphical Facility Information System (GraFIC{trademark}) is a versatile software package designed to operate in a distributed computing environment. GraFIC{trademark} is integrated with a suite of rugged, low-cost sensors that remotely monitor the physical and/or assigned attributes associated with stored nuclear materials and reports item and facility activity to an unlimited number of authorized clients. The software also contains facility management tools to assist with space planning, record management, item location, and a variety of other facilities needs.

  8. ADVANCED BIOTELEMETRY FOR RESOURCE MANAGEMENT ON MILITARY LANDS (CS-759)

    EPA Science Inventory

    The process of natural resource management and planning begins with a thorough inventory and description of a natural system's flora and fauna. This information is critical for the development and implementation of effective integrated natural resource management plans. Such plan...

  9. MRS (monitored retrievable storage) systems study Task G report: The role and functions of surface storage of radioactive material in the federal waste management system

    SciTech Connect

    Wood, T.W.; Short, S.M.; Woodruff, M.G.; Altenhofen, M.K.; MacKay, C.A.

    1989-04-01

    This is one of nine studies undertaken by contractors to the US Department of Energy (DOE), Office of Civilian Radioactive Waste Management (OCRWM), to provide a technical basis for re-evaluating the role of a monitored retrievable storage (MRS) facility. The study investigates the functions that could be performed by surface storage of radioactive material within the federal radioactive waste management system, including enabling acceptance of spent fuel from utility owners, scheduling of waste-preparation processes within the system, enhancement of system operating reliability, and conditioning the thermal (decay heat) characteristics of spent fuel emplaced in a repository. The analysis focuses particularly on the effects of storage capacity and DOE acceptance schedule on power reactors. Figures of merit developed include the storage capacity (in metric tons of uranium (MTU)) required to be added beyond currently estimated maximum spent fuel storage capacities and its associated cost, and the number of years that spent fuel pools would remain open after last discharge (in pool-years) and the cost of this period of operation. 27 refs., 36 figs., 18 tabs.

  10. Carbon nitride in energy conversion and storage: recent advances and future prospects.

    PubMed

    Gong, Yutong; Li, Mingming; Wang, Yong

    2015-03-01

    With the explosive growth of energy consumption, the exploration of highly efficient energy conversion and storage devices becomes increasingly important. Fuel cells, supercapacitors, and lithium-ion batteries are among the most promising options. The innovation of these devices mainly resides in the development of high-performance electrode materials and catalysts. Graphitic carbon nitride (g-C3 N4 ), due to structural and chemical properties such as semiconductor optical properties, rich nitrogen content, and tunable porous structure, has drawn considerable attention and shown great potential as an electrode material or catalyst in energy conversion and storage devices. This review covers recent progress in g-C3 N4 -containing systems for fuel cells, electrocatalytic water splitting devices, supercapacitors, and lithium-ion batteries. The corresponding catalytic mechanisms and future research directions in these areas are also discussed. PMID:25688746

  11. Advanced Flywheel Composite Rotors: Low-Cost, High-Energy Density Flywheel Storage Grid Demonstration

    SciTech Connect

    2010-10-01

    GRIDS Project: Boeing is developing a new material for use in the rotor of a low-cost, high-energy flywheel storage technology. Flywheels store energy by increasing the speed of an internal rotor —slowing the rotor releases the energy back to the grid when needed. The faster the rotor spins, the more energy it can store. Boeing’s new material could drastically improve the energy stored in the rotor. The team will work to improve the storage capacity of their flywheels and increase the duration over which they store energy. The ultimate goal of this project is to create a flywheel system that can be scaled up for use by electric utility companies and produce power for a full hour at a cost of $100 per kilowatt hour.

  12. A Prototype Cryogenic Oxygen Storage and Delivery Subsystem for Advanced Spacesuits

    NASA Technical Reports Server (NTRS)

    Overbeeke, Arend; Hodgson, Edward; Paul, Heather; Geier, Harold; Bradt, Howard

    2007-01-01

    Future spacesuit systems for the exploration of Mars will need to be much lighter than current designs while at the same time reducing the consumption of water for crew cooling. One of the technology paths NASA has identified to achieve these objectives is the replacement of current high pressure oxygen storage technology in EVA systems with cryogenic technology that can simultaneously reduce the mass of tankage required for oxygen storage and enable the use of the stored oxygen as a means of cooling the EVA astronaut. During the past year NASA has funded Hamilton Sundstrand production of a prototype system demonstrating this capability in a design that will allow the cryogenic oxygen to be used in any attitude and gravity environment. This paper will describe the design and manufacture of the prototype system and present the results of preliminary testing to verify its performance characteristics. The potential significance and application of the system will also be discussed.

  13. A split-path schema-based RFID data storage model in supply chain management.

    PubMed

    Fan, Hua; Wu, Quanyuan; Lin, Yisong; Zhang, Jianfeng

    2013-01-01

    In modern supply chain management systems, Radio Frequency IDentification (RFID) technology has become an indispensable sensor technology and massive RFID data sets are expected to become commonplace. More and more space and time are needed to store and process such huge amounts of RFID data, and there is an increasing realization that the existing approaches cannot satisfy the requirements of RFID data management. In this paper, we present a split-path schema-based RFID data storage model. With a data separation mechanism, the massive RFID data produced in supply chain management systems can be stored and processed more efficiently. Then a tree structure-based path splitting approach is proposed to intelligently and automatically split the movement paths of products . Furthermore, based on the proposed new storage model, we design the relational schema to store the path information and time information of tags, and some typical query templates and SQL statements are defined. Finally, we conduct various experiments to measure the effect and performance of our model and demonstrate that it performs significantly better than the baseline approach in both the data expression and path-oriented RFID data query performance. PMID:23645112

  14. Influence of the energy management on the sizing of Electrical Energy Storage Systems in an aircraft

    NASA Astrophysics Data System (ADS)

    Devillers, Nathalie; Péra, Marie-Cécile; Bienaimé, Daniel; Grojo, Marie-Laure

    2014-12-01

    In an aircraft, Electrical Energy Storage Systems (EESS) are used as support to other sources in few mission phases in order to ensure the energy availability. They are also used as electrical smoothing devices in order to guarantee the required levels of reliability, stability and quality for an embedded electrical network. This paper deals with the association of two EESS: supercapacitors and secondary battery, which exhibit complementary properties. In this paper, a sizing method for both EESS is developed by taking into account their hybridization and their characteristics (such as capacity or depth-of-discharge) so as to minimize the global storage system weight. Moreover, an energy management based on a frequency approach is implemented to dispatch the power between all the sources. The influence of this management on the sizing is studied. Indeed the cut-off frequency of the low-pass filter is used as a setting parameter of the sizing algorithm. Finally, the sizing validity is assessed and discussed according to temperature constraints. Although battery performances are reduced at low temperature, the sizing determined with the algorithm at 20 °C is still valid on all the temperature range thanks to an adaptation of the energy management parameter.

  15. A Split-Path Schema-Based RFID Data Storage Model in Supply Chain Management

    PubMed Central

    Fan, Hua; Wu, Quanyuan; Lin, Yisong; Zhang, Jianfeng

    2013-01-01

    In modern supply chain management systems, Radio Frequency IDentification (RFID) technology has become an indispensable sensor technology and massive RFID data sets are expected to become commonplace. More and more space and time are needed to store and process such huge amounts of RFID data, and there is an increasing realization that the existing approaches cannot satisfy the requirements of RFID data management. In this paper, we present a split-path schema-based RFID data storage model. With a data separation mechanism, the massive RFID data produced in supply chain management systems can be stored and processed more efficiently. Then a tree structure-based path splitting approach is proposed to intelligently and automatically split the movement paths of products. Furthermore, based on the proposed new storage model, we design the relational schema to store the path information and time information of tags, and some typical query templates and SQL statements are defined. Finally, we conduct various experiments to measure the effect and performance of our model and demonstrate that it performs significantly better than the baseline approach in both the data expression and path-oriented RFID data query performance. PMID:23645112

  16. Advanced Energy Storage Life and Health Prognostics (INL) FY 2012 Annual Progress Report

    SciTech Connect

    Jon P. Christophersen

    2012-10-01

    The objective of this work is to develop methodologies that will accurately estimate state-of-health (SOH) and remaining useful life (RUL) of electrochemical energy storage devices using both offline and online (i.e., in-situ) techniques through: · A statistically robust offline battery calendar life estimator tool based on both testing and simulation, and · Novel onboard sensor technology for improved online battery diagnostics and prognostics.

  17. Managing the Perception of Advanced Technology Risks in Mission Proposals

    NASA Technical Reports Server (NTRS)

    Bellisario, Sebastian Nickolai

    2012-01-01

    Through my work in the project proposal office I became interested in how technology advancement efforts affect competitive mission proposals. Technology development allows for new instruments and functionality. However, including technology advancement in a mission proposal often increases perceived risk. Risk mitigation has a major impact on the overall evaluation of the proposal and whether the mission is selected. In order to evaluate the different approaches proposals took I compared the proposals claims of heritage and technology advancement to the sponsor feedback provided in the NASA debriefs. I examined a set of Discovery 2010 Mission proposals to draw patterns in how they were evaluated and come up with a set of recommendations for future mission proposals in how they should approach technology advancement to reduce the perceived risk.

  18. Wireless Sensor Network for Advanced Energy Management Solutions

    SciTech Connect

    Peter J. Theisen; Bin Lu, Charles J. Luebke

    2009-09-23

    Eaton has developed an advanced energy management solution that has been deployed to several Industries of the Future (IoF) sites. This demonstrated energy savings and reduced unscheduled downtime through an improved means for performing predictive diagnostics and energy efficiency estimation. Eaton has developed a suite of online, continuous, and inferential algorithms that utilize motor current signature analysis (MCSA) and motor power signature analysis (MPSA) techniques to detect and predict the health condition and energy usage condition of motors and their connect loads. Eaton has also developed a hardware and software platform that provided a means to develop and test these advanced algorithms in the field. Results from lab validation and field trials have demonstrated that the developed advanced algorithms are able to detect motor and load inefficiency and performance degradation. Eaton investigated the performance of Wireless Sensor Networks (WSN) within various industrial facilities to understand concerns about topology and environmental conditions that have precluded broad adoption by the industry to date. A Wireless Link Assessment System (WLAS), was used to validate wireless performance under a variety of conditions. Results demonstrated that wireless networks can provide adequate performance in most facilities when properly specified and deployed. Customers from various IoF expressed interest in applying wireless more broadly for selected applications, but continue to prefer utilizing existing, wired field bus networks for most sensor based applications that will tie into their existing Computerized Motor Maintenance Systems (CMMS). As a result, wireless technology was de-emphasized within the project, and a greater focus placed on energy efficiency/predictive diagnostics. Commercially available wireless networks were only utilized in field test sites to facilitate collection of motor wellness information, and no wireless sensor network products were

  19. Advanced monitoring technologies for the evaluation of demand-side management programs

    SciTech Connect

    De Almeida, A.T.; Vine, E.L.

    1993-06-01

    This report was commissioned by the California Institute for Energy Efficiency as part of its research mission to advance the energy efficiency and productivity of all end-use sectors in California. The aim of this study is to provide an assessment of the state-of-the-art technologies that can be used for monitoring and evaluating demand-side management (DSM) programs. Additionally, the study points out research, development, and demonstration projects whose implementation can contribute to a more accurate and cost-effective evaluation of the performance of end-use technologies. During the past two decades, technology developments in the fields of microelectronics, computers and communications had a large impact on monitoring equipment. The improvements achieved led to the appearance of increasingly powerful, convenient to use, and flexible equipment, enabling a wider application of end-use metering at a lower cost. Equipment specifications are getting closer and closer to an ``ideal`` monitoring system: Good accuracy, high reliability, moderate cost, large number of monitored end uses, large data storage capacity, flexible communications, non-intrusiveness, powerful preprocessing of data. This report briefly examines the following techniques that can be used for end-use monitoring: field test equipment, general purpose data loggers, run-time data loggers, utility-oriented data loggers, energy management systems, two-way communication, power line carrier techniques, direct and distributed load control, and non-intrusive load monitoring. The report concludes with recommendations for developing new measurement technologies, as well as additional research and development activities to support these efforts.

  20. DREAM: Distributed Resources for the Earth System Grid Federation (ESGF) Advanced Management

    NASA Astrophysics Data System (ADS)

    Williams, D. N.

    2015-12-01

    The data associated with climate research is often generated, accessed, stored, and analyzed on a mix of unique platforms. The volume, variety, velocity, and veracity of this data creates unique challenges as climate research attempts to move beyond stand-alone platforms to a system that truly integrates dispersed resources. Today, sharing data across multiple facilities is often a challenge due to the large variance in supporting infrastructures. This results in data being accessed and downloaded many times, which requires significant amounts of resources, places a heavy analytic development burden on the end users, and mismanaged resources. Working across U.S. federal agencies, international agencies, and multiple worldwide data centers, and spanning seven international network organizations, the Earth System Grid Federation (ESGF) has begun to solve this problem. Its architecture employs a system of geographically distributed peer nodes that are independently administered yet united by common federation protocols and application programming interfaces. However, significant challenges remain, including workflow provenance, modular and flexible deployment, scalability of a diverse set of computational resources, and more. Expanding on the existing ESGF, the Distributed Resources for the Earth System Grid Federation Advanced Management (DREAM) will ensure that the access, storage, movement, and analysis of the large quantities of data that are processed and produced by diverse science projects can be dynamically distributed with proper resource management. This system will enable data from an infinite number of diverse sources to be organized and accessed from anywhere on any device (including mobile platforms). The approach offers a powerful roadmap for the creation and integration of a unified knowledge base of an entire ecosystem, including its many geophysical, geographical, social, political, agricultural, energy, transportation, and cyber aspects. The

  1. Archiving and Managing Remote Sensing Data using State of the Art Storage Technologies

    NASA Astrophysics Data System (ADS)

    Lakshmi, B.; Chandrasekhara Reddy, C.; Kishore, S. V. S. R. K.

    2014-11-01

    Integrated Multi-mission Ground Segment for Earth Observation Satellites (IMGEOS) was established with an objective to eliminate human interaction to the maximum extent. All emergency data products will be delivered within an hour of acquisition through FTP delivery. All other standard data products will be delivered through FTP within a day. The IMGEOS activity was envisaged to reengineer the entire chain of operations at the ground segment facilities of NRSC at Shadnagar and Balanagar campuses to adopt an integrated multi-mission approach. To achieve this, the Information Technology Infrastructure was consolidated by implementing virtualized tiered storage and network computing infrastructure in a newly built Data Centre at Shadnagar Campus. One important activity that influences all other activities in the integrated multi-mission approach is the design of appropriate storage and network architecture for realizing all the envisaged operations in a highly streamlined, reliable and secure environment. Storage was consolidated based on the major factors like accessibility, long term data protection, availability, manageability and scalability. The broad operational activities are reception of satellite data, quick look, generation of browse, production of standard and valueadded data products, production chain management, data quality evaluation, quality control and product dissemination. For each of these activities, there are numerous other detailed sub-activities and pre-requisite tasks that need to be implemented to support the above operations. The IMGEOS architecture has taken care of choosing the right technology for the given data sizes, their movement and long-term lossless retention policies. Operational costs of the solution are kept to the minimum possible. Scalability of the solution is also ensured. The main function of the storage is to receive and store the acquired satellite data, facilitate high speed availability of the data for further

  2. The Grid Enabled Mass Storage System (GEMSS): the Storage and Data management system used at the INFN Tier1 at CNAF.

    NASA Astrophysics Data System (ADS)

    Ricci, Pier Paolo; Bonacorsi, Daniele; Cavalli, Alessandro; Dell'Agnello, Luca; Gregori, Daniele; Prosperini, Andrea; Rinaldi, Lorenzo; Sapunenko, Vladimir; Vagnoni, Vincenzo

    2012-12-01

    The storage system currently used in production at the INFN Tier1 at CNAF is the result of several years of case studies, software development and tests. This solution, called the Grid Enabled Mass Storage System (GEMSS), is based on a custom integration between a fast and reliable parallel filesystem (the IBM General Parallel File System, GPFS), with a complete integrated tape backend based on the Tivoli Storage Manager (TSM), which provides Hierarchical Storage Management (HSM) capabilities, and the Grid Storage Resource Manager (StoRM), providing access to grid users through a standard SRM interface. Since the start of the Large Hadron Collider (LHC) operation, all LHC experiments have been using GEMSS at CNAF for both disk data access and long-term archival on tape media. Moreover, during last year, GEMSS has become the standard solution for all other experiments hosted at CNAF, allowing the definitive consolidation of the data storage layer. Our choice has proved to be very successful during the last two years of production with continuous enhancements, accurate monitoring and effective customizations according to the end-user requests. In this paper a description of the system is reported, addressing recent developments and giving an overview of the administration and monitoring tools. We also discuss the solutions adopted in order to grant the maximum availability of the service and the latest optimization features within the data access process. Finally, we summarize the main results obtained during these last years of activity from the perspective of some of the end-users, showing the reliability and the high performances that can be achieved using GEMSS.

  3. Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations

    DOE Data Explorer

    Buscheck, Thomas A.

    2012-01-01

    Active Management of Integrated Geothermal–CO2 Storage Reservoirs in Sedimentary Formations: An Approach to Improve Energy Recovery and Mitigate Risk: FY1 Final Report The purpose of phase 1 is to determine the feasibility of integrating geologic CO2 storage (GCS) with geothermal energy production. Phase 1 includes reservoir analyses to determine injector/producer well schemes that balance the generation of economically useful flow rates at the producers with the need to manage reservoir overpressure to reduce the risks associated with overpressure, such as induced seismicity and CO2 leakage to overlying aquifers. Based on a range of well schemes, techno-economic analyses of the levelized cost of electricity (LCOE) are conducted to determine the economic benefits of integrating GCS with geothermal energy production. In addition to considering CO2 injection, reservoir analyses are conducted for nitrogen (N2) injection to investigate the potential benefits of incorporating N2 injection with integrated geothermal-GCS, as well as the use of N2 injection as a potential pressure-support and working-fluid option. Phase 1 includes preliminary environmental risk assessments of integrated geothermal-GCS, with the focus on managing reservoir overpressure. Phase 1 also includes an economic survey of pipeline costs, which will be applied in Phase 2 to the analysis of CO2 conveyance costs for techno-economics analyses of integrated geothermal-GCS reservoir sites. Phase 1 also includes a geospatial GIS survey of potential integrated geothermal-GCS reservoir sites, which will be used in Phase 2 to conduct sweet-spot analyses that determine where promising geothermal resources are co-located in sedimentary settings conducive to safe CO2 storage, as well as being in adequate proximity to large stationary CO2 sources.

  4. A risk management approach to double-shell tank waste volume versus storage capacity

    SciTech Connect

    Coles, G.A.; Thurkow, T.J.; Fritz, R.L.; Nuhlestein, L.O.; Allen, M.R.; Stuart, R.J.

    1996-01-01

    A risk-based assessment of the overall waste volume versus double-shell tank storage capacity was conducted to develop fallback positions for projections where the waste volume was at a high risk of exceeding capacity. This study was initiated to provide that assessment. A working simulation model was the primary deliverable of this study. The model validates the approach and demonstrates that simulation analysis can provide a method of tracking uncertainties in available data, assessing probabilities, and serves as a tool to be used by management to determine the consequences of various off-normal occurrences.

  5. System Configuration Management Implementation Procedure for the Canister Storage Building (CSB)

    SciTech Connect

    GARRISON, R.C.

    2000-11-28

    This document provides configuration management for the Distributed Control System (DCS), the Gaseous Effluent Monitoring System (GEMS-100) System, the Heating Ventilation and Air Conditioning (HVAC) Programmable Logic Controller (PLC), the Canister Receiving Crane (CRC) CRN-001 PLC, and both North and South vestibule door interlock system PLCs at the Canister Storage Building (CSB). This procedure identifies and defines software configuration items in the CSB control and monitoring systems, and defines configuration control throughout the system life cycle. Components of this control include: configuration status accounting; physical protection and control; and verification of the completeness and correctness of these items.

  6. A new class of solid oxide metal-air redox batteries for advanced stationary energy storage

    NASA Astrophysics Data System (ADS)

    Zhao, Xuan

    Cost-effective and large-scale energy storage technologies are a key enabler of grid modernization. Among energy storage technologies currently being researched, developed and deployed, rechargeable batteries are unique and important that can offer a myriad of advantages over the conventional large scale siting- and geography- constrained pumped-hydro and compressed-air energy storage systems. However, current rechargeable batteries still need many breakthroughs in material optimization and system design to become commercially viable for stationary energy storage. This PhD research project investigates the energy storage characteristics of a new class of rechargeable solid oxide metal-air redox batteries (SOMARBs) that combines a regenerative solid oxide fuel cell (RSOFC) and hydrogen chemical-looping component. The RSOFC serves as the "electrical functioning unit", alternating between the fuel cell and electrolysis mode to realize discharge and charge cycles, respectively, while the hydrogen chemical-looping component functions as an energy storage unit (ESU), performing electrical-chemical energy conversion in situ via a H2/H2O-mediated metal/metal oxide redox reaction. One of the distinctive features of the new battery from conventional storage batteries is the ESU that is physically separated from the electrodes of RSOFC, allowing it to freely expand and contract without impacting the mechanical integrity of the entire battery structure. This feature also allows an easy switch in the chemistry of this battery. The materials selection for ESU is critical to energy capacity, round-trip efficiency and cost effectiveness of the new battery. Me-MeOx redox couples with favorable thermodynamics and kinetics are highly preferable. The preliminary theoretical analysis suggests that Fe-based redox couples can be a promising candidate for operating at both high and low temperatures. Therefore, the Fe-based redox-couple systems have been selected as the baseline for this

  7. Advancements in integrating DSM and distributed generation and storage into T&D planning: Proceedings from the Third Annual Workshop

    SciTech Connect

    Not Available

    1994-09-01

    This third in a series of annual EPRI workshops focused on integrating demand-side management and distributed generation an into transmission and distribution planning. The workshop included utility case studies on integrated planning, results from utility pilot projects, analytical developments, and cross-departmental planning and implementation. In addition, the workshop featured information on advancements in area-specific planning and costing methods along with EPRI products that support utility integrated planning efforts.

  8. Storage Insects on Yam Chips and Their Traditional Management in Northern Benin

    PubMed Central

    Loko, Y. L.; Dansi, A.; Tamo, M.; Bokonon-Ganta, A. H.; Assogba, P.; Dansi, M.; Vodouhè, R.; Akoegninou, A.; Sanni, A.

    2013-01-01

    Twenty-five villages of Northern Benin were surveyed to identify the constraints of yam chips production, assess the diversity of storage insects on yam chips, and document farmers' perception of their impacts on the stocks and their traditional management practices. Damages due to storage insects (63.9% of responses) and insufficiency of insect-resistant varieties (16.7% of responses) were the major constraints of yam chips production. Twelve insect pest species were identified among which Dinoderus porcellus Lesne (Coleoptera, Bostrichidae) was by far the most important and the most distributed (97.44% of the samples). Three predators (Teretrius nigrescens Lewis, Xylocoris flavipes Reuter, and Alloeocranum biannulipes Montrouzier & Signoret) and one parasitoid (Dinarmus basalis Rondani) all Coleoptera, Bostrichidae were also identified. The most important traditional practices used to control or prevent insect attack in yam chips were documented and the producers' preference criteria for yam cultivars used to produce chips were identified and prioritized. To further promote the production of yam chips, diversification of insect-resistant yam varieties, conception, and use of health-protective natural insecticides and popularization of modern storage structures were proposed. PMID:23710140

  9. MRS (monitored retrievable storage) Systems Study Task 1 report: Waste management system reliability analysis

    SciTech Connect

    Clark, L.L.; Myers, R.S.

    1989-04-01

    This is one of nine studies undertaken by contractors to the US Department of Energy (DOE), Office of Civilian Radioactive Waste Management (OCRWM), to provide a technical basis for re-evaluating the role of a monitored retrievable storage (MRS) facility. The study evaluates the relative reliabilities of systems with and without an MRS facility using current facility design bases. The principal finding of this report is that the MRS system has several operational advantages that enhance system reliability. These are: (1) the MRS system is likely to encounter fewer technical issues, (2) the MRS would assure adequate system surface storage capacity to accommodate repository construction and startup delays of up to five years or longer if the Nuclear Waste Policy Amendments Act (NWPAA) were amended, (3) the system with an MRS has two federal acceptance facilities with parallel transportation routing and surface storage capacity, and (4) the MRS system would allow continued waste acceptance for up to a year after a major disruption of emplacement operations at the repository.

  10. NDE to Manage Atmospheric SCC in Canisters for Dry Storage of Spent Fuel: An Assessment

    SciTech Connect

    Meyer, Ryan M.; Pardini, Allan F.; Cuta, Judith M.; Adkins, Harold E.; Casella, Andrew M.; Qiao, Hong; Larche, Michael R.; Diaz, Aaron A.; Doctor, Steven R.

    2013-09-01

    This report documents efforts to assess representative horizontal (Transuclear NUHOMS®) and vertical (Holtec HI-STORM) storage systems for the implementation of non-destructive examination (NDE) methods or techniques to manage atmospheric stress corrosion cracking (SCC) in canisters for dry storage of used nuclear fuel. The assessment is conducted by assessing accessibility and deployment, environmental compatibility, and applicability of NDE methods. A recommendation of this assessment is to focus on bulk ultrasonic and eddy current techniques for direct canister monitoring of atmospheric SCC. This assessment also highlights canister regions that may be most vulnerable to atmospheric SCC to guide the use of bulk ultrasonic and eddy current examinations. An assessment of accessibility also identifies canister regions that are easiest and more difficult to access through the ventilation paths of the concrete shielding modules. A conceivable sampling strategy for canister inspections is to sample only the easiest to access portions of vulnerable regions. There are aspects to performing an NDE inspection of dry canister storage system (DCSS) canisters for atmospheric SCC that have not been addressed in previous performance studies. These aspects provide the basis for recommendations of future efforts to determine the capability and performance of eddy current and bulk ultrasonic examinations for atmospheric SCC in DCSS canisters. Finally, other important areas of investigation are identified including the development of instrumented surveillance specimens to identify when conditions are conducive for atmospheric SCC, characterization of atmospheric SCC morphology, and an assessment of air flow patterns over canister surfaces and their influence on chloride deposition.

  11. Environmental safety aspects of the new spent nuclear fuel management and storage system at Ignalina NPP

    SciTech Connect

    Poskas, P.; Ragaisis, V.; Adomaitis, J. E.

    2007-07-01

    In the framework of the preparation for the decommissioning of the Ignalina Nuclear Power Plant (INPP) a new Interim Spent Nuclear Fuel Storage Facility (ISFSF) will be built in the existing sanitary protection zone (SPZ) of INPP. In addition to the ISFSF, the new spent nuclear fuel management activity will include all necessary spent nuclear fuel retrieval and packaging operations at the Reactor Units, transfer of storage casks to the ISFSF, and other activities appropriate to the chosen design solution and required for the safe removal of the existing spent nuclear fuel from storage pools and insertion into the new ISFSF. The Republic of Lithuania regulations require that the average annual dose to the critical group members of population due to operation of nuclear facility shall not exceed dose constraint. If several nuclear facilities are located in the same SPZ, the same dose constraint shall envelope radiological impacts from all operating and planned nuclear facilities. The paper discusses radiological safety assessment aspects as relevant for the new nuclear activity to be implemented in the SPZ of INPP considering specificity of Lithuanian regulatory requirements. The safety assessment methodology aspects, results and conclusions as concern public exposure are outlined and discussed. (authors)

  12. Storage insects on yam chips and their traditional management in Northern Benin.

    PubMed

    Loko, Y L; Dansi, A; Tamo, M; Bokonon-Ganta, A H; Assogba, P; Dansi, M; Vodouhè, R; Akoegninou, A; Sanni, A

    2013-01-01

    Twenty-five villages of Northern Benin were surveyed to identify the constraints of yam chips production, assess the diversity of storage insects on yam chips, and document farmers' perception of their impacts on the stocks and their traditional management practices. Damages due to storage insects (63.9% of responses) and insufficiency of insect-resistant varieties (16.7% of responses) were the major constraints of yam chips production. Twelve insect pest species were identified among which Dinoderus porcellus Lesne (Coleoptera, Bostrichidae) was by far the most important and the most distributed (97.44% of the samples). Three predators (Teretrius nigrescens Lewis, Xylocoris flavipes Reuter, and Alloeocranum biannulipes Montrouzier & Signoret) and one parasitoid (Dinarmus basalis Rondani) all Coleoptera, Bostrichidae were also identified. The most important traditional practices used to control or prevent insect attack in yam chips were documented and the producers' preference criteria for yam cultivars used to produce chips were identified and prioritized. To further promote the production of yam chips, diversification of insect-resistant yam varieties, conception, and use of health-protective natural insecticides and popularization of modern storage structures were proposed. PMID:23710140

  13. Advanced Technologies and Data Management Practices in Environmental Science: Lessons from Academia

    ERIC Educational Resources Information Center

    Hernandez, Rebecca R.; Mayernik, Matthew S.; Murphy-Mariscal, Michelle L.; Allen, Michael F.

    2012-01-01

    Environmental scientists are increasing their capitalization on advancements in technology, computation, and data management. However, the extent of that capitalization is unknown. We analyzed the survey responses of 434 graduate students to evaluate the understanding and use of such advances in the environmental sciences. Two-thirds of the…

  14. Advances in the management of differentiated thyroid cancer with follicular cell strain.

    PubMed

    Ben Slimène, Faouzi; Mhiri, Aida; Ben Ali, Moez; Slimène, Hédia; Ben Raies, Nouzha; Karboua, Esma; Schlumberger, Martin

    2016-03-01

    The management of nodules and thyroid cancer is evolving. The aim is to individualize the treatment, decreasing aggression in the forms low risk and instead seeking new therapeutic options in advanced disease. This update shows the main recent advances in this field. PMID:27575497

  15. Expansion of Michigan EOR Operations Using Advanced Amine Technology at a 600 MW Project Wolverine Carbon Capture and Storage Project

    SciTech Connect

    H Hoffman; Y kishinevsky; S. Wu; R. Pardini; E. Tripp; D. Barnes

    2010-06-16

    Wolverine Power Supply Cooperative Inc, a member owned cooperative utility based in Cadillac Michigan, proposes to demonstrate the capture, beneficial utilization and storage of CO{sub 2} in the expansion of existing Enhanced Oil Recovery operations. This project is being proposed in response to the US Department of Energy Solicitation DE-FOA-0000015 Section III D, 'Large Scale Industrial CCS projects from Industrial Sources' Technology Area 1. The project will remove 1,000 metric tons per day of CO{sub 2} from the Wolverine Clean Energy Venture 600 MW CFB power plant owned and operated by WPC. CO{sub 2} from the flue gas will be captured using Hitachi's CO{sub 2} capture system and advanced amine technology. The capture system with the advanced amine-based solvent supplied by Hitachi is expected to significantly reduce the cost and energy requirements of CO{sub 2} capture compared to current technologies. The captured CO{sub 2} will be compressed and transported for Enhanced Oil Recovery and CO{sub 2} storage purposes. Enhanced Oil Recovery is a proven concept, widely used to recover otherwise inaccessible petroleum reserves. While post-combustion CO{sub 2} capture technologies have been tested at the pilot scale on coal power plant flue gas, they have not yet been demonstrated at a commercial scale and integrated with EOR and storage operations. Amine-based CO{sub 2} capture is the leading technology expected to be available commercially within this decade to enable CCS for utility and industrial facilities firing coal and waste fuels such as petroleum coke. However, traditional CO{sub 2} capture process utilizing commercial amine solvents is very energy intensive for regeneration and is also susceptible to solvent degradation by oxygen as well as SOx and NO{sub 2} in the flue gas, resulting in large operating costs. The large volume of combustion flue gas with its low CO{sub 2} concentration requires large equipment sizes, which together with the highly

  16. Limits, complementarity and improvement of Advanced SAR Interferometry monitoring of anthropogenic subsidence/uplift due to long term CO2 storage

    NASA Astrophysics Data System (ADS)

    de Michele, M.; Raucoules, D.; Rohmer, J.; Loschetter, A.; Raffard, D.; Le Gallo, Y.

    2013-12-01

    A prerequisite to the large scale industrial development of CO2 Capture and geological Storage is the demonstration that the storage is both efficient and safe. In this context, precise uplift/subsidence monitoring techniques constitute a key component of any CO2 storage risk management. Space-borne Differential SAR (Synthetic Aperture Radar) interferometry is a promising monitoring technique. It can provide valuable information on vertical positions of a set of scatterer undergoing surface deformation induced by volumetric changes through time and space caused by CO2 injection in deep aquifers. To what extent ? To date, InSAR techniques have been successfully used in a variety of case-studies involving the measure of surface deformation caused by subsurface fluid withdrawal / injection. For instance, groundwater flow characterization in complex aquifers systems, oil / gas field characterization, verification of enhanced oil recovery efficiency, monitoring of seasonal gas storage. The successful use of InSAR is strictly related to the favourable scattering conditions in terms of spatial distribution of targets and their temporal stability. In arid regions, natural radar scatterers density can be very high, exceeding 1,000 per square km. But future onshore industrial-scale CO2 storage sites are planned in more complex land-covers such as agricultural or vegetated terrains. Those terrains are characterized by poor to moderate radar scatterers density, which decrease the detection limits of the space-borne interferometric technique. The present study discusses the limits and constraints of advanced InSAR techniques applied to deformation measurements associated with CO2 injection/storage into deep aquifers in the presence of agricultural and vegetated land-covers. We explore different options to enhance the measurement performances of InSAR techniques. As a first option, we propose to optimize the deployment of a network of 'artificial' scatterers, i.e. corner

  17. Performance of advanced chromium electrodes for the NASA Redox Energy Storage System

    NASA Technical Reports Server (NTRS)

    Gahn, R. F.; Charleston, J.; Ling, J. S.; Reid, M. A.

    1981-01-01

    Chromium electrodes were prepared for the NASA Redox Storage System with meet the performance requirements for solar-photovoltaic, wind-turbine and electric utility applications. Gold-lead catalyzed carbon felt electrodes up tp 930 sq cm were fabricated and tested in single cells and multicell stacks for hydrogen evolution, coulombic efficiency, catalyst stability and electrochemical activity. Factors which affect the overall performance of a particular electrode include the carbon felt lot, the cleaning treatment and the gold catalyzation method. Effects of the chromium solution chemistry and impurities on charge/discharge performance are also presented.

  18. Quantifying the Operational Benefits of Conventional and Advanced Pumped Storage Hydro on Reliability and Efficiency: Preprint

    SciTech Connect

    Krad, I.; Ela, E.; Koritarov, V.

    2014-07-01

    Pumped storage hydro (PSH) plants have significant potential to provide reliability and efficiency benefits in future electric power systems with high penetrations of variable generation. New PSH technologies, such as adjustable-speed PSH, have been introduced that can also present further benefits. This paper demonstrates and quantifies some of the reliability and efficiency benefits afforded by PSH plants by utilizing the Flexible Energy Scheduling Tool for the Integration of Variable generation (FESTIV), an integrated power system operations tool that evaluates both reliability and production costs.

  19. Advances in membrane technology for the NASA redox energy storage system

    NASA Technical Reports Server (NTRS)

    Ling, J. S.; Charleston, J.

    1980-01-01

    Anion exchange membranes used in the system serve as a charge transferring medium as well as a reactant separator and are the key enabling component in this storage technology. Each membrane formulation undergoes a series of screening tests for area-resistivity, static (non-flow) diffusion rate determination, and performance in Redox systems. The CDIL series of membranes has, by virtue of its chemical stability and high ion exchange capacity, demonstrated superior properties in the redox environment. Additional resistivity results at several acid and iron solution concentrations, iron diffusion rates, and time dependent iron fouling of the various membrane formulations are presented in comparison to past standard formulations.

  20. Advances in the management of chronic thromboembolic pulmonary hypertension.

    PubMed

    Papamatheakis, Demosthenes G; Kim, Nick H

    2015-09-01

    Chronic thromboembolic pulmonary hypertension (CTEPH), a potentially curable form of pulmonary hypertension with pulmonary thromboendarterectomy surgery, has been the focus of significant medical advances. In addition to new imaging modalities that are now used to help recognize and diagnose CTEPH, additional treatment options have emerged for inoperable cases. These include a newly approved medical therapy for inoperable disease or persistent/recurrent CTEPH as well as percutaneous balloon angioplasty of the pulmonary arteries. In this article, we summarize these recent advances in the field and review the related literature. PMID:26239014

  1. C storage in Amazonia pastures, effects of age, climate and management

    NASA Astrophysics Data System (ADS)

    Klumpp, Katja; Stahl, Clement; Blanfort, Vincent; Fontaine, Sebstien; Burban, Benoit; Darsonville, Olivier

    2016-04-01

    The Amazonian region is one of the major C storing areas, with 36-60% of ecosystem C being stored in forest soils. During last decades, more than 15% of Amazonian tropical forest has been converted to pastures. A number of studies provide evidence that soil C stocks of topsoil (0-20 cm) can be higher in grasslands than in native forests after more than 20 years after conversion (e.g. Don et al 2011). As for younger pastures (< 20 years old), results are less evident, showing either an increase or decrease of in topsoil C stock. The absence of a clear pattern was mostly explained due to conjoined changes following deforestation, such as climate conditions and pasture management. Accordingly, the question remains whether tropical permanent pastures can restore soil C stocks after deforestation and what is the capacity of tropical pastures to initiate a recurrent C storage. Pastures are largely affected by agricultural practices, influencing their carbon balance, in interaction with climate effect. In the past 10 years two major droughts (in 2005 and 2010 [2]) were reported for the Amazonian area. A better insight on effects of climatic variability and agricultural management on carbon storage is, thus, valuable to improve/maintain C storage of pastures in tropical regions. Here we like to assess whether tropical permanent pastures i) can restore soil C stocks after deforestation; ii) and to what extend and iii) which role play management practices with respect to climate variability to maintain a recurrent C storage. To establish reliable estimates of soil C storage in Amazonian region, the net C balance of pastures and native forests was quantified by two independent and complementary studies in French Guiana: a chronosequence study including a soil inventory of soil C stocks (0-100 cm depth) in 24 pastures of various ages (i.e. 0 to 42 yrs after deforestation) and 4 native forests, and 5 years of eddy covariance flux measurements (EC) for a young intensively used

  2. Green energy storage materials: advanced nanostructured materials for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Tripathi, Alok Mani; Chandrasekar, M. S.; Mitra, Sagar

    2011-06-01

    The projected doubling of world energy consumption in the next fifty years requires certain measures to meet this demand. The ideal energy provider is reliable, efficient, with low emissions source - wind, solar, etc. The low carbon footprint of renewables is an added benefit, which makes them especially attractive during this era of environmental consciousness. Unfortunately, the intermittent nature of energy from these renewables is not suitable for the commercial and residential grid application, unless the power delivery is 24/7, with minimum fluctuation. This requires intervention of efficient electrical energy storage technology to make power generation from renewable practical. The progress to higher energy and power density especially for battery technology will push material to the edge of stability and yet these materials must be rendered safe, stable and with reliable operation throughout their long life. A major challenge for chemical energy storage is developing the ability to store more energy while maintaining stable electrode-electrolyte interface. A structural transformation occurs during charge-discharge cycle, accompanied by a volume change, degrading the microstructure over-time. The need to mitigate this volume and structural change accompanying charge-discharge cycle necessitates going to nanostructured and multifunctional materials that have the potential of dramatically enhancing the energy density and power density.

  3. A high performance hierarchical storage management system for the Canadian tier-1 centre at TRIUMF

    NASA Astrophysics Data System (ADS)

    Deatrich, D. C.; Liu, S. X.; Tafirout, R.

    2010-04-01

    We describe in this paper the design and implementation of Tapeguy, a high performance non-proprietary Hierarchical Storage Management (HSM) system which is interfaced to dCache for efficient tertiary storage operations. The system has been successfully implemented at the Canadian Tier-1 Centre at TRIUMF. The ATLAS experiment will collect a large amount of data (approximately 3.5 Petabytes each year). An efficient HSM system will play a crucial role in the success of the ATLAS Computing Model which is driven by intensive large-scale data analysis activities that will be performed on the Worldwide LHC Computing Grid infrastructure continuously. Tapeguy is Perl-based. It controls and manages data and tape libraries. Its architecture is scalable and includes Dataset Writing control, a Read-back Queuing mechanism and I/O tape drive load balancing as well as on-demand allocation of resources. A central MySQL database records metadata information for every file and transaction (for audit and performance evaluation), as well as an inventory of library elements. Tapeguy Dataset Writing was implemented to group files which are close in time and of similar type. Optional dataset path control dynamically allocates tape families and assign tapes to it. Tape flushing is based on various strategies: time, threshold or external callbacks mechanisms. Tapeguy Read-back Queuing reorders all read requests by using an elevator algorithm, avoiding unnecessary tape loading and unloading. Implementation of priorities will guarantee file delivery to all clients in a timely manner.

  4. Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations

    DOE Data Explorer

    Buscheck, Thomas A.

    2012-01-01

    Active Management of Integrated Geothermal–CO2 Storage Reservoirs in Sedimentary Formations: An Approach to Improve Energy Recovery and Mitigate Risk : FY1 Final Report The purpose of phase 1 is to determine the feasibility of integrating geologic CO2 storage (GCS) with geothermal energy production. Phase 1 includes reservoir analyses to determine injector/producer well schemes that balance the generation of economically useful flow rates at the producers with the need to manage reservoir overpressure to reduce the risks associated with overpressure, such as induced seismicity and CO2 leakage to overlying aquifers. This submittal contains input and output files of the reservoir model analyses. A reservoir-model "index-html" file was sent in a previous submittal to organize the reservoir-model input and output files according to sections of the FY1 Final Report to which they pertain. The recipient should save the file: Reservoir-models-inputs-outputs-index.html in the same directory that the files: Section2.1.*.tar.gz files are saved in.

  5. Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations

    DOE Data Explorer

    Buscheck, Thomas A.

    2000-01-01

    Active Management of Integrated Geothermal–CO2 Storage Reservoirs in Sedimentary Formations: An Approach to Improve Energy Recovery and Mitigate Risk: FY1 Final Report The purpose of phase 1 is to determine the feasibility of integrating geologic CO2 storage (GCS) with geothermal energy production. Phase 1 includes reservoir analyses to determine injector/producer well schemes that balance the generation of economically useful flow rates at the producers with the need to manage reservoir overpressure to reduce the risks associated with overpressure, such as induced seismicity and CO2 leakage to overlying aquifers. This submittal contains input and output files of the reservoir model analyses. A reservoir-model "index-html" file was sent in a previous submittal to organize the reservoir-model input and output files according to sections of the FY1 Final Report to which they pertain. The recipient should save the file: Reservoir-models-inputs-outputs-index.html in the same directory that the files: Section2.1.*.tar.gz files are saved in.

  6. Methane storage in flexible metal-organic frameworks with intrinsic thermal management.

    PubMed

    Mason, Jarad A; Oktawiec, Julia; Taylor, Mercedes K; Hudson, Matthew R; Rodriguez, Julien; Bachman, Jonathan E; Gonzalez, Miguel I; Cervellino, Antonio; Guagliardi, Antonietta; Brown, Craig M; Llewellyn, Philip L; Masciocchi, Norberto; Long, Jeffrey R

    2015-11-19

    As a cleaner, cheaper, and more globally evenly distributed fuel, natural gas has considerable environmental, economic, and political advantages over petroleum as a source of energy for the transportation sector. Despite these benefits, its low volumetric energy density at ambient temperature and pressure presents substantial challenges, particularly for light-duty vehicles with little space available for on-board fuel storage. Adsorbed natural gas systems have the potential to store high densities of methane (CH4, the principal component of natural gas) within a porous material at ambient temperature and moderate pressures. Although activated carbons, zeolites, and metal-organic frameworks have been investigated extensively for CH4 storage, there are practical challenges involved in designing systems with high capacities and in managing the thermal fluctuations associated with adsorbing and desorbing gas from the adsorbent. Here, we use a reversible phase transition in a metal-organic framework to maximize the deliverable capacity of CH4 while also providing internal heat management during adsorption and desorption. In particular, the flexible compounds Fe(bdp) and Co(bdp) (bdp(2-) = 1,4-benzenedipyrazolate) are shown to undergo a structural phase transition in response to specific CH4 pressures, resulting in adsorption and desorption isotherms that feature a sharp 'step'. Such behaviour enables greater storage capacities than have been achieved for classical adsorbents, while also reducing the amount of heat released during adsorption and the impact of cooling during desorption. The pressure and energy associated with the phase transition can be tuned either chemically or by application of mechanical pressure. PMID:26503057

  7. Methane storage in flexible metal-organic frameworks with intrinsic thermal management

    NASA Astrophysics Data System (ADS)

    Mason, Jarad A.; Oktawiec, Julia; Taylor, Mercedes K.; Hudson, Matthew R.; Rodriguez, Julien; Bachman, Jonathan E.; Gonzalez, Miguel I.; Cervellino, Antonio; Guagliardi, Antonietta; Brown, Craig M.; Llewellyn, Philip L.; Masciocchi, Norberto; Long, Jeffrey R.

    2015-11-01

    As a cleaner, cheaper, and more globally evenly distributed fuel, natural gas has considerable environmental, economic, and political advantages over petroleum as a source of energy for the transportation sector. Despite these benefits, its low volumetric energy density at ambient temperature and pressure presents substantial challenges, particularly for light-duty vehicles with little space available for on-board fuel storage. Adsorbed natural gas systems have the potential to store high densities of methane (CH4, the principal component of natural gas) within a porous material at ambient temperature and moderate pressures. Although activated carbons, zeolites, and metal-organic frameworks have been investigated extensively for CH4 storage, there are practical challenges involved in designing systems with high capacities and in managing the thermal fluctuations associated with adsorbing and desorbing gas from the adsorbent. Here, we use a reversible phase transition in a metal-organic framework to maximize the deliverable capacity of CH4 while also providing internal heat management during adsorption and desorption. In particular, the flexible compounds Fe(bdp) and Co(bdp) (bdp2- = 1,4-benzenedipyrazolate) are shown to undergo a structural phase transition in response to specific CH4 pressures, resulting in adsorption and desorption isotherms that feature a sharp ‘step’. Such behaviour enables greater storage capacities than have been achieved for classical adsorbents, while also reducing the amount of heat released during adsorption and the impact of cooling during desorption. The pressure and energy associated with the phase transition can be tuned either chemically or by application of mechanical pressure.

  8. Managing the cultivation and processing of microalgae to prolong storage in water-in-oil emulsions.

    PubMed

    Fernández, Lorena; Cheng, Yu-Shen; Scher, Herbert; VanderGheynst, Jean S

    2014-06-01

    Producing biofuel from microalgae on a large scale will require high biomass productivity using systems such as high-rate raceway ponds. The vast scale of proposed raceway ponds, spanning 247 to 988 acres per farm, suggests practices currently used in commercial monoculture agricultural systems will need to be adopted for cultivation of algae. In commercial crop production, monoculture is facilitated by a well-established seed production, distribution, and delivery system. Currently, no such system exists for microalgae. The aims of this study were to investigate the application of water-in-oil (W/O) emulsions for the storage of microalgae and the management steps required to prolong cell viability. Water-in-oil emulsions were prepared with Chlorella sorokiniana, C. minutissima, C. vulgaris var. vulgaris, and C. vulgaris to investigate the impacts of cell cultivation medium and cell acclimation prior to emulsification on cell viability during storage. For emulsions prepared with C. sorokiniana, cells that received an acclimation treatment 24 h between cell separation from the cultivation medium and emulsification survived over 100 days longer than cells that did not receive an acclimation treatment. Emulsions prepared with C. sorokiniana grown in medium containing 29.7 mM KNO3, 1.66 mM MgSO4 · 7H2O, and 0.85 mM FeSO4 · 2H2O had higher levels of viable cells after 100 days of storage compared to cells grown in medium containing 9.90 mM KNO3 and 0.20 mM MgSO4 · 7H2O with no FeSO4 · 2H2O. The results indicate that processing of cells can be managed to increase the stability of microalgae in W/O emulsions. PMID:24682481

  9. 41 CFR 302-9.12 - May I receive an advance of funds for transportation and emergency or temporary storage of my POV?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false May I receive an advance... PRIVATELY OWNED VEHICLE General Rules § 302-9.12 May I receive an advance of funds for transportation...

  10. Role of chemotherapy in the management of advanced thymic tumors.

    PubMed

    Evans, Tracey L; Lynch, Thomas J

    2005-01-01

    Chemotherapy has an important role in the treatment of advanced thymic tumors. Early stage tumors are successfully treated with surgery. Locally advanced tumors (Masaoka stage III and IVA) are often treated with combined modality treatment including surgery, radiation, and chemotherapy. For patients with curable thymic tumors, the ability to attain a complete resection is a critical prognostic factor. Locally advanced tumors have a relatively high risk of recurrence and decreased rates of long-term survival. A multimodality approach including induction chemotherapy and postoperative radiation therapy can improve complete resection rates and long-term outcomes. Thymic tumors are chemoresponsive with optimal responses achieved with cisplatin-based combination chemotherapy. Chemotherapy with radiation can result in long-term progression-free survival for patients with locally advanced disease who remain inoperable following induction therapy. Patients with disseminated (stage IVB) thymic tumors can also have significant disease response and palliation of symptoms when treated with chemotherapy. Octreotide and corticosteroids also have shown efficacy. For best results, it is important that thoracic surgeons, radiation oncologists, and medical oncologists work together to obtain the best local control of tumor and optimal treatment of metastases. PMID:16104360

  11. Factors Preventing Women's Advancement in Management in Turkey

    ERIC Educational Resources Information Center

    Sanal, Mustafa

    2008-01-01

    This article examines the reasons why there is relatively very small number of woman administrators in public and private sector in Turkey. We have tried to reveal the factors preventing women's advancement up the organizational ladder. Although there are no legal obstacles against woman administrators in Turkey, such factors as gender…

  12. Advanced techniques for the storage and use of very large, heterogeneous spatial databases

    NASA Technical Reports Server (NTRS)

    Peuquet, Donna J.

    1987-01-01

    Progress is reported in the development of a prototype knowledge-based geographic information system. The overall purpose of this project is to investigate and demonstrate the use of advanced methods in order to greatly improve the capabilities of geographic information system technology in the handling of large, multi-source collections of spatial data in an efficient manner, and to make these collections of data more accessible and usable for the Earth scientist.

  13. Technical Support Document: The Development of the Advanced Energy Design Guide for Small Warehouse and Self-Storage Buildings

    SciTech Connect

    Liu, Bing; Jarnagin, Ronald E.; Jiang, Wei; Gowri, Krishnan

    2007-12-01

    This Technical Support Document (TSD) describes the process and methodology for development of the Advanced Energy Design Guide for Small Warehouse and Self-storage Buildings (AEDG-WH or the Guide), a design guidance document intended to provide recommendations for achieving 30% energy savings in small warehouses over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-WH is the fourth in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA), the United States Green Buildings Council (USGBC), and the U.S. Department of Energy (DOE).

  14. Recent advances in metal oxide-based electrode architecture design for electrochemical energy storage.

    PubMed

    Jiang, Jian; Li, Yuanyuan; Liu, Jinping; Huang, Xintang; Yuan, Changzhou; Lou, Xiong Wen David

    2012-10-01

    Metal oxide nanostructures are promising electrode materials for lithium-ion batteries and supercapacitors because of their high specific capacity/capacitance, typically 2-3 times higher than that of the carbon/graphite-based materials. However, their cycling stability and rate performance still can not meet the requirements of practical applications. It is therefore urgent to improve their overall device performance, which depends on not only the development of advanced electrode materials but also in a large part "how to design superior electrode architectures". In the article, we will review recent advances in strategies for advanced metal oxide-based hybrid nanostructure design, with the focus on the binder-free film/array electrodes. These binder-free electrodes, with the integration of unique merits of each component, can provide larger electrochemically active surface area, faster electron transport and superior ion diffusion, thus leading to substantially improved cycling and rate performance. Several recently emerged concepts of using ordered nanostructure arrays, synergetic core-shell structures, nanostructured current collectors, and flexible paper/textile electrodes will be highlighted, pointing out advantages and challenges where appropriate. Some future electrode design trends and directions are also discussed. PMID:22912066

  15. Recent advances in applying decision science to managing national forests

    USGS Publications Warehouse

    Marcot, Bruce G.; Thompson, Matthew P.; Runge, Michael C.; Thompson, Frank R.; McNulty, Steven; Cleaves, David; Tomosy, Monica; Fisher, Larry A.; Andrew, Bliss

    2012-01-01

    Management of federal public forests to meet sustainability goals and multiple use regulations is an immense challenge. To succeed, we suggest use of formal decision science procedures and tools in the context of structured decision making (SDM). SDM entails four stages: problem structuring (framing the problem and defining objectives and evaluation criteria), problem analysis (defining alternatives, evaluating likely consequences, identifying key uncertainties, and analyzing tradeoffs), decision point (identifying the preferred alternative), and implementation and monitoring the preferred alternative with adaptive management feedbacks. We list a wide array of models, techniques, and tools available for each stage, and provide three case studies of their selected use in National Forest land management and project plans. Successful use of SDM involves participation by decision-makers, analysts, scientists, and stakeholders. We suggest specific areas for training and instituting SDM to foster transparency, rigor, clarity, and inclusiveness in formal decision processes regarding management of national forests.

  16. Emerging technological and cultural shifts advancing drylands research and management

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sustainable provisioning of ecosystem services in dryland landscapes is complicated by extreme conditions that constrain biological responses to perturbation, vast spatial and temporal complexity, and uncertainty regarding the resilience of these ecosystems to management practices and climate change...

  17. Simulation-based design of energy management system with storage battery for a refugee shelter in Japan

    SciTech Connect

    Kaji, K.; Zhang, J.; Horie, H.; Tanaka, K.; Akimoto, H.

    2013-12-10

    Since the massive earthquake hit eastern Japan in March, 2011, our team has participated in the recovery planning for Kesen Association, which is a group of cities in northeastern Japan. As one of our proposals for the recovery planning for the community, we are designing energy management system with renewable energy (RE) and storage batteries. Some public facilities in the area have been used as refugee shelters, but refugees had to put up with life without electricity for a while after the disaster. If RE generator and storage batteries are introduced into the facilities, it is possible to provide refugees with electricity. In this study, the sizes of photovoltaic (PV) appliances and storage batteries to be introduced into one public facility are optimized. The optimization is based on simulation, in which electric energy is managed by charge and discharge of storage battery.

  18. Simulation-based design of energy management system with storage battery for a refugee shelter in Japan

    NASA Astrophysics Data System (ADS)

    Kaji, K.; Zhang, J.; Horie, H.; Akimoto, H.; Tanaka, K.

    2013-12-01

    Since the massive earthquake hit eastern Japan in March, 2011, our team has participated in the recovery planning for Kesen Association, which is a group of cities in northeastern Japan. As one of our proposals for the recovery planning for the community, we are designing energy management system with renewable energy (RE) and storage batteries. Some public facilities in the area have been used as refugee shelters, but refugees had to put up with life without electricity for a while after the disaster. If RE generator and storage batteries are introduced into the facilities, it is possible to provide refugees with electricity. In this study, the sizes of photovoltaic (PV) appliances and storage batteries to be introduced into one public facility are optimized. The optimization is based on simulation, in which electric energy is managed by charge and discharge of storage battery.

  19. Knowledge Management Initiatives Used to Maintain Regulatory Expertise in Transportation and Storage of Radioactive Materials - 12177

    SciTech Connect

    Lindsay, Haile; Garcia-Santos, Norma; Saverot, Pierre; Day, Neil; Gambone Rodriguez, Kimberly; Cruz, Luis; Sotomayor-Rivera, Alexis; Vechioli, Lucieann; Vera, John; Pstrak, David

    2012-07-01

    The U.S. Nuclear Regulatory Commission (NRC) was established in 1974 with the mission to license and regulate the civilian use of nuclear materials for commercial, industrial, academic, and medical uses in order to protect public health and safety, and the environment, and promote the common defense and security. Currently, approximately half (∼49%) of the workforce at the NRC has been with the Agency for less than six years. As part of the Agency's mission, the NRC has partial responsibility for the oversight of the transportation and storage of radioactive materials. The NRC has experienced a significant level of expertise leaving the Agency due to staff attrition. Factors that contribute to this attrition include retirement of the experienced nuclear workforce and mobility of staff within or outside the Agency. Several knowledge management (KM) initiatives have been implemented within the Agency, with one of them including the formation of a Division of Spent Fuel Storage and Transportation (SFST) KM team. The team, which was formed in the fall of 2008, facilitates capturing, transferring, and documenting regulatory knowledge for staff to effectively perform their safety oversight of transportation and storage of radioactive materials, regulated under Title 10 of the Code of Federal Regulations (10 CFR) Part 71 and Part 72. In terms of KM, the SFST goal is to share critical information among the staff to reduce the impact from staff's mobility and attrition. KM strategies in place to achieve this goal are: (1) development of communities of practice (CoP) (SFST Qualification Journal and the Packaging and Storing Radioactive Material) in the on-line NRC Knowledge Center (NKC); (2) implementation of a SFST seminar program where the seminars are recorded and placed in the Agency's repository, Agency-wide Documents Access and Management System (ADAMS); (3) meeting of technical discipline group programs to share knowledge within specialty areas; (4) development of

  20. Pakistan-Specific Cases for the Advanced Management Course in Public Administration.

    ERIC Educational Resources Information Center

    McLean, Gary N., Ed.

    A compilation of management case studies concerning public administration in Pakistan and accompanying teaching notes, this document is intended to foster discussion in classes such as the advanced management course in public administration at the National Institute of Public Administration in Lahore, Pakistan. Included are case studies entitled…

  1. Technology assessments of advanced energy storage systems for electric and hybrid vehicles

    SciTech Connect

    Not Available

    1993-04-30

    Flywheels, hydropneumatic accumulators (in vehicles with a hydrostatic powertrain), and superconducting magnets were assessed as candidate technologies for recovering braking energy and averaging power demands in electric and hybrid vehicles. The technologies were also assessed for their suitability for fulfilling the entire energy storage requirement in vehicles. The scope of the technology assessments included the current state-of-the-art and developments anticipated within the next few years in the US and abroad. Key individuals and companies currently working on each technology contributed technical information to the study. Some of these individuals and companies are nearing the pre-production prototype stage with systems suitable for automobiles. Several have constructed systems using similar technology for other applications, including satellites and industrial equipment.

  2. Advances in the Diagnosis and Management of Inflammatory Bowel Disease: Challenges and Uncertainties

    PubMed Central

    Mosli, Mahmoud; Al Beshir, Mohammad; Al-Judaibi, Bandar; Al-Ameel, Turki; Saleem, Abdulaziz; Bessissow, Talat; Ghosh, Subrata; Almadi, Majid

    2014-01-01

    Over the past two decades, several advances have been made in the management of patients with inflammatory bowel disease (IBD) from both evaluative and therapeutic perspectives. This review discusses the medical advancements that have recently been made as the standard of care for managing patients with ulcerative colitis (UC) and Crohn's Disease (CD) and to identify the challenges associated with implementing their use in clinical practice. A comprehensive literature search of the major databases (PubMed and Embase) was conducted for all recent scientific papers (1990–2013) giving the recent updates on the management of IBD and the data were extracted. The reported advancements in managing IBD range from diagnostic and evaluative tools, such as genetic tests, biochemical surrogate markers of activity, endoscopic techniques, and radiological modalities, to therapeutic advances, which encompass medical, endoscopic, and surgical interventions. There are limited studies addressing the cost-effectiveness and the impact that these advances have had on medical practice. The majority of the advances developed for managing IBD, while considered instrumental by some IBD experts in improving patient care, have questionable applications due to constraints of cost, lack of availability, and most importantly, insufficient evidence that supports their role in improving important long-term health-related outcomes. PMID:24705146

  3. Limited opportunities for management-induced soil carbon storage in New South Wales, Australia.

    NASA Astrophysics Data System (ADS)

    Wilson, Brian; Lonergan, Vanessa

    2013-04-01

    Soil management has been promoted internationally and in Australia as a means of storing additional soil carbon to offset greenhouse gas emissions (GHG) elsewhere. Despite considerable investment in research in Australia, difficulties with reliable detection and estimation of soil carbon change remain as significant barriers to soil carbon accounting and trading. Here we present examples from an extensive dataset across the diverse production landscapes of New South Wales, Australia generated from both the NSW Statewide Soil Monitoring Program and the National Soil Carbon Research Program. Issues relating to climate, spatial variability, historical and contemporary land-management are highlighted to illustrate the challenges of detecting and estimating management-induced soil carbon change. We further demonstrate that, where it is possible to detect soil carbon change resulting from agricultural management, the quantities stored are unlikely to make a significant contribution to reductions in net greenhouse gas emissions. Historical factors and non-agricultural land-use options are likely to provide more significant potential for long-term soil carbon storage in this environment.

  4. Advanced Flow Control as a Management Tool in the National Airspace System

    NASA Technical Reports Server (NTRS)

    Wugalter, S.

    1974-01-01

    Advanced Flow Control is closely related to Air Traffic Control. Air Traffic Control is the business of the Federal Aviation Administration. To formulate an understanding of advanced flow control and its use as a management tool in the National Airspace System, it becomes necessary to speak somewhat of air traffic control, the role of FAA, and their relationship to advanced flow control. Also, this should dispell forever, any notion that advanced flow control is the inspirational master valve scheme to be used on the Alaskan Oil Pipeline.

  5. HEATS: Thermal Energy Storage

    SciTech Connect

    2012-01-01

    HEATS Project: The 15 projects that make up ARPA-E’s HEATS program, short for “High Energy Advanced Thermal Storage,” seek to develop revolutionary, cost-effective ways to store thermal energy. HEATS focuses on 3 specific areas: 1) developing high-temperature solar thermal energy storage capable of cost-effectively delivering electricity around the clock and thermal energy storage for nuclear power plants capable of cost-effectively meeting peak demand, 2) creating synthetic fuel efficiently from sunlight by converting sunlight into heat, and 3) using thermal energy storage to improve the driving range of electric vehicles (EVs) and also enable thermal management of internal combustion engine vehicles.

  6. Integrated Vehicle Thermal Management for Advanced Vehicle Propulsion Technologies

    SciTech Connect

    Bennion, K.; Thornton, M.

    2010-04-01

    A critical element to the success of new propulsion technologies that enable reductions in fuel use is the integration of component thermal management technologies within a viable vehicle package. Vehicle operation requires vehicle thermal management systems capable of balancing the needs of multiple vehicle systems that may require heat for operation, require cooling to reject heat, or require operation within specified temperature ranges. As vehicle propulsion transitions away from a single form of vehicle propulsion based solely on conventional internal combustion engines (ICEs) toward a wider array of choices including more electrically dominant systems such as plug-in hybrid electric vehicles (PHEVs), new challenges arise associated with vehicle thermal management. As the number of components that require active thermal management increase, so do the costs in terms of dollars, weight, and size. Integrated vehicle thermal management is one pathway to address the cost, weight, and size challenges. The integration of the power electronics and electric machine (PEEM) thermal management with other existing vehicle systems is one path for reducing the cost of electric drive systems. This work demonstrates techniques for evaluating and quantifying the integrated transient and continuous heat loads of combined systems incorporating electric drive systems that operate primarily under transient duty cycles, but the approach can be extended to include additional steady-state duty cycles typical for designing vehicle thermal management systems of conventional vehicles. The work compares opportunities to create an integrated low temperature coolant loop combining the power electronics and electric machine with the air conditioning system in contrast to a high temperature system integrated with the ICE cooling system.

  7. Advances in remote sensing for vegetation dynamics and agricultural management

    NASA Astrophysics Data System (ADS)

    Tucker, C. J.; Puma, M. J.

    2015-12-01

    Spaceborne remote sensing has led to great advances in the global monitoring of vegetation. For example, the NASA Global Inventory Modeling and Mapping Studies (GIMMS) group has developed widely used datasets from the Advanced Very High Resolution Radiometer (AVHRR) sensors as well as the Moderate Resolution Imaging Spectroradiometer (MODIS) map imagery and normalized difference vegetation index datasets. These data are valuable for analyzing vegetation trends and variability at the regional and global levels. Numerous studies have investigated such trends and variability for both natural vegetation (e.g., re-greening of the Sahel, shifts in the Eurasian boreal forest, Amazonian drought sensitivity) and crops (e.g., impacts of extremes on agricultural production). Here, a critical overview is presented on recent developments and opportunities in the use of remote sensing for monitoring vegetation and crop dynamics.

  8. Advances in Remote Sensing for Vegetation Dynamics and Agricultural Management

    NASA Technical Reports Server (NTRS)

    Tucker, Compton; Puma, Michael

    2015-01-01

    Spaceborne remote sensing has led to great advances in the global monitoring of vegetation. For example, the NASA Global Inventory Modeling and Mapping Studies (GIMMS) group has developed widely used datasets from the Advanced Very High Resolution Radiometer (AVHRR) sensors as well as the Moderate Resolution Imaging Spectroradiometer (MODIS) map imagery and normalized difference vegetation index datasets. These data are valuable for analyzing vegetation trends and variability at the regional and global levels. Numerous studies have investigated such trends and variability for both natural vegetation (e.g., re-greening of the Sahel, shifts in the Eurasian boreal forest, Amazonian drought sensitivity) and crops (e.g., impacts of extremes on agricultural production). Here, a critical overview is presented on recent developments and opportunities in the use of remote sensing for monitoring vegetation and crop dynamics.

  9. Management of Advanced-Phase Chronic Myelogenous Leukemia.

    PubMed

    Radich, Jerald P

    2016-05-01

    Chronic myelogenous leukemia represents the poster child of successful precision medicine in cancer, with amazing survival results achieved with targeted tyrosine kinase inhibitors (TKIs) in many patients with chronic-phase disease. Unfortunately, however, this good news has not extended to patients in blast crisis, for whom survival has not clearly been improved with TKIs. During his presentation at the NCCN 21st Annual Conference, Jerald P. Radich, MD, briefly explored the biology behind advanced-stage disease and several of the molecular findings in disease progression. He also reviewed some of the therapeutic options in advanced disease, emphasizing that transplantation, although fraught with some difficulties, offers the best long-term prognosis for patients in blast crisis. PMID:27226510

  10. Major advances in managing community-acquired pneumonia

    PubMed Central

    Asrar Khan, Waseem

    2013-01-01

    This article is a non-systematic review of selected recent publications in community-acquired pneumonia, including a comparison of various guidelines. Risk stratification of patients has recently been advanced by the addition of several useful biomarkers. The issue of single versus dual antibiotic treatment remains controversial and awaits a conclusive randomized controlled trial. However, in the meantime, there is a working consensus that more severe patients should receive dual therapy. PMID:24167724

  11. Endoscopy and polyps-diagnostic and therapeutic advances in management

    PubMed Central

    Steele, Scott R; Johnson, Eric K; Champagne, Bradley; Davis, Brad; Lee, Sang; Rivadeneira, David; Ross, Howard; Hayden, Dana A; Maykel, Justin A

    2013-01-01

    Despite multiple efforts aimed at early detection through screening, colon cancer remains the third leading cause of cancer-related deaths in the United States, with an estimated 51000 deaths during 2013 alone. The goal remains to identify and remove benign neoplastic polyps prior to becoming invasive cancers. Polypoid lesions of the colon vary widely from hyperplastic, hamartomatous and inflammatory to neoplastic adenomatous growths. Although these lesions are all benign, they are common, with up to one-quarter of patients over 60 years old will develop pre-malignant adenomatous polyps. Colonoscopy is the most effective screening tool to detect polyps and colon cancer, although several studies have demonstrated missed polyp rates from 6%-29%, largely due to variations in polyp size. This number can be as high as 40%, even with advanced (> 1 cm) adenomas. Other factors including sub-optimal bowel preparation, experience of the endoscopist, and patient anatomical variations all affect the detection rate. Additional challenges in decision-making exist when dealing with more advanced, and typically larger, polyps that have traditionally required formal resection. In this brief review, we will explore the recent advances in polyp detection and therapeutic options. PMID:23885138

  12. Advancing Information Technology in the Waste Management World

    SciTech Connect

    Slater, B.; Smylie, G.; Thompson, S.; Bruemmer, H.

    2008-07-01

    The development and utilization of software for the waste management world is critical, yet complex. Numerous and sometimes conflicting regulations, coupled with demands for streamlined efficiency and high standards of safety, require innovative information technology solutions and closely-managed processes. The primary goal of this paper is to demonstrate how this challenge can be met by applying software engineering best practices to the waste management domain. This paper presents two case studies highlighting how IEEE (Institute of Electrical and Electronics Engineers) software engineering standards have proven to be effective within the CH-TRU and RH-TRU waste management arena. These examples show how adherence to best practices has enabled software to meet institutional expectations for usability, consistency, reusability, documentation, quality assurance, and adherence to regulations. Specific techniques, such as the use of customisable software life-cycle management software, and the integration of subject matter experts and the information technology specialists through the change control board, will be presented in detail. With an eye to the future, we will show the software resulting from a best practices approach can be further enhanced with the use of artificial intelligence techniques to tackle problems such as accounting for unexpected user inputs, analyzing the relationship between data fields, and recognizing aberrant patterns in the data. (authors)

  13. [Advances in low impact development technology for urban stormwater management].

    PubMed

    Liu, Wen; Chen, Wei-ping; Peng, Chi

    2015-06-01

    Low impact development ( LID), as an innovative technology for stormwater management, is effective to mitigate urban flooding and to detain pollutants. This paper systemically introduced the LID technology system, and summarized the reduction effects of three typical LID facilities (i.e. , bio-retention, green roof and permeable pavement) on stormwater runoff and main pollutants in recent literature, as well as research outcomes and experiences of LID technology on model simulation, cost-benefit analysis and management system. On this basis, we analyzed the problems and limitations of current LID technology studies. Finally, some suggestions about future research directions, appropriate design and scientific management were put forth. This work intended to provide scientific basis and suggestions for widespread use and standard setting of LID technology in China by referencing overseas studies. PMID:26572048

  14. Clinical Management of Pain in Advanced Lung Cancer

    PubMed Central

    Simmons, Claribel P.L.; MacLeod, Nicholas; Laird, Barry J.A.

    2012-01-01

    Lung cancer is the most common cancer in the world and pain is its most common symptom. Pain can be brought about by several different causes including local effects of the tumor, regional or distant spread of the tumor, or from anti-cancer treatment. Patients with lung cancer experience more symptom distress than patients with other types of cancer. Symptoms such as pain may be associated with worsening of other symptoms and may affect quality of life. Pain management adheres to the principles set out by the World Health Organization’s analgesic ladder along with adjuvant analgesics. As pain can be caused by multiple factors, its treatment requires pharmacological and non-pharmacological measures from a multidisciplinary team linked in with specialist palliative pain management. This review article examines pain management in lung cancer. PMID:23115483

  15. Advanced information management tools for investigation and case management support in a networked heterogeneous computing environment

    NASA Astrophysics Data System (ADS)

    Clifton, T. E., III; Lehrer, Nancy; Klopfenstein, Mark; Hoshstrasser, Belinda; Campbell, Rachel

    1997-02-01

    The right information, at the right time and place, is key to successful law enforcement. The information exists; the challenge is in getting the information to the law enforcement professionals in a usable form, when they need it. Over the last year, the authors have applied advanced information management technologies towards addressing this challenge, in concert with a complementary research effort in secure wireless network technology by SRI International. The goal of the combined efforts is to provide law enforcement professionals the ability to access a wide range of heterogeneous and legacy data sources (structured, as well as free text); process information into digital multimedia case folders; and create World Wide Web-based multimedia products, accessible by selected field investigators via Fortezza-enhanced secure web browsers over encrypted wireless communications. We discuss the results of our knowledge acquisition activities at federal, regional, and local law enforcement organizations; our technical solution; results of the one year development and demonstration effort; and plans for future research.

  16. Magnitude of anthropogenic phosphorus storage in the agricultural production and the waste management systems at the regional and country scales.

    PubMed

    Chowdhury, Rubel Biswas; Chakraborty, Priyanka

    2016-08-01

    Based on a systematic review of 17 recent substance flow analyses of phosphorus (P) at the regional and country scales, this study presents an assessment of the magnitude of anthropogenic P storage in the agricultural production and the waste management systems to identify the potential for minimizing unnecessary P storage to reduce the input of P as mineral fertilizer and the loss of P. The assessment indicates that in case of all (6) P flow analyses at the regional scale, the combined mass of annual P storage in the agricultural production and the waste management systems is greater than 50 % of the mass of annual P inflow as mineral fertilizer in the agricultural production system, while this is close to or more than 100 % in case of half of these analyses. At the country scale, in case of the majority (7 out of 11) of analyses, the combined mass of annual P storage in the agricultural production and the waste management systems has been found to be roughly equivalent or greater than 100 % of the mass of annual P inflow as mineral fertilizer in the agricultural production system, while it ranged from 30 to 60 % in the remaining analyses. A simple scenario analysis has revealed that the annual storage of P in this manner over 100 years could result in the accumulation of a massive amount of P in the agricultural production and the waste management systems at both the regional and country scales. This study suggests that sustainable P management initiatives at the regional and country scales should put more emphasis on minimizing unwanted P storage in the agricultural production and the waste management systems. PMID:27278065

  17. Advanced reservoir management for independent oil and gas producers

    SciTech Connect

    Sgro, A.G.; Kendall, R.P.; Kindel, J.M.; Webster, R.B.; Whitney, E.M.

    1996-11-01

    There are more than fifty-two hundred oil and gas producers operating in the United States today. Many of these companies have instituted improved oil recovery programs in some form, but very few have had access to state-of-the-art modeling technologies routinely used by major producers to manage these projects. Since independent operators are playing an increasingly important role in the production of hydrocarbons in the United States, it is important to promote state-of-the-art management practices, including the planning and monitoring of improved oil recovery projects, within this community. This is one of the goals of the Strategic Technologies Council, a special interest group of independent oil and gas producers. Reservoir management technologies have the potential to increase oil recovery while simultaneously reducing production costs. These technologies were pioneered by major producers and are routinely used by them. Independent producers confront two problems adopting this approach: the high cost of acquiring these technologies and the high cost of using them even if they were available. Effective use of reservoir management tools requires, in general, the services of a professional (geoscientist or engineer) who is already familiar with the details of setting up, running, and interpreting computer models.

  18. Recent advances in nanostructured Nb-based oxides for electrochemical energy storage

    NASA Astrophysics Data System (ADS)

    Yan, Litao; Rui, Xianhong; Chen, Gen; Xu, Weichuan; Zou, Guifu; Luo, Hongmei

    2016-04-01

    For the past five years, nanostructured niobium-based oxides have emerged as one of the most prominent materials for batteries, supercapacitors, and fuel cell technologies, for instance, TiNb2O7 as an anode for lithium-ion batteries (LIBs), Nb2O5 as an electrode for supercapacitors (SCs), and niobium-based oxides as chemically stable electrochemical supports for fuel cells. Their high potential window can prevent the formation of lithium dendrites, and their rich redox chemistry (Nb5+/Nb4+, Nb4+/Nb3+) makes them very promising electrode materials. Their unique chemical stability under acid conditions is favorable for practical fuel-cell operation. In this review, we summarized recent progress made concerning the use of niobium-based oxides as electrodes for batteries (LIBs, sodium-ion batteries (SIBs), and vanadium redox flow batteries (VRBs)), SCs, and fuel cell applications. Moreover, crystal structures, charge storage mechanisms in different crystal structures, and electrochemical performances in terms of the specific capacitance/capacity, rate capability, and cycling stability of niobium-based oxides are discussed. Insights into the future research and development of niobium-based oxide compounds for next-generation electrochemical devices are also presented. We believe that this review will be beneficial for research scientists and graduate students who are searching for promising electrode materials for batteries, SCs, and fuel cells.

  19. Recent advances in nanostructured Nb-based oxides for electrochemical energy storage.

    PubMed

    Yan, Litao; Rui, Xianhong; Chen, Gen; Xu, Weichuan; Zou, Guifu; Luo, Hongmei

    2016-04-28

    For the past five years, nanostructured niobium-based oxides have emerged as one of the most prominent materials for batteries, supercapacitors, and fuel cell technologies, for instance, TiNb2O7 as an anode for lithium-ion batteries (LIBs), Nb2O5 as an electrode for supercapacitors (SCs), and niobium-based oxides as chemically stable electrochemical supports for fuel cells. Their high potential window can prevent the formation of lithium dendrites, and their rich redox chemistry (Nb(5+)/Nb(4+), Nb(4+)/Nb(3+)) makes them very promising electrode materials. Their unique chemical stability under acid conditions is favorable for practical fuel-cell operation. In this review, we summarized recent progress made concerning the use of niobium-based oxides as electrodes for batteries (LIBs, sodium-ion batteries (SIBs), and vanadium redox flow batteries (VRBs)), SCs, and fuel cell applications. Moreover, crystal structures, charge storage mechanisms in different crystal structures, and electrochemical performances in terms of the specific capacitance/capacity, rate capability, and cycling stability of niobium-based oxides are discussed. Insights into the future research and development of niobium-based oxide compounds for next-generation electrochemical devices are also presented. We believe that this review will be beneficial for research scientists and graduate students who are searching for promising electrode materials for batteries, SCs, and fuel cells. PMID:27074412

  20. Batteries: An Advanced Na-FeCl2 ZEBRA Battery for Stationary Energy Storage Application

    SciTech Connect

    Li, Guosheng; Lu, Xiaochuan; Kim, Jin Yong; Viswanathan, Vilayanur V.; Meinhardt, Kerry D.; Engelhard, Mark H.; Sprenkle, Vincent L.

    2015-06-17

    Sodium-metal chloride batteries, ZEBRA, are considered as one of the most important electrochemical devices for stationary energy storage applications because of its advantages of good cycle life, safety, and reliability. However, sodium-nickel chloride (Na-NiCl2) batteries, the most promising redox chemistry in ZEBRA batteries, still face great challenges for the practical application due to its inevitable feature of using Ni cathode (high materials cost). In this work, a novel intermediate-temperature sodium-iron chloride (Na-FeCl2) battery using a molten sodium anode and Fe cathode is proposed and demonstrated. The first use of unique sulfur-based additives in Fe cathode enables Na-FeCl2 batteries can be assembled in the discharged state and operated at intermediate-temperature (<200°C). The results in this work demonstrate that intermediate-temperature Na-FeCl2 battery technology could be a propitious solution for ZEBRA battery technologies by replacing the traditional Na-NiCl2 chemistry.

  1. Rethinking hyporheic flow and transient storage to advance understanding of stream-catchment connections

    USGS Publications Warehouse

    Bencala, K.E.; Gooseff, M.N.; Kimball, B.A.

    2011-01-01

    Although surface water and groundwater are increasingly referred to as one resource, there remain environmental and ecosystem needs to study the 10 m to 1 km reach scale as one hydrologic system. Streams gain and lose water over a range of spatial and temporal scales. Large spatial scales (kilometers) have traditionally been recognized and studied as river-aquifer connections. Over the last 25 years hyporheic exchange flows (1-10 m) have been studied extensively. Often a transient storage model has been used to quantify the physical solute transport setting in which biogeochemical processes occur. At the longer 10 m to 1 km scale of stream reaches it is now clear that streams which gain water overall can coincidentally lose water to the subsurface. At this scale, the amounts of water transferred are not necessarily significant but the exchanges can, however, influence solute transport. The interpretation of seemingly straightforward questions about water, contaminant, and nutrient fluxes into and along a stream can be confounded by flow losses which are too small to be apparent in stream gauging and along flow paths too long to be detected in tracer experiments. We suggest basic hydrologic approaches, e.g., measurement of flow along the channel, surface and subsurface solute sampling, and routine measurements of the water table that, in our opinion, can be used to extend simple exchange concepts from the hyporheic exchange scale to a scale of stream-catchment connection. Copyright 2011 by the American Geophysical Union.

  2. Hierarchically designed three-dimensional macro/mesoporous carbon frameworks for advanced electrochemical capacitance storage.

    PubMed

    Yang, Yanbing; Li, Peixu; Wu, Shiting; Li, Xinyang; Shi, Enzheng; Shen, Qicang; Wu, Dehai; Xu, Wenjing; Cao, Anyuan; Yuan, Quan

    2015-04-13

    Mesoporous carbon (m-C) has potential applications as porous electrodes for electrochemical energy storage, but its applications have been severely limited by the inherent fragility and low electrical conductivity. A rational strategy is presented to construct m-C into hierarchical porous structures with high flexibility by using a carbon nanotube (CNT) sponge as a three-dimensional template, and grafting Pt nanoparticles at the m-C surface. This method involves several controllable steps including solution deposition of a mesoporous silica (m-SiO2 ) layer onto CNTs, chemical vapor deposition of acetylene, and etching of m-SiO2 , resulting in a CNT@m-C core-shell or a CNT@m-C@Pt core-shell hybrid structure after Pt adsorption. The underlying CNT network provides a robust yet flexible support and a high electrical conductivity, whereas the m-C provides large surface area, and the Pt nanoparticles improves interfacial electron and ion diffusion. Consequently, specific capacitances of 203 and 311 F g(-1) have been achieved in these CNT@m-C and CNT@m-C@Pt sponges as supercapacitor electrodes, respectively, which can retain 96 % of original capacitance under large degree compression. PMID:25752493

  3. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Summary and Guide for Stakeholders

    SciTech Connect

    Not Available

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

  4. New latent heat storage system with nanoparticles for thermal management of electric vehicles

    NASA Astrophysics Data System (ADS)

    Javani, N.; Dincer, I.; Naterer, G. F.

    2014-12-01

    In this paper, a new passive thermal management system for electric vehicles is developed. A latent heat thermal energy storage with nanoparticles is designed and optimized. A genetic algorithm method is employed to minimize the length of the heat exchanger tubes. The results show that even the optimum length of a shell and tube heat exchanger becomes too large to be employed in a vehicle. This is mainly due to the very low thermal conductivity of phase change material (PCM) which fills the shell side of the heat exchanger. A carbon nanotube (CNT) and PCM mixture is then studied where the probability of nanotubes in a series configuration is defined as a deterministic design parameter. Various heat transfer rates, ranging from 300 W to 600 W, are utilized to optimize battery cooling options in the heat exchanger. The optimization results show that smaller tube diameters minimize the heat exchanger length. Furthermore, finned tubes lead to a higher heat exchanger length due to more heat transfer resistance. By increasing the CNT concentration, the optimum length of the heat exchanger decreases and makes the improved thermal management system a more efficient and competitive with air and liquid thermal management systems.

  5. A novel multimode hybrid energy storage system and its energy management strategy for electric vehicles

    NASA Astrophysics Data System (ADS)

    Wang, Bin; Xu, Jun; Cao, Binggang; Zhou, Xuan

    2015-05-01

    This paper proposes a novel topology of multimode hybrid energy storage system (HESS) and its energy management strategy for electric vehicles (EVs). Compared to the conventional HESS, the proposed multimode HESS has more operating modes and thus it could in further enhance the efficiency of the system. The rule-based control strategy and the power-balancing strategy are developed for the energy management strategy to realize mode selection and power distribution. Generally, the DC-DC converter will operate at peak efficiency to convey the energy from the batteries to the UCs. Otherwise, the pure battery mode or the pure ultracapacitors (UCs) mode will be utilized without the DC-DC converter. To extend the battery life, the UCs have the highest priority to recycle the energy and the batteries are isolated from being recharged directly during regenerative braking. Simulations and experiments are established to validate the proposed multimode HESS and its energy management strategy. The results reveal that the energy losses in the DC-DC converter, the total energy consumption and the overall system efficiency of the proposed multimode HESS are improved compared to the conventional HESS.

  6. Hepatocellular carcinoma: Advances in diagnosis, management, and long term outcome

    PubMed Central

    Bodzin, Adam S; Busuttil, Ronald W

    2015-01-01

    Hepatocellular carcinoma (HCC) remains a common and lethal malignancy worldwide and arises in the setting of a host of diseases. The incidence continues to increase despite multiple vaccines and therapies for viruses such as the hepatitis B and C viruses. In addition, due to the growing incidence of obesity in Western society, there is anticipation that there will be a growing population with HCC due to non-alcoholic fatty liver disease. Due to the growing frequency of this disease, screening is recommended using ultrasound with further imaging using magnetic resonance imaging and multi-detector computed tomography used for further characterization of masses. Great advances have been made to help with the early diagnosis of small lesions leading to potential curative resection or transplantation. Resection and transplantation maybe used in a variety of patients that are carefully selected based on underlying liver disease. Using certain guidelines and clinical acumen patients may have good outcomes with either resection or transplantation however many patients are inoperable at time of presentation. Fortunately, the use of new locoregional therapies has made down staging patients a potential option making them potential surgical candidates. Despite a growing population with HCC, new advances in viral therapies, chemotherapeutics, and an expanding population of surgical and transplant candidates might all contribute to improved long-term survival of these patients. PMID:26019732

  7. Control and Size Energy Storage for Managing Energy balance of Variable Generation Resources

    SciTech Connect

    Ke, Xinda; Lu, Ning; Jin, Chunlian

    2015-01-01

    This paper presents control algorithms and sizing strategies for using energy storage to manage energy balance for variable generation resources. The control objective is to minimize the hourly generation imbalance between the actual and the scheduled generation of the wind farm. Three control algorithms are compared: tracking power imbalance, post-compensation, and pre-compensation. Measurement data from a wind farm located in South-central Washington State are used in the study. The results show that tracking power imbalance yields the best performance by keeping the hourly energy imbalances zero. However, the energy storage system (ESS) will be significantly oversized. Post-compensation reduces power rating of the ESS but the hourly imbalance may not be kept as zero when large and long-lasting energy imbalances occur. A linear regression forecasting algorithm is developed for the pre-compensation algorithm to pre-charge or pre-discharge the ESS based on predicted energy imbalances. The performance comparison shows that the pre-compensation method significantly reduces the size of the ESS while maintaining satisfactory performance.

  8. Ocular manifestations and management recommendations of lysosomal storage disorders I: mucopolysaccharidoses

    PubMed Central

    Fenzl, Carlton R; Teramoto, Kyla; Moshirfar, Majid

    2015-01-01

    The mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by inborn errors of glycosaminoglycan (GAG) metabolism. These diseases are classified by enzyme deficiency into seven groups: type I, II, III, IV, VI, VII, and IX. GAG accumulation leads to characteristic clinical features. Some ophthalmic findings that are characteristic of MPS diseases include corneal clouding, retinal degeneration, decreased electroretinogram wave amplitude, optic atrophy, papilledema, and glaucoma. Current treatments such as hematopoietic stem cell transplantation and enzyme replacement therapy have increased the life span of many MPS patients and created the need to improve management of ocular symptoms. This article aims to provide a comprehensive review of ocular manifestations and treatment options for the various types of MPS. PMID:26379420

  9. Ocular manifestations and management recommendations of lysosomal storage disorders I: mucopolysaccharidoses.

    PubMed

    Fenzl, Carlton R; Teramoto, Kyla; Moshirfar, Majid

    2015-01-01

    The mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by inborn errors of glycosaminoglycan (GAG) metabolism. These diseases are classified by enzyme deficiency into seven groups: type I, II, III, IV, VI, VII, and IX. GAG accumulation leads to characteristic clinical features. Some ophthalmic findings that are characteristic of MPS diseases include corneal clouding, retinal degeneration, decreased electroretinogram wave amplitude, optic atrophy, papilledema, and glaucoma. Current treatments such as hematopoietic stem cell transplantation and enzyme replacement therapy have increased the life span of many MPS patients and created the need to improve management of ocular symptoms. This article aims to provide a comprehensive review of ocular manifestations and treatment options for the various types of MPS. PMID:26379420

  10. Active Management of Integrated Geothermal-CO2 Storage Reservoirs in Sedimentary Formations

    DOE Data Explorer

    Buscheck, Thomas A.

    2012-01-01

    The purpose of phase 1 is to determine the feasibility of integrating geologic CO2 storage (GCS) with geothermal energy production. Phase 1 includes reservoir analyses to determine injector/producer well schemes that balance the generation of economically useful flow rates at the producers with the need to manage reservoir overpressure to reduce the risks associated with overpressure, such as induced seismicity and CO2 leakage to overlying aquifers. This submittal contains input and output files of the reservoir model analyses. A reservoir-model "index-html" file was sent in a previous submittal to organize the reservoir-model input and output files according to sections of the FY1 Final Report to which they pertain. The recipient should save the file: Reservoir-models-inputs-outputs-index.html in the same directory that the files: Section2.1.*.tar.gz files are saved in.

  11. Workload-Adaptive Management of Energy-Smart Disk Storage Systems

    SciTech Connect

    Otoo, Ekow; Rotem, Doron; Tsao, Shih-Chiang

    2009-06-19

    Recent studies have identified disk storage systems as one of the major consumers of power in data centers. Many disk power management (DPM) schemes were suggested where the power consumed by disks is reduced by spinning them down during long idle periods. Spinning the disks down and up results in additional energy and response time costs. For that reason, DPM schemes are effective only if the disks experience relatively long idle periods and the scheme does not introduce a severe response time penalty. In this paper we introduce a dynamic block exchange algorithm which switches data between disks based on the observed workload such that frequently accessed blocks end up residing on a few"hot" disks thus allowing the majority of disks to experience longer idle periods. We validate the effectiveness of the algorithm with trace-driven simulations showing power savings of up to 60percent with very small response time penalties.

  12. A Profile and Management of the US Army's underground storage tanks

    NASA Astrophysics Data System (ADS)

    Dharmavaram, Seshasayi; Piskin, Kemal; Hoctor, Theresa J.; Donahue, Bernard A.

    1989-05-01

    The US Army owns more than 10,000 underground storage tanks (USTs), many of which are old and may be leaking. The Resource Conservation and Recovery Act of 1976 required tank owners to collect and report data on them by May 1986. In order to manage the large amounts of information on its USTs, the Army developed a microcomputer-based data base system. The data base system is user friendly and allows the user to store, organize, and manipulate the UST data. A leak potential index (LPI) was also developed and calculated for each of the Army's USTs. The LPI is used to prioritize USTs so that those with higher LPIs can be monitored closely. A characteristic profile of Army USTs according to construction material, capacity, age, content, and LPI is presented in this paper.

  13. Foundational Report Series: Advanced Distribution Management Systems for Grid Modernization

    SciTech Connect

    Wang, Jianhui

    2015-09-01

    This report describes the application functions for distribution management systems (DMS). The application functions are those surveyed by the IEEE Power and Energy Society’s Task Force on Distribution Management Systems. The description of each DMS application includes functional requirements and the key features and characteristics in current and future deployments, as well as a summary of the major benefits provided by each function to stakeholders — from customers to shareholders. Due consideration is paid to the fact that the realizable benefits of each function may differ by type of utility, whether investor-owned, cooperative, or municipal. This report is sufficient to define the functional requirements of each application for system procurement (request-for-proposal [RFP]) purposes and for developing preliminary high-level use cases for those functions. However, it should not be considered a design document that will enable a vendor or software developer to design and build actual DMS applications.

  14. Duodenal adenocarcinoma: Advances in diagnosis and surgical management

    PubMed Central

    Cloyd, Jordan M; George, Elizabeth; Visser, Brendan C

    2016-01-01

    Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma (DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticoduodenectomy or segmental duodenal resection; either are acceptable options as long as negative margins are achievable and an adequate lymphadenectomy can be performed. Adjuvant chemotherapy and radiation are important components of multi-modality treatment for patients at high risk of recurrence. Further research would benefit from multi-institutional trials that do not combine DA with other periampullary or small bowel malignancies. The purpose of this article is to perform a comprehensive review of DA with special focus on the surgical management and principles. PMID:27022448

  15. Results of an Advanced Development Zero Boil-Off Cryogenic Propellant Storage Test

    NASA Technical Reports Server (NTRS)

    Plachta, David

    2004-01-01

    A zero boil-off (ZBO) cryogenic propellant storage concept was recently tested in a thermally relevant low-earth orbit environment, an important development in the effort to apply this concept to flight projects. Previous efforts documented the benefits of ZBO for launch vehicle upper stages in a low-earth orbit (LEO). Central to that analysis is a ZBO Cryogenic Analysis Tool that estimates the performance of each component and the ZBO system. This test is essential to the validation of that tool, and was the first flight representative configuration tested in a thermally representative environment. The test article was comprised of a spherical 1.4 m diameter insulated propellant tank, with a submerged mixer, a cryogenic heat pipe, flight design cryocooler, and a radiator. All were enclosed in a thermal shroud and inserted into and tested in a vacuum chamber that simulated an LEO thermal environment. Thermal and pressure control tests were performed at sub-critical LN2 temperatures and approximately 2 atmospheres pressure. The cold side of the ZBO system performed well. In particular, the heat pipe performed better than expected, which suggests that the cryocooler could be located further from the tank than anticipated, i.e. on a spacecraft bus, while maintaining the desired efficiency. Also, the mixer added less heat than expected. The tank heating rate through the insulation was higher than expected; also the temperatures on the cryocooler hot side were higher than planned. This precluded the cryocooler from eliminating the boil-off. The results show the cryocooler was successful at removing 6.8 W of heat at approximately 75 K and 150 W of input power, with a heat rejection temperature of 311 K. The data generated on the ZBO components is essential for the upgrade of the ZBO Cryogenic Analysis Tool to more accurately apply the concept to future missions.

  16. Recent advances in managing and understanding diabetic nephropathy

    PubMed Central

    Tang, Sydney C.W.; Chan, Gary C.W.; Lai, Kar Neng

    2016-01-01

    Diabetic nephropathy is the commonest cause of end-stage renal disease in most developed economies. Current standard of care for diabetic nephropathy embraces stringent blood pressure control via blockade of the renin-angiotensin-aldosterone system and glycemia control. Recent understanding of the pathophysiology of diabetic nephropathy has led to the development of novel therapeutic options. This review article focuses on available data from landmark studies on the main therapeutic approaches and highlights some novel management strategies. PMID:27303648

  17. Recommendations for managing cutaneous disorders associated with advancing age

    PubMed Central

    Humbert, Philippe; Dréno, Brigitte; Krutmann, Jean; Luger, Thomas Anton; Triller, Raoul; Meaume, Sylvie; Seité, Sophie

    2016-01-01

    The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermatological problems associated with the loss of cutaneous function with age. As cell renewal slows, the physical and chemical barrier function declines, cutaneous permeability increases, and the skin becomes increasingly vulnerable to external factors. In geriatric dermatology, the consequences of cutaneous aging lead to xerosis, skin folding, moisture-associated skin damage, and impaired wound healing. These problems pose significant challenges for both the elderly and their carers. Most often, nurses manage skin care in the elderly. However, until recently, little attention has been paid to developing appropriate, evidence-based, skincare protocols. The objective of this paper is to highlight common clinical problems with aging skin and provide some appropriate advice on cosmetic protocols for managing them. A review of the literature from 2004 to 2014 using PubMed was performed by a working group of six European dermatologists with clinical and research experience in dermatology. Basic topical therapy can restore and protect skin barrier function, which relieves problems associated with xerosis, prevents aggravating moisture-associated skin damage, and enhances quality of life. In conclusion, the authors provide physicians with practical recommendations to assist them in implementing basic skin care for the elderly in an integrated care approach. PMID:26929610

  18. Recommendations for managing cutaneous disorders associated with advancing age.

    PubMed

    Humbert, Philippe; Dréno, Brigitte; Krutmann, Jean; Luger, Thomas Anton; Triller, Raoul; Meaume, Sylvie; Seité, Sophie

    2016-01-01

    The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermatological problems associated with the loss of cutaneous function with age. As cell renewal slows, the physical and chemical barrier function declines, cutaneous permeability increases, and the skin becomes increasingly vulnerable to external factors. In geriatric dermatology, the consequences of cutaneous aging lead to xerosis, skin folding, moisture-associated skin damage, and impaired wound healing. These problems pose significant challenges for both the elderly and their carers. Most often, nurses manage skin care in the elderly. However, until recently, little attention has been paid to developing appropriate, evidence-based, skincare protocols. The objective of this paper is to highlight common clinical problems with aging skin and provide some appropriate advice on cosmetic protocols for managing them. A review of the literature from 2004 to 2014 using PubMed was performed by a working group of six European dermatologists with clinical and research experience in dermatology. Basic topical therapy can restore and protect skin barrier function, which relieves problems associated with xerosis, prevents aggravating moisture-associated skin damage, and enhances quality of life. In conclusion, the authors provide physicians with practical recommendations to assist them in implementing basic skin care for the elderly in an integrated care approach. PMID:26929610

  19. Specific transport and storage solutions : waste management facing current and future stakes of the nuclear fuel cycle

    SciTech Connect

    Choho, T.; Blachet, L.; Deniau, H.; Gagner, L.; Gendreau, F.; Presta, A.

    2007-07-01

    With major projects ongoing or being planned, and also with the daily management of radioactive waste from nuclear facilities, the role of transport and/or storage packaging has been often overlooked. Indeed, the packaging development process and transport solutions implemented are a key part of the waste management challenge : protection of people and of the environment. During over four decades, the AREVA Group has developed a complete and coherent system for the transport of waste produced by nuclear industries. The transport solutions integrate the factors to consider, as industrial transportation needs, various waste forms, associated hazards and current regulations. Thus, TN International has designed, licensed and manufactured a large number of different transport, storage and dual purpose cask models for residues and all kinds of radioactive wastes. The present paper proposes to illustrate how a company acting both as a cask designer and a carrier is key to the waste management issue and how it can support the waste management policy of nuclear waste producers through their operational choices. We will focus on the TN International technical solutions implemented to guarantee safe and secure transportation and storage solutions. We will describe different aspects of the cask design process, insisting on how it enables to fulfil both customer needs and regulation requirements. We will also mention the associated services developed by the AREVA Business Unit Logistics (TN International, TRANSNUCLEAR, MAINCO, and LMC) in order to manage transportation of liquid and solid waste towards interim or final storage sites. (authors)

  20. Managing aging effects on dry cask storage systems for extended long-term storage and transportation of used fuel - rev. 0

    SciTech Connect

    Chopra, O.K.; Diercks, D.; Fabian, R.; Ma, D.; Shah, V.; Tam, S.W.; Liu, Y.

    2012-07-06

    The cancellation of the Yucca Mountain repository program in the United States raises the prospect of extended long-term storage (i.e., >120 years) and deferred transportation of used fuel at operating and decommissioned nuclear power plant sites. Under U.S. federal regulations contained in Title 10 of the Code of Federal Regulations (CFR) 72.42, the initial license term for an Independent Spent Fuel Storage Installation (ISFSI) must not exceed 40 years from the date of issuance. Licenses may be renewed by the U.S. Nuclear Regulatory Commission (NRC) at the expiration of the license term upon application by the licensee for a period not to exceed 40 years. Application for ISFSI license renewals must include the following: (1) Time-limited aging analyses (TLAAs) that demonstrate that structures, systems, and components (SSCs) important to safety will continue to perform their intended function for the requested period of extended operation; and (2) a description of the aging management program (AMP) for management of issues associated with aging that could adversely affect SSCs important to safety. In addition, the application must also include design bases information as documented in the most recent updated final safety analysis report as required by 10 CFR 72.70. Information contained in previous applications, statements, or reports filed with the Commission under the license may be incorporated by reference provided that those references are clear and specific. The NRC has recently issued the Standard Review Plan (SRP) for renewal of used-fuel dry cask storage system (DCSS) licenses and Certificates of Compliance (CoCs), NUREG-1927, under which NRC may renew a specific license or a CoC for a term not to exceed 40 years. Both the license and the CoC renewal applications must contain revised technical requirements and operating conditions (fuel storage, surveillance and maintenance, and other requirements) for the ISFSI and DCSS that address aging effects that

  1. Recent advances in managing human papillomavirus-positive oropharyngeal tumors

    PubMed Central

    Riccio, Stefano; Colombo, Sarah; Pompilio, Madia; Formillo, Paolo

    2010-01-01

    Human papillomavirus (HPV) is detected in a subset of patients with head and neck squamous cell carcinoma, most frequently in tumors in the Waldeyer's ring (palatine tonsil and base of tongue). Several studies suggest that patients with HPV-positive tumors have better survival with either concurrent chemoradiation therapy or surgery followed by radiation compared with HPV-negative patients. However, some possible confounding clinicopathologic variables may challenge the validity of this statement, for example, some authors used the TNM (tumor, node, metastasis) grouping stage while others used the primary tumor (T stage), and other studies have demonstrated that tumors with advanced T stage were less likely to be infected with HPV. A large clinical trial with stratification of patients according to all known tumor prognostic factors is crucial to solve the question. PMID:20948869

  2. Emerging Advances in the Management of Cardiac Amyloidosis.

    PubMed

    Vranian, Michael N; Sperry, Brett W; Valent, Jason; Hanna, Mazen

    2015-11-01

    Amyloidosis is a disease in which proteins misfold, aggregate into fibrils, and deposit extracellularly disrupting organ architecture and function. There are two main types which affect the heart: light chain (AL) amyloidosis and transthyretin cardiac amyloidosis (ATTR). There is a misconception that cardiac amyloidosis has no effective treatment options. However, over the past decade, there has been extensive research and drug development. Outcomes are improving in AL amyloidosis with evolving chemotherapeutic regimens and novel monoclonal antibodies. In ATTR, therapies that decrease protein production, prevent dissociation, and promote clearance have the potential to slow or even halt a disease which is uniformly fatal. Selected patients may be candidates for heart and/or stem cell transplant and should be promptly referred to an experienced amyloid program. Herein, we discuss the emerging advances for the treatment of cardiac amyloidosis. PMID:26374453

  3. Maxillomandibular Advancement in the Management of Obstructive Sleep Apnea

    PubMed Central

    Varghese, Ranji; Adams, Nathan G.; Slocumb, Nancy L.; Viozzi, Christopher F.; Ramar, Kannan; Olson, Eric J.

    2012-01-01

    Maxillomandibular advancement (MMA) is a surgical option for obstructive sleep apnea (OSA). MMA involves forward-fixing the maxilla and mandible approximately 10  mm via Le Fort I maxillary and sagittal split mandibular osteotomies. We retrospectively reviewed outcomes from 24 consecutive OSA patients who underwent MMA at our institution. MMA resulted in an 83% reduction in the group mean apnea-hypopnea index (AHI) per polysomnography an average of 6.7 months after surgery. Forty-two percent of patients achieved a post-MMA AHI of less than 5 events/hour sleep and 71% achieved an AHI less than or equal to 10 events/hour sleep. The Epworth Sleepiness Scale score decreased by an average of 5 post-surgery. No parameters predictive of cure for OSA by MMA were identified. PMID:22518154

  4. Advances in nanotechnology for the management of coronary artery disease.

    PubMed

    Rhee, June-Wha; Wu, Joseph C

    2013-02-01

    Nanotechnology holds tremendous potential to advance the current treatment of coronary artery disease. Nanotechnology may assist medical therapies by providing a safe and efficacious delivery platform for a variety of drugs aimed at modulating lipid disorders, decreasing inflammation and angiogenesis within atherosclerotic plaques, and preventing plaque thrombosis. Nanotechnology may improve coronary stent applications by promoting endothelial recovery on a stent surface utilizing bio-mimetic nanofibrous scaffolds, and also by preventing in-stent restenosis using nanoparticle-based delivery of drugs that are decoupled from stents. Additionally, nanotechnology may enhance tissue-engineered graft materials for application in coronary artery bypass grafting by facilitating cellular infiltration and remodeling of a graft matrix. PMID:23245913

  5. Advanced techniques and technology for efficient data storage, access, and transfer

    NASA Technical Reports Server (NTRS)

    Rice, Robert F.; Miller, Warner

    1991-01-01

    Advanced techniques for efficiently representing most forms of data are being implemented in practical hardware and software form through the joint efforts of three NASA centers. These techniques adapt to local statistical variations to continually provide near optimum code efficiency when representing data without error. Demonstrated in several earlier space applications, these techniques are the basis of initial NASA data compression standards specifications. Since the techniques clearly apply to most NASA science data, NASA invested in the development of both hardware and software implementations for general use. This investment includes high-speed single-chip very large scale integration (VLSI) coding and decoding modules as well as machine-transferrable software routines. The hardware chips were tested in the laboratory at data rates as high as 700 Mbits/s. A coding module's definition includes a predictive preprocessing stage and a powerful adaptive coding stage. The function of the preprocessor is to optimally process incoming data into a standard form data source that the second stage can handle.The built-in preprocessor of the VLSI coder chips is ideal for high-speed sampled data applications such as imaging and high-quality audio, but additionally, the second stage adaptive coder can be used separately with any source that can be externally preprocessed into the 'standard form'. This generic functionality assures that the applicability of these techniques and their recent high-speed implementations should be equally broad outside of NASA.

  6. Design Considerations for Financing a National Trust to Advance the Deployment of Geologic CO2 Storage and Motivate Best Practices

    SciTech Connect

    Dooley, James J.; Trabucchi, Chiara; Patton , Lindene

    2010-03-01

    This paper explores how the flawed, widely held public policy view of an ever growing risk associated with long-term carbon dioxide (CO2) storage profoundly influences the public policy dialogue about how to best address the long term risk profile for geologic storage. In order to accomplish this, the authors present evidence from the rapidly emerging science and engineering of CO2 storage which demonstrates that, with proper site characterization and sound operating practices, retention of stored CO2 will increase with time thus invalidating the premise of an ever growing risk. The authors focus on key issues of fit, interplay, and scalability associated with a trust fund funded by a hypothetical $1/tonCO2 tipping fee for each ton of CO2 stored in the United States under WRE450 and WRE550 climate policies. The authors conclude there is no intrinsic value in creating a trust fund predicated solely on collecting a fixed fee that is not mapped to site-specific risk profiles. If left to grow unchecked, a trust fund that is predicated on a constant stream of annual payments unrelated to the site’s risk profile could result in the accumulation of hundreds of billions to more than a trillion dollars in real terms contributing to significant opportunity cost of capital. Further, rather than mitigating the financial consequences of long-term CCS risks, this analysis suggests a blanket $1/tonCO2 tipping fee may increase the probability and frequency of long-term risk by eliminating financial incentives for sound operating behavior and site selection criteria – contribute to moral hazard. At a minimum, effective use of a trust fund requires: (1) strong oversight regarding site selection and fund management, and (2) a clear process by which the fund is periodically valued and funds collected are mapped to the risk profile of the pool of covered CCS sites. Without appropriate checks and balances, there is no a priori reason to believe that the amount of funds held in trust

  7. Does Multidisciplinary Care Enhance the Management of Advanced Breast Cancer?: Evaluation of Advanced Breast Cancer Multidisciplinary Team Meetings

    PubMed Central

    Chirgwin, Jacquie; Craike, Melinda; Gray, Christine; Watty, Kathy; Mileshkin, Linda; Livingston, Patricia M.

    2010-01-01

    Purpose: To assess the contribution of the advanced breast cancer (ABC) multidisciplinary team meetings (MDMs) to patient care and clinical outcomes. Methods: Members of ABC MDMs at two health services completed questionnaires in November 2007. The questionnaire asked about the performance of the MDMs and their contribution to improvement in patient care in five domains: medical management, psychosocial care, palliative care, care in the community, and benefits for team members. A final section covered the perceived value and importance of the MDM in patient management. Descriptive statistics (frequencies, mean, and standard deviation) were used to summarize the performance, improvement, and importance scores. Results: A total of 27 multidisciplinary team members (73%) completed the questionnaire. The MDM performed best in medical management (mean performance score out of 5 [M] = 3.78) and palliative care (M = 3.77). These were also the areas that were most improved through the MDM. Benefits to team members and care in the community (both M = 3.05) ranked lowest by both measures. The MDM provided the most benefit for patient management in the areas of “awareness of services available” (M = 4.32), “efficiency of referrals” (M = 4.27) and “supportive care for patients” (M = 4.27). “Awareness of services available,” “psychological care for patients,” and “continuity of care” were considered the most important (M = 4.64). Conclusion: The study provides evidence that MDMs make an important contribution to the logistical and medical management of patients with advanced breast cancer. PMID:21358959

  8. Advanced high-speed flywheel energy storage systems for pulsed power application

    NASA Astrophysics Data System (ADS)

    Talebi Rafsanjan, Salman

    Power systems on modern commercial transportation systems are moving to more electric based equipment, thus improving the reliability of the overall system. Electrical equipment on such systems will include some loads that require very high power for short periods of time, on the order of a few seconds, especially during acceleration and deceleration. The current approach to solving this problem is sizing the electrical grid for peak power, rather than the average. A method to efficiently store and discharge the pulsed power is necessary to eliminate the cost and weight of oversized generation equipment to support the pulsed power needs of these applications. Highspeed Flywheel Energy Storage Systems (FESS) are effectively capable of filling the niche of short duration, high cycle life applications where batteries and ultra capacitors are not usable. In order to have an efficient high-speed FESS, performing three important steps towards the design of the overall system are extremely vital. These steps are modeling, analysis and control of the FESS that are thoroughly investigated in this dissertation. This dissertation establishes a comprehensive analysis of a high-speed FESS in steady state and transient operations. To do so, an accurate model for the complete FESS is derived. State space averaging approach is used to develop DC and small-signal AC models of the system. These models effectively simplify analysis of the FESS and give a strong physical intuition to the complete system. In addition, they result in saving time and money by avoiding time consuming simulations performed by expensive packages, such as Simulink, PSIM, etc. In the next step, two important factors affecting operation of the Permanent Magnet Synchronous Machine (PMSM) implemented in the high-speed FESS are investigated in detail and outline a proper control strategy to achieve the required performance by the system. Next, a novel design algorithm developed by S.P. Bhattacharyya is used to

  9. Revolutionary advances in medical waste management. The Sanitec system.

    PubMed

    Edlich, Richard F; Borel, Lise; Jensen, H Gordon; Winters, Kathryne L; Long, William B; Gubler, K Dean; Buschbacher, Ralph M; Becker, Daniel G; Chang, Dillon E; Korngold, Jonathan; Chitwood, W Randolph; Lin, Kant Y; Nichter, Larry S; Berenson, Susan; Britt, L D; Tafel, John A

    2006-01-01

    It is the purpose of this collective review to provide a detailed outline of a revolutionary medical waste disposal system that should be used in all medical centers in the world to prevent pollution of our planet from medical waste. The Sanitec medical waste disposal system consists of the following seven components: (1) an all-weather steel enclosure of the waste management system, allowing it to be used inside or outside of the hospital center; (2) an automatic mechanical lift-and-load system that protects the workers from devastating back injuries; (3) a sophisticated shredding system designed for medical waste; (4) a series of air filters including the High Efficiency Particulate Air (HEPA) filter; (5) microwave disinfection of the medical waste material; (6) a waste compactor or dumpster; and (7) an onboard microprocessor. It must be emphasized that this waste management system can be used either inside or outside the hospital. From start to finish, the Sanitec Microwave Disinfection system is designed to provide process and engineering controls that assure complete disinfection and destruction, while minimizing the operator's exposure to risk. There are numerous technologic benefits to the Sanitec systems, including environmental, operational, physical, and disinfection efficiency as well as waste residue disinfection. Wastes treated through the Sanitec system are thoroughly disinfected, unrecognizable, and reduced in volume by approximately 80% (saving valuable landfill space and reducing hauling requirements and costs). They are acceptable in any municipal solid waste program. Sanitec's Zero Pollution Advantage is augmented by a complete range of services, including installation, startup, testing, training, maintenance, and repair, over the life of this system. The Sanitec waste management system has essentially been designed to provide the best overall solution to the customer, when that customer actually looks at the total cost of dealing with the

  10. Principled negotiation and distributed optimization for advanced air traffic management

    NASA Astrophysics Data System (ADS)

    Wangermann, John Paul

    Today's aircraft/airspace system faces complex challenges. Congestion and delays are widespread as air traffic continues to grow. Airlines want to better optimize their operations, and general aviation wants easier access to the system. Additionally, the accident rate must decline just to keep the number of accidents each year constant. New technology provides an opportunity to rethink the air traffic management process. Faster computers, new sensors, and high-bandwidth communications can be used to create new operating models. The choice is no longer between "inflexible" strategic separation assurance and "flexible" tactical conflict resolution. With suitable operating procedures, it is possible to have strategic, four-dimensional separation assurance that is flexible and allows system users maximum freedom to optimize operations. This thesis describes an operating model based on principled negotiation between agents. Many multi-agent systems have agents that have different, competing interests but have a shared interest in coordinating their actions. Principled negotiation is a method of finding agreement between agents with different interests. By focusing on fundamental interests and searching for options for mutual gain, agents with different interests reach agreements that provide benefits for both sides. Using principled negotiation, distributed optimization by each agent can be coordinated leading to iterative optimization of the system. Principled negotiation is well-suited to aircraft/airspace systems. It allows aircraft and operators to propose changes to air traffic control. Air traffic managers check the proposal maintains required aircraft separation. If it does, the proposal is either accepted or passed to agents whose trajectories change as part of the proposal for approval. Aircraft and operators can use all the data at hand to develop proposals that optimize their operations, while traffic managers can focus on their primary duty of ensuring

  11. Advances in chest drain management in thoracic disease

    PubMed Central

    George, Robert S.

    2016-01-01

    An adequate chest drainage system aims to drain fluid and air and restore the negative pleural pressure facilitating lung expansion. In thoracic surgery the post-operative use of the conventional underwater seal chest drainage system fulfills these requirements, however they allow great variability amongst practices. In addition they do not offer accurate data and they are often inconvenient to both patients and hospital staff. This article aims to simplify the myths surrounding the management of chest drains following chest surgery, review current experience and explore the advantages of modern digital chest drain systems and address their disease-specific use. PMID:26941971

  12. Recent advances in the recognition and management of eosinophilic esophagitis

    PubMed Central

    Eustace, Gregory; Gui, Xianyong; Iacucci, Marietta

    2015-01-01

    The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both histological and endoscopic criteria have been developed and validated. Dietary therapy, topical steroid therapy, proton pump inhibitors and endoscopic dilation are the main approaches to therapy; however, novel targeted therapies are being developed. Among the food items commonly implicated are wheat, dairy, nuts, soy, shellfish and eggs. A multidisciplinary approach to management in dedicated clinics may yield the best results. PMID:26076223

  13. Advances in Research on Contingency Management for Adolescent Substance Use.

    PubMed

    Stanger, Catherine; Lansing, Amy Hughes; Budney, Alan J

    2016-10-01

    Multiple interventions for treating adolescents with substance use disorders have demonstrated efficacy, but a majority of teens do not show an enduring positive response to these treatments. Contingency management (CM)-based strategies provide a promising alternative, and clinical research focused on the development and testing of innovative CM models continues to grow. This article provides an updated review on the progress made in this area. It is important to continue to search for more effective models, focus on post-treatment maintenance (reduce relapse), and strive for high levels of integrity and fidelity during dissemination efforts to optimize outcomes. PMID:27613343

  14. Recent advances in omic technologies for meat quality management.

    PubMed

    Picard, B; Lebret, B; Cassar-Malek, I; Liaubet, L; Berri, C; Le Bihan-Duval, E; Hocquette, J F; Renand, G

    2015-11-01

    The knowledge of the molecular organization of living organisms evolved considerably during the last years. The methodologies associated also progressed with the development of the high-throughput sequencing (SNP array, RNAseq, etc.) and of genomic tools allowing the simultaneous analysis of hundreds or thousands of genes, proteins or metabolites. In farm animals, some proteins, mRNAs or metabolites whose abundance has been associated with meat quality traits have been detected in pig, cattle, chicken. They constitute biomarkers for the assessment and prediction of qualities of interest in each species, with potential biomarkers across species. The ongoing development of rapid methods will allow their use for decision-making and management tools in slaughterhouses, to better allocate carcasses or cuts to the appropriate markets. Besides, their application on living animals will help to improve genetic selection and to adapt a breeding system to fulfill expected quality level. The ultimate goal is to propose effective molecular tools for the management of product quality in meat production chains. PMID:26002117

  15. Advanced Scientific Computing Environment Team new scientific database management task

    SciTech Connect

    Church, J.P.; Roberts, J.C.; Sims, R.N.; Smetana, A.O.; Westmoreland, B.W.

    1991-06-01

    The mission of the ASCENT Team is to continually keep pace with, evaluate, and select emerging computing technologies to define and implement prototypic scientific environments that maximize the ability of scientists and engineers to manage scientific data. These environments are to be implemented in a manner consistent with the site computing architecture and standards and NRTSC/SCS strategic plans for scientific computing. The major trends in computing hardware and software technology clearly indicate that the future computer'' will be a network environment that comprises supercomputers, graphics boxes, mainframes, clusters, workstations, terminals, and microcomputers. This network computer'' will have an architecturally transparent operating system allowing the applications code to run on any box supplying the required computing resources. The environment will include a distributed database and database managing system(s) that permits use of relational, hierarchical, object oriented, GIS, et al, databases. To reach this goal requires a stepwise progression from the present assemblage of monolithic applications codes running on disparate hardware platforms and operating systems. The first steps include converting from the existing JOSHUA system to a new J80 system that complies with modern language standards, development of a new J90 prototype to provide JOSHUA capabilities on Unix platforms, development of portable graphics tools to greatly facilitate preparation of input and interpretation of output; and extension of Jvv'' concepts and capabilities to distributed and/or parallel computing environments.

  16. Recent advances in the US Department of Energy's energy storage technology research and development programs for hybrid electric and electric vehicles

    NASA Astrophysics Data System (ADS)

    Weinstock, Irwin B.

    This paper provides an overview of recent advances in battery technology resulting from the Department of Energy's (DOE's) energy storage research and development (R&D) programs for hybrid electric vehicles (HEVs) and electrical vehicles (EVs). The DOE's Office of Advanced Automotive Technologies (OAAT) is working with industry, national laboratories, universities, and other government agencies to develop technologies that will lead to a reduction in the petroleum used and the emissions generated by the transportation sector. The programs reviewed in this paper are focused on accelerating the development of energy storage technologies that are critical for the commercialization of HEVs and EV. These include the research conducted at DOE's national laboratories to develop the high-power batteries needed for hybrid electric vehicles (HEVs) and the collaborative research with the US Advanced Battery Consortium (USABC) to develop the high-energy batteries needed for EVs.

  17. Recent advances towards a theory of catchment hydrologic transport: age-ranked storage and the Ω-functions

    NASA Astrophysics Data System (ADS)

    Harman, C. J.

    2014-12-01

    Models that faithfully represent spatially-integrated hydrologic transport through the critical zone at sub-watershed scales are essential building blocks for large-scale models of land use and climate controls on non-point source contaminant delivery. A particular challenge facing these models is the need to represent the delay between inputs of soluble contaminants (such as nitrate) at the field scale, and the solute load that appears in streams. Recent advances in the theory of time-variable transit time distributions (e.g. Botter et al., GRL 38(L11403), 2011) have provided a rigorous framework for representing conservative solute transport and its coupling to hydrologic variability and partitioning. Here I will present a reformulation of this framework that offers several distinct advantages over existing formulations: 1) the derivation of the governing conservation equation is simple and intuitive, 2) the closure relations are expressed in a convenient and physically meaningful way as probability distributions Ω(ST)Omega(S_T) over the storage ranked by age STS_T, and 3) changes in transport behavior determined by storage-dependent dilution and flow-path dynamics (as distinct from those due only to changes in the rates and partitioning of water flux) are completely encapsulated by these probability distributions. The framework has been implemented to model to the rich dataset of long-term stream and precipitation chloride from the Plynlimon watershed in Wales, UK. With suitable choices for the functional form of the closure relationships, only a small number of free parameters are required to reproduce the observed chloride dynamics as well as previous models with many more parameters, including reproducing the observed fractal 1/f filtering of the streamflow chloride variability. The modeled transport dynamics are sensitive to the input precipitation variability and water balance partitioning to evapotranspiration. Apparent storage-dependent age

  18. Trends in Energy Management Technology - Part 4: Review ofAdvanced Applications in Energy Management, Control, and InformationSystems

    SciTech Connect

    Yee, Gaymond; Webster, Tom

    2003-08-01

    In this article, the fourth in a series, we provide a review of advanced applications in Energy Management, Control, and Information Systems (EMCIS). The available features for these products are summarized and analyzed with regard to emerging trends in EMCIS and potential benefits to the Federal sector. The first article [1] covered enabling technologies for emerging energy management systems. The second article [2] serves as a basic reference for building control system (BCS) networking fundamentals and includes an assessment of current approaches to open communications. The third article [3] evaluated several products that exemplify the current state of practice in EMCIS. It is important for energy managers in the Federal sector to have a high level of knowledge and understanding of these complex energy management systems. This series of articles provides energy practitioners with some basic informational and educational tools to help make decisions relative to energy management systems design, specification, procurement, and energy savings potential.

  19. Pazopanib in the management of advanced soft tissue sarcomas

    PubMed Central

    Cranmer, Lee D; Loggers, Elizabeth T; Pollack, Seth M

    2016-01-01

    Therapy of soft tissue sarcomas represents an area of significant unmet need in oncology. Angiogenesis has been explored as a potential target both preclinically and clinically, with suggestions of activity. Pazopanib is a multitargeted tyrosine kinase inhibitor with prominent antiangiogenic effects. In a Phase II study, pazopanib demonstrated activity in strata enrolling patients with leiomyosarcomas, synovial sarcomas, or other sarcomas but not those enrolling adipocytic sarcomas. PALETTE, the pivotal Phase III trial, demonstrated improved progression-free survival versus placebo in pazopanib-treated patients previously treated for advanced soft tissue sarcomas. No survival benefit was observed, and adipocytic sarcomas were excluded. Health-related quality-of-life assessments indicated significant decrements in several areas affected by pazopanib toxicities, but no global deterioration. Cost-effectiveness analyses indicate that pazopanib therapy may or may not be cost-effective in different geographic settings. Pazopanib provides important proof-of-concept for antiangiogenic therapy in soft tissue sarcomas. Its use can be improved by further biological studies of its activity profile in sarcomas, studies of biological rational combinations, and clinicopathologic/biological correlative studies of activity to allow better drug targeting. PMID:27354810

  20. Recent advances in the management of sexual precocity in girls.

    PubMed

    Schriock, E A; Martin, M C

    1991-12-01

    Sexual precocity has important psychosocial implications for the prematurely developing child, as well as being associated in some cases with significant pathology. Conscientious evaluation and initiation of effective therapy can have a significant impact on improving long-term outcome. The differentiation between complete sexual precocity with activation of the hypothalamic-pituitary axis and incomplete sexual precocity without activation of the central reproductive system is of paramount importance. In incomplete sexual precocity, the sex steroids are of exogenous, adrenal, or gonadal origin. Premature adrenarche presents with the early development of pubic hair only and must be distinguished from adrenal hyperplasia or an androgen-secreting neoplasm, which may be associated with accelerated growth, advanced bone age, and virilization. When incomplete sexual precocity involves the ovary, ovarian tumors must be considered. Other causes of incomplete sexual precocity include hypothyroidism and gonadotropin-independent precocity such as McCune-Albright syndrome. Complete sexual precocity or precocious puberty of central origin is diagnosed in girls by gonadotropin-releasing hormone challenge yielding a stimulated luteinizing hormone peak greater than 15 IU/L. Radiologic evaluation of the central axis is necessary. Treatment of precocious puberty relies on the use of potent agonists of gonadotropin-releasing hormone that reversibly suppress the prematurely activated pituitary. Depot preparations are efficacious. Early initiation and careful monitoring of treatment can reduce physical signs of development, improve the likelihood for normal adult height, and postpone normal pubertal progression to a more appropriate age. PMID:1818719

  1. Advances in management of type 1 diabetes mellitus

    PubMed Central

    Aathira, Ravindranath; Jain, Vandana

    2014-01-01

    Treatment of type 1 diabetes mellitus has always posed a challenge to balance hyperglycemia control with hypoglycemia episodes. The quest for newer therapies is continuing and this review attempts to outline the recent developments. The insulin molecule itself has got moulded into different analogues by minor changes in its structure to ensure well controlled delivery, stable half-lives and lesser side effects. Insulin delivery systems have also consistently undergone advances from subcutaneous injections to continuous infusion to trials of inhalational delivery. Continuous glucose monitoring systems are also becoming more accurate and user friendly. Smartphones have also made their entry into therapy of diabetes by integrating blood glucose levels and food intake with calculated adequate insulin required. Artificial pancreas has enabled to a certain extent to close the loop between blood glucose level and insulin delivery with devices armed with meal and exercise announcements, dual hormone delivery and pramlintide infusion. Islet, pancreas-kidney and stem cells transplants are also being attempted though complete success is still a far way off. Incorporating insulin gene and secretary apparatus is another ambitious leap to achieve insulin independence though the search for the ideal vector and target cell is still continuing. Finally to stand up to the statement, prevention is better than cure, immunological methods are being investigated to be used as vaccine to prevent the onset of diabetes mellitus. PMID:25317246

  2. Advanced man-machine interface systems and advanced information management systems programs

    SciTech Connect

    Naser, J.; Gray, S.; Machiels, A.

    1997-12-01

    The Advanced Light Water Reactor (ALWR) Program started in the early 1980`s. This work involves the development and NRC review of the ALWR Utility Requirements Documents, the development and design certification of ALWR designs, the analysis of the Early Site Permit process, and the First-of-a-Kind Engineering for two of the ALWR plant designs. ALWRs will embody modern proven technology. However, technologies expected to be used in these plants are changing very rapidly so that additional capabilities will become available that will be beneficial for future plants. To remain competitive on a life-cycle basis in the future, the ALWR must take advantage of the best and most modem technologies available. 1 ref.

  3. Recent Advances in Understanding and Managing Tourette Syndrome.

    PubMed

    Thenganatt, Mary Ann; Jankovic, Joseph

    2016-01-01

    Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment, discomfort, self-injury, and interference with daily functioning and school or work performance. In addition to tics, most patients with TS have a variety of behavioral comorbidities, including attention deficit hyperactivity disorder and obsessive-compulsive disorder. Studies evaluating the pathophysiology of tics have pointed towards dysfunction of the cortico-striato-thalamo-cortical circuit, but the mechanism of this hyperkinetic movement disorder is not well understood. Treatment of TS is multidisciplinary, typically involving behavioral therapy, oral medications, and botulinum toxin injections. Deep brain stimulation may be considered for "malignant" TS that is refractory to conventional therapy. In this review, we will highlight recent developments in the understanding and management strategies of TS. PMID:26918185

  4. Biology and management of palm dynastid beetles: recent advances.

    PubMed

    Bedford, Geoffrey O

    2013-01-01

    Coconut, oil, and date palms are important crops in the tropics and are attacked by dynastids that cause loss of production or death of hosts. Knowledge of their breeding sites has been extended since a previous review in 1980. The fungus Metarhizium anisopliae has potential as a biopesticide against immature stages in friable breeding sites. The molecular biology and ultrastructure of Oryctes rhinoceros Nudivirus (OrNV), disseminated by adults, have been studied, and this pathogen can reduce O. rhinoceros populations and damage when introduced into new locations, especially where damage had been high. New PCR techniques may enable reliable quantification of dosages ingested and hence virulence of different isolates. Male-produced aggregation pheromones have been identified in several species, for which they may have management potential, having been used commercially for trapping O. rhinoceros in oil palm plantations in Southeast Asia, and tested against O. monoceros in Africa. PMID:23317044

  5. Advances in Diagnosis and Management of Salivary Gland Diseases

    PubMed Central

    Rice, Dale H.

    1984-01-01

    Salivary glands may be involved in a wide variety of diseases, which may be broadly grouped into (1) inflammatory, (2) noninflammatory, nonneoplastic and (3) neoplastic categories. Most inflammatory and noninflammatory, nonneoplastic diseases should be managed conservatively and symptomatically. The common exceptions are first-arch branchialcleft cysts and calculi. Neoplastic lesions always require resection if that is feasible. For benign tumors, simple excision with a cuff of normal tissue around it will usually suffice. The prevailing trend for treatment of malignant neoplasms is conservatism. No longer is the facial nerve routinely sacrificed. The resection done is dictated by the tumor size and the facial nerve is spared unless directly invaded. Postoperative radiation therapy is increasingly used. PMID:6328773

  6. Advances in the Management of Meconium Aspiration Syndrome

    PubMed Central

    Swarnam, Kamala; Soraisham, Amuchou S.; Sivanandan, Sindhu

    2012-01-01

    Meconium aspiration syndrome (MAS) is a common cause of severe respiratory distress in term infants, with an associated highly variable morbidity and mortality. MAS results from aspiration of meconium during intrauterine gasping or during the first few breaths. The pathophysiology of MAS is multifactorial and includes acute airway obstruction, surfactant dysfunction or inactivation, chemical pneumonitis with release of vasoconstrictive and inflammatory mediators, and persistent pulmonary hypertension of newborn (PPHN). This disorder can be life threatening, often complicated by respiratory failure, pulmonary air leaks, and PPHN. Approaches to the prevention of MAS have changed over time with collaboration between obstetricians and pediatricians forming the foundations for care. The use of surfactant and inhaled nitric oxide (iNO) has led to the decreased mortality and the need for extracorporeal membrane oxygenation (ECMO) use. In this paper, we review the current understanding of the pathophysiology and management of MAS. PMID:22164183

  7. Recent Advances in Understanding and Managing Tourette Syndrome

    PubMed Central

    Thenganatt, Mary Ann; Jankovic, Joseph

    2016-01-01

    Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment, discomfort, self-injury, and interference with daily functioning and school or work performance. In addition to tics, most patients with TS have a variety of behavioral comorbidities, including attention deficit hyperactivity disorder and obsessive-compulsive disorder. Studies evaluating the pathophysiology of tics have pointed towards dysfunction of the cortico-striato-thalamo-cortical circuit, but the mechanism of this hyperkinetic movement disorder is not well understood. Treatment of TS is multidisciplinary, typically involving behavioral therapy, oral medications, and botulinum toxin injections. Deep brain stimulation may be considered for “malignant” TS that is refractory to conventional therapy. In this review, we will highlight recent developments in the understanding and management strategies of TS. PMID:26918185

  8. Recent advances in diagnosis and management of hypertrophic cardiomyopathy

    PubMed Central

    Siswanto, B B; Aryani, R

    2009-01-01

    Hypertrophic cardiomyopathy (HCM) is characterised by a thickened but non-dilated left ventricle in the absence of another cardiac or systemic condition capable of producing the magnitude of hypertrophy evident. It is the most common familial genetic disease of the heart (1/500 to 1/1000), as well as the most common cause of sudden cardiac death in young people and athletes. Survival rates of patients with HCM have improved from the 1960s onwards. Natural history in patients with HCM might vary from developing severe heart failure or atrial fibrillation, some die suddenly, often at a young age and in the absence of previous symptoms. Because of its heterogeneous clinical course and expression, HCM frequently presents uncertainty and represents a management dilemma to cardiovascular specialists and other practitioners.

  9. Underground storage tank management plan, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    1997-09-01

    The Underground Storage Tank (UST) Program at the Oak Ridge Y-12 Plant was established to locate UST systems at the facility and to ensure that all operating UST systems are free of leaks. UST systems have been removed or upgraded in accordance with Tennessee Department of Environment and Conservation (TDEC) regulations and guidance. With the closure of a significant portion of the USTs, the continuing mission of the UST Management Program is to manage the remaining active UST systems and continue corrective actions in a safe regulatory compliant manner. This Program outlines the compliance issues that must be addressed, reviews the current UST inventory and compliance approach, and presents the status and planned activities associated with each UST system. The UST Program provides guidance for implementing TDEC regulations and guidelines for petroleum UST systems. The plan is divided into three major sections: (1) regulatory requirements, (2) active UST sites, and (3) out-of-service UST sites. These sections describe in detail the applicable regulatory drivers, the UST sites addressed under the Program, and the procedures and guidance for compliance.

  10. 40 CFR Table 1 to Subpart Bbbbbb... - Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 14 2010-07-01 2010-07-01 false Applicability Criteria, Emission Limits, and Management Practices for Storage Tanks 1 Table 1 to Subpart BBBBBB of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR...

  11. Antiplatelet Management for Coronary Heart Disease: Advances and Challenges.

    PubMed

    Gillette, Michael; Morneau, Kathleen; Hoang, Vu; Virani, Salim; Jneid, Hani

    2016-06-01

    Coronary heart disease (CHD) remains the leading cause of death in the USA. CHD accounts for 48 % of all cardiovascular mortality or approximately one of every seven deaths. Disruption of atherosclerotic plaques-usually by rupture or erosion-and superimposed thrombosis can result in acute coronary syndromes and sudden cardiac death. Silent plaque disruption may also occur and result in coronary plaque progression and ultimately the symptomatic manifestations of stable CHD. Antiplatelet agents remain the cornerstone therapy for acute thrombotic coronary syndromes and are essential for thromboprophylaxis against these events in patients with stable CHD. Antiplatelet drugs are also important adjunct therapies during percutaneous coronary intervention (PCI) as they mitigate equipment-associated thrombotic complications that are partially induced by iatrogenic plaque rupture by interventionalists during balloon angioplasty in the cardiac catheterization laboratory. Since the introduction of clopidogrel, there has been considerable development in this field with at least three novel P2Y12 antagonists approved by the Food and Drug Administration (FDA) over the past decade. Rapidly accumulating evidence is helping to guide the optimal duration of treatment with dual antiplatelet therapy after stenting, especially with the newer drug-eluting stents. More data are also emerging on the hazards and long-term safety of these agents. It is therefore prudent for clinicians to remain current on treatment options and recent advances in this area. We herein review current and emerging antiplatelet therapies and summarize their characteristics and indications of use as well as challenges and areas of ongoing research. PMID:27139709

  12. Pathophysiology and recent advances in the management of renal osteodystrophy.

    PubMed

    Elder, Grahame

    2002-12-01

    Bone disease is observed in 75-100% of patients with chronic renal failure as the glomerular filtration rate (GFR) falls below 60 ml/minute. Hyperparathyroid (high turnover) bone disease is found most frequently followed by mixed osteodystrophy, low-turnover bone disease, and osteomalacia. With advancing renal impairment, "skeletal resistance" to parathyroid hormone (PTH) occurs. To maintain bone turnover, intact PTH (iPTH) targets from two to four times the upper normal range have been suggested, but whole PTH(1-84) assays indicate that amino-terminally truncated fragments, which accumulate in end-stage renal disease (ESRD), account for up to one-half of the measured iPTH. PTH levels and bone-specific alkaline phosphatase (BSAP) provide some information on bone involvement but bone biopsy and histomorphometry remains the gold standard. Calcitriol and calcium salts can be used to suppress PTH and improve osteomalacia but there is growing concern that these agents predispose to the development of vascular calcification, cardiovascular morbidity, low-turnover bone disease and fracture. Newer therapeutic options include less calcemic vitamin D analogues, calcimimetics and bisphosphonates for hyperparathyroidism, and sevelamer for phosphate control. Calcitriol and hormone-replacement therapy (HRT) have been shown to maintain bone mineral density (BMD) in certain patients with end-stage renal disease (ESRD). After renal transplantation, renal osteodystrophy generally improves but BMD often worsens. Bisphosphonate therapy may be appropriate for some patients at risk of fracture. When renal bone disease is assessed using a combination of biochemical markers, histology and bone densitometry, early intervention and the careful use of an increasing number of effective therapies can reduce the morbidity associated with this common problem. PMID:12469904

  13. Optical Storage Systems for Records and Information Management: Overview, Recommendations and Guidelines for Local Governments. Local Government Records Technical Information Series. Number 45.

    ERIC Educational Resources Information Center

    Schwartz, Stanley F.

    This publication discusses optical storage, a term encompassing technologies that use laser-produced light to record and store information in digital form. The booklet also discusses how optical storage systems relate to records management, in particular to the management of local government records in New York State. It describes components of…

  14. Identification of salt-alloy combinations for thermal energy storage applications in advanced solar dynamic power systems

    NASA Technical Reports Server (NTRS)

    Whittenberger, J. D.; Misra, A. K.

    1987-01-01

    Thermodynamic calculations based on the available data for flouride salt systems reveal that a number of congruently melting compositions and eutectics exist which have the potential to meet the lightweight, high energy storage requirements imposed for advanced solar dynamic systems operating between about 1000 and 1400 K. Compatibility studies to determine suitable containment alloys to be used with NaF-22CaF2-13MgF2, NaF-32CaF2, and NaF-23MgF2 have been conducted at the eutectic temperature + 25 K for each system. For these three NaF-based eutectics, none of the common, commercially available high temperature alloys appear to offer adequate corrosion resistance for a long lifetime; however mild steel, pure nickel and Nb-1Zr could prove useful. These latter materials suggest the possibility that a strong, corrosion resistant, nonrefractory, elevated temperature alloy based on the Ni-Ni3Nb system could be developed.

  15. Wireless Sensors and Networks for Advanced Energy Management

    SciTech Connect

    Hardy, J.E.

    2005-05-06

    Numerous national studies and working groups have identified low-cost, very low-power wireless sensors and networks as a critical enabling technology for increasing energy efficiency, reducing waste, and optimizing processes. Research areas for developing such sensor and network platforms include microsensor arrays, ultra-low power electronics and signal conditioning, data/control transceivers, and robust wireless networks. A review of some of the research in the following areas will be discussed: (1) Low-cost, flexible multi-sensor array platforms (CO{sub 2}, NO{sub x}, CO, humidity, NH{sub 3}, O{sub 2}, occupancy, etc.) that enable energy and emission reductions in applications such as buildings and manufacturing; (2) Modeling investments (energy usage and savings to drive capital investment decisions) and estimated uptime improvements through pervasive gathering of equipment and process health data and its effects on energy; (3) Robust, self-configuring wireless sensor networks for energy management; and (4) Quality-of-service for secure and reliable data transmission from widely distributed sensors. Wireless communications is poised to support technical innovations in the industrial community, with widespread use of wireless sensors forecasted to improve manufacturing production and energy efficiency and reduce emissions. Progress being made in wireless system components, as described in this paper, is helping bring these projected improvements to reality.

  16. Recent advances in the management of venous thromboembolism

    PubMed Central

    2010-01-01

    Venous thromboembolism (VTE) is a spectrum of diseases that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Anticoagulant treatment is the mainstay of therapy for VTE. Unfractionated heparin (UFH) or low molecular weight heparin (LMWH) followed by vitamin K antagonists have been the treatment of choice for most patients with VTE, with the aim to prevent thrombus extension or embolization and recurrent VTE. Fondaparinux, a selective, indirect, parenteral factor Xa inhibitor, is now also approved for the initial treatment of VTE and represents an important alternative to UFH or LMWH. Secondary prevention of VTE with vitamin K antagonists is usually prescribed for a minimum of three months, with the duration of treatment based on the presence or absence of major identifiable risk factors for the index event. Patients with permanent risk factors or patients with recurrent DVT or PE require life long secondary prevention. Over the last years, new oral anticoagulant agents have been developed and are now undergoing extensive clinical evaluation in several settings, including the treatment of VTE. New oral anticoagulants include selective, direct thrombin inhibitors, such as dabigatran etexilate, and selective, direct factor Xa inhibitos, such as rivaroxaban, apixaban or edoxaban. All these drugs are admistered at fixed daily doses and do not require laboratory monitoring. The positive results of the first completed clinical trials suggest that a new era in the management of VTE is about to begin. PMID:21120157

  17. Advances in cirrhosis: Optimizing the management of hepatic encephalopathy.

    PubMed

    Liu, Andy; Perumpail, Ryan B; Kumari, Radhika; Younossi, Zobair M; Wong, Robert J; Ahmed, Aijaz

    2015-12-18

    Hepatic encephalopathy (HE) is a major complication of cirrhosis resulting in significant socioeconomic burden, morbidity, and mortality. HE can be further subdivided into covert HE (CHE) and overt HE (OHE). CHE is a subclinical, less severe manifestation of HE and requires psychometric testing for diagnosis. Due to the time consuming screening process and lack of standardized diagnostic criteria, CHE is frequently underdiagnosed despite its recognized role as a precursor to OHE. Screening for CHE with the availability of the Stroop test has provided a pragmatic method to promptly diagnose CHE. Management of acute OHE involves institution of lactulose, the preferred first-line therapy. In addition, prompt recognition and treatment of precipitating factors is critical as it may result in complete resolution of acute episodes of OHE. Treatment goals include improvement of daily functioning, evaluation for liver transplantation, and prevention of OHE recurrence. For secondary prophylaxis, intolerance to indefinite lactulose therapy may lead to non-adherence and has been identified as a precipitating factor for recurrent OHE. Rifaximin is an effective add-on therapy to lactulose for treatment and prevention of recurrent OHE. Recent studies have demonstrated comparable efficacy of probiotic therapy to lactulose use in both primary prophylaxis and secondary prophylaxis. PMID:26692331

  18. Advances in Data Management in Remote Sensing and Climate Modeling

    NASA Astrophysics Data System (ADS)

    Brown, P. G.

    2014-12-01

    Recent commercial interest in "Big Data" information systems has yielded little more than a sense of deja vu among scientists whose work has always required getting their arms around extremely large databases, and writing programs to explore and analyze it. On the flip side, there are some commercial DBMS startups building "Big Data" platform using techniques taken from earth science, astronomy, high energy physics and high performance computing. In this talk, we will introduce one such platform; Paradigm4's SciDB, the first DBMS designed from the ground up to combine the kinds of quality-of-service guarantees made by SQL DBMS platforms—high level data model, query languages, extensibility, transactions—with the kinds of functionality familiar to scientific users—arrays as structural building blocks, integrated linear algebra, and client language interfaces that minimize the learning curve. We will review how SciDB is used to manage and analyze earth science data by several teams of scientific users.

  19. Thermal management of advanced fuel cell power systems

    NASA Technical Reports Server (NTRS)

    Vanderborgh, N. E.; Hedstrom, J.; Huff, J.

    1990-01-01

    It is shown that fuel cell devices are particularly attractive for the high-efficiency, high-reliability space hardware necessary to support upcoming space missions. These low-temperature hydrogen-oxygen systems necessarily operate with two-phase water. In either PEMFCs (proton exchange membrane fuel cells) or AFCs (alkaline fuel cells), engineering design must be critically focused on both stack temperature control and on the relative humidity control necessary to sustain appropriate conductivity within the ionic conductor. Water must also be removed promptly from the hardware. Present designs for AFC space hardware accomplish thermal management through two coupled cooling loops, both driven by a heat transfer fluid, and involve a recirculation fan to remove water and heat from the stack. There appears to be a certain advantage in using product water for these purposes within PEM hardware, because in that case a single fluid can serve both to control stack temperature, operating simultaneously as a heat transfer medium and through evaporation, and to provide the gas-phase moisture levels necessary to set the ionic conductor at appropriate performance levels. Moreover, the humidification cooling process automatically follows current loads. This design may remove the necessity for recirculation gas fans, thus demonstrating the long-term reliability essential for future space power hardware.

  20. Advances in cirrhosis: Optimizing the management of hepatic encephalopathy

    PubMed Central

    Liu, Andy; Perumpail, Ryan B; Kumari, Radhika; Younossi, Zobair M; Wong, Robert J; Ahmed, Aijaz

    2015-01-01

    Hepatic encephalopathy (HE) is a major complication of cirrhosis resulting in significant socioeconomic burden, morbidity, and mortality. HE can be further subdivided into covert HE (CHE) and overt HE (OHE). CHE is a subclinical, less severe manifestation of HE and requires psychometric testing for diagnosis. Due to the time consuming screening process and lack of standardized diagnostic criteria, CHE is frequently underdiagnosed despite its recognized role as a precursor to OHE. Screening for CHE with the availability of the Stroop test has provided a pragmatic method to promptly diagnose CHE. Management of acute OHE involves institution of lactulose, the preferred first-line therapy. In addition, prompt recognition and treatment of precipitating factors is critical as it may result in complete resolution of acute episodes of OHE. Treatment goals include improvement of daily functioning, evaluation for liver transplantation, and prevention of OHE recurrence. For secondary prophylaxis, intolerance to indefinite lactulose therapy may lead to non-adherence and has been identified as a precipitating factor for recurrent OHE. Rifaximin is an effective add-on therapy to lactulose for treatment and prevention of recurrent OHE. Recent studies have demonstrated comparable efficacy of probiotic therapy to lactulose use in both primary prophylaxis and secondary prophylaxis. PMID:26692331

  1. Advances in the management of patients with thyroid disease.

    PubMed

    Dworkin, H J; Meier, D A; Kaplan, M

    1995-07-01

    Discoveries related to thyroid immunology, especially concerning the thyroid-stimulating hormone (TSH) receptor, may facilitate new immunologic approaches to the therapy of Graves' disease and the thyroiditis syndromes. Advances in genetics are being applied to the thyroid hormone resistance syndromes and papillary and medullary carcinomas. The development of ever more sensitive TSH assays has led to the detection of subclinical thyroid disease, which has special implications for the sick and elderly patients. Sensitive TSH assays also allow more precise titration of levothyroxine (T4) dosages, especially for patients with a past history of thyroid cancer. Evidence continues to accumulate suggesting that postmenopausal women on T4 doses that suppress the TSH level below 0.1 ulU/mL have lower bone mineral density than matched patients with healthy TSH levels. Also, pregnant hypothyroid women need higher T4 doses to normalize the TSH levels. In the evaluation of thyroid nodules, fine-needle aspiration biopsy is the single most definitive modality in selecting the patients for surgery. Scintigraphy provides a complimentary role, especially in defining autonomously functioning thyroid adenomas (AFTA), because these should not be treated with T4 suppression. Ultrasound-guided needle biopsy is occasionally helpful with nodules that are difficult to palpate. Concern for possible tracheal compression after treatment of toxic multinodular goiter with large doses of radioactive iodine (I-131) in the range of 50 to 150 mCi (1.85 to 5.5 GBq) does not seem warranted. Work, primarily out of Italy, suggests AFTA can be ablated with repeat ethanol injections. Residual tissues after thyroidectomy for differentiated carcinoma can be "stunned" by tracer doses of 131I greater than 3.0 mCi (111 MBq), which diminishes the uptake and effectiveness of a subsequent therapy dose. Positron emission tomograph, imaging with thallium-201, and Technetium 99m Sestamibi can identify a small number

  2. Vegetation persistence and carbon storage: Implications for environmental water management for Phragmites australis

    NASA Astrophysics Data System (ADS)

    Whitaker, Kai; Rogers, Kerrylee; Saintilan, Neil; Mazumder, Debashish; Wen, Li; Morrison, R. J.

    2015-07-01

    Environmental water allocations are used to improve the ecological health of wetlands. There is now increasing demand for allocations to improve ecosystem productivity and respiration, and enhance carbon sequestration. Despite global recognition of wetlands as carbon sinks, information regarding carbon dynamics is lacking. This is the first study estimating carbon sequestration for semiarid Phragmites australis reedbeds. The study combined aboveground biomass assessments with stable isotope analyses of soils and modeling of biomass using Normalized Digital Vegetation Index (NDVI) to investigate the capacity of environmental water allocations to improve carbon storage. The study considered relationships between soil organic carbon (SOC), carbon sources, and reedbed persistence in the Macquarie Marshes, a regulated semiarid floodplain of the Murray-Darling Basin, Australia. SOC storage levels to 1 m soil depth were higher in persistent reedbeds (167 Mg ha-1) than ephemeral reedbeds (116-138 Mg ha-1). In situ P. australis was the predominant source of surface SOC at persistent reedbeds; mixed sources of surface SOC were proposed for ephemeral reedbeds. 13C enrichment with increasing soil depth occurred in persistent and ephemeral reedbeds and may not relate to flow characteristics. Despite high SOC at persistent reedbeds, differences in the rate of accretion contributed to significantly higher rates of carbon sequestration at ephemeral reedbeds (approximately 554 and 465 g m-2 yr-1) compared to persistent reedbeds (5.17 g m-2 yr-1). However, under current water regimes, rapid accretion at ephemeral reedbeds cannot be maintained. Effective management of persistent P. australis reedbeds may enhance carbon sequestration in the Macquarie Marshes and floodplain wetlands more generally.

  3. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory... school food authorities must meet the requirements for storage and inventory of donated foods in § 250.14... foods in this part. (c) Storage by school food authorities. The school food authority may store...

  4. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory... school food authorities must meet the requirements for storage and inventory of donated foods in § 250.14... foods in this part. (c) Storage by school food authorities. The school food authority may store...

  5. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory... school food authorities must meet the requirements for storage and inventory of donated foods in § 250.14... foods in this part. (c) Storage by school food authorities. The school food authority may store...

  6. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory... school food authorities must meet the requirements for storage and inventory of donated foods in § 250.14... foods in this part. (c) Storage by school food authorities. The school food authority may store...

  7. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory... school food authorities must meet the requirements for storage and inventory of donated foods in § 250.14... foods in this part. (c) Storage by school food authorities. The school food authority may store...

  8. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.

    PubMed

    Gillessen, S; Omlin, A; Attard, G; de Bono, J S; Efstathiou, E; Fizazi, K; Halabi, S; Nelson, P S; Sartor, O; Smith, M R; Soule, H R; Akaza, H; Beer, T M; Beltran, H; Chinnaiyan, A M; Daugaard, G; Davis, I D; De Santis, M; Drake, C G; Eeles, R A; Fanti, S; Gleave, M E; Heidenreich, A; Hussain, M; James, N D; Lecouvet, F E; Logothetis, C J; Mastris, K; Nilsson, S; Oh, W K; Olmos, D; Padhani, A R; Parker, C; Rubin, M A; Schalken, J A; Scher, H I; Sella, A; Shore, N D; Small, E J; Sternberg, C N; Suzuki, H; Sweeney, C J; Tannock, I F; Tombal, B

    2015-08-01

    The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged. PMID:26041764

  9. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

    PubMed Central

    Gillessen, S.; Omlin, A.; Attard, G.; de Bono, J. S.; Efstathiou, E.; Fizazi, K.; Halabi, S.; Nelson, P. S.; Sartor, O.; Smith, M. R.; Soule, H. R.; Akaza, H.; Beer, T. M.; Beltran, H.; Chinnaiyan, A. M.; Daugaard, G.; Davis, I. D.; De Santis, M.; Drake, C. G.; Eeles, R. A.; Fanti, S.; Gleave, M. E.; Heidenreich, A.; Hussain, M.; James, N. D.; Lecouvet, F. E.; Logothetis, C. J.; Mastris, K.; Nilsson, S.; Oh, W. K.; Olmos, D.; Padhani, A. R.; Parker, C.; Rubin, M. A.; Schalken, J. A.; Scher, H. I.; Sella, A.; Shore, N. D.; Small, E. J.; Sternberg, C. N.; Suzuki, H.; Sweeney, C. J.; Tannock, I. F.; Tombal, B.

    2015-01-01

    The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged. PMID:26041764

  10. Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa.

    PubMed

    Butros, Linda; Boayue, Koh; Mathew, Prasad

    2011-01-01

    Bypassing agents are the mainstay of treatment for patients with hemophilia with high-titer inhibitors. Whereas the availability of these agents has greatly advanced the management of bleeding episodes in this population, timely administration of bypassing agents continues to be hampered by a number of practical limitations, including the need for refrigerated storage of the agent and its reconstitution at room temperature prior to administration, among others. In this review, the importance of early treatment of bleeds and factors that influence this more timely therapeutic approach are highlighted, together with the advantages offered by the use of a new formulation of recombinant activated factor VII that permits improved storage and portability, potentially optimizing timely bypassing agent administration. PMID:21625417

  11. Conceptual design of electrical balance of plant for advanced battery energy storage facility. Annual report, March 1979. [20-MW, 100 MWh

    SciTech Connect

    1980-01-01

    Large-scale efforts are in progress to develop advanced batteries for utility energy storage systems. Realization of the full benefits available from those systems requires development, not only of the batteries themselves, but also the ac/dc power converter, the bulk power interconnecting equipment, and the peripheral electric balance of plant equipment that integrate the battery/converter into a properly controlled and protected energy system. This study addresses these overall system aspects; although tailored to a 20-MW, 100-MWh lithium/sulfide battery system, the technology and concepts are applicable to any battery energy storage system. 42 figures, 14 tables. (RWR)

  12. AN ADVANCED TOOL FOR APPLIED INTEGRATED SAFETY MANAGEMENT

    SciTech Connect

    Potts, T. Todd; Hylko, James M.; Douglas, Terence A.

    2003-02-27

    WESKEM, LLC's Environmental, Safety and Health (ES&H) Department had previously assessed that a lack of consistency, poor communication and using antiquated communication tools could result in varying operating practices, as well as a failure to capture and disseminate appropriate Integrated Safety Management (ISM) information. To address these issues, the ES&H Department established an Activity Hazard Review (AHR)/Activity Hazard Analysis (AHA) process for systematically identifying, assessing, and controlling hazards associated with project work activities during work planning and execution. Depending on the scope of a project, information from field walkdowns and table-top meetings are collected on an AHR form. The AHA then documents the potential failure and consequence scenarios for a particular hazard. Also, the AHA recommends whether the type of mitigation appears appropriate or whether additional controls should be implemented. Since the application is web based, the information is captured into a single system and organized according to the >200 work activities already recorded in the database. Using the streamlined AHA method improved cycle time from over four hours to an average of one hour, allowing more time to analyze unique hazards and develop appropriate controls. Also, the enhanced configuration control created a readily available AHA library to research and utilize along with standardizing hazard analysis and control selection across four separate work sites located in Kentucky and Tennessee. The AHR/AHA system provides an applied example of how the ISM concept evolved into a standardized field-deployed tool yielding considerable efficiency gains in project planning and resource utilization. Employee safety is preserved through detailed planning that now requires only a portion of the time previously necessary. The available resources can then be applied to implementing appropriate engineering, administrative and personal protective equipment

  13. Advances in contraception: IUDs from a managed care perspective.

    PubMed

    Doyle, John; Stern, Lee; Hagan, Michael; Hao, Jiayi; Gricar, Joseph

    2008-01-01

    Contraceptive use in the United States is virtually universal among women of reproductive age. However, unplanned pregnancies continue to occur and can be largely attributed to the nonuse and misuse of contraception. Reducing unintended pregnancies constitutes a critical goal for managed care and the public. This can be achieved in part with intrauterine devices (IUDs), which are an effective method of contraception that require a one-time insertion and stay in place for 5-10 years. Therefore, compliance issues are largely mitigated, and actual use efficacy is the same as perfect use efficacy. The IUD is also reversible, unlike tubal ligation, and could potentially be the contraceptive of choice in today's environment. Unfortunately, safety concerns surrounding the use of older IUDs have precluded many women from recognizing the benefits of their use. Currently, the only approved IUDs in the United States are ParaGard, the copper IUD, and Mirena, the levonorgestrel-releasing intrauterine system (LNG-IUS). These devices offer superior safety profiles compared with those products that were withdrawn from the market in the 1970s. In addition to a favorable safety and tolerability profile, the LNG-IUS offers an advantage over copper IUDs, demonstrating improved efficacy in preventing intrauterine and ectopic pregnancies. Successful communication between patients and providers regarding the improved safety and efficacy of newer IUDs will ensure an appropriate place in therapy. Thus, greater numbers of women will recognize the IUD as a safe, cost-effective means to contraception, thereby reducing the economic and social burdens associated with unplanned pregnancies. PMID:18681819

  14. Highly Automated Module Production Incorporating Advanced Light Management

    SciTech Connect

    Perelli-Minetti, Michael; Roof, Kyle

    2015-08-11

    The objective was to enable a high volume, cost effective solution for increasing the amount of light captured by PV modules through utilization of an advanced Light Re-directing Film and to follow a phased approach to develop and implement this new technology in order to achieve an expected power gain of up to 12 watts per module. Full size PV modules were manufactured using a new Light Redirecting Film (LRF) material applied to two different areas of PV modules in order to increase the amount of light captured by the modules. One configuration involved applying thin strips of LRF film over the tabbing ribbon on the cells in order to redirect the light that is normally absorbed by the tabbing ribbon to the active areas of the cells. A second configuration involved applying thin strips of LRF film over the white spaces between cells within a module in order to capture some of the light that is normally reflected from the white areas back through the front glass of the modules. Significant power increases of 1.4% (3.9 watts) and 1.0% (3.2 watts), respectively, compared to standard PV modules were measured under standard test conditions. The performance of PV modules with LRF applied to the tabbing ribbon was modeled. The results showed that the power increase provided by LRF depended greatly on the angle of incident light with the optimum performance only occurring when the light was within a narrow range of being perpendicular to the solar module. The modeling showed that most of the performance gain would be lost when the angle of incident light was greater than 28 degrees off axis. This effect made the orientation of modules with LRF applied to tabbing ribbons very important as modules mounted in “portrait” mode were predicted to provide little to no power gain from LRF under real world conditions. Based on these results, modules with LRF on tabbing ribbons would have to be mounted in “landscape” mode to realize a performance advantage. In addition

  15. Alternative Fuels and Advanced Vehicles: Resources for Fleet Managers (Clean Cities) (Presentation)

    SciTech Connect

    Brennan, A.

    2011-04-01

    A discussion of the tools and resources on the Clean Cities, Alternative Fuels and Advanced Vehicles Data Center, and the FuelEconomy.gov Web sites that can help vehicle fleet managers make informed decisions about implementing strategies to reduce gasoline and diesel fuel use.

  16. Management and Consumer Education Curriculum Guide. Advanced Unit and Semester Course. Draft.

    ERIC Educational Resources Information Center

    Clemson Univ., SC. Vocational Education Media Center.

    The guide is an attempt to help teachers select content and organize instructions in a sequence that will help students grasp the basic structure of management and consumer education. The guide was written in reference to a norm grouping. The advanced course for grade 10 presents the concepts of decision making and teenager consumership. The…

  17. Planning and Managing Learning Tasks and Activities. Advances in Research on Teaching. Volume 3.

    ERIC Educational Resources Information Center

    Brophy, Jere, Ed.

    This publication is the third volume in the "Advanced in Research on Teaching" series, which has been established to provide state-of-the-art conceptualization and analysis of the processes involved in functioning as a classroom teacher. This volume focuses on the planning and managing of learning tasks and activities, in particular, what is…

  18. Something Ventured, Something Gained. An Advanced Curriculum for Small Business Management. Volume II.

    ERIC Educational Resources Information Center

    Shuchat, Jo; And Others

    Nine units on small business management are provided in this curriculum guide designed for use in an advanced course for secondary and postsecondary students who are interested in beginning a small business venture, have some prior business knowledge, and have a specific business in mind. Unit topics include marketing, location, systems and…

  19. Lake Storage Measurements For Water Resources Management: Combining Remotely Sensed Water Levels and Surface Areas

    NASA Astrophysics Data System (ADS)

    Brakenridge, G. R.; Birkett, C. M.

    2013-12-01

    Presently operating satellite-based radar altimeters have the ability to monitor variations in surface water height for large lakes and reservoirs, and future sensors will expand observational capabilities to many smaller water bodies. Such remote sensing provides objective, independent information where in situ data are lacking or access is restricted. A USDA/NASA (http://www.pecad.fas.usda.gov/cropexplorer/global_reservoir/) program is performing operational altimetric monitoring of the largest lakes and reservoirs around the world using data from the NASA/CNES, NRL, and ESA missions. Public lake-level products from the Global Reservoir and Lake Monitor (GRLM) are a combination of archived and near real time information. The USDA/FAS utilizes the products for assessing international irrigation potential and for crop production estimates; other end-users study climate trends, observe anthropogenic effects, and/or are are involved in other water resources management and regional water security issues. At the same time, the Dartmouth Flood Observatory (http://floodobservatory.colorado.edu/), its NASA GSFC partners (http://oas.gsfc.nasa.gov/floodmap/home.html), and associated MODIS data and automated processing algorithms are providing public access to a growing GIS record of the Earth's changing surface water extent, including changes related to floods and droughts. The Observatory's web site also provide both archival and near real time information, and is based mainly on the highest spatial resolution (250 m) MODIS bands. Therefore, it is now possible to provide on an international basis reservoir and lake storage change measurements entirely from remote sensing, on a frequently updating basis. The volume change values are based on standard numerical procedures used for many decades for analysis of coeval lake area and height data. We provide first results of this combination, including prototype displays for public access and data retrieval of water storage

  20. Overview of advances in water management in agricultural production:Sensor based irrigation management

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Technological advances in irrigated agriculture are crucial to meeting the challenge of increasing demand for agricultural products given limited quality and quantity of water resources for irrigation, impacts of climate variability, and the need to reduce environmental impacts. Multidisciplinary ap...

  1. Advances in the management of Barrett’s esophagus and early esophageal adenocarcinoma

    PubMed Central

    Singh, Ajaypal; Chak, Amitabh

    2015-01-01

    The incidence of esophageal adenocarcinoma (EAC) has markedly increased in the United States over the last few decades. Barrett’s esophagus (BE) is the most significant known risk factor for this malignancy. Theoretically, screening and treating early BE should help prevent EAC but the exact incidence of BE and its progression to EAC is not entirely known and cost-effectiveness studies for Barrett’s screening are lacking. Over the last few years, there have been major advances in our understanding of the epidemiology, pathogenesis and endoscopic management of BE. These developments focus on early recognition of advanced histology and endoscopic treatment of high-grade dysplasia. Advanced resection techniques now enable us to endoscopically treat early esophageal cancer. In this review, we will discuss these recent advances in diagnosis and treatment of Barrett’s esophagus and early esophageal adenocarcinoma. PMID:26486568

  2. Advanced Basal cell carcinoma in a patient with schizoaffective disorder: constraints and management.

    PubMed

    Taylor, Elise J; Golas, Liliya; Martel, Joseph R; Martel, James B

    2013-01-01

    The approach used by the authors for managing a patient with a schizoaffective disorder and advanced basal cell carcinoma involving the eyelids, orbit, and face is presented. Complexities included the advanced nature of the disease, neglect of the patient's condition due to schizoaffective disorder, the difficulty of obtaining informed consent, the required aggressive surgical intervention, reconstruction, and the necessary management during the postsurgical period. A multidisciplinary team approach with psychiatry, ophthalmology, ear, nose, and throat, plastic surgery, radiation oncology, oncology, legal, and bioethics specialties is required in patients with cognitive disabilities. Curative treatment requires complete excision, reconstruction, and proper postoperative care, which can be prohibitive in a schizophrenic patient from a surgical and ethical perspective. Staging of this condition after proper informed consent with biopsy, computed tomography, and magnetic resonance imaging is presented. The options for management are discussed, including surgical intervention and palliative care. PMID:23235512

  3. CMS users data management service integration and first experiences with its NoSQL data storage

    NASA Astrophysics Data System (ADS)

    Riahi, H.; Spiga, D.; Boccali, T.; Ciangottini, D.; Cinquilli, M.; Hernàndez, J. M.; Konstantinov, P.; Mascheroni, M.; Santocchia, A.

    2014-06-01

    The distributed data analysis workflow in CMS assumes that jobs run in a different location to where their results are finally stored. Typically the user outputs must be transferred from one site to another by a dedicated CMS service, AsyncStageOut. This new service is originally developed to address the inefficiency in using the CMS computing resources when transferring the analysis job outputs, synchronously, once they are produced in the job execution node to the remote site. The AsyncStageOut is designed as a thin application relying only on the NoSQL database (CouchDB) as input and data storage. It has progressed from a limited prototype to a highly adaptable service which manages and monitors the whole user files steps, namely file transfer and publication. The AsyncStageOut is integrated with the Common CMS/Atlas Analysis Framework. It foresees the management of nearly nearly 200k users' files per day of close to 1000 individual users per month with minimal delays, and providing a real time monitoring and reports to users and service operators, while being highly available. The associated data volume represents a new set of challenges in the areas of database scalability and service performance and efficiency. In this paper, we present an overview of the AsyncStageOut model and the integration strategy with the Common Analysis Framework. The motivations for using the NoSQL technology are also presented, as well as data design and the techniques used for efficient indexing and monitoring of the data. We describe deployment model for the high availability and scalability of the service. We also discuss the hardware requirements and the results achieved as they were determined by testing with actual data and realistic loads during the commissioning and the initial production phase with the Common Analysis Framework.

  4. Pomological and nutraceutical properties in apricot fruit: cultivation systems and cold storage fruit management.

    PubMed

    Leccese, Annamaria; Bureau, Sylvie; Reich, Maryse; Renard, M G C Catherine; Audergon, Jean-Marc; Mennone, Carmelo; Bartolini, Susanna; Viti, Raffaella

    2010-06-01

    We have investigated the effect of cultivation systems and fruit post-harvest management on the antioxidant properties of apricot fruits. Trees of five cultivars 'Tyrinthos', 'Cafona', 'Bella d'Italia', 'Vitillo' and 'Pellecchiella' were cultivated under integrated and organic systems. Fruits were collected at full maturity stage and analyzed either immediately or after storage at 4+/-0.5 degrees C and 85% of relative humidity for seven and 14 days. The main pomological traits (weight, colour, flesh firmness, total soluble sugars, titratable acidity) and antioxidant properties were analyzed. The total antioxidant capacity (TAC by TEAC method), total phenols content (TP by Folin-Ciocalteu method) and carotenoid content by HPLC-DAD were monitored. Cultivar characterization by principal component analysis (PCA) indicated a large variability on pomological and antioxidant properties of apricot fruits. 'Bella d'Italia' showed better TAC and TP values compared to the other cultivars. ANOVA interactions between cultivar and cultivation system (organic/integrated) were found for the antioxidant properties. These interactions may help to select a set of genotypes with better performances under organic system, which in our study might be indicated in 'Cafona' and 'Bella d'Italia'. PMID:20198441

  5. A Risk Management Method for the Operation of a Supply-Chain without Storage:

    NASA Astrophysics Data System (ADS)

    Kobayashi, Yasuhiro; Manabe, Yuuji; Nakata, Norimasa; Kusaka, Satoshi

    A business risk management method has been developed for a supply-chain without a storage function under demand uncertainty. Power supply players in the deregulated power market face the need to develop the best policies for power supply from self-production and reserved purchases to balance demand, which is predictable with error. The proposed method maximizes profit from the operation of the supply-chain under probabilistic demand uncertainty on the basis of a probabilistic programming approach. Piece-wise linear functions are employed to formulate the impact of under-booked or over-booked purchases on the supply cost, and constraints on over-demand probability are introduced to limit over-demand frequency on the basis of the demand probability distribution. The developed method has been experimentally applied to the supply policy of a power-supply-chain, the operation of which is based on a 3-stage pricing purchase contract and on 28 time zones. The characteristics of the obtained optimal supply policy are successfully captured in the numerical results, which suggest the applicability of the proposed method.

  6. Risk perception on management of nuclear high-level and transuranic waste storage

    SciTech Connect

    Dees, L.A.

    1994-08-15

    The Department of Energy`s program for disposing of nuclear High-Level Waste (HLW) and transuranic (TRU) waste has been impeded by overwhelming political opposition fueled by public perceptions of actual risk. Analysis of these perceptions shows them to be deeply rooted in images of fear and dread that have been present since the discovery of radioactivity. The development and use of nuclear weapons linked these images to reality and the mishandling of radioactive waste from the nations military weapons facilities has contributed toward creating a state of distrust that cannot be erased quickly or easily. In addition, the analysis indicates that even the highly educated technical community is not well informed on the latest technology involved with nuclear HLW and TRU waste disposal. It is not surprising then, that the general public feels uncomfortable with DOE`s management plans for with nuclear HLW and TRU waste disposal. Postponing the permanent geologic repository and use of Monitored Retrievable Storage (MRS) would provide the time necessary for difficult social and political issues to be resolved. It would also allow time for the public to become better educated if DOE chooses to become proactive.

  7. THE WIDE-AREA ENERGY STORAGE AND MANAGEMENT SYSTEM PHASE II Final Report - Flywheel Field Tests

    SciTech Connect

    Lu, Ning; Makarov, Yuri V.; Weimar, Mark R.; Rudolph, Frank; Murthy, Shashikala; Arseneaux, Jim; Loutan, Clyde; Chowdhury, S.

    2010-08-31

    This research was conducted by Pacific Northwest National Laboratory (PNNL) operated for the U.S. department of Energy (DOE) by Battelle Memorial Institute for Bonneville Power Administration (BPA), California Institute for Energy and Environment (CIEE) and California Energy Commission (CEC). A wide-area energy management system (WAEMS) is a centralized control system that operates energy storage devices (ESDs) located in different places to provide energy and ancillary services that can be shared among balancing authorities (BAs). The goal of this research is to conduct flywheel field tests, investigate the technical characteristics and economics of combined hydro-flywheel regulation services that can be shared between Bonneville Power Administration (BPA) and California Independent System Operator (CAISO) controlled areas. This report is the second interim technical report for Phase II of the WAEMS project. This report presents: 1) the methodology of sharing regulation service between balancing authorities, 2) the algorithm to allocate the regulation signal between the flywheel and hydro power plant to minimize the wear-and-tear of the hydro power plants, 3) field results of the hydro-flywheel regulation service (conducted by the Beacon Power), and 4) the performance metrics and economic analysis of the combined hydro-flywheel regulation service.

  8. Cryogenic Propellant Storage and Transfer Technology Demonstration: Advancing Technologies for Future Mission Architectures Beyond Low Earth Orbit

    NASA Technical Reports Server (NTRS)

    Chojnacki, Kent T.; Crane, Deborah J.; Motil, Susan M.; Ginty, Carol A.; Tofil, Todd A.

    2014-01-01

    As part of U.S. National Space Policy, NASA is seeking an innovative path for human space exploration, which strengthens the capability to extend human and robotic presence throughout the solar system. NASA is laying the groundwork to enable humans to safely reach multiple potential destinations, including the Moon, asteroids, Lagrange points, and Mars and its environs. In support of this, NASA is embarking on the Technology Demonstration Mission Cryogenic Propellant Storage and Transfer (TDM CPST) Project to test and validate key cryogenic capabilities and technologies required for future exploration elements, opening up the architecture for large cryogenic propulsion stages and propellant depots. The TDM CPST will provide an on-orbit demonstration of the capability to store, transfer, and measure cryogenic propellants for a duration that enables long term human space exploration missions beyond low Earth orbit. This paper will present a summary of the cryogenic fluid management technology maturation effort, infusion of those technologies into flight hardware development, and a summary of the CPST preliminary design.

  9. Software for Storage and Management of Microclimatic Data for Preventive Conservation of Cultural Heritage

    PubMed Central

    Fernández-Navajas, Ángel; Merello, Paloma; Beltrán, Pedro; García-Diego, Fernando-Juan

    2013-01-01

    Cultural Heritage preventive conservation requires the monitoring of the parameters involved in the process of deterioration of artworks. Thus, both long-term monitoring of the environmental parameters as well as further analysis of the recorded data are necessary. The long-term monitoring at frequencies higher than 1 data point/day generates large volumes of data that are difficult to store, manage and analyze. This paper presents software which uses a free open source database engine that allows managing and interacting with huge amounts of data from environmental monitoring of cultural heritage sites. It is of simple operation and offers multiple capabilities, such as detection of anomalous data, inquiries, graph plotting and mean trajectories. It is also possible to export the data to a spreadsheet for analyses with more advanced statistical methods (principal component analysis, ANOVA, linear regression, etc.). This paper also deals with a practical application developed for the Renaissance frescoes of the Cathedral of Valencia. The results suggest infiltration of rainwater in the vault and weekly relative humidity changes related with the religious service schedules. PMID:23447005

  10. Synchrotron-based Infrared-microspectroscopy reveals the impact of land management on carbon storage in soil micro-aggregates

    NASA Astrophysics Data System (ADS)

    Hernandez-Soriano, Maria C.; Dalal, Ram C.; Menzies, Neal W.; Kopittke, Peter M.

    2015-04-01

    responsible for carbon stabilization. A substantial decrease in carboxylic compounds was observed for agricultural soils. Clays were mostly co-localized with alkenes and polysaccharides, particularly in agricultural soils, likely due to enhanced microbial activity in those spots. Results will be linked to currently ongoing analysis of soil enzymes activities and characterization of dissolved organic carbon components. This novel methodological approach combines biological and chemical information on organic carbon dynamics in soil at a molecular level and will constitute a substantial advance towards understanding carbon storage in soil and the long term impact of land management.

  11. Program definition and assessment overview. [for thermal energy storage project management

    NASA Technical Reports Server (NTRS)

    Gordon, L. H.

    1980-01-01

    The implementation of a program level assessment of thermal energy storage technology thrusts for the near and far term to assure overall coherent energy storage program is considered. The identification and definition of potential thermal energy storage applications, definition of technology requirements, and appropriate market sectors are discussed along with the necessary coordination, planning, and preparation associated with program reviews, workshops, multi-year plans and annual operating plans for the major laboratory tasks.

  12. Advanced building energy management system demonstration for Department of Defense buildings.

    PubMed

    O'Neill, Zheng; Bailey, Trevor; Dong, Bing; Shashanka, Madhusudana; Luo, Dong

    2013-08-01

    This paper presents an advanced building energy management system (aBEMS) that employs advanced methods of whole-building performance monitoring combined with statistical methods of learning and data analysis to enable identification of both gradual and discrete performance erosion and faults. This system assimilated data collected from multiple sources, including blueprints, reduced-order models (ROM) and measurements, and employed advanced statistical learning algorithms to identify patterns of anomalies. The results were presented graphically in a manner understandable to facilities managers. A demonstration of aBEMS was conducted in buildings at Naval Station Great Lakes. The facility building management systems were extended to incorporate the energy diagnostics and analysis algorithms, producing systematic identification of more efficient operation strategies. At Naval Station Great Lakes, greater than 20% savings were demonstrated for building energy consumption by improving facility manager decision support to diagnose energy faults and prioritize alternative, energy-efficient operation strategies. The paper concludes with recommendations for widespread aBEMS success. PMID:23808808

  13. Pre-hospital advanced airway management by anaesthesiologists: Is there still room for improvement?

    PubMed Central

    Sollid, Stephen JM; Heltne, Jon Kenneth; Søreide, Eldar; Lossius, Hans Morten

    2008-01-01

    Background Endotracheal intubation is an important part of pre-hospital advanced life support that requires training and experience, and should only be performed by specially trained personnel. In Norway, anaesthesiologists serve as Helicopter Emergency Medical Service HEMS physicians. However, little is known about how they themselves evaluate the quality and safety of pre-hospital advanced airway management. Method Using a semi-structured questionnaire, we interviewed anaesthesiologists working in the three HEMS programs covering Western Norway. We compared answers from specialists and non-specialists as well as full- and part-time HEMS physicians. Results Of the 17 available respondents, most (88%) felt that their continuous exposure to intubations was not sufficient. Additional training was mainly acquired through other clinical practice and mannequin- or cadaver-based skills training. Of the respondents, 77% and 35% reported having experienced difficult and failed intubations, respectively. Further, 59% reported knowledge of airway management-related deaths in their HEMS program. Significantly more full- than part-time HEMS physicians had experienced these problems. All respondents had airway back-up equipment in their service, but 29% were not familiar with all the equipment. Conclusion The majority of anaesthesiologists working as HEMS physicians view pre-hospital advanced airway management as a high-risk procedure. Relevant airway management competencies for HEMS physicians in Norway seem to be insufficiently trained and maintained. A better-defined level of competence with better training methods and systems seems warranted. PMID:18957064

  14. Radiotherapy for the management of locally advanced squamous cell carcinoma of the head and neck

    PubMed Central

    Ko, Christine; Citrin, Deborah

    2008-01-01

    Background Squamous cell carcinomas of the head and neck (SCCHN) affect approximately 35,000 people in the United States yearly. Although survival has improved with advances in therapy, patients with advanced stages of SCCHN continue to have a poor prognosis. An understanding of rationale for treatment selection, newer developments in therapy, and treatment toxicity is critical. Methods Standard methods of treating locally advanced SCCHN are reviewed. Advances in medical and radiotherapeutic management are discussed and the toxicities of therapy are described. Results Post-operative chemoradiation is used in patients with high risk characteristics. Induction chemotherapy and altered fractionation radiation treatment have been evaluated as alternatives to definitive chemo-radiotherapy. Targeted agents such as cetuximab may prove to increase survival with minimal increase in toxicity profile. Technological improvements such as the use of intensity modulated radiation treatment (IMRT) have proven to decrease some debilitating side effects from radiation treatment. Conclusions Locally advanced SCCHN continues to present a therapeutic challenge. Survival, local control, and quality of life are all goals of treatment. The optimal method of treating locally advanced SCCHN is the subject of ongoing research. Long term side effects can be minimized with the use of newer technologies and with careful treatment planning. PMID:19036056

  15. IPAD 2: Advances in Distributed Data Base Management for CAD/CAM

    NASA Technical Reports Server (NTRS)

    Bostic, S. W. (Compiler)

    1984-01-01

    The Integrated Programs for Aerospace-Vehicle Design (IPAD) Project objective is to improve engineering productivity through better use of computer-aided design and manufacturing (CAD/CAM) technology. The focus is on development of technology and associated software for integrated company-wide management of engineering information. The objectives of this conference are as follows: to provide a greater awareness of the critical need by U.S. industry for advancements in distributed CAD/CAM data management capability; to present industry experiences and current and planned research in distributed data base management; and to summarize IPAD data management contributions and their impact on U.S. industry and computer hardware and software vendors.

  16. Effects of increasing forest plantation area and management practices on carbon storage and water use in the United States

    NASA Astrophysics Data System (ADS)

    Chen, G.; Hayes, D. J.; Tian, H.

    2013-12-01

    Planted forest area in the United States gradually increased during the last half century, and by 2007 accounted for about 20% of the total forest area in the southern United States and about 13% in the entire country. Intensive plantation management activities - such as slash burning, thinning, weed control, fertilization and the use of genetically improved seedlings - are routinely applied during the forest rotation. However, no comprehensive assessments have been made to examine the impacts of this increased forest plantation area and associated management practices on ecosystem function. In this study, we integrated field measurement data and process-based modeling to quantitatively estimate the changes in carbon storage, nitrogen cycling and water use as influenced by forest plantations in the United States from 1925 to 2007. The results indicated that forest plantations and management practices greatly increased forest productivity, vegetation carbon, and wood product carbon storage in the United States, but slightly reduce soil carbon storage at some areas; however, the carbon sink induced by forest plantations was at the expense of more water use as represented by higher evapotranspiration. Stronger nitrogen and water limitations were found for forest plantations as compared to natural or naturally-regenerated forests.

  17. Progress Towards Prognostic Health Management of Passive Components in Advanced Small Modular Reactors

    SciTech Connect

    Meyer, Ryan M.; Ramuhalli, Pradeep; Hirt, Evelyn H.; Pardini, Allan F.; Suter, Jonathan D.; Prowant, Matthew S.

    2014-08-01

    Sustainable nuclear power to promote energy security and to reduce greenhouse gas emissions are two key national energy priorities. The development of deployable small modular reactors (SMRs) is expected to support these objectives by developing technologies that improve the reliability, sustain safety, and improve affordability of new reactors. Advanced SMRs (AdvSMRs) refer to a specific class of SMRs and are based on modularization of advanced reactor concepts. Prognostic health management (PHM) systems can benefit both the safety and economics of deploying AdvSMRs and can play an essential role in managing the inspection and maintenance of passive components in AdvSMR systems. This paper describes progress on development of a prototypic PHM system for AdvSMR passive components, with thermal creep chosen as the target degradation mechanism.

  18. Advanced transport operating system software upgrade: Flight management/flight controls software description

    NASA Technical Reports Server (NTRS)

    Clinedinst, Winston C.; Debure, Kelly R.; Dickson, Richard W.; Heaphy, William J.; Parks, Mark A.; Slominski, Christopher J.; Wolverton, David A.

    1988-01-01

    The Flight Management/Flight Controls (FM/FC) software for the Norden 2 (PDP-11/70M) computer installed on the NASA 737 aircraft is described. The software computes the navigation position estimates, guidance commands, those commands to be issued to the control surfaces to direct the aircraft in flight based on the modes selected on the Advanced Guidance Control System (AGSC) mode panel, and the flight path selected via the Navigation Control/Display Unit (NCDU).

  19. Human-System Safety Methods for Development of Advanced Air Traffic Management Systems

    SciTech Connect

    Nelson, W.R.

    1999-05-24

    The Idaho National Engineering and Environmental Laboratory (INEEL) is supporting the National Aeronautics and Space Administration in the development of advanced air traffic management (ATM) systems as part of the Advanced Air Transportation Technologies program. As part of this program INEEL conducted a survey of human-system safety methods that have been applied to complex technical systems, to identify lessons learned from these applications and provide recommendations for the development of advanced ATM systems. The domains that were surveyed included offshore oil and gas, commercial nuclear power, commercial aviation, and military. The survey showed that widely different approaches are used in these industries, and that the methods used range from very high-level, qualitative approaches to very detailed quantitative methods such as human reliability analysis (HRA) and probabilistic safety assessment (PSA). In addition, the industries varied widely in how effectively they incorporate human-system safety assessment in the design, development, and testing of complex technical systems. In spite of the lack of uniformity in the approaches and methods used, it was found that methods are available that can be combined and adapted to support the development of advanced air traffic management systems.

  20. Design manual for management of solid by-products from advanced coal technologies

    SciTech Connect

    1994-10-01

    Developing coal conversion technologies face major obstacles in byproduct management. This project has developed several management strategies based on field trials of small-scale landfills in an earlier phase of the project, as well as on published/unpublished sources detailing regulatory issues, current industry practice, and reuse opportunities. Field testing, which forms the basis for several of the disposal alternatives presented in this design manual, was limited to byproducts from Ca-based dry SO{sub 2} control technologies, circulating fluidized bed combustion ash, and bubbling bed fluidized bed combustion ash. Data on byproducts from other advanced coal technologies and on reuse opportunities are drawn from other sources (citations following Chapter 3). Field results from the 5 test cases examined under this project, together with results from other ongoing research, provide a basis for predictive modeling of long-term performance of some advanced coal byproducts on exposure to ambient environment. This manual is intended to provide a reference database and development plan for designing, permitting, and operating facilities where advanced coal technology byproducts are managed.