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Sample records for advancing front method

  1. Unstructured viscous grid generation by advancing-front method

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar

    1993-01-01

    A new method of generating unstructured triangular/tetrahedral grids with high-aspect-ratio cells is proposed. The method is based on new grid-marching strategy referred to as 'advancing-layers' for construction of highly stretched cells in the boundary layer and the conventional advancing-front technique for generation of regular, equilateral cells in the inviscid-flow region. Unlike the existing semi-structured viscous grid generation techniques, the new procedure relies on a totally unstructured advancing-front grid strategy resulting in a substantially enhanced grid flexibility and efficiency. The method is conceptually simple but powerful, capable of producing high quality viscous grids for complex configurations with ease. A number of two-dimensional, triangular grids are presented to demonstrate the methodology. The basic elements of the method, however, have been primarily designed with three-dimensional problems in mind, making it extendible for tetrahedral, viscous grid generation.

  2. General advancing front packing algorithm for the discrete element method

    NASA Astrophysics Data System (ADS)

    Morfa, Carlos A. Recarey; Pérez Morales, Irvin Pablo; de Farias, Márcio Muniz; de Navarra, Eugenio Oñate Ibañez; Valera, Roberto Roselló; Casañas, Harold Díaz-Guzmán

    2016-11-01

    A generic formulation of a new method for packing particles is presented. It is based on a constructive advancing front method, and uses Monte Carlo techniques for the generation of particle dimensions. The method can be used to obtain virtual dense packings of particles with several geometrical shapes. It employs continuous, discrete, and empirical statistical distributions in order to generate the dimensions of particles. The packing algorithm is very flexible and allows alternatives for: 1—the direction of the advancing front (inwards or outwards), 2—the selection of the local advancing front, 3—the method for placing a mobile particle in contact with others, and 4—the overlap checks. The algorithm also allows obtaining highly porous media when it is slightly modified. The use of the algorithm to generate real particle packings from grain size distribution curves, in order to carry out engineering applications, is illustrated. Finally, basic applications of the algorithm, which prove its effectiveness in the generation of a large number of particles, are carried out.

  3. Investigation of advancing front method for generating unstructured grid

    NASA Astrophysics Data System (ADS)

    Thomas, A. M.; Tiwari, S. N.

    1992-06-01

    The advancing front technique is used to generate an unstructured grid about simple aerodynamic geometries. Unstructured grids are generated using VGRID2D and VGRID3D software. Specific problems considered are a NACA 0012 airfoil, a bi-plane consisting of two NACA 0012 airfoil, a four element airfoil in its landing configuration, and an ONERA M6 wing. Inviscid time dependent solutions are computed on these geometries using USM3D and the results are compared with standard test results obtained by other investigators. A grid convergence study is conducted for the NACA 0012 airfoil and compared with a structured grid. A structured grid is generated using GRIDGEN software and inviscid solutions computed using CFL3D flow solver. The results obtained by unstructured grid for NACA 0012 airfoil showed an asymmetric distribution of flow quantities, and a fine distribution of grid was required to remove this asymmetry. On the other hand, the structured grid predicted a very symmetric distribution, but when the total number of points were compared to obtain the same results it was seen that structured grid required more grid points.

  4. Investigation of advancing front method for generating unstructured grid

    NASA Technical Reports Server (NTRS)

    Thomas, A. M.; Tiwari, S. N.

    1992-01-01

    The advancing front technique is used to generate an unstructured grid about simple aerodynamic geometries. Unstructured grids are generated using VGRID2D and VGRID3D software. Specific problems considered are a NACA 0012 airfoil, a bi-plane consisting of two NACA 0012 airfoil, a four element airfoil in its landing configuration, and an ONERA M6 wing. Inviscid time dependent solutions are computed on these geometries using USM3D and the results are compared with standard test results obtained by other investigators. A grid convergence study is conducted for the NACA 0012 airfoil and compared with a structured grid. A structured grid is generated using GRIDGEN software and inviscid solutions computed using CFL3D flow solver. The results obtained by unstructured grid for NACA 0012 airfoil showed an asymmetric distribution of flow quantities, and a fine distribution of grid was required to remove this asymmetry. On the other hand, the structured grid predicted a very symmetric distribution, but when the total number of points were compared to obtain the same results it was seen that structured grid required more grid points.

  5. Structured background grids for generation of unstructured grids by advancing front method

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar

    1991-01-01

    A new method of background grid construction is introduced for generation of unstructured tetrahedral grids using the advancing-front technique. Unlike the conventional triangular/tetrahedral background grids which are difficult to construct and usually inadequate in performance, the new method exploits the simplicity of uniform Cartesian meshes and provides grids of better quality. The approach is analogous to solving a steady-state heat conduction problem with discrete heat sources. The spacing parameters of grid points are distributed over the nodes of a Cartesian background grid by interpolating from a few prescribed sources and solving a Poisson equation. To increase the control over the grid point distribution, a directional clustering approach is used. The new method is convenient to use and provides better grid quality and flexibility. Sample results are presented to demonstrate the power of the method.

  6. Generation of three-dimensional unstructured grids by the advancing-front method

    NASA Technical Reports Server (NTRS)

    Lohner, Rainald; Parikh, Paresh

    1988-01-01

    The generation of three-dimensional unstructured grids using the advancing-front technique is described. While this generation technique has been shown to be effective for the generation of unstructured grids in two dimensions, its extension to three-dimensional regions required the development of surface definition software and sophisticated data structures to avoid excessive CPU-time overheads for the search operations involved. After obtaining an initial triangulation of the surfaces, tetrahedrons are generated by successively deleting faces from the generation front. Details of the mesh generation algorithm are given, together with examples and timings.

  7. Pressure transient method for front tracking

    SciTech Connect

    Benson, S.M.; Bodvarsson, G.S.

    1983-08-01

    A pressure transient technique for tracking the advance of cold water fronts during water flooding and goethermal injection operations has been developed. The technique is based on the concept that the steady state pressure buildup in the reservoir region inside the front can be calculated by a fluid skin factor. By analyzing successive pressure falloff tests, the advance of the front in the reservoir can be monitored. The validity of the methods is demonstrated by application to three numerically simulated data sets, a nonisothermal step-rate injection test, a series of pressure falloffs in a multilayered reservoir, and a series of pressure falloff tests in a water flooded oil reservoir.

  8. Translational genetics: advancing fronts for craniofacial health.

    PubMed

    D'Souza, R N; Dunnwald, M; Dunnvald, M; Frazier-Bowers, S; Polverini, P J; Wright, J T; de Rouen, T; Vieira, A R

    2013-12-01

    Scientific opportunities have never been better than today! The completion of the Human Genome project has sparked hope and optimism that cures for debilitating conditions can be achieved and tailored to individuals and communities. The availability of reference genome sequences and genetic variations as well as more precise correlations between genotype and phenotype have facilitated the progress made in finding solutions to clinical problems. While certain craniofacial and oral diseases previously deemed too difficult to tackle have benefited from basic science and technological advances over the past decade, there remains a critical need to translate the fruits of several decades' worth of basic and clinical research into tangible therapies that can benefit patients. The fifth Annual Fall Focused Symposium, "Translational Genetics - Advancing Fronts for Craniofacial Health", was created by the American Association for Dental Research (AADR) to foster its mission to advance interdisciplinary research that is directed toward improving oral health. The symposium showcased progress made in identifying molecular targets that are potential therapeutics for common and rare dental diseases and craniofacial disorders. Speakers focused on translational and clinical applications of their research and, where applicable, on strategies for new technologies and therapeutics. The critical needs to transfer new knowledge to the classroom and for further investment in the field were also emphasized. The symposium underscored the importance of basic research, chairside clinical observations, and population-based studies in driving the new translational connections needed for the development of cures for the most common and devastating diseases involving the craniofacial complex.

  9. An advancing front Delaunay triangulation algorithm designed for robustness

    NASA Technical Reports Server (NTRS)

    Mavriplis, D. J.

    1992-01-01

    A new algorithm is described for generating an unstructured mesh about an arbitrary two-dimensional configuration. Mesh points are generated automatically by the algorithm in a manner which ensures a smooth variation of elements, and the resulting triangulation constitutes the Delaunay triangulation of these points. The algorithm combines the mathematical elegance and efficiency of Delaunay triangulation algorithms with the desirable point placement features, boundary integrity, and robustness traditionally associated with advancing-front-type mesh generation strategies. The method offers increased robustness over previous algorithms in that it cannot fail regardless of the initial boundary point distribution and the prescribed cell size distribution throughout the flow-field.

  10. Nonperturbative light-front Hamiltonian methods

    NASA Astrophysics Data System (ADS)

    Hiller, J. R.

    2016-09-01

    We examine the current state-of-the-art in nonperturbative calculations done with Hamiltonians constructed in light-front quantization of various field theories. The language of light-front quantization is introduced, and important (numerical) techniques, such as Pauli-Villars regularization, discrete light-cone quantization, basis light-front quantization, the light-front coupled-cluster method, the renormalization group procedure for effective particles, sector-dependent renormalization, and the Lanczos diagonalization method, are surveyed. Specific applications are discussed for quenched scalar Yukawa theory, ϕ4 theory, ordinary Yukawa theory, supersymmetric Yang-Mills theory, quantum electrodynamics, and quantum chromodynamics. The content should serve as an introduction to these methods for anyone interested in doing such calculations and as a rallying point for those who wish to solve quantum chromodynamics in terms of wave functions rather than random samplings of Euclidean field configurations.

  11. Three-dimensional hybrid grid generation using advancing front techniques

    NASA Technical Reports Server (NTRS)

    Steinbrenner, John P.; Noack, Ralph W.

    1995-01-01

    A new 3-dimensional hybrid grid generation technique has been developed, based on ideas of advancing fronts for both structured and unstructured grids. In this approach, structured grids are first generate independently around individual components of the geometry. Fronts are initialized on these structure grids, and advanced outward so that new cells are extracted directly from the structured grids. Employing typical advancing front techniques, cells are rejected if they intersect the existing front or fail other criteria When no more viable structured cells exist further cells are advanced in an unstructured manner to close off the overall domain, resulting in a grid of 'hybrid' form. There are two primary advantages to the hybrid formulation. First, generating blocks with limited regard to topology eliminates the bottleneck encountered when a multiple block system is used to fully encapsulate a domain. Individual blocks may be generated free of external constraints, which will significantly reduce the generation time. Secondly, grid points near the body (presumably with high aspect ratio) will still maintain a structured (non-triangular or tetrahedral) character, thereby maximizing grid quality and solution accuracy near the surface.

  12. Front lighted shadowgraphic method and apparatus

    DOEpatents

    Stone, William J.

    1985-02-26

    High contrast silhouette images of a substantially opaque object are obtained using front illumination techniques. The object is frontally illuminated by light of a first polarization. A frontal surface of the object reflects the incident light to an observation station. The polarization of incident light bypassing the object and incident on a background is changed. The background light is reflected to the observation station, and the intensity of one of the two, differently polarized, reflected images is substantially reduced with respect to the other. Apparatus for carrying out the method includes a first polarizer for polarizing frontally incident illuminating light, a second polarizer behind the object and a reflective surface behind the second polarizer. A polarization analyzer, located in front of the object, is used to extinguish one of the two reflected images. Apparatus for carrying out the invention in instruments having a polarized light source and a polarization analyzer includes a combination of a polarizing material, for contacting a rear surface of the object, and a reflective surface provided adjacent the rear surface of the polarizing material. The combination is applied to the rear surface of the object. Back-surface mirrors of pleochroic substrates applied to thin film physical vapor deposited electronic circuit elements enable front lighted shadowgraphic imaging of the elements.

  13. Front lighted optical tooling method and apparatus

    DOEpatents

    Stone, William J.

    1985-06-18

    An optical tooling method and apparatus uses a front lighted shadowgraphic technique to enhance visual contrast of reflected light. The apparatus includes an optical assembly including a fiducial mark, such as cross hairs, reflecting polarized light with a first polarization, a polarizing element backing the fiducial mark and a reflective surface backing the polarizing element for reflecting polarized light bypassing the fiducial mark and traveling through the polarizing element. The light reflected by the reflecting surface is directed through a second pass of the polarizing element toward the frontal direction with a polarization differing from the polarization of the light reflected by the fiducial mark. When used as a tooling target, the optical assembly may be mounted directly to a reference surface or may be secured in a mounting, such as a magnetic mounting. The optical assembly may also be mounted in a plane defining structure and used as a spherometer in conjunction with an optical depth measuring instrument. A method of measuring a radius of curvature of an unknown surface includes positioning the spherometer on a surface between the surface and a depth measuring optical instrument. As the spherometer is frontally illuminated, the distance from the depth measuring instrument to the fiducial mark and the underlying surface are alternately measured and the difference in these measurements is used as the sagittal height to calculate a radius of curvature.

  14. Unconstrained plastering : all-hexahedral mesh generation via advancing front geometry decomposition (2004-2008).

    SciTech Connect

    Blacker, Teddy Dean; Staten, Matthew L.; Kerr, Robert A.; Owen, Steven James

    2010-03-01

    The generation of all-hexahedral finite element meshes has been an area of ongoing research for the past two decades and remains an open problem. Unconstrained plastering is a new method for generating all-hexahedral finite element meshes on arbitrary volumetric geometries. Starting from an unmeshed volume boundary, unconstrained plastering generates the interior mesh topology without the constraints of a pre-defined boundary mesh. Using advancing fronts, unconstrained plastering forms partially defined hexahedral dual sheets by decomposing the geometry into simple shapes, each of which can be meshed with simple meshing primitives. By breaking from the tradition of previous advancing-front algorithms, which start from pre-meshed boundary surfaces, unconstrained plastering demonstrates that for the tested geometries, high quality, boundary aligned, orientation insensitive, all-hexahedral meshes can be generated automatically without pre-meshing the boundary. Examples are given for meshes from both solid mechanics and geotechnical applications.

  15. Advanced integrated safeguards using front-end-triggering devices

    SciTech Connect

    Howell, J.A.; Whitty, W.J.

    1995-12-01

    This report addresses potential uses of front-end-triggering devices for enhanced safeguards. Such systems incorporate video surveillance as well as radiation and other sensors. Also covered in the report are integration issues and analysis techniques.

  16. Advanced Oxy-Fuel-Fired Front-End System

    SciTech Connect

    2004-03-01

    Oxy-gas-fired front-end technology promises significantly reduced energy usage. The glass industry is widely recognized as one of the most energy-intensive manufacturing industries in the United States.

  17. Pulse front adaptive optics: a new method for control of ultrashort laser pulses.

    PubMed

    Sun, Bangshan; Salter, Patrick S; Booth, Martin J

    2015-07-27

    Ultrafast lasers enable a wide range of physics research and the manipulation of short pulses is a critical part of the ultrafast tool kit. Current methods of laser pulse shaping are usually considered separately in either the spatial or the temporal domain, but laser pulses are complex entities existing in four dimensions, so full freedom of manipulation requires advanced forms of spatiotemporal control. We demonstrate through a combination of adaptable diffractive and reflective optical elements - a liquid crystal spatial light modulator (SLM) and a deformable mirror (DM) - decoupled spatial control over the pulse front (temporal group delay) and phase front of an ultra-short pulse was enabled. Pulse front modulation was confirmed through autocorrelation measurements. This new adaptive optics technique, for the first time enabling in principle arbitrary shaping of the pulse front, promises to offer a further level of control for ultrafast lasers.

  18. Methods for enhancing mapping of thermal fronts in oil recovery

    DOEpatents

    Lee, David O.; Montoya, Paul C.; Wayland, Jr., James R.

    1987-01-01

    A method for enhancing the resistivity contrasts of a thermal front in an oil recovery production field as measured by the CSAMT technique is disclosed. This method includes the steps of: (a) preparing a CSAMT-determined topological resistivity map of the production field; (b) introducing a solution of a dopant material into the production field at a concentration effective to alter the resistivity associated with the thermal front; said dopant material having a high cation exchange capacity which might be selected from the group consisting of montmorillonite, illite, and chlorite clays; said material being soluble in the connate water of the production field; (c) preparing a CSAMT-determined topological resistivity map of the production field while said dopant material is moving therethrough; and (d) mathematically comparing the maps from step (a) and step (c) to determine the location of the thermal front. This method is effective with the steam flood, fire flood and water flood techniques.

  19. Methods for enhancing mapping of thermal fronts in oil recovery

    DOEpatents

    Lee, D.O.; Montoya, P.C.; Wayland, J.R. Jr.

    1984-03-30

    A method for enhancing the resistivity contrasts of a thermal front in an oil recovery production field as measured by the controlled source audio frequency magnetotelluric (CSAMT) technique is disclosed. This method includes the steps of: (1) preparing a CSAMT-determined topological resistivity map of the production field; (2) introducing a solution of a dopant material into the production field at a concentration effective to alter the resistivity associated with the thermal front; said dopant material having a high cation exchange capacity which might be selected from the group consisting of montmorillonite, illite, and chlorite clays; said material being soluble in the conate water of the production field; (3) preparing a CSAMT-determined topological resistivity map of the production field while said dopant material is moving therethrough; and (4) mathematically comparing the maps from step (1) and step (3) to determine the location of the thermal front. This method is effective with the steam flood, fire flood and water flood techniques.

  20. Advanced Usability Evaluation Methods

    DTIC Science & Technology

    2007-04-01

    tracking in usability evaluation : A practitioner’s guide. In J. Hyönä, R. Radach, & H. Deubel. (Eds.), The mind’s eye: Cognitive and applied...Advanced Usability Evaluation Methods Terence S. Andre, Lt Col, USAF Margaret Schurig, Human Factors Design Specialist, The Boeing Co...TITLE AND SUBTITLE Advanced Usability Evaluation Methods 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

  1. Advancing-layers method for generation of unstructured viscous grids

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar

    1993-01-01

    A novel approach for generating highly stretched grids which is based on a modified advancing-front technique and benefits from the generality, flexibility, and grid quality of the conventional advancing-front-based Euler grid generators is presented. The method is self-sufficient for the insertion of grid points in the boundary layer and beyond. Since it is based on a totally unstructured grid strategy, the method alleviates the difficulties stemming from the structural limitations of the prismatic techniques.

  2. Conceptual Design of Front Ends for the Advanced Photon Source Multi-bend Achromats Upgrade

    SciTech Connect

    Jaski, Y.; Westferro, F.; Lee, S. H.; Yang, B.; Abliz, M.; Ramanathan, M.

    2016-07-27

    The proposed Advanced Photon Source (APS) upgrade from a double-bend achromats (DBA) to multi-bend achromats (MBA) lattice with ring energy change from 7 GeV to 6 GeV and beam current from 100 mA to 200 mA poses new challenges for front ends. All front ends must be upgraded to fulfill the following requirements: 1) handle the high heat load from two insertion devices in either inline or canted configuration, 2) include a clearing magnet in the front end to deflect and dump any electrons in case the electrons escape from the storage ring during swap-out injection with the safety shutters open, 3) incorporate the next generation x-ray beam position monitors (XBPMs) into the front end to meet the new stringent beam stability requirements. This paper presents the evaluation of the existing APS front ends and standardizes the insertion device (ID) front ends into two types: one for the single beam and one for the canted beams. The conceptual design of high heat load front end (HHLFE) and canted undulator front end (CUFE) for APS MBA upgrade is presented.

  3. CHARACTERIZATION OF THE ADVANCED RADIOGRAPHIC CAPABILITY FRONT END ON NIF

    SciTech Connect

    Haefner, C; Heebner, J; Dawson, J; Fochs, S; Shverdin, M; Crane, J K; Kanz, V K; Halpin, J; Phan, H; Sigurdsson, R; Brewer, W; Britten, J; Brunton, G; Clark, W; Messerly, M J; Nissen, J D; Nguyen, H; Shaw, B; Hackel, R; Hermann, M; Tietbohl, G; Siders, C W; Barty, C J

    2009-07-15

    We have characterized the Advanced Radiographic Capability injection laser system and demonstrated that it meets performance requirements for upcoming National Ignition Facility fusion experiments. Pulse compression was achieved with a scaled down replica of the meter-scale grating ARC compressor and sub-ps pulse duration was demonstrated at the Joule-level.

  4. A Subgrid-Scale Parameterization for Calving-Front Advance and Retreat

    NASA Astrophysics Data System (ADS)

    Albrecht, Torsten

    2010-05-01

    Floating ice shelves fringing most of Antarctica play a key for the flow of ice into the ocean and thereby for global sea level rise. Calving processes at the ice front are highly complex and are often neglected in numerical ice sheet models. Observed accelerated ice discharge after abrupt ice shelf retreat proofs that this is not a viable approach. In order to be able to take ice shelf dynamics into account we have implemented a number of processes into the Potsdam Parallel Ice Sheet Model (PISM-PIK). We present a newly developed subgrid-scale parameterization for calving-front advance and retreat which allows the introduction of stress boundary conditions on the ice-ocean front and thereby a proper computation of the stress and strain field along the calving front. With these improvements we compare different calving rate approaches for different realistic ice shelf geometries (Albrecht et al., J Glac., in prep.).

  5. A nonperturbative light-front coupled-cluster method

    NASA Astrophysics Data System (ADS)

    Hiller, J. R.

    2012-10-01

    The nonperturbative Hamiltonian eigenvalue problem for bound states of a quantum field theory is formulated in terms of Dirac's light-front coordinates and then approximated by the exponential-operator technique of the many-body coupled-cluster method. This approximation eliminates any need for the usual approximation of Fock-space truncation. Instead, the exponentiated operator is truncated, and the terms retained are determined by a set of nonlinear integral equations. These equations are solved simultaneously with an effective eigenvalue problem in the valence sector, where the number of constituents is small. Matrix elements can be calculated, with extensions of techniques from standard coupled-cluster theory, to obtain form factors and other observables.

  6. The advance of an advantageous allele: Nucleation, front propagation, and seasonal effects

    NASA Astrophysics Data System (ADS)

    O'Malley, Lauren

    Both community ecology and conservation biology seek further understanding of factors governing the advance of an invasive species. I model biological invasion as a two-species, individual-based stochastic process on a two-dimensional landscape. The ecologically superior invader and a resident species compete for space preemptively. The invasive species can occur through random, rare mutations of the resident species, or as a repeated introduction into the environment. To understand how individual-level processes may govern population patterns, I invoke the physical theory for nucleation of spatial systems. Nucleation theory discriminates between single-cluster and multi-cluster dynamics. A sufficiently low mutation or introduction rate, or a sufficiently small environment generates single-cluster dynamics, an inherently stochastic process. An increased mutation or introduction rate, or larger system size generates multi-cluster invasion, where spatial averaging produces nearly deterministic global dynamics. For this process, an analytical approximation from nucleation theory, called Avrami's Law, describes the time-dependent behavior for the densities with remarkable accuracy. Once invasive clusters grow large enough, observations of the invasive advance occur only through a small "window" of space, where we can approximate the advance as that of a linear propagating front. One can then employ the concept of a "roughened" front to quantify effects of discreteness and stochasticity on invasion, and thus study roughening of the front using the framework of non-equilibrium interface growth. The analysis, which includes calculating the scaling (roughness and dynamic) exponents, corrections to the asymptotic front velocity, and the probability distribution of both the surface roughness and the front runner's relative position, indicates that initially flat, linear invading fronts exhibit Kardar-Parisi-Zhang (KPZ) roughening in one transverse dimension. I also study the

  7. The Transition Zone Chlorophyll Front updated: Advances from a decade of research

    NASA Astrophysics Data System (ADS)

    Polovina, Jeffrey J.; Howell, Evan A.; Kobayashi, Donald R.; Seki, Michael P.

    2017-01-01

    The dynamic ocean feature called the Transition Zone Chlorophyll Front (TZCF) was first described fifteen years ago based on an empirical association between the apparent habitat of loggerhead sea turtles and albacore tuna linked to a basin-wide chlorophyll front observed with remotely sensed ocean color data. Subsequent research has provided considerable evidence that the TZCF is an indicator for a dynamic ocean feature with important physical and biological characteristics. New insights into the seasonal dynamics of the TZCF suggest that in the summer it is located at the southern boundary of the subarctic gyre while its position in the winter and spring is defined by the extent of the southward transport of surface nutrients. While the TZCF is defined as the dynamic boundary between low and high surface chlorophyll, it appears to be a boundary between subtropical and subarctic phytoplankton communities. Furthermore, the TZCF is also characterized as supporting enhanced phytoplankton net community production throughout its seasonal migration. Lastly, the TZCF is important to the growth rate of neon flying squid and to the survival of monk seal pups in the northern atolls of the Hawaiian Archipelago. This paper reviews these and other findings that advance our current understanding of the physics and biology of the TZCF from research over the past decade.

  8. Mathematical Methods in Wave Propagation: Part 2--Non-Linear Wave Front Analysis

    ERIC Educational Resources Information Center

    Jeffrey, Alan

    1971-01-01

    The paper presents applications and methods of analysis for non-linear hyperbolic partial differential equations. The paper is concluded by an account of wave front analysis as applied to the piston problem of gas dynamics. (JG)

  9. Advances in Adaptive Control Methods

    NASA Technical Reports Server (NTRS)

    Nguyen, Nhan

    2009-01-01

    This poster presentation describes recent advances in adaptive control technology developed by NASA. Optimal Control Modification is a novel adaptive law that can improve performance and robustness of adaptive control systems. A new technique has been developed to provide an analytical method for computing time delay stability margin for adaptive control systems.

  10. Editorial: biotech methods and advances.

    PubMed

    Jungbauer, Alois

    2013-01-01

    This annual Methods and Advances Special Issue of Biotechnology Journal contains a selection of cutting-edge research and review articles with a particular emphasis on vertical process understanding – read more in this editorial by Prof. Alois Jungbauer, BTJ co-Editor-in-Chief.

  11. Front-End Analysis Methods for the Noncommissioned Officer Education System

    DTIC Science & Technology

    2013-02-01

    Research Report 1964 Front-End Analysis Methods for the Noncommissioned Officer Education System Marisa L. Miller U.S...2012 4. TITLE AND SUBTITLE Front-End Analysis Methods for the Noncommissioned Officer Education System 5a. CONTRACT OR GRANT NUMBER W5J9CQ-11-D...The Noncommissioned Officer Education System plays a crucial role in Soldier development by providing both institutional training and structured-self

  12. Development of a zero-method interferometer by means of dynamic generation of reference wave front

    NASA Astrophysics Data System (ADS)

    Hanayama, Ryohei; Ishii, Katsuhiro

    2013-04-01

    In this report, we propose a zero-method interferometer by means of dynamic generation of reference wave front using liquid crystal type spatial light modulator (LCoS-SLM). This interferometer was developed to aim to measure the shape of complex plane, such as aspherical plane. It is difficult for interferometer to measure such a surface which include large inclination, because of the problem of saturation of interference fringe. To overcome this problem, and to enlarge the dynamic range of interferometer, we attempted to combine interferometer and zero-method. Zero-method is characterized by its wide dynamic range. To apply zero-method to interferometer, SLM is adopted to configure variable reference surface. The basic configuration of the developed interferometer is Twyman-Green interferometer. A SLM is placed instead of reference mirror. In this interferometer, the shape of a target is measured using interference between object wave front and reference wave front that is generated using SLM. At first, the SLM generates flat wave front. And the detected phase map is fed back to the SLM. Then the difference between object wave front and detected phase map in the first turn. The operation is recursively repeated until the phase range of detected phase map becomes under the threshold. Then the generated wave front should become equal to the target shape. In this report, the basic idea of zeromethod interferometer using LCoS-SLM is verified through several numbers of simulative experiments.

  13. Design of a high-order front tracking method in 2D

    NASA Astrophysics Data System (ADS)

    Vahab, Mehdi

    This document presents a proposal for a new high-order front tracking method in 2D. A thorough review of existing methods for moving and/or irregular boundaries is presented. From this review, the 1D front-tracking approach of Gatti-Bono emerges as the most promising starting point for a higher-dimensional method. The Gatti-Bono method in 1D is then explained in detail, and a 2D extension is proposed. This extension incorporates a number of ideas from the literature on embedded boundary methods for stationary irregular geometries.

  14. Dynamic vacuum analysis for APS high heat flux beamline front ends using optical ray-tracing simulation methods

    SciTech Connect

    Xu, S.; Nielsen, R.W.

    1992-01-01

    The high-power and high-flux x-ray beams produced by third generation synchrotron radiation sources such as the Advanced Photon Source (APS) can cause significantly high gas desorption rates on beamline front-end components if beam missteering occurs. The effect of this gas desorption needs to be understood for dynamic vacuum analysis. To simulate beam missteering conditions, optical ray-tracing methods have been employed. The results of the ray-tracing analysis have been entered into a system-oriented vacuum program to provide dynamic vacuum calculations for determination of pumping requirements for the beamline front-ends. The APS will provide several types of synchrotron radiation sources, for example, undulators, wigglers, and bending magnets. For the purpose of this study, the wiggler source was chosen as a worst case'' scenario due to its high photon flux, high beam power, and relatively large beam cross section.

  15. Dynamic vacuum analysis for APS high heat flux beamline front ends using optical ray-tracing simulation methods

    SciTech Connect

    Xu, S.; Nielsen, R.W.

    1992-09-01

    The high-power and high-flux x-ray beams produced by third generation synchrotron radiation sources such as the Advanced Photon Source (APS) can cause significantly high gas desorption rates on beamline front-end components if beam missteering occurs. The effect of this gas desorption needs to be understood for dynamic vacuum analysis. To simulate beam missteering conditions, optical ray-tracing methods have been employed. The results of the ray-tracing analysis have been entered into a system-oriented vacuum program to provide dynamic vacuum calculations for determination of pumping requirements for the beamline front-ends. The APS will provide several types of synchrotron radiation sources, for example, undulators, wigglers, and bending magnets. For the purpose of this study, the wiggler source was chosen as a ``worst case`` scenario due to its high photon flux, high beam power, and relatively large beam cross section.

  16. Flame front tracking by laser induced fluorescence spectroscopy and advanced image analysis

    NASA Astrophysics Data System (ADS)

    Abu-Gharbieh, Rafeef; Hamarneh, Ghassan; Gustavsson, Thomas; Kaminski, Clemens

    2001-02-01

    This paper presents advanced image analysis methods for extracting information from high speed Planar Laser Induced Fluorescence (PLIF) data obtained from turbulent flames. The application of non-linear anisotropic diffusion filtering and of Active Contour Models (Snakes) is described to isolate flame boundaries. In a subsequent step, the detected flame boundaries are tracked in time using a frequency domain contour interpolation scheme. The implementations of the methods are described and possible applications of the techniques are discussed.

  17. Sorting method to extend the dynamic range of the Shack-Hartmann wave-front sensor

    SciTech Connect

    Lee, Junwon; Shack, Roland V.; Descour, Michael R

    2005-08-10

    We propose a simple and powerful algorithm to extend the dynamic range of a Shack-Hartmann wave-front sensor. In a conventional Shack-Hartmann wave-front sensor the dynamic range is limited by the f-number of a lenslet, because the focal spot is required to remain in the area confined by the single lenslet. The sorting method proposed here eliminates such a limitation and extends the dynamic range by tagging each spot in a special sequence. Since the sorting method is a simple algorithm that does not change the measurement configuration, there is no requirement for extra hardware, multiple measurements, or complicated algorithms. We not only present the theory and a calculation example of the sorting method but also actually implement measurement of a highly aberrated wave front from nonrotational symmetric optics.

  18. Springback Reduction in Stamping of Front Side Member with a Response Surface Method

    SciTech Connect

    Song, Jung-Han; Huh, Hoon; Kim, Se-Ho; Park, Sung-Ho

    2005-08-05

    Springback is a common phenomenon in sheet metal forming since the elastic recovery of the internal stresses is induced after removal of the tooling. The numerical analysis of springback is a complicated time-consuming job and its result is greatly effected by a type of the yield function, finite elements used and the constraint condition for eliminating a rigid body motion. In this paper, optimization of the draw-bead force is carried out utilizing the response surface method in order to reduce springback and improve shape accuracy of a deep drawn product. In the optimization process, the tendency of springback is evaluated qualitatively without springback simulation usually done with the implicit solving scheme. Instead of springback simulation, the amount of stress deviation along the thickness direction in the deep drawn product is used as an indicator of springback. The stamping process is analyzed for a front side member formed with advanced high strength steel (AHSS) sheets such as DP60. The analysis procedure fully covers the binder-wrap, stamping, trimming and springback processes with the commercial elasto-plastic finite element code LS-DYNA 3D. The effect of the restraining force of draw-beads is confirmed with the decreased stress deviation. The analysis result shown in the final springback simulation demonstrates that the present analysis provides a guideline for controlling the evolution of springback based on the finite element simulation of complicated auto-body members.

  19. Springback Reduction in Stamping of Front Side Member with a Response Surface Method

    NASA Astrophysics Data System (ADS)

    Song, Jung-Han; Huh, Hoon; Kim, Se-Ho; Park, Sung-Ho

    2005-08-01

    Springback is a common phenomenon in sheet metal forming since the elastic recovery of the internal stresses is induced after removal of the tooling. The numerical analysis of springback is a complicated time-consuming job and its result is greatly effected by a type of the yield function, finite elements used and the constraint condition for eliminating a rigid body motion. In this paper, optimization of the draw-bead force is carried out utilizing the response surface method in order to reduce springback and improve shape accuracy of a deep drawn product. In the optimization process, the tendency of springback is evaluated qualitatively without springback simulation usually done with the implicit solving scheme. Instead of springback simulation, the amount of stress deviation along the thickness direction in the deep drawn product is used as an indicator of springback. The stamping process is analyzed for a front side member formed with advanced high strength steel (AHSS) sheets such as DP60. The analysis procedure fully covers the binder-wrap, stamping, trimming and springback processes with the commercial elasto-plastic finite element code LS-DYNA 3D. The effect of the restraining force of draw-beads is confirmed with the decreased stress deviation. The analysis result shown in the final springback simulation demonstrates that the present analysis provides a guideline for controlling the evolution of springback based on the finite element simulation of complicated auto-body members.

  20. Radiation correction method for infrared polarization imaging system with front-mounted polarizer.

    PubMed

    Li, Shuo; Jin, Weiqi; Xia, Runqiu; Li, Li; Wang, Xia

    2016-11-14

    The architecture of imaging polarimeters with front-mounted polarizer generally used in infrared imaging polarimetry has significant influence on the imaging process of the systems and further calculation of the polarization information of the observed scenario. In this study, the imaging process of infrared polarization imaging system with front-mounted polarizer is analyzed, a radiation correction method based on the modified infrared imaging model of such a system is proposed, and both laboratory and outdoor experiments are performed to verify its effect. Experimental results show that the proposed correction method can effectively eliminate the adverse effects of the radiation introduced by front-mounted polarizer, which significantly reduces scene radiation measurement error and improves the calculation accuracy of the polarization information.

  1. Design method of a light emitting diode front fog lamp based on a freeform reflector

    NASA Astrophysics Data System (ADS)

    Wu, Heng; Zhang, Xianmin; Ge, Peng

    2015-09-01

    We propose a method for the design of a light emitting diode front fog lamp based on a freeform reflector. The source-target mapping is used to establish the relationship between the solid angle of the source and the target plane. The reflector is then constructed based on the non-imaging optics theory and Snell's law. A feedback function is deduced from the deviation in the simulated light pattern based on the sampling method. The reflector is then regenerated with feedback modifications and the variance is minimized after several feedbacks. A reflector for the automobile front fog lamp is designed for the OSTAR Headlamp LED source whose emitting surface is 2.8 mm×2.5 mm. Simulation results indicate that the light performance can well meet the standard of the front fog lamps in ECE R19 Revision 7.

  2. Design method of a light-emitting diode front fog lamp based on a freeform reflector

    NASA Astrophysics Data System (ADS)

    Wu, Heng; Zhang, Xianmin; Ge, Peng

    2015-06-01

    We propose a method for the design of a light-emitting diode front fog lamp based on a freeform reflector. The source-target mapping is used to establish the relationship between the solid angle of the source and the target plane. The reflector is then constructed based on the non-imaging optics theory and Snell's Law. A feedback function is deduced from the deviation in the simulated light pattern based on the sampling method. The reflector is then regenerated with feedback modifications and the variance is minimized after several feedbacks. A reflector for the automobile front fog lamp is designed for the OSTAR Headlamp LED source whose emitting surface is 2.8 mm×2.5 mm. Simulation results indicate that the light performance can well meet the standard of the front fog lamps in ECE R19 Revision 7.

  3. Apparatus for characterizing the temporo-spatial properties of a dynamic fluid front and method thereof

    DOEpatents

    Battiste, Richard L.

    2007-12-25

    Methods and apparatus are described for characterizing the temporal-spatial properties of a dynamic fluid front within a mold space while the mold space is being filled with fluid. A method includes providing a mold defining a mold space and having one or more openings into the mold space; heating a plurality of temperature sensors that extend into the mold space; injecting a fluid into the mold space through the openings, the fluid experiencing a dynamic fluid front while filling the mold space with the fluid; and characterizing temporal-spatial properties of the dynamic fluid front by monitoring a temperature of each of the plurality of heated temperature sensors while the mold space is being filled with the fluid. An apparatus includes a mold defining a mold space; one or more openings for introducing a fluid into the mold space and filling the mold space with the fluid, the fluid experiencing a dynamic fluid front while filling the mold space; a plurality of heated temperature sensors extending into the mold space; and a computer coupled to the plurality of heated temperature sensors for characterizing the temporal-spatial properties of the dynamic fluid front.

  4. Apparatus for characterizing the temporo-spatial properties of a dynamic fluid front and method thereof

    DOEpatents

    Battiste, Richard L

    2013-12-31

    Methods and apparatus are described for characterizing the temporal-spatial properties of a dynamic fluid front within a mold space while the mold space is being filled with fluid. A method includes providing a mold defining a mold space and having one or more openings into the mold space; heating a plurality of temperature sensors that extend into the mold space; injecting a fluid into th emold space through the openings, the fluid experiencing a dynamic fluid front while filling the mold space with a fluid; and characterizing temporal-spatial properties of the dynamic fluid front by monitoring a termperature of each of the plurality of heated temperature sensors while the mold space is being filled with the fluid. An apparatus includes a mold defining a mold space; one or more openings for introducing a fluid into th emold space and filling the mold space with the fluid, the fluid experiencing a dynamic fluid front while filling the mold space; a plurality of heated temperature sensors extending into the mold space; and a computer coupled to the plurality of heated temperature sensors for characterizing the temporal-spatial properties of the dynamic fluid front.

  5. The Advanced Exploration Systems Water Recovery Project: Innovation on 2 Fronts

    NASA Technical Reports Server (NTRS)

    Sarguisingh, Miriam M.; Neumeyer, Derek; Shull, Sarah

    2012-01-01

    As NASA looks forward to sending humans farther away from Earth, we will have to develop a transportation architecture that is highly reliable and that can sustain life for long durations without the benefit of Earth s proximity for continuous resupply or even operational guidance. NASA has consistently been challenged with performing great feats of innovation, but particularly in this time of economic stress, we are challenged to go farther with less. The Advanced Exploration Systems (AES) projects were implemented to address both of these needs by not only developing innovative technologies, but by incorporating innovative management styles and processes that foster the needed technical innovation given a small amount of resources. This presentation explains how the AES Water Recovery Project is exhibiting innovation on both fronts; technical and process. The AES Water Recovery Project (WRP) is actively engineering innovative technologies in order to maximize the efficiency of water recovery. The development of reliable, energy-efficient, and low-mass spacecraft systems to provide environmental control and life support (ECLS) is critical to enable long-duration human missions outside of low-Earth orbit. Recycling of life support consumables is necessary to reduce resupply mass and provide for vehicle autonomy. To address this, the WRP is working on a rotary distiller that has shown enhanced performance over the state-of-the-art (SOA). Additionally, the WRP is looking at innovative ways to address issues present in the state-of-the-art (SOA) systems pertaining to toxicity and calcium scale buildup. As an AES project, the WRP has a more streamlined Skunk Works like approach to technology development intended to reduce overhead but achieve a more refined end product. The project has incorporated key partnerships between NASA centers as well as between NASA and industry. A minimal project management style has been implemented such that risks are managed and

  6. Apparatus and method for phase fronts based on superluminal polarization current

    DOEpatents

    Singleton, John [Los Alamos, NM; Ardavan, Houshang [Cambridge, GB; Ardavan, Arzhang [Cambridge, GB

    2012-02-28

    An apparatus and method for a radiation source involving phase fronts emanating from an accelerated, oscillating polarization current whose distribution pattern moves superluminally (that is, faster than light in vacuo). Theoretical predictions and experimental measurements using an existing prototype superluminal source show that the phase fronts from such a source can be made to be very complex. Consequently, it will be very difficult for an aircraft imaged by such a radiation to detect where this radiation has come from. Moreover, the complexity of the phase fronts makes it almost impossible for electronics on an aircraft to synthesize a rogue reflection. A simple directional antenna and timing system should, on the other hand, be sufficient for the radar operators to locate the aircraft, given knowledge of their own source's speed and modulation pattern.

  7. Domain Decomposition By the Advancing-Partition Method

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar Z.

    2008-01-01

    A new method of domain decomposition has been developed for generating unstructured grids in subdomains either sequentially or using multiple computers in parallel. Domain decomposition is a crucial and challenging step for parallel grid generation. Prior methods are generally based on auxiliary, complex, and computationally intensive operations for defining partition interfaces and usually produce grids of lower quality than those generated in single domains. The new technique, referred to as "Advancing Partition," is based on the Advancing-Front method, which partitions a domain as part of the volume mesh generation in a consistent and "natural" way. The benefits of this approach are: 1) the process of domain decomposition is highly automated, 2) partitioning of domain does not compromise the quality of the generated grids, and 3) the computational overhead for domain decomposition is minimal. The new method has been implemented in NASA's unstructured grid generation code VGRID.

  8. Method and apparatus for generating radiation utilizing DC to AC conversion with a conductive front

    DOEpatents

    Dawson, J.M.; Mori, W.B.; Lai, C.H.; Katsouleas, T.C.

    1998-07-14

    Method and apparatus ar disclosed for generating radiation of high power, variable duration and broad tunability over several orders of magnitude from a laser-ionized gas-filled capacitor array. The method and apparatus convert a DC electric field pattern into a coherent electromagnetic wave train when a relativistic ionization front passes between the capacitor plates. The frequency and duration of the radiation is controlled by the gas pressure and capacitor spacing. 4 figs.

  9. Method and apparatus for generating radiation utilizing DC to AC conversion with a conductive front

    DOEpatents

    Dawson, John M.; Mori, Warren B.; Lai, Chih-Hsiang; Katsouleas, Thomas C.

    1998-01-01

    Method and apparatus for generating radiation of high power, variable duration and broad tunability over several orders of magnitude from a laser-ionized gas-filled capacitor array. The method and apparatus convert a DC electric field pattern into a coherent electromagnetic wave train when a relativistic ionization front passes between the capacitor plates. The frequency and duration of the radiation is controlled by the gas pressure and capacitor spacing.

  10. Systems and methods for advanced ultra-high-performance InP solar cells

    DOEpatents

    Wanlass, Mark

    2017-03-07

    Systems and Methods for Advanced Ultra-High-Performance InP Solar Cells are provided. In one embodiment, an InP photovoltaic device comprises: a p-n junction absorber layer comprising at least one InP layer; a front surface confinement layer; and a back surface confinement layer; wherein either the front surface confinement layer or the back surface confinement layer forms part of a High-Low (HL) doping architecture; and wherein either the front surface confinement layer or the back surface confinement layer forms part of a heterointerface system architecture.

  11. Study of Crystal Growth and Solute Precipitation through Front Tracking Method

    SciTech Connect

    Li, X.; Glimm, J.; Jiao, X.; Peyser, C., Zhao, Y.

    2010-03-01

    Crystal growth and solute precipitation is a Stefan problem. It is a free boundary problem for a parabolic partial differential equation with a time-dependent phase interface. The velocity of the moving interface between solute and crystal is a local function. The dendritic structure of the crystal interface, which develops dynamically, requires high resolution of the interface geometry. These facts make the Lagrangian front tracking method well suited for the problem. In this paper, we introduce an upgraded version of the front tracking code and its associated algorithms for the numerical study of crystal formation. We compare our results with the smoothed particle hydrodynamics method (SPH) in terms of the crystal fractal dimension with its dependence on the Damkohler number and density ratio.

  12. Method for characterization of the rate of movement of an oxidation front in cementitious materials

    SciTech Connect

    Almond, Philip M.; Langton, Christine A.; Stefanko, David B.

    2016-03-01

    Disclosed are methods for determining the redox condition of cementitious materials. The methods are leaching methods that utilize a redox active transition metal indicator that is present in the cementitious material and exhibits variable solubility depending upon the oxidation state of the indicator. When the leaching process is carried out under anaerobic conditions, the presence or absence of the indicator in the leachate can be utilized to determine the redox condition of and location of the oxidation front in the material that has been subjected to the leaching process.

  13. Method of fabricating conductive electrodes on the front and backside of a thin film structure

    DOEpatents

    Tabada, Phillipe J.; Tabada, legal representative, Melody; Pannu, Satinderpall S.

    2011-05-22

    A method of fabricating a thin film device having conductive front and backside electrodes or contacts. Top-side cavities are first formed on a first dielectric layer, followed by the deposition of a metal layer on the first dielectric layer to fill the cavities. Defined metal structures are etched from the metal layer to include the cavity-filled metal, followed by depositing a second dielectric layer over the metal structures. Additional levels of defined metal structures may be formed in a similar manner with vias connecting metal structures between levels. After a final dielectric layer is deposited, a top surface of a metal structure of an uppermost metal layer is exposed through the final dielectric layer to form a front-side electrode, and a bottom surface of a cavity-filled portion of a metal structure of a lowermost metal layer is also exposed through the first dielectric layer to form a back-side electrode.

  14. Adaptive moving mesh methods for simulating one-dimensional groundwater problems with sharp moving fronts

    USGS Publications Warehouse

    Huang, W.; Zheng, Lingyun; Zhan, X.

    2002-01-01

    Accurate modelling of groundwater flow and transport with sharp moving fronts often involves high computational cost, when a fixed/uniform mesh is used. In this paper, we investigate the modelling of groundwater problems using a particular adaptive mesh method called the moving mesh partial differential equation approach. With this approach, the mesh is dynamically relocated through a partial differential equation to capture the evolving sharp fronts with a relatively small number of grid points. The mesh movement and physical system modelling are realized by solving the mesh movement and physical partial differential equations alternately. The method is applied to the modelling of a range of groundwater problems, including advection dominated chemical transport and reaction, non-linear infiltration in soil, and the coupling of density dependent flow and transport. Numerical results demonstrate that sharp moving fronts can be accurately and efficiently captured by the moving mesh approach. Also addressed are important implementation strategies, e.g. the construction of the monitor function based on the interpolation error, control of mesh concentration, and two-layer mesh movement. Copyright ?? 2002 John Wiley and Sons, Ltd.

  15. Simulations of Coalescence and Breakup of Interfaces Using a 3D Front-tracking Method

    NASA Astrophysics Data System (ADS)

    Lu, Jiacai; Tryggvason, Gretar

    2015-11-01

    Direct Numerical Simulations (DNS) of complex multiphase flows with coalescing and breaking-up of interfaces are conducted using a 3D front-tracking method. Front-tracking method has been successfully used in DNS of turbulent channel bubbly flows and many other multiphase flows, but as the void fraction increases changes in the interface topology, though coalescence and breakup, become more common and have to be accounted for. Topology changes have often been identified as a challenge for front tracking, where the interface is represented using a triangular mesh, but here we present an efficient algorithm to change the topology of triangular elements of interfaces. In the current implementation we have not included any small-scale attractive forces so thin films coalesce either at prescribed times or when their thickness reaches a given value. Simulations of the collisions of two drops and comparisons with experimental results have been used to validate the algorithm but the main applications have been to flow regime transitions in gas-liquid flows in pressure driven channel flows. The evolution of flow, including flow rate, wall shear, projected interface areas, pseudo-turbulence, and the average size of the various flow structures, is examined as the topology of the interface changes through coalescence and breakup. Research supported by DOE (CASL).

  16. Development/Demonstration of an Advanced Oxy-Fuel Front-End System

    SciTech Connect

    Mighton, Steven, J.

    2007-08-06

    Owens Corning and other glass manufacturers have used oxy-fuel combustion technology successfully in furnaces to reduce emissions, increase throughput, reduce fuel consumption and, depending on the costs of oxygen and fuel, reduce energy costs. The front end of a fiberglass furnace is the refractory channel system that delivers glass from the melter to the forming process. After the melter, it is the second largest user of energy in a fiberglass plant. A consortium of glass companies and suppliers, led by Owens Corning, was formed to develop and demonstrate oxy/fuel combustion technology for the front end of a fiberglass melter, to demonstrate the viability of this energy saving technology to the U.S. glass industry, as a D.O.E. sponsored project. The project goals were to reduce natural gas consumption and CO2 green house gas emissions by 65 to 70% and create net cost savings after the purchase of oxygen to achieve a project payback of less than 2 years. Project results in Jackson, TN included achieving a 56% reduction in gas consumption and CO2 emissions. A subsequent installation in Guelph ON, not impacted by unrelated operational changes in Jackson, achieved a 64% reduction. Using the more accurate 64% reduction in the payback calculation yielded a 2.2 year payback in Jackson. The installation of the demonstration combustion system saves 77,000 DT/yr of natural gas or 77 trillion Btu/yr and eliminates 4500 tons/yr of CO2 emissions. This combustion system is one of several energy and green house gas reduction technologies being adopted by Owens Corning to achieve aggressive goals relating to the company’s global facility environmental footprint.

  17. Numerical study of dendritic growth during solidification using front-tracking method

    NASA Astrophysics Data System (ADS)

    Jaafar, Mohamad Ali; Gibout, Stéphane; Rousse, Daniel; Bédécarrats, Jean-Pierre

    2016-09-01

    A two dimensional front-tracking method is developed in order to model dendritic growth during solidification processes of pure substances. The method uses a sequential set of moving marker points to describe and track the liquid-solid interface which evolves over a fixed background mesh describing the whole medium. The code behaviour is first checked by a simple stable case of solidification to provide homogeneous velocity at the interface. Then, test examples of unstable solidification cases considering different modes of anisotropy are performed. Finally, interface evolution, with primary and secondary branches, is described, showing the ability of the code to study realistic dendritic growth characteristics.

  18. Advanced Optics for a Full Quasi-Optical Front Steering ECRH Upper Launcher for ITER

    SciTech Connect

    Moro, A.; Alessi, E.; Bruschi, A.; Platania, P.; Sozzi, C.; Chavan, R.; Collazos, A.; Goodman, T. P.; Udintsev, V. S.; Henderson, M. A.

    2009-11-26

    A full quasi-optical setup for the internal optics of the Front Steering Electron Cyclotron Resonance Heating (ECRH) Upper Launcher for ITER was designed, proving to be feasible and favorable in terms of additional flexibility and cost reduction with respect to the former design. This full quasi-optical solution foresees the replacement of the mitre-bends in the final section of the launcher with dedicated free-space mirrors to realize the last changes of directions in the launcher. A description of the launcher is given and its advantages presented. The parameters of the expected output beams as well as preliminary evaluations of truncation effects with the physical optics GRASP code are shown. Moreover, a study of mitre-bends replacement with single mirrors for multiple beams is described. In principle it could allow the beams to be larger at the mirror locations (with a further decrease of the peak power density due to partial overlapping) and has the additional advantage to get a larger opening with compressed beams to avoid conflicts with side-walls port. Constraints on the setup, arising both from the resulting beam characteristics in the space of free parameters and from mechanical requirements are taken into account in the analysis.

  19. Advances in Front-end Enabling Technologies for Thermal Infrared ` THz Torch' Wireless Communications

    NASA Astrophysics Data System (ADS)

    Hu, Fangjing; Lucyszyn, Stepan

    2016-09-01

    The thermal (emitted) infrared frequency bands (typically 20-40 and 60-100 THz) are best known for remote sensing applications that include temperature measurement (e.g. non-contacting thermometers and thermography), night vision and surveillance (e.g. ubiquitous motion sensing and target acquisition). This unregulated part of the electromagnetic spectrum also offers commercial opportunities for the development of short-range secure communications. The ` THz Torch' concept, which fundamentally exploits engineered blackbody radiation by partitioning thermally generated spectral radiance into pre-defined frequency channels, was recently demonstrated by the authors. The thermal radiation within each channel can be independently pulse-modulated, transmitted and detected, to create a robust form of short-range secure communications within the thermal infrared. In this paper, recent progress in the front-end enabling technologies associated with the THz Torch concept is reported. Fundamental limitations of this technology are discussed; possible engineering solutions for further improving the performance of such thermal-based wireless links are proposed and verified either experimentally or through numerical simulations. By exploring a raft of enabling technologies, significant enhancements to both data rate and transmission range can be expected. With good engineering solutions, the THz Torch concept can exploit nineteenth century physics with twentieth century multiplexing schemes for low-cost twenty-first century ubiquitous applications in security and defence.

  20. Advanced method for oligonucleotide deprotection

    PubMed Central

    Surzhikov, Sergey A.; Timofeev, Edward N.; Chernov, Boris K.; Golova, Julia B.; Mirzabekov, Andrei D.

    2000-01-01

    A new procedure for rapid deprotection of synthetic oligodeoxynucleotides has been developed. While all known deprotection methods require purification to remove the residual protective groups (e.g. benzamide) and insoluble silicates, the new procedure based on the use of an ammonia-free reagent mixture allows one to avoid the additional purification steps. The method can be applied to deprotect the oligodeoxynucleotides synthesized by using the standard protected nucleoside phosphoramidites dGiBu, dCBz and dABz. PMID:10734206

  1. Advanced Fine Particulate Characterization Methods

    SciTech Connect

    Steven Benson; Lingbu Kong; Alexander Azenkeng; Jason Laumb; Robert Jensen; Edwin Olson; Jill MacKenzie; A.M. Rokanuzzaman

    2007-01-31

    The characterization and control of emissions from combustion sources are of significant importance in improving local and regional air quality. Such emissions include fine particulate matter, organic carbon compounds, and NO{sub x} and SO{sub 2} gases, along with mercury and other toxic metals. This project involved four activities including Further Development of Analytical Techniques for PM{sub 10} and PM{sub 2.5} Characterization and Source Apportionment and Management, Organic Carbonaceous Particulate and Metal Speciation for Source Apportionment Studies, Quantum Modeling, and High-Potassium Carbon Production with Biomass-Coal Blending. The key accomplishments included the development of improved automated methods to characterize the inorganic and organic components particulate matter. The methods involved the use of scanning electron microscopy and x-ray microanalysis for the inorganic fraction and a combination of extractive methods combined with near-edge x-ray absorption fine structure to characterize the organic fraction. These methods have direction application for source apportionment studies of PM because they provide detailed inorganic analysis along with total organic and elemental carbon (OC/EC) quantification. Quantum modeling using density functional theory (DFT) calculations was used to further elucidate a recently developed mechanistic model for mercury speciation in coal combustion systems and interactions on activated carbon. Reaction energies, enthalpies, free energies and binding energies of Hg species to the prototype molecules were derived from the data obtained in these calculations. Bimolecular rate constants for the various elementary steps in the mechanism have been estimated using the hard-sphere collision theory approximation, and the results seem to indicate that extremely fast kinetics could be involved in these surface reactions. Activated carbon was produced from a blend of lignite coal from the Center Mine in North Dakota and

  2. Recent advances in lattice Boltzmann methods

    SciTech Connect

    Chen, S.; Doolen, G.D.; He, X.; Nie, X.; Zhang, R.

    1998-12-31

    In this paper, the authors briefly present the basic principles of lattice Boltzmann method and summarize recent advances of the method, including the application of the lattice Boltzmann method for fluid flows in MEMS and simulation of the multiphase mixing and turbulence.

  3. Thermo-mechanical analysis of fixed mask 1 for the Advanced Photon Source insertion device front ends

    SciTech Connect

    Nian, H.L.T.; Shu, D.; Sheng, I.C.A.; Kuzay, T.M.

    1993-10-01

    The first fixed mask (FM1) is one of the critical elements on the insertion device front ends of the beamlines at the Advanced Photon Source (APS) now under construction at Argonne National Laboratory (ANL). The heat flux from the APS undulators is enormous. For example, FM1 placed at a distance of 16 m from the Undulator A source will be subjected to 519 W/mm{sup 2} at normal incidence with a total power of 3.8 kW. Due to a high localized thermal gradient on this component, inclined geometry (1.5{degree}) is used in the design to spread the footprint of the x-ray beam. A box-cone-shape geometry was designed due to the limited space available in the front end. The box shape is a highly constrained geometry, which induces larger stress levels than would occur in a plate or a tube. In order to handle the expected higher stress and the stress concentration at the corners, a single Glidcop block (rather than copper) was used in the construction. The FM1 uses an enhanced heat transfer mechanism developed at Argonne National Laboratory, which increases the convective heat transfer coefficient to about 3 W/cm{sup 2}{center_dot}{degree}C with single-phase water as the coolant. The authors simulated the location of the x-ray beam in several places to cover the worst possible case. The maximum temperature (about 180{degree}C) occurs when the beam hits the center of horizontal surface. The maximum effective stress (about 313 MPa) occurs when the x-ray beam hits about the corners.

  4. Reconstruction of multiple gastric electrical wave fronts using potential-based inverse methods.

    PubMed

    Kim, J H K; Pullan, A J; Cheng, L K

    2012-08-21

    One approach for non-invasively characterizing gastric electrical activity, commonly used in the field of electrocardiography, involves solving an inverse problem whereby electrical potentials on the stomach surface are directly reconstructed from dense potential measurements on the skin surface. To investigate this problem, an anatomically realistic torso model and an electrical stomach model were used to simulate potentials on stomach and skin surfaces arising from normal gastric electrical activity. The effectiveness of the Greensite-Tikhonov or the Tikhonov inverse methods were compared under the presence of 10% Gaussian noise with either 84 or 204 body surface electrodes. The stability and accuracy of the Greensite-Tikhonov method were further investigated by introducing varying levels of Gaussian signal noise or by increasing or decreasing the size of the stomach by 10%. Results showed that the reconstructed solutions were able to represent the presence of propagating multiple wave fronts and the Greensite-Tikhonov method with 204 electrodes performed best (correlation coefficients of activation time: 90%; pacemaker localization error: 3 cm). The Greensite-Tikhonov method was stable with Gaussian noise levels up to 20% and 10% change in stomach size. The use of 204 rather than 84 body surface electrodes improved the performance; however, for all investigated cases, the Greensite-Tikhonov method outperformed the Tikhonov method.

  5. Reconstruction of multiple gastric electrical wave fronts using potential-based inverse methods

    NASA Astrophysics Data System (ADS)

    Kim, J. H. K.; Pullan, A. J.; Cheng, L. K.

    2012-08-01

    One approach for non-invasively characterizing gastric electrical activity, commonly used in the field of electrocardiography, involves solving an inverse problem whereby electrical potentials on the stomach surface are directly reconstructed from dense potential measurements on the skin surface. To investigate this problem, an anatomically realistic torso model and an electrical stomach model were used to simulate potentials on stomach and skin surfaces arising from normal gastric electrical activity. The effectiveness of the Greensite-Tikhonov or the Tikhonov inverse methods were compared under the presence of 10% Gaussian noise with either 84 or 204 body surface electrodes. The stability and accuracy of the Greensite-Tikhonov method were further investigated by introducing varying levels of Gaussian signal noise or by increasing or decreasing the size of the stomach by 10%. Results showed that the reconstructed solutions were able to represent the presence of propagating multiple wave fronts and the Greensite-Tikhonov method with 204 electrodes performed best (correlation coefficients of activation time: 90%; pacemaker localization error: 3 cm). The Greensite-Tikhonov method was stable with Gaussian noise levels up to 20% and 10% change in stomach size. The use of 204 rather than 84 body surface electrodes improved the performance; however, for all investigated cases, the Greensite-Tikhonov method outperformed the Tikhonov method.

  6. Advanced radioactive waste assay methods: Final report

    SciTech Connect

    Cline, J.E.; Robertson, D.E.; DeGroot, S.E.

    1987-11-01

    This report describes an evaluation of advanced methodologies for the radioassay of low power-plant low-level radioactive waste for compliance with the 10CFR61 classification rules. The project evaluated current assay practices in ten operating plants and identified areas where advanced methods would apply, studied two direct-assay methodologies, demonstrated these two techniques on radwaste in four operating plants and on irradiated components in two plants, and developed techniques for obtaining small representative aliquots from larger samples and for enhancing the /sup 144/Ce activity analysis in samples of waste. The study demonstrated the accuracy, practicality, and ALARA aspects of advanced methods and indicates that cost savings, resulting from the accuracy improvement and reduction in sampling requirements can be significant. 24 refs., 60 figs., 67 tabs.

  7. Advanced analysis methods in particle physics

    SciTech Connect

    Bhat, Pushpalatha C.; /Fermilab

    2010-10-01

    Each generation of high energy physics experiments is grander in scale than the previous - more powerful, more complex and more demanding in terms of data handling and analysis. The spectacular performance of the Tevatron and the beginning of operations of the Large Hadron Collider, have placed us at the threshold of a new era in particle physics. The discovery of the Higgs boson or another agent of electroweak symmetry breaking and evidence of new physics may be just around the corner. The greatest challenge in these pursuits is to extract the extremely rare signals, if any, from huge backgrounds arising from known physics processes. The use of advanced analysis techniques is crucial in achieving this goal. In this review, I discuss the concepts of optimal analysis, some important advanced analysis methods and a few examples. The judicious use of these advanced methods should enable new discoveries and produce results with better precision, robustness and clarity.

  8. Aggregate supply and demand modeling using GIS methods for the front range urban corridor, Colorado

    NASA Astrophysics Data System (ADS)

    Karakas, Ahmet; Turner, Keith

    2004-07-01

    The combined use of allocation modeling and geographical information system (GIS) technologies for providing quantitative assessments of aggregate supply and demand is evaluated using representative data for the Front Range Urban Corridor (FRUC) in Colorado. The FRUC extends from the Colorado-Wyoming border to south of Colorado Springs, and includes Denver and the major urban growth regions of Colorado. In this area, aggregate demand is high and is increasing in response to population growth. Neighborhood opposition to the establishment of new pits and quarries and the depletion of many deposits are limiting aggregate supplies. Many sources are already covered by urban development or eliminated from production by zoning. Transport of aggregate by rail from distant resources may be required in the future. Two allocation-modeling procedures are tested in this study. Network analysis procedures provided within the ARC/INFO software, are unsatisfactory. Further aggregate allocation modeling used a model specifically designed for this task; a modified version of an existing Colorado School of Mines allocation model allows for more realistic market analyses. This study evaluated four scenarios. The entire region was evaluated with a scenario reflecting the current market and by a second scenario in which some existing suppliers were closed down and new potential suppliers were activated. The conditions within the Denver metropolitan area were studied before and after the introduction of three possible rail-to-truck aggregate distribution centers. GIS techniques are helpful in developing the required database to describe the Front Range Urban Corridor aggregate market conditions. GIS methods allow the digital representation of the regional road network, and the development of a distance matrix relating all suppliers and purchasers.

  9. Cost estimating methods for advanced space systems

    NASA Technical Reports Server (NTRS)

    Cyr, Kelley

    1988-01-01

    The development of parametric cost estimating methods for advanced space systems in the conceptual design phase is discussed. The process of identifying variables which drive cost and the relationship between weight and cost are discussed. A theoretical model of cost is developed and tested using a historical data base of research and development projects.

  10. A method for tracking subsurface fronts of stress-induced permeability enhancement

    NASA Astrophysics Data System (ADS)

    Lewis, K. C.

    2012-12-01

    The coupled interactions in fractured geological media between thermal-hydrologic-mechanical (THM) and chemical effects are expected to be important in many engineering applications including CO2 sequestration, geothermal energy production, oil and gas production, nuclear waste isolation, and arctic permafrost. Large changes in pressures, temperatures, and saturations can result due to injection/withdrawal of fluids or emplaced heat sources. Phase changes or rock failure often occur in an abrupt fashion, characterized by a sharp front of discontinuity with relatively small changes in properties on either side of the front. These changes can modify the formation permeability in a manner that can often be approximated by a step-function-like dependence. Such behavior has motivated us to use an analogy to the classical Stefan problem; we construct evolution equations for the fluid pore pressure on both sides of a propagating stress induced damage front for the case of planar front geometry. Closed form expressions are derived for the position of the damage front and the observable surface mass flow rate as functions of time for planar, spherical, and cylindrical damage front geometries. Isothermal, pressure induced damage is discussed as well as damage dominated by thermal effects. Model predictions are shown to agree with those of a less general fracture model as well as with field data consisting of measured mass flow rates over a two week period. Finally, we discuss extensions of the basic model to more complex damage front geometries.

  11. Advanced numerical methods in mesh generation and mesh adaptation

    SciTech Connect

    Lipnikov, Konstantine; Danilov, A; Vassilevski, Y; Agonzal, A

    2010-01-01

    Numerical solution of partial differential equations requires appropriate meshes, efficient solvers and robust and reliable error estimates. Generation of high-quality meshes for complex engineering models is a non-trivial task. This task is made more difficult when the mesh has to be adapted to a problem solution. This article is focused on a synergistic approach to the mesh generation and mesh adaptation, where best properties of various mesh generation methods are combined to build efficiently simplicial meshes. First, the advancing front technique (AFT) is combined with the incremental Delaunay triangulation (DT) to build an initial mesh. Second, the metric-based mesh adaptation (MBA) method is employed to improve quality of the generated mesh and/or to adapt it to a problem solution. We demonstrate with numerical experiments that combination of all three methods is required for robust meshing of complex engineering models. The key to successful mesh generation is the high-quality of the triangles in the initial front. We use a black-box technique to improve surface meshes exported from an unattainable CAD system. The initial surface mesh is refined into a shape-regular triangulation which approximates the boundary with the same accuracy as the CAD mesh. The DT method adds robustness to the AFT. The resulting mesh is topologically correct but may contain a few slivers. The MBA uses seven local operations to modify the mesh topology. It improves significantly the mesh quality. The MBA method is also used to adapt the mesh to a problem solution to minimize computational resources required for solving the problem. The MBA has a solid theoretical background. In the first two experiments, we consider the convection-diffusion and elasticity problems. We demonstrate the optimal reduction rate of the discretization error on a sequence of adaptive strongly anisotropic meshes. The key element of the MBA method is construction of a tensor metric from hierarchical edge

  12. Editorial: Latest methods and advances in biotechnology.

    PubMed

    Lee, Sang Yup; Jungbauer, Alois

    2014-01-01

    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli.

  13. 40 CFR 63.488 - Methods and procedures for batch front-end process vent group determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Polymers and Resins § 63.488 Methods and procedures for batch front-end process vent group determination... be based on either organic HAP or TOC emissions. (1) The procedures specified in paragraphs (b... of product. (2) The annual uncontrolled organic HAP or TOC emissions and annual average batch...

  14. Simulation methods for advanced scientific computing

    SciTech Connect

    Booth, T.E.; Carlson, J.A.; Forster, R.A.

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The objective of the project was to create effective new algorithms for solving N-body problems by computer simulation. The authors concentrated on developing advanced classical and quantum Monte Carlo techniques. For simulations of phase transitions in classical systems, they produced a framework generalizing the famous Swendsen-Wang cluster algorithms for Ising and Potts models. For spin-glass-like problems, they demonstrated the effectiveness of an extension of the multicanonical method for the two-dimensional, random bond Ising model. For quantum mechanical systems, they generated a new method to compute the ground-state energy of systems of interacting electrons. They also improved methods to compute excited states when the diffusion quantum Monte Carlo method is used and to compute longer time dynamics when the stationary phase quantum Monte Carlo method is used.

  15. Advanced Bayesian Method for Planetary Surface Navigation

    NASA Technical Reports Server (NTRS)

    Center, Julian

    2015-01-01

    Autonomous Exploration, Inc., has developed an advanced Bayesian statistical inference method that leverages current computing technology to produce a highly accurate surface navigation system. The method combines dense stereo vision and high-speed optical flow to implement visual odometry (VO) to track faster rover movements. The Bayesian VO technique improves performance by using all image information rather than corner features only. The method determines what can be learned from each image pixel and weighs the information accordingly. This capability improves performance in shadowed areas that yield only low-contrast images. The error characteristics of the visual processing are complementary to those of a low-cost inertial measurement unit (IMU), so the combination of the two capabilities provides highly accurate navigation. The method increases NASA mission productivity by enabling faster rover speed and accuracy. On Earth, the technology will permit operation of robots and autonomous vehicles in areas where the Global Positioning System (GPS) is degraded or unavailable.

  16. Use advanced methods to treat wastewater

    SciTech Connect

    Davis, M. )

    1994-08-01

    Common sense guidelines offer plausible, progressive techniques to treat wastewater. Because current and pending local, state and federal regulations are ratcheting lower effluent discharge limits, familiar treatment methods, such as biological, don't meet new restrictions. Now operating facilities must combine traditional methods with advanced remedial options such as thermal, physical, electro and chemical treatments. these new techniques remove organics, metals, nonhazardous dissolved salts, etc., but carry higher operating and installation costs. Due to tighter effluent restrictions and pending zero-discharge initiatives, managers of operating facilities must know and understand the complexity, composition and contaminant concentration of their wastewaters. No one-size-fits-all solution exists. However, guidelines can simplify decision making and help operators nominate the most effective and economical strategy to handle their waste situation. The paper describes the common treatment and the importance of alternatives, then describes biological, electro, physical, thermal, and chemical treatments.

  17. An illustration of the light-front coupled-cluster method in quantum electrodynamics

    SciTech Connect

    Chabysheva, S. S.

    2012-10-23

    A field-theoretic formulation of the exponential-operator technique is applied to a nonperturbative Hamiltonian eigenvalue problem in electrodynamics, quantized in light-front coordinates. Specifically, we consider the dressed-electron state, without positron contributions but with an unlimited number of photons, and compute its anomalous magnetic moment. A simple perturbative solution immediately yields the Schwinger result of {alpha}/2{pi}. The nonperturbative solution, which requires numerical techniques, sums a subset of corrections to all orders in {alpha} and incorporates additional physics.

  18. Advanced fault diagnosis methods in molecular networks.

    PubMed

    Habibi, Iman; Emamian, Effat S; Abdi, Ali

    2014-01-01

    Analysis of the failure of cell signaling networks is an important topic in systems biology and has applications in target discovery and drug development. In this paper, some advanced methods for fault diagnosis in signaling networks are developed and then applied to a caspase network and an SHP2 network. The goal is to understand how, and to what extent, the dysfunction of molecules in a network contributes to the failure of the entire network. Network dysfunction (failure) is defined as failure to produce the expected outputs in response to the input signals. Vulnerability level of a molecule is defined as the probability of the network failure, when the molecule is dysfunctional. In this study, a method to calculate the vulnerability level of single molecules for different combinations of input signals is developed. Furthermore, a more complex yet biologically meaningful method for calculating the multi-fault vulnerability levels is suggested, in which two or more molecules are simultaneously dysfunctional. Finally, a method is developed for fault diagnosis of networks based on a ternary logic model, which considers three activity levels for a molecule instead of the previously published binary logic model, and provides equations for the vulnerabilities of molecules in a ternary framework. Multi-fault analysis shows that the pairs of molecules with high vulnerability typically include a highly vulnerable molecule identified by the single fault analysis. The ternary fault analysis for the caspase network shows that predictions obtained using the more complex ternary model are about the same as the predictions of the simpler binary approach. This study suggests that by increasing the number of activity levels the complexity of the model grows; however, the predictive power of the ternary model does not appear to be increased proportionally.

  19. Domain Decomposition By the Advancing-Partition Method for Parallel Unstructured Grid Generation

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar Z.; Zagaris, George

    2009-01-01

    A new method of domain decomposition has been developed for generating unstructured grids in subdomains either sequentially or using multiple computers in parallel. Domain decomposition is a crucial and challenging step for parallel grid generation. Prior methods are generally based on auxiliary, complex, and computationally intensive operations for defining partition interfaces and usually produce grids of lower quality than those generated in single domains. The new technique, referred to as "Advancing Partition," is based on the Advancing-Front method, which partitions a domain as part of the volume mesh generation in a consistent and "natural" way. The benefits of this approach are: 1) the process of domain decomposition is highly automated, 2) partitioning of domain does not compromise the quality of the generated grids, and 3) the computational overhead for domain decomposition is minimal. The new method has been implemented in NASA's unstructured grid generation code VGRID.

  20. Advanced continuous cultivation methods for systems microbiology.

    PubMed

    Adamberg, Kaarel; Valgepea, Kaspar; Vilu, Raivo

    2015-09-01

    Increasing the throughput of systems biology-based experimental characterization of in silico-designed strains has great potential for accelerating the development of cell factories. For this, analysis of metabolism in the steady state is essential as only this enables the unequivocal definition of the physiological state of cells, which is needed for the complete description and in silico reconstruction of their phenotypes. In this review, we show that for a systems microbiology approach, high-resolution characterization of metabolism in the steady state--growth space analysis (GSA)--can be achieved by using advanced continuous cultivation methods termed changestats. In changestats, an environmental parameter is continuously changed at a constant rate within one experiment whilst maintaining cells in the physiological steady state similar to chemostats. This increases the resolution and throughput of GSA compared with chemostats, and, moreover, enables following of the dynamics of metabolism and detection of metabolic switch-points and optimal growth conditions. We also describe the concept, challenge and necessary criteria of the systematic analysis of steady-state metabolism. Finally, we propose that such systematic characterization of the steady-state growth space of cells using changestats has value not only for fundamental studies of metabolism, but also for systems biology-based metabolic engineering of cell factories.

  1. Advanced electromagnetic methods for aerospace vehicles

    NASA Technical Reports Server (NTRS)

    Balanis, Constantine A.; Sun, Weimin; El-Sharawy, El-Budawy; Aberle, James T.; Birtcher, Craig R.; Peng, Jian; Tirkas, Panayiotis A.; Andrew, William V.; Kokotoff, David; Zavosh, Frank

    1993-01-01

    The Advanced Helicopter Electromagnetics (AHE) Industrial Associates Program has fruitfully completed its fourth year. Under the support of the AHE members and the joint effort of the research team, new and significant progress has been achieved in the year. Following the recommendations by the Advisory Task Force, the research effort is placed on more practical helicopter electromagnetic problems, such as HF antennas, composite materials, and antenna efficiencies. In this annual report, the main topics to be addressed include composite materials and antenna technology. The research work on each topic has been driven by the AHE consortium members' interests and needs. The remarkable achievements and progresses in each subject is reported respectively in individual sections of the report. The work in the area of composite materials includes: modeling of low conductivity composite materials by using Green's function approach; guidelines for composite material modeling by using the Green's function approach in the NEC code; development of 3-D volume mesh generator for modeling thick and volumetric dielectrics by using FD-TD method; modeling antenna elements mounted on a composite Comanche tail stabilizer; and antenna pattern control and efficiency estimate for a horn antenna loaded with composite dielectric materials.

  2. Advanced electromagnetic methods for aerospace vehicles

    NASA Technical Reports Server (NTRS)

    Balanis, Constantine A.; Sun, Weimin; El-Sharawy, El-Budawy; Aberle, James T.; Birtcher, Craig R.; Peng, Jian; Tirkas, Panayiotis A.; Kokotoff, David; Zavosh, Frank

    1993-01-01

    The Advanced Helicopter Electromagnetics (AHE) Industrial Associates Program has continuously progressed with its research effort focused on subjects identified and recommended by the Advisory Task Force of the program. The research activities in this reporting period have been steered toward practical helicopter electromagnetic problems, such as HF antenna problems and antenna efficiencies, recommended by the AHE members at the annual conference held at Arizona State University on 28-29 Oct. 1992 and the last biannual meeting held at the Boeing Helicopter on 19-20 May 1993. The main topics addressed include the following: Composite Materials and Antenna Technology. The research work on each topic is closely tied with the AHE Consortium members' interests. Significant progress in each subject is reported. Special attention in the area of Composite Materials has been given to the following: modeling of material discontinuity and their effects on towel-bar antenna patterns; guidelines for composite material modeling by using the Green's function approach in the NEC code; measurements of towel-bar antennas grounded with a partially material-coated plate; development of 3-D volume mesh generator for modeling thick and volumetric dielectrics by using FD-TD method; FDTD modeling of horn antennas with composite E-plane walls; and antenna efficiency analysis for a horn antenna loaded with composite dielectric materials.

  3. Computational and design methods for advanced imaging

    NASA Astrophysics Data System (ADS)

    Birch, Gabriel C.

    This dissertation merges the optical design and computational aspects of imaging systems to create novel devices that solve engineering problems in optical science and attempts to expand the solution space available to the optical designer. This dissertation is divided into two parts: the first discusses a new active illumination depth sensing modality, while the second part discusses a passive illumination system called plenoptic, or lightfield, imaging. The new depth sensing modality introduced in part one is called depth through controlled aberration. This technique illuminates a target with a known, aberrated projected pattern and takes an image using a traditional, unmodified imaging system. Knowing how the added aberration in the projected pattern changes as a function of depth, we are able to quantitatively determine depth of a series of points from the camera. A major advantage this method permits is the ability for illumination and imaging axes to be coincident. Plenoptic cameras capture both spatial and angular data simultaneously. This dissertation present a new set of parameters that permit the design and comparison of plenoptic devices outside the traditionally published plenoptic 1.0 and plenoptic 2.0 configurations. Additionally, a series of engineering advancements are presented, including full system raytraces of raw plenoptic images, Zernike compression techniques of raw image files, and non-uniform lenslet arrays to compensate for plenoptic system aberrations. Finally, a new snapshot imaging spectrometer is proposed based off the plenoptic configuration.

  4. Alternative method for measuring effective focal length of lenses using the front and back surface reflections from a reference plate.

    PubMed

    Kim, Do-Hyun; Shi, Dexiu; Ilev, Ilko K

    2011-09-10

    We present a simple method for measuring the effective focal length without determining the location of principle plane of the lens. The method is based on the measurement of confocal backreflection axial responses from the front and back surfaces of a reference plate with known refractive index and thickness. We proved the concept by measuring the effective focal lengths of thin singlet lenses and complex microscope objectives. The theoretical limit of measurement precision varies depending on the numerical aperture of the lens. This method can provide an alternative focal length measurement method for complex lenses or lenses that are permanently attached to other structures. Measurement errors were analyzed theoretically and improvements in measurement accuracy were discussed.

  5. An accuracy analysis of the front tracking method and interface capturing methods for the solution of heat transfer problems with phase changes

    NASA Astrophysics Data System (ADS)

    Klimeš, Lubomír; Mauder, Tomáš; Charvát, Pavel; Štétina, Josef

    2016-09-01

    Materials undergoing a phase change have a number of applications in practice and engineering. Computer simulation tools are often used for investigation of such heat transfer problems with phase changes since they are fast and relatively not expensive. However, a crucial issue is the accuracy of these simulation tools. Numerical methods from the interface capturing category are frequently applied. Such approaches, however, allow for only approximate tracking of the interface between the phases. The paper presents an accuracy analysis and comparison of two widely used interface capturing methods—the enthalpy and the effective heat capacity methods—with the front tracking algorithm. A paraffin-based phase change material is assumed in the study. Computational results show that the front tracking algorithm provides a significantly higher accuracy level than the considered interface capturing methods.

  6. Development of a Front Tracking Method for Two-Phase Micromixing of Incompressible Viscous Fluids with Interfacial Tension in Solvent Extraction

    SciTech Connect

    Zhou, Yijie; Lim, Hyun-Kyung; de Almeida, Valmor F; Navamita, Ray; Wang, Shuqiang; Glimm, James G; Li, Xiao-lin; Jiao, Xiangmin

    2012-06-01

    This progress report describes the development of a front tracking method for the solution of the governing equations of motion for two-phase micromixing of incompressible, viscous, liquid-liquid solvent extraction processes. The ability to compute the detailed local interfacial structure of the mixture allows characterization of the statistical properties of the two-phase mixture in terms of droplets, filaments, and other structures which emerge as a dispersed phase embedded into a continuous phase. Such a statistical picture provides the information needed for building a consistent coarsened model applicable to the entire mixing device. Coarsening is an undertaking for a future mathematical development and is outside the scope of the present work. We present here a method for accurate simulation of the micromixing dynamics of an aqueous and an organic phase exposed to intense centrifugal force and shearing stress. The onset of mixing is the result of the combination of the classical Rayleigh- Taylor and Kelvin-Helmholtz instabilities. A mixing environment that emulates a sector of the annular mixing zone of a centrifugal contactor is used for the mathematical domain. The domain is small enough to allow for resolution of the individual interfacial structures and large enough to allow for an analysis of their statistical distribution of sizes and shapes. A set of accurate algorithms for this application requires an advanced front tracking approach constrained by the incompressibility condition. This research is aimed at designing and implementing these algorithms. We demonstrate verification and convergence results for one-phase and unmixed, two-phase flows. In addition we report on preliminary results for mixed, two-phase flow for realistic operating flow parameters.

  7. Advanced Source Deconvolution Methods for Compton Telescopes

    NASA Astrophysics Data System (ADS)

    Zoglauer, Andreas

    The next generation of space telescopes utilizing Compton scattering for astrophysical observations is destined to one day unravel the mysteries behind Galactic nucleosynthesis, to determine the origin of the positron annihilation excess near the Galactic center, and to uncover the hidden emission mechanisms behind gamma-ray bursts. Besides astrophysics, Compton telescopes are establishing themselves in heliophysics, planetary sciences, medical imaging, accelerator physics, and environmental monitoring. Since the COMPTEL days, great advances in the achievable energy and position resolution were possible, creating an extremely vast, but also extremely sparsely sampled data space. Unfortunately, the optimum way to analyze the data from the next generation of Compton telescopes has not yet been found, which can retrieve all source parameters (location, spectrum, polarization, flux) and achieves the best possible resolution and sensitivity at the same time. This is especially important for all sciences objectives looking at the inner Galaxy: the large amount of expected sources, the high background (internal and Galactic diffuse emission), and the limited angular resolution, make it the most taxing case for data analysis. In general, two key challenges exist: First, what are the best data space representations to answer the specific science questions? Second, what is the best way to deconvolve the data to fully retrieve the source parameters? For modern Compton telescopes, the existing data space representations can either correctly reconstruct the absolute flux (binned mode) or achieve the best possible resolution (list-mode), both together were not possible up to now. Here we propose to develop a two-stage hybrid reconstruction method which combines the best aspects of both. Using a proof-of-concept implementation we can for the first time show that it is possible to alternate during each deconvolution step between a binned-mode approach to get the flux right and a

  8. [The Study of Advanced Fundamental Parameter Method in EDXRFA].

    PubMed

    Cheng, Feng; Zhang, Qing-xian; Ge, Liang-quan; Gu, Yi; Zeng, Guo-qiang; Luo, Yao-yao; Chen, Shuang; Wang, Lei; Zhao, Jian-kun

    2015-07-01

    The X-ray Fluorescence Analysis(XRFA) is an important and efficient method on the element anylsis and is used in geology, industry and environment protection. But XRFA has a backdraw that the determination limit and accuracy are effected by the matrix of the sample. Now the fundamental parameter is usually used to calculate the content of elements in XRFA, and it is an efficient method if the matrix and net area of characteristic X-ray peak are obtained. But this is invalide in in-stu XRFA. Also the method of net area and the "black material" of sample are the key point of the fundamental parameter method when the Energy Dispersive X-ray Fluorescence Analysis(EDXRFA) method is used in the low content sample. In this paper a advanced fundamental parameter method is discussed. The advanced fundamental parameter method includes the spectra analysis and the fundamental parameter method, which inserts the overlapping peaks separation method into the iteration process of the fundamental parameter method. The advanced method can resolve the net area and the quantitative analysis. The advanced method is used to analyse the standard sample. Compare to the content obtained from the coefficient method, the precision of Cu, Ni and Zn is better than coeffieciency method. The result shows that the advanced method could improve the precision of the EDXRFA, so the advanced method is better than the coefficient method.

  9. The Applicability of Modern Front-Capturing Methods to the Modeling of Small-Amplitude Instability Growth

    NASA Astrophysics Data System (ADS)

    Zalesak, Steven T.

    2003-10-01

    Modern front-capturing methods, such as flux-corrected transport (FCT) methods, total variation diminishing (TVD) methods, and high order Godunov methods (e.g., MUSCL, PPM, ENO, WENO, and discontinuous Galerkin methods), were developed to address the numerical difficulties that one encounters when attempting to solve problems where discontinuities or near-discontinuities are expected to form in the quantities being modeled, or in one or more of their derivatives. Such methods are usually described as being inherently ``nonlinear.'' While true, this statement does not adequately describe the nature of such methods, for they are often not even differentiable with respect to small perturbations in the solution. This is not usually a problem for stable flows, but when the flows of interest are unstable, and when one is interested in the evolution of small perturbations to those flows, the use of such numerical methods would appear to be quite risky. We describe experiments we have conducted investigating such methods, and some alternatives to such methods, in the context of evolving Rayleigh-Taylor and Richtmyer-Meshkov instabilities.

  10. Non-Contact Methods for Measuring Front Cavity Depths of Laboratory Standard Microphones Using a Depth-Measuring Microscope

    PubMed Central

    Nedzelnitsky, Victor; Wagner, Randall P.

    2008-01-01

    To achieve an acceptable degree of accuracy at high frequencies in some standardized methods for primary calibration of laboratory standard (LS) microphones, the front cavity depth lfc of each microphone must be known. This dimension must be measured using non-contact methods to prevent damage to the microphone diaphragm. The basic capabilities of an optical depth-measuring microscope were demonstrated by the agreement of its measurements within 0.7 μm of the known values of reference gage blocks. Using this microscope, two basic methods were applied to measure lfc. One (D) uses direct measurements at the microphone front surface annulus and conventional data reduction techniques. The other (GB) uses measurements at the surface of a gage block placed on the annulus, and plane-fitting data reduction techniques intended to reduce the effects of the slightly imperfect geometries of the microphones. The GB method was developed to provide a smoother surface of measurement than the relatively rough surface of the annulus, and to simulate the contact that occurs between the annulus and the smooth, plane surface of an acoustic coupler during microphone calibration. Using these methods, full data sets were obtained at 33 measurement positions (D), or 25 positions (GB). In addition, D and GB subsampling methods were applied by using subsamples of either the D or the GB full data sets. All these methods were applied to six LS microphones, three each of two different types. The GB subsampling methods are preferred for several reasons. The measurement results for lfc obtained by these methods agree well with those obtained by the GB method using the full data set. The expanded uncertainties of results from the GB subsampling methods are not very different from the expanded uncertainty of results from the GB method using the full data set, and are smaller than the expanded uncertainties of results from the D subsampling methods. Measurements of lfc using the GB subsampling

  11. Advanced electromagnetic methods for aerospace vehicles

    NASA Technical Reports Server (NTRS)

    Balanis, Constantine A.; Sun, Weimin; El-Sharawy, El-Budawy; Aberle, James T.; Birtcher, Craig R.; Peng, Jian; Tirkas, Panayiotis A.

    1992-01-01

    The Advanced Helicopter Electromagnetics (AHE) Industrial Associates Program continues its research on variety of main topics identified and recommended by the Advisory Task Force of the program. The research activities center on issues that advance technology related to helicopter electromagnetics. While most of the topics are a continuation of previous works, special effort has been focused on some of the areas due to recommendations from the last annual conference. The main topics addressed in this report are: composite materials, and antenna technology. The area of composite materials continues getting special attention in this period. The research has focused on: (1) measurements of the electrical properties of low-conductivity materials; (2) modeling of material discontinuity and their effects on the scattering patterns; (3) preliminary analysis on interaction of electromagnetic fields with multi-layered graphite fiberglass plates; and (4) finite difference time domain (FDTD) modeling of fields penetration through composite panels of a helicopter.

  12. Controlling template erosion with advanced cleaning methods

    NASA Astrophysics Data System (ADS)

    Singh, SherJang; Yu, Zhaoning; Wähler, Tobias; Kurataka, Nobuo; Gauzner, Gene; Wang, Hongying; Yang, Henry; Hsu, Yautzong; Lee, Kim; Kuo, David; Dress, Peter

    2012-03-01

    We studied the erosion and feature stability of fused silica patterns under different template cleaning conditions. The conventional SPM cleaning is compared with an advanced non-acid process. Spectroscopic ellipsometry optical critical dimension (SE-OCD) measurements were used to characterize the changes in pattern profile with good sensitivity. This study confirmed the erosion of the silica patterns in the traditional acid-based SPM cleaning mixture (H2SO4+H2O2) at a rate of ~0.1nm per cleaning cycle. The advanced non-acid clean process however only showed CD shift of ~0.01nm per clean. Contamination removal & pattern integrity of sensitive 20nm features under MegaSonic assisted cleaning is also demonstrated.

  13. Advanced methods of structural and trajectory analysis for transport aircraft

    NASA Technical Reports Server (NTRS)

    Ardema, Mark D.

    1995-01-01

    This report summarizes the efforts in two areas: (1) development of advanced methods of structural weight estimation, and (2) development of advanced methods of trajectory optimization. The majority of the effort was spent in the structural weight area. A draft of 'Analytical Fuselage and Wing Weight Estimation of Transport Aircraft', resulting from this research, is included as an appendix.

  14. Time resolved small angle X-ray scattering experiments performed on detonating explosives at the advanced photon source: Calculation of the time and distance between the detonation front and the x-ray beam

    NASA Astrophysics Data System (ADS)

    Gustavsen, R. L.; Dattelbaum, D. M.; Watkins, E. B.; Firestone, M. A.; Podlesak, D. W.; Jensen, B. J.; Ringstrand, B. S.; Huber, R. C.; Mang, J. T.; Johnson, C. E.; Velizhanin, K. A.; Willey, T. M.; Hansen, D. W.; May, C. M.; Hodgin, R. L.; Bagge-Hansen, M.; van Buuren, A. W.; Lauderbach, L. M.; Jones, A. C.; Graber, T. J.; Sinclair, N.; Seifert, S.; Gog, T.

    2017-03-01

    Time resolved Small Angle X-ray Scattering (SAXS) experiments on detonating explosives have been conducted at Argonne National Laboratory's Advanced Photon Source Dynamic Compression Sector. The purpose of the experiments is to measure the SAXS patterns at tens of ns to a few μs behind the detonation front. Corresponding positions behind the detonation front are of order 0.1-10 mm. From the scattering patterns, properties of the explosive products relative to the time behind the detonation front can be inferred. This report describes how the time and distance from the x-ray probe location to the detonation front is calculated, as well as the uncertainties and sources of uncertainty associated with the calculated times and distances.

  15. Unconstrained paving and plastering method for generating finite element meshes

    DOEpatents

    Staten, Matthew L.; Owen, Steven J.; Blacker, Teddy D.; Kerr, Robert

    2010-03-02

    Computer software for and a method of generating a conformal all quadrilateral or hexahedral mesh comprising selecting an object with unmeshed boundaries and performing the following while unmeshed voids are larger than twice a desired element size and unrecognizable as either a midpoint subdividable or pave-and-sweepable polyhedra: selecting a front to advance; based on sizes of fronts and angles with adjacent fronts, determining which adjacent fronts should be advanced with the selected front; advancing the fronts; detecting proximities with other nearby fronts; resolving any found proximities; forming quadrilaterals or unconstrained columns of hexahedra where two layers cross; and establishing hexahedral elements where three layers cross.

  16. Advanced electromagnetic methods for aerospace vehicles

    NASA Technical Reports Server (NTRS)

    Balanis, Constantine A.; El-Sharawy, El-Budawy; Hashemi-Yeganeh, Shahrokh; Aberle, James T.; Birtcher, Craig R.

    1991-01-01

    The Advanced Helicopter Electromagnetics is centered on issues that advance technology related to helicopter electromagnetics. Progress was made on three major topics: composite materials; precipitation static corona discharge; and antenna technology. In composite materials, the research has focused on the measurements of their electrical properties, and the modeling of material discontinuities and their effect on the radiation pattern of antennas mounted on or near material surfaces. The electrical properties were used to model antenna performance when mounted on composite materials. Since helicopter platforms include several antenna systems at VHF and UHF bands, measuring techniques are being explored that can be used to measure the properties at these bands. The effort on corona discharge and precipitation static was directed toward the development of a new two dimensional Voltage Finite Difference Time Domain computer program. Results indicate the feasibility of using potentials for simulating electromagnetic problems in the cases where potentials become primary sources. In antenna technology the focus was on Polarization Diverse Conformal Microstrip Antennas, Cavity Backed Slot Antennas, and Varactor Tuned Circular Patch Antennas. Numerical codes were developed for the analysis of two probe fed rectangular and circular microstrip patch antennas fed by resistive and reactive power divider networks.

  17. Geomatic methods applied to the study of the front position changes of Johnsons and Hurd Glaciers, Livingston Island, Antarctica, between 1957 and 2013

    NASA Astrophysics Data System (ADS)

    Rodríguez Cielos, Ricardo; Aguirre de Mata, Julián; Díez Galilea, Andrés; Álvarez Alonso, Marina; Rodríguez Cielos, Pedro; Navarro Valero, Francisco

    2016-08-01

    Various geomatic measurement techniques can be efficiently combined for surveying glacier fronts. Aerial photographs and satellite images can be used to determine the position of the glacier terminus. If the glacier front is easily accessible, the classic surveys using theodolite or total station, GNSS (Global Navigation Satellite System) techniques, laser-scanner or close-range photogrammetry are possible. When the accessibility to the glacier front is difficult or impossible, close-range photogrammetry proves to be useful, inexpensive and fast. In this paper, a methodology combining photogrammetric methods and other techniques is applied to determine the calving front position of Johnsons Glacier. Images taken in 2013 with an inexpensive nonmetric digital camera are georeferenced to a global coordinate system by measuring, using GNSS techniques, support points in accessible areas close to the glacier front, from which control points in inaccessible points on the glacier surface near its calving front are determined with theodolite using the direct intersection method. The front position changes of Johnsons Glacier during the period 1957-2013, as well as those of the land-terminating fronts of Argentina, Las Palmas and Sally Rocks lobes of Hurd glacier, are determined from different geomatic techniques such as surface-based GNSS measurements, aerial photogrammetry and satellite optical imagery. This provides a set of frontal positions useful, e.g., for glacier dynamics modeling and mass balance studies.Link to the data repository: https://doi.pangaea.de/10.1594/PANGAEA.845379.

  18. A 3D front tracking method on a CPU/GPU system

    SciTech Connect

    Bo, Wurigen; Grove, John

    2011-01-21

    We describe the method to port a sequential 3D interface tracking code to a GPU with CUDA. The interface is represented as a triangular mesh. Interface geometry properties and point propagation are performed on a GPU. Interface mesh adaptation is performed on a CPU. The convergence of the method is assessed from the test problems with given velocity fields. Performance results show overall speedups from 11 to 14 for the test problems under mesh refinement. We also briefly describe our ongoing work to couple the interface tracking method with a hydro solver.

  19. Advanced particulate matter control apparatus and methods

    DOEpatents

    Miller, Stanley J [Grand Forks, ND; Zhuang, Ye [Grand Forks, ND; Almlie, Jay C [East Grand Forks, MN

    2012-01-10

    Apparatus and methods for collection and removal of particulate matter, including fine particulate matter, from a gas stream, comprising a unique combination of high collection efficiency and ultralow pressure drop across the filter. The apparatus and method utilize simultaneous electrostatic precipitation and membrane filtration of a particular pore size, wherein electrostatic collection and filtration occur on the same surface.

  20. Advanced reliability methods for structural evaluation

    NASA Technical Reports Server (NTRS)

    Wirsching, P. H.; Wu, Y.-T.

    1985-01-01

    Fast probability integration (FPI) methods, which can yield approximate solutions to such general structural reliability problems as the computation of the probabilities of complicated functions of random variables, are known to require one-tenth the computer time of Monte Carlo methods for a probability level of 0.001; lower probabilities yield even more dramatic differences. A strategy is presented in which a computer routine is run k times with selected perturbed values of the variables to obtain k solutions for a response variable Y. An approximating polynomial is fit to the k 'data' sets, and FPI methods are employed for this explicit form.

  1. Indentation Methods in Advanced Materials Research Introduction

    SciTech Connect

    Pharr, George Mathews; Cheng, Yang-Tse; Hutchings, Ian; Sakai, Mototsugu; Moody, Neville; Sundararajan, G.; Swain, Michael V.

    2009-01-01

    Since its commercialization early in the 20th century, indentation testing has played a key role in the development of new materials and understanding their mechanical behavior. Progr3ess in the field has relied on a close marriage between research in the mechanical behavior of materials and contact mechanics. The seminal work of Hertz laid the foundations for bringing these two together, with his contributions still widely utilized today in examining elastic behavior and the physics of fracture. Later, the pioneering work of Tabor, as published in his classic text 'The Hardness of Metals', exapdned this understanding to address the complexities of plasticity. Enormous progress in the field has been achieved in the last decade, made possible both by advances in instrumentation, for example, load and depth-sensing indentation and scanning electron microscopy (SEM) and transmission electron microscopy (TEM) based in situ testing, as well as improved modeling capabilities that use computationally intensive techniques such as finite element analysis and molecular dynamics simulation. The purpose of this special focus issue is to present recent state of the art developments in the field.

  2. Advanced spectral methods for climatic time series

    USGS Publications Warehouse

    Ghil, M.; Allen, M.R.; Dettinger, M.D.; Ide, K.; Kondrashov, D.; Mann, M.E.; Robertson, A.W.; Saunders, A.; Tian, Y.; Varadi, F.; Yiou, P.

    2002-01-01

    The analysis of univariate or multivariate time series provides crucial information to describe, understand, and predict climatic variability. The discovery and implementation of a number of novel methods for extracting useful information from time series has recently revitalized this classical field of study. Considerable progress has also been made in interpreting the information so obtained in terms of dynamical systems theory. In this review we describe the connections between time series analysis and nonlinear dynamics, discuss signal- to-noise enhancement, and present some of the novel methods for spectral analysis. The various steps, as well as the advantages and disadvantages of these methods, are illustrated by their application to an important climatic time series, the Southern Oscillation Index. This index captures major features of interannual climate variability and is used extensively in its prediction. Regional and global sea surface temperature data sets are used to illustrate multivariate spectral methods. Open questions and further prospects conclude the review.

  3. Numerical simulation of drop impact on a liquid-liquid interface with a multiple marker front-capturing method

    NASA Astrophysics Data System (ADS)

    Coyajee, Emil; Boersma, Bendiks Jan

    2009-07-01

    The gravity-driven motion of a droplet impacting on a liquid-liquid interface is studied. The full Navier-Stokes equations are solved on a fixed, uniform grid using a finite difference/front-capturing method. For the representation of fluid-fluid interfaces, a coupled Level-Set/Volume-Of-Fluid method [M. Sussman, E.G. Puckett, A coupled Level-Set and Volume-of-Fluid method for computing 3D and axisymmetric incompressible two-phase flows, J. Comp. Phys. 162 (2000) 301-337] is used, in which we introduce the novel approach of describing separate interfaces with different marker functions. As a consequence, we prevent numerical coalescence of the droplet and the liquid-liquid interface without excessive (local) grid refinement. To validate our method, numerical simulations of the drop impact event are compared with experiments [Z. Mohamed-Kassim, E.K. Longmire, Drop impact on a liquid-liquid interface, Phys. Fluids 15 (2003) 3263-3273]. Furthermore, a comparison is made with the numerical results of [A. Esmaeeli, G. Tryggvason, Direct numerical simulations of bubbly flows. Part 2. Moderate Reynolds number arrays, J. Fluid Mech. 385 (1999) 325-358] for an array of rising bubbles. The investigation shows that the multiple marker approach successfully prevents numerical coalescence of interfaces and adequately captures the effect of surface tension.

  4. Method of up-front load balancing for local memory parallel processors

    NASA Technical Reports Server (NTRS)

    Baffes, Paul Thomas (Inventor)

    1990-01-01

    In a parallel processing computer system with multiple processing units and shared memory, a method is disclosed for uniformly balancing the aggregate computational load in, and utilizing minimal memory by, a network having identical computations to be executed at each connection therein. Read-only and read-write memory are subdivided into a plurality of process sets, which function like artificial processing units. Said plurality of process sets is iteratively merged and reduced to the number of processing units without exceeding the balance load. Said merger is based upon the value of a partition threshold, which is a measure of the memory utilization. The turnaround time and memory savings of the instant method are functions of the number of processing units available and the number of partitions into which the memory is subdivided. Typical results of the preferred embodiment yielded memory savings of from sixty to seventy five percent.

  5. A discontinuous Galerkin front tracking method for two-phase flows with surface tension

    SciTech Connect

    Nguyen, V.-T.; Peraire, J.; Cheong, K.B.; Persson, P.-O.

    2008-12-28

    A Discontinuous Galerkin method for solving hyperbolic systems of conservation laws involving interfaces is presented. The interfaces are represented by a collection of element boundaries and their position is updated using an arbitrary Lagrangian-Eulerian method. The motion of the interfaces and the numerical fluxes are obtained by solving a Riemann problem. As the interface is propagated, a simple and effective remeshing technique based on distance functions regenerates the grid to preserve its quality. Compared to other interface capturing techniques, the proposed approach avoids smearing of the jumps across the interface which leads to an improvement in accuracy. Numerical results are presented for several typical two-dimensional interface problems, including flows with surface tension.

  6. Advances in Geometric Acoustic Propagation Modeling Methods

    NASA Astrophysics Data System (ADS)

    Blom, P. S.; Arrowsmith, S.

    2013-12-01

    Geometric acoustics provides an efficient numerical method to model propagation effects. At leading order, one can identify ensonified regions and calculate celerities of the predicted arrivals. Beyond leading order, the solution of the transport equation provides a means to estimate the amplitude of individual acoustic phases. The auxiliary parameters introduced in solving the transport equation have been found to provide a means of identifying ray paths connecting source and receiver, or eigenrays, for non-planar propagation. A detailed explanation of the eigenray method will be presented as well as an application to predicting azimuth deviations for infrasonic data recorded during the Humming Roadrunner experiment of 2012.

  7. Advanced method for making vitreous waste forms

    SciTech Connect

    Pope, J.M.; Harrison, D.E.

    1980-01-01

    A process is described for making waste glass that circumvents the problems of dissolving nuclear waste in molten glass at high temperatures. Because the reactive mixing process is independent of the inherent viscosity of the melt, any glass composition can be prepared with equal facility. Separation of the mixing and melting operations permits novel glass fabrication methods to be employed.

  8. Advanced methods in synthetic aperture radar imaging

    NASA Astrophysics Data System (ADS)

    Kragh, Thomas

    2012-02-01

    For over 50 years our world has been mapped and measured with synthetic aperture radar (SAR). A SAR system operates by transmitting a series of wideband radio-frequency pulses towards the ground and recording the resulting backscattered electromagnetic waves as the system travels along some one-dimensional trajectory. By coherently processing the recorded backscatter over this extended aperture, one can form a high-resolution 2D intensity map of the ground reflectivity, which we call a SAR image. The trajectory, or synthetic aperture, is achieved by mounting the radar on an aircraft, spacecraft, or even on the roof of a car traveling down the road, and allows for a diverse set of applications and measurement techniques for remote sensing applications. It is quite remarkable that the sub-centimeter positioning precision and sub-nanosecond timing precision required to make this work properly can in fact be achieved under such real-world, often turbulent, vibrationally intensive conditions. Although the basic principles behind SAR imaging and interferometry have been known for decades, in recent years an explosion of data exploitation techniques enabled by ever-faster computational horsepower have enabled some remarkable advances. Although SAR images are often viewed as simple intensity maps of ground reflectivity, SAR is also an exquisitely sensitive coherent imaging modality with a wealth of information buried within the phase information in the image. Some of the examples featured in this presentation will include: (1) Interferometric SAR, where by comparing the difference in phase between two SAR images one can measure subtle changes in ground topography at the wavelength scale. (2) Change detection, in which carefully geolocated images formed from two different passes are compared. (3) Multi-pass 3D SAR tomography, where multiple trajectories can be used to form 3D images. (4) Moving Target Indication (MTI), in which Doppler effects allow one to detect and

  9. Advanced Electromagnetic Methods for Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Balanis, Constantine A.; Polycarpou, Anastasis; Birtcher, Craig R.; Georgakopoulos, Stavros; Han, Dong-Ho; Ballas, Gerasimos

    1999-01-01

    The imminent destructive threats of Lightning on helicopters and other airborne systems has always been a topic of great interest to this research grant. Previously, the lightning induced currents on the surface of the fuselage and its interior were predicted using the finite-difference time-domain (FDTD) method as well as the NEC code. The limitations of both methods, as applied to lightning, were identified and extensively discussed in the last meeting. After a thorough investigation of the capabilities of the FDTD, it was decided to incorporate into the numerical method a subcell model to accurately represent current diffusion through conducting materials of high conductivity and finite thickness. Because of the complexity of the model, its validity will be first tested for a one-dimensional FDTD problem. Although results are not available yet, the theory and formulation of the subcell model are presented and discussed here to a certain degree. Besides lightning induced currents in the interior of an aircraft, penetration of electromagnetic fields through apertures (e.g., windows and cracks) could also be devastating for the navigation equipment, electronics, and communications systems in general. The main focus of this study is understanding and quantifying field penetration through apertures. The simulation is done using the FDTD method and the predictions are compared with measurements and moment method solutions obtained from the NASA Langley Research Center. Cavity-backed slot (CBS) antennas or slot antennas in general have many applications in aircraft-satellite type of communications. These can be flushmounted on the surface of the fuselage and, therefore, they retain the aerodynamic shape of the aircraft. In the past, input impedance and radiation patterns of CBS antennas were computed using a hybrid FEM/MoM code. The analysis is now extended to coupling between two identical slot antennas mounted on the same structure. The predictions are performed

  10. Cost estimating methods for advanced space systems

    NASA Technical Reports Server (NTRS)

    Cyr, Kelley

    1988-01-01

    Parametric cost estimating methods for space systems in the conceptual design phase are developed. The approach is to identify variables that drive cost such as weight, quantity, development culture, design inheritance, and time. The relationship between weight and cost is examined in detail. A theoretical model of cost is developed and tested statistically against a historical data base of major research and development programs. It is concluded that the technique presented is sound, but that it must be refined in order to produce acceptable cost estimates.

  11. Advancements in Research Synthesis Methods: From a Methodologically Inclusive Perspective

    ERIC Educational Resources Information Center

    Suri, Harsh; Clarke, David

    2009-01-01

    The dominant literature on research synthesis methods has positivist and neo-positivist origins. In recent years, the landscape of research synthesis methods has changed rapidly to become inclusive. This article highlights methodologically inclusive advancements in research synthesis methods. Attention is drawn to insights from interpretive,…

  12. Integrated chassis control of active front steering and yaw stability control based on improved inverse nyquist array method.

    PubMed

    Zhu, Bing; Chen, Yizhou; Zhao, Jian

    2014-01-01

    An integrated chassis control (ICC) system with active front steering (AFS) and yaw stability control (YSC) is introduced in this paper. The proposed ICC algorithm uses the improved Inverse Nyquist Array (INA) method based on a 2-degree-of-freedom (DOF) planar vehicle reference model to decouple the plant dynamics under different frequency bands, and the change of velocity and cornering stiffness were considered to calculate the analytical solution in the precompensator design so that the INA based algorithm runs well and fast on the nonlinear vehicle system. The stability of the system is guaranteed by dynamic compensator together with a proposed PI feedback controller. After the response analysis of the system on frequency domain and time domain, simulations under step steering maneuver were carried out using a 2-DOF vehicle model and a 14-DOF vehicle model by Matlab/Simulink. The results show that the system is decoupled and the vehicle handling and stability performance are significantly improved by the proposed method.

  13. Integrated Chassis Control of Active Front Steering and Yaw Stability Control Based on Improved Inverse Nyquist Array Method

    PubMed Central

    2014-01-01

    An integrated chassis control (ICC) system with active front steering (AFS) and yaw stability control (YSC) is introduced in this paper. The proposed ICC algorithm uses the improved Inverse Nyquist Array (INA) method based on a 2-degree-of-freedom (DOF) planar vehicle reference model to decouple the plant dynamics under different frequency bands, and the change of velocity and cornering stiffness were considered to calculate the analytical solution in the precompensator design so that the INA based algorithm runs well and fast on the nonlinear vehicle system. The stability of the system is guaranteed by dynamic compensator together with a proposed PI feedback controller. After the response analysis of the system on frequency domain and time domain, simulations under step steering maneuver were carried out using a 2-DOF vehicle model and a 14-DOF vehicle model by Matlab/Simulink. The results show that the system is decoupled and the vehicle handling and stability performance are significantly improved by the proposed method. PMID:24782676

  14. Current methods and advances in bone densitometry

    NASA Technical Reports Server (NTRS)

    Guglielmi, G.; Gluer, C. C.; Majumdar, S.; Blunt, B. A.; Genant, H. K.

    1995-01-01

    Bone mass is the primary, although not the only, determinant of fracture. Over the past few years a number of noninvasive techniques have been developed to more sensitively quantitate bone mass. These include single and dual photon absorptiometry (SPA and DPA), single and dual X-ray absorptiometry (SXA and DXA) and quantitative computed tomography (QCT). While differing in anatomic sites measured and in their estimates of precision, accuracy, and fracture discrimination, all of these methods provide clinically useful measurements of skeletal status. It is the intent of this review to discuss the pros and cons of these techniques and to present the new applications of ultrasound (US) and magnetic resonance (MRI) in the detection and management of osteoporosis.

  15. Advanced Fuzzy Potential Field Method for Mobile Robot Obstacle Avoidance

    PubMed Central

    Park, Jong-Wook; Kwak, Hwan-Joo; Kang, Young-Chang; Kim, Dong W.

    2016-01-01

    An advanced fuzzy potential field method for mobile robot obstacle avoidance is proposed. The potential field method primarily deals with the repulsive forces surrounding obstacles, while fuzzy control logic focuses on fuzzy rules that handle linguistic variables and describe the knowledge of experts. The design of a fuzzy controller—advanced fuzzy potential field method (AFPFM)—that models and enhances the conventional potential field method is proposed and discussed. This study also examines the rule-explosion problem of conventional fuzzy logic and assesses the performance of our proposed AFPFM through simulations carried out using a mobile robot. PMID:27123001

  16. Advanced Fuzzy Potential Field Method for Mobile Robot Obstacle Avoidance.

    PubMed

    Park, Jong-Wook; Kwak, Hwan-Joo; Kang, Young-Chang; Kim, Dong W

    2016-01-01

    An advanced fuzzy potential field method for mobile robot obstacle avoidance is proposed. The potential field method primarily deals with the repulsive forces surrounding obstacles, while fuzzy control logic focuses on fuzzy rules that handle linguistic variables and describe the knowledge of experts. The design of a fuzzy controller--advanced fuzzy potential field method (AFPFM)--that models and enhances the conventional potential field method is proposed and discussed. This study also examines the rule-explosion problem of conventional fuzzy logic and assesses the performance of our proposed AFPFM through simulations carried out using a mobile robot.

  17. Cost estimating methods for advanced space systems

    NASA Technical Reports Server (NTRS)

    Cyr, Kelley

    1994-01-01

    NASA is responsible for developing much of the nation's future space technology. Cost estimates for new programs are required early in the planning process so that decisions can be made accurately. Because of the long lead times required to develop space hardware, the cost estimates are frequently required 10 to 15 years before the program delivers hardware. The system design in conceptual phases of a program is usually only vaguely defined and the technology used is so often state-of-the-art or beyond. These factors combine to make cost estimating for conceptual programs very challenging. This paper describes an effort to develop parametric cost estimating methods for space systems in the conceptual design phase. The approach is to identify variables that drive cost such as weight, quantity, development culture, design inheritance and time. The nature of the relationships between the driver variables and cost will be discussed. In particular, the relationship between weight and cost will be examined in detail. A theoretical model of cost will be developed and tested statistically against a historical database of major research and development projects.

  18. Three-dimensional multi-relaxation-time lattice Boltzmann front-tracking method for two-phase flow

    NASA Astrophysics Data System (ADS)

    Hai-Qiong, Xie; Zhong, Zeng; Liang-Qi, Zhang

    2016-01-01

    We developed a three-dimensional multi-relaxation-time lattice Boltzmann method for incompressible and immiscible two-phase flow by coupling with a front-tracking technique. The flow field was simulated by using an Eulerian grid, an adaptive unstructured triangular Lagrangian grid was applied to track explicitly the motion of the two-fluid interface, and an indicator function was introduced to update accurately the fluid properties. The surface tension was computed directly on a triangular Lagrangian grid, and then the surface tension was distributed to the background Eulerian grid. Three benchmarks of two-phase flow, including the Laplace law for a stationary drop, the oscillation of a three-dimensional ellipsoidal drop, and the drop deformation in a shear flow, were simulated to validate the present model. Project supported by the National Natural Science Foundation of China (Grant No. 11572062), the Fundamental Research Funds for the Central Universities, China (Grant No. CDJZR13248801), the Program for Changjiang Scholars and Innovative Research Team in University, China (Grant No. IRT13043), and Key Laboratory of Functional Crystals and Laser Technology, TIPC, Chinese Academy of Sciences.

  19. Advanced Ablative Insulators and Methods of Making Them

    NASA Technical Reports Server (NTRS)

    Congdon, William M.

    2005-01-01

    Advanced ablative (more specifically, charring) materials that provide temporary protection against high temperatures, and advanced methods of designing and manufacturing insulators based on these materials, are undergoing development. These materials and methods were conceived in an effort to replace the traditional thermal-protection systems (TPSs) of re-entry spacecraft with robust, lightweight, better-performing TPSs that can be designed and manufactured more rapidly and at lower cost. These materials and methods could also be used to make improved TPSs for general aerospace, military, and industrial applications.

  20. Strategy to Promote Active Learning of an Advanced Research Method

    ERIC Educational Resources Information Center

    McDermott, Hilary J.; Dovey, Terence M.

    2013-01-01

    Research methods courses aim to equip students with the knowledge and skills required for research yet seldom include practical aspects of assessment. This reflective practitioner report describes and evaluates an innovative approach to teaching and assessing advanced qualitative research methods to final-year psychology undergraduate students. An…

  1. A Primer In Advanced Fatigue Life Prediction Methods

    NASA Technical Reports Server (NTRS)

    Halford, Gary R.

    2000-01-01

    Metal fatigue has plagued structural components for centuries, and it remains a critical durability issue in today's aerospace hardware. This is true despite vastly improved and advanced materials, increased mechanistic understanding, and development of accurate structural analysis and advanced fatigue life prediction tools. Each advance is quickly taken advantage of to produce safer, more reliable more cost effective, and better performing products. In other words, as the envelop is expanded, components are then designed to operate just as close to the newly expanded envelop as they were to the initial one. The problem is perennial. The economic importance of addressing structural durability issues early in the design process is emphasized. Tradeoffs with performance, cost, and legislated restrictions are pointed out. Several aspects of structural durability of advanced systems, advanced materials and advanced fatigue life prediction methods are presented. Specific items include the basic elements of durability analysis, conventional designs, barriers to be overcome for advanced systems, high-temperature life prediction for both creep-fatigue and thermomechanical fatigue, mean stress effects, multiaxial stress-strain states, and cumulative fatigue damage accumulation assessment.

  2. Numerical analysis of the jet stage of bubble near a solid wall using a front tracking method

    NASA Astrophysics Data System (ADS)

    Liu, L. T.; Yao, X. L.; Zhang, A. M.; Chen, Y. Y.

    2017-01-01

    The dynamics of a toroidal bubble near a solid wall for a large part of stand-off parameters γ (γ=d/Rmax, d is the distance between the solid wall and the bubble centre at the moment of formation and Rmax is the maximum bubble radius) have been extensively studied, but some mechanics of a toroidal bubble are not completely clear, especially for the small stand-off parameters γ ≤ 0.8. In the present study, on the basis of the finite volume method, the Navier-Stokes equations with inviscid and incompressible assumption are directly solved using a staggered grid on the fixed grid. The dynamics of the toroidal bubble near the solid for different stand-off parameters (γ = 0.4, 0.6, 0.8, and 0.97, respectively) are simulated by a front tracking method. Initial conditions of numerical simulation are estimated through the Rayleigh-Plesset equation, based on the maximum size and collapse time of a spark-generated bubble. One of the numerical results is compared with a spark-generated bubble experiment, showing that the results between them are favorable with regard to both the bubble shape history and translational motion of the bubble. The numerical results for the different stand-off parameters, including the change process of the water layer, the development process of the splash flow and radial flow, the splitting phenomenon of the toroidal bubble, and the trend of pressure on the center of the solid wall, are discussed, where some new phenomena are discovered.

  3. Advanced stress analysis methods applicable to turbine engine structures

    NASA Technical Reports Server (NTRS)

    Pian, T. H. H.

    1985-01-01

    Advanced stress analysis methods applicable to turbine engine structures are investigated. Constructions of special elements which containing traction-free circular boundaries are investigated. New versions of mixed variational principle and version of hybrid stress elements are formulated. A method is established for suppression of kinematic deformation modes. semiLoof plate and shell elements are constructed by assumed stress hybrid method. An elastic-plastic analysis is conducted by viscoplasticity theory using the mechanical subelement model.

  4. Advanced surface paneling method for subsonic and supersonic flow

    NASA Technical Reports Server (NTRS)

    Erickson, L. L.; Johnson, F. T.; Ehlers, F. E.

    1976-01-01

    Numerical results illustrating the capabilities of an advanced aerodynamic surface paneling method are presented. The method is applicable to both subsonic and supersonic flow, as represented by linearized potential flow theory. The method is based on linearly varying sources and quadratically varying doublets which are distributed over flat or curved panels. These panels are applied to the true surface geometry of arbitrarily shaped three dimensional aerodynamic configurations.

  5. Thermal Conductivity of Molten Silicate of Al2O3-CaO-Na2O-SiO2 Measured by Means of a Front Heating-Front Detection Laser Flash Method

    NASA Astrophysics Data System (ADS)

    Hasegawa, Hiroki; Kowatari, Takaya; Shiroki, Yasuhiro; Shibata, Hiroyuki; Ohta, Hiromichi; Waseda, Yoshio

    2012-12-01

    Thermal conductivity values have been systematically obtained for molten silicates containing Al2O3, CaO, Na2O, and SiO2 by means of a front heating-front detection laser flash method. The measurements were made for 13 samples in the temperature range between 1073 K and 1823 K (800 °C and 1550 °C), depending on the composition. Thermal conductivities of the silicate melts are found to be relatively insensitive to the variation of temperature, but they depend on the composition ratio, particularly the ratio of Non-Bridging Oxygen ions per Tetrahedrally coordinated cation—NBO/T. The thermal conductivity values decrease from 2.8 W/mK to 1.5 W/mK with the NBO/T value until it reaches about 1. Thermal conductivity values become constant for silicate melts with a higher value of NBO/T. It is known that the length of the silicate chain decreases with disconnection by the addition of alkaline earth cation or alkaline cation. The strong correlation between thermal conductivity and NBO/T is quite likely to suggest that silicate chain is a preferential path for heat transport in silicate melts.

  6. Advanced digital methods for solid propellant burning rate determination

    NASA Astrophysics Data System (ADS)

    Jones, Daniel A.

    The work presented here is a study of a digital method for determining the combustion bomb burning rate of a fuel-rich gas generator propellant sample using the ultrasonic pulse-echo technique. The advanced digital method, which places user defined limits on the search for the ultrasonic echo from the burning surface, is computationally faster than the previous cross correlation method, and is able to analyze data for this class of propellant that the previous cross correlation data reduction method could not. For the conditions investigated, the best fit burning rate law at 800 psi from the ultrasonic technique and advanced cross correlation method is within 3 percent of an independent analysis of the same data, and is within 5 percent of the best fit burning rate law found from parallel research of the same propellant in a motor configuration.

  7. 40 CFR 63.490 - Batch front-end process vents-performance test methods and procedures to determine compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Pollutant Emissions: Group I Polymers and Resins § 63.490 Batch front-end process vents—performance test... may be based on either total organic HAP or TOC. For purposes of this paragraph (c), the term “batch... inlet sampling sites shall ensure the measurement of total organic HAP or TOC (minus methane and...

  8. Advanced propulsion for LEO-Moon transport. 1: A method for evaluating advanced propulsion performance

    NASA Technical Reports Server (NTRS)

    Stern, Martin O.

    1992-01-01

    This report describes a study to evaluate the benefits of advanced propulsion technologies for transporting materials between low Earth orbit and the Moon. A relatively conventional reference transportation system, and several other systems, each of which includes one advanced technology component, are compared in terms of how well they perform a chosen mission objective. The evaluation method is based on a pairwise life-cycle cost comparison of each of the advanced systems with the reference system. Somewhat novel and economically important features of the procedure are the inclusion not only of mass payback ratios based on Earth launch costs, but also of repair and capital acquisition costs, and of adjustments in the latter to reflect the technological maturity of the advanced technologies. The required input information is developed by panels of experts. The overall scope and approach of the study are presented in the introduction. The bulk of the paper describes the evaluation method; the reference system and an advanced transportation system, including a spinning tether in an eccentric Earth orbit, are used to illustrate it.

  9. METHODS ADVANCEMENT FOR MILK ANALYSIS: THE MAMA STUDY

    EPA Science Inventory

    The Methods Advancement for Milk Analysis (MAMA) study was designed by US EPA and CDC investigators to provide data to support the technological and study design needs of the proposed National Children=s Study (NCS). The NCS is a multi-Agency-sponsored study, authorized under the...

  10. Advanced boundary layer transition measurement methods for flight applications

    NASA Technical Reports Server (NTRS)

    Holmes, B. J.; Croom, C. C.; Gail, P. D.; Manuel, G. S.; Carraway, D. L.

    1986-01-01

    In modern laminar flow flight research, it is important to understand the specific cause(s) of laminar to turbulent boundary-layer transition. Such information is crucial to the exploration of the limits of practical application of laminar flow for drag reduction on aircraft. The transition modes of interest in current flight investigations include the viscous Tollmien-Schlichting instability, the inflectional instability at laminar separation, and the crossflow inflectional instability, as well as others. This paper presents the results to date of research on advanced devices and methods used for the study of laminar boundary-layer transition phenomena in the flight environment. Recent advancements in the development of arrayed hot-film devices and of a new flow visualization method are discussed. Arrayed hot-film devices have been designed to detect the presence of laminar separation, and of crossflow vorticity. The advanced flow visualization method utilizes color changes in liquid-crystal coatings to detect boundary-layer transition at high altitude flight conditions. Flight and wind tunnel data are presented to illustrate the design and operation of these advanced methods. These new research tools provide information on disturbance growth and transition mode which is essential to furthering our understanding of practical design limits for applications of laminar flow technology.

  11. Advances and future directions of research on spectral methods

    NASA Technical Reports Server (NTRS)

    Patera, A. T.

    1986-01-01

    Recent advances in spectral methods are briefly reviewed and characterized with respect to their convergence and computational complexity. Classical finite element and spectral approaches are then compared, and spectral element (or p-type finite element) approximations are introduced. The method is applied to the full Navier-Stokes equations, and examples are given of the application of the technique to several transitional flows. Future directions of research in the field are outlined.

  12. An advanced Gibbs-Duhem integration method: theory and applications.

    PubMed

    van 't Hof, A; Peters, C J; de Leeuw, S W

    2006-02-07

    The conventional Gibbs-Duhem integration method is very convenient for the prediction of phase equilibria of both pure components and mixtures. However, it turns out to be inefficient. The method requires a number of lengthy simulations to predict the state conditions at which phase coexistence occurs. This number is not known from the outset of the numerical integration process. Furthermore, the molecular configurations generated during the simulations are merely used to predict the coexistence condition and not the liquid- and vapor-phase densities and mole fractions at coexistence. In this publication, an advanced Gibbs-Duhem integration method is presented that overcomes above-mentioned disadvantage and inefficiency. The advanced method is a combination of Gibbs-Duhem integration and multiple-histogram reweighting. Application of multiple-histogram reweighting enables the substitution of the unknown number of simulations by a fixed and predetermined number. The advanced method has a retroactive nature; a current simulation improves the predictions of previously computed coexistence points as well. The advanced Gibbs-Duhem integration method has been applied for the prediction of vapor-liquid equilibria of a number of binary mixtures. The method turned out to be very convenient, much faster than the conventional method, and provided smooth simulation results. As the employed force fields perfectly predict pure-component vapor-liquid equilibria, the binary simulations were very well suitable for testing the performance of different sets of combining rules. Employing Lorentz-Hudson-McCoubrey combining rules for interactions between unlike molecules, as opposed to Lorentz-Berthelot combining rules for all interactions, considerably improved the agreement between experimental and simulated data.

  13. Cloud Front

    NASA Technical Reports Server (NTRS)

    2006-01-01

    [figure removed for brevity, see original site] Context image for PIA02171 Cloud Front

    These clouds formed in the south polar region. The faintness of the cloud system likely indicates that these are mainly ice clouds, with relatively little dust content.

    Image information: VIS instrument. Latitude -86.7N, Longitude 212.3E. 17 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  14. Advances in nucleic acid-based detection methods.

    PubMed Central

    Wolcott, M J

    1992-01-01

    Laboratory techniques based on nucleic acid methods have increased in popularity over the last decade with clinical microbiologists and other laboratory scientists who are concerned with the diagnosis of infectious agents. This increase in popularity is a result primarily of advances made in nucleic acid amplification and detection techniques. Polymerase chain reaction, the original nucleic acid amplification technique, changed the way many people viewed and used nucleic acid techniques in clinical settings. After the potential of polymerase chain reaction became apparent, other methods of nucleic acid amplification and detection were developed. These alternative nucleic acid amplification methods may become serious contenders for application to routine laboratory analyses. This review presents some background information on nucleic acid analyses that might be used in clinical and anatomical laboratories and describes some recent advances in the amplification and detection of nucleic acids. PMID:1423216

  15. Evolution of a physical and biological front from upwelling to relaxation

    NASA Astrophysics Data System (ADS)

    Zhang, Yanwu; Bellingham, James G.; Ryan, John P.; Godin, Michael A.

    2015-10-01

    Fronts influence the structure and function of coastal marine ecosystems. Due to the complexity and dynamic nature of coastal environments and the small scales of frontal gradient zones, frontal research is difficult. To advance this challenging research we developed a method enabling an autonomous underwater vehicle (AUV) to detect and track fronts, thereby providing high-resolution observations in the moving reference frame of the front itself. This novel method was applied to studying the evolution of a frontal zone in the coastal upwelling environment of Monterey Bay, California, through a period of variability in upwelling intensity. Through 23 frontal crossings in four days, the AUV detected the front using real-time analysis of vertical thermal stratification to identify water types and the front between them, and the vehicle tracked the front as it moved more than 10 km offshore. The physical front coincided with a biological front between strongly stratified phytoplankton-enriched water inshore of the front, and weakly stratified phytoplankton-poor water offshore of the front. While stratification remained a consistent identifier, conditions on both sides of the front changed rapidly as regional circulation responded to relaxation of upwelling winds. The offshore water type transitioned from relatively cold and saline upwelled water to relatively warm and fresh coastal transition zone water. The inshore water type exhibited an order of magnitude increase in chlorophyll concentrations and an associated increase in oxygen and decrease in nitrate. It also warmed and freshened near the front, consistent with the cross-frontal exchange that was detected in the high-resolution AUV data. AUV-observed cross-frontal exchanges beneath the surface manifestation of the front emphasize the importance of AUV synoptic water column surveys in the frontal zone.

  16. Advanced Doubling Adding Method for Radiative Transfer in Planetary Atmospheres

    NASA Astrophysics Data System (ADS)

    Liu, Quanhua; Weng, Fuzhong

    2006-12-01

    The doubling adding method (DA) is one of the most accurate tools for detailed multiple-scattering calculations. The principle of the method goes back to the nineteenth century in a problem dealing with reflection and transmission by glass plates. Since then the doubling adding method has been widely used as a reference tool for other radiative transfer models. The method has never been used in operational applications owing to tremendous demand on computational resources from the model. This study derives an analytical expression replacing the most complicated thermal source terms in the doubling adding method. The new development is called the advanced doubling adding (ADA) method. Thanks also to the efficiency of matrix and vector manipulations in FORTRAN 90/95, the advanced doubling adding method is about 60 times faster than the doubling adding method. The radiance (i.e., forward) computation code of ADA is easily translated into tangent linear and adjoint codes for radiance gradient calculations. The simplicity in forward and Jacobian computation codes is very useful for operational applications and for the consistency between the forward and adjoint calculations in satellite data assimilation.

  17. Advanced stress analysis methods applicable to turbine engine structures

    NASA Technical Reports Server (NTRS)

    Pian, Theodore H. H.

    1991-01-01

    The following tasks on the study of advanced stress analysis methods applicable to turbine engine structures are described: (1) constructions of special elements which contain traction-free circular boundaries; (2) formulation of new version of mixed variational principles and new version of hybrid stress elements; (3) establishment of methods for suppression of kinematic deformation modes; (4) construction of semiLoof plate and shell elements by assumed stress hybrid method; and (5) elastic-plastic analysis by viscoplasticity theory using the mechanical subelement model.

  18. Imaging the Sub-Tropical Front off the southeast coast of New Zealand's South Island using high-frequency seismic methods

    NASA Astrophysics Data System (ADS)

    Gorman, A. R.; Bowman, M. H.

    2010-12-01

    The Sub-Tropical Front off the SE coast of New Zealand is an enigmatic ocean boundary that separates sub-tropical waters that are generally warm, low in nutrients, and sustain high levels of phytoplankton growth (primary productivity) from sub-antarctic waters that are generally cold, high in nutrients, and low in productivity. This region regularly exhibits evidence of nutrient transport across the Sub-Tropical Front that suggests significant ocean mixing across the front resulting in the transfer of iron from sub-tropical to sub-antarctic waters. Conventional ship-based oceanographic methods are incapable of observing these processes due to their sporadic and spatially-constrained nature. Seismic oceanographic methods have been shown to provide a means to image water body interactions such as these. However, a significant deficiency in current seismic oceanography imaging (i.e., using standard airgun profiles) is a failure to image the upper ~150 m of the ocean. This is due to: (1) the masking of shallow reflections by high-amplitude direct arrivals, and (2) the relatively large setback of the first receivers (typically ~200 m), which restricts shallow reflections to large angles of incidence. High-resolution profiling methods, usually used for shallow sub-bottom profiling, address both of these points, given (1) the low energy level of the sources and (2) the close proximity of the hydrophones. In addition to being a new technique for imaging the water column, such methods (with frequency characteristics that cover a large range of possible targets) have the potential to fill in a critical gap in existing seismic oceanography techniques. These methods also are much less expensive (at least over some depth ranges) than conventional methods that use large dedicated seismic vessels. We present first results from a 55-km-long coast-perpendicular transect across the Sub-Tropical Front off the SE coast of New Zealand. The transect is divided into seven segments by

  19. Advanced three-dimensional dynamic analysis by boundary element methods

    NASA Technical Reports Server (NTRS)

    Banerjee, P. K.; Ahma, S.

    1985-01-01

    Advanced formulations of boundary element method for periodic, transient transform domain and transient time domain solution of three-dimensional solids have been implemented using a family of isoparametric boundary elements. The necessary numerical integration techniques as well as the various solution algorithms are described. The developed analysis has been incorporated in a fully general purpose computer program BEST3D which can handle up to 10 subregions. A number of numerical examples are presented to demonstrate the accuracy of the dynamic analyses.

  20. Advanced boundary element methods in aeroacoustics and elastodynamics

    NASA Astrophysics Data System (ADS)

    Lee, Li

    In the first part of this dissertation, advanced boundary element methods (BEM) are developed for acoustic radiation in the presence of subsonic flows. A direct boundary integral formulation is first introduced for acoustic radiation in a uniform flow. This new formulation uses the Green's function derived from the adjoint operator of the governing differential equation. Therefore, it requires no coordinate transformation. This direct BEM formulation is then extended to acoustic radiation in a nonuniform-flow field. All the terms due to the nonuniform-flow effect are taken to the right-hand side and treated as source terms. The source terms result in a domain integral in the standard boundary integral formulation. The dual reciprocity method is then used to convert the domain integral into a number of boundary integrals. The second part of this dissertation is devoted to the development of advanced BEM algorithms to overcome the multi-frequency and nonuniqueness difficulties in steady-state elastodynamics. For the multi-frequency difficulty, two different interpolation schemes, borrowed from recent developments in acoustics, are first extended to elastodynamics to accelerate the process of matrix re-formation. Then, a hybrid scheme that retains only the merits of the two different interpolation schemes is suggested. To overcome the nonuniqueness difficulty, an enhanced CHIEF (Combined Helmholtz Integral Equation Formulation) method using a linear combination of the displacement and the traction boundary integral equations on the surface of a small interior volume is proposed. Numerical examples are given to demonstrate all the advanced BEM formulations.

  1. Advances in Statistical Methods for Substance Abuse Prevention Research

    PubMed Central

    MacKinnon, David P.; Lockwood, Chondra M.

    2010-01-01

    The paper describes advances in statistical methods for prevention research with a particular focus on substance abuse prevention. Standard analysis methods are extended to the typical research designs and characteristics of the data collected in prevention research. Prevention research often includes longitudinal measurement, clustering of data in units such as schools or clinics, missing data, and categorical as well as continuous outcome variables. Statistical methods to handle these features of prevention data are outlined. Developments in mediation, moderation, and implementation analysis allow for the extraction of more detailed information from a prevention study. Advancements in the interpretation of prevention research results include more widespread calculation of effect size and statistical power, the use of confidence intervals as well as hypothesis testing, detailed causal analysis of research findings, and meta-analysis. The increased availability of statistical software has contributed greatly to the use of new methods in prevention research. It is likely that the Internet will continue to stimulate the development and application of new methods. PMID:12940467

  2. ARIEL front end

    NASA Astrophysics Data System (ADS)

    Marchetto, M.; Baartman, R. A.; Laxdal, R. E.

    2014-01-01

    The ARIEL project at TRIUMF will greatly expand the variety and availability of radioactive ion beams (RIBs) (Laxdal, Nucl Inst Methods Phys Res B 204:400-409, 2003). The ARIEL front end connects the two ARIEL target stations to the existing ISAC facility to expand delivery to two and eventually three simultaneous RIB beams with up to two simultaneous accelerated beams (Laxdal et al. 2008). The low-energy beam transport lines and mass separators are designed for maximum flexibility to allow a variety of operational modes in order to optimize the radioactive ion beam delivery. A new accelerator path is conceived for high mass delivery from an EBIS charge state breeder. The front-end design utilizes the experience gained in 15 years of ISAC beam delivery.

  3. Weather fronts and acute myocardial infarction

    NASA Astrophysics Data System (ADS)

    Kveton, Vit

    1991-03-01

    Some methodological aspects are discussed of the investigation of acute infarct myocarditis (AIM) in relation to weather fronts. Results of a new method of analysis are given. Data were analysed from about the hour of the onset of symptoms, and led to the diagnosis of AIM either immediately or within a few hours or days (3019 cases observed over 4.5 years during 1982 1986 in Plzen, Czechoslovakia). Weather classification was based on three factors (the type of the foregoing front, the type of the subsequent front, the time section of the time interval demarcated by the passage of the surfaces of the fronts). AIM occurrence increased in particular types of weather fronts: (i) by 30% during 7 12 h after a warm front, if the time span between fronts exceeded 24 h; (ii) by 10% in time at least 36 h distant from the foregoing cold or occlusion front and from the succeeding warm or occlusion front; (iii) by 20% during 0 2 h before the passage of the front, provided the foregoing front was not warm and the interval between fronts exceeded 5 h. AIM occurrence decreased by 15% 20% for time span between fronts > 24 h at times 6 11, 6 23 and 6 35 h before a coming warm or occlusion front (for interfrontal intervals 25 48, 49 72 and possibly > 72 h), and also at 12 23 and possibly 12 35 h before a cold front (for intervals 49 72 and possibly > 72 h), if the foregoing front was cold or an occlusion front.

  4. Advanced reactor physics methods for heterogeneous reactor cores

    NASA Astrophysics Data System (ADS)

    Thompson, Steven A.

    To maintain the economic viability of nuclear power the industry has begun to emphasize maximizing the efficiency and output of existing nuclear power plants by using longer fuel cycles, stretch power uprates, shorter outage lengths, mixed-oxide (MOX) fuel and more aggressive operating strategies. In order to accommodate these changes, while still satisfying the peaking factor and power envelope requirements necessary to maintain safe operation, more complexity in commercial core designs have been implemented, such as an increase in the number of sub-batches and an increase in the use of both discrete and integral burnable poisons. A consequence of the increased complexity of core designs, as well as the use of MOX fuel, is an increase in the neutronic heterogeneity of the core. Such heterogeneous cores introduce challenges for the current methods that are used for reactor analysis. New methods must be developed to address these deficiencies while still maintaining the computational efficiency of existing reactor analysis methods. In this thesis, advanced core design methodologies are developed to be able to adequately analyze the highly heterogeneous core designs which are currently in use in commercial power reactors. These methodological improvements are being pursued with the goal of not sacrificing the computational efficiency which core designers require. More specifically, the PSU nodal code NEM is being updated to include an SP3 solution option, an advanced transverse leakage option, and a semi-analytical NEM solution option.

  5. Advanced Methods in Black-Hole Perturbation Theory

    NASA Astrophysics Data System (ADS)

    Pani, Paolo

    2013-09-01

    Black-hole perturbation theory is a useful tool to investigate issues in astrophysics, high-energy physics, and fundamental problems in gravity. It is often complementary to fully-fledged nonlinear evolutions and instrumental to interpret some results of numerical simulations. Several modern applications require advanced tools to investigate the linear dynamics of generic small perturbations around stationary black holes. Here, we present an overview of these applications and introduce extensions of the standard semianalytical methods to construct and solve the linearized field equations in curved space-time. Current state-of-the-art techniques are pedagogically explained and exciting open problems are presented.

  6. Simple front tracking

    SciTech Connect

    Glimm, J.; Grove, J.W.; Li, X.; Zhao, N.

    1999-04-01

    A new and simplified front tracking algorithm has been developed as an aspect of the extension of this algorithm to three dimensions. Here the authors emphasize two main results: (1) a simplified description of the microtopology of the interface, based on interface crossings with cell block edges, and (2) an improved algorithm for the interaction of a tracked contact discontinuity with an untracked shock wave. For the latter question, they focus on the post interaction jump at the contact, which is a purely 1D issue. Comparisons to other methods, including the level set method, are included.

  7. Methods and Systems for Advanced Spaceport Information Management

    NASA Technical Reports Server (NTRS)

    Fussell, Ronald M. (Inventor); Ely, Donald W. (Inventor); Meier, Gary M. (Inventor); Halpin, Paul C. (Inventor); Meade, Phillip T. (Inventor); Jacobson, Craig A. (Inventor); Blackwell-Thompson, Charlie (Inventor)

    2007-01-01

    Advanced spaceport information management methods and systems are disclosed. In one embodiment, a method includes coupling a test system to the payload and transmitting one or more test signals that emulate an anticipated condition from the test system to the payload. One or more responsive signals are received from the payload into the test system and are analyzed to determine whether one or more of the responsive signals comprises an anomalous signal. At least one of the steps of transmitting, receiving, analyzing and determining includes transmitting at least one of the test signals and the responsive signals via a communications link from a payload processing facility to a remotely located facility. In one particular embodiment, the communications link is an Internet link from a payload processing facility to a remotely located facility (e.g. a launch facility, university, etc.).

  8. Methods and systems for advanced spaceport information management

    NASA Technical Reports Server (NTRS)

    Fussell, Ronald M. (Inventor); Ely, Donald W. (Inventor); Meier, Gary M. (Inventor); Halpin, Paul C. (Inventor); Meade, Phillip T. (Inventor); Jacobson, Craig A. (Inventor); Blackwell-Thompson, Charlie (Inventor)

    2007-01-01

    Advanced spaceport information management methods and systems are disclosed. In one embodiment, a method includes coupling a test system to the payload and transmitting one or more test signals that emulate an anticipated condition from the test system to the payload. One or more responsive signals are received from the payload into the test system and are analyzed to determine whether one or more of the responsive signals comprises an anomalous signal. At least one of the steps of transmitting, receiving, analyzing and determining includes transmitting at least one of the test signals and the responsive signals via a communications link from a payload processing facility to a remotely located facility. In one particular embodiment, the communications link is an Internet link from a payload processing facility to a remotely located facility (e.g. a launch facility, university, etc.).

  9. Advances in direct and diffraction methods for surface structural determination

    NASA Astrophysics Data System (ADS)

    Tong, S. Y.

    1999-08-01

    I describe recent advances in low-energy electron diffraction holography and photoelectron diffraction holography. These are direct methods for determining the surface structure. I show that for LEED and PD spectra taken in an energy and angular mesh, the relative phase between the reference wave and the scattered wave has a known geometric form if the spectra are always taken from within a small angular cone in the near backscattering direction. By using data in the backscattering small cone at each direction of interest, a simple algorithm is developed to invert the spectra and extract object atomic positions with no input of calculated dynamic factors. I also describe the use of a convergent iterative method of PD and LEED. The computation time of this method scales as N2, where N is the dimension of the propagator matrix, rather than N3 as in conventional Gaussian substitutional methods. Both the Rehr-Albers separable-propagator cluster approach and the slab-type non-separable approach can be cast in the new iterative form. With substantial savings in computational time and no loss in numerical accuracy, this method is very useful in applications of multiple scattering theory, particularly for systems involving either very large unit cells (>300 atoms) or where no long-range order is present.

  10. Advances in the Surface Renewal Flux Measurement Method

    NASA Astrophysics Data System (ADS)

    Shapland, T. M.; McElrone, A.; Paw U, K. T.; Snyder, R. L.

    2011-12-01

    The measurement of ecosystem-scale energy and mass fluxes between the planetary surface and the atmosphere is crucial for understanding geophysical processes. Surface renewal is a flux measurement technique based on analyzing the turbulent coherent structures that interact with the surface. It is a less expensive technique because it does not require fast-response velocity measurements, but only a fast-response scalar measurement. It is therefore also a useful tool for the study of the global cycling of trace gases. Currently, surface renewal requires calibration against another flux measurement technique, such as eddy covariance, to account for the linear bias of its measurements. We present two advances in the surface renewal theory and methodology that bring the technique closer to becoming a fully independent flux measurement method. The first advance develops the theory of turbulent coherent structure transport associated with the different scales of coherent structures. A novel method was developed for identifying the scalar change rate within structures at different scales. Our results suggest that for canopies less than one meter in height, the second smallest coherent structure scale dominates the energy and mass flux process. Using the method for resolving the scalar exchange rate of the second smallest coherent structure scale, calibration is unnecessary for surface renewal measurements over short canopies. This study forms the foundation for analysis over more complex surfaces. The second advance is a sensor frequency response correction for measuring the sensible heat flux via surface renewal. Inexpensive fine-wire thermocouples are frequently used to record high frequency temperature data in the surface renewal technique. The sensible heat flux is used in conjunction with net radiation and ground heat flux measurements to determine the latent heat flux as the energy balance residual. The robust thermocouples commonly used in field experiments

  11. Advanced superposition methods for high speed turbopump vibration analysis

    NASA Technical Reports Server (NTRS)

    Nielson, C. E.; Campany, A. D.

    1981-01-01

    The small, high pressure Mark 48 liquid hydrogen turbopump was analyzed and dynamically tested to determine the cause of high speed vibration at an operating speed of 92,400 rpm. This approaches the design point operating speed of 95,000 rpm. The initial dynamic analysis in the design stage and subsequent further analysis of the rotor only dynamics failed to predict the vibration characteristics found during testing. An advanced procedure for dynamics analysis was used in this investigation. The procedure involves developing accurate dynamic models of the rotor assembly and casing assembly by finite element analysis. The dynamically instrumented assemblies are independently rap tested to verify the analytical models. The verified models are then combined by modal superposition techniques to develop a completed turbopump model where dynamic characteristics are determined. The results of the dynamic testing and analysis obtained are presented and methods of moving the high speed vibration characteristics to speeds above the operating range are recommended. Recommendations for use of these advanced dynamic analysis procedures during initial design phases are given.

  12. Recent advances in computational structural reliability analysis methods

    NASA Technical Reports Server (NTRS)

    Thacker, Ben H.; Wu, Y.-T.; Millwater, Harry R.; Torng, Tony Y.; Riha, David S.

    1993-01-01

    The goal of structural reliability analysis is to determine the probability that the structure will adequately perform its intended function when operating under the given environmental conditions. Thus, the notion of reliability admits the possibility of failure. Given the fact that many different modes of failure are usually possible, achievement of this goal is a formidable task, especially for large, complex structural systems. The traditional (deterministic) design methodology attempts to assure reliability by the application of safety factors and conservative assumptions. However, the safety factor approach lacks a quantitative basis in that the level of reliability is never known and usually results in overly conservative designs because of compounding conservatisms. Furthermore, problem parameters that control the reliability are not identified, nor their importance evaluated. A summary of recent advances in computational structural reliability assessment is presented. A significant level of activity in the research and development community was seen recently, much of which was directed towards the prediction of failure probabilities for single mode failures. The focus is to present some early results and demonstrations of advanced reliability methods applied to structural system problems. This includes structures that can fail as a result of multiple component failures (e.g., a redundant truss), or structural components that may fail due to multiple interacting failure modes (e.g., excessive deflection, resonate vibration, or creep rupture). From these results, some observations and recommendations are made with regard to future research needs.

  13. Integration of isothermal amplification methods in microfluidic devices: Recent advances.

    PubMed

    Giuffrida, Maria Chiara; Spoto, Giuseppe

    2017-04-15

    The integration of nucleic acids detection assays in microfluidic devices represents a highly promising approach for the development of convenient, cheap and efficient diagnostic tools for clinical, food safety and environmental monitoring applications. Such tools are expected to operate at the point-of-care and in resource-limited settings. The amplification of the target nucleic acid sequence represents a key step for the development of sensitive detection protocols. The integration in microfluidic devices of the most popular technology for nucleic acids amplifications, polymerase chain reaction (PCR), is significantly limited by the thermal cycling needed to obtain the target sequence amplification. This review provides an overview of recent advances in integration of isothermal amplification methods in microfluidic devices. Isothermal methods, that operate at constant temperature, have emerged as promising alternative to PCR and greatly simplify the implementation of amplification methods in point-of-care diagnostic devices and devices to be used in resource-limited settings. Possibilities offered by isothermal methods for digital droplet amplification are discussed.

  14. Advances in nondestructive evaluation methods for inspection of refractory concretes

    SciTech Connect

    Ellingson, W. A.

    1980-01-01

    Refractory concrete linings are essential to protect steel pressure boundaries from high-temperature agressive erosive/corrosive environments. Castable refractory concretes have been gaining more acceptance as information about their performance increases. Economic factors, however, have begun to impose high demands on the reliability of refractory materials. Advanced nondestructive evaluation methods are being developed to assist the refractory user. Radiographic techniques, thermography, acoustic-emission detection, and interferometry have been shown to yield information on the structural status of refractory concrete. Methods using /sup 60/Co radiation sources are capable of yielding measurements of refractory wear rate as well as images of cracks and/or voids in pre- and post-fired refractory linings up to 60 cm thick. Thermographic (infrared) images serve as a qualitative indicator of refractory spalling, but quantitative measurements are difficult to obtain from surface-temperature mapping. Acoustic emission has been shown to be a qualitative indicator of thermomechanical degradation of thick panels of 50 and 95% Al/sub 2/O/sub 3/ during initial heating and cooling at rates of 100 to 220/sup 0/C/h. Laser interferometry methods have been shown to be capable of complete mappings of refractory lining thicknesses. This paper will present results obtained from laboratory and field applications of these methods in petrochemical, steel, and coal-conversion plants.

  15. Exploration of Advanced Probabilistic and Stochastic Design Methods

    NASA Technical Reports Server (NTRS)

    Mavris, Dimitri N.

    2003-01-01

    The primary objective of the three year research effort was to explore advanced, non-deterministic aerospace system design methods that may have relevance to designers and analysts. The research pursued emerging areas in design methodology and leverage current fundamental research in the area of design decision-making, probabilistic modeling, and optimization. The specific focus of the three year investigation was oriented toward methods to identify and analyze emerging aircraft technologies in a consistent and complete manner, and to explore means to make optimal decisions based on this knowledge in a probabilistic environment. The research efforts were classified into two main areas. First, Task A of the grant has had the objective of conducting research into the relative merits of possible approaches that account for both multiple criteria and uncertainty in design decision-making. In particular, in the final year of research, the focus was on the comparison and contrasting between three methods researched. Specifically, these three are the Joint Probabilistic Decision-Making (JPDM) technique, Physical Programming, and Dempster-Shafer (D-S) theory. The next element of the research, as contained in Task B, was focused upon exploration of the Technology Identification, Evaluation, and Selection (TIES) methodology developed at ASDL, especially with regards to identification of research needs in the baseline method through implementation exercises. The end result of Task B was the documentation of the evolution of the method with time and a technology transfer to the sponsor regarding the method, such that an initial capability for execution could be obtained by the sponsor. Specifically, the results of year 3 efforts were the creation of a detailed tutorial for implementing the TIES method. Within the tutorial package, templates and detailed examples were created for learning and understanding the details of each step. For both research tasks, sample files and

  16. Advanced Motion Compensation Methods for Intravital Optical Microscopy

    PubMed Central

    Vinegoni, Claudio; Lee, Sungon; Feruglio, Paolo Fumene; Weissleder, Ralph

    2013-01-01

    Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the micro-dynamics of biological processes in live animals. Technical advancements in imaging techniques and hardware components, combined with the development of novel targeted probes and new mice models, have enabled us to address long-standing questions in several biology areas such as oncology, cell biology, immunology and neuroscience. As the instrument resolution has increased, physiological motion activities have become a major obstacle that prevents imaging live animals at resolutions analogue to the ones obtained in vitro. Motion compensation techniques aim at reducing this gap and can effectively increase the in vivo resolution. This paper provides a technical review of some of the latest developments in motion compensation methods, providing organ specific solutions. PMID:24273405

  17. Computational methods of the Advanced Fluid Dynamics Model

    SciTech Connect

    Bohl, W.R.; Wilhelm, D.; Parker, F.R.; Berthier, J.; Maudlin, P.J.; Schmuck, P.; Goutagny, L.; Ichikawa, S.; Ninokata, H.; Luck, L.B.

    1987-01-01

    To more accurately treat severe accidents in fast reactors, a program has been set up to investigate new computational models and approaches. The product of this effort is a computer code, the Advanced Fluid Dynamics Model (AFDM). This paper describes some of the basic features of the numerical algorithm used in AFDM. Aspects receiving particular emphasis are the fractional-step method of time integration, the semi-implicit pressure iteration, the virtual mass inertial terms, the use of three velocity fields, higher order differencing, convection of interfacial area with source and sink terms, multicomponent diffusion processes in heat and mass transfer, the SESAME equation of state, and vectorized programming. A calculated comparison with an isothermal tetralin/ammonia experiment is performed. We conclude that significant improvements are possible in reliably calculating the progression of severe accidents with further development.

  18. Advancing MODFLOW Applying the Derived Vector Space Method

    NASA Astrophysics Data System (ADS)

    Herrera, G. S.; Herrera, I.; Lemus-García, M.; Hernandez-Garcia, G. D.

    2015-12-01

    The most effective domain decomposition methods (DDM) are non-overlapping DDMs. Recently a new approach, the DVS-framework, based on an innovative discretization method that uses a non-overlapping system of nodes (the derived-nodes), was introduced and developed by I. Herrera et al. [1, 2]. Using the DVS-approach a group of four algorithms, referred to as the 'DVS-algorithms', which fulfill the DDM-paradigm (i.e. the solution of global problems is obtained by resolution of local problems exclusively) has been derived. Such procedures are applicable to any boundary-value problem, or system of such equations, for which a standard discretization method is available and then software with a high degree of parallelization can be constructed. In a parallel talk, in this AGU Fall Meeting, Ismael Herrera will introduce the general DVS methodology. The application of the DVS-algorithms has been demonstrated in the solution of several boundary values problems of interest in Geophysics. Numerical examples for a single-equation, for the cases of symmetric, non-symmetric and indefinite problems were demonstrated before [1,2]. For these problems DVS-algorithms exhibited significantly improved numerical performance with respect to standard versions of DDM algorithms. In view of these results our research group is in the process of applying the DVS method to a widely used simulator for the first time, here we present the advances of the application of this method for the parallelization of MODFLOW. Efficiency results for a group of tests will be presented. References [1] I. Herrera, L.M. de la Cruz and A. Rosas-Medina. Non overlapping discretization methods for partial differential equations, Numer Meth Part D E, (2013). [2] Herrera, I., & Contreras Iván "An Innovative Tool for Effectively Applying Highly Parallelized Software To Problems of Elasticity". Geofísica Internacional, 2015 (In press)

  19. Advances in Time Estimation Methods for Molecular Data.

    PubMed

    Kumar, Sudhir; Hedges, S Blair

    2016-04-01

    Molecular dating has become central to placing a temporal dimension on the tree of life. Methods for estimating divergence times have been developed for over 50 years, beginning with the proposal of molecular clock in 1962. We categorize the chronological development of these methods into four generations based on the timing of their origin. In the first generation approaches (1960s-1980s), a strict molecular clock was assumed to date divergences. In the second generation approaches (1990s), the equality of evolutionary rates between species was first tested and then a strict molecular clock applied to estimate divergence times. The third generation approaches (since ∼2000) account for differences in evolutionary rates across the tree by using a statistical model, obviating the need to assume a clock or to test the equality of evolutionary rates among species. Bayesian methods in the third generation require a specific or uniform prior on the speciation-process and enable the inclusion of uncertainty in clock calibrations. The fourth generation approaches (since 2012) allow rates to vary from branch to branch, but do not need prior selection of a statistical model to describe the rate variation or the specification of speciation model. With high accuracy, comparable to Bayesian approaches, and speeds that are orders of magnitude faster, fourth generation methods are able to produce reliable timetrees of thousands of species using genome scale data. We found that early time estimates from second generation studies are similar to those of third and fourth generation studies, indicating that methodological advances have not fundamentally altered the timetree of life, but rather have facilitated time estimation by enabling the inclusion of more species. Nonetheless, we feel an urgent need for testing the accuracy and precision of third and fourth generation methods, including their robustness to misspecification of priors in the analysis of large phylogenies and data

  20. Method Evaluation And Field Sample Measurements For The Rate Of Movement Of The Oxidation Front In Saltstone

    SciTech Connect

    Almond, P. M.; Kaplan, D. I.; Langton, C. A.; Stefanko, D. B.; Spencer, W. A.; Hatfield, A.; Arai, Y.

    2012-08-23

    The objective of this work was to develop and evaluate a series of methods and validate their capability to measure differences in oxidized versus reduced saltstone. Validated methods were then applied to samples cured under field conditions to simulate Performance Assessment (PA) needs for the Saltstone Disposal Facility (SDF). Four analytical approaches were evaluated using laboratory-cured saltstone samples. These methods were X-ray absorption spectroscopy (XAS), diffuse reflectance spectroscopy (DRS), chemical redox indicators, and thin-section leaching methods. XAS and thin-section leaching methods were validated as viable methods for studying oxidation movement in saltstone. Each method used samples that were spiked with chromium (Cr) as a tracer for oxidation of the saltstone. The two methods were subsequently applied to field-cured samples containing chromium to characterize the oxidation state of chromium as a function of distance from the exposed air/cementitious material surface.

  1. [Contemporary methods of treatment in local advanced prostate cancer].

    PubMed

    Brzozowska, Anna; Mazurkiewicz, Maria; Starosławska, Elzbieta; Stasiewicz, Dominika; Mocarska, Agnieszka; Burdan, Franciszek

    2012-10-01

    The prostate cancer is one of the most often cancers amongst males. Its frequency is increasing with age. Thanks to widespread of screening denomination of specific prostate specific antigen (PSA), ultrasonography including the one in transrectal (TRUS), computed tomography, magnetic resonance and especially the awareness of society, the number of patients with low local advance of illness is increasing. The basic method of treatment in such cases is still the surgical removal of prostate with seminal bladder or radiotherapy. To this purpose tele-(IMRT, VMAT) or brachytherapy (J125, Ir192, Pa103) is used. In patients with higher risk of progression the radiotherapy may be associated with hormonotherapy (total androgen blockage-LH-RH analog and androgen). Despite numerous clinical researches conducted there is still no selection of optimal sequence of particular methods. Moreover, no explicit effectiveness was determined. The general rule of treatment in patients suffering from prostate cancer still remains individual selection of therapeutic treatment depending on the age of a patient, general condition and especially patient's general preferences. In case of elderly patients and patients with low risk of progression, recommendation of direct observation including systematical PSA denomination, clinical transrectal examination, TRUS, MR of smaller pelvis or scintigraphy of the whole skeleton may be considered.

  2. Smart x-ray beam position monitor system using artificial intelligence methods for the Advanced Photon Source insertion-device beamlines

    SciTech Connect

    Shu, D.; Ding, H.; Barraza, J.; Kuzay, T.M.; Haeffner, D.; Ramanathan, M.

    1997-09-01

    At the Advanced Photon Source (APS), each insertion device (ID) beamline front-end has two XBPMs to monitor the X-ray beam position for both that vertical and horizontal directions. Performance challenges for a conventional photoemission type X-ray beam position monitor (XBPM) during operations are contamination of the signal from the neighboring bending magnet sources and the sensitivity of the XBPM to the insertion device (ID) gap variations. Problems are exacerbated because users change the ID gap during their operations, and hence the percentage level of the contamination in the front end XBPM signals varies. A smart XBPM system with a high speed digital signal processor has been built at the Advanced Photon Source for the ID beamline front ends. The new version of the software, which uses an artificial intelligence method, provides a self learning and self-calibration capability to the smart XBPM system. The structure of and recent test results with the system are presented in this paper.

  3. Measuring Delta Progradation Using Delta Front Flow Patterns: A New Method of Remote Imagery Analysis on the Wax Lake Delta, Louisiana, U.S.A.

    NASA Astrophysics Data System (ADS)

    Estep, J. D.; Shaw, J.; Edmonds, D. A.

    2015-12-01

    Quantifying the progradation of the Wax Lake Delta (WLD), a sub-delta of the Mississippi River Delta, can lend valuable insight into coastal land-building patterns. Previous studies of WLD progradation have relied on subaerially-exposed land for indicating delta extent, but an inherent problem with this method lies in the high variability of exposed land due to vegetative, hydrologic, and atmospheric fluctuations. By mapping water surface films observed in remote imagery which form streaklines along flow paths in the delta, we show that the shallow delta front flow patterns are relatively unaffected by short term water level changes and can be used to evaluate WLD progradation over time. Remotely sensed imagery from multiple sources (infrared aerial photography, SPOT, UAVSAR) spanning from 1988 to 2015 was used to map streaklines from which we calculate a flow direction divergence field across the delta. Measuring the translation of this field through time, such as areas containing extreme divergence values along the delta front, quantifies the progradation over the time elapsed. Preliminary measurements of WLD progradation were subdivided into the eastern, southern, and western thirds of the delta. The eastern third prograded at 110 ±20m/yr from 1988 - 1997, 100 ±40m/yr from 1997 - 2002, and then remained relatively constant to 2015. The southern third prograded at 130 ±20m/yr from 1988 - 1997, 200 ±40m/yr from 1997 - 2002, and remained relatively constant to 2015. The western third prograded at 130 ±30m/yr from 1988 - 1997, 220 ±60 m from 1997 - 2002, and then remained relatively constant from 2002 - 2015. Also of note is the retrogradation on the average of 700 ±400m observed from January to August, 1992 which we interpret as being caused by the impact of Hurricane Andrew. The streakline methodology of evaluating WLD progradation could provide new methods for analysis of land change in other deltas around the world.

  4. Striking against bioterrorism with advanced proteomics and reference methods.

    PubMed

    Armengaud, Jean

    2017-01-01

    The intentional use by terrorists of biological toxins as weapons has been of great concern for many years. Among the numerous toxins produced by plants, animals, algae, fungi, and bacteria, ricin is one of the most scrutinized by the media because it has already been used in biocrimes and acts of bioterrorism. Improving the analytical toolbox of national authorities to monitor these potential bioweapons all at once is of the utmost interest. MS/MS allows their absolute quantitation and exhibits advantageous sensitivity, discriminative power, multiplexing possibilities, and speed. In this issue of Proteomics, Gilquin et al. (Proteomics 2017, 17, 1600357) present a robust multiplex assay to quantify a set of eight toxins in the presence of a complex food matrix. This MS/MS reference method is based on scheduled SRM and high-quality standards consisting of isotopically labeled versions of these toxins. Their results demonstrate robust reliability based on rather loose scheduling of SRM transitions and good sensitivity for the eight toxins, lower than their oral median lethal doses. In the face of an increased threat from terrorism, relevant reference assays based on advanced proteomics and high-quality companion toxin standards are reliable and firm answers.

  5. Underwater Photosynthesis of Submerged Plants – Recent Advances and Methods

    PubMed Central

    Pedersen, Ole; Colmer, Timothy D.; Sand-Jensen, Kaj

    2013-01-01

    We describe the general background and the recent advances in research on underwater photosynthesis of leaf segments, whole communities, and plant dominated aquatic ecosystems and present contemporary methods tailor made to quantify photosynthesis and carbon fixation under water. The majority of studies of aquatic photosynthesis have been carried out with detached leaves or thalli and this selectiveness influences the perception of the regulation of aquatic photosynthesis. We thus recommend assessing the influence of inorganic carbon and temperature on natural aquatic communities of variable density in addition to studying detached leaves in the scenarios of rising CO2 and temperature. Moreover, a growing number of researchers are interested in tolerance of terrestrial plants during flooding as torrential rains sometimes result in overland floods that inundate terrestrial plants. We propose to undertake studies to elucidate the importance of leaf acclimation of terrestrial plants to facilitate gas exchange and light utilization under water as these acclimations influence underwater photosynthesis as well as internal aeration of plant tissues during submergence. PMID:23734154

  6. Advances in the analysis of iminocyclitols: Methods, sources and bioavailability.

    PubMed

    Amézqueta, Susana; Torres, Josep Lluís

    2016-05-01

    Iminocyclitols are chemically and metabolically stable, naturally occurring sugar mimetics. Their biological activities make them interesting and extremely promising as both drug leads and functional food ingredients. The first iminocyclitols were discovered using preparative isolation and purification methods followed by chemical characterization using nuclear magnetic resonance spectroscopy. In addition to this classical approach, gas and liquid chromatography coupled to mass spectrometry are increasingly used; they are highly sensitive techniques capable of detecting minute amounts of analytes in a broad spectrum of sources after only minimal sample preparation. These techniques have been applied to identify new iminocyclitols in plants, microorganisms and synthetic mixtures. The separation of iminocyclitol mixtures by chromatography is particularly difficult however, as the most commonly used matrices have very low selectivity for these highly hydrophilic structurally similar molecules. This review critically summarizes recent advances in the analysis of iminocyclitols from plant sources and findings regarding their quantification in dietary supplements and foodstuffs, as well as in biological fluids and organs, from bioavailability studies.

  7. Regenerative medicine: advances in new methods and technologies.

    PubMed

    Park, Dong-Hyuk; Eve, David J

    2009-11-01

    The articles published in the journal Cell Transplantation - The Regenerative Medicine Journal over the last two years reveal the recent and future cutting-edge research in the fields of regenerative and transplantation medicine. 437 articles were published from 2007 to 2008, a 17% increase compared to the 373 articles in 2006-2007. Neuroscience was still the most common section in both the number of articles and the percentage of all manuscripts published. The increasing interest and rapid advance in bioengineering technology is highlighted by tissue engineering and bioartificial organs being ranked second again. For a similar reason, the methods and new technologies section increased significantly compared to the last period. Articles focusing on the transplantation of stem cell lineages encompassed almost 20% of all articles published. By contrast, the non-stem cell transplantation group which is made up primarily of islet cells, followed by biomaterials and fetal neural tissue, etc. comprised less than 15%. Transplantation of cells pre-treated with medicine or gene transfection to prolong graft survival or promote differentiation into the needed phenotype, was prevalent in the transplantation articles regardless of the kind of cells used. Meanwhile, the majority of non-transplantation-based articles were related to new devices for various purposes, characterization of unknown cells, medicines, cell preparation and/or optimization for transplantation (e.g. isolation and culture), and disease pathology.

  8. Bioinformatics Methods and Tools to Advance Clinical Care

    PubMed Central

    Lecroq, T.

    2015-01-01

    Summary Objectives To summarize excellent current research in the field of Bioinformatics and Translational Informatics with application in the health domain and clinical care. Method We provide a synopsis of the articles selected for the IMIA Yearbook 2015, from which we attempt to derive a synthetic overview of current and future activities in the field. As last year, a first step of selection was performed by querying MEDLINE with a list of MeSH descriptors completed by a list of terms adapted to the section. Each section editor has evaluated separately the set of 1,594 articles and the evaluation results were merged for retaining 15 articles for peer-review. Results The selection and evaluation process of this Yearbook’s section on Bioinformatics and Translational Informatics yielded four excellent articles regarding data management and genome medicine that are mainly tool-based papers. In the first article, the authors present PPISURV a tool for uncovering the role of specific genes in cancer survival outcome. The second article describes the classifier PredictSNP which combines six performing tools for predicting disease-related mutations. In the third article, by presenting a high-coverage map of the human proteome using high resolution mass spectrometry, the authors highlight the need for using mass spectrometry to complement genome annotation. The fourth article is also related to patient survival and decision support. The authors present datamining methods of large-scale datasets of past transplants. The objective is to identify chances of survival. Conclusions The current research activities still attest the continuous convergence of Bioinformatics and Medical Informatics, with a focus this year on dedicated tools and methods to advance clinical care. Indeed, there is a need for powerful tools for managing and interpreting complex, large-scale genomic and biological datasets, but also a need for user-friendly tools developed for the clinicians in their

  9. Advances in Experimental Neuropathology: New Methods and Insights.

    PubMed

    Roth, Kevin A

    2016-03-01

    This Editorial introduces this month's special Neuropathology Theme Issue, a series of Reviews on advances in our understanding of rare human hereditary neuropathies, peripheral nervous system tumors, and common degenerative diseases.

  10. ADVANCED SEISMIC BASE ISOLATION METHODS FOR MODULAR REACTORS

    SciTech Connect

    E. Blanford; E. Keldrauk; M. Laufer; M. Mieler; J. Wei; B. Stojadinovic; P.F. Peterson

    2010-09-20

    Advanced technologies for structural design and construction have the potential for major impact not only on nuclear power plant construction time and cost, but also on the design process and on the safety, security and reliability of next generation of nuclear power plants. In future Generation IV (Gen IV) reactors, structural and seismic design should be much more closely integrated with the design of nuclear and industrial safety systems, physical security systems, and international safeguards systems. Overall reliability will be increased, through the use of replaceable and modular equipment, and through design to facilitate on-line monitoring, in-service inspection, maintenance, replacement, and decommissioning. Economics will also receive high design priority, through integrated engineering efforts to optimize building arrangements to minimize building heights and footprints. Finally, the licensing approach will be transformed by becoming increasingly performance based and technology neutral, using best-estimate simulation methods with uncertainty and margin quantification. In this context, two structural engineering technologies, seismic base isolation and modular steel-plate/concrete composite structural walls, are investigated. These technologies have major potential to (1) enable standardized reactor designs to be deployed across a wider range of sites, (2) reduce the impact of uncertainties related to site-specific seismic conditions, and (3) alleviate reactor equipment qualification requirements. For Gen IV reactors the potential for deliberate crashes of large aircraft must also be considered in design. This report concludes that base-isolated structures should be decoupled from the reactor external event exclusion system. As an example, a scoping analysis is performed for a rectangular, decoupled external event shell designed as a grillage. This report also reviews modular construction technology, particularly steel-plate/concrete construction using

  11. Direct measurement of the wetting front capillary pressure in a clay brick ceramic

    NASA Astrophysics Data System (ADS)

    Ioannou, Ioannis; Hall, Christopher; Wilson, Moira A.; Hoff, William D.; Carter, Margaret A.

    2003-12-01

    The absorption of a liquid into a rectangular bar of an initially dry porous material that is sealed on all surfaces except the inflow face is analysed in terms of Sharp Front theory. Sharp Front models are developed for both complete and incomplete displacement of air ahead of the advancing wetting front. Experiments are described from which a characteristic capillary potential of the material is obtained by measuring the equilibrium pressure of the air displaced and compressed ahead of the advancing wetting front. Results for the absorption of water and n-heptane by a fired clay brick ceramic suggest that this wetting front capillary pressure (or capillary potential) scales approximately with the surface tension and also that the permeability scales inversely with the liquid viscosity. The pressure of the air trapped in the wetted region is found to be the same as the pressure of the displaced air. For this material the wetting front capillary pressure for water at 20°C is 0.113 MPa, equivalent to a hydraulic tension head of 11.5 m and to a Young-Laplace pore diameter of 2.6 µm. The capillary pressure so measured is apparently a fundamental percolation property of the material that can be interpreted as the air pressure at which liquid phase continuity and unsaturated conductivity both vanish. The method described can be applied generally to porous materials.

  12. Processing of alnico permanent magnets by advanced directional solidification methods

    SciTech Connect

    Zou, Min; Johnson, Francis; Zhang, Wanming; Zhao, Qi; Rutkowski, Stephen F.; Zhou, Lin; Kramer, Matthew J.

    2016-07-05

    Advanced directional solidification methods have been used to produce large (>15 cm length) castings of Alnico permanent magnets with highly oriented columnar microstructures. In combination with subsequent thermomagnetic and draw thermal treatment, this method was used to enable the high coercivity, high-Titanium Alnico composition of 39% Co, 29.5% Fe, 14% Ni, 7.5% Ti, 7% Al, 3% Cu (wt%) to have an intrinsic coercivity (Hci) of 2.0 kOe, a remanence (Br) of 10.2 kG, and an energy product (BH)max of 10.9 MGOe. These properties compare favorably to typical properties for the commercial Alnico 9. Directional solidification of higher Ti compositions yielded anisotropic columnar grained microstructures if high heat extraction rates through the mold surface of at least 200 kW/m2 were attained. This was achieved through the use of a thin walled (5 mm thick) high thermal conductivity SiC shell mold extracted from a molten Sn bath at a withdrawal rate of at least 200 mm/h. However, higher Ti compositions did not result in further increases in magnet performance. Images of the microstructures collected by scanning electron microscopy (SEM) reveal a majority α phase with inclusions of secondary αγ phase. Transmission electron microscopy (TEM) reveals that the α phase has a spinodally decomposed microstructure of FeCo-rich needles in a NiAl-rich matrix. In the 7.5% Ti composition the diameter distribution of the FeCo needles was bimodal with the majority having diameters of approximately 50 nm with a small fraction having diameters of approximately 10 nm. The needles formed a mosaic pattern and were elongated along one <001> crystal direction (parallel to the field used during magnetic annealing). Cu precipitates were observed between the needles. Regions of abnormal spinodal morphology appeared to correlate with secondary phase precipitates. The presence of these abnormalities did not prevent the material from displaying

  13. Processing of alnico permanent magnets by advanced directional solidification methods

    DOE PAGES

    Zou, Min; Johnson, Francis; Zhang, Wanming; ...

    2016-07-05

    Advanced directional solidification methods have been used to produce large (>15 cm length) castings of Alnico permanent magnets with highly oriented columnar microstructures. In combination with subsequent thermomagnetic and draw thermal treatment, this method was used to enable the high coercivity, high-Titanium Alnico composition of 39% Co, 29.5% Fe, 14% Ni, 7.5% Ti, 7% Al, 3% Cu (wt%) to have an intrinsic coercivity (Hci) of 2.0 kOe, a remanence (Br) of 10.2 kG, and an energy product (BH)max of 10.9 MGOe. These properties compare favorably to typical properties for the commercial Alnico 9. Directional solidification of higher Ti compositions yieldedmore » anisotropic columnar grained microstructures if high heat extraction rates through the mold surface of at least 200 kW/m2 were attained. This was achieved through the use of a thin walled (5 mm thick) high thermal conductivity SiC shell mold extracted from a molten Sn bath at a withdrawal rate of at least 200 mm/h. However, higher Ti compositions did not result in further increases in magnet performance. Images of the microstructures collected by scanning electron microscopy (SEM) reveal a majority α phase with inclusions of secondary αγ phase. Transmission electron microscopy (TEM) reveals that the α phase has a spinodally decomposed microstructure of FeCo-rich needles in a NiAl-rich matrix. In the 7.5% Ti composition the diameter distribution of the FeCo needles was bimodal with the majority having diameters of approximately 50 nm with a small fraction having diameters of approximately 10 nm. The needles formed a mosaic pattern and were elongated along one <001> crystal direction (parallel to the field used during magnetic annealing). Cu precipitates were observed between the needles. Regions of abnormal spinodal morphology appeared to correlate with secondary phase precipitates. The presence of these abnormalities did not prevent the material from displaying superior magnetic properties in the 7.5% Ti

  14. Processing of alnico permanent magnets by advanced directional solidification methods

    NASA Astrophysics Data System (ADS)

    Zou, Min; Johnson, Francis; Zhang, Wanming; Zhao, Qi; Rutkowski, Stephen F.; Zhou, Lin; Kramer, Matthew J.

    2016-12-01

    Advanced directional solidification methods have been used to produce large (>15 cm length) castings of Alnico permanent magnets with highly oriented columnar microstructures. In combination with subsequent thermomagnetic and draw thermal treatment, this method was used to enable the high coercivity, high-Titanium Alnico composition of 39% Co, 29.5% Fe, 14% Ni, 7.5% Ti, 7% Al, 3% Cu (wt%) to have an intrinsic coercivity (Hci) of 2.0 kOe, a remanence (Br) of 10.2 kG, and an energy product (BH)max of 10.9 MGOe. These properties compare favorably to typical properties for the commercial Alnico 9. Directional solidification of higher Ti compositions yielded anisotropic columnar grained microstructures if high heat extraction rates through the mold surface of at least 200 kW/m2 were attained. This was achieved through the use of a thin walled (5 mm thick) high thermal conductivity SiC shell mold extracted from a molten Sn bath at a withdrawal rate of at least 200 mm/h. However, higher Ti compositions did not result in further increases in magnet performance. Images of the microstructures collected by scanning electron microscopy (SEM) reveal a majority α phase with inclusions of secondary αγ phase. Transmission electron microscopy (TEM) reveals that the α phase has a spinodally decomposed microstructure of FeCo-rich needles in a NiAl-rich matrix. In the 7.5% Ti composition the diameter distribution of the FeCo needles was bimodal with the majority having diameters of approximately 50 nm with a small fraction having diameters of approximately 10 nm. The needles formed a mosaic pattern and were elongated along one <001> crystal direction (parallel to the field used during magnetic annealing). Cu precipitates were observed between the needles. Regions of abnormal spinodal morphology appeared to correlate with secondary phase precipitates. The presence of these abnormalities did not prevent the material from displaying superior magnetic properties in the 7.5% Ti

  15. Current waveform reconstruction from an explosively emissive cathode at a subnanosecond voltage front

    SciTech Connect

    Sharypov, K. A. Ul'masculov, M. R.; Shpak, V. G.; Shunailov, S. A.; Yalandin, M. I.; Mesyats, G. A.; Rostov, V. V.

    2014-12-15

    We describe the methods of registration and reconstruction of an envelope of explosive electron emission current from the edge of a cylindrical cathode, which provides a picosecond time reference of the emitted electron beam with a subnanosecond voltage front applied to the accelerating gap. Variation of the front steepness allows one to determine the beam onset time in the experiments, where a collector-type current probe can be used. The advanced method of dynamic time domain reflectometry provides exact data on electron beam current rise and track changes in the cathode emission from pulse to pulse with a precision of less than 10 ps.

  16. Conceptual frameworks and methods for advancing invasion ecology.

    PubMed

    Heger, Tina; Pahl, Anna T; Botta-Dukát, Zoltan; Gherardi, Francesca; Hoppe, Christina; Hoste, Ivan; Jax, Kurt; Lindström, Leena; Boets, Pieter; Haider, Sylvia; Kollmann, Johannes; Wittmann, Meike J; Jeschke, Jonathan M

    2013-09-01

    Invasion ecology has much advanced since its early beginnings. Nevertheless, explanation, prediction, and management of biological invasions remain difficult. We argue that progress in invasion research can be accelerated by, first, pointing out difficulties this field is currently facing and, second, looking for measures to overcome them. We see basic and applied research in invasion ecology confronted with difficulties arising from (A) societal issues, e.g., disparate perceptions of invasive species; (B) the peculiarity of the invasion process, e.g., its complexity and context dependency; and (C) the scientific methodology, e.g., imprecise hypotheses. To overcome these difficulties, we propose three key measures: (1) a checklist for definitions to encourage explicit definitions; (2) implementation of a hierarchy of hypotheses (HoH), where general hypotheses branch into specific and precisely testable hypotheses; and (3) platforms for improved communication. These measures may significantly increase conceptual clarity and enhance communication, thus advancing invasion ecology.

  17. Production of hybrid granitic magma at the advancing front of basaltic underplating: Inferences from the Sesia Magmatic System (south-western Alps, Italy)

    NASA Astrophysics Data System (ADS)

    Sinigoi, Silvano; Quick, James E.; Demarchi, Gabriella; Klötzli, Urs S.

    2016-05-01

    The Permian Sesia Magmatic System of the southwestern Alps displays the plumbing system beneath a Permian caldera, including a deep crustal gabbroic complex, upper crustal granite plutons and a bimodal volcanic field dominated by rhyolitic tuff filling the caldera. Isotopic compositions of the deep crustal gabbro overlap those of coeval andesitic basalts, whereas granites define a distinct, more radiogenic cluster (Sri ≈ 0.708 and 0.710, respectively). AFC computations starting from the best mafic candidate for a starting melt show that Nd and Sr isotopic compositions and trace elements of andesitic basalts may be modeled by reactive bulk assimilation of ≈ 30% of partially depleted crust and ≈ 15%-30% gabbro fractionation. Trace elements of the deep crustal gabbro cumulates require a further ≈ 60% fractionation of the andesitic basalt and loss of ≈ 40% of silica-rich residual melt. The composition of the granite plutons is consistent with a mixture of relatively constant proportions of residual melt delivered from the gabbro and anatectic melt. Chemical and field evidence leads to a conceptual model which links the production of the two granitic components to the evolution of the Mafic Complex. During the growth of the Mafic Complex, progressive incorporation of packages of crustal rocks resulted in a roughly steady state rate of assimilation. Anatectic granite originates in the hot zone of melting crust located above the advancing mafic intrusion. Upward segregation of anatectic melts facilitates the assimilation of the partially depleted restite by stoping. At each cycle of mafic intrusion and incorporation, residual and anatectic melts are produced in roughly constant proportions, because the amount of anatectic melt produced at the roof is a function of volume and latent heat of crystallization of the underplated mafic melt which in turn produces proportional amounts of hybrid gabbro cumulates and residual melt. Such a process can explain the

  18. Advanced materials and methods for next generation spintronics

    NASA Astrophysics Data System (ADS)

    Siegel, Gene Phillip

    The modern age is filled with ever-advancing electronic devices. The contents of this dissertation continue the desire for faster, smaller, better electronics. Specifically, this dissertation addresses a field known as "spintronics", electronic devices based on an electron's spin, not just its charge. The field of spintronics originated in 1990 when Datta and Das first proposed a "spin transistor" that would function by passing a spin polarized current from a magnetic electrode into a semiconductor channel. The spins in the channel could then be manipulated by applying an electrical voltage across the gate of the device. However, it has since been found that a great amount of scattering occurs at the ferromagnet/semiconductor interface due to the large impedance mismatch that exists between the two materials. Because of this, there were three updated versions of the spintronic transistor that were proposed to improve spin injection: one that used a ferromagnetic semiconductor electrode, one that added a tunnel barrier between the ferromagnet and semiconductor, and one that utilized a ferromagnetic tunnel barrier which would act like a spin filter. It was next proposed that it may be possible to achieve a "pure spin current", or a spin current with no concurrent electric current (i.e., no net flow of electrons). One such method that was discovered is the spin Seebeck effect, which was discovered in 2008 by Uchida et al., in which a thermal gradient in a magnetic material generates a spin current which can be injected into adjacent material as a pure spin current. The first section of this dissertation addresses this spin Seebeck effect (SSE). The goal was to create such a device that both performs better than previously reported devices and is capable of operating without the aid of an external magnetic field. We were successful in this endeavor. The trick to achieving both of these goals was found to be in the roughness of the magnetic layer. A rougher magnetic

  19. Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions

    ERIC Educational Resources Information Center

    Syed, Mahbubur Rahman, Ed.

    2009-01-01

    The emerging field of advanced distance education delivers academic courses across time and distance, allowing educators and students to participate in a convenient learning method. "Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions" demonstrates communication technologies, intelligent…

  20. Negative Ion Density Fronts

    SciTech Connect

    Igor Kaganovich

    2000-12-18

    Negative ions tend to stratify in electronegative plasmas with hot electrons (electron temperature Te much larger than ion temperature Ti, Te > Ti ). The boundary separating a plasma containing negative ions, and a plasma, without negative ions, is usually thin, so that the negative ion density falls rapidly to zero-forming a negative ion density front. We review theoretical, experimental and numerical results giving the spatio-temporal evolution of negative ion density fronts during plasma ignition, the steady state, and extinction (afterglow). During plasma ignition, negative ion fronts are the result of the break of smooth plasma density profiles during nonlinear convection. In a steady-state plasma, the fronts are boundary layers with steepening of ion density profiles due to nonlinear convection also. But during plasma extinction, the ion fronts are of a completely different nature. Negative ions diffuse freely in the plasma core (no convection), whereas the negative ion front propagates towards the chamber walls with a nearly constant velocity. The concept of fronts turns out to be very effective in analysis of plasma density profile evolution in strongly non-isothermal plasmas.

  1. Firing up the front line.

    PubMed

    Katzenbach, J R; Santamaria, J A

    1999-01-01

    For many organizations, achieving competitive advantage means eliciting superior performance from employees on the front line--the burger flippers, hotel room cleaners, and baggage handlers whose work has an enormous effect on customers. That's no easy task. Front line workers are paid low wages, have scant hope of advancement, and--not surprisingly--often care little about the company's performance. But then how do some companies succeed in engaging the emotional energy of rank-and-file workers? A team of researchers at McKinsey & Company and the Conference Board recently explored that question and discovered that one highly effective route is demonstrated by the U.S. Marine Corps. The Marines' approach to motivation follows the "mission, values, and pride" path, which researchers say is practical and relevant for the business world. More specifically, the authors say the Marines follow five practices: they over-invest in cultivating core value; prepare every person to lead, including front line supervisors; learn when to create teams and when to create single-leader work groups; attend to all employees, not just the top half; and encourage self-discipline as a way of building pride. The authors admit there are critical differences between the Marines and most businesses. But using vivid examples from companies such as KFC and Marriott International, the authors illustrate how the Marines' approach can be translated for corporate use. Sometimes, the authors maintain, minor changes in a company's standard operating procedure can have a powerful effect on front line pride and can result in substantial payoffs in company performance.

  2. Domain decomposition by the advancing-partition method for parallel unstructured grid generation

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar Z. (Inventor); Banihashemi, legal representative, Soheila (Inventor)

    2012-01-01

    In a method for domain decomposition for generating unstructured grids, a surface mesh is generated for a spatial domain. A location of a partition plane dividing the domain into two sections is determined. Triangular faces on the surface mesh that intersect the partition plane are identified. A partition grid of tetrahedral cells, dividing the domain into two sub-domains, is generated using a marching process in which a front comprises only faces of new cells which intersect the partition plane. The partition grid is generated until no active faces remain on the front. Triangular faces on each side of the partition plane are collected into two separate subsets. Each subset of triangular faces is renumbered locally and a local/global mapping is created for each sub-domain. A volume grid is generated for each sub-domain. The partition grid and volume grids are then merged using the local-global mapping.

  3. Advanced 3D inverse method for designing turbomachine blades

    SciTech Connect

    Dang, T.

    1995-10-01

    To meet the goal of 60% plant-cycle efficiency or better set in the ATS Program for baseload utility scale power generation, several critical technologies need to be developed. One such need is the improvement of component efficiencies. This work addresses the issue of improving the performance of turbo-machine components in gas turbines through the development of an advanced three-dimensional and viscous blade design system. This technology is needed to replace some elements in current design systems that are based on outdated technology.

  4. Advancing digital methods in the fight against communicable diseases.

    PubMed

    Chabot-Couture, Guillaume; Seaman, Vincent Y; Wenger, Jay; Moonen, Bruno; Magill, Alan

    2015-03-01

    Important advances are being made in the fight against communicable diseases by using new digital tools. While they can be a challenge to deploy at-scale, GPS-enabled smartphones, electronic dashboards and computer models have multiple benefits. They can facilitate program operations, lead to new insights about the disease transmission and support strategic planning. Today, tools such as these are used to vaccinate more children against polio in Nigeria, reduce the malaria burden in Zambia and help predict the spread of the Ebola epidemic in West Africa.

  5. Classification methods for noise transients in advanced gravitational-wave detectors II: performance tests on Advanced LIGO data

    NASA Astrophysics Data System (ADS)

    Powell, Jade; Torres-Forné, Alejandro; Lynch, Ryan; Trifirò, Daniele; Cuoco, Elena; Cavaglià, Marco; Heng, Ik Siong; Font, José A.

    2017-02-01

    The data taken by the advanced LIGO and Virgo gravitational-wave detectors contains short duration noise transients that limit the significance of astrophysical detections and reduce the duty cycle of the instruments. As the advanced detectors are reaching sensitivity levels that allow for multiple detections of astrophysical gravitational-wave sources it is crucial to achieve a fast and accurate characterization of non-astrophysical transient noise shortly after it occurs in the detectors. Previously we presented three methods for the classification of transient noise sources. They are Principal Component Analysis for Transients (PCAT), Principal Component LALInference Burst (PC-LIB) and Wavelet Detection Filter with Machine Learning (WDF-ML). In this study we carry out the first performance tests of these algorithms on gravitational-wave data from the Advanced LIGO detectors. We use the data taken between the 3rd of June 2015 and the 14th of June 2015 during the 7th engineering run (ER7), and outline the improvements made to increase the performance and lower the latency of the algorithms on real data. This work provides an important test for understanding the performance of these methods on real, non stationary data in preparation for the second advanced gravitational-wave detector observation run, planned for later this year. We show that all methods can classify transients in non stationary data with a high level of accuracy and show the benefits of using multiple classifiers.

  6. Solidification fronts in supercooled liquids: how rapid fronts can lead to disordered glassy solids.

    PubMed

    Archer, A J; Robbins, M J; Thiele, U; Knobloch, E

    2012-09-01

    We determine the speed of a crystallization (or, more generally, a solidification) front as it advances into the uniform liquid phase after the system has been quenched into the crystalline region of the phase diagram. We calculate the front speed by assuming a dynamical density functional theory (DDFT) model for the system and applying a marginal stability criterion. Our results also apply to phase field crystal (PFC) models of solidification. As the solidification front advances into the unstable liquid phase, the density profile behind the advancing front develops density modulations and the wavelength of these modulations is a dynamically chosen quantity. For shallow quenches, the selected wavelength is precisely that of the crystalline phase and so well-ordered crystalline states are formed. However, when the system is deeply quenched, we find that this wavelength can be quite different from that of the crystal, so the solidification front naturally generates disorder in the system. Significant rearrangement and aging must subsequently occur for the system to form the regular well-ordered crystal that corresponds to the free energy minimum. Additional disorder is introduced whenever a front develops from random initial conditions. We illustrate these findings with simulation results obtained using the PFC model.

  7. Teaching Front Handsprings from a Developmental Approach

    ERIC Educational Resources Information Center

    Stork, Steve

    2006-01-01

    The front handspring is an important gymnastics skill that serves as a transition from beginner-level rolling and static balances to more advanced tumbling. It is, therefore, a skill highly desired by beginners. Early learning requires a great deal of effort during which students experience many failed attempts. Unless they are highly motivated,…

  8. Advanced methods of microscope control using μManager software

    PubMed Central

    Edelstein, Arthur D.; Tsuchida, Mark A.; Amodaj, Nenad; Pinkard, Henry; Vale, Ronald D.; Stuurman, Nico

    2014-01-01

    μManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, μManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced μManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging. PMID:25606571

  9. Comparison of Advanced Distillation Control Methods, Final Technical Report

    SciTech Connect

    Dr. James B. Riggs

    2000-11-30

    Detailed dynamic simulations of three industrial distillation columns (a propylene/propane splitter, a xylene/toluene column, and a depropanizer) have been used to evaluate configuration selections for single-ended and dual-composition control, as well as to compare conventional and advanced control approaches. In addition, a simulator of a main fractionator was used to compare the control performance of conventional and advanced control. For each case considered, the controllers were tuned by using setpoint changes and tested using feed composition upsets. Proportional Integral (PI) control performance was used to evaluate the configuration selection problem. For single ended control, the energy balance configuration was found to yield the best performance. For dual composition control, nine configurations were considered. It was determined that the use of dynamic simulations is required in order to identify the optimum configuration from among the nine possible choices. The optimum configurations were used to evaluate the relative control performance of conventional PI controllers, MPC (Model Predictive Control), PMBC (Process Model-Based Control), and ANN (Artificial Neural Networks) control. It was determined that MPC works best when one product is much more important than the other, while PI was superior when both products were equally important. PMBC and ANN were not found to offer significant advantages over PI and MPC. MPC was found to outperform conventional PI control for the main fractionator. MPC was applied to three industrial columns: one at Phillips Petroleum and two at Union Carbide. In each case, MPC was found to significantly outperform PI controls. The major advantage of the MPC controller is its ability to effectively handle a complex set of constraints and control objectives.

  10. An advanced deterministic method for spent fuel criticality safety analysis

    SciTech Connect

    DeHart, M.D.

    1998-01-01

    Over the past two decades, criticality safety analysts have come to rely to a large extent on Monte Carlo methods for criticality calculations. Monte Carlo has become popular because of its capability to model complex, non-orthogonal configurations or fissile materials, typical of real world problems. Over the last few years, however, interest in determinist transport methods has been revived, due shortcomings in the stochastic nature of Monte Carlo approaches for certain types of analyses. Specifically, deterministic methods are superior to stochastic methods for calculations requiring accurate neutron density distributions or differential fluxes. Although Monte Carlo methods are well suited for eigenvalue calculations, they lack the localized detail necessary to assess uncertainties and sensitivities important in determining a range of applicability. Monte Carlo methods are also inefficient as a transport solution for multiple pin depletion methods. Discrete ordinates methods have long been recognized as one of the most rigorous and accurate approximations used to solve the transport equation. However, until recently, geometric constraints in finite differencing schemes have made discrete ordinates methods impractical for non-orthogonal configurations such as reactor fuel assemblies. The development of an extended step characteristic (ESC) technique removes the grid structure limitations of traditional discrete ordinates methods. The NEWT computer code, a discrete ordinates code built upon the ESC formalism, is being developed as part of the SCALE code system. This paper will demonstrate the power, versatility, and applicability of NEWT as a state-of-the-art solution for current computational needs.

  11. Advances in rapid detection methods for foodborne pathogens.

    PubMed

    Zhao, Xihong; Lin, Chii-Wann; Wang, Jun; Oh, Deog Hwan

    2014-03-28

    Food safety is increasingly becoming an important public health issue, as foodborne diseases present a widespread and growing public health problem in both developed and developing countries. The rapid and precise monitoring and detection of foodborne pathogens are some of the most effective ways to control and prevent human foodborne infections. Traditional microbiological detection and identification methods for foodborne pathogens are well known to be time consuming and laborious as they are increasingly being perceived as insufficient to meet the demands of rapid food testing. Recently, various kinds of rapid detection, identification, and monitoring methods have been developed for foodborne pathogens, including nucleic-acid-based methods, immunological methods, and biosensor-based methods, etc. This article reviews the principles, characteristics, and applications of recent rapid detection methods for foodborne pathogens.

  12. Adherence to Scientific Method while Advancing Exposure Science

    EPA Science Inventory

    Paul Lioy was simultaneously a staunch adherent to the scientific method and an innovator of new ways to conduct science, particularly related to human exposure. Current challenges to science and the application of the scientific method are presented as they relate the approaches...

  13. Advances in validation, risk and uncertainty assessment of bioanalytical methods.

    PubMed

    Rozet, E; Marini, R D; Ziemons, E; Boulanger, B; Hubert, Ph

    2011-06-25

    Bioanalytical method validation is a mandatory step to evaluate the ability of developed methods to provide accurate results for their routine application in order to trust the critical decisions that will be made with them. Even if several guidelines exist to help perform bioanalytical method validations, there is still the need to clarify the meaning and interpretation of bioanalytical method validation criteria and methodology. Yet, different interpretations can be made of the validation guidelines as well as for the definitions of the validation criteria. This will lead to diverse experimental designs implemented to try fulfilling these criteria. Finally, different decision methodologies can also be interpreted from these guidelines. Therefore, the risk that a validated bioanalytical method may be unfit for its future purpose will depend on analysts personal interpretation of these guidelines. The objective of this review is thus to discuss and highlight several essential aspects of methods validation, not only restricted to chromatographic ones but also to ligand binding assays owing to their increasing role in biopharmaceutical industries. The points that will be reviewed are the common validation criteria, which are selectivity, standard curve, trueness, precision, accuracy, limits of quantification and range, dilutional integrity and analyte stability. Definitions, methodology, experimental design and decision criteria are reviewed. Two other points closely connected to method validation are also examined: incurred sample reproducibility testing and measurement uncertainty as they are highly linked to bioanalytical results reliability. Their additional implementation is foreseen to strongly reduce the risk of having validated a bioanalytical method unfit for its purpose.

  14. [Recent advances in sample preparation methods of plant hormones].

    PubMed

    Wu, Qian; Wang, Lus; Wu, Dapeng; Duan, Chunfeng; Guan, Yafeng

    2014-04-01

    Plant hormones are a group of naturally occurring trace substances which play a crucial role in controlling the plant development, growth and environment response. With the development of the chromatography and mass spectroscopy technique, chromatographic analytical method has become a widely used way for plant hormone analysis. Among the steps of chromatographic analysis, sample preparation is undoubtedly the most vital one. Thus, a highly selective and efficient sample preparation method is critical for accurate identification and quantification of phytohormones. For the three major kinds of plant hormones including acidic plant hormones & basic plant hormones, brassinosteroids and plant polypeptides, the sample preparation methods are reviewed in sequence especially the recently developed methods. The review includes novel methods, devices, extractive materials and derivative reagents for sample preparation of phytohormones analysis. Especially, some related works of our group are included. At last, the future developments in this field are also prospected.

  15. Advances in spectroscopic methods for quantifying soil carbon

    USGS Publications Warehouse

    Liebig, Mark; Franzluebbers, Alan J.; Follett, Ronald F.; Hively, W. Dean; Reeves, James B.; McCarty, Gregory W.; Calderon, Francisco

    2012-01-01

    The gold standard for soil C determination is combustion. However, this method requires expensive consumables, is limited to the determination of the total carbon and in the number of samples which can be processed (~100/d). With increased interest in soil C sequestration, faster methods are needed. Thus, interest in methods based on diffuse reflectance spectroscopy in the visible, near-infrared or mid-infrared ranges using either proximal or remote sensing. These methods have the ability to analyze more samples (2 to 3X/d) or huge areas (imagery) and do multiple analytes simultaneously, but require calibrations relating spectral and reference data and have specific problems, i.e., remote sensing is capable of scanning entire watersheds, thus reducing the sampling needed, but is limiting to the surface layer of tilled soils and by difficulty in obtaining proper calibration reference values. The objective of this discussion is the present state of spectroscopic methods for soil C determination.

  16. Advancements in frequency-domain methods for rotorcraft system identification

    NASA Technical Reports Server (NTRS)

    Tischler, Mark B.

    1989-01-01

    A new method for frequency-domain identification of rotorcraft dynamics is presented. Nonparametric frequency-response identification and parametric transfer-function modeling methods are extended to allow the extraction of state-space (stability and control derivative) representations. An interactive computer program DERIVID is described for the iterative solution of the multi-input/multi-output frequency-response matching approach used in the identification. Theoretical accuracy methods are used to determine the appropriate model structure and degree-of-confidence in the identified parameters. The method is applied to XV-15 tilt-rotor aircraft data in hover. Bare-airframe stability and control derivatives for the lateral/directional dynamics are shown to compare favorably with models previously obtained using time-domain identification methods and the XV-15 simulation program.

  17. Advancements in frequency-domain methods for rotorcraft system identification

    NASA Technical Reports Server (NTRS)

    Tischler, Mark B.

    1988-01-01

    A new method for frequency-domain identification of rotorcraft dynamics is presented. Nonparametric frequency-response identification and parametric tranfer-function modeling methods are extended to allow the extraction of state-space (stability and control derivative) representations. An interactive computer program DERIVID is described for the iterative solution of the multi-input/multi-output frequency-response matching approach used in the identification. Theoretical accuracy methods are used to determine the appropriate model structure and degree-of-confidence in the identified parameters. The method is applied to XV-15 tilt-rotor aircraft data in hover. Bare-airframe stability and control derivatives for the lateral/directional dynamics are shown to compare favorably with models previously obtained using time-domain identification methods and the XV-15 simulation program.

  18. Methods to Determine Recommended Feeder-Wide Advanced Inverter Settings for Improving Distribution System Performance

    SciTech Connect

    Rylander, Matthew; Reno, Matthew J.; Quiroz, Jimmy E.; Ding, Fei; Li, Huijuan; Broderick, Robert J.; Mather, Barry; Smith, Jeff

    2016-11-21

    This paper describes methods that a distribution engineer could use to determine advanced inverter settings to improve distribution system performance. These settings are for fixed power factor, volt-var, and volt-watt functionality. Depending on the level of detail that is desired, different methods are proposed to determine single settings applicable for all advanced inverters on a feeder or unique settings for each individual inverter. Seven distinctly different utility distribution feeders are analyzed to simulate the potential benefit in terms of hosting capacity, system losses, and reactive power attained with each method to determine the advanced inverter settings.

  19. Preface: Special Topic Section on Advanced Electronic Structure Methods for Solids and Surfaces

    SciTech Connect

    Michaelides, Angelos; Martinez, Todd J.; Alavi, Ali; Kresse, Georg

    2015-09-14

    This Special Topic section on Advanced Electronic Structure Methods for Solids and Surfaces contains a collection of research papers that showcase recent advances in the high accuracy prediction of materials and surface properties. It provides a timely snapshot of a growing field that is of broad importance to chemistry, physics, and materials science.

  20. Health, wealth, and air pollution: advancing theory and methods.

    PubMed Central

    O'Neill, Marie S; Jerrett, Michael; Kawachi, Ichiro; Levy, Jonathan I; Cohen, Aaron J; Gouveia, Nelson; Wilkinson, Paul; Fletcher, Tony; Cifuentes, Luis; Schwartz, Joel

    2003-01-01

    The effects of both ambient air pollution and socioeconomic position (SEP) on health are well documented. A limited number of recent studies suggest that SEP may itself play a role in the epidemiology of disease and death associated with exposure to air pollution. Together with evidence that poor and working-class communities are often more exposed to air pollution, these studies have stimulated discussion among scientists, policy makers, and the public about the differential distribution of the health impacts from air pollution. Science and public policy would benefit from additional research that integrates the theory and practice from both air pollution and social epidemiologies to gain a better understanding of this issue. In this article we aim to promote such research by introducing readers to methodologic and conceptual approaches in the fields of air pollution and social epidemiology; by proposing theories and hypotheses about how air pollution and socioeconomic factors may interact to influence health, drawing on studies conducted worldwide; by discussing methodologic issues in the design and analysis of studies to determine whether health effects of exposure to ambient air pollution are modified by SEP; and by proposing specific steps that will advance knowledge in this field, fill information gaps, and apply research results to improve public health in collaboration with affected communities. PMID:14644658

  1. Nuclear methods of analysis in the advanced neutron source

    SciTech Connect

    Robinson, L.; Dyer, F.F.

    1994-12-31

    The Advanced Neutron Source (ANS) research reactor is presently in the conceptual design phase. The thermal power of this heavy water cooled and moderated reactor will be about 350 megawatts. The core volume of 27 liter is designed to provide the optimum neutron fluence rate for the numerous experimental facilities. The peak thermal neutron fluence rate is expected to be slightly less than 10{sup 20} neutrons/m{sup 2}s. In addition to the more than 40 neutron scattering stations, there will be extensive facilities for isotope production, material irradiation and analytical chemistry including neutron activation analysis (NAA) and a slow positron source. The highlight of this reactor will be the capability that it will provide for conducting research using cold neutrons. Two cryostats containing helium-cooled liquid deuterium will be located in the heavy water reflector tank. Each cryostat will provide low-temperature neutrons to researchers via numerous guides. A hot source with two beam tubes and several thermal beam tubes will also be available. The NAA facilities in the ANS will consist of seven pneumatic tubes, one cold neutron guide for prompt gamma-ray neutron activation analysis (PGNAA), and one cold neutron slanted guide for neutron depth profiling (NDP). In addition to these neutron interrogation systems, a gamma-ray irradiation facility for materials testing will be housed in a spent fuel storage pool. This paper will provide detailed information regarding the design and use of these various experimental systems.

  2. The Saccharomyces Genome Database: Advanced Searching Methods and Data Mining.

    PubMed

    Cherry, J Michael

    2015-12-02

    At the core of the Saccharomyces Genome Database (SGD) are chromosomal features that encode a product. These include protein-coding genes and major noncoding RNA genes, such as tRNA and rRNA genes. The basic entry point into SGD is a gene or open-reading frame name that leads directly to the locus summary information page. A keyword describing function, phenotype, selective condition, or text from abstracts will also provide a door into the SGD. A DNA or protein sequence can be used to identify a gene or a chromosomal region using BLAST. Protein and DNA sequence identifiers, PubMed and NCBI IDs, author names, and function terms are also valid entry points. The information in SGD has been gathered and is maintained by a group of scientific biocurators and software developers who are devoted to providing researchers with up-to-date information from the published literature, connections to all the major research resources, and tools that allow the data to be explored. All the collected information cannot be represented or summarized for every possible question; therefore, it is necessary to be able to search the structured data in the database. This protocol describes the YeastMine tool, which provides an advanced search capability via an interactive tool. The SGD also archives results from microarray expression experiments, and a strategy designed to explore these data using the SPELL (Serial Pattern of Expression Levels Locator) tool is provided.

  3. Advanced scanning methods with tracking optical coherence tomography

    PubMed Central

    Ferguson, R. Daniel; Iftimia, Nicusor V.; Ustun, Teoman; Wollstein, Gadi; Ishikawa, Hiroshi; Gabriele, Michelle L.; Dilworth, William D.; Kagemann, Larry; Schuman, Joel S.

    2013-01-01

    An upgraded optical coherence tomography system with integrated retinal tracker (TOCT) was developed. The upgraded system uses improved components to extend the tracking bandwidth, fully integrates the tracking hardware into the optical head of the clinical OCT system, and operates from a single software platform. The system was able to achieve transverse scan registration with sub-pixel accuracy (~10 μm). We demonstrate several advanced scan sequences with the TOCT, including composite scans averaged (co-added) from multiple B-scans taken consecutively and several hours apart, en face images collected by summing the A-scans of circular, line, and raster scans, and three-dimensional (3D) retinal maps of the fovea and optic disc. The new system achieves highly accurate OCT scan registration yielding composite images with significantly improved spatial resolution, increased signal-to-noise ratio, and reduced speckle while maintaining well-defined boundaries and sharp fine structure compared to single scans. Precise re-registration of multiple scans over separate imaging sessions demonstrates TOCT utility for longitudinal studies. En face images and 3D data cubes generated from these data reveal high fidelity image registration with tracking, despite scan durations of more than one minute. PMID:19498823

  4. Review: Advances in delta-subsidence research using satellite methods

    NASA Astrophysics Data System (ADS)

    Higgins, Stephanie A.

    2016-05-01

    Most of the world's major river deltas are sinking relative to local sea level. The effects of subsidence can include aquifer salinization, infrastructure damage, increased vulnerability to flooding and storm surges, and permanent inundation of low-lying land. Consequently, determining the relative importance of natural vs. anthropogenic pressures in driving delta subsidence is a topic of ongoing research. This article presents a review of knowledge with respect to delta surface-elevation loss. The field is rapidly advancing due to applications of space-based techniques: InSAR (interferometric synthetic aperture radar), GPS (global positioning system), and satellite ocean altimetry. These techniques have shed new light on a variety of subsidence processes, including tectonics, isostatic adjustment, and the spatial and temporal variability of sediment compaction. They also confirm that subsidence associated with fluid extraction can outpace sea-level rise by up to two orders of magnitude, resulting in effective sea-level rise that is one-hundred times faster than the global average rate. In coming years, space-based and airborne instruments will be critical in providing near-real-time monitoring to facilitate management decisions in sinking deltas. However, ground-based observations continue to be necessary for generating complete measurements of surface-elevation change. Numerical modeling should seek to simulate couplings between subsidence processes for greater predictive power.

  5. Prediction of Dynamic Stall Characteristics Using Advanced Nonlinear Panel Methods,

    DTIC Science & Technology

    This paper presents preliminary results of work in which a surface singularity panel method is being extended for modelling the dynamic interaction...between a separated wake and a surface undergoing an unsteady motion. The method combines the capabilities of an unsteady time-stepping code and a... technique for modelling extensive separation using free vortex sheets. Routines are developed for treating the dynamic interaction between the separated

  6. Advances in spectroscopic methods for quantifying soil carbon

    USGS Publications Warehouse

    Reeves, James B.; McCarty, Gregory W.; Calderon, Francisco; Hively, W. Dean

    2012-01-01

    The current gold standard for soil carbon (C) determination is elemental C analysis using dry combustion. However, this method requires expensive consumables, is limited by the number of samples that can be processed (~100/d), and is restricted to the determination of total carbon. With increased interest in soil C sequestration, faster methods of analysis are needed, and there is growing interest in methods based on diffuse reflectance spectroscopy in the visible, near-infrared or mid-infrared spectral ranges. These spectral methods can decrease analytical requirements and speed sample processing, be applied to large landscape areas using remote sensing imagery, and be used to predict multiple analytes simultaneously. However, the methods require localized calibrations to establish the relationship between spectral data and reference analytical data, and also have additional, specific problems. For example, remote sensing is capable of scanning entire watersheds for soil carbon content but is limited to the surface layer of tilled soils and may require difficult and extensive field sampling to obtain proper localized calibration reference values. The objective of this chapter is to discuss the present state of spectroscopic methods for determination of soil carbon.

  7. The advance of non-invasive detection methods in osteoarthritis

    NASA Astrophysics Data System (ADS)

    Dai, Jiao; Chen, Yanping

    2011-06-01

    Osteoarthritis (OA) is one of the most prevalent chronic diseases which badly affected the patients' living quality and economy. Detection and evaluation technology can provide basic information for early treatment. A variety of imaging methods in OA were reviewed, such as conventional X-ray, computed tomography (CT), ultrasound (US), magnetic resonance imaging (MRI) and near-infrared spectroscopy (NIRS). Among the existing imaging modalities, the spatial resolution of X-ray is extremely high; CT is a three-dimensional method, which has high density resolution; US as an evaluation method of knee OA discriminates lesions sensitively between normal cartilage and degenerative one; as a sensitive and nonionizing method, MRI is suitable for the detection of early OA, but the cost is too expensive for routine use; NIRS is a safe, low cost modality, and is also good at detecting early stage OA. In a word, each method has its own advantages, but NIRS is provided with broader application prospect, and it is likely to be used in clinical daily routine and become the golden standard for diagnostic detection.

  8. Application of advanced reliability methods to local strain fatigue analysis

    NASA Technical Reports Server (NTRS)

    Wu, T. T.; Wirsching, P. H.

    1983-01-01

    When design factors are considered as random variables and the failure condition cannot be expressed by a closed form algebraic inequality, computations of risk (or probability of failure) might become extremely difficult or very inefficient. This study suggests using a simple, and easily constructed, second degree polynomial to approximate the complicated limit state in the neighborhood of the design point; a computer analysis relates the design variables at selected points. Then a fast probability integration technique (i.e., the Rackwitz-Fiessler algorithm) can be used to estimate risk. The capability of the proposed method is demonstrated in an example of a low cycle fatigue problem for which a computer analysis is required to perform local strain analysis to relate the design variables. A comparison of the performance of this method is made with a far more costly Monte Carlo solution. Agreement of the proposed method with Monte Carlo is considered to be good.

  9. Protein Microarrays with Novel Microfluidic Methods: Current Advances.

    PubMed

    Dixit, Chandra K; Aguirre, Gerson R

    2014-07-01

    Microfluidic-based micromosaic technology has allowed the pattering of recognition elements in restricted micrometer scale areas with high precision. This controlled patterning enabled the development of highly multiplexed arrays multiple analyte detection. This arraying technology was first introduced in the beginning of 2001 and holds tremendous potential to revolutionize microarray development and analyte detection. Later, several microfluidic methods were developed for microarray application. In this review we discuss these novel methods and approaches which leverage the property of microfluidic technologies to significantly improve various physical aspects of microarray technology, such as enhanced imprinting homogeneity, stability of the immobilized biomolecules, decreasing assay times, and reduction of the costs and of the bulky instrumentation.

  10. Advances in dual algorithms and convex approximation methods

    NASA Technical Reports Server (NTRS)

    Smaoui, H.; Fleury, C.; Schmit, L. A.

    1988-01-01

    A new algorithm for solving the duals of separable convex optimization problems is presented. The algorithm is based on an active set strategy in conjunction with a variable metric method. This first order algorithm is more reliable than Newton's method used in DUAL-2 because it does not break down when the Hessian matrix becomes singular or nearly singular. A perturbation technique is introduced in order to remove the nondifferentiability of the dual function which arises when linear constraints are present in the approximate problem.

  11. A CTSA agenda to advance methods for comparative effectiveness research.

    PubMed

    Helfand, Mark; Tunis, Sean; Whitlock, Evelyn P; Pauker, Stephen G; Basu, Anirban; Chilingerian, Jon; Harrell, Frank E; Meltzer, David O; Montori, Victor M; Shepard, Donald S; Kent, David M

    2011-06-01

    Clinical research needs to be more useful to patients, clinicians, and other decision makers. To meet this need, more research should focus on patient-centered outcomes, compare viable alternatives, and be responsive to individual patients' preferences, needs, pathobiology, settings, and values. These features, which make comparative effectiveness research (CER) fundamentally patient-centered, challenge researchers to adopt or develop methods that improve the timeliness, relevance, and practical application of clinical studies. In this paper, we describe 10 priority areas that address 3 critical needs for research on patient-centered outcomes (PCOR): (1) developing and testing trustworthy methods to identify and prioritize important questions for research; (2) improving the design, conduct, and analysis of clinical research studies; and (3) linking the process and outcomes of actual practice to priorities for research on patient-centered outcomes. We argue that the National Institutes of Health, through its clinical and translational research program, should accelerate the development and refinement of methods for CER by linking a program of methods research to the broader portfolio of large, prospective clinical and health system studies it supports. Insights generated by this work should be of enormous value to PCORI and to the broad range of organizations that will be funding and implementing CER.

  12. Advanced Methods for the Solution of Differential Equations.

    ERIC Educational Resources Information Center

    Goldstein, Marvin E.; Braun, Willis H.

    This is a textbook, originally developed for scientists and engineers, which stresses the actual solutions of practical problems. Theorems are precisely stated, but the proofs are generally omitted. Sample contents include first-order equations, equations in the complex plane, irregular singular points, and numerical methods. A more recent idea,…

  13. Origins, Methods and Advances in Qualitative Meta-Synthesis

    ERIC Educational Resources Information Center

    Nye, Elizabeth; Melendez-Torres, G. J.; Bonell, Chris

    2016-01-01

    Qualitative research is a broad term encompassing many methods. Critiques of the field of qualitative research argue that while individual studies provide rich descriptions and insights, the absence of connections drawn between studies limits their usefulness. In response, qualitative meta-synthesis serves as a design to interpret and synthesise…

  14. Generalized Weighted Residual Method; Advancements and Current Studies

    NASA Astrophysics Data System (ADS)

    Scheffel, Jan; Lindvall, Kristoffer

    2016-10-01

    The Generalized Weighted Residual Method (GWRM) is a time-spectral method for solving initial value partial differential equations. The GWRM treats the temporal, spatial, and parameter domains by projecting the residual to a Chebyshev polynomial space, with the variational principle being that the residual is zero. This treatment provides a global semi-analytical solution. However, straightforward global solution is not economical. One remedy is the inclusion of spatial and temporal sub-domains with coupled internal boundary conditions, which decreases memory requirements and introduces sparse matrices. Only the equations pertaining to the boundary conditions need be solved globally, making the method parallelizable in time. Efficient solution of the linearized ideal MHD stability equations of screw-pinch equilibria are proved possible. The GWRM has also been used to solve strongly nonlinear ODEs such as the Lorenz equations (1984), and is capable of competing with finite time difference schemes in terms of both accuracy and efficiency. GWRM solutions of linear and nonlinear model problems of interest for stability and turbulence modelling will be presented, including detailed comparisons with time stepping methods.

  15. A modified captive bubble method for determining advancing and receding contact angles

    NASA Astrophysics Data System (ADS)

    Xue, Jian; Shi, Pan; Zhu, Lin; Ding, Jianfu; Chen, Qingmin; Wang, Qingjun

    2014-03-01

    In this work, a modification to the captive bubble method was proposed to test the advancing and receding contact angle. This modification is done by adding a pressure chamber with a pressure control system to the original experimental system equipped with an optical angle mater equipped with a high speed CCD camera, a temperature control system and a computer. A series of samples with highly hydrophilic, hydrophilic, hydrophobic and superhydrophobic surfaces were prepared. The advancing and receding contact angles of these samples with highly hydrophilic, hydrophilic, and hydrophobic surfaces through the new methods was comparable to the result tested by the traditional sessile drop method. It is proved that this method overcomes the limitation of the traditional captive bubble method and the modified captive bubble method allows a smaller error from the test. However, due to the nature of the captive bubble technique, this method is also only suitable for testing the surface with advancing or receding contact angle below 130°.

  16. Advanced discretizations and multigrid methods for liquid crystal configurations

    NASA Astrophysics Data System (ADS)

    Emerson, David B.

    Liquid crystals are substances that possess mesophases with properties intermediate between liquids and crystals. Here, we consider nematic liquid crystals, which consist of rod-like molecules whose average pointwise orientation is represented by a unit-length vector, n( x, y, z) = (n1, n 2, n3)T. In addition to their self-structuring properties, nematics are dielectrically active and birefringent. These traits continue to lead to many important applications and discoveries. Numerical simulations of liquid crystal configurations are used to suggest the presence of new physical phenomena, analyze experiments, and optimize devices. This thesis develops a constrained energy-minimization finite-element method for the efficient computation of nematic liquid crystal equilibrium configurations based on a Lagrange multiplier formulation and the Frank-Oseen free-elastic energy model. First-order optimality conditions are derived and linearized via a Newton approach, yielding a linear system of equations. Due to the nonlinear unit-length constraint, novel well-posedness theory for the variational systems, as well as error analysis, is conducted. The approach is shown to constitute a convergent and well-posed approach, absent typical simplifying assumptions. Moreover, the energy-minimization method and well-posedness theory developed for the free-elastic case are extended to include the effects of applied electric fields and flexoelectricity. In the computational algorithm, nested iteration is applied and proves highly effective at reducing computational costs. Additionally, an alternative technique is studied, where the unit-length constraint is imposed by a penalty method. The performance of the penalty and Lagrange multiplier methods is compared. Furthermore, tailored trust-region strategies are introduced to improve robustness and efficiency. While both approaches yield effective algorithms, the Lagrange multiplier method demonstrates superior accuracy per unit cost. In

  17. Advanced Physical Models and Numerical Methods for High Enthalpy and Plasma Flows Applied to Hypersonics

    DTIC Science & Technology

    2011-07-28

    nonequilibrium. For example, the plasma transport may transition between rarefied and continuum flow , requiring appropriate models for each case through...AFRL-AFOSR-UK-TR-2011-0023 Advanced Physical Models and Numerical Methods for High Enthalpy and Plasma Flows Applied to Hypersonics...2010 4. TITLE AND SUBTITLE Advanced Physical Models and Numerical Methods for High Enthalpy and Plasma Flows Applied to Hypersonics 5a

  18. Protein Microarrays with Novel Microfluidic Methods: Current Advances

    PubMed Central

    Dixit, Chandra K.; Aguirre, Gerson R.

    2014-01-01

    Microfluidic-based micromosaic technology has allowed the pattering of recognition elements in restricted micrometer scale areas with high precision. This controlled patterning enabled the development of highly multiplexed arrays multiple analyte detection. This arraying technology was first introduced in the beginning of 2001 and holds tremendous potential to revolutionize microarray development and analyte detection. Later, several microfluidic methods were developed for microarray application. In this review we discuss these novel methods and approaches which leverage the property of microfluidic technologies to significantly improve various physical aspects of microarray technology, such as enhanced imprinting homogeneity, stability of the immobilized biomolecules, decreasing assay times, and reduction of the costs and of the bulky instrumentation. PMID:27600343

  19. Numerical modeling of spray combustion with an advanced VOF method

    NASA Technical Reports Server (NTRS)

    Chen, Yen-Sen; Shang, Huan-Min; Shih, Ming-Hsin; Liaw, Paul

    1995-01-01

    This paper summarizes the technical development and validation of a multiphase computational fluid dynamics (CFD) numerical method using the volume-of-fluid (VOF) model and a Lagrangian tracking model which can be employed to analyze general multiphase flow problems with free surface mechanism. The gas-liquid interface mass, momentum and energy conservation relationships are modeled by continuum surface mechanisms. A new solution method is developed such that the present VOF model can be applied for all-speed flow regimes. The objectives of the present study are to develop and verify the fractional volume-of-fluid cell partitioning approach into a predictor-corrector algorithm and to demonstrate the effectiveness of the present approach by simulating benchmark problems including laminar impinging jets, shear coaxial jet atomization and shear coaxial spray combustion flows.

  20. Advanced hydraulic fracturing methods to create in situ reactive barriers

    SciTech Connect

    Murdoch, L. |; Siegrist, B.; Meiggs, T.

    1997-12-31

    This article describes the use of hydraulic fracturing to increase permeability in geologic formations where in-situ remedial action of contaminant plumes will be performed. Several in-situ treatment strategies are discussed including the use of hydraulic fracturing to create in situ redox zones for treatment of organics and inorganics. Hydraulic fracturing methods offer a mechanism for the in-situ treatment of gently dipping layers of reactive compounds. Specialized methods using real-time monitoring and a high-energy jet during fracturing allow the form of the fracture to be influenced, such as creation of assymmetric fractures beneath potential sources (i.e. tanks, pits, buildings) that should not be penetrated by boring. Some examples of field applications of this technique such as creating fractures filled with zero-valent iron to reductively dechlorinate halogenated hydrocarbons, and the use of granular activated carbon to adsorb compounds are discussed.

  1. Advanced hybrid particulate collector and method of operation

    DOEpatents

    Miller, Stanley J.

    2003-04-08

    A device and method for controlling particulate air pollutants of the present invention combines filtration and electrostatic collection devices. The invention includes a chamber housing a plurality of rows of filter elements. Between the rows of filter elements are rows of high voltage discharge electrodes. Between the rows of discharge electrodes and the rows of filter elements are grounded perforated plates for creating electrostatic precipitation zones.

  2. Advanced Numerical Methods for Computing Statistical Quantities of Interest

    DTIC Science & Technology

    2014-07-10

    coefficients , forcing terms, and initial conditions was analyzed. The input data were assumed to depend on a finite number of random variables . Unlike...89, 2012, 1269-1280. We considered the Musiela equation of forward rates; this is a hyperbolic stochastic partial differential equation . A weak...ZHANG AND M. GUNZBURGER, Error analysis of stochastic collocation method for parabolic partial differential equations with random input data; SIAM Journal

  3. Advanced and In Situ Analytical Methods for Solar Fuel Materials.

    PubMed

    Chan, Candace K; Tüysüz, Harun; Braun, Artur; Ranjan, Chinmoy; La Mantia, Fabio; Miller, Benjamin K; Zhang, Liuxian; Crozier, Peter A; Haber, Joel A; Gregoire, John M; Park, Hyun S; Batchellor, Adam S; Trotochaud, Lena; Boettcher, Shannon W

    2016-01-01

    In situ and operando techniques can play important roles in the development of better performing photoelectrodes, photocatalysts, and electrocatalysts by helping to elucidate crucial intermediates and mechanistic steps. The development of high throughput screening methods has also accelerated the evaluation of relevant photoelectrochemical and electrochemical properties for new solar fuel materials. In this chapter, several in situ and high throughput characterization tools are discussed in detail along with their impact on our understanding of solar fuel materials.

  4. Evaluation of pediatric manual wheelchair mobility using advanced biomechanical methods.

    PubMed

    Slavens, Brooke A; Schnorenberg, Alyssa J; Aurit, Christine M; Graf, Adam; Krzak, Joseph J; Reiners, Kathryn; Vogel, Lawrence C; Harris, Gerald F

    2015-01-01

    There is minimal research of upper extremity joint dynamics during pediatric wheelchair mobility despite the large number of children using manual wheelchairs. Special concern arises with the pediatric population, particularly in regard to the longer duration of wheelchair use, joint integrity, participation and community integration, and transitional care into adulthood. This study seeks to provide evaluation methods for characterizing the biomechanics of wheelchair use by children with spinal cord injury (SCI). Twelve subjects with SCI underwent motion analysis while they propelled their wheelchair at a self-selected speed and propulsion pattern. Upper extremity joint kinematics, forces, and moments were computed using inverse dynamics methods with our custom model. The glenohumeral joint displayed the largest average range of motion (ROM) at 47.1° in the sagittal plane and the largest average superiorly and anteriorly directed joint forces of 6.1% BW and 6.5% BW, respectively. The largest joint moments were 1.4% body weight times height (BW × H) of elbow flexion and 1.2% BW × H of glenohumeral joint extension. Pediatric manual wheelchair users demonstrating these high joint demands may be at risk for pain and upper limb injuries. These evaluation methods may be a useful tool for clinicians and therapists for pediatric wheelchair prescription and training.

  5. Recent advances in sample preparation techniques for effective bioanalytical methods.

    PubMed

    Kole, Prashant Laxman; Venkatesh, Gantala; Kotecha, Jignesh; Sheshala, Ravi

    2011-01-01

    This paper reviews the recent developments in bioanalysis sample preparation techniques and gives an update on basic principles, theory, applications and possibilities for automation, and a comparative discussion on the advantages and limitation of each technique. Conventional liquid-liquid extraction (LLE), protein precipitation (PP) and solid-phase extraction (SPE) techniques are now been considered as methods of the past. The last decade has witnessed a rapid development of novel sample preparation techniques in bioanalysis. Developments in SPE techniques such as selective sorbents and in the overall approach to SPE, such as hybrid SPE and molecularly imprinted polymer SPE, have been addressed. Considerable literature has been published in the area of solid-phase micro-extraction and its different versions, e.g. stir bar sorptive extraction, and their application in the development of selective and sensitive bioanalytical methods. Techniques such as dispersive solid-phase extraction, disposable pipette extraction and micro-extraction by packed sorbent offer a variety of extraction phases and provide unique advantages to bioanalytical methods. On-line SPE utilizing column-switching techniques is rapidly gaining acceptance in bioanalytical applications. PP sample preparation techniques such as PP filter plates/tubes offer many advantages like removal of phospholipids and proteins in plasma/serum. Newer approaches to conventional LLE techniques (salting-out LLE) are also covered in this review article.

  6. Advances in multifocal methods for imaging human brain activity

    NASA Astrophysics Data System (ADS)

    Carney, Thom; Ales, Justin; Klein, Stanley A.

    2006-02-01

    The typical multifocal stimulus used in visual evoked potential (VEP) studies consists of about 60 checkerboard stimulus patches each independently contrast reversed according to an m-sequence. Cross correlation of the response (EEG, MEG, ERG, or fMRI) with the m-sequence results in a series of response kernels for each response channel and each stimulus patch. In the past the number and complexity of stimulus patches has been constrained by graphics hardware, namely the use of look-up-table (LUT) animation methods. To avoid such limitations we replaced the LUTs with true color graphic sprites to present arbitrary spatial patterns. To demonstrate the utility of the method we have recorded simultaneously from 192 cortically scaled stimulus patches each of which activate about 12mm2 of cortex in area V1. Because of the sparseness of cortical folding, very small stimulus patches and robust estimation of dipole source orientation, the method opens a new window on precise spatio-temporal mapping of early visual areas. The use of sprites also enables multiplexing stimuli such that at each patch location multiple stimuli can be presented. We have presented patterns with different orientations (or spatial frequencies) at the same patch locations but independently temporally modulated, effectively doubling the number of stimulus patches, to explore cell population interactions at the same cortical locus. We have also measured nonlinear responses to adjacent pairs of patches, thereby getting an edge response that doubles the spatial sampling density to about 1.8 mm on cortex.

  7. Advanced physical models and monitoring methods for in situ bioremediation

    SciTech Connect

    Simon, K.; Chalmer, P.

    1996-05-30

    Numerous reports have indicated that contamination at DOE facilities is widespread and pervasive. Existing technology is often too costly or ineffective in remediating these contamination problems. An effective method to address one class of contamination, petroleum hydrocarbons, is in situ bioremediation. This project was designed to provide tools and approaches for increasing the reliability of in situ bioremediation. An example of the recognition within DOE for developing these tools is in the FY-1995 Technology Development Needs Summary of the Office of Technology Development of the US DOE. This document identifies specific needs addressed by this research. For example, Section 3.3 Need Statement IS-3 identifies the need for a {open_quotes}Rapid method to detect in situ biodegradation products.{close_quotes} Also, BW-I identifies the need to recognize boundaries between clean and contaminated materials and soils. Metabolic activity could identify these boundaries. Measuring rates of in situ microbial activity is critical to the fundamental understanding of subsurface microbiology and in selecting natural attenuation as a remediation option. Given the complexity and heterogeneity of subsurface environments, a significant cost incurred during bioremediation is the characterization of microbial activity, in part because so many intermediate end points (biomass, gene frequency, laboratory measurements of activity, etc.) must be used to infer in situ activity. A fast, accurate, real-time, and cost-effective method is needed to determine success of bioremediation at DOE sites.

  8. Advanced numerical methods and software approaches for semiconductor device simulation

    SciTech Connect

    CAREY,GRAHAM F.; PARDHANANI,A.L.; BOVA,STEVEN W.

    2000-03-23

    In this article the authors concisely present several modern strategies that are applicable to drift-dominated carrier transport in higher-order deterministic models such as the drift-diffusion, hydrodynamic, and quantum hydrodynamic systems. The approaches include extensions of upwind and artificial dissipation schemes, generalization of the traditional Scharfetter-Gummel approach, Petrov-Galerkin and streamline-upwind Petrov Galerkin (SUPG), entropy variables, transformations, least-squares mixed methods and other stabilized Galerkin schemes such as Galerkin least squares and discontinuous Galerkin schemes. The treatment is representative rather than an exhaustive review and several schemes are mentioned only briefly with appropriate reference to the literature. Some of the methods have been applied to the semiconductor device problem while others are still in the early stages of development for this class of applications. They have included numerical examples from the recent research tests with some of the methods. A second aspect of the work deals with algorithms that employ unstructured grids in conjunction with adaptive refinement strategies. The full benefits of such approaches have not yet been developed in this application area and they emphasize the need for further work on analysis, data structures and software to support adaptivity. Finally, they briefly consider some aspects of software frameworks. These include dial-an-operator approaches such as that used in the industrial simulator PROPHET, and object-oriented software support such as those in the SANDIA National Laboratory framework SIERRA.

  9. Advanced Numerical Methods and Software Approaches for Semiconductor Device Simulation

    DOE PAGES

    Carey, Graham F.; Pardhanani, A. L.; Bova, S. W.

    2000-01-01

    In this article we concisely present several modern strategies that are applicable to driftdominated carrier transport in higher-order deterministic models such as the driftdiffusion, hydrodynamic, and quantum hydrodynamic systems. The approaches include extensions of “upwind” and artificial dissipation schemes, generalization of the traditional Scharfetter – Gummel approach, Petrov – Galerkin and streamline-upwind Petrov Galerkin (SUPG), “entropy” variables, transformations, least-squares mixed methods and other stabilized Galerkin schemes such as Galerkin least squares and discontinuous Galerkin schemes. The treatment is representative rather than an exhaustive review and several schemes are mentioned only briefly with appropriate reference to the literature. Some of themore » methods have been applied to the semiconductor device problem while others are still in the early stages of development for this class of applications. We have included numerical examples from our recent research tests with some of the methods. A second aspect of the work deals with algorithms that employ unstructured grids in conjunction with adaptive refinement strategies. The full benefits of such approaches have not yet been developed in this application area and we emphasize the need for further work on analysis, data structures and software to support adaptivity. Finally, we briefly consider some aspects of software frameworks. These include dial-an-operator approaches such as that used in the industrial simulator PROPHET, and object-oriented software support such as those in the SANDIA National Laboratory framework SIERRA.« less

  10. Light-Front Holography and the Light-Front Schrodinger Equation

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy

    2012-08-15

    One of the most important nonperturbative methods for solving QCD is quantization at fixed light-front time {tau} = t+z=c - Dirac's 'Front Form'. The eigenvalues of the light-front QCD Hamiltonian predict the hadron spectrum and the eigensolutions provide the light-front wavefunctions which describe hadron structure. More generally, we show that the valence Fock-state wavefunctions of the light-front QCD Hamiltonian satisfy a single-variable relativistic equation of motion, analogous to the nonrelativistic radial Schrodinger equation, with an effective confining potential U which systematically incorporates the effects of higher quark and gluon Fock states. We outline a method for computing the required potential from first principles in QCD. The holographic mapping of gravity in AdS space to QCD, quantized at fixed light-front time, yields the same light front Schrodinger equation; in fact, the soft-wall AdS/QCD approach provides a model for the light-front potential which is color-confining and reproduces well the light-hadron spectrum. One also derives via light-front holography a precise relation between the bound-state amplitudes in the fifth dimension of AdS space and the boost-invariant light-front wavefunctions describing the internal structure of hadrons in physical space-time. The elastic and transition form factors of the pion and the nucleons are found to be well described in this framework. The light-front AdS/QCD holographic approach thus gives a frame-independent first approximation of the color-confining dynamics, spectroscopy, and excitation spectra of relativistic light-quark bound states in QCD.

  11. Advances in Laboratory Methods for Detection and Typing of Norovirus

    PubMed Central

    2014-01-01

    Human noroviruses are the leading cause of epidemic and sporadic gastroenteritis across all age groups. Although the disease is usually self-limiting, in the United States norovirus gastroenteritis causes an estimated 56,000 to 71,000 hospitalizations and 570 to 800 deaths each year. This minireview describes the latest data on laboratory methods (molecular, immunological) for norovirus detection, including real-time reverse transcription-quantitative PCR (RT-qPCR) and commercially available immunological assays as well as the latest FDA-cleared multi-gastrointestinal-pathogen platforms. In addition, an overview is provided on the latest nomenclature and molecular epidemiology of human noroviruses. PMID:24989606

  12. Advanced Signal Processing Methods Applied to Digital Mammography

    NASA Technical Reports Server (NTRS)

    Stauduhar, Richard P.

    1997-01-01

    The work reported here is on the extension of the earlier proposal of the same title, August 1994-June 1996. The report for that work is also being submitted. The work reported there forms the foundation for this work from January 1997 to September 1997. After the earlier work was completed there were a few items that needed to be completed prior to submission of a new and more comprehensive proposal for further research. Those tasks have been completed and two new proposals have been submitted, one to NASA, and one to Health & Human Services WS). The main purpose of this extension was to refine some of the techniques that lead to automatic large scale evaluation of full mammograms. Progress on each of the proposed tasks follows. Task 1: A multiresolution segmentation of background from breast has been developed and tested. The method is based on the different noise characteristics of the two different fields. The breast field has more power in the lower octaves and the off-breast field behaves similar to a wideband process, where more power is in the high frequency octaves. After the two fields are separated by lowpass filtering, a region labeling routine is used to find the largest contiguous region, the breast. Task 2: A wavelet expansion that can decompose the image without zero padding has been developed. The method preserves all properties of the power-of-two wavelet transform and does not add appreciably to computation time or storage. This work is essential for analysis of the full mammogram, as opposed to selecting sections from the full mammogram. Task 3: A clustering method has been developed based on a simple counting mechanism. No ROC analysis has been performed (and was not proposed), so we cannot finally evaluate this work without further support. Task 4: Further testing of the filter reveals that different wavelet bases do yield slightly different qualitative results. We cannot provide quantitative conclusions about this for all possible bases

  13. Human body composition: advances in models and methods.

    PubMed

    Heymsfield, S B; Wang, Z; Baumgartner, R N; Ross, R

    1997-01-01

    The field of human body composition research is reaching a mature stage in its development: The three interconnected areas that define body composition research--models and their rules, methodology, and biological effects--are well-defined and are actively investigated by scientists in diverse disciplines from many different nations; and methods are available for measuring all major atomic, molecular, cellular, and tissue-system level body composition components in research, clinical, and epidemiological settings. This review summarizes main body composition research concepts, examines new component-measurement methodologies, and identifies potential areas of future research.

  14. Advanced hybrid particulate collector and method of operation

    DOEpatents

    Miller, Stanley J.

    1999-01-01

    A device and method for controlling particulate air pollutants of the present invention combines filtration and electrostatic collection devices. The invention includes a chamber housing a plurality of rows of filter elements. Between each row of filter elements is a grounded plate. Between the grounded plates and the filter elements are electrode grids for creating electrostatic precipitation zones between each row of filter elements. In this way, when the filter elements are cleaned by pulsing air in a reverse direction, the dust removed from the bags will collect in the electrostatic precipitation zones rather than on adjacent filter elements.

  15. Advanced hybrid particulate collector and method of operation

    DOEpatents

    Miller, S.J.

    1999-08-17

    A device and method for controlling particulate air pollutants of the present invention combines filtration and electrostatic collection devices. The invention includes a chamber housing a plurality of rows of filter elements. Between each row of filter elements is a grounded plate. Between the grounded plates and the filter elements are electrode grids for creating electrostatic precipitation zones between each row of filter elements. In this way, when the filter elements are cleaned by pulsing air in a reverse direction, the dust removed from the bags will collect in the electrostatic precipitation zones rather than on adjacent filter elements. 12 figs.

  16. Advanced Computational Aeroacoustics Methods for Fan Noise Prediction

    NASA Technical Reports Server (NTRS)

    Envia, Edmane (Technical Monitor); Tam, Christopher

    2003-01-01

    Direct computation of fan noise is presently not possible. One of the major difficulties is the geometrical complexity of the problem. In the case of fan noise, the blade geometry is critical to the loading on the blade and hence the intensity of the radiated noise. The precise geometry must be incorporated into the computation. In computational fluid dynamics (CFD), there are two general ways to handle problems with complex geometry. One way is to use unstructured grids. The other is to use body fitted overset grids. In the overset grid method, accurate data transfer is of utmost importance. For acoustic computation, it is not clear that the currently used data transfer methods are sufficiently accurate as not to contaminate the very small amplitude acoustic disturbances. In CFD, low order schemes are, invariably, used in conjunction with unstructured grids. However, low order schemes are known to be numerically dispersive and dissipative. dissipative errors are extremely undesirable for acoustic wave problems. The objective of this project is to develop a high order unstructured grid Dispersion-Relation-Preserving (DRP) scheme. would minimize numerical dispersion and dissipation errors. contains the results of the funded portion of the project. scheme on an unstructured grid has been developed. constructed in the wave number space. The characteristics of the scheme can be improved by the inclusion of additional constraints. Stability of the scheme has been investigated. Stability can be improved by adopting the upwinding strategy.

  17. Advanced methods for displays and remote control of robots.

    PubMed

    Eliav, Ami; Lavie, Talia; Parmet, Yisrael; Stern, Helman; Edan, Yael

    2011-11-01

    An in-depth evaluation of the usability and situation awareness performance of different displays and destination controls of robots are presented. In two experiments we evaluate the way information is presented to the operator and assess different means for controlling the robot. Our study compares three types of displays: a "blocks" display, a HUD (head-up display), and a radar display, and two types of controls: touch screen and hand gestures. The HUD demonstrated better performance when compared to the blocks display and was perceived to have greater usability compared to the radar display. The HUD was also found to be more useful when the operation of the robot was more difficult, i.e., when using the hand-gesture method. The experiments also pointed to the importance of using a wide viewing angle to minimize distortion and for easier coping with the difficulties of locating objects in the field of view margins. The touch screen was found to be superior in terms of both objective performance and its perceived usability. No differences were found between the displays and the controllers in terms of situation awareness. This research sheds light on the preferred display type and controlling method for operating robots from a distance, making it easier to cope with the challenges of operating such systems.

  18. Advanced criticality assessment method for sewer pipeline assets.

    PubMed

    Syachrani, S; Jeong, H D; Chung, C S

    2013-01-01

    For effective management of water and wastewater infrastructure, the United States Environmental Protection Agency (US-EPA) has long emphasized the significant role of risk in prioritizing and optimizing asset management decisions. High risk assets are defined as assets with a high probability of failure (e.g. soon to fail, old, poor condition) and high consequences of failure (e.g. environmental impact, high expense, safety concerns, social disruption). In practice, the consequences of failure are often estimated by experts through a Delphi method. However, the estimation of the probability of failure has been challenging as it requires the thorough analysis of the historical condition assessment data, repair and replacement records, and other factors influencing the deterioration of the asset. The most common predictor in estimating the probability of failure is calendar age. However, a simple reliance on calendar age as a basis for estimating the asset's deterioration pattern completely ignores the different aging characteristics influenced by various operational and environmental conditions. This paper introduces a new approach of using 'real age' in estimating the probability of failure. Unlike the traditional calendar age method, the real age represents the adjusted age based on the unique operational and environmental conditions of the asset. Depending on the individual deterioration pattern, the real age could be higher or lower than its calendar age. Using the concept of real age, the probability of failure of an asset can be more accurately estimated.

  19. Front-flash thermal imaging characterization of continuous fiber ceramic composites.

    SciTech Connect

    Deemer, C.

    1999-04-23

    Infrared thermal imaging has become increasingly popular as a nondestructive evaluation method for characterizing materials and detecting defects. One technique, which was utilized in this study, is front-flash thermal imaging. We have developed a thermal imaging system that uses this technique to characterize advanced material systems, including continuous fiber ceramic composite (CFCC) components. In a front-flash test, pulsed heat energy is applied to the surface of a sample, and decay of the surface temperature is then measured by the thermal imaging system. CFCC samples with drilled flat-bottom holes at the back surface (to serve as ''flaws'') were examined. The surface-temperature/time relationship was analyzed to determine the depths of the flaws from the front surface of the CFCC material. Experimental results on carbon/carbon and CFCC samples are presented and discussed.

  20. Method of Suppressing Sublimation in Advanced Thermoelectric Devices

    NASA Technical Reports Server (NTRS)

    Sakamoto, Jeffrey S. (Inventor); Caillat, Thierry (Inventor); Fleurial, Jean-Pierre (Inventor); Snyder, G. Jeffrey (Inventor)

    2009-01-01

    A method of applying a physical barrier to suppress thermal decomposition near a surface of a thermoelectric material including applying a continuous metal foil to a predetermined portion of the surface of the thermoelectric material, physically binding the continuous metal foil to the surface of the thermoelectric material using a binding member, and heating in a predetermined atmosphere the applied and physically bound continuous metal foil and the thermoelectric material to a sufficient temperature in order to promote bonding between the continuous metal foil and the surface of the thermoelectric material. The continuous metal foil forms a physical barrier to enclose a predetermined portion of the surface. Thermal decomposition is suppressed at the surface of the thermoelectric material enclosed by the physical barrier when the thermoelectric element is in operation.

  1. Comparative Assessment of Advanced Gay Hydrate Production Methods

    SciTech Connect

    M. D. White; B. P. McGrail; S. K. Wurstner

    2009-06-30

    Displacing natural gas and petroleum with carbon dioxide is a proven technology for producing conventional geologic hydrocarbon reservoirs, and producing additional yields from abandoned or partially produced petroleum reservoirs. Extending this concept to natural gas hydrate production offers the potential to enhance gas hydrate recovery with concomitant permanent geologic sequestration. Numerical simulation was used to assess a suite of carbon dioxide injection techniques for producing gas hydrates from a variety of geologic deposit types. Secondary hydrate formation was found to inhibit contact of the injected CO{sub 2} regardless of injectate phase state, thus diminishing the exchange rate due to pore clogging and hydrate zone bypass of the injected fluids. Additional work is needed to develop methods of artificially introducing high-permeability pathways in gas hydrate zones if injection of CO{sub 2} in either gas, liquid, or micro-emulsion form is to be more effective in enhancing gas hydrate production rates.

  2. Advanced hydraulic fracturing methods to create in situ reactive barriers

    SciTech Connect

    Murdoch, L. |; Siegrist, B.; Vesper, S.

    1997-12-31

    Many contaminated areas consist of a source area and a plume. In the source area, the contaminant moves vertically downward from a release point through the vadose zone to an underlying saturated region. Where contaminants are organic liquids, NAPL may accumulate on the water table, or it may continue to migrate downward through the saturated region. Early developments of permeable barrier technology have focused on intercepting horizontally moving plumes with vertical structures, such as trenches, filled with reactive material capable of immobilizing or degrading dissolved contaminants. This focus resulted in part from a need to economically treat the potentially large volumes of contaminated water in a plume, and in part from the availability of construction technology to create the vertical structures that could house reactive compounds. Contaminant source areas, however, have thus far remained largely excluded from the application of permeable barrier technology. One reason for this is the lack of conventional construction methods for creating suitable horizontal structures that would place reactive materials in the path of downward-moving contaminants. Methods of hydraulic fracturing have been widely used to create flat-lying to gently dipping layers of granular material in unconsolidated sediments. Most applications thus far have involved filling fractures with coarse-grained sand to create permeable layers that will increase the discharge of wells recovering contaminated water or vapor. However, it is possible to fill fractures with other compounds that alter the chemical composition of the subsurface. One early application involved development and field testing micro-encapsulated sodium percarbonate, a solid compound that releases oxygen and can create aerobic conditions suitable for biodegradation in the subsurface for several months.

  3. Advanced view factor analysis method for radiation exchange

    NASA Astrophysics Data System (ADS)

    Park, Sookuk; Tuller, Stanton E.

    2014-03-01

    A raster-based method for determining complex view factor patterns is presented (HURES model). The model uses Johnson and Watson's view factor analysis method for fisheye lens photographs. The entire sphere is divided into 13 different view factors: open sky; sunny and shaded building walls, vegetation (trees) and ground surfaces above and below 1.2 m from the ground surface. The HURES model gave reasonable view factor results in tests at two urban study sites on summer days: downtown Nanaimo, B.C., Canada and Changwon, Republic of Korea. HURES gave better estimates of open sky view factors determined from fisheye lens photographs than did ENVI-met 3.1 and RayMan Pro. However, all three models underestimated sky view factor. For view factor analysis in outdoor urban areas, the 10° interval of rotation angle at 100 m distance of annuli will be suitable settings for three-dimensional computer simulations. The HURES model can be used for the rapid determination of complex view factor patterns which facilitates the analysis of their effects. Examples of how differing view factor patterns can affect human thermal sensation indices are given. The greater proportion of sunny view factors increased the computed predicted mean vote (PMV) by 1.3 on the sunny side of the street compared with the shady side during mid-morning in downtown Nanaimo. In another example, effects of differing amounts of open sky, sunny ground, sunny buildings and vegetation combined to produce only slight differences in PMV and two other human thermal sensation indices, PET and UTCI.

  4. An evolutionary method for synthesizing technological planning and architectural advance

    NASA Astrophysics Data System (ADS)

    Cole, Bjorn Forstrom

    In the development of systems with ever-increasing performance and/or decreasing drawbacks, there inevitably comes a point where more progress is available by shifting to a new set of principles of use. This shift marks a change in architecture, such as between the piston-driven propeller and the jet engine. The shift also often involves an abandonment of previous competencies that have been developed with great effort, and so a foreknowledge of these shifts can be advantageous. A further motivation for this work is the consideration of the Micro Autonomous Systems and Technology (MAST) project, which aims to develop very small (<5 cm) robots for a variety of uses. This is primarily a technology research project, and there is no baseline morphology for a robot to be considered. This then motivates an interest in the ability to automatically compose physical architectures from a series of components and quantitatively analyze them for a basic, conceptual analysis. The ability to do this would enable researchers to turn attention to the most promising forms. This work presents a method for using technology forecasts of components that enable future architectural shifts in order to forecast those shifts. The method consists of the use of multidimensional S-curves, genetic algorithms, and a graph-based formulation of architecture that is more flexible than other morphological techniques. Potential genetic operators are explored in depth to draft a final graph-based genetic algorithm. This algorithm is then implemented in a design code called Sindri, which leverages a commercial design tool named Pacelab. The first chapters of this thesis provide context and a philosophical background to the studies and research that was conducted. In particular, the idea that technology progresses in a fundamentally gradual way is developed and supported with previous historical research. The import of this is that the future can to some degree be predicted by the past, provided that

  5. Front Range Branch Officers

    NASA Astrophysics Data System (ADS)

    The Front Range Branch of AGU has installed officers for 1990: Ray Noble, National Center for Atmospheric Research, chair; Sherry Oaks, U.S. Geological Survey, chair-elect; Howard Garcia, NOAA, treasurer; Catharine Skokan, Colorado School of Mines, secretary. JoAnn Joselyn of NOAA is past chair. Members at large are Wallace Campbell, NOAA; William Neff, USGS; and Stephen Schneider, NCAR.

  6. Stories from the Front.

    ERIC Educational Resources Information Center

    Melnick, Blake

    2002-01-01

    Shares some of the author's personal experiences from the "front line" to illustrate the potential of computer-supported learning environments. Concludes that technology, if used in conjunction with sound pedagogy, allows students to tep outside the confines of the traditional classroom and school structure and take responsibility for both their…

  7. Foam front propagation in anisotropic oil reservoirs.

    PubMed

    Grassia, P; Torres-Ulloa, C; Berres, S; Mas-Hernández, E; Shokri, N

    2016-04-01

    The pressure-driven growth model is considered, describing the motion of a foam front through an oil reservoir during foam improved oil recovery, foam being formed as gas advances into an initially liquid-filled reservoir. In the model, the foam front is represented by a set of so-called "material points" that track the advance of gas into the liquid-filled region. According to the model, the shape of the foam front is prone to develop concave sharply curved concavities, where the orientation of the front changes rapidly over a small spatial distance: these are referred to as "concave corners". These concave corners need to be propagated differently from the material points on the foam front itself. Typically the corner must move faster than those material points, otherwise spurious numerical artifacts develop in the computed shape of the front. A propagation rule or "speed up" rule is derived for the concave corners, which is shown to be sensitive to the level of anisotropy in the permeability of the reservoir and also sensitive to the orientation of the corners themselves. In particular if a corner in an anisotropic reservoir were to be propagated according to an isotropic speed up rule, this might not be sufficient to suppress spurious numerical artifacts, at least for certain orientations of the corner. On the other hand, systems that are both heterogeneous and anisotropic tend to be well behaved numerically, regardless of whether one uses the isotropic or anisotropic speed up rule for corners. This comes about because, in the heterogeneous and anisotropic case, the orientation of the corner is such that the "correct" anisotropic speed is just very slightly less than the "incorrect" isotropic one. The anisotropic rule does however manage to keep the corner very slightly sharper than the isotropic rule does.

  8. Advanced methods for preparation and characterization of infrared detector materials

    NASA Technical Reports Server (NTRS)

    Broerman, J. G.; Morris, B. J.; Meschter, P. J.

    1983-01-01

    Crystals were prepared by the Bridgman-Stockbarger method with a wide range of crystal growth rates and temperature gradients adequate to prevent constitutional supercooling under diffusion-limited, steady-state, growth conditions. The longitudinal compositional gradients for different growth conditions and alloy compositions were calculated and compared with experimental data to develop a quantitative model of solute redistribution during the crystal growth of the alloys. Measurements were performed to ascertain the effect of growth conditions on radial compositional gradients. The pseudobinary HgTe-CdTe constitutional phase diagram was determined by precision differential-thermal-analysis measurements and used to calculate the segregation coefficient of Cd as a function of x and interface temperature. Experiments were conducted to determine the ternary phase equilibria in selected regions of the Hg-Cd-Te constitutional phase diagram. Electron and hole mobilities as functions of temperature were analyzed to establish charge-carrier scattering probabilities. Computer algorithms specific to Hg(1-x)CdxTe were developed for calculations of the charge-carrier concentration, charge-carrier mobilities, Hall coefficient, and Dermi Fermi energy as functions of x, temperature, ionized donor and acceptor concentrations, and neutral defect concentrations.

  9. Advancing Methods for U.S. Transgender Health Research

    PubMed Central

    Reisner, Sari L.; Deutsch, Madeline B.; Bhasin, Shalender; Bockting, Walter; Brown, George R.; Feldman, Jamie; Garofalo, Rob; Kreukels, Baudewijntje; Radix, Asa; Safer, Joshua D.; Tangpricha, Vin; T’Sjoen, Guy; Goodman, Michael

    2016-01-01

    Purpose of Review To describe methodological challenges, gaps, and opportunities in U.S. transgender health research. Recent Findings Lack of large prospective observational studies and intervention trials, limited data on risks and benefits of gender affirmation (e.g., hormones and surgical interventions), and inconsistent use of definitions across studies hinder evidence-based care for transgender people. Systematic high-quality observational and intervention-testing studies may be carried out using several approaches, including general population-based, health systems-based, clinic-based, venue-based, and hybrid designs. Each of these approaches has its strength and limitations; however, harmonization of research efforts is needed. Ongoing development of evidence-based clinical recommendations will benefit from a series of observational and intervention studies aimed at identification, recruitment, and follow-up of transgender people of different ages, from different racial, ethnic, and socioeconomic backgrounds and with diverse gender identities. Summary Transgender health research faces challenges that include standardization of lexicon, agreed-upon population definitions, study design, sampling, measurement, outcome ascertainment, and sample size. Application of existing and new methods is needed to fill existing gaps, increase the scientific rigor and reach of transgender health research, and inform evidence-based prevention and care for this underserved population. PMID:26845331

  10. Recent advancements in mechanical reduction methods: particulate systems.

    PubMed

    Leleux, Jardin; Williams, Robert O

    2014-03-01

    The screening of new active pharmaceutical ingredients (APIs) has become more streamlined and as a result the number of new drugs in the pipeline is steadily increasing. However, a major limiting factor of new API approval and market introduction is the low solubility associated with a large percentage of these new drugs. While many modification strategies have been studied to improve solubility such as salt formation and addition of cosolvents, most provide only marginal success and have severe disadvantages. One of the most successful methods to date is the mechanical reduction of drug particle size, inherently increasing the surface area of the particles and, as described by the Noyes-Whitney equation, the dissolution rate. Drug micronization has been the gold standard to achieve these improvements; however, the extremely low solubility of some new chemical entities is not significantly affected by size reduction in this range. A reduction in size to the nanometric scale is necessary. Bottom-up and top-down techniques are utilized to produce drug crystals in this size range; however, as discussed in this review, top-down approaches have provided greater enhancements in drug usability on the industrial scale. The six FDA approved products that all exploit top-down approaches confirm this. In this review, the advantages and disadvantages of both approaches will be discussed in addition to specific top-down techniques and the improvements they contribute to the pharmaceutical field.

  11. Recent advances for the production and recovery methods of lysozyme.

    PubMed

    Ercan, Duygu; Demirci, Ali

    2016-12-01

    Lysozyme is an antimicrobial peptide with a high enzymatic activity and positive charges. Therefore, it has applications in food and pharmaceutical industries as an antimicrobial agent. Lysozyme is ubiquitous in both animal and plant kingdoms. Currently, egg-white lysozyme is the most commercially available form of lysozyme. The main concerns of egg-white lysozyme are high recovery cost, low activity and most importantly the immunological problems to some people. Therefore, human lysozyme production has gained importance in recent years. Scientists have developed transgenic plants, animals and microorganisms that can produce human lysozyme. Out of these, microbial production has advantages for commercial productions, because high production levels are achievable in a relatively short time. It has been reported that fermentation parameters, such as pH, temperature, aeration, are key factors to increase the effectiveness of the human lysozyme production. Moreover, purification of the lysozyme from the fermentation broth needs to be optimized for the economical production. In conclusion, this review paper covers the mechanism of lysozyme, its sources, production methods and recovery of lysozyme.

  12. Investigation of advanced fault insertion and simulator methods

    NASA Technical Reports Server (NTRS)

    Dunn, W. R.; Cottrell, D.

    1986-01-01

    The cooperative agreement partly supported research leading to the open-literature publication cited. Additional efforts under the agreement included research into fault modeling of semiconductor devices. Results of this research are presented in this report which is summarized in the following paragraphs. As a result of the cited research, it appears that semiconductor failure mechanism data is abundant but of little use in developing pin-level device models. Failure mode data on the other hand does exist but is too sparse to be of any statistical use in developing fault models. What is significant in the failure mode data is that, unlike classical logic, MSI and LSI devices do exhibit more than 'stuck-at' and open/short failure modes. Specifically they are dominated by parametric failures and functional anomalies that can include intermittent faults and multiple-pin failures. The report discusses methods of developing composite pin-level models based on extrapolation of semiconductor device failure mechanisms, failure modes, results of temperature stress testing and functional modeling. Limitations of this model particularly with regard to determination of fault detection coverage and latency time measurement are discussed. Indicated research directions are presented.

  13. Advanced Density Functional Theory Methods for Materials Science

    NASA Astrophysics Data System (ADS)

    Demers, Steven

    In this work we chiefly deal with two broad classes of problems in computational materials science, determining the doping mechanism in a semiconductor and developing an extreme condition equation of state. While solving certain aspects of these questions is well-trodden ground, both require extending the reach of existing methods to fully answer them. Here we choose to build upon the framework of density functional theory (DFT) which provides an efficient means to investigate a system from a quantum mechanics description. Zinc Phosphide (Zn3P2) could be the basis for cheap and highly efficient solar cells. Its use in this regard is limited by the difficulty in n-type doping the material. In an effort to understand the mechanism behind this, the energetics and electronic structure of intrinsic point defects in zinc phosphide are studied using generalized Kohn-Sham theory and utilizing the Heyd, Scuseria, and Ernzerhof (HSE) hybrid functional for exchange and correlation. Novel 'perturbation extrapolation' is utilized to extend the use of the computationally expensive HSE functional to this large-scale defect system. According to calculations, the formation energy of charged phosphorus interstitial defects are very low in n-type Zn3P2 and act as 'electron sinks', nullifying the desired doping and lowering the fermi-level back towards the p-type regime. Going forward, this insight provides clues to fabricating useful zinc phosphide based devices. In addition, the methodology developed for this work can be applied to further doping studies in other systems. Accurate determination of high pressure and temperature equations of state is fundamental in a variety of fields. However, it is often very difficult to cover a wide range of temperatures and pressures in an laboratory setting. Here we develop methods to determine a multi-phase equation of state for Ta through computation. The typical means of investigating thermodynamic properties is via 'classical' molecular

  14. Advanced Extraction Methods for Actinide/Lanthanide Separations

    SciTech Connect

    Scott, M.J.

    2005-12-01

    The separation of An(III) ions from chemically similar Ln(III) ions is perhaps one of the most difficult problems encountered during the processing of nuclear waste. In the 3+ oxidation states, the metal ions have an identical charge and roughly the same ionic radius. They differ strictly in the relative energies of their f- and d-orbitals, and to separate these metal ions, ligands will need to be developed that take advantage of this small but important distinction. The extraction of uranium and plutonium from nitric acid solution can be performed quantitatively by the extraction with the TBP (tributyl phosphate). Commercially, this process has found wide use in the PUREX (plutonium uranium extraction) reprocessing method. The TRUEX (transuranium extraction) process is further used to coextract the trivalent lanthanides and actinides ions from HLLW generated during PUREX extraction. This method uses CMPO [(N, N-diisobutylcarbamoylmethyl) octylphenylphosphineoxide] intermixed with TBP as a synergistic agent. However, the final separation of trivalent actinides from trivalent lanthanides still remains a challenging task. In TRUEX nitric acid solution, the Am(III) ion is coordinated by three CMPO molecules and three nitrate anions. Taking inspiration from this data and previous work with calix[4]arene systems, researchers on this project have developed a C3-symmetric tris-CMPO ligand system using a triphenoxymethane platform as a base. The triphenoxymethane ligand systems have many advantages for the preparation of complex ligand systems. The compounds are very easy to prepare. The steric and solubility properties can be tuned through an extreme range by the inclusion of different alkoxy and alkyl groups such as methyoxy, ethoxy, t-butoxy, methyl, octyl, t-pentyl, or even t-pentyl at the ortho- and para-positions of the aryl rings. The triphenoxymethane ligand system shows promise as an improved extractant for both tetravalent and trivalent actinide recoveries form

  15. Perturbative High Harmonic Wave Front Control

    NASA Astrophysics Data System (ADS)

    Li, Zhengyan; Brown, Graham; Ko, Dong Hyuk; Kong, Fanqi; Arissian, Ladan; Corkum, P. B.

    2017-01-01

    We pattern the wave front of a high harmonic beam by intersecting the intense driving laser pulse that generates the high harmonic with a weak control pulse. To illustrate the potential of wave-front control, we imprint a Fresnel zone plate pattern on a harmonic beam, causing the harmonics to focus and defocus. The quality of the focus that we achieve is measured using the spectral wave-front optical reconstruction by diffraction method. We will show that it is possible to enhance the peak intensity by orders of magnitude without a physical optical element in the path of the extreme ultraviolet (XUV) beam. Through perturbative wave-front control, XUV beams can be created with a flexibility approaching what technology allows for visible and infrared light.

  16. 3. VIEW NORTH, SOUTHWEST FRONT, SOUTHEAST SIDE Front and side ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW NORTH, SOUTHWEST FRONT, SOUTHEAST SIDE Front and side elevation. Note gasoline sign post added. Flush store window not altered, 1900 clapboard siding and panelling remaining. - 510 Central Avenue (Commercial Building), Ridgely, Caroline County, MD

  17. 9. DETAIL OF INTERIOR OF FRONT PORCH SHOWING FRONT ENTRY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. DETAIL OF INTERIOR OF FRONT PORCH SHOWING FRONT ENTRY (LEFT) AND BLANK WALL (CENTER) CORRESPONDING TO LOCATION OF INTERIOR VAULTS. VIEW TO SOUTHEAST. - Boise Project, Boise Project Office, 214 Broadway, Boise, Ada County, ID

  18. 35. EAST FRONT OF POWERHOUSE AND CAR BARN: East front ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. EAST FRONT OF POWERHOUSE AND CAR BARN: East front of powerhouse and car barn. 'Annex' is right end of building. - San Francisco Cable Railway, Washington & Mason Streets, San Francisco, San Francisco County, CA

  19. Advancing the study of violence against women using mixed methods: integrating qualitative methods into a quantitative research program.

    PubMed

    Testa, Maria; Livingston, Jennifer A; VanZile-Tamsen, Carol

    2011-02-01

    A mixed methods approach, combining quantitative with qualitative data methods and analysis, offers a promising means of advancing the study of violence. Integrating semi-structured interviews and qualitative analysis into a quantitative program of research on women's sexual victimization has resulted in valuable scientific insight and generation of novel hypotheses for testing. This mixed methods approach is described and recommendations for integrating qualitative data into quantitative research are provided.

  20. ADVANCING THE STUDY OF VIOLENCE AGAINST WOMEN USING MIXED METHODS: INTEGRATING QUALITATIVE METHODS INTO A QUANTITATIVE RESEARCH PROGRAM

    PubMed Central

    Testa, Maria; Livingston, Jennifer A.; VanZile-Tamsen, Carol

    2011-01-01

    A mixed methods approach, combining quantitative with qualitative data methods and analysis, offers a promising means of advancing the study of violence. Integrating semi-structured interviews and qualitative analysis into a quantitative program of research on women’s sexual victimization has resulted in valuable scientific insight and generation of novel hypotheses for testing. This mixed methods approach is described and recommendations for integrating qualitative data into quantitative research are provided. PMID:21307032

  1. Method and system for advancement of a borehole using a high power laser

    DOEpatents

    Moxley, Joel F.; Land, Mark S.; Rinzler, Charles C.; Faircloth, Brian O.; Zediker, Mark S.

    2014-09-09

    There is provided a system, apparatus and methods for the laser drilling of a borehole in the earth. There is further provided with in the systems a means for delivering high power laser energy down a deep borehole, while maintaining the high power to advance such boreholes deep into the earth and at highly efficient advancement rates, a laser bottom hole assembly, and fluid directing techniques and assemblies for removing the displaced material from the borehole.

  2. Advancing Reactive Tracer Methods for Measurement of Thermal Evolution in Geothermal Reservoirs: Final Report

    SciTech Connect

    Mitchell A. Plummer; Carl D. Palmer; Earl D. Mattson; Laurence C. Hull; George D. Redden

    2011-07-01

    The injection of cold fluids into engineered geothermal system (EGS) and conventional geothermal reservoirs may be done to help extract heat from the subsurface or to maintain pressures within the reservoir (e.g., Rose et al., 2001). As these injected fluids move along fractures, they acquire heat from the rock matrix and remove it from the reservoir as they are extracted to the surface. A consequence of such injection is the migration of a cold-fluid front through the reservoir (Figure 1) that could eventually reach the production well and result in the lowering of the temperature of the produced fluids (thermal breakthrough). Efficient operation of an EGS as well as conventional geothermal systems involving cold-fluid injection requires accurate and timely information about thermal depletion of the reservoir in response to operation. In particular, accurate predictions of the time to thermal breakthrough and subsequent rate of thermal drawdown are necessary for reservoir management, design of fracture stimulation and well drilling programs, and forecasting of economic return. A potential method for estimating migration of a cold front between an injection well and a production well is through application of reactive tracer tests, using chemical whose rate of degradation is dependent on the reservoir temperature between the two wells (e.g., Robinson 1985). With repeated tests, the rate of migration of the thermal front can be determined, and the time to thermal breakthrough calculated. While the basic theory behind the concept of thermal tracers has been understood for some time, effective application of the method has yet to be demonstrated. This report describes results of a study that used several methods to investigate application of reactive tracers to monitoring the thermal evolution of a geothermal reservoir. These methods included (1) mathematical investigation of the sensitivity of known and hypothetical reactive tracers, (2) laboratory testing of novel

  3. Recent advances in computational methods for nuclear magnetic resonance data processing.

    PubMed

    Gao, Xin

    2013-02-01

    Although three-dimensional protein structure determination using nuclear magnetic resonance (NMR) spectroscopy is a computationally costly and tedious process that would benefit from advanced computational techniques, it has not garnered much research attention from specialists in bioinformatics and computational biology. In this paper, we review recent advances in computational methods for NMR protein structure determination. We summarize the advantages of and bottlenecks in the existing methods and outline some open problems in the field. We also discuss current trends in NMR technology development and suggest directions for research on future computational methods for NMR.

  4. Theory of pinned fronts

    NASA Astrophysics Data System (ADS)

    Weissmann, Haim; Shnerb, Nadav M.; Kessler, David A.

    2016-01-01

    The properties of a front between two different phases in the presence of a smoothly inhomogeneous external field that takes its critical value at the crossing point is analyzed. Two generic scenarios are studied. In the first, the system admits a bistable solution and the external field governs the rate in which one phase invades the other. The second mechanism corresponds to a continuous transition that, in the case of reactive systems, takes the form of a transcritical bifurcation at the crossing point. We solve for the front shape and for the response of competitive fronts to external noise, showing that static properties and also some of the dynamical features cannot discriminate between the two scenarios. A reliable indicator turns out to be the fluctuation statistics. These take a Gaussian form in the bifurcation case and a double-peaked shape in a bistable system. Our results are discussed in the context of biological processes, such as species and communities dynamics in the presence of a resource gradient.

  5. Radiative thermal conduction fronts

    NASA Astrophysics Data System (ADS)

    Borkowski, Kazimierz J.; Balbus, Steven A.; Fristrom, Carl C.

    1990-07-01

    The discovery of the O VI interstellar absorption lines in our Galaxy by the Copernicus observatory was a turning point in our understanding of the Interstellar Medium (ISM). It implied the presence of widespread hot (approx. 10 to the 6th power K) gas in disk galaxies. The detection of highly ionized species in quasi-stellar objects' absorption spectra may be the first indirect observation of this hot phase in external disk galaxies. Previous efforts to understand extensive O VI absorption line data from our Galaxy were not very successful in locating the regions where this absorption originates. The location at interfaces between evaporating ISM clouds and hot gas was favored, but recent studies of steady-state conduction fronts in spherical clouds by Ballet, Arnaud, and Rothenflug (1986) and Bohringer and Hartquist (1987) rejected evaporative fronts as the absorption sites. Researchers report here on time-dependent nonequilibrium calculations of planar conductive fronts whose properties match well with observations, and suggest reasons for the difference between the researchers' results and the above. They included magnetic fields in additional models, not reported here, and the conclusions are not affected by their presence.

  6. Front Range Report, Abstracts

    NASA Astrophysics Data System (ADS)

    Spence, William

    The second regional conference of the Front Range Branch, AGU, was attended by more than 80 professionals and some 20 outstanding high school students. The conference included 2 days of interdisciplinary talks, and lots of discussion, that primarily were keyed to geophysical studies of Colorado, Wyoming, and New Mexico. Other talks reported on nonregional, and sometimes global, studies being done by geophypsicists of the Front Range region.Topics included tectonics of the Front Range and the Colorado Plateau, pollution of the Arkansas and Mississippi rivers, and a supreme polluting event that caused the late-Cretaceous extinctions. Other notable talks were on toxic cleanup, microburst (wind shear) detection at U.S. airports, and other meteorological studies. Several talks treated the audience to the excitement of new work and surprise discoveries. The meeting was multimedia, including the playing of two videos through a projection TV and the playing of a fascinating tape between an airport control tower and incoming pilots during a severe microburst event.

  7. Radiative thermal conduction fronts

    NASA Technical Reports Server (NTRS)

    Borkowski, Kazimierz J.; Balbus, Steven A.; Fristrom, Carl C.

    1990-01-01

    The discovery of the O VI interstellar absorption lines in our Galaxy by the Copernicus observatory was a turning point in our understanding of the Interstellar Medium (ISM). It implied the presence of widespread hot (approx. 10 to the 6th power K) gas in disk galaxies. The detection of highly ionized species in quasi-stellar objects' absorption spectra may be the first indirect observation of this hot phase in external disk galaxies. Previous efforts to understand extensive O VI absorption line data from our Galaxy were not very successful in locating the regions where this absorption originates. The location at interfaces between evaporating ISM clouds and hot gas was favored, but recent studies of steady-state conduction fronts in spherical clouds by Ballet, Arnaud, and Rothenflug (1986) and Bohringer and Hartquist (1987) rejected evaporative fronts as the absorption sites. Researchers report here on time-dependent nonequilibrium calculations of planar conductive fronts whose properties match well with observations, and suggest reasons for the difference between the researchers' results and the above. They included magnetic fields in additional models, not reported here, and the conclusions are not affected by their presence.

  8. Light-Front Quantization of Gauge Theories

    SciTech Connect

    Brodskey, Stanley

    2002-12-01

    Light-front wavefunctions provide a frame-independent representation of hadrons in terms of their physical quark and gluon degrees of freedom. The light-front Hamiltonian formalism provides new nonperturbative methods for obtaining the QCD spectrum and eigensolutions, including resolvant methods, variational techniques, and discretized light-front quantization. A new method for quantizing gauge theories in light-cone gauge using Dirac brackets to implement constraints is presented. In the case of the electroweak theory, this method of light-front quantization leads to a unitary and renormalizable theory of massive gauge particles, automatically incorporating the Lorentz and 't Hooft conditions as well as the Goldstone boson equivalence theorem. Spontaneous symmetry breaking is represented by the appearance of zero modes of the Higgs field leaving the light-front vacuum equal to the perturbative vacuum. I also discuss an ''event amplitude generator'' for automatically computing renormalized amplitudes in perturbation theory. The importance of final-state interactions for the interpretation of diffraction, shadowing, and single-spin asymmetries in inclusive reactions such as deep inelastic lepton-hadron scattering is emphasized.

  9. Test Method Designed to Evaluate Cylinder Liner-Piston Ring Coatings for Advanced Heat Engines

    NASA Technical Reports Server (NTRS)

    Radil, Kevin C.

    1997-01-01

    Research on advanced heat engine concepts, such as the low-heat-rejection engine, have shown the potential for increased thermal efficiency, reduced emissions, lighter weight, simpler design, and longer life in comparison to current diesel engine designs. A major obstacle in the development of a functional advanced heat engine is overcoming the problems caused by the high combustion temperatures at the piston ring/cylinder liner interface, specifically at top ring reversal (TRR). Therefore, advanced cylinder liner and piston ring materials are needed that can survive under these extreme conditions. To address this need, researchers at the NASA Lewis Research Center have designed a tribological test method to help evaluate candidate piston ring and cylinder liner materials for advanced diesel engines.

  10. FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance

    NASA Technical Reports Server (NTRS)

    Harris, Charles E. (Editor)

    1994-01-01

    International technical experts in durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The symposium focused on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure, criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and advanced approaches to resist corrosion and environmentally assisted fatigue.

  11. THERMAL FRONTS IN SOLAR FLARES

    SciTech Connect

    Karlický, Marian

    2015-12-01

    We studied the formation of a thermal front during the expansion of hot plasma into colder plasma. We used a three-dimensional electromagnetic particle-in-cell model that includes inductive effects. In early phases, in the area of the expanding hot plasma, we found several thermal fronts, which are defined as a sudden decrease of the local electron kinetic energy. The fronts formed a cascade. Thermal fronts with higher temperature contrast were located near plasma density depressions, generated during the hot plasma expansion. The formation of the main thermal front was associated with the return-current process induced by hot electron expansion and electrons backscattered at the front. A part of the hot plasma was trapped by the thermal front while another part, mainly with the most energetic electrons, escaped and generated Langmuir and electromagnetic waves in front of the thermal front, as shown by the dispersion diagrams. Considering all of these processes and those described in the literature, we show that anomalous electric resistivity is produced at the location of the thermal front. Thus, the thermal front can contribute to energy dissipation in the current-carrying loops of solar flares. We estimated the values of such anomalous resistivity in the solar atmosphere together with collisional resistivity and electric fields. We propose that the slowly drifting reverse drift bursts, observed at the beginning of some solar flares, could be signatures of the thermal front.

  12. Human-System Safety Methods for Development of Advanced Air Traffic Management Systems

    SciTech Connect

    Nelson, W.R.

    1999-05-24

    The Idaho National Engineering and Environmental Laboratory (INEEL) is supporting the National Aeronautics and Space Administration in the development of advanced air traffic management (ATM) systems as part of the Advanced Air Transportation Technologies program. As part of this program INEEL conducted a survey of human-system safety methods that have been applied to complex technical systems, to identify lessons learned from these applications and provide recommendations for the development of advanced ATM systems. The domains that were surveyed included offshore oil and gas, commercial nuclear power, commercial aviation, and military. The survey showed that widely different approaches are used in these industries, and that the methods used range from very high-level, qualitative approaches to very detailed quantitative methods such as human reliability analysis (HRA) and probabilistic safety assessment (PSA). In addition, the industries varied widely in how effectively they incorporate human-system safety assessment in the design, development, and testing of complex technical systems. In spite of the lack of uniformity in the approaches and methods used, it was found that methods are available that can be combined and adapted to support the development of advanced air traffic management systems.

  13. QCD and Light-Front Dynamics

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.; /SLAC /Southern Denmark U., CP3-Origins /Costa Rica U.

    2011-01-10

    AdS/QCD, the correspondence between theories in a dilaton-modified five-dimensional anti-de Sitter space and confining field theories in physical space-time, provides a remarkable semiclassical model for hadron physics. Light-front holography allows hadronic amplitudes in the AdS fifth dimension to be mapped to frame-independent light-front wavefunctions of hadrons in physical space-time. The result is a single-variable light-front Schroedinger equation which determines the eigenspectrum and the light-front wavefunctions of hadrons for general spin and orbital angular momentum. The coordinate z in AdS space is uniquely identified with a Lorentz-invariant coordinate {zeta} which measures the separation of the constituents within a hadron at equal light-front time and determines the off-shell dynamics of the bound state wavefunctions as a function of the invariant mass of the constituents. The hadron eigenstates generally have components with different orbital angular momentum; e.g., the proton eigenstate in AdS/QCD with massless quarks has L = 0 and L = 1 light-front Fock components with equal probability. Higher Fock states with extra quark-anti quark pairs also arise. The soft-wall model also predicts the form of the nonperturbative effective coupling and its {beta}-function. The AdS/QCD model can be systematically improved by using its complete orthonormal solutions to diagonalize the full QCD light-front Hamiltonian or by applying the Lippmann-Schwinger method to systematically include QCD interaction terms. Some novel features of QCD are discussed, including the consequences of confinement for quark and gluon condensates. A method for computing the hadronization of quark and gluon jets at the amplitude level is outlined.

  14. Advanced Manufacturing Methods for Systems of Microsystem Nanospacecraft- Status of the Project

    NASA Astrophysics Data System (ADS)

    Plesseria, J. Y.; Corbelli, A.; Masse, C.; Rigo, O.; Pambaguian, L.; Bonvoisin, B.

    2014-06-01

    In the frame of an ESA TRP project, CSL, SIRRIS, ALMASpace and TAS-F associated to evaluate advanced manufacturing methods for application to space hardware.The state of the art of the new manufacturing methods, including additive manufacturing but also advanced bonding, joining and shaping techniques has been reviewed. Then three types of case studies have been developed successively. The first type was a re- manufacture of an existing piece of hardware using advanced techniques to evaluate if there is some potential improvement to be achieved (cost, production time, complexity reduction). The second level was to design and manufacture a part based on the application requirements. The last level was to design and manufacture a part taking into account the subsystem to which it belongs. All case studies have been tested in terms of achieved performances and resistance to the mechanical and thermal environment.

  15. Some advanced parametric methods for assessing waveform distortion in a smart grid with renewable generation

    NASA Astrophysics Data System (ADS)

    Alfieri, Luisa

    2015-12-01

    Power quality (PQ) disturbances are becoming an important issue in smart grids (SGs) due to the significant economic consequences that they can generate on sensible loads. However, SGs include several distributed energy resources (DERs) that can be interconnected to the grid with static converters, which lead to a reduction of the PQ levels. Among DERs, wind turbines and photovoltaic systems are expected to be used extensively due to the forecasted reduction in investment costs and other economic incentives. These systems can introduce significant time-varying voltage and current waveform distortions that require advanced spectral analysis methods to be used. This paper provides an application of advanced parametric methods for assessing waveform distortions in SGs with dispersed generation. In particular, the Standard International Electrotechnical Committee (IEC) method, some parametric methods (such as Prony and Estimation of Signal Parameters by Rotational Invariance Technique (ESPRIT)), and some hybrid methods are critically compared on the basis of their accuracy and the computational effort required.

  16. Development of Advanced Methods of Structural and Trajectory Analysis for Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Ardema, Mark D.

    1996-01-01

    In this report the author describes: (1) development of advanced methods of structural weight estimation, and (2) development of advanced methods of flight path optimization. A method of estimating the load-bearing fuselage weight and wing weight of transport aircraft based on fundamental structural principles has been developed. This method of weight estimation represents a compromise between the rapid assessment of component weight using empirical methods based on actual weights of existing aircraft and detailed, but time-consuming, analysis using the finite element method. The method was applied to eight existing subsonic transports for validation and correlation. Integration of the resulting computer program, PDCYL, has been made into the weights-calculating module of the AirCraft SYNThesis (ACSYNT) computer program. ACSYNT bas traditionally used only empirical weight estimation methods; PDCYL adds to ACSYNT a rapid, accurate means of assessing the fuselage and wing weights of unconventional aircraft. PDCYL also allows flexibility in the choice of structural concept, as well as a direct means of determining the impact of advanced materials on structural weight.

  17. An advanced panel method for analysis of arbitrary configurations in unsteady subsonic flow

    NASA Technical Reports Server (NTRS)

    Dusto, A. R.; Epton, M. A.

    1980-01-01

    An advanced method is presented for solving the linear integral equations for subsonic unsteady flow in three dimensions. The method is applicable to flows about arbitrary, nonplanar boundary surfaces undergoing small amplitude harmonic oscillations about their steady mean locations. The problem is formulated with a wake model wherein unsteady vorticity can be convected by the steady mean component of flow. The geometric location of the unsteady source and doublet distributions can be located on the actual surfaces of thick bodies in their steady mean locations. The method is an outgrowth of a recently developed steady flow panel method and employs the linear source and quadratic doublet splines of that method.

  18. DSD front models : nonideal explosive detonation

    SciTech Connect

    Bdzil, J. B.; Short, M.; Aslam, T. D.; Catanach, R. A.; Hill, L. G.

    2001-01-01

    The Detonation Shock Dynamics (DSD) method for propagating detonation in numerical simulation of detonation in high explosive (HE) is based on three elements: (1) a subscale theory of multi-dimensional detonation that treats the evolving detonation as a front with dynamics that depends only on metrics of the front (such as curvature, etc.), (2) high-resolution direct numerical sirnuliltion of detonation serving both to test existing subscale theories and suggest modifications, and (3) physical experiments to characterize multi-dimensional detonation propagation on real explosives and to calibrate the front models for use in engineering simulations. In this paper we describe our work on all three of these elements of the DSD method as it applies to detonation in nonideal explosives.

  19. A Mixed Methods Approach to Examining an Advanced Placement Program in One Connecticut Public School District

    ERIC Educational Resources Information Center

    Docimo, Chelsey L.

    2013-01-01

    The purpose of this eleventh grade Advanced Placement (AP) program study was to determine factors associated with AP placement and subsequent student performance. This research was considered to be a mixed methods case study with elements of arrested action research. One hundred and twenty-four students, four guidance counselors, three AP…

  20. Desertification by front propagation?

    PubMed

    Zelnik, Yuval R; Uecker, Hannes; Feudel, Ulrike; Meron, Ehud

    2017-04-07

    Understanding how desertification takes place in different ecosystems is an important step in attempting to forecast and prevent such transitions. Dryland ecosystems often exhibit patchy vegetation, which has been shown to be an important factor on the possible regime shifts that occur in arid regions in several model studies. In particular, both gradual shifts that occur by front propagation, and abrupt shifts where patches of vegetation vanish at once, are a possibility in dryland ecosystems due to their emergent spatial heterogeneity. However, recent theoretical work has suggested that the final step of desertification - the transition from spotted vegetation to bare soil - occurs only as an abrupt shift, but the generality of this result, and its underlying origin, remain unclear. We investigate two models that detail the dynamics of dryland vegetation using a markedly different functional structure, and find that in both models the final step of desertification can only be abrupt. Using a careful numerical analysis, we show that this behavior is associated with the disappearance of confined spot-pattern domains as stationary states, and identify the mathematical origin of this behavior. Our findings show that a gradual desertification to bare soil due to a front propagation process can not occur in these and similar models, and opens the question of whether these dynamics can take place in nature.

  1. New Front End Technology

    SciTech Connect

    Pennington, D; Jovanovic, I; Comaskey, B J

    2001-02-01

    The next generation of Petawatt class lasers will require the development of new laser technology. Optical parametric chirped pulse amplification (OPCPA) holds a potential to increase the peak power level to >10 PW with existing grating technology through ultrashort pulses. Furthermore, by utilizing a new type of front-end system based on optical parametric amplification, pulses can be produced with substantially higher contrast than with Ti:sapphire regenerative amplifier technology. We performed extensive study of OPCPA using a single crystal-based OPA. We developed a replacement for Ti:sapphire regenerative amplifier for high peak power lasers based on OPCPA, with an output of 30 mJ, at 10 Hz repetition rate and 16.5 nm spectral bandwidth. We developed a 3D numerical model for OPCPA and we performed a theoretical study of influences of pump laser beam quality on optical parametric amplification. Our results indicate that OPCPA represents a valid replacement for Ti:sapphire in the front end of high energy short pulse lasers.

  2. Advances in explosives analysis—part I. animal, chemical, ion, and mechanical methods

    SciTech Connect

    Brown, Kathryn E.; Greenfield, Margo T.; McGrane, Shawn D.; Moore, David S.

    2015-10-13

    The number and capability of explosives detection and analysis methods have increased substantially since the publication of the Analytical and Bioanalytical Chemistry special issue devoted to Explosives Analysis (Moore and Goodpaster, Anal Bioanal Chem 395(2):245–246, 2009). We review and critically evaluate the latest (the past five years) important advances in explosives detection, with details of the improvements over previous methods, and suggest possible avenues towards further advances in, e.g., stand-off distance, detection limit, selectivity, and penetration through camouflage or packaging. The review consists of two parts. Moreover, Part I, reviews methods based on animals, chemicals (including colorimetry, molecularly imprinted polymers, electrochemistry, and immunochemistry), ions (both ion-mobility spectrometry and mass spectrometry), and mechanical devices. Part II will review methods based on photons, from very energetic photons including X-rays and gamma rays down to the terahertz range, and neutrons.

  3. Launch Vehicle Design and Optimization Methods and Priority for the Advanced Engineering Environment

    NASA Technical Reports Server (NTRS)

    Rowell, Lawrence F.; Korte, John J.

    2003-01-01

    NASA's Advanced Engineering Environment (AEE) is a research and development program that will improve collaboration among design engineers for launch vehicle conceptual design and provide the infrastructure (methods and framework) necessary to enable that environment. In this paper, three major technical challenges facing the AEE program are identified, and three specific design problems are selected to demonstrate how advanced methods can improve current design activities. References are made to studies that demonstrate these design problems and methods, and these studies will provide the detailed information and check cases to support incorporation of these methods into the AEE. This paper provides background and terminology for discussing the launch vehicle conceptual design problem so that the diverse AEE user community can participate in prioritizing the AEE development effort.

  4. Advances in explosives analysis—part II: photon and neutron methods

    DOE PAGES

    Brown, Kathryn E.; Greenfield, Margo T.; McGrane, Shawn D.; ...

    2015-10-07

    The number and capability of explosives detection and analysis methods have increased dramatically since publication of the Analytical and Bioanalytical Chemistry special issue devoted to Explosives Analysis [Moore DS, Goodpaster JV, Anal Bioanal Chem 395:245–246, 2009]. Here we review and critically evaluate the latest (the past five years) important advances in explosives detection, with details of the improvements over previous methods, and suggest possible avenues towards further advances in, e.g., stand-off distance, detection limit, selectivity, and penetration through camouflage or packaging. Our review consists of two parts. Part I discussed methods based on animals, chemicals (including colorimetry, molecularly imprinted polymers,more » electrochemistry, and immunochemistry), ions (both ion-mobility spectrometry and mass spectrometry), and mechanical devices. In Part II, we review methods based on photons, from very energetic photons including X-rays and gamma rays down to the terahertz range, and neutrons.« less

  5. Advances in explosives analysis—part I. animal, chemical, ion, and mechanical methods

    DOE PAGES

    Brown, Kathryn E.; Greenfield, Margo T.; McGrane, Shawn D.; ...

    2015-10-13

    The number and capability of explosives detection and analysis methods have increased substantially since the publication of the Analytical and Bioanalytical Chemistry special issue devoted to Explosives Analysis (Moore and Goodpaster, Anal Bioanal Chem 395(2):245–246, 2009). We review and critically evaluate the latest (the past five years) important advances in explosives detection, with details of the improvements over previous methods, and suggest possible avenues towards further advances in, e.g., stand-off distance, detection limit, selectivity, and penetration through camouflage or packaging. The review consists of two parts. Moreover, Part I, reviews methods based on animals, chemicals (including colorimetry, molecularly imprinted polymers,more » electrochemistry, and immunochemistry), ions (both ion-mobility spectrometry and mass spectrometry), and mechanical devices. Part II will review methods based on photons, from very energetic photons including X-rays and gamma rays down to the terahertz range, and neutrons.« less

  6. Advances in explosives analysis—part II: photon and neutron methods

    SciTech Connect

    Brown, Kathryn E.; Greenfield, Margo T.; McGrane, Shawn D.; Moore, David S.

    2015-10-07

    The number and capability of explosives detection and analysis methods have increased dramatically since publication of the Analytical and Bioanalytical Chemistry special issue devoted to Explosives Analysis [Moore DS, Goodpaster JV, Anal Bioanal Chem 395:245–246, 2009]. Here we review and critically evaluate the latest (the past five years) important advances in explosives detection, with details of the improvements over previous methods, and suggest possible avenues towards further advances in, e.g., stand-off distance, detection limit, selectivity, and penetration through camouflage or packaging. Our review consists of two parts. Part I discussed methods based on animals, chemicals (including colorimetry, molecularly imprinted polymers, electrochemistry, and immunochemistry), ions (both ion-mobility spectrometry and mass spectrometry), and mechanical devices. In Part II, we review methods based on photons, from very energetic photons including X-rays and gamma rays down to the terahertz range, and neutrons.

  7. Advances in methods and algorithms in a modern quantum chemistry program package.

    PubMed

    Shao, Yihan; Molnar, Laszlo Fusti; Jung, Yousung; Kussmann, Jörg; Ochsenfeld, Christian; Brown, Shawn T; Gilbert, Andrew T B; Slipchenko, Lyudmila V; Levchenko, Sergey V; O'Neill, Darragh P; DiStasio, Robert A; Lochan, Rohini C; Wang, Tao; Beran, Gregory J O; Besley, Nicholas A; Herbert, John M; Lin, Ching Yeh; Van Voorhis, Troy; Chien, Siu Hung; Sodt, Alex; Steele, Ryan P; Rassolov, Vitaly A; Maslen, Paul E; Korambath, Prakashan P; Adamson, Ross D; Austin, Brian; Baker, Jon; Byrd, Edward F C; Dachsel, Holger; Doerksen, Robert J; Dreuw, Andreas; Dunietz, Barry D; Dutoi, Anthony D; Furlani, Thomas R; Gwaltney, Steven R; Heyden, Andreas; Hirata, So; Hsu, Chao-Ping; Kedziora, Gary; Khalliulin, Rustam Z; Klunzinger, Phil; Lee, Aaron M; Lee, Michael S; Liang, Wanzhen; Lotan, Itay; Nair, Nikhil; Peters, Baron; Proynov, Emil I; Pieniazek, Piotr A; Rhee, Young Min; Ritchie, Jim; Rosta, Edina; Sherrill, C David; Simmonett, Andrew C; Subotnik, Joseph E; Woodcock, H Lee; Zhang, Weimin; Bell, Alexis T; Chakraborty, Arup K; Chipman, Daniel M; Keil, Frerich J; Warshel, Arieh; Hehre, Warren J; Schaefer, Henry F; Kong, Jing; Krylov, Anna I; Gill, Peter M W; Head-Gordon, Martin

    2006-07-21

    Advances in theory and algorithms for electronic structure calculations must be incorporated into program packages to enable them to become routinely used by the broader chemical community. This work reviews advances made over the past five years or so that constitute the major improvements contained in a new release of the Q-Chem quantum chemistry package, together with illustrative timings and applications. Specific developments discussed include fast methods for density functional theory calculations, linear scaling evaluation of energies, NMR chemical shifts and electric properties, fast auxiliary basis function methods for correlated energies and gradients, equation-of-motion coupled cluster methods for ground and excited states, geminal wavefunctions, embedding methods and techniques for exploring potential energy surfaces.

  8. From the front

    SciTech Connect

    Price, Stephen

    2009-01-01

    The causes of recent dynamic thinning of Greenland's outlet glaciers have been debated. Realistic simulations suggest that changes at the marine fronts of these glaciers are to blame, implying that dynamic thinning will cease once the glaciers retreat to higher ground. For the last decade, many outlet glaciers in Greenland that terminate in the ocean have accelerated, thinned, and retreated. To explain these dynamic changes, two hypotheses have been discussed. Atmospheric warming has increased surface melting and may also have increased the amount of meltwater reaching the glacier bed, increasing lubrication at the base and hence the rate of glacier sliding. Alternatively, a change in the delicate balance of forces where the glacier fronts meet the ocean could trigger the changes. Faezeh Nick and colleagues5 present ice-sheet modeling experiments that mimic the observations on Helheim glacier, East Greenland, and suggest that the dynamic behaviour of outlet glaciers follows from perturbations at their marine fronts. Greenland's ice sheet loses mass partly through surface melting and partly through fast flowing outlet glaciers that connect the vast plateau of inland ice with the ocean. Earlier ice sheet models have failed to reproduce the dynamic variability exhibited by ice sheets over time. It has therefore not been possible to distinguish with confidence between basal lubrication from surface meltwater and changes at the glaciers' marine fronts as causes for the observed changes on Greenland's outlet glaciers. But this distinction bears directly on future sea-level rise, the raison d'etre of much of modern-day glaciology: If the recent dynamic mass loss Greenland's outlet glaciers is linked to changing atmospheric temperatures, it may continue for as long as temperatures continue to increase. On the other hand, if the source of the dynamic mass loss is a perturbation at the ice-ocean boundary, these glaciers will lose contact with that perturbation after a finite

  9. Advances in neutron radiographic techniques and applications: a method for nondestructive testing.

    PubMed

    Berger, Harold

    2004-10-01

    A brief history of neutron radiography is presented to set the stage for a discussion of significant neutron radiographic developments and an assessment of future directions for neutron radiography. Specific advances are seen in the use of modern, high dynamic range imaging methods (image plates and flat panels) and for high contrast techniques such as phase contrast, and phase-sensitive imaging. Competition for neutron radiographic inspection may develop as these techniques offer application prospects for X-ray methods.

  10. Technology Alignment and Portfolio Prioritization (TAPP): Advanced Methods in Strategic Analysis, Technology Forecasting and Long Term Planning for Human Exploration and Operations, Advanced Exploration Systems and Advanced Concepts

    NASA Technical Reports Server (NTRS)

    Funaro, Gregory V.; Alexander, Reginald A.

    2015-01-01

    The Advanced Concepts Office (ACO) at NASA, Marshall Space Flight Center is expanding its current technology assessment methodologies. ACO is developing a framework called TAPP that uses a variety of methods, such as association mining and rule learning from data mining, structure development using a Technological Innovation System (TIS), and social network modeling to measure structural relationships. The role of ACO is to 1) produce a broad spectrum of ideas and alternatives for a variety of NASA's missions, 2) determine mission architecture feasibility and appropriateness to NASA's strategic plans, and 3) define a project in enough detail to establish an initial baseline capable of meeting mission objectives ACO's role supports the decision­-making process associated with the maturation of concepts for traveling through, living in, and understanding space. ACO performs concept studies and technology assessments to determine the degree of alignment between mission objectives and new technologies. The first step in technology assessment is to identify the current technology maturity in terms of a technology readiness level (TRL). The second step is to determine the difficulty associated with advancing a technology from one state to the next state. NASA has used TRLs since 1970 and ACO formalized them in 1995. The DoD, ESA, Oil & Gas, and DoE have adopted TRLs as a means to assess technology maturity. However, "with the emergence of more complex systems and system of systems, it has been increasingly recognized that TRL assessments have limitations, especially when considering [the] integration of complex systems." When performing the second step in a technology assessment, NASA requires that an Advancement Degree of Difficulty (AD2) method be utilized. NASA has used and developed or used a variety of methods to perform this step: Expert Opinion or Delphi Approach, Value Engineering or Value Stream, Analytical Hierarchy Process (AHP), Technique for the Order of

  11. Study on the Integrated Geophysic Methods and Application of Advanced Geological Detection for Complicated Tunnel

    NASA Astrophysics Data System (ADS)

    Zhou, L.; Xiao, G.

    2014-12-01

    The engineering geological and hydrological conditions of current tunnels are more and more complicated, as the tunnels are elongated with deeper depth. In constructing these complicated tunnels, geological hazards prone to occur as induced by unfavorable geological bodies, such as fault zones, karst or hydrous structures, etc. The working emphasis and difficulty of the advanced geological exploration for complicated tunnels are mainly focused on the structure and water content of these unfavorable geological bodies. The technical aspects of my paper systematically studied the advanced geological exploration theory and application aspects for complicated tunnels, with discussion on the key technical points and useful conclusions. For the all-aroundness and accuracy of advanced geological exploration results, the objective of my paper is targeted on the comprehensive examination on the structure and hydrous characteristic of the unfavorable geological bodies in complicated tunnels. By the multi-component seismic modeling on a more real model containing the air medium, the wave field response characteristics of unfavorable geological bodies can be analyzed, thus providing theoretical foundation for the observation system layout, signal processing and interpretation of seismic methods. Based on the tomographic imaging theory of seismic and electromagnetic method, 2D integrated seismic and electromagnetic tomographic imaging and visualization software was designed and applied in the advanced drilling hole in the tunnel face, after validation of the forward and inverse modeling results on theoretical models. The transmission wave imaging technology introduced in my paper can be served as a new criterion for detection of unfavorable geological bodies. After careful study on the basic theory, data processing and interpretation, practical applications of TSP and ground penetrating radar (GPR) method, as well as serious examination on their application examples, my paper

  12. Advanced fire-resistant forms of activated carbon and methods of adsorbing and separating gases using same

    SciTech Connect

    Xiong, Yongliang; Wang, Yifeng

    2016-04-19

    A method of removing a target gas from a gas stream is disclosed. The method uses advanced, fire-resistant activated carbon compositions having vastly improved fire resistance. Methods for synthesizing the compositions are also provided. The advanced compositions have high gas adsorption capacities and rapid adsorption kinetics (comparable to commercially-available activated carbon), without having any intrinsic fire hazard.

  13. Recent Advances in the Method of Forces: Integrated Force Method of Structural Analysis

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya N.; Coroneos, Rula M.; Hopkins, Dale A.

    1998-01-01

    Stress that can be induced in an elastic continuum can be determined directly through the simultaneous application of the equilibrium equations and the compatibility conditions. In the literature, this direct stress formulation is referred to as the integrated force method. This method, which uses forces as the primary unknowns, complements the popular equilibrium-based stiffness method, which considers displacements as the unknowns. The integrated force method produces accurate stress, displacement, and frequency results even for modest finite element models. This version of the force method should be developed as an alternative to the stiffness method because the latter method, which has been researched for the past several decades, may have entered its developmental plateau. Stress plays a primary role in the development of aerospace and other products, and its analysis is difficult. Therefore, it is advisable to use both methods to calculate stress and eliminate errors through comparison. This paper examines the role of the integrated force method in analysis, animation and design.

  14. Slow Progress in Dune (Left Front Wheel)

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The left front wheel of NASA's Mars Exploration Rover Opportunity makes slow but steady progress through soft dune material in this movie clip of frames taken by the rover's front hazard identification camera over a period of several days. The sequence starts on Opportunity's 460th martian day, or sol (May 10, 2005) and ends 11 days later. In eight drives during that period, Opportunity advanced a total of 26 centimeters (10 inches) while spinning its wheels enough to have driven 46 meters (151 feet) if there were no slippage. The motion appears to speed up near the end of the clip, but that is an artifact of individual frames being taken less frequently.

  15. Slow Progress in Dune (Right Front Wheel)

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The right front wheel of NASA's Mars Exploration Rover Opportunity makes slow but steady progress through soft dune material in this movie clip of frames taken by the rover's front hazard identification camera over a period of several days. The sequence starts on Opportunity's 460th martian day, or sol (May 10, 2005) and ends 11 days later. In eight drives during that period, Opportunity advanced a total of 26 centimeters (10 inches) while spinning its wheels enough to have driven 46 meters (151 feet) if there were no slippage. The motion appears to speed up near the end of the clip, but that is an artifact of individual frames being taken less frequently.

  16. On a front line.

    PubMed Central

    Jones, L.

    1995-01-01

    Like the patients, doctors in Sarajevo depend largely on humanitarian aid; everyone in the public sector has worked without pay for almost three years. The hospital is on a front line; yet the psychiatric department continues to function, even conducting large scale studies of psychosocial aspects of war in Bosnia-Hercegovina. The type of inpatient morbidity and treatment patterns have changed. A plethora of psychosocial rehabilitation programmes has emerged, including counselling, drop in centres, and attending to special needs of elderly people, schoolchildren, and women. The most prominent psychological symptoms were exhaustion at the prospect of a third winter of war and bewilderment at the Western stereotype of Bosnians as Muslim fundamentalists. Images p1052-a p1053-a PMID:7728062

  17. Light-Front Holographic QCD

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.; /Costa Rica U.

    2012-02-16

    The relation between the hadronic short-distance constituent quark and gluon particle limit and the long-range confining domain is yet one of the most challenging aspects of particle physics due to the strong coupling nature of Quantum Chromodynamics, the fundamental theory of the strong interactions. The central question is how one can compute hadronic properties from first principles; i.e., directly from the QCD Lagrangian. The most successful theoretical approach thus far has been to quantize QCD on discrete lattices in Euclidean space-time. Lattice numerical results follow from computation of frame-dependent moments of distributions in Euclidean space and dynamical observables in Minkowski spacetime, such as the time-like hadronic form factors, are not amenable to Euclidean lattice computations. The Dyson-Schwinger methods have led to many important insights, such as the infrared fixed point behavior of the strong coupling constant, but in practice, the analyses are limited to ladder approximation in Landau gauge. Baryon spectroscopy and the excitation dynamics of nucleon resonances encoded in the nucleon transition form factors can provide fundamental insight into the strong-coupling dynamics of QCD. New theoretical tools are thus of primary interest for the interpretation of the results expected at the new mass scale and kinematic regions accessible to the JLab 12 GeV Upgrade Project. The AdS/CFT correspondence between gravity or string theory on a higher-dimensional anti-de Sitter (AdS) space and conformal field theories in physical space-time has led to a semiclassical approximation for strongly-coupled QCD, which provides physical insights into its nonperturbative dynamics. The correspondence is holographic in the sense that it determines a duality between theories in different number of space-time dimensions. This geometric approach leads in fact to a simple analytical and phenomenologically compelling nonperturbative approximation to the full light-front

  18. Advanced Life Analysis Methods. Volume 2. Crack Growth Analysis Methods for Attachment Lugs

    DTIC Science & Technology

    1984-09-01

    GROUP SUB. GR. ,ttachment Lugs, Cracking, Aircraft, Damage Tolerance, 3 Analysis Methods, Straight Lugs, Tapered Lugs, Stresses, .3 3 Stress Intensity...the damage tolerance of aircraft attachment lugs are developed and presented. Stress and fracture analyses are conducted for simple male straight...Parameter Weight Function Approximation 78 3.3 Three-Dimensional Cracked Finite Element Method 85 4. Elastoplastic Analysis 100 IV STRESS INTENSITY FACTORS

  19. FACILITY 1042. FRONT OBLIQUE SHOWING ROYAL PALMS LINING FRONT WALK. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 1042. FRONT OBLIQUE SHOWING ROYAL PALMS LINING FRONT WALK. VIEW FACING SOUTHEAST - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hale Alii, Junior Officers' Quarters Type, 9-10 Hale Alii Avenue, 1-2 Eighth Street, Pearl City, Honolulu County, HI

  20. Left ventricular flow analysis: recent advances in numerical methods and applications in cardiac ultrasound.

    PubMed

    Borazjani, Iman; Westerdale, John; McMahon, Eileen M; Rajaraman, Prathish K; Heys, Jeffrey J; Belohlavek, Marek

    2013-01-01

    The left ventricle (LV) pumps oxygenated blood from the lungs to the rest of the body through systemic circulation. The efficiency of such a pumping function is dependent on blood flow within the LV chamber. It is therefore crucial to accurately characterize LV hemodynamics. Improved understanding of LV hemodynamics is expected to provide important clinical diagnostic and prognostic information. We review the recent advances in numerical and experimental methods for characterizing LV flows and focus on analysis of intraventricular flow fields by echocardiographic particle image velocimetry (echo-PIV), due to its potential for broad and practical utility. Future research directions to advance patient-specific LV simulations include development of methods capable of resolving heart valves, higher temporal resolution, automated generation of three-dimensional (3D) geometry, and incorporating actual flow measurements into the numerical solution of the 3D cardiovascular fluid dynamics.

  1. Left Ventricular Flow Analysis: Recent Advances in Numerical Methods and Applications in Cardiac Ultrasound

    PubMed Central

    Borazjani, Iman; Westerdale, John; McMahon, Eileen M.; Rajaraman, Prathish K.; Heys, Jeffrey J.

    2013-01-01

    The left ventricle (LV) pumps oxygenated blood from the lungs to the rest of the body through systemic circulation. The efficiency of such a pumping function is dependent on blood flow within the LV chamber. It is therefore crucial to accurately characterize LV hemodynamics. Improved understanding of LV hemodynamics is expected to provide important clinical diagnostic and prognostic information. We review the recent advances in numerical and experimental methods for characterizing LV flows and focus on analysis of intraventricular flow fields by echocardiographic particle image velocimetry (echo-PIV), due to its potential for broad and practical utility. Future research directions to advance patient-specific LV simulations include development of methods capable of resolving heart valves, higher temporal resolution, automated generation of three-dimensional (3D) geometry, and incorporating actual flow measurements into the numerical solution of the 3D cardiovascular fluid dynamics. PMID:23690874

  2. Application of Advanced Methods to Predict Grid to Rod Fretting in PWRs

    SciTech Connect

    Karoutas, Zeses; Roger, Lu Y.; Yan, J.; Krammen, M.A.; Sham, Sam

    2012-01-01

    Advanced modeling and simulation methods are being developed as part of the US Department of Energy sponsored Nuclear Energy Modeling and Simulation Hub called CASL (Consortium for Advanced Simulation of LWRs). The key participants of the CASL team include Oak Ridge National Laboratory (lead), Idaho National Laboratory, Sandia National Laboratories, Los Alamos National Laboratory, Massachusetts Institute of Technology, North Carolina State University, University of Michigan, Electric Power Research Institute, Tennessee Valley Authority and Westinghouse Electric Corporation. One of the key objectives of the CASL program is to develop multi-physics methods and tools which evaluate neutronic, thermal-hydraulic, structural mechanics and nuclear fuel rod performance in rod bundles to support power uprates, increased burnup/cycle length and life extension for US nuclear plants.

  3. Recent advances on the encoding and selection methods of DNA-encoded chemical library.

    PubMed

    Shi, Bingbing; Zhou, Yu; Huang, Yiran; Zhang, Jianfu; Li, Xiaoyu

    2017-02-01

    DNA-encoded chemical library (DEL) has emerged as a powerful and versatile tool for ligand discovery in chemical biology research and in drug discovery. Encoding and selection methods are two of the most important technological aspects of DEL that can dictate the performance and utilities of DELs. In this digest, we have summarized recent advances on the encoding and selection strategies of DEL and also discussed the latest developments on DNA-encoded dynamic library, a new frontier in DEL research.

  4. Advanced methods and means to improve atmospheric lidar stability against sky background clutter

    NASA Astrophysics Data System (ADS)

    Agishev, Ravil R.

    2011-11-01

    An impact of intensive background clutter on lidar photodetectors leads to changes of their sensitivity and can even overload them. As a result, information on atmospheric optical parameters is distorted and sometimes can be completely lost. Since a problem of lidar system structure and parameters adaptation to background radiation remains actual one, some advanced methods and means to improve atmospheric lidar stability against sky background clutter are discussed.

  5. MSFC Advanced Concepts Office and the Iterative Launch Vehicle Concept Method

    NASA Technical Reports Server (NTRS)

    Creech, Dennis

    2011-01-01

    This slide presentation reviews the work of the Advanced Concepts Office (ACO) at Marshall Space Flight Center (MSFC) with particular emphasis on the method used to model launch vehicles using INTegrated ROcket Sizing (INTROS), a modeling system that assists in establishing the launch concept design, and stage sizing, and facilitates the integration of exterior analytic efforts, vehicle architecture studies, and technology and system trades and parameter sensitivities.

  6. A Preliminary Analysis of Advance Appropriations as a Budgeting Method for Navy Ship Procurements

    DTIC Science & Technology

    2002-02-01

    Irv Blickstein • Giles Smith R A Preliminary Analysis of ADVANCE APPROPRIATIONS as a Budgeting Method for Navy Ship Procurements National Defense ...conducted for the U.S. Navy within the Acquisition and Technology Policy Center of RAND’s National Defense Research Institute, a federally funded...research and development center supported by the Office of the Secretary of Defense , the Joint Staff, the unified commands, and the defense agencies under

  7. Development and application of a probabilistic evaluation method for advanced process technologies. Final report

    SciTech Connect

    Frey, H.C.; Rubin, E.S.

    1991-04-01

    The objective of this work is to develop and apply a method for research planning for advanced process technologies. To satisfy requirements for research planning, it is necessary to: (1) identify robust solutions to process design questions in the face of uncertainty to eliminate inferior design options; (2) identify key problem areas in a technology that should be the focus of further research to reduce the risk of technology failure; (3) compare competing technologies on a consistent basis to determine the risks associated with adopting a new technology; and (4) evaluate the effects that additional research might have on comparisons with conventional technology. An important class of process technologies are electric power plants. In particular, advanced clean coal technologies are expected to play a key role in the energy and environmental future of the US, as well as in other countries. Research planning for advanced clean coal technology development is an important part of energy and environmental policy. Thus, the research planning method developed here is applied to case studies focusing on a specific clean coal technology. The purpose of the case studies is both to demonstrate the research planning method and to obtain technology-specific conclusions regarding research strategies.

  8. Development and application of a probabilistic evaluation method for advanced process technologies

    SciTech Connect

    Frey, H.C.; Rubin, E.S.

    1991-04-01

    The objective of this work is to develop and apply a method for research planning for advanced process technologies. To satisfy requirements for research planning, it is necessary to: (1) identify robust solutions to process design questions in the face of uncertainty to eliminate inferior design options; (2) identify key problem areas in a technology that should be the focus of further research to reduce the risk of technology failure; (3) compare competing technologies on a consistent basis to determine the risks associated with adopting a new technology; and (4) evaluate the effects that additional research might have on comparisons with conventional technology. An important class of process technologies are electric power plants. In particular, advanced clean coal technologies are expected to play a key role in the energy and environmental future of the US, as well as in other countries. Research planning for advanced clean coal technology development is an important part of energy and environmental policy. Thus, the research planning method developed here is applied to case studies focusing on a specific clean coal technology. The purpose of the case studies is both to demonstrate the research planning method and to obtain technology-specific conclusions regarding research strategies.

  9. Surface properties of ocean fronts

    NASA Technical Reports Server (NTRS)

    Wolff, P. M.; Hubert, W. E.

    1976-01-01

    Background information on oceanic fronts is presented and the results of several models which were developed to study the dynamics of oceanic fronts and their effects on various surface properties are described. The details of the four numerical models used in these studies are given in separate appendices which contain all of the physical equations, program documentation and running instructions for the models.

  10. Snowplow Injection Front Effects

    NASA Technical Reports Server (NTRS)

    Moore, T. E.; Chandler, M. O.; Buzulukova, N.; Collinson, G. A.; Kepko, E. L.; Garcia-Sage, K. S.; Henderson, M. G.; Sitnov, M. I.

    2013-01-01

    As the Polar spacecraft apogee precessed through the magnetic equator in 2001, Polar encountered numerous substorm events in the region between geosynchronous orbit and 10 RE geocentric distance; most of them in the plasma sheet boundary layers. Of these, a small number was recorded near the neutral sheet in the evening sector. Polar/Thermal Ion Dynamics Experiment provides a unique perspective on the lowest-energy ion plasma, showing that these events exhibited a damped wavelike character, initiated by a burst of radially outward flow transverse to the local magnetic field at approximately 80 km/s. They then exhibit strongly damped cycles of inward/outward flow with a period of several minutes. After one or two cycles, they culminated in a hot plasma electron and ion injection, quite similar to those observed at geosynchronous orbit. Cold plasmaspheric plasmas comprise the outward flow cycles, while the inward flow cycles contain counterstreaming field-parallel polar wind-like flows. The observed wavelike structure, preceding the arrival of an earthward moving substorm injection front, suggests an outward displacement driven by the inward motion at local times closer to midnight, that is, a "snowplow" effect. The damped in/out flows are consistent with interchange oscillations driven by the arrival at the observed local time by an injection originating at greater radius and local time.

  11. Comparison of advanced reduced-basis methods for transient structural analysis

    NASA Technical Reports Server (NTRS)

    Mcgowan, David M.; Bostic, Susan W.

    1991-01-01

    Two advanced reduced-basis methods for linear, transient structural analysis, the force-derivative method and the Lanczos method, are compared to two widely-used modal methods, the mode-displacement method and the mode-acceleration method. Comparisons are made for two linear example problems: a proportionally-damped cantilevered beam subject to a discrete tip load which varies linearly with time, and a discretely-damped multispan beam subject to a uniformly distributed load which varies as a quintic function of time. Results from the methods are compared in terms of the number of basis vectors required to obtain a desired level of accuracy and the associated computational times. The results are problem dependent, and it is shown that for the cantilevered beam problem, the mode-acceleration and force-derivative methods are the most efficient in terms of the number of basis vectors and computational time. The force-derivative method is shown to be the most effective method for solving the multispan beam problem with closely-spaced frequencies. In general, the force-derivative method is shown to produce an accurate solution using very few basis vectors and to require less computational time as compared to the other methods studied.

  12. Advanced Life Analysis Methods. Volume 3. Experimental Evaluation of Crack Growth Analysis Methods for Attachment Lugs

    DTIC Science & Technology

    1984-09-17

    Structural Lugs 10 6.00 TETM TESX, MARI LOCKHEED L𔃼.0 GRUP IIhA AND 2Rii * 2~~~~.0 .RUPINI .01 .05 1 .2 .5. 9 99PROABLTY F*ý,r 1-40 4oprsno R ato nTs rga...monitor loads and perform failsafe functions . A sinewave function generator provides load commands to the servo loop and a calibrated amplitude measurement...Simple Compounding Solution o 2-D Cracked Finite Element Procedure o Green’s Function Method 0 3-D Cracked Finite Element PrTocedure Parameters and

  13. Advanced Numerical methods for F. E. Simulation of Metal Forming Processes

    NASA Astrophysics Data System (ADS)

    Chenot, Jean-Loup; Bernacki, Marc; Fourment, Lionel; Ducloux, Richard

    2010-06-01

    The classical scientific basis for finite element modeling of metal forming processes is first recalled. Several developments in advanced topics are summarized: adaptive and anisotropic remeshing, parallel solving, multi material deformation. More recent researches in numerical analysis are outlined, including multi grid and multi mesh methods, mainly devoted to decrease computation time, automatic optimization method for faster and more effective design of forming processes. The link of forming simulation and structural computations is considered with emphasis on the necessity to predict the final mechanical properties. Finally a brief account of computation at the micro scale level is given.

  14. A framework for advanced methods of control of human-induced vibrations

    NASA Astrophysics Data System (ADS)

    Reynolds, Paul

    2012-04-01

    The vibration serviceability of civil engineering structures under human dynamic excitation is becoming ever more critical with the design and redevelopment of structures with reduced mass, stiffness and damping. A large number of problems have been reported in floors, footbridges, sports stadia, staircases and other structures. Unfortunately, the range of options available to fix such problems are very limited and are primarily limited to structural modification or the implementation of passive vibration control measures, such as tuned mass dampers. This paper presents the initial development of a new framework for advanced methods of control of humaninduced vibrations in civil engineering structures. This framework includes both existing passive methods of vibration control and more advanced active, semi-active and hybrid control techniques, which may be further developed as practical solutions for these problems. Through the use of this framework, rational decisions as to the most appropriate technologies for particular human vibration problems may be made and pursued further. This framework is also intended to be used in the design of new civil engineering structures, where advanced control technologies may be used both to increase the achievable slenderness and to reduce the amount of construction materials used and hence their embodied energy. This will be an ever more important consideration with the current drive for structures with reduced environmental impact.

  15. Selenium contaminated waters: An overview of analytical methods, treatment options and recent advances in sorption methods.

    PubMed

    Santos, Sílvia; Ungureanu, Gabriela; Boaventura, Rui; Botelho, Cidália

    2015-07-15

    Selenium is an essential trace element for many organisms, including humans, but it is bioaccumulative and toxic at higher than homeostatic levels. Both selenium deficiency and toxicity are problems around the world. Mines, coal-fired power plants, oil refineries and agriculture are important examples of anthropogenic sources, generating contaminated waters and wastewaters. For reasons of human health and ecotoxicity, selenium concentration has to be controlled in drinking-water and in wastewater, as it is a potential pollutant of water bodies. This review article provides firstly a general overview about selenium distribution, sources, chemistry, toxicity and environmental impact. Analytical techniques used for Se determination and speciation and water and wastewater treatment options are reviewed. In particular, published works on adsorption as a treatment method for Se removal from aqueous solutions are critically analyzed. Recent published literature has given particular attention to the development and search for effective adsorbents, including low-cost alternative materials. Published works mostly consist in exploratory findings and laboratory-scale experiments. Binary metal oxides and LDHs (layered double hydroxides) have presented excellent adsorption capacities for selenium species. Unconventional sorbents (algae, agricultural wastes and other biomaterials), in raw or modified forms, have also led to very interesting results with the advantage of their availability and low-cost. Some directions to be considered in future works are also suggested.

  16. Experimental method for determination of bending and torsional rigidities of advanced composite laminates

    SciTech Connect

    Maeda, Takenori

    1995-11-01

    This paper presents an experimental method for the determination of the bending and torsional rigidities of advanced fiber composite laminates with the aid of laser holographic interferometry. The proposed method consists of a four-point bending test and a resonance test. The bending rigidity ratio (D{sub 12}/D{sub 22}) can be determined from the fringe patterns of the four-point bending test. The bending rigidities (D{sub 11} and D{sub 22}) and the torsional rigidity (D{sub 66}) are calculated from the natural frequencies of cantilever plates of the resonance test. The test specimens are carbon/epoxy cross-ply laminates. The adequacy of the experimental method is confirmed by comparing the measured rigidities with the theoretical values obtained from classical lamination theory (CLT) by using the measured tensile properties. The results show that the present method can be used to evaluate the rigidities of orthotropic laminates with reasonably good accuracy.

  17. The promise of mixed-methods for advancing latino health research.

    PubMed

    Apesoa-Varano, Ester Carolina; Hinton, Ladson

    2013-09-01

    Mixed-methods research in the social sciences has been conducted for quite some time. More recently, mixed-methods have become popular in health research, with the National Institutes of Health leading the impetus to fund studies that implement such an approach. The public health issues facing us today are great and they range from policy and other macro-level issues, to systems level problems to individuals' health behaviors. For Latinos, who are projected to become the largest minority group bearing a great deal of the burden of social inequality in the U.S., it is important to understand the deeply-rooted nature of these health disparities in order to close the gap in health outcomes. Mixed-methodology thus holds promise for advancing research on Latino heath by tackling health disparities from a variety of standpoints and approaches. The aim of this manuscript is to provide two examples of mixed methods research, each of which addresses a health topic of considerable importance to older Latinos and their families. These two examples will illustrate a) the complementary use of qualitative and quantitative methods to advance health of older Latinos in an area that is important from a public health perspective, and b) the "translation" of findings from observational studies (informed by social science and medicine) to the development and testing of interventions.

  18. The Promise of Mixed-Methods for Advancing Latino Health Research

    PubMed Central

    Apesoa-Varano, Ester Carolina; Hinton, Ladson

    2015-01-01

    Mixed-methods research in the social sciences has been conducted for quite some time. More recently, mixed-methods have become popular in health research, with the National Institutes of Health leading the impetus to fund studies that implement such an approach. The public health issues facing us today are great and they range from policy and other macro-level issues, to systems level problems to individuals' health behaviors. For Latinos, who are projected to become the largest minority group bearing a great deal of the burden of social inequality in the U.S., it is important to understand the deeply-rooted nature of these health disparities in order to close the gap in health outcomes. Mixed-methodology thus holds promise for advancing research on Latino heath by tackling health disparities from a variety of standpoints and approaches. The aim of this manuscript is to provide two examples of mixed methods research, each of which addresses a health topic of considerable importance to older Latinos and their families. These two examples will illustrate a) the complementary use of qualitative and quantitative methods to advance health of older Latinos in an area that is important from a public health perspective, and b) the “translation” of findings from observational studies (informed by social science and medicine) to the development and testing of interventions. PMID:23996325

  19. Asymmetric counterpropagating fronts without flow

    NASA Astrophysics Data System (ADS)

    Andrade-Silva, I.; Clerc, M. G.; Odent, V.

    2015-06-01

    Out-of-equilibrium systems exhibit domain walls between different states. These walls, depending on the type of connected states, can display rich spatiotemporal dynamics. In this Rapid Communication, we investigate the asymmetrical counterpropagation of fronts in an in-plane-switching cell filled with a nematic liquid crystal. Experimentally, we characterize the different front shapes and propagation speeds. These fronts present dissimilar elastic deformations that are responsible for their asymmetric speeds. Theoretically, using a phenomenological model, we describe the observed dynamics with fair agreement.

  20. Asymmetric counterpropagating fronts without flow.

    PubMed

    Andrade-Silva, I; Clerc, M G; Odent, V

    2015-06-01

    Out-of-equilibrium systems exhibit domain walls between different states. These walls, depending on the type of connected states, can display rich spatiotemporal dynamics. In this Rapid Communication, we investigate the asymmetrical counterpropagation of fronts in an in-plane-switching cell filled with a nematic liquid crystal. Experimentally, we characterize the different front shapes and propagation speeds. These fronts present dissimilar elastic deformations that are responsible for their asymmetric speeds. Theoretically, using a phenomenological model, we describe the observed dynamics with fair agreement.

  1. [Front Block distraction].

    PubMed

    Esnault, Olivier

    2015-03-01

    The contribution of the segmental osteotomies in the ortho-surgical protocols is no longer to demonstrate and found a new lease of life thanks to the combination with the bone distraction techniques. The osteotomy of Köle, initially described to close infraclusies, and then used to level very marked curves of Spee has more recently been used to correct anterior crowding. This support is therefore aimed at patients with an incisor and canine Class 2 but molar Class 1 with an isolated mandibular footprint. With minimal orthodontic preparation we can create in two weeks bilateral diastemas that will then be used to align the incisivocanin crowding without stripping or bicuspid extractions. Dental orthodontic movements can be resumed one month after the end of the distraction. This technique is therefore likely to avoid bicuspid extraction and replace some sagittal osteotomy advancement by correction of the overjet. It also helps to correct a incisors labial or lingual tipping playing on differential activation of the cylinders and the distractor. This segmental surgery can be combined with Le Fort 1 surgeries with correction of the transverse and associated meanings, but in a second time, to a mandibular advancement and/or a genioplasty.

  2. Structural Analysis and Quantitative Determination of Clevidipine Butyrate Impurities Using an Advanced RP-HPLC Method.

    PubMed

    Zhou, Yuxia; Zhou, Fan; Yan, Fei; Yang, Feng; Yao, Yuxian; Zou, Qiaogen

    2016-03-01

    Eleven potential impurities, including process-related compounds and degradation products, have been analyzed by comprehensive studies on the manufacturing process of clevidipine butyrate. Possible formation mechanisms could also be devised. MS and NMR techniques have been used for the structural characterization of three previously unreported impurities (Imp-3, Imp-5 and Imp-11). To separate and quantify the potential impurities in a simultaneous fashion, an efficient and advanced RP-HPLC method has been developed. In doing so, four major degradation products (Imp-2, Imp-4, Imp-8 and Imp-10) can be observed under varying stress conditions. This analytical method has been validated according to ICH guidelines with respect to specificity, accuracy, linearity, robustness and stability. The method described has been demonstrated to be applicable in routine quality control processes and stability evaluation studies of clevidipine butyrate.

  3. Prediction and preliminary standardization of fire debris constituents with the advanced distillation curve method.

    PubMed

    Bruno, Thomas J; Lovestead, Tara M; Huber, Marcia L

    2011-01-01

    The recent National Academy of Sciences report on forensic sciences states that the study of fire patterns and debris in arson fires is in need of additional work and eventual standardization. We discuss a recently introduced method that can provide predicted evaporation patterns for ignitable liquids as a function of temperature. The method is a complex fluid analysis protocol, the advanced distillation curve approach, featuring a composition explicit data channel for each distillate fraction (for qualitative, quantitative, and trace analysis), low uncertainty temperature measurements that are thermodynamic state points that can be modeled with an equation of state, consistency with a century of historical data, and an assessment of the energy content of each distillate fraction. We discuss the application of the method to kerosenes and gasolines and outline how expansion of the scope of fluids to other ignitable liquids can benefit the criminalist in the analysis of fire debris for arson.

  4. Immunoassay Methods and their Applications in Pharmaceutical Analysis: Basic Methodology and Recent Advances.

    PubMed

    Darwish, Ibrahim A

    2006-09-01

    Immunoassays are bioanalytical methods in which the quantitation of the analyte depends on the reaction of an antigen (analyte) and an antibody. Immunoassays have been widely used in many important areas of pharmaceutical analysis such as diagnosis of diseases, therapeutic drug monitoring, clinical pharmacokinetic and bioequivalence studies in drug discovery and pharmaceutical industries. The importance and widespread of immunoassay methods in pharmaceutical analysis are attributed to their inherent specificity, high-throughput, and high sensitivity for the analysis of wide range of analytes in biological samples. Recently, marked improvements were achieved in the field of immunoassay development for the purposes of pharmaceutical analysis. These improvements involved the preparation of the unique immunoanalytical reagents, analysis of new categories of compounds, methodology, and instrumentation. The basic methodologies and recent advances in immunoassay methods applied in different fields of pharmaceutical analysis have been reviewed.

  5. A complex method of equipment replacement planning. An advanced plan for the replacement of medical equipment.

    PubMed

    Dondelinger, Robert M

    2004-01-01

    This complex method of equipment replacement planning is a methodology; it is a means to an end, a process that focuses on equipment most in need of replacement, rather than the end itself. It uses data available from the maintenance management database, and attempts to quantify those subjective items important [figure: see text] in making equipment replacement decisions. Like the simple method of the last issue, it is a starting point--albeit an advanced starting point--which the user can modify to fit their particular organization, but the complex method leaves room for expansion. It is based on sound logic, documented facts, and is fully defensible during the decision-making process and will serve your organization well as provide a structure for your equipment replacement planning decisions.

  6. Advanced Multifunctional Properties of Aligned Carbon Nanotube-Epoxy Composites from Carbon Nanotube Aerogel Method

    NASA Astrophysics Data System (ADS)

    Tran, Thang; Liu, Peng; Fan, Zeng; Ngern, Nigel; Duong, Hai

    2015-03-01

    Unlike previous methods of making carbon nanotube (CNT) thin films, aligned CNT thin films in this work are synthesized directly from CNT aerogels in a CVD process. CH4/H2/He gases and ferrocene/thiophene catalysts are mixed and reacted in the reactor at 1200 °C to form CNT aerogel socks. By pulling out the socks with a metal rod, CNT thin films with 15-nm diameter MWNTs are aligned and produced continuously at a speed of a few meters per minute. The number of the aligned CNT thin film layers/ thickness can also be controlled well. The as-synthesized aligned CNT films are further condensed by acetone spray and post-treated by UV light. The aligned CNT films without any above post-treatment have a high electrical conductivity of 400S/cm. We also develop aligned CNT-epoxy composites by infiltrating epoxy into the above aligned CNT thin films using Vacuum Assisted Resin Transfer Molding (VARTM) method. Our cost-effective fabrication method of the aligned CNT films is more advanced for developing the composites having CNT orientation control. The mechanical, electrical and optical properties of the aligned CNT epoxy composites are measured. About 2% of the aligned CNTs can enhance significantly the electrical conductivity and hardness of aligned CNT-epoxy composite films. Effects of morphologies, volume fraction, and alignment of the CNTs on the advanced multifunctional properties of the aligned CNT-epoxy composites are also quantified.

  7. Application of advanced multidisciplinary analysis and optimization methods to vehicle design synthesis

    NASA Technical Reports Server (NTRS)

    Consoli, Robert David; Sobieszczanski-Sobieski, Jaroslaw

    1990-01-01

    Advanced multidisciplinary analysis and optimization methods, namely system sensitivity analysis and non-hierarchical system decomposition, are applied to reduce the cost and improve the visibility of an automated vehicle design synthesis process. This process is inherently complex due to the large number of functional disciplines and associated interdisciplinary couplings. Recent developments in system sensitivity analysis as applied to complex non-hierarchic multidisciplinary design optimization problems enable the decomposition of these complex interactions into sub-processes that can be evaluated in parallel. The application of these techniques results in significant cost, accuracy, and visibility benefits for the entire design synthesis process.

  8. Front tracking for characterizing and quantifying reactive mixing

    NASA Astrophysics Data System (ADS)

    Kelley, Douglas; Nevins, Thomas

    2016-11-01

    Mixing in industrial chemical reactors involves complicated interactions between advection, reaction, and diffusion that are difficult to simulate or measure in detail. However, in large-Damköhler-number systems which show sharp fronts between reacted and unreacted regions, reactor dynamics might be more simply and usefully characterized in terms of the reaction fronts themselves. In fact, prior work has already shown that the reaction rate and material diffusivity can be calculated directly if front speed and front thickness are known. We have developed methods to optically track reaction fronts, measuring their speed and thickness throughout space and time. We will present such measurements in both simulation and experiment, consider their statistics, and discuss future efforts to characterize and quantify mixing in chemical reactors.

  9. Pareto-front shape in multiobservable quantum control

    NASA Astrophysics Data System (ADS)

    Sun, Qiuyang; Wu, Re-Bing; Rabitz, Herschel

    2017-03-01

    Many scenarios in the sciences and engineering require simultaneous optimization of multiple objective functions, which are usually conflicting or competing. In such problems the Pareto front, where none of the individual objectives can be further improved without degrading some others, shows the tradeoff relations between the competing objectives. This paper analyzes the Pareto-front shape for the problem of quantum multiobservable control, i.e., optimizing the expectation values of multiple observables in the same quantum system. Analytic and numerical results demonstrate that with two commuting observables the Pareto front is a convex polygon consisting of flat segments only, while with noncommuting observables the Pareto front includes convexly curved segments. We also assess the capability of a weighted-sum method to continuously capture the points along the Pareto front. Illustrative examples with realistic physical conditions are presented, including NMR control experiments on a 1H-13C two-spin system with two commuting or noncommuting observables.

  10. 4. CONSTRUCTION PROGRESS VIEW OF EQUIPMENT IN FRONT PART OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. CONSTRUCTION PROGRESS VIEW OF EQUIPMENT IN FRONT PART OF CONTROL BUNKER (TRANSFORMER, HYDRAULIC TANK, PUMP, MOTOR). SHOWS UNLINED CORRUGATED METAL WALL. CAMERA FACING EAST. INEL PHOTO NUMBER 65-5433, TAKEN OCTOBER 20, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

  11. Spinning the Web: The Design of Yale's Front Door.

    ERIC Educational Resources Information Center

    Callum, Robert

    1996-01-01

    The process of designing the Yale University (Connecticut) World Wide Web page "front door" is described, including its conceptualization, evolution through technological advances and attitudinal change, achievement of consensus through an interdepartmental advisory team, constituency response, and expectations about future change. (MSE)

  12. Front interaction induces excitable behavior

    NASA Astrophysics Data System (ADS)

    Parra-Rivas, P.; Matías, M. A.; Colet, P.; Gelens, L.; Walgraef, D.; Gomila, D.

    2017-02-01

    Spatially extended systems can support local transient excitations in which just a part of the system is excited. The mechanisms reported so far are local excitability and excitation of a localized structure. Here we introduce an alternative mechanism based on the coexistence of two homogeneous stable states and spatial coupling. We show the existence of a threshold for perturbations of the homogeneous state. Subthreshold perturbations decay exponentially. Superthreshold perturbations induce the emergence of a long-lived structure formed by two back to back fronts that join the two homogeneous states. While in typical excitability the trajectory follows the remnants of a limit cycle, here reinjection is provided by front interaction, such that fronts slowly approach each other until eventually annihilating. This front-mediated mechanism shows that extended systems with no oscillatory regimes can display excitability.

  13. Energy conversion at dipolarization fronts

    NASA Astrophysics Data System (ADS)

    Khotyaintsev, Yu. V.; Divin, A.; Vaivads, A.; André, M.; Markidis, S.

    2017-02-01

    We use multispacecraft observations by Cluster in the Earth's magnetotail and 3-D particle-in-cell simulations to investigate conversion of electromagnetic energy at the front of a fast plasma jet. We find that the major energy conversion is happening in the Earth (laboratory) frame, where the electromagnetic energy is being transferred from the electromagnetic field to particles. This process operates in a region with size of the order several ion inertial lengths across the jet front, and the primary contribution to E·j is coming from the motional electric field and the ion current. In the frame of the front we find fluctuating energy conversion with localized loads and generators at sub-ion scales which are primarily related to the lower hybrid drift instability excited at the front; however, these provide relatively small net energy conversion.

  14. QCD and Light-Front Holography

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.; /Costa Rica U.

    2010-10-27

    The soft-wall AdS/QCD model, modified by a positive-sign dilaton metric, leads to a remarkable one-parameter description of nonperturbative hadron dynamics. The model predicts a zero-mass pion for zero-mass quarks and a Regge spectrum of linear trajectories with the same slope in the leading orbital angular momentum L of hadrons and the radial quantum number N. Light-Front Holography maps the amplitudes which are functions of the fifth dimension variable z of anti-de Sitter space to a corresponding hadron theory quantized on the light front. The resulting Lorentz-invariant relativistic light-front wave equations are functions of an invariant impact variable {zeta} which measures the separation of the quark and gluonic constituents within the hadron at equal light-front time. The result is to a semi-classical frame-independent first approximation to the spectra and light-front wavefunctions of meson and baryon light-quark bound states, which in turn predict the behavior of the pion and nucleon form factors. The theory implements chiral symmetry in a novel way: the effects of chiral symmetry breaking increase as one goes toward large interquark separation, consistent with spectroscopic data, and the the hadron eigenstates generally have components with different orbital angular momentum; e.g., the proton eigenstate in AdS/QCD with massless quarks has L = 0 and L = 1 light-front Fock components with equal probability. The soft-wall model also predicts the form of the non-perturbative effective coupling {alpha}{sub s}{sup AdS} (Q) and its {beta}-function which agrees with the effective coupling {alpha}{sub g1} extracted from the Bjorken sum rule. The AdS/QCD model can be systematically improved by using its complete orthonormal solutions to diagonalize the full QCD light-front Hamiltonian or by applying the Lippmann-Schwinger method in order to systematically include the QCD interaction terms. A new perspective on quark and gluon condensates is also reviewed.

  15. Radiative magnetized thermal conduction fronts

    NASA Technical Reports Server (NTRS)

    Borkowski, Kazimierz J.; Balbus, Steven A.; Fristrom, Carl C.

    1990-01-01

    The evolution of plane-parallel magnetized thermal conduction fronts in the interstellar medium (ISM) was studied. Separating the coronal ISM phase and interstellar clouds, these fronts have been thought to be the site of the intermediate-temperature regions whose presence was inferred from O VI absorption-line studies. The front evolution was followed numerically, starting from the initial discontinuous temperature distribution between the hot and cold medium, and ending in the final cooling stage of the hot medium. It was found that, for the typical ISM pressure of 4000 K/cu cm and the hot medium temperature of 10 to the 6th K, the transition from evaporation to condensation in a nonmagnetized front occurs when the front thickness is 15 pc. This thickness is a factor of 5 smaller than previously estimated. The O VI column densities in both evaporative and condensation stages agree with observations if the initial hot medium temperature Th exceeds 750,000 K. Condensing conduction fronts give better agreement with observed O VI line profiles because of lower gas temperatures.

  16. Advanced Fabrication Method for the Preparation of MOF Thin Films: Liquid-Phase Epitaxy Approach Meets Spin Coating Method.

    PubMed

    Chernikova, Valeriya; Shekhah, Osama; Eddaoudi, Mohamed

    2016-08-10

    Here, we report a new and advanced method for the fabrication of highly oriented/polycrystalline metal-organic framework (MOF) thin films. Building on the attractive features of the liquid-phase epitaxy (LPE) approach, a facile spin coating method was implemented to generate MOF thin films in a high-throughput fashion. Advantageously, this approach offers a great prospective to cost-effectively construct thin-films with a significantly shortened preparation time and a lessened chemicals and solvents consumption, as compared to the conventional LPE-process. Certainly, this new spin-coating approach has been implemented successfully to construct various MOF thin films, ranging in thickness from a few micrometers down to the nanometer scale, spanning 2-D and 3-D benchmark MOF materials including Cu2(bdc)2·xH2O, Zn2(bdc)2·xH2O, HKUST-1, and ZIF-8. This method was appraised and proved effective on a variety of substrates comprising functionalized gold, silicon, glass, porous stainless steel, and aluminum oxide. The facile, high-throughput and cost-effective nature of this approach, coupled with the successful thin film growth and substrate versatility, represents the next generation of methods for MOF thin film fabrication. Therefore, paving the way for these unique MOF materials to address a wide range of challenges in the areas of sensing devices and membrane technology.

  17. Recent advances in nanoparticle preparation by spray and micro-emulsion methods.

    PubMed

    Eslamian, Morteza; Shekarriz, Marzieh

    2009-01-01

    Micro- and nano-sized metal, semiconductor, pharmaceutical, and simple or complex ceramic particles have numerous applications in the development of sensors, thermal barrier coatings, catalysts, pigments, drugs, etc. The challenges include controlling the particle size, size distribution, particle crystallinity, morphology and shape, being able to use the nanoparticles for a given purpose, and to produce them from a variety of precursors. There are several methods to produce nanoparticles, each suitable for a range of applications. In this article, two methods that are receiving increasing attention are considered: spray and microemulsion methods. Spray techniques are single-step methods of producing a broad spectrum of simple to multicomponent functional micro and nanoparticles and quantum dots. Microemulsion is a wet chemistry method. A micro-emulsion system consists of aqueous domains, called reverse micelles, dispersed in a continuous oil phase. In this article, the above mentioned methods of nanoparticle production are introduced and recent advances, research directions and challenges, and the pertinent patents are reviewed and discussed.

  18. Advanced methods comparisons of reaction rates in the Purdue Fast Breeder Blanket Facility

    SciTech Connect

    Hill, R.N.; Ott, K.O.

    1988-01-01

    A review of worldwide results revealed that reaction rates in the blanket region are generally underpredicted with the discrepancy increasing with penetration; however, these results vary widely. Experiments in the large uniform Purdue Fast Breeder Blanket Facility (FBBF) blanket yield an accurate quantification of this discrepancy. Using standard production code methods (diffusion theory with 50 group cross sections), a consistent Calculated/Experimental (C/E) drop-off was observed for various reaction rates. A 50% increase in the calculated results at the outer edge of the blanket is necessary for agreement with experiments. The usefulness of refined group constant generation utilizing specialized weighting spectra and transport theory methods in correcting this discrepancy was analyzed. Refined group constants reduce the discrepancy to half that observed using the standard method. The surprising result was that transport methods had no effect on the blanket deviations; thus, transport theory considerations do not constitute or even contribute to an explanation of the blanket discrepancies. The residual blanket C/E drop-off (about half the standard drop-off) using advanced methods must be caused by some approximations which are applied in all current methods. 27 refs., 3 figs., 1 tab.

  19. Advanced display object selection methods for enhancing user-computer productivity

    NASA Technical Reports Server (NTRS)

    Osga, Glenn A.

    1993-01-01

    The User-Interface Technology Branch at NCCOSC RDT&E Division has been conducting a series of studies to address the suitability of commercial off-the-shelf (COTS) graphic user-interface (GUI) methods for efficiency and performance in critical naval combat systems. This paper presents an advanced selection algorithm and method developed to increase user performance when making selections on tactical displays. The method has also been applied with considerable success to a variety of cursor and pointing tasks. Typical GUI's allow user selection by: (1) moving a cursor with a pointing device such as a mouse, trackball, joystick, touchscreen; and (2) placing the cursor on the object. Examples of GUI objects are the buttons, icons, folders, scroll bars, etc. used in many personal computer and workstation applications. This paper presents an improved method of selection and the theoretical basis for the significant performance gains achieved with various input devices tested. The method is applicable to all GUI styles and display sizes, and is particularly useful for selections on small screens such as notebook computers. Considering the amount of work-hours spent pointing and clicking across all styles of available graphic user-interfaces, the cost/benefit in applying this method to graphic user-interfaces is substantial, with the potential for increasing productivity across thousands of users and applications.

  20. PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data

    PubMed Central

    2013-01-01

    Background Tandem affinity purification coupled with mass-spectrometry (TAP/MS) analysis is a popular method for the identification of novel endogenous protein-protein interactions (PPIs) in large-scale. Computational analysis of TAP/MS data is a critical step, particularly for high-throughput datasets, yet it remains challenging due to the noisy nature of TAP/MS data. Results We investigated several major TAP/MS data analysis methods for identifying PPIs, and developed an advanced method, which incorporates an improved statistical method to filter out false positives from the negative controls. Our method is named PPIRank that stands for PPI ranking in TAP/MS data. We compared PPIRank with several other existing methods in analyzing two pathway-specific TAP/MS PPI datasets from Drosophila. Conclusion Experimental results show that PPIRank is more capable than other approaches in terms of identifying known interactions collected in the BioGRID PPI database. Specifically, PPIRank is able to capture more true interactions and simultaneously less false positives in both Insulin and Hippo pathways of Drosophila Melanogaster. PMID:24565074

  1. Methods and advances in metabolic flux analysis: a mini-review.

    PubMed

    Antoniewicz, Maciek R

    2015-03-01

    Metabolic flux analysis (MFA) is one of the pillars of metabolic engineering. Over the past three decades, it has been widely used to quantify intracellular metabolic fluxes in both native (wild type) and engineered biological systems. Through MFA, changes in metabolic pathway fluxes are quantified that result from genetic and/or environmental interventions. This information, in turn, provides insights into the regulation of metabolic pathways and may suggest new targets for further metabolic engineering of the strains. In this mini-review, we discuss and classify the various methods of MFA that have been developed, which include stoichiometric MFA, (13)C metabolic flux analysis, isotopic non-stationary (13)C metabolic flux analysis, dynamic metabolic flux analysis, and (13)C dynamic metabolic flux analysis. For each method, we discuss key advantages and limitations and conclude by highlighting important recent advances in flux analysis approaches.

  2. Methods for Quantification of Soil-Transmitted Helminths in Environmental Media: Current Techniques and Recent Advances.

    PubMed

    Collender, Philip A; Kirby, Amy E; Addiss, David G; Freeman, Matthew C; Remais, Justin V

    2015-12-01

    Limiting the environmental transmission of soil-transmitted helminths (STHs), which infect 1.5 billion people worldwide, will require sensitive, reliable, and cost-effective methods to detect and quantify STHs in the environment. We review the state-of-the-art of STH quantification in soil, biosolids, water, produce, and vegetation with regard to four major methodological issues: environmental sampling; recovery of STHs from environmental matrices; quantification of recovered STHs; and viability assessment of STH ova. We conclude that methods for sampling and recovering STHs require substantial advances to provide reliable measurements for STH control. Recent innovations in the use of automated image identification and developments in molecular genetic assays offer considerable promise for improving quantification and viability assessment.

  3. Advanced fluorescence microscopy methods for the real-time study of transcription and chromatin dynamics

    PubMed Central

    Annibale, Paolo; Gratton, Enrico

    2014-01-01

    In this contribution we provide an overview of the recent advances allowed by the use of fluorescence microscopy methods in the study of transcriptional processes and their interplay with the chromatin architecture in living cells. Although the use of fluorophores to label nucleic acids dates back at least to about half a century ago,1 two recent breakthroughs have effectively opened the way to use fluorescence routinely for specific and quantitative probing of chromatin organization and transcriptional activity in living cells: namely, the possibility of labeling first the chromatin loci and then the mRNA synthesized from a gene using fluorescent proteins. In this contribution we focus on methods that can probe rapid dynamic processes by analyzing fast fluorescence fluctuations. PMID:25764219

  4. A Review of Failure Analysis Methods for Advanced 3D Microelectronic Packages

    NASA Astrophysics Data System (ADS)

    Li, Yan; Srinath, Purushotham Kaushik Muthur; Goyal, Deepak

    2016-01-01

    Advanced three dimensional (3D) packaging is a key enabler in driving form factor reduction, performance benefits, and package cost reduction, especially in the fast paced mobility and ultraportable consumer electronics segments. The high level of functional integration and the complex package architecture pose a significant challenge for conventional fault isolation (FI) and failure analysis (FA) methods. Innovative FI/FA tools and techniques are required to tackle the technical and throughput challenges. In this paper, the applications of FI and FA techniques such as Electro Optic Terahertz Pulse Reflectometry, 3D x-ray computed tomography, lock-in thermography, and novel physical sample preparation methods to 3D packages with package on package and stacked die with through silicon via configurations are reviewed, along with the key FI and FA challenges.

  5. Advanced adaptive computational methods for Navier-Stokes simulations in rotorcraft aerodynamics

    NASA Technical Reports Server (NTRS)

    Stowers, S. T.; Bass, J. M.; Oden, J. T.

    1993-01-01

    A phase 2 research and development effort was conducted in area transonic, compressible, inviscid flows with an ultimate goal of numerically modeling complex flows inherent in advanced helicopter blade designs. The algorithms and methodologies therefore are classified as adaptive methods, which are error estimation techniques for approximating the local numerical error, and automatically refine or unrefine the mesh so as to deliver a given level of accuracy. The result is a scheme which attempts to produce the best possible results with the least number of grid points, degrees of freedom, and operations. These types of schemes automatically locate and resolve shocks, shear layers, and other flow details to an accuracy level specified by the user of the code. The phase 1 work involved a feasibility study of h-adaptive methods for steady viscous flows, with emphasis on accurate simulation of vortex initiation, migration, and interaction. Phase 2 effort focused on extending these algorithms and methodologies to a three-dimensional topology.

  6. Improvements in the application and reporting of advanced Bland-Altman methods of comparison.

    PubMed

    Olofsen, Erik; Dahan, Albert; Borsboom, Gerard; Drummond, Gordon

    2015-02-01

    Bland and Altman have developed a measure called "limits of agreement" to assess correspondence of two methods of clinical measurement. In many circumstances, comparisons are made using several paired measurements in each individual subject. If such measurements are considered as statistically independent pairs, rather than as sets of measurements from separate individuals, limits of agreement will be too narrow. In addition, the confidence intervals for these limits will also be too narrow. Suitable software to compute valid limits of agreement and their confidence intervals is not readily available. Therefore, we set out to provide a freely available implementation accompanied by a formal description of the more advanced Bland-Altman comparison methods. We validate the implementation using simulated data, and demonstrate the effects caused by failing to take the presence of multiple paired measurements per individual properly into account. We propose a standard format of reporting that would improve analysis and interpretation of comparison studies.

  7. A novel method for analyzing sequential eye movements reveals strategic influence on Raven's Advanced Progressive Matrices.

    PubMed

    Hayes, Taylor R; Petrov, Alexander A; Sederberg, Per B

    2011-09-16

    Eye movements are an important data source in vision science. However, the vast majority of eye movement studies ignore sequential information in the data and utilize only first-order statistics. Here, we present a novel application of a temporal-difference learning algorithm to construct a scanpath successor representation (SR; P. Dayan, 1993) that captures statistical regularities in temporally extended eye movement sequences. We demonstrate the effectiveness of the scanpath SR on eye movement data from participants solving items from Raven's Advanced Progressive Matrices Test. Analysis of the SRs revealed individual differences in scanning patterns captured by two principal components that predicted individual Raven scores much better than existing methods. These scanpath SR components were highly interpretable and provided new insight into the role of strategic processing on the Raven test. The success of the scanpath SR in terms of prediction and interpretability suggests that this method could prove useful in a much broader context.

  8. Advanced magnetic resonance imaging techniques in the preterm brain: methods and applications.

    PubMed

    Tao, Joshua D; Neil, Jeffrey J

    2014-01-01

    Brain development and brain injury in preterm infants are areas of active research. Magnetic resonance imaging (MRI), a non-invasive tool applicable to both animal models and human infants, provides a wealth of information on this process by bridging the gap between histology (available from animal studies) and developmental outcome (available from clinical studies). Moreover, MRI also offers information regarding diagnosis and prognosis in the clinical setting. Recent advances in MR methods - diffusion tensor imaging, volumetric segmentation, surface based analysis, functional MRI, and quantitative metrics - further increase the sophistication of information available regarding both brain structure and function. In this review, we discuss the basics of these newer methods as well as their application to the study of premature infants.

  9. Advanced experimental applications for x-ray transmission gratings spectroscopy using a novel grating fabrication method

    NASA Astrophysics Data System (ADS)

    Hurvitz, G.; Ehrlich, Y.; Strum, G.; Shpilman, Z.; Levy, I.; Fraenkel, M.

    2012-08-01

    A novel fabrication method for soft x-ray transmission grating and other optical elements is presented. The method uses focused-ion-beam technology to fabricate high-quality free standing grating bars on transmission electron microscopy grids. High quality transmission gratings are obtained with superb accuracy and versatility. Using these gratings and back-illuminated CCD camera, absolutely calibrated x-ray spectra can be acquired for soft x-ray source diagnostics in the 100-3000 eV spectral range. Double grating combinations of identical or different parameters are easily fabricated, allowing advanced one-shot application of transmission grating spectroscopy. These applications include spectroscopy with different spectral resolutions, bandwidths, dynamic ranges, and may serve for identification of high-order contribution, and spectral calibrations of various x-ray optical elements.

  10. Methods for quantification of soil-transmitted helminths in environmental media: current techniques and recent advances

    PubMed Central

    Collender, Philip A.; Kirby, Amy E.; Addiss, David G.; Freeman, Matthew C.; Remais, Justin V.

    2015-01-01

    Limiting the environmental transmission of soil-transmitted helminths (STH), which infect 1.5 billion people worldwide, will require sensitive, reliable, and cost effective methods to detect and quantify STH in the environment. We review the state of the art of STH quantification in soil, biosolids, water, produce, and vegetation with respect to four major methodological issues: environmental sampling; recovery of STH from environmental matrices; quantification of recovered STH; and viability assessment of STH ova. We conclude that methods for sampling and recovering STH require substantial advances to provide reliable measurements for STH control. Recent innovations in the use of automated image identification and developments in molecular genetic assays offer considerable promise for improving quantification and viability assessment. PMID:26440788

  11. Front Interactions in a Three-Component System

    NASA Astrophysics Data System (ADS)

    van Heijster, P.; Doelman, A.; Kaper, T. J.; Promislow, K.

    2010-01-01

    The three-component reaction-diffusion system introduced in [C. P. Schenk et al., Phys. Rev. Lett., 78 (1997), pp. 3781] has become a paradigm model in pattern formation. It exhibits a rich variety of dynamics of fronts, pulses, and spots. The front and pulse interactions range in type from weak, in which the localized structures interact only through their exponentially small tails, to strong interactions, in which they annihilate or collide and in which all components are far from equilibrium in the domains between the localized structures. Intermediate to these two extremes sits the semistrong interaction regime, in which the activator component of the front is near equilibrium in the intervals between adjacent fronts but both inhibitor components are far from equilibrium there, and hence their concentration profiles drive the front evolution. In this paper, we focus on dynamically evolving N-front solutions in the semistrong regime. The primary result is use of a renormalization group method to rigorously derive the system of N coupled ODEs that governs the positions of the fronts. The operators associated with the linearization about the N-front solutions have N small eigenvalues, and the N-front solutions may be decomposed into a component in the space spanned by the associated eigenfunctions and a component projected onto the complement of this space. This decomposition is carried out iteratively at a sequence of times. The former projections yield the ODEs for the front positions, while the latter projections are associated with remainders that we show stay small in a suitable norm during each iteration of the renormalization group method. Our results also help extend the application of the renormalization group method from the weak interaction regime for which it was initially developed to the semistrong interaction regime. The second set of results that we present is a detailed analysis of this system of ODEs, providing a classification of the possible

  12. Setting health research priorities using the CHNRI method: IV. Key conceptual advances

    PubMed Central

    Rudan, Igor

    2016-01-01

    Introduction Child Health and Nutrition Research Initiative (CHNRI) started as an initiative of the Global Forum for Health Research in Geneva, Switzerland. Its aim was to develop a method that could assist priority setting in health research investments. The first version of the CHNRI method was published in 2007–2008. The aim of this paper was to summarize the history of the development of the CHNRI method and its key conceptual advances. Methods The guiding principle of the CHNRI method is to expose the potential of many competing health research ideas to reduce disease burden and inequities that exist in the population in a feasible and cost–effective way. Results The CHNRI method introduced three key conceptual advances that led to its increased popularity in comparison to other priority–setting methods and processes. First, it proposed a systematic approach to listing a large number of possible research ideas, using the “4D” framework (description, delivery, development and discovery research) and a well–defined “depth” of proposed research ideas (research instruments, avenues, options and questions). Second, it proposed a systematic approach for discriminating between many proposed research ideas based on a well–defined context and criteria. The five “standard” components of the context are the population of interest, the disease burden of interest, geographic limits, time scale and the preferred style of investing with respect to risk. The five “standard” criteria proposed for prioritization between research ideas are answerability, effectiveness, deliverability, maximum potential for disease burden reduction and the effect on equity. However, both the context and the criteria can be flexibly changed to meet the specific needs of each priority–setting exercise. Third, it facilitated consensus development through measuring collective optimism on each component of each research idea among a larger group of experts using a simple

  13. Advanced Methods for Aircraft Engine Thrust and Noise Benefits: Nozzle-Inlet Flow Analysis

    NASA Technical Reports Server (NTRS)

    Morgan, Morris H., III; Gilinsky, Mikhail M.

    2004-01-01

    In this project on the first stage (2000-Ol), we continued to develop the previous joint research between the Fluid Mechanics and Acoustics Laboratory (FM&AL) at Hampton University (HU) and the Jet Noise Team (JNT) at the NASA Langley Research Center (NASA LaRC). At the second stage (2001-03), FM&AL team concentrated its efforts on solving of problems of interest to Glenn Research Center (NASA GRC), especially in the field of propulsion system enhancement. The NASA GRC R&D Directorate and LaRC Hyper-X Program specialists in a hypersonic technology jointly with the FM&AL staff conducted research on a wide region of problems in the propulsion field as well as in experimental testing and theoretical and numerical simulation analyses for advanced aircraft and rocket engines. The last year the Hampton University School of Engineering & Technology was awarded the NASA grant, for creation of the Aeropropulsion Center, and the FM&AL is a key team of the project fulfillment responsible for research in Aeropropulsion and Acoustics (Pillar I). This work is supported by joint research between the NASA GRC/ FM&AL and the Institute of Mechanics at Moscow State University (IMMSU) in Russia under a CRDF grant. The main areas of current scientific interest of the FM&AL include an investigation of the proposed and patented advanced methods for aircraft engine thrust and noise benefits. This is the main subject of our other projects, of which one is presented. The last year we concentrated our efforts to analyze three main problems: (a) new effective methods fuel injection into the flow stream in air-breathing engines; (b) new re-circulation method for mixing, heat transfer and combustion enhancement in propulsion systems and domestic industry application; (c) covexity flow The research is focused on a wide regime of problems in the propulsion field as well as in experimental testing and theoretical and numerical simulation analyses for advanced aircraft and rocket engines (see, for

  14. Verification of a Depletion Method in SCALE for the Advanced High Temperature Reactor

    SciTech Connect

    KELLY, RYAN; Ilas, Dan

    2013-01-01

    This study describes a new approach employing the Dancoff correction method to model the TRISO-based fuel form used by the Advanced High-Temperature Reactor (AHTR) reactor design concept. The Dancoff correction method is used to perform isotope depletion analysis using the TRITON sequence of SCALE and is verified by code-to-code comparisons. The current AHTR fuel design has TRISO particles concentrated along the edges of a slab fuel element. This geometry prevented the use of the DOUBLEHET treatment, previously developed in SCALE to model spherical and cylindrical fuel. The new method permits fuel depletion on complicated geometries that traditionally can be handled only by continuous energy based depletion code systems. The method was initially tested on a fuel configuration typical of the Next Generation Nuclear Plant (NGNP), where DOUBLEHET treatment is possible. A confirmatory study was performed on the AHTR reference core geometry using the VESTA code, which uses the continuous energy MCNP5 code as a transport solver and ORIGEN2.2 code for depletion calculations. Comparisons of the results indicate good agreement of whole core characteristics, such as the multiplication factor and the isotopics, including their spatial distribution. Key isotopes analyzed included 235U, 239Pu, 240Pu, and 241Pu. The results from this study indicate that the Dancoff factor method can generate estimates of core characteristics with reasonable precision for scoping studies of configurations where DOUBLEHET treatment cannot be performed.

  15. Aquatic ecosystem protection and restoration: Advances in methods for assessment and evaluation

    USGS Publications Warehouse

    Bain, M.B.; Harig, A.L.; Loucks, D.P.; Goforth, R.R.; Mills, K.E.

    2000-01-01

    Many methods and criteria are available to assess aquatic ecosystems, and this review focuses on a set that demonstrates advancements from community analyses to methods spanning large spatial and temporal scales. Basic methods have been extended by incorporating taxa sensitivity to different forms of stress, adding measures linked to system function, synthesizing multiple faunal groups, integrating biological and physical attributes, spanning large spatial scales, and enabling simulations through time. These tools can be customized to meet the needs of a particular assessment and ecosystem. Two case studies are presented to show how new methods were applied at the ecosystem scale for achieving practical management goals. One case used an assessment of biotic structure to demonstrate how enhanced river flows can improve habitat conditions and restore a diverse fish fauna reflective of a healthy riverine ecosystem. In the second case, multitaxonomic integrity indicators were successful in distinguishing lake ecosystems that were disturbed, healthy, and in the process of restoration. Most methods strive to address the concept of biological integrity and assessment effectiveness often can be impeded by the lack of more specific ecosystem management objectives. Scientific and policy explorations are needed to define new ways for designating a healthy system so as to allow specification of precise quality criteria that will promote further development of ecosystem analysis tools.

  16. A comparison report of three advanced methods for drug-cyclodextrin interaction measurements.

    PubMed

    Singh, Vikramjeet; He, Yaping; Wang, Caifen; Xu, Jianghui; Xu, Xiaonan; Li, Haiyan; Singh, Parbeen; York, Peter; Sun, Lixin; Zhang, Jiwen

    2017-02-05

    Three advanced methods, high performance affinity chromatography (HPAC), surface plasmon resonance (SPR) and surface plasmon resonance imaging (SPRi) were compared and evaluated for determining the drug-cyclodextrin (CD) interactions herein. In total, 18 sparingly soluble drugs were selected for this comparative study. The three methods share a unique connection in the working principles and strategies. The same strategies of CD fixation onto solid phase were used in HPAC and SPR for the measurements, whereas, the SPR and SPRi share identical working principles. However, whilst these relationships are evident, no strong correlation was found between kinetic constants obtained from the three methods: Four drugs, namely, prednisolone, pseudolaric acid B, diazepam and gramisetron failed to show any response on SPR, whereas, the kinetics parameters from SPRi and HPAC were successfully measured. From a comparative review of all the kinetic data, random results without any trends were observed (ka, kd and KA) regardless of the relationships between the three methods: It is apparent that the measurement conditions (volume, flow rate, buffers), non-specific adsorption and experimental procedures had a strong impact on the generated data. The relative advantages and limitations of each method are critically presented on the basis of generated data. This comparative study provides a basis to further upgrade these techniques for confident measurement of drug-CDs interactions.

  17. BELFA: an integrated bridge loading truck for application of the advanced test method EXTRA

    NASA Astrophysics Data System (ADS)

    Schwesinger, Peter; Thor, Bianca

    2001-08-01

    In Germany a research group from four universities has developed an advanced experimental supported objective condition assessment method for concrete bridges, called 'EXTRA'. This method is useable preferably in cases, where conventional assessment methods cannot be applied successfully. In the past more than 200 bridges and buildings were evaluated regarding their real actual load bearing capacity using this method. An authorized guideline for the practical use at concrete structures is available. Until now the process of mounting and dismantling the loading structure was the most time-consuming part of such a test and influenced testing costs and duration of traffic interruption decisive. This background and the technical conception for development and testing the truck prototype with a maximum total loading capacity of 150 t will be introduced. Main subjects are a brief characterization of EXTRA method, the truck structure, the hydraulic loading system, measurement equipment and control facilities as well as the loading regime and belonging on-line information controlling the structure response as main parts of the testing process. The concept of the future employment of such trucks and ideas for a co-operation of consulting offices, owners and authorities will be short discussed. First testing experiences and an outlook on further activities will be given. Acknowledgments finalize the contribution.

  18. A Combined Method for Segmentation and Registration for an Advanced and Progressive Evaluation of Thermal Images

    PubMed Central

    Barcelos, Emilio Z.; Caminhas, Walmir M.; Ribeiro, Eraldo; Pimenta, Eduardo M.; Palhares, Reinaldo M.

    2014-01-01

    In this paper, a method that combines image analysis techniques, such as segmentation and registration, is proposed for an advanced and progressive evaluation of thermograms. The method is applied for the prevention of muscle injury in high-performance athletes, in collaboration with a Brazilian professional soccer club. The goal is to produce information on spatio-temporal variations of thermograms favoring the investigation of the athletes' conditions along the competition. The proposed method improves on current practice by providing a means for automatically detecting adaptive body-shaped regions of interest, instead of the manual selection of simple shapes. Specifically, our approach combines the optimization features in Otsu's method with a correction factor and post-processing techniques, enhancing thermal-image segmentation when compared to other methods. Additional contributions resulting from the combination of the segmentation and registration steps of our approach are the progressive analyses of thermograms in a unique spatial coordinate system and the accurate extraction of measurements and isotherms. PMID:25414972

  19. Numerical Evaluation of Fluid Mixing Phenomena in Boiling Water Reactor Using Advanced Interface Tracking Method

    NASA Astrophysics Data System (ADS)

    Yoshida, Hiroyuki; Takase, Kazuyuki

    Thermal-hydraulic design of the current boiling water reactor (BWR) is performed with the subchannel analysis codes which incorporated the correlations based on empirical results including actual-size tests. Then, for the Innovative Water Reactor for Flexible Fuel Cycle (FLWR) core, an actual size test of an embodiment of its design is required to confirm or modify such correlations. In this situation, development of a method that enables the thermal-hydraulic design of nuclear reactors without these actual size tests is desired, because these tests take a long time and entail great cost. For this reason, we developed an advanced thermal-hydraulic design method for FLWRs using innovative two-phase flow simulation technology. In this study, a detailed Two-Phase Flow simulation code using advanced Interface Tracking method: TPFIT is developed to calculate the detailed information of the two-phase flow. In this paper, firstly, we tried to verify the TPFIT code by comparing it with the existing 2-channel air-water mixing experimental results. Secondary, the TPFIT code was applied to simulation of steam-water two-phase flow in a model of two subchannels of a current BWRs and FLWRs rod bundle. The fluid mixing was observed at a gap between the subchannels. The existing two-phase flow correlation for fluid mixing is evaluated using detailed numerical simulation data. This data indicates that pressure difference between fluid channels is responsible for the fluid mixing, and thus the effects of the time average pressure difference and fluctuations must be incorporated in the two-phase flow correlation for fluid mixing. When inlet quality ratio of subchannels is relatively large, it is understood that evaluation precision of the existing two-phase flow correlations for fluid mixing are relatively low.

  20. Accuracy Evaluation of a Mobile Mapping System with Advanced Statistical Methods

    NASA Astrophysics Data System (ADS)

    Toschi, I.; Rodríguez-Gonzálvez, P.; Remondino, F.; Minto, S.; Orlandini, S.; Fuller, A.

    2015-02-01

    This paper discusses a methodology to evaluate the precision and the accuracy of a commercial Mobile Mapping System (MMS) with advanced statistical methods. So far, the metric potentialities of this emerging mapping technology have been studied in few papers, where generally the assumption that errors follow a normal distribution is made. In fact, this hypothesis should be carefully verified in advance, in order to test how well the Gaussian classic statistics can adapt to datasets that are usually affected by asymmetrical gross errors. The workflow adopted in this study relies on a Gaussian assessment, followed by an outlier filtering process. Finally, non-parametric statistical models are applied, in order to achieve a robust estimation of the error dispersion. Among the different MMSs available on the market, the latest solution provided by RIEGL is here tested, i.e. the VMX-450 Mobile Laser Scanning System. The test-area is the historic city centre of Trento (Italy), selected in order to assess the system performance in dealing with a challenging and historic urban scenario. Reference measures are derived from photogrammetric and Terrestrial Laser Scanning (TLS) surveys. All datasets show a large lack of symmetry that leads to the conclusion that the standard normal parameters are not adequate to assess this type of data. The use of non-normal statistics gives thus a more appropriate description of the data and yields results that meet the quoted a-priori errors.

  1. Evaluation of Advanced Stirling Convertor Net Heat Input Correlation Methods Using a Thermal Standard

    NASA Technical Reports Server (NTRS)

    Briggs, Maxwell H.; Schifer, Nicholas A.

    2012-01-01

    The U.S. Department of Energy (DOE) and Lockheed Martin Space Systems Company (LMSSC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. This generator would use two high-efficiency Advanced Stirling Convertors (ASCs), developed by Sunpower Inc. and NASA Glenn Research Center (GRC). The ASCs convert thermal energy from a radioisotope heat source into electricity. As part of ground testing of these ASCs, different operating conditions are used to simulate expected mission conditions. These conditions require achieving a particular operating frequency, hot end and cold end temperatures, and specified electrical power output for a given net heat input. In an effort to improve net heat input predictions, numerous tasks have been performed which provided a more accurate value for net heat input into the ASCs, including testing validation hardware, known as the Thermal Standard, to provide a direct comparison to numerical and empirical models used to predict convertor net heat input. This validation hardware provided a comparison for scrutinizing and improving empirical correlations and numerical models of ASC-E2 net heat input. This hardware simulated the characteristics of an ASC-E2 convertor in both an operating and non-operating mode. This paper describes the Thermal Standard testing and the conclusions of the validation effort applied to the empirical correlation methods used by the Radioisotope Power System (RPS) team at NASA Glenn.

  2. Projected role of advanced computational aerodynamic methods at the Lockheed-Georgia company

    NASA Technical Reports Server (NTRS)

    Lores, M. E.

    1978-01-01

    Experience with advanced computational methods being used at the Lockheed-Georgia Company to aid in the evaluation and design of new and modified aircraft indicates that large and specialized computers will be needed to make advanced three-dimensional viscous aerodynamic computations practical. The Numerical Aerodynamic Simulation Facility should be used to provide a tool for designing better aerospace vehicles while at the same time reducing development costs by performing computations using Navier-Stokes equations solution algorithms and permitting less sophisticated but nevertheless complex calculations to be made efficiently. Configuration definition procedures and data output formats can probably best be defined in cooperation with industry, therefore, the computer should handle many remote terminals efficiently. The capability of transferring data to and from other computers needs to be provided. Because of the significant amount of input and output associated with 3-D viscous flow calculations and because of the exceedingly fast computation speed envisioned for the computer, special attention should be paid to providing rapid, diversified, and efficient input and output.

  3. Applications of flight control system methods to an advanced combat rotorcraft

    NASA Technical Reports Server (NTRS)

    Tischler, Mark B.; Fletcher, Jay W.; Morris, Patrick M.; Tucker, George T.

    1989-01-01

    Advanced flight control system design, analysis, and testing methodologies developed at the Ames Research Center are applied in an analytical and flight test evaluation of the Advanced Digital Optical Control System (ADOCS) demonstrator. The primary objectives are to describe the knowledge gained about the implications of digital flight control system design for rotorcraft, and to illustrate the analysis of the resulting handling-qualities in the context of the proposed new handling-qualities specification for rotorcraft. Topics covered in-depth are digital flight control design and analysis methods, flight testing techniques, ADOCS handling-qualities evaluation results, and correlation of flight test results with analytical models and the proposed handling-qualities specification. The evaluation of the ADOCS demonstrator indicates desirable response characteristics based on equivalent damping and frequency, but undersirably large effective time-delays (exceeding 240 m sec in all axes). Piloted handling-qualities are found to be desirable or adequate for all low, medium, and high pilot gain tasks; but handling-qualities are inadequate for ultra-high gain tasks such as slope and running landings.

  4. Chaos of radiative heat-loss-induced flame front instability.

    PubMed

    Kinugawa, Hikaru; Ueda, Kazuhiro; Gotoda, Hiroshi

    2016-03-01

    We are intensively studying the chaos via the period-doubling bifurcation cascade in radiative heat-loss-induced flame front instability by analytical methods based on dynamical systems theory and complex networks. Significant changes in flame front dynamics in the chaotic region, which cannot be seen in the bifurcation diagrams, were successfully extracted from recurrence quantification analysis and nonlinear forecasting and from the network entropy. The temporal dynamics of the fuel concentration in the well-developed chaotic region is much more complicated than that of the flame front temperature. It exhibits self-affinity as a result of the scale-free structure in the constructed visibility graph.

  5. On the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods

    PubMed Central

    Lee, Anthony; Yau, Christopher; Giles, Michael B.; Doucet, Arnaud; Holmes, Christopher C.

    2011-01-01

    We present a case-study on the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods. Graphics cards, containing multiple Graphics Processing Units (GPUs), are self-contained parallel computational devices that can be housed in conventional desktop and laptop computers and can be thought of as prototypes of the next generation of many-core processors. For certain classes of population-based Monte Carlo algorithms they offer massively parallel simulation, with the added advantage over conventional distributed multi-core processors that they are cheap, easily accessible, easy to maintain, easy to code, dedicated local devices with low power consumption. On a canonical set of stochastic simulation examples including population-based Markov chain Monte Carlo methods and Sequential Monte Carlo methods, we nd speedups from 35 to 500 fold over conventional single-threaded computer code. Our findings suggest that GPUs have the potential to facilitate the growth of statistical modelling into complex data rich domains through the availability of cheap and accessible many-core computation. We believe the speedup we observe should motivate wider use of parallelizable simulation methods and greater methodological attention to their design. PMID:22003276

  6. On the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods.

    PubMed

    Lee, Anthony; Yau, Christopher; Giles, Michael B; Doucet, Arnaud; Holmes, Christopher C

    2010-12-01

    We present a case-study on the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods. Graphics cards, containing multiple Graphics Processing Units (GPUs), are self-contained parallel computational devices that can be housed in conventional desktop and laptop computers and can be thought of as prototypes of the next generation of many-core processors. For certain classes of population-based Monte Carlo algorithms they offer massively parallel simulation, with the added advantage over conventional distributed multi-core processors that they are cheap, easily accessible, easy to maintain, easy to code, dedicated local devices with low power consumption. On a canonical set of stochastic simulation examples including population-based Markov chain Monte Carlo methods and Sequential Monte Carlo methods, we nd speedups from 35 to 500 fold over conventional single-threaded computer code. Our findings suggest that GPUs have the potential to facilitate the growth of statistical modelling into complex data rich domains through the availability of cheap and accessible many-core computation. We believe the speedup we observe should motivate wider use of parallelizable simulation methods and greater methodological attention to their design.

  7. [Advances in development of gene-gene interaction analysis methods based on SNP data: a review].

    PubMed

    Luan, Yi-Zhao; Zuo, Xiao-Yu; Liu, Ke; Li, Gu; Rao, Shao-Qi

    2013-12-01

    The SNP-based association analysis has become one of the most important approaches to interpret the underlying molecular mechanisms for human complex diseases. Nevertheless, the widely-used singe-locus analysis is only capable of capturing a small portion of susceptible SNPs with prominent marginal effects, leaving the important genetic component, epistasis or joint effects, to be undetectable. Identifying the complex interplays among multiple genes in the genome-wide context is an essential task for systematically unraveling the molecular mechanisms for complex diseases. Many approaches have been used to detect genome-wide gene-gene interactions and provided new insights into the genetic basis of complex diseases. This paper reviewed recent advances of the methods for detecting gene-gene interaction, categorized into three types, model-based and model-free statistical methods, and data mining methods, based on their characteristics in theory and numerical algorithm. In particular, the basic principle, numerical implementation and cautions for application for each method were elucidated. In addition, this paper briefly discussed the limitations and challenges associated with detecting genome-wide epistasis, in order to provide some methodological consultancies for scientists in the related fields.

  8. Spatially hybrid computations for streamer discharges with generic features of pulled fronts: I. Planar fronts

    SciTech Connect

    Li Chao Ebert, Ute Hundsdorfer, Willem

    2010-01-01

    Streamers are the first stage of sparks and lightning; they grow due to a strongly enhanced electric field at their tips; this field is created by a thin curved space charge layer. These multiple scales are already challenging when the electrons are approximated by densities. However, electron density fluctuations in the leading edge of the front and non-thermal stretched tails of the electron energy distribution (as a cause of X-ray emissions) require a particle model to follow the electron motion. But present computers cannot deal with all electrons in a fully developed streamer. Therefore, super-particle have to be introduced, which leads to wrong statistics and numerical artifacts. The method of choice is a hybrid computation in space where individual electrons are followed in the region of high electric field and low density while the bulk of the electrons is approximated by densities (or fluids). We here develop the hybrid coupling for planar fronts. First, to obtain a consistent flux at the interface between particle and fluid model in the hybrid computation, the widely used classical fluid model is replaced by an extended fluid model. Then the coupling algorithm and the numerical implementation of the spatially hybrid model are presented in detail, in particular, the position of the model interface and the construction of the buffer region. The method carries generic features of pulled fronts that can be applied to similar problems like large deviations in the leading edge of population fronts, etc.

  9. Advanced Thermal Energy Conversion of Temperature under 300°C by Thermoelectric Conversion Method

    NASA Astrophysics Data System (ADS)

    Ueda, Tadashi; Uchida, Yoshiyuki; Shingu, Hiroyasu

    Many approaches have been developing for energy conversion throughout the world. However, it is difficult to achieve the global warming countermeasure based on “The Kyoto protocol”. Until now effective utilization of low temperature thermal energy (under 300°C) is not advancing one. For example, effective utilization method has not been established for waste heat energy which arise from industry machine tools, automobiles, internal combustion engines and thermal energy from natural environment, etc. In this paper, we reported the experiment for effective utilizing of low temperature (under 300°C) thermal energy conversion. The device used for the measurement is a copper thermo device. Thermo electromotive force of 150mW/cm2 was obtained at 200°C. The obtained thermo electromotive force is about 15 times higher in comparison with generally used alumal-chromal thermocouple. Our aim is that utilizes low temperature thermal energy effectively by converting into electricity.

  10. Characterization of organic and inorganic optoelectronic semiconductor devices using advanced spectroscopic methods

    NASA Astrophysics Data System (ADS)

    Schroeder, Raoul

    In this thesis, advanced spectroscopy methods are discussed and applied to gain understanding of the physical properties of organic conjugated molecules, II-VI thin film semiconductors, and vertical cavity surface emitting lasers (VCSEL). Experiments include single photon and two-photon excitation with lasers, with subsequent measurements of the absorption and photoluminescence, as well as photocurrent measurements using tungsten and xenon lamps, measuring the direct current and the alternating current of the devices. The materials are investigated in dissolved form (conjugated polymers), thin films (polymers, II-VI semiconductors), and complex layer structures (hybrid device, VCSEL). The experiments are analyzed and interpreted by newly developed or applied theories for two-photon saturation processes in semiconductors, bandgap shrinkage due to optically induced electron hole pairs, and the principle of detailed balance to describe the photoluminescence in thin film cadmium sulfide.

  11. Recent advances in statistical methods for the estimation of sediment and nutrient transport in rivers

    NASA Astrophysics Data System (ADS)

    Colin, T. A.

    1995-07-01

    This paper reviews advances in methods for estimating fluvial transport of suspended sediment and nutrients. Research from the past four years, mostly dealing with estimating monthly and annual loads, is emphasized. However, because this topic has not appeared in previous IUGG reports, some research prior to 1990 is included. The motivation for studying sediment transport has shifted during the past few decades. In addition to its role in filling reservoirs and channels, sediment is increasingly recognized as an important part of fluvial ecosystems and estuarine wetlands. Many groups want information about sediment transport [Bollman, 1992]: Scientists trying to understand benthic biology and catchment hydrology; citizens and policy-makers concerned about environmental impacts (e.g. impacts of logging [Beschta, 1978] or snow-fences [Sturges, 1992]); government regulators considering the effectiveness of programs to protect in-stream habitat and downstream waterbodies; and resource managers seeking to restore wetlands.

  12. On the Use of Accelerated Test Methods for Characterization of Advanced Composite Materials

    NASA Technical Reports Server (NTRS)

    Gates, Thomas S.

    2003-01-01

    A rational approach to the problem of accelerated testing for material characterization of advanced polymer matrix composites is discussed. The experimental and analytical methods provided should be viewed as a set of tools useful in the screening of material systems for long-term engineering properties in aerospace applications. Consideration is given to long-term exposure in extreme environments that include elevated temperature, reduced temperature, moisture, oxygen, and mechanical load. Analytical formulations useful for predictive models that are based on the principles of time-based superposition are presented. The need for reproducible mechanisms, indicator properties, and real-time data are outlined as well as the methodologies for determining specific aging mechanisms.

  13. Advances in sample preparation in electromigration, chromatographic and mass spectrometric separation methods.

    PubMed

    Gilar, M; Bouvier, E S; Compton, B J

    2001-02-16

    The quality of sample preparation is a key factor in determining the success of analysis. While analysis of pharmaceutically important compounds in biological matrixes has driven forward the development of sample clean-up procedures in last 20 years, today's chemists face an additional challenge: sample preparation and analysis of complex biochemical samples for characterization of genotypic or phenotypic information contained in DNA and proteins. This review focuses on various sample pretreatment methods designed to meet the requirements for the analysis of biopolymers and small drugs in complex matrices. We discuss the advances in development of solid-phase extraction (SPE) sorbents, on-line SPE, membrane-based sample preparation, and sample clean-up of biopolymers prior to their analysis by mass spectrometry.

  14. ADVANCED MR IMAGING METHODS FOR PLANNING AND MONITORING RADIATION THERAPY IN PATIENTS WITH HIGH GRADE GLIOMA

    PubMed Central

    Lupo, Janine M.; Nelson, Sarah J.

    2016-01-01

    This review explores how the integration of advanced imaging methods with high quality anatomic images significantly improves the characterization, target definition, assessment of response to therapy, and overall management of patients with high-grade glioma. Metrics derived from diffusion, perfusion, and susceptibility weighted MR imaging in conjunction with MR spectroscopic imaging, allows us to characterize regions of edema, hypoxia, increased cellularity, and necrosis within heterogeneous tumor and surrounding brain tissue. Quantification of such measures may provide a more reliable initial representation of tumor delineation and response to therapy than changes in the contrast enhancing or T2 lesion alone and have a significant impact on targeting resection, planning radiation, and assessing treatment effectiveness. In the long-term, implementation of these imaging methodologies can also aid in the identification of recurrent tumor and its differentiation from treatment-related confounds and facilitate the detection of radiation-induced vascular injury in otherwise normal appearing brain tissue. PMID:25219809

  15. Advances in the Development and Validation of Test Methods in the United States

    PubMed Central

    Casey, Warren M.

    2016-01-01

    The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) provides validation support for US Federal agencies and the US Tox21 interagency consortium, an interagency collaboration that is using high throughput screening (HTS) and other advanced approaches to better understand and predict chemical hazards to humans and the environment. The use of HTS data from assays relevant to the estrogen receptor signaling data pathway is used as an example of how HTS data can be combined with computational modeling to meet the needs of US agencies. As brief summary of US efforts in the areas of biologics testing, acute toxicity, and skin sensitization will also be provided. PMID:26977254

  16. Functional description of APS beamline front ends

    SciTech Connect

    Kuzay, T.

    1993-02-01

    Traditional synchrotron sources were designed to produce bending magnet radiation and have proven to be an essential scientific tool. Currently, a new generation of synchrotron sources is being built that will be able to accommodate a large number of insertion device (ID) and high quality bending magnet (BM) sources. One example is the 7-GeV Advanced Photon Source (APS) now under construction at Argonne National Laboratory. The research and development effort at the APS is designed to fully develop the potential of this new generation of synchrotron sources. Of the 40 straight sections in the APS storage ring, 34 will be available for IDs. The remaining six sections are reserved for the storage ring hardware and diagnostics. Although the ring incorporates 80 BMs, only 40 of them can be used to extract radiation. The accelerator hardware shadows five of these 40 bending magnets, so the maximum number of BM sources on the lattice is 35. Generally, a photon beamline consists of four functional sections. The first section is the ID or the BM, which provides the radiation source. The second section, which is immediately outside the storage ring but inside a concrete shielding tunnel, is the front end, which is designed to control, define, and/or confine the x-ray beam. In the case of the APS, the front ends are designed to confine the photon beam. The third section, just outside the concrete shielding tunnel and on the experimental floor, is the first optics enclosure, which contains optics to filter and monochromatize the photon beam. The fourth section of a beamline consists of beam transports, additional optics, and experiment stations to do the scientific investigations. This document describes only the front ends of the APS beamlines.

  17. Assessment of Crack Detection in Cast Austenitic Piping Components Using Advanced Ultrasonic Methods.

    SciTech Connect

    Anderson, Michael T.; Crawford, Susan L.; Cumblidge, Stephen E.; Diaz, Aaron A.; Doctor, Steven R.

    2007-01-01

    Studies conducted at the Pacific N¬orthwest National Laboratory (PNNL) in Richland, Washington, have focused on developing and evaluating the reliability of nondestructive examination (NDE) approaches for inspecting coarse-grained, cast stainless steel reactor components. The objective of this work is to provide information to the United States Nuclear Regulatory Commission (NRC) on the utility, effec¬tiveness and limitations of ultrasonic testing (UT) inspection techniques as related to the in-service inspec¬tion of primary system piping components in pressurized water reactors (PWRs). Cast stainless steel pipe specimens were examined that contain thermal and mechanical fatigue cracks located close to the weld roots and have inside/outside surface geometrical conditions that simulate several PWR primary piping configurations. In addition, segments of vintage centrifugally cast piping were also examined to understand inherent acoustic noise and scattering due to grain structures and determine consistency of UT responses from different locations. The advanced UT methods were applied from the outside surface of these specimens using automated scanning devices and water coupling. The low-frequency ultrasonic method employed a zone-focused, multi-incident angle inspection protocol (operating at 250-450 kHz) coupled with a synthetic aperture focusing technique (SAFT) for improved signal-to-noise and advanced imaging capabilities. The phased array approach was implemented with a modified instrument operating at 500 kHz and composite volumetric images of the specimens were generated. Re¬sults from laboratory studies for assessing detection, localization and sizing effectiveness are discussed in this paper.

  18. Light-Front Holography and Novel Effects in QCD

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.

    2008-12-18

    The correspondence between theories in anti-de Sitter space and conformal field theories in physical space-time leads to an analytic, semiclassical model for strongly-coupled QCD. Light-front holography allows hadronic amplitudes in the AdS fifth dimension to be mapped to frame-independent light-front wavefunctions of hadrons in physical space-time, thus providing a relativistic description of hadrons at the amplitude level. We identify the AdS coordinate z with an invariant light-front coordinate {zeta} which separates the dynamics of quark and gluon binding from the kinematics of constituent spin and internal orbital angular momentum. The result is a single-variable light-front Schroedinger equation for QCD which determines the eigenspectrum and the light-front wavefunctions of hadrons for general spin and orbital angular momentum. The mapping of electromagnetic and gravitational form factors in AdS space to their corresponding expressions in light-front theory confirms this correspondence. Some novel features of QCD are discussed, including the consequences of confinement for quark and gluon condensates and the behavior of the QCD coupling in the infrared. The distinction between static structure functions such as the probability distributions computed from the square of the light-front wavefunctions versus dynamical structure functions which include the effects of rescattering is emphasized. A new method for computing the hadronization of quark and gluon jets at the amplitude level, an event amplitude generator, is outlined.

  19. A Method for Consensus Reaching in Product Kansei Evaluation Using Advanced Particle Swarm Optimization

    PubMed Central

    2017-01-01

    Consumers' opinions toward product design alternatives are often subjective and perceptual, which reflect their perception about a product and can be described using Kansei adjectives. Therefore, Kansei evaluation is often employed to determine consumers' preference. However, how to identify and improve the reliability of consumers' Kansei evaluation opinions toward design alternatives has an important role in adding additional insurance and reducing uncertainty to successful product design. To solve this problem, this study employs a consensus model to measure consistence among consumers' opinions, and an advanced particle swarm optimization (PSO) algorithm combined with Linearly Decreasing Inertia Weight (LDW) method is proposed for consensus reaching by minimizing adjustment of consumers' opinions. Furthermore, the process of the proposed method is presented and the details are illustrated using an example of electronic scooter design evaluation. The case study reveals that the proposed method is promising for reaching a consensus through searching optimal solutions by PSO and improving the reliability of consumers' evaluation opinions toward design alternatives according to Kansei indexes. PMID:28316619

  20. [Theory and Practice of the Constructive Jigsaw Method in Advancing Domain Knowledge and Skills in Parallel].

    PubMed

    Masukawa, Hiroyuki

    2016-01-01

    The Learning Sciences constitute a rapidly expanding discipline that focuses on the learning potential of humans. In this paper, I will discuss the particular learning mechanism involved in the concomitant advancement of domain knowledge and 21st century skills, as well as the Constructive Jigsaw Method of knowledge construction through collaboration-that is, collaborative problem solving. An especially important focus on knowledge construction separates routine experts from adaptive experts. While routine experts develop a core set of skills that they apply throughout their lives with increasing efficiency, adaptive experts are much more likely to change their core skills and continually expand the depth of their expertise. This restructuring of core ideas and skills may reduce their efficiency in the short run but make them more flexible in the long run. The Constructive Jigsaw Method employs a learning mechanism that encourages the development of adaptive experts. Under this method, students first study a piece of material in an expert group. One member from each of several expert groups then joins a new study group, a jigsaw group. The members of this new group then combine what they have learned, creating new knowledge and a deeper understanding of the concept through collaboration, communication, and innovation.

  1. Treatment of winery wastewater by electrochemical methods and advanced oxidation processes.

    PubMed

    Orescanin, Visnja; Kollar, Robert; Nad, Karlo; Mikelic, Ivanka Lovrencic; Gustek, Stefica Findri

    2013-01-01

    The aim of this research was development of new system for the treatment of highly polluted wastewater (COD = 10240 mg/L; SS = 2860 mg/L) originating from vine-making industry. The system consisted of the main treatment that included electrochemical methods (electro oxidation, electrocoagulation using stainless steel, iron and aluminum electrode sets) with simultaneous sonication and recirculation in strong electromagnetic field. Ozonation combined with UV irradiation in the presence of added hydrogen peroxide was applied for the post-treatment of the effluent. Following the combined treatment, the final removal efficiencies of the parameters color, turbidity, suspended solids and phosphates were over 99%, Fe, Cu and ammonia approximately 98%, while the removal of COD and sulfates was 77% and 62%, respectively. A new approach combining electrochemical methods with ultrasound in the strong electromagnetic field resulted in significantly better removal efficiencies for majority of the measured parameters compared to the biological methods, advanced oxidation processes or electrocoagulation. Reduction of the treatment time represents another advantage of this new approach.

  2. Weathering Patterns of Ignitable Liquids with the Advanced Distillation Curve Method.

    PubMed

    Bruno, Thomas J; Allen, Samuel

    2013-01-01

    One can take advantage of the striking similarity of ignitable liquid vaporization (or weathering) patterns and the separation observed during distillation to predict the composition of residual compounds in fire debris. This is done with the advanced distillation curve (ADC) metrology, which separates a complex fluid by distillation into fractions that are sampled, and for which thermodynamically consistent temperatures are measured at atmospheric pressure. The collected sample fractions can be analyzed by any method that is appropriate. Analytical methods we have applied include gas chromatography (with flame ionization, mass spectrometric and sulfur chemiluminescence detection), thin layer chromatography, FTIR, Karl Fischer coulombic titrimetry, refractometry, corrosivity analysis, neutron activation analysis and cold neutron prompt gamma activation analysis. We have applied this method on product streams such as finished fuels (gasoline, diesel fuels, aviation fuels, rocket propellants), crude oils (including a crude oil made from swine manure) and waste oils streams (used automotive and transformer oils). In this paper, we present results on a variety of ignitable liquids that are not commodity fuels, chosen from the Ignitable Liquids Reference Collection (ILRC). These measurements are assembled into a preliminary database. From this selection, we discuss the significance and forensic application of the temperature data grid and the composition explicit data channel of the ADC.

  3. Weathering Patterns of Ignitable Liquids with the Advanced Distillation Curve Method

    PubMed Central

    Bruno, Thomas J; Allen, Samuel

    2013-01-01

    One can take advantage of the striking similarity of ignitable liquid vaporization (or weathering) patterns and the separation observed during distillation to predict the composition of residual compounds in fire debris. This is done with the advanced distillation curve (ADC) metrology, which separates a complex fluid by distillation into fractions that are sampled, and for which thermodynamically consistent temperatures are measured at atmospheric pressure. The collected sample fractions can be analyzed by any method that is appropriate. Analytical methods we have applied include gas chromatography (with flame ionization, mass spectrometric and sulfur chemiluminescence detection), thin layer chromatography, FTIR, Karl Fischer coulombic titrimetry, refractometry, corrosivity analysis, neutron activation analysis and cold neutron prompt gamma activation analysis. We have applied this method on product streams such as finished fuels (gasoline, diesel fuels, aviation fuels, rocket propellants), crude oils (including a crude oil made from swine manure) and waste oils streams (used automotive and transformer oils). In this paper, we present results on a variety of ignitable liquids that are not commodity fuels, chosen from the Ignitable Liquids Reference Collection (ILRC). These measurements are assembled into a preliminary database. From this selection, we discuss the significance and forensic application of the temperature data grid and the composition explicit data channel of the ADC. PMID:26401423

  4. A Method for Consensus Reaching in Product Kansei Evaluation Using Advanced Particle Swarm Optimization.

    PubMed

    Yang, Yan-Pu

    2017-01-01

    Consumers' opinions toward product design alternatives are often subjective and perceptual, which reflect their perception about a product and can be described using Kansei adjectives. Therefore, Kansei evaluation is often employed to determine consumers' preference. However, how to identify and improve the reliability of consumers' Kansei evaluation opinions toward design alternatives has an important role in adding additional insurance and reducing uncertainty to successful product design. To solve this problem, this study employs a consensus model to measure consistence among consumers' opinions, and an advanced particle swarm optimization (PSO) algorithm combined with Linearly Decreasing Inertia Weight (LDW) method is proposed for consensus reaching by minimizing adjustment of consumers' opinions. Furthermore, the process of the proposed method is presented and the details are illustrated using an example of electronic scooter design evaluation. The case study reveals that the proposed method is promising for reaching a consensus through searching optimal solutions by PSO and improving the reliability of consumers' evaluation opinions toward design alternatives according to Kansei indexes.

  5. PREFACE: Advanced many-body and statistical methods in mesoscopic systems

    NASA Astrophysics Data System (ADS)

    Anghel, Dragos Victor; Sabin Delion, Doru; Sorin Paraoanu, Gheorghe

    2012-02-01

    It has increasingly been realized in recent times that the borders separating various subfields of physics are largely artificial. This is the case for nanoscale physics, physics of lower-dimensional systems and nuclear physics, where the advanced techniques of many-body theory developed in recent times could provide a unifying framework for these disciplines under the general name of mesoscopic physics. Other fields, such as quantum optics and quantum information, are increasingly using related methods. The 6-day conference 'Advanced many-body and statistical methods in mesoscopic systems' that took place in Constanta, Romania, between 27 June and 2 July 2011 was, we believe, a successful attempt at bridging an impressive list of topical research areas: foundations of quantum physics, equilibrium and non-equilibrium quantum statistics/fractional statistics, quantum transport, phases and phase transitions in mesoscopic systems/superfluidity and superconductivity, quantum electromechanical systems, quantum dissipation, dephasing, noise and decoherence, quantum information, spin systems and their dynamics, fundamental symmetries in mesoscopic systems, phase transitions, exactly solvable methods for mesoscopic systems, various extension of the random phase approximation, open quantum systems, clustering, decay and fission modes and systematic versus random behaviour of nuclear spectra. This event brought together participants from seventeen countries and five continents. Each of the participants brought considerable expertise in his/her field of research and, at the same time, was exposed to the newest results and methods coming from the other, seemingly remote, disciplines. The talks touched on subjects that are at the forefront of topical research areas and we hope that the resulting cross-fertilization of ideas will lead to new, interesting results from which everybody will benefit. We are grateful for the financial and organizational support from IFIN-HH, Ovidius

  6. Theory for the curvature dependence of delta front progradation

    NASA Astrophysics Data System (ADS)

    Ke, Wun-Tao; Capart, Hervé

    2015-12-01

    When Gilbert-type deltas respond to uneven sediment supply or advance over irregular basin bathymetry, they develop curved, creased fronts prograding at speeds that vary with location along the shoreline. Relations governing the progradation rate, however, have so far been proposed only for simple special cases. In this paper, we exploit the special properties of solutions to the eikonal equation to derive a general progradation relation, applicable to delta fronts of finite angle of repose and arbitrary shoreline planform. In these circumstances, the theory explicitly relates the progradation rate to the local shoreline curvature. We illustrate the resulting morphodynamics with numerical and analytical solutions for a sinuous delta front. The proposed relation can be used to model deltaic evolution or deduce spanwise distributions of sediment supply rates from observations of foreset evolution.

  7. Front Matter and Contents.

    PubMed

    2016-01-01

    ATCG model described in [1] ('Applied Theory accounting for human moleCular Genetics'), which constitutes a solid foundation for the present work. The author has a master degree in biochemistry, a master degree in computer science (systems development, informatics) and a European Doctorate and PhD in health informatics. The author has had a full-time research position for about 35 years, divided on a university hospital, the software industry and a university, while cross-fertilising the two professions; the time in the industry and the university mainly was dedicated to participation in large and advanced EU R&D Research projects. This combination of professional experience has enabled the present study. The present study was performed outside of any job or grant affiliation, while the author had an emeritus position at the Aalborg University. The author has since the year 2000 been a member of the scientific team describing the Mereon Matrix (for this, see [2]), went on early retirement in 2011 to work full time on the Mereon Matrix, and is independently continuing such scientific investigations on the matrix. Contact information: jytte@brender.dk and jbr@hst.aau.dk. Acknowledgements The author is deeply grateful for her position as Emeritus Assoc. Professor at her former university affiliation at Aalborg University, Dept. of Health Science and Technology, as this enabled a full and free access to most of the original scientific literature. Without this, the present study would have been critically hampered. The author is deeply grateful for continuous brainstorming and constructive feedback on and in the process with her husband, Dr. Peter McNair, retired director of the Medical Genetics Laboratory, KennedyCenter (DK-2600 Glostrup, Denmark). Conflicting Interests The author declares that there was and is no conflicting interests, financial or otherwise, that would or could have influenced the outcome of the study. The author's work on the Mereon Matrix was not

  8. Align the Front End First.

    ERIC Educational Resources Information Center

    Perry, Jim

    1995-01-01

    Discussion of management styles and front-end analysis focuses on a review of Douglas McGregor's theories. Topics include Theories X, Y, and Z; leadership skills; motivational needs of employees; intrinsic and extrinsic rewards; and faulty implementation of instructional systems design processes. (LRW)

  9. Multiple WH-Fronting Constructions.

    ERIC Educational Resources Information Center

    Rudin, Catherine

    The unique position of WH words in Slavic languages is discussed, with specific reference to Bulgarian and Serbo-Croatian. The multiple fronting characteristics of Bulgarian and Serbo-Croatian differ in terms of the following positions and behaviors: extraction from embedded questions; clitic placement and other indications of constituent status;…

  10. Biological Activity at Oceanic Fronts.

    DTIC Science & Technology

    1985-12-01

    al. (1974) in a tidal (shallow sea) front in the English Channel. Most interestingly, a small *-. S jellyfish caught in the downwelling zone sank 28 m...and R.P. Harris. 1984. Photosynthesis, respiration and nitrogen supply of plankton populations in stratified, frontal, and tidally mixed she’-; waters

  11. A New Method for Shear Stabilization of Advanced Tokamak Reactors via Mode Converted Ion Bernstein Waves*

    NASA Astrophysics Data System (ADS)

    Sund, Richard; Scharer, John

    2002-11-01

    We examine a new method for generating sheared flows in advanced tokamak D-T reactors with the goal of creating and controlling internal transport barriers. Ion-Bernstein waves (IBWs) have the recognized capacity to create internal transport barriers through sheared plasma flows resulting from ion absorption. Under reactor conditions, the IBW can be generated by mode conversion of a fast magnetosonic wave incident from the high-field side (HFS) on the second harmonic resonance of a minority hydrogen component, with near 100200 MHz) minimizes parasitic absorption and permits the converted IBW to approach the fifth tritium harmonic. It also facilitates compact antennas and feeds, and efficient fast wave launch. Placement of the 5T absorption layer on the HFS is advantageous for shear production. The scheme is applicable to reactors with aspect ratio < 3 such that the conversion and absorption layers are both on the high field side of the magnetic axis. Various factors (adequate separation of the mode conversion layer from the magnetic axis, concentration of the fast wave near the midplane, large machine size, and plasma elongation) minimize poloidal field effects in the conversion zone and permit a slab analysis. We use a 1-D full-wave code to analyze the conversion and absorption. A 2-D ray-tracing code incorporating poloidal magnetic fields is used to follow the IBW for various equilibria. Within this analysis a weak bean shape appears most favorable. This is an attractive scheme for future advanced tokamak reactors. *Research supported by the Univ. of Wisconsin, Madison

  12. Recent advancements in the electromechanical (E/M) impedance method for structural health monitoring and NDE

    NASA Astrophysics Data System (ADS)

    Giurgiutiu, Victor; Rogers, Craig A.

    1998-07-01

    The emerging electro-mechanical impedance technology has high potential for in-situ health monitoring and NDE of structural systems and complex machinery. At first, the fundamental principles of the electro-mechanical impedance method are briefly reviewed and ways for practical implementation are highlighted. The equations of piezo- electric material response are given, and the coupled electro-mechanical impedance of a piezo-electric wafer transducer as affixed to the monitored structure is discussed. Due to the high frequency operation of this NDE method, wave propagation phenomena are identified as the primary coupling method between the structural substrate and the piezo-electric wafer transducer. Attention is then focused on several recent advancements that have extended the electro-mechanical impedance method into new areas of applications and/or have developed its underlying principles. US Army Construction Engineering Research Laboratory used the electro-mechanical impedance method to monitor damage development in composite overlaid civil infrastructure specimens under full-scale static testing. A simplified E/M impedance measuring technique was employed at the Polytechnic University of Madrid, Spain, to detect damage in GFRP composite specimens. The development of miniaturized `bare-bones' impedance analyzer equipment that could be easily packaged into transponder-size dimensions is being studied at the University of South Carolina. US Army Research Laboratory developed novel piezo-composite film transducers for embedment into composite structures. Disbond gauges for monitoring the structural joints of adhesively bonded rotor blades have been studies in the Mechanical Engineering Department at the University of South Carolina. These recent developments accentuate the importance and benefits of using the electro-mechanical impedance method for on-line health monitoring and damage detection in a variety of applications. Further investigation of the electro

  13. Training toward Advanced 3D Seismic Methods for CO2 Monitoring, Verification, and Accounting

    SciTech Connect

    Christopher Liner

    2012-05-31

    The objective of our work is graduate and undergraduate student training related to improved 3D seismic technology that addresses key challenges related to monitoring movement and containment of CO{sub 2}, specifically better quantification and sensitivity for mapping of caprock integrity, fractures, and other potential leakage pathways. We utilize data and results developed through previous DOE-funded CO{sub 2} characterization project (DE-FG26-06NT42734) at the Dickman Field of Ness County, KS. Dickman is a type locality for the geology that will be encountered for CO{sub 2} sequestration projects from northern Oklahoma across the U.S. midcontinent to Indiana and Illinois. Since its discovery in 1962, the Dickman Field has produced about 1.7 million barrels of oil from porous Mississippian carbonates with a small structural closure at about 4400 ft drilling depth. Project data includes 3.3 square miles of 3D seismic data, 142 wells, with log, some core, and oil/water production data available. Only two wells penetrate the deep saline aquifer. In a previous DOE-funded project, geological and seismic data were integrated to create a geological property model and a flow simulation grid. We believe that sequestration of CO{sub 2} will largely occur in areas of relatively flat geology and simple near surface, similar to Dickman. The challenge is not complex geology, but development of improved, lower-cost methods for detecting natural fractures and subtle faults. Our project used numerical simulation to test methods of gathering multicomponent, full azimuth data ideal for this purpose. Our specific objectives were to apply advanced seismic methods to aide in quantifying reservoir properties and lateral continuity of CO{sub 2} sequestration targets. The purpose of the current project is graduate and undergraduate student training related to improved 3D seismic technology that addresses key challenges related to monitoring movement and containment of CO{sub 2

  14. Fluctuation-controlled front propagation

    NASA Astrophysics Data System (ADS)

    Ridgway, Douglas Thacher

    1997-09-01

    A number of fundamental pattern-forming systems are controlled by fluctuations at the front. These problems involve the interaction of an infinite dimensional probability distribution with a strongly nonlinear, spatially extended pattern-forming system. We have examined fluctuation-controlled growth in the context of the specific problems of diffusion-limited growth and biological evolution. Mean field theory of diffusion-limited growth exhibits a finite time singularity. Near the leading edge of a diffusion-limited front, this leads to acceleration and blowup. This may be resolved, in an ad hoc manner, by introducing a cutoff below which growth is weakened or eliminated (8). This model, referred to as the BLT model, captures a number of qualitative features of global pattern formation in diffusion-limited aggregation: contours of the mean field match contours of averaged particle density in simulation, and the modified mean field theory can form dendritic features not possible in the naive mean field theory. The morphology transition between dendritic and non-dendritic global patterns requires that BLT fronts have a Mullins-Sekerka instability of the wavefront shape, in order to form concave patterns. We compute the stability of BLT fronts numerically, and compare the results to fronts without a cutoff. A significant morphological instability of the BLT fronts exists, with a dominant wavenumber on the scale of the front width. For standard mean field fronts, no instability is found. The naive and ad hoc mean field theories are continuum-deterministic models intended to capture the behavior of a discrete stochastic system. A transformation which maps discrete systems into a continuum model with a singular multiplicative noise is known, however numerical simulations of the continuum stochastic system often give mean field behavior instead of the critical behavior of the discrete system. We have found a new interpretation of the singular noise, based on maintaining

  15. Development of Advanced Life Cycle Costing Methods for Technology Benefit/Cost/Risk Assessment

    NASA Technical Reports Server (NTRS)

    Yackovetsky, Robert (Technical Monitor)

    2002-01-01

    The overall objective of this three-year grant is to provide NASA Langley's System Analysis Branch with improved affordability tools and methods based on probabilistic cost assessment techniques. In order to accomplish this objective, the Aerospace Systems Design Laboratory (ASDL) needs to pursue more detailed affordability, technology impact, and risk prediction methods and to demonstrate them on variety of advanced commercial transports. The affordability assessment, which is a cornerstone of ASDL methods, relies on the Aircraft Life Cycle Cost Analysis (ALCCA) program originally developed by NASA Ames Research Center and enhanced by ASDL. This grant proposed to improve ALCCA in support of the project objective by updating the research, design, test, and evaluation cost module, as well as the engine development cost module. Investigations into enhancements to ALCCA include improved engine development cost, process based costing, supportability cost, and system reliability with airline loss of revenue for system downtime. A probabilistic, stand-alone version of ALCCA/FLOPS will also be developed under this grant in order to capture the uncertainty involved in technology assessments. FLOPS (FLight Optimization System program) is an aircraft synthesis and sizing code developed by NASA Langley Research Center. This probabilistic version of the coupled program will be used within a Technology Impact Forecasting (TIF) method to determine what types of technologies would have to be infused in a system in order to meet customer requirements. A probabilistic analysis of the CER's (cost estimating relationships) within ALCCA will also be carried out under this contract in order to gain some insight as to the most influential costs and the impact that code fidelity could have on future RDS (Robust Design Simulation) studies.

  16. Measurement of fracture toughness by nanoindentation methods: Recent advances and future challenges

    SciTech Connect

    Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; Pharr, George M.

    2015-04-30

    In this study, we describe recent advances and developments for the measurement of fracture toughness at small scales by the use of nanoindentation-based methods including techniques based on micro-cantilever beam bending and micro-pillar splitting. A critical comparison of the techniques is made by testing a selected group of bulk and thin film materials. For pillar splitting, cohesive zone finite element simulations are used to validate a simple relationship between the critical load at failure, the pillar radius, and the fracture toughness for a range of material properties and coating/substrate combinations. The minimum pillar diameter required for nucleation and growth of a crack during indentation is also estimated. An analysis of pillar splitting for a film on a dissimilar substrate material shows that the critical load for splitting is relatively insensitive to the substrate compliance for a large range of material properties. Experimental results from a selected group of materials show good agreement between single cantilever and pillar splitting methods, while a discrepancy of ~25% is found between the pillar splitting technique and double-cantilever testing. It is concluded that both the micro-cantilever and pillar splitting techniques are valuable methods for micro-scale assessment of fracture toughness of brittle ceramics, provided the underlying assumptions can be validated. Although the pillar splitting method has some advantages because of the simplicity of sample preparation and testing, it is not applicable to most metals because their higher toughness prevents splitting, and in this case, micro-cantilever bend testing is preferred.

  17. Measurement of fracture toughness by nanoindentation methods: Recent advances and future challenges

    DOE PAGES

    Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; ...

    2015-04-30

    In this study, we describe recent advances and developments for the measurement of fracture toughness at small scales by the use of nanoindentation-based methods including techniques based on micro-cantilever beam bending and micro-pillar splitting. A critical comparison of the techniques is made by testing a selected group of bulk and thin film materials. For pillar splitting, cohesive zone finite element simulations are used to validate a simple relationship between the critical load at failure, the pillar radius, and the fracture toughness for a range of material properties and coating/substrate combinations. The minimum pillar diameter required for nucleation and growth ofmore » a crack during indentation is also estimated. An analysis of pillar splitting for a film on a dissimilar substrate material shows that the critical load for splitting is relatively insensitive to the substrate compliance for a large range of material properties. Experimental results from a selected group of materials show good agreement between single cantilever and pillar splitting methods, while a discrepancy of ~25% is found between the pillar splitting technique and double-cantilever testing. It is concluded that both the micro-cantilever and pillar splitting techniques are valuable methods for micro-scale assessment of fracture toughness of brittle ceramics, provided the underlying assumptions can be validated. Although the pillar splitting method has some advantages because of the simplicity of sample preparation and testing, it is not applicable to most metals because their higher toughness prevents splitting, and in this case, micro-cantilever bend testing is preferred.« less

  18. Recent advances in the modeling of plasmas with the Particle-In-Cell methods

    NASA Astrophysics Data System (ADS)

    Vay, Jean-Luc; Lehe, Remi; Vincenti, Henri; Godfrey, Brendan; Lee, Patrick; Haber, Irv

    2015-11-01

    The Particle-In-Cell (PIC) approach is the method of choice for self-consistent simulations of plasmas from first principles. The fundamentals of the PIC method were established decades ago but improvements or variations are continuously being proposed. We report on several recent advances in PIC related algorithms, including: (a) detailed analysis of the numerical Cherenkov instability and its remediation, (b) analytic pseudo-spectral electromagnetic solvers in Cartesian and cylindrical (with azimuthal modes decomposition) geometries, (c) arbitrary-order finite-difference and generalized pseudo-spectral Maxwell solvers, (d) novel analysis of Maxwell's solvers' stencil variation and truncation, in application to domain decomposition strategies and implementation of Perfectly Matched Layers in high-order and pseudo-spectral solvers. Work supported by US-DOE Contracts DE-AC02-05CH11231 and the US-DOE SciDAC program ComPASS. Used resources of NERSC, supported by US-DOE Contract DE-AC02-05CH11231.

  19. Advanced development of the boundary element method for steady-state heat conduction

    NASA Technical Reports Server (NTRS)

    Dargush, G. F.; Banerjee, Prasanta K.

    1989-01-01

    Considerable progress has been made in recent years toward advancing the state-of-the-art in solid mechanics boundary element technology. In the present work, much of this new technology is applied in the development of a general-purpose boundary element method (BEM) for steady-state heat conduction. In particular, the BEM implementation involves the use of higher-order conforming elements, self-adaptive integration and multi-region capability. Two- and three-dimensional, as well as axisymmetric analysis, are incorporated within a unified framework. In addition, techniques are introduced for the calculation of boundary flux, and for the inclusion of thermal resistance across interfaces. As a final extension, an efficient formulation is developed for the analysis of solid three-dimensional bodies with embedded holes. For this last class of problems, the new BEM formulation is particularly attractive, since use of the alternatives (i.e. finite element or finite difference methods) is not practical. A number of detailed examples illustrate the suitability and robustness of the present approach for steady-state heat conduction.

  20. Advanced Methods for Acoustic and Thrust Benefits for Aircraft Engine Nozzles

    NASA Technical Reports Server (NTRS)

    Morgan, Morris H., III; Gilinsky, Mikhail M.

    2000-01-01

    The Fluid Mechanics and Acoustics Laboratory (FM&AL) was established At Hampton University in June of 1996. In addition, the FM&AL jointly conducted research with the Central AeroHydrodynamics Institute (TsAGI, Moscow) in Russia under a 2.5 year Civilian Research and Development Foundation (CRDF). The goals of the FM&AL programs are two fold: 1) to improve the working efficiency of the FM&AL team in generating new innovative ideas and in conducting research in the field of fluid dynamics and acoustics, basically for improvement of supersonic and subsonic aircraft engines, and 2) to attract promising minority students to this research and training and, in cooperation with other HU departments, to teach them basic knowledge in Aerodynamics, Gas Dynamics, and Theoretical and Experimental Methods in Aeroacoustics and Computational Fluid Dynamics (CFD). The research at the FM&AL supports reduction schemes associated with the emission of engine pollutants for commercial aircraft and concepts for reduction of observables for military aircraft. These research endeavors relate to the goals of the NASA Strategic Enterprise in Aeronautics concerning the development of environmentally acceptable aircraft. It is in this precise area, where the US aircraft industry, academia, and Government are in great need of trained professionals and which is a high priority goal of the Minority University Research and Education (MUREP) Program, that the HU FM&AL can make its most important contribution. This project already benefits NASA and HU because: First, the innovation, testing, and further development of new techniques for advanced propulsion systems are necessary for the successful attainment of the NASA Long Term Goals in Aeronautics and Space Transportation Technology (ASTT) including Global Civil Aviation, Revolutionary Technology Leaps, Access to Space, R&D Services, and the economic competitiveness of the US Aircraft Industry in the 2 1 st century. Secondly, the joint

  1. Reaction front formation in contaminant plumes.

    PubMed

    Cribbin, Laura B; Winstanley, Henry F; Mitchell, Sarah L; Fowler, Andrew C; Sander, Graham C

    2014-12-15

    The formation of successive fronts in contaminated groundwater plumes by subsoil bacterial action is a commonly accepted feature of their propagation, but it is not obviously clear from a mathematical standpoint quite how such fronts are formed or propagate. In this paper we show that these can be explained by combining classical reaction-diffusion theory involving just two reactants (oxidant and reductant), and a secondary reaction in which a reactant on one side of such a front is (re-)formed on the other side of the front via diffusion of its product across the front. We give approximate asymptotic solutions for the reactant profiles, and the propagation rate of the front.

  2. An Advanced Electrospinning Method of Fabricating Nanofibrous Patterned Architectures with Controlled Deposition and Desired Alignment

    NASA Astrophysics Data System (ADS)

    Rasel, Sheikh Md

    We introduce a versatile advanced method of electrospinning for fabricating various kinds of nanofibrous patterns along with desired alignment, controlled amount of deposition and locally variable density into the architectures. In this method, we employed multiple electrodes whose potentials have been altered in milliseconds with the help of microprocessor based control system. Therefore, key success of this method was that the electrical field as well as charge carrying fibers could be switched shortly from one electrode's location to another, as a result, electrospun fibers could be deposited on the designated areas with desired alignment. A wide range of nanofibrous patterned architectures were constructed using proper arrangement of multiple electrodes. By controlling the concurrent activation time of two adjacent electrodes, we demonstrated that amount of fibers going into the pattern can be adjusted and desired alignment in electrospun fibers can be obtained. We also revealed that the deposition density of electrospun fibers in different areas of patterned architectures can be varied. We showed that by controlling the deposition time between two adjacent electrodes, a number of functionally graded patterns can be generated with uniaxial alignment. We also demonstrated that this handy method was capable of producing random, aligned, and multidirectional nanofibrous mats by engaging a number of electrodes and switching them in desired patterns. A comprehensive study using finite element method was carried out to understand the effects of electrical field. Simulation results revealed that electrical field strength alters shortly based on electrode control switch patterns. Nanofibrous polyvinyl alcohol (PVA) scaffolds and its composite reinforced with wollastonite and wood flour were fabricated using rotating drum electrospinning technique. Morphological, mechanical, and thermal, properties were characterized on PVA/wollastonite and PVA/wood flour nanocomposites

  3. 7 CFR 1744.68 - Order and method of advances of telephone loan funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... loan from which the funds are drawn. (b) The first or subsequent advances of loan funds may be... of RUS and RTB funds may request advances by wire service only for amounts greater than $500,000 or...,000 can be sent by wire service. (e) The following information shall be included with the FRS:...

  4. Advancing Higher Education with Mobile Learning Technologies: Cases, Trends, and Inquiry-Based Methods

    ERIC Educational Resources Information Center

    Keengwe, Jared, Ed.; Maxfield, Marian B., Ed.

    2015-01-01

    Rapid advancements in technology are creating new opportunities for educators to enhance their classroom techniques with digital learning resources. Once used solely outside of the classroom, smartphones, tablets, and e-readers are becoming common in many school settings. "Advancing Higher Education with Mobile Learning Technologies: Cases,…

  5. BOOK REVIEW: Advanced Topics in Computational Partial Differential Equations: Numerical Methods and Diffpack Programming

    NASA Astrophysics Data System (ADS)

    Katsaounis, T. D.

    2005-02-01

    The scope of this book is to present well known simple and advanced numerical methods for solving partial differential equations (PDEs) and how to implement these methods using the programming environment of the software package Diffpack. A basic background in PDEs and numerical methods is required by the potential reader. Further, a basic knowledge of the finite element method and its implementation in one and two space dimensions is required. The authors claim that no prior knowledge of the package Diffpack is required, which is true, but the reader should be at least familiar with an object oriented programming language like C++ in order to better comprehend the programming environment of Diffpack. Certainly, a prior knowledge or usage of Diffpack would be a great advantage to the reader. The book consists of 15 chapters, each one written by one or more authors. Each chapter is basically divided into two parts: the first part is about mathematical models described by PDEs and numerical methods to solve these models and the second part describes how to implement the numerical methods using the programming environment of Diffpack. Each chapter closes with a list of references on its subject. The first nine chapters cover well known numerical methods for solving the basic types of PDEs. Further, programming techniques on the serial as well as on the parallel implementation of numerical methods are also included in these chapters. The last five chapters are dedicated to applications, modelled by PDEs, in a variety of fields. The first chapter is an introduction to parallel processing. It covers fundamentals of parallel processing in a simple and concrete way and no prior knowledge of the subject is required. Examples of parallel implementation of basic linear algebra operations are presented using the Message Passing Interface (MPI) programming environment. Here, some knowledge of MPI routines is required by the reader. Examples solving in parallel simple PDEs using

  6. Front and backside processed thin film electronic devices

    DOEpatents

    Yuan, Hao-Chih; Wang, Guogong; Eriksson, Mark A.; Evans, Paul G.; Lagally, Max G.; Ma, Zhenqiang

    2010-10-12

    This invention provides methods for fabricating thin film electronic devices with both front- and backside processing capabilities. Using these methods, high temperature processing steps may be carried out during both frontside and backside processing. The methods are well-suited for fabricating back-gate and double-gate field effect transistors, double-sided bipolar transistors and 3D integrated circuits.

  7. Detecting method of subjects' 3D positions and experimental advanced camera control system

    NASA Astrophysics Data System (ADS)

    Kato, Daiichiro; Abe, Kazuo; Ishikawa, Akio; Yamada, Mitsuho; Suzuki, Takahito; Kuwashima, Shigesumi

    1997-04-01

    Steady progress is being made in the development of an intelligent robot camera capable of automatically shooting pictures with a powerful sense of reality or tracking objects whose shooting requires advanced techniques. Currently, only experienced broadcasting cameramen can provide these pictures.TO develop an intelligent robot camera with these abilities, we need to clearly understand how a broadcasting cameraman assesses his shooting situation and how his camera is moved during shooting. We use a real- time analyzer to study a cameraman's work and his gaze movements at studios and during sports broadcasts. This time, we have developed a detecting method of subjects' 3D positions and an experimental camera control system to help us further understand the movements required for an intelligent robot camera. The features are as follows: (1) Two sensor cameras shoot a moving subject and detect colors, producing its 3D coordinates. (2) Capable of driving a camera based on camera movement data obtained by a real-time analyzer. 'Moving shoot' is the name we have given to the object position detection technology on which this system is based. We used it in a soccer game, producing computer graphics showing how players moved. These results will also be reported.

  8. Advanced three-dimensional scan methods in the nanopositioning and nanomeasuring machine

    NASA Astrophysics Data System (ADS)

    Hausotte, T.; Percle, B.; Jäger, G.

    2009-08-01

    The nanopositioning and nanomeasuring machine developed at the Ilmenau University of Technology was originally designed for surface measurements within a measuring volume of 25 mm × 25 mm × 5 mm. The interferometric length measuring and drive systems make it possible to move the stage with a resolution of 0.1 nm and a positioning uncertainty of less than 10 nm in all three axes. Various measuring tasks are possible depending on the installed probe system. Most of the sensors utilized are one-dimensional surface probes; however, some tasks require measuring sidewalls and other three-dimensional features. A new control system, based on the I++ DME specification, was implemented in the device. The I++ DME scan functions were improved and special scan functions added to allow advanced three-dimensional scan methods, further fulfilling the demands of scanning force microscopy and micro-coordinate measurements. This work gives an overview of these new functions and the application of them for several different measurements.

  9. Advanced Methods for Aircraft Engine Thrust and Noise Benefits: Nozzle-Inlet Flow Analysis

    NASA Technical Reports Server (NTRS)

    Morgan, Morris H.; Gilinsky, Mikhail; Patel, Kaushal; Coston, Calvin; Blankson, Isaiah M.

    2003-01-01

    The research is focused on a wide regime of problems in the propulsion field as well as in experimental testing and theoretical and numerical simulation analyses for advanced aircraft and rocket engines. Results obtained are based on analytical methods, numerical simulations and experimental tests at the NASA LaRC and Hampton University computer complexes and experimental facilities. The main objective of this research is injection, mixing and combustion enhancement in propulsion systems. The sub-projects in the reporting period are: (A) Aero-performance and acoustics of Telescope-shaped designs. The work included a pylon set application for SCRAMJET. (B) An analysis of sharp-edged nozzle exit designs for effective fuel injection into the flow stream in air-breathing engines: triangular-round and diamond-round nozzles. (C) Measurement technique improvements for the HU Low Speed Wind Tunnel (HU LSWT) including an automatic data acquisition system and a two component (drag-lift) balance system. In addition, a course in the field of aerodynamics was developed for the teaching and training of HU students.

  10. A hybrid method for damage detection and quantification in advanced X-COR composite structures

    NASA Astrophysics Data System (ADS)

    Neerukatti, Rajesh Kumar; Rajadas, Abhishek; Borkowski, Luke; Chattopadhyay, Aditi; Huff, Daniel W.

    2016-04-01

    Advanced composite structures, such as foam core carbon fiber reinforced polymer composites, are increasingly being used in applications which require high strength, high in-plane and flexural stiffness, and low weight. However, the presence of in situ damage due to manufacturing defects and/or service conditions can complicate the failure mechanisms and compromise their strength and reliability. In this paper, the capability of detecting damages such as delaminations and foam-core separations in X-COR composite structures using non-destructive evaluation (NDE) and structural health monitoring (SHM) techniques is investigated. Two NDE techniques, flash thermography and low frequency ultrasonics, were used to detect and quantify the damage size and locations. Macro fiber composites (MFCs) were used as actuators and sensors to study the interaction of Lamb waves with delaminations and foam-core separations. The results indicate that both flash thermography and low frequency ultrasonics were capable of detecting damage in X-COR sandwich structures, although low frequency ultrasonic methods were capable of detecting through thickness damages more accurately than flash thermography. It was also observed that the presence of foam-core separations significantly changes the wave behavior when compared to delamination, which complicates the use of wave based SHM techniques. Further, a wave propagation model was developed to model the wave interaction with damages at different locations on the X-COR sandwich plate.

  11. Treatment of yellow water by membrane separations and advanced oxidation methods.

    PubMed

    Lazarova, Z; Spendlingwimmer, R

    2008-01-01

    Comparative experimental study is performed on purification of yellow wastewaters separated and collected in solarCity, Linz, Austria. Three membrane methods (micro-, ultra-, and nano-filtration), and two advanced oxidations (gamma radiation and electrochemical oxidation) were applied. Best results concerning the removal of pharmaceuticals and hormones from urine by membrane separation were achieved using the membrane NF-200 (FilmTec). Pharmaceuticals (ibuprofen and diclofenac), and hormones (oestrone, beta-oestradiol, ethenyloestradiol, oestriol) were removed completely from urine. NF-separation also has some disadvantages: losses of urea, and lowering the conductivity in the product (permeate). The retentates (concentrates) received have to be treated further by oxidation to destroy the "problem" compounds. The results showed that electrochemical oxidation is more suitable than gamma radiation. Gamma-radiation with intensities higher than 10 kGy has to be applied for efficiently destroying of ibuprofen, and especially diclofenac. A high quantity of intermediate "problem" substances with oestrone structure was formed during the gamma oxidation of hormone containing urine samples. The electrochemical oxidation can be successfully applied for elimination of pharmaceuticals such as diclofenac, and hormones (oestrone, beta-oestradiol) from yellow wastewater without loss of urea (nitrogen fertiliser).

  12. Degradation of herbicide 4-chlorophenoxyacetic acid by advanced electrochemical oxidation methods.

    PubMed

    Boye, Birame; Dieng, Momar M; Brillas, Enric

    2002-07-01

    The herbicide 4-chlorophenoxyacetic acid (4-CPA) has been degraded in aqueous medium by advanced electrochemical oxidation processes such as electro-Fenton and photoelectro-Fenton with UV light, using an undivided cell containing a Pt anode. In these environmentally clean methods, the main oxidant is the hydroxyl radical produced from Fenton's reaction between Fe2+ added to the medium and H2O2 electrogenerated from an 02-diffusion cathode. Solutions of a 4-CPA concentration <400 ppm within the pH range of 2.0-6.0 at 35 degrees C can be completely mineralized at low current by photoelectro-Fenton, while electro-Fenton leads to ca. 80% of mineralization. 4-CPA is much more slowly degraded by anodic oxidation in the absence and presence of electrogenerated H2O2. 4-Chlorophenol, 4-chlorocatechol, and hydroquinone are identified as aromatic intermediates by CG-MS and quantified by reverse-phase chromatography. Further oxidation of these chloroderivatives yields stable chloride ions. Generated carboxylic acids such as glycolic, glyoxylic, formic, malic, maleic, fumaric, and oxalic are followed by ion exclusion chromatography. The highest mineralization rate found for photoelectro-Fenton is accounted for by the fast photodecomposition of complexes of Fe3+ with such short-chain acids, mainly oxalic acid, under the action of UV light.

  13. Development and validation of an advanced low-order panel method

    NASA Technical Reports Server (NTRS)

    Ashby, Dale L.; Iguchi, Steven K.; Dudley, Michael

    1988-01-01

    A low-order potential-flow panel code, PMARC, for modeling complex three-dimensional geometries, is currently being developed at NASA Ames Research Center. The PMARC code was derived from a code named VSAERO that was developed for Ames Research Center by Analytical Methods, Inc. In addition to modeling potential flow over three-dimensional geometries, the present version of PMARC includes several advanced features such as an internal flow model, a simple jet wake model, and a time-stepping wake model. Data management within the code was optimized by the use of adjustable size arrays for rapidly changing the size capability of the code, reorganization of the output file and adopting a new plot file format. Preliminary versions of a geometry preprocessor and a geometry/aerodynamic data postprocessor are also available for use with PMARC. Several test cases are discussed to highlight the capabilities of the internal flow model, the jet wake model, and the time-stepping wake model.

  14. Response monitoring using quantitative ultrasound methods and supervised dictionary learning in locally advanced breast cancer

    NASA Astrophysics Data System (ADS)

    Gangeh, Mehrdad J.; Fung, Brandon; Tadayyon, Hadi; Tran, William T.; Czarnota, Gregory J.

    2016-03-01

    A non-invasive computer-aided-theragnosis (CAT) system was developed for the early assessment of responses to neoadjuvant chemotherapy in patients with locally advanced breast cancer. The CAT system was based on quantitative ultrasound spectroscopy methods comprising several modules including feature extraction, a metric to measure the dissimilarity between "pre-" and "mid-treatment" scans, and a supervised learning algorithm for the classification of patients to responders/non-responders. One major requirement for the successful design of a high-performance CAT system is to accurately measure the changes in parametric maps before treatment onset and during the course of treatment. To this end, a unified framework based on Hilbert-Schmidt independence criterion (HSIC) was used for the design of feature extraction from parametric maps and the dissimilarity measure between the "pre-" and "mid-treatment" scans. For the feature extraction, HSIC was used to design a supervised dictionary learning (SDL) method by maximizing the dependency between the scans taken from "pre-" and "mid-treatment" with "dummy labels" given to the scans. For the dissimilarity measure, an HSIC-based metric was employed to effectively measure the changes in parametric maps as an indication of treatment effectiveness. The HSIC-based feature extraction and dissimilarity measure used a kernel function to nonlinearly transform input vectors into a higher dimensional feature space and computed the population means in the new space, where enhanced group separability was ideally obtained. The results of the classification using the developed CAT system indicated an improvement of performance compared to a CAT system with basic features using histogram of intensity.

  15. Quantifying export flows of used electronics: advanced methods to resolve used goods within trade data.

    PubMed

    Duan, Huabo; Miller, T Reed; Gregory, Jeremy; Kirchain, Randolph

    2014-03-18

    There is limited convincing quantitative data on the export of used electronics from the United States (U.S.). Thus, we advance a methodology to quantify the export flows of whole units of used electronics from the U.S. using detailed export trade data, and demonstrate the methodology using laptops. Since used electronics are not explicitly identified in export trade data, we hypothesize that exports with a low unit value below a used-new threshold specific to a destination world region are used. The importance of using the most disaggregated trade data set available when resolving used and new goods is illustrated. Two detailed U.S. export trade data sets were combined to arrive at quantities and unit values for each port, mode of transport, month, trade partner country, and trade code. We add rigor to the determination of the used-new threshold by utilizing both the Neighborhood valley-emphasis method (NVEM) and published sales prices. This analysis found that 748 to 1199 thousand units of used laptops were exported from the U.S. in 2010, of which 78-81% are destined for non-OECD countries. Asia was found to be the largest destination of used laptop exports across all used-new threshold methods. Latin American and the Caribbean was the second largest recipient of these exports. North America and Europe also received used laptops from the U.S. Only a small fraction of used laptops was exported to Africa. However, these quantities are lower bound estimates because not all shipments of used laptops may be shipped using the proper laptop trade code. Still, this approach has the potential to give insight into the quantity and destinations of the exports if applied to all used electronics product types across a series of years.

  16. Phyllotaxis, Pushed Pattern-Forming Fronts, and Optimal Packing

    NASA Astrophysics Data System (ADS)

    Pennybacker, Matthew; Newell, Alan C.

    2013-06-01

    We demonstrate that the pattern forming partial differential equation derived from the auxin distribution model proposed by Meyerowitz, Traas, and others gives rise to all spiral phyllotaxis properties observed on plants. We show how the advancing pushed pattern front chooses spiral families enumerated by Fibonacci sequences with all attendant self-similar properties, a new amplitude invariant curve, and connect the results with the optimal packing based algorithms previously used to explain phyllotaxis. Our results allow us to make experimentally testable predictions.

  17. Development of new methods and polyphosphazene chemistries for advanced materials applications

    NASA Astrophysics Data System (ADS)

    Hindenlang, Mark D.

    The work described within this thesis focuses on the design, synthesis, and characterization of new phosphazenes with potential in advanced materials applications. Additionally, these unique polymers required the development of novel reaction methods or the investigation of new phosphazene chemistry to achieve their synthesis. Chapter 1 lays out some of the basic principles and fundamentals of polymer chemistry. Chapter 2 investigates the use of iodinated polyphosphazenes as x-ray opaque materials. Single-substituent polymers with 4-iodophenoxy or 4-iodophenylanaline ethyl ester units as the only side groups were prepared. Although a single-substitutent polymer with 3,5-diiodotyrosine ethyl ester groups was difficult to synthesize, probably because of steric hindrance, mixed-substituent polymers that contained the non-iodinated ethyl esters of glycyine, alanine, or phenylalanine plus a corresponding iodinated substituent, could be synthesized. Multinuclear NMR spectroscopy was used to follow the substitution of side groups onto the phosphazene back bone and judge the ratio of substituents. Chapter 3 details the initial investigation into 3,4-dihydroxy-L-phenylalanine ethyl ester and dopamine substituted polyphosphazenes that could be applied to a number of applications. L-DOPAEE was acetonide protected to prevent crosslinking reactions by the catechole functionality. Cyclic small molecule studies and macromolecular substitution reactions on the linear high polymer were conducted with the protected L-DOPA. Continuing studies into protection of the dopamine catechol have elucidated a viable method for the synthesis of amino-linked dopamine polymers. Chapter 4 describes a method for the synthesis of phosphazenes with quaternary amine complexes as potential antibacterial agents. Replacement reactions of pyridine alkoxides and chlorophosphazenes were first attempted at the small molecule level to study the reactivities of pyridine alkoxides. The formation of an

  18. Advanced Methods for Aircraft Engine Thrust and Noise Benefits: Nozzle-Inlet Flow Analysis

    NASA Technical Reports Server (NTRS)

    Morgan, Morris H.; Gilinsky, Mikhail M.

    2001-01-01

    Three connected sub-projects were conducted under reported project. Partially, these sub-projects are directed to solving the problems conducted by the HU/FM&AL under two other NASA grants. The fundamental idea uniting these projects is to use untraditional 3D corrugated nozzle designs and additional methods for exhaust jet noise reduction without essential thrust lost and even with thrust augmentation. Such additional approaches are: (1) to add some solid, fluid, or gas mass at discrete locations to the main supersonic gas stream to minimize the negative influence of strong shock waves forming in propulsion systems; this mass addition may be accompanied by heat addition to the main stream as a result of the fuel combustion or by cooling of this stream as a result of the liquid mass evaporation and boiling; (2) to use porous or permeable nozzles and additional shells at the nozzle exit for preliminary cooling of exhaust hot jet and pressure compensation for non-design conditions (so-called continuous ejector with small mass flow rate; and (3) to propose and analyze new effective methods fuel injection into flow stream in air-breathing engines. Note that all these problems were formulated based on detailed descriptions of the main experimental facts observed at NASA Glenn Research Center. Basically, the HU/FM&AL Team has been involved in joint research with the purpose of finding theoretical explanations for experimental facts and the creation of the accurate numerical simulation technique and prediction theory for solutions for current problems in propulsion systems solved by NASA and Navy agencies. The research is focused on a wide regime of problems in the propulsion field as well as in experimental testing and theoretical and numerical simulation analysis for advanced aircraft and rocket engines. The F&AL Team uses analytical methods, numerical simulations, and possible experimental tests at the Hampton University campus. We will present some management activity

  19. Advanced Optical Diagnostic Methods for Describing Fuel Injection and Combustion Flowfield Phenomena

    NASA Technical Reports Server (NTRS)

    Locke, Randy J.; Hicks, Yolanda R.; Anderson, Robert C.

    2004-01-01

    Over the past decade advanced optical diagnostic techniques have evolved and matured to a point where they are now widely applied in the interrogation of high pressure combusting flows. At NASA Glenn Research Center (GRC), imaging techniques have been used successfully in on-going work to develop the next generation of commercial aircraft gas turbine combustors. This work has centered on providing a means by which researchers and designers can obtain direct visual observation and measurements of the fuel injection/mixing/combustion processes and combustor flowfield in two- and three-dimensional views at actual operational conditions. Obtaining a thorough understanding of the chemical and physical processes at the extreme operating conditions of the next generation of combustors is critical to reducing emissions and increasing fuel efficiency. To accomplish this and other tasks, the diagnostic team at GRC has designed and constructed optically accessible, high pressurer high temperature flame tubes and sectar rigs capable of optically probing the 20-60 atm flowfields of these aero-combustors. Among the techniques employed at GRC are planar laser-induced fluorescence (PLIF) for imaging molecular species as well as liquid and gaseous fuel; planar light scattering (PLS) for imaging fuel sprays and droplets; and spontaneous Raman scattering for species and temperature measurement. Using these techniques, optical measurements never before possible have been made in the actual environments of liquid fueled gas turbines. 2-D mapping of such parameters as species (e.g. OH-, NO and kerosene-based jet fuel) distribution, injector spray angle, and fuel/air distribution are just some of the measurements that are now routinely made. Optical imaging has also provided prompt feedback to researchers regarding the effects of changes in the fuel injector configuration on both combustor performance and flowfield character. Several injector design modifications and improvements have

  20. Probing the Detailed Seismic Velocity Structure of Subduction Zones Using Advanced Seismic Tomography Methods

    NASA Astrophysics Data System (ADS)

    Zhang, H.; Thurber, C. H.

    2005-12-01

    -P times in a manner similar to double-difference tomography. Obtaining a reliable Vp/Vs model of the subduction zone is more helpful for understanding its mechanical and petrologic properties. Our applications of the original version of double-difference tomography to several subduction zones beneath northern Honshu, Japan, the Wellington region, New Zealand, and Alaska, United States, have shown evident velocity variations within and around the subducting slab, which likely is evidence of dehydration reactions of various hydrous minerals that are hypothesized to be responsible for intermediate depth earthquakes. We will show the new velocity models for these subduction zones by applying our advanced tomographic methods.

  1. Advances in EBSD Technology: A Powerful Method for the Analysis of Impactites and Meteorites

    NASA Astrophysics Data System (ADS)

    Palasse, L.; Goran, D.; Schwager, T.; Berlin, J.; Salge, T.

    2012-09-01

    Electron backscatter diffraction is an analytical technique for assessing the petrographic texture of a rock and the crystallographic orientation of minerals. Recent advances in software and hardware can help to understand impact and shock processes.

  2. Advanced Methods for Aircraft Engine Thrust and Noise Benefits: Nozzle-Inlet Flow Analysis

    NASA Technical Reports Server (NTRS)

    Gilinsky, Mikhail; Morgan, Morris H.; Povitsky, Alex; Schkolnikov, Natalia; Njoroge, Norman; Coston, Calvin; Blankson, Isaiah M.

    2001-01-01

    The Fluid Mechanics and Acoustics Laboratory at Hampton University (HU/FM&AL) jointly with the NASA Glenn Research Center has conducted four connected subprojects under the reporting project. Basically, the HU/FM&AL Team has been involved in joint research with the purpose of theoretical explanation of experimental facts and creation of accurate numerical simulation techniques and prediction theory for solution of current problems in propulsion systems of interest to the NAVY and NASA agencies. This work is also supported by joint research between the NASA GRC and the Institute of Mechanics at Moscow State University (IM/MSU) in Russia under a CRDF grant. The research is focused on a wide regime of problems in the propulsion field as well as in experimental testing and theoretical and numerical simulation analyses for advanced aircraft and rocket engines. The FM&AL Team uses analytical methods, numerical simulations and possible experimental tests at the Hampton University campus. The fundamental idea uniting these subprojects is to use nontraditional 3D corrugated and composite nozzle and inlet designs and additional methods for exhaust jet noise reduction without essential thrust loss and even with thrust augmentation. These subprojects are: (1) Aeroperformance and acoustics of Bluebell-shaped and Telescope-shaped designs; (2) An analysis of sharp-edged nozzle exit designs for effective fuel injection into the flow stream in air-breathing engines: triangular-round, diamond-round and other nozzles; (3) Measurement technique improvement for the HU Low Speed Wind Tunnel; a new course in the field of aerodynamics, teaching and training of HU students; experimental tests of Mobius-shaped screws: research and training; (4) Supersonic inlet shape optimization. The main outcomes during this reporting period are: (l) Publications: The AIAA Paper #00-3170 was presented at the 36th AIAA/ASME/SAE/ASEE Joint Propulsion Conference, 17-19 June, 2000, Huntsville, AL. The AIAA

  3. Advanced treatment planning methods for efficient radiation therapy with laser accelerated proton and ion beams

    SciTech Connect

    Schell, Stefan; Wilkens, Jan J.

    2010-10-15

    lateral clustering and reduce the number of particles that have to be blocked in the beam delivery system. Furthermore, the optimization routine can be adjusted to reduce the number of dose spots and laser shots. The authors implemented these methods into a research treatment planning system for laser accelerated particles. Results: The authors' proposed methods can decrease the amount of secondary radiation produced when blocking particles with wrong energies or when reducing the total number of particles from one laser shot. Additionally, caused by the efficient use of the beam, the treatment time is reduced considerably. Both improvements can be achieved without extensively changing the quality of the treatment plan since conventional intensity modulated particle therapy usually includes a certain amount of unused degrees of freedom which can be used to adapt to laser specific properties. Conclusions: The advanced beam delivery and treatment planning methods reduce the need to have a perfect laser-based accelerator reproducing the properties of conventional accelerators that might not be possible without increasing treatment time and secondary radiation to the patient. The authors show how some of the differences to conventional beams can be overcome and efficiently used for radiation treatment.

  4. Multi-channel pre-beamformed data acquisition system for research on advanced ultrasound imaging methods.

    PubMed

    Cheung, Chris C P; Yu, Alfred C H; Salimi, Nazila; Yiu, Billy Y S; Tsang, Ivan K H; Kerby, Benjamin; Azar, Reza Zahiri; Dickie, Kris

    2012-02-01

    The lack of open access to the pre-beamformed data of an ultrasound scanner has limited the research of novel imaging methods to a few privileged laboratories. To address this need, we have developed a pre-beamformed data acquisition (DAQ) system that can collect data over 128 array elements in parallel from the Ultrasonix series of research-purpose ultrasound scanners. Our DAQ system comprises three system-level blocks: 1) a connector board that interfaces with the array probe and the scanner through a probe connector port; 2) a main board that triggers DAQ and controls data transfer to a computer; and 3) four receiver boards that are each responsible for acquiring 32 channels of digitized raw data and storing them to the on-board memory. This system can acquire pre-beamformed data with 12-bit resolution when using a 40-MHz sampling rate. It houses a 16 GB RAM buffer that is sufficient to store 128 channels of pre-beamformed data for 8000 to 25 000 transmit firings, depending on imaging depth; corresponding to nearly a 2-s period in typical imaging setups. Following the acquisition, the data can be transferred through a USB 2.0 link to a computer for offline processing and analysis. To evaluate the feasibility of using the DAQ system for advanced imaging research, two proof-of-concept investigations have been conducted on beamforming and plane-wave B-flow imaging. Results show that adaptive beamforming algorithms such as the minimum variance approach can generate sharper images of a wire cross-section whose diameter is equal to the imaging wavelength (150 μm in our example). Also, planewave B-flow imaging can provide more consistent visualization of blood speckle movement given the higher temporal resolution of this imaging approach (2500 fps in our example).

  5. Early identification of cervical neoplasia with Raman spectroscopy and advanced methods for biomedical applications

    NASA Astrophysics Data System (ADS)

    Jess, Phillip R. T.; Smith, Daniel D. W.; Mazilu, Michael; Cormack, Iain; Riches, Andrew C.; Herrington, C. Simon; Dholakia, Kishan

    2008-02-01

    Early detection of malignant tumours, or their precursor lesions, can dramatically improve patient outcome. High risk human Papillomavirus (HPV), particularly HPV16, infection can lead to the initiation and development of uterine cervical neoplasia. Bearing this in mind the identification of the effects of HPV infection may have clinical value. In this manuscript we investigate the application of Raman microspectroscopy to detect the presence of HPV in cultured cells when compared with normal cells. We also investigate the effect of sample fixation, which is a common clinical practice, on the ability of Raman spectroscopy to detect the presence of HPV. Raman spectra were acquired from Primary Human Keratinocytes (PHK), PHK expressing the E7 gene of HPV 16 (PHK E7) and CaSki cells, an HPV16 containing cervical carcinoma derived cell line. The average Raman spectra display variations, mostly in peaks relating to DNA and proteins, consistent with HPV gene expression and the onset of neoplasia in both live and fixed samples. Principle component analysis was used to objectively discriminate between the cells types giving sensitivities up to 100% for the comparison between PHK and CaSki. These results show that Raman spectroscopy can discriminate between cell lines representing different stages of cervical neoplasia. Furthermore Raman spectroscopy was able to identify cells expressing the HPV 16 E7 gene suggesting the approach may be of value in clinical practice. Finally this technique was also able to detect the effects of the virus in fixed samples demonstrating the compatibility of this technique with current cervical screening methods. However if Raman spectroscopy is to make a significant impact in clinical practice the long acquisition times must be addressed. In this report we examine the potential for beam shaping and advanced to improve the signal to noise ration hence subsequently facilitating a reduction in acquisition time.

  6. Advanced Instrumentation and Control Methods for Small and Medium Reactors with IRIS Demonstration

    SciTech Connect

    J. Wesley Hines; Belle R. Upadhyaya; J. Michael Doster; Robert M. Edwards; Kenneth D. Lewis; Paul Turinsky; Jamie Coble

    2011-05-31

    Development and deployment of small-scale nuclear power reactors and their maintenance, monitoring, and control are part of the mission under the Small Modular Reactor (SMR) program. The objectives of this NERI-consortium research project are to investigate, develop, and validate advanced methods for sensing, controlling, monitoring, diagnosis, and prognosis of these reactors, and to demonstrate the methods with application to one of the proposed integral pressurized water reactors (IPWR). For this project, the IPWR design by Westinghouse, the International Reactor Secure and Innovative (IRIS), has been used to demonstrate the techniques developed under this project. The research focuses on three topical areas with the following objectives. Objective 1 - Develop and apply simulation capabilities and sensitivity/uncertainty analysis methods to address sensor deployment analysis and small grid stability issues. Objective 2 - Develop and test an autonomous and fault-tolerant control architecture and apply to the IRIS system and an experimental flow control loop, with extensions to multiple reactor modules, nuclear desalination, and optimal sensor placement strategy. Objective 3 - Develop and test an integrated monitoring, diagnosis, and prognosis system for SMRs using the IRIS as a test platform, and integrate process and equipment monitoring (PEM) and process and equipment prognostics (PEP) toolboxes. The research tasks are focused on meeting the unique needs of reactors that may be deployed to remote locations or to developing countries with limited support infrastructure. These applications will require smaller, robust reactor designs with advanced technologies for sensors, instrumentation, and control. An excellent overview of SMRs is described in an article by Ingersoll (2009). The article refers to these as deliberately small reactors. Most of these have modular characteristics, with multiple units deployed at the same plant site. Additionally, the topics focus

  7. Opportunity Rolls Free Again (Right Front Wheel)

    NASA Technical Reports Server (NTRS)

    2006-01-01

    This animated piece illustrates the recent escape of NASA's Mars Exploration Rover Opportunity from dangerous, loose material on the vast plains leading to the rover's next long-term target, 'Victoria Crater.'

    A series of images of the rover's right front wheel, taken by the front hazard-avoidance camera, make up this brief movie. It chronicles the challenge Opportunity faced to free itself from a ripple dubbed 'Jammerbugt.' The rover's wheels became partially embedded in the ripple at the end of a drive on Opportunity's 833rd Martian day, or sol (May 28, 2006). The images in this clip were taken on sols 836 through 841 (May 31 through June 5, 2006).

    Scientists and engineers who had been elated at the meters of progress the rover had been making in earlier drives were happy for even centimeters of advance per sol as they maneuvered their explorer through the slippery material of Jammerbugt. The wheels reached solid footing on a rock outcrop on the final sol of this sequence.

    The science and engineering teams appropriately chose the ripple's informal from name the name of a bay on the north coast of Denmark. Jammerbugt, or Jammerbugten, loosely translated, means Bay of Lamentation or Bay of Wailing. The shipping route from the North Sea to the Baltic passes Jammerbugt on its way around the northern tip of Jutland. This has always been an important trade route and many ships still pass by the bay. The prevailing wind directions are typically northwest to southwest with the strongest winds and storms tending to blow from the northwest. A northwesterly wind will blow straight into the Jammerbugt, towards shore. Therefore, in the age of sail, many ships sank there during storms. The shore is sandy, but can have strong waves, so running aground was very dangerous even though there are no rocks.

    Fortunately, Opportunity weathered its 'Jammerbugt' and is again on its way toward Victoria Crater.

  8. Opportunity Rolls Free Again (Left Front Wheel)

    NASA Technical Reports Server (NTRS)

    2006-01-01

    This animated piece illustrates the recent escape of NASA's Mars Exploration Rover Opportunity from dangerous, loose material on the vast plains leading to the rover's next long-term target, 'Victoria Crater.'

    A series of images of the rover's left front wheel, taken by the front hazard-avoidance camera, make up this brief movie. It chronicles the challenge Opportunity faced to free itself from a ripple dubbed 'Jammerbugt.' The rover's wheels became partially embedded in the ripple at the end of a drive on Opportunity's 833rd Martian day, or sol (May 28, 2006). The images in this clip were taken on sols 836 through 841 (May 31 through June 5, 2006).

    Scientists and engineers who had been elated at the meters of progress the rover had been making in earlier drives were happy for even centimeters of advance per sol as they maneuvered their explorer through the slippery material of Jammerbugt. The wheels reached solid footing on a rock outcrop on the final sol of this sequence.

    The science and engineering teams appropriately chose the ripple's informal from name the name of a bay on the north coast of Denmark. Jammerbugt, or Jammerbugten, loosely translated, means Bay of Lamentation or Bay of Wailing. The shipping route from the North Sea to the Baltic passes Jammerbugt on its way around the northern tip of Jutland. This has always been an important trade route and many ships still pass by the bay. The prevailing wind directions are typically northwest to southwest with the strongest winds and storms tending to blow from the northwest. A northwesterly wind will blow straight into the Jammerbugt, towards shore. Therefore, in the age of sail, many ships sank there during storms. The shore is sandy, but can have strong waves, so running aground was very dangerous even though there are no rocks.

    Fortunately, Opportunity weathered its 'Jammerbugt' and is again on its way toward Victoria Crater.

  9. Light-Front Holography, Light-Front Wavefunctions, and Novel QCD Phenomena

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.; /Costa Rica U.

    2012-02-16

    momentum distributions. The effective confining potential also creates quark-antiquark pairs from the amplitude q {yields} q{bar q}q. Thus in holographic QCD higher Fock states can have any number of extra q{bar q} pairs. We discuss the relevance of higher Fock-states for describing the detailed structure of space and time-like form factors. The AdS/QCD model can be systematically improved by using its complete orthonormal solutions to diagonalize the full QCD light-front Hamiltonian or by applying the Lippmann-Schwinger method in order to systematically include the QCD interaction terms. A new perspective on quark and gluon condensates is also obtained.

  10. Front surface structured targets for enhancing laser-plasma interactions

    NASA Astrophysics Data System (ADS)

    Snyder, Joseph; George, Kevin; Ji, Liangliang; Yalamanchili, Sasir; Simonoff, Ethan; Cochran, Ginevra; Daskalova, Rebecca; Poole, Patrick; Willis, Christopher; Lewis, Nathan; Schumacher, Douglass

    2016-10-01

    We present recent progress made using front surface structured interfaces for enhancing ultrashort, relativistic laser-plasma interactions. Structured targets can increase laser absorption and enhance ion acceleration through a number of mechanisms such as direct laser acceleration and laser guiding. We detail experimental results obtained at the Scarlet laser facility on hollow, micron-scale plasma channels for enhancing electron acceleration. These targets show a greater than three times enhancement in the electron cutoff energy as well as an increased slope temperature for the electron distribution when compared to a flat interface. Using three-dimensional particle-in-cell (PIC) simulations, we have modeled the interaction to give insight into the physical processes responsible for the enhancement. Furthermore, we have used PIC simulations to design structures that are more advantageous for ion acceleration. Such targets necessitate advanced target fabrication methods and we describe techniques used to manufacture optimized structures, including vapor-liquid-solid growth, cryogenic etching, and 3D printing using two-photon-polymerization. This material is based upon work supported by the Air Force Office of Scientific Research under Award Number FA9550-14-1-0085.

  11. Analyzing Planck and low redshift data sets with advanced statistical methods

    NASA Astrophysics Data System (ADS)

    Eifler, Tim

    The recent ESA/NASA Planck mission has provided a key data set to constrain cosmology that is most sensitive to physics of the early Universe, such as inflation and primordial NonGaussianity (Planck 2015 results XIII). In combination with cosmological probes of the LargeScale Structure (LSS), the Planck data set is a powerful source of information to investigate late time phenomena (Planck 2015 results XIV), e.g. the accelerated expansion of the Universe, the impact of baryonic physics on the growth of structure, and the alignment of galaxies in their dark matter halos. It is the main objective of this proposal to re-analyze the archival Planck data, 1) with different, more recently developed statistical methods for cosmological parameter inference, and 2) to combine Planck and ground-based observations in an innovative way. We will make the corresponding analysis framework publicly available and believe that it will set a new standard for future CMB-LSS analyses. Advanced statistical methods, such as the Gibbs sampler (Jewell et al 2004, Wandelt et al 2004) have been critical in the analysis of Planck data. More recently, Approximate Bayesian Computation (ABC, see Weyant et al 2012, Akeret et al 2015, Ishida et al 2015, for cosmological applications) has matured to an interesting tool in cosmological likelihood analyses. It circumvents several assumptions that enter the standard Planck (and most LSS) likelihood analyses, most importantly, the assumption that the functional form of the likelihood of the CMB observables is a multivariate Gaussian. Beyond applying new statistical methods to Planck data in order to cross-check and validate existing constraints, we plan to combine Planck and DES data in a new and innovative way and run multi-probe likelihood analyses of CMB and LSS observables. The complexity of multiprobe likelihood analyses scale (non-linearly) with the level of correlations amongst the individual probes that are included. For the multi

  12. Advanced Spectral Analysis Methods for Quantification of Coherent Ultrasound Scattering: Applications in the Breast

    NASA Astrophysics Data System (ADS)

    Rosado-Mendez, Ivan M.

    The goal of this dissertation was to improve the diagnostic value of parametric images generated from Quantitative Ultrasound (QUS) methods based on the power spectral density (PSD) of radiofrequency echo signals. This was achieved by testing for local adherence to conventional QUS assumptions that echo signals originate from incoherent scattering, and that signals are stationary over PSD estimation windows. For this purpose, we designed a novel algorithm that empirically evaluates the statistical significance of coherent-scattering signatures in the echo signals. Signatures are quantified through a set of optimized metrics describing the stationary or non-stationary features of the echo signals. We compared Nakagami-model based metrics and model-free metrics of the statistics of the echo signal amplitude for analyzing stationary features. For non-stationary features, we advanced the use of the echo-signal generalized spectrum by comparing single- and multi-taper estimators of this spectrum to the time-domain singular spectrum analysis method. Tests of statistical significance were done through empirical comparisons with values of the same metrics estimated from a uniform reference material exhibiting incoherent scattering. The metrics that quantify these features were selected after simulation- and phantom-based optimizations centered on the task of creating parametric images, where tradeoffs must be made between spatial resolution and detection performance. The connection of the analyses of the stationary and the non-stationary features provided a way to estimate descriptors of the tissue organization scales below and above the resolution limit imposed by the size of the acoustic pulse. A preliminary application of the developed algorithm was done on echo data from human breast lesions scanned in vivo. Results supported the idea of a more homogeneously random distribution of subresolution scatterers within invasive ductal carcinomas than within fibroadenomas

  13. FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance, part 2

    NASA Technical Reports Server (NTRS)

    Harris, Charles E. (Editor)

    1994-01-01

    The international technical experts in the areas of durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The principal focus of the symposium was on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on the following topics: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and corrosion resistance.

  14. IFA - INTELLIGENT FRONT ANNOTATION PROGRAM

    NASA Technical Reports Server (NTRS)

    Burke, G. R.

    1994-01-01

    An important aspect of an ASIC (Application Specific Integrated Circuit) design process is verification. The design must not only be functionally accurate, but it must also maintain the correct timing. After a circuit has been laid out, one can utilize the Back Annotation (BA) method to simulate the design and obtain an accurate estimate of performance. However, this can lead to major design changes. It is therefore preferable to eliminate potential problems early in this process. IFA, the Intelligent Front Annotation program, assists in verifying the timing of the ASIC early in the design process. Many difficulties can arise during ASIC design. In a synchronous design, both long path and short path problems can be present. In modern ASIC technologies, the delay through a gate is very dependent on loading. This loading has two main components, the capacitance of the gates being driven and the capacitance of the metal tracks (wires). When using GaAs gate arrays, the metal line capacitance is often the dominating factor. Additionally, the RC delay through the wire itself is significant in sub-micron technologies. Since the wire lengths are unknown before place and route of the entire chip, this would seem to postpone any realistic timing verification until towards the end of the design process, obviously an undesirable situation. The IFA program estimates the delays in an ASIC before layout. Currently the program is designed for Vitesse GaAs gate arrays and, for input, requires the expansion file which is output by the program GED; however, the algorithm is appropriate for many different ASIC types and CAE platforms. IFA is especially useful for devices whose delay is extremely dependent on the interconnection wiring. It estimates the length of the interconnects using information supplied by the user and information in the netlist. The resulting wire lengths are also used to constrain the Place and Route program, ensuring reasonable results. IFA takes locality into

  15. Ion acceleration in dipolarization fronts

    NASA Astrophysics Data System (ADS)

    Birn, J.; Hesse, M.

    2014-12-01

    The electric field associated with flow bursts and dipolarization fronts has been shown to be an efficient mechanism for producing energetic ions and electrons. Using an MHD simulation of magnetotail reconnection, flow bursts and dipolarization, we investigate the acceleration of test particles to suprathermal energies. Particular emphasis of this presentation is on spatial, temporal, and angular variations of the modeled energetic ion fluxes. The test particle simulations reproduce characteristic features of observed injection events, such as a fast rise of energetic particle fluxes, limitations in energy, and demonstrate the large variability of energetic ion features.

  16. Crystallization and saturation front propagation in silicic magma chambers

    NASA Astrophysics Data System (ADS)

    Lake, Ethan T.

    2013-12-01

    The cooling and crystallization style of silicic magma bodies in the upper crust falls on a continuum between whole-chamber processes of convection, crystal settling, and cumulate formation and interface-driven processes of conduction and crystallization front migration. In the end-member case of vigorous convection and crystal settling, volatile saturation advances downward from the roof and upward from the floor throughout the chamber. In the end-member case of stagnant magma bodies, volatile saturation occurs along an inward propagating front from all sides of the chamber. Ambient thermal gradient primarily controls the propagation rate; warm (⩾40 °C/km) geothermal gradients lead to thick (1200+ m) crystal mush zones and slow crystallization front propagation. Cold (<40 °C/km) geothermal gradients lead to rapid crystallization front propagation and thin (<1000 m) mush zones. Magma chamber geometry also exerts a first-order control on propagation rates; bodies with high surface to magma volume ratio and large Earth-surface-parallel faces exhibit more rapid propagation and thinner mush zones. Crystallization front propagation occurs at speeds of greater than 10 cm/yr (rhyolitic magma; 1 km thick sill geometry in a 20 °C/km geotherm), far faster than diffusion of volatiles in magma and faster than bubbles can nucleate, grow, and ascend through the chamber. Numerical simulations indicate saturation front propagation is determined primarily by pressure and magma crystallization rate; above certain initial water contents (4.4 wt.% in a dacite) the mobile magma is volatile-rich enough above 10 km depth to always contains a saturation front. Saturation fronts propagate down from the magma chamber roof at lower water contents (3.3 wt.% in a dacite at 5 km depth), creating an upper saturated interface for most common (4-6 wt.%) magma water contents. This upper interface promotes the production of a fluid pocket underneath the apex of the magma chamber. If the fluid

  17. Unstructured mesh methods for CFD

    NASA Technical Reports Server (NTRS)

    Peraire, J.; Morgan, K.; Peiro, J.

    1990-01-01

    Mesh generation methods for Computational Fluid Dynamics (CFD) are outlined. Geometric modeling is discussed. An advancing front method is described. Flow past a two engine Falcon aeroplane is studied. An algorithm and associated data structure called the alternating digital tree, which efficiently solves the geometric searching problem is described. The computation of an initial approximation to the steady state solution of a given poblem is described. Mesh generation for transient flows is described.

  18. Monitoring of infrastructural sites by means of advanced multi-temporal DInSAR methods

    NASA Astrophysics Data System (ADS)

    Vollrath, Andreas; Zucca, Francesco; Stramondo, Salvatore

    2013-10-01

    With the launch of Sentinel-1, advanced interferometric measurements will become more applicable then ever. The foreseen standard Wide Area Product (WAP), with its higher spatial and temporal resolution than comparable SAR missions, will provide the basement for the use of new wide scale and multitemporal analysis. By now the use of SAR interferometry methods with respect to risk assessment are mainly conducted for active tectonic zones, plate boundaries, volcanoes as well as urban areas, where local surface movement rates exceed the expected error and enough pixels per area contain a relatively stable phase. This study, in contrast, aims to focus on infrastructural sites that are located outside cities and are therefore surrounded by rural landscapes. The stumbling bock was given by the communication letter by the European Commission with regard to the stress tests of nuclear power plants in Europe in 2012. It is mentioned that continuously re-evaluated risk and safety assessments are necessary to guarantee highest possible security to the European citizens and environment. This is also true for other infrastructural sites, that are prone to diverse geophysical hazards. In combination with GPS and broadband seismology, multitemporal Differential Interferometric SAR approaches demonstrated great potential in contributing valuable information to surface movement phenomenas. At this stage of the project, first results of the Stamps-MTI approach (combined PSInSAR and SBAS) will be presented for the industrial area around Priolo Gargallo in South East Sicily by using ENVISAT ASAR IM mode data from 2003-2010. This area is located between the Malta Escarpment fault system and the Hyblean plateau and is prone to earthquake and tsunami risk. It features a high density of oil refineries that are directly located at the coast. The general potential of these techniques with respect to the SENTINEL-1 mission will be shown for this area and a road-map for further improvements

  19. 1. VIEW SOUTHWARD FROM SOUTHWEST CORNER FRONT AND ARCH STREETS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW SOUTHWARD FROM SOUTHWEST CORNER FRONT AND ARCH STREETS (2. N. Front Street starts at left) - North Front Street Area Study, 2-66 North Front Street (Commercial Buildings), Philadelphia, Philadelphia County, PA

  20. Double-Front Detonation Waves

    NASA Astrophysics Data System (ADS)

    Gubin, S. A.; Sumskoi, S. I.; Victorov, S. B.

    According to the theory of detonation, in a detonation wave there is a sound plane, named Chapman-Jouguet (CJ) plane. There are certain stationary parameters for this plane. In this work the possibility of the second CJ plane is shown. This second CJ plane is stationary as well. The physical mechanism of non-equilibrium transition providing the existence of the second CJ plane is presented. There is a non-equilibrium state, when the heat is removed from the reaction zone and the heat capacity decreases sharply. As a result of this non-equilibrium state, the sound velocity increases, and the local supersonic zone with second sonic plane (second CJ plane) appears. So the new mode of detonation wave is predicted. Equations describing this mode of detonation are presented. The exact analytical solution for the second CJ plane parameters is obtained. The example of double-front detonation in high explosive (TNT) is presented. In this double-front structure "nanodiamond-nanographite" phase transition takes place in condensed particles of detonation products.

  1. Fast and accurate 3-D ray tracing using bilinear traveltime interpolation and the wave front group marching

    NASA Astrophysics Data System (ADS)

    Zhang, Jianzhong; Huang, Yueqin; Song, Lin-Ping; Liu, Qing-Huo

    2011-03-01

    We propose a new ray tracing technique in a 3-D heterogeneous isotropic media based on bilinear traveltime interpolation and the wave front group marching. In this technique, the media is discretized into a series of rectangular cells. There are two steps to be carried out: one is a forward step where wave front expansion is evolved from sources to whole computational domain and the subsequent one is a backward step where ray paths are calculated for any source-receiver configuration as desired. In the forward step, we derive a closed-form expression to calculate traveltime at an arbitrary point in a cell using a bilinear interpolation of the known traveltimes on the cell's surface. Then the group marching method (GMM), a fast wave front advancing method, is applied to expand the wave front from the source to all girds. In the backward step, ray paths starting from receivers are traced by finding the intersection points of potential ray propagation vectors with the surfaces of relevant cells. In this step, the same TI scheme is used to compute the candidate intersection points on all surfaces of each relevant cell. In this process, the point with the minimum traveltime is selected as a ray point from which the similar step is continued until sources. A number of numerical experiments demonstrate that our 3-D ray tracing technique is able to achieve very accurate computation of traveltimes and ray paths and meanwhile take much less computer time in comparison with the existing popular ones like the finite-difference-based GMM method, which is combined with the maximum gradient ray tracing, and the shortest path method.

  2. Advanced fire-resistant forms of activated carbon and methods of adsorbing and separating gases using same

    SciTech Connect

    Xiong, Yongliang; Wang, Yifeng

    2015-02-03

    Advanced, fire-resistant activated carbon compositions useful in adsorbing gases; and having vastly improved fire resistance are provided, and methods for synthesizing the compositions are also provided. The advanced compositions have high gas adsorption capacities and rapid adsorption kinetics (comparable to commercially-available activated carbon), without having any intrinsic fire hazard. They also have superior performance to Mordenites in both adsorption capacities and kinetics. In addition, the advanced compositions do not pose the fibrous inhalation hazard that exists with use of Mordenites. The fire-resistant compositions combine activated carbon mixed with one or more hydrated and/or carbonate-containing minerals that release H.sub.2O and/or CO.sub.2 when heated. This effect raises the spontaneous ignition temperature to over 500.degree. C. in most examples, and over 800.degree. C. in some examples. Also provided are methods for removing and/or separating target gases, such as Krypton or Argon, from a gas stream by using such advanced activated carbons.

  3. [Research advances and applications of the methods to repair mandible defect].

    PubMed

    Yuan, Yuan-jie; Weng, Yu-lai; Cao, Yi-lin

    2004-04-01

    Mandible defects can be caused by many diseases, most commonly occurring in cranio-maxillofacial regions. With the development of orthopaedics, biomaterial and cell biology in these years, great improvements have been acquired in repair of mandible defects. This paper systematically reviewed the relevant research advances and applications, and showed the applied prospect of bone tissue engineering in this field.

  4. Investigating the Limitations of Advanced Design Methods through Real World Application

    DTIC Science & Technology

    2016-03-31

    of Aerospace Engineering Doc ID#: 116361 Aerospace Systems Design Laboratory (ASDL) 275 Ferst Drive Atlanta, GA 30332-0150 9. SPONSORING I...SUPPLEMENTARY NOTES 14. ABSTRACT This final report details the results of the partnership between the Aerospace Systems Design Laboratory (ASDL) at the...architectures. 1S. SUBJECT TERMS Naval Engineering, Advanced Systems Design , Modeling & Simulation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION

  5. Optimization of advanced Wiener estimation methods for Raman reconstruction from narrow-band measurements in the presence of fluorescence background.

    PubMed

    Chen, Shuo; Ong, Yi Hong; Lin, Xiaoqian; Liu, Quan

    2015-07-01

    Raman spectroscopy has shown great potential in biomedical applications. However, intrinsically weak Raman signals cause slow data acquisition especially in Raman imaging. This problem can be overcome by narrow-band Raman imaging followed by spectral reconstruction. Our previous study has shown that Raman spectra free of fluorescence background can be reconstructed from narrow-band Raman measurements using traditional Wiener estimation. However, fluorescence-free Raman spectra are only available from those sophisticated Raman setups capable of fluorescence suppression. The reconstruction of Raman spectra with fluorescence background from narrow-band measurements is much more challenging due to the significant variation in fluorescence background. In this study, two advanced Wiener estimation methods, i.e. modified Wiener estimation and sequential weighted Wiener estimation, were optimized to achieve this goal. Both spontaneous Raman spectra and surface enhanced Raman spectra were evaluated. Compared with traditional Wiener estimation, two advanced methods showed significant improvement in the reconstruction of spontaneous Raman spectra. However, traditional Wiener estimation can work as effectively as the advanced methods for SERS spectra but much faster. The wise selection of these methods would enable accurate Raman reconstruction in a simple Raman setup without the function of fluorescence suppression for fast Raman imaging.

  6. Effects of mechanical dispersion on the morphological evolution of a chemical dissolution front in a fluid-saturated porous medium

    NASA Astrophysics Data System (ADS)

    Chen, Jui-Sheng; Liu, Chen-Wuing; Lai, Geng-Xin; Ni, Chuen-Fa

    2009-06-01

    SummaryThe dissolution-induced finger or wormhole patterns in porous medium or fracture rock play a crucial role in a variety of scientific, industrial, and engineering practices. Although previous studies have extensively presented a number of numerical models which couples a system of nonlinear governing equations of porosity change due to mineral dissolution, the conservations of groundwater flow and transport of chemical species to investigate the morphological pattern of a chemical dissolution front within a fluid-saturated porous medium, whereas the mechanical dispersion effect has generally been neglected in the model development. This study addresses the effects of mechanical dispersion on the morphological evolution of a chemical dissolution front for a variety of cases. Mechanical dispersion processes is incorporated with the coupled nonlinear governing equation system so as to rebuild a newly numerical model. The results of numerical simulations demonstrate that mechanical dispersion has pronounced impacts on the morphological pattern of the chemical dissolution front. For single local non-uniformity case, mechanical dispersion reduces the finger length of an unstable single-fingering front or retains the shape of a stable planar front while speeding up the front advancement. In the case of two local non-uniformities, adding mechanical dispersion with different flow conditions can yield one of the following results: (1) the shape of the stable planar front is maintained but its advancement is accelerated; (2) the shape of the unstable single-fingering front is maintained but its length is reduced; (3) the unstable double-fingering front is merged into an unstable single-fingering front; and (4) the shape of the unstable double-fingering front is preserved but its fingering length is reduced. A comparison between the behavior diagrams of dissolution front morphology (with and without considering mechanical dispersion) shows that the double-fingering front

  7. Scaling of Quench Front and Entrainment-Related Phenomena

    SciTech Connect

    Aumiller, D. L.; Hourser, R. J.; Holowach, M. J.; Hochreiter, L. E.; Cheung, F-B.

    2002-04-01

    The scaling of thermal hydraulic systems is of great importance in the development of experiments in laboratory-scale test facilities that are used to replicate the response of full-size prototypical designs. One particular phenomenon that is of interest in experimental modeling is the quench front that develops during the reflood phase in a PWR (Pressurized Water Reactor) following a large-break LOCA (Loss of Coolant Accident). The purpose of this study is to develop a scaling methodology such that the prototypical quench front related phenomena can be preserved in a laboratory-scale test facility which may have material, geometrical, fluid, and flow differences as compared to the prototypical case. A mass and energy balance on a Lagrangian quench front control volume along with temporal scaling methods are utilized in developing the quench front scaling groups for a phenomena-specific second-tier scaling analysis. A sample calculation is presented comparing the quench front scaling groups calculated for a prototypical Westinghouse 17 x 17 PWR fuel design and that of the geometry and material configuration used in the FLECHT SEASET series of experiments.

  8. Instability of coupled geostrophic density fronts and its nonlinear evolution

    NASA Astrophysics Data System (ADS)

    Scherer, Emilie; Zeitlin, Vladimir

    Instability of coupled density fronts, and its fully nonlinear evolution are studied within the idealized reduced-gravity rotating shallow-water model. By using the collocation method, we benchmark the classical stability results on zero potential vorticity (PV) fronts and generalize them to non-zero PV fronts. In both cases, we find a series of instability zones intertwined with the stability regions along the along-front wavenumber axis, the most unstable modes being long wave. We then study the nonlinear evolution of the unstable modes with the help of a high-resolution well-balanced finite-volume numerical scheme by initializing it with the unstable modes found from the linear stability analysis. The most unstable long-wave mode evolves as follows: after a couple of inertial periods, the coupled fronts are pinched at some location and a series of weakly connected co-rotating elliptic anticyclonic vortices is formed, thus totally changing the character of the flow. The characteristics of these vortices are close to known rodon lens solutions. The shorter-wave unstable modes from the next instability zones are strongly concentrated in the frontal regions, have sharp gradients, and are saturated owing to dissipation without qualitatively changing the flow pattern.

  9. Advances in a framework to compare bio-dosimetry methods for triage in large-scale radiation events

    PubMed Central

    Flood, Ann Barry; Boyle, Holly K.; Du, Gaixin; Demidenko, Eugene; Nicolalde, Roberto J.; Williams, Benjamin B.; Swartz, Harold M.

    2014-01-01

    Planning and preparation for a large-scale nuclear event would be advanced by assessing the applicability of potentially available bio-dosimetry methods. Using an updated comparative framework the performance of six bio-dosimetry methods was compared for five different population sizes (100–1 000 000) and two rates for initiating processing of the marker (15 or 15 000 people per hour) with four additional time windows. These updated factors are extrinsic to the bio-dosimetry methods themselves but have direct effects on each method's ability to begin processing individuals and the size of the population that can be accommodated. The results indicate that increased population size, along with severely compromised infrastructure, increases the time needed to triage, which decreases the usefulness of many time intensive dosimetry methods. This framework and model for evaluating bio-dosimetry provides important information for policy-makers and response planners to facilitate evaluation of each method and should advance coordination of these methods into effective triage plans. PMID:24729594

  10. Condensation Front Migration in a Protoplanetary Nebula

    NASA Technical Reports Server (NTRS)

    Davis, Sanford S.

    2004-01-01

    Condensation front dynamics are investigated in the mid-solar nebula region. A quasi-steady model of the evolving nebula is combined with equilibrium vapor pressure curves to determine evolutionary condensation fronts for selected species. These fronts are found to migrate inwards from the far-nebula to final positions during a period of 10(exp 7) years. The physical process governing this movement is a combination of local viscous heating and luminescent heating from the central star. Two luminescent heating models are used and their effects on the ultimate radial position of the condensation front are discussed. At first the fronts move much faster than the nebular accretion velocity, but after a time the accreting gas and dust overtakes the slowing condensation front.

  11. Advances in the p and h-p Versions of the Finite Element Method. A survey

    DTIC Science & Technology

    1988-01-01

    ORGANIZATION 14AME ANO ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK AREA & WORK UNIT NMBGERS Institute for Physical Science and Technology University of Maryland... Institute for Physical Science and Technology( University of Maryland, College Park, MD 20742 ABSTRACT. The paper gives the survey of the advances in the...p versions is the code PROBE which was developed by NOETIC Technologies, St. Louis, MO [49] [60]. PROBE solves two dimensional problems of linear

  12. Distribution transformer performance when subjected to steep front impulses

    SciTech Connect

    Burrage, L.M.; Shaw, J.H. . Thomas A. Edison Technical Center); McConnell, B.W. )

    1990-04-01

    The experimental method and the results of subjecting arrester protected pole type distribution transformers to the combined stresses caused by the conducted steep front impulse and rated 60 Hz voltages are described. Comparisons are drawn between these results and those of similar experiments on unenergized distribution transformers. It is concluded that tank mounted direct connected arresters provide a high degree of protection to these transformers, tank mounted externally gapped or crossarm mounted arresters may not provide sufficient protection; internal transformer insulation system failures caused by the steep front impulse do not necessarily result in immediate catastrophic failures of the transformers.

  13. Use of advanced particle methods in modeling space propulsion and its supersonic expansions

    NASA Astrophysics Data System (ADS)

    Borner, Arnaud

    This research discusses the use of advanced kinetic particle methods such as Molecular Dynamics (MD) and direct simulation Monte Carlo (DSMC) to model space propulsion systems such as electrospray thrusters and their supersonic expansions. MD simulations are performed to model an electrospray thruster for the ionic liquid (IL) EMIM--BF4 using coarse-grained (CG) potentials. The model is initially featuring a constant electric field applied in the longitudinal direction. Two coarse-grained potentials are compared, and the effective-force CG (EFCG) potential is found to predict the formation of the Taylor cone, the cone-jet, and other extrusion modes for similar electric fields and mass flow rates observed in experiments of a IL fed capillary-tip-extractor system better than the simple CG potential. Later, one-dimensional and fully transient three-dimensional electric fields, the latter solving Poisson's equation to take into account the electric field due to space charge at each timestep, are computed by coupling the MD model to a Poisson solver. It is found that the inhomogeneous electric field as well as that of the IL space-charge improve agreement between modeling and experiment. The boundary conditions (BCs) are found to have a substantial impact on the potential and electric field, and the tip BC is introduced and compared to the two previous BCs, named plate and needle, showing good improvement by reducing unrealistically high radial electric fields generated in the vicinity of the capillary tip. The influence of the different boundary condition models on charged species currents as a function of the mass flow rate is studied, and it is found that a constant electric field model gives similar agreement to the more rigorous and computationally expensive tip boundary condition at lower flow rates. However, at higher mass flow rates the MD simulations with the constant electric field produces extruded particles with higher Coulomb energy per ion, consistent with

  14. DSD front models: nonideal explosive detonation in ANFO

    SciTech Connect

    Bdzil, J. B.; Aslam, T. D.; Catanach, R. A.; Hill, L. G.; Short, M.

    2002-01-01

    The DSD method for modeling propagating detonation is based on three elements: (1) a subscale theory of multi-dimensional detonation that treats the detonation as a front whose dynamics depends only on metrics of the front (such as curvature, etc.), (2) high-resolution, direct numerical simulation of detonation using Euler equation models, and (3) physical experiments to characterize multi-dimensional detonation propagation in real explosives and to provide data to calibrate DSD front models. In this paper, we describe our work on elements (1) and (3), develop a DSD calibration for the nonideal explosive ANFO and then demonstrate the utility of the ANFO calibration, with an example 3D detonation propagation calculation.

  15. Tomographic wave-front sensing with a single guide star

    NASA Astrophysics Data System (ADS)

    Hart, Michael; Jefferies, Stuart; Hope, Douglas

    2016-09-01

    Adaptive optics or numerical restoration algorithms that restore high resolution imaging through atmospheric turbulence are subject to isoplanatic wave-front errors. Mitigating those errors requires that the wave-front aberrations be estimated within the 3D volume of the atmosphere. Present techniques rely on multiple beacons, either natural stars or laser guide stars, to probe the atmospheric aberration along different lines of sight, followed by tomographic projection of the measurements onto layers at defined ranges. In this paper we show that a three-dimensional estimate of the wave-front aberration can be recovered from measurements by a single guide star in the case where the aberration is stratified, provided that the telescope tracks across the sky with non-uniform angular velocity. This is generally the case for observations of artificial earth-orbiting satellites, and the new method is likely to find application in ground-based telescopes used for space situational awareness.

  16. Measurement of the shock front velocity produced in a T-tube

    SciTech Connect

    Djurović, S.; Mijatović, Z.; Vujičić, B.; Kobilarov, R.; Savić, I.; Gavanski, L.

    2015-01-15

    A set of shock front velocity measurements is described in this paper. The shock waves were produced in a small electromagnetically driven shock T-tube. Most of the measurements were performed in hydrogen. The shock front velocity measurements in other gases and the velocity of the gas behind the shock front were also analyzed, as well as the velocity dependence on applied input energy. Some measurements with an applied external magnetic field were also performed. The used method of shock front velocity is simple and was shown to be very reliable. Measured values were compared with the calculated ones for the incident and reflected shock waves.

  17. Asymptotic analysis of reaction-diffusion-advection problems: Fronts with periodic motion and blow-up

    NASA Astrophysics Data System (ADS)

    Nefedov, Nikolay

    2017-02-01

    This is an extended variant of the paper presented at MURPHYS-HSFS 2016 conference in Barcelona. We discuss further development of the asymptotic method of differential inequalities to investigate existence and stability of sharp internal layers (fronts) for nonlinear singularly perturbed periodic parabolic problems and initial boundary value problems with blow-up of fronts for reaction-diffusion-advection equations. In particular, we consider periodic solutions with internal layer in the case of balanced reaction. For the initial boundary value problems we prove the existence of fronts and give their asymptotic approximation including the new case of blowing-up fronts. This case we illustrate by the generalised Burgers equation.

  18. A linear phase retrieval wave-front sensor

    NASA Astrophysics Data System (ADS)

    Li, Min; Li, Xin-Yang; Jiang, Wen-Han

    2008-12-01

    A method to retrieve small phase aberration from a single far-field image is proposed. It only needs to calibrate the inherent aberration of the imaging system once, and then the difference between a single measured image with aberration and the calibrated image with inherent aberration is got to retrieve the disturbed phase aberration by an approximate linear relationship. Computer simulations are employed to analyze the performance of this linear phase retrieval (LPR) wave-front sensor. The dynamic range of this method is discussed without noise to judge how small it is needed to satisfy the method. The results show that the proposed small phase retrieval method works well when the RMS phase error is less than 1.6 rad. The Linear Phase Retrieval wave-front sensor and the Hartmann-Shack wave-front sensor are compared on the same stochastic wave-front aberration. The influence of different calculation condition on the retrieval results is compared and analyzed. After analyzing the target resolution, it is thought that a reasonable target size is advantageous to the retrieval precision. At the same time, the LPR sensor can realize the alike precision measurement by using less detect cell, such as 8 pixelx8 pixel in our experiment. From the retrieval results of different orders, the error rate are less than 0.25 and it is comparatively accurate to retrieve pre-35 order aberrations.

  19. Wave front distortion based fluid flow imaging

    NASA Astrophysics Data System (ADS)

    Iffa, Emishaw; Heidrich, Wolfgang

    2013-03-01

    In this paper, a transparent flow surface reconstruction based on wave front distortion is investigated. A camera lens is used to focus the image formed by the micro-lens array to the camera imaging plane. The irradiance of the captured image is transformed to frequency spectrum and then the x and y spatial components are separated. A rigid spatial translation followed by low pass filtering yields a single frequency component of the image intensity. Index of refraction is estimated from the inverse Fourier transform of the spatial frequency spectrum of the irradiance. The proposed method is evaluated with synthetic data of a randomly generated index of refraction value and used to visualize a fuel injection volumetric data.

  20. A Model For Teaching Advanced Neuroscience Methods: A Student-Run Seminar to Increase Practical Understanding and Confidence

    PubMed Central

    Harrison, Theresa M.; Ching, Christopher R. K.; Andrews, Anne M.

    2016-01-01

    Neuroscience doctoral students must master specific laboratory techniques and approaches to complete their thesis work (hands-on learning). Due to the highly interdisciplinary nature of the field, learning about a diverse range of methodologies through literature surveys and coursework is also necessary for student success (hands-off learning). Traditional neuroscience coursework stresses what is known about the nervous system with relatively little emphasis on the details of the methods used to obtain this knowledge. Furthermore, hands-off learning is made difficult by a lack of detail in methods sections of primary articles, subfield-specific jargon and vague experimental rationales. We designed a student-taught course to enable first-year neuroscience doctoral students to overcome difficulties in hands-off learning by introducing a new approach to reading and presenting primary research articles that focuses on methodology. In our literature-based course students were encouraged to present a method with which they had no previous experience. To facilitate weekly discussions, “experts” were invited to class sessions. Experts were advanced graduate students who had hands-on experience with the method being covered and served as discussion co-leaders. Self-evaluation worksheets were administered on the first and last days of the 10-week course and used to assess students’ confidence in discussing research and methods outside of their primary research expertise. These evaluations revealed that the course significantly increased the students’ confidence in reading, presenting and discussing a wide range of advanced neuroscience methods. PMID:27980464

  1. A Model For Teaching Advanced Neuroscience Methods: A Student-Run Seminar to Increase Practical Understanding and Confidence.

    PubMed

    Harrison, Theresa M; Ching, Christopher R K; Andrews, Anne M

    2016-01-01

    Neuroscience doctoral students must master specific laboratory techniques and approaches to complete their thesis work (hands-on learning). Due to the highly interdisciplinary nature of the field, learning about a diverse range of methodologies through literature surveys and coursework is also necessary for student success (hands-off learning). Traditional neuroscience coursework stresses what is known about the nervous system with relatively little emphasis on the details of the methods used to obtain this knowledge. Furthermore, hands-off learning is made difficult by a lack of detail in methods sections of primary articles, subfield-specific jargon and vague experimental rationales. We designed a student-taught course to enable first-year neuroscience doctoral students to overcome difficulties in hands-off learning by introducing a new approach to reading and presenting primary research articles that focuses on methodology. In our literature-based course students were encouraged to present a method with which they had no previous experience. To facilitate weekly discussions, "experts" were invited to class sessions. Experts were advanced graduate students who had hands-on experience with the method being covered and served as discussion co-leaders. Self-evaluation worksheets were administered on the first and last days of the 10-week course and used to assess students' confidence in discussing research and methods outside of their primary research expertise. These evaluations revealed that the course significantly increased the students' confidence in reading, presenting and discussing a wide range of advanced neuroscience methods.

  2. Light-Front Holography and Non-Perturbative QCD

    SciTech Connect

    Brodsky, Stanley J.; de Teramond, Guy F.; /Costa Rica U.

    2009-12-09

    The combination of Anti-de Sitter space (AdS) methods with light-front holography leads to a semi-classical first approximation to the spectrum and wavefunctions of meson and baryon light-quark bound states. Starting from the bound-state Hamiltonian equation of motion in QCD, we derive relativistic light-front wave equations in terms of an invariant impact variable {zeta} which measures the separation of the quark and gluonic constituents within the hadron at equal light-front time. These equations of motion in physical space-time are equivalent to the equations of motion which describe the propagation of spin-J modes in anti-de Sitter (AdS) space. Its eigenvalues give the hadronic spectrum, and its eigenmodes represent the probability distribution of the hadronic constituents at a given scale. Applications to the light meson and baryon spectra are presented. The predicted meson spectrum has a string-theory Regge form M{sup 2} = 4{kappa}{sup 2}(n + L + S = 2); i.e., the square of the eigenmass is linear in both L and n, where n counts the number of nodes of the wavefunction in the radial variable {zeta}. The space-like pion form factor is also well reproduced. One thus obtains a remarkable connection between the description of hadronic modes in AdS space and the Hamiltonian formulation of QCD in physical space-time quantized on the light-front at fixed light-front time {tau}. The model can be systematically improved by using its complete orthonormal solutions to diagonalize the full QCD light-front Hamiltonian or by applying the Lippmann-Schwinger method in order to systematically include the QCD interaction terms.

  3. ADVANCED METHODS FOR THE COMPUTATION OF PARTICLE BEAM TRANSPORT AND THE COMPUTATION OF ELECTROMAGNETIC FIELDS AND MULTIPARTICLE PHENOMENA

    SciTech Connect

    Alex J. Dragt

    2012-08-31

    Since 1980, under the grant DEFG02-96ER40949, the Department of Energy has supported the educational and research work of the University of Maryland Dynamical Systems and Accelerator Theory (DSAT) Group. The primary focus of this educational/research group has been on the computation and analysis of charged-particle beam transport using Lie algebraic methods, and on advanced methods for the computation of electromagnetic fields and multiparticle phenomena. This Final Report summarizes the accomplishments of the DSAT Group from its inception in 1980 through its end in 2011.

  4. Extraction, Analytical and Advanced Methods for Detection of Allura Red AC (E129) in Food and Beverages Products

    PubMed Central

    Rovina, Kobun; Siddiquee, Shafiquzzaman; Shaarani, Sharifudin M.

    2016-01-01

    Allura Red AC (E129) is an azo dye that widely used in drinks, juices, bakery, meat, and sweets products. High consumption of Allura Red has claimed an adverse effects of human health including allergies, food intolerance, cancer, multiple sclerosis, attention deficit hyperactivity disorder, brain damage, nausea, cardiac disease and asthma due to the reaction of aromatic azo compounds (R = R′ = aromatic). Several countries have banned and strictly controlled the uses of Allura Red in food and beverage products. This review paper is critically summarized on the available analytical and advanced methods for determination of Allura Red and also concisely discussed on the acceptable daily intake, toxicology and extraction methods. PMID:27303385

  5. Development of advanced modal methods for calculating transient thermal and structural response

    NASA Technical Reports Server (NTRS)

    Camarda, Charles J.

    1991-01-01

    Higher-order modal methods for predicting thermal and structural response are evaluated. More accurate methods or ones which can significantly reduce the size of complex, transient thermal and structural problems are desirable for analysis and are required for synthesis of real structures subjected to thermal and mechanical loading. A unified method is presented for deriving successively higher-order modal solutions related to previously-developed, lower-order methods such as the mode displacement and mode-acceleration methods. A new method, called the force-derivative method, is used to obtain higher-order modal solutions for both uncoupled (proportionally-damped) structural problems as well as thermal problems and coupled (non-proportionally damped) structural problems. The new method is called the force-derivative method because, analogous to the mode-acceleration method, it produces a term that depends on the forcing function and additional terms that depend on the time derivatives of the forcing function.

  6. Advances in coupled safety modeling using systems analysis and high-fidelity methods.

    SciTech Connect

    Fanning, T. H.; Thomas, J. W.; Nuclear Engineering Division

    2010-05-31

    The potential for a sodium-cooled fast reactor to survive severe accident initiators with no damage has been demonstrated through whole-plant testing in EBR-II and FFTF. Analysis of the observed natural protective mechanisms suggests that they would be characteristic of a broad range of sodium-cooled fast reactors utilizing metal fuel. However, in order to demonstrate the degree to which new, advanced sodium-cooled fast reactor designs will possess these desired safety features, accurate, high-fidelity, whole-plant dynamics safety simulations will be required. One of the objectives of the advanced safety-modeling component of the Reactor IPSC is to develop a science-based advanced safety simulation capability by utilizing existing safety simulation tools coupled with emerging high-fidelity modeling capabilities in a multi-resolution approach. As part of this integration, an existing whole-plant systems analysis code has been coupled with a high-fidelity computational fluid dynamics code to assess the impact of high-fidelity simulations on safety-related performance. With the coupled capabilities, it is possible to identify critical safety-related phenomenon in advanced reactor designs that cannot be resolved with existing tools. In this report, the impact of coupling is demonstrated by evaluating the conditions of outlet plenum thermal stratification during a protected loss of flow transient. Outlet plenum stratification was anticipated to alter core temperatures and flows predicted during natural circulation conditions. This effect was observed during the simulations. What was not anticipated, however, is the far-reaching impact that resolving thermal stratification has on the whole plant. The high temperatures predicted at the IHX inlet due to thermal stratification in the outlet plenum forces heat into the intermediate system to the point that it eventually becomes a source of heat for the primary system. The results also suggest that flow stagnation in the

  7. Observation of subsonic and supersonic radiation fronts on OMEGA utilizing radiation transport through Sc-doped aerogels

    NASA Astrophysics Data System (ADS)

    Johns, H. M.; Kline, J.; Lanier, N.; Perry, T.; Fontes, C.; Fryer, C.; Brown, C.; Morton, J.; Hager, J.

    2016-10-01

    The propagation of a heat front in an astrophysical or inertial confinement fusion plasma involves both the equation of state and the opacity of the plasma, and is therefore an important and challenging radiation transport problem. Past experiments have used absorption spectroscopy in chlorinated foams to measure the heat front. (D. Hoarty et al. PRL 82, 3070, 1999). Recent development of Ti-doped cylindrical aerogel foam targets (J. Hager et al. submitted to RSI) results in a more suitable platform for higher temperatures on NIF than Cl dopant. Ti K-shell absorption spectra can be modeled with PrismSPECT to obtain spatially resolved temperature profiles between 100-180eV. Sc dopant has been selected to characterize the heat front between 60-100eV. Improved understanding of non-planckian x-ray drives generated by hohlraums will advance characterization of the radiation transport. Prior work demonstrates PrismSPECT with OPLIB is more physically complete for Sc (H. Johns et al. submitted to RSI). We will present the first application of spectroscopic analysis of the Sc-doped aerogels utilizing this method. This work performed under the auspices of the U.S. Department of Energy by LANL under contract DE-AC52-06NA25396.

  8. Advanced Durability and Damage Tolerance Design and Analysis Methods for Composite Structures: Lessons Learned from NASA Technology Development Programs

    NASA Technical Reports Server (NTRS)

    Harris, Charles E.; Starnes, James H., Jr.; Shuart, Mark J.

    2003-01-01

    Aerospace vehicles are designed to be durable and damage tolerant. Durability is largely an economic life-cycle design consideration whereas damage tolerance directly addresses the structural airworthiness (safety) of the vehicle. However, both durability and damage tolerance design methodologies must address the deleterious effects of changes in material properties and the initiation and growth of microstructural damage that may occur during the service lifetime of the vehicle. Durability and damage tolerance design and certification requirements are addressed for commercial transport aircraft and NASA manned spacecraft systems. The state-of-the-art in advanced design and analysis methods is illustrated by discussing the results of several recently completed NASA technology development programs. These programs include the NASA Advanced Subsonic Technology Program demonstrating technologies for large transport aircraft and the X-33 hypersonic test vehicle demonstrating technologies for a single-stage-to-orbit space launch vehicle.

  9. Recent advances quantifying the large wood dynamics in river basins: New methods and remaining challenges

    NASA Astrophysics Data System (ADS)

    Ruiz-Villanueva, Virginia; Piégay, Hervé; Gurnell, Angela A.; Marston, Richard A.; Stoffel, Markus

    2016-09-01

    Large wood is an important physical component of woodland rivers and significantly influences river morphology. It is also a key component of stream ecosystems. However, large wood is also a source of risk for human activities as it may damage infrastructure, block river channels, and induce flooding. Therefore, the analysis and quantification of large wood and its mobility are crucial for understanding and managing wood in rivers. As the amount of large-wood-related studies by researchers, river managers, and stakeholders increases, documentation of commonly used and newly available techniques and their effectiveness has also become increasingly relevant as well. Important data and knowledge have been obtained from the application of very different approaches and have generated a significant body of valuable information representative of different environments. This review brings a comprehensive qualitative and quantitative summary of recent advances regarding the different processes involved in large wood dynamics in fluvial systems including wood budgeting and wood mechanics. First, some key definitions and concepts are introduced. Second, advances in quantifying large wood dynamics are reviewed; in particular, how measurements and modeling can be combined to integrate our understanding of how large wood moves through and is retained within river systems. Throughout, we present a quantitative and integrated meta-analysis compiled from different studies and geographical regions. Finally, we conclude by highlighting areas of particular research importance and their likely future trajectories, and we consider a particularly underresearched area so as to stress the future challenges for large wood research.

  10. A Streamline-Upwind Model for Filling Front Advection in Powder Injection Moulding

    NASA Astrophysics Data System (ADS)

    Larsen, Guillaume; Cheng, Zhi Qiang; Barriere, Thierry; Liu, Bao Sheng; Gelin, Jean-Claude

    2010-06-01

    The filling process of powder injection molding is modeled by the flows of two variably adjacent domains in the mold cavity. The feedstock is filled into the cavity while the air is expelled out by the injected feedstock [1]. Eulerian description is adopted. The filling patterns are determined by the solution of an advection equation, governed by the velocity field in both the feedstock flow and air flow [2]. In the real physics, the advance of filling front depends mainly on the flow of feedstock that locates behind the front. The flow of air in front of the injected material plays in fact no meaningful effect. However, the actual algorithm for solution of the advection equation takes equally the importance for both the flow of viscous feedstock and that of the slight air. Under such a condition, the injection flow of feedstock in simulation may be misdirected unrealistically by the velocity field in the air portion of the mold cavity. To correct this defect, an upwind scheme is proposed to reinforce the effect of upwind flow and reduce the effect of downstream flow. The present paper involves the investigation of an upwind algorithm for simulation of the filling state during powder injection molding. A Petrov-Galerkin upwind based method (SUPG) is adopted for numerical simulation of the transport equation instead of the Taylor-Galerkin method in previous work. In the proposed implementation of the Streamline-Upwind/Petrov-Galerkin (SUPG) approach. A stabilization method is used to prevent oscillations in the convection-dominated problems. It consists in the introduction of an artificial diffusion in streamline direction. Suitable modification of the test function is the important issue. It ensures the stable simulation of filling process and results in the more realistic prediction of filling patterns. The implementation of upwind scheme in mould filling state simulation, based on an advection equation and the whole velocity field of feedstock and air flow, makes

  11. [Research advances on DNA extraction methods from peripheral blood mononuclear cells].

    PubMed

    Wang, Xiao-Ying; Yu, Chen-Xi

    2014-10-01

    DNA extraction is a basic technology of molecular biology. The purity and the integrality of DNA structure are necessary for different experiments of gene engineering. As commonly used materials in the clinical detection, the fast, efficient isolation and extraction of genomic DNA from peripheral blood mononuclear cells is very important for the inspection and analysis of clinical blood. At present, there are many methods for extracting DNA, such as phenol-chloroform method, salting out method, centrifugal adsorption column chromatography method (artificial methods), magnetic beads (semi-automatic method) and DNA extraction kit. In this article, a brief review of the principle for existing DNA blood extraction method, the specific steps and the assessment of the specific methods briefly are summarized.

  12. The Role of Front-Back Features in Children's 'Front', 'Back', and 'Beside' Placements of Objects.

    ERIC Educational Resources Information Center

    Harris, Lauren; Strommen, Ellen

    1970-01-01

    In a study of spatial orientation, 40 boys and 40 girls from kindergarten and first grade placed a series of objects in front, behind, and beside themselves, and in front, behind, and beside other objects. Some objects had distinguishable front and back sides; others lacked such features. Placements were highly consistent within and across…

  13. Light-front holographic QCD and emerging confinement

    SciTech Connect

    Brodsky, Stanley J.; de Téramond, Guy F.; Dosch, Hans Günter; Erlich, Joshua

    2015-05-21

    In this study we explore the remarkable connections between light-front dynamics, its holographic mapping to gravity in a higher-dimensional anti-de Sitter (AdS) space, and conformal quantum mechanics. This approach provides new insights into the origin of a fundamental mass scale and the physics underlying confinement dynamics in QCD in the limit of massless quarks. The result is a relativistic light-front wave equation for arbitrary spin with an effective confinement potential derived from a conformal action and its embedding in AdS space. This equation allows for the computation of essential features of hadron spectra in terms of a single scale. The light-front holographic methods described here give a precise interpretation of holographic variables and quantities in AdS space in terms of light-front variables and quantum numbers. This leads to a relation between the AdS wave functions and the boost-invariant light-front wave functions describing the internal structure of hadronic bound-states in physical spacetime. The pion is massless in the chiral limit and the excitation spectra of relativistic light-quark meson and baryon bound states lie on linear Regge trajectories with identical slopes in the radial and orbital quantum numbers. In the light-front holographic approach described here currents are expressed as an infinite sum of poles, and form factors as a product of poles. At large q2 the form factor incorporates the correct power-law fall-off for hard scattering independent of the specific dynamics and is dictated by the twist. At low q2 the form factor leads to vector dominance. The approach is also extended to include small quark masses. We briefly review in this report other holographic approaches to QCD, in particular top-down and bottom-up models based on chiral symmetry breaking. We also include a discussion of open problems and future applications.

  14. Advanced stability indicating chemometric methods for quantitation of amlodipine and atorvastatin in their quinary mixture with acidic degradation products

    NASA Astrophysics Data System (ADS)

    Darwish, Hany W.; Hassan, Said A.; Salem, Maissa Y.; El-Zeany, Badr A.

    2016-02-01

    Two advanced, accurate and precise chemometric methods are developed for the simultaneous determination of amlodipine besylate (AML) and atorvastatin calcium (ATV) in the presence of their acidic degradation products in tablet dosage forms. The first method was Partial Least Squares (PLS-1) and the second was Artificial Neural Networks (ANN). PLS was compared to ANN models with and without variable selection procedure (genetic algorithm (GA)). For proper analysis, a 5-factor 5-level experimental design was established resulting in 25 mixtures containing different ratios of the interfering species. Fifteen mixtures were used as calibration set and the other ten mixtures were used as validation set to validate the prediction ability of the suggested models. The proposed methods were successfully applied to the analysis of pharmaceutical tablets containing AML and ATV. The methods indicated the ability of the mentioned models to solve the highly overlapped spectra of the quinary mixture, yet using inexpensive and easy to handle instruments like the UV-VIS spectrophotometer.

  15. Numerical study of a mesoscale vortex in the planetary boundary layer of the meiyu front

    NASA Astrophysics Data System (ADS)

    Shen, Hangfeng; Zhai, Guoqing; Zhu, Ye; Xu, Yaqin

    2012-12-01

    It was found that the heavy rainfall event along the Meiyu front in the lower reaches of the Yangtze River on 23 June 2009 was connected with a mesoscale disturbance vortex, which originated from the planetary boundary layer (PBL) and developed upward later and was discovered by using the Shuman-Shapiro filtering method. The mesoscale disturbance vortex in the PBL (PMDV) in this process corresponded well to the short-time rainstorm in the Doppler radar echo. Analysis of the high-resolution simulation results from the Advanced Weather Research and Forecasting Model (ARW) showed that there were several surface disturbances along the southern warm section of the Meiyu front prior to the generation of the PMDV. The PMDV interacted with the mesoscale convective system (MCS) and intensified the local convective precipitation. The north and southwest flows in the PBL converged at the time of the PMDV formation. Meanwhile, a southwesterly jet on the top of the PBL to the south side of the vortex reinforced the ascending motion and convergence. Hence, it is concluded that the PMDV was generated when the strong cold air flows north of the shear line encountered the southwest flow south of the shear line. The convergence line in the PBL, the intensification of the southwest wind, and the southward aggression of the north wind were critical for the development of the PMDV. The release of latent heat was found crucial for the formation of the PMDV as it facilitated the convergence at low levels.

  16. Effects of fluctuations on propagating fronts

    NASA Astrophysics Data System (ADS)

    Panja, Debabrata

    Propagating fronts are seen in varieties of nonequilibrium pattern forming systems in Physics, Chemistry and Biology. In the last two decades, many researchers have contributed to the understanding of the underlying dynamics of the propagating fronts. Of these, the deterministic and mean-field dynamics of the fronts were mostly understood in late 1980s and 1990s. On the other hand, although the earliest work on the effect of fluctuations on propagating fronts dates back to early 1980s, the subject of fluctuating fronts did not reach its adolescence until the mid 1990s. From there onwards the last few years witnessed a surge in activities in the effect of fluctuations on propagating fronts. Scores of papers have been written on this subject since then, contributing to a significant maturity of our understanding, and only recently a full picture of fluctuating fronts has started to emerge. This review is an attempt to collect all the works on fluctuating (propagating) fronts in a coherent and cogent manner in proper perspective. It is based on the idea of making our knowledge in this field available to a broader audience, and it is also expected to help to collect bits and pieces of loose thread-ends together for possible further investigation.

  17. Propagation of Sinusoidally-Corrugated Shock Fronts of Laser-Supported Detonations

    NASA Astrophysics Data System (ADS)

    Honda, T.; Kawaguchi, A.; Hanta, Y.; Susa, A.; Namba, S.; Johzaki, T.; Endo, T.; Shiraga, H.; Shigemori, K.; Koga, M.; Nagatomo, H.

    The behavior of sinusoidally-rippled shock fronts is a fundamental research topic in the dynamics of shock waves [1]. The Whitham's ray-shock theory, which is sometimes called the geometrical-shock-dynamics (GSD) theory, is known as a simple method for analyzing the behavior of a non-planar shock front. In this theory, narrow ray tubes corresponding to the light rays in the geometrical optics are placed perpendicularly to the every portions of a non-planar shock front, and the evolution of the shock front is calculated by tracking the shock front in each ray tube sequentially. When the behavior of an inert sinusoidally-rippled shock front is analyzed by the GSD theory and the Chester-Chisnell-Whitham's (CCW's) A-M relationship [2], where A is the cross-sectional area of a ray tube and M is the propagation Mach number of the shock wave in the ray tube, the amplitude of the shock-front ripple oscillates as the shock wave propagates [3]. Actually, the behavior of an inert sinusoidally-rippled shock front is influenced by the fluid motion in the shock-compressed region, and the amplitude of the shock-front ripple shows damped oscillation as the shock wave propagates [1,3,4,5].

  18. Studying electric fields in dipolarization fronts

    NASA Astrophysics Data System (ADS)

    Balcerak, Ernie

    2014-11-01

    In Earth's magnetotail, sharp increases in the magnetic field known as dipolarization fronts are associated with high-speed plasma flows that connect Earth's ionosphere via electric currents. Some aspects of these dipolarization fronts have puzzled scientists; in particular, the dip in magnetic field that occurs just ahead of the dipolarization front layer is not well understood. Sun et al. analyze observations made using the Cluster satellites to elucidate the details of electric fields associated with dipolarization fronts. The study shows that a type of electric current known as a Hall current dominates in the dipolarization front region and in the region where the magnetic field dips, but this current flows in opposite directions in these two regions.

  19. Recent advances in methods for numerical solution of O.D.E. initial value problems

    NASA Technical Reports Server (NTRS)

    Bui, T. D.; Oppenheim, A. K.; Pratt, D. T.

    1984-01-01

    In the mathematical modeling of physical systems, it is often necessary to solve an initial value problem (IVP), consisting of a system of ordinary differential equations (ODE). A typical program produces approximate solutions at certain mesh points. Almost all existing codes try to control the local truncation error, while the user is really interested in controlling the true or global error. The present investigation provides a review of recent advances regarding the solution of the IVP, giving particular attention to stiff systems. Stiff phenomena are customarily defined in terms of the eigenvalues of the Jacobian. There are, however, some difficulties connected with this approach. It is pointed out that an estimate of the Lipschitz constant proves to be a very practical way to determine the stiffness of a problem.

  20. Systematic review of novel ablative methods in locally advanced pancreatic cancer.

    PubMed

    Keane, Margaret G; Bramis, Konstantinos; Pereira, Stephen P; Fusai, Giuseppe K

    2014-03-07

    Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis. Current standard therapy is limited to chemotherapy or chemoradiotherapy. Few regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently needed. Thermal and laser based ablative techniques are widely used in many solid organ malignancies. Initial studies in the pancreas were associated with significant morbidity and mortality, which limited widespread adoption. Modifications to the various applications, in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in safety. We conducted a systematic review of the literature up to October 2013. Initial studies suggest that ablative therapies may confer an additional survival benefit over best supportive care but randomised studies are required to validate these findings.

  1. Optimization of engines for a commercial Mach 0.98 transport using advanced turbine cooling methods

    NASA Technical Reports Server (NTRS)

    Kraft, G. A.; Whitlow, J. B., Jr.

    1972-01-01

    A study was made of an advanced technology airplane using supercritical aerodynamics. Cruise Mach number was 0.98 at 40,000 feet altitude with a payload of 60,000 pounds and a range of 3000 nautical miles. Separate-flow turbofans were examined parametrically to determine the effect of sea-level-static design turbine-inlet-temperature and noise on takeoff gross weight (TOGW) assuming full-film turbine cooling. The optimum turbine inlet temperature was 2650 F. Two-stage-fan engines, with cruise fan pressure ratio of 2.25, achieved a noise goal of 103.5 EPNdB with todays noise technology while one-stage-fan engines, achieved a noise goal of 98 EPNdB. The take-off gross weight penalty to use the one-stage fan was 6.2 percent.

  2. On the multimodality of preparative TREF fractionation as detected by advanced analytical methods.

    PubMed

    Ndiripo, Anthony; Pasch, Harald

    2015-08-01

    Preparative temperature rising elution fractionation (prepTREF) is the standard technique for the preparative fractionation of polyolefins according to crystallisability. For olefin copolymers such as linear low-density polyethylene (LLDPE), it was believed that the TREF elution temperature correlates directly with the copolymer composition. For copolymers having different bulk comonomer contents, the prepTREF fractions of different samples collected at a given temperature were assumed to have the same chemical composition. It was acknowledged quite early that co-crystallisation effects may disturb TREF fractionation and fractions are obtained that are not completely homogeneous. This, however, has not been investigated quantitatively so far. The fundamental statement of prepTREF is challenged for the first time quantitatively using advanced analytical techniques including high-temperature high-performance liquid chromatography (HPLC). Ethylene-1-octene copolymers having bulk comonomer contents ranging from 0.3 to 6.4 mol% were fractionated by prepTREF, and the fractions were analysed by high-temperature size exclusion chromatography, crystallisation analysis fractionation, differential scanning calorimetry and high-temperature HPLC. All analytical results prove that the TREF fractions collected from different samples at the same elution temperature have different chemical compositions. The chemical compositions of the fractions correlate with the compositions of the bulk samples in that the comonomer contents of similar TREF fractions increase with an increase of the comonomer content of the bulk samples. These results are in clear contrast to the previous assumption that the TREF fraction composition is independent of the bulk copolymer composition for a given copolymer type. Graphical abstract Advanced analysis of LLDPE by combination of HT-HPLC, DSC and CRYSTAF.

  3. OPTIMA: advanced methods for the analysis, integration, and optimization of PRISMA mission products

    NASA Astrophysics Data System (ADS)

    Guzzi, Donatella; Pippi, Ivan; Aiazzi, Bruno; Baronti, Stefano; Carlà, Roberto; Lastri, Cinzia; Nardino, Vanni; Raimondi, Valentina; Santurri, Leonardo; Selva, Massimo; Alparone, Luciano; Garzelli, Andrea; Lopinto, Ettore; Ananasso, Cristina; Barducci, Alessandro

    2015-10-01

    PRISMA is an Earth observation system that combines a hyperspectral sensor with a panchromatic, medium-resolution camera. OPTIMA is one of the five independent scientific research projects funded by the Italian Space Agency in the framework of PRISMA mission for the development of added-value algorithms and advanced applications. The main goal of OPTIMA is to increase and to strengthen the applications of PRISMA through the implementation of advanced methodologies for the analysis, integration and optimization of level 1 and 2 products. The project is comprehensive of several working packages: data simulation, data quality, data optimization, data processing and integration and, finally, evaluation of some applications related to natural hazards. Several algorithms implemented during the project employ high-speed autonomous procedures for the elaboration of the upcoming images acquired by PRISMA. To assess the performances of the developed algorithms and products, an end-to-end simulator of the instrument has been implemented. Data quality analysis has been completed by introducing noise modeling. Stand-alone procedures of radiometric and atmospheric corrections have been developed, allowing the retrieval of at-ground spectral reflectance maps. Specific studies about image enhancement, restoration and pan-sharpening have been carried out for providing added-value data. Regarding the mission capability of monitoring environmental processes and disasters, different techniques for estimating surface humidity and for analyzing burned areas have been investigated. Finally, calibration and validation activities utilizing the CAL/VAL test site managed by CNR-IFAC and located inside the Regional Park of San Rossore (Pisa), Italy have been considered.

  4. Development and comparison of advanced reduced-basis methods for the transient structural analysis of unconstrained structures

    NASA Technical Reports Server (NTRS)

    Mcgowan, David M.; Bostic, Susan W.; Camarda, Charles J.

    1993-01-01

    The development of two advanced reduced-basis methods, the force derivative method and the Lanczos method, and two widely used modal methods, the mode displacement method and the mode acceleration method, for transient structural analysis of unconstrained structures is presented. Two example structural problems are studied: an undamped, unconstrained beam subject to a uniformly distributed load which varies as a sinusoidal function of time and an undamped high-speed civil transport aircraft subject to a normal wing tip load which varies as a sinusoidal function of time. These example problems are used to verify the methods and to compare the relative effectiveness of each of the four reduced-basis methods for performing transient structural analyses on unconstrained structures. The methods are verified with a solution obtained by integrating directly the full system of equations of motion, and they are compared using the number of basis vectors required to obtain a desired level of accuracy and the associated computational times as comparison criteria.

  5. Interaction of a cold front with a sea-breeze front Observations

    NASA Astrophysics Data System (ADS)

    Brümmer, B.; Hennemuth, B.; Rhodin, A.; Thiemann, S.

    1995-08-01

    On 9 May 1989, during the field experiment FRONTEX, a synoptic-scale cold front was observed which moved from the North Sea to Northern Germany and interacted with a sea-breeze front. The modification of the cold front is documented by satellite images and measurements over the sea, at the coast and further inland. The synoptic-scale front was characterized by weak frontal gradients over the sea. It was aligned approximately parallel to the coast as was approximately the wind ahead of it. While the synoptic-scale front approached the coast during the forenoon hours, a strong temperature contrast developed between sea and land due to solar heating of the land surface. This led to the formation of a sea-breeze front associated with a stronger temperature gradient than the synoptic-scale front. At about noon, when the synoptic-scale front almost reached the coast, the sea-breeze front began to move inland. The onshore wind behind the sea-breeze front and ahead of the synoptic-scale front was so large that the wind field at the synoptic-scale front changed from confluence to difluence. This process was supported by a shallow inversion ahead of the synoptic-scale front which confined the vertical depth of the sea-breeze. The former sea-breeze front overtook the main frontal characteristics, continued its inland propagation and was the only frontal event observed over the land. As a result of the interaction, the synoptic-scale front was significantly intensified in the boundary layer.

  6. Onshore propagation of a buoyant ocean front observed using a shore-based marine radar

    NASA Astrophysics Data System (ADS)

    Marmorino, G. O.; Cooper, A. L.; Mied, R. P.; Lindemann, G. J.; Trizna, D. B.; Porter, D. L.

    2004-06-01

    An analysis is presented of a 2-h-long time series of X-band marine radar images, collected at Duck, North Carolina (USA), that captured the evolution of a buoyant ocean front as it propagated onshore, following a period of upwelling-favorable winds. In plan view, the front exhibits a scallop-shaped structure similar to that previously observed along strongly convergent fronts. This alongshore structure consists of broad frontal crests (a few hundred meters in length) alternating with sharply angled troughs, or frontal cusps. The evolution of these frontal shapes is explored using a reduced-gravity model (Cooper et al., J. Geophys. Res.-Oceans 106 (2001) 16887) that allows for nonlinear self-interaction of a propagating front. A model simulation shows cusps that develop quickly from initially broad troughs and that point toward the buoyant water, features resembling the observations. However, the simulation also shows a continuous oscillation of frontal shapes, while the observed front reaches a quasi-steady plan form. We attribute this difference in behavior to the gradual shoaling of the observed front as it steadily advances, ultimately reaching water depths of less than 2 m, which is comparable to the thickness of the buoyant layer. As a consequence of the shoaling, we suggest the cusps become sites of enhanced mixing, where water inshore of the front is also accelerated seaward.

  7. Multiscale Design of Advanced Materials based on Hybrid Ab Initio and Quasicontinuum Methods

    SciTech Connect

    Luskin, Mitchell

    2014-03-12

    This project united researchers from mathematics, chemistry, computer science, and engineering for the development of new multiscale methods for the design of materials. Our approach was highly interdisciplinary, but it had two unifying themes: first, we utilized modern mathematical ideas about change-of-scale and state-of-the-art numerical analysis to develop computational methods and codes to solve real multiscale problems of DOE interest; and, second, we took very seriously the need for quantum mechanics-based atomistic forces, and based our methods on fast solvers of chemically accurate methods.

  8. Method for compression molding of thermosetting plastics utilizing a temperature gradient across the plastic to cure the article

    NASA Technical Reports Server (NTRS)

    Heier, W. C. (Inventor)

    1974-01-01

    A method is described for compression molding of thermosetting plastics composition. Heat is applied to the compressed load in a mold cavity and adjusted to hold molding temperature at the interface of the cavity surface and the compressed compound to produce a thermal front. This thermal front advances into the evacuated compound at mean right angles to the compression load and toward a thermal fence formed at the opposite surface of the compressed compound.

  9. A Life Cycle Assessment of a Magnesium Automotive Front End

    SciTech Connect

    Das, Sujit; Dubreuil, Alain; Bushi, Lindita; Tharumarajah, Ambalavanar

    2009-01-01

    The Magnesium Front End Research and Development (MFERD) project under the sponsorship of Canada, China and USA aims to develop key technologies and a knowledge base for increased use of magnesium in automobile. The goal of this life cycle assessment (LCA) study is to compare the energy and potential environmental impacts of advanced magnesium based front end parts of a North America built 2007 GM-Cadillac CTS with the standard carbon steel based design. This LCA uses the 'cradle-to-grave' approach by including primary material production, semi-fabrication production, autoparts manufacturing and assembly, transportation, use phase and end-of-life processing of autoparts. This LCA study was done in compliance with international standards ISO 14040:2006 and ISO 14044:2006. Furthermore, the LCA results for aluminum based front end autopart are presented. While weight savings result in reductions in energy use and carbon dioxide emissions during the use of the car, the impacts of fabrication and recycling of lightweight materials are substantial in regard to steel. Pathways for improving sustainability of magnesium use in automobiles through material management and technology improvements including recycling are also discussed.

  10. Experiments and simulations of RT and RM fronts

    NASA Astrophysics Data System (ADS)

    Lopez, P.; Gushkov, S.

    2009-04-01

    Experimental and numerical results on the advance of a mixing or non-mixing front occurring at a density interface due to gravitational acceleration are analyzed considering the fractal and spectral structure of the front. The experimental configuration consists on a unstable two layer system held by a removable plate in a box for the Rayleigh-Taylor fronts and shock tube high Mach number impulse across a density interface air/SF6. The evolution of the turbulent mixing layer and its complex configuration is studied taking into account the dependence on the initial modes at the early stages and its spectral, self-similar information. Most models of the turbulent mixing evolution generated by hydrodynamics instabilities do not include any dependence on initial conditions, but in many relevant physical problems this dependence is very important, for instance, in Inertial Confinement Fussion target implosion. We discuss simple initial conditions (such as a jet array versus a plate removal) with the aid of numerical models. The analysis of Kelvin-Helmholtz, Rayleigh-Taylor, Richtmyer-Meshkov and of accelerated instabilities is presented locally, and seen to dominate the turbulent cascade mixing zone differently under different initial conditions. Fractal and neuron network analysis of Turbulent Mixing under RT and RM instabilities are presented comparing the different experiments and numerical simulations.

  11. ADVANCING REACTIVE TRACER METHODS FOR MONITORING THERMAL DRAWDOWN IN GEOTHERMAL ENHANCED GEOTHERMAL RESERVOIRS

    SciTech Connect

    Mitchell A. Plummer; Carl D. Palmer; Earl D. Mattson; George D. Redden; Laurence C. Hull

    2010-10-01

    Reactive tracers have long been considered a possible means of measuring thermal drawdown in a geothermal system, before significant cooling occurs at the extraction well. Here, we examine the sensitivity of the proposed method to evaluate reservoir cooling and demonstrate that while the sensitivity of the method as generally proposed is low, it may be practical under certain conditions.

  12. Advances in the Use of Neuroscience Methods in Research on Learning and Instruction

    ERIC Educational Resources Information Center

    De Smedt, Bert

    2014-01-01

    Cognitive neuroscience offers a series of tools and methodologies that allow researchers in the field of learning and instruction to complement and extend the knowledge they have accumulated through decades of behavioral research. The appropriateness of these methods depends on the research question at hand. Cognitive neuroscience methods allow…

  13. New Advances in the Trojan Horse Method as an Indirect Approach to Nuclear Astrophysics

    NASA Astrophysics Data System (ADS)

    Tumino, A.; Spitaleri, C.; Cherubini, S.; Gulino, M.; La Cognata, M.; Lamia, L.; Pizzone, R. G.; Puglia, S. M. R.; Rapisarda, G. G.; Romano, S.; Sergi, M. L.; Spartà, R.

    2013-05-01

    With the introduction of the Trojan Horse Method, nuclear cross sections between charged particles at astrophysical energies can now be measured. Here the basic features of the method are recalled together with recent results relevant for Nuclear Astrophysics. New applications in connection with plasma physics and industrial energy production are discussed.

  14. Recent advances in methods and techniques for freshness quality determination and evaluation of fish and fish fillets: a review.

    PubMed

    Cheng, Jun-Hu; Sun, Da-Wen; Zeng, Xin-An; Liu, Dan

    2015-01-01

    The freshness quality of fish plays an important role in human health and the acceptance of consumers as well as in international fishery trade. Recently, with food safety becoming a critical issue of great concern in the world, determination and evaluation of fish freshness is much more significant in research and development. This review renovates and concentrates recent advances of evaluating methods for fish freshness as affected by preharvest and postharvest factors and highlights the determination methods for fish freshness including sensory evaluation, microbial inspection, chemical measurements of moisture content, volatile compounds, protein changes, lipid oxidation, and adenosine triphosphate (ATP) decomposition (K value), physical measurements, and foreign material contamination detection. Moreover, the advantages and disadvantages of these methods and techniques are compared and discussed and some viewpoints about the current work and future trends are also presented.

  15. Acidity Constant (pKa ) Calculation of Large Solvated Dye Molecules: Evaluation of Two Advanced Molecular Dynamics Methods.

    PubMed

    De Meyer, Thierry; Ensing, Bernd; Rogge, Sven M J; De Clerck, Karen; Meijer, Evert Jan; Van Speybroeck, Veronique

    2016-11-04

    pH-Sensitive dyes are increasingly applied on polymer substrates for the creation of novel sensor materials. Recently, these dye molecules were modified to form a covalent bond with the polymer host. This had a large influence on the pH-sensitive properties, in particular on the acidity constant (pKa ). Obtaining molecular control over the factors that influence the pKa value is mandatory for the future intelligent design of sensor materials. Herein, we show that advanced molecular dynamics (MD) methods have reached the level at which the pKa values of large solvated dye molecules can be predicted with high accuracy. Two MD methods were used in this work: steered or restrained MD and the insertion/deletion scheme. Both were first calibrated on a set of phenol derivatives and afterwards applied to the dye molecule bromothymol blue. Excellent agreement with experimental values was obtained, which opens perspectives for using these methods for designing dye molecules.

  16. Advanced Numerical Methods for Computing Statistical Quantities of Interest from Solutions of SPDES

    DTIC Science & Technology

    2012-01-19

    and tested our method. Figure 1 presents a comparison of the solution of (5) obtained by a Monte- Carlo method and that of (6) using a stochastic...2 0 .3 0 .4 0.4 0.4 0.5 0 .5 0 .6 0 .6 0.6 0.6 0 .7 0.70 .7 0 .8 0.8 0 .9 x y Isotherms, Monte Carlo method, number of samples=200 0 0.2 0.4 0.6 0.8 0...of the solution of (5) obtained by a Monte- Carlo method (top) and that of (6) using a stochastic collocation method with fewer samples (bottom

  17. Advanced methods for light trapping in optically thin silicon solar cells

    NASA Astrophysics Data System (ADS)

    Nagel, James Richard

    2011-12-01

    The field of light trapping is the study of how best to absorb light in a thin film of material when most light either reflects away at the surface or transmits straight through to the other side. This has tremendous application to the field of photovoltaics where thin silicon films can be manufactured cheaply, but also fail to capture all of the available photons in the solar spectrum. Advancements in light trapping therefore bring us closer to the day when photovoltaic devices may reach grid parity with traditional fossil fuels on the electrical energy market. This dissertation advances our understanding of light trapping by first modeling the effects of loss in planar dielectric waveguides. The mathematical framework developed here can be used to model any arbitrary three-layer structure with mixed gain or loss and then extract the total field solution for the guided modes. It is found that lossy waveguides possess a greater number of eigenmodes than their lossless counterparts, and that these "loss guided" modes attenuate much more rapidly than conventional modes. Another contribution from this dissertation is the exploration of light trapping through the use of dielectric nanospheres embedded directly within the active layer of a thin silicon film. The primary benefit to this approach is that the device can utilize a surface nitride layer serving as an antireflective coating while still retaining the benefits of light trapping within the film. The end result is that light trapping and light injection are effectively decoupled from each other and may be independently optimized within a single photovoltaic device. The final contribution from this work is a direct numerical comparison between multiple light trapping schemes. This allows us to quantify the relative performances of various design techniques against one another and objectively determine which ideas tend to capture the most light. Using numerical simulation, this work directly compares the absorption

  18. Genomic similarity and kernel methods I: advancements by building on mathematical and statistical foundations.

    PubMed

    Schaid, Daniel J

    2010-01-01

    Measures of genomic similarity are the basis of many statistical analytic methods. We review the mathematical and statistical basis of similarity methods, particularly based on kernel methods. A kernel function converts information for a pair of subjects to a quantitative value representing either similarity (larger values meaning more similar) or distance (smaller values meaning more similar), with the requirement that it must create a positive semidefinite matrix when applied to all pairs of subjects. This review emphasizes the wide range of statistical methods and software that can be used when similarity is based on kernel methods, such as nonparametric regression, linear mixed models and generalized linear mixed models, hierarchical models, score statistics, and support vector machines. The mathematical rigor for these methods is summarized, as is the mathematical framework for making kernels. This review provides a framework to move from intuitive and heuristic approaches to define genomic similarities to more rigorous methods that can take advantage of powerful statistical modeling and existing software. A companion paper reviews novel approaches to creating kernels that might be useful for genomic analyses, providing insights with examples [1].

  19. Advanced numerical methods for three dimensional two-phase flow calculations

    SciTech Connect

    Toumi, I.; Caruge, D.

    1997-07-01

    This paper is devoted to new numerical methods developed for both one and three dimensional two-phase flow calculations. These methods are finite volume numerical methods and are based on the use of Approximate Riemann Solvers concepts to define convective fluxes versus mean cell quantities. The first part of the paper presents the numerical method for a one dimensional hyperbolic two-fluid model including differential terms as added mass and interface pressure. This numerical solution scheme makes use of the Riemann problem solution to define backward and forward differencing to approximate spatial derivatives. The construction of this approximate Riemann solver uses an extension of Roe`s method that has been successfully used to solve gas dynamic equations. As far as the two-fluid model is hyperbolic, this numerical method seems very efficient for the numerical solution of two-phase flow problems. The scheme was applied both to shock tube problems and to standard tests for two-fluid computer codes. The second part describes the numerical method in the three dimensional case. The authors discuss also some improvements performed to obtain a fully implicit solution method that provides fast running steady state calculations. Such a scheme is not implemented in a thermal-hydraulic computer code devoted to 3-D steady-state and transient computations. Some results obtained for Pressurised Water Reactors concerning upper plenum calculations and a steady state flow in the core with rod bow effect evaluation are presented. In practice these new numerical methods have proved to be stable on non staggered grids and capable of generating accurate non oscillating solutions for two-phase flow calculations.

  20. Dipolarization front and current disruption

    NASA Astrophysics Data System (ADS)

    Lui, A. T. Y.

    2016-10-01

    The modification of current density on the dawn-dusk cross section of the magnetotail with the earthward approach of a dipolarization front (DF) is examined through the recently published results of a three-dimensional (3-D) particle-in-cell (PIC) simulation. It is found that the current density intensifies by 37% abruptly within 1.5 ion gyrotime as the DF approaches and shows localized regions with north-south extrusions. After reaching its peak value, it undergoes a drastic current reduction (DCR) by 65% within 2 ion gyrotime. Breakdown of the frozen-in condition occurs in the neutral sheet region in association with DCR, demonstrating the non-MHD behavior of the phenomenon. The evolution of current density from this 3-D PIC simulation bears several similarities to those observed for the current disruption (CD) phenomenon, such as explosive growth and disruption of the current density leading to a breakdown of the frozen-in condition. The evolution is also similar to those from a previous two-dimensional (2-D) PIC simulation specially designed to investigate the nonlinear evolution of the cross-field current instability for CD. One interpretation of these findings is that CD and substorm triggering can be associated with earthward intrusion of a DF into the near-Earth plasma sheet as indicated by previous Cluster and Time History of Events and Macroscale Interactions during Substorms observations. An alternative interpretation is that both DF and CD are consequences of a global evolution from an ion-tearing-like instability of the magnetotail.