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Sample records for advanced transportation institute

  1. Transportation Institutional Plan

    SciTech Connect

    Not Available

    1986-08-01

    This Institutional Plan is divided into three chapters. Chapter 1 provides background information, discusses the purposes of the Plan and the policy guidance for establishing the transportation system, and describes the projected system and the plans for its integrated development. Chapter 2 discusses the major participants who must interact to build the system. Chapter 3 suggests mechanisms for interaction that will foster wide participation in program planning and implementation and provides a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. Also included in this Plan are four appendices. Of particular importance is Appendix A, which includes detailed discussion of specific transportation issues. Appendices B, C, and D provide supporting material to assist the reader in understanding the roles of the involved institutions.

  2. Draft Transportation Institutional Plan

    SciTech Connect

    Not Available

    1985-09-01

    The Department of Energy recognizes that the success of its program to develop and implement a national system for nuclear waste management and disposal depends on broad-based public understanding and acceptance. While each program element has its particular sensitivity, the transportation of the waste may potentially affect the greatest number of people, and accordingly is highly visible and potentially issue-laden. Therefore, the Office of Civilian Radioactive Waste Management has developed this Transportation Institutional Plan to lay the foundation for interaction among all interested parties for the purpose of identifying and resolving issues of concern. The Plan is divided into four chapters. Chapter 1 provides bachground information and discusses the purpose of the Plan and the policy guidance for establishing the transportation system. Chapter 2 introduces the major participants who must interact to build both the system itself and the consensus philosophy that is essential for effective operations. Chapter 3 suggests mechanisms for interaction that will ensure wide participation in program planning and implementation. And, finally, Chapter 4 suggests a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. The Plan's appendices provide supporting material to assist the reader in understanding the roles of the involved institutions. 4 figs., 1 tab.

  3. Engagement and Institutional Advancement

    ERIC Educational Resources Information Center

    Weerts, David; Hudson, Elizabeth

    2009-01-01

    Research suggests that institutional commitment to community engagement can be understood by examining levels of student, faculty, and community involvement in engagement; organizational structure, rewards, and campus publications supporting engagement; and compatibility of an institution's mission with this work (Holland, 1997). Underlying all of…

  4. Advanced space transportation systems

    NASA Technical Reports Server (NTRS)

    Disher, J. H.; Hethcoat, J. P.; Page, M. A.

    1981-01-01

    Projected growth in space transportation capabilities beyond the initial Space Shuttle is discussed in terms of earth-to-low-orbit launch vehicles as well as transportation beyond low orbit (orbit transfer vehicles). Growth versions of the Shuttle and heavy-lift derivatives of the Shuttle are shown conceptually. More advanced launch vehicle concepts are also shown, based on rocket propulsion or combinations of rocket and air-breathing propulsion. Orbit transfer vehicle concepts for personnel transport and for cargo transport are discussed, including chemical rocket as well as electric propulsion. Finally, target levels of capability and efficiencies for later time periods are discussed and compared with the prospective vehicle concepts mentioned earlier.

  5. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Len Volk; Mark Pickell; Evren Ozbayoglu; Barkim Demirdal; Paco Vieira; Affonso Lourenco

    1999-10-15

    This report includes a review of the progress made in ACTF Flow Loop development and research during 90 days pre-award period (May 15-July 14, 1999) and the following three months after the project approval date (July15-October 15, 1999) The report presents information on the following specific subjects; (a) Progress in Advanced Cuttings Transport Facility design and development, (b) Progress report on the research project ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress report on the research project ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress report on the research project ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress report on the research project ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Progress report on the instrumentation tasks (Tasks 11 and 12) (g) Activities towards technology transfer and developing contacts with oil and service company members.

  6. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Lei Zhou

    2000-01-30

    This is the second quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between Oct 1, 2000 and December 31, 2000. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 2: Addition of a foam generation and breaker system), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (d) Research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (e) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (h) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members. The tasks Completed During This Quarter are Task 7 and Task 8.

  7. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Evren Ozbayoglu; Lei Zhou

    2002-04-30

    This is the third quarterly progress report for Year 3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between Jan. 1, 2002 and Mar. 31, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b); (f) Development of a Safety program for the ACTS Flow Loop, progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S); and (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  8. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2003-01-30

    This is the second quarterly progress report for Year-4 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between October 1, 2002 and December 30, 2002. This report presents a review of progress on the following specific tasks. (a) Design and development of an Advanced Cuttings Transport Facility Task 3: Addition of a Cuttings Injection/Separation System, Task 4: Addition of a Pipe Rotation System. (b) New research project (Task 9b): ''Development of a Foam Generator/Viscometer for Elevated Pressure and Elevated Temperature (EPET) Conditions''. (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions''. (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b). (f) New Research project (Task 13): ''Study of Cuttings Transport with Foam under Elevated Pressure and Temperature Conditions''. (g) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (h) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  9. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Affonso Lourenco; Evren Ozbayoglu; Lei Zhou

    2002-01-30

    This is the second quarterly progress report for Year 3 of the ACTS project. It includes a review of progress made in: (1) Flow Loop development and (2) research tasks during the period of time between Oct 1, 2001 and Dec. 31, 2001. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Collection System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  10. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Evren Ozbayoglu; Lei Zhou

    2002-07-30

    This is the fourth quarterly progress report for Year-3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between April 1, 2002 and June 30, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)''; (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions''; (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions''; (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b); (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S); (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  11. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira

    2000-10-30

    This is the first quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between July 14, 2000 and September 30, 2000. This report presents information on the following specific tasks: (a) Progress in Advanced Cuttings Transport Facility design and development (Task 2), (b) Progress on research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress on research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress on research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress on research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Initiate research on project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Progress on instrumentation tasks to measure: Cuttings concentration and distribution (Tasks 11), and Foam properties (Task 12), (h) Initiate a comprehensive safety review of all flow-loop components and operational procedures. Since the previous Task 1 has been completed, we will now designate this new task as: (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  12. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk, Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2002-10-30

    This is the first quarterly progress report for Year-4 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between July 1, 2002 and Sept. 30, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility Task 3: Addition of a Cuttings Injection/Separation System, Task 4: Addition of a Pipe Rotation System, (b) New Research project (Task 9b): ''Development of a Foam Generator/Viscometer for Elevated Pressure and Elevated Temperature (EPET) Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings (Task 12), Viscosity of Foam under EPET (Task 9b). (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  13. Theoretical Advanced Study Institute: 2014

    SciTech Connect

    DeGrand, Thomas

    2016-08-17

    The Theoretical Advanced Study Institute (TASI) was held at the University of Colorado, Boulder, during June 2-27, 2014. The topic was "Journeys through the Precision Frontier: Amplitudes for Colliders." The organizers were Professors Lance Dixon (SLAC) and Frank Petriello (Northwestern and Argonne). There were fifty-one students. Nineteen lecturers gave sixty seventy-five minute lectures. A Proceedings was published. This TASI was unique for its large emphasis on methods for calculating amplitudes. This was embedded in a program describing recent theoretical and phenomenological developments in particle physics. Topics included introductions to the Standard Model, to QCD (both in a collider context and on the lattice), effective field theories, Higgs physics, neutrino interactions, an introduction to experimental techniques, and cosmology.

  14. NASA Institute for Advanced Concepts

    NASA Technical Reports Server (NTRS)

    Cassanova, Robert A.

    1999-01-01

    The purpose of NASA Institute for Advanced Concepts (NIAC) is to provide an independent, open forum for the external analysis and definition of space and aeronautics advanced concepts to complement the advanced concepts activities conducted within the NASA Enterprises. The NIAC will issue Calls for Proposals during each year of operation and will select revolutionary advanced concepts for grant or contract awards through a peer review process. Final selection of awards will be with the concurrence of NASA's Chief Technologist. The operation of the NIAC is reviewed biannually by the NIAC Science, Exploration and Technology Council (NSETC) whose members are drawn from the senior levels of industry and universities. The process of defining the technical scope of the initial Call for Proposals was begun with the NIAC "Grand Challenges" workshop conducted on May 21-22, 1998 in Columbia, Maryland. These "Grand Challenges" resulting from this workshop became the essence of the technical scope for the first Phase I Call for Proposals which was released on June 19, 1998 with a due date of July 31, 1998. The first Phase I Call for Proposals attracted 119 proposals. After a thorough peer review, prioritization by NIAC and technical concurrence by NASA, sixteen subgrants were awarded. The second Phase I Call for Proposals was released on November 23, 1998 with a due date of January 31, 1999. Sixty-three (63) proposals were received in response to this Call. On December 2-3, 1998, the NSETC met to review the progress and future plans of the NIAC. The next NSETC meeting is scheduled for August 5-6, 1999. The first Phase II Call for Proposals was released to the current Phase I grantees on February 3,1999 with a due date of May 31, 1999. Plans for the second year of the contract include a continuation of the sequence of Phase I and Phase II Calls for Proposals and hosting the first NIAC Annual Meeting and USRA/NIAC Technical Symposium in NASA HQ.

  15. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Stefan Miska; Troy Reed; Ergun Kuru

    2004-09-30

    The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimization of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured data. As a

  16. Advanced space transportation technologies

    NASA Technical Reports Server (NTRS)

    Raj, Rishi S.

    1989-01-01

    A wide range of propulsion technologies for space transportation are discussed in the literature. It is clear from the literature review that a single propulsion technology cannot satisfy the many mission needs in space. Many of the technologies tested, proposed, or in experimental stages relate to: chemical and nuclear fuel; radiative and corpuscular external energy source; tethers; cannons; and electromagnetic acceleration. The scope and limitation of these technologies is well tabulated in the literature. Prior experience has shown that an extensive amount of fuel needs to be carried along for the return mission. This requirement puts additional constraints on the lift off rocket technology and limits the payload capacity. Consider the possibility of refueling in space. If the return fuel supply is guaranteed, it will not only be possible to lift off more payload but also to provide security and safety of the mission. Exploration to deep space where solar sails and thermal effects fade would also be possible. Refueling would also facilitate travel on the planet of exploration. This aspect of space transportation prompts the present investigation. The particle emissions from the Sun's corona will be collected under three different conditions: in space closer to the Sun, in the Van Allen Belts; and on the Moon. It is proposed to convert the particle state into gaseous, liquid, or solid state and store it for refueling space vehicles. These facilities may be called space pump stations and the fuel collected as space fuel. Preliminary estimates of fuel collection at all three sites will be made. Future work will continue towards advancing the art of collection rate and design schemes for pumping stations.

  17. Partnering with Families through Institutional Advancement.

    ERIC Educational Resources Information Center

    McInnis, Dion

    2001-01-01

    Because of limited resources and rising populations, more intentional relationships among university departments are needed to achieve common goals, especially in parent programming. Article focuses on novel partnering opportunities for student affairs and institutional advancement departments. (GCP)

  18. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Neelima Godugu

    2000-07-30

    ACTS flow loop is now operational under elevated pressure and temperature. Currently, experiments with synthetic based drilling fluids under pressure and temperature are being conducted. Based on the analysis of Fann 70 data, empirical correlations defining the shear stress as a function of temperature, pressure and the shear rate have been developed for Petrobras synthetic drilling fluids. PVT equipment has been modified for testing Synthetic oil base drilling fluids. PVT tests with Petrobras Synthetic base mud have been conducted and results are being analyzed Foam flow experiments have been conducted and the analysis of the data has been carried out to characterize the rheology of the foam. Comparison of pressure loss prediction from the available foam hydraulic models and the test results has been made. Cuttings transport experiments in horizontal annulus section have been conducted using air, water and cuttings. Currently, cuttings transport tests in inclined test section are being conducted. Foam PVT analysis tests have been conducted. Foam stability experiments have also been conducted. Effects of salt and oil concentration on the foam stability have been investigated. Design of ACTS flow loop modification for foam and aerated mud flow has been completed. A flow loop operation procedure for conducting foam flow experiments under EPET conditions has been prepared Design of the lab-scale flow loop for dynamic foam characterization and cuttings monitoring instrumentation tests has been completed. The construction of the test loop is underway. As part of the technology transport efforts, Advisory Board Meeting with ACTS-JIP industry members has been organized on May 13, 2000.

  19. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mengjiao Yu; Ramadan Ahmed; Mark Pickell; Len Volk; Lei Zhou; Zhu Chen; Aimee Washington; Crystal Redden

    2003-09-30

    The Quarter began with installing the new drill pipe, hooking up the new hydraulic power unit, completing the pipe rotation system (Task 4 has been completed), and making the SWACO choke operational. Detailed design and procurement work is proceeding on a system to elevate the drill-string section. The prototype Foam Generator Cell has been completed by Temco and delivered. Work is currently underway to calibrate the system. Literature review and preliminary model development for cuttings transportation with polymer foam under EPET conditions are in progress. Preparations for preliminary cuttings transport experiments with polymer foam have been completed. Two nuclear densitometers were re-calibrated. Drill pipe rotation system was tested up to 250 RPM. Water flow tests were conducted while rotating the drill pipe up to 100 RPM. The accuracy of weight measurements for cuttings in the annulus was evaluated. Additional modifications of the cuttings collection system are being considered in order to obtain the desired accurate measurement of cuttings weight in the annular test section. Cutting transport experiments with aerated fluids are being conducted at EPET, and analyses of the collected data are in progress. The printed circuit board is functioning with acceptable noise level to measure cuttings concentration at static condition using ultrasonic method. We were able to conduct several tests using a standard low pass filter to eliminate high frequency noise. We tested to verify that we can distinguish between different depths of sand in a static bed of sand. We tested with water, air and a mix of the two mediums. Major modifications to the DTF have almost been completed. A stop-flow cell is being designed for the DTF, the ACTF and Foam Generator/Viscometer which will allow us to capture bubble images without the need for ultra fast shutter speeds or microsecond flash system.

  20. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2003-07-30

    This Quarter has been divided between running experiments and the installation of the drill-pipe rotation system. In addition, valves and piping were relocated, and three viewports were installed. Detailed design work is proceeding on a system to elevate the drill-string section. Design of the first prototype version of a Foam Generator has been finalized, and fabrication is underway. This will be used to determine the relationship between surface roughness and ''slip'' of foams at solid boundaries. Additional cups and rotors are being machined with different surface roughness. Some experiments on cuttings transport with aerated fluids have been conducted at EPET. Theoretical modeling of cuttings transport with aerated fluids is proceeding. The development of theoretical models to predict frictional pressure losses of flowing foam is in progress. The new board design for instrumentation to measure cuttings concentration is now functioning with an acceptable noise level. The ultrasonic sensors are stable up to 190 F. Static tests with sand in an annulus indicate that the system is able to distinguish between different sand concentrations. Viscometer tests with foam, generated by the Dynamic Test Facility (DTF), are continuing.

  1. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2003-04-30

    Experiments on the flow loop are continuing. Improvements to the software for data acquisition are being made as additional experience with three-phase flow is gained. Modifications are being made to the Cuttings Injection System in order to improve control and the precision of cuttings injection. The design details for a drill-pipe Rotation System have been completed. A US Patent was filed on October 28, 2002 for a new design for an instrument that can generate a variety of foams under elevated pressures and temperatures and then transfer the test foam to a viscometer for measurements of viscosity. Theoretical analyses of cuttings transport phenomena based on a layered model is under development. Calibrations of two nuclear densitometers have been completed. Baseline tests have been run to determine wall roughness in the 4 different tests sections (i.e. 2-in, 3-in, 4-in pipes and 5.76-in by 3.5-in annulus) of the flow loop. Tests have also been conducted with aerated fluids at EPET conditions. Preliminary experiments on the two candidate aqueous foam formulations were conducted which included rheological tests of the base fluid and foam stability reports. These were conducted after acceptance of the proposal on the Study of Cuttings Transport with Foam Under Elevated Pressure and Elevated Temperature Conditions. Preparation of a test matrix for cuttings-transport experiments with foam in the ACTF is also under way. A controller for instrumentation to measure cuttings concentration and distribution has been designed that can control four transceivers at a time. A prototype of the control circuit board was built and tested. Tests showed that there was a problem with radiated noise. AN improved circuit board was designed and sent to an external expert to verify the new design. The new board is being fabricated and will first be tested with static water and gravel in an annulus at elevated temperatures. A series of viscometer tests to measure foam properties have

  2. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Stefan Miska; Nicholas Takach; Kaveh Ashenayi

    2004-01-31

    Final design of the mast was completed (Task 5). The mast is consisting of two welded plate girders, set next to each other, and spaced 14-inches apart. Fabrication of the boom will be completed in two parts solely for ease of transportation. The end pivot connection will be made through a single 2-inch diameter x 4 feet-8 inch long 316 SS bar. During installation, hard piping make-ups using Chiksan joints will connect the annular section and 4-inch return line to allow full movement of the mast from horizontal to vertical. Additionally, flexible hoses and piping will be installed to isolate both towers from piping loads and allow recycling operations respectively. Calibration of the prototype Foam Generator Cell has been completed and experiments are now being conducted. We were able to generate up to 95% quality foam. Work is currently underway to attach the Thermo-Haake RS300 viscometer and install a view port with a microscope to measure foam bubble size and bubble size distribution. Foam rheology tests (Task 13) were carried out to evaluate the rheological properties of the proposed foam formulation. After successful completion of the first foam test, two sets of rheological tests were conducted at different foam flow rates while keeping other parameters constant (100 psig, 70F, 80% quality). The results from these tests are generally in agreement with the previous foam tests done previously during Task 9. However, an unanticipated observation during these tests was that in both cases, the frictional pressure drop in 2 inch pipe was lower than that in the 3 inch and 4 inch pipes. We also conducted the first foam cuttings transport test during this quarter. Experiments on aerated fluids without cuttings have been completed in ACTF (Task 10). Gas and liquid were injected at different flow rates. Two different sets of experiments were carried out, where the only difference was the temperature. Another set of tests was performed, which covered a wide range of

  3. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Stefan Miska; Nicholas Takach; Kaveh Ashenayi

    2004-07-31

    We have tested the loop elevation system. We raised the mast to approximately 25 to 30 degrees from horizontal. All went well. However, while lowering the mast, it moved laterally a couple of degrees. Upon visual inspection, severe spalling of the concrete on the face of the support pillar, and deformation of the steel support structure was observed. At this time, the facility is ready for testing in the horizontal position. A new air compressor has been received and set in place for the ACTS test loop. A new laboratory has been built near the ACTS test loop Roughened cups and rotors for the viscometer (RS300) were obtained. Rheologies of aqueous foams were measured using three different cup-rotor assemblies that have different surface roughness. The relationship between surface roughness and foam rheology was investigated. Re-calibration of nuclear densitometers has been finished. The re-calibration was also performed with 1% surfactant foam. A new cuttings injection system was installed at the bottom of the injection tower. It replaced the previous injection auger. A mechanistic model for cuttings transport with aerated mud has been developed. Cuttings transport mechanisms with aerated water at various conditions were experimentally investigated. A total of 39 tests were performed. Comparisons between the model predictions and experimental measurements show a satisfactory agreement. Results from the ultrasonic monitoring system indicated that we could distinguish between different sand levels. We also have devised ways to achieve consistency of performance by securing the sensors in the caps in exactly the same manner as long as the sensors are not removed from the caps. A preliminary test was conducted on the main flow loop at 100 gpm flow rate and 20 lb/min cuttings injection rate. The measured bed thickness using the ultrasonic method showed a satisfactory agreement with nuclear densitometer readings. Thirty different data points were collected after the test

  4. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Len Volk; Mark Pickell; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Neelima Godugu; Sri Suresh Kumar Thiroveedhula

    2000-04-30

    ACTS flow loop is now operational under elevated pressure and temperature. Currently, experiments with water under pressure and temperature are being conducted. Based on the analysis of Fann 70 data, empirical correlations defining the shear stress as a function of temperature, pressure and the shear rate have been developed for Petrobras synthetic drilling fluids. PVT equipment has been modified for testing Synthetic drilling fluids. Initial calibration tests have been conducted by using water. Currently, the base oil of the Petrobras synthetic drilling fluid is being tested. Foam flow experiments have been conducted. Currently, more experiments are being conducted while data are being analyzed to characterize the rheology of the foam. Cuttings transport experiments have been conducted using air, water and cuttings. Preliminary results have shown that it may not be possible to avoid cuttings bed deposition under any practical combination of air and water flow rates. Foam stability analyses have been conducted. Effects of salt and oil concentration on the foam stability have been investigated. A software for controlling the data sampling and data storage during cuttings monitoring process have been developed.

  5. Leveraging Higher Education Consortia for Institutional Advancement

    ERIC Educational Resources Information Center

    Burley, Diana; Gnam, Cathy; Newman, Robin; Straker, Howard; Babies, Tanika

    2012-01-01

    Purpose: The purpose of this paper is to explore conceptually the role of higher education consortia in facilitating the operational advancement of member institutions, and in enabling their development as learning organizations in a changing and competitive higher education environment. Design/methodology/approach: This article synthesizes the…

  6. Advanced Transport Operating Systems Program

    NASA Technical Reports Server (NTRS)

    White, John J.

    1990-01-01

    NASA-Langley's Advanced Transport Operating Systems Program employs a heavily instrumented, B 737-100 as its Transport Systems Research Vehicle (TRSV). The TRSV has been used during the demonstration trials of the Time Reference Scanning Beam Microwave Landing System (TRSB MLS), the '4D flight-management' concept, ATC data links, and airborne windshear sensors. The credibility obtainable from successful flight test experiments is often a critical factor in the granting of substantial commitments for commercial implementation by the FAA and industry. In the case of the TRSB MLS, flight test demonstrations were decisive to its selection as the standard landing system by the ICAO.

  7. Advanced Nanostructures for Two-Phase Fluid and Thermal Transport

    DTIC Science & Technology

    2014-08-07

    AFRL-OSR-VA-TR-2014-0183 (YIP 11) Advanced Nanostructures for Two-Phase Fluid and Thermal Transport Evelyn Wang MASSACHUSETTS INSTITUTE OF TECHNOLOGY...Advanced Nanostructures for Two-Phase Fluid and Thermal Transport AFOSR Grant FA9550-11-1-0059 Final Report Evelyn N. Wang Associate Professor...heated channel wall. Small fluctuations in the measured heater surface temperature (± 3-8 °C) indicated increased flow stability, and the heat transfer

  8. Joint Institute for Advancement of Flight Sciences

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The Aeroacoustics Research Program is an integral part of the Joint Institute for Advancement of Flight Sciences at The George Washington University. It is affiliated with many civil, mechanical, and environmental engineering courses, particularly those that stress theory and numerical or other analytic methods in engineering. This report lists the courses presented, the names of graduate research assistants, and bibliographic information regarding publications and presentations. Three graduate degrees were awarded and the abstracts of each dissertation is included. The dissertations were as follows: "A Numerical Investigation of Thermoacoustic Oscillations", which discusses advances in the study of acoustic phenomena through the use of computational aeroacoustics. "Computation of Vortex Shedding and Radiated Sound for a Circular Cylinder: Subcritical to Transcritical Reynolds Numbers", which discusses predicting tonal noise generated by vortex shedding from a circular cylinder. And finally, "The Radiated Field Generated by a Monopole Source in a Short, Rigid, Rectangular Duct", which develops a method for modeling the acoustic field generated by a monopole source placed in a moving rectangular duct.

  9. Research Institute for Advanced Computer Science

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2000-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center. It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. Ames has been designated NASA's Center of Excellence in Information Technology. In this capacity, Ames is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA Ames and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth; (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking. Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to a

  10. Faculty Development for Institutional Change: Lessons from an Advance Project

    ERIC Educational Resources Information Center

    Laursen, Sandra; Rocque, Bill

    2009-01-01

    The ADVANCE Institutional Transformation projects are remarkably diverse in their theories of action and choice of strategies. However, faculty development plays a role in many, and it was the central change strategy chosen by Leadership Education for Advancement and Promotion (LEAP), the 2002-2008 ADVANCE project at the University of Colorado at…

  11. Advanced technology for future regional transport aircraft

    NASA Technical Reports Server (NTRS)

    Williams, L. J.

    1982-01-01

    In connection with a request for a report coming from a U.S. Senate committee, NASA formed a Small Transport Aircraft Technology (STAT) team in 1978. STAT was to obtain information concerning the technical improvements in commuter aircraft that would likely increase their public acceptance. Another area of study was related to questions regarding the help which could be provided by NASA's aeronautical research and development program to commuter aircraft manufacturers with respect to the solution of technical problems. Attention is given to commuter airline growth, current commuter/region aircraft and new aircraft in development, prospects for advanced technology commuter/regional transports, and potential benefits of advanced technology. A list is provided of a number of particular advances appropriate to small transport aircraft, taking into account small gas turbine engine component technology, propeller technology, three-dimensional wing-design technology, airframe aerodynamics/propulsion integration, and composite structure materials.

  12. Studies of advanced transport aircraft

    NASA Technical Reports Server (NTRS)

    Nagel, A. L.

    1978-01-01

    Concepts for possible future airplanes are studied that include all-wing distributed-load airplanes, multi-body airplanes, a long-range laminar flow control airplane, a nuclear powered airplane designed for towing conventionally powered airplanes during long range cruise, and an aerial transportation system comprised of continuously flying liner airplanes operated in conjunction with short range feeder airplanes. Results indicate that each of these concepts has the potential for important performance and economic advantages, provided certain suggested research tasks are successfully accomplished. Indicated research areas include all-wing airplane aerodynamics, aerial rendezvous, nuclear aircraft engines, air-cushion landing systems, and laminar flow control, as well as the basic research discipline areas of aerodynamics, structures, propulsion, avionics, and computer applications.

  13. Studies of advanced transport aircraft

    NASA Technical Reports Server (NTRS)

    Nagel, A. L.

    1978-01-01

    Several concepts for possible future airplanes, including all-wing distributed-load airplanes, multibody airplanes, a long-range laminar flow control airplane, a nuclear-powered airplane designed for towing conventionally powered airplanes during long-range cruise, and an aerial transportation system comprised of continuously flying liner airplanes operated in conjunction with short-range feeder airplanes are described. Performance and economic advantages of each concept are indicated. Further research is recommended in the following areas: all-wing airplane aerodynamics, aerial rendezvous, nuclear aircraft engines, air-cushion landing systems, and laminar flow control, as well as the basic research discipline areas of aerodynamics, structures, propulsion, avionics, and computer applications.

  14. Outlook for advanced concepts in transport aircraft

    NASA Technical Reports Server (NTRS)

    Conner, D. W.

    1980-01-01

    Air transportation demand trends, air transportation system goals, and air transportation system trends well into the 21st century were examined in detail. The outlook is for continued growth in both air passenger travel and air freight movements. The present system, with some improvements, is expected to continue to the turn of the century and to utilize technologically upgraded, derivative versions of today's aircraft, plus possibly some new aircraft for supersonic long haul, short haul, and high density commuter service. Severe constraints of the system, expected by early in the 21st century, should lead to innovations at the airport, away from the airport, and in the air. The innovations are illustrated by descriptions of three candidate systems involving advanced aircraft concepts. Advanced technologies and vehicles expected to impact the airport are illustrated by descriptions of laminar flow control aircraft, very large air freighters and cryogenically fueled transports.

  15. A review of advanced turboprop transport aircraft

    NASA Astrophysics Data System (ADS)

    Lange, Roy H.

    The application of advanced technologies shows the potential for significant improvement in the fuel efficiency and operating costs of future transport aircraft envisioned for operation in the 1990s time period. One of the more promising advanced technologies is embodied in an advanced turboprop concept originated by Hamilton Standard and NASA and known as the propfan. The propfan concept features a highly loaded multibladed, variable pitch propeller geared to a high pressure ratio gas turbine engine. The blades have high sweepback and advanced airfoil sections to achieve 80 percent propulsive efficiency at M=0.80 cruise speed. Aircraft system studies have shown improvements in fuel efficiency of 15-20 percent for propfan advanced transport aircraft as compared to equivalent turbofan transports. Beginning with the Lockheed C-130 and Electra turboprop aircraft, this paper presents an overview of the evolution of propfan aircraft design concepts and system studies. These system studies include possible civil and military transport applications and data on the performance, community and far-field noise characteristics and operating costs of propfan aircraft design concepts. NASA Aircraft Energy Efficiency (ACEE) program propfan projects with industry are reviewed with respect to system studies of propfan aircraft and recommended flight development programs.

  16. Growing a Development Program into Institutional Advancement.

    ERIC Educational Resources Information Center

    Connell, Joseph

    2003-01-01

    Discusses how Moreau Catholic High School has had a 290% growth in a 3-4 year period. Author attributes this to (1) insightful board of trustees; (2) fundraising achieved through friendship; (3) providing individual opportunities for advancing the school; and (4) focusing on principles of Christian stewardship, philanthropy, collaboration, and…

  17. NSF ADVANCE: Institutional Transformation to Achieve Faculty Diversity

    NASA Astrophysics Data System (ADS)

    Anthony, E. Y.

    2004-12-01

    The NSF ADVANCE initiative is designed to enhance gender equity in academic science and engineering faculty. One of its components - Institutional Transformation - has the goal of establishing strategies and policies that will revolutionize institutional climate so that diverse faculty flourish. The University of Texas at El Paso is one of 19 institutions to currently hold a 5-year grant under the Institutional Transformation program. This poster presentation highlights practices from the participating institutions. Two general aspects of the program are: 1) co-principal investigators are a blend of administrators and active researchers. This blend ensures a bottom-up, top-down approach to presenting gender equity to faculty. 2) Many of the investigators have diversity as their research focus, which is intended to result in rigorous, peer-reviewed dissemination of institutional results. Specific effors for all institutions relate to recruitment, retention, and advancement of female faculty and, by establishing equitable conditions, to improvement of the workplace for all faculty. To aid recruitment, institutions have committed faculty involved in the search process, including training of search committees in diversity strategies and interaction with candidates. A close working relationship with the campus EO officer is essential. Retention strategies center on mentoring, monetary support for research, and policy implementation. Policies focus on work-family balance. Advancement of females to important administrative and non-administrative leadership roles is the third focus. Workshops and seminars on leadership skills are common in the various institutions. Finally, a central theme of the program is that, in addition to specific strategies, institutions must articulate diversity as a core value and reflect on the means to actualize this value. More information on the NSF ADVANCE program, including links to the Institutional Transformation grantees, may be found on

  18. Joint Institute for Advancement of Flight Sciences

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The program objectives were defined in the original proposal entitled "Program of Research in Flight Dynamics in the JIAFS at NASA Langley Research Center" which was originated March 20, 1975, and in yearly renewals of the research program dated December 1, 1979 to December 1, 1998. The program included three major topics: 1) Improvement of existing methods and development of new methods for flight and wind tunnel data analysis based on system identification methodology. 2) Application of these methods to flight and wind tunnel data obtained from advanced aircraft. 3) Modeling and control of aircraft, space structures and spacecraft. The principal investigator of the program was Dr. Vladislav Klein, Professor at The George Washington University, Washington, D.C.. Thirty-seven Graduate Research Scholar Assistants, two of them doctoral students, also participated in the program. The results of the research conducted during nineteen years of the total co-operative period were published in 23 NASA technical reports, 2 D.Sc. Dissertations, 14 M.S. Theses and 33 papers. The list of these publications is included. The results were also reported in more than 30 seminar lectures presented at various research establishments world-wide. For contributions to the research supported by the co-operative agreement, three NASA Awards were received: 1) NASA LARC Group Achievement Award, May 30, 1990, to Dr. V. Klein as a member of the X-29 Drop Model Team. 2) NASA Medal for Exceptional Engineering Achievement, March 27, 1992, to Dr. V. Klein for innovative contributions in the development of advanced techniques and computer programs in the field of system identification. 3) NASA LaRC Team Excellence Award, May 7, 1994, to Dr. V. Klein as a member of the X-31 Drop Model Team.

  19. NATO Advanced Study Institute on Spectroscopy

    NASA Technical Reports Server (NTRS)

    DiBartolo, Baldassare; Barnes, James (Technical Monitor)

    2001-01-01

    This booklet presents an account of the course 'Spectroscopy of Systems with Spatially Confined Structures' held in Erice-Sicily, Italy, from June 15 to June 30, 2001. This meeting was organized by the International School of Atomic and Molecular Spectroscopy of the 'Ettore Majorana' Centre for Scientific Culture. The purpose of this course was to present and discuss nanometer-scale physics, a rapidly progressing field. The top-down approach of semiconductor technology will soon meet the scales of the bottom-up approaches of supramolecular chemistry and of spatially localized excitations in ionic crystals. This course dealt with the fabrication, measurement and understanding of the relevant structures and brought together the scientific communities responsible for these development. The advances in this area of physics have already let to applications in optoelectronics and will likely lead to many more. The subjects of the course included spatially resolved structures such as quantum wells, quantum wires and quantum dots, single atoms and molecules, clusters, fractal systems, and the development of related techniques like near-field spectroscopy and confocal microscopy to study such systems.

  20. Propulsion technology for an advanced subsonic transport

    NASA Technical Reports Server (NTRS)

    Beheim, M. A.; Antl, R. J.; Povolny, J. H.

    1972-01-01

    Engine design studies for future subsonic commercial transport aircraft were conducted in parallel with airframe studies. These studies surveyed a broad distribution of design variables, including aircraft configuration, payload, range, and speed, with particular emphasis on reducing noise and exhaust emissions without severe economic and performance penalties. The results indicated that an engine for an advanced transport would be similar to the currently emerging turbofan engines. Application of current technology in the areas of noise suppression and combustors imposed severe performance and economic penalties.

  1. Advanced control technology and its potential for future transport aircraft

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.

  2. Individuals and Institutions : How to Advance Women in Science

    NASA Astrophysics Data System (ADS)

    Valian, Virginia

    2015-01-01

    The inception of the NSF ADVANCE program marked a change in NSF's efforts to improve the advancement of women in the sciences. Previous efforts had focused on providing women with funding to pursue their research. ADVANCE focuses on changing the institutions in which women do their research. Evidence of ADVANCE's successes can be seen both in the careers of individual women and in hiring and retention figures at the institutions that received funding. In Part 1, I will review interventions that help women to succeed, with a focus on the Sponsorship Program and the Workshop Series for Junior Faculty that the Gender Equity Project at Hunter College developed. In Part 2, I will review successes in changing hiring practices, with a focus on ADVANCE programs from the University of Michigan and the University of Wisconsin. In Part 3, I will analyze the costs and benefits of the two types of intervention, including the long time course of institutional change, the helpful or hurtful role that leaders can play, the need for intervention at the departmental level, and the potential for individuals to change institutions.

  3. Advanced Terrain Displays for Transport Category Aircraft.

    DTIC Science & Technology

    1992-02-01

    Map Displays, Terrain Displays, DOCUMENT IS AVAILABLE TO THE PUBLIC THROUGH Pilo t Performance, THE NATIONAL TECHNICAL INFORMATION SERVICE , Cockp •t...DOT/FAA/RD-9214 Advanced Terran Wigays DOT-VNTSC-FAA-92-4 frTaaotCta Research and Development Servic fo rasor atgr Washington, DC 20591 Aircraft...U.S. Department of Transportation Final Report Federal Aviation Administration January 1991-Sept. 1991 Research and Development Service Washington, DC

  4. Overview of NASA Advanced Transportation Technologies Program

    NASA Technical Reports Server (NTRS)

    Ashford, Rose; Jacobsen, R. A. (Technical Monitor)

    1998-01-01

    A General Overview of NASA Advanced Transportation Technologies Program is presented. The contents include: 1) Center-TRACON Automation System (CTAS) which provides automation tools to assist air traffic controllers in planning and controlling air traffic arriving into major airports; 2) Surface Movement Advisor (SMA) for expediting and optimizing aircraft operations on the airport surface; and 3) Terminal Area Productivity Program (TAP), which is aimed at improving airport throughput in instrument meteorological conditions to match that attainable in clear weather.

  5. Advanced secondary power system for transport aircraft

    NASA Technical Reports Server (NTRS)

    Hoffman, A. C.; Hansen, I. G.; Beach, R. F.; Plencner, R. M.; Dengler, R. P.; Jefferies, K. S.; Frye, R. J.

    1985-01-01

    A concept for an advanced aircraft power system was identified that uses 20-kHz, 440-V, sin-wave power distribution. This system was integrated with an electrically powered flight control system and with other aircraft systems requiring secondary power. The resulting all-electric secondary power configuration reduced the empty weight of a modern 200-passenger, twin-engine transport by 10 percent and the mission fuel by 9 percent.

  6. Green Propulsion Technologies for Advanced Air Transports

    NASA Technical Reports Server (NTRS)

    Del Rosario, Ruben

    2015-01-01

    Air transportation is critical to U.S. and Global economic vitality. However, energy and climate issues challenge aviations ability to be sustainable in the long term. Aviation must dramatically reduce fuel use and related emissions. Energy costs to U.S. airlines nearly tripled between 1995 and 2011, and continue to be the highest percentage of operating costs. The NASA Advanced Air Transports Technology Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the NASA vision of revolutionary systems and propulsion technologies needed to achieve these challenging goals. Specifically, the primary focus is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe, which are envisioned as being powered by Hybrid Electric Propulsion Systems.

  7. Green Propulsion Technologies for Advanced Air Transports

    NASA Technical Reports Server (NTRS)

    Del Rosario, Ruben

    2015-01-01

    Air transportation is critical to U.S. and Global economic vitality. However, energy and climate issues challenge aviation's ability to be sustainable in the long term. Aviation must dramatically reduce fuel use and related emissions. Energy costs to U.S. airlines nearly tripled between 1995 and 2011, and continue to be the highest percentage of operating costs. The NASA Advanced Air Transports Technology Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the NASA vision of revolutionary systems and propulsion technologies needed to achieve these challenging goals. Specifically, the primary focus is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe.

  8. Institutional Advancement: A Marketing Perspective. Part I: A Proposal.

    ERIC Educational Resources Information Center

    Moriarty, Daniel F.

    Strategies are proposed for the implementation of the marketing concept at Triton College. The report begins by describing the establishment and goals of the Marketing Task Force and goes on to define "institutional advancement," as a positive, progressive response to community educational needs, and "the marketing concept," as suggesting an…

  9. The Advanced Technology Environmental Education Center Summer Fellows Institute.

    ERIC Educational Resources Information Center

    Depken, Diane E.; Zeman, Catherine L.; Lensch, Ellen Kabat; Brown, Edward J.

    2002-01-01

    Describes the background, activities, and outcomes of the Advanced Technology Environmental Education Center (ATEEC) and its Summer Fellows Institutes as a model for disciplinary and cross-disciplinary infusion of environmental science and technology content, curriculum, and methods into the classroom. Presents experiences, themes, and activities…

  10. Methodological advances in imaging intravital axonal transport

    PubMed Central

    Sleigh, James N.; Vagnoni, Alessio; Twelvetrees, Alison E.; Schiavo, Giampietro

    2017-01-01

    Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction. Bi-directional transport in axons is absolutely essential for the functioning and survival of neurons and appears to be negatively impacted by both aging and diseases of the nervous system, such as Alzheimer’s disease and amyotrophic lateral sclerosis. The movement of individual cargoes along axons has been studied in vitro in live neurons and tissue explants for a number of years; however, it is currently unclear as to whether these systems faithfully and consistently replicate the in vivo situation. A number of intravital techniques originally developed for studying diverse biological events have recently been adapted to monitor axonal transport in real-time in a range of live organisms and are providing novel insight into this dynamic process. Here, we highlight these methodological advances in intravital imaging of axonal transport, outlining key strengths and limitations while discussing findings, possible improvements, and outstanding questions. PMID:28344778

  11. Methodological advances in imaging intravital axonal transport.

    PubMed

    Sleigh, James N; Vagnoni, Alessio; Twelvetrees, Alison E; Schiavo, Giampietro

    2017-01-01

    Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction. Bi-directional transport in axons is absolutely essential for the functioning and survival of neurons and appears to be negatively impacted by both aging and diseases of the nervous system, such as Alzheimer's disease and amyotrophic lateral sclerosis. The movement of individual cargoes along axons has been studied in vitro in live neurons and tissue explants for a number of years; however, it is currently unclear as to whether these systems faithfully and consistently replicate the in vivo situation. A number of intravital techniques originally developed for studying diverse biological events have recently been adapted to monitor axonal transport in real-time in a range of live organisms and are providing novel insight into this dynamic process. Here, we highlight these methodological advances in intravital imaging of axonal transport, outlining key strengths and limitations while discussing findings, possible improvements, and outstanding questions.

  12. NASA's Advanced Space Transportation Hypersonic Program

    NASA Technical Reports Server (NTRS)

    Hueter, Uwe; McClinton, Charles; Cook, Stephen (Technical Monitor)

    2002-01-01

    NASA's has established long term goals for access-to-space. NASA's third generation launch systems are to be fully reusable and operational in approximately 25 years. The goals for third generation launch systems are to reduce cost by a factor of 100 and improve safety by a factor of 10,000 over current conditions. The Advanced Space Transportation Program Office (ASTP) at NASA's Marshall Space Flight Center in Huntsville, AL has the agency lead to develop third generation space transportation technologies. The Hypersonics Investment Area, part of ASTP, is developing the third generation launch vehicle technologies in two main areas, propulsion and airframes. The program's major investment is in hypersonic airbreathing propulsion since it offers the greatest potential for meeting the third generation launch vehicles. The program will mature the technologies in three key propulsion areas, scramjets, rocket-based combined cycle and turbine-based combination cycle. Ground and flight propulsion tests are being planned for the propulsion technologies. Airframe technologies will be matured primarily through ground testing. This paper describes NASA's activities in hypersonics. Current programs, accomplishments, future plans and technologies that are being pursued by the Hypersonics Investment Area under the Advanced Space Transportation Program Office will be discussed.

  13. Presidential Leadership in Institutional Advancement: From the Perspective of the President and Vice President of Institutional Advancement

    ERIC Educational Resources Information Center

    Sturgis, Rhonda

    2006-01-01

    Since the establishment of higher education systems in the US the position of college and university president has evolved. In regards to fund-raising this position has changed dramatically with the creation of the vice president of institutional advancement. Over time these two positions have expanded the fund-raising function into a team effort.…

  14. The San Francisco Joint Institutional Transportation Systems Management Program.

    ERIC Educational Resources Information Center

    Fink, Ira; LaPointe, Robert

    1981-01-01

    Transportation systems management (TSM) programs are discussed, particularly the 1977 program of the University of California, San Francisco, which led to traffic reduction and improved vehicle flow. The city's implementation plan for a similar TSM program for 14 educational institutions and hospitals is described. (MLW)

  15. Institutional transformation: An analysis of change initiatives at NSF ADVANCE institutions

    NASA Astrophysics Data System (ADS)

    Plummer, Ellen W.

    The purpose of this study was to examine how institutional culture promoted or impeded the implementation of round one and two NSF ADVANCE initiatives designed to improve academic climates for women in science and engineering. This study was conducted in two phases. In phase one, 35 participants from 18 institutions were interviewed to answer three research questions. Participants identified a policy, process, or program designed to improve academic cultures for women in science and engineering fields. Participants also identified strategies that promoted the implementation of these efforts, and discussed factors that impeded these efforts. In phase two, site visits were conducted at two institutions to answer a fourth research question. How did institutional culture shape the design and implementation of faculty search processes? Policies, processes, and programs were implemented by participants at the institutional, departmental, and individual levels and included family friendly and dual career policies at the institutional level, improved departmental faculty search and climate improvement processes, and mentoring programs and training for department heads at the individual level. Communication and leadership strategies were key to the successful implementation of policies, processes, and programs designed to achieve institutional transformation. Communication strategies involved shaping change messages to reach varied audiences often with the argument that change efforts would improve the climate for everyone not just women faculty members. Administrative and faculty leaders from multiple levels proved important to change efforts. Institutional Transformation Institutional culture shaped initiatives to improve faculty search processes. Faculty leaders in both settings used data to persuade faculty members of the need for change. At one site, data that included national availability information was critical to advancing the change agenda. At the other site

  16. Advanced Civil Transport Simulator Cockpit View

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Advanced Civil Transport Simulator (ACTS) is a futuristic aircraft cockpit simulator designed to provide full-mission capabilities for researching issues that will affect future transport aircraft flight stations and crews. The objective is to heighten the pilots situation awareness through improved information availability and ease of interpretation in order to reduce the possibility of misinterpreted data. The simulators five 13-inch Cathode Ray Tubes are designed to display flight information in a logical easy-to-see format. Two color flat panel Control Display Units with touch sensitive screens provide monitoring and modification of aircraft parameters, flight plans, flight computers, and aircraft position. Three collimated visual display units have been installed to provide out-the-window scenes via the Computer Generated Image system. The major research objectives are to examine needs for transfer of information to and from the flight crew; study the use of advanced controls and displays for all-weather flying; explore ideas for using computers to help the crew in decision making; study visual scanning and reach behavior under different conditions with various levels of automation and flight deck-arrangements.

  17. From "fixing women" to "institutional transformation": An ADVANCE case study

    NASA Astrophysics Data System (ADS)

    Yennello, Sherry; Kaunas, Christine

    2015-12-01

    The United States' position in the global economy requires an influx of women into science, technology, engineering, and mathematics (STEM) fields in order to remain competitive. Despite this, the representation of women in STEM continues to be low. The National Science Foundation's ADVANCE Program addresses this issue by funding projects that aim to increase the representation of women in academic STEM fields through transformation of institutional structures that impede women's progress in academic STEM fields. This paper includes a case study of the Texas A&M University ADVANCE Program.

  18. Institute for Advanced Materials at University of Louisville

    SciTech Connect

    Sunkara, Mahendra; Sumaneskara, Gamini; Starr, Thomas L; Willing, G A; Robert W, Cohn

    2009-10-29

    In this project, a university-wide, academic center has been established entitled Institute for Advanced Materials and Renewable Energy. In this institute, a comprehensive materials characterization facility has been established by co-locating several existing characterization equipment and acquiring several state of the art instrumentation such as field emission transmission electron microscope, scanning electron microscope, high resolution X-ray diffractometer, Particle Size Distribution/Zeta Potential measurement system, and Ultra-microtome for TEM specimen. In addition, a renewable energy conversion and storage research facility was also established by acquiring instrumentation such as UV-Vis absorption spectroscopy, Atomic Layer Deposition reactor, Solar light simulator, oxygen-free glove box, potentiostat/galvanostats and other miscellaneous items. The institute is staffed with three full-time staff members (one senior research technologist, a senior PhD level research scientist and a junior research scientist) to enable proper use of the techniques. About thirty faculty, fifty graduate students and several researchers access the facilities on a routine basis. Several industry R&D organizations (SudChemie, Optical Dynamics and Hexion) utilize the facility. The established Institute for Advanced Materials at UofL has three main objectives: (a) enable a focused research effort leading to the rapid discovery of new materials and processes for advancing alternate energy conversion and storage technologies; (b) enable offering of several laboratory courses on advanced materials science and engineering; and (c) develop university-industry partnerships based on the advanced materials research. The Institute's efforts were guided by an advisory board comprising eminent researchers from outside KY. Initial research efforts were focused on the discovery of new materials and processes for solar cells and Li ion battery electrodes. Initial sets of results helped PIs to

  19. The AC-120: The advanced commercial transport

    NASA Technical Reports Server (NTRS)

    Duran, David; Griffin, Ernest; Mendoza, Saul; Nguyen, Son; Pickett, Tim; Noernberg, Clemm

    1993-01-01

    The main objective of this design was to fulfill a need for a new airplane to replace the aging 100 to 150 passenger, 1500 nautical mile range aircraft such as the Douglas DC9 and Boeing 737-100 airplanes. After researching the future aircraft market, conducting extensive trade studies, and analysis on different configurations, the AC-120 Advanced Commercial Transport final design was achieved. The AC-120's main design features include the incorporation of a three lifting surface configuration which is powered by two turboprop engines. The AC-120 is an economically sensitive aircraft which meets the new FM Stage Three noise requirements, and has lower NO(x) emissions than current turbofan powered airplanes. The AC-120 also improves on its contemporaries in passenger comfort, manufacturing, and operating cost.

  20. NASA's advanced space transportation system launch vehicles

    NASA Technical Reports Server (NTRS)

    Branscome, Darrell R.

    1991-01-01

    Some insight is provided into the advanced transportation planning and systems that will evolve to support long term mission requirements. The general requirements include: launch and lift capacity to low earth orbit (LEO); space based transfer systems for orbital operations between LEO and geosynchronous equatorial orbit (GEO), the Moon, and Mars; and Transfer vehicle systems for long duration deep space probes. These mission requirements are incorporated in the NASA Civil Needs Data Base. To accomplish these mission goals, adequate lift capacity to LEO must be available: to support science and application missions; to provide for construction of the Space Station Freedom; and to support resupply of personnel and supplies for its operations. Growth in lift capacity must be time phased to support an expanding mission model that includes Freedom Station, the Mission to Planet Earth, and an expanded robotic planetary program. The near term increase in cargo lift capacity associated with development of the Shuttle-C is addressed. The joint DOD/NASA Advanced Launch System studies are focused on a longer term new cargo capability that will significantly reduce costs of placing payloads in space.

  1. Laying Plans for Continuing Concerts: The National Institute for the Advancement of Career Education.

    ERIC Educational Resources Information Center

    Feller, Richard J.; And Others

    1982-01-01

    Discusses elements of the National Institute for the Advancement of Career Education: the need for such an institute, areas of concentration (instruction, leadership, development, research), and how interested persons can cooperate in the institute. (CT)

  2. Advanced space transportation systems, BARGOUZIN booster

    NASA Astrophysics Data System (ADS)

    Prampolini, Marco; Louaas, Eric; Prel, Yves; Kostromin, Sergey; Panichkin, Nickolay; Sumin, Yuriy; Osin, Mikhail; Iranzo-Greus, David; Rigault, Michel; Beaurain, André; Couteau, Jean-Noël

    2008-07-01

    In the framework of Advanced Space Transportation Systems Studies sponsored by CNES in 2006, a study called "BARGOUZIN" was performed by a joint team led by ASTRIUM ST and TSNIIMASH. Beyond these leaders, the team comprised MOLNIYA, DASSAULT AVIATION and SNECMA as subcontractors. The "BARGOUZIN" concept is a liquid fuelled fly-back booster (LFBB), mounted on the ARIANE 5 central core stage in place of the current solid rocket booster. The main originality of the concept lies in the fact that the "BARGOUZIN" features a cluster of VULCAIN II engines, similar to the one mounted on the central core stage of ARIANE 5. An astute permutation strategy, between the booster engines and central core engine is expected to lead to significant cost reductions. The following aspects were addressed during the preliminary system study: engine number per booster trade-off/abort scenario analysis, aerodynamic consolidation, engine reliability, ascent controllability, ground interfaces separation sequence analysis, programmatics. These topics will be briefly presented and synthesized in this paper, giving an overview of the credibility of the concept.

  3. Advanced Hydrogen Transport Membrane for Coal Gasification

    SciTech Connect

    Schwartz, Joseph; Porter, Jason; Patki, Neil; Kelley, Madison; Stanislowski, Josh; Tolbert, Scott; Way, J. Douglas; Makuch, David

    2015-12-23

    A pilot-scale hydrogen transport membrane (HTM) separator was built that incorporated 98 membranes that were each 24 inches long. This separator used an advanced design to minimize the impact of concentration polarization and separated over 1000 scfh of hydrogen from a hydrogen-nitrogen feed of 5000 scfh that contained 30% hydrogen. This mixture was chosen because it was representative of the hydrogen concentration expected in coal gasification. When tested with an operating gasifier, the hydrogen concentration was lower and contaminants in the syngas adversely impacted membrane performance. All 98 membranes survived the test, but flux was lower than expected. Improved ceramic substrates were produced that have small surface pores to enable membrane production and large pores in the bulk of the substrate to allow high flux. Pd-Au was chosen as the membrane alloy because of its resistance to sulfur contamination and good flux. Processes were developed to produce a large quantity of long membranes for use in the demonstration test.

  4. The Transporter Classification Database (TCDB): recent advances

    PubMed Central

    Saier, Milton H.; Reddy, Vamsee S.; Tsu, Brian V.; Ahmed, Muhammad Saad; Li, Chun; Moreno-Hagelsieb, Gabriel

    2016-01-01

    The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB. PMID:26546518

  5. Application of advanced technologies to future military transports

    NASA Technical Reports Server (NTRS)

    Clark, Rodney L.; Lange, Roy H.; Wagner, Richard D.

    1990-01-01

    Long range military transport technologies are addressed with emphasis of defining the potential benefits of the hybrid laminar flow control (HLFC) concept currently being flight tested. Results of a 1990's global range transport study are presented showing the expected payoff from application of advanced technologies. Technology forecast for military transports is also presented.

  6. Advanced propulsion for LEO-Moon transport. 3: Transportation model. M.S. Thesis - California Univ.

    NASA Technical Reports Server (NTRS)

    Henley, Mark W.

    1992-01-01

    A simplified computational model of low Earth orbit-Moon transportation system has been developed to provide insight into the benefits of new transportation technologies. A reference transportation infrastructure, based upon near-term technology developments, is used as a departure point for assessing other, more advanced alternatives. Comparison of the benefits of technology application, measured in terms of a mass payback ratio, suggests that several of the advanced technology alternatives could substantially improve the efficiency of low Earth orbit-Moon transportation.

  7. Recent advances in understanding hepatic drug transport

    PubMed Central

    Stieger, Bruno; Hagenbuch, Bruno

    2016-01-01

    Cells need to strictly control their internal milieu, a function which is performed by the plasma membrane. Selective passage of molecules across the plasma membrane is controlled by transport proteins. As the liver is the central organ for drug metabolism, hepatocytes are equipped with numerous drug transporters expressed at the plasma membrane. Drug disposition includes absorption, distribution, metabolism, and elimination of a drug and hence multiple passages of drugs and their metabolites across membranes. Consequently, understanding the exact mechanisms of drug transporters is essential both in drug development and in drug therapy. While many drug transporters are expressed in hepatocytes, and some of them are well characterized, several transporters have only recently been identified as new drug transporters. Novel powerful tools to deorphanize (drug) transporters are being applied and show promising results. Although a large set of tools are available for studying transport in vitro and in isolated cells, tools for studying transport in living organisms, including humans, are evolving now and rely predominantly on imaging techniques, e.g. positron emission tomography. Imaging is an area which, certainly in the near future, will provide important insights into "transporters at work" in vivo. PMID:27781095

  8. [Activities of Research Institute for Advanced Computer Science

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  9. Activities of the Research Institute for Advanced Computer Science

    NASA Technical Reports Server (NTRS)

    Oliger, Joseph

    1994-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

  10. Institutional Advancement Strategies in Hard Times. AAHE-ERIC/Higher Education Research Report No. 2.

    ERIC Educational Resources Information Center

    Richards, Michael D.; Sherratt, Gerald R.

    The historical role of institutional advancement and the specific activities and trends currently affecting it are reviewed, and four strategies for advancement programs are suggested. Institutional advancement includes alumni relations, fund-raising, public relations, internal and external communications, and government relations, and its…

  11. Community College Vice Presidents for Institutional Advancement: Role Expectations, Fundraising Responsibilities, Professional Relationships, and Commitment to the Institution

    ERIC Educational Resources Information Center

    Ciampa, Donna Lynn

    2009-01-01

    This study examined how the role expectations, responsibilities toward fundraising, and professional relationships by the vice president of institutional advancement influenced commitment to the institution. A qualitative analysis was conducted across the mid-Atlantic region by interviewing community college vice presidents of institutional…

  12. Report on the 1966 NDEA Advanced Study Institute in Economics.

    ERIC Educational Resources Information Center

    Reese, Jim E.; Darcy, Robert L.

    This report is one of a series presenting the results of studies of NDEA Title XI and Arts and Humanities Foundation Institute programs and selected institute-associated activities conducted in 1966. During that year, five economics institutes were held. The 175 participants in these institutes were involved in a variety of programs, including one…

  13. [Advances in plant anthocyanin transport mechanism].

    PubMed

    Wang, Lu; Dai, Silan; Jin, Xuehua; Huang, He; Hong, Yan

    2014-06-01

    Anthocyanin biosynthesis is one of the thoroughly studied enzymatic pathways in biology, but little is known about the molecular mechanisms of its final stage: the transport of the anthocyanins into the vacuole. A clear picture of the dynamic trafficking of flavonoids is only now beginning to emerge. So far four different models have been proposed to explain the transport of anthocyanins from biosynthetic sites to the central vacuole, and four types of transporters have been found associated with the transport of anthocyanins: glutathione S-transferase, multidrug resistance-associated protein, multidrug and toxic compound extrusion, bilitranslocase-homologue. The functions of these proteins and related genes have also been studied. Although different models have been proposed, cellular and subcellular information is still lacking for reconciliation of different lines of evidence in various anthocyanin sequestration studies. According to the information available, through sequence analysis, gene expression analysis, subcellular positioning and complementation experiments, the function and location of these transporters can be explored, and the anthocyanin transport mechanism can be better understood.

  14. Advanced methods of structural and trajectory analysis for transport aircraft

    NASA Technical Reports Server (NTRS)

    Ardema, Mark D.

    1995-01-01

    This report summarizes the efforts in two areas: (1) development of advanced methods of structural weight estimation, and (2) development of advanced methods of trajectory optimization. The majority of the effort was spent in the structural weight area. A draft of 'Analytical Fuselage and Wing Weight Estimation of Transport Aircraft', resulting from this research, is included as an appendix.

  15. Chemical Kinetic Modeling of Advanced Transportation Fuels

    SciTech Connect

    PItz, W J; Westbrook, C K; Herbinet, O

    2009-01-20

    Development of detailed chemical kinetic models for advanced petroleum-based and nonpetroleum based fuels is a difficult challenge because of the hundreds to thousands of different components in these fuels and because some of these fuels contain components that have not been considered in the past. It is important to develop detailed chemical kinetic models for these fuels since the models can be put into engine simulation codes used for optimizing engine design for maximum efficiency and minimal pollutant emissions. For example, these chemistry-enabled engine codes can be used to optimize combustion chamber shape and fuel injection timing. They also allow insight into how the composition of advanced petroleum-based and non-petroleum based fuels affect engine performance characteristics. Additionally, chemical kinetic models can be used separately to interpret important in-cylinder experimental data and gain insight into advanced engine combustion processes such as HCCI and lean burn engines. The objectives are: (1) Develop detailed chemical kinetic reaction models for components of advanced petroleum-based and non-petroleum based fuels. These fuels models include components from vegetable-oil-derived biodiesel, oil-sand derived fuel, alcohol fuels and other advanced bio-based and alternative fuels. (2) Develop detailed chemical kinetic reaction models for mixtures of non-petroleum and petroleum-based components to represent real fuels and lead to efficient reduced combustion models needed for engine modeling codes. (3) Characterize the role of fuel composition on efficiency and pollutant emissions from practical automotive engines.

  16. Advanced Resources for Catalysis Science; Recommendations for a National Catalysis Research Institute

    SciTech Connect

    Peden, Charles HF.; Ray, Douglas

    2005-10-05

    Catalysis is one of the most valuable contributors to our economy and historically an area where the United States has enjoyed, but is now losing, international leadership. While other countries are stepping up their work in this area, support for advanced catalysis research and development in the U.S. has diminished. Yet, more than ever, innovative and improved catalyst technologies are imperative for new energy production processes to ease our dependence on imported resources, for new energy-efficient and environmentally benign chemical production processes, and for new emission reduction technologies to minimize the environmental impact of an active and growing economy. Addressing growing concerns about the future direction of U.S. catalysis science, experts from the catalysis community met at a workshop to determine and recommend advanced resources needed to address the grand challenges for catalysis research and development. The workshop's primary conclusion: To recapture our position as the leader in catalysis innovation and practice, and promote crucial breakthroughs, the U.S. must establish one or more well-funded and well-equipped National Catalysis Research Institutes competitively selected, centered in the national laboratories and, by charter, networked to other national laboratories, universities, and industry. The Institute(s) will be the center of a national collaboratory that gives catalysis researchers access to the most advanced techniques available in the scientific enterprise. The importance of catalysis to our energy, economic, and environmental security cannot be overemphasized. Catalysis is a vital part of our core industrial infrastructure, as it is integral to chemical processing and petroleum refining, and is critical to proposed advances needed to secure a sustainable energy future. Advances in catalysis could reduce our need for foreign oil by making better use of domestic carbon resources, for example, allowing cost-effective and zero

  17. The impact of emerging technologies on an advanced supersonic transport

    NASA Technical Reports Server (NTRS)

    Driver, C.; Maglieri, D. J.

    1986-01-01

    The effects of advances in propulsion systems, structure and materials, aerodynamics, and systems on the design and development of supersonic transport aircraft are analyzed. Efficient propulsion systems with variable-cycle engines provide the basis for improved propulsion systems; the propulsion efficienies of supersonic and subsonic engines are compared. Material advances consist of long-life damage-tolerant structures, advanced material development, aeroelastic tailoring, and low-cost fabrication. Improvements in the areas of aerodynamics and systems are examined. The environmental problems caused by engine emissions, airport noise, and sonic boom are studied. The characteristics of the aircraft designed to include these technical advances are described.

  18. EarthScope's Transportable Array: Advancing Eastward

    NASA Astrophysics Data System (ADS)

    Busby, R. W.; Vernon, F.; Newman, R. L.; Astiz, L.

    2006-12-01

    EarthScope's Transportable Array has installed more than 200 high-quality broadband seismic stations over the last 3 years in the western US. These stations have a nominal spacing of 70 km and are part of an eventual 400 station array that migrates from west to east at a rate of 18 stations per month. The full 400 stations will be operating by September 2007. Stations have a residence time of about 2 years before being relocated to the next site. Throughout the continental US, 1623 sites are expected to be occupied. Standardized procedures and protocols have been developed to streamline all aspects of Transportable Array operations, from siting to site construction and installation to equipment purchasing and data archiving. Earned Value Management tools keep facility installation and operation on budget and schedule. A diverse, yet efficient, infrastructure installs and maintains the Transportable Array. Sensors, dataloggers, and other equipment are received and tested by the IRIS PASSCAL Instrument Center and shipped to regional storage facilities. To engage future geoscientists in the project, students are trained to conduct field and analytical reconnaissance to identify suitable seismic station sites. Contract personnel are used for site verification; vault construction; and installation of sensors, power, and communications systems. IRIS staff manages permitting, landowner communications, and station operations and maintenance. Seismic signal quality and metadata are quality-checked at the Array Network Facility at the University of California-San Diego and simultaneously archived at the IRIS Data Management Center in Seattle. Station equipment has been specifically designed for low power, remote, unattended operation and uses diverse two-way IP communications for real-time transmission. Digital cellular services, VSAT satellite, and commercial DSL, cable or wireless transport services are employed. Automatic monitoring of status, signal quality and

  19. Analytical and simulator study of advanced transport

    NASA Technical Reports Server (NTRS)

    Levison, W. H.; Rickard, W. W.

    1982-01-01

    An analytic methodology, based on the optimal-control pilot model, was demonstrated for assessing longitidunal-axis handling qualities of transport aircraft in final approach. Calibration of the methodology is largely in terms of closed-loop performance requirements, rather than specific vehicle response characteristics, and is based on a combination of published criteria, pilot preferences, physical limitations, and engineering judgment. Six longitudinal-axis approach configurations were studied covering a range of handling qualities problems, including the presence of flexible aircraft modes. The analytical procedure was used to obtain predictions of Cooper-Harper ratings, a solar quadratic performance index, and rms excursions of important system variables.

  20. Systems study of transport aircraft incorporating advanced aluminum alloys

    NASA Technical Reports Server (NTRS)

    Sakata, I. F.

    1982-01-01

    A study was performed to quantify the potential benefits of utilizing advanced aluminum alloys in commercial transport aircraft and to define the effort necessary to develop fully the alloys to a viable commercial production capability. The comprehensive investigation (1) established realistic advanced aluminum alloy property goals to maximize aircraft systems effectiveness (2) identified performance and economic benefits of incorporating the advanced alloy in future advanced technology commercial aircraft designs (3) provided a recommended plan for development and integration of the alloys into commercial aircraft production (4) provided an indication of the timing and investigation required by the metal producing industry to support the projected market and (5) evaluate application of advanced aluminum alloys to other aerospace and transit systems as a secondary objective. The results of the investigation provided a roadmap and identified key issues requiring attention in an advanced aluminum alloy and applications technology development program.

  1. Advancing Transportation through Vehicle Electrification - PHEV

    SciTech Connect

    Bazzi, Abdullah; Barnhart, Steven

    2014-12-31

    FCA US LLC viewed the American Recovery and Reinvestment Act (ARRA) as an historic opportunity to learn about and develop PHEV technologies and create the FCA US LLC engineering center for Electrified Powertrains. The ARRA funding supported FCA US LLC’s light-duty electric drive vehicle and charging infrastructure-testing activities and enabled FCA US LLC to utilize the funding on advancing Plug-in Hybrid Electric Vehicle (PHEV) technologies for production on future programs. FCA US LLC intended to develop the next-generations of electric drive and energy batteries through a properly paced convergence of standards, technology, components and common modules. To support the development of a strong, commercially viable supplier base, FCA US LLC also utilized this opportunity to evaluate various designated component and sub-system suppliers. The original proposal of this project was submitted in May 2009 and selected in August 2009. The project ended in December 2014.

  2. Advanced transport design using multidisciplinary design optimization

    NASA Technical Reports Server (NTRS)

    Barnum, Jennifer; Bathras, Curt; Beene, Kirk; Bush, Michael; Kaupin, Glenn; Lowe, Steve; Sobieski, Ian; Tingen, Kelly; Wells, Douglas

    1991-01-01

    This paper describes the results of the first implementation of multidisciplinary design optimisation (MDO) techniques by undergraduates ina design course. The objective of the work was to design a civilian transport aircraft of the Boeing 777 class. The first half of the two semester design course consisted of application of traditional sizing methods and techniques to form a baseline aircraft. MDO techniques were then applied to this baseline design. This paper describes the evolution of the design with special emphasis on the application of MDO techniques, and presents the results of four iterations through the design space. Minimization of take-off gross weight was the goal of the optimization process. The resultant aircraft derived from the MDO procedure weighed approximately 13,382 lbs (2.57 percent) less than the baseline aircraft.

  3. Advanced Institute for Leadership Personnel in Learning Disabilities. Final Report.

    ERIC Educational Resources Information Center

    Kass, Corrine, Ed.

    Reported upon is an institute involving 87 participants representing leadership personnel in the field of learning disabilities, held December 3-6, 1969, in Tucson, Arizona. The institute's purpose was to upgrade the leadership personnel through exchange of information on issues in pre- and in-service training programs. Historical background,…

  4. Assessment of the impact of advanced air-transport technology

    NASA Technical Reports Server (NTRS)

    Maxwell, R. L.; Dickinson, L. V., Jr.

    1981-01-01

    The long term prospects for commercial supersonic transportation appear attractive enough to keep supersonic research active and reasonably healthy. On the other hand, the uncertainties surrounding an advanced supersonic transport, (AST) specifically fuel price, fuel availability and noise, are too significant to warrant an accelerated research and development program until they are better resolved. It is estimated that an AST could capture about $50 billion (1979 dollars) of the potential $150 billion in sales up to the year 2010.

  5. Economic impact of applying advanced technologies to transport airplanes.

    NASA Technical Reports Server (NTRS)

    Carline, A. J. K.

    1972-01-01

    Various technologies have been studied which could have application to the design of future transport airplanes. These technologies include the use of supercritical aerodynamics, composite materials, and active control systems, together with advanced engine designs that provide lower noise and pollutant levels. The economic impact of each technology is shown for a typical fleet of 195-passenger, transcontinental commercial transports cruising at both 0.9M and 0.98M. Comparisons are made with conventional transports cruising at 0.82M. Effects of combining the technologies are discussed. An R & D program aimed at bringing the technologies to fruition is outlined.

  6. Measure for Measure: Advancement's Role in Assessments of Institutional Quality.

    ERIC Educational Resources Information Center

    Wedekind, Annie; Pollack, Rachel H.

    2002-01-01

    Explores how accreditation, bond ratings, and magazine rankings--including advancement's role in these assessments--continue to be incomplete and controversial indicators of educational quality. Asserts that advancement officers should work to demonstrate the importance of their efforts, such as increasing endowments and alumni support, within the…

  7. Hazard alerting and situational awareness in advanced air transport cockpits

    NASA Technical Reports Server (NTRS)

    Hansman, R. J.; Wanke, Craig; Kuchar, James; Mykityshyn, Mark; Hahn, Edward; Midkiff, Alan

    1992-01-01

    An overview of the Advanced Cockpit Simulation Facility at the Massachusetts Institute of Technology is presented. Though detailed results depend on the specific application, graphical presentation of flight control and alert information has generally been found to be effective for situational awareness and subjectively selected by flight crews. Graphical display is most effective when it is consistent with the pilots cognitive map of the process being displayed or of the situation.

  8. Institutional Advancement and Spectator Sports: The Importance of Television

    ERIC Educational Resources Information Center

    Anctil, Eric

    2009-01-01

    The significant increase in televised intercollegiate athletics over the past couple of decades presents institutions with a set of powerful opportunities to reach external constituents in ways that translate into donations and applications. Given the broad reach of television and its power in developing a university or college as a brand, it may…

  9. Advanced Engineering Environments for Space Transportation System Development

    NASA Technical Reports Server (NTRS)

    Thomas, L. Dale; Smith, Charles A.; Beveridge, James

    2000-01-01

    There are significant challenges facing today's launch vehicle industry. Global competition, more complex products, geographically-distributed design teams, demands for lower cost, higher reliability and safer vehicles, and the need to incorporate the latest technologies quicker, all face the developer of a space transportation system. Within NASA, multiple technology development and demonstration projects are underway toward the objectives of safe, reliable, and affordable access to space. New information technologies offer promising opportunities to develop advanced engineering environments to meet these challenges. Significant advances in the state-of-the-art of aerospace engineering practice are envisioned in the areas of engineering design and analytical tools, cost and risk tools, collaborative engineering, and high-fidelity simulations early in the development cycle. At the Marshall Space Flight Center, work has begun on development of an advanced engineering environment specifically to support the design, modeling, and analysis of space transportation systems. This paper will give an overview of the challenges of developing space transportation systems in today's environment and subsequently discuss the advanced engineering environment and its anticipated benefits.

  10. Perspectives on Performance Indicators: GCE Advanced Level and Differences Between Institution Types in Cost Effectiveness.

    ERIC Educational Resources Information Center

    Fielding, A.

    1998-01-01

    Applies multilevel models of cost-effectiveness to numerous types of (British) institutions providing courses of instruction in the General Certificate of Education at Advanced Level. Different impressions may be gained about an institution's relative effectiveness when cost considerations are combined with outcome measures. Data evaluation needs…

  11. Advanced Transport Operating System (ATOPS) control display unit software description

    NASA Technical Reports Server (NTRS)

    Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

    1992-01-01

    The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

  12. Applications of advanced transport aircraft in developing countries

    NASA Technical Reports Server (NTRS)

    Gobetz, F. W.; Assarabowski, R. J.; Leshane, A. A.

    1978-01-01

    Four representative market scenarios were studied to evaluate the relative performance of air-and surface-based transportation systems in meeting the needs of two developing contries, Brazil and Indonesia, which were selected for detailed case studies. The market scenarios were: remote mining, low-density transport, tropical forestry, and large cargo aircraft serving processing centers in resource-rich, remote areas. The long-term potential of various aircraft types, together with fleet requirements and necessary technology advances, is determined for each application.

  13. Colleges and Institutes: Advanced Skills for the Health Sector

    ERIC Educational Resources Information Center

    Association of Canadian Community Colleges, 2010

    2010-01-01

    This report provides the recommendations made by the Association of Canadian Community Colleges (ACCC) to the House of Commons Standing Committee on Health based from its examination on the health and human resources issues in Canada. Colleges are the advanced skills educators of choice. Aligned with the needs of employers, and operating on the…

  14. The Advancement President and the Academy: Profiles in Institutional Leadership. Series on Higher Education.

    ERIC Educational Resources Information Center

    Murphy, Mary Kay, Ed.

    This book presents 15 essays concerning the growing importance of institutional advancement experience to winning and successfully conducting a college or university presidency. This is a series of essays by successful university CEOs who achieved their positions from an advancement background and who clearly understand the importance of…

  15. Advanced Transport Operating System (ATOPS) utility library software description

    NASA Technical Reports Server (NTRS)

    Clinedinst, Winston C.; Slominski, Christopher J.; Dickson, Richard W.; Wolverton, David A.

    1993-01-01

    The individual software processes used in the flight computers on-board the Advanced Transport Operating System (ATOPS) aircraft have many common functional elements. A library of commonly used software modules was created for general uses among the processes. The library includes modules for mathematical computations, data formatting, system database interfacing, and condition handling. The modules available in the library and their associated calling requirements are described.

  16. National Advanced Drilling and Excavation Technologies Institute. Status report, March 1997

    SciTech Connect

    Peterson, C.

    1997-12-31

    The National Advanced Drilling and Excavation Technologies (NADET) program is intended to pool support, talent, and technologies of the industries dependent upon drilling and excavation technologies to initiate, coordinate, and sustain programs capable of developing substantial technological advances. The NADET Institute has been funded by the DOE Office of Geothermal Technologies and is now supporting seven projects aimed at advanced geothermal drilling technologies. The Institute seeks to broaden its base of funding and technological support from both government and industry sources. Encouraging progress has been made with the support of dues-paying industrial members and industrial sponsorship of a substantial drilling research study.

  17. Earth Institute at Columbia University ADVANCE Program: Addressing Needs for Women in Earth and Environmental Sciences

    NASA Astrophysics Data System (ADS)

    Bell, R. E.; Cane, M.; Mutter, J.; Miller, R.; Pfirman, S.; Laird, J.

    2004-12-01

    The Earth Institute has received a major NSF ADVANCE grant targeted at increasing the participation and advancement of women scientists and engineers in the Academy through institutional transformation. The Earth Institute at Columbia University includes 9 research institutes including Lamont-Doherty Earth Observatory, Center for Environmental Research and Conservation (CERC), Center for International Earth Science Information Network (CIESIN), International Research Institute (IRI) for Climate Prediction, Earth Engineering Center, NASA-Goddard Institute for Space Studies, Center for Risks and Hazards, Center for Globalization and Sustainable Development, and Center for Global Health and Economic Development and six academic departments including Ecology, Evolution and Environmental Biology (E3B, School of Arts and Sciences), Earth and Environmental Engineering (DEEE, School of Engineering and Applied Sciences), Department of Environmental Health (School of Public Health), Department of Earth and Environmental Sciences (DEES, School of Arts and Sciences), Department of International and Public Affairs (School of International and Policy Affairs), and Barnard College Department of Environmental Science. The Earth Institute at Columbia University's ADVANCE program is based both on a study of the status of women at Columbia and research on the progression of women in science elsewhere. The five major targets of the Columbia ADVANCE program are to (1) change the demographics of the faculty through intelligent hiring practices, (2) provide support to women scientists through difficult life transitions including elder care and adoption or birth of a child, (3) enhance mentoring and networking opportunities, (4) implement transparent promotion procedures and policies, and (5) conduct an institutional self study. The Earth Institute ADVANCE program is unique in that it addresses issues that tend to manifest themselves in the earth and environmental fields, such as extended

  18. Advanced Reactors Thermal Energy Transport for Process Industries

    SciTech Connect

    P. Sabharwall; S.J. Yoon; M.G. McKellar; C. Stoots; George Griffith

    2014-07-01

    The operation temperature of advanced nuclear reactors is generally higher than commercial light water reactors and thermal energy from advanced nuclear reactor can be used for various purposes such as liquid fuel production, district heating, desalination, hydrogen production, and other process heat applications, etc. Some of the major technology challenges that must be overcome before the advanced reactors could be licensed on the reactor side are qualification of next generation of nuclear fuel, materials that can withstand higher temperature, improvement in power cycle thermal efficiency by going to combined cycles, SCO2 cycles, successful demonstration of advanced compact heat exchangers in the prototypical conditions, and from the process side application the challenge is to transport the thermal energy from the reactor to the process plant with maximum efficiency (i.e., with minimum temperature drop). The main focus of this study is on doing a parametric study of efficient heat transport system, with different coolants (mainly, water, He, and molten salts) to determine maximum possible distance that can be achieved.

  19. Advanced propulsion for LEO-Moon transport. 1: A method for evaluating advanced propulsion performance

    NASA Technical Reports Server (NTRS)

    Stern, Martin O.

    1992-01-01

    This report describes a study to evaluate the benefits of advanced propulsion technologies for transporting materials between low Earth orbit and the Moon. A relatively conventional reference transportation system, and several other systems, each of which includes one advanced technology component, are compared in terms of how well they perform a chosen mission objective. The evaluation method is based on a pairwise life-cycle cost comparison of each of the advanced systems with the reference system. Somewhat novel and economically important features of the procedure are the inclusion not only of mass payback ratios based on Earth launch costs, but also of repair and capital acquisition costs, and of adjustments in the latter to reflect the technological maturity of the advanced technologies. The required input information is developed by panels of experts. The overall scope and approach of the study are presented in the introduction. The bulk of the paper describes the evaluation method; the reference system and an advanced transportation system, including a spinning tether in an eccentric Earth orbit, are used to illustrate it.

  20. Advancing institutional anomie theory: a microlevel examination connecting culture, institutions, and deviance.

    PubMed

    Muftić, Lisa R

    2006-12-01

    Institutional anomie theory (IAT) contends that crime can be explained by an examination of American society, particularly the exaggerated emphasis on economic success inherent in American culture, which has created a "cheating orientation" that permeates structural institutions, including academia. Consistent with its macrosocial perspective, previous tests of IAT have examined IAT variables at the structural level only. The current study tests the robustness of IAT by operationalizing IAT variables at the individual level and looking at a minor form of deviance, student cheating. The author also examines the role statistical modeling has in testing the theory at the microlevel. Undergraduates, 122 American born and 48 international, were surveyed about their cheating behaviors and adherence to economic goal orientations. Results related to the hypothesis that American students, relative to foreign-born students, will have an increased adherence to economic goal orientations that increase cheating behaviors are presented, as are suggestions for future studies.

  1. Study of ion beam transport from the SECRAL electron cyclotron resonance ion source at the Institute of Modern Physics.

    PubMed

    Cao, Y; Lu, W; Zhang, W H; Sha, S; Yang, Y; Ma, B H; Wang, H; Zhu, Y H; Guo, J W; Fang, X; Lin, S H; Li, X X; Feng, Y C; Li, J Y; Zhao, H Y; Ma, H Y; Zhang, X Z; Guo, X H; Wu, Q; Sun, L T; Zhao, H W; Xie, D Z

    2012-02-01

    Ion beam transport from the Superconducting Electron Cyclotron Resonance ion source with Advanced design in Lanzhou (SECRAL) electron cyclotron resonance ion source was studied at the Institute of Modern Physics during 2010. Particle-in-cell simulations and experimental results have shown that both space charge and magnetic aberrations lead to a larger beam envelope and emittance growth. In the existing SECRAL extraction beam line, it has been shown that raising the solenoid lens magnetic field reduces aberrations in the subsequent dipole and results in lower emittance. Detailed beam emittance measurements are presented in this paper.

  2. Advanced Air Transportation Technologies Project, Final Document Collection

    NASA Technical Reports Server (NTRS)

    Mogford, Richard H.; Wold, Sheryl (Editor)

    2008-01-01

    This CD ROM contains a compilation of the final documents of the Advanced Air Transportation Technologies (AAIT) project, which was an eight-year (1996 to 2004), $400M project managed by the Airspace Systems Program office, which was part of the Aeronautics Research Mission Directorate at NASA Headquarters. AAIT focused on developing advanced automation tools and air traffic management concepts that would help improve the efficiency of the National Airspace System, while maintaining or enhancing safety. The documents contained in the CD are final reports on AAIT tasks that serve to document the project's accomplishments over its eight-year term. Documents include information on: Advanced Air Transportation Technologies, Autonomous Operations Planner, Collaborative Arrival Planner, Distributed Air/Ground Traffic Management Concept Elements 5, 6, & 11, Direct-To, Direct-To Technology Transfer, Expedite Departure Path, En Route Data Exchange, Final Approach Spacing Tool - (Active and Passive), Multi-Center Traffic Management Advisor, Multi Center Traffic Management Advisor Technology Transfer, Surface Movement Advisor, Surface Management System, Surface Management System Technology Transfer and Traffic Flow Management Research & Development.

  3. Fixed Wing Project: Technologies for Advanced Air Transports

    NASA Technical Reports Server (NTRS)

    Del Rosario, Ruben; Koudelka, John M.; Wahls, Richard A.; Madavan, Nateri

    2014-01-01

    The NASA Fundamental Aeronautics Fixed Wing (FW) Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. Multidisciplinary advances are required in aerodynamic efficiency to reduce drag, structural efficiency to reduce aircraft empty weight, and propulsive and thermal efficiency to reduce thrust-specific energy consumption (TSEC) for overall system benefit. Additionally, advances are required to reduce perceived noise without adversely affecting drag, weight, or TSEC, and to reduce harmful emissions without adversely affecting energy efficiency or noise.The presentation will highlight the Fixed Wing project vision of revolutionary systems and technologies needed to achieve these challenging goals. Specifically, the primary focus of the FW Project is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe.

  4. NASA Noise Reduction Program for Advanced Subsonic Transports

    NASA Technical Reports Server (NTRS)

    Stephens, David G.; Cazier, F. W., Jr.

    1995-01-01

    Aircraft noise is an important byproduct of the world's air transportation system. Because of growing public interest and sensitivity to noise, noise reduction technology is becoming increasingly important to the unconstrained growth and utilization of the air transportation system. Unless noise technology keeps pace with public demands, noise restrictions at the international, national and/or local levels may unduly constrain the growth and capacity of the system to serve the public. In recognition of the importance of noise technology to the future of air transportation as well as the viability and competitiveness of the aircraft that operate within the system, NASA, the FAA and the industry have developed noise reduction technology programs having application to virtually all classes of subsonic and supersonic aircraft envisioned to operate far into the 21st century. The purpose of this paper is to describe the scope and focus of the Advanced Subsonic Technology Noise Reduction program with emphasis on the advanced technologies that form the foundation of the program.

  5. NASA's Advanced Space Transportation Program: A Materials Overview

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.

    1999-01-01

    The realization of low-cost assess to space is one of NASA's three principal goals or "pillars" under the Office of Aero-Space Technology. In accordance with the goals of this pillar, NASA's primary space transportation technology role is to develop and demonstrate next-generation technologies to enable the commercial launch industry to develop full-scale, low cost, highly reliable space launchers. The approach involves both ground-based technology demonstrations and flight demonstrators, including the X-33, X-34, Bantam, Reusable Launch Vehicle (RLV), and future experimental vehicles. Next generation space transportation vehicles and propulsion systems will require the development and implementation of advanced materials and processes. This presentation will provide an overview of advanced materials efforts which are focused on the needs of next generation space transportation systems. Applications described will include ceramic matrix composite (CMC) integrally bladed turbine disk (blisk); actively cooled CMC nozzle ramp for the aerospike engine; ablative thrust chamber/nozzle; and metal matrix composite turbomachinery housings.

  6. Project for the Institution of an Advanced Course in Physics

    NASA Astrophysics Data System (ADS)

    Teodorani, M.; Nobili, G.

    2006-06-01

    A project for an advanced course in physics at the master level, is presented in great detail. The goal of this project is to create a specific and rigorous training for those who want to carry out experimental and theoretical research on "anomalies" in physical science, especially from the point of view of atmospheric physics, plasma physics, photonic physics, biophysics, astronomy and astrophysics. A specific training in powering mental skills is planned as well. The planned teaching program is presented as a two-year course where the following subjects are intended to be taught: cognitive techniques (I and II), radiation physics (I and II), biophysics (I and II), bioastronomy (I and II), history of physics (I and II), didactics of physics, physics of atmospheric plasmas, physics of non-stationary photonic events, physics of non-linear processes, complements of quantum mechanics, quantum informatics, research methodology in physics and astronomy, computer science methods in physics and astronomy, optoelectronics, radioelectronics. Detailed teaching programs, didactics methods, and performance evaluation, are presented for each subject. The technical content of this project is preceded by an ample introduction that shows all the reasons of this kind of physics course, particularly aimed at innovation in physical science.

  7. Technology requirements for advanced earth-orbital transportation systems

    NASA Technical Reports Server (NTRS)

    Haefeli, R. C.; Littler, E. G.; Hurley, J. B.; Winter, M. G.

    1977-01-01

    Areas of advanced technology that are either critical or offer significant benefits to the development of future Earth-orbit transportation systems were identified. Technology assessment was based on the application of these technologies to fully reusable, single-stage-to-orbit (SSTO) vehicle concepts with horizontal landing capability. Study guidelines included mission requirements similar to space shuttle, an operational capability begining in 1995, and main propulsion to be advanced hydrogen-fueled rocket engines. Also evaluated was the technical and economic feasibility of this class of SSTO concepts and the comparative features of three operational take-off modes, which were vertical boost, horizontal sled launch, and horizontal take-off with subsequent inflight fueling. Projections of both normal and accelerated technology growth were made. Figures of merit were derived to provide relative rankings of technology areas. The influence of selected accelerated areas on vehicle design and program costs was analyzed by developing near-optimum point designs.

  8. JB-300: An advanced medium size transport for 2005

    NASA Technical Reports Server (NTRS)

    Debrouwer, Giles; Graham, Katherine; Ison, Jim; Juarez, Vince; Moskalik, Steve; Pankonin, Jon; Weinstein, Arnold

    1993-01-01

    In the fall of 1992, the TAC Team was presented with a Request for Proposal (PFP) for a mid-size (250-350 passenger) commercial transport. The aircraft was to be extremely competitive in the areas of passenger comfort, performance, and economic aspects. Through the use of supercritical airfoils, a technologically advanced Very High By-pass Ratio (VHBR) turbofan engine, a low overall drag configuration, a comparable interior layout, and mild use of composites, the JB-300 offers an economically viable choice to the airlines. The cents per passenger mile of the JB-300 is 1.76, which is considerably lower than current aircraft in the same range. Overall, the JB-300 is a technologically advanced aircraft, which will meet the demands of the 21st century.

  9. Evaluation of undeveloped rocket engine cycle applications to advanced transportation

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Undeveloped pump-fed, liquid propellant rocket engine cycles were assessed and evaluated for application to Next Manned Transportation System (NMTS) vehicles, which would include the evolving Space Transportation System (STS Evolution), the Personnel Launch System (PLS), and the Advanced Manned Launch System (AMLS). Undeveloped engine cycles selected for further analysis had potential for increased reliability, more maintainability, reduced cost, and improved (or possibly level) performance when compared to the existing SSME and proposed STME engines. The split expander (SX) cycle, the full flow staged combustion (FFSC) cycle, and a hybrid version of the FFSC, which has a LOX expander drive for the LOX pump, were selected for definition and analysis. Technology requirements and issues were identified and analyses of vehicle systems weight deltas using the SX and FFSC cycles in AMLS vehicles were performed. A strawman schedule and cost estimate for FFSC subsystem technology developments and integrated engine system demonstration was also provided.

  10. Advanced High-Temperature, High-Pressure Transport Reactor Gasification

    SciTech Connect

    Michael Swanson; Daniel Laudal

    2008-03-31

    The U.S. Department of Energy (DOE) National Energy Technology Laboratory Office of Coal and Environmental Systems has as its mission to develop advanced gasification-based technologies for affordable, efficient, zero-emission power generation. These advanced power systems, which are expected to produce near-zero pollutants, are an integral part of DOE's Vision 21 Program. DOE has also been developing advanced gasification systems that lower the capital and operating costs of producing syngas for chemical production. A transport reactor has shown potential to be a low-cost syngas producer compared to other gasification systems since its high-throughput-per-unit cross-sectional area reduces capital costs. This work directly supports the Power Systems Development Facility utilizing the KBR transport reactor located at the Southern Company Services Wilsonville, Alabama, site. Over 2800 hours of operation on 11 different coals ranging from bituminous to lignite along with a petroleum coke has been completed to date in the pilot-scale transport reactor development unit (TRDU) at the Energy & Environmental Research Center (EERC). The EERC has established an extensive database on the operation of these various fuels in both air-blown and oxygen-blown modes utilizing a pilot-scale transport reactor gasifier. This database has been useful in determining the effectiveness of design changes on an advanced transport reactor gasifier and for determining the performance of various feedstocks in a transport reactor. The effects of different fuel types on both gasifier performance and the operation of the hot-gas filter system have been determined. It has been demonstrated that corrected fuel gas heating values ranging from 90 to 130 Btu/scf have been achieved in air-blown mode, while heating values up to 230 Btu/scf on a dry basis have been achieved in oxygen-blown mode. Carbon conversions up to 95% have also been obtained and are highly dependent on the oxygen-coal ratio. Higher

  11. Advanced cockpit technology for future civil transport aircraft

    NASA Technical Reports Server (NTRS)

    Hatfield, Jack J.; Parrish, Russell V.

    1990-01-01

    A review is presented of advanced cockpit technology for future civil transport aircraft, covering the present state-of-the-art and major technologies, including flat-panel displays, graphics and pictorial displays. Pilot aiding/automation/human-centered design and imaging sensor/flight systems technology (for low-visibility operations) are also presented. NASA Langley Research Center's recent results in pictorial displays and on future developments in large-screen display technologies are discussed. Major characteristics foreseen for the future high-speed civil transport include fault-tolerant digital avionics and controls/displays with extensive human-centered automation, and unusually clean, uncluttered interface with natural crew interaction via touch, voice/tactile means.

  12. Terminal area considerations for an advanced CTOL transport aircraft

    NASA Technical Reports Server (NTRS)

    Sussman, M. B.

    1975-01-01

    Projected future conditions at large urban airports were used to identify design objectives for a long-haul, advanced transport airplane introduced for operation in the mid-1980s. Operating constraints associated with airport congestion and aircraft noise and emissions were of central interest. In addition, some of the interaction of these constraints with aircraft fuel usage were identified. The study allowed for advanced aircraft design features consistent with the future operating period. A baseline 200 passenger airplane design was modified to comply with design requirements imposed by terminal area constraints. Specific design changes included: (1) modification of engine arrangement; wing planform; (2) drag and spoiler surfaces; (3) secondary power systems; (4) brake and landing gear characteristics; and (5) the aircraft avionics. These changes, based on exploratory design estimates and allowing for technology advance, were judged to enable the airplane to: reduce wake turbulence; handle steeper descent paths with fewer limitation due to engine characteristics; reduce runway occupancy times; improve community noise contours; and reduce the total engine emittants deposited in the terminal area. The penalties to airplane performance and operating cost associated with improving the terminal area characteristics of the airplane were assessed. Finally, key research problems requiring solution in order to validate the assumed advanced airplane technology were identified.

  13. Data Compression Techniques for Advanced Space Transportation Systems

    NASA Technical Reports Server (NTRS)

    Bradley, William G.

    1998-01-01

    Advanced space transportation systems, including vehicle state of health systems, will produce large amounts of data which must be stored on board the vehicle and or transmitted to the ground and stored. The cost of storage or transmission of the data could be reduced if the number of bits required to represent the data is reduced by the use of data compression techniques. Most of the work done in this study was rather generic and could apply to many data compression systems, but the first application area to be considered was launch vehicle state of health telemetry systems. Both lossless and lossy compression techniques were considered in this study.

  14. Advanced composite vertical stabilizer for DC-10 transport aircraft

    NASA Technical Reports Server (NTRS)

    Stephens, C. O.

    1979-01-01

    Structural design, tooling, fabrication, and test activities are reported for a program to develop an advanced composite vertical stabilizer (CVS) for the DC 10 Commercial Transport Aircraft. Structural design details are described and the status of structural and weight analyses are reported. A structural weight reduction of 21.7% is currently predicted. Test results are discussed for sine wave stiffened shear webs containing representative of the CVS spar webs and for lightning current transfer and tests on a panel representative of the CVS skins.

  15. First 3 years of operation of RIACS (Research Institute for Advanced Computer Science) (1983-1985)

    NASA Technical Reports Server (NTRS)

    Denning, P. J.

    1986-01-01

    The focus of the Research Institute for Advanced Computer Science (RIACS) is to explore matches between advanced computing architectures and the processes of scientific research. An architecture evaluation of the MIT static dataflow machine, specification of a graphical language for expressing distributed computations, and specification of an expert system for aiding in grid generation for two-dimensional flow problems was initiated. Research projects for 1984 and 1985 are summarized.

  16. Greater-Than-Class C Low-Level Radioactive Waste Transportation Strategy report and institutional plan

    SciTech Connect

    Schmitt, R.C.; Tyacke, M.J.

    1995-01-01

    This document contains two parts. Part I, Greater-Than-Class-C Low-Level Radioactive Waste Transportation Strategy, addresses the requirements, responsibilities, and strategy to transport and receive these wastes. The strategy covers (a) transportation packaging, which includes shipping casks and waste containers; (b) transportation operations relating to the five facilities involved in transportation, i.e., waste originator, interim storage, dedicated storage, treatment, and disposal; (c) system safety and risk analysis; (d) routes; (e) emergency preparedness and response; and (o safeguards and security. A summary of strategic actions is provided at the conclusion of Part 1. Part II, Institutional Plan for Greater-Than-Class C Low-Level Radioactive Waste Packaging and Transportation, addresses the assumptions, requirements, and institutional plan elements and actions. As documented in the Strategy and Institutional Plan, the most challenging issues facing the GTCC LLW Program shipping campaign are institutional issues closely related to the strategy. How the Program addresses those issues and demonstrates to the states, local governments, and private citizens that the shipments can and will be made safely will strongly affect the success or failure of the campaign.

  17. 75 FR 76617 - Use of Community Development Loans by Community Financial Institutions To Secure Advances...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ... definition of ``community development'' as proposed. The final rule also will transfer the advances and new... community development lending is not new in banking law and is a well-developed concept as evidenced by the... RIN 2590-AA24 Use of Community Development Loans by Community Financial Institutions To...

  18. The Community College President: Working with and through the Media to Advance the Institution

    ERIC Educational Resources Information Center

    Carringer, Paul T.

    2013-01-01

    The purpose of this study was to examine how community college presidents successfully work with and through the media to advance their institutions. Four successful cases were studied. These success stories came from the list of Paragon Award winners selected annually by the National Council of Marketing and Public Relations (NCMPR) and be cross…

  19. Data Mining and Predictive Modeling in Institutional Advancement: How Ten Schools Found Success. Technical Report

    ERIC Educational Resources Information Center

    Luperchio, Dan

    2009-01-01

    This technical report, produced in partnership by the Council for Advancement and Support of Education (CASE) and SPSS Inc., explores the promise of data mining alumni records at educational institutions. Working with individual alumni records from The Johns Hopkins Zanvyl Krieger School of Arts and Sciences, a predictive regression model is…

  20. Institutional Advancement: A Marketing Perspective. Part II: A Status Report, 1978-79.

    ERIC Educational Resources Information Center

    Moriarty, Daniel F.

    This follow-up report examines the status of the recruitment and retention strategies implemented by Triton College in 1978 as part of an effort to utilize the marketing concept in identifying and meeting changing educational needs. The report first provides operational definitions for "institutional advancement,""marketing concept,""promotion,"…

  1. Strategic Leadership: A Model for Promoting, Sustaining, and Advancing Institutional Significance

    ERIC Educational Resources Information Center

    Scott, Kenneth E.; Johnson, Mimi

    2011-01-01

    This article presents the methods, materials, and manpower required to create a strategic leadership program for promoting, sustaining, and advancing institutional significance. The functionality of the program is based on the Original Case Study Design (OCSD) methodology, in which participants are given actual college issues to investigate from a…

  2. Advanced Placement® Summer Institute: A Survey of Florida AP® Teachers. Research Notes. RN-39

    ERIC Educational Resources Information Center

    Godfrey, Kelly E.

    2009-01-01

    Advanced Placement Program Summer Institute (APSI) courses provide teachers with an overview of the curriculum, structure, and content of specific AP courses. Attention is devoted not only to the development of curriculum but also to teaching strategies and the relationship of the course to the AP Examination. During the summers of 2006 and 2007,…

  3. Developing Research Infrastructure: The Institute for the Advancement of Social Work Research

    ERIC Educational Resources Information Center

    Zlotnik, Joan Levy; Solt, Barbara E.

    2008-01-01

    This article reviews the 15 years of research development efforts of the Institute for the Advancement of Social Work Research (IASWR); delineates IASWR's roles in relation to the social work practice, education, and research communities; presents the transdisciplinary and transorganizational partnerships in which IASWR engages to influence…

  4. Advancing Institutional Effectiveness. The Council of Independent Colleges 2004-2005 Annual Report

    ERIC Educational Resources Information Center

    Council of Independent Colleges, 2005

    2005-01-01

    Advancing the effectiveness of independent colleges and universities has long been central to the mission of the Council of Independent Colleges (CIC). CIC offers its members an exceptionally broad range of initiatives to improve the quality of education and strengthen institutional resources. The number of programs and services being offered has…

  5. Display-based communications for advanced transport aircraft

    NASA Technical Reports Server (NTRS)

    Lee, Alfred T.

    1989-01-01

    The next generation of civil transport aircraft will depend increasingly upon ground-air-ground and satellite data link for information critical to safe and efficient air transportation. Previous studies which examined the concept of display-based communications in addition to, or in lieu of, conventional voice transmissions are reviewed. A full-mission flight simulation comparing voice and display-based communication modes in an advanced transport aircraft is also described. The results indicate that a display-based mode of information transfer does not result in significantly increased aircrew workload, but does result in substantially increased message acknowledgment times when compared to conventional voice transmissions. User acceptance of the display-based communication system was generally high, replicating the findings of previous studies. However, most pilots tested expressed concern over the potential loss of information available from frequency monitoring which might result from the introduction of discrete address communications. Concern was expressed by some pilots for the reduced time available to search for conflicting traffic when using the communications display system. The implications of the findings for the design of display-based communications are discussed.

  6. Thermal blanket insulation for advanced space transportation systems

    NASA Technical Reports Server (NTRS)

    Pusch, Richard H.

    1985-01-01

    The feasibility of weaving Nextel ceramic and Nicalon silicon carbide yarns into integrally woven, three dimensional fluted core fabrics was demonstrated. Parallel face fabrics joined with woven fabric ribs to form triangular cross section flutes between the faces were woven into three single and one double layer configuration. High warp yarn density in the double layer configuration caused considerable yarn breakage during weaving. The flutes of all four fabrics were filled with mandrels made from Q-Fiber Felt and FRCI-20-12 to form candidate insulation panels for advanced Space Transportation Systems. Procedures for preparing and inserting the mandrels were developed. Recommendations are made on investigating alternate methods for filling the flutes with insulation, and for improving the weaving of these types of fabrics.

  7. An advanced concept secondary power systems study for an advanced transport technology aircraft

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The application of advanced technology to the design of an integrated secondary power system for future near-sonic long-range transports was investigated. The study showed that the highest payoff is achieved by utilizing secondary power equipment that contributes to minimum cruise drag. This is best accomplished by the use of the dedicated auxiliary power unit concept (inflight APU) as the prime power source for an airplane with a body-mounted engine or by the use of the internal engine generator concept (electrical power extraction from the propulsion engine) for an airplane with a wing-pod-mounted engine.

  8. Advanced Single-Aisle Transport Propulsion Design Options Revisited

    NASA Technical Reports Server (NTRS)

    Guynn, Mark D.; Berton, Jeffrey J.; Tong, Michael T.; Haller, William J.

    2013-01-01

    Future propulsion options for advanced single-aisle transports have been investigated in a number of previous studies by the authors. These studies have examined the system level characteristics of aircraft incorporating ultra-high bypass ratio (UHB) turbofans (direct drive and geared) and open rotor engines. During the course of these prior studies, a number of potential refinements and enhancements to the analysis methodology and assumptions were identified. This paper revisits a previously conducted UHB turbofan fan pressure ratio trade study using updated analysis methodology and assumptions. The changes incorporated have decreased the optimum fan pressure ratio for minimum fuel consumption and reduced the engine design trade-offs between minimizing noise and minimizing fuel consumption. Nacelle drag and engine weight are found to be key drivers in determining the optimum fan pressure ratio from a fuel efficiency perspective. The revised noise analysis results in the study aircraft being 2 to 4 EPNdB (cumulative) quieter due to a variety of reasons explained in the paper. With equal core technology assumed, the geared engine architecture is found to be as good as or better than the direct drive architecture for most parameters investigated. However, the engine ultimately selected for a future advanced single-aisle aircraft will depend on factors beyond those considered here.

  9. Engine Concept Study for an Advanced Single-Aisle Transport

    NASA Technical Reports Server (NTRS)

    Guynn, Mark D.; Berton, Jeffrey J.; Fisher, Kenneth L.; Haller, William J.; Tong, Michael; Thurman, Douglas R.

    2009-01-01

    The desire for higher engine efficiency has resulted in the evolution of aircraft gas turbine engines from turbojets, to low bypass ratio, first generation turbofans, to today's high bypass ratio turbofans. Although increased bypass ratio has clear benefits in terms of propulsion system metrics such as specific fuel consumption, these benefits may not translate into aircraft system level benefits due to integration penalties. In this study, the design trade space for advanced turbofan engines applied to a single aisle transport (737/A320 class aircraft) is explored. The benefits of increased bypass ratio and associated enabling technologies such as geared fan drive are found to depend on the primary metrics of interest. For example, bypass ratios at which mission fuel consumption is minimized may not require geared fan technology. However, geared fan drive does enable higher bypass ratio designs which result in lower noise. The results of this study indicate the potential for the advanced aircraft to realize substantial improvements in fuel efficiency, emissions, and noise compared to the current vehicles in this size class.

  10. Advanced Configurations for Very Large Subsonic Transport Airplanes

    NASA Technical Reports Server (NTRS)

    McMasters, John H.; Paisley, David J.; Hubert, Richard J.; Kroo, Ilan; Bofah, Kwasi K.; Sullivan, John P.; Drela, Mark

    1996-01-01

    Recent aerospace industry interest in developing a subsonic commercial transport airplane with 50 percent greater passenger capacity than the largest existing aircraft in this category (the Boeing 747-400 with approximately 400-450 seats) has generated a range of proposals based largely on the configuration paradigm established nearly 50 years ago with the Boeing B-47 bomber. While this basic configuration paradigm has come to dominate subsonic commercial airplane development since the advent of the Boeing 707/Douglas DC-8 in the mid-1950's, its extrapolation to the size required to carry more than 600-700 passengers raises several questions. To explore these and a number of related issues, a team of Boeing, university, and NASA engineers was formed under the auspices of the NASA Advanced Concepts Program. The results of a Research Analysis focused on a large, unconventional transport airplane configuration for which Boeing has applied for a patent are the subject of this report. It should be noted here that this study has been conducted independently of the Boeing New Large Airplane (NLA) program, and with the exception of some generic analysis tools which may be common to this effort and the NLA (as will be described later), no explicit Boeing NLA data other than that published in the open literature has been used in the conduct of the study reported here.

  11. Advanced fuel cells for transportation applications. Final report

    SciTech Connect

    1998-02-10

    This Research and Development (R and D) contract was directed at developing an advanced technology compressor/expander for supplying compressed air to Proton Exchange Membrane (PEM) fuel cells in transportation applications. The objective of this project was to develop a low-cost high-efficiency long-life lubrication-free integrated compressor/expander utilizing scroll technology. The goal of this compressor/expander was to be capable of providing compressed air over the flow and pressure ranges required for the operation of 50 kW PEM fuel cells in transportation applications. The desired ranges of flow, pressure, and other performance parameters were outlined in a set of guidelines provided by DOE. The project consisted of the design, fabrication, and test of a prototype compressor/expander module. The scroll CEM development program summarized in this report has been very successful, demonstrating that scroll technology is a leading candidate for automotive fuel cell compressor/expanders. The objectives of the program are: develop an integrated scroll CEM; demonstrate efficiency and capacity goals; demonstrate manufacturability and cost goals; and evaluate operating envelope. In summary, while the scroll CEM program did not demonstrate a level of performance as high as the DOE guidelines in all cases, it did meet the overriding objectives of the program. A fully-integrated, low-cost CEM was developed that demonstrated high efficiency and reliable operation throughout the test program. 26 figs., 13 tabs.

  12. Consumer Views on Transportation and Advanced Vehicle Technologies

    SciTech Connect

    Singer, Mark

    2015-09-01

    Vehicle manufacturers, U.S. Department of Energy laboratories, universities, private researchers, and organizations from countries around the globe are pursuing advanced vehicle technologies that aim to reduce gasoline and diesel consumption. This report details study findings of broad American public sentiments toward issues surrounding advanced vehicle technologies and is supported by the U.S. Department of Energy Vehicle Technology Office (VTO) in alignment with its mission to develop and deploy these technologies to improve energy security, increase mobility flexibility, reduce transportation costs, and increase environmental sustainability. Understanding and tracking consumer sentiments can influence the prioritization of development efforts by identifying barriers to and opportunities for broad acceptance of new technologies. Predicting consumer behavior toward developing technologies and products is inherently inexact. A person's stated preference given in an interview about a hypothetical setting may not match the preference that is demonstrated in an actual situation. This difference makes tracking actual consumer actions ultimately more valuable in understanding potential behavior. However, when developing technologies are not yet available and actual behaviors cannot be tracked, stated preferences provide some insight into how consumers may react in new circumstances. In this context this report provides an additional source to validate data and a new resource when no data are available. This report covers study data captured from December 2005 through June 2015 relevant to VTO research efforts at the time of the studies. Broadly the report covers respondent sentiments about vehicle fuel economy, future vehicle technology alternatives, ethanol as a vehicle fuel, plug-in electric vehicles, and willingness to pay for vehicle efficiency. This report represents a renewed effort to publicize study findings and make consumer sentiment data available to

  13. Automatic braking system modification for the Advanced Transport Operating Systems (ATOPS) Transportation Systems Research Vehicle (TSRV)

    NASA Technical Reports Server (NTRS)

    Coogan, J. J.

    1986-01-01

    Modifications were designed for the B-737-100 Research Aircraft autobrake system hardware of the Advanced Transport Operating Systems (ATOPS) Program at Langley Research Center. These modifications will allow the on-board flight control computer to control the aircraft deceleration after landing to a continuously variable level for the purpose of executing automatic high speed turn-offs from the runway. A bread board version of the proposed modifications was built and tested in simulated stopping conditions. Test results, for various aircraft weights, turnoff speed, winds, and runway conditions show that the turnoff speeds are achieved generally with errors less than 1 ft/sec.

  14. Continued Development and Application of Circulation Control Pneumatic Technology to Advanced Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Englar, Robert J.

    1998-01-01

    Personnel of the Georgia Tech Research Institute (GTRI) Aerospace and Transportation Lab have completed a four-year grant program to develop and evaluate the pneumatic aerodynamic technology known as Circulation Control (CC) or Circulation Control Wing (CCW) for advanced transport aircraft. This pneumatic technology, which employs low-level blowing from tangential slots over round or near-round trailing edges of airfoils, greatly augments the circulation around a lifting or control surface and thus enhances the aerodynamic forces and moments generated by that surface. Two-dimensional force augmentations as high as 80 times the input blowing momentum coefficient have been recorded experimentally for these blown devices, thus providing returns of 8000% on the jet momentum expended. A further benefit is the absence of moving parts such as mechanical flaps, slats, spoilers, ailerons, elevators and rudders from these pneumatic surfaces, or the use of only very small, simple, blown aerodynamic surfaces on synergistic designs which integrate the lift, drag and control surfaces. The application of these devices to advanced aircraft can offer significant benefits in their performance, efficiency, simplicity, reliability, economic cost of operation, noise reduction, and safety of flight. To further develop and evaluate this potential, this research effort was conducted by GTRI under grant for the NASA Langley Research Center, Applied Aerodynamics Division, Subsonic Aerodynamics Branch, between June 14, 1993 and May 31, 1997.

  15. Recovery Act - Sustainable Transportation: Advanced Electric Drive Vehicle Education Program

    SciTech Connect

    Caille, Gary

    2013-12-13

    The collective goals of this effort include: 1) reach all facets of this society with education regarding electric vehicles (EV) and plug–in hybrid electric vehicles (PHEV), 2) prepare a workforce to service these advanced vehicles, 3) create web–based learning at an unparalleled level, 4) educate secondary school students to prepare for their future and 5) train the next generation of professional engineers regarding electric vehicles. The Team provided an integrated approach combining secondary schools, community colleges, four–year colleges and community outreach to provide a consistent message (Figure 1). Colorado State University Ventures (CSUV), as the prime contractor, plays a key program management and co–ordination role. CSUV is an affiliate of Colorado State University (CSU) and is a separate 501(c)(3) company. The Team consists of CSUV acting as the prime contractor subcontracted to Arapahoe Community College (ACC), CSU, Motion Reality Inc. (MRI), Georgia Institute of Technology (Georgia Tech) and Ricardo. Collaborators are Douglas County Educational Foundation/School District and Gooru (www.goorulearning.org), a nonprofit web–based learning resource and Google spin–off.

  16. Delta Advanced Reusable Transport (DART): An alternative manned spacecraft

    NASA Astrophysics Data System (ADS)

    Lewerenz, T.; Kosha, M.; Magazu, H.

    Although the current U.S. Space Transportation System (STS) has proven successful in many applications, the truth remains that the space shuttle is not as reliable or economical as was once hoped. In fact, the Augustine Commission on the future of the U.S. Space Program has recommended that the space shuttle only be used on missions directly requiring human capabilities on-orbit and that the shuttle program should eventually be phased out. This poses a great dilemma since the shuttle provides the only current or planned U.S. means for human access to space at the same time that NASA is building toward a permanent manned presence. As a possible solution to this dilemma, it is proposed that the U.S. begin development of an Alternative Manned Spacecraft (AMS). This spacecraft would not only provide follow-on capability for maintaining human space flight, but would also provide redundancy and enhanced capability in the near future. Design requirements for the AMS studied include: (1) capability of launching on one of the current or planned U.S. expendable launch vehicles (baseline McDonnell Douglas Delta II model 7920 expendable booster); (2) application to a wide variety of missions including autonomous operations, space station support, and access to orbits and inclinations beyond those of the space shuttle; (3) low enough costing to fly regularly in augmentation of space shuttle capabilities; (4) production surge capabilities to replace the shuttle if events require it; (5) intact abort capability in all flight regimes since the planned launch vehicles are not man-rated; (6) technology cut-off date of 1990; and (7) initial operational capability in 1995. In addition, the design of the AMS would take advantage of scientific advances made in the 20 years since the space shuttle was first conceived. These advances are in such technologies as composite materials, propulsion systems, avionics, and hypersonics.

  17. Delta Advanced Reusable Transport (DART): An alternative manned spacecraft

    NASA Technical Reports Server (NTRS)

    Lewerenz, T.; Kosha, M.; Magazu, H.

    1991-01-01

    Although the current U.S. Space Transportation System (STS) has proven successful in many applications, the truth remains that the space shuttle is not as reliable or economical as was once hoped. In fact, the Augustine Commission on the future of the U.S. Space Program has recommended that the space shuttle only be used on missions directly requiring human capabilities on-orbit and that the shuttle program should eventually be phased out. This poses a great dilemma since the shuttle provides the only current or planned U.S. means for human access to space at the same time that NASA is building toward a permanent manned presence. As a possible solution to this dilemma, it is proposed that the U.S. begin development of an Alternative Manned Spacecraft (AMS). This spacecraft would not only provide follow-on capability for maintaining human space flight, but would also provide redundancy and enhanced capability in the near future. Design requirements for the AMS studied include: (1) capability of launching on one of the current or planned U.S. expendable launch vehicles (baseline McDonnell Douglas Delta II model 7920 expendable booster); (2) application to a wide variety of missions including autonomous operations, space station support, and access to orbits and inclinations beyond those of the space shuttle; (3) low enough costing to fly regularly in augmentation of space shuttle capabilities; (4) production surge capabilities to replace the shuttle if events require it; (5) intact abort capability in all flight regimes since the planned launch vehicles are not man-rated; (6) technology cut-off date of 1990; and (7) initial operational capability in 1995. In addition, the design of the AMS would take advantage of scientific advances made in the 20 years since the space shuttle was first conceived. These advances are in such technologies as composite materials, propulsion systems, avionics, and hypersonics.

  18. Transport advances in disposable bioreactors for liver tissue engineering.

    PubMed

    Catapano, Gerardo; Patzer, John F; Gerlach, Jörg Christian

    2009-01-01

    Acute liver failure (ALF) is a devastating diagnosis with an overall survival of approximately 60%. Liver transplantation is the therapy of choice for ALF patients but is limited by the scarce availability of donor organs. The prognosis of ALF patients may improve if essential liver functions are restored during liver failure by means of auxiliary methods because liver tissue has the capability to regenerate and heal. Bioartificial liver (BAL) approaches use liver tissue or cells to provide ALF patients with liver-specific metabolism and synthesis products necessary to relieve some of the symptoms and to promote liver tissue regeneration. The most promising BAL treatments are based on the culture of tissue engineered (TE) liver constructs, with mature liver cells or cells that may differentiate into hepatocytes to perform liver-specific functions, in disposable continuous-flow bioreactors. In fact, adult hepatocytes perform all essential liver functions. Clinical evaluations of the proposed BALs show that they are safe but have not clearly proven the efficacy of treatment as compared to standard supportive treatments. Ambiguous clinical results, the time loss of cellular activity during treatment, and the presence of a necrotic core in the cell compartment of many bioreactors suggest that improvement of transport of nutrients, and metabolic wastes and products to or from the cells in the bioreactor is critical for the development of therapeutically effective BALs. In this chapter, advanced strategies that have been proposed over to improve mass transport in the bioreactors at the core of a BAL for the treatment of ALF patients are reviewed.

  19. Transport Advances in Disposable Bioreactors for Liver Tissue Engineering

    NASA Astrophysics Data System (ADS)

    Catapano, Gerardo; Patzer, John F.; Gerlach, Jörg Christian

    Acute liver failure (ALF) is a devastating diagnosis with an overall survival of approximately 60%. Liver transplantation is the therapy of choice for ALF patients but is limited by the scarce availability of donor organs. The prognosis of ALF patients may improve if essential liver functions are restored during liver failure by means of auxiliary methods because liver tissue has the capability to regenerate and heal. Bioartificial liver (BAL) approaches use liver tissue or cells to provide ALF patients with liver-specific metabolism and synthesis products necessary to relieve some of the symptoms and to promote liver tissue regeneration. The most promising BAL treatments are based on the culture of tissue engineered (TE) liver constructs, with mature liver cells or cells that may differentiate into hepatocytes to perform liver-specific functions, in disposable continuous-flow bioreactors. In fact, adult hepatocytes perform all essential liver functions. Clinical evaluations of the proposed BALs show that they are safe but have not clearly proven the efficacy of treatment as compared to standard supportive treatments. Ambiguous clinical results, the time loss of cellular activity during treatment, and the presence of a necrotic core in the cell compartment of many bioreactors suggest that improvement of transport of nutrients, and metabolic wastes and products to or from the cells in the bioreactor is critical for the development of therapeutically effective BALs. In this chapter, advanced strategies that have been proposed over to improve mass transport in the bioreactors at the core of a BAL for the treatment of ALF patients are reviewed.

  20. Advances in Dynamic Transport of Organic Contaminants in Karst Groundwater Systems

    NASA Astrophysics Data System (ADS)

    Padilla, I. Y.; Vesper, D.; Alshawabkeh, A.; Hellweger, F.

    2011-12-01

    Karst groundwater systems develop in soluble rocks such as limestone, and are characterized by high permeability and well-developed conduit porosity. These systems provide important freshwater resources for human consumption and ecological integrity of streams, wetlands, and coastal zones. The same characteristics that make karst aquifers highly productive make them highly vulnerable to contamination. As a result, karst aquifers serve as an important route for contaminants exposure to humans and wildlife. Transport of organic contaminants in karst ground-water occurs in complex pathways influenced by the flow mechanism predominating in the aquifer: conduit-flow dominated systems tend to convey solutes rapidly through the system to a discharge point without much attenuation; diffuse-flow systems, on the other hand, can cause significant solute retardation and slow movement. These two mechanisms represent end members of a wide spectrum of conditions found in karst areas, and often a combination of conduit- and diffuse-flow mechanisms is encountered, where both flow mechanisms can control the fate and transport of contaminants. This is the case in the carbonate aquifers of northern Puerto Rico. This work addresses advances made on the characterization of fate and transport processes in karst ground-water systems characterized by variable conduit and/or diffusion dominated flow under high- and low-flow conditions. It involves laboratory-scale physical modeling and field-scale sampling and historical analysis of contaminant distribution. Statistical analysis of solute transport in Geo-Hydrobed physical models shows the heterogeneous character of transport dynamics in karstic units, and its variability under different flow regimes. Field-work analysis of chlorinated volatile organic compounds and phthalates indicates a large capacity of the karst systems to store and transmit contaminants. This work is part of the program "Puerto Rico Testsite for Exploring Contamination

  1. Strategies for Advancing Women in Physics and other Sciences in an Undergraduate Hispanic Institution (abstract)

    NASA Astrophysics Data System (ADS)

    Ramos, Idalia

    2009-04-01

    For the past 15 years, University of Puerto Rico at Humacao (UPRH) has implemented various efforts to increase participation and promote advancement of women in physics and other sciences. The strategies used include mentoring, collaborating, forming women's organizations, and offering training workshops. The physics program at UPRH is the largest in Puerto Rico with approximately 95 undergraduates. Since 1995, female students in the program have increased from 17% to 32%. Efforts to integrate women in undergraduate research as early as possible in their studies show promising results, with the percentage of women in research increasing from 13% to 60% in the last 13 years. The Faculty in Training (FIT) program, begun in 2003, has supported talented women students interested in academic careers. The first FIT physics student will obtain her PhD in 2009. At the faculty level, UPRH received a first-round US National Science Foundation ADVANCE Institutional Transformation Award in 2001. The ADVANCE legacy at UPRH is evident at levels ranging from changes in individual behaviors to the adoption of institutional policies. A strong network of women in science and their supporters continues to advance this legacy.

  2. Fostering Visions for the Future: A Review of the NASA Institute for Advanced Concepts

    NASA Technical Reports Server (NTRS)

    2009-01-01

    The NASA Institute for Advanced Concepts (NIAC) was formed in 1998 to provide an independent source of advanced aeronautical and space concepts that could dramatically impact how NASA develops and conducts its missions. Until the program's termination in August 2007, NIAC provided an independent open forum, a high-level point of entry to NASA for an external community of innovators, and an external capability for analysis and definition of advanced aeronautics and space concepts to complement the advanced concept activities conducted within NASA. Throughout its 9-year existence, NIAC inspired an atmosphere for innovation that stretched the imagination and encouraged creativity. As requested by Congress, this volume reviews the effectiveness of NIAC and makes recommendations concerning the importance of such a program to NASA and to the nation as a whole, including the proper role of NASA and the federal government in fostering scientific innovation and creativity and in developing advanced concepts for future systems. Key findings and recommendations include that in order to achieve its mission, NASA must have, and is currently lacking, a mechanism to investigate visionary, far-reaching advanced concepts. Therefore, a NIAC-like entity should be reestablished to fill this gap.

  3. Application of advanced technologies to small, short-haul transport aircraft

    NASA Technical Reports Server (NTRS)

    Coussens, T. G.; Tullis, R. H.

    1980-01-01

    The performance and economic benefits available by incorporation of advanced technologies into the small, short haul air transport were assessed. Low cost structure and advanced composite material, advanced turboprop engines and new propellers, advanced high lift systems and active controls; and alternate aircraft configurations with aft mounted engines were investigated. Improvements in fuel consumed and aircraft economics (acquisition cost and direct operating cost) are available by incorporating selected advanced technologies into the small, short haul aircraft.

  4. Advanced transportation system studies. Alternate propulsion subsystem concepts: Propulsion database

    NASA Technical Reports Server (NTRS)

    Levack, Daniel

    1993-01-01

    The Advanced Transportation System Studies alternate propulsion subsystem concepts propulsion database interim report is presented. The objective of the database development task is to produce a propulsion database which is easy to use and modify while also being comprehensive in the level of detail available. The database is to be available on the Macintosh computer system. The task is to extend across all three years of the contract. Consequently, a significant fraction of the effort in this first year of the task was devoted to the development of the database structure to ensure a robust base for the following years' efforts. Nonetheless, significant point design propulsion system descriptions and parametric models were also produced. Each of the two propulsion databases, parametric propulsion database and propulsion system database, are described. The descriptions include a user's guide to each code, write-ups for models used, and sample output. The parametric database has models for LOX/H2 and LOX/RP liquid engines, solid rocket boosters using three different propellants, a hybrid rocket booster, and a NERVA derived nuclear thermal rocket engine.

  5. Development of tailorable advanced blanket insulation for advanced space transportation systems

    NASA Technical Reports Server (NTRS)

    Calamito, Dominic P.

    1987-01-01

    Two items of Tailorable Advanced Blanket Insulation (TABI) for Advanced Space Transportation Systems were produced. The first consisted of flat panels made from integrally woven, 3-D fluted core having parallel fabric faces and connecting ribs of Nicalon silicon carbide yarns. The triangular cross section of the flutes were filled with mandrels of processed Q-Fiber Felt. Forty panels were prepared with only minimal problems, mostly resulting from the unavailability of insulation with the proper density. Rigidizing the fluted fabric prior to inserting the insulation reduced the production time. The procedures for producing the fabric, insulation mandrels, and TABI panels are described. The second item was an effort to determine the feasibility of producing contoured TABI shapes from gores cut from flat, insulated fluted core panels. Two gores of integrally woven fluted core and single ply fabric (ICAS) were insulated and joined into a large spherical shape employing a tadpole insulator at the mating edges. The fluted core segment of each ICAS consisted of an Astroquartz face fabric and Nicalon face and rib fabrics, while the single ply fabric segment was Nicalon. Further development will be required. The success of fabricating this assembly indicates that this concept may be feasible for certain types of space insulation requirements. The procedures developed for weaving the ICAS, joining the gores, and coating certain areas of the fabrics are presented.

  6. Energy Conversion Advanced Heat Transport Loop and Power Cycle

    SciTech Connect

    Oh, C. H.

    2006-08-01

    The Department of Energy and the Idaho National Laboratory are developing a Next Generation Nuclear Plant (NGNP) to serve as a demonstration of state-of-the-art nuclear technology. The purpose of the demonstration is two fold 1) efficient low cost energy generation and 2) hydrogen production. Although a next generation plant could be developed as a single-purpose facility, early designs are expected to be dual-purpose. While hydrogen production and advanced energy cycles are still in its early stages of development, research towards coupling a high temperature reactor, electrical generation and hydrogen production is under way. Many aspects of the NGNP must be researched and developed in order to make recommendations on the final design of the plant. Parameters such as working conditions, cycle components, working fluids, and power conversion unit configurations must be understood. Three configurations of the power conversion unit were demonstrated in this study. A three-shaft design with 3 turbines and 4 compressors, a combined cycle with a Brayton top cycle and a Rankine bottoming cycle, and a reheated cycle with 3 stages of reheat were investigated. An intermediate heat transport loop for transporting process heat to a High Temperature Steam Electrolysis (HTSE) hydrogen production plant was used. Helium, CO2, and an 80% nitrogen, 20% helium mixture (by weight) were studied to determine the best working fluid in terms cycle efficiency and development cost. In each of these configurations the relative component size were estimated for the different working fluids. The relative size of the turbomachinery was measured by comparing the power input/output of the component. For heat exchangers the volume was computed and compared. Parametric studies away from the baseline values of the three-shaft and combined cycles were performed to determine the effect of varying conditions in the cycle. This gives some insight into the sensitivity of these cycles to various

  7. Moon-Based Advanced Reusable Transportation Architecture: The MARTA Project

    NASA Astrophysics Data System (ADS)

    Alexander, R.; Bechtel, R.; Chen, T.; Cormier, T.; Kalaver, S.; Kirtas, M.; Lewe, J.-H.; Marcus, L.; Marshall, D.; Medlin, M.; McIntire, J.; Nelson, D.; Remolina, D.; Scott, A.; Weglian, J.; Olds, J.

    2000-01-01

    The Moon-based Advanced Reusable Transportation Architecture (MARTA) Project conducted an in-depth investigation of possible Low Earth Orbit (LEO) to lunar surface transportation systems capable of sending both astronauts and large masses of cargo to the Moon and back. This investigation was conducted from the perspective of a private company operating the transportation system for a profit. The goal of this company was to provide an Internal Rate of Return (IRR) of 25% to its shareholders. The technical aspect of the study began with a wide open design space that included nuclear rockets and tether systems as possible propulsion systems. Based on technical, political, and business considerations, the architecture was quickly narrowed down to a traditional chemical rocket using liquid oxygen and liquid hydrogen. However, three additional technologies were identified for further investigation: aerobraking, in-situ resource utilization (ISRU), and a mass driver on the lunar surface. These three technologies were identified because they reduce the mass of propellant used. Operational costs are the largest expense with propellant cost the largest contributor. ISRU, the production of materials using resources on the Moon, was considered because an Earth to Orbit (ETO) launch cost of 1600 per kilogram made taking propellant from the Earth's surface an expensive proposition. The use of an aerobrake to circularize the orbit of a vehicle coming from the Moon towards Earth eliminated 3, 100 meters per second of velocity change (Delta V), eliminating almost 30% of the 11,200 m/s required for one complete round trip. The use of a mass driver on the lunar surface, in conjunction with an ISRU production facility, would reduce the amount of propellant required by eliminating using propellant to take additional propellant from the lunar surface to Low Lunar Orbit (LLO). However, developing and operating such a system required further study to identify if it was cost effective. The

  8. Advanced transportation system study: Manned launch vehicle concepts for two way transportation system payloads to LEO

    NASA Technical Reports Server (NTRS)

    Duffy, James B.

    1993-01-01

    The purpose of the Advanced Transportation System Study (ATSS) task area 1 study effort is to examine manned launch vehicle booster concepts and two-way cargo transfer and return vehicle concepts to determine which of the many proposed concepts best meets NASA's needs for two-way transportation to low earth orbit. The study identified specific configurations of the normally unmanned, expendable launch vehicles (such as the National Launch System family) necessary to fly manned payloads. These launch vehicle configurations were then analyzed to determine the integrated booster/spacecraft performance, operations, reliability, and cost characteristics for the payload delivery and return mission. Design impacts to the expendable launch vehicles which would be required to perform the manned payload delivery mission were also identified. These impacts included the implications of applying NASA's man-rating requirements, as well as any mission or payload unique impacts. The booster concepts evaluated included the National Launch System (NLS) family of expendable vehicles and several variations of the NLS reference configurations to deliver larger manned payload concepts (such as the crew logistics vehicle (CLV) proposed by NASA JSC). Advanced, clean sheet concepts such as an F-1A engine derived liquid rocket booster (LRB), the single stage to orbit rocket, and a NASP-derived aerospace plane were also included in the study effort. Existing expendable launch vehicles such as the Titan 4, Ariane 5, Energia, and Proton were also examined. Although several manned payload concepts were considered in the analyses, the reference manned payload was the NASA Langley Research Center's HL-20 version of the personnel launch system (PLS). A scaled up version of the PLS for combined crew/cargo delivery capability, the HL-42 configuration, was also included in the analyses of cargo transfer and return vehicle (CTRV) booster concepts. In addition to strictly manned payloads, two-way cargo

  9. Advanced transportation system study: Manned launch vehicle concepts for two way transportation system payloads to LEO

    NASA Astrophysics Data System (ADS)

    Duffy, James B.

    1993-12-01

    The purpose of the Advanced Transportation System Study (ATSS) task area 1 study effort is to examine manned launch vehicle booster concepts and two-way cargo transfer and return vehicle concepts to determine which of the many proposed concepts best meets NASA's needs for two-way transportation to low earth orbit. The study identified specific configurations of the normally unmanned, expendable launch vehicles (such as the National Launch System family) necessary to fly manned payloads. These launch vehicle configurations were then analyzed to determine the integrated booster/spacecraft performance, operations, reliability, and cost characteristics for the payload delivery and return mission. Design impacts to the expendable launch vehicles which would be required to perform the manned payload delivery mission were also identified. These impacts included the implications of applying NASA's man-rating requirements, as well as any mission or payload unique impacts. The booster concepts evaluated included the National Launch System (NLS) family of expendable vehicles and several variations of the NLS reference configurations to deliver larger manned payload concepts (such as the crew logistics vehicle (CLV) proposed by NASA JSC). Advanced, clean sheet concepts such as an F-1A engine derived liquid rocket booster (LRB), the single stage to orbit rocket, and a NASP-derived aerospace plane were also included in the study effort. Existing expendable launch vehicles such as the Titan 4, Ariane 5, Energia, and Proton were also examined. Although several manned payload concepts were considered in the analyses, the reference manned payload was the NASA Langley Research Center's HL-20 version of the personnel launch system (PLS). A scaled up version of the PLS for combined crew/cargo delivery capability, the HL-42 configuration, was also included in the analyses of cargo transfer and return vehicle (CTRV) booster concepts. In addition to strictly manned payloads, two-way cargo

  10. Partnership and the Revitalization of Aviation: A Study of the Advanced General Aviation Transport Experiments Program, 1994-2001

    NASA Technical Reports Server (NTRS)

    Metz, Nanette Scarpellini

    2002-01-01

    As the Advanced General Aviation Transport Experiments (AGATE) program completes its eight-year plan, the outcomes and industry effects reveal its successes and problems. AGATE engaged several different types of institutions, including federal agencies, business and industry, universities, and non-profit organizations. By examining the perceptions of those intimately involved as well as periphery members, this study shows the powerful consequences of this type of combination both now and in the future. The problems are a particularly useful illustration of the interworking of a jointly funded research and development initiative. By learning how these problems are addressed, the study reveals lessons that may be applied to future government-industry partnerships.

  11. Advanced public transportation systems deployment in the United States: Update, January 1999. Final report, July--December 1998

    SciTech Connect

    Casey, R.F.

    1999-01-01

    This report documents work performed under FTA`s Advanced Public Transportation Systems (APTS) Program, a program structured to undertake research and development of innovative applications of advanced navigation, information, and communication technologies that most benefit public transportation.

  12. Local Institutional Development and Organizational Change for Advancing Sustainable Urban Water Futures

    NASA Astrophysics Data System (ADS)

    Brown, Rebekah R.

    2008-02-01

    This paper presents the local institutional and organizational development insights from a five-year ongoing interdisciplinary research project focused on advancing the implementation of sustainable urban water management. While it is broadly acknowledged that the inertia associated with administrative systems is possibly the most significant obstacle to advancing sustainable urban water management, contemporary research still largely prioritizes investigations at the technological level. This research is explicitly concerned with critically informing the design of methodologies for mobilizing and overcoming the administrative inertia of traditional urban water management practice. The results of fourteen in-depth case studies of local government organizations across Metropolitan Sydney primarily reveal that (i) the political institutionalization of environmental concern and (ii) the commitment to local leadership and organizational learning are key corporate attributes for enabling sustainable management. A typology of five organizational development phases has been proposed as both a heuristic and capacity benchmarking tool for urban water strategists, policy makers, and decision makers that are focused on improving the level of local implementation of sustainable urban water management activity. While this investigation has focused on local government, these findings do provide guideposts for assessing the development needs of future capacity building programs across a range of different institutional contexts.

  13. Local institutional development and organizational change for advancing sustainable urban water futures.

    PubMed

    Brown, Rebekah R

    2008-02-01

    This paper presents the local institutional and organizational development insights from a five-year ongoing interdisciplinary research project focused on advancing the implementation of sustainable urban water management. While it is broadly acknowledged that the inertia associated with administrative systems is possibly the most significant obstacle to advancing sustainable urban water management, contemporary research still largely prioritizes investigations at the technological level. This research is explicitly concerned with critically informing the design of methodologies for mobilizing and overcoming the administrative inertia of traditional urban water management practice. The results of fourteen in-depth case studies of local government organizations across Metropolitan Sydney primarily reveal that (i) the political institutionalization of environmental concern and (ii) the commitment to local leadership and organizational learning are key corporate attributes for enabling sustainable management. A typology of five organizational development phases has been proposed as both a heuristic and capacity benchmarking tool for urban water strategists, policy makers, and decision makers that are focused on improving the level of local implementation of sustainable urban water management activity. While this investigation has focused on local government, these findings do provide guideposts for assessing the development needs of future capacity building programs across a range of different institutional contexts.

  14. Which factors influence students' selection of advanced graduate programs? One institution's experience.

    PubMed

    Saeed, Sophia; Jimenez, Monik; Howell, Howard; Karimbux, Nadeem; Sukotjo, Cortino

    2008-06-01

    The reasons that students choose certain specialties may be integral to the quality of specialty programs and the future of those specialties. The Harvard School of Dental Medicine (HSDM) has a high percentage (87.6 percent) of students who enroll in postgraduate programs. The goals of this study were to establish a baseline of factors that affect postgraduate program selection at HSDM and to determine if there was a significant difference in factor selection by gender, relationship status, graduation year, or choice to specialize versus choice to pursue advanced training in general dentistry. As a pilot study, we asked HSDM graduates from the classes of 2005 to 2007 to rank the importance of forty-two factors in selecting a field of dentistry and a particular program or institution within a specialty. Overall, students felt that intellectual content, challenging diagnostic problems, and possessing a special skill or talent unique to a specialty were the most important factors in choosing a field of dentistry. Influence of family members in dentistry was ranked as least important. In choice of a certain program or institution within a given field, clinical training and philosophy of training were ranked most highly. Students felt that the opportunity to moonlight was least important. Significant differences (p<0.05) were found regarding gender, relationship status, and students who chose to specialize versus those pursuing advanced general dentistry training. No significant differences were found among the students in different graduating classes.

  15. Human factors of advanced technology (glass cockpit) transport aircraft

    NASA Technical Reports Server (NTRS)

    Wiener, Earl L.

    1989-01-01

    A three-year study of airline crews at two U.S. airlines who were flying an advanced technology aircraft, the Boeing 757 is discussed. The opinions and experiences of these pilots as they view the advanced, automated features of this aircraft, and contrast them with previous models they have flown are discussed. Training for advanced automation; (2) cockpit errors and error reduction; (3) management of cockpit workload; and (4) general attitudes toward cockpit automation are emphasized. The limitations of the air traffic control (ATC) system on the ability to utilize the advanced features of the new aircraft are discussed. In general the pilots are enthusiastic about flying an advanced technology aircraft, but they express mixed feelings about the impact of automation on workload, crew errors, and ability to manage the flight.

  16. Advanced transportation system study: Manned launch vehicle concepts for two way transportation system payloads to LEO. Program cost estimates document

    NASA Technical Reports Server (NTRS)

    Duffy, James B.

    1993-01-01

    This report describes Rockwell International's cost analysis results of manned launch vehicle concepts for two way transportation system payloads to low earth orbit during the basic and option 1 period of performance for contract NAS8-39207, advanced transportation system studies. Vehicles analyzed include the space shuttle, personnel launch system (PLS) with advanced launch system (ALS) and national launch system (NLS) boosters, foreign launch vehicles, NLS-2 derived launch vehicles, liquid rocket booster (LRB) derived launch vehicle, and cargo transfer and return vehicle (CTRV).

  17. Summary of the FY 2005 Batteries for Advanced Transportation Technologies (BATT) research program annual review

    SciTech Connect

    None, None

    2005-08-01

    This document presents a summary of the evaluation and comments provided by the review panel for the FY 2005 Department of Energy (DOE) Batteries for Advanced Transportation Technologies (BATT) program annual review.

  18. Development and Analysis of Advanced High-Temperature Technology for Nuclear Heat Transport and Power Conversion

    SciTech Connect

    Per F. Peterson

    2010-03-01

    This project by the Thermal Hydraulics Research Laboratory at U.C. Berkeley Studied advanced high-temperature heat transport and power conversion technology, in support of the Nuclear Hydrogen Initiative and Generation IV.

  19. Hazard alerting and situational awareness in advanced air transport cockpits

    NASA Technical Reports Server (NTRS)

    Hansman, R. John; Wanke, Craig; Kuchar, James; Mykityshyn, Mark; Hahn, Edward; Midkiff, Alan

    1993-01-01

    Advances in avionics and display technology have significantly changed the cockpit environment in current 'glass cockpit' aircraft. Recent developments in display technology, on-board processing, data storage, and datalinked communications are likely to further alter the environment in second and third generation 'glass cockpit' aircraft. The interaction of advanced cockpit technology with human cognitive performance has been a major area of activity within the MIT Aeronautical Systems Laboratory. This paper presents an overview of the MIT Advanced Cockpit Simulation Facility. Several recent research projects are briefly reviewed and the most important results are summarized.

  20. Study of the application of advanced technologies to long range transport aircraft. Volume 2: Advanced technology program recommendations

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The benefits of the application of advanced technology to future transport aircraft were investigated. The noise reduction goals established by the CARD (Civil Aviation Research and Development) study for the 1981-1985 time period can be satisfied. Reduced terminal area and airway congestion can result from use of advanced on-board systems and operating procedures. The use of advanced structural design concepts can result in greatly reduced gross weight and improved operating economics. The full potential of these benefits can be realized in a 1985 airplane by implementing a research and development program that is funded to an average level of approximately $55 million per year over a ten year period.

  1. Summary status of advanced water electrolysis and hydrogen storage/transport R and D

    SciTech Connect

    Mezzina, A.

    1984-04-01

    Major projects within the framework of the U.S. DOE Chemical/Hydrogen Energy Systems Program are described. Goals, accomplishments and status of investigations into advanced water electrolysis and hydrogen storage/transport are summarized. Electrolytic hydrogen production systems include: SPE electrolyzers; static feed water electrolysis; high temperature electrolysis; and other advanced concepts. Hydrogen transport studies have emphasized the characterization of hydrogen embrittlement effects on conventional natural gas pipeline steels.

  2. WAATS: A computer program for Weights Analysis of Advanced Transportation Systems

    NASA Technical Reports Server (NTRS)

    Glatt, C. R.

    1974-01-01

    A historical weight estimating technique for advanced transportation systems is presented. The classical approach to weight estimation is discussed and sufficient data is presented to estimate weights for a large spectrum of flight vehicles including horizontal and vertical takeoff aircraft, boosters and reentry vehicles. A computer program, WAATS (Weights Analysis for Advanced Transportation Systems) embracing the techniques discussed has been written and user instructions are presented. The program was developed for use in the ODIN (Optimal Design Integration System) system.

  3. Advances in Space Transportation Technology Toward the NASA Goals

    NASA Technical Reports Server (NTRS)

    Lyles, Garry M.

    2000-01-01

    disassembly and inspections required for the Space Shuttle's subsystems, the next generation vehicle's on-board health monitoring systems will could tell the ground crews which systems need replacement before landing. In twenty-five years, vehicles will be re-flown within one with crews numbering less than one hundred. Fully automated ground processing systems must require only a handful of personnel to launch the vehicle. Due to the increased intelligence of on-board systems, only cursory walk-around inspections would be required between flights An assessment of the progress in breakthrough technologies toward these goals by the NASA Advanced Space Transportation Program is presented. These breakthrough technologies include combined rocket and air breathing propulsion, high strength lightweight structures, high temperature materials, vehicle health management, and flight operations.

  4. How SmartWay Advances Sustainable Transportation Supply Chains

    EPA Pesticide Factsheets

    This page provides information on how the SmartWay program has achieved reductions in freight transportation-related greenhouse gas emissions and how it will continue to do so with its Vision 2020 strategies.

  5. Sun-downing and integration for the advancement of science and therapeutics: the National Institute on Substance Use Disorders (NISUD).

    PubMed

    Grabowski, John

    2010-12-01

    The National Institutes of Health (NIH) is the most prominent funding source for scientific research in the world. It is also a complex and diverse organization, having multiple institutes, centers and offices. NIH emphasizes the need for innovation and collaboration in research to discover critical knowledge, enhance health and prevent disease. Advancement in science requires not only sophisticated methods, but also logical organization. Here, an overview of ‘behavioral research’ (writ large) at NIH is presented, focusing upon the common trinity of ‘alcohol, tobacco/nicotine and other drugs’ and programmatic overlap across entities. Consideration is also given to the origins of institutes and their historical movement across organizational boundaries. Specific issues, concerns and advantages of integration of the National Institute on Drug Abuse and National Institute on Alcoholism and Alcohol Abuse are addressed. It is concluded that advances in understanding, treating and preventing substance use disorders would best be served by (1)review and integration of all related research throughout NIH, (2) logical placement of leadership for this activity in a single institute, here entitled the National Institute on Substance Use Disorders, and (3) close collaboration of this institute with its complementary partner, the National Institute on Mental Health. Thus, NIH can establish an organizational structure and collaborations reflecting the realities of the scientific and disease/health domains. This would make a prominent statement to the world scientific and health communities regarding NIH recognition of the need for innovation (scientific and organizational) and focus upon these myriad interrelated and costly problems.

  6. Technology requirements for advanced earth orbital transportation systems. Volume 2: Summary report

    NASA Technical Reports Server (NTRS)

    Hepler, A. K.; Bangsund, E. L.

    1978-01-01

    The results of efforts to identify the technology requirements for advanced earth orbital transportation systems are reported. Topics discussed include: (1) design and definition of performance potential of vehicle systems, (2) advanced technology assessment, and (3) extended performance. It is concluded that the horizontal take-off concept is the most feasible system considered.

  7. Assessment of the application of advanced technologies to subsonic CTOL transport aircraft

    NASA Technical Reports Server (NTRS)

    Graef, J. D.; Sallee, G. P.; Verges, J. T.

    1974-01-01

    Design studies of the application of advanced technologies to future transport aircraft were conducted. These studies were reviewed from the perspective of an air carrier. A fundamental study of the elements of airplane operating cost was performed, and the advanced technologies were ranked in order of potential profit impact. Recommendations for future study areas are given.

  8. Graphite/Polyimide Composites. [conference on Composites for Advanced Space Transportation Systems

    NASA Technical Reports Server (NTRS)

    Dexter, H. B. (Editor); Davis, J. G., Jr. (Editor)

    1979-01-01

    Technology developed under the Composites for Advanced Space Transportation System Project is reported. Specific topics covered include fabrication, adhesives, test methods, structural integrity, design and analysis, advanced technology developments, high temperature polymer research, and the state of the art of graphite/polyimide composites.

  9. An airline study of advanced technology requirements for advanced high speed commercial transport engines. 1: Engine design study assessment

    NASA Technical Reports Server (NTRS)

    Sallee, G. P.

    1973-01-01

    The advanced technology requirements for an advanced high speed commercial tranport engine are presented. The results of the phase 1 study effort cover the following areas: (1) statement of an airline's major objectives for future transport engines, (2) airline's method of evaluating engine proposals, (3) description of an optimum engine for a long range subsonic commercial transport including installation and critical design features, (4) discussion of engine performance problems and experience with performance degradation, (5) trends in engine and pod prices with increasing technology and objectives for the future, (6) discussion of the research objectives for composites, reversers, advanced components, engine control systems, and devices to reduce the impact of engine stall, and (7) discussion of the airline objectives for noise and pollution reduction.

  10. Recent advances in arsenic bioavailability, transport, and speciation in rice.

    PubMed

    Wang, Xin; Peng, Bo; Tan, Changyin; Ma, Lena; Rathinasabapathi, Bala

    2015-04-01

    Widespread arsenic (As) contamination in paddy rice (Oryza sativa) from both geologic and anthropogenic origins is an increasing concern globally. Substantial efforts have been made to elucidate As transformation and uptake processes in rhizosphere and metabolism in rice plant, which provides an essential foundation for the development of mitigation strategies. However, a range of crucial mechanisms from As mobilization in rhizosphere to transport to grains remain poorly understood. To provide new insight into the underlying mechanisms of As accumulation in rice, a range of new perspectives on As bioavailability, transport pathways, and in situ speciation are reviewed here. Specifically, the prominent effects of water regime, Fe plaque, and biochar on As mobilization in rice rhizosphere are discussed critically. An updated understanding of arsenite (AsIII) and methylated As transport from root to vascular bundle and grain is integrated and discussed in detail. Special attention is given to As speciation and distribution in rice grain with potential coping strategies being provided and discussed. Future research priorities are also identified. The new insight into As bioavailability, transport and speciation in rice would lead to a better understanding of As contamination in rice. They would also provide useful strategies from agronomic measures to genetic engineering for more effective restriction of As transport and accumulation in food chain.

  11. Chemotherapy for elderly patients with advanced cancer: A pilot study in Institute of Oncology Bucharest

    PubMed Central

    Grigorescu, Alexandru C.

    2015-01-01

    Objectives First objective was better understanding of the indications of chemotherapy in elderly with advanced cancer, tolerability and toxicity of chemotherapy in this age group. The second objective was to define current practice in chemotherapy for elderly people with advanced cancer for a selected group of patients treated in Institute of Oncology Bucharest (IOB). Materials and Methods The study makes a clinical analysis of medical records of 27 patients from the archive of Institute of Oncology Bucharest treated by the same doctor. Patients were selected according to: age ≥ 65 years, ECOG performance status 0–1, normal blood counts and blood biochemistry, histological confirmation of the diagnosis of cancer, patients should received at least 3 cycles of chemotherapy. We extract characteristics of the patients to see if they were a homogeneous group of patients and to compare them with data from the literature. Overall survival was calculated by the Kaplan Meyer curve. Results 295 patients more then 65 years were treated in our site in 2 years 2011, 2012. 93 patients received chemotherapy and only 27 patients were enrolled in this study following inclusion criteria. Common sites of cancer were lung and breast. The most used cytostatics for lung cancer was gemcitabine and carboplatine and cyclophosphamide, metotrexat and 5 fluorouracil for breast cancer. Toxicity was mild with the prevalence of hematologic toxicity. Overall survival without taking into account the type of cancer was 27.7 month. Conclusions For selected patients, chemotherapy was well tolerated and appears to prolong survival regardless of the location of cancer. The relatively small number of elderly patients who received chemotherapy is probably due to lack of compliance to treatment, the increased number of co-morbidities and evaluation of performance status only by the ECOG index known not to be good enough to establish the indication of chemotherapy. PMID:27847881

  12. Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations.

    PubMed

    Alsharif, Naser Z; Dakkuri, Adnan; Abrons, Jeanine P; Williams, Dennis; Ombengi, David N; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O'Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

    2016-04-25

    International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education.

  13. Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations

    PubMed Central

    Dakkuri, Adnan; Abrons, Jeanine P.; Williams, Dennis; Ombengi, David N.; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O’Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

    2016-01-01

    International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education. PMID:27170809

  14. Conformal Radiotherapy in the Treatment of Advanced Juvenile Nasopharyngeal Angiofibroma With Intracranial Extension: An Institutional Experience

    SciTech Connect

    Chakraborty, Santam; Ghoshal, Sushmita; Patil, Vijay Maruti; Oinam, Arun Singh; Sharma, Suresh C.

    2011-08-01

    Purpose: To describe the results of conformal radiotherapy in advanced juvenile nasopharyngeal angiofibroma in a tertiary care institution. Methods and Materials: Retrospective chart review was conducted for 8 patients treated with conformal radiotherapy between 2006 and 2009. The median follow-up was 17 months. All patients had Stage IIIB disease with intracranial extension. Radiotherapy was considered as treatment because patients were deemed inoperable owing to extensive intracranial/intraorbital extension or proximity to optic nerve. All but 1 patient were treated with intensity-modulated radiotherapy using seven coplanar fields. Median (range) dose prescribed was 39.6 (30-46) Gy. Actuarial analysis of local control and descriptive analysis of toxicity profile was conducted. Results: Despite the large and complex target volume (median planning target volume, 292 cm{sup 3}), intensity-modulated radiotherapy achieved conformal dose distributions (median van't Reit index, 0.66). Significant sparing of the surrounding organs at risk was obtained. No significant Grade 3/4 toxicities were experienced during or after treatment. Actual local control at 2 years was 87.5%. One patient died 1 month after radiotherapy secondary to massive epistaxis. The remaining 7 patients had progressive resolution of disease and were symptom-free at last follow-up. Persistent rhinitis was the only significant toxicity, seen in 1 patient. Conclusions: Conformal radiotherapy results in good local control with minimal acute and late side effects in juvenile nasopharyngeal angiofibromas, even in the presence of advanced disease.

  15. Advancing the understanding of plasma transport in mid-size stellarators

    NASA Astrophysics Data System (ADS)

    Hidalgo, Carlos; Talmadge, Joseph; Ramisch, Mirko; TJ-II, the; HXS; TJ-K Teams

    2017-01-01

    The tokamak and the stellarator are the two main candidate concepts for magnetically confining fusion plasmas. The flexibility of the mid-size stellarator devices together with their unique diagnostic capabilities make them ideally suited to study the relation between magnetic topology, electric fields and transport. This paper addresses advances in the understanding of plasma transport in mid-size stellarators with an emphasis on the physics of flows, transport control, impurity and particle transport and fast particles. The results described here emphasize an improved physics understanding of phenomena in stellarators that complements the empirical approach. Experiments in mid-size stellarators support the development of advanced plasma scenarios in Wendelstein 7-X (W7-X) and, in concert with better physics understanding in tokamaks, may ultimately lead to an advance in the prediction of burning plasma behaviour.

  16. Structural design of integral tankage for advanced space transportation systems

    NASA Technical Reports Server (NTRS)

    Macconochie, I. O.; Davis, R. B.; Lemessurier, R. W.

    1982-01-01

    Fully reusable launch vehicle concepts being studied for post-Shuttle era transports present major challenges for the structural design of large propellant tankage. The dominant structural elements are internal tankage for both cryogenic and non-cryogenic propellants which must operate in a broad range of thermal environments while meeting requirements for low weight and reusability. Several approaches to integral tank design are discussed and an analysis of a hot structure honeycomb sandwich tank for a circular body vehicle is presented.

  17. Manganese: Recent advances in understanding its transport and neurotoxicity

    SciTech Connect

    Aschner, Michael . E-mail: Michael.Aschner@vanderbilt.edu; Guilarte, Tomas R.; Schneider, Jay S.; Zheng Wei

    2007-06-01

    The present review is based on presentations from the meeting of the Society of Toxicology in San Diego, CA (March 2006). It addresses recent developments in the understanding of the transport of manganese (Mn) into the central nervous system (CNS), as well as brain imaging and neurocognitive studies in non-human primates aimed at improving our understanding of the mechanisms of Mn neurotoxicity. Finally, we discuss potential therapeutic modalities for treating Mn intoxication in humans.

  18. An airline study of advanced technology requirements for advanced high speed commercial transport engines. 2: Engine preliminary design assessment

    NASA Technical Reports Server (NTRS)

    Sallee, G. P.

    1973-01-01

    The advanced technology requirements for an advanced high speed commercial transport engine are presented. The results of the phase 2 study effort cover the following areas: (1) general review of preliminary engine designs suggested for a future aircraft, (2) presentation of a long range view of airline propulsion system objectives and the research programs in noise, pollution, and design which must be undertaken to achieve the goals presented, (3) review of the impact of propulsion system unreliability and unscheduled maintenance on cost of operation, (4) discussion of the reliability and maintainability requirements and guarantees for future engines.

  19. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false May an advance of funds be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105 Public... transporting HHG and temporary storage? An advance of funds may be authorized when the transportation of...

  20. Acoustic charge transport technology investigation for advanced development transponder

    NASA Technical Reports Server (NTRS)

    Kayalar, S.

    1993-01-01

    Acoustic charge transport (ACT) technology has provided a basis for a new family of analog signal processors, including a programmable transversal filter (PTF). Through monolithic integration of ACT delay lines with GaAs metal semiconductor field effect transistor (MESFET) digital memory and controllers, these devices significantly extend the performance of PTF's. This article introduces the basic operation of these devices and summarizes their present and future specifications. The production and testing of these devices indicate that this new technology is a promising one for future space applications.

  1. SBIR Advanced Technologies in Aviation and Air Transportation System 2016

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung D.; Steele, Gynelle C.; Kaszeta, Richard W.; Gold, Calman; Corke, Thomas C.; McGowan, Ryan; Matlis, Eric; Eichenlaub, Jesse; Davis, Joshua T.; Shah, Parthiv N.

    2017-01-01

    This report is intended to provide a broad knowledge of various topics associated with NASA's Aeronautics Research Mission Directorate (ARMD), with particular interest on the NASA SBIR contracts awarded from 2011-2012 executed by small companies. The content of this report focuses on the high-quality, cutting-edge research that will lead to revolutionary concepts, technologies, and capabilities that enable radical change to both the airspace system and the aircraft that fly within it, facilitating a safer, more environmentally friendly, and more efficient air transportation system.

  2. Advanced transportation concept for round-trip space travel

    NASA Technical Reports Server (NTRS)

    Yen, Chen-Wan L.

    1988-01-01

    A departure from the conventional concept of round-trip space travel is introduced. It is shown that a substantial reduction in the initial load required of the Shuttle or other launch vehicle can be achieved by staging the ascent orbit and leaving fuel for the return trip at each stage of the orbit. Examples of round trips from a low-inclination LEO to a high-inclination LEO and from an LEO to a GEO are used to show the merits of the new concept. Potential problem areas and research needed for the development of an efficient space transportation network are discussed.

  3. Advances in Neutral Transport Modeling with DEGAS 2

    NASA Astrophysics Data System (ADS)

    Karney, C. F. F.; Stotler, D. P.; Braams, B. J.; Rognlien, T. D.; Rensink, M. E.; Kanzleiter, R. J.

    1997-11-01

    With the next major release of the DEGAS 2 Monte Carlo neutral transport code(D. Stotler and C. Karney, Contrib. Plasma Phys.) 34, 392 (1994)., the user will have access to a flexible scoring capability; a standard set of neutral and background plasma scores will be included by default. A separate set of scoring arrays will be used for time-dependent coupling to fluid plasma codes. Implicit techniques are being investigated as a way to increase the time-step relative to the explicit approach(D. Reiter, Chr. May, D. Coster, and R. Schneider, J. Nucl. Mater.) 220-222, 987 (1995).. Satisfactory execution times will be achieved by running the coupled system on massively parallel computers. Handling of high neutral density regions will be improved via a hybrid fluid-Monte Carlo model of the neutral transport. The DG grid generation and surface data input facility is being adapted for use with DEGAS 2 to provide an easy way for the user to transform equilibrium data and CAD hardware files into DEGAS 2 geometry input.

  4. Advanced Hall Electric Propulsion for Future In-space Transportation

    NASA Technical Reports Server (NTRS)

    Oleson, Steven R.; Sankovic, John M.

    2001-01-01

    The Hall thruster is an electric propulsion device used for multiple in-space applications including orbit raising, on-orbit maneuvers, and de-orbit functions. These in-space propulsion functions are currently performed by toxic hydrazine monopropellant or hydrazine derivative/nitrogen tetroxide bi-propellant thrusters. The Hall thruster operates nominally in the 1500 sec specific impulse regime. It provides greater thrust to power than conventional gridded ion engines, thus reducing trip times and operational life when compared to that technology in Earth orbit applications. The technology in the far term, by adding a second acceleration stage, has shown promise of providing over 4000s Isp, the regime of the gridded ion engine and necessary for deep space applications. The Hall thruster system consists of three parts, the thruster, the power processor, and the propellant system. The technology is operational and commercially available at the 1.5 kW power level and 5 kW application is underway. NASA is looking toward 10 kW and eventually 50 kW-class engines for ambitious space transportation applications. The former allows launch vehicle step-down for GEO missions and demanding planetary missions such as Europa Lander, while the latter allows quick all-electric propulsion LEO to GEO transfers and non-nuclear transportation human Mars missions.

  5. ADVANCES IN COMPREHENSIVE GYROKINETIC SIMULATIONS OF TRANSPORT IN TOKAMAKS

    SciTech Connect

    WALTZ,R.E; CANDY,J; HINTON,F.L; ESTRADA-MILA,C; KINSEY,J.E

    2004-10-01

    A continuum global gyrokinetic code GYRO has been developed to comprehensively simulate core turbulent transport in actual experimental profiles and enable direct quantitative comparisons to the experimental transport flows. GYRO not only treats the now standard ion temperature gradient (ITG) mode turbulence, but also treats trapped and passing electrons with collisions and finite {beta}, equilibrium ExB shear stabilization, and all in real tokamak geometry. Most importantly the code operates at finite relative gyroradius ({rho}{sub *}) so as to treat the profile shear stabilization and nonlocal effects which can break gyroBohm scaling. The code operates in either a cyclic flux-tube limit (which allows only gyroBohm scaling) or globally with physical profile variation. Bohm scaling of DIII-D L-mode has been simulated with power flows matching experiment within error bars on the ion temperature gradient. Mechanisms for broken gyroBohm scaling, neoclassical ion flows embedded in turbulence, turbulent dynamos and profile corrugations, are illustrated.

  6. ADVANCES IN COMPREHENSIVE GYROKINETIC SIMULATIONS OF TRANSPORT IN TOKAMAKS

    SciTech Connect

    WALTZ RE; CANDY J; HINTON FL; ESTRADA-MILA C; KINSEY JE

    2004-10-01

    A continuum global gyrokinetic code GYRO has been developed to comprehensively simulate core turbulent transport in actual experimental profiles and enable direct quantitative comparisons to the experimental transport flows. GYRO not only treats the now standard ion temperature gradient (ITG) mode turbulence, but also treats trapped and passing electrons with collisions and finite {beta}, equilibrium ExB shear stabilization, and all in real tokamak geometry. Most importantly the code operates at finite relative gyroradius ({rho}{sub *}) so as to treat the profile shear stabilization and nonlocal effects which can break gyroBohm scaling. The code operates in either a cyclic flux-tube limit (which allows only gyroBohm scaling) or a globally with physical profile variation. Rohm scaling of DIII-D L-mode has been simulated with power flows matching experiment within error bars on the ion temperature gradient. Mechanisms for broken gyroBohm scaling, neoclassical ion flows embedded in turbulence, turbulent dynamos and profile corrugations, plasma pinches and impurity flow, and simulations at fixed flow rather than fixed gradient are illustrated and discussed.

  7. Research Institute for Advanced Computer Science: Annual Report October 1998 through September 1999

    NASA Technical Reports Server (NTRS)

    Leiner, Barry M.; Gross, Anthony R. (Technical Monitor)

    1999-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center (ARC). It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. ARC has been designated NASA's Center of Excellence in Information Technology. In this capacity, ARC is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA ARC and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to

  8. Finding a Balance: Fifteen Institutional Case Studies on the Relationship between Part-Time Work and Advanced Level Study. Report.

    ERIC Educational Resources Information Center

    Hodgson, Ann, Ed.; Spours, Ken, Ed.

    This document presents and discusses case studies that examined the relationship between part-time employment and advanced level study at 15 schools in Essex, England. "Foreword" (David Jones) provides a brief overview of the project. "Finding a Balance--Fifteen Institutional Case Studies on the Relationship between Part-time Work…

  9. The Institute for the Advancement of Social Work Research: Working to Increase Our Practice and Policy Evidence Base

    ERIC Educational Resources Information Center

    Zlotnik, Joan Levy; Solt, Barbara E.

    2006-01-01

    This invitational update on the Institute for the Advancement of Social Work Research (IASWR) provides an overview of the work and progress toward strengthening the evidence base for social work practice and policy through research. The article includes information regarding IASWR work with its supporting social work organizations to provide a…

  10. Support for NATO Advanced Study Institute on molecular ecology of aquatic microbes, August 28--September 9, 1994. Final report

    SciTech Connect

    Joint, I.

    1995-06-16

    This is a summary paper for a NATO Advanced Study Institute sponsored meeting entitled `The Molecular Ecology of Aquatic Microbes` held in Luccia, Italy from August 28 to September 9, 1994. A full reference book for the proceedings is to be published later.

  11. Advanced composite aileron for L-1011 transport aircraft: Aileron manufacture

    NASA Technical Reports Server (NTRS)

    Dunning, E. G.; Cobbs, W. L.; Legg, R. L.

    1981-01-01

    The fabrication activities of the Advanced Composite Aileron (ACA) program are discussed. These activities included detail fabrication, manufacturing development, assembly, repair and quality assurance. Five ship sets of ailerons were manufactured. The detail fabrication effort of ribs, spar and covers was accomplished on male tools to a common cure cycle. Graphite epoxy tape and fabric and syntactic epoxy materials were utilized in the fabrication. The ribs and spar were net cured and required no post cure trim. Material inconsistencies resulted in manufacturing development of the front spar during the production effort. The assembly effort was accomplished in subassembly and assembly fixtures. The manual drilling system utilized a dagger type drill in a hydraulic feed control hand drill. Coupon testing for each detail was done.

  12. Advanced dosimetry systems for the space transport and space station

    NASA Technical Reports Server (NTRS)

    Wailly, L. F.; Schneider, M. F.; Clark, B. C.

    1972-01-01

    Advanced dosimetry system concepts are described that will provide automated and instantaneous measurement of dose and particle spectra. Systems are proposed for measuring dose rate from cosmic radiation background to greater than 3600 rads/hr. Charged particle spectrometers, both internal and external to the spacecraft, are described for determining mixed field energy spectra and particle fluxes for both real time onboard and ground-based computer evaluation of the radiation hazard. Automated passive dosimetry systems consisting of thermoluminescent dosimeters and activation techniques are proposed for recording the dose levels for twelve or more crew members. This system will allow automatic onboard readout and data storage of the accumulated dose and can be transmitted to ground after readout or data records recovered with each crew rotation.

  13. Advanced composite aileron for L-1011 transport aircraft

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Design and evaluation of alternate concepts for the major subcomponents of the advanced composite aileron (ACA) was completed. From this array of subcomponents, aileron assemblies were formulated and evaluated. Based on these analyses a multirib assembly with graphite tape/syntactic core covers, a graphite tape front spar, and a graphite fabric rib was selected for development. A weight savings of 29.1 percent (40.8 pounds per aileron) is predicted. Engineering cost analyses indicate that the production cost of the ACA will be 7.3 percent less than the current aluminum aileron. Fabrication, machining, and testing of the material evaluation specimens for the resin screening program was completed. The test results lead to the selection of Narmco 5208 resin for the ACA. Other activities completed include: the detailed design of the ACA, construction of a three dimensional finite element model for structural analysis, and formulation of detail plans for material verification and process development.

  14. Multiple Application Propfan Study (MAPS): Advanced tactical transport

    NASA Technical Reports Server (NTRS)

    Newton, F. C.; Liebeck, R. H.; Mitchell, G. H.; Mooiweer, A.; Platte, M. M.; Toogood, T. L.; Wright, R. A.

    1986-01-01

    This study was conducted to ascertain potential benefits of a propfan propulsion system application to a blended wing/body military tactical transport. Based on a design cruise Mach no. of 0.75 for the design mission, the results indicate a significant advantage in various figures of merit for the propfan over those of a comparable technology turbofan. Although the propfan has a 1.6 percent greater takeoff gross weight, its life cycle cost is 5.3 percent smaller, partly because of a 27 percent smaller specific fuel consumption. When employed on alternate missions, the propfan configuration offers significantly improved flexibility and capability: an increase in sea level penetration distance of more than 100 percent, or in time-on-station of 24 percent, or in deployment payload of 38 percent.

  15. Advances in NASA radiation transport research: 3DHZETRN

    NASA Astrophysics Data System (ADS)

    Wilson, John W.; Slaba, Tony C.; Badavi, Francis F.; Reddell, Brandon D.; Bahadori, Amir A.

    2014-07-01

    The computationally efficient HZETRN code has been used in recent trade studies for lunar and Martian exploration and is currently being used in the engineering development of the next generation of space vehicles, habitats, and extra vehicular activity equipment. Code development has been based on a progression of approximations first assuming all particles are produced in the initiator direction of incidence (straight-ahead) later improved by treating neutrons produced in the backward hemisphere as moving straight-back (bi-directional). A new version (3DHZETRN) capable of transporting High charge (Z) and Energy (HZE) and light ions (including neutrons) under space-like boundary conditions with enhanced neutron and light ion propagation in transverse directions is developed. Herein, new algorithms for light ion and neutron propagation with well defined convergence criteria in 3D objects is developed and tested against Monte Carlo simulations of 3D effects.

  16. Advances in the Understanding of Mammalian Copper Transporters12

    PubMed Central

    Wang, Yanfang; Hodgkinson, Victoria; Zhu, Sha; Weisman, Gary A.; Petris, Michael J.

    2011-01-01

    Copper (Cu) is an essential micronutrient. Its ability to exist in 2 oxidation states (Cu1+ and Cu2+) allows it to function as an enzymatic cofactor in hydrolytic, electron transfer, and oxygen utilization reactions. Cu transporters CTR1, ATP7A, and ATP7B play key roles in ensuring that adequate Cu is available for Cu-requiring processes and the prevention of excess Cu accumulation within cells. Two diseases of Cu metabolism, Menkes disease and Wilson disease, which are caused by mutations in ATP7A and ATP7B, respectively, exemplify the critical importance of regulating Cu balance in humans. Herein, we review recent studies of the biochemical and cell biological characteristics of CTR1, ATP7A, and ATP7B, as well as emerging roles for Cu in new areas of physiology. PMID:22332042

  17. Economic study of multipurpose advanced high-speed transport configurations

    NASA Technical Reports Server (NTRS)

    1979-01-01

    A nondimensional economic examination of a parametrically-derived set of supersonic transport aircraft was conducted. The measure of economic value was surcharged relative to subsonic airplane tourist-class yield. Ten airplanes were defined according to size, payload, and speed. The price, range capability, fuel burned, and block time were determined for each configuration, then operating costs and surcharges were calculated. The parameter with the most noticeable influence on nominal surcharge was found to be real (constant dollars) fuel price increase. A change in SST design Mach number from 2.4 to Mach 2.7 showed a very small surcharge advantage (on the order of 1 percent for the faster aircraft). Configuration design compromises required for an airplane to operate overland at supersonic speeds without causing sonic boom annoyance result in severe performance penalties and require high (more than 100 percent) surcharges.

  18. Advanced subsonic long-haul transport terminal area compatibility study. Volume 1: Compatibility assessment

    NASA Technical Reports Server (NTRS)

    1974-01-01

    An analysis was made to identify airplane research and technology necessary to ensure advanced transport aircraft the capability of accommodating forecast traffic without adverse impact on airport communities. Projections were made of the delay, noise, and emissions impact of future aircraft fleets on typical large urban airport. Design requirements, based on these projections, were developed for an advanced technology, long-haul, subsonic transport. A baseline aircraft was modified to fulfill the design requirements for terminal area compatibility. Technical and economic comparisons were made between these and other aircraft configured to support the study.

  19. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    SciTech Connect

    2010-01-01

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  20. NREL - Advanced Vehicles and Fuels Basics - Center for Transportation Technologies and Systems 2010

    ScienceCinema

    None

    2016-07-12

    We can improve the fuel economy of our cars, trucks, and buses by designing them to use the energy in fuels more efficiently. Researchers at the National Renewable Energy Laboratory (NREL) are helping the nation achieve these goals by developing transportation technologies like: advanced vehicle systems and components; alternative fuels; as well as fuel cells, hybrid electric, and plug-in hybrid vehicles. For a text version of this video visit http://www.nrel.gov/learning/advanced_vehicles_fuels.html

  1. Addressing the Need for Alternative Transportation Fuels: The Joint BioEnergy Institute

    SciTech Connect

    Blanch, Harvey; Adams, Paul; Andrews-Cramer, Katherine; Frommer, Wolf; Simmons, Blake; Keasling, Jay

    2008-01-18

    activity of enzymes used to deconstruct biomass, and the inhibitory effect of fuels and processing byproducts on organisms responsible for producing fuels from biomass monomers. The Joint BioEnergy Institute (JBEI) is a U.S. Department of Energy (DOE) Bioenergy Research Center that will address these roadblocks in biofuels production. JBEI draws on the expertise and capabilities of three national laboratories (Lawrence Berkeley National Laboratory (LBNL), Sandia National Laboratories (SNL), and Lawrence Livermore National Laboratory (LLNL)), two leading U.S. universities (University of California campuses at Berkeley (UCB) and Davis (UCD)), and a foundation (Carnegie Institute for Science, Stanford) to develop the scientific and technological base needed to convert the energy stored in lignocellulose into transportation fuels and commodity chemicals. Established scientists from the participating organizations are leading teams of researchers to solve the key scientific problems and develop the tools and infrastructure that will enable other researchers and companies to rapidly develop new biofuels and scale production to meet U.S. transportation needs and to develop and rapidly transition new technologies to the commercial sector. JBEI's biomass-to-biofuels research approach is based in three interrelated scientific divisions and a technologies division. The Feedstocks Division will develop improved plant energy crops to serve as the raw materials for biofuels. The Deconstruction Division will investigate the conversion of this lignocellulosic plant material to sugar and aromatics. The Fuels Synthesis Division will create microbes that can efficiently convert sugar and aromatics into ethanol and other biofuels. JBEI's cross-cutting Technologies Division will develop and optimize a set of enabling technologies including high-throughput, chipbased, and omics platforms; tools for synthetic biology; multi-scale imaging facilities; and integrated data analysis to support and

  2. Advanced public transportation systems: State of the art update `98. Final report, July-December 1997

    SciTech Connect

    Casey, R.F.; Labell, L.N.; LoVecchio, J.A.; Ow, R.S.; Royal, J.W.

    1998-01-01

    This report is the latest in a series of State-of-the-Art reports, the last of which was published in January 1996. It contains the results of an investigation of the extent of adoption of advanced technology in the provision of public transportation service in North America. It focused on some of the most innovative or comprehensive implementations, categorized under four types of service/technologies: Fleet Management, Traveler Information, Electronic Fare Payment, and Transportation Demand Management.

  3. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... STORAGE OF PROPERTY 7-TRANSPORTATION AND TEMPORARY STORAGE OF HOUSEHOLD GOODS AND PROFESSIONAL BOOKS... transporting HHG and temporary storage? An advance of funds may be authorized when the transportation of HHG... be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105...

  4. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... STORAGE OF PROPERTY 7-TRANSPORTATION AND TEMPORARY STORAGE OF HOUSEHOLD GOODS AND PROFESSIONAL BOOKS... transporting HHG and temporary storage? An advance of funds may be authorized when the transportation of HHG... be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105...

  5. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... STORAGE OF PROPERTY 7-TRANSPORTATION AND TEMPORARY STORAGE OF HOUSEHOLD GOODS AND PROFESSIONAL BOOKS... transporting HHG and temporary storage? An advance of funds may be authorized when the transportation of HHG... be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105...

  6. Advanced High-Temperature, High-Pressure Transport Reactor Gasification

    SciTech Connect

    Michael L. Swanson

    2005-08-30

    The transport reactor development unit (TRDU) was modified to accommodate oxygen-blown operation in support of a Vision 21-type energy plex that could produce power, chemicals, and fuel. These modifications consisted of changing the loop seal design from a J-leg to an L-valve configuration, thereby increasing the mixing zone length and residence time. In addition, the standpipe, dipleg, and L-valve diameters were increased to reduce slugging caused by bubble formation in the lightly fluidized sections of the solid return legs. A seal pot was added to the bottom of the dipleg so that the level of solids in the standpipe could be operated independently of the dipleg return leg. A separate coal feed nozzle was added that could inject the coal upward into the outlet of the mixing zone, thereby precluding any chance of the fresh coal feed back-mixing into the oxidizing zone of the mixing zone; however, difficulties with this coal feed configuration led to a switch back to the original downward configuration. Instrumentation to measure and control the flow of oxygen and steam to the burner and mix zone ports was added to allow the TRDU to be operated under full oxygen-blown conditions. In total, ten test campaigns have been conducted under enriched-air or full oxygen-blown conditions. During these tests, 1515 hours of coal feed with 660 hours of air-blown gasification and 720 hours of enriched-air or oxygen-blown coal gasification were completed under this particular contract. During these tests, approximately 366 hours of operation with Wyodak, 123 hours with Navajo sub-bituminous coal, 143 hours with Illinois No. 6, 106 hours with SUFCo, 110 hours with Prater Creek, 48 hours with Calumet, and 134 hours with a Pittsburgh No. 8 bituminous coal were completed. In addition, 331 hours of operation on low-rank coals such as North Dakota lignite, Australian brown coal, and a 90:10 wt% mixture of lignite and wood waste were completed. Also included in these test campaigns was

  7. Engineering and management experience at Texas A&M Transportation Institute

    NASA Astrophysics Data System (ADS)

    Chowdhury, Arif Tahjibul

    This manuscript presents the author's engineering and management experience during his internship in the Materials and Pavements (M&P) Division at the Texas A&M Transportation Institute (TTI), and is a record of study for the Doctor of Engineering at Texas A&M University. Through this internship, he met his established internship objectives of gaining technical knowledge as well as knowledge and skills in project management, organizational communication, and quality management of pavement condition data, and of attaining professional development. In meeting these objectives, the author describes the history, mission, and organizational structure of his workplace. He also presents his experience of developing and delivering a two-week training course on pavement design and construction in Kosovo. Participating in a number of professional development training courses and other activities prepared him for working as an engineering manager. These activities include Delta-T leadership training, an instructor development course, a time management and organizational skills course, and the M&P Division lecture series. Leadership and skills learned through the Delta-T program were beneficial for the employee as well as the employer. For the class project, the author and his teammates performed a study dealing with improving TTI's deliverables. The Delta-T team composed a report summarizing their efforts of examining the current state of TTI's project deliverables, the deliverables' shortcomings, and potential enhancements to expand the deliverables' appeal to additional types of potential users outside the traditional research community. The team also developed a prototype web-based model of deliverables and presented some implementation recommendations. Participating in the Texas Department of Transportation's (TxDOT's) pavement surface distress data collection program enabled the author to become familiar with pavement distress data quality management and thus attain the

  8. Strategic Institutional Change to Support Advancement of Women Scientists in the Academy: Lessons from a Study of ADVANCE-IT Projects

    NASA Astrophysics Data System (ADS)

    Laursen, S. L.; Austin, A. E.; Soto, M.; Martinez, D.

    2011-12-01

    While women's representation among undergraduate and graduate degree-earners has grown steadily in most science fields, progress at the faculty level has been slow to realize, especially in upper academic ranks and in higher status institutions. This is only partly explained by the slow turnover of faculty positions. While some efforts to address this issue have aimed to support individual women and foster their career success, the National Science Foundation's ADVANCE program has taken a different approach, calling for institutions to take a systemic and organizational approach to enhance women's representation in the academy. Since 2001, some 50 institutions have received ADVANCE Institutional Transformation (IT) awards to develop such systemic approaches. Most ADVANCE-IT projects have attended to structures (e.g. committee and departmental leadership roles), processes (e.g. hiring), policy (e.g. family leave), attitudes and awareness (e.g. training for chairs), and workplace climate, as well as interventions that focus on faculty members as valuable human resources. Our research team is studying ADVANCE institutions' approaches to organizational change, by identifying and categorizing individual change interventions, examining how they combine to build an overall change portfolio, and considering how change interventions are selected or adapted to fit a specific institutional context. Because universities are complex organizations composed of multiple, loosely coupled, interconnected sub-systems, an overall change strategy cannot depend on a single type of intervention. Yet any particular intervention might be deployed on behalf of multiple goals and in a variety of forms that may depend on the context, or institutional system, in which it is introduced. We will discuss some common types of strategic intervention used in ADVANCE-IT projects, categorized by Bolman and Deal's (1991) four main perspectives or "lenses" for understanding organizational issues. The

  9. Formal representation of the requirements for an Advanced Subsonic Civil Transport (ASCT) flight control system

    NASA Technical Reports Server (NTRS)

    Frincke, Deborah; Wolber, Dave; Fisher, Gene; Cohen, Gerald C.; Mclees, R. E.

    1992-01-01

    A partial requirement specification for an Advanced Subsonic Civil Transport (ASCT) Flight Control System is described. The example was adopted from requirements given in a NASA Contractor report. The language used to describe the requirements, Requirements Specification Language (RSL), is described in a companion document.

  10. 78 FR 35746 - Advance Notification to Native American Tribes of Transportation of Certain Shipments of Nuclear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... licensees will be required to provide advance notifications for certain shipments of radioactive material at... for certain shipments of radioactive material at the time the applicable Agreement State implements... B packaging; (2) the licensed material is being transported within or across the boundary of...

  11. National Institute of Biomedical Imaging and Bioengineering Point-of-Care Technology Research Network: Advancing Precision Medicine

    PubMed Central

    Ford Carleton, Penny; Parrish, John A.; Collins, John M.; Crocker, J. Benjamin; Dixon, Ronald F.; Edgman-Levitan, Susan; Lewandrowski, Kent B.; Stahl, James E.; Klapperich, Catherine; Cabodi, Mario; Gaydos, Charlotte A.; Rompalo, Anne M.; Manabe, Yukari; Wang, Tza-Huei; Rothman, Richard; Geddes, Chris D.; Widdice, Lea; Jackman, Joany; Mathura, Rishi A.; Lash, Tiffani Bailey

    2016-01-01

    To advance the development of point-of-care technology (POCT), the National Institute of Biomedical Imaging and Bioengineering established the POCT Research Network (POCTRN), comprised of Centers that emphasize multidisciplinary partnerships and close facilitation to move technologies from an early stage of development into clinical testing and patient use. This paper describes the POCTRN and the three currently funded Centers as examples of academic-based organizations that support collaborations across disciplines, institutions, and geographic regions to successfully drive innovative solutions from concept to patient care. PMID:27730014

  12. NRC review of Electric Power Research Institute`s advanced light water reactor utility requirements document. Passive plant designs, chapters 2-13, project number 669

    SciTech Connect

    Not Available

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the {open_quotes}Advanced Light Water Reactor [ALWR] Utility Requirements Document{close_quotes}, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume I, {open_quotes}ALWR Policy and Summary of Top-Tier Requirements{close_quotes}, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, {open_quotes}NRC Review of Electric Power Research Institute`s Advanced Light Water Reactor Utility Requirements Document - Program Summary{close_quotes}, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff`s review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review.

  13. NRC review of Electric Power Research Institute`s advanced light water reactor utility requirements document. Passive plant designs, chapter 1, project number 669

    SciTech Connect

    Not Available

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the {open_quotes}Advanced Light Water Reactor [ALWR] Utility Requirements Document{close_quotes}, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume 1, {open_quotes}ALWR Policy and Summary of Top-Tier Requirements{close_quotes}, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, {open_quotes}NRC Review of Electric Power Research Institute`s Advanced Light Water Reactor Utility Requirements Document - Program Summary{close_quotes}, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff`s review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review.

  14. Nanofluidic transport through isolated carbon nanotube channels: Advances, controversies, and challenges

    SciTech Connect

    Guo, Shirui; Meshot, Eric R.; Kuykendall, Tevye; Cabrini, Stefano; Fornasiero, Francesco

    2015-06-02

    Owing to their simple chemistry and structure, controllable geometry, and a plethora of unusual yet exciting transport properties, carbon nanotubes (CNTs) have emerged as exceptional channels for fundamental nanofluidic studies, as well as building blocks for future fluidic devices that can outperform current technology in many applications. Leveraging the unique fluidic properties of CNTs in advanced systems requires a full understanding of their physical origin. Recent advancements in nanofabrication technology enable nanofluidic devices to be built with a single, nanometer-wide CNT as a fluidic pathway. These novel platforms with isolated CNT nanochannels offer distinct advantages for establishing quantitative structure–transport correlations in comparison with membranes containing many CNT pores. In addition, they are promising components for single-molecule sensors as well as for building nanotube-based circuits wherein fluidics and electronics can be coupled. With such advanced device architecture, molecular and ionic transport can be manipulated with vastly enhanced control for applications in sensing, separation, detection, and therapeutic delivery. Recent achievements in fabricating isolated-CNT nanofluidic platforms are highlighted, along with the most-significant findings each platform enables for water, ion, and molecular transport. Furthermore, the implications of these findings and remaining open questions on the exceptional fluidic properties of CNTs are also discussed.

  15. Nanofluidic transport through isolated carbon nanotube channels: Advances, controversies, and challenges

    DOE PAGES

    Guo, Shirui; Meshot, Eric R.; Kuykendall, Tevye; ...

    2015-06-02

    Owing to their simple chemistry and structure, controllable geometry, and a plethora of unusual yet exciting transport properties, carbon nanotubes (CNTs) have emerged as exceptional channels for fundamental nanofluidic studies, as well as building blocks for future fluidic devices that can outperform current technology in many applications. Leveraging the unique fluidic properties of CNTs in advanced systems requires a full understanding of their physical origin. Recent advancements in nanofabrication technology enable nanofluidic devices to be built with a single, nanometer-wide CNT as a fluidic pathway. These novel platforms with isolated CNT nanochannels offer distinct advantages for establishing quantitative structure–transport correlationsmore » in comparison with membranes containing many CNT pores. In addition, they are promising components for single-molecule sensors as well as for building nanotube-based circuits wherein fluidics and electronics can be coupled. With such advanced device architecture, molecular and ionic transport can be manipulated with vastly enhanced control for applications in sensing, separation, detection, and therapeutic delivery. Recent achievements in fabricating isolated-CNT nanofluidic platforms are highlighted, along with the most-significant findings each platform enables for water, ion, and molecular transport. Furthermore, the implications of these findings and remaining open questions on the exceptional fluidic properties of CNTs are also discussed.« less

  16. THE JOINT EUROPEAN-UNITED STATES NDEA INSTITUTE FOR ADVANCED STUDY, MANNHEIM-HEIDELBERG.

    ERIC Educational Resources Information Center

    VAN TESLAAR, A.P.

    THE EUROPEAN COORDINATOR AND RESIDENT CO-DIRECTOR OF THE MANNHEIM-HEIDELBERG BRANCH OF THE SUMMER 1966 LANGUAGE INSTITUTE IN FRANCE AND GERMANY PREPARED THIS EVALUATION OF THE INTERNATIONAL VENTURE. DESIGNED TO ANALYZE THE INNOVATIONAL ASPECTS OF THE 1966 INSTITUTE WITH THE IDEA OF STRENGTHENING THE EFFECTIVENESS OF THIS AND SIMILAR PROGRAMS, THE…

  17. Criteria for Laparoscopic Advanced Surgery in Semi-Equipped Setup (CLASS): Feasibility Study Based on Institutional Experience.

    PubMed

    Uday, S K; Bhargav, P R K; Venkata Pavan Kumar, C H

    2014-02-01

    Laparoscopic and Minimally invasive techniques have become a routine practice for various surgical disorders in present times. Though, advanced laparoscopic procedures are feasible they are largely restricted to fewer centers due to lack of advanced instrumentation, finances and expertise at most of them. In this context, we conducted a feasibility study to evolve definite criteria for performing advanced laparoscopic surgeries in resource restricted set-ups. We present our experience with 25 cases of advanced laparoscopic procedures using conventional laparoscopic instruments. We evaluated the clinico-investigative profile and operative details of all the patients. We classified the surgical expertise, laparoscopic instrumentation, surgical set ups and patient factors systematically to evolve the criteria for feasibility of advanced laparoscopicsurgery. Out of the 22 eligible patients for the study, various laparoscopic surgeries performed were - Fundoplication (4), Cystogastrostomy (3), Endoscopic thyroidectomy (7), Thoracoscopic Thyroidectomy (2), Adrenalectomy (5) and Retroperitoneal paraganglioma excision (1). There was no mortality and two morbidities in the form of hypercarbia and a tracheo-cutaneous fistula in 2 cases of endoscopic thyroidectomy. According to the criteria, we propose our surgical set up falls in to Grade 3, for which this criteria fits in. This study demonstrates the feasibility of advanced laparoscopic procedures in semi-equipped set-up, preferably by employing institute specific criteria of CLASS.

  18. Advanced subsonic transport approach noise: The relative contribution of airframe noise

    NASA Technical Reports Server (NTRS)

    Willshire, William L., Jr.; Garber, Donald P.

    1992-01-01

    With current engine technology, airframe noise is a contributing source for large commercial aircraft on approach, but not the major contributor. With the promise of much quieter jet engines with the planned new generation of high-by-pass turbofan engines, airframe noise has become a topic of interest in the advanced subsonic transport research program. The objective of this paper is to assess the contribution of airframe noise relative to the other aircraft noise sources on approach. The assessment will be made for a current technology large commercial transport aircraft and for an envisioned advanced technology aircraft. NASA's Aircraft Noise Prediction Program (ANOPP) will be used to make total aircraft noise predictions for these two aircraft types. Predicted noise levels and areas of noise contours will be used to determine the relative importance of the contributing approach noise sources. The actual set-up decks used to make the ANOPP runs for the two aircraft types are included in appendixes.

  19. Workshop on Critical Issues in Microgravity Fluids, Transport, and Reaction Processes in Advanced Human Support Technology

    NASA Technical Reports Server (NTRS)

    Chiaramonte, Francis P.; Joshi, Jitendra A.

    2004-01-01

    This workshop was designed to bring the experts from the Advanced Human Support Technologies communities together to identify the most pressing and fruitful areas of research where success hinges on collaborative research between the two communities. Thus an effort was made to bring together experts in both advanced human support technologies and microgravity fluids, transport and reaction processes. Expertise was drawn from academia, national laboratories, and the federal government. The intent was to bring about a thorough exchange of ideas and develop recommendations to address the significant open design and operation issues for human support systems that are affected by fluid physics, transport and reaction processes. This report provides a summary of key discussions, findings, and recommendations.

  20. Benefits assessment of Advanced Public Transportation Systems (APTS). Final report, October 1995-July 1996

    SciTech Connect

    Goeddel, D.

    1996-07-30

    This report documents work performed under FTA`s Advanced Public Transportation Systems (APTS) Program, a program structured to undertake research and development of innovative applications of advanced navigation, information, and communication technologies that most benefit public transportation. This report presents the results of an analysis conducted by the Volpe Center, for the FTA, to provide an `order-of-magnitude` estimate of the expected benefits to the transit industry with the application of APTS technologies. Specifically, the study identified and quantified the major benefits derived from current applications of APTS technologies within the transit industry and projected current APTS benefits to a national level based on forecasts and reasonable assumptions on the potential future applications of such technologies within the transit industry.

  1. Advanced public transportation systems deployment in the United States. Final report, July 1995-January 1996

    SciTech Connect

    Casey, R.F.; Labell, L.N.

    1996-08-01

    This report documents work performed under FTA`s Advanced Public Transportation Systems (APTS) Program, a program structured to undertake research and development of innovative applications of advanced navigation, information, and communication technologies that most benefit public transportation. This report is a compilation of existing and planned deployments of APTS technologies and services. The information was collected during the Fall of 1995 and was obtained through contacts with one or more persons at each agency. The objective was to include information from all agencies who submitted information for the 1993 National Transit Database (NTD) Report Year, the last year for which NTD data was available at the time. A total of 464 agencies provided information for this study. Those with no existing or planned APTS systems are not included herein.

  2. The Brain Trust: Advancement Services Helps Institutions Use Data Strategically to Meet Fundraising Goals

    ERIC Educational Resources Information Center

    Medlock, Vicky

    2012-01-01

    It was not all that many years ago that advancement services was thought of as the "back office"--a term that still makes veterans in the field cringe. Historically, the role of advancement services was keeping donor and alumni records up-to-date, processing gifts, sending receipts, and generating fundraising progress reports. However,…

  3. Fuel-cycle greenhouse gas emissions impacts of alternative transportation fuels and advanced vehicle technologies.

    SciTech Connect

    Wang, M. Q.

    1998-12-16

    At an international conference on global warming, held in Kyoto, Japan, in December 1997, the United States committed to reduce its greenhouse gas (GHG) emissions by 7% over its 1990 level by the year 2012. To help achieve that goal, transportation GHG emissions need to be reduced. Using Argonne's fuel-cycle model, I estimated GHG emissions reduction potentials of various near- and long-term transportation technologies. The estimated per-mile GHG emissions results show that alternative transportation fuels and advanced vehicle technologies can help significantly reduce transportation GHG emissions. Of the near-term technologies evaluated in this study, electric vehicles; hybrid electric vehicles; compression-ignition, direct-injection vehicles; and E85 flexible fuel vehicles can reduce fuel-cycle GHG emissions by more than 25%, on the fuel-cycle basis. Electric vehicles powered by electricity generated primarily from nuclear and renewable sources can reduce GHG emissions by 80%. Other alternative fuels, such as compressed natural gas and liquefied petroleum gas, offer limited, but positive, GHG emission reduction benefits. Among the long-term technologies evaluated in this study, conventional spark ignition and compression ignition engines powered by alternative fuels and gasoline- and diesel-powered advanced vehicles can reduce GHG emissions by 10% to 30%. Ethanol dedicated vehicles, electric vehicles, hybrid electric vehicles, and fuel-cell vehicles can reduce GHG emissions by over 40%. Spark ignition engines and fuel-cell vehicles powered by cellulosic ethanol and solar hydrogen (for fuel-cell vehicles only) can reduce GHG emissions by over 80%. In conclusion, both near- and long-term alternative fuels and advanced transportation technologies can play a role in reducing the United States GHG emissions.

  4. An assessment of advanced displays and controls technology applicable to future space transportation systems

    NASA Technical Reports Server (NTRS)

    Hatfield, Jack J.; Villarreal, Diana

    1990-01-01

    The topic of advanced display and control technology is addressed along with the major objectives of this technology, the current state of the art, major accomplishments, research programs and facilities, future trends, technology issues, space transportation systems applications and projected technology readiness for those applications. The holes that may exist between the technology needs of the transportation systems versus the research that is currently under way are addressed, and cultural changes that might facilitate the incorporation of these advanced technologies into future space transportation systems are recommended. Some of the objectives are to reduce life cycle costs, improve reliability and fault tolerance, use of standards for the incorporation of advancing technology, and reduction of weight, volume and power. Pilot workload can be reduced and the pilot's situational awareness can be improved, which would result in improved flight safety and operating efficiency. This could be accomplished through the use of integrated, electronic pictorial displays, consolidated controls, artificial intelligence, and human centered automation tools. The Orbiter Glass Cockpit Display is an example examined.

  5. Noise and economic characteristics of an advanced blended supersonic transport concept

    NASA Technical Reports Server (NTRS)

    Molloy, J. K.; Grantham, W. D.; Neubauer, M. J., Jr.

    1982-01-01

    Noise and economic characteristics were obtained for an advanced supersonic transport concept that utilized wing body blending, a double bypass variable cycle engine, superplastically formed and diffusion bonded titanium in both the primary and secondary structures, and an alternative interior arrangement that provides increased seating capacity. The configuration has a cruise Mach number of 2.62, provisions for 290 passengers, a mission range of 8.19 Mm (4423 n.mi.), and an average operating cruise lift drag ratio of 9.23. Advanced operating procedures, which have the potential to reduce airport community noise, were explored by using a simulator. Traded jet noise levels of 105.7 and 103.4 EPNdB were obtained by using standard and advanced takeoff operational procedures, respectively. A new method for predicting lateral attenuation was utilized in obtaining these jet noise levels.

  6. Evaluation of advanced propulsion options for the next manned transportation system: Propulsion evolution study

    NASA Technical Reports Server (NTRS)

    Spears, L. T.; Kramer, R. D.

    1990-01-01

    The objectives were to examine launch vehicle applications and propulsion requirements for potential future manned space transportation systems and to support planning toward the evolution of Space Shuttle Main Engine (SSME) and Space Transportation Main Engine (STME) engines beyond their current or initial launch vehicle applications. As a basis for examinations of potential future manned launch vehicle applications, we used three classes of manned space transportation concepts currently under study: Space Transportation System Evolution, Personal Launch System (PLS), and Advanced Manned Launch System (AMLS). Tasks included studies of launch vehicle applications and requirements for hydrogen-oxygen rocket engines; the development of suggestions for STME engine evolution beyond the mid-1990's; the development of suggestions for STME evolution beyond the Advanced Launch System (ALS) application; the study of booster propulsion options, including LOX-Hydrocarbon options; the analysis of the prospects and requirements for utilization of a single engine configuration over the full range of vehicle applications, including manned vehicles plus ALS and Shuttle C; and a brief review of on-going and planned LOX-Hydrogen propulsion technology activities.

  7. DART: Delta Advanced Reusable Transport. An alternate manned space system proposal

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Delta Advanced Reusable Transport (DART) craft is being developed to add, multiple, rapid, and cost effective space access to the U.S. capability and to further the efforts towards a permanent space presence. The DART craft provides an augmentative and an alternative system to the Shuttle. As a supplement launch vehicle, the DART adds low cost and easily accessible transport of crew and cargo to specific space destinations to the U.S. program. This adds significant opportunities for manned rated missions that do not require Shuttle capabilities. In its alternative role, the DART can provide emergency space access and satellite repair, the continuation of scientific research, and the furthering of U.S. manned efforts in the event of Shuttle incapabilities. In addition, the DART is being designed for Space Station Freedom compatibility, including its use as a 'lifeboat' emergency reentry craft for Freedom astronauts, as well as the transport of crew and cargo for station resupply.

  8. Recent advances in statistical methods for the estimation of sediment and nutrient transport in rivers

    NASA Astrophysics Data System (ADS)

    Colin, T. A.

    1995-07-01

    This paper reviews advances in methods for estimating fluvial transport of suspended sediment and nutrients. Research from the past four years, mostly dealing with estimating monthly and annual loads, is emphasized. However, because this topic has not appeared in previous IUGG reports, some research prior to 1990 is included. The motivation for studying sediment transport has shifted during the past few decades. In addition to its role in filling reservoirs and channels, sediment is increasingly recognized as an important part of fluvial ecosystems and estuarine wetlands. Many groups want information about sediment transport [Bollman, 1992]: Scientists trying to understand benthic biology and catchment hydrology; citizens and policy-makers concerned about environmental impacts (e.g. impacts of logging [Beschta, 1978] or snow-fences [Sturges, 1992]); government regulators considering the effectiveness of programs to protect in-stream habitat and downstream waterbodies; and resource managers seeking to restore wetlands.

  9. Study on utilization of advanced composites in fuselage structures of large transports

    NASA Technical Reports Server (NTRS)

    Johnson, R. W.; Thomson, L. W.; Wilson, R. D.

    1985-01-01

    The potential for utilizing advanced composites in fuselage structures of large transports was assessed. Six fuselage design concepts were selected and evaluated in terms of structural performance, weight, and manufacturing development and costs. Two concepts were selected that merit further consideration for composite fuselage application. These concepts are: (1) a full depth honeycomb design with no stringers, and (2) an I section stringer stiffened laminate skin design. Weight reductions due to applying composites to the fuselages of commercial and military transports were calculated. The benefits of applying composites to a fleet of military transports were determined. Significant technology issues pertinent to composite fuselage structures were identified and evaluated. Program plans for resolving the technology issues were developed.

  10. Curriculum development for an advanced regional anesthesia education program: one institution's experience from apprenticeship to comprehensive teaching.

    PubMed

    Ouanes, Jean-Pierre P; Schwengel, Deborah; Mathur, Vineesh; Ahmed, Omar I; Hanna, Marie N

    2014-02-01

    Results of recent attitude survey studies suggest that most practicing physicians are inadequately treating postoperative pain. Residents in anesthesia are confident in performing lumbar epidural and spinal anesthesia, but many are not confident in performing the blocks with which they have the least exposure. Changes need to be made in the training processes to a comprehensive model that prepares residents to perform a wider array of blocks in postgraduate practice. Here, we describe one institution's approach to creating a standardized, advanced regional anesthesia curriculum for residents that follows the six core competencies of the ACGME. Residents received training in anatomy dissection, ultrasound-guided regional anesthesia, traditional nerve stimulation techniques, problem-based learning and simulation sessions, oral board presentation sessions, and journal club sessions. Residents kept a detailed log for their use of peripheral nerve block procedures. We have now redesigned and implemented an advanced regional anesthesia program within our institution to provide residents with experience in regional anesthesia at a competent level. Resident's knowledge in regional anesthesia did improve after the first year of implementation as reflected in improvements between the pre- and post-tests. As the advanced regional anesthesia education program continues to improve, we hope to demonstrate levels of validity, reliability, and usability by other programs.

  11. Application of pneumatic lift and control surface technology to advanced transport aircraft

    NASA Technical Reports Server (NTRS)

    Englar, Robert J.

    1996-01-01

    The application of pneumatic (blown) aerodynamic technology to both the lifting and the control surfaces of advanced transport aircraft can provide revolutionary changes in the performance and operation of these vehicles, ranging in speed regime from Advanced Subsonic Transports to the High Speed Civil Transport, and beyond. This technology, much of it based on the Circulation Control Wing blown concepts, can provide aerodynamic force augmentations of 80 to 100 (i.e., return of 80-100 pounds of force per pound of input momentum from the blowing jet). This can be achieved without use of external mechanical surfaces. Clever application of this technology can provide no-moving-part lifting surfaces (wings/tails) integrated into the control system to greatly simplify aircraft designs while improving their aerodynamic performance. Lift/drag ratio may be pneumatically tailored to fit the current phase of the flight, and takeoff/landing performance can be greatly improved by reducing ground roll distances and liftoff/touchdown speeds. Alternatively, great increases in liftoff weights and payloads are possible, as are great reductions in wing and tail planform size, resulting in optimized cruise wing designs. Furthermore, lift generation independent of angle of attack provides much promise for increased safety of flight in the severe updrafts/downdrafts of microbursts and windshears, which is further augmented by the ability to sustain flight at greatly reduced airspeeds. Load-tailored blown wings can also reduce tip vorticity during highlift operations and the resulting vortex wake hazards near terminal areas. Reduced noise may also be possible as these jets can be made to operate at low pressures. The planned presentation will support the above statements through discussions of recent experimental and numerical (CFD) research and development of these advanced blown aerodynamic surfaces, portions of which have been conducted for NASA. Also to be presented will be

  12. 78 FR 18933 - Proposed Priority-National Institute on Disability and Rehabilitation Research-Advanced...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION 34...--Advanced Rehabilitation Research Training Program AGENCY: Office of Special Education and Rehabilitative Services, Department of Education. ACTION: Proposed priority. SUMMARY: The Assistant Secretary for...

  13. Academic and Career Advancement for Black Male Athletes at NCAA Division I Institutions

    ERIC Educational Resources Information Center

    Baker, Ashley R.; Hawkins, Billy J.

    2016-01-01

    This chapter examines the structural arrangements and challenges many Black male athletes encounter as a result of their use of sport for upward social mobility. Recommendations to enhance their preparation and advancement are provided.

  14. Screening stress factors survey in an institute of advanced studies: health and safety integrated plans.

    PubMed

    Fonseca, C S; Gomes, C N; Barros, F S

    2012-01-01

    The current paper presents the study of organizational stressors survey carried out in a military institute, responsible for researches of high demand on aerospace technology. The study considered the theoretical framework of Organizational Ergonomics, combined with the technical guidelines of Psychology applied to Work Safety. The participatory approach was used on daily work assessment and decision making, aiming the adoption of corrective and preventive measures, considering possible distortions and imbalances between prescribed and actual activities. Thus, it was sought to engage and encourage the participation of the Institute's workers in the reflection/creation of better solutions to daily problems and to achieve productivity, without prejudice in the occupational health and safety.

  15. "The Hopi Followers": Chief Tawaquaptewa and Hopi Student Advancement at Sherman Institute, 1906-1909

    ERIC Educational Resources Information Center

    Gilbert, Matthew T. Sakiestewa

    2005-01-01

    Arizona, 71 Hopi pupils left their families and homes to attend Sherman Institute, an off-reservation Indian boarding school in Riverside, California. Accompanied by their Kikmongwi (Village Chief), Tawaquaptewa and other Hopi leaders, the Hopis embarked on an adventure that forever changed their lives. For the majority of Hopi students, the…

  16. Mentoring 101: Advancing African-American Women Faculty and Doctoral Student Success in Predominantly White Institutions

    ERIC Educational Resources Information Center

    Grant, Cosette M.; Ghee, Sarah

    2015-01-01

    This article is purposed with operationalizing the concept of mentoring as a nuanced approach and attempt to thwart the upward trajectories of African-American women in predominantly White institutions (PWIs). We struggled as African-American women to balance and decipher the various facets inherent in our respective roles--professor and doctoral…

  17. Onboarding Experiences: An Examination of Early Institutional Advancement Professionals' Decisions

    ERIC Educational Resources Information Center

    Radosh, Meghan E.

    2013-01-01

    Onboarding is a new employee orientation process that is designed to formalize and socialize new hires to an organization, or in this case higher education institutions. The onboarding experience that many new employees have can shape employee views and first impressions of their new employer, and shape their early career path to stay or leave…

  18. Minority-Serving Institutions and Their Contribution to Advancing Multicultural Teacher Education Pedagogy

    ERIC Educational Resources Information Center

    Brooks, Michael; West-Olatunji, Cirecie; Blackmon, Angelicque Tucker; Froelich, Kathy; De La Torre, William; Montano, Theresa; Peregrino, Sylvia; Quintanar, Rosalinda; Smith, Rosamond J.

    2012-01-01

    As enrollment of ethnically diverse students continues to increase, so should the number of teachers increase who are trained in multicultural education methods. Traditionally, those culturally competent educators come from Minority Serving Institutions. Given the lack of current research or data on the benefits of this type of teaching at MSIs…

  19. Institutional Influences on Nurse-Academics' Instructional Planning Decisions in the Implementation of Basic Nursing Curricula in Colleges of Advanced Education in New South Wales.

    ERIC Educational Resources Information Center

    Roberts, Kathryn L.

    A study examined institutional influences on the instructional planning decisions of nurse-academics presenting basic nursing curricula in colleges of advanced education (CAEs) in New South Wales. Data were collected from the following sources: survey of 86 selected nurse-academics from 12 of New South Wales' 15 tertiary institutions running basic…

  20. Development of Advanced Methods of Structural and Trajectory Analysis for Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Ardema, Mark D.

    1996-01-01

    In this report the author describes: (1) development of advanced methods of structural weight estimation, and (2) development of advanced methods of flight path optimization. A method of estimating the load-bearing fuselage weight and wing weight of transport aircraft based on fundamental structural principles has been developed. This method of weight estimation represents a compromise between the rapid assessment of component weight using empirical methods based on actual weights of existing aircraft and detailed, but time-consuming, analysis using the finite element method. The method was applied to eight existing subsonic transports for validation and correlation. Integration of the resulting computer program, PDCYL, has been made into the weights-calculating module of the AirCraft SYNThesis (ACSYNT) computer program. ACSYNT bas traditionally used only empirical weight estimation methods; PDCYL adds to ACSYNT a rapid, accurate means of assessing the fuselage and wing weights of unconventional aircraft. PDCYL also allows flexibility in the choice of structural concept, as well as a direct means of determining the impact of advanced materials on structural weight.

  1. Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm

    NASA Technical Reports Server (NTRS)

    Robinson, John W.; McCleskey, Carey M.; Rhodes, Russel E.; Lepsch, Roger A.; Henderson, Edward M.; Joyner, Claude R., III; Levack, Daniel J. H.

    2013-01-01

    This paper describes Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm. It builds on the work of the previous paper "Approach to an Affordable and Productive Space Transportation System". The scope includes both flight and ground system elements, and focuses on their compatibility and capability to achieve a technical solution that is operationally productive and also affordable. A clear and revolutionary approach, including advanced propulsion systems (advanced LOX rich booster engine concept having independent LOX and fuel cooling systems, thrust augmentation with LOX rich boost and fuel rich operation at altitude), improved vehicle concepts (autogeneous pressurization, turbo alternator for electric power during ascent, hot gases to purge system and keep moisture out), and ground delivery systems, was examined. Previous papers by the authors and other members of the Space Propulsion Synergy Team (SPST) focused on space flight system engineering methods, along with operationally efficient propulsion system concepts and technologies. This paper continues the previous work by exploring the propulsion technology aspects in more depth and how they may enable the vehicle designs from the previous paper. Subsequent papers will explore the vehicle design, the ground support system, and the operations aspects of the new delivery paradigm in greater detail.

  2. Advanced transportation system studies. Technical area 2: Heavy lift launch vehicle development. Volume 2; Technical Results

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Sections 10 to 13 of the Advanced Transportation System Studies final report are included in this volume. Section 10 contains a copy of an executive summary that was prepared by Lockheed Space Operations Company (LSOC) to document their support to the TA-2 contract during the first-year period of performance of the contract, May 1992 through May 1993. LSOC participated on the TA-2 contract as part of the concurrent engineering launch system definition team, and provided outstanding heavy lift launch vehicle (HLLV) ground operations requirements and concept assessments for Lockheed Missiles and Space Company (LMSC) through an intercompany work transfer as well as providing specific HLLV ground operations assessments at the direction of NASA KSC through KSC funding that was routed to the TA-2 contract. Section 11 contains a copy of a vehicle-independent, launch system health management requirements assessment. The purpose of the assessment was to define both health management requirements and the associated interfaces between a generic advanced transportation system launch vehicle and all related elements of the entire transportation system, including the ground segment. Section 12 presents the major TA-2 presentations provided to summarize the significant results and conclusions that were developed over the course of the contract. Finally, Section 13 presents the design and assessment report on the first lunar outpost heavy lift launch vehicle.

  3. The NASA Solar System Exploration Virtual Institute: International Efforts in Advancing Lunar Science with Prospects for the Future

    NASA Technical Reports Server (NTRS)

    Schmidt, Gregory K.

    2014-01-01

    The NASA Solar System Exploration Research Virtual Institute (SSERVI), originally chartered in 2008 as the NASA Lunar Science Institute (NLSI), is chartered to advance both the scientific goals needed to enable human space exploration, as well as the science enabled by such exploration. NLSI and SSERVI have in succession been "institutes without walls," fostering collaboration between domestic teams (7 teams for NLSI, 9 for SSERVI) as well as between these teams and the institutes' international partners, resulting in a greater global endeavor. SSERVI teams and international partners participate in sharing ideas, information, and data arising from their respective research efforts, and contribute to the training of young scientists and bringing the scientific results and excitement of exploration to the public. The domestic teams also respond to NASA's strategic needs, providing community-based responses to NASA needs in partnership with NASA's Analysis Groups. Through the many partnerships enabled by NLSI and SSERVI, scientific results have well exceeded initial projections based on the original PI proposals, proving the validity of the virtual institute model. NLSI and SSERVI have endeavored to represent not just the selected and funded domestic teams, but rather the entire relevant scientific community; this has been done through many means such as the annual Lunar Science Forum (now re-named Exploration Science Forum), community-based grass roots Focus Groups on a wide range of topics, and groups chartered to further the careers of young scientists. Additionally, NLSI and SSERVI have co-founded international efforts such as the pan-European lunar science consortium, with an overall goal of raising the tide of lunar science (and now more broadly exploration science) across the world.

  4. Surviving the New Normal: Strategies for Institutional Advancement that Cut across Organizations

    ERIC Educational Resources Information Center

    Budd, Steven

    2011-01-01

    The current discourse on community college leadership makes much ado about the "new normal," or the collective influence of the social, economic, and political conditions under which people advance their organizations. To succeed in a changed environment, community colleges--many confronted with drastic budget cuts--must find ways to raise money…

  5. Advanced Cancer Genomics Institute: Genetic Signatures and Therapeutic Targets in Cancer Progression

    DTIC Science & Technology

    2015-04-01

    Covaris E210: DNA shearer used to produce next-gen libraries v) Caliper Sciclone: liquid handling robotic station vi) Autoloader-2: robotic platform...the NGS capabilities funded through the NFGC/TATRC mechanism have been published: 1. Hennon MW, Yendamuri S. Advances in lung cancer surgery . J

  6. 75 FR 7990 - Use of Community Development Loans by Community Financial Institutions To Secure Advances...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... housing likely would qualify as eligible security for advances as mortgages or other real estate-related... affect the status of home equity loans as other real estate-related collateral eligible to secure... than real estate. In addition, any eligible community development loan would have to have a...

  7. Propulsion/ASME Rocket-Based Combined Cycle Activities in the Advanced Space Transportation Program Office

    NASA Technical Reports Server (NTRS)

    Hueter, Uwe; Turner, James

    1998-01-01

    NASA's Office Of Aeronautics and Space Transportation Technology (OASTT) has establish three major coals. "The Three Pillars for Success". The Advanced Space Transportation Program Office (ASTP) at the NASA's Marshall Space Flight Center in Huntsville,Ala. focuses on future space transportation technologies under the "Access to Space" pillar. The Advanced Reusable Technologies (ART) Project, part of ASTP, focuses on the reusable technologies beyond those being pursued by X-33. The main activity over the past two and a half years has been on advancing the rocket-based combined cycle (RBCC) technologies. In June of last year, activities for reusable launch vehicle (RLV) airframe and propulsion technologies were initiated. These activities focus primarily on those technologies that support the year 2000 decision to determine the path this country will take for Space Shuttle and RLV. In February of this year, additional technology efforts in the reusable technologies were awarded. The RBCC effort that was completed early this year was the initial step leading to flight demonstrations of the technology for space launch vehicle propulsion. Aerojet, Boeing-Rocketdyne and Pratt & Whitney were selected for a two-year period to design, build and ground test their RBCC engine concepts. In addition, ASTROX, Pennsylvania State University (PSU) and University of Alabama in Huntsville also conducted supporting activities. The activity included ground testing of components (e.g., injectors, thrusters, ejectors and inlets) and integrated flowpaths. An area that has caused a large amount of difficulty in the testing efforts is the means of initiating the rocket combustion process. All three of the prime contractors above were using silane (SiH4) for ignition of the thrusters. This follows from the successful use of silane in the NASP program for scramjet ignition. However, difficulties were immediately encountered when silane (an 80/20 mixture of hydrogen/silane) was used for rocket

  8. The development and evaluation of advanced technology laminar-flow-control subsonic transport aircraft

    NASA Technical Reports Server (NTRS)

    Sturgeon, R. F.

    1978-01-01

    A study was conducted to evaluate the technical and economic feasibility of applying laminar flow control (LFC) to the wings and empennage of long-range subsonic transport aircraft for initial operation in 1985. For a design mission range of 5500 n mi, advanced technology LFC and turbulent-flow aircraft were developed for a 200-passenger payload, and compared on the basis of production costs, direct operating costs, and fuel efficiency. Parametric analyses were conducted to establish optimum geometry, advanced system concepts were evaluated, and configuration variations maximizing the effectiveness of LFC were developed. The final comparisons include consideation of maintenance costs and procedures, manufacturing costs and procedures, and operational considerations peculiar to LFC aircraft.

  9. A Distributed Simulation Facility to Support Human Factors Research in Advanced Air Transportation Technology

    NASA Technical Reports Server (NTRS)

    Amonlirdviman, Keith; Farley, Todd C.; Hansman, R. John, Jr.; Ladik, John F.; Sherer, Dana Z.

    1998-01-01

    A distributed real-time simulation of the civil air traffic environment developed to support human factors research in advanced air transportation technology is presented. The distributed environment is based on a custom simulation architecture designed for simplicity and flexibility in human experiments. Standard Internet protocols are used to create the distributed environment, linking all advanced cockpit simulator, all Air Traffic Control simulator, and a pseudo-aircraft control and simulation management station. The pseudo-aircraft control station also functions as a scenario design tool for coordinating human factors experiments. This station incorporates a pseudo-pilot interface designed to reduce workload for human operators piloting multiple aircraft simultaneously in real time. The application of this distributed simulation facility to support a study of the effect of shared information (via air-ground datalink) on pilot/controller shared situation awareness and re-route negotiation is also presented.

  10. Inward particle transport at high collisionality in the Experimental Advanced Superconducting Tokamak

    SciTech Connect

    Wang, G. Q.; Ma, J.; Weiland, J.; Zang, Q.

    2013-10-15

    We have made the first drift wave study of particle transport in the Experimental Advanced Superconducting Tokamak (Wan et al., Nucl. Fusion 49, 104011 (2009)). The results reveal that collisions make the particle flux more inward in the high collisionality regime. This can be traced back to effects that are quadratic in the collision frequency. The particle pinch is due to electron trapping which is not very efficient in the high collisionality regime so the approach to equilibrium is slow. We have included also the electron temperature gradient (ETG) mode to give the right electron temperature gradient, since the Trapped Electron Mode (TE mode) is weak in this regime. However, at the ETG mode number ions are Boltzmann distributed so the ETG mode does not give particle transport.

  11. Advanced Transport Operating System (ATOPS) Flight Management/Flight Controls (FM/FC) software description

    NASA Technical Reports Server (NTRS)

    Wolverton, David A.; Dickson, Richard W.; Clinedinst, Winston C.; Slominski, Christopher J.

    1993-01-01

    The flight software developed for the Flight Management/Flight Controls (FM/FC) MicroVAX computer used on the Transport Systems Research Vehicle for Advanced Transport Operating Systems (ATOPS) research is described. The FM/FC software computes navigation position estimates, guidance commands, and those commands issued to the control surfaces to direct the aircraft in flight. Various modes of flight are provided for, ranging from computer assisted manual modes to fully automatic modes including automatic landing. A high-level system overview as well as a description of each software module comprising the system is provided. Digital systems diagrams are included for each major flight control component and selected flight management functions.

  12. Advanced Transport Operating System (ATOPS) color displays software description microprocessor system

    NASA Technical Reports Server (NTRS)

    Slominski, Christopher J.; Plyler, Valerie E.; Dickson, Richard W.

    1992-01-01

    This document describes the software created for the Sperry Microprocessor Color Display System used for the Advanced Transport Operating Systems (ATOPS) project on the Transport Systems Research Vehicle (TSRV). The software delivery known as the 'baseline display system', is the one described in this document. Throughout this publication, module descriptions are presented in a standardized format which contains module purpose, calling sequence, detailed description, and global references. The global reference section includes procedures and common variables referenced by a particular module. The system described supports the Research Flight Deck (RFD) of the TSRV. The RFD contains eight cathode ray tubes (CRTs) which depict a Primary Flight Display, Navigation Display, System Warning Display, Takeoff Performance Monitoring System Display, and Engine Display.

  13. Advanced Transport Operating System (ATOPS) color displays software description: MicroVAX system

    NASA Technical Reports Server (NTRS)

    Slominski, Christopher J.; Plyler, Valerie E.; Dickson, Richard W.

    1992-01-01

    This document describes the software created for the Display MicroVAX computer used for the Advanced Transport Operating Systems (ATOPS) project on the Transport Systems Research Vehicle (TSRV). The software delivery of February 27, 1991, known as the 'baseline display system', is the one described in this document. Throughout this publication, module descriptions are presented in a standardized format which contains module purpose, calling sequence, detailed description, and global references. The global references section includes subroutines, functions, and common variables referenced by a particular module. The system described supports the Research Flight Deck (RFD) of the TSRV. The RFD contains eight Cathode Ray Tubes (CRTs) which depict a Primary Flight Display, Navigation Display, System Warning Display, Takeoff Performance Monitoring System Display, and Engine Display.

  14. Technology requirements for advanced earth-orbital transportation systems, dual-mode propulsion

    NASA Technical Reports Server (NTRS)

    Haefeli, R. C.; Littler, E. G.; Hurley, J. B.; Winter, M. G.

    1977-01-01

    The application of dual-mode propulsion concepts to fully reusable single-stage-to-orbit (SSTO) vehicles is discussed. Dual-mode propulsion uses main rocket engines that consume hydrocarbon fuels as well as liquid hydrogen fuel. Liquid oxygen is used as the oxidizer. These engine concepts were integrated into transportation vehicle designs capable of vertical takeoff, delivering a payload to earth orbit, and return to earth with a horizontal landing. Benefits of these vehicles were assessed and compared with vehicles using single-mode propulsion (liquid hydrogen and oxygen engines). Technology requirements for such advanced transportation systems were identified. Figures of merit, including life-cycle cost savings and research costs, were derived for dual-mode technology programs, and were used for assessments of potential benefits of proposed technology activities. Dual-mode propulsion concepts display potential for significant cost and performance benefits when applied to SSTO vehicles.

  15. Propulsion system studies for an advanced high subsonic, long range jet commercial transport aircraft

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Propulsion system characteristics for a long range, high subsonic (Mach 0.90 - 0.98), jet commercial transport aircraft are studied to identify the most desirable cycle and engine configuration and to assess the payoff of advanced engine technologies applicable to the time frame of the late 1970s to the mid 1980s. An engine parametric study phase examines major cycle trends on the basis of aircraft economics. This is followed by the preliminary design of two advanced mixed exhaust turbofan engines pointed at two different technology levels (1970 and 1985 commercial certification for engines No. 1 and No. 2, respectively). The economic penalties of environmental constraints - noise and exhaust emissions - are assessed. The highest specific thrust engine (lowest bypass ratio for a given core technology) achievable with a single-stage fan yields the best economics for a Mach 0.95 - 0.98 aircraft and can meet the noise objectives specified, but with significant economic penalties. Advanced technologies which would allow high temperature and cycle pressure ratios to be used effectively are shown to provide significant improvement in mission performance which can partially offset the economic penalties incurred to meet lower noise goals. Advanced technology needs are identified; and, in particular, the initiation of an integrated fan and inlet aero/acoustic program is recommended.

  16. Application of Advanced Technologies to Small, Short-haul Air Transports

    NASA Technical Reports Server (NTRS)

    Adcock, C.; Coverston, C.; Knapton, B.

    1980-01-01

    A study was conducted of the application of advanced technologies to small, short-haul transport aircraft. A three abreast, 30 passenger design for flights of approximately 100 nautical miles was evaluated. Higher wing loading, active flight control, and a gust alleviation system results in improved ride quality. Substantial savings in fuel and direct operating cost are forecast. An aircraft of this configuration also has significant benefits in forms of reliability and operability which should enable it to sell a total of 450 units through 1990, of which 80% are for airline use.

  17. Characterization of an Integral Thermal Protection and Cryogenic Insulation Material for Advanced Space Transportation Vehicles

    NASA Technical Reports Server (NTRS)

    Salerno, L. J.; White, S. M.; Helvensteijn, B. P. M.

    2000-01-01

    NASA's planned advanced space transportation vehicles will benefit from the use of integral/conformal cryogenic propellant tanks which will reduce the launch weight and lower the earth-to-orbit costs considerably. To implement the novel concept of integral/conformal tanks requires developing an equally novel concept in thermal protection materials. Providing insulation against reentry heating and preserving propellant mass can no longer be considered separate problems to be handled by separate materials. A new family of materials, Superthermal Insulation (STI), has been conceiving and investigated by NASA's Ames Research Center to simultaneously provide both thermal protection and cryogenic insulation in a single, integral material.

  18. Key Metrics and Goals for NASA's Advanced Air Transportation Technologies Program

    NASA Technical Reports Server (NTRS)

    Kaplan, Bruce; Lee, David

    1998-01-01

    NASA's Advanced Air Transportation Technologies (AATT) program is developing a set of decision support tools to aid air traffic service providers, pilots, and airline operations centers in improving operations of the National Airspace System (NAS). NASA needs a set of unifying metrics to tie these efforts together, which it can use to track the progress of the AATT program and communicate program objectives and status within NASA and to stakeholders in the NAS. This report documents the results of our efforts and the four unifying metrics we recommend for the AATT program. They are: airport peak capacity, on-route sector capacity, block time and fuel, and free flight-enabling.

  19. An example of requirements for Advanced Subsonic Civil Transport (ASCT) flight control system using structured techniques

    NASA Technical Reports Server (NTRS)

    Mclees, Robert E.; Cohen, Gerald C.

    1991-01-01

    The requirements are presented for an Advanced Subsonic Civil Transport (ASCT) flight control system generated using structured techniques. The requirements definition starts from initially performing a mission analysis to identify the high level control system requirements and functions necessary to satisfy the mission flight. The result of the study is an example set of control system requirements partially represented using a derivative of Yourdon's structured techniques. Also provided is a research focus for studying structured design methodologies and in particular design-for-validation philosophies.

  20. Ultraclean Fuels Production and Utilization for the Twenty-First Century: Advances toward Sustainable Transportation Fuels

    SciTech Connect

    Fox, Elise B.; Liu, Zhong-Wen; Liu, Zhao-Tie

    2013-11-21

    Ultraclean fuels production has become increasingly important as a method to help decrease emissions and allow the introduction of alternative feed stocks for transportation fuels. Established methods, such as Fischer-Tropsch, have seen a resurgence of interest as natural gas prices drop and existing petroleum resources require more intensive clean-up and purification to meet stringent environmental standards. This review covers some of the advances in deep desulfurization, synthesis gas conversion into fuels and feed stocks that were presented at the 245th American Chemical Society Spring Annual Meeting in New Orleans, LA in the Division of Energy and Fuels symposium on "Ultraclean Fuels Production and Utilization".

  1. Institute for Mechanical Engineering

    NASA Astrophysics Data System (ADS)

    The Institute of Mechanical Engineering has the objectives of supporting in Canada the following activities: improvement of vehicles, propulsion systems, and transportation-related facilities and services; improvements in the design and operation of maritime engineering works; protection of the environment; enhancement of energy flexibility; advancement of firms engaged in manufacturing and resource extraction; and related programs of other government departments and agencies. In 1990-91 the Institute, which had changed its name that year from the Division of Mechanical Engineering, consolidated its research activities from nine laboratories to six programs. Activities in these six programs are described: Advanced Manufacturing Technology, Coastal Zone Engineering, Cold Regions Engineering, Combustion and Fluids Engineering, Ground Transportation Technology, and Machinery and Engine Technology.

  2. NATO (North Atlantic Treaty Organization) Advanced Study Institute Fast Reactions in Energetic Systems

    DTIC Science & Technology

    1980-07-01

    Chief. ,i #’ - r: [" k I TABLE OF CONTEhTS Page No. ORGANIZING COHITTEE 1 A. -FAST REACTIONS AND ENERGY TRANSFER PROCESSESI ADVANCED DIAGNOSTICS. , 3...Subpicosecond Spearroscopies. Lecture II. Phocophysics of Electr - nically 9 Excited States Lecture 111. Chemical Reactivity of Electronically 9 Excited...Excitation by High 12 Energy Electrons Lecture 11. Pulse Radiolysis; Formation of 13 Organic Anions and Cations Lecture III. Fast Reactions of Organic

  3. Core Program in the Joint Institute for Advancement of Flight Sciences

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Following the precedent started several years ago, each of the graduating MS and DSc candidates in JIAFS present a seminar which is advertised throughout the area. Following the formal seminar the attendees are excused and the review committee examines the student as in a standard thesis defense. This allows the students to gain experience in presenting their research and disseminating the Institute's research results to a wider audience. A list of seminars are given in Appendix B. Some 172 excellent applications for the Graduate Research Scholar Assistantships were received during this period. Forty-nine new GRSA were appointed by Professor Whitesides to JTAFS under the various research grants and contracts.

  4. Research advances at the Institute for Nutritional Sciences at Shanghai, China.

    PubMed

    Chen, Yan; Lin, Xu; Liu, Yong; Xie, Dong; Fang, Jing; Le, Yingying; Ke, Zunji; Zhai, Qiwei; Wang, Hui; Guo, Feifan; Wang, Fudi; Liu, Yi

    2011-09-01

    Nutrition-related health issues have emerged as a major threat to public health since the rebirth of the economy in China starting in the 1980s. To meet this challenge, the Chinese Academy of Sciences established the Institute for Nutritional Sciences (INS) at Shanghai, China ≈ 8 y ago. The mission of the INS is to apply modern technologies and concepts in nutritional research to understand the molecular mechanism and provide means of intervention in the combat against nutrition-related diseases, including type 2 diabetes, metabolic syndrome, obesity, cardiovascular diseases, and many types of cancers. Through diligent and orchestrated efforts by INS scientists, graduate students, and research staff in the past few years, the INS has become the leading institution in China in the areas of basic nutritional research and metabolic regulation. Scientists at the INS have made important progress in many areas, including the characterization of genetic and nutritional properties of the Chinese population, metabolic control associated with nutrient sensing, molecular mechanisms underlying glucose and lipid metabolism, regulation of metabolism by adipokines and inflammatory pathways, disease intervention using functional foods or extracts of Chinese herbs, and many biological studies related to carcinogenesis. The INS will continue its efforts in understanding the optimal nutritional needs for Chinese people and the molecular causes associated with metabolic diseases, thus paving the way for effective and individualized intervention in the future. This review highlights the major research endeavors undertaken by INS scientists in recent years.

  5. The NASA Solar System Exploration Virtual Institute: International Efforts in Advancing Lunar Science with Prospects for the Future

    NASA Astrophysics Data System (ADS)

    Schmidt, Gregory

    The NASA Solar System Exploration Research Virtual Institute (SSERVI), originally chartered in 2008 as the NASA Lunar Science Institute (NLSI), is chartered to advance both the scientific goals needed to enable human space exploration, as well as the science enabled by such exploration. NLSI and SSERVI have in succession been “institutes without walls,” fostering collaboration between domestic teams (7 teams for NLSI, 9 for SSERVI) as well as between these teams and the institutes’ international partners, resulting in a greater global endeavor. SSERVI teams and international partners participate in sharing ideas, information, and data arising from their respective research efforts, and contribute to the training of young scientists and bringing the scientific results and excitement of exploration to the public. The domestic teams also respond to NASA’s strategic needs, providing community-based responses to NASA needs in partnership with NASA’s Analysis Groups. Through the many partnerships enabled by NLSI and SSERVI, scientific results have well exceeded initial projections based on the original PI proposals, proving the validity of the virtual institute model. NLSI and SSERVI have endeavored to represent not just the selected and funded domestic teams, but rather the entire relevant scientific community; this has been done through many means such as the annual Lunar Science Forum (now re-named Exploration Science Forum), community-based grass roots Focus Groups on a wide range of topics, and groups chartered to further the careers of young scientists. Additionally, NLSI and SSERVI have co-founded international efforts such as the pan-European lunar science consortium, with an overall goal of raising the tide of lunar science (and now more broadly exploration science) across the world.

  6. The Critical Path Institute's approach to precompetitive sharing and advancing regulatory science.

    PubMed

    Woosley, R L; Myers, R T; Goodsaid, F

    2010-05-01

    Many successful large industries, such as computer-chip manufacturers, the cable television industry, and high-definition television developers,(1) have established successful precompetitive collaborations focusing on standards, applied science, and technology that advance the field for all stakeholders and benefit the public.(2) The pharmaceutical industry, however, has a well-earned reputation for fierce competition and did not demonstrate willingness to share data or knowledge until the US Food and Drug Administration (FDA) launched the Critical Path Initiative in 2004 (ref. 3).

  7. The Unmanned Research Airplane Facility at the Cyprus Institute: Advanced Atmospheric Observations

    NASA Astrophysics Data System (ADS)

    Lange, Manfred A.; Argyrides, Marios; Ioannou, Stelios; Keleshis, Christos

    2014-05-01

    Unmanned Aerial Systems (UASs) have been established as versatile tools for different applications, providing data and observations for atmospheric and Earth-Systems research. They provide an urgently needed link between in-situ ground based measurements and satellite remote sensing observations and are distinguished by significant versatility, flexibility and moderate operational costs. Building on an earlier project (Autonomous Flying Platforms for Atmospheric and Earth Surface Observations project; APAESO) of the Energy, Environment and Water Research Center (EEWRC) at the Cyprus Institute (APAESO is co-financed by the European Development Fund and the Republic of Cyprus through the Cyprus Research Promotion Foundation), we have built up an Unmanned Research Aircraft Facility at The Cyprus Institute (CyI-URAF). The basic components of this facility comprise four CRUISERS airplanes (ET-Air, Slovakia) as UAS platforms, a substantial range of scientific instruments to be flown on these platforms, a mobile Ground Control Station and a well-equipped workshop and calibration laboratory. The APAESO platforms are suitable to carrying out atmospheric and earth-surface observations in the (Eastern) Mediterranean (and elsewhere). They enable 3D measurements for determining physical, chemical and radiative atmospheric properties, aerosol and dust concentrations and atmospheric dynamics as well as 2D investigations into land management practices, vegetation and agricultural mapping, contaminant detection and the monitoring and assessment of hydrological parameters and processes of a given region at high spatial resolution. We will report on some of the essential modifications of the platforms and some of the instrumentation that were instrumental in preparing the research airplanes for a variety of collaborative research projects with. The first scientific mission involved the employment of a DOAS-system (Differential Optical Absorption Spectroscopy) in cooperation with

  8. Study of utilization of advanced composites in fuselage structures of large transports

    NASA Technical Reports Server (NTRS)

    Jackson, A. C.; Campion, M. C.; Pei, G.

    1984-01-01

    The effort required by the transport aircraft manufacturers to support the introduction of advanced composite materials into the fuselage structure of future commercial and military transport aircraft is investigated. Technology issues, potential benefits to military life cycle costs and commercial operating costs, and development plans are examined. The most urgent technology issues defined are impact dynamics, acoustic transmission, pressure containment and damage tolerance, post-buckling, cutouts, and joints and splices. A technology demonstration program is defined and a rough cost and schedule identified. The fabrication and test of a full-scale fuselage barrel section is presented. Commercial and military benefits are identified. Fuselage structure weight savings from use of advanced composites are 16.4 percent for the commercial and 21.8 percent for the military. For the all-composite airplanes the savings are 26 percent and 29 percent, respectively. Commercial/operating costs are reduced by 5 percent for the all-composite airplane and military life cycle costs by 10 percent.

  9. Study of the application of advanced technologies to long-range transport aircraft. Volume 2: Research and development requirements

    NASA Technical Reports Server (NTRS)

    Lange, R. H.; Sturgeon, R. F.; Adams, W. E.; Bradley, E. S.; Cahill, J. F.; Eudaily, R. R.; Hancock, J. P.; Moore, J. W.

    1972-01-01

    Investigations were conducted to evaluate the relative benefits attainable through the exploitation of advanced technologies and to identify future research and development efforts required to permit the application of selected technologies to transport aircraft entering commercial operation in 1985. Results show that technology advances, particularly in the areas of composite materials, supercritical aerodynamics, and active control systems, will permit the development of long-range, high-payload commercial transports operating at high-subsonic speeds with direct operating costs lower than those of current aircraft. These advanced transports also achieve lower noise levels and lower engine pollutant emissions than current transports. Research and development efforts, including analytical investigations, laboratory test programs, and flight test programs, are required in essentially all technology areas to achieve the potential technology benefits.

  10. New advances in the pathophysiology of intestinal ion transport and barrier function in diarrhea and the impact on therapy.

    PubMed

    Hoque, Kazi Mirajul; Chakraborty, Subhra; Sheikh, Irshad Ali; Woodward, Owen M

    2012-06-01

    Diarrhea remains a continuous threat to human health worldwide. Scaling up the best practices for diarrhea prevention requires improved therapies. Diarrhea results from dysregulation of normal intestinal ion transport functions. Host-microbe contact is a key determinant of this response. Underlying mechanisms in the disease state are regulated by intracellular signals that modulate the activity of individual transport proteins responsible for ion transport and barrier function. Similarly, virulence factors of pathogens and their complex interaction with the host has shed light on the mechanism of enteric infection. Great advances in our understanding of the pathophysiologic mechanisms of epithelial transport, and host-microbe interaction have been made in recent years. Application of these new advances may represent strategies to decrease pathogen attachment, enhance intestinal cation absorption, decrease anion secretion and repair barrier function. This review highlights the new advances and better understanding in the pathophysiology of diarrheal diseases and their impact on therapy.

  11. Advanced public transportation systems: The state of the art, update `96. Final report, July 1995-December 1996

    SciTech Connect

    Casey, R.F.; Labell, L.N.; Holmstrom, R.; LoVecchio, J.A.; Schweiger, C.L.

    1996-01-01

    This report documents work performed under FTA`s Advanced Public Transportation Systems (APTS) Program, a program structured to undertake research and development of innovative applications of advanced navigation, information, and communication technologies that most benefit public transportation. This report is the latest in a series of State-of-the-Art reports, the last of which was published in January 1994. It contains the results of an investigation of the extent of adoption of advanced technology in the provision of public transportation service in North America. It focused on some of the most innovative or comprehensive implementations, categorized under four types of services/technologies: Fleet Management, Traveler Information, Electronic Fare Payment, and Transportation Demand Management.

  12. Advances in the archiving and distribution facilities at the Space Telescope Science Institute

    NASA Astrophysics Data System (ADS)

    Hanisch, Robert J.; Postman, Marc; Pollizzi, Joseph; Richon, J.

    1998-07-01

    The Hubble Data Archive at the Space Telescope Science Institute contains over 4.3 TB of data, primarily for the Hubble Space Telescope, but also from complementary space- based and ground-based facilities. We are in the process of upgrading and generalizing many of the HDA's component system, developing tools to provide more integrated access to the HDA holdings, and working with other major data providing organizations to implement global data location services for astronomy and other space science disciplines. This paper describes the key elements of our archiving and data distribution systems, including a planned transition to DVD media, data compression, data segregation, on-the-fly calibration, an engineering data warehouse, and distributed search and retrieval facilities.

  13. Ripple transport in Helical-Axis Advanced Stellarators: A comparison with classical stellarator/torsatrons

    SciTech Connect

    Beidler, C.D.; Hitchon, W.N.G.

    1995-07-01

    Calculations of the neoclassical transport rates due to particles trapped in the helical ripples of a stellarator`s magnetic field are carried out, based on solutions of the bounceaveraged kinetic equation. These calculations employ a model for the magnetic field strength, B, which is an accurate approximation to the actual B for a wide variety of stellarator-type devices, among which are Helical-Axis Advanced Stellarators (Helias) as well as conventional stellarators and torsatrons. Comparisons are carried out in which it is shown that the Helias concept leads to significant reductions in neoclassical transport rates throughout the entire long-mean-free-path regime, with the reduction being particularly dramatic in the {nu}{sup {minus}1} regime. These findings are confirmed by numerical simulations. Further, it is shown that the behavior of deeply trapped particles in Helias can be fundamentally different from that in classical stellarator/torsatrons; as a consequence, the beneficial effects of a radial electric field on the transport make themselves felt at lower collision frequency than is usual.

  14. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Program review

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This report summarizes the Integrated Application of Active Controls (IAAC) Technology to an Advanced Subsonic Transport Project, established as one element of the NASA/Boeing Energy Efficient Transport Technology Program. The performance assessment showed that incorporating ACT into an airplane designed to fly approximately 200 passengers approximately 2,000 nmi could yield block fuel savings from 6 to 10 percent at the design range. The principal risks associated with incorporating these active control functions into a commercial airplane are those involved with the ACT system implementation. The Test and Evaluation phase of the IAAC Project focused on the design, fabrication, and test of a system that implemented pitch axis fly-by-wire, pitch axis augmentation, and wing load alleviation. The system was built to be flight worthy, and was planned to be experimentally flown on the 757. The system was installed in the Boeing Digital Avionics Flight Controls Laboratory (DAFCL), where open loop hardware and software tests, and a brief examination of a direct drive valve (DDV) actuation concept were accomplished. The IAAC Project has shown that ACT can be beneficially incorporated into a commercial transport airplane. Based on the results achieved during the testing phase, there appears to be no fundamental reason(s) that would preclude the commercial application of ACT, assuming an appropriate development effort is included.

  15. An investigation of air transportation technology at the Massachusetts Institute of Technology, 1990-1991

    NASA Technical Reports Server (NTRS)

    Simpson, Robert W.

    1991-01-01

    Brief summaries are given of research activities at the Massachusetts Institute of Technology (MIT) under the sponsorship of the FAA/NASA Joint University Program. Topics covered include hazard assessment and cockpit presentation issues for microburst alerting systems; the situational awareness effect of automated air traffic control (ATC) datalink clearance amendments; a graphical simulation system for adaptive, automated approach spacing; an expert system for temporal planning with application to runway configuration management; deterministic multi-zone ice accretion modeling; alert generation and cockpit presentation for an integrated microburst alerting system; and passive infrared ice detection for helicopter applications.

  16. Investigation of air transportation technology at Massachusetts Institute of Technology, 1986

    NASA Technical Reports Server (NTRS)

    Simpson, Robert W.

    1988-01-01

    There were three areas of research sponsored in the Flight Transportation Lab. at MIT under the Joint University Research Program during 1986. The first was the completion of efforts investigating the possibility of using Loran-C for final approach guidance to a runway; the second is a preliminary exploration of the application of automated speech recognition in Air Traffic Control; the third is a continuation of a series of research topics into aircraft icing problems.

  17. Interactive multimedia service platform using the ATM transport engine for business and institutional communities

    NASA Astrophysics Data System (ADS)

    Roh, Jangrai; Kim, Jongwon; Hong, Han K.; Kook, Kyoungmook

    1996-01-01

    This paper describes the architecture of an interactive multimedia service platform in addition to implementation techniques based on the ATM transport engine under consideration. To support the interactive multimedia service, office environments need to integrate retrieval, on- demand, communicative, messaging and transactional capabilities into multi-homed hosts and heterogeneous infrastructures. Especially the various over ATM' and service provisioning mechanisms have to be considered in an evolutionary view of the platform.

  18. Multi-Institutional Phase II Clinical Study of Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer in East and Southeast Asia

    SciTech Connect

    Kato, Shingo; Ohno, Tatsuya; Thephamongkhol, Kullathorn; Chansilpa, Yaowalak

    2010-07-01

    Purpose: To evaluate the toxicity and efficacy of concurrent chemoradiotherapy using weekly cisplatin for patients with locally advanced cervical cancer in East and Southeast Asia, a multi-institutional Phase II clinical study was conducted among eight Asian countries. Methods and Materials: Between April 2003 and March 2006, 120 patients (60 with bulky Stage IIB and 60 with Stage IIIB) with previously untreated squamous cell carcinoma of the cervix were enrolled in the present study. Radiotherapy consisted of pelvic external beam radiotherapy (total dose, 50 Gy) and either high-dose-rate or low-dose-rate intracavitary brachytherapy according to institutional practice. The planned Point A dose was 24-28 Gy in four fractions for high-dose-rate-intracavitary brachytherapy and 40-45 Gy in one to two fractions for low-dose-rate-intracavitary brachytherapy. Five cycles of weekly cisplatin (40 mg/m{sup 2}) were administered during the radiotherapy course. Results: All patients were eligible for the study. The median follow-up was 27.3 months. Of the 120 patients, 100 (83%) received four or five cycles of chemotherapy. Acute Grade 3 leukopenia was observed in 21% of the patients, and Grade 3 gastrointestinal toxicity was observed in 6%. No patient failed to complete the radiotherapy course because of toxicity. The 2-year local control and overall survival rate for all patients was 87.1% and 79.6%, respectively. The 2-year major late rectal and bladder complication rate was 2.5% and 0%, respectively. Conclusion: The results have suggested that concurrent chemoradiotherapy using weekly cisplatin is feasible and effective for patients with locally advanced cervical cancer in East and Southeast Asia.

  19. National Institute of Environmental Health Sciences: 50 Years of Advancing Science and Improving Lung Health.

    PubMed

    Antony, Veena B; Redlich, Carrie A; Pinkerton, Kent E; Balmes, John; Harkema, Jack R

    2016-11-15

    The American Thoracic Society celebrates the 50th anniversary of the National Institute of Environmental Health Sciences (NIEHS). The NIEHS has had enormous impact through its focus on research, training, and translational science on lung health. It has been an advocate for clean air both in the United States and across the world. The cutting-edge science funded by the NIEHS has led to major discoveries that have broadened our understanding of the pathogenesis and treatment for lung disease. Importantly, the NIEHS has developed and fostered mechanisms that require cross-cutting science across the spectrum of areas of inquiry, bringing together environmental and social scientists with clinicians to bring their expertise on specific areas of investigation. The intramural program of the NIEHS nurtures cutting-edge science, and the extramural program encourages investigator-initiated research while at the same time providing broader direction through important initiatives. Under the umbrella of the NIEHS and guided by Dr. Linda Birnbaum, the director of the NIEHS, important collaborative programs, such as the Superfund Program and the National Toxicology Program, work to discover mechanisms to protect from environmental toxins. The American Thoracic Society has overlapping goals with the NIEHS, and the strategic plans of both august bodies converge to synergize on population lung health. These bonds must be tightened and highlighted as we work toward our common goals.

  20. National Institutes of Health: a catalyst in advancing regenerative medicine science into practice.

    PubMed

    Rao, Mahendra

    2015-05-01

    The stem cell domain of the regenerative medicine field has seen fundamental changes initiated by seminal discoveries in cell biology, genetic engineering, and whole genome sequencing. Many of these discoveries were funded in part by the National Institutes of Health (NIH), and the NIH remains a leader in supporting research in the United States. However, as the field has developed, the NIH has responded proactively to identify roadblocks and to develop solutions that will accelerate translation of basic discoveries to the clinical setting. These activities range from organizing specialized workshops and coordinating activities among international organizations and the different arms of the government to funding small-scale industry. In addition, the NIH has been a key driver in providing needed infrastructure in areas in which the private sector has been unable to, or does not believe it can, invest. These activities of the NIH are as important as its traditional funding role, and I believe they have contributed to the innovation and rapid pace of discovery in this field.

  1. Sunitinib treatment in patients with advanced renal cell cancer: the Brazilian National Cancer Institute (INCA) experience

    PubMed Central

    Coelho, Rafael Corrêa; Reinert, Tomás; Campos, Franz; Peixoto, Fábio Affonso; de Andrade, Carlos Augusto; Castro, Thalita; Herchenhorn, Daniel

    2016-01-01

    ABSTRACT Purpose: The aim of this study was to assess the impact of sunitinib treatment in a non-screened group of patients with metastatic renal cell cancer (mRCC) treated by the Brazilian Unified Health System (SUS) at a single reference institution. Material and Methods: Retrospective cohort study, which evaluated patients with mRCC who received sunitinib between May 2010 and December 2013. Results: Fifty-eight patients were eligible. Most patients were male 41 (71%), with a median age of 58 years. Nephrectomy was performed in 41 (71%) patients with a median interval of 16 months between the surgery and initiation of sunitinib. The most prevalent histological subtype was clear cell carcinoma, present in 52 (91.2%) patients. In 50 patients (86%), sunitinib was the first line of systemic treatment. The main adverse effects were fatigue (57%), hypothyroidism (43%), mucositis (33%) and diarrhea (29%). Grade 3 and 4 adverse effects were infrequent: fatigue (12%), hypertension (12%), thrombocytopenia (7%), neutropenia (5%) and hand-foot syndrome (5%). Forty percent of patients achieved a partial response and 35% stable disease, with a disease control rate of 75%. Median progression free survival was 7.6 months and median overall survival was 14.1 months. Conclusion: Sunitinib treatment was active in the majority of patients, especially those with low and intermediate risk by MSKCC score, with manageable toxicity. Survival rates were inferior in this non-screened population with mRCC treated in the SUS. PMID:27564279

  2. Institute for Advanced Education in Geospatial Sciences Educating the Next Generation of Scientists

    NASA Technical Reports Server (NTRS)

    Lawhead, Pamela; Johnson, Jay

    2003-01-01

    The project, as stated earlier is sponsored by NASA and is located at the University of Mississippi in Oxford, MS. It has two principal investigators with one of them, Pam Lawhead, serving as the Director of the Institute. The goal of the project is to create fifty online courses in Remote Sensing over the five year life of the project. Each year ten courses are put out for bid and the best ten submissions are accepted. This request for proposals insures that the course creators are content experts. Equivalence of product drives the online hosting of the courses. That is, we want the online presentation and delivery of each course to be as multi-media intensive as is effective. The goal is not to replace existing courses but, to provide courses created by content experts to as many colleges and universities as possible. This effort to create and host online courses has as its final goal the creation of a very large college educated workforce prepared to use the vast stores of information gathers by NASA and other remote sensing industries to enhance life on this planet.

  3. 41 CFR 302-10.300 - May I receive an advance of funds when a commercial carrier transports the mobile home?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false May I receive an advance of funds when a commercial carrier transports the mobile home? 302-10.300 Section 302-10.300 Public... Advance of Funds § 302-10.300 May I receive an advance of funds when a commercial carrier transports...

  4. An investigation of air transportation technology at the Massachusetts Institute of Technology, 1991-1992

    NASA Technical Reports Server (NTRS)

    Simpson, Robert W.

    1993-01-01

    There are two completed projects and five new or continuing research activities under the sponsorship of the FAA/NASA Joint University Program as the 1991-92 period ends. A brief summary of some of the continuing research projects is provided. The active research projects are: (1) extensions for the FASA (Final Approach Spacing Advisory) System; (2) radar tracking around a turn; (3) impact of advanced technologies of single pilot IFR operations; (4) system and human limitations in millimeter wave and infrared synthetic vision systems; and (5) differences in party line information usage by operational user groups.

  5. Can the Institute of Medicine trump the dominant logic of nursing? Leading change in advanced practice education.

    PubMed

    Dreher, Melanie C; Clinton, Patricia; Sperhac, Arlene

    2014-01-01

    The Institute of Medicine (IOM; 2010) has called for a transformation of the nursing profession to lead the redesign of health care in the United States. It acknowledges the need for profound change in nursing education, particularly advanced practice education, to produce the next generation of leaders in sufficient quantity to expand access, improve quality, and reduce cost. Although the IOM provides welcome validation of nursing's significant role, most of the recommendations are not new and have been advocated by nurse educators for decades. What has prevented us from creating the nimble and responsive educational programs that would ensure a sufficient corpus of advanced practice nurses with the relevant knowledge and skill to transform our ailing health system? Conceptualizing nursing as a complex, adaptive system (J.W. Begun and K. White, 1997), this article explores three examples of the dominant logic, grounded in a historical legacy that has kept the nursing profession from realizing its promise as a potent force: (a) the continuing preference for experience over education, (b) the belief that only nurses can teach nurses, and (c) the hegemony of the research doctorate.

  6. Phase 2 Multi-institutional Trial Evaluating Gemcitabine and Stereotactic Body Radiotherapy for Patients With Locally Advanced Unresectable Pancreatic Adenocarcinoma

    PubMed Central

    Herman, Joseph M; Chang, Daniel T; Goodman, Karyn A; Dholakia, Avani S; Raman, Siva P; Hacker-Prietz, Amy; Iacobuzio-Donahue, Christine A; Griffith, Mary E; Pawlik, Timothy M; Pai, Jonathan S; O'Reilly, Eileen; Fisher, George A; Wild, Aaron T; Rosati, Lauren M; Zheng, Lei; Wolfgang, Christopher L; Laheru, Daniel A; Columbo, Laurie A; Sugar, Elizabeth A; Koong, Albert C

    2015-01-01

    Background This phase 2 multi-institutional study was designed to determine whether gemcitabine (GEM) with fractionated stereotactic body radiotherapy (SBRT) results in acceptable late grade 2 to 4 gastrointestinal toxicity when compared with a prior trial of GEM with single-fraction SBRT in patients with locally advanced pancreatic cancer (LAPC). Methods A total of 49 patients with LAPC received up to 3 doses of GEM (1000 mg/m2) followed by a 1-week break and SBRT (33.0 gray [Gy] in 5 fractions). After SBRT, patients continued to receive GEM until disease progression or toxicity. Toxicity was assessed using the National Cancer Institute Common Terminology Criteria for Adverse Events [version 4.0] and the Radiation Therapy Oncology Group radiation morbidity scoring criteria. Patients completed the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) and pancreatic cancer-specific QLQ-PAN26 module before SBRT and at 4 weeks and 4 months after SBRT. Results The median follow-up was 13.9 months (range, 3.9-45.2 months). The median age of the patients was 67 years and 84% had tumors of the pancreatic head. Rates of acute and late (primary endpoint) grade ≥2 gastritis, fistula, enteritis, or ulcer toxicities were 2% and 11%, respectively. QLQ-C30 global quality of life scores remained stable from baseline to after SBRT (67 at baseline, median change of 0 at both follow-ups; P>.05 for both). Patients reported a significant improvement in pancreatic pain (P = .001) 4 weeks after SBRT on the QLQ-PAN26 questionnaire. The median plasma carbohydrate antigen 19-9 (CA 19-9) level was reduced after SBRT (median time after SBRT, 4.2 weeks; 220 U/mL vs 62 U/mL [P<.001]). The median overall survival was 13.9 months (95% confidence interval, 10.2 months-16.7 months). Freedom from local disease progression at 1 year was 78%. Four patients (8%) underwent margin-negative and lymph node-negative surgical resections. Conclusions

  7. Affordable In-Space Transportation. Phase 2; An Advanced Concepts Project

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Affordable In-Space Transportation (AIST) program was established by the NASA Office of Space Access to improve transportation and lower the costs from Low Earth Orbit (LEO) to Geostationary Earth Orbit (GEO) and beyond (to Lunar orbit, Mars orbit, inner solar system missions, and return to LEO). A goal was established to identify and develop radically innovative concepts for new upper stages for Reusable Launch Vehicles (RLV) and Highly Reusable Space Transportation (HRST) systems. New architectures and technologies are being identified which have the potential to meet a cost goal of $1,000 to $2,000 per pound for transportation to GEO and beyond for overall mission cost (including the cost to LEO). A Technical Interchange Meeting (ITM) was held on October 16 and 17, 1996 in Huntsville, Alabama to review previous studies, present advanced concepts and review technologies that could be used to meet the stated goals. The TIM was managed by NASA-Mar-shaU Space Flight Center (MSFC) Advanced Concepts Office with Mr. Alan Adams providing TIM coordination. Mr. John C. Manidns of NASA Headquarters provided overall sponsorship. The University of Alabama in Huntsville (UAH) Propulsion Research Center hosted the TM at the UAH Research Center. Dr. Clark Hawk, Center Director, was the principal investigator. Technical support was provided by Christensen Associates. Approximately 70 attendees were present at the meeting. This Executive Summary provides a record of the key discussions and results of the TIM in a summary format. It incorporates the response to the following basic issues of the TPA, which addressed the following questions: 1. What are the cost drivers and how can they be reduced? 2. What are the operational issues and their impact on cost? What is the current Technology Readiness Level (TRL) and what will it take to reach TRL 6? 4. What are the key enabling technologies and sequence for their accomplishment? 5. What is the proposed implementation time frame

  8. Affordable In-Space Transportation Phase 2: An Advanced Concepts Project

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Affordable In-Space Transportation (AIST) program was established by the NASA Office of Space Access to improve transportation and lower the costs from Low Earth Orbit (LEO) to Geostationary Earth Orbit (GEO) and beyond (to Lunar orbit, Mars orbit, inner solar system missions, and return to LEO). A goal was established to identify and develop radically innovative concepts for new upper stages for Reusable Launch Vehicles (RLV) and Highly Reusable Space Transportation (HRST) systems. New architectures and technologies are being identified which have the potential to meet a cost goal of $1,000 to $2,000 per pound for transportation to GEO and beyond for overall mission cost (including the cost to LEO). A Technical Interchange Meeting (TTM) was held on October 16 and 17, 1996 in Huntsville, Alabama to review previous studies, present advanced concepts and review technologies that could be used to meet the stated goals. The TIN4 was managed by NASA-Marshall Space Flight Center (MSFC) Advanced Concepts Office with Mr. Alan Adams providing TIM coordination. Mr. John C. Mankins of NASA Headquarters provided overall sponsorship. The University of Alabama in Huntsville (UAH) Propulsion Research Center hosted the TIM at the UAH Research Center. Dr. Clark Hawk, Center Director, was the principal investigator. Technical support was provided by Christensen Associates. Approximately 70 attendees were present at the meeting. This Executive Summary provides a record of the key discussions and results of the TIN4 in a summary for-mat. It incorporates the response to the following basic issues of the TDVL which addressed the following questions: 1. What are the cost drivers and how can they be reduced? 2. What are the operational issues and their impact on cost? 3. What is the current technology readiness level (TRL) and what will it take to reach TRL 6? 4. What are the key enabling technologies and sequence for their accomplishment? 5 . What is the proposed implementation time

  9. [A study of the transport of three dimensional medical images to remote institutions for telediagnosis].

    PubMed

    Hayashi, Takashi; Iwai, Mitsuhiro; Takahashi, Katsuhiko; Takeda, Satoshi; Tateishi, Toshiki; Kaneko, Rumi; Ogasawara, Yoko; Yonezawa, Kazuya; Hanada, Akiko

    2011-01-01

    Using a 3D-imaging-create-function server and network services by IP-VPN, we began to deliver 3D images to the remote institution. An indication trial of the primary image, a rotary trial of a 3D image, and a reproducibility trial were studied in order to examine the practicality of using the system in a real network between Hakodate and Sapporo (communication distance of about 150 km). In these trials, basic data (time and receiving data volume) were measured for every variation of QF (quality factor) or monitor resolution. Analyzing the results of the system using a 3D image delivery server of our hospital with variations in the setting of QF and monitor resolutions, we concluded that this system has practicality in the remote interpretation-of-radiogram work, even if the access point of the region has a line speed of 6 Mbps.

  10. A Single-institution Experience with Open Irreversible Electroporation for Locally Advanced Pancreatic Carcinoma

    PubMed Central

    Yan, Li; Chen, Yong-Liang; Su, Ming; Liu, Tian; Xu, Kai; Liang, Feng; Gu, Wan-Qing; Lu, Shi-Chun

    2016-01-01

    Background: Locally advanced pancreatic carcinoma (LAPC) is characterized by poor prognosis despite recommended concurrent chemoradiotherapy. Irreversible electroporation (IRE) has emerged as a potential option for the management of unresectable pancreatic cancer. This study was conducted to evaluate the safety and short-term efficacy of open IRE for the treatment of LAPC. Methods: Retrospective data of 25 consecutive patients receiving IRE for T3 lesions from July 2015 to June 2016 at a single center were analyzed. The perioperative and long-term IRE-related complications were reviewed to evaluate the safety of the procedure. The tumor reduction and biological response were analyzed through computed tomography/magnetic resonance imaging; the serum level of CA19-9 was measured as a secondary endpoint to evaluate the short-term efficacy of IRE. Results: All patients were successfully treated; the median tumor size was 4.2 cm and the median IRE time was 36 min. Four intraoperative procedure-related complications were observed (16%): two transient hypertensive episodes, one hypotension case, and one transient supraventricular tachycardia case. Nine postoperative complications were described, including three Grade A pancreatic fistulas, three delayed gastric emptying, one acute pancreatitis, one upper gastrointestinal hemorrhage, and one portal vein thrombosis. The overall rate of stable disease was 28%, 36% achieved partial response, and lower serum CA19-9 levels were recorded in all patients at discharge. Conclusions: IRE is feasible for the treatment of LAPC and is a reasonable intervention strategy owing to its combined attributes of safety and efficacy. PMID:27958223

  11. A Psychoacoustic Evaluation of Noise Signatures from Advanced Civil Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Rizzi, Stephen A.; Christian, Andrew

    2016-01-01

    The NASA Environmentally Responsible Aviation project has been successful in developing and demonstrating technologies for integrated aircraft systems that can simultaneously meet aggressive goals for fuel burn, noise and emissions. Some of the resulting systems substantially differ from the familiar tube and wing designs constituting the current civil transport fleet. This study attempts to explore whether or not the effective perceived noise level metric used in the NASA noise goal accurately reflects human subject response across the range of vehicles considered. Further, it seeks to determine, in a quantitative manner, if the sounds associated with the advanced aircraft are more or less preferable to the reference vehicles beyond any differences revealed by the metric. These explorations are made through psychoacoustic tests in a controlled laboratory environment using simulated stimuli developed from auralizations of selected vehicles based on systems noise assessments.

  12. Design and fabrication of brazed Rene 41 honeycomb sandwich structural panels for advanced space transportation systems

    NASA Technical Reports Server (NTRS)

    Hepler, A. K.; Swegle, A. R.

    1981-01-01

    The design and fabrication of two large brazed Rene 41 honeycomb panels, the establishment of a test plan, the design and fabrication of a test fixture to subject the panels to cyclic thermal gradients and mechanical loads equivalent to those imposed on an advanced space transportation vehicle during its boost and entry trajectories are discussed. The panels will be supported at four points, creating three spans. The outer spans are 45.7 cm (18 in.) and the center span 76.2 cm (30 in). Specimen width is 30.5 cm (12 in.). The panels were primarily designed by boost conditions simulated by subjecting the panels to liquid nitrogen, 77K (-320 F) on one side and 455K (360 F) on the other side and by mechanically imposing loads representing vehicle fuel pressure loads. Entry conditions were simulated by radiant heating to 1034K (1400 F). The test program subjected the panels to 500 boost thermal conditions. Results are presented.

  13. Applicability of the control configured design approach to advanced earth orbital transportation systems

    NASA Technical Reports Server (NTRS)

    Hepler, A. K.; Zeck, H.; Walker, W. H.; Shafer, D. E.

    1978-01-01

    The applicability of the control configured design approach (CCV) to advanced earth orbital transportation systems was studied. The baseline system investigated was fully reusable vertical take-off/horizontal landing single-stage-to-orbit vehicle and had mission requirements similar to the space shuttle orbiter. Technical analyses were made to determine aerodynamic, flight control and subsystem design characteristics. Figures of merit were assessed on vehicle dry weight and orbital payload. The results indicated that the major parameters for CCV designs are hypersonic trim, aft center of gravity, and control surface heating. Optimized CCV designs can be controllable and provide substantial payload gains over conventional non-CCV design vertical take-off vehicles.

  14. Ejector nozzle test results at simulated flight conditions for an advanced supersonic transport propulsion system

    NASA Technical Reports Server (NTRS)

    Nelson, D. P.; Bresnahan, D. L.

    1983-01-01

    Results are presented of wind tunnel tests conducted to verify the performance improvements of a refined ejector nozzle design for advanced supersonic transport propulsion systems. The analysis of results obtained at simulated engine operating conditions is emphasized. Tests were conducted with models of approximately 1/10th scale which were configured to simulate nozzle operation at takeoff, subsonic cruise, transonic cruise, and supersonic cruise. Transonic cruise operation was not a consideration during the nozzle design phase, although an evaluation at this condition was later conducted. Test results, characterized by thrust and flow coefficients, are given for a range of nozzle pressure ratios, emphasizing the thrust performance at the engine operating conditions predicted for each flight Mach number. The results indicate that nozzle performance goals were met or closely approximated at takeoff and supersonic cruise, while subsonic cruise performance was within 2.3 percent of the goal with further improvement possible.

  15. Plant chromium uptake and transport, physiological effects and recent advances in molecular investigations.

    PubMed

    Gomes, Maria Angélica da Conceição; Hauser-Davis, Rachel Ann; Suzuki, Marina Satika; Vitória, Angela Pierre

    2017-06-01

    Increasingly, anthropogenic perturbations of the biosphere manifest in a broad array of global phenomena, causing widespread contamination of most ecosystems, with high dispersion rates of many contaminants throughout different environmental compartments, including metals. Chromium (Cr) contamination in particular, is, increasingly, posing a serious threat to the environment, emerging as a major health hazard to the biota. However, although the molecular and physiological mechanisms of plant responses to many heavy metals, especially lead (Pb) and cadmium (Cd), have been focused upon in recent years, chromium has attracted significantly less attention. In this context, this review discusses aspects of Cr uptake and transport, some physiological and biochemical effects of Cr exposure in plants, and molecular defense mechanisms against this metal. Recent advances in determining these responses, in fields of knowledge such as genomics, proteomics and metallomics, are discussed herein.

  16. Analysis and Preliminary Design of an Advanced Technology Transport Flight Control System

    NASA Technical Reports Server (NTRS)

    Frazzini, R.; Vaughn, D.

    1975-01-01

    The analysis and preliminary design of an advanced technology transport aircraft flight control system using avionics and flight control concepts appropriate to the 1980-1985 time period are discussed. Specifically, the techniques and requirements of the flight control system were established, a number of candidate configurations were defined, and an evaluation of these configurations was performed to establish a recommended approach. Candidate configurations based on redundant integration of various sensor types, computational methods, servo actuator arrangements and data-transfer techniques were defined to the functional module and piece-part level. Life-cycle costs, for the flight control configurations, as determined in an operational environment model for 200 aircraft over a 15-year service life, were the basis of the optimum configuration selection tradeoff. The recommended system concept is a quad digital computer configuration utilizing a small microprocessor for input/output control, a hexad skewed set of conventional sensors for body rate and body acceleration, and triple integrated actuators.

  17. Space Shuttle 2 Advanced Space Transportation System. Volume 1: Executive Summary

    NASA Technical Reports Server (NTRS)

    Adinaro, James N.; Benefield, Philip A.; Johnson, Shelby D.; Knight, Lisa K.

    1989-01-01

    An investigation into the feasibility of establishing a second generation space transportation system is summarized. Incorporating successful systems from the Space Shuttle and technological advances made since its conception, the second generation shuttle was designed to be a lower-cost, reliable system which would guarantee access to space well into the next century. A fully reusable, all-liquid propellant booster/orbiter combination using parallel burn was selected as the base configuration. Vehicle characteristics were determined from NASA ground rules and optimization evaluations. The launch profile was constructed from particulars of the vehicle design and known orbital requirements. A stability and control analysis was performed for the landing phase of the orbiter's flight. Finally, a preliminary safety analysis was performed to indicate possible failure modes and consequences.

  18. Performance potential of an advanced technology Mach 3 turbojet engine installed on a conceptual high-speed civil transport

    NASA Technical Reports Server (NTRS)

    Morris, Shelby J., Jr.; Geiselhart, Karl A.; Coen, Peter G.

    1989-01-01

    The performance of an advanced technology conceptual turbojet optimized for a high-speed civil aircraft is presented. This information represents an estimate of performance of a Mach 3 Brayton (gas turbine) cycle engine optimized for minimum fuel burned at supersonic cruise. This conceptual engine had no noise or environmental constraints imposed upon it. The purpose of this data is to define an upper boundary on the propulsion performance for a conceptual commercial Mach 3 transport design. A comparison is presented demonstrating the impact of the technology proposed for this conceptual engine on the weight and other characteristics of a proposed high-speed civil transport. This comparison indicates that the advanced technology turbojet described could reduce the gross weight of a hypothetical Mach 3 high-speed civil transport design from about 714,000 pounds to about 545,000 pounds. The aircraft with the baseline engine and the aircraft with the advanced technology engine are described.

  19. Analysis of Turbofan Design Options for an Advanced Single-Aisle Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Guynn, Mark D.; Berton, Jeffrey J.; Fisher, Kenneth L.; Haller, William J.; Tong, Michael T.; Thurman, Douglas R.

    2009-01-01

    The desire for higher engine efficiency has resulted in the evolution of aircraft gas turbine engines from turbojets, to low bypass ratio, first generation turbofans, to today's high bypass ratio turbofans. It is possible that future designs will continue this trend, leading to very-high or ultra-high bypass ratio (UHB) engines. Although increased bypass ratio has clear benefits in terms of propulsion system metrics such as specific fuel consumption, these benefits may not translate into aircraft system level benefits due to integration penalties. In this study, the design trade space for advanced turbofan engines applied to a single-aisle transport (737/A320 class aircraft) is explored. The benefits of increased bypass ratio and associated enabling technologies such as geared fan drive are found to depend on the primary metrics of interest. For example, bypass ratios at which fuel consumption is minimized may not require geared fan technology. However, geared fan drive does enable higher bypass ratio designs which result in lower noise. Regardless of the engine architecture chosen, the results of this study indicate the potential for the advanced aircraft to realize substantial improvements in fuel efficiency, emissions, and noise compared to the current vehicles in this size class.

  20. Refined Exploration of Turbofan Design Options for an Advanced Single-Aisle Transport

    NASA Technical Reports Server (NTRS)

    Guynn, Mark D.; Berton, Jeffrey J.; Fisher, Kenneth L.; Haller, William J.; Tong, Michael T.; Thurman, Douglas R.

    2011-01-01

    A comprehensive exploration of the turbofan engine design space for an advanced technology single-aisle transport (737/A320 class aircraft) was conducted previously by the authors and is documented in a prior report. Through the course of that study and in a subsequent evaluation of the approach and results, a number of enhancements to the engine design ground rules and assumptions were identified. A follow-on effort was initiated to investigate the impacts of these changes on the original study results. The fundamental conclusions of the prior study were found to still be valid with the revised engine designs. The most significant impact of the design changes was a reduction in the aircraft weight and block fuel penalties incurred with low fan pressure ratio, ultra-high bypass ratio designs. This enables lower noise levels to be pursued (through lower fan pressure ratio) with minor negative impacts on aircraft weight and fuel efficiency. Regardless of the engine design selected, the results of this study indicate the potential for the advanced aircraft to realize substantial improvements in fuel efficiency, emissions, and noise compared to the current vehicles in this size class.

  1. Proceedings of the Advanced Seminar on one-dimensional, open-channel Flow and transport modeling

    USGS Publications Warehouse

    Schaffranek, Raymond W.

    1989-01-01

    In view of the increased use of mathematical/numerical simulation models, of the diversity of both model investigations and informational project objectives, and of the technical demands of complex model applications by U.S. Geological Survey personnel, an advanced seminar on one-dimensional open-channel flow and transport modeling was organized and held on June 15-18, 1987, at the National Space Technology Laboratory, Bay St. Louis, Mississippi. Principal emphasis in the Seminar was on one-dimensional flow and transport model-implementation techniques, operational practices, and application considerations. The purposes of the Seminar were to provide a forum for the exchange of information, knowledge, and experience among model users, as well as to identify immediate and future needs with respect to model development and enhancement, user support, training requirements, and technology transfer. The Seminar program consisted of a mix of topical and project presentations by Geological Survey personnel. This report is a compilation of short papers that summarize the presentations made at the Seminar.

  2. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The Current and Advanced Technology ACT control system definition tasks of the Integrated Application of Active Controls (IAAC) Technology project within the Energy Efficient Transport Program are summarized. The systems mechanize six active control functions: (1) pitch augmented stability; (2) angle of attack limiting; (3) lateral/directional augmented stability; (4) gust load alleviation; (5) maneuver load control; and (6) flutter mode control. The redundant digital control systems meet all function requirements with required reliability and declining weight and cost as advanced technology is introduced.

  3. The Advanced Re-Entry Vehicle (ARV) a Development Step from ATV Toward Manned Transportation Systems

    NASA Astrophysics Data System (ADS)

    Bottacini, M.; Berthe, P.; Vo, X.; Pietsch, K.

    2011-08-01

    The Advanced Re-entry Vehicle (ARV) programme has been undertaken by Europe with the objective to contribute to the preparation of a future European crew transportation system, while providing a valuable logistic support to the ISS through an operational cargo return system. This development would allow: - the early acquisition of critical technologies; - the design, development and testing of elements suitable for the follow up human rated transportation system. These vehicles should also serve future LEO infrastructures and exploration missions. With the aim to satisfy the above objectives a team composed by major European industries and led by EADS Astrium Space Transportation is currently conducting the phase A of the programme under contract with the European Space Agency (ESA). Two vehicle versions are being investigated: a Cargo version, transporting cargo only to/from the ISS, and a Crew version, which will allow the transfer of both crew and cargo to/from the ISS. The ARV Cargo version, in its present configuration, is composed of three modules. The Versatile Service Module (VSM) provides to the system the propulsion/GNC for orbital manoeuvres and attitude control and the orbital power generation. Its propulsion system and GNC shall be robust enough to allow its use for different launch stacks and different LEO missions in the future. The Un-pressurised Cargo Module (UCM) provides the accommodation for about 3000 kg of un-pressurised cargo and is to be sufficiently flexible to ensure the transportation of: - orbital infrastructure components (ORU's); - scientific / technological experiments; - propellant for re-fuelling, re-boost (and deorbiting) of the ISS. The Re-entry Module (RM) provides a pressurized volume to accommodate active/passive cargo (2000 kg upload/1500 kg download). It is conceived as an expendable conical capsule with spherical heat- hield, interfacing with the new docking standard of the ISS, i.e. it carries the IBDM docking system, on a

  4. The Advanced Re-Entry Vehicle (ARV) A Development Step From ATV Toward Manned Transportation Systems

    NASA Astrophysics Data System (ADS)

    Bottacini, Massimiliano; Berthe, Philippe; Vo, Xavier; Pietsch, Klaus

    2011-05-01

    The Advanced Re-entry Vehicle (ARV) programme has been undertaken by Europe with the objective to contribute to the preparation of a future European crew transportation system, while providing a valuable logistic support to the ISS through an operational cargo return system. This development would allow: - the early acquisition of critical technologies; - the design, development and testing of elements suitable for the follow up human rated transportation system. These vehicles should also serve future LEO infrastructures and exploration missions. With the aim to satisfy the above objectives a team composed by major European industries and led by EADS Astrium Space Transportation is currently conducting the phase A of the programme under contract with the European Space Agency (ESA). Two vehicle versions are being investigated: a Cargo version, transporting cargo only to/from the ISS, and a Crew version, which will allow the transfer of both crew and cargo to/from the ISS. The ARV Cargo version, in its present configuration, is composed of three modules. The Versatile Service Module (VSM) provides to the system the propulsion/GNC for orbital manoeuvres and attitude control and the orbital power generation. Its propulsion system and GNC shall be robust enough to allow its use for different launch stacks and different LEO missions in the future. The Un-pressurised Cargo Module (UCM) provides the accommodation for about 3000 kg of unpressurised cargo and is to be sufficiently flexible to ensure the transportation of: - orbital infrastructure components (ORU’s); - scientific / technological experiments; - propellant for re-fuelling, re-boost (and de-orbiting) of the ISS. The Re-entry Module (RM) provides a pressurized volume to accommodate active/passive cargo (2000 kg upload/1500 kg download). It is conceived as an expendable conical capsule with spherical heat-shield, interfacing with the new docking standard of the ISS, i.e. it carries the IBDM docking system, on

  5. High-Purity Aluminum Magnet Technology for Advanced Space Transportation Systems

    NASA Technical Reports Server (NTRS)

    Goodrich, R. G.; Pullam, B.; Rickle, D.; Litchford, R. J.; Robertson, G. A.; Schmidt, D. D.; Cole, John (Technical Monitor)

    2001-01-01

    Basic research on advanced plasma-based propulsion systems is routinely focused on plasmadynamics, performance, and efficiency aspects while relegating the development of critical enabling technologies, such as flight-weight magnets, to follow-on development work. Unfortunately, the low technology readiness levels (TRLs) associated with critical enabling technologies tend to be perceived as an indicator of high technical risk, and this, in turn, hampers the acceptance of advanced system architectures for flight development. Consequently, there is growing recognition that applied research on the critical enabling technologies needs to be conducted hand in hand with basic research activities. The development of flight-weight magnet technology, for example, is one area of applied research having broad crosscutting applications to a number of advanced propulsion system architectures. Therefore, NASA Marshall Space Flight Center, Louisiana State University (LSU), and the National High Magnetic Field Laboratory (NHMFL) have initiated an applied research project aimed at advancing the TRL of flight-weight magnets. This Technical Publication reports on the group's initial effort to demonstrate the feasibility of cryogenic high-purity aluminum magnet technology and describes the design, construction, and testing of a 6-in-diameter by 12-in-long aluminum solenoid magnet. The coil was constructed in the machine shop of the Department of Physics and Astronomy at LSU and testing was conducted in NHMFL facilities at Florida State University and at Los Alamos National Laboratory. The solenoid magnet was first wound, reinforced, potted in high thermal conductivity epoxy, and bench tested in the LSU laboratories. A cryogenic container for operation at 77 K was also constructed and mated to the solenoid. The coil was then taken to NHMFL facilities in Tallahassee, FL. where its magnetoresistance was measured in a 77 K environment under steady magnetic fields as high as 10 T. In

  6. Colleges and Institutes: Advanced Skills and Applied Research. Submission to the House of Commons Standing Committee on Finance Pre-Budget Consultations 2009

    ERIC Educational Resources Information Center

    Association of Canadian Community Colleges, 2009

    2009-01-01

    Integrated with the industrial and technical drivers of the economy, Canada's colleges, institutes, polytechnics and cegeps offer the advanced skills of faculty and staff to support the private sector's need for applied research, product and process innovation, commercialization and technology transfer. Federal investments in research over the…

  7. Black Economic Advancement in the New Millennium: Globalization, Education, and Technology. Special Report: National Policy Institute (8th, Washington, DC, January 20-22, 2000).

    ERIC Educational Resources Information Center

    Focus, 2000

    2000-01-01

    This special issue presents, in capsule form, presentations from workshops at the Eighth National Policy Institute. The conference theme of black economic advancement in the new century focused on globalization, education, and technology. Ten workshops were the core of the conference, and their topics were: (1) overcoming the 2000 Census…

  8. The combination of docetaxel, cisplatin, and 5-fluorouracil in advanced gastric cancer: a single-institution experience.

    PubMed

    Ben Aharon, Irit; Purim, Ofer; Kundel, Yulia; Brenner, Ronen; Gordon, Noa; Sulkes, Aaron; Brenner, Baruch

    2012-03-01

    The addition of docetaxel to cisplatin and 5-fluorouracil was shown to confer a survival benefit in patients with advanced gastric cancer (one; AGC), although with increased toxicity. We hereby report our experience with the use of docetaxel, cisplatin, and 5-fluorouracil (DCF). Data on all consecutive patients who received first-line treatment with DCF at our institute were analyzed retrospectively. Twenty-three patients were included. The median age was 63 years. Patients received an average of 10 cycles (range, 1-24). All experienced grade ≥3 toxicity, requiring hospitalization in 35%. There was one toxic death. The median progression-free and overall survival rates were 10.0 and 12.8 months, respectively; the 2-year and 3-year survival rates were 22 and 17%, respectively. The DCF regimen is indeed associated with substantial toxicity, although manageable. Nevertheless, the observed benefit was remarkable compared with any previous report on chemotherapy in AGC, and should therefore represent a valid treatment option in AGC and a platform for future combinations.

  9. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study. Volume 2: Appendices

    NASA Technical Reports Server (NTRS)

    Hanks, G. W.; Shomber, H. A.; Dethman, H. A.; Gratzer, L. B.; Maeshiro, A.; Gangsaas, D.; Blight, J. D.; Buchan, S. M.; Crumb, C. B.; Dorwart, R. J.

    1981-01-01

    The current status of the Active Controls Technology (ACT) for the advanced subsonic transport project is investigated through analysis of the systems technical data. Control systems technologies under examination include computerized reliability analysis, pitch axis fly by wire actuator, flaperon actuation system design trade study, control law synthesis and analysis, flutter mode control and gust load alleviation analysis, and implementation of alternative ACT systems. Extensive analysis of the computer techniques involved in each system is included.

  10. PREFACE: Joint IPPP Durham/Cockcroft Institute/ICFA Workshop on Advanced QED methods for Future Accelerators

    NASA Astrophysics Data System (ADS)

    Bailey, I. R.; Barber, D. P.; Chattopadhyay, S.; Hartin, A.; Heinzl, T.; Hesselbach, S.; Moortgat-Pick, G. A.

    2009-11-01

    The joint IPPP Durham/Cockcroft Institute/ICFA workshop on advanced QED methods for future accelerators took place at the Cockcroft Institute in early March 2009. The motivation for the workshop was the need for a detailed consideration of the physics processes associated with beam-beam effects at the interaction points of future high-energy electron-positron colliders. There is a broad consensus within the particle physics community that the next international facility for experimental high-energy physics research beyond the Large Hadron Collider at CERN should be a high-luminosity electron-positron collider working at the TeV energy scale. One important feature of such a collider will be its ability to deliver polarised beams to the interaction point and to provide accurate measurements of the polarisation state during physics collisions. The physics collisions take place in very dense charge bunches in the presence of extremely strong electromagnetic fields of field strength of order of the Schwinger critical field strength of 4.4×1013 Gauss. These intense fields lead to depolarisation processes which need to be thoroughly understood in order to reduce uncertainty in the polarisation state at collision. To that end, this workshop reviewed the formalisms for describing radiative processes and the methods of calculation in the future strong-field environments. These calculations are based on the Furry picture of organising the interaction term of the Lagrangian. The means of deriving the transition probability of the most important of the beam-beam processes - Beamsstrahlung - was reviewed. The workshop was honoured by the presentations of one of the founders, V N Baier, of the 'Operator method' - one means for performing these calculations. Other theoretical methods of performing calculations in the Furry picture, namely those due to A I Nikishov, V I Ritus et al, were reviewed and intense field quantum processes in fields of different form - namely those

  11. A Status of the Advanced Space Transportation Program from Planning to Action

    NASA Technical Reports Server (NTRS)

    Lyles, Garry; Griner, Carolyn

    1998-01-01

    A Technology Plan for Enabling Commercial Space Business was presented at the 48th International Astronautical Congress in Turin, Italy. This paper presents a status of the program's accomplishments. Technology demonstrations have progressed in each of the four elements of the program; (1) Low Cost Technology, (2) Advanced Reusable Technology, (3) Space Transfer Technology and (4) Space Transportation Research. The Low Cost Technology program element is primarily focused at reducing development and acquisition costs of aerospace hardware using a "design to cost" philosophy with robust margins, adapting commercial manufacturing processes and commercial off-the-shelf hardware. The attributes of this philosophy for small payload launch are being demonstrated at the component, sub-system, and system level. The X-34 "Fastrac" engine has progressed through major component and subsystem demonstrations. A propulsion system test bed has been implemented for system-level demonstration of component and subsystem technologies; including propellant tankage and feedlines, controls, pressurization, and engine systems. Low cost turbopump designs, commercial valves and a controller are demonstrating the potential for a ten-fold reduction in engine and propulsion system costs. The Advanced Reusable Technology program element is focused on increasing life through high strength-to-weight structures and propulsion components, highly integrated propellant tanks, automated checkout and health management and increased propulsion system performance. The validation of rocket based combined cycle (RBCC) propulsion is pro,-,ressing through component and subsystem testing. RBCC propulsion has the potential to provide performance margin over an all rocket system that could result in lower gross liftoff weight, a lower propellant mass fraction or a higher payload mass fraction. The Space Transfer Technology element of the program is pursuing technology that can improve performance and

  12. A simulation study of crew performance in operating an advanced transport aircraft in an automated terminal area environment

    NASA Technical Reports Server (NTRS)

    Houck, J. A.

    1983-01-01

    A simulation study assessing crew performance operating an advanced transport aircraft in an automated terminal area environment is described. The linking together of the Langley Advanced Transport Operating Systems Aft Flight Deck Simulator with the Terminal Area Air Traffic Model Simulation was required. The realism of an air traffic control (ATC) environment with audio controller instructions for the flight crews and the capability of inserting a live aircraft into the terminal area model to interact with computer generated aircraft was provided. Crew performance using the advanced displays and two separate control systems (automatic and manual) in flying area navigation routes in the automated ATC environment was assessed. Although the crews did not perform as well using the manual control system, their performances were within acceptable operational limits with little increase in workload. The crews favored using the manual control system and felt they were more alert and aware of their environment when using it.

  13. Advanced transportation system study: Manned launch vehicle concepts for two way transportation system payloads to LEO. Work breakdown structure and work breakdown structure dictionary

    NASA Technical Reports Server (NTRS)

    Duffy, James B.

    1992-01-01

    The report describes the work breakdown structure (WBS) and its associated WBS dictionary for task area 1 of contract NAS8-39207, advanced transportation system studies (ATSS). This WBS format is consistent with the preliminary design level of detail employed by both task area 1 and task area 4 in the ATSS study and is intended to provide an estimating structure for parametric cost estimates.

  14. Analyzing the Relationship of Geographic Mobility and Institutional Prestige to Career Advancement of Women in Academic Medicine Pursuing Midcareer-, Senior-, or Executive-Level Administrative Positions: Implications for Career Advancement Strategies

    ERIC Educational Resources Information Center

    McLean, Marsha Renee

    2010-01-01

    The purpose of this study was to explore the relationship of geographic mobility and institutional prestige to career advancement defined as administrative promotions of women seeking midcareer-, senior-, or executive-level positions at academic health centers (AHCs) and their medical schools or in non-AHC related medical schools in the United…

  15. Propulsion technology needs for advanced space transportation systems. [orbit maneuvering engine (space shuttle), space shuttle boosters

    NASA Technical Reports Server (NTRS)

    Gregory, J. W.

    1975-01-01

    Plans are formulated for chemical propulsion technology programs to meet the needs of advanced space transportation systems from 1980 to the year 2000. The many possible vehicle applications are reviewed and cataloged to isolate the common threads of primary propulsion technology that satisfies near term requirements in the first decade and at the same time establish the technology groundwork for various potential far term applications in the second decade. Thrust classes of primary propulsion engines that are apparent include: (1) 5,000 to 30,000 pounds thrust for upper stages and space maneuvering; and (2) large booster engines of over 250,000 pounds thrust. Major classes of propulsion systems and the important subdivisions of each class are identified. The relative importance of each class is discussed in terms of the number of potential applications, the likelihood of that application materializing, and the criticality of the technology needed. Specific technology programs are described and scheduled to fulfill the anticipated primary propulsion technology requirements.

  16. Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2018 to 2020 Period

    NASA Technical Reports Server (NTRS)

    Morgenstern, John; Norstrud, Nicole; Sokhey, Jack; Martens, Steve; Alonso, Juan J.

    2013-01-01

    Lockheed Martin Aeronautics Company (LM), working in conjunction with General Electric Global Research (GE GR), Rolls-Royce Liberty Works (RRLW), and Stanford University, herein presents results from the "N+2 Supersonic Validations" contract s initial 22 month phase, addressing the NASA solicitation "Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2018 to 2020 Period." This report version adds documentation of an additional three month low boom test task. The key technical objective of this effort was to validate integrated airframe and propulsion technologies and design methodologies. These capabilities aspired to produce a viable supersonic vehicle design with environmental and performance characteristics. Supersonic testing of both airframe and propulsion technologies (including LM3: 97-023 low boom testing and April-June nozzle acoustic testing) verified LM s supersonic low-boom design methodologies and both GE and RRLW's nozzle technologies for future implementation. The N+2 program is aligned with NASA s Supersonic Project and is focused on providing system-level solutions capable of overcoming the environmental and performance/efficiency barriers to practical supersonic flight. NASA proposed "Initial Environmental Targets and Performance Goals for Future Supersonic Civil Aircraft". The LM N+2 studies are built upon LM s prior N+3 100 passenger design studies. The LM N+2 program addresses low boom design and methodology validations with wind tunnel testing, performance and efficiency goals with system level analysis, and low noise validations with two nozzle (GE and RRLW) acoustic tests.

  17. Multi-Objective Optimization of a Turbofan for an Advanced, Single-Aisle Transport

    NASA Technical Reports Server (NTRS)

    Berton, Jeffrey J.; Guynn, Mark D.

    2012-01-01

    Considerable interest surrounds the design of the next generation of single-aisle commercial transports in the Boeing 737 and Airbus A320 class. Aircraft designers will depend on advanced, next-generation turbofan engines to power these airplanes. The focus of this study is to apply single- and multi-objective optimization algorithms to the conceptual design of ultrahigh bypass turbofan engines for this class of aircraft, using NASA s Subsonic Fixed Wing Project metrics as multidisciplinary objectives for optimization. The independent design variables investigated include three continuous variables: sea level static thrust, wing reference area, and aerodynamic design point fan pressure ratio, and four discrete variables: overall pressure ratio, fan drive system architecture (i.e., direct- or gear-driven), bypass nozzle architecture (i.e., fixed- or variable geometry), and the high- and low-pressure compressor work split. Ramp weight, fuel burn, noise, and emissions are the parameters treated as dependent objective functions. These optimized solutions provide insight to the ultrahigh bypass engine design process and provide information to NASA program management to help guide its technology development efforts.

  18. Composite transport wing technology development: Design development tests and advanced structural concepts

    NASA Technical Reports Server (NTRS)

    Griffin, Charles F.; Harvill, William E.

    1988-01-01

    Numerous design concepts, materials, and manufacturing methods were investigated for the covers and spars of a transport box wing. Cover panels and spar segments were fabricated and tested to verify the structural integrity of design concepts and fabrication techniques. Compression tests on stiffened panels demonstrated the ability of graphite/epoxy wing upper cover designs to achieve a 35 percent weight savings compared to the aluminum baseline. The impact damage tolerance of the designs and materials used for these panels limits the allowable compression strain and therefore the maximum achievable weight savings. Bending and shear tests on various spar designs verified an average weight savings of 37 percent compared to the aluminum baseline. Impact damage to spar webs did not significantly degrade structural performance. Predictions of spar web shear instability correlated well with measured performance. The structural integrity of spars manufactured by filament winding equalled or exceeded those fabricated by hand lay-up. The information obtained will be applied to the design, fabrication, and test of a full-scale section of a wing box. When completed, the tests on the technology integration box beam will demonstrate the structural integrity of an advanced composite wing design which is 25 percent lighter than the metal baseline.

  19. Study of the application of advanced technologies to laminar flow control systems for subsonic transports. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Sturgeon, R. F.; Bennett, J. A.; Etchberger, F. R.; Ferrill, R. S.; Meade, L. E.

    1976-01-01

    A study was conducted to evaluate the technical and economic feasibility of applying laminar flow control to the wings and empennage of long-range subsonic transport aircraft compatible with initial operation in 1985. For a design mission range of 10,186 km (5500 n mi), advanced technology laminar-flow-control (LFC) and turbulent-flow (TF) aircraft were developed for both 200 and 400-passenger payloads, and compared on the basis of production costs, direct operating costs, and fuel efficiency. Parametric analyses were conducted to establish the optimum geometry for LFC and TF aircraft, advanced LFC system concepts and arrangements were evaluated, and configuration variations maximizing the effectiveness of LFC were developed. For the final LFC aircraft, analyses were conducted to define maintenance costs and procedures, manufacturing costs and procedures, and operational considerations peculiar to LFC aircraft. Compared to the corresponding advanced technology TF transports, the 200- and 400-passenger LFC aircraft realized reductions in fuel consumption up to 28.2%, reductions in direct operating costs up to 8.4%, and improvements in fuel efficiency, in ssm/lb of fuel, up to 39.4%. Compared to current commercial transports at the design range, the LFC study aircraft demonstrate improvements in fuel efficiency up to 131%. Research and technology requirements requisite to the development of LFC transport aircraft were identified.

  20. A Front-Row Seat at a Wheelchair Crash Test: EP Kicks Off Its Wheelchair Transportation Safety Series with a Visit to the University of Michigan's Transportation Research Institute

    ERIC Educational Resources Information Center

    Hollingsworth, Jan Carter

    2007-01-01

    The centerpiece of the University of Michigan's Transportation Research Institute (UMTRI) Sled Lab is "the impact sled," as it is called in the business. It's the business of conducting sled impact tests, perhaps better known as crash tests, on all types of wheelchairs and wheelchair seating systems as well as wheelchair tiedowns and…

  1. 41 CFR 302-9.11 - May I receive an advance of funds for transportation and emergency storage of my POV?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of funds for transportation and emergency storage of my POV? 302-9.11 Section 302-9.11 Public... STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY STORAGE OF A PRIVATELY OWNED VEHICLE General Rules § 302-9.11 May I receive an advance of funds for transportation and emergency storage of...

  2. A Complex-Geometry Validation Experiment for Advanced Neutron Transport Codes

    SciTech Connect

    David W. Nigg; Anthony W. LaPorta; Joseph W. Nielsen; James Parry; Mark D. DeHart; Samuel E. Bays; William F. Skerjanc

    2013-11-01

    The Idaho National Laboratory (INL) has initiated a focused effort to upgrade legacy computational reactor physics software tools and protocols used for support of core fuel management and experiment management in the Advanced Test Reactor (ATR) and its companion critical facility (ATRC) at the INL.. This will be accomplished through the introduction of modern high-fidelity computational software and protocols, with appropriate new Verification and Validation (V&V) protocols, over the next 12-18 months. Stochastic and deterministic transport theory based reactor physics codes and nuclear data packages that support this effort include MCNP5[1], SCALE/KENO6[2], HELIOS[3], SCALE/NEWT[2], and ATTILA[4]. Furthermore, a capability for sensitivity analysis and uncertainty quantification based on the TSUNAMI[5] system has also been implemented. Finally, we are also evaluating the Serpent[6] and MC21[7] codes, as additional verification tools in the near term as well as for possible applications to full three-dimensional Monte Carlo based fuel management modeling in the longer term. On the experimental side, several new benchmark-quality code validation measurements based on neutron activation spectrometry have been conducted using the ATRC. Results for the first four experiments, focused on neutron spectrum measurements within the Northwest Large In-Pile Tube (NW LIPT) and in the core fuel elements surrounding the NW LIPT and the diametrically opposite Southeast IPT have been reported [8,9]. A fifth, very recent, experiment focused on detailed measurements of the element-to-element core power distribution is summarized here and examples of the use of the measured data for validation of corresponding MCNP5, HELIOS, NEWT, and Serpent computational models using modern least-square adjustment methods are provided.

  3. Potential impacts of advanced aerodynamic technology on air transportation system productivity

    NASA Technical Reports Server (NTRS)

    Bushnell, Dennis M. (Editor)

    1994-01-01

    Summaries of a workshop held at NASA Langley Research Center in 1993 to explore the application of advanced aerodynamics to airport productivity improvement are discussed. Sessions included discussions of terminal area productivity problems and advanced aerodynamic technologies for enhanced high lift and reduced noise, emissions, and wake vortex hazard with emphasis upon advanced aircraft configurations and multidisciplinary solution options.

  4. Institute for Sustainable Energy

    SciTech Connect

    Agrawal, Ajay

    2016-03-28

    Alternate fuels offer unique challenges and opportunities as energy source for power generation, vehicular transportation, and industrial applications. Institute for Sustainable Energy (ISE) at UA conducts innovative research to utilize the complex mix of domestically-produced alternate fuels to achieve low-emissions, high energy-efficiency, and fuel-flexibility. ISE also provides educational and advancement opportunities to students and researchers in the energy field. Basic research probing the physics and chemistry of alternative fuels has generated practical concepts investigated in a burner and engine test platforms.

  5. Research Study to Identify Technology Requirements for Advanced Earth-Orbital Transportation Systems, Dual-Mode Propulsion

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The results of a study of dual mode propulsion concepts applied to advanced earth orbital transportation systems using reuseable single stage to orbit vehicle concepts were summarized. Both series burn and parallel burn modes of propulsion were analyzed for vertical takeoff, horizontal landing vehicles based on accelerated technology goals. A major study objective was to assess the merits of dual mode main propulsion concepts compared to single mode concepts for carrying payloads of Space Shuttle type to orbit.

  6. Wind tunnel tests of high-lift systems for advanced transports using high-aspect-ratio supercritical wings

    NASA Technical Reports Server (NTRS)

    Allen, J. B.; Oliver, W. R.; Spacht, L. A.

    1982-01-01

    The wind tunnel testing of an advanced technology high lift system for a wide body and a narrow body transport incorporating high aspect ratio supercritical wings is described. This testing has added to the very limited low speed high Reynolds number data base for this class or aircraft. The experimental results include the effects on low speed aerodynamic characteristics of various leading and trailing edge devices, nacelles and pylons, ailerons, and spoilers, and the effects of Mach and Reynolds numbers.

  7. A two stage launch vehicle for use as an advanced space transportation system for logistics support of the space station

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This report describes the preliminary design specifications for an Advanced Space Transportation System consisting of a fully reusable flyback booster, an intermediate-orbit cargo vehicle, and a shuttle-type orbiter with an enlarged cargo bay. It provides a comprehensive overview of mission profile, aerodynamics, structural design, and cost analyses. These areas are related to the overall feasibility and usefullness of the proposed system.

  8. Safety of high speed ground transportation systems: Safety of advanced braking concepts for high speed ground transportation systems. Final report

    SciTech Connect

    Wagner, D.P.; Ahlbeck, D.R.; Luedeke, J.F.; Cook, S.D.; Dielman, M.A.

    1995-09-01

    The objective of this study is to develop qualitative and quantitative information on the various braking strategies used in high-speed ground transportation systems in support of the Federal Railroad Administration (FRA). The approach employed in this study is composed of two steps: first, build a technical understanding of the various braking strategies, and second, perform a safety analysis for each system. The systems considered in this study include seven operating high-speed rail transportation systems and three existing magnetic levitation systems. The principal technique used in the system safety analysis is Failure Modes and Effects Analysis (FMEA), an inductive approach to identifying system failure modes that depends on a thorough understanding of the system design and operation. Key elements derived from the system safety analysis are the fault-tolerant and fail-safe characteristics of the braking systems. The report concludes with recommended guidance on the structure of potential future regulations governing high-speed rail braking systems.

  9. Design of a pool boiler heat transport system for a 25 kWe advanced Stirling conversion system

    NASA Technical Reports Server (NTRS)

    Anderson, W. G.; Rosenfeld, J. H.; Noble, J.; Kesseli, J.

    1991-01-01

    The overall operating temperature and efficiency of solar-powered Stirling engines can be improved by adding a heat transport system to more uniformly supply heat to the heater head tubes. One heat transport system with favorable characteristics is an alkali metal pool boiler. An alkali metal pool boiler heat transport system was designed for a 25-kW advanced Stirling conversion system (ASCS). Solar energy concentrated on the absorber dome boils a eutectic mixture of sodium and potassium. The alkali metal vapors condense on the heater head tubes, supplying the Stirling engine with a uniform heat flux at a constant temperature. Boiling stability is achieved with the use of an enhanced boiling surface and noncondensible gas.

  10. System and Propagation Availability Analysis for NASA's Advanced Air Transportation Technologies

    NASA Technical Reports Server (NTRS)

    Ugweje, Okechukwu C.

    2000-01-01

    This report summarizes the research on the System and Propagation Availability Analysis for NASA's project on Advanced Air Transportation Technologies (AATT). The objectives of the project were to determine the communication systems requirements and architecture, and to investigate the effect of propagation on the transmission of space information. In this report, results from the first year investigation are presented and limitations are highlighted. To study the propagation links, an understanding of the total system architecture is necessary since the links form the major component of the overall architecture. This study was conducted by way of analysis, modeling and simulation on the system communication links. The overall goals was to develop an understanding of the space communication requirements relevant to the AATT project, and then analyze the links taking into consideration system availability under adverse atmospheric weather conditions. This project began with a preliminary study of the end-to-end system architecture by modeling a representative communication system in MATLAB SIMULINK. Based on the defining concepts, the possibility of computer modeling was determined. The investigations continue with the parametric studies of the communication system architecture. These studies were also carried out with SIMULINK modeling and simulation. After a series of modifications, two end-to-end communication links were identified as the most probable models for the communication architecture. Link budget calculations were then performed in MATHCAD and MATLAB for the identified communication scenarios. A remarkable outcome of this project is the development of a graphic user interface (GUI) program for the computation of the link budget parameters in real time. Using this program, one can interactively compute the link budget requirements after supplying a few necessary parameters. It provides a framework for the eventual automation of several computations

  11. TRANSPORT

    EPA Science Inventory

    Presentation outline: transport principles, effective solubility; gasoline composition; and field examples (plume diving).
    Presentation conclusions: MTBE transport follows from - phyiscal and chemical properties and hydrology. Field examples show: MTBE plumes > benzene plu...

  12. Research Advances: Less Expensive and More Convenient Gaucher's Disease Treatment; Structural Loop Regions: Key to Multidrug-Resistance Transporters?; New Method Identifies Proteins in Old Artwork

    ERIC Educational Resources Information Center

    King, Angela G.

    2006-01-01

    The X-ray structure of EmrD, a multidrug transporter protein from Escherichia coli, common bacteria known to cause several food-borne illnesses was determined by scientists at The Scripps Research Institute. The hydrophobic residues in the EmrD internal cavity are likely to contribute to the general mechanism transporting various compounds through…

  13. Capacity Building for Sustainable Seismological Networks in the Americas: A Pan-American Advanced Studies Institute on New Frontiers in Seismological Research

    NASA Astrophysics Data System (ADS)

    Cabello, O. A.; Meltzer, A.; Sandvol, E. A.; Yepes, H.; Ruiz, M. C.; Barrientos, S. E.; Willemann, R. J.

    2011-12-01

    During July 2011, a Pan-American Advanced Studies Institute, "New Frontiers in Seismological Research: Sustainable Networks, Earthquake Source Parameters, and Earth Structure" was conducted in Quito Ecuador with participants from the US, Central, and South America, and the Caribbean at early stages in their scientific careers. This advanced studies institute was imparted by fifteen volunteer senior faculty and investigators from the U.S. and the Americas. The curriculum addressed the importance of developing and maintaining modern seismological observatories, reviewed the principles of sustainable network operations, and explored recent advances in the analysis of seismological data in support of basic research, education, and hazard mitigation. An additional goal was to develop future international research collaborations. The Institute engaged graduate students, post-doctoral students, and new faculty from across the Americas in an interactive collaborative learning environment including modules on double-difference earthquake location and tomography, regional centroid-moment tensors, and event-based and ambient noise surface wave dispersion and tomography. Under the faculty guidance, participants started promising research projects about surface wave tomography in southeastern Brazil, near the Chilean triple junction, in central Chilean Andes, at the Peru-Chile border, within Peru, at a volcano in Ecuador, in the Caribbean Sea region, and near the Mendocino triple junction. Other participants started projects about moment tensors of earthquakes in or near Brazil, Chile and Argentina, Costa Rica, Ecuador, Puerto Rico, western Mexico, and northern Mexico. In order to track the progress of the participants and measure the overall effectiveness of the Institute a reunion is planned where the PASI alumni will present the result of their research that was initiated in Quito

  14. Application of advanced technologies to small, short-haul transport aircraft (STAT)

    NASA Technical Reports Server (NTRS)

    Kraus, E. F.; Mall, O. D.; Awker, R. W.; Scholl, J. W.

    1982-01-01

    The benefits of selected advanced technologies for 19 and 30 passenger, short-haul aircraft were identified. Advanced technologies were investigated in four areas: aerodynamics, propulsion, structures, and ride quality. Configuration sensitivity studies were conducted to show design tradeoffs associated with passenger capacity, cabin comfort level, and design field length.

  15. Are Summer Institutes Funded by FHWA and State Departments of Transportation Effective? Case Studies of Evaluation and Learning Strategies

    ERIC Educational Resources Information Center

    Aleong, Chandra; Aleong, John

    2008-01-01

    For the last three years Delaware State University (DSU) and the University of Vermont (UVM) have implemented a new approach to a summer program or "Institute" that emphasizes evaluation and accountability. Beginning in 2005, both institutes changed the focus of their programs to fulfill not only the primary objectives of instilling…

  16. Takeoff certification considerations for large subsonic and supersonic transport airplanes using the Ames flight simulator for advanced aircraft

    NASA Technical Reports Server (NTRS)

    Snyder, C. T.; Drinkwater, F. J., III; Fry, E. B.; Forrest, R. D.

    1973-01-01

    Data for use in development of takeoff airworthiness standards for new aircraft designs such as the supersonic transport (SST) and the large wide-body subsonic jet transport are provided. An advanced motion simulator was used to compare the performance and handling characteristics of three representative large jet transports during specific flight certification tasks. Existing regulatory constraints and methods for determining rotation speed were reviewed, and the effects on takeoff performance of variations in rotation speed, pitch attitude, and pitch attitude rate during the rotation maneuver were analyzed. A limited quantity of refused takeoff information was obtained. The aerodynamics, wing loading, and thrust-to-weight ratio of the subject SST resulted in takeoff speeds limited by climb (rather than lift-off) considerations. Take-off speeds based on U.S. subsonic transport requirements were found unacceptable because of the criticality of rotation-abuse effects on one-engine-inoperative climb performance. Adequate safety margin was provided by takeoff speeds based on proposed Anglo-French supersonic transport (TSS) criteria, with the limiting criterion being that takeoff safety speed be at least 1.15 times the one-engine-inoperative zero-rate-of-climb speed. Various observations related to SST certification are presented.

  17. Risk Methodologies for Technological Legacies : Proceedings of the NATO Advanced Study Institute, Bourgas, Bulgaria from 2 to 11 May 2000

    SciTech Connect

    Bley, Dennis C.; Droppo, James G.; Eremenko, Vitaly A.

    2003-05-01

    The Cold War Era left the major participants, the United States and the former Soviet Union (FSU), with large environmental legacies in terms of facility contamination and environmental degradation. Although the countries face similar issues from similar activities, important differences in waste management practices make the potential environmental and health risks of more immediate concern in the FSU and Eastern Europe. In the West, most nuclear and chemical waste is stored in known contained locations, while in the East much of the equivalent material is unconfined, contaminating the environment. The knowledge and experiences of the U.S. in these initial cleanup efforts are seen as important information in many North Atlantic Treaty Organization (NATO) Partner countries, where the environmental problems are more severe and the cleanup budgets more limited. An Advanced Study Institute (ASI) on ''Risk Assessment Activities for the Cold War Facilities and Environmental Legacies'' was held in Bourgas, Bulgaria, May 2-11, 2000. The objective of the ASI was to provide information to facilitate and enable decision-making activities affecting the environment and human populations in the NATO and Partner countries. Specifically, the ASI provided a forum to communicate the current status of risk analysis and management methodologies and their appropriate application. It addressed scientific approaches and application experiences from the initial U.S. risk assessment activities. This book is the product of the ASI. The power of the text lies in linking information on legacies with an integrated view of controlling the risk of those legacies. Risk can only be effectively controlled by proper balance of three central concepts: risk analysis, risk perception, and risk management. The editors were drawn together by the joint recognition that risk analysis methods had matured over the past 30 years in several fields, relatively independent of each other. It was time to

  18. Advances in Studies of Electrode Kinetics and Mass Transport in AMTEC Cells (abstract)

    NASA Technical Reports Server (NTRS)

    Williams, R. M.; Jeffries-Nakamura, B.; Ryan, M. A.; Underwood, M. L.; Kisor, A.; O'Connor, D.; Kikkert, S.

    1993-01-01

    Previous work reported from JPL has included characterization of electrode kinetics and alkali atom transport from electrodes including Mo, W, WRh(sub x), WPt(sub x)(Mn), in sodium AMTEC cells and vapor exposure cells, and Mo in potassium vapor exposure cells. These studies were generally performed in cells with small area electrodes (about 1 to 5 cm(sup 2)), and device geometry had little effect on transport. Alkali diffusion coefficients through these electrodes have been characterized, and approximate surface diffusion coefficients derived in cases of activated transport. A basic model of electrode kinetic at the alkali metal vapor/porous metal electrode/alkali beta'-alumina solid electrolyte three phase boundary has been proposed which accounts for electrochemical reaction rates with a collision frequency near the three phase boundary and tunneling from the porous electrode partially covered with adsorbed alkali metal atoms. The small electrode effect in AMTEC cells has been discussed in several papers, but quantitative investigations have described only the overall effect and the important contribution of electrolyte resistance. The quantitative characterization of transport losses in cells with large area electrodes has been limited to simulations of large area electrode effects, or characterization of transport losses from large area electrodes with significant longitudinal temperature gradients. This paper describes new investigations of electrochemical kinetics and transport, particularily with WPt(sub 3.5) electrodes, including the influence of electrode size on the mass transport loss in the AMTEC cell. These electrodes possess excellent sodium transport properties making verification of device limitations on transport much more readily attained.

  19. Study of Advanced Propulsion Systems for Small Transport Aircraft Technology (STAT) Program

    NASA Technical Reports Server (NTRS)

    Baerst, C. F.; Heldenbrand, R. W.; Rowse, J. H.

    1981-01-01

    Definitions of takeoff gross weight, performance, and direct operating cost for both a 30 and 50 passenger airplane were established. The results indicate that a potential direct operating cost benefit, resulting from advanced technologies, of approximately 20 percent would be achieved for the 1990 engines. Of the numerous design features that were evaluated, only maintenance-related items contributed to a significant decrease in direct operating cost. Recommendations are made to continue research and technology programs for advanced component and engine development.

  20. Oxygen transport membrane based advanced power cycle with low pressure synthesis gas slip stream

    DOEpatents

    Kromer, Brian R.; Litwin, Michael M.; Kelly, Sean M.

    2016-09-27

    A method and system for generating electrical power in which a high pressure synthesis gas stream generated in a gasifier is partially oxidized in an oxygen transport membrane based reactor, expanded and thereafter, is combusted in an oxygen transport membrane based boiler. A low pressure synthesis gas slip stream is split off downstream of the expanders and used as the source of fuel in the oxygen transport membrane based partial oxidation reactors to allow the oxygen transport membrane to operate at low fuel pressures with high fuel utilization. The combustion within the boiler generates heat to raise steam to in turn generate electricity by a generator coupled to a steam turbine. The resultant flue gas can be purified to produce a carbon dioxide product.

  1. ADVANCED METHODS FOR THE COMPUTATION OF PARTICLE BEAM TRANSPORT AND THE COMPUTATION OF ELECTROMAGNETIC FIELDS AND MULTIPARTICLE PHENOMENA

    SciTech Connect

    Alex J. Dragt

    2012-08-31

    Since 1980, under the grant DEFG02-96ER40949, the Department of Energy has supported the educational and research work of the University of Maryland Dynamical Systems and Accelerator Theory (DSAT) Group. The primary focus of this educational/research group has been on the computation and analysis of charged-particle beam transport using Lie algebraic methods, and on advanced methods for the computation of electromagnetic fields and multiparticle phenomena. This Final Report summarizes the accomplishments of the DSAT Group from its inception in 1980 through its end in 2011.

  2. Seeing It through: Advanced Strategies "for" Influencing Education Policy. Education Grantmakers Institute (Cambridge, Massachusetts, May 19-21, 2009)

    ERIC Educational Resources Information Center

    Mackinnon, Anne

    2009-01-01

    "No education grantmaker can afford to ignore public policy. Local, state and federal policies shape the context in which we work by establishing education standards, allocating resources and setting priorities for people working in education." So begins the report on Grantmakers for Educations' 2005 Grantmakers Institute, Foundation…

  3. The EPDA Institute for Advanced Study in Industrial Arts American Technology. Final Technical Report. (June 9 through July 18, 1969).

    ERIC Educational Resources Information Center

    Mississippi State Univ., State College.

    The major purpose of the institute was to provide industrial arts teachers with the necessary expertise to effectively interpret modern industry to their students. The program was comprised of three interrelated phases--technical information, practical application, and teaching methods and techniques. To foster an understanding of the technical…

  4. The Hispanic Association of Colleges and Universities and Hispanic-Serving Institutions: Partners in the Advancement of Hispanic Higher Education

    ERIC Educational Resources Information Center

    Calderon Galdeano, Emily; Flores, Antonio R.; Moder, John

    2012-01-01

    The relationship between the Hispanic Association of Colleges and Universities (HACU) and the recognition of Hispanic-Serving Institutions (HSIs) occurs at the federal level. HACU's origins and the legislative history of the HSI designation in federal law are explored. The demographic growth and corresponding importance of Hispanics in the…

  5. "Workplace Landscapes" and the Construction of Performance Teachers' Identity: The Case of Advanced Music Training Institutions in Greece

    ERIC Educational Resources Information Center

    Triantafyllaki, Angeliki

    2010-01-01

    This paper draws on the metaphor of "workplace landscape" to highlight the role of institutional values, evidenced within a Greek University Music Department and a Music Conservatoire, in the construction of musical performance teachers' professional identity. Underpinned by a social constructionist framework and within an ethnographic…

  6. Outcome Measurements in Higher Education. Advanced Institutional Development Program (AIDP) Two-year College Consortium, Vol. 1, No. 3.

    ERIC Educational Resources Information Center

    Harvey, L. James, Ed.

    Pressures from both outside and inside the institution are making it imperative that community colleges improve their ability to document and articulate the outputs and impacts of their programs. This document addresses itself to this issue and to the problems associated with measurement of outcomes in postsecondary education. An approach taken by…

  7. A Report of the 1969 Introductory and Advanced Institutes in Programed Instruction and Instructional Systems for Teachers of the Deaf.

    ERIC Educational Resources Information Center

    New Mexico State Univ., Las Cruces. Southwest Regional Media Center for the Deaf.

    To provide participants with intensive training in programed instruction, to make them more knowledgeable consumers of programed instruction materials, and to develop programming skills on a professional level so that they could apply the systems approach in development of instructional materials, two training institutes were initiated. A total of…

  8. Investigation of charge transport and electromagnetic effects in advanced microelectronics and optoelectronics

    SciTech Connect

    Kwan, T.; Booth, T.; Gray, M.

    1996-07-01

    This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The next generation of electronic microchips will utilize components with sub-micron feature size and optoelectronic devices with picosecond response time. Fundamental understanding of the device performance can only be obtained through first principles physics modeling of charge transport and electromagnetic effects in realistic geometries with material interfaces and dispersive properties. We have developed a general model incorporating important physics such as charge transport processes in materials with multilevel band structures and electromagnetic effects to simulate device characteristics. Accurate treatment of material interfaces and boundaries is included. The Monte Carlo charge transport is coupled self-consistently to Maxwell`s equations to accurately model scattering processes in the presence of an externally biased potential. This detailed multidimensional simulation capability is compared with and verified by experimental data, and could become an industrial standard for benchmarking and improving the {open_quotes}reduced model{close_quotes} codes used for semiconductor design. Specific tasks are the extension of existing capabilities in particle-in-cell plasma simulation technique and Monte Carlo charge transport to study the physics of charged particle dynamics in realistic microelectronic devices, such as bipolar semiconductors, heterojunction transistors, and optoelectronic switches. Our approach has been based on the coupled particle-in-cell/Monte Carlo technique, which can simultaneously treat both electromagnetic wave propagation and charged-particle transport.

  9. An Examination of Institutional Advancement Vice Presidents' Reports at Four-Year Public and Private Historically Black Colleges and Universities Regarding Their Use of the Five Minds to Promote Stewardship

    ERIC Educational Resources Information Center

    Bowen, Mya T.

    2013-01-01

    The purpose of this qualitative, collective case study was to examine institutional advancement vice presidents' reports at four-year public and private historically Black colleges and universities regarding their use of the five minds identified by Gardner's (2006) model to promote stewardship within their institutions. Gardner (2006)…

  10. A fuel conservation study for transport aircraft utilizing advanced technology and hydrogen fuel

    NASA Technical Reports Server (NTRS)

    Berry, W.; Calleson, R.; Espil, J.; Quartero, C.; Swanson, E.

    1972-01-01

    The conservation of fossil fuels in commercial aviation was investigated. Four categories of aircraft were selected for investigation: (1) conventional, medium range, low take-off gross weight; (2) conventional, long range, high take-off gross weights; (3) large take-off gross weight aircraft that might find future applications using both conventional and advanced technology; and (4) advanced technology aircraft of the future powered with liquid hydrogen fuel. It is concluded that the hydrogen fueled aircraft can perform at reduced size and gross weight the same payload/range mission as conventionally fueled aircraft.

  11. Geospatial Analysis and Optimization of Fleet Logistics to Exploit Alternative Fuels and Advanced Transportation Technologies: Preprint

    SciTech Connect

    Sparks, W.; Singer, M.

    2010-06-01

    This paper describes how the National Renewable Energy Laboratory (NREL) is developing geographical information system (GIS) tools to evaluate alternative fuel availability in relation to garage locations and to perform automated fleet-wide optimization to determine where to deploy alternative fuel and advanced technology vehicles and fueling infrastructure.

  12. Advanced system analysis for indirect methanol fuel cell power plants for transportation applications

    NASA Astrophysics Data System (ADS)

    Vanderborgh, Nicholas E.; McFarland, Robert D.; Huff, James R.

    The indirect methanol cell fuel concept actively pursued by the USDOE and General Motors Corporation proposes the development of an electrochemical engine (e.c.e.), an electrical generator capable for usually efficient and clean power production from methanol fuel for the transportation sector. This on-board generator works in consort with batteries to provide electrical power to drive propulsion motors for a range of electric vehicles. Success in this technology could do much to improve impacted environmental areas and to convert part of the transportation fleet to natural gas and coal derived methanol as the fuel source. These developments parallel work in Europe and Japan where various fuel cell powered vehicles, often fueled with tanked or hydride hydrogen, are under active development. Transportation applications present design challenges that are distinctly different from utility requirements, the thrust of most of previous fuel cell programs. In both cases, high conversion efficiency (fuel to electricity) is essential. However, transportation requirements dictate as well designs for high power densities, rapid transients including short times for system start up, and consumer safety. The e.c.e. system is formed from four interacting components: (1) the fuel processor; (2) the fuel cell stack; (3) the air compression and decompression device; and (4) the condensing cross flow heat exchange device.

  13. Study of an advanced transport airplane design concept known as Flatbed

    NASA Technical Reports Server (NTRS)

    Smethers, R. G.; Caldwell, E. W.; Warnock, W. E.; Wilson, J. M., Jr.

    1980-01-01

    The design concept and configuration of the Flatbed transport aircraft are presented. The Flatbed configuration combines into one frame, the ability to haul cargo, virtually unrestrained by cross sectional dimensions of the fuselage. The feasibility and capability of the Flatbed is discussed in depth.

  14. Predictive transport simulations of real-time profile control in JET advanced tokamak plasmas

    NASA Astrophysics Data System (ADS)

    Tala, T.; Laborde, L.; Mazon, D.; Moreau, D.; Corrigan, G.; Crisanti, F.; Garbet, X.; Heading, D.; Joffrin, E.; Litaudon, X.; Parail, V.; Salmi, A.; EFDA-JET workprogramme, contributors to the

    2005-09-01

    Predictive, time-dependent transport simulations with a semi-empirical plasma model have been used in closed-loop simulations to control the q-profile and the strength and location of the internal transport barrier (ITB). Five transport equations (Te, Ti, q, ne, vΦ) are solved, and the power levels of lower hybrid current drive, NBI and ICRH are calculated in a feedback loop determined by the feedback controller matrix. The real-time control (RTC) technique and algorithms used in the transport simulations are identical to those implemented and used in JET experiments (Laborde L. et al 2005 Plasma Phys. Control. Fusion 47 155 and Moreau D. et al 2003 Nucl. Fusion 43 870). The closed-loop simulations with RTC demonstrate that varieties of q-profiles and pressure profiles in the ITB can be achieved and controlled simultaneously. The simulations also showed that with the same RTC technique as used in JET experiments, it is possible to sustain the q-profiles and pressure profiles close to their set-point profiles for longer than the current diffusion time. In addition, the importance of being able to handle the multiple time scales to control the location and strength of the ITB is pointed out. Several future improvements and perspectives of the RTC scheme are presented.

  15. Advanced modelling of the transport phenomena across horizontal clothing microclimates with natural convection.

    PubMed

    Mayor, T S; Couto, S; Psikuta, A; Rossi, R M

    2015-12-01

    The ability of clothing to provide protection against external environments is critical for wearer's safety and thermal comfort. It is a function of several factors, such as external environmental conditions, clothing properties and activity level. These factors determine the characteristics of the different microclimates existing inside the clothing which, ultimately, have a key role in the transport processes occurring across clothing. As an effort to understand the effect of transport phenomena in clothing microclimates on the overall heat transport across clothing structures, a numerical approach was used to study the buoyancy-driven heat transfer across horizontal air layers trapped inside air impermeable clothing. The study included both the internal flow occurring inside the microclimate and the external flow occurring outside the clothing layer, in order to analyze the interdependency of these flows in the way heat is transported to/from the body. Two-dimensional simulations were conducted considering different values of microclimate thickness (8, 25 and 52 mm), external air temperature (10, 20 and 30 °C), external air velocity (0.5, 1 and 3 m s(-1)) and emissivity of the clothing inner surface (0.05 and 0.95), which implied Rayleigh numbers in the microclimate spanning 4 orders of magnitude (9 × 10(2)-3 × 10(5)). The convective heat transfer coefficients obtained along the clothing were found to strongly depend on the transport phenomena in the microclimate, in particular when natural convection is the most important transport mechanism. In such scenario, convective coefficients were found to vary in wavy-like manner, depending on the position of the flow vortices in the microclimate. These observations clearly differ from data in the literature for the case of air flow over flat-heated surfaces with constant temperature (which shows monotonic variations of the convective heat transfer coefficients, along the length of the surface). The flow

  16. Advanced modelling of the transport phenomena across horizontal clothing microclimates with natural convection

    NASA Astrophysics Data System (ADS)

    Mayor, T. S.; Couto, S.; Psikuta, A.; Rossi, R. M.

    2015-12-01

    The ability of clothing to provide protection against external environments is critical for wearer's safety and thermal comfort. It is a function of several factors, such as external environmental conditions, clothing properties and activity level. These factors determine the characteristics of the different microclimates existing inside the clothing which, ultimately, have a key role in the transport processes occurring across clothing. As an effort to understand the effect of transport phenomena in clothing microclimates on the overall heat transport across clothing structures, a numerical approach was used to study the buoyancy-driven heat transfer across horizontal air layers trapped inside air impermeable clothing. The study included both the internal flow occurring inside the microclimate and the external flow occurring outside the clothing layer, in order to analyze the interdependency of these flows in the way heat is transported to/from the body. Two-dimensional simulations were conducted considering different values of microclimate thickness (8, 25 and 52 mm), external air temperature (10, 20 and 30 °C), external air velocity (0.5, 1 and 3 m s-1) and emissivity of the clothing inner surface (0.05 and 0.95), which implied Rayleigh numbers in the microclimate spanning 4 orders of magnitude (9 × 102-3 × 105). The convective heat transfer coefficients obtained along the clothing were found to strongly depend on the transport phenomena in the microclimate, in particular when natural convection is the most important transport mechanism. In such scenario, convective coefficients were found to vary in wavy-like manner, depending on the position of the flow vortices in the microclimate. These observations clearly differ from data in the literature for the case of air flow over flat-heated surfaces with constant temperature (which shows monotonic variations of the convective heat transfer coefficients, along the length of the surface). The flow patterns and

  17. Advances in Understanding Sorption and Transport Processes Affecting the Fate of Environmental Pollutants in the Subsurface

    NASA Astrophysics Data System (ADS)

    Karapanagioti, H. K.; Werner, D.; Werth, C.

    2012-04-01

    The results of a call for a special issue that is now in press by the Journal of Contaminant Hydrology will be presented. This special issue is edited by the authors and is entitled "Sorption and Transport Processes Affecting the Fate of Environmental Pollutants in the Subsurface". A short abstract of each paper will be presented along with the most interesting results. Nine papers were accepted. Pollutants studied include: biocolloids, metals (arsenic, chromium, nickel), organic compounds such as hydrocarbons, chlorinated hydrocarbons, micropollutants (PAHs, PCBs), pesticides (glyphosate, 2,4-D). Findings presented in the papers include a modified batch reactor system to study equilibrium-reactive transport problems of metals. Column studies along with theoretical approximations evaluate the combined effects of grain size and pore water velocity on the transport in water saturated porous media of three biocolloids. A polluted sediment remediation method is evaluated considering site-specific conditions through monitoring results and modelling. A field study points to glogging and also sorption as mechanisms affecting the effectiveness of sub-surface flow constructed wetlands. A new isotherm model combining modified traditionally used isotherms is proposed that can be used to simulate pH-dependent metal adsorption. Linear free energy relationships (LFERs) demonstrate ability to predict slight isotope shifts into the groundwater due to sorption. Possible modifications that improve the reliability of kinetic models and parameter values during the evaluation of experiments that assess the sorption of pesticides on soils are tested. Challenges in selecting groundwater pollutant fate and transport models that account for the effect of grain-scale sorption rate limitations are evaluated based on experimental results and are discussed based on the Damköhler number. Finally, a thorough review paper presents the impact of mineral micropores on the transport and fate of

  18. Advanced multi-dimensional deterministic transport computational capability for safety analysis of pebble-bed reactors

    NASA Astrophysics Data System (ADS)

    Tyobeka, Bismark Mzubanzi

    A coupled neutron transport thermal-hydraulics code system with both diffusion and transport theory capabilities is presented. At the heart of the coupled code is a powerful neutronics solver, based on a neutron transport theory approach, powered by the time-dependent extension of the well known DORT code, DORT-TD. DORT-TD uses a fully implicit time integration scheme and is coupled via a general interface to the thermal-hydraulics code THERMIX-DIREKT, an HTR-specific two dimensional core thermal-hydraulics code. Feedback is accounted for by interpolating multigroup cross sections from pre-generated libraries which are structured for user specified discrete sets of thermal-hydraulic parameters e.g. fuel and moderator temperatures. The coupled code system is applied to two HTGR designs, the PBMR 400MW and the PBMR 268MW. Steady-state and several design basis transients are modeled in an effort to discern with the adequacy of using neutron diffusion theory as against the more accurate but yet computationally expensive neutron transport theory. It turns out that there are small but significant differences in the results from using either of the two theories. It is concluded that diffusion theory can be used with a higher degree of confidence in the PBMR as long as more than two energy groups are used and that the result must be checked against lower order transport solution, especially for safety analysis purposes. The end product of this thesis is a high fidelity, state-of-the-art computer code system, with multiple capabilities to analyze all PBMR safety related transients in an accurate and efficient manner.

  19. ILSI Health and Environmental Sciences Institute (HESI), global leader in advancing translational science to create science-based solutions for a sustainable, healthier world.

    PubMed

    Takei, Ayako

    2015-01-01

    The Health and Environmental Sciences Institute (HESI) is a non-profit scientific research organization based in Washington, D.C., U.S.A. HESI was established in 1989 as a global branch of the International Life Sciences Institute (ILSI) to provide an international forum to advance the understanding of scientific issues related to human health, toxicology, risk assessment and the environment. For the last 25 years, HESI has been the global leader to advance application of new science and technologies in the areas of human health, toxicology, risk assessment and environment. The core principle of "tripartite approach" and the multi-sector operational model have successfully supported HESI's scientific programs to create science-based solutions for a sustainable and healthier world. HESI's achievements include the dataset to guide the selection of appropriate supporting assays for carcinogenicity testing, a new testing framework for agricultural chemicals with enhanced efficacy, predictivity, and reduced animal usage, novel biomarkers of nephrotoxicity which provide data on the location of timing of drug effects in the kidney allowing for enhanced drug development, etc.

  20. Integrated application of active controls (IAAC) technology to an advanced subsonic transport project. Conventional baseline configuration study

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Characteristics of the U.S. domestic fleet were evaluated to determine the mission characteristics that would have the most impact on U. S. transport fuel use in the future. This resulted in selection of a 197-passenger (plus cargo), about 3710-km (2000 nmi) mission. The existing data base was reviewed and additional analysis was conducted as necessary to complete the technical descriptions. The resulting baseline configuration utilizes a double-lobe, but nearly circular, body with seven-abreast seating. External characteristics feature an 8.71 aspect ratio, 31.5-degree sweep wing, a T-tail empennage, and a dual CF6-6D2, wing-mounted engine arrangement. It provides for 22 LD-2 or 11 LD-3 containers plus bulk cargo in the lower lobe. Passenger/cargo loading, servicing provisions, taxi/takeoff speeds, and field length characteristics are all compatible with accepted airline operations and regulatory provisions. The baseline configuration construction uses conventional aluminum structure except for advanced aluminum alloys and a limited amount of graphite epoxy secondary structure. Modern systems are used, including advanced guidance, navigation, and controls which emphasize application of digital electronics and advanced displays.

  1. Advanced Transportation System Studies. Technical Area 3: Alternate Propulsion Subsystems Concepts. Volume 3; Program Cost Estimates

    NASA Technical Reports Server (NTRS)

    Levack, Daniel J. H.

    2000-01-01

    The objective of this contract was to provide definition of alternate propulsion systems for both earth-to-orbit (ETO) and in-space vehicles (upper stages and space transfer vehicles). For such propulsion systems, technical data to describe performance, weight, dimensions, etc. was provided along with programmatic information such as cost, schedule, needed facilities, etc. Advanced technology and advanced development needs were determined and provided. This volume separately presents the various program cost estimates that were generated under three tasks: the F- IA Restart Task, the J-2S Restart Task, and the SSME Upper Stage Use Task. The conclusions, technical results , and the program cost estimates are described in more detail in Volume I - Executive Summary and in individual Final Task Reports.

  2. Quantifying the "bio-" components in biophysical models of larval transport in marine benthic invertebrates: advances and pitfalls.

    PubMed

    Metaxas, Anna; Saunders, Megan

    2009-06-01

    Biophysical models are being used increasingly, both as predictive tools of larval dispersal for a particular system and for general evaluation of the role of different factors in larval transport. In the results of such models, larval duration, mortality, and behavior in the water column have exhibited pronounced effects on larval dispersal of marine benthic invertebrates. The parameterization of these processes has broadly reflected values from laboratory experiments, but the accuracy of these values is unknown. The pelagic larval duration used in models should be determined by laboratory, or preferably field, studies and should incorporate environmentally dependent variability. For mortality, in situ estimates are now feasible and, likely, more accurate than the currently used values. Larval behavior can be measured in the field, by high-frequency sampling of distributional changes relative to features in the water column or by controlled larval releases in tractable systems. To successfully validate the outcomes of these models, we must either improve our techniques for measuring larval abundance at the end of larval transport immediately before settlement, or incorporate components for settlement into the models. We must also address the mismatch in sampling resolution between biological and physical processes. If used with caution, this powerful approach can significantly advance our understanding of larval transport.

  3. Advanced transport operating system software upgrade: Flight management/flight controls software description

    NASA Technical Reports Server (NTRS)

    Clinedinst, Winston C.; Debure, Kelly R.; Dickson, Richard W.; Heaphy, William J.; Parks, Mark A.; Slominski, Christopher J.; Wolverton, David A.

    1988-01-01

    The Flight Management/Flight Controls (FM/FC) software for the Norden 2 (PDP-11/70M) computer installed on the NASA 737 aircraft is described. The software computes the navigation position estimates, guidance commands, those commands to be issued to the control surfaces to direct the aircraft in flight based on the modes selected on the Advanced Guidance Control System (AGSC) mode panel, and the flight path selected via the Navigation Control/Display Unit (NCDU).

  4. Detection of transport and age induced damages on artwork: an advanced concept

    NASA Astrophysics Data System (ADS)

    Morawitz, M.; Hein, N.; Alexeenko, I.; Wilke, M.; Pedrini, G.; Krekel, C.; Osten, W.

    2013-05-01

    For the society it is of great interest to make cultural heritage accessible to the general public. The subsequent increase of museum loan services increases the risk of accelerated degeneration. Hence, in addition to the age related deterioration, transportation can be another source of damage. Despite modern packaging technologies, vibrations and environmental climate change can add up and damage the transported object. Besides obvious mechanical influencing quantities, a main concern is the detection of climate induced damages. Changes in the relative humidity cause inner strain, which may lead to defect formations and damages. White light fringe projection was applied to detect object changes due to variations of the relative humidity. First measurements indicated a sensitivity down to a relative humidity change of 6 %. Recently, the Stuppach Madonna, a painting by Matthias Grunewald (painted 1514 - 1516), was investigated with shearography after the return from an exhibition. The obtained shearograms revealed a variety of defects like bubbles, delaminations and tunnels caused by wood worms. Even the planking of the wooden panel and existing putty could be detected. This paper describes the first steps of a project with the aim of investigating and implementing a method to detect and classify transport related damages on works of art.

  5. A single institution experience on 314 newly diagnosed advanced Hodgkin lymphoma patients: the role of ABVD in daily practice.

    PubMed

    Andjelic, Bosko; Antic, Darko; Jakovic, Ljubomir; Todorovic, Milena; Bogdanovic, Andrija; Djurasinovic, Vladislava; Bila, Jelena; Mihaljevic, Biljana

    2014-11-01

    Based on the results of clinical trials, there is no global consensus on the optimal first-line therapy for patients with advanced Hodgkin lymphoma (HL) with both ABVD and BEACOPP currently being used. However, the results of clinical trials are usually better than those in daily practice. We thus describe here our experience on 314 advanced classical HL patients treated with ABVD at the Clinical Center of Serbia and associated centers between 1997 and 2008. The median follow-up for all patients was 91 months; the estimated 5-yr event-free survival was 62% and the 5-yr overall survival (OS) 76%. Multivariate Cox regression analysis revealed that patients with IPS ≥ 3 and extranodal disease involving more than one site have a poorer outcome. The data presented here show on overall improvement in outcome as compared to more previous data and illustrate the problems of treating advanced stage HL outside the setting of a clinical trial.

  6. Oral metronomic cyclophosphamide and methotrexate plus fulvestrant in advanced breast cancer patients: a mono-institutional case-cohort report.

    PubMed

    Aurilio, Gaetano; Munzone, Elisabetta; Botteri, Edoardo; Sciandivasci, Angela; Adamoli, Laura; Minchella, Ida; Esposito, Angela; Cullurà, Daniela; Curigliano, Giuseppe; Colleoni, Marco; Goldhirsch, Aron; Nolè, Franco

    2012-09-01

    Fulvestrant is effective in postmenopausal women with estrogen receptor-positive advanced breast cancer (ABC). So far, no published data exist on fulvestrant combined with chemotherapy. We retrospectively assessed the role of combining oral metronomic cyclophosphamide and methotrexate (CM) to fulvestrant in two cohorts (A and B) of heavily pre-treated estrogen receptor-positive advanced ABC patients. From October 2006 to September 2009, 33 postmenopausal patients received fulvestrant 250 mg via i.m. injection q28 days. In A, 20 patients added metronomic cyclophosphamide (50 mg p.o. daily) and methotrexate (2.5 mg p.o. twice daily on day 1 and day 4 weekly) after disease progression, continuing fulvestrant at the same dose. In B, 13 patients started fulvestrant plus metronomic CM upfront. Thirty-two patients were evaluable for response. Clinical benefit (partial response + stable disease >24 months) for A + B was 56% (95% CI 38-74%). The addition of metronomic CM did not determine relevant toxicities. Treatment with fulvestrant plus metronomic CM was effective in advanced ABC and was minimally toxic providing long-term disease control in a high proportion of patients. The prolonged clinical benefit, often desirable in such patients, supports this regimen as an additional and useful therapeutic tool.

  7. Science of health care delivery as a first step to advance undergraduate medical education: A multi-institutional collaboration.

    PubMed

    Starr, Stephanie R; Reed, Darcy A; Essary, Alison; Hueston, William; Johnson, C Daniel; Landman, Natalie; Meurer, John; Miller, Bonnie; Ogrinc, Greg; Petty, Elizabeth M; Raymond, John; Riley, William; Gabriel, Sherine; Maurana, Cheryl

    2017-03-22

    Physicians must possess knowledge and skills to address the gaps facing the US health care system. Educators advocate for reform in undergraduate medical education (UME) to align competencies with the Triple Aim. In 2014, five medical schools and one state university began collaborating on these curricular gaps. The authors report a framework for the Science of Health Care Delivery (SHCD) using six domains and highlight curricular examples from each school. They describe three challenges and strategies for success in implementing SHCD curricula. This collaboration highlights the importance of multi-institutional partnerships to accelerate innovation and adaptation of curricula.

  8. Advances in Biomedical Imaging, Bioengineering, and Related Technologies for the Development of Biomarkers of Pancreatic Disease: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imaging and Bioengineering Workshop.

    PubMed

    Kelly, Kimberly A; Hollingsworth, Michael A; Brand, Randall E; Liu, Christina H; Singh, Vikesh K; Srivastava, Sudhir; Wasan, Ajay D; Yadav, Dhiraj; Andersen, Dana K

    2015-11-01

    A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Biomedical Imaging and Bioengineering focused on research gaps and opportunities in the development of new biomarkers of pancreatic disease. The session was held on July 22, 2015, and structured into 6 sessions: 1) Introduction and Overview; 2) Keynote Address; 3) New Approaches to the Diagnosis of Chronic Pancreatitis; 4) Biomarkers of Pain and Inflammation; 5) New Approaches to the Detection of Pancreatic Cancer; and 6) Shed Exosomes, Shed Cells, and Shed Proteins. Recent advances in the fields of pancreatic imaging, functional markers of pancreatic disease, proteomics, molecular and cellular imaging, and detection of circulating cancer cells and exosomes were reviewed. Knowledge gaps and research needs were highlighted. The development of new methods for the noninvasive determination of pancreatic pathology; the use of cellular markers of pancreatic function, inflammation, pain, and malignancy; and the refinement of methods to identify cells and cellular constituents of pancreatic cancer were discussed. The further refinement of sophisticated technical methods and the need for clinical studies to validate these new approaches in large-scale studies of patients at risk for the development of pancreatic disease were repeatedly emphasized.

  9. Advances in Biomedical Imaging, Bioengineering, and Related Technologies for the Development of Biomarkers of Pancreatic Disease: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imaging and Bioengineering Workshop

    PubMed Central

    Kelly, Kimberly A.; Hollingsworth, Michael A.; Brand, Randall E.; Liu, Christina H.; Singh, Vikesh K.; Srivastava, Sudhir; Wasan, Ajay D.; Yadav, Dhiraj; Andersen, Dana K.

    2015-01-01

    A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Biomedical Imaging and Bioengineering focused on research gaps and opportunities in the development of new biomarkers of pancreatic disease. The session was held on July 22, 2015, and structured into six sessions: 1) introduction and overview, 2) keynote address, 3) new approaches to the diagnosis of chronic pancreatitis, 4) biomarkers of pain and inflammation, 5) new approaches to the detection of pancreatic cancer, and 6) shed exosomes, shed cells, and shed proteins. Recent advances in the fields of pancreatic imaging, functional markers of pancreatic disease, proteomics, molecular and cellular imaging, and detection of circulating cancer cells and exosomes were reviewed. Knowledge gaps and research needs were highlighted. The development of new methods for the non-invasive determination of pancreatic pathology, the use of cellular markers of pancreatic function, inflammation, pain, and malignancy, and the refinement of methods to identify cells and cellular constituents of pancreatic cancer were discussed. The further refinement of sophisticated technical methods, and the need for clinical studies to validate these new approaches in large-scale studies of patients at risk for the development of pancreatic disease was repeatedly emphasized. PMID:26465948

  10. Innovative and Advanced Coupled Neutron Transport and Thermal Hydraulic Method (Tool) for the Design, Analysis and Optimization of VHTR/NGNP Prismatic Reactors

    SciTech Connect

    Rahnema, Farzad; Garimeela, Srinivas; Ougouag, Abderrafi; Zhang, Dingkang

    2013-11-29

    This project will develop a 3D, advanced coarse mesh transport method (COMET-Hex) for steady- state and transient analyses in advanced very high-temperature reactors (VHTRs). The project will lead to a coupled neutronics and thermal hydraulic (T/H) core simulation tool with fuel depletion capability. The computational tool will be developed in hexagonal geometry, based solely on transport theory without (spatial) homogenization in complicated 3D geometries. In addition to the hexagonal geometry extension, collaborators will concurrently develop three additional capabilities to increase the code’s versatility as an advanced and robust core simulator for VHTRs. First, the project team will develop and implement a depletion method within the core simulator. Second, the team will develop an elementary (proof-of-concept) 1D time-dependent transport method for efficient transient analyses. The third capability will be a thermal hydraulic method coupled to the neutronics transport module for VHTRs. Current advancements in reactor core design are pushing VHTRs toward greater core and fuel heterogeneity to pursue higher burn-ups, efficiently transmute used fuel, maximize energy production, and improve plant economics and safety. As a result, an accurate and efficient neutron transport, with capabilities to treat heterogeneous burnable poison effects, is highly desirable for predicting VHTR neutronics performance. This research project’s primary objective is to advance the state of the art for reactor analysis.

  11. Advanced Transportation System Studies. Technical Area 3: Alternate Propulsion Subsystem Concepts

    NASA Technical Reports Server (NTRS)

    Levack, Daniel J. H.

    2000-01-01

    The Alternate Propulsion Subsystem Concepts contract had seven tasks defined for this report. The tasks were: F-1A Restart Study, J-2S Restart Study, Propulsion Database Development, SSME Upper Stage Use, CERs for Liquid Propellant Rocket Engines, Advanced Low Cost Engines, and Tripropellant Comparison Study. The detailed study results, with the data to support the conclusions from various analyses, are being reported as a series of five separate Final Task Reports. Consequently, this volume only reports the required programmatic information concerning Computer Aided Design Documentation, and New Technology Reports. A detailed Executive Summary, covering all the tasks, is also available as Volume I of this report.

  12. AVID - A design system for technology studies of advanced transportation concepts. [Aerospace Vehicle Interactive Design

    NASA Technical Reports Server (NTRS)

    Wilhite, A. W.; Rehder, J. J.

    1979-01-01

    The basic AVID (Aerospace Vehicle Interactive Design) is a general system for conceptual and preliminary design currently being applied to a broad range of future space transportation and spacecraft vehicle concepts. AVID hardware includes a minicomputer allowing rapid designer interaction. AVID software includes (1) an executive program and communication data base which provide the automated capability to couple individual programs, either individually in an interactive mode or chained together in an automatic sequence mode; and (2) the individual technology and utility programs which provide analysis capability in areas such as graphics, aerodynamics, propulsion, flight performance, weights, sizing, and costs.

  13. Advanced cargo aircraft may offer a potential renaissance in freight transportation

    NASA Technical Reports Server (NTRS)

    Morris, Shelby J.; Sawyer, Wallace C.

    1993-01-01

    The increasing demand for air freight transportation has prompted studies of large, aerodynamically efficient cargo-optimized aircraft capable of carrying intermodal containers, which are typically 8 x 8 x 20 ft. Studies have accordingly been conducted within NASA to ascertain the specifications and projected operating costs of such a vehicle, as well as to identify critical, development-pacing technologies. Attention is here given not only to the rather conventional, 10-turbofan engined configuration thus arrived at, but numerous innovative configurations featuring such concepts as spanloading, removable cargo pods, and ground effect.

  14. Studies of plasma performance and transport in the advanced toroidal facility (ATF)

    SciTech Connect

    Neilson, G.H.; Bigelow, T.S.; Carreras, B.A.; Colchin, R.J.; Crume, E.C.; Dunlap, J.L.; Dyer, G.R.; England, A.C.; Glowienka, J.C.; Halliwell, J.W.; Harris, J.H.; Hedrick, C.L.; Hillis, D.L.; Hiroe, S.; Horton, L.D.; Howe, H.C.; Isler, R.C.; Jernigan, T.C.; Langley, R.A.; Lue, J.W.; Lyon, J.F.; Ma, C.H.; Mioduszewski, P.K.; Murakami, M.; Rasmussen, D.A.; Schwenterly, S.W.; Shepard, T.D.; Simpkins, J.E.; Uckan, T.; Wilgen, J.B

    1989-01-01

    An overview of recent ATF experimental results and program plans is presented, with emphasis on the role of magnetic configuration controls in transport studies. The ATF operating space is bounded by a density limit that effectively sets a limit on the energy confinement time {tau}{sub E}. Although this limit is not solely due to impurities, it has recently been raised by improved cleanliness following titanium gettering. This has led to collapse-free neutral beam injection (NBI) discharges with global {tau}{sub E} {approx} 16 ms. Preliminary experiments show that stored energy and bootstrap current are sensitive to details of the magnetic configuration. 13 refs., 8 figs.

  15. Advanced boundary condition method in quantum transport and its application in nanodevices

    NASA Astrophysics Data System (ADS)

    He, Yu

    Modern semiconductor devices have reached critical dimensions in the sub-20nm range. During the last decade, quantum transport methods have become the standard approaches to model nanoscale devices. In quantum transport methods, Schrodinger equations are solved in the critical device channel with the contacts served as the open boundary conditions. Proper and efficient treatments of these boundary conditions are essential to provide accurate prediction of device performance. The open boundary conditions, which represent charge injection and extraction effects, are described by contact self-energies. All existing contact self-energy methods assume periodic and semiinfinite contacts, which are in stark contrast to realistic devices where the contacts often have complicated geometries or imperfections. On the other hand, confined structures such as quantum dots, nanowires, and ultra-thin bodies play an important role in nanodevice designs. In the tight binding models of these confined structures, the surfaces require appropriate boundary treatments to remove the dangling bonds. The existing boundary treatments fall into two categories. One is to explicitly include the passivation atoms in the device. This is limited to passivation with atoms and small molecules due to the increasing rank of the Hamiltonian. The other is to implicitly incorporate passivation by altering the orbital energies of the dangling bonds with a passivation potential. This method only works for certain crystal structures and symmetries, and fails to distinguish different passivation scenarios, such as hydrogen and oxygen passivation. In this work, an efficient self-energy method applicable for arbitrary contact structures is developed. This method is based on an iterative algorithm which considers the explicit contact segments. The method is demonstrated on a graphene nanoribbon structure with trumpet shape contacts and a Si0.5Ge0.5 nanowire transistor with alloy disorder contacts. Furthermore

  16. Gas Research Institute advanced stimulation technology: A short course. Held in Calgary, Canada on April 28-29, 1997

    SciTech Connect

    1997-05-01

    This volume includes presentation materials prepared for a short course covering fundamental and practical information needed to understand and apply Advanced Stimulation Technology (AST). AST Deployment Program was designed to overcome barriers to the application of AST in today`s challenging economic environment. In addition to course materials, this workbook includes the short course agenda; a brief overview of AST methodology; a list of presenters with brief survey of their professional credentials and AST experience; concise information on the companies sponsoring the program; and some information on the technology transfer vehicles, i.e., information centers, publications, GRI/Net, and Regional Technology Transfer Agent program.

  17. Long term orbital storage of cryogenic propellants for advanced space transportation missions

    NASA Technical Reports Server (NTRS)

    Schuster, John R.; Brown, Norman S.

    1987-01-01

    A comprehensive study has developed the major features of a large capacity orbital propellant depot for the space-based, cryogenic OTV. The study has treated both the Dual-Keel Space Station and co-orbiting platforms as the accommodations base for the propellant storage facilities, and trades have examined both tethered and hard-docked options. Five tank set concepts were developed for storing the propellants, and along with layout options for the station and platform, were evaluated from the standpoints of servicing, propellant delivery, boiloff, micrometeoroid/debris shielding, development requirements, and cost. These trades led to the recommendation that an all-passive storage concept be considered for the platform and an actively refrigerated concept providing for reliquefaction of all boiloff be considered for the Space Station. The tank sets are modular, each storing up to 45,400 kg of LO2/LH2, and employ many advanced features to provide for microgravity fluid management and to limit boiloff. The features include such technologies as zero-gravity mass gauging, total communication capillary liquid acquisition devices, autogenous pressurization, thermodynamic vent systems, thick multilayer insulation, vapor-cooled shields, solar-selective coatings, advanced micrometeoroid/debris protection systems, and long-lived cryogenic refrigeration systems.

  18. Flight service evaluation of an advanced composite empennage component on commercial transport aircraft

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The development and flight evaluation of an advanced composite empennage component is presented. The recommended concept for the covers is graphite-epoxy hats bonded to a graphite-epoxy skin. The hat flare-out has been eliminated, instead the hat is continuous into the joint. The recommended concept for the spars is graphite-epoxy caps and a hybrid of Kevlar-49 and graphite-epoxy in the spar web. The spar cap, spar web stiffeners for attaching the ribs, and intermediate stiffeners are planned to be fabricated as a unit. Access hole in the web will be reinforced with a donut type, zero degree graphite-epoxy wound reinforcement. The miniwich design concept in the upper three ribs originally proposed is changed to a graphite-epoxy stiffened solid laminate design concept. The recommended configuration for the lower seven ribs remains as graphite-epoxy caps with aluminum cruciform diagonals. The indicated weight saving for the current advanced composite vertical fin configuration is 20.2% including a 24 lb growth allowance. The project production cost saving is approximately 1% based on a cumulative average of 250 aircraft and including only material, production labor, and quality assurance costs.

  19. Development of an advanced atmospheric/transport model for emergency response purposes

    SciTech Connect

    Fast, J.D.; O'Steen, B.L.; Addis, R.P.

    1991-07-12

    Atmospheric transport and diffusion models have been developed for real-time calculations of the location and concentration of toxic or radioactive materials during an accidental release at the Savannah River Site (SRS). These models are based Gaussian distributions and have been incorporated into an automated menu-driven program called the WIND (Weather INformation and Display) system. The WIND system atmospheric models employ certain assumptions that allow the computations of the ground-level concentration of toxic or radioactive materials to be made quickly. Gaussian models, such as PF/PL and 2DPUF, suffer from serious limitations including the inability to represent recirculation of pollutants in complex terrain, the use of one stability class at a given time to represent turbulent mixing over heterogeneous terrain, and the use of a wind field computed at only one height in the atmosphere. These limitations arise because the fundamental conservation relations of the atmosphere have been grossly simplified. Three-dimensional coupled atmospheric-dispersion models are not limited by the over-simplifications of the Gaussian assumption and have been used in the past to predict the transport of pollutants in a variety of atmospheric circulations. The disadvantage of these models is that they require large amounts of computational time; however, technology has progressed enough so that real-time simulations of dispersion may be made. These complex models can be run in an operational mode so that routine forecasts of the wind field and particulate concentration can be made.

  20. Recent Advance in the Relationship between Excitatory Amino Acid Transporters and Parkinson's Disease

    PubMed Central

    Zhang, Yunlong; Tan, Feng; Xu, Pingyi; Qu, Shaogang

    2016-01-01

    Parkinson's disease (PD) is the most common movement disorder disease in the elderly and is characterized by degeneration of dopamine neurons and formation of Lewy bodies. Glutamate is the major excitatory neurotransmitter in the central nervous system (CNS). If glutamate is not removed promptly in the synaptic cleft, it will excessively stimulate the glutamate receptors and induce excitotoxic effects on the CNS. With lack of extracellular enzyme to decompose glutamate, glutamate uptake in the synaptic cleft is mainly achieved by the excitatory amino acid transporters (EAATs, also known as high-affinity glutamate transporters). Current studies have confirmed that decreased expression and function of EAATs appear in PD animal models. Moreover, single unilateral administration of EAATs inhibitor in the substantia nigra mimics several PD features and this is a solid evidence supporting that decreased EAATs contribute to the process of PD. Drugs or treatments promoting the expression and function of EAATs are shown to attenuate dopamine neurons death in the substantia nigra and striatum, ameliorate the behavior disorder, and improve cognitive abilities in PD animal models. EAATs are potential effective drug targets in treatment of PD and thus study of relationship between EAATs and PD has predominant medical significance currently. PMID:26981287

  1. Advances in nuclear data and all-particle transport for radiation oncology

    SciTech Connect

    White, R.M.; Chadwick, M.B.; Chandler, W.P.; Hartmann Siantar, C.L.; Westbrook, C.K.

    1994-05-01

    Fast neutrons have been used to treat over 15,000 cancer patients worldwide and proton therapy is rapidly emerging as a treatment of choice for tumors around critical anatomical structures. Neutron therapy requires evaluated data to {approximately}70 MeV while proton therapy requires data to {approximately}250 MeV. Collaboration between Lawrence Livermore National Laboratory (LLNL) and the medical physics community has revealed limitations in nuclear cross section evaluations and radiation transport capabilities that have prevented neutron and proton radiation therapy centers from using Monte Carlo calculations to accurately predict dose in patients. These evaluations require energy- and angle-dependent cross sections for secondary neutrons, charged-particles and recoil nuclei. We are expanding the LLNL nuclear databases to higher energies for biologically important elements and have developed a three-dimensional, all-particle Monte Carlo radiation transport code that uses computer-assisted-tomography (CT) images as the input mesh. This code, called PEREGRINE calculates dose distributions in the human body and can be used as a tool to determine the dependence of dose on details of the evaluated nuclear data. In this paper, we will review the status of the nuclear data required for neutron and proton therapy, describe the capabilities of the PEREGRINE package, and show the effects of tissue inhomogeneities on dose distribution.

  2. Advanced Transport Delay Compensation Algorithms: Results of Delay Measurement and Piloted Performance Tests

    NASA Technical Reports Server (NTRS)

    Guo, Liwen; Cardullo, Frank M.; Kelly, Lon C.

    2007-01-01

    This report summarizes the results of delay measurement and piloted performance tests that were conducted to assess the effectiveness of the adaptive compensator and the state space compensator for alleviating the phase distortion of transport delay in the visual system in the VMS at the NASA Langley Research Center. Piloted simulation tests were conducted to assess the effectiveness of two novel compensators in comparison to the McFarland predictor and the baseline system with no compensation. Thirteen pilots with heterogeneous flight experience executed straight-in and offset approaches, at various delay configurations, on a flight simulator where different predictors were applied to compensate for transport delay. The glideslope and touchdown errors, power spectral density of the pilot control inputs, NASA Task Load Index, and Cooper-Harper rating of the handling qualities were employed for the analyses. The overall analyses show that the adaptive predictor results in slightly poorer compensation for short added delay (up to 48 ms) and better compensation for long added delay (up to 192 ms) than the McFarland compensator. The analyses also show that the state space predictor is fairly superior for short delay and significantly superior for long delay than the McFarland compensator.

  3. Development of Advanced Methods of Structural and Trajectory Analysis for Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Ardema, Mark D.; Windhorst, Robert; Phillips, James

    1998-01-01

    This paper develops a near-optimal guidance law for generating minimum fuel, time, or cost fixed-range trajectories for supersonic transport aircraft. The approach uses a choice of new state variables along with singular perturbation techniques to time-scale decouple the dynamic equations into multiple equations of single order (second order for the fast dynamics). Application of the maximum principle to each of the decoupled equations, as opposed to application to the original coupled equations, avoids the two point boundary value problem and transforms the problem from one of a functional optimization to one of multiple function optimizations. It is shown that such an approach produces well known aircraft performance results such as minimizing the Brequet factor for minimum fuel consumption and the energy climb path. Furthermore, the new state variables produce a consistent calculation of flight path angle along the trajectory, eliminating one of the deficiencies in the traditional energy state approximation. In addition, jumps in the energy climb path are smoothed out by integration of the original dynamic equations at constant load factor. Numerical results performed for a supersonic transport design show that a pushover dive followed by a pullout at nominal load factors are sufficient maneuvers to smooth the jump.

  4. Trabectedin in advanced synovial sarcomas: a multicenter retrospective study from four European institutions and the Italian Rare Cancer Network.

    PubMed

    Sanfilippo, Roberta; Dileo, Palma; Blay, Jean-Yves; Constantinidou, Anastasia; Le Cesne, Axel; Benson, Charlotte; Vizzini, Laura; Contu, Marianna; Baldi, Giacomo G; Dei Tos, Angelo P; Casali, Paolo G

    2015-07-01

    Treatment options for patients with metastatic synovial sarcoma are limited. Over recent years, trabectedin has emerged as an effective agent for patients with advanced soft tissue sarcomas resistant to anthracyclines and ifosfamide. The aim of this retrospective analysis was to study the efficacy of trabectedin in the subgroup of synovial sarcomas. A retrospective analysis was carried out on patients with advanced synovial sarcoma treated with trabectedin at four European reference sarcoma centers and within the Italian Rare Cancer Network between 2000 and 2013. Radiological response, progression-free, and overall survival, as well as serious and unexpected adverse events were retrospectively assessed. Sixty-one patients with metastatic synovial sarcoma were identified. The median number of previous chemotherapy regimens was 2 (range 1-6). Nine patients had a partial response, in addition to two minor responses, and 19 patients had stable disease, for an overall response rate of 15% and a tumor control rate of 50%. The median progression-free survival was 3 months, with 23% of patients free from progression at 6 months. The median progression-free survival in responding patients was 7 months. Trabectedin is a therapeutic option for palliative treatment of a subset of patients with metastatic synovial sarcoma.

  5. Recent advances in small molecular, non-polymeric organic hole transporting materials for solid-state DSSC

    NASA Astrophysics Data System (ADS)

    Bui, Thanh-Tuan; Goubard, Fabrice

    2013-10-01

    Issue from thin-film technologies, dye-sensitized solar cells have become one of the most promising technologies in the field of renewable energies. Their success is not only due to their low weight, the possibility of making large flexible surfaces, but also to their photovoltaic efficiency which are found to be more and more significant (>12% with a liquid electrolyte, >7% with a solid organic hole conductor). This short review highlights recent advances in the characteristics and use of low-molecular-weight glass-forming organic materials as hole transporters in all solid-state dye-sensitized solar cells. These materials must feature specific physical and chemical properties that will ensure both the operation of a photovoltaic cell and the easy implementation. This review is an english extended version based on our recent article published in Matériaux & Techniques 101, 102 (2013).

  6. Results of design studies and wind tunnel tests of an advanced high lift system for an Energy Efficient Transport

    NASA Technical Reports Server (NTRS)

    Oliver, W. R.

    1980-01-01

    The development of an advanced technology high lift system for an energy efficient transport incorporating a high aspect ratio supercritical wing is described. This development is based on the results of trade studies to select the high lift system, analysis techniques utilized to design the high lift system, and results of a wind tunnel test program. The program included the first experimental low speed, high Reynolds number wind tunnel test for this class of aircraft. The experimental results include the effects on low speed aerodynamic characteristics of various leading and trailing edge devices, nacelles and pylons, aileron, spoilers, and Mach and Reynolds numbers. Results are discussed and compared with the experimental data and the various aerodynamic characteristics are estimated.

  7. Low-speed stability and control characteristics of a transport model with aft-fuselage-mounted advanced turboprops

    NASA Technical Reports Server (NTRS)

    Applin, Z. T.; Coe, P. L., Jr.

    1986-01-01

    A limited experimental investigation was conducted in the Langley 4- by 7-Meter Tunnel to explore the effects of aft-fuselage-mounted advanced turboprop installations on the low-speed stability and control characteristics of a representative transport aircraft in a landing configuration. In general, the experimental results indicate that the longitudinal and lateral-directional stability characteristics for the aft-fuselage-mounted single-rotation tractor and counter-rotation pusher propeller configurations tested during this investigation are acceptable aerodynamically. For the single-rotation tractor configuration, the propeller-induced aerodynamics are significantly influenced by the interaction of the propeller slipstream with the pylon and nacelle. The stability characteristics for the counter-rotation pusher configuration are strongly influenced by propeller normal forces. The longitudinal and directional control effectiveness, engine-out characteristics, and ground effects are also presented. In addition, a tabulated presentation of all aerodynamic data presented in this report is included as an appendix.

  8. Heat-Pipe Development for Advanced Energy Transport Concepts Final Report Covering the Period January 1999 through September 2001

    SciTech Connect

    R.S.Reid; J.F.Sena; A.L.Martinez

    2002-10-01

    This report summarizes work in the Heat-pipe Technology Development for the Advanced Energy Transport Concepts program for the period January 1999 through September 2001. A gas-loaded molybdenum-sodium heat pipe was built to demonstrate the active pressure-control principle applied to a refractory metal heat pipe. Other work during the period included the development of processing procedures for and fabrication and testing of three types of sodium heat pipes using Haynes 230, MA 754, and MA 956 wall materials to assess the compatibility of these materials with sodium. Also during this period, tests were executed to measure the response of a sodium heat pipe to the penetration of water.

  9. Optimization of engines for a commercial Mach 0.98 transport using advanced turbine cooling methods

    NASA Technical Reports Server (NTRS)

    Kraft, G. A.; Whitlow, J. B., Jr.

    1972-01-01

    A study was made of an advanced technology airplane using supercritical aerodynamics. Cruise Mach number was 0.98 at 40,000 feet altitude with a payload of 60,000 pounds and a range of 3000 nautical miles. Separate-flow turbofans were examined parametrically to determine the effect of sea-level-static design turbine-inlet-temperature and noise on takeoff gross weight (TOGW) assuming full-film turbine cooling. The optimum turbine inlet temperature was 2650 F. Two-stage-fan engines, with cruise fan pressure ratio of 2.25, achieved a noise goal of 103.5 EPNdB with todays noise technology while one-stage-fan engines, achieved a noise goal of 98 EPNdB. The take-off gross weight penalty to use the one-stage fan was 6.2 percent.

  10. Outcomes in a Multi-institutional Cohort of Patients Treated With Intraoperative Radiation Therapy for Advanced or Recurrent Renal Cell Carcinoma

    SciTech Connect

    Paly, Jonathan J.; Hallemeier, Christopher L.; Biggs, Peter J.; Niemierko, Andrzej; Roeder, Falk; Martínez-Monge, Rafael; Whitson, Jared; Calvo, Felipe A.; Fastner, Gerd; Sedlmayer, Felix; Wong, William W.; Ellis, Rodney J.; Haddock, Michael G.; Choo, Richard; Shipley, William U.; Zietman, Anthony L.; Efstathiou, Jason A.

    2014-03-01

    Purpose/Objective(s): This study aimed to analyze outcomes in a multi-institutional cohort of patients with advanced or recurrent renal cell carcinoma (RCC) who were treated with intraoperative radiation therapy (IORT). Methods and Materials: Between 1985 and 2010, 98 patients received IORT for advanced or locally recurrent RCC at 9 institutions. The median follow-up time for surviving patients was 3.5 years. Overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) were estimated with the Kaplan-Meier method. Chained imputation accounted for missing data, and multivariate Cox hazards regression tested significance. Results: IORT was delivered during nephrectomy for advanced disease (28%) or during resection of locally recurrent RCC in the renal fossa (72%). Sixty-nine percent of the patients were male, and the median age was 58 years. At the time of primary resection, the T stages were as follows: 17% T1, 12% T2, 55% T3, and 16% T4. Eighty-seven percent of the patients had a visibly complete resection of tumor. Preoperative or postoperative external beam radiation therapy was administered to 27% and 35% of patients, respectively. The 5-year OS was 37% for advanced disease and 55% for locally recurrent disease. The respective 5-year DSS was 41% and 60%. The respective 5-year DFS was 39% and 52%. Initial nodal involvement (hazard ratio [HR] 2.9-3.6, P<.01), presence of sarcomatoid features (HR 3.7-6.9, P<.05), and higher IORT dose (HR 1.3, P<.001) were statistically significantly associated with decreased survival. Adjuvant systemic therapy was associated with decreased DSS (HR 2.4, P=.03). For locally recurrent tumors, positive margin status (HR 2.6, P=.01) was associated with decreased OS. Conclusions: We report the largest known cohort of patients with RCC managed by IORT and have identified several factors associated with survival. The outcomes for patients receiving IORT in the setting of local recurrence compare favorably to

  11. Advanced Transportation System Studies. Technical Area 3: Alternate Propulsion Subsystem Concepts. Volume 1; Executive Summary

    NASA Technical Reports Server (NTRS)

    Levack, Daniel J. H.

    2000-01-01

    The Alternate Propulsion Subsystem Concepts contract had seven tasks defined that are reported under this contract deliverable. The tasks were: FAA Restart Study, J-2S Restart Study, Propulsion Database Development. SSME Upper Stage Use. CERs for Liquid Propellant Rocket Engines. Advanced Low Cost Engines, and Tripropellant Comparison Study. The two restart studies, F-1A and J-2S, generated program plans for restarting production of each engine. Special emphasis was placed on determining changes to individual parts due to obsolete materials, changes in OSHA and environmental concerns, new processes available, and any configuration changes to the engines. The Propulsion Database Development task developed a database structure and format which is easy to use and modify while also being comprehensive in the level of detail available. The database structure included extensive engine information and allows for parametric data generation for conceptual engine concepts. The SSME Upper Stage Use task examined the changes needed or desirable to use the SSME as an upper stage engine both in a second stage and in a translunar injection stage. The CERs for Liquid Engines task developed qualitative parametric cost estimating relationships at the engine and major subassembly level for estimating development and production costs of chemical propulsion liquid rocket engines. The Advanced Low Cost Engines task examined propulsion systems for SSTO applications including engine concept definition, mission analysis. trade studies. operating point selection, turbomachinery alternatives, life cycle cost, weight definition. and point design conceptual drawings and component design. The task concentrated on bipropellant engines, but also examined tripropellant engines. The Tripropellant Comparison Study task provided an unambiguous comparison among various tripropellant implementation approaches and cycle choices, and then compared them to similarly designed bipropellant engines in the

  12. Advanced methods in global gyrokinetic full f particle simulation of tokamak transport

    SciTech Connect

    Ogando, F.; Heikkinen, J. A.; Henriksson, S.; Janhunen, S. J.; Kiviniemi, T. P.; Leerink, S.

    2006-11-30

    A new full f nonlinear gyrokinetic simulation code, named ELMFIRE, has been developed for simulating transport phenomena in tokamak plasmas. The code is based on a gyrokinetic particle-in-cell algorithm, which can consider electrons and ions jointly or separately, as well as arbitrary impurities. The implicit treatment of the ion polarization drift and the use of full f methods allow for simulations of strongly perturbed plasmas including wide orbit effects, steep gradients and rapid dynamic changes. This article presents in more detail the algorithms incorporated into ELMFIRE, as well as benchmarking comparisons to both neoclassical theory and other codes.Code ELMFIRE calculates plasma dynamics by following the evolution of a number of sample particles. Because of using an stochastic algorithm its results are influenced by statistical noise. The effect of noise on relevant magnitudes is analyzed.Turbulence spectra of FT-2 plasma has been calculated with ELMFIRE, obtaining results consistent with experimental data.

  13. Akuna - Integrated Toolsets Supporting Advanced Subsurface Flow and Transport Simulations for Environmental Management

    SciTech Connect

    Schuchardt, Karen L.; Agarwal, Deborah A.; Finsterle, Stefan A.; Gable, Carl W.; Gorton, Ian; Gosink, Luke J.; Keating, Elizabeth H.; Lansing, Carina S.; Meyer, Joerg; Moeglein, William A.M.; Pau, George S.H.; Porter, Ellen A.; Purohit, Sumit; Rockhold, Mark L.; Shoshani, Arie; Sivaramakrishnan, Chandrika

    2012-04-24

    A next generation open source subsurface simulator and user environment for environmental management is being developed through a collaborative effort across Department of Energy National Laboratories. The flow and transport simulator, Amanzi, will be capable of modeling complex subsurface environments and processes using both unstructured and adaptive meshes at very fine spatial resolutions that require supercomputing-scale resources. The user environment, Akuna, provides users with a range of tools to manage environmental and simulator data sets, create models, manage and share simulation data, and visualize results. Underlying the user interface are core toolsets that provide algorithms for sensitivity analysis, parameter estimation, and uncertainty quantification. Akuna is open-source, cross platform software that is initially being demonstrated on the Hanford BC Cribs remediation site. In this paper, we describe the emerging capabilities of Akuna and illustrate how these are being applied to the BC Cribs site.

  14. Design philosophy of long range LFC transports with advanced supercritical LFC airfoils. [laminar flow control

    NASA Technical Reports Server (NTRS)

    Pfenninger, Werner; Vemuru, Chandra S.

    1988-01-01

    The achievement of 70 percent laminar flow using modest boundary layer suction on the wings, empennage, nacelles, and struts of long-range LFC transports, combined with larger wing spans and lower span loadings, could make possible an unrefuelled range halfway around the world up to near sonic cruise speeds with large payloads. It is shown that supercritical LFC airfoils with undercut front and rear lower surfaces, an upper surface static pressure coefficient distribution with an extensive low supersonic flat rooftop, a far upstream supersonic pressure minimum, and a steep subsonic rear pressure rise with suction or a slotted cruise flap could alleviate sweep-induced crossflow and attachment-line boundary-layer instability. Wing-mounted superfans can reduce fuel consumption and engine tone noise.

  15. Technology and Engineering Advances Supporting EarthScope's Alaska Transportable Array

    NASA Astrophysics Data System (ADS)

    Miner, J.; Enders, M.; Busby, R.

    2015-12-01

    EarthScope's Transportable Array (TA) in Alaska and Canada is an ongoing deployment of 261 high quality broadband seismographs. The Alaska TA is the continuation of the rolling TA/USArray deployment of 400 broadband seismographs in the lower 48 contiguous states and builds on the success of the TA project there. The TA in Alaska and Canada is operated by the IRIS Consortium on behalf of the National Science Foundation as part of the EarthScope program. By Sept 2015, it is anticipated that the TA network in Alaska and Canada will be operating 105 stations. During the summer of 2015, TA field crews comprised of IRIS and HTSI station specialists, as well as representatives from our partner agencies the Alaska Earthquake Center and the Alaska Volcano Observatory and engineers from the UNAVCO Plate Boundary Observatory will have completed a total of 36 new station installations. Additionally, we will have completed upgrades at 9 existing Alaska Earthquake Center stations with borehole seismometers and the adoption of an additional 35 existing stations. Continued development of battery systems using LiFePO4 chemistries, integration of BGAN, Iridium, Cellular and VSAT technologies for real time data transfer, and modifications to electronic systems are a driving force for year two of the Alaska Transportable Array. Station deployment utilizes custom heliportable drills for sensor emplacement in remote regions. The autonomous station design evolution include hardening the sites for Arctic, sub-Arctic and Alpine conditions as well as the integration of rechargeable Lithium Iron Phosphate batteries with traditional AGM batteries We will present new design aspects, outcomes, and lessons learned from past and ongoing deployments, as well as efforts to integrate TA stations with other existing networks in Alaska including the Plate Boundary Observatory and the Alaska Volcano Observatory.

  16. Outcome prediction of advanced mantle cell lymphoma by international prognostic index versus different mantle cell lymphoma indexes: one institution study.

    PubMed

    Todorovic, Milena; Balint, Bela; Andjelic, Bosko; Stanisavljevic, Dejana; Kurtovic, Nada Kraguljac; Radisavljevic, Ziv; Mihaljevic, Biljana

    2012-09-01

    The aim of this study was to evaluate the prognostic significance of international prognostic index (IPI), mantle cell lymphoma IPI (MIPI), simplified MIPI (sMIPI), and MIPI biological (MIPIb), as well as their correlation with immunophenotype, clinical characteristics, and overall survival (OS), in a selected group of 54 patients with advanced-stage mantle cell lymphoma (MCL), treated uniformly with CHOP. Seventeen patients had IV clinical stage (CS), while other 37 had leukemic phase at presentation. Diffuse type of marrow infiltration was verified in 68.5% and nodular in remainder patients. Extranodal localization (25.9%) included bowel (20.4%), pleural effusion, sinus, and palpebral infiltration. All of analyzed patients expressed typical MCL immunophenotypic profile: CD19(+)CD20(+)CD22(+)CD5(+)Cyclin-D1(+)FMC7(+)CD79b(+)smIg(+)CD38(+/-)CD23(-)CD10(-). Median OS of the whole group was 23 months, without significant differences between IV CS and leukemic phase patients. Thirty-two patients (59.3%) responded to initial treatment, 9 (16.7%) with complete and 23 (42.6%) with partial remission. Negative prognostic influence on OS had high IPI (P < 0.01), high sMIPI (P < 0.001), MIPI (P < 0.01), MIPIb (P < 0.01), extranodal localization (P < 0.01), and diffuse marrow infiltration (P < 0.01). Testing between randomly selected groups showed that patients with lower proportion of CD5(+) cells (<80%) correlated with cytological blastoid variant and had shorter survival comparing with the group with higher proportion of CD5(+) cells (>80%) (P < 0.01). Using univariate Cox regression, we proved that IPI, sMIPI, MIPI, and MIPIb had an independent predictive importance (P < 0.01) for OS in uniformly treated advanced MCL patients, although sMIPI prognostic significance was the highest (P < 0.001).

  17. Improvements in Thermal Protection Sizing Capabilities for TCAT: Conceptual Design for Advanced Space Transportation Systems

    NASA Technical Reports Server (NTRS)

    Olds, John R.; Izon, Stephen James

    2002-01-01

    The Thermal Calculation Analysis Tool (TCAT), originally developed for the Space Systems Design Lab at the Georgia Institute of Technology, is a conceptual design tool capable of integrating aeroheating analysis into conceptual reusable launch vehicle design. It provides Thermal Protection System (TPS) unit thicknesses and acreage percentages based on the geometry of the vehicle and a reference trajectory to be used in calculation of the total cost and weight of the vehicle design. TCAT has proven to be reasonably accurate at calculating the TPS unit weights for in-flight trajectories; however, it does not have the capability of sizing TPS materials above cryogenic fuel tanks for ground hold operations. During ground hold operations, the vehicle is held for a brief period (generally about two hours) during which heat transfer from the TPS materials to the cryogenic fuel occurs. If too much heat is extracted from the TPS material, the surface temperature may fall below the freezing point of water, thereby freezing any condensation that may be present at the surface of the TPS. Condensation or ice on the surface of the vehicle is potentially hazardous to the mission and can also damage the TPS. It is questionable whether or not the TPS thicknesses provided by the aeroheating analysis would be sufficiently thick to insulate the surface of the TPS from the heat transfer to the fuel. Therefore, a design tool has been developed that is capable of sizing TPS materials at these cryogenic fuel tank locations to augment TCAT's TPS sizing capabilities.

  18. Advanced Transportation System Studies Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development Contract. Volume 2; Technical Results

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The purpose of the Advanced Transportation System Studies (ATSS) Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is Volume 2 of the final report for the contract. It provides documentation of selected technical results from various TA-2 analysis activities, including a detailed narrative description of the SSTO concept assessment results, a user's guide for the associated SSTO sizing tools, an SSTO turnaround assessment report, an executive summary of the ground operations assessments performed during the first year of the contract, a configuration-independent vehicle health management system requirements report, a copy of all major TA-2 contract presentations, a copy of the FLO launch vehicle final report, and references to Pratt & Whitney's TA-2 sponsored final reports regarding the identification of Russian main propulsion technologies.

  19. The use of regional advance mitigation planning (RAMP) to integrate transportation infrastructure impacts with sustainability; a perspective from the USA

    NASA Astrophysics Data System (ADS)

    Thorne, James H.; Huber, Patrick R.; O'Donoghue, Elizabeth; Santos, Maria J.

    2014-05-01

    Globally, urban areas are expanding, and their regional, spatially cumulative, environmental impacts from transportation projects are not typically assessed. However, incorporation of a Regional Advance Mitigation Planning (RAMP) framework can promote more effective, ecologically sound, and less expensive environmental mitigation. As a demonstration of the first phase of the RAMP framework, we assessed environmental impacts from 181 planned transportation projects in the 19 368 km2 San Francisco Bay Area. We found that 107 road and railroad projects will impact 2411-3490 ha of habitat supporting 30-43 threatened or endangered species. In addition, 1175 ha of impacts to agriculture and native vegetation are expected, as well as 125 crossings of waterways supporting anadromous fish species. The extent of these spatially cumulative impacts shows the need for a regional approach to associated environmental offsets. Many of the impacts were comprised of numerous small projects, where project-by-project mitigation would result in increased transaction costs, land costs, and lost project time. Ecological gains can be made if a regional approach is taken through the avoidance of small-sized reserves and the ability to target parcels for acquisition that fit within conservation planning designs. The methods are straightforward, and can be used in other metropolitan areas.

  20. 41 CFR 302-9.11 - May I receive an advance of funds for transportation and emergency storage of my POV?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of funds for transportation and emergency storage of my POV? 302-9.11 Section 302-9.11 Public... General Rules § 302-9.11 May I receive an advance of funds for transportation and emergency storage of my... storage of your POV. Effective Date Note: By FTR Amdt. 2011-01, 76 FR 18342, Apr. 1, 2011, § 302-9.11...

  1. Benefits associated with advanced technologies applied to a high-speed civil transport concept

    NASA Technical Reports Server (NTRS)

    Ozoroski, L. P.; Shields, E. W.; Fenbert, J. W.; Mcelroy, M. O.

    1993-01-01

    Results of a first-order assessment of the mission performance benefits associated with the technology improvements and goals of the Phase II High-Speed Research (HSR) Program are presented. A breakdown of the four major disciplines resulted in the following estimated TOGW savings from the 1990 vehicle: propulsion at 14.3 percent, structures at 11.7 percent, flight-deck systems at 4.0 percent, and aerodynamics at 15.0 percent. Based on 100 percent success of the HSR Phase II proposed technology advancements, the overall combined impact is estimated to result in a 45 percent reduction in TOGW from a 1990 entry-into-service (EIS) date, which could result in a viable 2005 EIS vehicle with an acceptable TOGW that meets Stage III community noise restrictions. Through supersonic laminar flow control and the possible reduction in reserve fuel requirements resulting from synthetic vision capability, the potential exists for an additional 9.6 percent reduction in TOGW.

  2. The FM-007: An advanced jet commuter for HUB to spoke transportation

    NASA Technical Reports Server (NTRS)

    Blouke, Peter Scott; Engel, George Bryan; Fordham, Kari Suzanne; Layne, Steven James; Moore, Joel David; Shaver, Frederick Martin; Thornton, Douglas Hershal, Jr.

    1991-01-01

    Due to the increasing need for new commuter aircraft, the FM-007 is proposed, a technologically advanced jet propelled short takeoff and landing (STOL) airplane. The proposed commuter is designed for hub to spoke air travel. In order to reduce drag, natural laminar flow technology is integrated into the design using the natural laminar flow airfoil section for the wing. A three lifting surface configuration provides for more efficient cruise flight. This unique design includes a small forward wing (canard), a rear mounted high aspect ratio main wing, and a small horizontal stabilizer high atop the vertical tail. These three surfaces act together to reduce drag by minimizing the downward force the horizontal stabilizer has to account for due to the nose down pitching moment. Commuter aircraft must also incorporate passenger comfort. This is achieved by providing a spacious pressurized cabin with a large galley and reduced cabin noise due to incorporation of noise reduction gear. A basic oval design is adopted, as opposed to a circular design in order to allow for the seating of five passengers abreast. To get STOL capability, an over the wing blown flap is used using a Rolls Royce Tay series engine.

  3. Advanced Technology Vehicle Program of the Maryland Department of Transportation and Metropolitan Washington Council of Governments

    SciTech Connect

    Freudberg, Stuart A.

    2001-03-31

    A multi-year Clean Alternative program is designed to integrate low-emission advanced technology vehicles into high mileage/high-fuel-use public and private fleets, which are major contributors to high pollution levels. The primary goal of the program is reduced emissions of nitrogen oxides (NO{sub x}) from on-road vehicles in the Maryland counties surrounding Washington, DC. The program is targeted at fleets operating in Calvert, Charles, Frederick, Montgomery and Prince George's counties. Eligible types of vehicle applications include taxicabs, shuttles, buses, and delivery vans and trucks. Other types may qualify if they meet certain annual fuel-use or mileage criteria. Minimum requirements have been established for participating companies, including size of fleet and age of firm. The first vehicles under this program were placed in service in 1999. The Clean Alternative provides financial incentives to selected qualified firms that purchase original equipment manufacturer (OEM) vehicles or heavy-duty engines that have been certified to Low Emission Vehicle (LEV) emission levels or lower. This program is intended to be flexible and to evolve over time. For instance, in coming years the standards for acceptable emission levels may be tightened. The level of financial incentive will be determined on a case-by-case basis and other types of incentives may be provided in some cases. The range of counties included may be extended in the future or criteria for participation changed to help meet the air quality goals of the region.

  4. Pool boiler heat transport system for a 25 kWe advanced Stirling conversion system

    NASA Technical Reports Server (NTRS)

    Anderson, W. G.; Rosenfeld, J. H.; Saaski, E. L.; Noble, J.; Tower, L.

    1990-01-01

    Experiments to determine alkali metal/enhanced surface combinations that have stable boiling at the temperatures and heat fluxes that occur in the Stirling engine are reported. Two enhanced surfaces and two alkali metal working fluids were evaluated. The enhanced surfaces were an EDM hole covered surface and a sintered-powder-metal porous layer surface. The working fluids tested were potassium and eutectic sodium-potasium alloy (NaK), both with and without undissolved noncondensible gas. Noncondensible gas (He and Xe) was added to the system to provide gas in the nucleation sites, preventing quenching of the sites. The experiments demonstrated the potential of an alkali metal pool boiler heat transport system for use in a solar-powered Stirling engine. The most favorable fluid/surface combination tested was NaK boiling on a -100 +140 mesh 304L stainless steel sintered porous layer with no undissolved noncondensible gas. This combination provided stable, high-performance boiling at the operating temperature of 700 C. Heat fluxes into the system ranged from 10 to 50 W/sq cm. The transition from free convection to nucleate boiling occurred at temperatures near 540 C. Based on these experiments, a pool boiler was designed for a full-scale 25-kWe Stirling system.

  5. Improvement of Advanced Parkinson's Disease Manifestations with Deep Brain Stimulation of the Subthalamic Nucleus: A Single Institution Experience.

    PubMed

    Rabie, Ahmed; Verhagen Metman, Leo; Fakhry, Mazen; Eassa, Ayman Youssef Ezeldin; Fouad, Wael; Shakal, Ahmed; Slavin, Konstantin V

    2016-12-13

    We present our experience at the University of Illinois at Chicago (UIC) in deep brain stimulation (DBS) of the subthalamic nucleus (STN), describing our surgical technique, and reporting our clinical results, and morbidities. Twenty patients with advanced Parkinson's disease (PD) who underwent bilateral STN-DBS were studied. Patients were assessed preoperatively and followed up for one year using the Unified Parkinson's Disease Rating Scale (UPDRS) in "on" and "off" medication and "on" and "off" stimulation conditions. At one-year follow-up, we calculated significant improvement in all the motor aspects of PD (UPDRS III) and in activities of daily living (UPDRS II) in the "off" medication state. The "off" medication UPDRS improved by 49.3%, tremors improved by 81.6%, rigidity improved by 50.0%, and bradykinesia improved by 39.3%. The "off" medication UPDRS II scores improved by 73.8%. The Levodopa equivalent daily dose was reduced by 54.1%. The UPDRS IVa score (dyskinesia) was reduced by 65.1%. The UPDRS IVb score (motor fluctuation) was reduced by 48.6%. Deep brain stimulation of the STN improves the cardinal motor manifestations of the idiopathic PD. It also improves activities of daily living, and reduces medication-induced complications.

  6. Improvement of Advanced Parkinson’s Disease Manifestations with Deep Brain Stimulation of the Subthalamic Nucleus: A Single Institution Experience

    PubMed Central

    Rabie, Ahmed; Verhagen Metman, Leo; Fakhry, Mazen; Eassa, Ayman Youssef Ezeldin; Fouad, Wael; Shakal, Ahmed; Slavin, Konstantin V.

    2016-01-01

    We present our experience at the University of Illinois at Chicago (UIC) in deep brain stimulation (DBS) of the subthalamic nucleus (STN), describing our surgical technique, and reporting our clinical results, and morbidities. Twenty patients with advanced Parkinson’s disease (PD) who underwent bilateral STN-DBS were studied. Patients were assessed preoperatively and followed up for one year using the Unified Parkinson’s Disease Rating Scale (UPDRS) in “on” and “off” medication and “on” and “off” stimulation conditions. At one-year follow-up, we calculated significant improvement in all the motor aspects of PD (UPDRS III) and in activities of daily living (UPDRS II) in the “off” medication state. The “off” medication UPDRS improved by 49.3%, tremors improved by 81.6%, rigidity improved by 50.0%, and bradykinesia improved by 39.3%. The “off” medication UPDRS II scores improved by 73.8%. The Levodopa equivalent daily dose was reduced by 54.1%. The UPDRS IVa score (dyskinesia) was reduced by 65.1%. The UPDRS IVb score (motor fluctuation) was reduced by 48.6%. Deep brain stimulation of the STN improves the cardinal motor manifestations of the idiopathic PD. It also improves activities of daily living, and reduces medication-induced complications. PMID:27983589

  7. Accelerating Scientific Advancement for Pediatric Rare Lung Disease Research. Report from a National Institutes of Health-NHLBI Workshop, September 3 and 4, 2015.

    PubMed

    Young, Lisa R; Trapnell, Bruce C; Mandl, Kenneth D; Swarr, Daniel T; Wambach, Jennifer A; Blaisdell, Carol J

    2016-12-01

    Pediatric rare lung disease (PRLD) is a term that refers to a heterogeneous group of rare disorders in children. In recent years, this field has experienced significant progress marked by scientific discoveries, multicenter and interdisciplinary collaborations, and efforts of patient advocates. Although genetic mechanisms underlie many PRLDs, pathogenesis remains uncertain for many of these disorders. Furthermore, epidemiology and natural history are insufficiently defined, and therapies are limited. To develop strategies to accelerate scientific advancement for PRLD research, the NHLBI of the National Institutes of Health convened a strategic planning workshop on September 3 and 4, 2015. The workshop brought together a group of scientific experts, intramural and extramural investigators, and advocacy groups with the following objectives: (1) to discuss the current state of PRLD research; (2) to identify scientific gaps and barriers to increasing research and improving outcomes for PRLDs; (3) to identify technologies, tools, and reagents that could be leveraged to accelerate advancement of research in this field; and (4) to develop priorities for research aimed at improving patient outcomes and quality of life. This report summarizes the workshop discussion and provides specific recommendations to guide future research in PRLD.

  8. a History of Funding for WOMEN’S Programs at the National Science Foundation: from Individual Powre Approaches to the Advance of Institutional Approaches

    NASA Astrophysics Data System (ADS)

    Rosser, Sue V.; Lane, Eliesh O'neil

    The biennial reports on women, minorities, and persons with disabilities produced by the National Science Foundation (NSF) because of congressional mandate laid the statistical foundation for NSF initiatives to redress the underrepresentation of these groups. Programs established in the 1980s such as Research Opportunities for Women, Visiting Professorships for Women, Graduate Fellowships for Women, and Career Advancement Awards provided support to individual women for their research. In the 1990s, the NSF also began to focus on systemic initiatives, creating the Program for Women and Girls, although it continued to address the problem through support of individual researchers in the newly created Professional Opportunities for Women in Research and Education (POWRE) initiative. The responses from more than 400 awardees during the 4 years of POWRE provide insights into the current issues these women perceive surrounding their grants, funding, and interactions with NSF bureaucracy and staff members. The results of the POWRE survey support the institutional, systemic thrust of the NSF’s new ADVANCE initiative to attempt to solve problems such as balancing career and family that cannot be addressed solely by supporting research projects of individual female scientists and engineers.

  9. Mechanical design engineering. NASA/university advanced design program: Lunar Bulk Material Transport Vehicle

    NASA Technical Reports Server (NTRS)

    Daugherty, Paul; Griner, Stewart; Hendrix, Alan; Makarov, Chris; Martiny, Stephen; Meyhoefer, Douglas Ralph; Platt, Cody Claxton; Sivak, John; Wheeler, Elizabeth Fitch

    1988-01-01

    The design of a Lunar Bulk Material Transport Vehicle (LBMTV) is discussed. Goals set in the project include a payload of 50 cubic feet of lunar soil with a lunar of approximately 800 moon-pounds, a speed of 15 mph, and the ability to handle a grade of 20 percent. Thermal control, an articulated steering mechanism, a dump mechanism, a self-righting mechanism, viable power sources, and a probable control panel are analyzed. The thermal control system involves the use of small strip heaters to heat the housing of electronic equipment in the absence of sufficient solar radiation and multi-layer insulation during periods of intense solar radiation. The entire system uses only 10 W and weighs about 60 pounds, or 10 moon-pounds. The steering mechanism is an articulated steering joint at the center of the vehicle. It utilizes two actuators and yields a turning radius of 10.3 feet. The dump mechanism rotates the bulk material container through an angle of 100 degree using one actuator. The self-righting mechanism consists of two four bar linkages, each of which is powered by the same size actuator as the other linkages. The LBMTV is powered by rechargeable batteries. A running time of at least two hours is attained under a worst case analysis. The weight of the batteries is 100 pounds. A control panel consisting of feedback and control instruments is described. The panel includes all critical information necessary to control the vehicle remotely. The LBMTV is capable of handling many types of cargo. It is able to interface with many types of removable bulk material containers. These containers are made to interface with the three-legged walker, SKITTER. The overall vehicle is about 15 feet in length and has a weight of about 1000 pounds, or 170 lunar pounds.

  10. Mechanical design engineering. NASA/university advanced design program: Lunar Bulk Material Transport Vehicle

    NASA Astrophysics Data System (ADS)

    Daugherty, Paul; Griner, Stewart; Hendrix, Alan; Makarov, Chris; Martiny, Stephen; Meyhoefer, Douglas Ralph; Platt, Cody Claxton; Sivak, John; Wheeler, Elizabeth Fitch

    1988-06-01

    The design of a Lunar Bulk Material Transport Vehicle (LBMTV) is discussed. Goals set in the project include a payload of 50 cubic feet of lunar soil with a lunar of approximately 800 moon-pounds, a speed of 15 mph, and the ability to handle a grade of 20 percent. Thermal control, an articulated steering mechanism, a dump mechanism, a self-righting mechanism, viable power sources, and a probable control panel are analyzed. The thermal control system involves the use of small strip heaters to heat the housing of electronic equipment in the absence of sufficient solar radiation and multi-layer insulation during periods of intense solar radiation. The entire system uses only 10 W and weighs about 60 pounds, or 10 moon-pounds. The steering mechanism is an articulated steering joint at the center of the vehicle. It utilizes two actuators and yields a turning radius of 10.3 feet. The dump mechanism rotates the bulk material container through an angle of 100 degree using one actuator. The self-righting mechanism consists of two four bar linkages, each of which is powered by the same size actuator as the other linkages. The LBMTV is powered by rechargeable batteries. A running time of at least two hours is attained under a worst case analysis. The weight of the batteries is 100 pounds. A control panel consisting of feedback and control instruments is described. The panel includes all critical information necessary to control the vehicle remotely. The LBMTV is capable of handling many types of cargo. It is able to interface with many types of removable bulk material containers. These containers are made to interface with the three-legged walker, SKITTER. The overall vehicle is about 15 feet in length and has a weight of about 1000 pounds, or 170 lunar pounds.

  11. Correlation between vitiligo occurrence and clinical benefit in advanced melanoma patients treated with nivolumab: A multi-institutional retrospective study.

    PubMed

    Nakamura, Yasuhiro; Tanaka, Ryota; Asami, Yuri; Teramoto, Yukiko; Imamura, Taichi; Sato, Sayuri; Maruyama, Hiroshi; Fujisawa, Yasuhiro; Matsuya, Taisuke; Fujimoto, Manabu; Yamamoto, Akifumi

    2016-08-11

    Vitiligo is occasionally seen in melanoma patients. Although several studies indicate a correlation between vitiligo occurrence and clinical response in melanoma patients receiving immunotherapy, most studies have included heterogeneous patient and treatment settings. The aim of this study is to investigate the correlation between the occurrence of vitiligo and clinical benefit of nivolumab treatment in advanced melanoma patients. We retrospectively reviewed unresectable stage III or IV melanoma patients treated with nivolumab. Of 35 melanoma patients treated with nivolumab, 25.7% (9/35) developed vitiligo during treatment. The time from the start of nivolumab treatment to occurrence of vitiligo ranged 2-9 months (mean, 5.2). Of nine patients who developed vitiligo, two (22.2%) had a complete response to nivolumab and two (22.2%) had a partial response. The objective response rate was significantly higher in patients with vitiligo than in patients without vitiligo (4/9 [44.4%] vs 2/26 [7.7%]; P = 0.027). The mean time to vitiligo occurrence in patients achieving an objective response was significantly less than that in patients who showed no response (3.1 vs 6.8 months, P = 0.004). Vitiligo occurrence was significantly associated with prolonged progression-free and overall survival (hazard ratio, 0.24 and 0.16; 95% confidence interval, 0.11-0.55 and 0.03-0.79; P = 0.005, and 0.047, respectively). At the 20-week landmark analysis, however, vitiligo was not associated with a statistically significant overall survival benefit (P = 0.28). The occurrence of vitiligo during nivolumab treatment may be correlated with favorable clinical outcome.

  12. 76 FR 62149 - American Chemistry Council, The Chlorine Institute, Inc., the Fertilizer Institute, and PPG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board American Chemistry Council, The Chlorine Institute, Inc., the Fertilizer... American Chemistry Council, The Chlorine Institute, Inc., The Fertilizer Institute (TFI), and...

  13. Advanced Technology Subsonic Transport Study: N+3 Technologies and Design Concepts

    NASA Technical Reports Server (NTRS)

    Raymer, Daniel P.; Wilson, Jack; Perkins, H. Douglas; Rizzi, Arthur; Zhang, Mengmeng; RamirezPuentes, Alfredo

    2011-01-01

    Conceptual Research Corporation, the Science of the Possible, has completed a two-year study of concepts and technologies for future airliners in the 180-passenger class. This NASA-funded contract was primarily focused on the ambitious goal of a 70 percent reduction in fuel consumption versus the market-dominating Boeing 737-800. The study is related to the N+3 contracts awarded in 2008 by NASA s Aeronautics Research Mission Directorate to teams led by Boeing, GE Aviation, MIT, and Northrop Grumman, but with more modest goals and funding. CRC s contract featured a predominant emphasis on propulsion and fuel consumption, but since fuel consumption depends upon air vehicle design as much as on propulsion technology, the study included notional vehicle design, analysis, and parametric studies. Other NASA goals including NOx and noise reduction are of long-standing interest but were not highlighted in this study, other than their inclusion in the propulsion system provided to CRC by NASA. The B-737-800 was used as a benchmark, parametric tool, and design point of departure. It was modeled in the RDS-Professional aircraft design software then subjected to extensive parametric variations of parasitic drag, drag-due-to-lift, specific fuel consumption, and unsized empty weight. These studies indicated that the goal of a 70 percent reduction in fuel consumption could be attained with roughly a 30 percent improvement in all four parameters. The results were then fit to a Response Surface and coded for ease of use in subsequent trade studies. Potential technologies to obtain such savings were identified and discussed. More than 16 advanced concept designs were then prepared, attempting to investigate almost every possible emerging concept for application to this class airliner. A preliminary assessment of these concepts was done based on their total wetted area after design normalization of trimmed maximum lift. This assessment points towards a Tailless Airliner concept which

  14. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project. ACT/Control/Guidance System study. Volume 2: Appendices

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The integrated application of active controls (IAAC) technology to an advanced subsonic transport is reported. Supplementary technical data on the following topics are included: (1) 1990's avionics technology assessment; (2) function criticality assessment; (3) flight deck system for total control and functional features list; (4) criticality and reliability assessment of units; (5) crew procedural function task analysis; and (6) recommendations for simulation mechanization.

  15. Toward a Mechanistic Source Term in Advanced Reactors: Characterization of Radionuclide Transport and Retention in a Sodium Cooled Fast Reactor

    SciTech Connect

    Brunett, Acacia J.; Bucknor, Matthew; Grabaskas, David

    2016-04-17

    A vital component of the U.S. reactor licensing process is an integrated safety analysis in which a source term representing the release of radionuclides during normal operation and accident sequences is analyzed. Historically, source term analyses have utilized bounding, deterministic assumptions regarding radionuclide release. However, advancements in technical capabilities and the knowledge state have enabled the development of more realistic and best-estimate retention and release models such that a mechanistic source term assessment can be expected to be a required component of future licensing of advanced reactors. Recently, as part of a Regulatory Technology Development Plan effort for sodium cooled fast reactors (SFRs), Argonne National Laboratory has investigated the current state of knowledge of potential source terms in an SFR via an extensive review of previous domestic experiments, accidents, and operation. As part of this work, the significant sources and transport processes of radionuclides in an SFR have been identified and characterized. This effort examines all stages of release and source term evolution, beginning with release from the fuel pin and ending with retention in containment. Radionuclide sources considered in this effort include releases originating both in-vessel (e.g. in-core fuel, primary sodium, cover gas cleanup system, etc.) and ex-vessel (e.g. spent fuel storage, handling, and movement). Releases resulting from a primary sodium fire are also considered as a potential source. For each release group, dominant transport phenomena are identified and qualitatively discussed. The key product of this effort was the development of concise, inclusive diagrams that illustrate the release and retention mechanisms at a high level, where unique schematics have been developed for in-vessel, ex-vessel and sodium fire releases. This review effort has also found that despite the substantial range of phenomena affecting radionuclide release, the

  16. ULI/UMTA (Urban Land Institute/Urban Mass Transportation Administration) Policy Forum of Joint Development of Rail-Transit Facilities

    SciTech Connect

    Dunphy, R.

    1987-01-01

    The ULI/UMTA Policy Forum on Joint Development of Rail Transit Facilities convened June 11-12, 1986. The participants included a representative group of developers, transit operators, local government officials, lenders, and public-interest groups concerned with transportation and urban development. Workshops at the forum elicited a consensus that UMTA should establish policies to advance, support, and reinforce joint development. They also recommended development of a set of guidelines that would address zoning and planning for density and traffic problems. It was also recommended that land-use changes at, near, or on development sites need to be made before construction begins, in part to preclude parties involved from changing their minds. The report includes general session presentations on the Hong Kong and Dulles DART projects, workshop summaries, and resource papers presented.

  17. Responsiveness of the National Eye Institute Visual Function Questionnaire to Progression to Advanced Age-Related Macular Degeneration, Vision Loss, and Lens Opacity

    PubMed Central

    2006-01-01

    Objective To describe the ability of the National Eye Institute Visual Function Questionnaire (NEI-VFQ) to detect meaningful change over time (responsiveness) to the primary Age-Related Eye Disease Study outcomes. Methods The 25-item NEI-VFQ plus appendix was administered at 2 visits at 1- to 4-year intervals to 4119 participants in the Age-Related Eye Disease Study. Events evaluated were progression to advanced age-related macular degeneration (AMD), visual acuity (VA) loss of at least 15 letters, and lens opacity progression. Responsiveness was measured by the t statistic, effect size (ES), responsiveness statistic, and area under the receiver operating characteristic curve. Variance components were used to estimate the contributions of events to variability of the NEI-VFQ score. Results Overall NEI-VFQ score was responsive to AMD progression (t = 14.0; P<.001; ES=0.81) and VA (t = 16.2; P<.001; ES=0.74). Mean changes ranged from 11 to 25 points for the subscales of general vision, near and distance activities, social functioning, mental health, role difficulties, dependency, and driving. The NEI-VFQ was unresponsive to lens opacity progression, although when the event occurred in the eye with the best vision at the first administration, the lens opacity ES was moderate for the color vision (ES = 0.62) and driving subscales (ES=0.66). Progression to advanced AMD and VA loss contributed significantly to the variation in the mean difference in overall VFQ score. Conclusions Changes in the NEI-VFQ overall and subscale scores of 10 points or more are associated with clinically significant changes in vision and AMD. This finding may assist the design of interventional studies of AMD and VA loss that include the NEI-VFQ as an outcome measure. PMID:16157800

  18. Jejunal microvilli atrophy and reduced nutrient transport in rats with advanced liver cirrhosis: improvement by Insulin-like Growth Factor I

    PubMed Central

    Castilla-Cortázar, Inma; Pascual, María; Urdaneta, Elena; Pardo, Javier; Puche, Juan Enrique; Vivas, Bárbara; Díaz-Casares, Amelia; García, María; Díaz-Sánchez, Matías; Varela-Nieto, Isabel; Castilla, Alberto; González-Barón, Salvador

    2004-01-01

    Background Previous results have shown that in rats with non-ascitic cirrhosis there is an altered transport of sugars and amino acids associated with elongated microvilli. These alterations returned to normal with the administration of Insulin-Like Growth Factor-I (IGF-I). The aims of this study were to explore the evolution of these alterations and analyse the effect of IGF-I in rats with advanced cirrhosis and ascites. Thus, jejunal structure and nutrient transport (D-galactose, L-leucine, L-proline, L-glutamic acid and L-cystine) were studied in rats with ascitic cirrhosis. Methods Advanced cirrhosis was induced by CCl4 inhalation and Phenobarbital administration for 30 weeks. Cirrhotic animals were divided into two groups which received IGF-I or saline during two weeks. Control group was studied in parallel. Jejunal microvilli were studied by electron microscopy. Nutrient transport was assessed in brush border membrane vesicles using 14C or 35S-labelled subtracts in the three experimental groups. Results Intestinal active Na+-dependent transport was significantly reduced in untreated cirrhotic rats. Kinetic studies showed a decreased Vmax and a reduced affinity for sugar and four amino acids transporters (expressed as an increased Kt) in the brush border membrane vesicles from untreated cirrhotic rats as compared with controls. Both parameters were normalised in the IGF-I-treated cirrhotic group. Electron microscopy showed elongation and fusion of microvilli with degenerative membrane lesions and/or notable atrophy. Conclusions The initial microvilli elongation reported in non ascitic cirrhosis develops into atrophy in rats with advanced cirrhosis and nutrient transports (monosaccharides and amino acids) are progressively reduced. Both morphological and functional alterations improved significantly with low doses of IGF-I. PMID:15196310

  19. Biochemical Bases for the Loss of Basipetal IAA Transport with Advancing Physiological Age in Etiolated Helianthus Hypocotyls: Changes in IAA Movement, Net IAA Uptake, and Phytotropin Binding.

    PubMed

    Suttle, J C

    1991-07-01

    Basipetal transport of [(14)C]IAA in hypocotyl segments isolated from various regions of etiolated Helianthus annuus L. cv NK 265 seedlings declines with increasing physiological age. This decline was the result of a reduction in both transport capacity and apparent velocity. Net IAA uptake was greater and the abilities of auxin transport inhibitors to stimulate net IAA uptake were reduced in older tissues. Net IAA accumulation by microsomal vesicles exhibited a similar behavior with respect to age. Specific binding of [(3)H]N-1-naphthylphthalamic acid (NPA) to microsomes prepared from young and older hypocotyl regions was saturable and consistent with a single class of binding sites. The apparent affinity constants for NPA binding in microsomes prepared from young versus older tissues were 6.4 and 10.8 nanomolar, respectively, and the binding site densities for young versus old tissues were 7.44 and 3.29 picomoles/milligram protein, respectively. Specific binding of [(3)H]NPA in microsomes prepared from both tissues displayed similar sensitivities toward unlabeled flurenol and exhibited only slight differences in sensitivity toward 2,3,5-triiodobenzoic acid. These results demonstrate that the progressive loss of basipetal IAA transport capacity in etiolated Helianthus hypocotyls with advancing age is associated with substantial alterations in the phytotropin-sensitive, IAA efflux system and they suggest that these changes are, at least partially, responsible for the observed reduction of polar IAA transport with advancing tissue age.

  20. 77 FR 34194 - Advance Notification to Native American Tribes of Transportation of Certain Types of Nuclear Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Part 71, ``Packaging and Transportation of Radioactive Material,'' for special form radioactive... and transportation of radioactive material and physical protection of plants and materials... in net weight of irradiated fuel, exclusive of cladding or other structural or packaging...

  1. 41 CFR 302-7.105 - May an advance of funds be authorized for transporting HHG and temporary storage?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... be authorized for transporting HHG and temporary storage? 302-7.105 Section 302-7.105 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 7-TRANSPORTATION AND TEMPORARY STORAGE OF HOUSEHOLD GOODS, PROFESSIONAL BOOKS,...

  2. State Institution "National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine" - research activities and scientific advance in 2014.

    PubMed

    Bazyka, D; Sushko, V; Chumak, A; Buzunov, V; Talko, V; Yanovich, L

    2015-12-01

    Research activities and scientific advance achieved in 2014 at the State Institution "National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine" (NRCRM) concerning medical problems of the Chornobyl disaster, radiation medicine, radiobiology, radiation hygiene and epidemiology in collaboration with the WHO network of medical preparedness and assistance in radiation accidents are outlined in the annual report.Epidemiological cohort studies found increased incidence (1990-2012 gg.) of thyroid cancer in victims of Chernobyl accident (liquidators - in 4.6 times, evacuated - in 4.0 times, residents of contaminated areas - in 1.3 times) and increased incidence of breast cancer in female workers of 1986-1987. (in the 1994-2012 biennium. SIR = 160,0%, 95% CI: 142,4-177,6). Retrospective studies of thyroid cancer ("case control") in cohorts and 152 thousand of liquidators were continued together with the US National Cancer Institute. Radiation risks of multiple myeloma and chronic lymphocytic leukemia were found.Molecular effects of remote period after radiation exposure include changes in gene expression TERF1, TERF2, CCND1, telomere length, the protein expression of cyclin D1, histone gamma H2AX. An association of molecular changes with cognitive deficits were defined. Genetic polymorphisms of rs2981582 gene FGFR2, rs12443621 gene TNRC9, rs3817198 gene LSP1, rs3803662 gene TNRC9, rs889312 gene MAP3K1 and their association with breast can cer were studied; the expression by tumor cells of estrogen and progesterone receptor, antigens of c kit, cytoker atins 5/6, TP53 and ki67, amplification status of the gene Her2 / neu, mutation status of the genes BRCA1 (muta tions 185delAG and 5382insC) and BRCA2 (mutation 6174delT) were studied. The possibility of persistence of radi ation modified hidden chromosomal instability in consecutive generations of human somatic cells was proven.The status of reproductive function and peculiarities

  3. OAST Space Theme Workshop. Volume 2: Theme summary. 6: Advanced transportation systems. A: Theme statement. B. 26 April 1976 presentation. C. Theme summary. D. Initiative actions

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Technology requirements for an integrated space transportation system capability which will allow the nation to use space efficiently, reliably, and routinely in the years between 1985 and 2000 with a significant return on invested resources will build on the currently defined space transportation system using shuttle, the IUS, and the advanced upper stage such as the solar electric propulsion system. Contributing technologies should include those which support (1) total reusability with minimal refurbishment; (2) responsiveness to high launch rate requirements when operation and energy are the predominant recurring costs; and (3) maximum flexibility in operation between earth and LEO and between LEO and GEO. Initiatives undertaken to advance the heavy lift to launch vehicles, single stage to orbit vehicles, and orbit transfer vehicles are listed.

  4. Comparison of the 3-D Deterministic Neutron Transport Code Attila® To Measure Data, MCNP And MCNPX For The Advanced Test Reactor

    SciTech Connect

    D. Scott Lucas; D. S. Lucas

    2005-09-01

    An LDRD (Laboratory Directed Research and Development) project is underway at the Idaho National Laboratory (INL) to apply the three-dimensional multi-group deterministic neutron transport code (Attila®) to criticality, flux and depletion calculations of the Advanced Test Reactor (ATR). This paper discusses the development of Attila models for ATR, capabilities of Attila, the generation and use of different cross-section libraries, and comparisons to ATR data, MCNP, MCNPX and future applications.

  5. Proceedings of the NATO-Advanced Study Institute on Computer Aided Analysis of Rigid and Flexible Mechanical Systems. Volume 1: Main lectures

    NASA Astrophysics Data System (ADS)

    Pereira, Manuel S.; Ambrosio, Jorge A. C.

    1993-07-01

    During the last few years, major scientific progress has been achieved in fields related to computer aided analysis of multibody systems. In view of this progress and recent developments of computer hardware and general purpose software, there is a need to access the current state of art and results from different schools of thought, with the objective of focussing trends in future research. Going back to 1983 when an important NATO-NSF-ARO Advanced Study Institute on Computer Aided Analysis and Optimization of Mechanical Systems was held at the University of Iowa, one may notice that less then 10 years ago the state of art was mainly dwelling on rigid body dynamics. The interest in the dynamic simulation of mechanical systems has steadily increased in recent years coming mainly from the aerospace and automative industries. The development of multibody system analysis formulations have been more recently motivated with the need to include several features such as: real-time simulation capabilities, highly non-linear control devices, work space path planing, active control of machine flexibilities and reliability and accuracy in the analysis results. The need for accurate and efficient analysis tools for design of large and lightweight mechanical systems has driven many research groups in the challenging problem of flexible systems with an increasing interaction with finite element methodologies. Basic approaches to mechanical systems dynamic analysis have recently been presented in several new text books. These publications demonstrate that both recursive and absolute methods still have their proponents to resolve the redundancy encountered in most mechanical systems.

  6. The advanced launch system: Application of total quality management principles to low-cost space transportation system development

    NASA Astrophysics Data System (ADS)

    Wolfe, M. G.; Rothwell, T. G.; Rosenberg, D. A.; Oliver, M. B.

    Recognizing that a major inhibitor of man's rapid expansion of the use of space is the high cost (direct and induced) of space transportation, the U.S. has embarked on a major national program to radically reduce the cost of placing payloads into orbit while, at the same time, making equally radical improvements inlaunch system operability. The program is entitled "The Advanced Launch System" (ALS) and is a joint Department of Defense/National Aeronautics and Space Administration (DoD/NASA) program which will provide launch capability in the post 2000 timeframe. It is currently in Phase II (System Definition), which began in January 1989, and will serve as a major source of U.S. launch system technology over the next several years. The ALS is characterized by a new approach to space system design, development, and operation. The practices that are being implemented by the ALS are expected to affect the management and technical operation of all future launch systems. In this regard, the two most significant initiatives being implemented on the ALS program are the practices of Total Quality Management (TQM) and the Unified Information System (Unis). TQM is a DoD initiative to improve the quality of the DoD acquisition system, contractor management systems, and the technical disciplines associated with the design, development, and operation of major systems. TQM has been mandated for all new programs and affects the way every group within the system currently does business. In order to implement the practices of TQM, new methods are needed. A program on the scale of the ALS generates vast amounts of information which must be used effectively to make sound decisions. Unis is an information network that will connect all ALS participants throughout all phases of the ALS development. Unis is providing support for project management and system design, and in following phases will provide decision support for launch operations, computer integrated manufacturing, automated

  7. Advanced reactors and novel reactions for the conversion of triglyceride based oils into high quality renewable transportation fuels

    NASA Astrophysics Data System (ADS)

    Linnen, Michael James

    Sustainable energy continues to grow more important to all societies, leading to the research and development of a variety of alternative and renewable energy technologies. Of these, renewable liquid transportation fuels may be the most visible to consumers, and this visibility is further magnified by the long-term trend of increasingly expensive petroleum fuels that the public consumes. While first-generation biofuels such as biodiesel and fuel ethanol have been integrated into the existing fuel infrastructures of several countries, the chemical differences between them and their petroleum counterparts reduce their effectiveness. This gives rise to the development and commercialization of second generation biofuels, many of which are intended to have equivalent properties to those of their petroleum counterparts. In this dissertation, the primary reactions for a second-generation biofuel process, known herein as the University of North Dakota noncatalytic cracking process (NCP), have been studied at the fundamental level and improved. The NCP is capable of producing renewable fuels and chemicals that are virtually the same as their petroleum counterparts in performance and quality (i.e., petroleum-equivalent). In addition, a novel analytical method, FIMSDIST was developed which, within certain limitations, can increase the elution capabilities of GC analysis and decrease sample processing times compared to other high resolution methods. These advances are particularly useful for studies of highly heterogeneous fuel and/or organic chemical intermediates, such as those studied for the NCP. However the data from FIMSDIST must be supplemented with data from other methods such as for certain carboxylic acid, to provide accurate, comprehensive results, From a series of TAG cracking experiments that were performed, it was found that coke formation during cracking is most likely the result of excessive temperature and/or residence time in a cracking reactor. Based on this

  8. Report on the Program “Fluid-mediated particle transport in geophysical flows” at the Kavli Institute for Theoretical Physics, UC Santa Barbara, September 23 to December 12, 2013

    SciTech Connect

    Jenkins, James T.; Meiburg, Eckart; Valance, Alexandre

    2015-09-15

    The Kavli Institute of Theoretical Physics (KITP) program held at UC Santa Barbara in the fall of 2013 addressed the dynamics of dispersed particulate flows in the environment. By focusing on the prototypes of aeolian transport and turbidity currents, it aimed to establish the current state of our understanding of such two-phase flows, to identify key open questions, and to develop collaborative research strategies for addressing these questions. Here, we provide a brief summary of the program outcome.

  9. An Advanced Integrated Diffusion/Transport Method for the Design, Analysis and Optimization of the Very-High-Temperature Reactors

    SciTech Connect

    Farzad Rahnema; Dingkang Zhang; Abderrafi Ougouag; Frederick Gleicher

    2011-04-04

    The main objective of this research is to develop an integrated diffusion/transport (IDT) method to substantially improve the accuracy of nodal diffusion methods for the design and analysis of Very High Temperature Reactors (VHTR). Because of the presence of control rods in the reflector regions in the Pebble Bed Reactor (PBR-VHTR), traditional nodal diffusion methods do not accurately model these regions, within which diffusion theory breaks down in the vicinity of high neutron absorption and steep flux gradients. The IDT method uses a local transport solver based on a new incident flux response expansion method in the controlled nodes. Diffusion theory is used in the rest of the core. This approach improves the accuracy of the core solution by generating transport solutions of controlled nodes while maintaining computational efficiency by using diffusion solutions in nodes where such a treatment is sufficient. The transport method is initially developed and coupled to the reformulated 3-D nodal diffusion model in the CYNOD code for PBR core design and fuel cycle analysis. This method is also extended to the prismatic VHTR. The new method accurately captures transport effects in highly heterogeneous regions with steep flux gradients. The calculations of these nodes with transport theory avoid errors associated with spatial homogenization commonly used in diffusion methods in reactor core simulators

  10. Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2018-2020 Period Phase 2

    NASA Technical Reports Server (NTRS)

    Morgenstern, John; Buonanno, Michael; Yao, Jixian; Murugappan, Mugam; Paliath, Umesh; Cheung, Lawrence; Malcevic, Ivan; Ramakrishnan, Kishore; Pastouchenko, Nikolai; Wood, Trevor; Martens, Steve; Viars, Phil; Tersmette, Trevor; Lee, Jason; Simmons, Ron; Plybon, David; Alonso, Juan; Palacios, Francisco; Lukaczyk, Trent; Carrier, Gerald

    2015-01-01

    Lockheed Martin Aeronautics Company (LM), working in conjunction with General Electric Global Research (GE GR) and Stanford University, executed a 19 month program responsive to the NASA sponsored "N+2 Supersonic Validation: Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2018-2020 Period" contract. The key technical objective of this effort was to validate integrated airframe and propulsion technologies and design methodologies necessary to realize a supersonic vehicle capable of meeting the N+2 environmental and performance goals. The N+2 program is aligned with NASA's Supersonic Project and is focused on providing system level solutions capable of overcoming the efficiency, environmental, and performance barriers to practical supersonic flight. The N+2 environmental and performance goals are outlined in the technical paper, AIAA-2014-2138 (Ref. 1) along with the validated N+2 Phase 2 results. Our Phase 2 efforts built upon our Phase 1 studies (Ref. 2) and successfully demonstrated the ability to design and test realistic configurations capable of shaped sonic booms over the width of the sonic boom carpet. Developing a shaped boom configuration capable of meeting the N+2 shaped boom targets is a key goal for the N+2 program. During the LM Phase 1 effort, LM successfully designed and tested a shaped boom trijet configuration (1021) capable of achieving 85 PLdB under track (forward and aft shock) and up to 28 deg off-track at Mach 1.6. In Phase 2 we developed a refined configuration (1044-2) that extended the under 85 PLdB sonic boom level over the entire carpet of 52 deg off-track at a cruise Mach number of 1.7. Further, the loudness level of the configuration throughout operational conditions calculates to an average of 79 PLdB. These calculations rely on propagation employing Burger's (sBOOM) rounding methodology, and there are indications that the configuration average loudness would actually be 75 PLdB. We also added

  11. Space Shuttle: Status of advanced solid rocket motor program. Report to the Chair, Subcommittee on Government Activities and Transportation, Committee on Government Operations, House of Representatives

    NASA Astrophysics Data System (ADS)

    1992-11-01

    The Advanced Solid Rocket Motor is one of the National Aeronautics and Space Administration's (NASA) most expensive and controversial programs. Two reusable solid rocket motors are attached to the Space Shuttle to provide most of the thrust needed to lift it into orbit. The advanced motor is being designed to replace the current motor, which is a redesigned version of the motor that caused the January 1986 Challenger accident. The Chair of the Subcommittee on Government Activities and Transportation, House Committee on Government Operations, requested that GAO review the program's status. The specific objectives were to: (1) assess the extent to which the need for the program has changed; and (2) determine the reasons for cost growth and schedule slippage.

  12. Final Report for the Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period, N+3 Supersonic Program

    NASA Technical Reports Server (NTRS)

    Morgenstern, John; Norstrud, Nicole; Stelmack, Marc; Skoch, Craig

    2010-01-01

    The N+3 Final Report documents the work and progress made by Lockheed Martin Aeronautics in response to the NASA sponsored program "N+3 NRA Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period." The key technical objective of this effort was to generate promising supersonic concepts for the 2030 to 2035 timeframe and to develop plans for maturing the technologies required to make those concepts a reality. The N+3 program is aligned with NASA's Supersonic Project and is focused on providing alternative system-level solutions capable of overcoming the efficiency, environmental, and performance barriers to practical supersonic flight

  13. Transport Phenomena.

    ERIC Educational Resources Information Center

    Shah, D. B.

    1984-01-01

    Describes a course designed to achieve a balance between exposing students to (1) advanced topics in transport phenomena, pointing out similarities and differences between three transfer processes and (2) common methods of solving differential equations. (JN)

  14. Great Lakes Energy Institute

    SciTech Connect

    Alexander, J. Iwan

    2012-11-18

    The vision of the Great Lakes Energy Institute is to enable the transition to advanced, sustainable energy generation, storage, distribution and utilization through coordinated research, development, and education. The Institute will place emphasis on translating leading edge research into next generation energy technology. The Institute’s research thrusts focus on coordinated research in decentralized power generation devices (e.g. fuel cells, wind turbines, solar photovoltaic devices), management of electrical power transmission and distribution, energy storage, and energy efficiency.

  15. Can You Hear Us Now? A White Paper on Connecting Minority-Serving Institutions in the West to U.S. Advanced Cyberinfrastructure. Lariat Summit on Minority Institutions and Cyberinfrastructure in the West (Bozeman, Montana, August 14-15, 2006)

    ERIC Educational Resources Information Center

    Fox, Louis

    2007-01-01

    Advanced information, communication, computation and collaboration technologies, known as "cyberinfrastructure," have become essential elements for research, education, and innovation in the 21st century. A major challenge confronting the United States today is how to ensure that all colleges and universities, including those that have…

  16. 75 FR 75641 - Advance Notification to Native American Tribes of Transportation of Certain Types of Nuclear Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-06

    ... that govern packaging and transportation of radioactive material and physical protection of plants and..., exclusive of cladding or other structural or packaging material, which has a total external radiation dose... form radioactive material; (2) 3000 times the A 2 value of the radionuclides as specified in Appendix...

  17. Advances in colloid and biocolloid transport in porous media: particle size-dependent dispersivity and gravity effects

    NASA Astrophysics Data System (ADS)

    Chrysikopoulos, Constantinos V.; Manariotis, Ioannis D.; Syngouna, Vasiliki I.

    2014-05-01

    Accurate prediction of colloid and biocolloid transport in porous media relies heavily on usage of suitable dispersion coefficients. The widespread procedure for dispersion coefficient determination consists of conducting conservative tracer experiments and subsequently fitting the collected breakthrough data with a selected advection-dispersion transport model. The fitted dispersion coefficient is assumed to characterize the porous medium and is often used thereafter to analyze experimental results obtained from the same porous medium with other solutes, colloids, and biocolloids. The classical advection-dispersion equation implies that Fick's first law of diffusion adequately describes the dispersion process, or that the dispersive flux is proportional to the concentration gradient. Therefore, the above-described procedure inherently assumes that the dispersive flux of all solutes, colloids and biocolloids under the same flow field conditions is exactly the same. Furthermore, the available mathematical models for colloid and biocoloid transport in porous media do not adequately account for gravity effects. Here an extensive laboratory study was undertaken in order to assess whether the dispersivity, which traditionally has been considered to be a property of the porous medium, is dependent on colloid particle size, interstitial velocity and length scale. The breakthrough curves were successfully simulated with a mathematical model describing colloid and biocolloid transport in homogeneous, water saturated porous media. The results demonstrated that the dispersivity increases very slowly with increasing interstitial velocity, and increases with column length. Furthermore, contrary to earlier results, which were based either on just a few experimental observations or experimental conditions leading to low mass recoveries, dispersivity was positively correlated with colloid particle size. Also, transport experiments were performed with biocolloids (bacteriophages:

  18. Flight service evaluation of an advanced composite empennage component on commercial transport aircraft. Phase 1: Engineering development

    NASA Technical Reports Server (NTRS)

    Ary, A.; Axtell, C.; Fogg, L.; Jackson, A.; James, A. M.; Mosesian, B.; Vanderwier, J.; Vanhamersveld, J.

    1976-01-01

    The empennage component selected for this program is the vertical fin box of the L-1011 aircraft. The box structure extends from the fuselage production joint to the tip rib and includes the front and rear spars. Various design options were evaluated to arrive at a configuration which would offer the highest potential for satisfying program objectives. The preferred configuration selected consists of a hat-stiffened cover with molded integrally stiffened spars, aluminum trussed composite ribs, and composite miniwich web ribs with integrally molded caps. Material screening tests were performed to select an advanced composite material system for the Advanced Composite Vertical Fin (ACFV) that would meet the program requirements from the standpoint of quality, reproducibility, and cost. Preliminary weight and cost analysis were made, targets established, and tracking plans developed. These include FAA certification, ancillary test program, quality control, and structural integrity control plans.

  19. NATO-Advances Study Institute, Diamond and Diamond-Like Films and Coatings, Held in Il Ciocco, Castelvecchio Pascoli, Italy on July 22-August 3, 1990

    DTIC Science & Technology

    1990-08-03

    39-690021279 FAX: 39-690021243 Dr. Alessandro Bellone Olivetti Office Via Jervis 20 10015 Ivres (Turin), Italy Phone: FAX: 39-125528116 Mr. Antonio...delle Volta , 94 1-25129 Bresua, Italy Phone: 39-30-347491 FAX: 39-30-342906 Prof. Masao Murakawa Nippon Institute of Technology 4-1 Gakuendai Miyashiro

  20. Financial Management in Higher Education: An Approach to Improvement. Advanced Institutional Development Program (AIDP) Two-year College Consortium, Vol. II, No. 3.

    ERIC Educational Resources Information Center

    Listou, Robert E.

    Defining financial management as the provision of financial data for, and the use of that data in, the planning, management, and evaluation functions of an institution, this document suggests an approach to improvement in the provision of financial data. A series of five cost sheets are presented which allow for cost calculations at differing…

  1. Institute news

    NASA Astrophysics Data System (ADS)

    1999-11-01

    celebrate the Group's 50th anniversary by examining what has been done, focusing on why and how it was done, with lessons and ambitions for the future. The meeting will be held at Institute Headquarters and the programme is as follows: 10.45 - 11.00 Welcome and introduction (Philip Britton: Chair of the Education Group) 11.00 - 11.45 Examinations and assessment through the ages (Tim Akrill, Chief Examiner for A-level Physics with Edexcel) 11.45 - 12.30 Curriculum reform in physics, past, present and future (Professor Jon Ogborn, Director of the Post-16 Physics Initiative) 14.00 - 14.15 Physics education and the Institute of Physics, some personal reflections (speaker to be announced) 14.15 - 15.00 Connecting with Advancing Physics: the first year in HE physics (Professor Mick Brown, University of Cambridge) 15.15 - 15.35 Physics education, the next 50 years! (Ken Dobson, Honorary Editor of Physics Education) The day should hold something for everyone, so reserve your place if you can. Schools and Colleges lecture Dr Zbig Sobiesierski of the University of the West of England is the 1999 - 2000 Institute of Physics Schools and Colleges lecturer, touring the country with his talk `Seeing is believing?'. He will demonstrate the different physical ways in which we can both make and mix colour and will then proceed to discuss why our eyes respond to light in the way they do. The lecture will be aimed primarily at students aged 14 and above, but it will also be suitable for older audiences. The intention, as with previous series, will be to show the relevance of the physics concepts to the members of the audience and the world in which they live. To find out more about the lecture in your area and to make a booking, contact should be made with the local organizer (full details of the list can be obtained from Catherine Wilson at Institute Headquarters). The dates and venues planned so far are as follows: 1 Nov: Northern College, Aberdeen 2 Nov: University of St Andrews 3 Nov

  2. Activities of the Institute for Mechanical Engineering

    NASA Astrophysics Data System (ADS)

    The Institute of Mechanical Engineering (IME) is part of Canada's National Research Council. Its mission is to undertake, support, promote, and disseminate research and development in the mechanical engineering aspects of three vital sectors of the Canadian economy: transportation, resource industries, and manufacturing. The IME achieves its mission by performing research and development in its own facilities; by developing, providing, and transferring expertise and knowledge; by making its research facilities available to collaborators and clients; and by participating in international liaison and collaborative research activities. Six research programs are conducted in the IME: Advanced Manufacturing Technology; Coastal Zone Engineering; Cold Regions Engineering; Combustion and Fluids Engineering; Ground Transportation Technology; and Machinery and Engine Technology. The rationale and major research thrusts of each program are described, and specific achievements in 1991-92 are reviewed. Lists of technical reports and papers presented by IME personnel are also included.

  3. Institution Closures.

    ERIC Educational Resources Information Center

    Hayden, Mary F., Ed.; And Others

    1995-01-01

    This newsletter theme issue focuses on the need to accelerate the closing of institutions for people with mental retardation. Articles are by both current and former residents of institutions and by professionals, and include: "The Realities of Institutions" (Tia Nelis); "I Cry Out So That I Won't Go Insane" (Mary F. Hayden); "Trends in…

  4. Does Model Development Ahead of Data Collection Have Merit? A Case for Advancing Non-Local Fluvial Transport Theories

    NASA Astrophysics Data System (ADS)

    Voller, V. R.; Falcini, F.; Foufoula-Georgiou, E.; Ganti, V.; Paola, C.; Hill, K. M.; Swenson, J. B.; Longjas, A.

    2013-12-01

    The purpose of this work is to suggest how experiments might be constructed to provide data to test recently proposed phenomenological non-local model of depositional transport; formulated on the basis of morphological arguments but with limited data. A sound methodology for developing models of geological systems is to first collect significant data and then carefully identify an appropriate model form and parameters. An alternative approach is to construct what might be referred to as a phenomenological model, where limited observation of the system is used to suggest an appropriate mathematical form that matches the critical nature of the physical system behavior. By their nature, phenomenological models are often developed within a fairly narrow range of observations. In this way, interesting findings can occur when the models are modified and exercised across wider physical domains, in particular in domains where there is an absence of hard data to corroborate or invalidate the model predictions. Although this approach might be frown on my some, it is important to recognize the stellar and proven track record of phenomenological models, which despite the original scarcity of data, often pave the way to new perspectives and important findings. The poster child example is the Higgs boson. In the early 60's manipulation of the quantum field equations revealed a critical inconsistency related to the masses of fundamental particles that could only be mathematically resolved by assuming that they operated within a field that would exert drag; this conjecture took almost fifty years and the vast experimental operation of the Large Hadron Collider to physically confirm. In this work we examine a current phenomenological model used to describe non-local transport in fluvial sediment domains. This model has its genesis in attempting to describe the shapes of hill slope profiles, while acknowledging the fact that two points of the landscape with the same local slope are

  5. Long-term Follow-up Results of a Multi-institutional Phase 2 Study of Concurrent Chemoradiation Therapy for Locally Advanced Cervical Cancer in East and Southeast Asia

    SciTech Connect

    Kato, Shingo; Ohno, Tatsuya; Thephamongkhol, Kullathorn; Chansilpa, Yaowalak; Cao, Jianping; Xu, Xiaoting; Devi, C. R. Beena; Swee, Tang Tieng; Calaguas, Miriam J.C.; Reyes, Rey H. de los; Cho, Chul-Koo; Dung, To Anh; Supriana, Nana; Erawati, Dyah; Mizuno, Hideyuki; Nakano, Takashi; Tsujii, Hirohiko

    2013-09-01

    Purpose: To report the long-term survival and toxicity of a multi-institutional phase 2 study of concurrent chemoradiation therapy (CCRT) for locally advanced cervical cancer in east and southeast Asia. Methods and Materials: Ten institutions from 8 Asian countries participated in the study. Between April 2003 and March 2006, 120 patients (60 with bulky stage IIB and 60 with stage IIIB) were treated with CCRT. Radiation therapy consisted of pelvic external beam radiation therapy and either high-dose-rate or low-dose-rate intracavitary brachytherapy. Five cycles of weekly cisplatin (40 mg/m{sup 2}) were administered during the course of radiation therapy. Treatment results were evaluated by the rates of local control, overall survival, and late toxicities. Results: Median follow-up was 63.7 months, and the follow-up rate at 5 years was 98%. The 5-year local control and overall survival rates for all patients were 76.8% and 55.1%, respectively. The 5-year rates of major late toxicities of the rectum and bladder were 7.9% and 0%, respectively. Conclusions: The long-term results have suggested that CCRT is safe and effective for patients with locally advanced cervical cancer in east and southeast Asia. However, further efforts are needed to improve overall survival.

  6. Impact of Institutional Care on Attachment Disorganization and Insecurity of Ukrainian Preschoolers: Protective Effect of the Long Variant of the Serotonin Transporter Gene (5HTT)

    ERIC Educational Resources Information Center

    Bakermans-Kranenburg, Marian J.; Dobrova-Krol, Natasha; van IJzendoorn, Marinus

    2012-01-01

    Institutional care has been shown to lead to insecure and disorganized attachments and indiscriminate friendliness. Some children, however, are surprisingly resilient to the adverse environment. Here the protective role of the long variant of the serotonin receptor gene (5HTT) is explored in a small hypothesis-generating study of 37 Ukrainian…

  7. Evaluation of Flying Qualities and Guidance Displays for an Advanced Tilt-Wing STOL Transport Aircraft in Final Approach and Landing

    NASA Technical Reports Server (NTRS)

    Frost, Chad R.; Franklin, James A.; Hardy, Gordon H.

    2002-01-01

    A piloted simulation was performed on the Vertical Motion Simulator at NASA Ames Research Center to evaluate flying qualities of a tilt-wing Short Take-Off and Landing (STOL) transport aircraft during final approach and landing. The experiment was conducted to assess the design s handling qualities, and to evaluate the use of flightpath-centered guidance for the precision approach and landing tasks required to perform STOL operations in instrument meteorological conditions, turbulence, and wind. Pilots rated the handling qualities to be satisfactory for all operations evaluated except those encountering extreme crosswinds and severe windshear; even in these difficult meteorological conditions, adequate handling qualities were maintained. The advanced flight control laws and guidance displays provided consistent performance and precision landings.

  8. Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human.

    PubMed

    Sato, Masaya; Ikeda, Hitoshi; Uranbileg, Baasanjav; Kurano, Makoto; Saigusa, Daisuke; Aoki, Junken; Maki, Harufumi; Kudo, Hiroki; Hasegawa, Kiyoshi; Kokudo, Norihiro; Yatomi, Yutaka

    2016-08-26

    The role of sphingosine 1-phosphate (S1P) in liver fibrosis or inflammation was not fully examined in human. Controversy exists which S1P receptors, S1P1 and S1P3 vs S1P2, would be importantly involved in its mechanism. To clarify these matters, 80 patients who received liver resection for hepatocellular carcinoma and 9 patients for metastatic liver tumor were enrolled. S1P metabolism was analyzed in background, non-tumorous liver tissue. mRNA levels of sphingosine kinase 1 (SK1) but not SK2 were increased in livers with fibrosis stages 3-4 compared to those with 0-2 and to normal liver. However, S1P was not increased in advanced fibrotic liver, where mRNA levels of S1P transporter spinster homolog 2 (SPNS2) but not S1P-degrading enzymes were enhanced. Furthermore, mRNA levels of S1P2 but not S1P1 or S1P3 were increased in advanced fibrotic liver. These increased mRNA levels of SK1, SPNS2 and S1P2 in fibrotic liver were correlated with α-smooth muscle actin mRNA levels in liver, and with serum ALT levels. In conclusion, S1P may be actively generated, transported to outside the cells, and bind to its specific receptor in human liver to play a role in fibrosis or inflammation. Altered S1P metabolism in fibrotic liver may be their therapeutic target.

  9. Conceptual study of an advanced supersonic technology transport (AST-107) for transpacific range using low-bypass-ratio turbofan engines

    NASA Technical Reports Server (NTRS)

    Morris, S. J., Jr.; Foss, W. E., Jr.; Neubauer, M. J., Jr.

    1980-01-01

    An advanced supersonic technology configuration concept designated the AST-107, using a low bypass ratio turbofan engine, is described and analyzed. The aircraft had provisions for 273 passengers arranged five abreast. The cruise Mach number was 2.62. The mission range for the AST-107 was 8.48 Mm (4576 n.mi.) and an average lift drag ratio of 9.15 during cruise was achieved. The available lateral control was not sufficient for the required 15.4 m/s (30 kt) crosswind landing condition, and a crosswind landing gear or a significant reduction in dihedral effect would be necessary to meet this requirement. The lowest computed noise levels, including a mechanical suppressor noise reduction of 3 EPNdB at the flyover and sideline monitoring stations, were 110.3 EPNdB (sideline noise), 113.1 EPNdB (centerline noise) and 110.5 EPNdB (approach noise).

  10. Integrative application of active controls (IAAC) technology to an advanced subsonic transport project. Initial act configuration design study

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The performance and economic benefits of a constrained application of Active Controls Technology (ACT) are identified, and the approach to airplane design is established for subsequent steps leading to the development of a less constrained final ACT configuration. The active controls configurations are measured against a conventional baseline configuration, a state-of-the-art transport, to determine whether the performance and economic changes resulting from ACT merit proceeding with the project. The technology established by the conventional baseline configuration was held constant except for the addition of ACT. The wing, with the same planform, was moved forward on the initial ACT configuration to move the loading range aft relative to the wing mean aerodynamic chord. Wing trailing-edge surfaces and surface controls also were reconfigured for load alleviation and structural stabilization.

  11. N plus 3 Advanced Concept Studies for Supersonic Commercial Transport Aircraft Entering Service in the 2030-2035 Period

    NASA Technical Reports Server (NTRS)

    Welge, H. Robert; Bonet, John; Magee, Todd; Tompkins, Daniel; Britt, Terry R.; Nelson, Chet; Miller, Gregory; Stenson, Douglas; Staubach, J. Brent; Bala, Naushir; Duge, Robert; OBrien, Mark; Cedoz, Robert; Barlow, Andrew; Martins, Steve; Viars, Phil; Rasheed, Adam; Kirby, Michelle; Raczynski, Chris; Roughen, Kevin; Doyle, Steven; Alston, Katherine; Page, Juliet; Plotkin, Kenneth J.

    2011-01-01

    Boeing, with Pratt & Whitney, General Electric, Rolls-Royce, M4 Engineering, Wyle Laboratories and Georgia Institute of Technology, conducted a study of supersonic commercial aircraft concepts and enabling technologies for the year 2030-2035 timeframe. The work defined the market and environmental/regulatory conditions that could evolve by the 2030/35 time period, from which vehicle performance goals were derived. Relevant vehicle concepts and technologies are identified that are anticipated to meet these performance and environmental goals. A series of multidisciplinary analyses trade studies considering vehicle sizing, mission performance and environmental conformity determined the appropriate concepts. Combinations of enabling technologies and the required technology performance levels needed to meet the desired goals were identified. Several high priority technologies are described in detail, including roadmaps with risk assessments that outline objectives, key technology challenges, detailed tasks and schedules and demonstrations that need to be performed. A representative configuration is provided for reference purposes, along with associated performance estimates based on these key technologies.

  12. Capture and Transport of Laser Accelerated Protons by Pulsed Magnetic Fields: Advancements Toward Laser-Based Proton Therapy

    NASA Astrophysics Data System (ADS)

    Burris-Mog, Trevor J.

    might look like. A theoretical beam transport system is presented at the end of this dissertation. It shows us that pulse power magnetic optics generating reasonable field strengths can transport a large bandwidth, high kinetic energy proton beam around and into a patient. This gives us insight into the spectrum available per laser pulse at the exit-port of the gantry as well as what types of dose deposition routines and spectral shaping techniques will need to be developed to contour a given dose to a given tumor volume.

  13. Advanced Control Algorithms for Compensating the Phase Distortion Due to Transport Delay in Human-Machine Systems

    NASA Technical Reports Server (NTRS)

    Guo, Liwen; Cardullo, Frank M.; Kelly, Lon C.

    2007-01-01

    The desire to create more complex visual scenes in modern flight simulators outpaces recent increases in processor speed. As a result, simulation transport delay remains a problem. New approaches for compensating the transport delay in a flight simulator have been developed and are presented in this report. The lead/lag filter, the McFarland compensator and the Sobiski/Cardullo state space filter are three prominent compensators. The lead/lag filter provides some phase lead, while introducing significant gain distortion in the same frequency interval. The McFarland predictor can compensate for much longer delay and cause smaller gain error in low frequencies than the lead/lag filter, but the gain distortion beyond the design frequency interval is still significant, and it also causes large spikes in prediction. Though, theoretically, the Sobiski/Cardullo predictor, a state space filter, can compensate the longest delay with the least gain distortion among the three, it has remained in laboratory use due to several limitations. The first novel compensator is an adaptive predictor that makes use of the Kalman filter algorithm in a unique manner. In this manner the predictor can accurately provide the desired amount of prediction, while significantly reducing the large spikes caused by the McFarland predictor. Among several simplified online adaptive predictors, this report illustrates mathematically why the stochastic approximation algorithm achieves the best compensation results. A second novel approach employed a reference aircraft dynamics model to implement a state space predictor on a flight simulator. The practical implementation formed the filter state vector from the operator s control input and the aircraft states. The relationship between the reference model and the compensator performance was investigated in great detail, and the best performing reference model was selected for implementation in the final tests. Theoretical analyses of data from offline

  14. Advanced transportation system studies technical area 2(TA-2): Heavy lift launch vehicle development. volume 1; Executive summary

    NASA Technical Reports Server (NTRS)

    McCurry, J.

    1995-01-01

    The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 1, provides a summary description of the technical activities that were performed over the entire contract duration, covering three distinct launch vehicle definition activities: heavy-lift (300,000 pounds injected mass to low Earth orbit) launch vehicles for the First Lunar Outpost (FLO), medium-lift (50,000-80,000 pounds injected mass to low Earth orbit) launch vehicles, and single-stage-to-orbit (SSTO) launch vehicles (25,000 pounds injected mass to a Space Station orbit).

  15. Advanced transportation system studies technical area 2 (TA-2): Heavy lift launch vehicle development. volume 3; Program Cost estimates

    NASA Technical Reports Server (NTRS)

    McCurry, J. B.

    1995-01-01

    The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. The basic period of performance of the TA-2 contract was from May 1992 through May 1993. No-cost extensions were exercised on the contract from June 1993 through July 1995. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 3, provides a work breakdown structure dictionary, user's guide for the parametric life cycle cost estimation tool, and final report developed by ECON, Inc., under subcontract to Lockheed Martin on TA-2 for the analysis of heavy lift launch vehicle concepts.

  16. Integrated application of active controls (IAAC) technology to an advanced subsonic transport project. Initial ACT configuration design study

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The initial ACT configuration design task of the integrated application of active controls (IAAC) technology project within the Energy Efficient Transport Program is summarized. A constrained application of active controls technology (ACT) resulted in significant improvements over a conventional baseline configuration previously established. The configuration uses the same levels of technology, takeoff gross weight, payload, and design requirements/objectives as the baseline, except for flying qualities, flutter, and ACT. The baseline wing is moved forward 1.68 m. The configuration incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 45% reduction in horizontal tail size), lateral/directional-augmented stability, an angle of attack limiter, wing load alleviation, and flutter mode control. This resulted in a 930 kg reduction in airplane operating empty weight and a 3.6% improvement in cruise efficiency, yielding a 13% range increase. Adjusted to the 3590 km baseline mission range, this amounts to 6% block fuel reduction and a 15.7% higher incremental return on investment, using 1978 dollars and fuel cost.

  17. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Wing planform study and final configuration selection

    NASA Technical Reports Server (NTRS)

    1981-01-01

    This report summarizes the Wing Planform Study Task and Final Configuration Selection of the Integrated Application of Active Controls (IAAC) Technology Project within the Energy Efficient Transport Program. Application of Active Controls Technology (ACT) in combination with increased wing span resulted in significant improvements over the Conventional Baseline Configuration (Baseline) and the Initial ACT Configuration previously established. The configurations use the same levels of technology (except for ACT), takeoff gross weight, and payload as the Baseline. The Final ACT Configuration (Model 768-107) incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 45% reduction in horizontal tail sizes), lateral/directional-augmented stability, an angle-of-attack limiter, and wing-load alleviation. Flutter-mode control was not beneficial for this configuration. This resulted in an 890 kg (1960 lb) reduction in airplane takeoff gross weight and a 9.8% improvement in cruise lift/drag. At the Baseline mission range (3590 km) (1938 nmi), this amounts to 10% block fuel reduction. Good takeoff performance at high-altitude airports on a hot day was also achieved. Results of this task strongly indicate that the IAAC Project should proceed with the Final ACT evaluation and begin the required control system development and testing.

  18. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Wing planform study and final configuration selection

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The Wing Planform Study and Final Configuration Selection Task of the Integrated Application of Active Controls (IAAC) Technology Project within the Energy Efficient Transport Program is documented. Application of Active Controls Technology (ACT) in combination with increased wing span resulted in significant improvements over the Conventional Baseline Configuration (Baseline) and the Initial ACT Configuration previously established. The configurations use the same levels of technology, takeoff gross weight, and payload as the Baseline. The Final ACT Configuration (Model 768-107) incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 44% reduction in horizontal tail size), lateral/directional-augmented stability, an angle-of-attack limiter, and wing-load alleviation. Flutter-mode control was not beneficial for this configuration. This resulted in an 890 kg (1960 lb) reduction in airplane takeoff gross weight and a 9.8% improvement in cruise lift/drag. At the Baseline mission range (3589 km 1938 nmi), this amounts to 10% block-fuel reduction. Results of this task strongly indicate that the IAAC Project should proceed with the Final ACT evaluation, and begin the required control system development and test.

  19. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Final ACT configuration evaluation

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The Final ACT Configuration Evaluation Task of the Integrated Application of Active Controls (IAAC) technology project within the energy efficient transport program is summarized. The Final ACT Configuration, through application of Active Controls Technology (ACT) in combination with increased wing span, exhibits significant performance improvements over the conventional baseline configuration. At the design range for these configurations, 3590 km, the block fuel used is 10% less for the Final ACT Configuration, with significant reductions in fuel usage at all operational ranges. Results of this improved fuel usage and additional system and airframe costs and the complexity required to achieve it were analyzed to determine its economic effects. For a 926 km mission, the incremental return on investment is nearly 25% at 1980 fuel prices. For longer range missions or increased fuel prices, the return is greater. The technical risks encountered in the Final ACT Configuration design and the research and development effort required to reduce these risks to levels acceptable for commercial airplane design are identified.

  20. Phase II multi-institutional prospective randomised trial comparing S-1+paclitaxel with S-1+cisplatin in patients with unresectable and/or recurrent advanced gastric cancer

    PubMed Central

    Mochiki, E; Ogata, K; Ohno, T; Toyomasu, Y; Haga, N; Fukai, Y; Aihara, R; Ando, H; Uchida, N; Asao, T; Kuwano, H

    2012-01-01

    Background: A combination of S-1 and cisplatin has been shown to be effective with acceptable safety for the first-line treatment of far-advanced gastric cancer in Japan. This is the first randomised phase II trial to compare S-1+paclitaxel with S-1+cisplatin in this setting. Methods: Patients with unresectable and/or recurrent advanced gastric cancer were randomly assigned to receive one of the two regimens: S-1 (40 mg m−2 twice daily) on days 1–14 plus paclitaxel (60 mg m−2) on days 1, 8, and 15 of a 4-week cycle (S-1+paclitaxel) or S-1 (40 mg m−2 twice daily) on days 1–21 plus cisplatin (60 mg m−2) on day 8 of a 5-week cycle (S-1+cisplatin). The primary end point was the response rate (RR). Secondary end points included progression-free survival (PFS), overall survival (OS), and safety. Results: A total of 83 patients were eligible for safety and efficacy analyses. In the S-1+paclitaxel and S-1+cisplatin groups, RRs (52.3% vs 48.7% P=0.74) and median PFS (9 vs 6 months; P=0.50) were similar. The median OS was similar in the S-1+paclitaxel and S-1+cisplatin groups (16 vs 17 months; P=0.84). The incidence of grade 3 or higher haematological toxicity was 19.0% with S-1+paclitaxel and 19.5% with S-1+cisplatin. The incidence of grade 3 or higher non-haematological toxicity was 14.2% with S-1+paclitaxel and 17.1% with S-1+cisplatin. Conclusion: S-1+paclitaxel was suggested to be a feasible and effective non-platinum-based regimen for chemotherapy in patients with advanced gastric cancer. Our results should be confirmed in multicenter, phase III-controlled clinical trials. PMID:22617130

  1. Building Partnerships Between Research Institutions, University Academic Departments, Local School Districts, and Private Enterprise to Advance K-12 Science Education in Texas

    NASA Astrophysics Data System (ADS)

    Ellins, K. K.; Ganey-Curry, P.; Fennell, T.

    2003-12-01

    The University of Texas at Austin Institute for Geophysics (UTIG) is engaged in six K-12 education and outreach programs, including two NSF-sponsored projects--GK-12: Linking Graduate Fellows with K-12 Students and Teachers and Cataclysms and Catastrophes--Texas Teachers in the Field, Adopt-a-School, Geoscience in the Classroom, and UT's Science and Engineering Apprenticeship Program. The GK-12 Program is central to UTIG's effort and links the six education projects together. While the specific objectives of each project differ, the broad goals of UTIG's education and outreach are to provide high-quality professional development for teachers, develop curriculum resources aligned with state and national education standards, and promote interaction between teachers, scientists, graduate students, and science educators. To achieve these goals, UTIG has forged funded partnerships with scientific colleagues at UT's Bureau of Economic Geology, Marine Science Institute and Department of Geological Sciences; science educators at UT's Charles A. Dana Center and in the Department of Curriculum and Instruction in the College of Education; teachers in six Texas independent school districts; and 4empowerment.com, a private education company that established the "Cyberways and Waterways" Web site to integrate technology and education through an environmentally-based curriculum. These partnerships have allowed UTIG to achieve far more than would have been possible through individual projects alone. Examples include the development of more than 30 inquiry-based activities, hosting workshops and a summer institute, and participation in local science fairs. UTIG has expanded the impact of its education and outreach and achieved broader dissemination of learning activities through 4empowerment's web-based programs, which reach ethnically diverse students in schools across Texas. These partnerships have also helped UTIG and 4empowerment to secure additional funding for other education

  2. National Institute of Neurological Disorders and Stroke (NINDS): Advances in understanding and treating neuropathy, 24–25 October 2006; Bethesda, Maryland

    PubMed Central

    Feldman, Eva L.; Cornblath, David R.; Porter, John; Dworkin, Robert; Scherer, Steven

    2009-01-01

    National Institute of Neurological Disorders and Stroke sponsored a meeting to explore the current status of basic and clinical research in peripheral neurobiology and clinical neuropathy. The goal of the workshop was to identify areas where additional research could lead to the development of new therapeutics in the next 5 years. Participants discussed the current understanding of disease mechanisms of axonal and demyelinating neuropathies, existing techniques in research, disease biomarkers, and assessment of neuropathy. Painful neuropathies were discussed at the basic scientific and clinical levels in relation to new insights into etiology and treatment. The meeting concluded with a discussion on therapeutic development in neuropathy and the need for a unified approach to multicenter trials. Short-term goals of the workshop were to form a working group for neuropathy, the Peripheral Neuropathy Study Group, and to translate new scientific findings into therapies and complete clinical trials. PMID:18346227

  3. 75 FR 28785 - Visiting Committee on Advanced Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Partially Closed Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT), National Institute of Standards...

  4. 76 FR 2662 - Visiting Committee on Advanced Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of partially closed meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT), National Institute of Standards...

  5. 75 FR 60082 - Visiting Committee on Advanced Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT), National Institute of Standards and...

  6. 76 FR 59659 - Visiting Committee on Advanced Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of public meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee), National Institute of Standards...

  7. 76 FR 29195 - Visiting Committee on Advanced Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... National Institute of Standards and Technology Visiting Committee on Advanced Technology AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of Public Meeting. SUMMARY: The Visiting Committee on Advanced Technology (VCAT or Committee), National Institute of Standards...

  8. Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations

    PubMed Central

    Segars, James H.; Parrott, Estella C.; Nagel, Joan D.; Guo, Xiaoxiao Catherine; Gao, Xiaohua; Birnbaum, Linda S.; Pinn, Vivian W.; Dixon, Darlene

    2014-01-01

    BACKGROUND Uterine fibroids are the most common gynecologic tumors in women of reproductive age yet the etiology and pathogenesis of these lesions remain poorly understood. Age, African ancestry, nulliparity and obesity have been identified as predisposing factors for uterine fibroids. Symptomatic tumors can cause excessive uterine bleeding, bladder dysfunction and pelvic pain, as well as associated reproductive disorders such as infertility, miscarriage and other adverse pregnancy outcomes. Currently, there are limited noninvasive therapies for fibroids and no early intervention or prevention strategies are readily available. This review summarizes the advances in basic, applied and translational uterine fibroid research, in addition to current and proposed approaches to clinical management as presented at the ‘Advances in Uterine Leiomyoma Research: 3rd NIH International Congress’. Congress recommendations and a review of the fibroid literature are also reported. METHODS This review is a report of meeting proceedings, the resulting recommendations and a literature review of the subject. RESULTS The research data presented highlights the complexity of uterine fibroids and the convergence of ethnicity, race, genetics, epigenetics and environmental factors, including lifestyle and possible socioeconomic parameters on disease manifestation. The data presented suggest it is likely that the majority of women with uterine fibroids will have normal pregnancy outcomes; however, additional research is warranted. As an alternative to surgery, an effective long-term medical treatment for uterine fibroids should reduce heavy uterine bleeding and fibroid/uterine volume without excessive side effects. This goal has not been achieved and current treatments reduce symptoms only temporarily; however, a multi-disciplined approach to understanding the molecular origins and pathogenesis of uterine fibroids, as presented in this report, makes our quest for identifying novel

  9. Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations.

    PubMed

    Segars, James H; Parrott, Estella C; Nagel, Joan D; Guo, Xiaoxiao Catherine; Gao, Xiaohua; Birnbaum, Linda S; Pinn, Vivian W; Dixon, Darlene

    2014-01-01

    BACKGROUND Uterine fibroids are the most common gynecologic tumors in women of reproductive age yet the etiology and pathogenesis of these lesions remain poorly understood. Age, African ancestry, nulliparity and obesity have been identified as predisposing factors for uterine fibroids. Symptomatic tumors can cause excessive uterine bleeding, bladder dysfunction and pelvic pain, as well as associated reproductive disorders such as infertility, miscarriage and other adverse pregnancy outcomes. Currently, there are limited noninvasive therapies for fibroids and no early intervention or prevention strategies are readily available. This review summarizes the advances in basic, applied and translational uterine fibroid research, in addition to current and proposed approaches to clinical management as presented at the 'Advances in Uterine Leiomyoma Research: 3rd NIH International Congress'. Congress recommendations and a review of the fibroid literature are also reported. METHODS This review is a report of meeting proceedings, the resulting recommendations and a literature review of the subject. RESULTS The research data presented highlights the complexity of uterine fibroids and the convergence of ethnicity, race, genetics, epigenetics and environmental factors, including lifestyle and possible socioeconomic parameters on disease manifestation. The data presented suggest it is likely that the majority of women with uterine fibroids will have normal pregnancy outcomes; however, additional research is warranted. As an alternative to surgery, an effective long-term medical treatment for uterine fibroids should reduce heavy uterine bleeding and fibroid/uterine volume without excessive side effects. This goal has not been achieved and current treatments reduce symptoms only temporarily; however, a multi-disciplined approach to understanding the molecular origins and pathogenesis of uterine fibroids, as presented in this report, makes our quest for identifying novel targets

  10. Effectiveness of capecitabine with or without docetaxel therapy for the treatment of patients with advanced urothelial carcinoma: a single-institution experience

    PubMed Central

    Cao, Ye; Chen, Tanhuan; Yang, Wei; Deng, Yingfei; Han, Hui; Teng, Xiaoyu; Zhou, Fangjian; Shi, Yanxia

    2016-01-01

    Purpose The purpose of this study was to evaluate the effectiveness and toxicity of capecitabine (C) chemotherapy regimen with or without (w/o) docetaxel (D) in patients with advanced urothelial carcinoma (UC). Results Clinical benefit rate were similar in two arms (C arm vs DC arm: 38.9% vs 45.5%, p = 0.411). There were two cases achieved partial response in DC arm. In C arm, the median PFS was 3.0 months (95% CI 2.5–3.5 months) and median OS was 11.3 months (95% CI 8.6–14.1 months). In DC arm, the median PFS was 2.2 months (95% CI 1.7–2.7 months) and median OS was 18 months (95% CI 6.8–29.9 months). Adverse events were mostly acceptable, including myelosuppession, hand-foot syndrome and mucositis. Anemia and leukopenia was found more in the DC arm than in the C arm. Materials and Methods This is a one-center, observational, retrospective study. From April 2009 to March 2015, a total of 29 patients with metastatic UC were included in the study. Survivals, response rates and toxicities were collected retrospectively. Conclusions The result showed the activity and toxicity of C w/o D. As DC treatment did not reveal better outcome, C or D single-agent might be an option in platinum-failed patients with advanced urothelial carcinoma. Further clinical trials are warranted. PMID:27577082

  11. CTOL Transport Technology, 1978. [conferences

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Technology associated with advanced conventional takeoff and landing transport aircraft is discussed. Topics covered include: advanced aerodynamics and active controls; operations and safety; and advanced systems. Emphasis is placed on increased energy efficiency.

  12. The Townes Laser Institute

    NASA Astrophysics Data System (ADS)

    Richardson, Martin

    2009-06-01

    The State of Florida has recently established a new center of excellence in advanced core laser technologies, associated with the College of Optics & Photonics. This center, dedicated in 2007 in tribute to the pioneering work of Charles Townes, whose insight lead to the development of the maser and the laser, will invest in next generation laser technologies for applications to medicine, advanced manufacturing and defense. It joins the cluster of photonics-related centers at UCF, adding a focused national center for the education and training of scientists and engineers in laser technology. This paper describes the mission and objectives of the Townes Institute, the educational and training programs it is creating, its current investments and opportunities, and the future institutional and industrial partnerships and global reach it hopes to create.

  13. Phase 1 Study of Pazopanib in Patients with Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

    PubMed Central

    Shibata, Stephen I; Chung, Vincent; Synold, Timothy; Longmate, Jeffrey; Suttle, A Benjamin; Ottesen, Lone H; Lenz, Heinz-Josef; Kummar, Shivaani; Harvey, R Donald; Hamilton, Anne; O’Neil, Bert; Sarantopoulos, John; LoRusso, Patricia; Rudek, Michelle A; Dowlati, Afshin; Mulkerin, Daniel; Belani, Chandra P.; Gandhi, Leena; Lau, Cecilia; Ivy, S. Percy; Newman, Edward M.

    2013-01-01

    Purpose Pazopanib is a potent, multi-targeted receptor tyrosine kinase inhibitor; however, there is limited information regarding the effects of liver function on pazopanib metabolism and pharmacokinetics (PK). The objective of this study was to establish the maximum tolerated dose (MTD) and PK profile of pazopanib in patients with varying degrees of hepatic dysfunction. Experimental Design Patients with any solid tumors or lymphoma were stratified into four groups based on the degree of hepatic dysfunction according to the National Cancer Institute Organ Dysfunction Working Group (NCI ODWG) criteria. Pazopanib was given orally once a day on a 21-day cycle. A modified 3+3 design was used. Results Ninety eight patients were enrolled. Patients in the mild group tolerated 800 mg per day. The moderate and severe groups tolerated 200 mg per day. Pharmacokinetic data in the mild group were similar to the data in the normal group. Comparison of the median Cmax and AUC(0–24) in the moderate or severe groups at 200 mg per day to the values in the normal and mild groups at 800 mg per day indicated less than dose-proportional systemic exposures in patients with moderate and severe hepatic impairment. This suggests that the lower MTD in the moderate and severe group is not due to a decrease in drug clearance or alteration in the proportion of metabolites. Conclusions In patients with mild liver dysfunction, pazopanib is well tolerated at the FDA-approved dose of 800 mg per day. Patients with moderate and severe liver dysfunction tolerated 200 mg per day. PMID:23653147

  14. Advanced Nodal P3/SP3 Axial Transport Solvers for the MPACT 2D/1D Scheme

    SciTech Connect

    Stimpson, Shane G; Collins, Benjamin S

    2015-01-01

    As part of its initiative to provide multiphysics simulations of nuclear reactor cores, the Consortium for Advanced Simulation of Light Water Reactors (CASL) is developing the Virtual Environment for Reactor Applications Core Simulator (VERA-CS). The MPACT code, which is the primary neutron transport solver of VERA-CS, employs the two-dimensional/one-dimensional (2D/1D) method to solve 3-dimensional neutron transport problems and provide sub-pin-level resolution of the power distribution. While 2D method of characteristics is used to solve for the transport effects within each plane, 1D-nodal methods are used axially. There have been extensive studies of the 2D/1D method with a variety nodal methods, and the P3/SP3 solver has proved to be an effective method of providing higher-fidelity solutions while maintaining a low computational burden.The current implementation in MPACT wraps a one-node nodal expansion method (NEM) kernel for each moment, iterating between them and performing multiple sweeps to resolve flux distributions. However, it has been observed that this approach is more sensitive to convergence problems. This paper documents the theory and application two new nodal P3/SP3 approaches to be used within the 2D/1D method in MPACT. These two approaches aim to provide enhanced stability compared with the pre-existing one-node approach. Results from the HY-NEM-SP3 solver show that the accuracy is consistent with the one-node formulations and provides improved convergence for some problems; but the solver has issues with cases in thin planes. Although the 2N-SENM-SP3 solver is still under development, it is intended to resolve the issues with HY-NEM-SP3 but it will incur some additional computational burden by necessitating an additional 1D-CMFD-P3 solver to generate the second moment cell-averaged scalar flux.

  15. Weekly Low-Dose Docetaxel-Based Chemoradiotherapy for Locally Advanced Oropharyngeal or Hypopharyngeal Carcinoma: A Retrospective, Single-Institution Study

    SciTech Connect

    Fukada, Junichi; Shigematsu, Naoyuki; Takeda, Atsuya; Ohashi, Toshio; Tomita, Toshiki; Shiotani, Akihiro; Kunieda, Etsuo; Kawaguchi, Osamu; Fujii, Masato; Kubo, Atsushi

    2010-02-01

    Purpose: To retrospectively assess the efficacy, toxicity, and prognostic factors of weekly low-dose docetaxel-based chemoradiotherapy for Stage III/IV oropharyngeal or hypopharyngeal carcinoma. Methods and Materials: Between 2001 and 2005, 72 consecutive patients with locally advanced oropharyngeal or hypopharyngeal carcinoma were treated with concurrent chemoradiotherapy (CCR; radiation at 60 Gy plus weekly docetaxel [10 mg/m{sup 2}]). Thirty of these patients also received neoadjuvant chemotherapy (NAC; docetaxel, cisplatin, and 5-fluorouracil) before concurrent chemoradiotherapy. Survival was calculated according to the Kaplan-Meier method. The prognostic factors were evaluated by univariate and multivariate analyses. Results: The median follow-up was 33 months, with overall survival, disease-free survival, and locoregional control rates at 3 years of 59%, 45%, and 52%, respectively. Thirty-six patients (50%) experienced more than one Grade 3 to 4 acute toxicity. Grade 3 mucositis occurred in 32 patients (44%), Grade 4 laryngeal edema in 1 (1%). Grade >=3 severe hematologic toxicity was observed in only 2 patients (3%). Grade 3 dysphagia occurred as a late complication in 2 patients (3%). Multivariate analyses identified age, T stage, hemoglobin level, and completion of weekly docetaxel, but not NAC, as significant factors determining disease-free survival. Conclusions: Docetaxel is an active agent used in both concurrent and sequential chemoradiotherapy regimens. Mucositis was the major acute toxicity, but this was well tolerated in most subjects. Anemia was the most significant prognostic factor determining survival. Further studies are warranted to investigate the optimal protocol for integrating docetaxel into first-line chemoradiotherapy regimens, as well as the potential additive impact of NAC.

  16. Five Years' Experience Treating Locally Advanced Cervical Cancer With Concurrent Chemoradiotherapy and High-Dose-Rate Brachytherapy: Results From a Single Institution

    SciTech Connect

    Parker, Kate; Gallop-Evans, Eve; Hanna, Louise Adams, Malcolm

    2009-05-01

    Purpose: To assess the clinical outcomes after concurrent cisplatin chemotherapy and radiotherapy (RT) followed by high-dose-rate brachytherapy for locally advanced carcinoma of the cervix and perform a multivariate analysis of the prognostic factors. Methods and Materials: The outcomes were analyzed for all women treated between 1999 and 2004 with concurrent cisplatin chemotherapy and RT followed by high-dose-rate brachytherapy. Kaplan-Meier analysis was used for overall survival (OS), local control (LC), and distant control (DC). The Cox proportional hazards model was used to perform multivariate analysis of the prognostic variables. Results: The standard regimen comprised whole pelvic external RT 45 Gy in 25 fractions with concurrent weekly cisplatin 40 mg/m{sup 2}, followed by four high-dose-rate brachytherapy insertions of 6 Gy. Patients with radiologically enlarged para-aortic lymph nodes underwent extended-field RT. Of 92 patients, the OS rate was 72% at 2 years and 55% at 5 years. The LC rate was 76% at 2 years and 67% at 5 years. The DC rate was 68% at 2 years and 48% at 5 years. The most important prognostic factor for OS, LC, and DC was the pretreatment hemoglobin. For OS, the tumor size and the presence of enlarged lymph nodes were also important. For LC, the number of brachytherapy insertions was important; and for DC, the number of chemotherapy treatments was important. Of the patients, 4% experienced late Grade 3 or 4 toxicity. Conclusion: The results of our study have shown that the regimen is effective, with acceptable long-term side effects. In this cohort, the most important prognostic factor was the pretreatment hemoglobin level, a disease-related factor. However, more effective systemic treatments are needed.

  17. Recent advances in transport of water-soluble vitamins in organs of the digestive system: a focus on the colon and the pancreas

    PubMed Central

    2013-01-01

    This review focuses on recent advances in our understanding of the mechanisms and regulation of water-soluble vitamin (WSV) transport in the large intestine and pancreas, two important organs of the digestive system that have only recently received their fair share of attention. WSV, a group of structurally unrelated compounds, are essential for normal cell function and development and, thus, for overall health and survival of the organism. Humans cannot synthesize WSV endogenously; rather, WSV are obtained from exogenous sources via intestinal absorption. The intestine is exposed to two sources of WSV: a dietary source and a bacterial source (i.e., WSV generated by the large intestinal microbiota). Contribution of the latter source to human nutrition/health has been a subject of debate and doubt, mostly based on the absence of specialized systems for efficient uptake of WSV in the large intestine. However, recent studies utilizing a variety of human and animal colon preparations clearly demonstrate that such systems do exist in the large intestine. This has provided strong support for the idea that the microbiota-generated WSV are of nutritional value to the host, and especially to the nutritional needs of the local colonocytes and their health. In the pancreas, WSV are essential for normal metabolic activities of all its cell types and for its exocrine and endocrine functions. Significant progress has also been made in understanding the mechanisms involved in the uptake of WSV and the effect of chronic alcohol exposure on the uptake processes. PMID:23989008

  18. Directory of Transportation Education.

    ERIC Educational Resources Information Center

    Department of Transportation, Washington, DC.

    This directory lists institutions of higher education that offer degree and non-degree programs in various transportation fields and modes, including aviation, highway, urban mass transportation, railroad, water transport, pipeline, intermodal, and environmental and consumer education. The book catalogs courses and degrees offered, names of…

  19. Advanced planetary studies

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Results of planetary advanced studies and planning support are summarized. The scope of analyses includes cost estimation research, planetary mission performance, penetrator advanced studies, Mercury mission transport requirements, definition of super solar electric propulsion/solar sail mission discriminators, and advanced planning activities.

  20. Integration of Advanced Concepts and Vehicles Into the Next Generation Air Transportation System. Volume 1; Introduction, Key Messages, and Vehicle Attributes

    NASA Technical Reports Server (NTRS)

    Zellweger, Andres; Resnick, Herbert; Stevens, Edward; Arkind, Kenneth; Cotton William B.

    2010-01-01

    Raytheon, in partnership with NASA, is leading the way in ensuring that the future air transportation continues to be a key driver of economic growth and stability and that this system provides an environmentally friendly, safe, and effective means of moving people and goods. A Raytheon-led team of industry and academic experts, under NASA contract NNA08BA47C, looked at the potential issues and impact of introducing four new classes of advanced aircraft into the next generation air transportation system -- known as NextGen. The study will help determine where NASA should further invest in research to support the safe introduction of these new air vehicles. Small uncrewed or unmanned aerial systems (SUAS), super heavy transports (SHT) including hybrid wing body versions (HWB), very light jets (VLJ), and supersonic business jets (SSBJ) are the four classes of aircraft that we studied. Understanding each vehicle's business purpose and strategy is critical to assessing the feasibility of new aircraft operations and their impact on NextGen's architecture. The Raytheon team used scenarios created by aviation experts that depict vehicles in year 2025 operations along with scripts or use cases to understand the issues presented by these new types of vehicles. The information was then mapped into the Joint Planning and Development Office's (JPDO s) Enterprise Architecture to show how the vehicles will fit into NextGen's Concept of Operations. The team also identified significant changes to the JPDO's Integrated Work Plan (IWP) to optimize the NextGen vision for these vehicles. Using a proven enterprise architecture approach and the JPDO s Joint Planning Environment (JPE) web site helped make the leap from architecture to planning efficient, manageable and achievable. Very Light Jets flying into busy hub airports -- Supersonic Business Jets needing to climb and descend rapidly to achieve the necessary altitude Super-heavy cargo planes requiring the shortest common flight

  1. Characterization of victims of aggression and transportation accidents treated at the Forensic Medicine and Dentistry Institute - Campina Grande, Paraíba, Brazil - 2010.

    PubMed

    d'Avila, Sergio; Campos, Ana Cristina; Cavalcante, Gigliana Maria Sobral; Silva, Carlos Jose de Paula; da Nóbrega, Lorena Marques; Ferreira, Efigenia Ferreira E

    2015-03-01

    The objective of this cross-sectional census study was to characterize agression and land-based transport accidents in a city in the Northeast of Brazil. Data was analyzed from live victims who were treated at a forensic service (N = 2.379). In the descriptive analysis, the majority of events were represented by aggression (71.6%); which occurred on weekdays (65%), with 35.1% at night. Trauma occurred to the whole body (63.6%) and to soft tissue (74.2%). On the basis of multiple correspondence analysis, two dimensions were formed: the first dimension (internal reliability = 0.654) was formed by the cause of the event, the trauma and the age group and the second dimension (reliability = 0.514), by age group, occupation and civil status. Three groups with distinct profiles were formed for accidents and aggression: young women who suffered aggression, with trauma to the face and soft tissues during the evening and at weekends; adult men who suffered car accidents, in the morning and on work days; and retired elderly widowers, who were run over.

  2. Institutional Censorship

    ERIC Educational Resources Information Center

    Burke, John Gordon; Bowers, H. Paxton

    1970-01-01

    The difficulty an individual who has been denied access to library material faces in obtaining a remedy in the courts dictates that the library profession go on record against all forms of institutional censorship or unreasonable restrictions on use of library materials. (Author/JS)

  3. Institutional betrayal.

    PubMed

    Smith, Carly Parnitzke; Freyd, Jennifer J

    2014-09-01

    A college freshman reports a sexual assault and is met with harassment and insensitive investigative practices leading to her suicide. Former grade school students, now grown, come forward to report childhood abuse perpetrated by clergy, coaches, and teachers--first in trickles and then in waves, exposing multiple perpetrators with decades of unfettered access to victims. Members of the armed services elect to stay quiet about sexual harassment and assault during their military service or risk their careers by speaking up. A Jewish academic struggles to find a name for the systematic destruction of his people in Nazi Germany during the Holocaust. These seemingly disparate experiences have in common trusted and powerful institutions (schools, churches, military, government) acting in ways that visit harm upon those dependent on them for safety and well-being. This is institutional betrayal. The purpose of this article is to describe psychological research that examines the role of institutions in traumatic experiences and psychological distress following these experiences. We demonstrate the ways in which institutional betrayal has been left unseen by both the individuals being betrayed as well as the field of psychology and introduce means by which to identify and address this betrayal.

  4. Institution Morphisms

    NASA Technical Reports Server (NTRS)

    Goguen, Joseph; Rosu, Grigore; Norvig, Peter (Technical Monitor)

    2001-01-01

    Institutions formalize the intuitive notion of logical system, including both syntax and semantics. A surprising number of different notions of morphisim have been suggested for forming categories with institutions as objects, and a surprising variety of names have been proposed for them. One goal of this paper is to suggest a terminology that is both uniform and informative to replace the current rather chaotic nomenclature. Another goal is to investigate the properties and interrelations of these notions. Following brief expositions of indexed categories, twisted relations, and Kan extensions, we demonstrate and then exploit the duality between institution morphisms in the original sense of Goguen and Burstall, and the 'plain maps' of Meseguer, obtaining simple uniform proofs of completeness and cocompleteness for both resulting categories; because of this duality, we prefer the name 'comorphism' over 'plain map.' We next consider 'theoroidal' morphisms and comorphisims, which generalize signatures to theories, finding that the 'maps' of Meseguer are theoroidal comorphisms, while theoroidal morphisms are a new concept. We then introduce 'forward' and 'semi-natural' morphisms, and appendices discuss institutions for hidden algebra, universal algebra, partial equational logic, and a variant of order sorted algebra supporting partiality.

  5. National Space Biomedical Research Institute

    NASA Technical Reports Server (NTRS)

    2003-01-01

    In June 1996, NASA released a Cooperative Agreement Notice (CAN) inviting proposals to establish a National Space Biomedical Research Institute (9-CAN-96-01). This CAN stated that: The Mission of the Institute will be to lead a National effort for accomplishing the integrated, critical path, biomedical research necessary to support the long term human presence, development, and exploration of space and to enhance life on Earth by applying the resultant advances in human knowledge and technology acquired through living and working in space. The Institute will be the focal point of NASA sponsored space biomedical research. This statement has not been amended by NASA and remains the mission of the NSBRI.

  6. Subsonic aerodynamic characteristic of semispan commercial transport model with wing-mounted advanced ducted propeller operating in reverse thrust. [conducted in the Langley 14 by 22 foot subsonic wind tunnel

    NASA Technical Reports Server (NTRS)

    Applin, Zachary T.; Jones, Kenneth M.; Gile, Brenda E.; Quinto, P. Frank

    1994-01-01

    A test was conducted in the Langley 14 by 22 Foot Subsonic Tunnel to determine the effect of the reverse-thrust flow field of a wing-mounted advanced ducted propeller on the aerodynamic characteristics of a semispan subsonic high-lift transport model. The advanced ducted propeller (ADP) model was mounted separately in position alongside the wing so that only the aerodynamic interference of the propeller and nacelle affected the aerodynamic performance of the transport model. Mach numbers ranged from 0.14 to 0.26; corresponding Reynolds numbers ranged from 2.2 to 3.9 x 10(exp 6). The reverse-thrust flow field of the ADP shielded a portion of the wing from the free-stream airflow and reduced both lift and drag. The reduction in lift and drag was a function of ADP rotational speed and free-stream velocity. Test results included ground effects data for the transport model and ADP configuration. The ground plane caused a beneficial increase in drag and an undesirable slight increase in lift. The ADP and transport model performance in ground effect was similar to performance trends observed for out of ground effect. The test results form a comprehensive data set that supports the application of the ADP engine and airplane concept on the next generation of advanced subsonic transports. Before this investigation, the engine application was predicted to have detrimental ground effect characteristics. Ground effect test measurements indicated no critical problems and were the first step in proving the viability of this engine and airplane configuration.

  7. Advanced oxidation protein products decrease the expression of calcium transport channels in small intestinal epithelium via the p44/42 MAPK signaling pathway.

    PubMed

    Wu, Peiqun; Xie, Fang; Xue, Minmin; Xu, Xiaoping; He, Shuying; Lin, Minyi; Bai, Lan

    2015-05-01

    Advanced oxidation protein products (AOPPs), novel protein markers of oxidative damage, accumulate in the plasma of patients with inflammatory bowel disease (IBD). Osteoporosis, which is closely related to the regulation of intestinal calcium transport channels (CTCs), is a prevalent extraintestinal complication of IBD and is associated with oxidative stress. However, the underlying mechanisms are unknown. The present study aimed to verify whether AOPPs inhibit CTCs in the small intestinal epithelium and to identify the underlying mechanisms that may contribute to IBD-associated osteoporosis. Normal Sprague-Dawley rats were treated with AOPP-modified rat serum albumin. The calcium ion level in serum was not significantly altered, while the duodenal expression of CTCs (e.g. transient receptor potential vanilloid [TRPV6], calbindin-D9k [CaBP-D9k], plasma membrane Ca(2+)-ATPase 1 [PMCA1], and Na(+)/Ca(2+) exchanger 1 [NCX1]) were decreased. In contrast, the levels of the related hormones that regulate calcium absorption including parathyroid hormone (PTH), 25-(OH)D₃, and 1,25-(OH)₂D₃ were increased, although the trend toward an increase in PTH levels was not significant. In order to further investigate the effects of AOPP exposure, we also evaluated the expression of CTCs (including the voltage-dependent L-type calcium channel [CaV1.3], TRPV6, CaBP-D9k, PMCA1, and NCX1) in cultured human colorectal adenocarcinoma cells (Caco-2). The expression levels of total CTC protein and mRNA, except for CaV1.3, were significantly down-regulated in a concentration- and time-dependent manner. Moreover, phosphorylation of p44/42 mitogen-activated protein kinase (MAPK) was observed in vivo and in vitro. The p44/42 inhibitor U0126 reversed the down-regulation of CTCs induced by AOPPs in the Caco-2 monolayer. Our results indicate that AOPPs down-regulate the expression of CTCs through p44/42 MAPK signaling mechanisms in the small intestinal epithelium. These data provide new

  8. Joint BioEnergy Institute

    SciTech Connect

    Keasling, Jay; Simmons, Blake; Tartaglino, Virginia; Baidoo, Edward; Kothari, Ankita

    2015-06-15

    The Joint BioEnergy Institute (JBEI) is a U.S. Department of Energy (DOE) Bioenergy Research Center dedicated to developing advanced biofuels—liquid fuels derived from the solar energy stored in plant biomass that can replace gasoline, diesel and jet fuels.

  9. Joint BioEnergy Institute

    ScienceCinema

    Keasling, Jay; Simmons, Blake; Tartaglino, Virginia; Baidoo, Edward; Kothari, Ankita

    2016-07-12

    The Joint BioEnergy Institute (JBEI) is a U.S. Department of Energy (DOE) Bioenergy Research Center dedicated to developing advanced biofuels—liquid fuels derived from the solar energy stored in plant biomass that can replace gasoline, diesel and jet fuels.

  10. Joint Genome Institute's Automation Approach and History

    SciTech Connect

    Roberts, Simon

    2006-07-05

    Department of Energy/Joint Genome Institute (DOE/JGI) collaborates with DOE national laboratories and community users, to advance genome science in support of the DOE missions of clean bio-energy, carbon cycling, and bioremediation.

  11. First observation of a new zonal-flow cycle state in the H-mode transport barrier of the experimental advanced superconducting Tokamak

    SciTech Connect

    Xu, G. S.; Wang, H. Q.; Wan, B. N.; Guo, H. Y.; Zhang, W.; Chang, J. F.; Wang, L.; Chen, R.; Liu, S. C.; Ding, S. Y.; Shao, L. M.; Xiong, H.; Naulin, V.; Diamond, P. H.; Tynan, G. R.; Xu, M.; Yan, N.; Zhao, H. L.

    2012-12-15

    A new turbulence-flow cycle state has been discovered after the formation of a transport barrier in the H-mode plasma edge during a quiescent phase on the EAST superconducting tokamak. Zonal-flow modulation of high-frequency-broadband (0.05-1 MHz) turbulence was observed in the steep-gradient region leading to intermittent transport events across the edge transport barrier. Good confinement (H{sub 98y,2} {approx} 1) has been achieved in this state, even with input heating power near the L-H transition threshold. A novel model based on predator-prey interaction between turbulence and zonal flows reproduced this state well.

  12. Advanced Civilian Aeronautical Concepts

    NASA Technical Reports Server (NTRS)

    Bushnell, Dennis M.

    1996-01-01

    Paper discusses alternatives to currently deployed systems which could provide revolutionary improvements in metrics applicable to civilian aeronautics. Specific missions addressed include subsonic transports, supersonic transports and personal aircraft. These alternative systems and concepts are enabled by recent and envisaged advancements in electronics, communications, computing and Designer Fluid Mechanics in conjunction with a design approach employing extensive synergistic interactions between propulsion, aerodynamics and structures.

  13. Institutional plan. FY 1998--2003

    SciTech Connect

    1997-07-01

    This Institutional Plan for Argonne National Laboratory contains central elements of Argonne`s strategic plan. Chapter II of this document discusses the Laboratory`s mission and core competencies. Chapter III presents the Science and Technology Strategic Plan, which summarizes key features of the external environment, presents Argonne`s vision, and describes how the Laboratory`s strategic goals and objectives map onto and support DOE`s four business lines. The balance of the chapter comprises the science and technology area plans, organized by the four DOE business lines. Chapter IV describes the Laboratory`s ten major initiatives, which cover a broad spectrum of science and technology. Our proposal for an Exotic Beam Facility aims at, among other things, increased understanding of the processes of nuclear synthesis during and shortly after the Big Bang. Our Advanced Transportation Technology initiative involves working with US industry to develop cost-effective technologies to improve the fuel efficiency and reduce the emissions of transportation systems. The Laboratory`s plans for the future depend significantly on the success of its major initiatives. Chapter V presents our Operations and Infrastructure Strategic Plan. The main body of the chapter comprises strategic plans for human resources; environmental protection, safety, and health; site and facilities; and information management. The chapter concludes with a discussion of the business and management practices that Argonne is adopting to improve the quality and cost-effectiveness of its operations. The structure and content of this document depart from those of the Institutional Plan in previous years. Emphasis here is on directions for the future; coverage of ongoing activities is less detailed. We hope that this streamlined plan is more direct and accessible.

  14. Program plan and summary, remote fluvial experimental (REFLEX) series: Research experiments using advanced remote sensing technologies with emphasis on hydrologic transport, and hydrologic-ecologic interactions

    SciTech Connect

    Wobber, F.J.

    1986-10-01

    This document describes research designed to evaluate advanced remote sensing technologies for environmental research. A series of Remote Fluvial Experiments (REFLEX) - stressing new applications of remote sensing systems and use of advanced digital analysis methods - are described. Program strategy, experiments, research areas, and future initiatives are summarized. The goals of REFLEX are: (1) to apply new and developing aerial and satellite remote sensing technologies - including both advanced sensor systems and digital/optical processing - for interdisciplinary scientific experiments in hydrology and to hydrologic/ecologic interactions; (2) to develop new concepts for processing and analyzing remote sensing data for general scientific application; and (3) to demonstrate innovative analytical technologies that advance the state of the art in applying information from remote sensing systems, for example, supercomputer processing and analysis.

  15. Scientific and Information Activities of Institute's Libraries.

    ERIC Educational Resources Information Center

    Portnov, N.

    An analysis of the information service of the Leningrad Institute of Railway Transportation Engineer's libraries led to the following conclusions: Optimal information service for all basic needs of the users in an institute can be ensured by the combined efforts of the libraries and their information services. University libraries should supply…

  16. Expanded Concepts of the School Library Media Center; Narrative Evaluation Report on the Institute for Advanced Study for Librarians...University of Washington...July 6 to July 17, 1970.

    ERIC Educational Resources Information Center

    Washington Univ., Seattle. School of Librarianship.

    The purpose of the institute was to update school librarians in elementary and secondary schools and enable them to gain competency in the new media. The objectives of the institute were to assist the school librarian in the selection, processing and utilization of nonbook media, to learn simple techniques in production of materials, and to…

  17. Workshop on Atmospheric Transport on Mars

    NASA Technical Reports Server (NTRS)

    Barnes, J. R. (Editor); Haberle, R. M. (Editor)

    1993-01-01

    On June 28-30, 1993, the Workshop on Atmospheric Transport on Mars was held in Corvallis, Oregon. The workshop was organized under the auspices of the MSATT (Mars Surface and Atmosphere Through Time) Program of NASA, and was jointly sponsored by the Lunar and Planetary Institute, Oregon State University, and the Oregon Space Grant Consortium. More than 50 scientists attended the workshop, which was the first such meeting to focus upon circulation processes in the Mars atmosphere. The timing of the workshop placed it almost on the eve of the arrival of Mars Observer at Mars, so that the presented papers gave a picture of the 'state of the art' in Mars atmospheric science just prior to the expected arrival of new data. The workshop highlighted a host of recent advances in atmospheric modeling and analysis - advances that will be relevant to any future observations.

  18. Intermediate/Advanced Research Design and Statistics

    NASA Technical Reports Server (NTRS)

    Ploutz-Snyder, Robert

    2009-01-01

    The purpose of this module is To provide Institutional Researchers (IRs) with an understanding of the principles of advanced research design and the intermediate/advanced statistical procedures consistent with such designs

  19. Advanced lubrication systems and materials. Final report

    SciTech Connect

    Hsu, S.

    1998-05-07

    This report described the work conducted at the National Institute of Standards and Technology under an interagency agreement signed in September 1992 between DOE and NIST for 5 years. The interagency agreement envisions continual funding from DOE to support the development of fuel efficient, low emission engine technologies in terms of lubrication, friction, and wear control encountered in the development of advanced transportation technologies. However, in 1994, the DOE office of transportation technologies was reorganized and the tribology program was dissolved. The work at NIST therefore continued at a low level without further funding from DOE. The work continued to support transportation technologies in the development of fuel efficient, low emission engine development. Under this program, significant progress has been made in advancing the state of the art of lubrication technology for advanced engine research and development. Some of the highlights are: (1) developed an advanced high temperature liquid lubricant capable of sustaining high temperatures in a prototype heat engine; (2) developed a novel liquid lubricant which potentially could lower the emission of heavy duty diesel engines; (3) developed lubricant chemistries for ceramics used in the heat engines; (4) developed application maps for ceramic lubricant chemistry combinations for design purpose; and (5) developed novel test methods to screen lubricant chemistries for automotive air-conditioning compressors lubricated by R-134a (Freon substitute). Most of these findings have been reported to the DOE program office through Argonne National Laboratory who manages the overall program. A list of those reports and a copy of the report submitted to the Argonne National Laboratory is attached in Appendix A. Additional reports have also been submitted separately to DOE program managers. These are attached in Appendix B.

  20. Cyclotron Institute Upgrade Project

    SciTech Connect

    Clark, Henry; Yennello, Sherry; Tribble, Robert

    2014-08-26

    The Cyclotron Institute at Texas A&M University has upgraded its accelerator facilities to extend research capabilities with both stable and radioactive beams. The upgrade is divided into three major tasks: (1) re-commission the K-150 (88”) cyclotron, couple it to existing beam lines to provide intense stable beams into the K-500 experimental areas and use it as a driver to produce radioactive beams; (2) develop light ion and heavy ion guides for stopping radioactive ions created with the K-150 beams; and (3) transport 1+ ions from the ion guides into a charge-breeding electron-cyclotron-resonance ion source (CB-ECR) to produce highly-charged radioactive ions for acceleration in the K-500 cyclotron. When completed, the upgraded facility will provide high-quality re-accelerated secondary beams in a unique energy range in the world.