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Sample records for aero medical laboratory

  1. [Flight nurses' comprehension about their role in the multiprofesional team of aero-medical transport].

    PubMed

    Scuissiato, Dayane Reinhardt; Boffi, Letícia Valois; da Rocha, Roseline da Rocha; Montezeli, Juliana Helena; Bordin, Michelle Taverna; Peres, Aida Maris

    2012-01-01

    This is a descriptive qualitative research which aimed at identifying the flight nurses' comprehension by about their role in the aero-medical multiprofesional team. A semi-structured interview was carried out with eight flight nurses from Curitiba-PR, from June to August 2009. The speeches were analyzed by the content analysis, from which three categories emerged. The first describes the responsibilities of the flight nurses as managers of the aero-medical mission, planning for before, during and after the transport, what includes the aircraft check-list and knowledge of the patient's case. The second category deals with aspects of these professionals as care providers to the aero-transferred patient. The third describes communication and team-work as fundamental requirements for flight nurses. It was concluded that the nurse in aero-medical team mixes management and caring in his/her professional practice by the use of specific competences.

  2. FJ44 Turbofan Engine Test at NASA Glenn Research Center's Aero-Acoustic Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    Lauer, Joel T.; McAllister, Joseph; Loew, Raymond A.; Sutliff, Daniel L.; Harley, Thomas C.

    2009-01-01

    A Williams International FJ44-3A 3000-lb thrust class turbofan engine was tested in the NASA Glenn Research Center s Aero-Acoustic Propulsion Laboratory. This report presents the test set-up and documents the test conditions. Farfield directivity, in-duct unsteady pressures, duct mode data, and phased-array data were taken and are reported separately.

  3. Medical Laboratory Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document, which is designed for use in developing a tech prep competency profile for the occupation of medical laboratory technician, lists technical competencies and competency builders for 18 units pertinent to the health technologies cluster in general and 8 units specific to the occupation of medical laboratory technician. The following…

  4. The Confederate medical laboratories.

    PubMed

    Hasegawa, Guy R; Hambrecht, F Terry

    2003-12-01

    During the Civil War, the scarcity and expense of imported drugs forced the Confederate Army to establish several medical laboratories to manufacture drugs for military use. The laboratories produced medicines from indigenous plants and also made non-plant-based drugs. The Confederate Surgeon General and the Chief Purveyor in Richmond, VA, coordinated activities of most of the laboratories. The laboratories employed talented and resourceful personnel and manufactured a large volume and wide variety of drugs, the most useful of which included ether, chloroform, and opiates. The pharmaceutical quality of the laboratories' output was evidently uneven. Empirical testing in military hospitals helped determine the clinical value of indigenous remedies. The Confederate medical laboratories participated in a coordinated effort to supply the Army with substitutes for drugs whose availability was curtailed or uncertain.

  5. [Accreditation of medical laboratories].

    PubMed

    Horváth, Andrea Rita; Ring, Rózsa; Fehér, Miklós; Mikó, Tivadar

    2003-07-27

    In Hungary, the National Accreditation Body was established by government in 1995 as an independent, non-profit organization, and has exclusive rights to accredit, amongst others, medical laboratories. The National Accreditation Body has two Specialist Advisory Committees in the health care sector. One is the Health Care Specialist Advisory Committee that accredits certifying bodies, which deal with certification of hospitals. The other Specialist Advisory Committee for Medical Laboratories is directly involved in accrediting medical laboratory services of health care institutions. The Specialist Advisory Committee for Medical Laboratories is a multidisciplinary peer review group of experts from all disciplines of in vitro diagnostics, i.e. laboratory medicine, microbiology, histopathology and blood banking. At present, the only published International Standard applicable to laboratories is ISO/IEC 17025:1999. Work has been in progress on the official approval of the new ISO 15189 standard, specific to medical laboratories. Until the official approval of the International Standard ISO 15189, as accreditation standard, the Hungarian National Accreditation Body has decided to progress with accreditation by formulating explanatory notes to the ISO/IEC 17025:1999 document, using ISO/FDIS 15189:2000, the European EC4 criteria and CPA (UK) Ltd accreditation standards as guidelines. This harmonized guideline provides 'explanations' that facilitate the application of ISO/IEC 17025:1999 to medical laboratories, and can be used as a checklist for the verification of compliance during the onsite assessment of the laboratory. The harmonized guideline adapted the process model of ISO 9001:2000 to rearrange the main clauses of ISO/IEC 17025:1999. This rearrangement does not only make the guideline compliant with ISO 9001:2000 but also improves understanding for those working in medical laboratories, and facilitates the training and education of laboratory staff. With the

  6. Traversing Microphone Track Installed in NASA Lewis' Aero-Acoustic Propulsion Laboratory Dome

    NASA Technical Reports Server (NTRS)

    Bauman, Steven W.; Perusek, Gail P.

    1999-01-01

    The Aero-Acoustic Propulsion Laboratory is an acoustically treated, 65-ft-tall dome located at the NASA Lewis Research Center. Inside this laboratory is the Nozzle Acoustic Test Rig (NATR), which is used in support of Advanced Subsonics Technology (AST) and High Speed Research (HSR) to test engine exhaust nozzles for thrust and acoustic performance under simulated takeoff conditions. Acoustic measurements had been gathered by a far-field array of microphones located along the dome wall and 10-ft above the floor. Recently, it became desirable to collect acoustic data for engine certifications (as specified by the Federal Aviation Administration (FAA)) that would simulate the noise of an aircraft taking off as heard from an offset ground location. Since nozzles for the High-Speed Civil Transport have straight sides that cause their noise signature to vary radially, an additional plane of acoustic measurement was required. Desired was an arched array of 24 microphones, equally spaced from the nozzle and each other, in a 25 off-vertical plane. The various research requirements made this a challenging task. The microphones needed to be aimed at the nozzle accurately and held firmly in place during testing, but it was also essential that they be easily and routinely lowered to the floor for calibration and servicing. Once serviced, the microphones would have to be returned to their previous location near the ceiling. In addition, there could be no structure could between the microphones and the nozzle, and any structure near the microphones would have to be designed to minimize noise reflections. After many concepts were considered, a single arched truss structure was selected that would be permanently affixed to the dome ceiling and to one end of the dome floor.

  7. [ISO 15189 medical laboratory accreditation].

    PubMed

    Aoyagi, Tsutomu

    2004-10-01

    This International Standard, based upon ISO/IEC 17025 and ISO 9001, provides requirements for competence and quality that are particular to medical laboratories. While this International Standard is intended for use throughout the currently recognized disciplines of medical laboratory services, those working in other services and disciplines will also find it useful and appropriate. In addition, bodies engaged in the recognition of the competence of medical laboratories will be able to use this International Standard as the basis for their activities. The Japan Accreditation Board for Conformity Assessment (AB) and the Japanese Committee for Clinical Laboratory Standards (CCLS) are jointly developing the program of accreditation of medical laboratories. ISO 15189 requirements consist of two parts, one is management requirements and the other is technical requirements. The former includes the requirements of all parts of ISO 9001, moreover it includes the requirement of conformity assessment body, for example, impartiality and independence from any other party. The latter includes the requirements of laboratory competence (e.g. personnel, facility, instrument, and examination methods), moreover it requires that laboratories shall participate proficiency testing(s) and laboratories' examination results shall have traceability of measurements and implement uncertainty of measurement. Implementation of ISO 15189 will result in a significant improvement in medical laboratories management system and their technical competence. The accreditation of medical laboratory will improve medical laboratory service and be useful for patients.

  8. Medical Laboratory Assistant. Student's Manual.

    ERIC Educational Resources Information Center

    Barnett, Sara

    This student's manual for the medical laboratory student is one of a series of self-contained, individualized instructional materials for students enrolled in training within the allied health field. It is intended to provide study materials and learning activities that are general enough for all medical laboratory students to use to enhance their…

  9. Medical Laboratory Assistant. Laboratory Occupations Cluster.

    ERIC Educational Resources Information Center

    Michigan State Univ., East Lansing. Coll. of Agriculture and Natural Resources Education Inst.

    This task-based curriculum guide for medical laboratory assistant is intended to help the teacher develop a classroom management system where students learn by doing. Introductory materials include a Dictionary of Occupational Titles job code and title sheet, a career ladder, a matrix relating duty/task numbers to job titles, and a task list. Each…

  10. Integrated Line-of-Sight Modeling of the Airborne Aero-Optics Laboratory

    DTIC Science & Technology

    2013-09-01

    compensator. The PID coefficients were adjusted to match the measured behavior. The measured and tuned results are shown in Fig. 6. Measured Tuned ...strain energy in the bond between them. As with the measured data, this mode is destabilized in the tuned model as shown in Figure 6 with the PID ...uncertainty with model tuning based on available experimental measurements was examined for one flight condition. 2. INTRODUCTION The Airborne Aero

  11. Laboratory Procedures for Medical Assistants.

    ERIC Educational Resources Information Center

    Johnson, Pauline

    The purpose of the manual is to provide the medical assisting student a text which presents the common laboratory procedures in use today in physician's offices. The procedures for performing a complete urinalysis are outlined, along with those for carrying out various hematological tests. Information is also presented to help the student learn to…

  12. [Quality standards for medical laboratories].

    PubMed

    Pascal, P; Beyerle, F

    2006-07-01

    In France, medical laboratories must engage a quality approach according to the standard guide de bonne exécution des analyses (GBEA) and, for hospital laboratories, according to the Agence nationale d'évaluation en santé (Anaes). Except the GBEA and the Anaes handbook, which are obligatory standards by regulations, the biologists can choose, for a complementary and voluntary quality process, between the standards ISO 9001, ISO 17025 or ISO 15189. Our aim is to shed light on the advantages of these five standards by realizing a comparative study of their requirements. This work enabled us to highlight a great number of similarities and to raise the characteristics of these five standards. According to their objectives, the biologists will choose a recognition of their quality management system with an ISO 9001 certification or a recognition extended to the technical skills with an ISO 17025 or ISO 15189 accreditation. The contents of these last two documents are rather close and both integrate requirements of the standard ISO 9001. The standard ISO 17025 is, at first sight, rather distant from the biological analysis, requiring many efforts of adaptation, just like the ISO 9001 standard. The standard ISO 15189 seems to be well adapted but more constraining seeing the details requirements level needed. It necessitates a perfect control of the preanalytical phase, which is difficult to acquire in a clinical framework where the biological fluids are not taken by the laboratory staff.

  13. Emotional Intelligence in Medical Laboratory Science

    ERIC Educational Resources Information Center

    Price, Travis

    2013-01-01

    The purpose of this study was to explore the role of emotional intelligence (EI) in medical laboratory science, as perceived by laboratory administrators. To collect and evaluate these perceptions, a survey was developed and distributed to over 1,400 medical laboratory administrators throughout the U.S. during January and February of 2013. In…

  14. Medical and Clinical Laboratory Technologists and Technicians

    MedlinePlus

    ... examine and identify bacteria and other microorganisms. Molecular biology technologists perform complex protein and nucleic acid tests ... medical laboratory scientist degree, includes courses in chemistry, biology, microbiology, math, and statistics. Coursework emphasizes laboratory skills, ...

  15. Guide for Program Planning: Medical Laboratory Technician.

    ERIC Educational Resources Information Center

    Kahler, Carol, Ed.; And Others

    Prepared by the American Association of Junior Colleges and the National Council on Medical Technology Education, this guide discusses programs for career-entry supportive medical laboratory personnel which have been cooperatively planned by junior college personnel and the medical community, particularly pathologists and medical technologists.…

  16. Emotional intelligence in medical laboratory science

    NASA Astrophysics Data System (ADS)

    Price, Travis

    The purpose of this study was to explore the role of emotional intelligence (EI) in medical laboratory science, as perceived by laboratory administrators. To collect and evaluate these perceptions, a survey was developed and distributed to over 1,400 medical laboratory administrators throughout the U.S. during January and February of 2013. In addition to demographic-based questions, the survey contained a list of 16 items, three skills traditionally considered important for successful work in the medical laboratory as well as 13 EI-related items. Laboratory administrators were asked to rate each item for its importance for job performance, their satisfaction with the item's demonstration among currently working medical laboratory scientists (MLS) and the amount of responsibility college-based medical laboratory science programs should assume for the development of each skill or attribute. Participants were also asked about EI training in their laboratories and were given the opportunity to express any thoughts or opinions about EI as it related to medical laboratory science. This study revealed that each EI item, as well as each of the three other items, was considered to be very or extremely important for successful job performance. Administrators conveyed that they were satisfied overall, but indicated room for improvement in all areas, especially those related to EI. Those surveyed emphasized that medical laboratory science programs should continue to carry the bulk of the responsibility for the development of technical skills and theoretical knowledge and expressed support for increased attention to EI concepts at the individual, laboratory, and program levels.

  17. Medical Office Laboratory Procedures: Course Proposal. Revised.

    ERIC Educational Resources Information Center

    Baker, Eleanor

    A proposal is presented for a Community College of Philadelphia course, entitled "Medical Office Laboratory Procedures," which provides a laboratory introduction to microscopic and chemical analysis of blood and urine as performed in the physician's office. Following a standard cover form, a statement of the purpose of the course discusses course…

  18. Medical Laboratory Technician--Microbiology (AFSC 90470).

    ERIC Educational Resources Information Center

    Thompson, Joselyn H.

    This four-volume student text is designed for use by Air Force personnel enrolled in a self-study extension course for medical laboratory technicians. Covered in the individual volumes are laboratory procedures in clinical bacteriology (the history of bacteriology; aseptic techniques and sterilization procedures; bacterial morphology and…

  19. Aid for the Medical Laboratory

    NASA Technical Reports Server (NTRS)

    1986-01-01

    A process for separating chemical compounds in fluids resulted from a Jet Propulsion Laboratory (JPL)/LAPD project. The technique involves pouring a blood or urine sample into an extraction tube where packing material contained in a disposable tube called an "extraction column" absorbs water and spreads the specimen as a thin film, making it easy to identify specific components. When a solvent passes through the packing material, the desired compound dissolves and exits through the tube's bottom stem and is collected. Called AUDRI, Automated Drug Identification, it is commercially produced by Analytichem International which has successfully advanced the original technology.

  20. The medical laboratory scientist in the clinical chemistry service laboratory.

    PubMed

    Georges, R J

    1983-02-26

    The recent opening of an official register for medical laboratory scientists in South Africa has prompted an examination of the professional role, training and qualification of one particular group of scientists, namely clinical chemists working in hospital pathology departments. Lack of recognition of the potential contribution of these non-medical graduates towards improved health care, together with the lack of facilities for their professional advancement, has hitherto inhibited the growth and development of clinical chemistry in this country. An urgent need is the local establishment of a specialist postgraduate qualification open to the non-medical clinical chemist.

  1. The role of the medical laboratory director.

    PubMed

    Friedberg, Richard C; Rauch, Carol A

    2007-12-01

    The American Medical Association notes in its Principles of Medical Ethics that a physician "shall be dedicated to provide competent medical service with compassion and respect for human dignity." As physicians whose profession involves the medical direction of pathology and clinical laboratory services, pathologists strive to provide high-quality, cost-effective services to support the needs of patient care. These services must be provided under the aegis of extensive legal and regulatory mandates of various governmental and nongovernmental entities. To accomplish his/her task, the pathologist can use tools of evidence-based medicine and clinical practice guidelines together with his/her medical and scientific training and experience. At the same time, the Medical Director must be able to measure and demonstrate the value of his/her contribution in today's competitive environment.

  2. Health and safety in medical laboratories*

    PubMed Central

    Harrington, J. M.

    1982-01-01

    There has been a large increase in the number of persons employed in medical laboratories in the last 25 years. These workers are exposed to a variety of infective agents in the course of their work, the most important being Mycobacterium tuberculosis, Salmonella typhi, Brucella spp., and serum hepatitis virus. Chemical and physical hazards include toxic chemicals, lacerations, skin disease, and possibly cancer. Current knowledge of safe working practice in laboratories leaves much to be desired and there is an urgent need for both internationally agreed codes of safe practice and the development of guidelines for the medical surveillance of laboratory workers. The World Health Organization is developing such guidelines in an attempt to protect the health of workers employed in the investigation of ill health in others. PMID:6979421

  3. Increasing the visibility, voice, and clout of medical laboratory scientists.

    PubMed

    Stuart, J Michele

    2005-09-27

    Medical laboratory science professionals are represented by several national certifying agencies, yet few promote a common professional identity. People outside the profession seldom recognize that medical laboratory scientists (MLSs) perform a myriad of complex laboratory tests. Among medical laboratory scientists, there exists a perceived lack of power, prestige, and autonomy. By identifying and supporting common issues and promoting the profession, medical laboratory scientists can gain professional visibility, voice, clout, and unification.

  4. Inflammation Thread Runs across Medical Laboratory Specialities

    PubMed Central

    Lung, Thomas; Risch, Lorenz; Risch, Martin; Medina Escobar, Pedro; Bodmer, Thomas

    2016-01-01

    We work on the assumption that four major specialities or sectors of medical laboratory assays, comprising clinical chemistry, haematology, immunology, and microbiology, embraced by genome sequencing techniques, are routinely in use. Medical laboratory markers for inflammation serve as model: they are allotted to most fields of medical lab assays including genomics. Incessant coding of assays aligns each of them in the long lists of big data. As exemplified with the complement gene family, containing C2, C3, C8A, C8B, CFH, CFI, and ITGB2, heritability patterns/risk factors associated with diseases with genetic glitch of complement components are unfolding. The C4 component serum levels depend on sufficient vitamin D whilst low vitamin D is inversely related to IgG1, IgA, and C3 linking vitamin sufficiency to innate immunity. Whole genome sequencing of microbial organisms may distinguish virulent from nonvirulent and antibiotic resistant from nonresistant varieties of the same species and thus can be listed in personal big data banks including microbiological pathology; the big data warehouse continues to grow. PMID:27493451

  5. Perceptions of Competence of Three Levels of Medical Laboratory Personnel.

    ERIC Educational Resources Information Center

    Davis, Judith A.

    Commonalities and differences in the perception of competence among three levels of medical laboratory personnel were assessed through a survey of 100 educators, chief technologists, and working technicians. Respondents rated medical technologists (MTs), medical laboratory technicians (MLTs), and certified laboratory assistants (CLAs) on 270 tasks…

  6. Medical Laboratory Technician (Chemistry and Urinalysis). (AFSC 92470).

    ERIC Educational Resources Information Center

    Thompson, Joselyn H.

    This four-volume student text is designed for use by Air Force personnel enrolled in a self-study extension course for medical laboratory technicians. Covered in the individual volumes are medical laboratory administration and clinical chemistry (career opportunities, general laboratory safety and materials, general medical laboratory…

  7. AeroValve Experimental Test Data Final Report

    SciTech Connect

    Noakes, Mark W.

    2014-09-01

    This report documents the collection of experimental test data and presents performance characteristics for the AeroValve brand prototype pneumatic bidirectional solenoid valves tested at the Oak Ridge National Laboratory (ORNL) in July/August 2014 as part of a validation of AeroValve energy efficiency claims. The test stand and control programs were provided by AeroValve. All raw data and processing are included in the report attachments.

  8. Polish Code of Ethics of a Medical Laboratory Specialist

    PubMed Central

    2014-01-01

    Along with the development of medicine, increasingly significant role has been played by the laboratory diagnostics. For over ten years the profession of the medical laboratory specialist has been regarded in Poland as the autonomous medical profession and has enjoyed a status of one of public trust. The process of education of medical laboratory specialists consists of a five-year degree in laboratory medicine, offered at Medical Universities, and of a five-year Vocational Specialization in one of the fields of laboratory medicine such as clinical biochemistry, medical microbiology, medical laboratory toxicology, medical laboratory cytomorphology and medical laboratory transfusiology. An important component of medical laboratory specialists’ identity is awareness of inherited ethos obtained from bygone generations of workers in this particular profession and the need to continue its further development. An expression of this awareness is among others Polish Code of Ethics of a Medical Laboratory Specialist (CEMLS) containing a set of values and a moral standpoint characteristic of this type of professional environment. Presenting the ethos of the medical laboratory specialist is a purpose of this article. Authors focus on the role CEMLS plays in areas of professional ethics and law. Next, they reconstruct the Polish model of ethos of medical diagnostic laboratory personnel. An overall picture consists of a presentation of the general moral principles concerning execution of this profession and rules of conduct in relations with the patient, own professional environment and the rest of the society. Polish model of ethical conduct, which is rooted in Hippocratic medical tradition, harmonizes with the ethos of medical laboratory specialists of other European countries and the world. PMID:27683468

  9. ISO and CEN documents on quality in medical laboratories.

    PubMed

    Kenny, D

    2001-07-20

    The forthcoming international standard ISO 15189 "Quality management in the medical laboratory" is a document of great importance for the development of quality systems and accreditation for medical/clinical laboratories. For the first time, there will be an internationally recognized standard designed specifically for the accreditation of medical laboratories. The document takes into account the special requirements imposed by the medical environment and by the essential contribution of the medical laboratory service to patient care. It recognizes that medical laboratories must provide not only testing of patient samples, but also advisory, interpretative and educational services. A further document, still in draft form (ISO/DIS 15190), deals with safety management for medical laboratories. ISO 15189 (and probably 15190 also) are expected be adopted by CEN as a European Standard (EN).

  10. Sandia National Laboratories Medical Isotope Reactor concept.

    SciTech Connect

    Coats, Richard Lee; Dahl, James J.; Parma, Edward J., Jr.

    2010-04-01

    This report describes the Sandia National Laboratories Medical Isotope Reactor and hot cell facility concepts. The reactor proposed is designed to be capable of producing 100% of the U.S. demand for the medical isotope {sup 99}Mo. The concept is novel in that the fuel for the reactor and the targets for the {sup 99}Mo production are the same. There is no driver core required. The fuel pins that are in the reactor core are processed on a 7 to 21 day irradiation cycle. The fuel is low enriched uranium oxide enriched to less than 20% {sup 235}U. The fuel pins are approximately 1 cm in diameter and 30 to 40 cm in height, clad with Zircaloy (zirconium alloy). Approximately 90 to 150 fuel pins are arranged in the core in a water pool {approx}30 ft deep. The reactor power level is 1 to 2 MW. The reactor concept is a simple design that is passively safe and maintains negative reactivity coefficients. The total radionuclide inventory in the reactor core is minimized since the fuel/target pins are removed and processed after 7 to 21 days. The fuel fabrication, reactor design and operation, and {sup 99}Mo production processing use well-developed technologies that minimize the technological and licensing risks. There are no impediments that prevent this type of reactor, along with its collocated hot cell facility, from being designed, fabricated, and licensed today.

  11. Guide for Training Medical Laboratory Technicians. Fourth Edition.

    ERIC Educational Resources Information Center

    American Medical Technologists, Park Ridge, IL.

    This document is intended to assist educators in the development of medical laboratory technician training programs. The following elements are included in the document: (1) an introduction; (2) the American Medical Technologists' Code of Ethics; (3) suggested curricula for medical laboratory technician programs for a 12-month course and an…

  12. Accountability through regulation in Ontario's Medical Laboratory Sector.

    PubMed

    Gamble, Brenda; Bourne, Lavern; Deber, Raisa B

    2014-09-01

    Although the use of performance indicators for the analytical (and highly measurable) phase of the medical laboratory process has had a long and successful history, it is now recognized that the value of a laboratory test is embedded in a system of care. This case study, using both documents and interview data, examines the approaches to accountability in the Ontario Medical Laboratory Sector, noting both the challenges and benefits. This sector relies heavily on the regulation instrument, including a requirement that all medical laboratories licensed by the provincial government must follow the guidelines set out by the Quality Management Program - Laboratory Services. We found the greatest challenges exist in the pre-analytical phase (where a large portion of total laboratory errors occur), particularly the interface between the laboratory and other providers.

  13. Accountability through Regulation in Ontario's Medical Laboratory Sector

    PubMed Central

    Gamble, Brenda; Bourne, Lavern; Deber, Raisa B.

    2014-01-01

    Although the use of performance indicators for the analytical (and highly measurable) phase of the medical laboratory process has had a long and successful history, it is now recognized that the value of a laboratory test is embedded in a system of care. This case study, using both documents and interview data, examines the approaches to accountability in the Ontario Medical Laboratory Sector, noting both the challenges and benefits. This sector relies heavily on the regulation instrument, including a requirement that all medical laboratories licensed by the provincial government must follow the guidelines set out by the Quality Management Program – Laboratory Services. We found the greatest challenges exist in the pre-analytical phase (where a large portion of total laboratory errors occur), particularly the interface between the laboratory and other providers. PMID:25305390

  14. [Quality management system in the medical laboratory--ISO15189 and laboratory accreditation].

    PubMed

    Kubono, Katsuo

    2004-03-01

    Medical laboratory services are essential to patient care and therefore should meet the needs of all patients and clinical personnel responsible for human health care. Recently, ISO15189, the first quality management ISO system for medical laboratories, has attracted the attention of all medical laboratories. ISO 15189:2003, Medical laboratories--Particular requirements for quality and competence, provides a framework for the design and improvement of process-based quality management systems by medical laboratories. It is based on ISO17025:1999, General requirements for the competence of testing and calibration laboratories, but provides specific requirements for implementation in medical laboratories. This will help medical laboratories to comply with regulatory requirements, to meet the expectations of their clients and, most importantly, to improve and maintain their service to patients. ISO15189 will be an important template for assessing and recognizing the competence of medical laboratories in their technical capacity and the effective quality management of a professional service and its staff--with or without the aim of accreditation.

  15. Medical Service Clinical Laboratory Procedure--Hematology.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    Presented are laboratory studies focusing on blood cells and the complete scheme of blood coagulation. Formed is the basis for the following types of laboratory operations: (1) distinguishing the morphology of normal and abnormal blood cells; (2) measuring the concentrations or number of blood cells; (3) measuring concentration and detecting…

  16. Career research opportunities for the medical laboratory scientist.

    PubMed

    McGlasson, David L

    2011-01-01

    Medical Laboratory Scientists (MLS) typically practice in hospital laboratories; however there are multiple alternatives in research. This article details the advantages of working in a variety of research laboratory settings. These include public institutions, federal laboratory workplaces, private facilities, and industry settings. A view of the different research laboratory settings such as public institutions, federal laboratory workplaces, private facilities, and industry settings will be provided. An assessment on how MLS professionals can prepare for a career in research is outlined and the report concludes with a brief summary of the various aspects of the research setting.

  17. Computer laboratory in medical education for medical students.

    PubMed

    Hercigonja-Szekeres, Mira; Marinović, Darko; Kern, Josipa

    2009-01-01

    Five generations of second year students at the Zagreb University School of Medicine were interviewed through an anonymous questionnaire on their use of personal computers, Internet, computer laboratories and computer-assisted education in general. Results show an advance in students' usage of information and communication technology during the period from 1998/99 to 2002/03. However, their positive opinion about computer laboratory depends on installed capacities: the better the computer laboratory technology, the better the students' acceptance and use of it.

  18. IVD industry role for quality and accreditation in medical laboratories.

    PubMed

    Bremond, J; Plebani, M

    2001-07-20

    Manufacturers of in vitro diagnostic (IVD) medical devices and laboratory management have become integral partners in building and improving the quality of laboratory services. There is an increasing awareness that quality is inherent in the design of any reagent or analytical system. In vitro diagnostic medical devices should provide patients, users and third parties with a high level of health protection. Therefore, both manufacturers and users must work in partnership for continual improvement. For manufacturers, standards such as ISO 9000 already exist to guide applications of quality practices. In the field of laboratory medicine, the availability of a specific, universal standard (ISO/DIS 15189) for quality management in medical laboratories will represent a great opportunity for harmonising medical laboratories at an international level. In addition, accreditation of medical laboratories according to the proposed ISO 15189 standard can help develop the relationships between laboratories, and the biological follow-up of travelling patients. Manufacturers are able to help laboratory management to reach a high level of quality, not only by providing high value products, but also on the basis of their own experience of ISO 9000 certification.

  19. Medical laboratory accreditation: a Hong Kong perspective.

    PubMed

    Chang, Alexander R

    2002-04-01

    This is an account of the accreditation of the Surgical Pathology, Cytopathology, Autopsy Service, Haematology, Blood Bank, Bone Marrow Transplant and Electronmicroscopy Laboratories of the Department of Anatomical and Cellular Pathology, the Prince of Wales Hospital, Shatin, New Territories, Hong Kong, SAR, China, the first of their category to be accredited in the Special Administrative Region. The Australian-based National Association of Testing Authorities (NATA) used standards formulated by the National Pathology Accreditation Advisory Council (NPAAC) to measure the performance of the laboratory sections and to determine whether the laboratory service was of a sufficient standard to be granted accreditation. Some practices dating back to the colonial period required attention, while eliciting the support of staff at all levels was essential for achieving accreditation. Some cultural factors had to be taken into account when implementing changes. Finally, successful accreditation has provided the impetus for other Hong Kong laboratories to become accredited and this will have a beneficial flow-on effect for the entire region.

  20. Medical Service Clinical Laboratory Procedures--Bacteriology.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    This manual presents laboratory procedures for the differentiation and identification of disease agents from clinical materials. Included are procedures for the collection of specimens, preparation of culture media, pure culture methods, cultivation of the microorganisms in natural and simulated natural environments, and procedures in…

  1. MEDICAL LABORATORY ASSISTANT, A SUGGESTED GUIDE FOR A TRAINING PROGRAM.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC.

    INFORMATION IS GIVEN TO ASSIST IN ORGANIZING AND ADMINISTERING A TRAINING PROGRAM FOR MEDICAL LABORATORY ASSISTANTS IN A VARIETY OF SETTINGS AND TO PROVIDE GUIDANCE IN ESTABLISHING NEW PROGRAMS AND IN EVALUATING EXISTING ONES. THE MATERIAL WAS PREPARED UNDER THE DIRECTION OF THE NATIONAL COMMITTEE FOR CAREERS IN MEDICAL TECHNOLOGY. PATHOLOGISTS…

  2. Careers for the Handicapped in Medical Laboratories. Final Report.

    ERIC Educational Resources Information Center

    Kenworthy, Betts

    A survey of all hospitals accredited by the American Hospital Association was made to ascertain how the physically handicapped performed at jobs in medical laboratories. Detailed questionnaires were sent to laboratory directors, and the results were processed by computer to determine whether correlations exist between the number of disabled…

  3. Aero dopes and varnishes

    NASA Technical Reports Server (NTRS)

    Britton, H T S

    1927-01-01

    Before proceeding to discuss the preparation of dope solutions, it will be necessary to consider some of the essential properties which should be possessed of a dope film, deposited in and on the surface of an aero fabric. The first is that it should tighten the material and second it should withstand weathering.

  4. American Medical Technologists' (AMT) Position on Licensure for Medical Laboratory Personnel.

    ERIC Educational Resources Information Center

    American Medical Technologists, Park Ridge, IL.

    The American Medical Technologists organization opposes licensure for medical laboratory personnel unless there is consensus among all the groups representing generalist laboratory practitioners as to qualifications, titles, accreditation, and certification policies. Licensure is a restrictive and protectionistic measure, and American Medical…

  5. Medical Services: Veterinary/Medical Food Inspection and Laboratory Service

    DTIC Science & Technology

    2007-11-02

    or civilian equivalents will conduct sanitary inspections of commercial ice manufacturing estab- lishments and bottled water establishments in...establishments other than those of prime contractors Normally, veterinary/medical personnel inspect only the establish- ments that manufacture , process, store...through the manufacturing process. ( 2 ) T h e p r i m e c o n t r a c t o r d o e s n o t h a v e c o n t r o l p r o c e d u r e s 5AR 40–657/NAVSUPINST

  6. [Why medical consultation is needed in the clinical laboratory].

    PubMed

    Kawai, T

    1998-10-01

    During the 20th century, at least until the 1980s, clinical laboratory practice had been rapidly expanded, mainly because of a significant advancement in medicine as a whole and also in laboratory technology. However, recent economic changes in health care environment worldwide have been influencing greatly future trends in clinical laboratory practice. Four major macroeconomic forces drive change in clinical laboratory practice as follows; (1) Increasing cost of health care, (2) Implications of an aging population, (3) Social change in the patient population, and (4) Explosion of new technologies. Obviously, the increasing cost of health care is the primary driver. Considering a rapid change in the health care environment, clearly there are two separate pathways to be considered with regard to future modes of delivering patient care services through the clinical laboratory: commercial independent laboratories and hospital laboratories. In most hospital laboratories, in addition to high-quality, accurate and precise laboratory data being delivered through automated informatics in a timely fashion, laboratory physicians and other laboratorians should be available 24 hours a day and 7 days a week. The primary purpose of this approach is to develop a system in which the physician can order the most efficient number of tests, which will provide the maximum amount of clinically relevant informations most rapidly and most accurately at the least cost to the patient. Laboratory physicians must play a key role particularly in hospital laboratories. Their most important roles include those of a professional supplier of laboratory results being useful for health care and clinically relevant, and that of a consultative role for primary care physicians and other co-medical staffs to make important medical decision, based on laboratory results obtained. Therefore, the Japan Society of Clinical Pathology started in 1990 in publishing a series of proposed guidelines for adequate

  7. A professional development model for medical laboratory scientists working in the Core Laboratory.

    PubMed

    Ali, Faheem A; Pulido, Lila A; Garza, Melinda N; Amerson, Megan H; Greenhill, Brandy; Brown, Krystyna N; Lim, Shari K; Manyam, Venkatesara R; Nguyen, Hannah N; Prudhomme, Carrie C; Regan, Laura E; Sims, Willie R; Umeh, Afamefuna U; Williams, Rosemary; Tillman, Patricia K; Hu, Peter C

    2012-01-01

    The Division of Pathology and Laboratory Medicine at The University of Texas MD Anderson Cancer Center has implemented a professional development model designed to further the education, expertise, and experiences of medical laboratory scientists in the core laboratory. The professional development model (PDM) has four competency levels: Discovery, Application, Maturation and Expert. All levels require the medical laboratory scientist to learn new skill sets, complete task and projects, and meet continuing education and certification requirements. Each level encourages personal development, recognizes increased competencies, and sets high standards for all services provided. Upon completion of a level within a given timeframe, the medical laboratory scientist receives a salary adjustment based on the competency level completed.

  8. Aero/structural tailoring of engine blades (AERO/STAEBL)

    NASA Technical Reports Server (NTRS)

    Brown, K. W.

    1988-01-01

    This report describes the Aero/Structural Tailoring of Engine Blades (AERO/STAEBL) program, which is a computer code used to perform engine fan and compressor blade aero/structural numerical optimizations. These optimizations seek a blade design of minimum operating cost that satisfies realistic blade design constraints. This report documents the overall program (i.e., input, optimization procedures, approximate analyses) and also provides a detailed description of the validation test cases.

  9. European medical laboratory accreditation. Present situation and steps to harmonisation.

    PubMed

    Huisman, Wim

    2012-07-01

    Accreditation of medical laboratories in Europe is primarily according to ISO15189. The percentage of accredited laboratories is still small. The time spent on an assessment is quite different between countries. More important is the way the assessment process is carried out. Harmonisation in accrediting medical laboratories is the main task of the Health Care Committee within EA (European cooperation of Accreditation). The EFCC Working Group on Accreditation strongly contributes as the representative of laboratory professionals. An important item is the use of flexible scope. The intention is that all tests within a medical discipline are offered for accreditation. This is not yet normal practice. Other items concern accreditation of point-of-care testing (POCT) - reliability of the pre-analytical phase, when the phlebotomy is not done by the laboratory, and practical use of uncertainty and verification. Also the diversity in time spent for an assessment is discussed. The added value of accreditation is strongly dependent upon the assessors who have an important task. Their training and calibration needs continuous input. The medical laboratory professionals should participate in all aspects concerning the quality system, starting with the standard, working on the guidelines, the assessment itself, and input in the accreditation bodies.

  10. A Study of Mathematics Needed for Dental Laboratory Technology, Medical Laboratory Technology, and Respiratory Therapy.

    ERIC Educational Resources Information Center

    Roberts, Keith J.

    A study was conducted to determine what mathematics skills were needed for Dental Laboratory Technology, Medical Laboratory Technology, and Respiratory Therapy. Data obtained from studies, course outlines, textbooks, and reports were used to construct a 79-item mathematics skill questionnaire. This questionnaire was administered to employers,…

  11. [What does accreditation of medical microbiological laboratories mean to patients?].

    PubMed

    Asprang, Aud Frøysa; Jenum, Pål A

    2003-11-06

    Accreditation of a medical microbiological laboratory according to the ISO 17025 standard confirms that the analyses included in the accreditation are performed with high quality. This paper gives an overview over various quality aspects of direct importance to the patient and the patient's doctor: i) the relationship between the doctor and the laboratory; ii) the selection of relevant analyses; iii) the accuracy of the results; iv) sources and estimation of uncertainty; v) stability of test results; vi) review of complaints; and vii) interpretation of test results. Special aspects of medical microbiology in relation to accreditation are mentioned.

  12. MI-Lab - A Laboratory Environment for Medical Informatics Students.

    PubMed

    Brandt, Karsten; Löbe, Matthias; Schaaf, Michael; Jahn, Franziska; Winter, Alfred; Stäubert, Sebastian

    2016-01-01

    Medical research and health care highly depend on the use of information technology. There is a wide range of application systems (patient administration system, laboratory information system, communication server etc.) and heterogeneous data types (administrative data, clinical data, laboratory data, image data, genomic data etc.). Students and researchers do not often have the possibility to use productive application systems of e.g. hospitals or medical practices to gain practical experiences or examine new components and technologies. Therefore, the aim of this project is to develop a dedicated laboratory environment for patient health care and clinical research. Essential application systems were identified and a suitable architecture was designed for this purpose. It is accompanied by a teaching plan that considers learning modules for bachelor and master degrees in medical informatics. We implemented the laboratory environment called MI-Lab with multiple free and open source software components. All components are installed on virtual machines and/or Docker containers. This modular architecture creates a flexible system which can be deployed in various scenarios. The preliminary evaluation results suggests that laboratory environments like MI-Lab work well in teaching practical aspects of medical informatics and are widely accepted by students.

  13. A professional development model for medical laboratory scientists working in the immunohematology laboratory.

    PubMed

    Garza, Melinda N; Pulido, Lila A; Amerson, Megan; Ali, Faheem A; Greenhill, Brandy A; Griffin, Gary; Alvarez, Enrique; Whatley, Marsha; Hu, Peter C

    2012-01-01

    Transfusion medicine, a section of the Department of Laboratory Medicine at The University of Texas MD Anderson Cancer Center is committed to the education and advancement of its health care professionals. It is our belief that giving medical laboratory professionals a path for advancement leads to excellence and increases overall professionalism in the Immunohematology Laboratory. As a result of this strong commitment to excellence and professionalism, the Immunohematology laboratory has instituted a Professional Development Model (PDM) that aims to create Medical Laboratory Scientists (MLS) that are not only more knowledgeable, but are continually striving for excellence. In addition, these MLS are poised for advancement in their careers. The professional development model consists of four levels: Discovery, Application, Maturation, and Expert. The model was formulated to serve as a detailed path to the mastery of all process and methods in the Immunohematology Laboratory. Each level in the professional development model consists of tasks that optimize the laboratory workflow and allow for concurrent training. Completion of a level in the PDM is rewarded with financial incentive and further advancement in the field. The PDM for Medical Laboratory Scientists in the Immunohematology Laboratory fosters personal development, rewards growth and competency, and sets high standards for all services and skills provided. This model is a vital component of the Immunohematology Laboratory and aims to ensure the highest quality of care and standards in their testing. It is because of the success of this model and the robustness of its content that we hope other medical laboratories aim to reach the same level of excellence and professionalism, and adapt this model into their own environment.

  14. Naval Aerospace Medical Research Laboratory Bibliography, 1981-1986.

    DTIC Science & Technology

    1987-06-01

    n Ltd.. 6 pp., 1981. Olsen, R.G., Microwave-induced Developmental Defects in the Common Mealworm Tenerio mlit-ýr_--A Decade o’ Re-seaFch-, NAMRL-1283...Tri-service Aeromedical Research Panel Fall Technical Meeting , NAMRL Monograph 33, Naval Aerospace A Medical Research Laboratory, Pensacola, FL

  15. A History of Computer-Assisted Medical Diagnosis at Naval Submarine Medical Research Laboratory

    DTIC Science & Technology

    1993-05-01

    user documenta- tion 7 . The conversion was essentially ’line- Dental Pain Program for-line" to keep the knowledge representation (the "brains" of the...the 19. Caras, B. G., Fisherkeller, K. D., and management of acute dental pain - User’s Southerland D. G. (1989). MEDIC - Manual (NSMRL Report 1143...for "classic" presentations of dental pain marine Medical Research Laboratory. (NSMRL Report 1136). Groton, CT: Naval Submarine Medical Research 37

  16. Aero-optics analysis

    NASA Astrophysics Data System (ADS)

    Russell, Lynn D.

    1991-01-01

    The U.S. Army Strategic Defense Command (USASDC) has several ongoing and planned programs that utilize optical sensors aboard missiles traveling at hypersonic velocities in the atmosphere. Central to the missile homing problem are aero-optical effects upon a missile-borne sensor/seeker which looks through both an electromagnetic window and the flow field about the vehicle. Aspects of the problem include modeling and simulation of the flow field on incident radiation from a target, and finally, predicting the resultant image imperfections and error in apparent object position as perceived by the sensor.

  17. Mississippi Curriculum Framework for Medical Laboratory Technology Programs (CIP: 51.1004--Medical Laboratory Technology). Postsecondary Programs.

    ERIC Educational Resources Information Center

    Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

    This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the medical laboratory technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and…

  18. Medical and laboratory indicators of elder abuse and neglect.

    PubMed

    LoFaso, Veronica M; Rosen, Tony

    2014-11-01

    Elder abuse and neglect are highly prevalent but woefully underdetected and underreported. The presentation is rarely clear and requires the piecing together of clues that create a mosaic of the full picture. More research needed to better characterize findings that, when identified, can contribute to certainty in cases of suspected abuse. Medical and laboratory data can be helpful in the successful determination of abuse and neglect.

  19. Biorisk Assessment of Medical Diagnostic Laboratories in Nigeria

    PubMed Central

    Oladeinde, Bankole Henry; Omoregie, Richard; Odia, Ikponmwonsa; Osakue, Eguagie Osareniro; Imade, Odaro Stanley

    2013-01-01

    Background The aim of this study was to assess public and private medical diagnostic laboratories in Nigeria for the presence of biosafety equipment, devices, and measures. Methods A total of 80 diagnostic laboratories in biosafety level 3 were assessed for the presence of biosafety equipment, devices, and compliance rate with biosafety practices. A detailed questionnaire and checklist was used to obtain the relevant information from enlisted laboratories. Results The results showed the presence of an isolated unit for microbiological work, leak-proof working benches, self-closing doors, emergency exits, fire extinguisher(s), autoclaves, and hand washing sinks in 21.3%, 71.3%, 15.0%, 1.3%, 11.3%, 82.5%, and 67.5%, respectively, of all laboratories surveyed. It was observed that public diagnostic laboratories were significantly more likely to have an isolated unit for microbiological work (p = 0.001), hand washing sink (p = 0.003), and an autoclave (p ≤ 0.001) than private ones. Routine use of hand gloves, biosafety cabinet, and a first aid box was observed in 35.0%, 20.0%, and 2.5%, respectively, of all laboratories examined. Written standard operating procedures, biosafety manuals, and biohazard signs on door entrances were observed in 6.3%, 1.3%, and 3.8%, respectively, of all audited laboratories. No biosafety officer(s) or records of previous spills, or injuries and accidents, were observed in all diagnostic laboratories studied. Conclusion In all laboratories (public and private) surveyed, marked deficiencies were observed in the area of administrative control responsible for implementing biosafety. Increased emphasis on provision of biosafety devices and compliance with standard codes of practices issued by relevant authorities is strongly advocated. PMID:23961333

  20. AeroSpace Days 2013

    NASA Video Gallery

    At the eighth annual AeroSpace Days, first mom in space, Astronaut AnnaFisher, and Sen. Louise Lucas, interacted with students from Mack BennJr. Elementary School in Suffolk, Va. through NASA’s...

  1. An Analysis of Medical Laboratory Technology Journals' Instructions for Authors.

    PubMed

    Horvat, Martina; Mlinaric, Ana; Omazic, Jelena; Supak-Smolcic, Vesna

    2016-08-01

    Instructions for authors (IFA) need to be informative and regularly updated. We hypothesized that journals with a higher impact factor (IF) have more comprehensive IFA. The aim of the study was to examine whether IFA of journals indexed in the Journal Citation Reports 2013, "Medical Laboratory Technology" category, are written in accordance with the latest recommendations and whether the quality of instructions correlates with the journals' IF. 6 out of 31 journals indexed in "Medical Laboratory Technology" category were excluded (unsuitable or unavailable instructions). The remaining 25 journals were scored based on a set of 41 yes/no questions (score 1/0) and divided into four groups (editorial policy, research ethics, research integrity, manuscript preparation) by three authors independently (max score = 41). We tested the correlation between IF and total score and the difference between scores in separate question groups. The median total score was 26 (21-30) [portion of positive answers 0.63 (0.51-0.73)]. There was no statistically significant correlation between a journal's IF and the total score (rho = 0.291, P = 0.159). IFA included recommendations concerning research ethics and manuscript preparation more extensively than recommendations concerning editorial policy and research integrity (Ht = 15.91, P = 0.003). Some policies were poorly described (portion of positive answers), for example: procedure for author's appeal (0.04), editorial submissions (0.08), appointed body for research integrity issues (0.08). The IF of the "Medical Laboratory Technology" journals does not reflect a journals' compliance to uniform standards. There is a need for improving editorial policies and the policies on research integrity.

  2. [New aero-allergens].

    PubMed

    De Blay, F; Bessot, J C; Pauli, G

    1996-01-01

    As the number of proteins recognized as causing allergic respiratory diseases increases, new aero allergens have appeared in the animal and vegetable realms, both in home and professional environments. Lepidoglyphus destructor and Blomia tropicalis, two mites found in storage areas, are particularly important in agricultural areas and in homes. Over the last ten years, the frequency of reactions to cockroaches has also increased in several countries. The allergenicity of non-biting insects is a frequent cause of allergy in certain countries including Japan. Chironomides cause respiratory diseases in professional and outdoor environments. The important role of Alternaria, a mold, in producing severe asthma has also been demonstrated. The pathophysiology of pollen-induced asthma has been shown to result from pollen allergens carried by particles less than 5 microns in diameter. Cyprus and ash tree pollen also cause an increasing number of pollinoses and flowers can cause rhinitis and asthma. Respiratory allergy to Ficus benjamina inaugurated a new type of allergies caused airborne allergens from non-pollinating plants. Allergy to latex raises a particular problem for health care workers. The immunochemical structures of the major and minor airborne allergens are now better known and the homologous structures of different allergens largely explains certain cross-reactions. In the future, recombinant allergens will probably be used to better understand the role of allergens in inducing and maintaining the allergic reaction and should help in our approach to diagnosis and therapy.

  3. Hypersonic Interplanetary Flight: Aero Gravity Assist

    NASA Technical Reports Server (NTRS)

    Bowers, Al; Banks, Dan; Randolph, Jim

    2006-01-01

    The use of aero-gravity assist during hypersonic interplanetary flights is highlighted. Specifically, the use of large versus small planet for gravity asssist maneuvers, aero-gravity assist trajectories, launch opportunities and planetary waverider performance are addressed.

  4. Feasibility study of medical isotope production at Sandia National Laboratories

    SciTech Connect

    Massey, C.D.; Miller, D.L.; Carson, S.D.

    1995-12-01

    In late 1994, Sandia National Laboratories in Albuquerque, New Mexico, (SNL/NM), was instructed by the Department of Energy (DOE) Isotope Production and Distribution Program (IPDP) to examine the feasibility of producing medically useful radioisotopes using the Annular Core Research Reactor (ACRR) and the Hot Cell Facility (HCF). Los Alamos National Laboratory (LANL) would be expected to supply the targets to be irradiated in the ACRR. The intent of DOE would be to provide a capability to satisfy the North American health care system demand for {sup 99}Mo, the parent of {sup 99m}Tc, in the event of an interruption in the current Canadian supply. {sup 99m}Tc is used in 70 to 80% of all nuclear medicine procedures in the US. The goal of the SNL/NM study effort is to determine the physical plant capability, infrastructure, and staffing necessary to meet the North American need for {sup 99}Mo and to identify and examine all issues with potential for environmental impact.

  5. Generation and composition of medical wastes from private medical microbiology laboratories.

    PubMed

    Komilis, Dimitrios; Makroleivaditis, Nikolaos; Nikolakopoulou, Eftychia

    2017-03-01

    A study on the generation rate and the composition of solid medical wastes (MW) produced by private medical microbiology laboratories (PMML) was conducted in Greece. The novelty of the work is that no such information exists in the literature for this type of laboratories worldwide. Seven laboratories were selected with capacities that ranged from 8 to 88 examinees per day. The study lasted 6months and daily recording of MW weights was done over 30days during that period. The rates were correlated to the number of examinees, examinations and personnel. Results indicated that on average 35% of the total MW was hazardous (infectious) medical wastes (IFMW). The IFMW generation rates ranged from 11.5 to 32.5g examinee(-1) d(-1) while an average value from all 7 labs was 19.6±9.6g examinee(-1) d(-1) or 2.27±1.11g examination(-1) d(-1). The average urban type medical waste generation rate was 44.2±32.5g examinee(-1) d(-1). Using basic regression modeling, it was shown that the number of examinees and examinations can be predictors of the IFMW generation, but not of the urban type MW generation. The number of examinations was a better predictor of the MW amounts than the number of examinees. Statistical comparison of the means of the 7PMML was done with standard ANOVA techniques after checking the normality of the data and after doing the appropriate transformations. Based on the results of this work, it is approximated that 580 tonnes of infectious MW are generated annually by the PMML in Greece.

  6. The Lincoln Laboratory-Aerospace Medical Research Laboratory digital speech test facility

    NASA Astrophysics Data System (ADS)

    Tierney, J.; Schecter, H.

    1984-05-01

    A narrowband digital speech communication test facility has been established and operates between Lincoln Laboratory and the Wright-Patterson Aerospace Medical Research Laboratory. Noise fields simulating the acoustic environments of E3A and F-15 aircraft are established and Air Force personnel use the link operating at 2400 bps with a vocoder designed at Lincoln Laboratory, and a commercial telephone line modem. The facility includes a digital signal processing computer which can introduce bit errors and delay into the transmit and receive data. Communication scenarios are used to exercise the vocoder-modem channel with the dynamics and vocabulary of typical operational exchanges. Answers to a standard questionnaire provide acceptability data for the 2400 bps JTIDS class 2 voice channel. For the tests run so far, the 2400 bps voice is acceptable in the sense of positive user response to the questionnaire. Further testing using error and delay simulations will follow. An F-15 to F-15 link will be simulated at AMRL using a pair of vocoders operating back-to-back and in separate noise chambers.

  7. Using online instruction and virtual laboratories to teach hemostasis in a medical laboratory science program.

    PubMed

    Conway-Klaassen, Janice M; Wiesner, Stephen M; Desens, Christopher; Trcka, Phyllis; Swinehart, Cheryl

    2012-01-01

    Hemostasis laboratory testing methods have changed significantly over the past decades, from totally manual, to fully automated methodologies. Most medical laboratory educators prefer to use manual or semiautomated methods to teach hemostasis so that students can "see" what is occurring during the testing method, but many semi-automated instruments are no longer commercially available or are not cost-effective for education programs. In consideration of these factors and due to programmatic expansion to a coordinate campus, the CLS program explored new ways to teach hemostasis methods equitably and affordably across two distant locations. Working with an instructional design team versed in online education, five virtual hemostasis laboratory exercises were created that mimic the manual methodologies. Web-based didactic instruction was also developed to teach the testing theory and pathophysiology related to patient results. The efficacy of the virtual instruction was evaluated through assessment of student performance on exam questions, professional certification scores for the platelet/hemostasis sub-category, student satisfaction surveys, and evaluation of student performance during their clinical experience. Results showed that students in the virtual delivery format performed significantly better on exam questions compared to the traditional delivery method group, but there was no significant difference in their performance on the professional certification exam. Both student and preceptor feedback have been positive on the value of the exercises for students' understanding of hemostasis.

  8. [Fundamentals of quality control systems in medical-biochemical laboratories--the role of marketing].

    PubMed

    Topić, E; Turek, S

    2000-01-01

    The basic criterion for the overall quality system in medical biochemistry laboratories concerning equipment, premises and laboratory staff in primary health care (PHC) (Regulations on quality systems and good laboratory practice of the Croatian Medical Biochemists Chamber, 1995, Regulations on categorization of medical biochemistry laboratories of the Croatian Medical Biochemists Chamber, 1996, EC4: Essential criteria for quality systems in medical laboratories. Eur J Clin Chem Clin Biochem 1997 in medical biochemical laboratories included in the First Croatia health project, Primary health care subproject, has been met by the marketing approach to the project. The equipment ensuring implementation of the complete laboratory program (NN/96), more accurate and precise analytical procedures, and higher reliability of laboratory test results compared with previous equipment, has been purchased by an international tender. Uniform technology and methods of analysis have ensured high standards of good laboratory services, yielding test results than can be transferred from primary to secondary health care level. The new equipment has improved organization between central and detached medical biochemistry laboratory units, while the high quality requirement has led to improvement in the staff structure, e.g., medical biochemists have been employed in laboratories that had previously worked without such a professional. Equipment renewal has been accompanied by proper education for all levels of PHC professionals.

  9. Environmental Assessment for Conversion of the Existing Aero Club Runway to Emergency Helipad for David Grant Medical Center Travis Air Force Base, Fairfield, California

    DTIC Science & Technology

    2010-07-01

    Travis Air Force Base, Fairfield, California Contract No. GS-10F-132K Delivery Order No. FA4427-08-F-0133 Submitted to U. S. Air Force Center for...Engineering and the Environment Travis Air Force Base, California July 2010 2485 Natomas Park Drive Suite 600 Sacramento, CA 95833 Report...Club Runway to Emergency Helipad for David Grant Medical Center Travis Air Force Base, Fairfield, California 5a. CONTRACT NUMBER 5b. GRANT NUMBER

  10. The Medical Interaction Laboratory--Multidiscipline Approach for Presentation of Principles of Physiology and Pharmacology.

    ERIC Educational Resources Information Center

    Oliver, Jack W.; Sims, Michael H.

    1979-01-01

    An interdisciplinary physiology and pharmacology course presented by the Medical Interaction Laboratory at the University of Tennessee College of Veterinary Medicine provides interaction among faculty, conserves faculty time and animal expense, and presents a coordinated laboratory experience. (BH)

  11. Medical Laboratory Services. Student's Manual. Cluster Core for Health Occupations Education.

    ERIC Educational Resources Information Center

    Williams, Catherine

    This student's manual on medical laboratory services is one of a series of self-contained, individualized materials for students enrolled in training within the allied health field. It includes competencies that are associated with the performance of skills common to several occupations in the medical laboratory. The material is intended for use…

  12. A Comparison of the Perceptions of Laboratory Directors and Medical Technology Educators Toward Career-Entry Competencies for Associate and Baccalaureate Degree Laboratory Technology Graduates.

    ERIC Educational Resources Information Center

    Buccelli, Pamela

    A study compared the perceptions of Pennsylvania laboratory directors and medical technology educators relative to career-entry competencies for associate degree medical laboratory technicians (MLTs) and baccalaureate medical technology (MT) graduates. A 55-item competency questionnaire was administered to 265 hospital laboratory directors and 40…

  13. Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

    PubMed

    Ford, Jason; Pambrun, Chantale

    2015-05-01

    Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education.

  14. [Point of view regarding traceability and measurement uncertainty in medical laboratory accreditation].

    PubMed

    Kubono, Katsuo

    2009-06-01

    International standard ISO 15189 is a tool embodying basic qualities and scientific grounds based on test results, published in 2003. The Japan Accreditation Board for Conformity Assessment (JAB) and the Japanese Committee for Clinical Laboratory Standards (JCCLS) jointly developed the accreditation scheme for medical laboratories based on the accreditation criteria of ISO 15189, and the JAB started its accreditation service in August 2005. The service is now in its fourth year. As of the end of fiscal 2008, the total number of accredited medical laboratories was 46, consisting of nine belonging to university hospitals, nine to other medical institutes, and twenty-eight commercial laboratories. ISO 15189, which ensures the quality and competence of medical laboratories, is an excellent standard, and it is hoped that it will lead to the generation of high quality medical testing data using effective management systems. Each medical laboratory requires a program for the calibration of measurement systems and examination results by tracing to SI units or referring to a natural constant or other stated reference, and an estimate of measurement uncertainty when relevant and possible. For measurements whose uncertainty cannot be estimated, all aspects of uncertainty affecting the measurements are taken into account in "fishbone diagrams". These are important for medical doctors to understand the results and decide on courses of treatment or observation. For this, medical laboratories need to ensure traceability and assess measurement uncertainty. Finally, the goal of an accredited medical laboratory is to continue "offering effective laboratory services for patient medicine and treatment, supporting the health of the nation".

  15. A professional development model for medical laboratory scientists working in the microbiology laboratory.

    PubMed

    Amerson, Megan H; Pulido, Lila; Garza, Melinda N; Ali, Faheem A; Greenhill, Brandy; Einspahr, Christopher L; Yarsa, Joseph; Sood, Pramilla K; Hu, Peter C

    2012-01-01

    The University of Texas M.D. Anderson Cancer Center, Division of Pathology and Laboratory Medicine is committed to providing the best pathology and medicine through: state-of-the art techniques, progressive ground-breaking research, education and training for the clinical diagnosis and research of cancer and related diseases. After surveying the laboratory staff and other hospital professionals, the Department administrators and Human Resource generalists developed a professional development model for Microbiology to support laboratory skills, behavior, certification, and continual education within its staff. This model sets high standards for the laboratory professionals to allow the labs to work at their fullest potential; it provides organization to training technologists based on complete laboratory needs instead of training technologists in individual areas in which more training is required if the laboratory needs them to work in other areas. This model is a working example for all microbiology based laboratories who want to set high standards and want their staff to be acknowledged for demonstrated excellence and professional development in the laboratory. The PDM model is designed to focus on the needs of the laboratory as well as the laboratory professionals.

  16. Aero-optimum hovering kinematics.

    PubMed

    Nabawy, Mostafa R A; Crowther, William J

    2015-08-07

    Hovering flight for flapping wing vehicles requires rapid and relatively complex reciprocating movement of a wing relative to a stationary surrounding fluid. This note develops a compact analytical aero-kinematic model that can be used for optimization of flapping wing kinematics against aerodynamic criteria of effectiveness (maximum lift) and efficiency (minimum power for a given amount of lift). It can also be used to make predictions of required flapping frequency for a given geometry and basic aerodynamic parameters. The kinematic treatment is based on a consolidation of an existing formulation that allows explicit derivation of flapping velocity for complex motions whereas the aerodynamic model is based on existing quasi-steady analysis. The combined aero-kinematic model provides novel explicit analytical expressions for both lift and power of a hovering wing in a compact form that enables exploration of a rich kinematic design space. Good agreement is found between model predictions of flapping frequency and observed results for a number of insects and optimal hovering kinematics identified using the model are consistent with results from studies using higher order computational models. For efficient flight, the flapping angle should vary using a triangular profile in time leading to a constant velocity flapping motion, whereas for maximum effectiveness the shape of variation should be sinusoidal. For both cases the wing pitching motion should be rectangular such that pitch change at stroke reversal is as rapid as possible.

  17. [Medical microbiology laboratories in Dutch hospitals: essential for safe patient care].

    PubMed

    Bonten, M J M

    2008-12-06

    The Netherlands Health Care Inspectorate investigated the quality of medical microbiology laboratories in Dutch hospitals. By and large the laboratories fulfilled the requirements for appropriate care, although some processes were unsatisfactory and some were insufficiently formalised. In the Netherlands, laboratories for medical microbiology are integrated within hospitals and medical microbiologists are responsible for the diagnostic processes as well as for co-treatment of patients, infection prevention and research. This integrated model contrasts to the more industrialised model in many other countries, where such laboratories are physically distinct from hospitals with a strong focus on diagnostics. The Inspectorate also concludes that the current position of medical microbiology in Dutch hospitals is necessary for patient safety and that outsourcing of these facilities is considered unacceptable.

  18. Competency assessment of microbiology medical laboratory technologists in Ontario, Canada.

    PubMed

    Desjardins, Marc; Fleming, Christine Ann

    2014-08-01

    Accreditation in Ontario, Canada, requires that licensed clinical laboratories participate in external quality assessment (also known as proficiency testing) and perform competency evaluation of their staff. To assess the extent of ongoing competency assessment practices, the Quality Management Program--Laboratory Services (QMP-LS) Microbiology Committee surveyed all 112 licensed Ontario microbiology laboratories. The questionnaire consisted of a total of 21 questions that included yes/no, multiple-choice, and short-answer formats. Participants were asked to provide information about existing programs, the frequency of testing, what areas are evaluated, and how results are communicated to the staff. Of the 111 responding laboratories, 6 indicated they did not have a formal evaluation program since they perform only limited bacteriology testing. Of the remaining 105 respondents, 87% perform evaluations at least annually or every 2 years, and 61% include any test or task performed, whereas 16% and 10% focus only on problem areas and high-volume complex tasks, respectively. The most common methods of evaluation were review of external quality assessment (EQA) challenges, direct observation, and worksheet review. With the exception of one participant, all communicate results to staff, and most take remedial action to correct the deficiencies. Although most accredited laboratories have a program to assess the ongoing competency of their staff, the methods used are not standardized or consistently applied, indicating that there is room for improvement. The survey successfully highlighted potential areas for improvement and allowed the QMP-LS Microbiology Committee to provide guidance to Ontario laboratories for establishing or improving existing microbiology-specific competency assessment programs.

  19. Job Analysis Techniques for Restructuring Health Manpower Education and Training in the Navy Medical Department. Attachment 9. Laboratory QPCB Task Sort for Medical Laboratory Technology.

    ERIC Educational Resources Information Center

    Technomics, Inc., McLean, VA.

    This publication is Attachment 9 of a set of 16 computer listed QPCB task sorts, by career level, for the entire Hospital Corps and Dental Technician fields. Statistical data are presented in tabular form for a detailed listing of job duties in medical laboratory technology. (BT)

  20. Color blindness defect and medical laboratory technologists: unnoticed problems and the care for screening.

    PubMed

    Dargahi, Hossein; Einollahi, Nahid; Dashti, Nasrin

    2010-01-01

    Color-blindness is the inability to perceive differences between some color that other people can distinguish. Using a literature search, the results indicate the prevalence of color vision deficiency in the medical profession and its on medical skills. Medical laboratory technicians and technologists employees should also screen for color blindness. This research aimed to study color blindness prevalence among Hospitals' Clinical Laboratories' Employees and Students in Tehran University of Medical Sciences (TUMS). A cross-sectional descriptive and analytical study was conducted among 633 TUMS Clinical Laboratory Sciences' Students and Hospitals' Clinical Laboratories' Employees to detect color-blindness problems by Ishihara Test. The tests were first screened with certain pictures, then compared to the Ishihara criteria to be possible color defective were tested further with other plates to determine color - blindness defects. The data was saved using with SPSS software and analyzed by statistical methods. This is the first study to determine the prevalence of color - blindness in Clinical Laboratory Sciences' Students and Employees. 2.4% of TUMS Medical Laboratory Sciences Students and Hospitals' Clinical Laboratories' Employees are color-blind. There is significant correlation between color-blindness and sex and age. But the results showed that there is not significant correlation between color-blindness defect and exposure to chemical agents, type of job, trauma and surgery history, history of familial defect and race. It would be a wide range of difficulties by color blinded students and employees in their practice of laboratory diagnosis and techniques with a potentially of errors. We suggest color blindness as a medical conditions should restrict employment choices for medical laboratory technicians and technologists job in Iran.

  1. A Thin Layer Chromatography Laboratory Experiment of Medical Importance

    ERIC Educational Resources Information Center

    Sharma, Loretta; Desai, Ankur; Sharma, Ajit

    2006-01-01

    A thin layer chromatography experiment of medical importance is described. The experiment involves extraction of lipids from simulated amniotic fluid samples followed by separation, detection, and scanning of the lecithin and sphingomyelin bands on TLC plates. The lecithin-to-sphingomyelin ratio is calculated. The clinical significance of this…

  2. History of computer-assisted data processing in the medical laboratory.

    PubMed

    Porth, A J; Lübke, B

    1996-03-01

    Computer-assisted processing of medical laboratory data started in the sixties. The earliest systems, which arose in English- and German-speaking laboratories, pointed the way for the development of laboratory data processing. The significance and evolution of the fundamental components of a laboratory information system, such as the placing of the request to the laboratory, identification of patients and samples, recording of data, quality control, plausibility control and results, are presented. The subject is given a wider perspective by the inclusion of a comprehensive (chronological) literature index.

  3. Development and Evaluation of an Interactive Electronic Laboratory Manual for Cooperative Learning of Medical Histology

    ERIC Educational Resources Information Center

    Khalil, Mohammed K.; Kirkley, Debbie L.; Kibble, Jonathan D.

    2013-01-01

    This article describes the development of an interactive computer-based laboratory manual, created to facilitate the teaching and learning of medical histology. The overarching goal of developing the manual is to facilitate self-directed group interactivities that actively engage students during laboratory sessions. The design of the manual…

  4. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY...

  5. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL...

  6. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL...

  7. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY...

  8. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY...

  9. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY...

  10. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL...

  11. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL...

  12. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL...

  13. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., laboratory tests, and other services. We may purchase medical examinations, including psychiatric and psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY...

  14. Medical microbiology: laboratory diagnosis of invasive pneumococcal disease.

    PubMed

    Werno, Anja M; Murdoch, David R

    2008-03-15

    The laboratory diagnosis of invasive pneumococcal disease (IPD) continues to rely on culture-based methods that have been used for many decades. The most significant recent developments have occurred with antigen detection assays, whereas the role of nucleic acid amplification tests has yet to be fully clarified. Despite developments in laboratory diagnostics, a microbiological diagnosis is still not made in most cases of IPD, particularly for pneumococcal pneumonia. The limitations of existing diagnostic tests impact the ability to obtain accurate IPD burden data and to assess the effectiveness of control measures, such as vaccination, in addition to the ability to diagnose IPD in individual patients. There is an urgent need for improved diagnostic tests for pneumococcal disease--especially tests that are suitable for use in underresourced countries.

  15. Lightweight Portable Plasma Medical Device - Plasma Engineering Research Laboratory

    DTIC Science & Technology

    2012-10-01

    oxides (NOx) are produced through N2 and O2 reactions [62, 63]. The production of NOx species is mainly dependent on the oxygen (O2) concentration...Federal, $812,594.00. Thiyagarajan, Magesh (Principal), "Plasma Assisted Microbial Decontamination for Food Product Processing Industries...processes and products including processing and preservation of food items such as 86 vegetables, fruits and packaged foods , medical devices and

  16. Synchrotron radiation applications in medical research at Brookhaven National Laboratory

    SciTech Connect

    Thomlinson, W.

    1997-08-01

    In the relatively short time that synchrotrons have been available to the scientific community, their characteristic beams of UV and X-ray radiation have been applied to virtually all areas of medical science which use ionizing radiation. The ability to tune intense monochromatic beams over wide energy ranges clearly differentiates these sources from standard clinical and research tools. The tunable spectrum, high intrinsic collimation of the beams, polarization and intensity of the beams make possible in-vitro and in-vivo research and therapeutic programs not otherwise possible. From the beginning of research operation at the National Synchrotron Light Source (NSLS), many programs have been carrying out basic biomedical research. At first, the research was limited to in-vitro programs such as the x-ray microscope, circular dichroism, XAFS, protein crystallography, micro-tomography and fluorescence analysis. Later, as the coronary angiography program made plans to move its experimental phase from SSRL to the NSLS, it became clear that other in-vivo projects could also be carried out at the synchrotron. The development of SMERF (Synchrotron Medical Research Facility) on beamline X17 became the home not only for angiography but also for the MECT (Multiple Energy Computed Tomography) project for cerebral and vascular imaging. The high energy spectrum on X17 is necessary for the MRT (Microplanar Radiation Therapy) experiments. Experience with these programs and the existence of the Medical Programs Group at the NSLS led to the development of a program in synchrotron based mammography. A recent adaptation of the angiography hardware has made it possible to image human lungs (bronchography). Fig. 1 schematically depicts the broad range of active programs at the NSLS.

  17. Estimating personalized risk ranking using laboratory test and medical knowledge (UMLS).

    PubMed

    Patil, Meru A; Bhaumik, Sandip; Paul, Soubhik; Bissoyi, Swarupananda; Roy, Raj; Ryu, Seungwoo

    2013-01-01

    In this paper, we introduce a Concept Graph Engine (CG-Engine) that generates patient specific personalized disease ranking based on the laboratory test data. CG-Engine uses the Unified Medical Language System database as medical knowledge base. The CG-Engine consists of two concepts namely, a concept graph and its attributes. The concept graph is a two level tree that starts at a laboratory test root node and ends at a disease node. The attributes of concept graph are: Relation types, Semantic types, Number of Sources and Symmetric Information between nodes. These attributes are used to compute the weight between laboratory tests and diseases. The personalized disease ranking is created by aggregating the weights of all the paths connecting between a particular disease and contributing abnormal laboratory tests. The clinical application of CG-Engine improves physician's throughput as it provides the snapshot view of abnormal laboratory tests as well as a personalized disease ranking.

  18. AeroMACS system characterization and demonstrations

    NASA Astrophysics Data System (ADS)

    Kerczewski, R. J.; Apaza, R. D.; Dimond, R. P.

    This The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past three years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

  19. AeroMACS System Characterization and Demonstrations

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert J.; Apaza, Rafael D.; Dimond, Robert P.

    2013-01-01

    This The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past 3 years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

  20. AeroMACS System Characterization and Demonstrations

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert J.; Apaza, Rafael D.; Dimond, Robert P.

    2013-01-01

    The Aeronautical Mobile Airport Communications System (AeroMACS) is being developed to provide a new broadband wireless communications capability for safety critical communications in the airport surface domain, providing connectivity to aircraft and other ground vehicles as well as connections between other critical airport fixed assets. AeroMACS development has progressed from requirements definition through technology definition, prototype deployment and testing, and now into national and international standards development. The first prototype AeroMACS system has been deployed at the Cleveland Hopkins International Airport (CLE) and the adjacent NASA Glenn Research Center (GRC). During the past three years, extensive technical testing has taken place to characterize the performance of the AeroMACS prototype and provide technical support for the standards development process. The testing has characterized AeroMACS link and network performance over a variety of conditions for both fixed and mobile data transmission and has included basic system performance testing and fixed and mobile applications testing. This paper provides a summary of the AeroMACS performance testing and the status of standardization activities that the testing supports.

  1. Interference of medical contrast media on laboratory testing.

    PubMed

    Lippi, Giuseppe; Daves, Massimo; Mattiuzzi, Camilla

    2014-01-01

    The use of contrast media such as organic iodine molecules and gadolinium contrast agents is commonplace in diagnostic imaging. Although there is widespread perception that side effects and drug interactions may be the leading problems caused by these compounds, various degrees of interference with some laboratory tests have been clearly demonstrated. Overall, the described interference for iodinate contrast media include inappropriate gel barrier formation in blood tubes, the appearance of abnormal peaks in capillary zone electrophoresis of serum proteins, and a positive bias in assessment of cardiac troponin I with one immunoassay. The interference for gadolinium contrast agents include negative bias in calcium assessment with ortho-cresolphthalein colorimetric assays and occasional positive bias using some Arsenazo reagents, negative bias in measurement of angiotensin converting enzyme (ACE) and zinc (colorimetric assay), as well as positive bias in creatinine (Jaffe reaction), total iron binding capacity (TIBC, ferrozine method), magnesium (calmagite reagent) and selenium (mass spectrometry) measurement. Interference has also been reported in assessment of serum indices, pulse oximetry and methaemoglobin in samples of patients receiving Patent Blue V. Under several circumstances the interference was absent from manufacturer-supplied information and limited to certain type of reagents and/or analytes, so that local verification may be advisable to establish whether or not the test in use may be biased. Since the elimination half-life of these compounds is typically lower than 2 h, blood collection after this period may be a safer alternative in patients who have received contrast media for diagnostic purposes.

  2. Live streaming video for medical education: a laboratory model.

    PubMed

    Gandsas, Alejandro; McIntire, Katherine; Palli, Guillermo; Park, Adrian

    2002-10-01

    At the University of Kentucky (UK), we applied streaming video technology to develop a webcast model that will allow institutions to broadcast live and prerecorded surgeries, conferences, and courses in real time over networks (the Internet or an intranet). We successfully broadcast a prerecorded laparoscopic paraesophageal hernia repair to domestic and international clients by using desktop computers equipped with off-the-shelf, streaming-enabled software and standard hardware and operating systems. A web-based user interface made accessing the educational material as simple as a mouse click and allowed clients to participate in the broadcast event via an embedded e-mail/chat module. Three client computers (two connected to the Internet and a third connected to the UK intranet) requested and displayed the surgical film by means of seven common network connection configurations. Significantly, no difference in image resolution was detected with the use of a connection speed faster than 128 kilobytes per second (kbps). At this connection speed, an average bandwidth of 32.7 kbps was used, and although a 15-second delay was experienced from the time of data request to data display, the surgical film streamed continuously from beginning to end at a mean rate of 14.4 frames per second (fps). The clients easily identified all anatomic structures in full color motion, clearly followed all steps of the surgical procedure, and successfully asked questions and made comments by using the e-mail/chat module while viewing the surgery. With minimal financial investment, we have created an interactive virtual classroom with the potential to attract a global audience. Our webcast model represents a simple and practical method for institutions to supplement undergraduate and graduate surgical education and offer continuing medical education credits in a way that is convenient for clients (surgeons, students, residents, others). In the future, physicians may access streaming webcast

  3. Spatial-temporal-covariance-based modeling, analysis, and simulation of aero-optics wavefront aberrations.

    PubMed

    Vogel, Curtis R; Tyler, Glenn A; Wittich, Donald J

    2014-07-01

    We introduce a framework for modeling, analysis, and simulation of aero-optics wavefront aberrations that is based on spatial-temporal covariance matrices extracted from wavefront sensor measurements. Within this framework, we present a quasi-homogeneous structure function to analyze nonhomogeneous, mildly anisotropic spatial random processes, and we use this structure function to show that phase aberrations arising in aero-optics are, for an important range of operating parameters, locally Kolmogorov. This strongly suggests that the d5/3 power law for adaptive optics (AO) deformable mirror fitting error, where d denotes actuator separation, holds for certain important aero-optics scenarios. This framework also allows us to compute bounds on AO servo lag error and predictive control error. In addition, it provides us with the means to accurately simulate AO systems for the mitigation of aero-effects, and it may provide insight into underlying physical processes associated with turbulent flow. The techniques introduced here are demonstrated using data obtained from the Airborne Aero-Optics Laboratory.

  4. The Curriculum Development Project for the Medical Laboratory Technology Program at Miami-Dade Junior College, Miami, Florida. Final Report.

    ERIC Educational Resources Information Center

    Miami-Dade Junior Coll., FL. Div. of Allied Health Studies.

    During Phase I of an Allied Health Professions Basic Improvement Grant, a five-member committee developed a curriculum for a medical laboratory technology program at Miami-Dade Junior College by: (1) defining competencies which differentiate a certified laboratory assistant from a medical laboratory technician, (2) translating expected laboratory…

  5. Sunway Medical Laboratory Quality Control Plans Based on Six Sigma, Risk Management and Uncertainty.

    PubMed

    Jairaman, Jamuna; Sakiman, Zarinah; Li, Lee Suan

    2017-03-01

    Sunway Medical Centre (SunMed) implemented Six Sigma, measurement uncertainty, and risk management after the CLSI EP23 Individualized Quality Control Plan approach. Despite the differences in all three approaches, each implementation was beneficial to the laboratory, and none was in conflict with another approach. A synthesis of these approaches, built on a solid foundation of quality control planning, can help build a strong quality management system for the entire laboratory.

  6. The development of HIV research laboratories in the Royal Thai Army Medical Department.

    PubMed

    Chuenchitra, Thippawan; Sukwit, Suchitra; Gaywee, Jariyanart; Viputtikul, Kwanjai; Eamsila, Chirapa; Tabprasit, Sutchana; de Souza, Mark; Sirisopana, Narongrid; Nitayaphan, Sorachai; Brown, Arthur E; Chuenchitra, Cheodchai

    2005-11-01

    The development of HIV research laboratories at the Armed Forces Research Institute of Medical Sciences (AFRIMS), Royal Thai Army Medical Department in supporting of HIV-1 vaccine trials in Thailand was implemented in 1991. The collaboration between AFRIMS, Royal Thai Army Medical Department, and the US Military HIV Research Program with the ultimate goal to conduct the HIV-1 vaccine trial phase III. The HIV serology lab was set up for surveillance program in military recruits. Then, there was a need to strengthen more on the existing laboratories by training personnel to cope with the confidentiality of the lab results, specimen processing and data management which are critical. Later on, the necessary laboratory for measuring of vaccine immunogenicity was developed, such as lymphoproliferation assay. Additionally, a molecular biology lab was also developed. The HIV research laboratory management must include an ability to deal with some problems, such as late specimen receiving, fluctuating of power supply, technical staffs maintained. Good laboratory practices and safety must be strictly implemented. Communication network among facilities also played an important role in HIV laboratory strengthening at AFRIMS.

  7. Resolution requirements for aero-optical simulations

    SciTech Connect

    Mani, Ali Wang Meng; Moin, Parviz

    2008-11-10

    Analytical criteria are developed to estimate the error of aero-optical computations due to inadequate spatial resolution of refractive index fields in high Reynolds number flow simulations. The unresolved turbulence structures are assumed to be locally isotropic and at low turbulent Mach number. Based on the Kolmogorov spectrum for the unresolved structures, the computational error of the optical path length is estimated and linked to the resulting error in the computed far-field optical irradiance. It is shown that in the high Reynolds number limit, for a given geometry and Mach number, the spatial resolution required to capture aero-optics within a pre-specified error margin does not scale with Reynolds number. In typical aero-optical applications this resolution requirement is much lower than the resolution required for direct numerical simulation, and therefore, a typical large-eddy simulation can capture the aero-optical effects. The analysis is extended to complex turbulent flow simulations in which non-uniform grid spacings are used to better resolve the local turbulence structures. As a demonstration, the analysis is used to estimate the error of aero-optical computation for an optical beam passing through turbulent wake of flow over a cylinder.

  8. Developing human laboratory models of smoking lapse behavior for medication screening.

    PubMed

    McKee, Sherry A

    2009-01-01

    Use of human laboratory analogues of smoking behavior can provide an efficient, cost-effective mechanistic evaluation of a medication signal on smoking behavior, with the result of facilitating translational work in medications development. Although a number of human laboratory models exist to investigate various aspects of smoking behavior and nicotine dependence phenomena, none have yet modeled smoking lapse behavior. The first instance of smoking during a quit attempt (i.e. smoking lapse) is highly predictive of relapse and represents an important target for medications development. Focusing on an abstinence outcome is critical for medication screening as the US Food and Drug Administration approval for cessation medications is contingent on demonstrating effects on smoking abstinence. This paper outlines a three-stage process for the development of a smoking lapse model for the purpose of medication screening. The smoking lapse paradigm models two critical features of lapse behavior: the ability to resist the first cigarette and subsequent ad libitum smoking. Within the context of the model, smokers are first exposed to known precipitants of smoking relapse (e.g. nicotine deprivation, alcohol, stress), and then presented their preferred brand of cigarettes. Their ability to resist smoking is then modeled and once smokers 'give in' and decide to smoke, they participate in a tobacco self-administration session. Ongoing and completed work developing and validating these models for the purpose of medication screening is discussed.

  9. Report of the Howard Hughes Medical Institute's workshop on the performance of laboratory chemical hoods.

    PubMed

    DiBerardinis, Louis J; First, Melvin W; Party, Esmeralda; Smith, Thomas C; Warfield, Cheryl A; Carpenter, J Patrick; Cook, J Lindsay; Walters, Douglas B; Flynn, Michael R; Galson, Edgar L; Greenley, Pamela L; Hitchings, Dale T; Knutson, Gerhard W; Price, John M; Baum, Janet S; Burton, Jeff D; Finucane, Matthew D; Ghidoni, Daniel A; Koenigsberg, Jerry; Lyons, Mark; Memarzadeh, Farhad; Norton, David C; Schuyler, Glen; Zboralski, Jon; Barkley, W Emmett

    2003-01-01

    The Howard Hughes Medical Institute sponsored a workshop on laboratory chemical hoods on June 8, 9, and 10, 1998, that brought together 24 experts in the field of laboratory chemical hoods to critically assess the information known about hood performance. Workshop participants developed 31 consensus statements that reflect their collective views on the body of knowledge or lack thereof, for laboratory chemical hoods. The consensus statements fall into four broad categories: (1) hood selection, use, and operation; (2) hood and laboratory design issues; (3) ventilation system design issues; and (4) hood performance testing. The consensus statements include 26 statements on what is known and unknown about the performance of laboratory chemical hoods, 2 statements of definition, and 3 statements that reflect the participants' agreement not to agree. The brief commentary that follows each consensus statement provides guidance and recommendations.

  10. Medical Laboratory Technician--Hematology, Serology, Blood Banking, and Immunohematology (AFSC 90470).

    ERIC Educational Resources Information Center

    Thompson, Joselyn H.

    This three-volume student text is designed for use by Air Force personnel enrolled in a self-study extension course for medical laboratory technicians. Covered in the individual volumes are hematology (the physiology of blood, complete blood counts and related studies, erythrocyte studies, leukocyte and thrombocyte maturation, and blood…

  11. Military Curricula for Vocational & Technical Education. Medical Laboratory Specialist (Basic) Part I, 10-14.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    These instructor plans of instruction, lesson plans, and student text and review materials for a secondary-postsecondary-level course for medical laboratory specialist are one of a number of military-developed curriculum packages selected for adaptation to vocational instruction and curriculum development in a civilian setting. It is the first of…

  12. Military Curricula for Vocational & Technical Education. Medical Laboratory Specialist (Basic) Part II, 10-15.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    These instructor plans of instruction and lesson plans and student text and review materials for a secondary-postsecondary-level course for medical laboratory specialist are one of a number of military-developed curriculum packages selected for adaptation to vocational instruction and curriculum development in a civilian setting. It is the second…

  13. Allied Health Occupations II. Medical Laboratory Assistant Component. Student Learning Guide. Middletown Public Schools Curriculum Standards.

    ERIC Educational Resources Information Center

    Middletown Public Schools, CT.

    This volume outlines the requirements and content of a second-year course in allied health occupations education that is intended to provide students with a practical understanding of the work done by medical laboratory technicians and technologists. Addressed in the individual units of the course are the following topics: the value of…

  14. Medical Laboratory Technician--Microbiology, 10-3. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This course, the second of three courses in the medical laboratory technician field adapted from military curriculum materials for use in vocational and technical education, was designed as a refresher course for student self-study and evaluation. It is suitable for use by advanced students or beginning students participating in a supervised…

  15. A Needs Assessment of the Medical Laboratory Technology Students at New York City Technical College.

    ERIC Educational Resources Information Center

    Selvadurai, Ranjani

    A study examined the needs of medical laboratory technology students at New York City Technical College. The nominal group technique (which involves silent generation of ideas in writing, round-robin feedback, and individual voting on priority ideas) was used to assess the academic and personal needs of 20 students. The following seven significant…

  16. [Role and future aspects of hospital clinical laboratories in medical team approaches].

    PubMed

    Suwabe, Akira

    2011-09-01

    The recent progress in medicine increases the routine works of the physicians or nurses and decreases the chances to obtain the new information on the laboratory medicine. Although the patients desire to know their test results in detail, it is likely to be difficult to obtain them from the physician in charge. Thereby, the quality of the medical services may be deteriorated. In these situations, needs of the medical team approaches in which the medical technologists (MTs) in the hospital laboratories participate are increasing. In Japan, there are a variety of medical team approaches in which MTs are involved. In our university hospital, MTs play important roles in the infection control team (ICT), in the nutrition support team (NST), in the educational class for the patients with diabetes mellitus, in the clinical research center, in the order-made medicine realizing project, in the infertility center and in the laboratory information room. In April 2010, the new payment system for the team approaches such as ICT or NST was established. In the future, the team approaches other than ICT or NST could be chosen for the subjects for the payment if they are recognized as important. The goal of the team approaches is to realize a patient-oriented medicine. MTs can reconfirm that they are working as one of the medical staffs through these team approaches. It is important to always find out a possibility of new team approaches.

  17. [A Perspective on Innovation for Efficient Medical Practice in View of Undergraduate and Postgraduate Education and Training in Laboratory Medicine].

    PubMed

    Kawai, Tadashi

    2015-10-01

    Continuous advances in medical laboratory technology have driven major changes in the practice of laboratory medicine over the past two decades. The importance of the overall quality of a medical laboratory has been ever-increasing in order to improve and ensure the quality and safety of clinical practice by physicians in any type of medical facility. Laboratory physicians and professional staff should challenge themselves more than ever in various ways to cooperate and contribute with practicing physicians for the appropriate utilization of laboratory testing. This will certainly lead to a decrease in inappropriate or unnecessary laboratory testing, resulting in reducing medical costs. In addition, not only postgraduate, but also undergraduate medical education/training systems must be markedly innovated, considering recent rapid progress in electronic information and communication technologies.

  18. A Competency-Based Clinical Chemistry Course for the Associate Degree Medical Laboratory Technician Graduate in a Medical Technology Baccalaureate Program.

    ERIC Educational Resources Information Center

    Buccelli, Pamela

    Presented is a project that developed a competency-based clinical chemistry course for associate degree medical laboratory technicians (MLT) in a medical technology (MT) baccalaureate program. Content of the course was based upon competencies expected of medical technologists at career-entry as defined in the statements adopted in 1976 by the…

  19. Recommendation for the review of biological reference intervals in medical laboratories.

    PubMed

    Henny, Joseph; Vassault, Anne; Boursier, Guilaine; Vukasovic, Ines; Mesko Brguljan, Pika; Lohmander, Maria; Ghita, Irina; Andreu, Francisco A Bernabeu; Kroupis, Christos; Sprongl, Ludek; Thelen, Marc H M; Vanstapel, Florent J L A; Vodnik, Tatjana; Huisman, Willem; Vaubourdolle, Michel

    2016-12-01

    This document is based on the original recommendation of the Expert Panel on the Theory of Reference Values of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), updated guidelines were recently published under the auspices of the IFCC and the Clinical and Laboratory Standards Institute (CLSI). This document summarizes proposals for recommendations on: (i) The terminology, which is often confusing, noticeably concerning the terms of reference limits and decision limits. (ii) The method for the determination of reference limits according to the original procedure and the conditions, which should be used. (iii) A simple procedure allowing the medical laboratories to fulfill the requirements of the regulation and standards. The updated document proposes to verify that published reference limits are applicable to the laboratory involved. Finally, the strengths and limits of the revised recommendations (especially the selection of the reference population, the maintenance of the analytical quality, the choice of the statistical method used…) will be briefly discussed.

  20. Staphylococcus aureus with Panton-Valentine toxin skin infection in a medical laboratory technician.

    PubMed

    Pougnet, Richard; Pougnet, Laurence

    2016-12-01

    This report exposes the case of a Staphylococcus aureus infection occurring in a microbiology laboratory technician. He was a 52 year-old man without medical history. He presented an abscess on the anterior aspect of the left forearm. Analysis showed that it was a Staphylococcus aureus secreting the Panton-Valentine toxin. The study of the workplace found the frequency of exposure. The study of workstation showed the link between the technician position and the infection. Indeed, this man touched an area where the biocleaning was hard to do. This is the first case of infection with PVL described for a laboratory technician.

  1. The Impact of an Electronic Medical Record on Repeat Laboratory Test Ordering Across Four Australian Hospitals.

    PubMed

    Georgiou, Andrew; Vecellio, Elia; Li, Ling; Westbrook, Johanna I

    2015-01-01

    In this study we examined the impact of an Electronic Medical Record (EMR) on repeat test rates (i.e., the same test ordered within a specified window of time) for a commonly ordered set of laboratory tests; Electrolytes, Urea, Creatinine [EUC], Full Blood Counts [FBC] and Liver Function Tests [LFT]. The results point to the potential that timely, evidence-based electronic decision support features can have on the efficiency and effectiveness of the pathology laboratory process and its contribution to quality patient care.

  2. Awareness and Knowledge of Ergonomics Among Medical Laboratory Scientists in Nigeria

    PubMed Central

    Oladeinde, BH; Ekejindu, IM; Omoregie, R; Aguh, OD

    2015-01-01

    Background: Ergonomics awareness helps in its right application and contributes significantly to general wellbeing and safety of worker at workplace. Aim: This cross-sectional descriptive study aimed at assessing the level of awareness and knowledge of the science of ergonomics among Medical Laboratory Scientists in Benin City, Nigeria. Subjects and Methods: A total of 106 medical laboratory scientists comprising 64 and 42 in public and private laboratories, respectively, were recruited for this study using systematic random sampling technique. Data were obtained from the study participants using a questionnaire and subsequently analyzed with the statistical software INSTAT®. Results: Out of 106 study participants, 27 (25.5%) were reported to have heard of the term ergonomics. Awareness was significantly associated with gender (male vs. female: 38.5% [15/39] vs. 17.9% [12/67]; odds ratio = 2.9; 95% confidence interval = 1.2, 7.1;P = 0.02). Awareness of ergonomics was not significantly affected by affiliation (P = 0.18), area of specialization (P = 0.78), post-qualification experience (P = 0.43), and educational qualification (P = 0.23) of the study participants. Irrespective of the affiliation of the participant, only 6 of 27 (22.2%) participants who were aware of ergonomics knew at least a benefit of right application of ergonomics in the laboratory. Knowledge of risk factors for the development of musculoskeletal disorders was reported by 8 of 27 (29.6%) persons who claimed to be aware of ergonomics. Conclusions: Awareness of ergonomics and knowledge of gains of its right application was poor among the study participants. Regular ergonomic education of medical laboratory scientists in Nigeria is advocated. PMID:27057381

  3. Giving feedback in medical teaching: a case of lung function laboratory/spirometry.

    PubMed

    Meo, Sultan Ayoub

    2013-01-01

    Feedback in medical teaching is an important part of medical education, it encourages and enhances the learners' knowledge, skills and professional performance at various stages of their schooling. A constructive feedback enhances the awareness of strength and areas for improvement. An adequate, meaningful and fruitful feedback needs motivation, emphasis, objectivity, expertise, and active participation in the session. Before giving feedback, the instructor should be well prepared and must have practice on the task. The instructor should utilize all means such as good oral presentation, eye contact, visual cues, utilize body language to actively involve the learners in a session, all these activities enhance the knowledge, skill and attitude of the learners. The aim of this commentary is to highlight the basic issues in giving an appropriate feedback in medical teaching with special emphasis on a lung function laboratory / Spirometry.

  4. Keeping the culture alive: the laboratory technician in mid-twentieth-century British medical research

    PubMed Central

    Tansey, E.M.

    2008-01-01

    This paper reports results from a detailed study of the careers of laboratory technicians in British medical research. Technicians and their contributions are very frequently missing from accounts of modern medicine, and this project is an attempt to correct that absence. The present paper focuses almost entirely on the Medical Research Council's National Institute for Medical Research in North London, from the first proposal of such a body in 1913 until the mid 1960s. The principal sources of information have been technical staff themselves, largely as recorded in an extensive series of oral history interviews. These have covered a wide range of issues and provide valuable perspectives about technicians' backgrounds and working lives. PMID:18548906

  5. [The practice of development and implementation of quality management systems in medical laboratories. The GOST R ISO 15189-2009 "medical laboratories. The detailed requirements to quality and competence". Particular difficulties of global nature].

    PubMed

    Emanuel', A V; Ivanov, G A; Fleganova, I N; Emanuel', V L

    2012-12-01

    The article discusses the methodological issues related to the implementation of international principles of standardization in the format of GOST R ISO 9001-2008 "Quality management systems. Requirements", GOST R ISO 15189-2009 "Medical laboratories. The detailed requirements to quality and competence" and GOST R ISO 18113.1-5 "Medical items for diagnostics in vitro. Information provided by manufacturer (marking)". This approach legibly assigns the responsibility concerning the support of metrological correctness of laboratory measurements. The lacking of both full-value public and sectorial normative documentation and coordinated positions of Rosstandard and Minzdrav of Russia on functioning of medical laboratories is noted.

  6. Developing a theory of clinical instructor identity using the experiences of medical laboratory science practitioners.

    PubMed

    Miller, Wendy

    2014-01-01

    This study investigated medical laboratory science clinical instructors' beliefs about teaching and how they viewed themselves as teachers. The first phase of the study included an integrative literature review, which suggested that the development of teacher identity in school-based educators, and to a lesser extent higher education faculty, is dependent on four dimensions: personal factors, training factors, contextual factors, and reflective practice. The second phase of this study began qualitative inquiry into the ways that these participants described their teaching and professional identity. Interviews were conducted with medical laboratory science clinical instructors in order to gain an understanding of their perceptions of themselves as teachers. The data collected in this study indicate that this group of clinical instructors saw themselves as teachers who were responsible for providing students with technical skills needed to become competent practitioners and the theoretical foundation necessary to pass the national certification exam. The study participants also saw themselves as mentors who were responsible for passing along professional knowledge to the next generation of laboratory practitioners. During data analysis three themes emerged that represent aspects of teacher identity in clinical instructors: belief in one's teaching ability, desire to expand one's professional responsibilities, and reflection on one's teaching. The findings from this study may provide a foundation for future research designed to measure teacher identity in clinical instructors.

  7. Perceptions of a medical microbiology service: a survey of laboratory users.

    PubMed Central

    Morgan, M S

    1995-01-01

    AIM--To ascertain the perception of laboratory users regarding the quality of the medical microbiology services in a district general hospital. METHODS--Detailed questionnaires were circulated to all clinicians in the locality, with headings covering the quality of medical advice provided, the availability of information on specimen collection, format of request forms, specimen transport arrangements, turnaround times, the quality and need for interpretative advice, and the overall impression of the quality of the services provided. RESULTS--Two hundred and thirty five replies were received, giving a response rate of 69%. Transportation of specimens and communication of reports were identified as priority areas for improvement. The overall quality of the service was perceived as satisfactory, although areas were identified where substantial improvements could be made, some at little or no cost to the laboratory. CONCLUSIONS--The survey focused clinicians' attention on the service, raised the profile of the laboratory, and resulted in improved communications and a better understanding of customer needs. Overall, the exercise was felt to be extremely useful, and worthwhile repeating to gauge the effect of the changes instituted as a result. PMID:8537489

  8. Results of the AEROS satellite program: Summary

    NASA Technical Reports Server (NTRS)

    Lammerzahl, P.; Rawer, K.; Roemer, N.

    1980-01-01

    Published literature reporting aeronomic data collected on two AEROS missions is summarized. The extreme ultraviolet solar radiation and other significant parameters of the thermosphere/ionosphere were investigated. Kinetic pressure, the quantity of atomic nitrogen, and partial densities of helium, oxygen, nitrogen, argon, and atomic nitrogen were determined. The thermal electron population, superthermal energy distribution, plasma density, ion temperature, and composition according to ion types were measured. The chief energy supply in the thermosphere was calculated. Aeronomic calculations showing that variations in the parameters of the ionosphere cannot be correlated with fluctuations of extreme ultraviolet solar radiation were performed. The AEROS data were compared with data from S3-1, ISIS, and AE-C satellites. Models of the thermosphere and ionosphere were developed.

  9. Transient aero-thermal simulations for TMT

    NASA Astrophysics Data System (ADS)

    Vogiatzis, Konstantinos

    2014-08-01

    Aero-thermal simulations are an integral part of the design process for the Thirty Meter Telescope (TMT). These simulations utilize Computational Solid-Fluid Dynamics (CSFD) to estimate wind jitter and blur, dome and mirror seeing, telescope pointing error due to thermal drift, and to predict thermal effects on performance of components such as the primary mirror segments. Design guidance obtained from these simulations is provided to the Telescope, Enclosure, Facilities and Adaptive Optics groups. Computational advances allow for model enhancements and inclusion of phenomena not previously resolved, such as transient effects on wind loading and thermal seeing due to vent operation while observing or long exposure effects, with potentially different flow patterns corresponding to the beginning and end of observation. Accurate knowledge of the Observatory aero-thermal environment will result in developing reliable look-up tables for effective open loop correction of key active optics system elements, and cost efficient operation of the Observatory.

  10. Development and Validation of a New Blade Element Momentum Skewed-Wake Model within AeroDyn: Preprint

    SciTech Connect

    Ning, S. A.; Hayman, G.; Damiani, R.; Jonkman, J.

    2014-12-01

    Blade element momentum methods, though conceptually simple, are highly useful for analyzing wind turbines aerodynamics and are widely used in many design and analysis applications. A new version of AeroDyn is being developed to take advantage of new robust solution methodologies, conform to a new modularization framework for National Renewable Energy Laboratory's FAST, utilize advanced skewed-wake analysis methods, fix limitations with previous implementations, and to enable modeling of highly flexible and nonstraight blades. This paper reviews blade element momentum theory and several of the options available for analyzing skewed inflow. AeroDyn implementation details are described for the benefit of users and developers. These new options are compared to solutions from the previous version of AeroDyn and to experimental data. Finally, recommendations are given on how one might select from the various available solution approaches.

  11. Students' responses to the introduction of a digital laboratory guide in medical neuroscience.

    PubMed

    Brueckner, Jennifer K; Traurig, Harold

    2003-11-01

    This study investigated student acceptance of a digital laboratory guide in a medical neuroscience course. The guide was created in Macromedia Authorware 5.2 by transforming a text-based lab manual into a comprehensive multimedia program. Student attitudinal survey data indicated that the guide was used primarily as a study tool at home. Some 53% of students (primarily males) used the guide for independent study exclusively, while the remainder used it for both independent and group study; 87% of the class used the guide as a routine study tool rather than as a final review for examinations. Most students perceived that the guide increased their study efficiency and lab performance while decreasing their out-of-class study time in the lab. Female students were significantly more enthusiastic about the guide's impact on their study efficiency, lab performance and laboratory study time. Gender differences in student satisfaction with and use of instructional multimedia are discussed.

  12. An effective training program for chest tube drainage for medical interns in a clinical simulation laboratory.

    PubMed

    Yoshimura, Akinobu; Kosaihira, Seiji; Morimoto, Taisuke; Kim, Chol; Tsueshita, Takaya; Adachi, Kohji; Aso, Ryoko; Shimura, Toshiro; Nakano, Hiroshi; Gemma, Akihiko

    2012-01-01

    The Department of Respiratory Medicine of Nippon Medical School Hospital and the Working Committee of Clinical Simulation Laboratory have held training sessions for chest tube drainage since 2007. The training program consists of the preparation of a training manual, a small-group session, and a review of the process of chest tube drainage using a checklist of steps after the session. A total of 21 medical interns of Nippon Medical School Hospital participated in training sessions from April 2010 through February 2011. A questionnaire survey at the end of the session revealed that most participants rated highly both the explanations given by the instructors and the descriptions in the manual for comprehensibility. Only 3 interns felt that they had successfully acquired the clinical skill, and the other 18 interns felt that they had somewhat acquired the skill. Research after the interns had completed the program of the department showed that 80% of interns had performed chest tube drainage for patients during the rotation. The interns assessed the training program as useful, and some interns felt they could perform the skill with confidence or without anxiety. Other systematic programs of skill training for medical interns are recommended to ensure definite acquisition of basic skills.

  13. How accurate are electronic monitoring devices? A laboratory study testing two devices to measure medication adherence.

    PubMed

    De Bleser, Leentje; De Geest, Sabina; Vandenbroeck, Sofie; Vanhaecke, Johan; Dobbels, Fabienne

    2010-01-01

    In a prospective descriptive laboratory study, 25 Helping Hand(™) (HH) (10 without and 15 with reminder system) and 50 Medication Event Monitoring Systems (MEMS) (25 with 18-month and 25 with 2-year battery life) were manipulated twice daily following a predefined protocol during 3 consecutive weeks. Accuracy was determined using the fixed manipulation scheme as the reference. Perfect functioning (i.e., total absence of missing registrations and/or overregistrations) was observed in 70% of the HH without, 87% of the HH with reminder, 20% MEMS with 18 months, and 100% with 2-year battery life respectively.

  14. Preparing the next generation of genomicists: a laboratory-style course in medical genomics.

    PubMed

    Linderman, Michael D; Bashir, Ali; Diaz, George A; Kasarskis, Andrew; Sanderson, Saskia C; Zinberg, Randi E; Mahajan, Milind; Shah, Hardik; Suckiel, Sabrina; Zweig, Micol; Schadt, Eric E

    2015-08-12

    The growing gap between the demand for genome sequencing and the supply of trained genomics professionals is creating an acute need to develop more effective genomics education. In response we developed "Practical Analysis of Your Personal Genome", a novel laboratory-style medical genomics course in which students have the opportunity to obtain and analyze their own whole genome. This report describes our motivations for and the content of a "practical" genomics course that incorporates personal genome sequencing and the lessons we learned during the first three iterations of this course.

  15. Development and evaluation of an interactive electronic laboratory manual for cooperative learning of medical histology.

    PubMed

    Khalil, Mohammed K; Kirkley, Debbie L; Kibble, Jonathan D

    2013-01-01

    This article describes the development of an interactive computer-based laboratory manual, created to facilitate the teaching and learning of medical histology. The overarching goal of developing the manual is to facilitate self-directed group interactivities that actively engage students during laboratory sessions. The design of the manual includes guided instruction for students to navigate virtual slides, exercises for students to monitor learning, and cases to provide clinical relevance. At the end of the laboratory activities, student groups can generate a laboratory report that may be used to provide formative feedback. The instructional value of the manual was evaluated by a questionnaire containing both closed-ended and open-ended items. Closed-ended items using a five-point Likert-scale assessed the format and navigation, instructional contents, group process, and learning process. Open-ended items assessed student's perception on the effectiveness of the manual in facilitating their learning. After implementation for two consecutive years, student evaluation of the manual was highly positive and indicated that it facilitated their learning by reinforcing and clarifying classroom sessions, improved their understanding, facilitated active and cooperative learning, and supported self-monitoring of their learning.

  16. Ordering patterns for laboratory and radiology tests by students from different undergraduate medical curricula

    PubMed Central

    2013-01-01

    Background The overuse of laboratory tests and radiology imaging and their possible hazards to patients and the health care system is observed with growing concern in the medical community. With this study the authors wished to determine whether ordering patterns for laboratory and radiology tests by medical students close to their graduation are related to undergraduate training. Methods We developed an assessment for near graduates in the setting of a resident’s daily routine including a consultation hour with five simulated patients, three hours for patient work up with simulated distracting tasks, and thirty minutes for reporting of patient management to a supervisor. In 2011, 60 students participated in this assessment: 30 from a vertically integrated (VI) curriculum (Utrecht, The Netherlands) and 30 from a traditional, non-VI curriculum (Hamburg, Germany). We assessed and compared the number of laboratory and radiology requests and correlated the results with the scores participants received from their supervisors for the facet of competence “scientifically and empirically grounded method of working”. Results Students from a VI curriculum used significantly (p < .01) less total laboratory requests (N = 283 versus N = 466) which correlated with their scores for a “scientifically and empirically grounded method of working” (Pearson’s r = .572). A significantly (p < .01) higher number of radiology imaging was ordered with a large effect size (V = .618) by near graduates from a non-VI curriculum (N = 156 versus N = 97) even when this was not supporting the diagnostic process. Conclusion The focused ordering patterns from VI students might be a result of their early exposure to the clinical environment and a different approach to clinical decision making during their undergraduate education which further studies should address in greater detail. PMID:23945311

  17. [Consulting work cited in the hospital laboratory annual progress report of the laboratory information and consulting work and its role in Toyama Medical and Pharmaceutical University Hospital].

    PubMed

    Yamaguchi, Keiji; Tanaka, Yoko; Takamori, Eiko; Kitajima, Isao

    2005-07-01

    Recently, it is difficult for general patients to understand clinical inspection. Therefore we opened the laboratory information and consulting office (called Kensa Yorozu Consulting Room) from April, 2004. It is most characteristic that our office is managed by a clinical laboratory physician. A full time-specialized doctor who is belong to clinical laboratory, is stationed in the office. Duties contents of our office are consultation, publishing laboratory report and information, education and the clinical studies. We don't limit a person of consultation in particular. We accept consultations for 24 hours by coming our office, telephone, Fax or E-mail. The amount of consultations is about 5-10 per one month. The contents are suggesting inspection plan, explanation of pathophysiologic information based on clinical inspect result and so on. The examples compiled it into a database and maintains and their answers information. Because there are clinical laboratory physicians in this office, there are merits that follow. As for the medical technologist, it was not interfered with routine duties. For doctors and co-medical staffs, it is possible for detailed arguments to the diagnosis and treatment considered the condition of a patient and a characteristic of laboratory method. Doctors of outside can talk with us by telephones or emails easily. For patients, they can smoothly talk about their diseases with their physicians knowing more laboratory information. More medical stuffs need our office, because there are many repeaters although the total number is small. Therefore it is important that we let everybody know about our works and that we make good communication environment to talk easily, keeping privacy. We want to compile and share database of laboratory information. Then we can contribute to the area medical care.

  18. Multilingual and Native English-Speaking Student Writers in Medical Laboratory Sciences (MLS): A Comparative Pilot Study

    ERIC Educational Resources Information Center

    Conway-Klaassen, Janice M.; Thompson, Julie M.; Eliason, Patricia A.; Collins, Molly Rojas; Murie, Robin; Spannaus-Martin, Donna J.

    2015-01-01

    Medical laboratory scientists are health care practitioners who perform testing on blood and other body fluids providing vital information to physicians for the diagnosis, treatment, and management of patients in health and disease. Miscommunications between laboratory personnel and other health care practitioners can result in unwarranted delays…

  19. [Experience of the development special medical technical laboratory for studies of effects caused by potent electromagnetic radiation in biologic objects].

    PubMed

    Gorodetsky, B N; Kalyada, T V; Petrov, S V

    2015-01-01

    This article covers topics of creating special medical technical laboratory for medial and biologic studies concerning influence of potent high-frequency elecromagnetic radiation on various biologic objects. The authors gave example of such laboratory, described its construction features, purpose and main characteristics of the included devices.

  20. Aero/fluids database system

    NASA Technical Reports Server (NTRS)

    Reardon, John E.; Violett, Duane L., Jr.

    1991-01-01

    The AFAS Database System was developed to provide the basic structure of a comprehensive database system for the Marshall Space Flight Center (MSFC) Structures and Dynamics Laboratory Aerophysics Division. The system is intended to handle all of the Aerophysics Division Test Facilities as well as data from other sources. The system was written for the DEC VAX family of computers in FORTRAN-77 and utilizes the VMS indexed file system and screen management routines. Various aspects of the system are covered, including a description of the user interface, lists of all code structure elements, descriptions of the file structures, a description of the security system operation, a detailed description of the data retrieval tasks, a description of the session log, and a description of the archival system.

  1. Water Efficiency Improvements at Various Environmental Protection Agency Sites: Best Management Practice Case Study #12 - Laboratory/Medical Equipment (Brochure)

    SciTech Connect

    Blakley, H.

    2011-03-01

    The U.S. Environmental Protection Agency (EPA) built a successful water conservation program and reduced potable water use through a series of initiatives at EPA laboratories. The projects highlighted in this case study demonstrate EPA's ability to reduce water use in laboratory and medical equipment by implementing vacuum pump and steam sterilizer replacements and retrofits. Due to the success of the initial vacuum pump and steam sterilizer projects described here, EPA is implementing similar projects at several laboratories throughout the nation.

  2. Evaluating performance in sweat testing in medical biochemistry laboratories in Croatia

    PubMed Central

    Aralica, Merica; Krleza, Jasna Lenicek

    2017-01-01

    Introduction Sweat test has a diagnostic role in evaluation of cystic fibrosis. Its performance includes sweat stimulation, collection and analysis. All listed may be sources of inconsistencies in everyday practice. The aim of this study was an evaluation of external quality assessment (EQA) of sweat chloride measurement including sweat test performance in medical biochemistry laboratories in Croatia. Materials and methods EQA for sweat chloride measurement was provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) in five consecutive exercises to medical biochemistry laboratories (MBL) that offered sweat testing. A questionnaire regarding all phases of testing was mailed to involved MBL (N = 10). Survey results were compared to current guidelines for sweat test performance. Results Reported results of EQA in 2015 exercises showed coefficients of variation (CV) from 28.9%, 29.0% to 35.3%, respectively. An introduction of uniform sweat chloride measurement protocol resulted in CV of 15.5% and 14.7% reported in following two exercises in 2016. All MBL included in this study replied to the questionnaire. Results reported by MBL indicated: lack of patient information policy (7/10), use of unacceptable electrodes (6/9), misuse of minimum of acceptable sweat weight (6/9), lack of internal quality assessment (5/9) and recommended reference ranges (5/9 and 4/9). Agreements to guidelines were found in approach to unsuitable patients (9/10) and sweat collection (8/9). Conclusion Presented results indicate major weak points of current practice in sweat test performance in Croatian MBL and stress the need for its standardization on a national level.

  3. Speeding up laboratory test reporting in Medical Emergency and Cardiac Arrest calls: a quality improvement project

    PubMed Central

    Al-Talib, Mohammed; Leslie, Isla

    2017-01-01

    Many hospitals deploy Medical Emergency (MET) and Cardiac Arrest teams to improve the management and treatment of patients who become critically ill. In many cases, blood results are key in allowing the clinicians involved in these teams to make definitive management decisions for these patients. Following anecdotal reports that these results were often delayed, we assessed the process of blood tests being reported in emergency calls, identified the key factors causing delays and sought to make improvements. The initial intervention involved implementing a new blood form that specified the nature of the call, the tests required and a contact number for laboratory staff to contact the clinical team with results. We also developed a streamlined process within the laboratory for these samples to be fast-tracked. Successive improvement cycles sought to increase awareness of the project, improve accessibility to the new forms and embed spontaneous practices that contributed to improvement. Results demonstrated an overall reduction in the time taken for blood samples in emergencies to be reported from 130 minutes to 97 minutes. This project demonstrates that using a specific blood request form for emergency calls, and tying this to a specified laboratory process, improves the time taken for these tests to be reported. In addition, the project provides some insight into challenges faced when implementing change in new departments. PMID:28243442

  4. A tracking system for laboratory mice to support medical researchers in behavioral analysis.

    PubMed

    Macrì, S; Mainetti, L; Patrono, L; Pieretti, S; Secco, A; Sergi, I

    2015-08-01

    The behavioral analysis of laboratory mice plays a key role in several medical and scientific research areas, such as biology, toxicology, pharmacology, and so on. Important information on mice behavior and their reaction to a particular stimulus is deduced from a careful analysis of their movements. Moreover, behavioral analysis of genetically modified mice allows obtaining important information about particular genes, phenotypes or drug effects. The techniques commonly adopted to support such analysis have many limitations, which make the related systems particularly ineffective. Currently, the engineering community is working to explore innovative identification and sensing technologies to develop new tracking systems able to guarantee benefits to animals' behavior analysis. This work presents a tracking solution based on passive Radio Frequency Identification Technology (RFID) in Ultra High Frequency (UHF) band. Much emphasis is given to the software component of the system, based on a Web-oriented solution, able to process the raw tracking data coming from a hardware system, and offer 2D and 3D tracking information as well as reports and dashboards about mice behavior. The system has been widely tested using laboratory mice and compared with an automated video-tracking software (i.e., EthoVision). The obtained results have demonstrated the effectiveness and reliability of the proposed solution, which is able to correctly detect the events occurring in the animals' cage, and to offer a complete and user-friendly tool to support researchers in behavioral analysis of laboratory mice.

  5. In vitro diagnostic company recalls and medical laboratory practices: an Italian case

    PubMed Central

    Lippi, Giuseppe; Salvagno, Gian Luca; Brocco, Giorgio; Guidi, Gian Cesare

    2015-01-01

    Introduction In vitro human diagnostic (IVD) company recalls are a common practice aimed to either minimize a potential error or eliminate an existing failure. In this case report, we aim to provide a critical analysis of a recent IVD recall and to provide a practical framework about what to do when an IVD company recalls product(s) based on the International Organization for Standardization - ISO 15189:2012 standard. Case report In 2014, Abbott Laboratories® (Green Oaks, IL) published an urgent field safety notice regarding a product recall (Architect Intact parathyroid hormone (PTH) Assay List Number 8K25) with immediate action required. The IVD company explained the reasons for the recall as follows: i) Abbott has confirmed that a performance shift in the Architect Intact PTH assay has the potential to generate falsely elevated results on patient samples; ii) results generated with impacted lots may demonstrate a positive shift relative to those generated with previous reagent and/or calibrator lots. This issue may also impact established Architect Intact PTH reference ranges; iii) the magnitude of shift averages approximately 13% to 45%; iv) Abbott Architect Intact PTH controls do not detect the shift; and v) all current reagent, calibrator, and control inventory are impacted. The recall could have resulted in ~40,000 inaccurate laboratory tests reported by 18 laboratories from Italy (Lombardy region). Conclusion IVD company recalls have a serious impact on the patient safety and require a thorough investigation and responsible approach to minimize the possible damage. Medical laboratories accredited according to the ISO 15189 standard have procedures in place to manage such situations and ensure that patient safety is maintained when such recalls are issued. PMID:26110040

  6. Analysis of Radiation Impact on White Mice through Radiation Dose Mapping in Medical Physics Laboratory

    NASA Astrophysics Data System (ADS)

    Sutikno, Madnasri; Susilo; Arya Wijayanti, Riza

    2016-08-01

    A study about X-ray radiation impact on the white mice through radiation dose mapping in Medical Physic Laboratory is already done. The purpose of this research is to determine the minimum distance of radiologist to X-ray instrument through treatment on the white mice. The radiation exposure doses are measured on the some points in the distance from radiation source between 30 cm up to 80 with interval of 30 cm. The impact of radiation exposure on the white mice and the effects of radiation measurement in different directions are investigated. It is founded that minimum distance of radiation worker to radiation source is 180 cm and X-ray has decreased leukocyte number and haemoglobin and has increased thrombocyte number in the blood of white mice.

  7. Aero-thermal modeling framework for TMT

    NASA Astrophysics Data System (ADS)

    Vogiatzis, Konstantinos

    2011-09-01

    The Performance Error Budget of the Thirty Meter Telescope (TMT) suggests that nearly one third of the total image degradation is due to aero-thermal disturbances (mirror and dome seeing, dynamic wind loading and thermal deformations of the optics, telescope structure and enclosure). An update of the current status of aero-thermal modeling and Computational Fluid-Solid Dynamics (CFSD) simulations for TMT is presented. A fast three-dimensional transient conduction-convection-radiation bulk-air-volume model has also been developed for the enclosure and selected telescope components in order to track the temperature variations of the surfaces, structure and interstitial air over a period of three years using measured environmental conditions. It is used for Observatory Heat Budget analysis and also provides estimates of thermal boundary conditions required by the CFD/FEA models and guidance to the design. Detailed transient CFSD conjugate heat transfer simulations of the mirror support assemblies determine the direction of heat flow from important heat sources and provide guidance to the design. Finally, improved CFD modeling is used to calculate wind forces and temperature fields. Wind loading simulations are demonstrated through TMT aperture deflector forcing. Temperature fields are transformed into refractive index ones and the resulting Optical Path Differences (OPDs) are fed into an updated thermal seeing model to estimate seeing performance metrics. Keck II simulations are the demonstrator for the latter type of modeling.

  8. [Education for medical students and post-graduates--Training of laboratory medicine at Nihon University Medical School and Surugadai Nihon University Hospital].

    PubMed

    Tsuchiya, Tatsuyuki

    2011-09-01

    Laboratory medicine is defined as 'a field which analyzes the patients' clinical condition and contributes to the procedures such as diagnosis, treatment, follow-up, and prognostic determination'. In other words, it involves not only in every process of medical treatment for patients, but also in the field of preventive medicine and occupational health. Therefore, it is unavoidable for every department to interpret the laboratory data. This necessarily requires all medical students to master laboratory test procedures, comprehend various impediments to the accurate laboratory data, and acquire the basics of the interpretation of laboratory data. During postgraduate training period, they must acquire enough skill of test procedures and determination methods such as Gram stain, and their interpretation of the test results should also be wide and directly connected to the treatment. Physicians who are trained in each particular department and aim to become a laboratory physician are in need of enough understanding of the specialized tests relate to each specialized area. Based on the fact that laboratory physicians involve in all of these educations, this symposium addresses the early training during pre- and post-graduation in Nihon University.

  9. Diagnosing Malaria Cases Referred to the Malaria Reference Laboratory in Tehran University of Medical Science, Iran

    PubMed Central

    NATEGHPOUR, Mehdi; EDRISSIAN, Gholamhossein; MOTEVALLI HAGHI, Afsaneh; FARIVAR, Leila; KAZEMI-RAD, Elham

    2015-01-01

    Background: The number of malaria cases is declining worldwide; however, it remains as a serious health problem. Diagnosing unusual cases is the most important issue to manage the problem. This study designed to describe the number of falciparum and vivax malaria infected patients referred to Malaria Reference Laboratory in Tehran University of Medical Science from 2000 to 2012. Methods: A retrospective study was conducted based on the collected questionnaires from each patient referred to the laboratory. Diagnosing results and demographic information for positive cases were analyzed using SPSS software. Problematic cases were evaluated for any difficulties in diagnosis or in clinical signs. Scanning and molecular methods were performed whenever there was an atypical case referred to the laboratory. Some of the samples had various difficulties for diagnosing such as presence of fussed gametocytes and schizonts of Plasmodium falciparum in peripheral blood and CCHF like hemoragic disorders. Results: Plasmodium vivax caused a large proportion of the cases (76.1%) in contrast with P. falciparum that included smaller proportion (22.8%) and the rest (1.1) belonged to mixed infection. Most of the positive cases (69.6%) were belonged to Afghani people. Men (94.6%) showed more infection than women (5.4%), moreover the most infection (44.5%) was seen at a range of 21–30 yr. Conclusion: In the case of existing atypical issues to diagnose, it is needed to perform more precise microscopical examination beyond the current standard conditions. Sometimes molecular method is required to verify the exact agent of the disease. PMID:26811720

  10. The effectiveness of digital microscopy as a teaching tool in medical laboratory science curriculum.

    PubMed

    Castillo, Demetra

    2012-01-01

    A fundamental component to the practice of Medical Laboratory Science (MLS) is the microscope. While traditional microscopy (TM) is gold standard, the high cost of maintenance has led to an increased demand for alternative methods, such as digital microscopy (DM). Slides embedded with blood specimens are converted into a digital form that can be run with computer driven software. The aim of this study was to investigate the effectiveness of digital microscopy as a teaching tool in the field of Medical Laboratory Science. Participants reviewed known study slides using both traditional and digital microscopy methods and were assessed using both methods. Participants were randomly divided into two groups. Group 1 performed TM as the primary method and DM as the alternate. Group 2 performed DM as the primary and TM as the alternate. Participants performed differentials with their primary method, were assessed with both methods, and then performed differentials with their alternate method. A detailed assessment rubric was created to determine the accuracy of student responses through comparison of clinical laboratory and instructor results. Student scores were reflected as a percentage correct from these methods. This assessment was done over two different classes. When comparing results between methods for each, independent of the primary method used, results were not statistically different. However, when comparing methods between groups, Group 1 (n = 11) (TM = 73.79% +/- 9.19, DM = 81.43% +/- 8.30; paired t10 = 0.182, p < 0.001) showed a significant difference from Group 2 (n = 14) (TM = 85.64% +/- 5.30, DM = 85.91% +/- 7.62; paired t13 = 3.647, p = 0.860). In the subsequent class, results between both groups (n = 13, n = 16, respectively) did not show any significant difference between groups (Group 1 TM = 86.38% +/- 8.17, Group 1 DM = 88.69% +/- 3.86; paired t12 = 1.253, p = 0.234; Group 2 TM = 86.75% +/- 5.37, Group 2 DM = 86.25% +/- 7.01, paired t15 = 0.280, p

  11. Medical records for animals used in research, teaching, and testing: public statement from the American College of Laboratory Animal Medicine.

    PubMed

    Field, Karl; Bailey, Michele; Foresman, Larry L; Harris, Robert L; Motzel, Sherri L; Rockar, Richard A; Ruble, Gaye; Suckow, Mark A

    2007-01-01

    Medical records are considered to be a key element of a program of adequate veterinary care for animals used in research, teaching, and testing. However, prior to the release of the public statement on medical records by the American College of Laboratory Animal Medicine (ACLAM), the guidance that was available on the form and content of medical records used for the research setting was not consistent and, in some cases, was considered to be too rigid. To address this concern, ACLAM convened an ad hoc Medical Records Committee and charged the Committee with the task of developing a medical record guideline that was based on both professional judgment and performance standards. The Committee provided ACLAM with a guidance document titled Public Statements: Medical Records for Animals Used in Research, Teaching, and Testing, which was approved by ACLAM in late 2004. The ACLAM public statement on medical records provides guidance on the definition and content of medical records, and clearly identifies the Attending Veterinarian as the individual who is charged with authority and responsibility for oversight of the institution's medical records program. The document offers latitude to institutions in the precise form and process used for medical records but identifies typical information to be included in such records. As a result, the ACLAM public statement on medical records provides practical yet flexible guidelines to assure that documentation of animal health is performed in research, teaching, and testing situations.

  12. Changing resident test ordering behavior: a multilevel intervention to decrease laboratory utilization at an academic medical center.

    PubMed

    Vidyarthi, Arpana R; Hamill, Timothy; Green, Adrienne L; Rosenbluth, Glenn; Baron, Robert B

    2015-01-01

    Hospital laboratory test volume is increasing, and overutilization contributes to errors and costs. Efforts to reduce laboratory utilization have targeted aspects of ordering behavior, but few have utilized a multilevel collaborative approach. The study team partnered with residents to reduce unnecessary laboratory tests and associated costs through multilevel interventions across the academic medical center. The study team selected laboratory tests for intervention based on cost, volume, and ordering frequency (complete blood count [CBC] and CBC with differential, common electrolytes, blood enzymes, and liver function tests). Interventions were designed collaboratively with residents and targeted components of ordering behavior, including system changes, teaching, social marketing, academic detailing, financial incentives, and audit/feedback. Laboratory ordering was reduced by 8% cumulatively over 3 years, saving $2 019 000. By involving residents at every stage of the intervention and targeting multiple levels simultaneously, laboratory utilization was reduced and cost savings were sustained over 3 years.

  13. How compliant are technicians with universal safety measures in medical laboratories in Croatia? – A pilot study

    PubMed Central

    Dukic, Kristina; Zoric, Matea; Pozaic, Petra; Starcic, Jelena; Culjak, Marija; Saracevic, Andrea; Miler, Marijana

    2015-01-01

    Introduction This pilot study aimed to investigate the use of personal protective equipment (PPE) and compliance to the code of conduct (rules defined in institutional, governmental and professional guidelines) among laboratory technicians in Croatian medical laboratories. In addition, we explored the differences in compliance between participants of different age groups, laboratory ownership and accreditation status. Materials and methods An anonymous and voluntary survey with 15 questions was conducted among Croatian medical laboratory technicians (N = 217). The questions were divided into two groups: demographic characteristics and the use of PPE. The questions of the second part were graded according to the Likert scale (1-4) and an overall score, shown as median and range (min-max), was calculated for each participant. Differences between the overall scores were tested for each group of participants. Results The majority of participants always wear protective clothes at work, 38.7% of them always wear gloves in daily routine, more than 30.0% consume food and almost half of them drink beverages at workplace. A significantly lower overall score was found for participants working in public compared to private laboratories (36 (16-40) vs. 40 (31-40), P < 0.001). There were no statistically significant differences in overall scores for participants of different age groups (P = 0.456) and laboratory accreditation status (P = 0.081). Conclusion A considerable percentage of laboratory technicians in Croatian medical laboratories do not comply with safety measures. Lack of compliance is observed in all personnel regardless laboratory accreditation and participants’ age. However, those working in private laboratories adhere more to the code of conduct. PMID:26526817

  14. Practical solution for control of the pre-analytical phase in decentralized clinical laboratories for meeting the requirements of the medical laboratory accreditation standard DIN EN ISO 15189.

    PubMed

    Vacata, Vladimir; Jahns-Streubel, Gerlinde; Baldus, Mirjana; Wood, William Graham

    2007-01-01

    This report was written in response to the article by Wood published recently in this journal. It describes a practical solution to the problems of controlling the pre-analytical phase in the clinical diagnostic laboratory. As an indicator of quality in the pre-analytical phase of sample processing, a target analyte was chosen which is sensitive to delay in centrifugation and/or analysis. The results of analyses of the samples sent by satellite medical practitioners were compared with those from an on-site hospital laboratory with a controllable optimized pre-analytical phase. The aim of the comparison was: (a) to identify those medical practices whose mean/median sample values significantly deviate from those of the control situation in the hospital laboratory due to the possible problems in the pre-analytical phase; (b) to aid these laboratories in the process of rectifying these problems. A Microsoft Excel-based Pre-Analytical Survey tool (PAS tool) has been developed which addresses the above mentioned problems. It has been tested on serum potassium which is known to be sensitive to delay and/or irregularities in sample treatment. The PAS tool has been shown to be one possibility for improving the quality of the analyses by identifying the sources of problems within the pre-analytical phase, thus allowing them to be rectified. Additionally, the PAS tool has an educational value and can also be adopted for use in other decentralized laboratories.

  15. Clinical trials of boron neutron capture therapy [in humans] [at Beth Israel Deaconess Medical Center][at Brookhaven National Laboratory

    SciTech Connect

    Wallace, Christine

    2001-05-29

    Assessment of research records of Boron Neutron Capture Therapy was conducted at Brookhaven National Laboratory and Beth Israel Deaconess Medical Center using the Code of Federal Regulations, FDA Regulations and Good Clinical Practice Guidelines. Clinical data were collected from subjects' research charts, and differences in conduct of studies at both centers were examined. Records maintained at Brookhaven National Laboratory were not in compliance with regulatory standards. Beth Israel's records followed federal regulations. Deficiencies discovered at both sites are discussed in the reports.

  16. Proceedings of the Non-Linear Aero Prediction Requirements Workshop

    NASA Technical Reports Server (NTRS)

    Logan, Michael J. (Editor)

    1994-01-01

    The purpose of the Non-Linear Aero Prediction Requirements Workshop, held at NASA Langley Research Center on 8-9 Dec. 1993, was to identify and articulate requirements for non-linear aero prediction capabilities during conceptual/preliminary design. The attendees included engineers from industry, government, and academia in a variety of aerospace disciplines, such as advanced design, aerodynamic performance analysis, aero methods development, flight controls, and experimental and theoretical aerodynamics. Presentations by industry and government organizations were followed by panel discussions. This report contains copies of the presentations and the results of the panel discussions.

  17. Current practice in laboratory diagnostics of autoimmune diseases in Croatia. 
Survey of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine

    PubMed Central

    Kuna, Andrea Tešija; Đerek, Lovorka; Kozmar, Ana; Drvar, Vedrana

    2016-01-01

    Introduction With the trend of increasing incidence of autoimmune diseases, laboratories are faced with exponential growth of the requests for tests relating the diagnosis of these diseases. Unfortunately, the lack of laboratory personnel experienced in this specific discipline of laboratory diagnostic, as well as an unawareness of a method limitation often results in confusion for clinicians. The aim was to gain insight into number and type of Croatian laboratories that perform humoral diagnostics with the final goal to improve and harmonize laboratory diagnostics of autoimmune diseases in Croatia. Materials and methods In order to get insight into current laboratory practice two questionnaires, consisting of 42 questions in total, were created. Surveys were conducted using SurveyMonkey application and were sent to 88 medical biochemistry laboratories in Croatia for the first survey. Out of 33 laboratories that declared to perform diagnostic from the scope, 19 were selected for the second survey based on the tests they pleaded to perform. The survey comprised questions regarding autoantibody hallmarks of systemic autoimmune diseases while regarding organ-specific autoimmune diseases was limited to diseases of liver, gastrointestinal and nervous system. Results Response rate was high with 80 / 88 (91%) laboratories which answered the first questionnaire, and 19 / 19 (1.0) for the second questionnaire. Obtained results of surveys indicate high heterogeneity in the performance of autoantibody testing among laboratories in Croatia. Conclusions Results indicate the need of creating recommendations and algorithms in order to harmonize the approach to laboratory diagnostics of autoimmune diseases in Croatia. PMID:27812306

  18. Aero-Assisted Pre-Stage for Ballistic and Aero-Assisted Launch Vehicles

    NASA Technical Reports Server (NTRS)

    Ustinov, Eugene A.

    2012-01-01

    A concept of an aero-assisted pre-stage is proposed, which enables launch of both ballistic and aero-assisted launch vehicles from conventional runways. The pre-stage can be implemented as a delta-wing with a suitable undercarriage, which is mated with the launch vehicle, so that their flight directions are coaligned. The ample wing area of the pre-stage combined with the thrust of the launch vehicle ensure prompt roll-out and take-off of the stack at airspeeds typical for a conventional jet airliner. The launch vehicle is separated from the pre-stage as soon as safe altitude is achieved, and the desired ascent trajectory is reached. Nominally, the pre-stage is non-powered. As an option, to save the propellant of the launch vehicle, the pre-stage may have its own short-burn propulsion system, whereas the propulsion system of the launch vehicle is activated at the separation point. A general non-dimensional analysis of performance of the pre-stage from roll-out to separation is carried out and applications to existing ballistic launch vehicle and hypothetical aero-assisted vehicles (spaceplanes) are considered.

  19. The impact of gross anatomy laboratory on first year medical students' interest in a surgical career.

    PubMed

    Pulcrano, Marisa E; Malekzadeh, Sonya; Kumar, Anagha

    2016-09-01

    This study sought to determine the impact of gross anatomy laboratory (GA) on first year medical students' (M1) interest in a surgical career. Secondary objectives included identifying other influences in M1s' career decision making. This prospective study included surveys before and after GA. All M1s enrolled in GA were invited to participate. Sixty students completed both the pre- and post-test surveys. A 5-point Likert-type scale surveyed participants' interests, specific personality traits, experience during the course of GA, and likelihood of pursuing a surgical career. Statistical analysis included Wilcoxon Signed Rank Test and (Polychotomous) Ordinal Logistic Regression Model. Students' desire to work with their hands increased (50 vs. 33.3%) and enjoyment working with instruments and tools similarly increased (50 vs. 41.7%). Likelihood of pursuing a surgical career after gross anatomy increased in 31.7% of students, decreased in 16.7%, and was unchanged in 51.7%. Over 75% of students with a prior interest in surgery and 21% of those who previously felt neutral agreed that they were likely to pursue a career in surgery at the conclusion of the laboratory. Students with a surgeon family member were 0.1976 times as likely to exhibit a positive change in interest (P values 0.024). Gross anatomy may influence up to a third of the class to consider a surgical career, especially those with a prior interest in surgery and those previously feeling ambivalent. Students with a surgeon family member became less likely to enter a surgical career after gross anatomy. Clin. Anat. 29:691-695, 2016. © 2016 Wiley Periodicals, Inc.

  20. Musical preferences and learning outcome of medical students in cadaver dissection laboratory: A Nigerian survey.

    PubMed

    Anyanwu, G E; Nto, J N; Agu, A U; Ekezie, J; Esom, E A

    2016-11-01

    Background music has been reported to enhance learning in the cadaver dissection laboratory. This study was designed to determine the impact of various forms of musical genre and some of their characteristics on students' learning outcome in the dissection laboratory. Some selected musical genre in vocal and non-vocal forms and at different tempi and volume were played as background music (BM) to 253 Medical and Dental students during various sessions of cadaver dissection. Psychological Stress assessment was done using Psychological stress measure-9. Participants love for music, preferred musical genre and other musical characteristics were assessed. The impact of the various musical genre and their characteristics on learning was done via written examination on the region dissected during each musical session. A positive relationship was noted between students' preference for musical genre during leisure with their preference for BM during private study time (P<0.01). Statistically significant differences (P<0.01) were established in the impacts of the selected musical genre on some selected learning factors. Country and Classical music gave the highest positive impact on the various learning factors in CDL followed by R&B. No significant difference was noted between the cognitive values of vocal and non-vocal music. Classical music most effectively reduced the stress induced by dissection in the CDL while Reggae and High life musical genre created a more stressful environment than regular background noise (P<0.01). Moderate volume level and Tempo were most preferred during both cadaver dissection activity and leisure hours. This study shows statistically significant differences in the cognitive values of some of the studied musical genre and their various characteristics. The inability to isolate the particular musical genre with these desired properties could account for the controversies in the reports of the role of music in academic environment.

  1. Digital management and regulatory submission of medical images from clinical trials: role and benefits of the core laboratory

    NASA Astrophysics Data System (ADS)

    Robbins, William L.; Conklin, James J.

    1995-10-01

    Medical images (angiography, CT, MRI, nuclear medicine, ultrasound, x ray) play an increasingly important role in the clinical development and regulatory review process for pharmaceuticals and medical devices. Since medical images are increasingly acquired and archived digitally, or are readily digitized from film, they can be visualized, processed and analyzed in a variety of ways using digital image processing and display technology. Moreover, with image-based data management and data visualization tools, medical images can be electronically organized and submitted to the U.S. Food and Drug Administration (FDA) for review. The collection, processing, analysis, archival, and submission of medical images in a digital format versus an analog (film-based) format presents both challenges and opportunities for the clinical and regulatory information management specialist. The medical imaging 'core laboratory' is an important resource for clinical trials and regulatory submissions involving medical imaging data. Use of digital imaging technology within a core laboratory can increase efficiency and decrease overall costs in the image data management and regulatory review process.

  2. Medical Laboratory Technician--Hematology, Serology, Blood Banking & Immunohematology, 10-4. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This course, the third of three courses in the medical laboratory technician field adapted from military curriculum materials for use in vocational and technical education, was designed as a refresher course for student self-study and evaluation. It is suitable for use by advanced students or beginning students participating in a supervised…

  3. The medical heritage concept: a model for assuring comparable laboratory results in long-term longitudinal studies.

    PubMed

    Copeland, B E; Pesce, A J

    1992-01-01

    The success of a three or four decade health monitoring program depends upon the constancy and stability of the laboratory measurement data. This paper describes a prospective model which has been implemented as part of a 30-year health care program developed for the benefit of a particular group of residents who have lived for more than two years within five miles of an industrial plant which processed uranium metal and contaminated the surrounding area. Effective long-term laboratory monitoring (20 to 40 years) requires (1) a stable analytical base to establish comparability of all data collected, (2) innovative computer based record keeping, and (3) two selected reference populations which reflect method bias and widespread population change bias. To meet this need for comparability, the long-term Medical Heritage comparability concept was developed. This is an approach to the determination, storage, and retrieval of the laboratory data obtained on each specific participant in such a manner that all of that participant's data are internally comparable and continually traceable to definitive and/or reference methods developed by the National Institute for Standards and Technology and the Centers for Disease Control and the National Committee for Clinical Laboratory Standards. Systematic long-term documentation differentiates the Medical Heritage 30 to 40 year concept from the current short-term two- to three-year data continuity systems. As a model for long-term medical monitoring, the Medical Heritage comparability concept gives validity to individual patient care monitoring decisions.

  4. Anatomy and Humanity: Examining the Effects of a Short Documentary Film and First Anatomy Laboratory Experience on Medical Students

    ERIC Educational Resources Information Center

    Dosani, Farah; Neuberger, Lindsay

    2016-01-01

    Medical students begin their education inside a laboratory dissecting cadavers to learn human gross anatomy. Many schools use the course experience as a way to instill empathy and some have begun integrating video and recorded interviews with body donors to humanize the experience, but their impact has yet to be measured. This study examines the…

  5. Medical Laboratory Technician--Chemical Chemistry & Urinalysis, 10-2. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This publication, the last of three course materials in the medical laboratory technician field adapted from the Military Curriculum Materials for Use in Technical and Vocational Education series, was designed as a refresher course for student self-study and evaluation. It can be used by advanced students or beginning students participating in a…

  6. 76 FR 52042 - Auriga Laboratories, Inc., Curon Medical, Inc., Goldstate Corp., OneWorld Systems, Inc., and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Auriga Laboratories, Inc., Curon Medical, Inc., Goldstate Corp., OneWorld Systems, Inc., and... securities of OneWorld Systems, Inc. because it has not filed any periodic reports since the period...

  7. Conference scene: Summary of the 6th Conference of the Romanian Association of Medical Laboratories with international participation.

    PubMed

    Carasevici, Eugen

    2011-10-01

    The Romanian Association of Medical Laboratories (RAML) conferences have acquired a reputation for standing out as the most prominent and efficient meetings in the national community of laboratory medicine, being a landmark of the development in this field in Romania and an active affiliation to international forums. This year, the conference setting was Piatra Neamt, in the northeast part of Romania, which produced a friendly and stimulating professional environment. As in previous years, leading experts in the fields of laboratory medicine attended the event. This year, we enjoyed the opportunity to have such distinguished guests as the members of the executive board of International Federation of Clinical Chemistry and Laboratory Medicine (IFCC); Graham Beastall, IFCC President; Päivi Hannele Laitinen, IFCC secretary; and Grazyna Sypniewska, IFCC Communication and Publication Division, and editor of the electronic journal of the IFCC. As usual, the conference program included all aspects of clinical laboratory activity, with a special focus on technology development, instrumentation and laboratory management. Fully aware of the fact that the complexity and depth of laboratory practice have undergone an impressive and rapid evolution, the specific goals of the event were to increase knowledge in the fundamentals of new molecular investigation, areas which show the tendency to become routine in our daily activity. In addition, laboratory management and the place of medical laboratories in the process of translational medicine were subjects of focus. The 6th Conference of the Romanian Association of Medical Laboratories was held from Wednesday 1st to Saturday 4th of June 2011. A total of 273 participants from all local branches of the Association attended. The scientific program included seven plenary sessions where 22 lectures and 18 short communications were delivered, and three poster sessions with 44 poster presentations. Session topics covered issues of

  8. Aeronautical Mobile Airport Communications System (AeroMACS)

    NASA Technical Reports Server (NTRS)

    Budinger, James M.; Hall, Edward

    2011-01-01

    To help increase the capacity and efficiency of the nation s airports, a secure wideband wireless communications system is proposed for use on the airport surface. This paper provides an overview of the research and development process for the Aeronautical Mobile Airport Communications System (AeroMACS). AeroMACS is based on a specific commercial profile of the Institute of Electrical and Electronics Engineers (IEEE) 802.16 standard known as Wireless Worldwide Interoperability for Microwave Access or WiMAX (WiMax Forum). The paper includes background on the need for global interoperability in air/ground data communications, describes potential AeroMACS applications, addresses allocated frequency spectrum constraints, summarizes the international standardization process, and provides findings and recommendations from the world s first AeroMACS prototype implemented in Cleveland, Ohio, USA.

  9. MEMS and mil/aero: technology push and market pull

    NASA Astrophysics Data System (ADS)

    Clifford, Thomas H.

    2001-04-01

    MEMS offers attractive solutions to high-density fluidics, inertial, optical, switching and other demanding military/aerospace (mil/aero) challenges. However, full acceptance must confront the realities of production-scale producibility, verifiability, testability, survivability, as well as long-term reliability. Data on these `..ilities' are crucial, and are central in funding and deployment decisions. Similarly, mil/aero users must highlight specific missions, environmental exposures, and procurement issues, as well as the quirks of its designers. These issues are particularly challenging in MEMS, because of the laws of physics and business economics, as well as the risks of deploying leading-edge technology into no-fail applications. This paper highlights mil/aero requirements, and suggests reliability/qualification protocols, to guide development effort and to reassure mil/aero users that MEMS labs are mindful of the necessary realities.

  10. Capillary blood sampling: national recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine.

    PubMed

    Krleza, Jasna Lenicek; Dorotic, Adrijana; Grzunov, Ana; Maradin, Miljenka

    2015-01-01

    Capillary blood sampling is a medical procedure aimed at assisting in patient diagnosis, management and treatment, and is increasingly used worldwide, in part because of the increasing availability of point-of-care testing. It is also frequently used to obtain small blood volumes for laboratory testing because it minimizes pain. The capillary blood sampling procedure can influence the quality of the sample as well as the accuracy of test results, highlighting the need for immediate, widespread standardization. A recent nationwide survey of policies and practices related to capillary blood sampling in medical laboratories in Croatia has shown that capillary sampling procedures are not standardized and that only a small proportion of Croatian laboratories comply with guidelines from the Clinical Laboratory Standards Institute (CLSI) or the World Health Organization (WHO). The aim of this document is to provide recommendations for capillary blood sampling. This document has been produced by the Working Group for Capillary Blood Sampling within the Croatian Society of Medical Biochemistry and Laboratory Medicine. Our recommendations are based on existing available standards and recommendations (WHO Best Practices in Phlebotomy, CLSI GP42-A6 and CLSI C46-A2), which have been modified based on local logistical, cultural, legal and regulatory requirements. We hope that these recommendations will be a useful contribution to the standardization of capillary blood sampling in Croatia.

  11. [Internal audit in medical laboratory: what means of control for an effective audit process?].

    PubMed

    Garcia-Hejl, Carine; Chianéa, Denis; Dedome, Emmanuel; Sanmartin, Nancy; Bugier, Sarah; Linard, Cyril; Foissaud, Vincent; Vest, Philippe

    2013-01-01

    To prepare the French Accreditation Committee (COFRAC) visit for initial certification of our medical laboratory, our direction evaluated its quality management system (QMS) and all its technical activities. This evaluation was performed owing an internal audit. This audit was outsourced. Auditors had an expertise in audit, a whole knowledge of biological standards and were independent. Several nonconformities were identified at that time, including a lack of control of several steps of the internal audit process. Hence, necessary corrective actions were taken in order to meet the requirements of standards, in particular, the formalization of all stages, from the audit program, to the implementation, review and follow-up of the corrective actions taken, and also the implementation of the resources needed to carry out audits in a pre-established timing. To ensure an optimum control of each step, the main concepts of risk management were applied: process approach, root cause analysis, effects and criticality analysis (FMECA). After a critical analysis of our practices, this methodology allowed us to define our "internal audit" process, then to formalize it and to follow it up, with a whole documentary system.

  12. Ethical and methodological standards for laboratory and medical biological rhythm research.

    PubMed

    Portaluppi, Francesco; Touitou, Yvan; Smolensky, Michael H

    2008-11-01

    The main objectives of this article are to update the ethical standards for the conduct of human and animal biological rhythm research and recommend essential elements for quality chronobiological research information, which should be especially useful for new investigators of the rhythms of life. A secondary objective is to provide for those with an interest in the results of chronobiology investigations, but who might be unfamiliar with the field, an introduction to the basic methods and standards of biological rhythm research and time series data analysis. The journal and its editors endorse compliance of all investigators to the principles of the Declaration of Helsinki of the World Medical Association, which relate to the conduct of ethical research on human beings, and the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council, which relate to the conduct of ethical research on laboratory and other animals. The editors and the readers of the journal expect the authors of submitted manuscripts to have adhered to the ethical standards dictated by local, national, and international laws and regulations in the conduct of investigations and to be unbiased and accurate in reporting never-before-published research findings. Authors of scientific papers are required to disclose all potential conflicts of interest, particularly when the research is funded in part or in full by the medical and pharmaceutical industry, when the authors are stock-holders of the company that manufactures or markets the products under study, or when the authors are a recent or current paid consultant to the involved company. It is the responsibility of the authors of submitted manuscripts to clearly present sufficient detail about the synchronizer schedule of the studied subjects (i.e., the sleep-wake schedule, ambient light-dark cycle, intensity and spectrum of ambient light exposure, seasons when the research was

  13. Aero-Assisted Spacecraft Missions Using Hypersonic Waverider Aeroshells

    NASA Astrophysics Data System (ADS)

    Knittel, Jeremy

    This work examines the use of high-lift, low drag vehicles which perform orbital transfers within a planet's atmosphere to reduce propulsive requirements. For the foreseeable future, spacecraft mission design will include the objective of limiting the mass of fuel required. One means of accomplishing this is using aerodynamics as a supplemental force, with what is termed an aero-assist maneuver. Further, the use of a lifting body enables a mission designer to explore candidate trajectory types wholly unavailable to non-lifting analogs. Examples include missions to outer planets by way of an aero-gravity assist, aero-assisted plane change, aero-capture, and steady atmospheric periapsis probing missions. Engineering level models are created in order to simulate both atmospheric and extra-atmospheric space flight. Each mission is parameterized using discrete variables which control multiple areas of design. This work combines the areas of hypersonic aerodynamics, re-entry aerothermodynamics, spacecraft orbital mechanics, and vehicle shape optimization. In particular, emphasis is given to the parametric design of vehicles known as "waveriders" which are inversely designed from known shock flowfields. An entirely novel means of generating a class of waveriders known as "starbodies" is presented. A complete analysis is performed of asymmetric starbody forms and compared to a better understood parameterization, "osculating cone" waveriders. This analysis includes characterization of stability behavior, a critical discipline within hypersonic flight. It is shown that asymmetric starbodies have significant stability improvement with only a 10% reduction in the lift-to-drag ratio. By combining the optimization of both the shape of the vehicle and the trajectory it flies, much is learned about the benefit that can be expected from lifting aero-assist missions. While previous studies have conceptually proven the viability, this work provides thorough quantification of the

  14. Current and Projected Modes of Delivery of Veterinary Medical Services to Animal Agriculture: Diagnostic Laboratory Services.

    ERIC Educational Resources Information Center

    Seaton, Vaughn A.

    1980-01-01

    The veterinary diagnostic laboratory's prime role has been diagnosis and/or laboratory findings to assist a diagnosis. Interpretation and evaluation and more involvement with decision-making in monitoring groups of animals and their health status are seen as future roles for diagnostic laboratories. (MLW)

  15. Molecular pathology curriculum for medical laboratory scientists: A report of the association for molecular pathology training and education committee.

    PubMed

    Taylor, Sara; Bennett, Katie M; Deignan, Joshua L; Hendrix, Ericka C; Orton, Susan M; Verma, Shalini; Schutzbank, Ted E

    2014-05-01

    Molecular diagnostics is a rapidly growing specialty in the clinical laboratory assessment of pathology. Educational programs in medical laboratory science and specialized programs in molecular diagnostics must address the training of clinical scientists in molecular diagnostics, but the educational curriculum for this field is not well defined. Moreover, our understanding of underlying genetic contributions to specific diseases and the technologies used in molecular diagnostics laboratories change rapidly, challenging providers of training programs in molecular diagnostics to keep their curriculum current and relevant. In this article, we provide curriculum recommendations to molecular diagnostics training providers at both the baccalaureate and master's level of education. We base our recommendations on several factors. First, we considered National Accrediting Agency for Clinical Laboratory Sciences guidelines for accreditation of molecular diagnostics programs, because educational programs in clinical laboratory science should obtain its accreditation. Second, the guidelines of several of the best known certifying agencies for clinical laboratory scientists were incorporated into our recommendations. Finally, we relied on feedback from current employers of molecular diagnostics scientists, regarding the skills and knowledge that they believe are essential for clinical scientists who will be performing molecular testing in their laboratories. We have compiled these data into recommendations for a molecular diagnostics curriculum at both the baccalaureate and master's level of education.

  16. A Review of Bachelor’s Degree Medical Laboratory Scientist Education and Entry Level Practice in the United States

    PubMed Central

    2013-01-01

    The baccalaureate degree is generally the degree that provides the laboratory professional with the greatest level of general scientific background, training, job flexibility, and advancement opportunities. It is widely considered the requirement for entry-level work in the field of medical laboratory science, especially for those that covet work in management or specialty areas. This paper focuses on the educational models and levels of practice for MLS professionals including the entry level competencies of new professionals at the baccalaureate level. The accreditation of MLS programs and professional certification serve as important quality management systems to ensure program quality and professional competency prior to the start of entry level work. PMID:27683433

  17. A Review of Bachelor's Degree Medical Laboratory Scientist Education and Entry Level Practice in the United States.

    PubMed

    Scanlan, Perry M

    2013-04-01

    The baccalaureate degree is generally the degree that provides the laboratory professional with the greatest level of general scientific background, training, job flexibility, and advancement opportunities. It is widely considered the requirement for entry-level work in the field of medical laboratory science, especially for those that covet work in management or specialty areas. This paper focuses on the educational models and levels of practice for MLS professionals including the entry level competencies of new professionals at the baccalaureate level. The accreditation of MLS programs and professional certification serve as important quality management systems to ensure program quality and professional competency prior to the start of entry level work.

  18. Modular Aero-Propulsion System Simulation

    NASA Technical Reports Server (NTRS)

    Parker, Khary I.; Guo, Ten-Huei

    2006-01-01

    The Modular Aero-Propulsion System Simulation (MAPSS) is a graphical simulation environment designed for the development of advanced control algorithms and rapid testing of these algorithms on a generic computational model of a turbofan engine and its control system. MAPSS is a nonlinear, non-real-time simulation comprising a Component Level Model (CLM) module and a Controller-and-Actuator Dynamics (CAD) module. The CLM module simulates the dynamics of engine components at a sampling rate of 2,500 Hz. The controller submodule of the CAD module simulates a digital controller, which has a typical update rate of 50 Hz. The sampling rate for the actuators in the CAD module is the same as that of the CLM. MAPSS provides a graphical user interface that affords easy access to engine-operation, engine-health, and control parameters; is used to enter such input model parameters as power lever angle (PLA), Mach number, and altitude; and can be used to change controller and engine parameters. Output variables are selectable by the user. Output data as well as any changes to constants and other parameters can be saved and reloaded into the GUI later.

  19. Aero-Thermo-Dynamic Mass Analysis

    PubMed Central

    Shiba, Kota; Yoshikawa, Genki

    2016-01-01

    Each gas molecule has its own molecular weight, while such a microscopic characteristic is generally inaccessible, and thus, it is measured indirectly through e.g. ionization in conventional mass analysis. Here, we present a novel approach to the direct measurement of molecular weight through a nanoarchitectonic combination of aerodynamics, thermodynamics, and mechanics, transducing microscopic events into macroscopic phenomena. It is confirmed that this approach can provide molecular weight of virtually any gas or vaporizable liquid sample in real-time without ionization. Demonstrations through analytical calculations, numerical simulations, and experiments verify the validity and versatility of the novel mass analysis realized by a simple setup with a flexible object (e.g. with a bare cantilever and even with a business card) placed in a laminar jet. Owing to its unique and simple working principle, this aero-thermo-dynamic mass analysis (AMA) can be integrated into various analytical devices, production lines, and consumer mobile platforms, opening new chapters in aerodynamics, thermodynamics, mechanics, and mass analysis. PMID:27412335

  20. Aero-Thermo-Dynamic Mass Analysis.

    PubMed

    Shiba, Kota; Yoshikawa, Genki

    2016-07-14

    Each gas molecule has its own molecular weight, while such a microscopic characteristic is generally inaccessible, and thus, it is measured indirectly through e.g. ionization in conventional mass analysis. Here, we present a novel approach to the direct measurement of molecular weight through a nanoarchitectonic combination of aerodynamics, thermodynamics, and mechanics, transducing microscopic events into macroscopic phenomena. It is confirmed that this approach can provide molecular weight of virtually any gas or vaporizable liquid sample in real-time without ionization. Demonstrations through analytical calculations, numerical simulations, and experiments verify the validity and versatility of the novel mass analysis realized by a simple setup with a flexible object (e.g. with a bare cantilever and even with a business card) placed in a laminar jet. Owing to its unique and simple working principle, this aero-thermo-dynamic mass analysis (AMA) can be integrated into various analytical devices, production lines, and consumer mobile platforms, opening new chapters in aerodynamics, thermodynamics, mechanics, and mass analysis.

  1. Aero-Thermo-Dynamic Mass Analysis

    NASA Astrophysics Data System (ADS)

    Shiba, Kota; Yoshikawa, Genki

    2016-07-01

    Each gas molecule has its own molecular weight, while such a microscopic characteristic is generally inaccessible, and thus, it is measured indirectly through e.g. ionization in conventional mass analysis. Here, we present a novel approach to the direct measurement of molecular weight through a nanoarchitectonic combination of aerodynamics, thermodynamics, and mechanics, transducing microscopic events into macroscopic phenomena. It is confirmed that this approach can provide molecular weight of virtually any gas or vaporizable liquid sample in real-time without ionization. Demonstrations through analytical calculations, numerical simulations, and experiments verify the validity and versatility of the novel mass analysis realized by a simple setup with a flexible object (e.g. with a bare cantilever and even with a business card) placed in a laminar jet. Owing to its unique and simple working principle, this aero-thermo-dynamic mass analysis (AMA) can be integrated into various analytical devices, production lines, and consumer mobile platforms, opening new chapters in aerodynamics, thermodynamics, mechanics, and mass analysis.

  2. A review of data on laboratory colonies of bed bugs (Cimicidae), an insect of emerging medical relevance

    PubMed Central

    Cannet, Arnaud; Akhoundi, Mohammad; Berenger, Jean-Michel; Michel, Gregory; Marty, Pierre; Delaunay, Pascal

    2015-01-01

    Cimicidae are hematophagous Heteroptera, feeding on human blood, that have been the subject of significant medical investigation. In particular, they have been colonized under laboratory conditions to study their medical relevance. Laboratory colonization of these bugs is a multifactorial phenomenon. Our goal was to conduct a comparative literature review to classify the published data, demonstrating preferred bed bug colony conditions. We show that physical factors including temperature, relative humidity and photoperiod, and physiological factors such as type and frequency of blood meals play important roles in laboratory colonies. Any change in these factors produces changes in life-cycle duration. Temperature and blood meal are the most important factors, with a marked impact on the life-cycle of laboratory populations, depending on the species. A wide range of temperatures (15–34 °C) and relative humidity (46–75%) with an average of 25 °C and 59% were found for these colonies. Two widely used blood sources for the colonies were rabbits and humans. PMID:26091944

  3. A review of data on laboratory colonies of bed bugs (Cimicidae), an insect of emerging medical relevance.

    PubMed

    Cannet, Arnaud; Akhoundi, Mohammad; Berenger, Jean-Michel; Michel, Gregory; Marty, Pierre; Delaunay, Pascal

    2015-01-01

    Cimicidae are hematophagous Heteroptera, feeding on human blood, that have been the subject of significant medical investigation. In particular, they have been colonized under laboratory conditions to study their medical relevance. Laboratory colonization of these bugs is a multifactorial phenomenon. Our goal was to conduct a comparative literature review to classify the published data, demonstrating preferred bed bug colony conditions. We show that physical factors including temperature, relative humidity and photoperiod, and physiological factors such as type and frequency of blood meals play important roles in laboratory colonies. Any change in these factors produces changes in life-cycle duration. Temperature and blood meal are the most important factors, with a marked impact on the life-cycle of laboratory populations, depending on the species. A wide range of temperatures (15-34 °C) and relative humidity (46-75%) with an average of 25 °C and 59% were found for these colonies. Two widely used blood sources for the colonies were rabbits and humans.

  4. A New Paradigm for Teaching Histology Laboratories in Canada's First Distributed Medical School

    ERIC Educational Resources Information Center

    Pinder, Karen E.; Ford, Jason C.; Ovalle, William K.

    2008-01-01

    To address the critical problem of inadequate physician supply in rural British Columbia, The University of British Columbia (UBC) launched an innovative, expanded and distributed medical program in 2004-2005. Medical students engage in a common curriculum at three geographically distinct sites across B.C.: in Vancouver, Prince George and…

  5. Anatomy and humanity: Examining the effects of a short documentary film and first anatomy laboratory experience on medical students.

    PubMed

    Dosani, Farah; Neuberger, Lindsay

    2016-01-01

    Medical students begin their education inside a laboratory dissecting cadavers to learn human gross anatomy. Many schools use the course experience as a way to instill empathy and some have begun integrating video and recorded interviews with body donors to humanize the experience, but their impact has yet to be measured. This study examines the effects of a brief documentary film and the initial cadaver encounter on student perceptions and attitudes towards the laboratory experience. A pre-test, exposure, post-test design was used with 77 first-year medical students at the University of Central Florida. A previously validated questionnaire was adapted to measure attitudes, emotions, initial reaction to cadaver, perception of the donor as a person, and impressions of the film. An online questionnaire was completed before the first day of laboratory, in which students watched the film Anatomy and Humanity and handled their respective cadavers (no dissection was performed). The post-test was administered immediately following the activities of the first laboratory day. Results indicate an increase in negative attitudes towards dissection, but a more positive initial reaction to the cadaver than originally anticipated. Students also experienced a decrease in emotions like sadness and guilt regarding anatomy laboratory and were less likely to view the cadaver as a once-living person. Findings suggest a higher comfort level, but also greater detachment toward the cadavers from day one despite the video intervention. These results provide novel insight that may aid other interventions aimed at promoting humanism in the anatomy laboratory experience.

  6. Quality control of the isolation rate of pathogens in medical microbiology laboratories.

    PubMed Central

    Tillett, H. E.; Crone, P. B.

    1976-01-01

    Two statistical analyses are suggested to compare the success rates in isolating and identifying pathogenic organisms from specimens achieved by different laboratories participating in a quality control scheme. An example is given in which the analyses are applied to 25 laboratories that received 30 simulated specimens. PMID:1069816

  7. Investigating clandestine drug laboratories: adverse medical effects in law enforcement personnel.

    PubMed

    Burgess, J L; Barnhart, S; Checkoway, H

    1996-10-01

    A retrospective cohort study was conducted among an international group of 46 law enforcement chemists and 13 Washington State clandestine drug laboratory investigation team members with more than 2,800 combined investigations. Each participant completed a questionnaire concerning previous drug laboratory investigations and adverse health effects during response activities. Methamphetamine laboratories accounted for 81-97% of all responses. Total illness incident rates varied between 0.75-3.4% of responses. Most exposures were through inhalation, and many occurred in the years prior to use of personal protective equipment. Symptoms were primarily those of headache and respiratory, mucous membrane, and skin irritation. Most illness episodes occurred during the processing phase of laboratory responses, and none occurred during the entry phase. A majority of illness episodes occurred in laboratories with leak/spills, fire/explosion, or uncontrolled reactions. Responding to an active laboratory was associated with a 7 to 15-fold risk of becoming ill as compared with setup, in-transit, or former (equipment removed) laboratory responses. No other laboratories characteristics were consistently associated with a significantly elevated relative risk of adverse health effects.

  8. Laboratory testing of extravascular body fluids in Croatia: a survey of the Working group for extravascular body fluids of the Croatian Society of Medical Biochemistry and Laboratory Medicine

    PubMed Central

    Kopcinovic, Lara Milevoj; Vogrinc, Zeljka; Kocijan, Irena; Culej, Jelena; Aralica, Merica; Jokic, Anja; Antoncic, Dragana; Bozovic, Marija

    2016-01-01

    Introduction We hypothesized that extravascular body fluid (EBF) analysis in Croatia is not harmonized and aimed to investigate preanalytical, analytical and postanalytical procedures used in EBF analysis in order to identify key aspects that should be addressed in future harmonization attempts. Materials and methods An anonymous online survey created to explore laboratory testing of EBF was sent to secondary, tertiary and private health care Medical Biochemistry Laboratories (MBLs) in Croatia. Statements were designed to address preanalytical, analytical and postanalytical procedures of cerebrospinal, pleural, peritoneal (ascites), pericardial, seminal, synovial, amniotic fluid and sweat. Participants were asked to declare the strength of agreement with proposed statements using a Likert scale. Mean scores for corresponding separate statements divided according to health care setting were calculated and compared. Results The survey response rate was 0.64 (58 / 90). None of the participating private MBLs declared to analyse EBF. We report a mean score of 3.45 obtained for all statements evaluated. Deviations from desirable procedures were demonstrated in all EBF testing phases. Minor differences in procedures used for EBF analysis comparing secondary and tertiary health care MBLs were found. The lowest scores were obtained for statements regarding quality control procedures in EBF analysis, participation in proficiency testing programmes and provision of interpretative comments on EBF’s test reports. Conclusions Although good laboratory EBF practice is present in Croatia, procedures for EBF analysis should be further harmonized to improve the quality of EBF testing and patient safety. PMID:27812307

  9. Laboratory Graduate Fellowship Program, 1989. Appendix A. Forms

    DTIC Science & Technology

    1989-01-01

    institution listed. Transcripts should be LABORATORY LIST LABORATORY 1: LABORATORY 5: AERO PROPULSION LABORATORY ENGINEERING AND SERVICES CENTER Wright...Patterson AFB, (Dayton), Ohio Tyndall AFB, (Panama City), Florida Research Programs in Airbreathing Propulsion , Aerospace Power, Research in the...Sciences d. Hypersonic Flows relating to Rocket Propulsion and Interdisciplinary Space e. High Temperature Structural Behavior Technology for future ICBMs

  10. Aero-Structural Interaction, Analysis, and Shape Sensitivity

    NASA Technical Reports Server (NTRS)

    Newman, James C., III

    1999-01-01

    A multidisciplinary sensitivity analysis technique that has been shown to be independent of step-size selection is examined further. The accuracy of this step-size independent technique, which uses complex variables for determining sensitivity derivatives, has been previously established. The primary focus of this work is to validate the aero-structural analysis procedure currently being used. This validation consists of comparing computed and experimental data obtained for an Aeroelastic Research Wing (ARW-2). Since the aero-structural analysis procedure has the complex variable modifications already included into the software, sensitivity derivatives can automatically be computed. Other than for design purposes, sensitivity derivatives can be used for predicting the solution at nearby conditions. The use of sensitivity derivatives for predicting the aero-structural characteristics of this configuration is demonstrated.

  11. Medical laboratory science and nursing students’ perception of academic learning environment in a Philippine university using Dundee Ready Educational Environment Measure (DREEM)

    PubMed Central

    2016-01-01

    Purpose This study aimed to compare the perception of the academic learning environment between medical laboratory science students and nursing students at Saint Louis University, Baguio City, Philippines. Methods A cross-sectional survey research design was used to measure the perceptions of the participants. A total of 341 students from the Department of Medical Laboratory Science, School of Natural Sciences, and the School of Nursing answered the Dundee Ready Education Environment Measure (DREEM) instrument from April to May 2016. Responses were compared according to course of study, gender, and year level. Results The total mean DREEM scores of the medical laboratory science students and nursing students did not differ significantly when grouped according to course of study, gender, or year level. Medical laboratory science students had significantly lower mean scores in the sub-domains ‘perception of learning’ and ‘perception of teaching.’ Male medical laboratory science students had significantly lower mean scores in the sub-domain ‘perception of learning’ among second year students. Medical laboratory science students had significantly lower mean scores in the sub-domain ‘perception of learning.’ Nursing students identified 7 problem areas, most of which were related to their instructors. Conclusion Medical laboratory science and nursing students viewed their academic learning environment as ‘more positive than negative.’ However, the relationship of the nursing instructors to their students needs improvement. PMID:27649901

  12. Vehicle Health Management Communications Requirements for AeroMACS

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert J.; Clements, Donna J.; Apaza, Rafael D.

    2012-01-01

    As the development of standards for the aeronautical mobile airport communications system (AeroMACS) progresses, the process of identifying and quantifying appropriate uses for the system is progressing. In addition to defining important elements of AeroMACS standards, indentifying the systems uses impacts AeroMACS bandwidth requirements. Although an initial 59 MHz spectrum allocation for AeroMACS was established in 2007, the allocation may be inadequate; studies have indicated that 100 MHz or more of spectrum may be required to support airport surface communications. Hence additional spectrum allocations have been proposed. Vehicle health management (VHM) systems, which can produce large volumes of vehicle health data, were not considered in the original bandwidth requirements analyses, and are therefore of interest in supporting proposals for additional AeroMACS spectrum. VHM systems are an emerging development in air vehicle safety, and preliminary estimates of the amount of data that will be produced and transmitted off an aircraft, both in flight and on the ground, have been prepared based on estimates of data produced by on-board vehicle health sensors and initial concepts of data processing approaches. This allowed an initial estimate of VHM data transmission requirements for the airport surface. More recently, vehicle-level systems designed to process and analyze VHM data and draw conclusions on the current state of vehicle health have been undergoing testing and evaluation. These systems make use of vehicle system data that is mostly different from VHM data considered previously for airport surface transmission, and produce processed system outputs that will be also need to be archived, thus generating additional data load for AeroMACS. This paper provides an analysis of airport surface data transmission requirements resulting from the vehicle level reasoning systems, within the context of overall VHM data requirements.

  13. Teaching baroreflex physiology to medical students: a comparison of quiz-based and conventional teaching strategies in a laboratory exercise.

    PubMed

    Berg, Ronan M G; Plovsing, Ronni R; Damgaard, Morten

    2012-06-01

    Quiz-based and collaborative teaching strategies have previously been found to be efficient for the improving meaningful learning of physiology during lectures. These approaches have, however, not been investigated during laboratory exercises. In the present study, we compared the impact of solving quizzes individually and in groups with conventional teaching on the immediate learning during a laboratory exercise. We implemented two quizzes in a mandatory 4-h laboratory exercise on baroreflex physiology. A total of 155 second-year medical students were randomized to solve quizzes individually (intervention group I, n = 57), in groups of three to four students (intervention group II, n = 56), or not to perform any quizzes (control; intervention group III, n = 42). After the laboratory exercise, all students completed an individual test, which encompassed two recall questions, two intermediate questions, and two integrated questions. The integrated questions were of moderate and advanced difficulty, respectively. Finally, students completed an evaluation form. Intervention group I reached the highest total test scores and proved best at answering the integrated question of advanced difficulty. Moreover, there was an overall difference between groups for student evaluations of the quality of the teaching, which was highest for intervention group II. In conclusion, solving quizzes individually during a laboratory exercise may enhance learning, whereas solving quizzes in groups is associated with higher student satisfaction.

  14. Preanalytical errors in medical laboratories: a review of the available methodologies of data collection and analysis.

    PubMed

    West, Jamie; Atherton, Jennifer; Costelloe, Seán J; Pourmahram, Ghazaleh; Stretton, Adam; Cornes, Michael

    2017-01-01

    Preanalytical errors have previously been shown to contribute a significant proportion of errors in laboratory processes and contribute to a number of patient safety risks. Accreditation against ISO 15189:2012 requires that laboratory Quality Management Systems consider the impact of preanalytical processes in areas such as the identification and control of non-conformances, continual improvement, internal audit and quality indicators. Previous studies have shown that there is a wide variation in the definition, repertoire and collection methods for preanalytical quality indicators. The International Federation of Clinical Chemistry Working Group on Laboratory Errors and Patient Safety has defined a number of quality indicators for the preanalytical stage, and the adoption of harmonized definitions will support interlaboratory comparisons and continual improvement. There are a variety of data collection methods, including audit, manual recording processes, incident reporting mechanisms and laboratory information systems. Quality management processes such as benchmarking, statistical process control, Pareto analysis and failure mode and effect analysis can be used to review data and should be incorporated into clinical governance mechanisms. In this paper, The Association for Clinical Biochemistry and Laboratory Medicine PreAnalytical Specialist Interest Group review the various data collection methods available. Our recommendation is the use of the laboratory information management systems as a recording mechanism for preanalytical errors as this provides the easiest and most standardized mechanism of data capture.

  15. Vortex-Based Aero- and Hydrodynamic Estimation

    NASA Astrophysics Data System (ADS)

    Hemati, Maziar Sam

    Flow control strategies often require knowledge of unmeasurable quantities, thus presenting a need to reconstruct flow states from measurable ones. In this thesis, the modeling, simulation, and estimator design aspects of flow reconstruction are considered. First, a vortex-based aero- and hydrodynamic estimation paradigm is developed to design a wake sensing algorithm for aircraft formation flight missions. The method assimilates wing distributed pressure measurements with a vortex-based wake model to better predict the state of the flow. The study compares Kalman-type algorithms with particle filtering algorithms, demonstrating that the vortex nonlinearities require particle filters to yield adequate performance. Furthermore, the observability structure of the wake is shown to have a negative impact on filter performance regardless of the algorithm applied. It is demonstrated that relative motions can alleviate the filter divergence issues associated with this observability structure. In addition to estimator development, the dissertation addresses the need for an efficient unsteady multi-body aerodynamics testbed for estimator and controller validation studies. A pure vortex particle implementation of a vortex panel-particle method is developed to satisfy this need. The numerical method is demonstrated on the impulsive startup of a flat plate as well as the impulsive startup of a multi-wing formation. It is clear, from these validation studies, that the method is able to accommodate the unsteady wake effects that arise in formation flight missions. Lastly, successful vortex-based estimation is highly dependent on the reliability of the low-order vortex model used in representing the flow of interest. The present treatise establishes a systematic framework for vortex model improvement, grounded in optimal control theory and the calculus of variations. By minimizing model predicted errors with respect to empirical data, the shortcomings of the baseline vortex model

  16. Laboratory and flight tests of medical equipment for use in U.S. Army Medevac helicopters.

    PubMed

    Bruckart, J E; Licina, J R; Quattlebaum, M

    1993-03-01

    When used in an air medical setting, medical equipment designed for use in hospitals can fail from the stresses of in-flight use, or they interfere with critical rotor-wing aircraft systems. From January 1989 to June 1992, 34 medical devices, including monitor/defibrillators, infusion pumps, vital-signs monitors, ventilators and infant transport incubators, were tested under extreme conditions of temperature, humidity, altitude and vibration (MIL-STD 810D). Electromagnetic emissions and susceptibility were measured (MIL-STD 461C and 462), and human factors were evaluated. The devices were flight tested in a UH-60 MEDEVAC helicopter. Thirty-two percent of the medical devices failed at least one environmental test, and 91% of the devices failed to meet electromagnetic interference standards. Failures included excess conducted and radiated emissions and susceptibility to radiated emissions. Five (15%) of the devices were judged unsuitable for use in the UH-60 MEDEVAC helicopter. Testing is critical to discover the ability of a medical device to perform in the harsh rotor-wing MEDEVAC environment. Failure of a device or interference with aircraft systems can result in loss of a patient or aircrew.

  17. Policies and practices in haemostasis testing among laboratories in Croatia: a survey on behalf of a Working Group for Laboratory Coagulation of the Croatian Society of Medical Biochemistry and Laboratory Medicine

    PubMed Central

    Bronić, Ana; Herak, Desiree Coen; Margetić, Sandra; Milić, Marija

    2017-01-01

    Introduction The objective of this survey was to assess current policies and practice in haemostasis testing among both hospital and outpatient laboratories in Republic of Croatia. Materials and methods A questionnaire with seventy questions divided into nine sections was created in May 2015. Participants were asked about their practice related to test request form, sample collection, prothrombin time (PT) and activated partial thromboplastin time assays, other individual haemostasis assays, point-of-care testing (POCT), reporting of coagulation tests results and quality assurance of procedures, the personnel and other laboratory resources, as well as on issues related to education and implementation of additional coagulation assays in their laboratory. The survey was administered and data were collected between June and September 2015. Results A total survey response rate was 104/170 (61.2%). Most respondents were faced with incomplete information on prescribed therapy and diagnosis on the test request or inappropriate samples withdrawn on distant locations, but also do not have protocols for handling samples with high haematocrit values. Reporting of PT-INR and D-dimer results was different between laboratories. Although almost all laboratories developed a critical value reporting system, reporting a value to general practitioners is still a problem. Result on coagulation POCT testing showed that not all devices were supervised by laboratories, which is not in compliance with Croatian Chamber of Medical Biochemistry acts. Conclusion Obtained results highlighted areas that need improvement and different practice patterns in particular field of haemostasis testing among laboratories. A harmonization of the overall process of haemostasis testing at national level should be considered and undertaken.

  18. Design of a medical and laboratory equipment management program for the new standards certification achievement in Mexico.

    PubMed

    Franco-Clark, D; Pimentel-Aguilar, A B; Rodriguez-Vera, R

    2010-01-01

    Certification for healthcare institutions in Mexico is ruled by 2009 standards homologated with the Joint Commission International criteria. Nowadays, healthcare requires of medical equipment and devices, so it has become necessary to implement guidelines for its adequate management in order to reach the highest level of quality and safety at the lowest cost. The objective of this work was to develop a Medical and Laboratory Equipment Management Program, oriented to the improvement of quality, effectiveness and efficiency of the technological resources in order to meet the certification requirements. The result of this work allows to have an auto evaluation tool that focuses the efforts of the National Institute for Respiratory Diseases to the achievement of the new requirements established for the certification.

  19. 76 FR 77108 - Airworthiness Directives; International Aero Engines Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Engines Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for International Aero Engines (IAE) V2500-A1... engines. This AD was prompted by three reports of high- pressure turbine (HPT) case burn-through...

  20. Overview of NASA Power Technologies for Space and Aero Applications

    NASA Technical Reports Server (NTRS)

    Beach, Raymond F.

    2014-01-01

    To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both the space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development.

  1. Prevalence and associated factors of Carpal Tunnel Syndrome (CTS) among medical laboratory staff at King Saud University Hospitals, KSA

    PubMed Central

    Ahamed S, Shaffi; Anas M, Bardeesi; Aref A, Altwair; Abdulrahman A, AlMubarak

    2015-01-01

    Background and Objectives: Carpal tunnel syndrome (CTS) is a group of symptoms resulting from local compression of the median nerve at the wrist leading to its subsequent functional impairment and local ischemia of the nerve. Our objective was to determine the prevalence and commonly reported symptoms of CTS in the laboratory workers of King Saud University (KSU) hospitals and to identify the associated variables with CTS. Methods: This was a quantitative observational cross-sectional study which was conducted in KSU hospitals’ laboratories with a total of 225 participants by using a standardized questionnaire known as “ Boston Carpal Tunnel Questionnaire (BCTQ). Data Analysis was carried out by IBM SPSS Statistics software version 21.0. Results: Out of the 225 participants, 57 were found to be severely symptomatic with a prevalence of 25.3%. Among the severely affected participants, females were more than males (58% > 42%) and the difference was statistically significant (p=0.045). Technicians affected (91.2%) were more than attendants (8.8%) and the difference was statistically significant (p=0.042). Conclusion: The prevalence of Carpal tunnel syndrome in KSU hospitals’ medical laboratory staff (25.3%) was close to what was found in literature (21.5%). So laboratory workers are at risk of developing CTS, especially females and technicians with the dominant hand most likely to be affected. PMID:26101485

  2. Blood gas testing and related measurements: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine.

    PubMed

    Dukić, Lora; Kopčinović, Lara Milevoj; Dorotić, Adrijana; Baršić, Ivana

    2016-10-15

    Blood gas analysis (BGA) is exposed to risks of errors caused by improper sampling, transport and storage conditions. The Clinical and Laboratory Standards Institute (CLSI) generated documents with recommendations for avoidance of potential errors caused by sample mishandling. Two main documents related to BGA issued by the CLSI are GP43-A4 (former H11-A4) Procedures for the collection of arterial blood specimens; approved standard - fourth edition, and C46-A2 Blood gas and pH analysis and related measurements; approved guideline - second edition. Practices related to processing of blood gas samples are not standardized in the Republic of Croatia. Each institution has its own protocol for ordering, collection and analysis of blood gases. Although many laboratories use state of the art analyzers, still many preanalytical procedures remain unchanged. The objective of the Croatian Society of Medical Biochemistry and Laboratory Medicine (CSMBLM) is to standardize the procedures for BGA based on CLSI recommendations. The Working Group for Blood Gas Testing as part of the Committee for the Scientific Professional Development of the CSMBLM prepared a set of recommended protocols for sampling, transport, storage and processing of blood gas samples based on relevant CLSI documents, relevant literature search and on the results of Croatian survey study on practices and policies in acid-base testing. Recommendations are intended for laboratory professionals and all healthcare workers involved in blood gas processing.

  3. WHITE COATS AND NO TROUSERS: NARRATING THE EXPERIENCES OF WOMEN TECHNICIANS IN MEDICAL LABORATORIES, 1930-90.

    PubMed

    Hartley, J M; Tansey, E M

    2015-03-20

    Laboratory technicians are a vital part of any working lab. Not only is their knowledge and expertise important for the success of research, but they also often maintain the lab's intellectual and social life. Despite the importance of their work, they are rarely acknowledged in publications, and leave only a few traces within the historical recordthe voices of women laboratory technicians are even harder to uncover. This paper attempts to correct this imbalance by presenting the narratives of women who worked as laboratory technicians at places such as the National Institute for Medical Research (NIMR), the Wellcome Research Laboratories, and established hospital and university labs in Cambridge, Oxford and London. The data were collected though narrative interviews. Specifically, the paper looks at the roles of these women within the lab, their experiences of the social and gender dynamics of the lab, and the development of expertise in regard to the work they carried out and the extent to which they received credit for their contributions to science.

  4. White coats and no trousers: narrating the experiences of women technicians in medical laboratories, 1930–90

    PubMed Central

    Hartley, J. M.; Tansey, E. M.

    2015-01-01

    Laboratory technicians are a vital part of any working lab. Not only is their knowledge and expertise important for the success of research, but they also often maintain the lab's intellectual and social life. Despite the importance of their work, they are rarely acknowledged in publications, and leave only a few traces within the historical record—the voices of women laboratory technicians are even harder to uncover. This paper attempts to correct this imbalance by presenting the narratives of women who worked as laboratory technicians at places such as the National Institute for Medical Research (NIMR), the Wellcome Research Laboratories, and established hospital and university labs in Cambridge, Oxford and London. The data were collected though narrative interviews. Specifically, the paper looks at the roles of these women within the lab, their experiences of the social and gender dynamics of the lab, and the development of expertise in regard to the work they carried out and the extent to which they received credit for their contributions to science. PMID:26489181

  5. Using performance tasks employing IOM patient safety competencies to introduce quality improvement processes in medical laboratory science education.

    PubMed

    Golemboski, Karen; Otto, Catherine N; Morris, Susan

    2013-01-01

    In order to contribute to improved healthcare quality through patient-centered care, laboratory professionals at all levels of practice must be able to recognize the connection between non-analytical factors and laboratory analysis, in the context of patient outcomes and quality improvement. These practices require qualities such as critical thinking (CT), teamwork skills, and familiarity with the quality improvement process, which will be essential for the development of evidence-based laboratory science practice. Performance tasks (PT) are an educational strategy which can be used to teach and assess CT and teamwork, while introducing Medical Laboratory Science (MLS) students at both baccalaureate and advanced-practice levels to the concepts of quality improvement processes and patient outcomes research. PT presents students with complex, realistic scenarios which require the incorporation of subject-specific knowledge with competencies such as effective team communication, patient-centered care, and successful use of information technology. A PT with assessment rubric was designed for use in a baccalaureate-level MLS program to teach and assess CT and teamwork competency. The results indicated that, even when students were able to integrate subject-specific knowledge in creative ways, their understanding of teamwork and quality improvement was limited. This indicates the need to intentionally teach skills such as collaboration and quality system design. PT represent one of many strategies that may be used in MLS education to develop essential professional competencies, encourage expert practice, and facilitate quality improvement.

  6. Blood gas testing and related measurements: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

    PubMed Central

    Dukić, Lora; Kopčinović, Lara Milevoj; Dorotić, Adrijana; Baršić, Ivana

    2016-01-01

    Blood gas analysis (BGA) is exposed to risks of errors caused by improper sampling, transport and storage conditions. The Clinical and Laboratory Standards Institute (CLSI) generated documents with recommendations for avoidance of potential errors caused by sample mishandling. Two main documents related to BGA issued by the CLSI are GP43-A4 (former H11-A4) Procedures for the collection of arterial blood specimens; approved standard – fourth edition, and C46-A2 Blood gas and pH analysis and related measurements; approved guideline – second edition. Practices related to processing of blood gas samples are not standardized in the Republic of Croatia. Each institution has its own protocol for ordering, collection and analysis of blood gases. Although many laboratories use state of the art analyzers, still many preanalytical procedures remain unchanged. The objective of the Croatian Society of Medical Biochemistry and Laboratory Medicine (CSMBLM) is to standardize the procedures for BGA based on CLSI recommendations. The Working Group for Blood Gas Testing as part of the Committee for the Scientific Professional Development of the CSMBLM prepared a set of recommended protocols for sampling, transport, storage and processing of blood gas samples based on relevant CLSI documents, relevant literature search and on the results of Croatian survey study on practices and policies in acid-base testing. Recommendations are intended for laboratory professionals and all healthcare workers involved in blood gas processing. PMID:27812301

  7. Evidence-based approach to the maintenance of laboratory and medical equipment in resource-poor settings.

    PubMed

    Malkin, Robert; Keane, Allison

    2010-07-01

    Much of the laboratory and medical equipment in resource-poor settings is out-of-service. The most commonly cited reasons are (1) a lack of spare parts and (2) a lack of highly trained technicians. However, there is little data to support these hypotheses, or to generate evidence-based solutions to the problem. We studied 2,849 equipment-repair requests (of which 2,529 were out-of-service medical equipment) from 60 resource-poor hospitals located in 11 nations in Africa, Europe, Asia, and Central America. Each piece of equipment was analyzed by an engineer or an engineering student and a repair was attempted using only locally available materials. If the piece was placed back into service, we assumed that the engineer's problem analysis was correct. A total of 1,821 pieces of medical equipment were placed back into service, or 72%, without requiring the use of imported spare parts. Of those pieces repaired, 1,704 were sufficiently documented to determine what knowledge was required to place the equipment back into service. We found that six domains of knowledge were required to accomplish 99% of the repairs: electrical (18%), mechanical (18%), power supply (14%), plumbing (19%), motors (5%), and installation or user training (25%). A further analysis of the domains shows that 66% of the out-of-service equipment was placed back into service using only 107 skills covering basic knowledge in each domain; far less knowledge than that required of a biomedical engineer or biomedical engineering technician. We conclude that a great majority of laboratory and medical equipment can be put back into service without importing spare parts and using only basic knowledge. Capacity building in resource-poor settings should first focus on a limited set of knowledge; a body of knowledge that we call the biomedical technician's assistant (BTA). This data set suggests that a supported BTA could place 66% of the out-of-service laboratory and medical equipment in their hospital back

  8. A Study of Alternate Approaches to Utilization Review of Laboratory Services within an Army Medical Center

    DTIC Science & Technology

    1983-06-06

    Iron, serum; Iron Binding Capacity Acid Phosphatase, Prostatic Fraction Total Alcohol, medical 17-Keto- steriods Al dosterone Lactic Acid Anikacin LOH...serum Glucose Tolerance Test Uric acid, urine HBs AG Uroporphyrlne, urine HCG Vitamin 812 Hydroycortico- steriods (17-OH) VMA (Vanillyl Mandelic Acid

  9. WASTE MINIMIZATION OPPORTUNITY ASSESSMENT: OPTICAL FABRICATION LABORATORY - FITZSIMMONS ARMY MEDICAL CENTER

    EPA Science Inventory

    Under the Waste Reduction Evaluations at Federal Sites (WREAFS) program, RREL has taken the initiative to merge the experience and resources of the EPA with other Federal agencies. At the Fitzsimmons Army Medical Center (FAMC) in Aurora, Colorado, the Army and the EPA cooperated ...

  10. Implementation of ISO guide 25 in a medical dosimetry secondary standards calibration laboratory

    SciTech Connect

    DeWerd, L.A.

    1995-12-31

    Currently, there is a great deal of discussion among industry and government agencies about ISO 9000 accreditation. U.S. manufacturers with ISO 9000 accreditation are regarded more favorably by European countries. The principles behind the ISO 9000 accreditation are based on the Total Quality Management (TQM) principles that are being implemented in many U.S. industries. This paper will deal only with the calibration issue. There is a difference in the areas covered by ISO 9000 and ISO Guide 25 documents. ISO 9000, in particular ISO 9001 - ISO 9003, cover the {open_quotes}calibration{close_quotes} of inspection, measuring and test equipment. This equipment is basically used for {open_quotes}factory calibrations{close_quotes} to determine that equipment is performing within manufacturer specifications. ISO Guide 25 is specifically for {open_quotes}calibration and testing laboratories,{close_quotes} generally laboratories that have painstaking procedures to reduce uncertainties and establish high accuracy of the transfer of calibration. The experience of the University of Wisconsin Accredited Dosimetry Calibration Laboratory in conforming to ISO Guide 25 will be outlined. The entire laboratory staff must become familiar with the process and an individual with direct authority must become the one to maintain the quality of equipment and calibrations in the role of {open_quotes}quality-assurance manager.{close_quotes}

  11. Role-Modeling, Health Promotion, and Disease Prevention for Medical Laboratory Professionals: A Pilot Program.

    ERIC Educational Resources Information Center

    Cornish, James P.

    1985-01-01

    Describes a pilot program designed to prepare models for health promotion and disease prevention through participation in a planned program for the expressed purpose of affecting improvement in the health and health promotion acuity of laboratory professionals, with a plan to expand the concept for use by other hospital employees, and the…

  12. Special-Study Modules in a Problem-Based Learning Medical Curriculum: An Innovative Laboratory Research Practice Supporting Introduction to Research Methodology in the Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Guner, Gul Akdogan; Cavdar, Zahide; Yener, Nilgun; Kume, Tuncay; Egrilmez, Mehtap Yuksel; Resmi, Halil

    2011-01-01

    We describe the organization of wet-lab special-study modules (SSMs) in the Central Research Laboratory of Dokuz Eylul Medical School, Izmir, Turkey with the aim of discussing the scientific, laboratory, and pedagogical aspects of this educational activity. A general introduction to the planning and functioning of these SSMs is given, along with…

  13. The integration of brain dissection within the medical neuroscience laboratory enhances learning.

    PubMed

    Rae, Guenevere; Cork, R John; Karpinski, Aryn C; Swartz, William J

    2016-11-01

    The purpose of this study was to design a one-hour brain dissection protocol for a medical neuroscience course and evaluate the short and long-term effects of its implementation on medical students. First-year medical students (n = 166) participated in a brain dissection activity that included dissection of the basal nuclei and associated deep brain structures. Short-term retention was assessed by administering identical pre- and post-activity tests involving identification of brain structures. Following the brain dissection, the students' posttest scores were significantly higher (68.8% ± 17.8%; mean percent score ± SD) than their pretest scores (35.8% ± 20.0%) (P ≤ 0.0001). Long-term retention was evaluated by conducting an identical assessment five months after completion of the course. Students who participated in the dissection activity (n = 80) had significantly higher scores (46.6% ± 23.8%) than the students who did not participate in the dissection activity (n = 85) (38.1% ± 23.9%) (P ≤ 0.05). In addition to the long-term retention assessment, the NBME(®) Subject Examination scores of students who participated in the dissection activity were significantly higher than the students who did not participate in the dissection activity (P ≤ 0.01). Results suggest that this succinct brain dissection activity may be a practical addition to an undergraduate medical neuroscience course for increasing the effectiveness of neuroanatomy training. This effect may have long-term benefits on knowledge retention and may be correlated with higher performance levels on standardized subject examinations. Anat Sci Educ 9: 565-574. © 2016 American Association of Anatomists.

  14. US Army Medical Bioengineering Research and Development Laboratory Annual Progress Report FY 85. Volume 2.

    DTIC Science & Technology

    1985-10-01

    Bti. This program is directly related to the Laboratory’s mission for research in military vector control. 24. (U) Mosquito larvae ( Aedes aegypti...H-14). Vorgetts, L. J. Factors influencing amplification of Bacillus thuringiensis (serotype H-14) endotoxin in Aedes aegypti larvae. Presentations by...in Aedes aegypti larvae. Proceedings, 72nd Annual Meeting, New Jersey Mosquito Control Association. (In Press) DD FORM 1498 EDITION OF MAR 68 IS

  15. U.S. Army Medical Bioengineering Research and Development Laboratory. Volume 1.

    DTIC Science & Technology

    1986-10-01

    program. In FY86 a systematic study to determine the reliability and validity of tests using sentinel mosquito cages as a bloassay tool was Initiated...During FY86, this Laboratory continued the program In Integrated pest management-mosquitoes by a systematic study to develop methods for mosquito...Entomological Society Association Indian Science Congress -’ American Public Health Association Lepidoptera Research Foundation American Register of

  16. Objective and subjective assessment of reciprocal peer teaching in medical gross anatomy laboratory.

    PubMed

    Bentley, Brian S; Hill, Robert V

    2009-01-01

    Reciprocal peer teaching (RPT), wherein students alternate roles as teacher and learner, has been applied in several educational arenas with varying success. Here, we describe the implementation of a reciprocal peer teaching protocol in a human gross anatomy laboratory curriculum. We compared the outcomes of the RPT class with those of previous classes in which RPT was not employed. Objective data (i.e., course grades) show no significant differences in gross anatomy laboratory grades between students in the RPT and non-RPT classes. To subjectively evaluate the relative success of RPT in the laboratory, we analyzed student opinions obtained through anonymous surveys. These data show that a powerful majority of student respondents felt that RPT was beneficial and should be used in future classes. The greatest disadvantage was unreliable quality of teaching from peers; however, most students still felt that RPT should be continued. Students who felt that they had insufficient hands-on experience (by virtue of dissecting only half the time) were significantly more likely to recommend abandoning RPT. These results underscore the importance of active student dissection, and suggest that a modified version of the described RPT protocol may satisfy more of the needs of large, diverse student populations. Several hidden benefits of RPT exist for faculty, administration, and students, including reduced need for large numbers of cadavers, attendant reduction in operating costs, and smaller student-to-teacher ratios.

  17. US Army Medical Bioengineering Research and Development Laboratory Annual Progress Report FY1981.

    DTIC Science & Technology

    1981-10-01

    Medical Fquipment 11 SCIENTIFIC AND TECNOLOGICAL AREAS* 011-’?400 Bioengineer ing ; 009800 !A-cdiral and Hos )ital F uipment; III STiAT DATE...GENERATED PASSED ON TO THE COMBAT DEVELOPER. WORK HAS ALSO BEEN PERFORMED ON THE PACKAGING OF A FUNCTIONAL MOBILE AID STATION IN A LARGER ARMORED...E. NAME " , 22 CEAWDOD Picto, CA ,.t SRly C,.IICItM C. (U) MOBILE LITTER ;(U) LITTER CARRIER ;(U) WHEELED LITTER ) STANDARD ARMY ITTER . l i A ,.T]AE

  18. A new paradigm for teaching histology laboratories in Canada's first distributed medical school.

    PubMed

    Pinder, Karen E; Ford, Jason C; Ovalle, William K

    2008-01-01

    To address the critical problem of inadequate physician supply in rural British Columbia, The University of British Columbia (UBC) launched an innovative, expanded and distributed medical program in 2004-2005. Medical students engage in a common curriculum at three geographically distinct sites across B.C.: in Vancouver, Prince George and Victoria. The distribution of the core Histology course required a thorough revision of our instructional methodology. We here report our progress and address the question "How does one successfully distribute Histology teaching to remote sites while maintaining the highest of educational standards?" The experience at UBC points to three specific challenges in developing a distributed Histology curriculum: (i) ensuring equitable student access to high quality histological images, (ii) designing and implementing a reliable, state-of-the-art technological infrastructure that allows for real-time teaching and interactivity across geographically separate sites and (iii) ensuring continued student access to faculty content expertise. High quality images--available through any internet connection--are provided within a new virtual slide box library of 300 light microscopic and 190 electron microscopic images. Our technological needs are met through a robust and reliable videoconference system that allows for live, simultaneous communication of audio/visual materials across the three sites. This system also ensures student access to faculty content expertise during all didactic teaching sessions. Student examination results and surveys demonstrate that the distribution of our Histology curriculum has been successful.

  19. SUSCEPTIBILITY TEST FOR FUNGI: CLINICAL AND LABORATORIAL CORRELATIONS IN MEDICAL MYCOLOGY

    PubMed Central

    ALASTRUEY-IZQUIERDO, Ana; MELHEM, Marcia S.C.; BONFIETTI, Lucas X.; RODRIGUEZ-TUDELA, Juan L.

    2015-01-01

    SUMMARY During recent decades, antifungal susceptibility testing has become standardized and nowadays has the same role of the antibacterial susceptibility testing in microbiology laboratories. American and European standards have been developed, as well as equivalent commercial systems which are more appropriate for clinical laboratories. The detection of resistant strains by means of these systems has allowed the study and understanding of the molecular basis and the mechanisms of resistance of fungal species to antifungal agents. In addition, many studies on the correlation of in vitro results with the outcome of patients have been performed, reaching the conclusion that infections caused by resistant strains have worse outcome than those caused by susceptible fungal isolates. These studies have allowed the development of interpretative breakpoints for Candida spp. and Aspergillus spp., the most frequent agents of fungal infections in the world. In summary, antifungal susceptibility tests have become essential tools to guide the treatment of fungal diseases, to know the local and global disease epidemiology, and to identify resistance to antifungals. PMID:26465371

  20. Interest and limits of the six sigma methodology in medical laboratory.

    PubMed

    Scherrer, Florian; Bouilloux, Jean-Pierre; Calendini, Ors'Anton; Chamard, Didier; Cornu, François

    2017-02-01

    The mandatory accreditation of clinical laboratories in France provides an incentive to develop real tools to measure performance management methods and to optimize the management of internal quality controls. Six sigma methodology is an approach commonly applied to software quality management and discussed in numerous publications. This paper discusses the primary factors that influence the sigma index (the choice of the total allowable error, the approach used to address bias) and compares the performance of different analyzers on the basis of the sigma index. Six sigma strategy can be applied to the policy management of internal quality control in a laboratory and demonstrates through a comparison of four analyzers that there is no single superior analyzer in clinical chemistry. Similar sigma results are obtained using approaches toward bias based on the EQAS or the IQC. The main difficulty in using the six sigma methodology lies in the absence of official guidelines for the definition of the total error acceptable. Despite this drawback, our comparison study suggests that difficulties with defined analytes do not vary with the analyzer used.

  1. Embedding measurement within existing computerized data systems: scaling clinical laboratory and medical records heart failure data to predict ICU admission.

    PubMed

    Fisher, William P; Burton, Elizabeth C

    2010-01-01

    This study employs existing data sources to develop a new measure of intensive care unit (ICU) admission risk for heart failure patients. Outcome measures were constructed from laboratory, accounting, and medical record data for 973 adult inpatients with primary or secondary heart failure. Several scoring interpretations of the laboratory indicators were evaluated relative to their measurement and predictive properties. Cases were restricted to tests within first lab draw that included at least 15 indicators. After optimizing the original clinical observations, a satisfactory heart failure severity scale was calibrated on a 0-1000 continuum. Patients with unadjusted CHF severity measures of 550 or less were 2.7 times more likely to be admitted to the ICU than those with higher measures. Patients with low HF severity measures (550 or less) adjusted for demographic and diagnostic risk factors are about six times more likely to be admitted to the ICU than those with higher adjusted measures. A nomogram facilitates routine clinical application. Existing computerized data systems could be programmed to automatically structure clinical laboratory reports using the results of studies like this one to reduce data volume with no loss of information, make laboratory results more meaningful to clinical end users, improve the quality of care, reduce errors and unneeded tests, prevent unnecessary ICU admissions, lower costs, and improve patient satisfaction. Existing data typically examined piecemeal form a coherent scale measuring heart failure severity sensitive to increased likelihood of ICU admission. Marked improvements in ROC curves were found for the aggregate measures relative to individual clinical indicators.

  2. Ka-band MMIC array system for ACTS aeronautical terminal experiment (Aero-X)

    NASA Technical Reports Server (NTRS)

    Raquet, Charles A.; Zakrajsek, Robert J.; Lee, Richard Q.; Andro, Monty; Turtle, John P.

    1995-01-01

    During the summer of 1994, the Advanced Communication Technology Satellite (ACTS) Aeronautical Terminal Experiment (Aero-X) was successfully completed by the NASA Lewis Research Center (LeRC) and the Jet Propulsion Laboratory (JPL). 4.8 and 9.6 Kbps duplex voice links were established between the LeRC Learjet and the ACTS Link Evaluation Terminal (LET) in Cleveland, Ohio, via the ACTS. The antenna system used in this demonstration was developed by LeRC and featured LeRC and US Air Force experimental arrays using GaAs MMIC devices at each radiating element for electronic beam steering and distributed power amplification. The antenna system consisted of three arrays mounted inside the LeRC Learjet, pointing out through the windows. An open loop tracking controller developed by LeRC used information from the aircraft position and attitude sensors to automatically steer the arrays toward ACTS during flight JPL ACTS Mobile Terminal (AMT) system hardware was used as transceivers both on the aircraft and at the LET. The single 32 element MMIC transmit array developed by NASA/LeRC and Texas Instruments has an EIRP of 23.4 dBW at boresight. The two 20 GHz MMIC receive arrays were developed in a cooperative effort with the USAF Rome Laboratory/Electronic System Center, taking advantage of existing USAF array development contracts with Boeing and Martin Marietta. The Boeing array has 23 elements and a G/T of 16/6 db/degK at boresight. The Martin Marietta array has 16 elements and a G/T of 16.1 db/degK at boresight. The three proof-of-concept arrays, the array control system and their integration and operation in the Learjet for Aero-X are described.

  3. [Control of accuracy of immunoserological laboratory data on medical network and standardization].

    PubMed

    Konishi, Keiko

    2003-05-01

    Construction of a medical network for each region and organization has become possible by utilization of information technology. Standardization of the data on the medical network is urgent. Especially, the standardization of immunoserological data is much delayed. In this study, the possibility of standardization of such data was reconsidered based on the findings from various control surveys. Regarding the measurement items for serum concentrations of proteins and other compounds, we concluded that standardization should occur in a manner similar to the method for standardization of biochemical data and accurate control. The data on CRP, IgG, IgA, IgM and AFP, which are determined using the respective standard compound, were converged to a range with inter-facility differences of less than 10% CV. The data on CEA were also converged to achieve an inter-facility difference of less than 10% CV through repeated survey. Automatic measurement for the markers of infection diseases has progressed, and the expression of measurements was changed to the absolute value of COI, U/ml or IU/ml although it was titer in the past. Since these expressions now coexist, it is impossible to standardize the data with absolute qualitative values. It seemed necessary to present them uniformly with qualitative or clinical criteria values or express the presence or absence of infection by a combination of related markers. The measurements obtained from autoantibody-related tests using identical reagent were found coincident, but measurements obtained using different reagents were discrepant and the differences were greater than the sensitivity of measurement. In immunoserological testing and immunochemical testing, it is most important whether the antigen/antibody used as the reagent is the same preparation or not. Therefore, the test should be reconsidered through setting a certain restrictions on each recognition site of epitope and antibody. Thus, we concluded that use of a suitable

  4. Serological Diagnosis of Paracoccidioidomycosis: High Rate of Inter-laboratorial Variability among Medical Mycology Reference Centers

    PubMed Central

    Vidal, Monica Scarpelli Martinelli; Del Negro, Gilda Maria Barbaro; Vicentini, Adriana Pardini; Svidzinski, Teresinha Inez Estivalet; Mendes-Giannini, Maria Jose; Almeida, Ana Marisa Fusco; Martinez, Roberto; de Camargo, Zoilo Pires; Taborda, Carlos Pelleschi; Benard, Gil

    2014-01-01

    Background Serological tests have long been established as rapid, simple and inexpensive tools for the diagnosis and follow-up of PCM. However, different protocols and antigen preparations are used and the few attempts to standardize the routine serological methods have not succeeded. Methodology/Principal findings We compared the performance of six Brazilian reference centers for serological diagnosis of PCM. Each center provided 30 sera of PCM patients, with positive high, intermediate and low titers, which were defined as the “reference” titers. Each center then applied its own antigen preparation and serological routine test, either semiquantitative double immunodifusion or counterimmmunoelectrophoresis, in the 150 sera from the other five centers blindly as regard to the “reference” titers. Titers were transformed into scores: 0 (negative), 1 (healing titers), 2 (active disease, low titers) and 3 (active disease, high titers) according to each center's criteria. Major discordances were considered between scores indicating active disease and scores indicating negative or healing titers; such discordance when associated with proper clinical and other laboratorial data, may correspond to different approaches to the patient's treatment. Surprisingly, all centers exhibited a high rate of “major” discordances with a mean of 31 (20%) discordant scores. Alternatively, when the scores given by one center to their own sera were compared with the scores given to their sera by the remaining five other centers, a high rate of major discordances was also found, with a mean number of 14.8 sera in 30 presenting a discordance with at least one other center. The data also suggest that centers that used CIE and pool of isolates for antigen preparation performed better. Conclusion There are inconsistencies among the laboratories that are strong enough to result in conflicting information regarding the patients' treatment. Renewed efforts should be promoted to improve

  5. Adaptive guidance for an aero-assisted boost vehicle

    NASA Technical Reports Server (NTRS)

    Pamadi, Bandu N.; Taylor, Lawrence W., Jr.; Price, Douglas B.

    1988-01-01

    An adaptive guidance system incorporating dynamic pressure constraint is studied for a single stage to low earth orbit (LEO) aero-assist booster with thrust gimbal angle as the control variable. To derive an adaptive guidance law, cubic spline functions are used to represent the ascent profile. The booster flight to LEO is divided into initial and terminal phases. In the initial phase, the ascent profile is continuously updated to maximize the performance of the boost vehicle enroute. A linear feedback control is used in the terminal phase to guide the aero-assisted booster onto the desired LEO. The computer simulation of the vehicle dynamics considers a rotating spherical earth, inverse square (Newtonian) gravity field and an exponential model for the earth's atmospheric density. This adaptive guidance algorithm is capable of handling large deviations in both atmospheric conditions and modeling uncertainties, while ensuring maximum booster performance.

  6. Fatigue crack monitoring in aero-engines: simulation and experiments

    NASA Astrophysics Data System (ADS)

    Gelman, Leonid M.; Petrunin, Ivan V.; Thompson, Chris

    2004-03-01

    A new genetic approach to fatigue crack monitoring in aero-engine blades is presented. The approach consists of simultaneously using two diagnostic features: the real and imaginary parts of the Fourier transform of vibroacoustical signals. This approach is more fundamental than traditional approaches based on the power spectral density, phase spectrum and Hartley transform; each of these approaches is a special case of the proposed approach. Numerical examples are given based on the processing of signals generated using a nonlinear model of tested blades. The generated signals are the forced vibroacoustical oscillations of cracked and un-cracked blades. The numerical examples show that crack detection ismore effective when using the new approach than when u sing the power spectral density approach. The presented experimental results using un-cracked and cracked turbuine blades from an aero-engine are matched with numerical results. The proposed approach offers an effectiveness improvement over the traditional approach based on power spectral density.

  7. Sensitivity Analysis for Coupled Aero-structural Systems

    NASA Technical Reports Server (NTRS)

    Giunta, Anthony A.

    1999-01-01

    A novel method has been developed for calculating gradients of aerodynamic force and moment coefficients for an aeroelastic aircraft model. This method uses the Global Sensitivity Equations (GSE) to account for the aero-structural coupling, and a reduced-order modal analysis approach to condense the coupling bandwidth between the aerodynamic and structural models. Parallel computing is applied to reduce the computational expense of the numerous high fidelity aerodynamic analyses needed for the coupled aero-structural system. Good agreement is obtained between aerodynamic force and moment gradients computed with the GSE/modal analysis approach and the same quantities computed using brute-force, computationally expensive, finite difference approximations. A comparison between the computational expense of the GSE/modal analysis method and a pure finite difference approach is presented. These results show that the GSE/modal analysis approach is the more computationally efficient technique if sensitivity analysis is to be performed for two or more aircraft design parameters.

  8. Current Challenges for HTCMC Aero-Propulsion Components

    NASA Technical Reports Server (NTRS)

    DiCarlo, James A.; Bansal, Narottam P.

    2007-01-01

    In comparison to the best metallic materials, HTCMC aero-propulsion engine components offer the opportunity of reduced weight and higher temperature operation, with corresponding improvements in engine cooling requirements, emissions, thrust, and specific fuel consumption. Although much progress has been made in the development of advanced HTCMC constituent materials and processes, major challenges still remain for their implementation into these components. The objectives of this presentation are to briefly review (1) potential HTCMC aero-propulsion components and their generic material performance requirements, (2) recent progress at NASA and elsewhere concerning advanced constituents and processes for meeting these requirements, (3) key HTCMC component implementation challenges that are currently being encountered, and (4) on-going activities within the new NASA Fundamental Aeronautics Program that are addressing these challenges.

  9. 2005 PathfinderPlus Aero-Elastic Research Flight

    NASA Technical Reports Server (NTRS)

    Navarro, Robert

    2005-01-01

    This viewgraph presentation describes the 2005 Pathfinder along with an investigation of its aeroelastic responses. The contents include: 1) HALE Class of Vehicles; 2) Aero-elastic Research Flights Overall Objective; 3) General Arrangement; 4) Sensor Locations; 5) NASA Ramp Operations; 6) Lakebed Operations; 7) 1st Flight Data Set; 8) Tool development / data usage; 9) HALE Tool Development & Validation; 10) Building a HALE Foundation; 11) Compelling Needs Drive HALE Efforts; and 12) Team Photo

  10. Studying critical values: adverse event identification following a critical laboratory values study at the ohio state university medical center.

    PubMed

    Jenkins, James J; Mac Crawford, J; Bissell, Michael G

    2007-10-01

    No study to date has used laboratory critical values to evaluate variations in patient adverse events. We retrospectively analyzed a database of critical values to determine their distribution by hospital unit over time. The data were drawn from the Ohio State University Medical Center Information Warehouse (Columbus) for a 58-month period. Critical values were plotted over time on statistical control charts and analyzed for unusual peaks in monthly occurrence rates. Chart review of individual patient results yielded several predictor variables for the unusual peaks. Of these, occurrence of patient adverse events was the most relevant independent predictor variable for a month with an unusual number of critical values vs a normal month. This result epidemiologically confirms the basic premise of critical value reporting and suggests that the control-chart method of this type could be a new statistical tool to compare clinical activity of different hospital locations at different times.

  11. Improvement of the AeroClipper system for cyclones monitoring

    NASA Astrophysics Data System (ADS)

    Vargas, André; Philippe, Duvel Jean

    2016-07-01

    The AeroClipper developed by the French space agency (Centre National d'Études Spatiales, CNES) is a quasi-lagrangian device drifting with surface wind at about 20-30m above the ocean surface. It is a new and original device for real-time and continuous observation of air-sea surface parameters in open ocean remote regions. This device enables the sampling of the variability of surface parameters in particular under convective systems toward which it is attracted. The AeroClipper is therefore an ideal instrument to monitor Tropical Cyclones (TCs) in which they are likely to converge and provide original observations to evaluate and improve our current understanding and diagnostics of TCs as well as their representation in numerical models. In 2008, the AeroClipper demonstrates its capability to be captured by an Ocean Indian cyclone, as two models have converged, without damages, in the eye of Dora cyclone during the 2008 VASCO campaign. This paper will present the improvements of this balloon system for the international project 'the Year of Maritime Continent'.

  12. The Aerospace Medical Research Laboratory: a leader in the development of life support.

    PubMed

    White, S C

    1986-10-01

    The progress in the development of life support for the crewman parallels the changing flight envelope of the airplane and spacecraft. A constant in this history is man. In spite of elaborate attempts to refine the selection of the crew, the basic lists of requirements has not changed. Only the urgency and the need for providing the entire list of requirements have been seen. Generally, progress in the flight envelope has demanded more reliable and often more complex provisions to support the crew. The debate as to how this should be done has often centered on the argument about having man wear or carry the life support elements versus integration of these provisions into the vehicle. This debate initiated the concept of risks/benefits, a debate that has now reached all aspects of man's endeavors, including his medical care. This paper will discuss the major milestones of providing life support, some of the key contributors (a role that General Armstrong played in a great way), and how this has provided the base for the next steps in aviation and space operations.

  13. [Aero-transport of a MDR-TB affected patient with bio-containment systems].

    PubMed

    Lastilla, M; Bisetti, R; Autore, A; Aragonese, F; Di Stefano, M; Sarlo, O

    2007-01-01

    The Italian Air Force medical service, in order to attend to its duty, has to deal with the search, rescue and aero-medical evacuation of the wounded and sick. Due to the increase of air transportation, the likelihood of contracting disease, such as haemorrhagic fevers has risen and it is necessary to know how to treat a patient abroad suffering from severe infectious disease without running any risk either for the medical personnel or for the air crew. The military sanitary service of the Air Force has been preparing for this purpose through a meticulous preparation in Italy and in the USA in order to satisfy these need and through the use of stretchers specifically designed to transport highly contagious patients: Aircraft Transit Isolators (ATIs) and Stretcher Transit Isolators (STIs). These particular medical tools are provided by filter HEPA and they are completely insulated in a PVC envelope. The former (ATI) is used to transport the patient by airplane, the latter is used for road travel. Last January 24th the first real mission was performed transporting a severe TBC-MDR (case) from Alghero to Milan. All went well and the patient left the hospital of Sondalo two months later.

  14. Using qualitative methods to investigate risk perception of Canadian medical laboratory workers in relation to current prion disease infection control policies.

    PubMed

    Buxton, Jane A; Henry, Bonnie; Crabtree, Alexis; Waheed, Aiza; Coulthart, Michael

    2011-01-01

    The aim of this study was to determine the rationale, methodology, and progress of risk perceptions of laboratory workers in relation to existing prion disease infection control policies in Canadian medical laboratories. This study developed a Web survey that investigated the knowledge, behavior, and attitudes of laboratory staff in order to (1) identify strengths, weaknesses, and gaps of current prion infection prevention and control guidelines and (2) inform the development of national medical lab specific guidelines. The use of qualitative methods to develop a relevant survey is described and future research activities are outlined. Preliminary, qualitative data indicate that, among laboratory staff, there is a high degree of perceived susceptibility toward prion transmission in medical laboratories. Significant barriers to following existing prion infection control guidelines are reported with few benefits of following these guidelines. As a result, laboratories take precautions above those that are required when processing suspect prion-infected specimens, which may result in testing delays. A focused survey for laboratory staff that addresses these issues will provide insight on the necessary steps that will ensure safe and efficient diagnostic testing for suspect prion specimens.

  15. Improving communication skill training in patient centered medical practice for enhancing rational use of laboratory tests: The core of bioinformation for leveraging stakeholder engagement in regulatory science.

    PubMed

    Moura, Josemar de Almeida; Costa, Bruna Carvalho; de Faria, Rosa Malena Delbone; Soares, Taciana Figueiredo; Moura, Eliane Perlatto; Chiappelli, Francesco

    2013-01-01

    Requests for laboratory tests are among the most relevant additional tools used by physicians as part of patient's health problemsolving. However, the overestimation of complementary investigation may be linked to less reflective medical practice as a consequence of a poor physician-patient communication, and may impair patient-centered care. This scenario is likely to result from reduced consultation time, and a clinical model focused on the disease. We propose a new medical intervention program that specifically targets improving the patient-centered communication of laboratory tests results, the core of bioinformation in health care. Expectations are that medical students training in communication skills significantly improve physicians-patient relationship, reduce inappropriate use of laboratorial tests, and raise stakeholder engagement.

  16. Paternity analysis based on NGM SElect system in the Medical and Forensic Genetics Laboratory, Department of Forensic Medicine, Medical University of Lodz.

    PubMed

    Markiewicz-Knyziak, B; Jędrzejczyk, M; Bąbol-Pokora, K; Wojtkiewicz, R; Jacewicz, R

    2015-01-01

    The aim of the study was to evaluate the usefulness of the NGM SElect multiplex kit for paternity testing in the population of central Poland, and compare it with the IDENTIFILER system. The study material consisted of buccal swabs taken from individuals who reported to the Medical and Forensic Genetics Laboratory in Lodz. Samples from 450 trio cases of disputed paternity carried out in 2010-2014 were investigated. Genomic DNA was extracted from buccal swabs collected from 1,350 individuals using the Swab kit (A and A Biotechnology) according to the manufacturer's protocol. DNA amplification was performed using the AmpFℓSTR® NGM SelectTM PCR Amplification Kit (Life Technologies). PCR products were separated by capillary electrophoresis using HID 3500 Genetic Analyzer. In the analyzed cases with paternity confirmation in the NGM SElect system, the maximum value of PI was 3.9 × 1012, which corresponds to the probability of paternity W = 99.9999999999%. It was thus significantly higher than analogical parameters obtained in the IDENTIFILER system (PI = 6.0 × 1010, W = 99.99999999%). The NGM SElect kit was unable to resolve just one case out of 450, which represents only 0.2% of all analyzed disputed paternity cases. The study showed the SE33 (ACTBP2) locus to have the highest evidence value in paternity analysis out of all investigated autosomal STRs.

  17. A formative evaluation of problem-based learning as an instructional strategy in a medical laboratory technician course

    NASA Astrophysics Data System (ADS)

    Nelson, Diane Patricia

    2002-09-01

    This study is a formative evaluation of problem-based learning as an effective course delivery strategy in a second year introductory Medical Laboratory Technician discipline-specific hematology course. This strategy can serve two purposes in this type of course: discipline specific content knowledge and process skills learning. A needs study identified that students required additional workplace skills as they entered the clinical internship. Students tested well on the national registry examinations, discipline-specific content knowledge, but group process skills needed improvement in the areas of collaboration, communication, and critical reasoning. Problem-based learning was identified as an change intervention to help provide these skills. A search of the literature revealed that the Baker College cultural and physical environment would support this intervention. Twelve cases were written, situated in a clinical laboratory environment, addressing learning issues identified in a modified Delphi survey of laboratory personnel e.g. fiscal responsibility, turn-around time, invasiveness of laboratory techniques, and holistic view of healthcare environment. A hematology class of 13 students received the intervention. The cases were structured to proceed from instructor-centered (guided) learning issues to learner-centered learning issues. Observations of the in-group collaboration processes were documented, as well as oral presentations and critical reasoning, with students given periodic feedback on these skills. Student surveys provided data about satisfaction, attitude to PBL process, and self-efficacy. Multiple choice discipline-specific content examinations were given and compared with classes from the previous four years. The study found that students receiving the PBL treatment scored as well as or better than students from previous years on traditional multiple choice exams. Recall questions showed positive significance and application/analysis questions

  18. Prevalence of renal and hepatobiliary disease, laboratory abnormalities, and potentially toxic medication exposures among persons with COPD

    PubMed Central

    Mapel, Douglas W; Marton, Jenõ P

    2013-01-01

    Background The purpose of this study was to describe the prevalence of renal and hepatic disease, related laboratory abnormalities, and potentially hepatotoxic and nephrotoxic medication use in a population-based cohort of persons with chronic obstructive pulmonary disease (COPD). Methods This was a retrospective case-control cohort analysis of COPD patients enrolled in one regional health system for at least 12 months during a 36-month study period (n = 2284). Each COPD patient was matched by age and gender to up to three persons not diagnosed with COPD (n = 5959). Results The mean age for cases and controls was 70.3 years, and 52.5% were women. The COPD cohort had significantly higher prevalences (cases/100) of acute, chronic, and unspecified renal failure as compared with controls (1.40 versus 0.59, 2.89 versus 0.79, and 1.09 versus 0.44, respectively). Among the cases, 31.3% had at least one renal or urinary tract diagnosis during the study period, as compared with 21.1% of controls. COPD cases also had more gallbladder disease (2.76 versus 1.63) and pancreatic disease (1.40 versus 0.60), but not hepatic disease. COPD patients were more likely to have at least one serum creatinine level (5.1 versus 2.1) or liver aspartate aminotransferase level (4.5 versus 2.7) that was more than twice the upper limit of normal. COPD patients had prescription fills for an average of 17.6 potentially nephrotoxic and 27.4 hepatotoxic drugs during the study period, as compared with 13.6 and 19.9 for the controls (P value for all comparisons < 0.01). Conclusion COPD patients have a substantially increased prevalence of renal, gallbladder, and pancreatic diseases, as well as abnormal renal and hepatic laboratory values, but not diagnosed liver disease. COPD patients are also more likely to be prescribed medications with potentially toxic renal or hepatic side effects. PMID:23515180

  19. Integrated data acquisition system for medical device testing and physiology research in compliance with good laboratory practices.

    PubMed

    Koenig, Steven C; Woolard, Cary; Drew, Guy; Unger, Lauren; Gillars, Kevin; Ewert, Dan; Gray, Laman; Pantalos, George

    2004-01-01

    In seeking approval from the US Food and Drug Administration (FDA) for clinical trial evaluation of an experimental medical device, a sponsor is required to submit experimental findings and support documentation to demonstrate device safety and efficacy that are in compliance with Good Laboratory Practices (GLP). The objective of this project was to develop an integrated data acquisition (DAQ) system and documentation strategy for monitoring and recording physiological data when testing medical devices in accordance with GLP guidelines mandated by the FDA. Data aquisition systems were developed as stand-alone instrumentation racks containing transducer amplifiers and signal processors, analog-to-digital converters for data storage, visual display and graphical user-interfaces, power conditioners, and test measurement devices. Engineering standard operating procedures (SOP) were developed to provide a written step-by-step process for calibrating, validating, and certifying each individual instrumentation unit and the integrated DAQ system. Engineering staff received GLP and SOP training and then completed the calibration, validation, and certification process for the individual instrumentation components and integrated DAQ system. Eight integrated DAQ systems have been successfully developed that were inspected by regulatory affairs consultants and determined to meet GLP guidelines. Two of these DAQ systems were used to support 40 of the pre-clinical animal studies evaluating the AbiCor artificial heart (ABIOMED, Danvers, MA). Based in part on these pre-clinical animal data, the AbioCor clinical trials began in July 2001. The process of developing integrated DAQ systems, SOP, and the validation and certification methods used to ensure GLP compliance are presented in this article.

  20. Cinacalcet Use Patterns and Effect on Laboratory Values and Other Medications in a Large Dialysis Organization, 2004 through 2006

    PubMed Central

    St. Peter, Wendy L.; Li, Qi; Liu, Jiannong; Persky, Martha; Nieman, Kimberly; Arko, Cheryl; Block, Geoffrey A.

    2009-01-01

    Background and objectives: Cinacalcet was introduced in mid-2004 to treat secondary hyperparathyroidism in dialysis patients. We aimed to characterize adult patients who received cinacalcet prescriptions and to determine (1) dosage titration and effects on laboratory values, active intravenous vitamin D use, and phosphate binder prescriptions and (2) percentage who achieved National Kidney Foundation Kidney Disease Outcomes Quality Initiative targets for serum parathyroid hormone, calcium, and phosphorus and experienced biochemical adverse effects. Design, setting, participants, & measurements: This observational study evaluated 45,487 prevalent patients from a dialysis organization database linked with the Centers for Medicare and Medicaid Services End-Stage Renal Disease database. Patient characteristics, laboratory values (albumin, parathyroid hormone, calcium, phosphorus), intravenous vitamin D, and oral medication (cinacalcet, phosphate binders) prescriptions were evaluated for cinacalcet patients. Results: By June 2006, almost 32% of patients had received cinacalcet prescriptions. Mean baseline corrected calcium was 9.8 mg/dl and phosphorus was 6.3 mg/dl, and median parathyroid hormone was 577 pg/ml, versus 9.5 mg/dl, 5.3 mg/dl, and 215 pg/ml, respectively, for noncinacalcet patients. Patients with cinacalcet prescriptions for ≥6 mo had corrected calcium reduced by 4.2%, phosphorus by 7.0%, and parathyroid hormone by 29.9% by 12 mo. More cinacalcet patients attained Kidney Disease Outcomes Quality Initiative targets with less hyperparathyroidism, hypercalcemia, and hyperphosphatemia but more hypoparathyroidism and hypocalcemia. Over 12 mo, vitamin D use and use consistency increased, phosphate binder dosages increased, and mean cinacalcet daily dosage reached 55 mg. Conclusions: Patients with cinacalcet prescriptions exhibited more severe hyperparathyroidism and hyperphosphatemia than noncinacalcet patients. Positive effects were less dramatic than in Phase

  1. 78 FR 32363 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes AGENCY: Federal Aviation Administration (FAA), Department... propose to rescind an airworthiness directive (AD) for PIAGGIO AERO INDUSTRIES S.p.A. Model P-180...-140, 1200 New Jersey Avenue SE., Washington, DC 20590, between 9 a.m. and 5 p.m., Monday...

  2. 77 FR 35888 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes AGENCY: Federal Aviation Administration (FAA), Department... new airworthiness directive (AD) for PIAGGIO AERO INDUSTRIES S.p.A. Model P-180 airplanes. This...., Washington, DC 20590, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For...

  3. 48 CFR 1852.235-70 - Center for AeroSpace Information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Center for AeroSpace... SPACE ADMINISTRATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1852.235-70 Center for AeroSpace Information. As prescribed in 1835.070(a), insert...

  4. 48 CFR 1852.235-70 - Center for AeroSpace Information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Center for AeroSpace... SPACE ADMINISTRATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1852.235-70 Center for AeroSpace Information. As prescribed in 1835.070(a), insert...

  5. 48 CFR 1852.235-70 - Center for AeroSpace Information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Center for AeroSpace... SPACE ADMINISTRATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1852.235-70 Center for AeroSpace Information. As prescribed in 1835.070(a), insert...

  6. To what extent is clinical and laboratory information used to perform medication reviews in the nursing home setting? the CLEAR study

    PubMed Central

    Mestres Gonzalvo, Carlota; Hurkens, Kim PGM; de Wit, Hugo AJM; van Oijen, Brigit PC; Janknegt, Rob; Schols, Jos MGA; Mulder, Wubbo J; Verhey, Frans R; Winkens, Bjorn; van der Kuy, Paul-Hugo M

    2015-01-01

    Background The aim of this study was to evaluate to what extent laboratory data, actual medication, medical history, and/or drug indication influence the quality of medication reviews for nursing home patients. Methods Forty-six health care professionals from different fields were requested to perform medication reviews for three different cases. Per case, the amount of information provided varied in three subsequent stages: stage 1, medication list only; stage 2, adding laboratory data and reason for hospital admission; and stage 3, adding medical history/drug indication. Following a slightly modified Delphi method, a multidisciplinary team performed the medication review for each case and stage. The results of these medication reviews were used as reference reviews (gold standard). The remarks from the participants were scored, according to their potential clinical impact, from relevant to harmful on a scale of 3 to −1. A total score per case and stage was calculated and expressed as a percentage of the total score from the expert panel for the same case and stage. Results The overall mean percentage over all cases, stages, and groups was 37.0% when compared with the reference reviews. For one of the cases, the average score decreased significantly from 40.0% in stage 1, to 30.9% in stage 2, and 27.9% in stage 3; no significant differences between stages was found for the other cases. Conclusion The low performance, against the gold standard, of medication reviews found in the present study highlights that information is incorrectly used or wrongly interpreted, irrespective of the available information. Performing medication reviews without using the available information in an optimal way can have potential implications for patient safety. PMID:26056459

  7. Virtual and Traditional Slides for Teaching Cellular Morphology to Medical Laboratory Science Undergraduates: A Comparative Study of Performance Outcomes, Retention, and Self-Efficacy Beliefs

    ERIC Educational Resources Information Center

    Solberg, Brooke L.

    2011-01-01

    As a result of massive retirement and educational program expense and closure, the field of Medical Laboratory Science (MLS) is facing a critical workforce shortage. Combatting this issue by increasing undergraduate class size is a difficult proposition due to the intense psychomotor curricular requirements of MLS programs. Technological advances…

  8. Exhaust System Experiments at NASA's AeroAcoustic Propulsion Lab

    NASA Technical Reports Server (NTRS)

    Bridges, James

    2011-01-01

    This presentation gives an overview of the planned testing in the AeroAcoustic Propulsion Lab (AAPL) in the coming 15 months. It was stressed in the presentation that these are plans that are subject to change due to changes in funding and/or programmatic direction. The first chart shows a simplified schedule of test entries with funding sponsor and dates for each. In subsequent charts are pages devoted to the Objectives and Issues with each test entry, along with a graphic intended to represent the test activity. The chart for each test entry also indicates sponsorship of the activity, and a contact person.!

  9. Future NASA Power Technologies for Space and Aero Propulsion Applications

    NASA Technical Reports Server (NTRS)

    Soeder, James F.

    2015-01-01

    To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development. Finally, the presentation examines what type of non-traditional learning areas should be emphasized in student curriculum so that the engineering needs of the third decade of the 21st Century are met.

  10. Unsteady fluid and optical simulation of transonic aero-windows

    NASA Technical Reports Server (NTRS)

    Atwood, Christopher A.

    1993-01-01

    The time-varying fluid and optical fields of several cavity configurations have been computed on overset mesh systems using the Reynolds-averaged Navier-Stokes equations and geometric optics. Comparisons between numerical results and Airborne Optical Adjunct (AOA) flight data are made in two-dimensions for a quieted cavity geometry with two lip-blowing rates. In three-dimensions, two proposed aero-window locations for the Stratospheric Observatory For Infrared Astronomy (SOFIA) are discussed. The simulations indicate that convection of large shear layer structures across the aperture cause the blur circle diameter to be three times the diffraction-limited diameter in the near-infrared band.

  11. Fatigue Life Analysis of Turbine Disks Based on Load Spectra of Aero-engines

    NASA Astrophysics Data System (ADS)

    Li, Yan-Feng; Lv, Zhiqiang; Cai, Wei; Zhu, Shun-Peng; Huang, Hong-Zhong

    2016-04-01

    Load spectra of aero-engines reflect the process of operating aircrafts as well as the changes of parameters of aircrafts. According to flight hours and speed cycle numbers of the aero-engines, the relationship between load spectra and the fatigue life of main components of the aero-engines is obtained. Based on distribution function and a generalized stress-strength interference model, the cumulative fatigue damage of aero-engines is then calculated. After applying the analysis of load spectra and the cumulative fatigue damage theory, the fatigue life of the first-stage turbine disks of the aero-engines is evaluated by using the S-N curve and Miner's rule in this paper.

  12. Interference Analysis Status and Plans for Aeronautical Mobile Airport Communications System (AeroMACS)

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert J.; Wilson, Jeffrey D.

    2010-01-01

    Interference issues related to the operation of an aeronautical mobile airport communications system (AeroMACS) in the C-Band (specifically 5091-5150 MHz) is being investigated. The issue of primary interest is co-channel interference from AeroMACS into mobile-satellite system (MSS) feeder uplinks. The effort is focusing on establishing practical limits on AeroMACS transmissions from airports so that the threshold of interference into MSS is not exceeded. The analyses are being performed with the software package Visualyse Professional, developed by Transfinite Systems Limited. Results with omni-directional antennas and plans to extend the models to represent AeroMACS more accurately will be presented. These models should enable realistic analyses of emerging AeroMACS designs to be developed from NASA Test Bed, RTCA 223, and European results.

  13. Small wind turbine performance evaluation using field test data and a coupled aero-electro-mechanical model

    NASA Astrophysics Data System (ADS)

    Wallace, Brian D.

    A series of field tests and theoretical analyses were performed on various wind turbine rotor designs at two Penn State residential-scale wind-electric facilities. This work involved the prediction and experimental measurement of the electrical and aerodynamic performance of three wind turbines; a 3 kW rated Whisper 175, 2.4 kW rated Skystream 3.7, and the Penn State designed Carolus wind turbine. Both the Skystream and Whisper 175 wind turbines are OEM blades which were originally installed at the facilities. The Carolus rotor is a carbon-fiber composite 2-bladed machine, designed and assembled at Penn State, with the intent of replacing the Whisper 175 rotor at the off-grid system. Rotor aerodynamic performance is modeled using WT_Perf, a National Renewable Energy Laboratory developed Blade Element Momentum theory based performance prediction code. Steady-state power curves are predicted by coupling experimentally determined electrical characteristics with the aerodynamic performance of the rotor simulated with WT_Perf. A dynamometer test stand is used to establish the electromechanical efficiencies of the wind-electric system generator. Through the coupling of WT_Perf and dynamometer test results, an aero-electro-mechanical analysis procedure is developed and provides accurate predictions of wind system performance. The analysis of three different wind turbines gives a comprehensive assessment of the capability of the field test facilities and the accuracy of aero-electro-mechanical analysis procedures. Results from this study show that the Carolus and Whisper 175 rotors are running at higher tip-speed ratios than are optimum for power production. The aero-electro-mechanical analysis predicted the high operating tip-speed ratios of the rotors and was accurate at predicting output power for the systems. It is shown that the wind turbines operate at high tip-speeds because of a miss-match between the aerodynamic drive torque and the operating torque of the wind

  14. AeroVironment technician checks a Helios solar cell panel

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A technician at AeroVironment's Design Development Center in Simi Valley, California, checks a panel of silicon solar cells for conductivity and voltage. The bi-facial cells, fabricated by SunPower, Inc., of Sunnyvale, California, are among 64,000 solar cells which have been installed on the Helios Prototype solar-powered aircraft to provide power to its 14 electric motors and operating systems. Developed by AeroVironment under NASA's Environmental Research Aircraft and Sensor Technology (ERAST) project, the Helios Prototype is the forerunner of a planned fleet of slow-flying, long duration, high-altitude aircraft which can perform atmospheric science missions and serve as telecommunications relay platforms in the stratosphere. Target goals set by NASA for the giant 246-foot span flying wing include reaching and sustaining subsonic horizontal flight at 100,000 feet altitude in 2001, and sustained continuous flight for at least four days and nights above 50,000 feet altitude with the aid of a regenerative fuel cell-based energy storage system now under development in 2003.

  15. Overview of additive manufacturing activities at MTU aero engines

    NASA Astrophysics Data System (ADS)

    Bamberg, Joachim; Dusel, Karl-Heinz; Satzger, Wilhelm

    2015-03-01

    Additive Manufacturing (AM) is a promising technology to produce parts easily and effectively, just by using metallic powder or wire as starting material and a sophisticated melting process. In contrast to milling or turning technologies complex shaped and hollow parts can be built up in one step. That reduces the production costs and allows the implementation of complete new 3D designs. Therefore AM is also of great interest for aerospace and aero engine industry. MTU Aero Engines has focused its AM activities to the selective laser melting technique (SLM). This technique uses metallic powder and a laser for melting and building up the part layer by layer. It is shown which lead part was selected for AM and how the first production line was established. A special focus is set on the quality assurance of the selective laser melting process. In addition to standard non-destructive inspection techniques a new online monitoring tool was developed and integrated into the SLM machines. The basics of this technique is presented.

  16. Spectral Behavior of Weakly Compressible Aero-Optical Distortions

    NASA Astrophysics Data System (ADS)

    Mathews, Edwin; Wang, Kan; Wang, Meng; Jumper, Eric

    2016-11-01

    In classical theories of optical distortions by atmospheric turbulence, an appropriate and key assumption is that index-of-refraction variations are dominated by fluctuations in temperature and the effects of turbulent pressure fluctuations are negligible. This assumption is, however, not generally valid for aero-optical distortions caused by turbulent flow over an optical aperture, where both temperature and pressures fluctuations may contribute significantly to the index-of-refraction fluctuations. A general expression for weak fluctuations in refractive index is derived using the ideal gas law and Gladstone-Dale relation and applied to describe the spectral behavior of aero-optical distortions. Large-eddy simulations of weakly compressible, temporally evolving shear layers are then used to verify the theoretical results. Computational results support theoretical findings and confirm that if the log slope of the 1-D density spectrum in the inertial range is -mρ , the optical phase distortion spectral slope is given by - (mρ + 1) . The value of mρ is then shown to be dependent on the ratio of shear-layer free-stream densities and bounded by the spectral slopes of temperature and pressure fluctuations. Supported by HEL-JTO through AFOSR Grant FA9550-13-1-0001 and Blue Waters Graduate Fellowship Program.

  17. A 2μm-pump laser-based DIRCM system and aero-optics in the mid-IR

    NASA Astrophysics Data System (ADS)

    Renz, Günther; Bohn, Willy

    2007-10-01

    The improvement of the security of platforms (aircrafts) with countermeasure techniques in the mid-IR especially in the take-off or landing phase is nowadays more stringent due to upcoming threats. We report on the development of a Tm:YLF-fiber laser (1.908 μm) pumped Ho:YAG (2.09 µm) high energy laser system with pulse energies up to 100 mJ at pulse lengths close to 20 ns and repetition rates of 100 Hz. A high quality laser beam leaving a platform through a variable-index-of-refraction airflow will experience wave-front aberrations and consequently lose its ability to be perfectly focused in the far field. Two main causes of laser beam degradations are issued in this investigation. First, there is the degradation immediately around the fuselage, referred to aero-optic problems and second the atmospheric propagation influence via air turbulence. The aero-optic influence on the laser beam degradation will be investigated in a laboratory experimental approach with a mid-IR laser beam traversing a transonic free air stream relevant to a real air flow around a fuselage. The propagation characteristics of a laser beam passing turbulent air will be numerically simulated with a multiple phase-screen method and a Fourier propagation technique. Different turbulence degrees relevant to propagation directions especially behind aircrafts will be considered.

  18. 21 CFR 862.2050 - General purpose laboratory equipment labeled or promoted for a specific medical use.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... human body and that is labeled or promoted for a specific medical use. (b) Classification. Class I..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND...

  19. 21 CFR 862.2050 - General purpose laboratory equipment labeled or promoted for a specific medical use.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... human body and that is labeled or promoted for a specific medical use. (b) Classification. Class I..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND...

  20. A coupled-adjoint method for high-fidelity aero-structural optimization

    NASA Astrophysics Data System (ADS)

    Martins, Joaquim Rafael Rost A.

    A new integrated aero-structural design method for aerospace vehicles is presented. The approach combines an aero-structural analysis solver, a coupled aero-structural adjoint solver, a geometry engine, and an efficient gradient-based optimization algorithm. The aero-structural solver ensures accurate solutions by using high-fidelity models for the aerodynamics, structures, and coupling procedure. The coupled aero-structural adjoint solver is used to calculate the sensitivities of aerodynamic and structural cost functions with respect to both aerodynamic shape and structural variables. The aero-structural adjoint sensitivities are compared with those given by the complex-step derivative approximation and finite differences. The proposed method is shown to be both accurate and efficient, exhibiting a significant cost advantage when the gradient of a small number of functions with respect to a large number of design variables is needed. The optimization of a supersonic business jet configuration demonstrates the usefulness and importance of computing aero-structural sensitivities using the coupled-adjoint method.

  1. Miga Aero Actuator and 2D Machined Mechanical Binary Latch

    NASA Technical Reports Server (NTRS)

    Gummin, Mark A.

    2013-01-01

    Shape memory alloy (SMA) actuators provide the highest force-to-weight ratio of any known actuator. They can be designed for a wide variety of form factors from flat, thin packages, to form-matching packages for existing actuators. SMA actuators can be operated many thousands of times, so that ground testing is possible. Actuation speed can be accurately controlled from milliseconds to position and hold, and even electronic velocity-profile control is possible. SMA actuators provide a high degree of operational flexibility, and are truly smart actuators capable of being accurately controlled by onboard microprocessors across a wide range of voltages. The Miga Aero actuator is a SMA actuator designed specifically for spaceflight applications. Providing 13 mm of stroke with either 20- or 40-N output force in two different models, the Aero actuator is made from low-outgassing PEEK (polyether ether ketone) plastic, stainless steel, and nickel-titanium SMA wires. The modular actuator weighs less than 28 grams. The dorsal output attachment allows the Aero to be used in either PUSH or PULL modes by inverting the mounting orientation. The SPA1 actuator utilizes commercially available SMA actuator wire to provide 3/8-in. (approx. =.1 cm) of stroke at a force of over 28 lb (approx. = .125 N). The force is provided by a unique packaging of the single SMA wire that provides the output force of four SMA wires mechanically in parallel. The output load is shared by allowing the SMA wire to slip around the output attachment end to adjust or balance the load, preventing any individual wire segment from experiencing high loads during actuation. A built-in end limit switch prevents overheating of the SMA element following actuation when used in conjunction with the Miga Analog Driver [a simple MOSFET (metal oxide semiconductor field-effect transistor) switching circuit]. A simple 2D machined mechanical binary latch has been developed to complement the capabilities of SMA wire

  2. The Modular Aero-Propulsion System Simulation (MAPSS) Users' Guide

    NASA Technical Reports Server (NTRS)

    Parker, Khary I.; Melcher, Kevin J.

    2004-01-01

    The Modular Aero-Propulsion System Simulation is a flexible turbofan engine simulation environment that provides the user a platform to develop advanced control algorithms. It is capable of testing the performance of control designs on a validated and verified generic engine model. In addition, it is able to generate state-space linear models of the engine model to aid in controller design. The engine model used in MAPSS is a generic high-pressure ratio, dual-spool, lowbypass, military-type, variable cycle turbofan engine with a digital controller. MAPSS is controlled by a graphical user interface (GUI) and this guide explains how to use it to take advantage of the capabilities of MAPSS.

  3. Aero-acoustics of Drag Generating Swirling Exhaust Flows

    NASA Technical Reports Server (NTRS)

    Shah, P. N.; Mobed, D.; Spakovszky, Z. S.; Brooks, T. F.; Humphreys, W. M. Jr.

    2007-01-01

    Aircraft on approach in high-drag and high-lift configuration create unsteady flow structures which inherently generate noise. For devices such as flaps, spoilers and the undercarriage there is a strong correlation between overall noise and drag such that, in the quest for quieter aircraft, one challenge is to generate drag at low noise levels. This paper presents a rigorous aero-acoustic assessment of a novel drag concept. The idea is that a swirling exhaust flow can yield a steady, and thus relatively quiet, streamwise vortex which is supported by a radial pressure gradient responsible for pressure drag. Flows with swirl are naturally limited by instabilities such as vortex breakdown. The paper presents a first aero-acoustic assessment of ram pressure driven swirling exhaust flows and their associated instabilities. The technical approach combines an in-depth aerodynamic analysis, plausibility arguments to qualitatively describe the nature of acoustic sources, and detailed, quantitative acoustic measurements using a medium aperture directional microphone array in combination with a previously established Deconvolution Approach for Mapping of Acoustic Sources (DAMAS). A model scale engine nacelle with stationary swirl vanes was designed and tested in the NASA Langley Quiet Flow Facility at a full-scale approach Mach number of 0.17. The analysis shows that the acoustic signature is comprised of quadrupole-type turbulent mixing noise of the swirling core flow and scattering noise from vane boundary layers and turbulent eddies of the burst vortex structure near sharp edges. The exposed edges are the nacelle and pylon trailing edge and the centerbody supporting the vanes. For the highest stable swirl angle setting a nacelle area based drag coefficient of 0.8 was achieved with a full-scale Overall Sound Pressure Level (OASPL) of about 40dBA at the ICAO approach certification point.

  4. Technical Note: Simulation of detailed aerosol chemistry on the global scale using MECCA-AERO

    NASA Astrophysics Data System (ADS)

    Kerkweg, A.; Sander, R.; Tost, H.; Jöckel, P.; Lelieveld, J.

    2007-06-01

    We present the MESSy submodel MECCA-AERO, which simulates both aerosol and gas phase chemistry within one comprehensive mechanism. Including the aerosol phase into the chemistry mechanism increases the stiffness of the resulting set of differential equations. The numerical aspects of the approach followed in MECCA-AERO are presented. MECCA-AERO requires input of an aerosol dynamical/microphysical model to provide the aerosol size and particle number information of the modes/bins for which the chemistry is explicitly calculated. Additional precautions are required to avoid the double counting of processes, especially for sulphate in the aerosol dynamical and the chemistry model. This coupling is explained in detail. To illustrate the capabilities of the new aerosol submodel, examples for species usually treated in aerosol dynamical models are shown. The aerosol chemistry as provided by MECCA-AERO is very sumptuous and not readily applicable for long-term simulations, though it provides a reference to evaluate simplified approaches.

  5. Technical Note: simulation of detailed aerosol chemistry on the global scale using MECCA-AERO

    NASA Astrophysics Data System (ADS)

    Kerkweg, A.; Sander, R.; Tost, H.; Jöckel, P.; Lelieveld, J.

    2007-03-01

    We present the MESSy submodel MECCA-AERO, which simulates both aerosol and gas phase chemistry with the same mechanism. Including the aerosol phase into the chemistry mechanism increases the stiffness of the resulting set of differential equations. The numerical aspects of the approach followed in MECCA-AERO are presented. MECCA-AERO requires input of an aerosol dynamical/microphysical model to provide the aerosol size and particle number information of the modes/bins for which the chemistry is explicitly calculated. Additional precautions are required to avoid the double counting of processes, especially for sulphate in the aerosol dynamical and the chemistry model. This coupling is explained in detail. To illustrate the capabilities of the new aerosol submodel, examples for species usually treated in aerosol dynamical models are shown. The aerosol chemistry as provided by MECCA-AERO is very sumptuous and not readily applicable for long-term simulations, though it provides a reference to evaluate simplified approaches.

  6. 21 CFR 862.2050 - General purpose laboratory equipment labeled or promoted for a specific medical use.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... human body and that is labeled or promoted for a specific medical use. (b) Classification. Class I..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL... quality system regulation in part 820 of this chapter, with the exception of § 820.180, with respect...

  7. Aero-Thermal Calibration of the NASA Glenn Icing Research Tunnel (2012 Tests)

    NASA Technical Reports Server (NTRS)

    Pastor-Barsi, Christine; Allen, Arrington E.

    2013-01-01

    A full aero-thermal calibration of the NASA Glenn Icing Research Tunnel (IRT) was completed in 2012 following the major modifications to the facility that included replacement of the refrigeration plant and heat exchanger. The calibration test provided data used to fully document the aero-thermal flow quality in the IRT test section and to construct calibration curves for the operation of the IRT.

  8. Development and Use of Mark Sense Record Cards for Recording Medical Data on Pilots Subjected to Acceleration Stress

    NASA Technical Reports Server (NTRS)

    Smedal, Harald A.; Havill, C. Dewey

    1962-01-01

    A TIME-HONORED system of recording medical histories and the data obtained on physical and laboratory examination has been that of writing the information on record sheets that go into a folder for each patient. In order to have information which would be more readily retrieved, 'a program was initiated in 1952 by the U. S. Naval School of Aviation Medicine in connection with their "Care of the Flyer" study to place this information on machine record cards. In 1958, a machine record card method was developed for recording medical data in connection with the astronaut selection program. Machine record cards were also developed by the Aero Medical Laboratory, Wright-Patterson AFB, Ohio, and the Aviation Medical Acceleration Laboratory, Naval Air Development Center, Johnsville, Pennsylvania, for use in connection with a variety of tests including acceleration stress.1 Therefore, a variety of systems resulted in which data of a medical nature could easily be recalled. During the NASA, Ames Research Center centrifuge studies/'S the pilot subjects were interviewed after each centrifuge run, or series of runs, and subjective information was recorded in a log book by the usual history taking methods referred to above. After the methods Were reviewed, it' was recognized that a card system would be very useful in recording data from our pilots after they had been exposed to acceleration stress. Since the acceleration stress cards already developed did not meet our requirements, it was decided a different card was needed.

  9. Dynamic finite element model validation of an assembled aero-engine casing

    NASA Astrophysics Data System (ADS)

    Huang, Zi; Zang, Chaoping; Jiang, Yuying; Wang, Xiaowei

    2016-09-01

    Structural dynamic model updating and validation of an aero-engine casing is critical to the design and development of an aircraft engine. It helps to identify the dynamic characteristics and reduce the response of the aero-engine. The modelling and parameter identification of joint are extremely difficult and important in structural dynamic analysis of the assembled aero-engine casing. In this paper, dynamic model validation technique was applied to update and validate the finite element model of an assembled aero-engine casing. First, modal test of individual casings and the assembled casing was performed by using the traditional acceleration sensors and a hammer. The modal frequencies and mode shapes were obtained by modal analysis tools. Second, the Inverse Eigen-sensitivity Method was used to correct frequency errors and MAC values of correlated mode pairs in the individual components to obtain validated models. Last, the bolt joints of two aero-engine casings were modelled by thin layer of shell elements. The material parameters or element properties of the thin-layer contact elements were updated to obtain reliable connection parameters. The results show that the errors of natural frequencies between the validated FE model of an assembled aero-engine casing and test data are within 7%, and the MAC values of main modes are above 70%, which can verify the feasibility and effectiveness of this approach.

  10. Considerations for Improving the Capacity and Performance of AeroMACS

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert J.; Kamali, Behnam; Apaza, Rafael D.; Wilson, Jeffrey D.; Dimond, Robert P.

    2014-01-01

    The Aeronautical Mobile Airport Communications System (AeroMACS) has progressed from concept through prototype development, testing, and standards development and is now poised for the first operational deployments at nine US airports by the Federal Aviation Administration. These initial deployments will support fixed applications. Mobile applications providing connectivity to and from aircraft and ground-based vehicles on the airport surface will occur at some point in the future. Given that many fixed applications are possible for AeroMACS, it is necessary to now consider whether the existing capacity of AeroMACS will be reached even before the mobile applications are ready to be added, since AeroMACS is constrained by both available bandwidth and transmit power limitations. This paper describes some concepts that may be applied to improve the future capacity of AeroMACS, with a particular emphasis on gains that can be derived from the addition of IEEE 802.16j multihop relays to the AeroMACS standard, where a significant analysis effort has been undertaken.

  11. BACLAB: A Computer Simulation of a Medical Bacteriology Laboratory--An Aid for Teaching Tertiary Level Microbiology.

    ERIC Educational Resources Information Center

    Lewington, J.; And Others

    1985-01-01

    Describes a computer simulation program which helps students learn the main biochemical tests and profiles for identifying medically important bacteria. Also discusses the advantages and applications of this type of approach. (ML)

  12. Role and Responsibilities of Laboratory Medicine Specialists in the Verification OF Metrological Traceability of in vitro Medical Diagnostics

    PubMed Central

    Braga, Federica; Infusino, Ilenia; Panteghini, Mauro

    2015-01-01

    Summary To be accurate and equivalent, laboratory results should be traceable to higher-order references. Furthermore, their quality should fulfill acceptable measurement uncertainty as defined to fit the intended clinical use. With this aim, in vitro diagnostics (IVD) manufacturers should define a calibration hierarchy to assign traceable values to their system calibrators and to fulfill during this process uncertainty limits for calibrators, which should represent a proportion of the uncertainty budget allowed for clinical laboratory results. It is therefore important that, on one hand, the laboratory profession clearly defines the clinically acceptable uncertainty for relevant tests and, on the other hand, end-users may know and verify how manufacturers have implemented the traceability of their calibrators and estimated the corresponding uncertainty. Important tools for IVD traceability surveillance are quality control programmes through the daily verification by clinical laboratories that control materials of analytical systems are in the manufacturer’s declared validation range [Internal Quality Control (IQC) component I] and the organization of External Quality Assessment Schemes meeting metrological criteria. In a separate way, clinical laboratories should also monitor the reliability of employed commercial systems through the IQC component II, devoted to estimation of the measurement uncertainty due to random effects, which includes analytical system imprecision together with individual laboratory performance in terms of variability. PMID:28356838

  13. [Importance of information from the Department of Clinical Laboratory in the treatment of infectious diseases--from the viewpoint of medical safety].

    PubMed

    Kondo, Shigemi; Miida, Takashi

    2012-10-01

    For the report of microbiological laboratory staff to be made more effective, developments of the entire support systems regarding hospital infection control are essential. Therefore, it should be carried out side by side with the development of a guideline support system, proper antibiotic use, a consultation system, as well as education and training of medical staff. As measures of the Department of Clinical Laboratory, antibiograms are conducted periodically and a blood culture report is taken as a 24-hour system. In addition, the blood culture report is transmitted to ensure that the attending physician performs activities according to the electronic medical records as well as through contact by telephone. In addition, the ICD reported during the day on behalf of the laboratory technician, at the stage of the first report, and the estimation of bacterial species and suggestions for additional testing were performed. For the measures described above, the current rate of two sets of blood cultures taken comprises over 90%. In addition, the use of carbapenems was reduced by half. As the result, the rate of imipenem-resistant Pseudomonas aeruginosa was reduced by about 40% in 2006 to 20% in 2010, and the development of multi-drug resistant bacteria was markedly reduced.

  14. AeroCOM Biomass Burning Emissions Experiment-Overview

    NASA Astrophysics Data System (ADS)

    Petrenko, M. M.; Chin, M.; Kahn, R. A.; Val Martin, M.

    2014-12-01

    Biomass burning (BB) is one of the major sources of optically and chemically potent carbonaceous aerosols, gaseous aerosol precursors, and volatile organic compounds. It is, therefore, important to represent these emissions as accurately as possible in the global and regional models. To correctly simulate BB emissions from a fire, the model needs two key inputs: emission source strength for the fire and the emission injection height. Based on pilot studies of injection height by M. Val Martin et al. (2010, 2012), and of source strength by M. Petrenko et al. (2012), we proposed an AeroCom-coordinated multi-model BB experiment. The core objectives of the experiment are: To inter-compare and quantify the accuracy and diversity of the AeroCom model simulated BB AOD using a common emissions inventory. To propose a region-by-region emission correction scheme based on the comparisons of model output with satellite snapshots of smoke-plume optical depth from the MODIS and MISR instruments. This will allow us to bring the widely used GFED v3 emissions inventory to the levels needed to improve model-observation comparisons. To test smoke injection height-emission intensity relationships used in global models against MISR multi-angle smoke-plume-height retrievals. With the first stage of the BB experiment focused on the source strength, this talk will provide an update on development and testing the method of using satellite-measured aerosol optical depth snapshots to constrain BB aerosol emissions in the global models. The global datasets of fire-and-smoke events, observed by MISR and MODIS during 2006, 2007 and 2008, to be used for model-satellite comparisons, will also be described. These events were selected according to a number of criteria to be suitable for model-observation comparison at the scales of global model resolution. In addition, we will showcase preliminary results of model inter-comparisons within the BB experiment, outline plans for future output analysis

  15. [The system of quality management in medical laboratory: the problematic issues of implementation of GOST RKS 9001-2008, GOST R ISO 15189-2009 and GOST R ISO 53079-2008].

    PubMed

    Dolgikh, T I

    2013-04-01

    The article presents the approaches to development and implementation of system of quality management in laboratory as an integral part of the given system in whole medical institution. The costs of works execution concerning quality support are to be weighted with economic profitability and timeliness of medical care provision to ill people considering pre-analytic stage (out-laboratory and in-laboratory) laboratory analysis. Factually it is a matter of development of system of balanced indicators concerning quality management of institution and laboratory functioning. The problematic issues are presented concerning maintenance of particular requirements of GOSTR ISO 15189 about quality of production. The emphasis is made on the necessity of training of administrations of laboratories in the field of quality management and economics of laboratory business.

  16. Factors affecting job satisfaction and retention of medical laboratory professionals in seven countries of Sub-Saharan Africa.

    PubMed

    Marinucci, Francesco; Majigo, Mtebe; Wattleworth, Matthew; Paterniti, Antonio Damiano; Hossain, Mian Bazle; Redfield, Robert

    2013-08-17

    Effective implementation and sustainability of quality laboratory programmes in Sub-Saharan Africa relies on the development of appropriate staff retention strategies. Assessing the factors responsible for job satisfaction and retention is key for tailoring specific interventions aiming at improving the overall impact of health programmes. A survey was developed to assess these factors among 224 laboratorians working in the laboratory programme the University of Maryland implemented in seven Sub-Saharan African countries. Lack of professional development was the major reason for leaving the previous job for 28% of interviewees who changed jobs in the past five years. Professional development/training opportunities was indicated by almost 90% (195/224) of total interviewees as the most important or a very important factor for satisfaction at their current job. Similarly, regular professional development/opportunities for training was the highest rated incentive to remain at their current job by 80% (179/224). Laboratory professionals employed in the private sector were more likely to change jobs than those working in the public sector (P = 0.002). The findings were used for developing specific strategies for human resources management, in particular targeting professional development, aiming at improving laboratory professionals within the University of Maryland laboratory programme and hence its long-term sustainability.

  17. Medical expert systems developed in j.MD, a Java based expert system shell: application in clinical laboratories.

    PubMed

    Van Hoof, Viviane; Wormek, Arno; Schleutermann, Sylvia; Schumacher, Theo; Lothaire, Olivier; Trendelenburg, Christian

    2004-01-01

    Growing complexity of diagnostic tests, combined with increased workload, stringent laboratory accreditation demands, continuous shortening of turn-around-time and budget restrictions have forced laboratories to automate most of their iterative tasks. Introduction of artificial intelligence by means of expert systems has gained an important place in this automation process. Different parts of clinical laboratory activity can benefit from their implementation and the present project deals with one aspect, namely the clinical interpretation of diagnostic tests. This paper describes how j.MD, a new Java based expert system shell, was used to reprogram the expert system for interpretation of amylase isoenzyme patterns that has been in use for many years in our laboratory, and that was originally programmed in Pro.MD, a Prolog based expert system shell. One of the most important advantages of the j.MD system is its bidirectional link with the laboratory information system. This project shows how expert systems for the interpretation of complex diagnostic tests that demand specific expertise can become an integrated part of the automated clinical chemistry lab.

  18. Factors affecting job satisfaction and retention of medical laboratory professionals in seven countries of Sub-Saharan Africa

    PubMed Central

    2013-01-01

    Effective implementation and sustainability of quality laboratory programmes in Sub-Saharan Africa relies on the development of appropriate staff retention strategies. Assessing the factors responsible for job satisfaction and retention is key for tailoring specific interventions aiming at improving the overall impact of health programmes. A survey was developed to assess these factors among 224 laboratorians working in the laboratory programme the University of Maryland implemented in seven Sub-Saharan African countries. Lack of professional development was the major reason for leaving the previous job for 28% of interviewees who changed jobs in the past five years. Professional development/training opportunities was indicated by almost 90% (195/224) of total interviewees as the most important or a very important factor for satisfaction at their current job. Similarly, regular professional development/opportunities for training was the highest rated incentive to remain at their current job by 80% (179/224). Laboratory professionals employed in the private sector were more likely to change jobs than those working in the public sector (P = 0.002). The findings were used for developing specific strategies for human resources management, in particular targeting professional development, aiming at improving laboratory professionals within the University of Maryland laboratory programme and hence its long-term sustainability. PMID:23958152

  19. Creation and maintenance of helix, a Web based database of medical genetics laboratories, to serve the needs of the genetics community.

    PubMed Central

    Tarczy-Hornoch, P.; Covington, M. L.; Edwards, J.; Shannon, P.; Fuller, S.; Pagon, R. A.

    1998-01-01

    Helix (healthlinks.washington.edu/helix) is a web accessible database that serves as the main U.S. directory of laboratories offering genetic testing. The database was designed to address the previously unmet need for a centralized, continuously updated source of information about clinical and research genetic testing to keep pace with the rapid rate of gene discovery resulting from the Human Genome Project. The Helix project began in 1992 at the University of Washington and Children's Hospital and Regional Medical Center. It has evolved from a single user stand alone relational database to a fully Web enabled database queried and maintained via the web and linked to other web accessible genomic databases. As of February, 1998 it lists more than 500 diseases and 290 laboratories, with over 5,200 registered users making approximately 250 queries/day (90% via the Internet). We describe the iterative design, implementation, population and assessment of the database over a six year period. PMID:9929238

  20. Multidisciplinary Design Optimization on Conceptual Design of Aero-engine

    NASA Astrophysics Data System (ADS)

    Zhang, Xiao-bo; Wang, Zhan-xue; Zhou, Li; Liu, Zeng-wen

    2016-06-01

    In order to obtain better integrated performance of aero-engine during the conceptual design stage, multiple disciplines such as aerodynamics, structure, weight, and aircraft mission are required. Unfortunately, the couplings between these disciplines make it difficult to model or solve by conventional method. MDO (Multidisciplinary Design Optimization) methodology which can well deal with couplings of disciplines is considered to solve this coupled problem. Approximation method, optimization method, coordination method, and modeling method for MDO framework are deeply analyzed. For obtaining the more efficient MDO framework, an improved CSSO (Concurrent Subspace Optimization) strategy which is based on DOE (Design Of Experiment) and RSM (Response Surface Model) methods is proposed in this paper; and an improved DE (Differential Evolution) algorithm is recommended to solve the system-level and discipline-level optimization problems in MDO framework. The improved CSSO strategy and DE algorithm are evaluated by utilizing the numerical test problem. The result shows that the efficiency of improved methods proposed by this paper is significantly increased. The coupled problem of VCE (Variable Cycle Engine) conceptual design is solved by utilizing improved CSSO strategy, and the design parameter given by improved CSSO strategy is better than the original one. The integrated performance of VCE is significantly improved.

  1. Commercial Modular Aero-Propulsion System Simulation 40k

    NASA Technical Reports Server (NTRS)

    Guo, Ten-Huei; Lavelle, Thomas; Litt, Jonathan; Csank, Jeffrey; May, Ryan

    2011-01-01

    The Commercial Modular Aero-Propulsion System Simulation 40k (CMAPSS40k) software package is a nonlinear dynamic simulation of a 40,000-pound (approximately equals 178-kN) thrust class commercial turbofan engine, written in the MATLAB/Simulink environment. The model has been tuned to capture the behavior of flight test data, and is capable of running at any point in the flight envelope [up to 40,000 ft (approximately equals 12,200 m) and Mach 0.8]. In addition to the open-loop engine, the simulation includes a controller whose architecture is representative of that found in industry. C-MAPSS40k fills the need for an easy-to-use, realistic, transient simulation of a medium-size commercial turbofan engine with a representative controller. It is a detailed component level model (CLM) written in the industry-standard graphical MATLAB/Simulink environment to allow for easy modification and portability. At the time of this reporting, no other such model exists in the public domain.

  2. Dynamic performance of an aero-assist spacecraft - AFE

    NASA Technical Reports Server (NTRS)

    Chang, Ho-Pen; French, Raymond A.

    1992-01-01

    Dynamic performance of the Aero-assist Flight Experiment (AFE) spacecraft was investigated using a high-fidelity 6-DOF simulation model. Baseline guidance logic, control logic, and a strapdown navigation system to be used on the AFE spacecraft are also modeled in the 6-DOF simulation. During the AFE mission, uncertainties in the environment and the spacecraft are described by an error space which includes both correlated and uncorrelated error sources. The principal error sources modeled in this study include navigation errors, initial state vector errors, atmospheric variations, aerodynamic uncertainties, center-of-gravity off-sets, and weight uncertainties. The impact of the perturbations on the spacecraft performance is investigated using Monte Carlo repetitive statistical techniques. During the Solid Rocket Motor (SRM) deorbit phase, a target flight path angle of -4.76 deg at entry interface (EI) offers very high probability of avoiding SRM casing skip-out from the atmosphere. Generally speaking, the baseline designs of the guidance, navigation, and control systems satisfy most of the science and mission requirements.

  3. On the precision of aero-thermal simulations for TMT

    NASA Astrophysics Data System (ADS)

    Vogiatzis, Konstantinos; Thompson, Hugh

    2016-08-01

    Environmental effects on the Image Quality (IQ) of the Thirty Meter Telescope (TMT) are estimated by aero-thermal numerical simulations. These simulations utilize Computational Fluid Dynamics (CFD) to estimate, among others, thermal (dome and mirror) seeing as well as wind jitter and blur. As the design matures, guidance obtained from these numerical experiments can influence significant cost-performance trade-offs and even component survivability. The stochastic nature of environmental conditions results in the generation of a large computational solution matrix in order to statistically predict Observatory Performance. Moreover, the relative contribution of selected key subcomponents to IQ increases the parameter space and thus computational cost, while dictating a reduced prediction error bar. The current study presents the strategy followed to minimize prediction time and computational resources, the subsequent physical and numerical limitations and finally the approach to mitigate the issues experienced. In particular, the paper describes a mesh-independence study, the effect of interpolation of CFD results on the TMT IQ metric, and an analysis of the sensitivity of IQ to certain important heat sources and geometric features.

  4. Teaching Baroreflex Physiology to Medical Students: A Comparison of Quiz-Based and Conventional Teaching Strategies in a Laboratory Exercise

    ERIC Educational Resources Information Center

    Berg, Ronan M. G.; Plovsing, Ronni R.; Damgaard, Morten

    2012-01-01

    Quiz-based and collaborative teaching strategies have previously been found to be efficient for the improving meaningful learning of physiology during lectures. These approaches have, however, not been investigated during laboratory exercises. In the present study, we compared the impact of solving quizzes individually and in groups with…

  5. Fault Diagnosis of Demountable Disk-Drum Aero-Engine Rotor Using Customized Multiwavelet Method

    PubMed Central

    Chen, Jinglong; Wang, Yu; He, Zhengjia; Wang, Xiaodong

    2015-01-01

    The demountable disk-drum aero-engine rotor is an important piece of equipment that greatly impacts the safe operation of aircraft. However, assembly looseness or crack fault has led to several unscheduled breakdowns and serious accidents. Thus, condition monitoring and fault diagnosis technique are required for identifying abnormal conditions. Customized ensemble multiwavelet method for aero-engine rotor condition identification, using measured vibration data, is developed in this paper. First, customized multiwavelet basis function with strong adaptivity is constructed via symmetric multiwavelet lifting scheme. Then vibration signal is processed by customized ensemble multiwavelet transform. Next, normalized information entropy of multiwavelet decomposition coefficients is computed to directly reflect and evaluate the condition. The proposed approach is first applied to fault detection of an experimental aero-engine rotor. Finally, the proposed approach is used in an engineering application, where it successfully identified the crack fault of a demountable disk-drum aero-engine rotor. The results show that the proposed method possesses excellent performance in fault detection of aero-engine rotor. Moreover, the robustness of the multiwavelet method against noise is also tested and verified by simulation and field experiments. PMID:26512668

  6. Aero-Thermal Calibration of the NASA Glenn Icing Research Tunnel (2012 Test)

    NASA Technical Reports Server (NTRS)

    Pastor-Barsi, Christine M.; Arrington, E. Allen; VanZante, Judith Foss

    2012-01-01

    A major modification of the refrigeration plant and heat exchanger at the NASA Glenn Icing Research Tunnel (IRT) occurred in autumn of 2011. It is standard practice at NASA Glenn to perform a full aero-thermal calibration of the test section of a wind tunnel facility upon completion of major modifications. This paper will discuss the tools and techniques used to complete an aero-thermal calibration of the IRT and the results that were acquired. The goal of this test entry was to complete a flow quality survey and aero-thermal calibration measurements in the test section of the IRT. Test hardware that was used includes the 2D Resistive Temperature Detector (RTD) array, 9-ft pressure survey rake, hot wire survey rake, and the quick check survey rake. This test hardware provides a map of the velocity, Mach number, total and static pressure, total temperature, flow angle and turbulence intensity. The data acquired were then reduced to examine pressure, temperature, velocity, flow angle, and turbulence intensity. Reduced data has been evaluated to assess how the facility meets flow quality goals. No icing conditions were tested as part of the aero-thermal calibration. However, the effects of the spray bar air injections on the flow quality and aero-thermal calibration measurements were examined as part of this calibration.

  7. Fault Diagnosis of Demountable Disk-Drum Aero-Engine Rotor Using Customized Multiwavelet Method.

    PubMed

    Chen, Jinglong; Wang, Yu; He, Zhengjia; Wang, Xiaodong

    2015-10-23

    The demountable disk-drum aero-engine rotor is an important piece of equipment that greatly impacts the safe operation of aircraft. However, assembly looseness or crack fault has led to several unscheduled breakdowns and serious accidents. Thus, condition monitoring and fault diagnosis technique are required for identifying abnormal conditions. Customized ensemble multiwavelet method for aero-engine rotor condition identification, using measured vibration data, is developed in this paper. First, customized multiwavelet basis function with strong adaptivity is constructed via symmetric multiwavelet lifting scheme. Then vibration signal is processed by customized ensemble multiwavelet transform. Next, normalized information entropy of multiwavelet decomposition coefficients is computed to directly reflect and evaluate the condition. The proposed approach is first applied to fault detection of an experimental aero-engine rotor. Finally, the proposed approach is used in an engineering application, where it successfully identified the crack fault of a demountable disk-drum aero-engine rotor. The results show that the proposed method possesses excellent performance in fault detection of aero-engine rotor. Moreover, the robustness of the multiwavelet method against noise is also tested and verified by simulation and field experiments.

  8. A simulated hospital pharmacy module using an electronic medical record in a pharmaceutical care skills laboratory course.

    PubMed

    Kirwin, Jennifer L; DiVall, Margarita V; Guerra, Christina; Brown, Todd

    2013-04-12

    OBJECTIVES. To implement and evaluate the effects of a simulated hospital pharmacy module using an electronic medical record on student confidence and abilities to perform hospital pharmacist duties. DESIGN. A module was developed that simulated typical hospital pharmacist tasks. Learning activities were modified based upon student feedback and instructor assessment. ASSESSMENTS. Ninety-seven percent of respondents reported full-time hospital internship experience and 72% had electronic medical record experience prior to completing the module. Mean scores on confidence with performing typical hospital pharmacist tasks significantly increased from the pre-module survey to the post-module survey from 1.5-2.9 (low comfort/confidence) to 2.0-3.4 (moderate comfort/confidence). Course assessments confirmed student achievement of covered competencies. CONCLUSIONS. A simulated hospital pharmacy module improved pharmacy students' hospital practice skills and their perceived comfort and confidence in completing the typical duties of a hospital pharmacist.

  9. Impact of the GPA and Prior College Experience on the Completion of the Navy Medical Laboratory Technician Program

    DTIC Science & Technology

    2005-12-01

    was conducted in the am or pm. The senior phase clinical rotation included clinical reinforcement for: Microbiology, Parasitology, Immunology , Blood...sciences. Major disciplines of the clinical laboratory include; clinical chemistry, urinalysis, hematology, immunology , blood bank and microbiology...Microbiology, Parasitology, Immunology , Blood Bank and Donor Center. The hours of rotation were from 6:30 am - 3:30 pm for 64 days x 8 hours/day = 512 hours

  10. Seroprevalence of anti-Toxoplasma IgG and IgM among individuals who were referred to medical laboratories in Mazandaran province, northern Iran.

    PubMed

    Sharif, Mehdi; Daryani, Ahmad; Ebrahimnejad, Zahra; Gholami, Shirzad; Ahmadpour, Ehsan; Borhani, Samaneh; Lamsechi, Narges

    2016-01-01

    Toxoplasma gondii (T. gondii) is a protozoan parasite that can cause toxoplasmosis in humans. However, there is no current data regarding Toxoplasma infection among individuals who were referred to medical laboratories in Mazandaran province (northern Iran). Therefore, we performed a population-based study of Toxoplasma seroprevalence in this region. A total of 1832 sera samples (from 654 men and 1178 women) were collected from people who were referred to medical laboratories in different cities throughout Mazandaran province between March and July 2012. The serum titers of anti-T. gondii IgG and IgM were measured using enzyme-linked immunosorbent assays. The seroprevalence of anti-Toxoplasma IgG was 55.5%; and 14.4% of the positive samples were seropositive for anti-Toxoplasma IgM. The highest seroprevalence was observed among people who were >50 years old (90.6%), and the lowest seroprevalence was observed among children who were 0-9 years old (9.4%; P<0.001). There was no significant difference in the seroprevalences for each sex in the study population. However, a regional sex-specific difference in seroprevalence was observed between men (54.1%) and women (70.6%; P=0.003) in the western cities of Mazandaran. As the seroprevalence of T. gondii in western and eastern Mazandaran was higher than that in the central cities, there is a need to evaluate the nature of the infection chain in these areas.

  11. The relationship of patient medical and laboratory characteristics to changes in functional health status in children and adolescents after the Fontan procedure.

    PubMed

    McCrindle, Brian W; Zak, Victor; Breitbart, Roger E; Mahony, Lynn; Shrader, Peter; Lai, Wyman W; Burns, Kristin M; Colan, Steven D; Williams, Richard V; Goldberg, David; Hill, Kevin D; Khaikin, Svetlana; Atz, Andrew M

    2014-04-01

    Despite hypothesized concerns about deterioration beginning in adolescence, longitudinal data and associated factors regarding standardized assessment of physical functioning are not available for Fontan patients. Parents who participated in the Fontan Cross-Sectional Study completed the Child Health Questionnaire at 2 time points for 245 subjects ages 6-18 years. Associations between change in Physical Functioning Summary Score and baseline patient, medical, and laboratory characteristics (mean age 9.5 ± 1.7 years) and follow-up patient and medical characteristics (mean age 16.2 ± 1.6 years) were determined by regression analyses. During a mean of 6.7 ± 0.4 years, a small (not clinically important) but statistically significant decrease in score from 46.2 ± 11.7 to 44.5 ± 12.1 (p < 0.03) was noted. Subjects with higher baseline scores had a greater decrease in score (r = -0.48; p < 0.001). A multivariable model of patient and medical characteristics (R(2) = 0.11) showed that a greater decrease in score was significantly associated with interim development of asthma (n = 13; parameter estimate [PE] -6.6; p < 0.05) or other chronic respiratory, lung, or breathing problems (n = 13; PE -12.5; p < 0.001) and the presence of protein-losing enteropathy at any time (n = 12; PE -9.4; p = 0.006). Change in score was not significantly associated with baseline laboratory measures of exercise capacity and ventricular characteristics and function. Therefore, although physical functioning may be stable during adolescence for many Fontan patients, deterioration occurs in some in association with respiratory conditions and protein-losing enteropathy. Further longitudinal study is necessary to better understand the relationship between clinical morbidities and functional health status as these patients transition into adulthood.

  12. The Relationship of Patient, Medical and Laboratory Characteristics to Changes in Functional Health Status in Children and Adolescents After the Fontan Procedure

    PubMed Central

    McCrindle, Brian W.; Zak, Victor; Breitbart, Roger E.; Mahony, Lynn; Shrader, Peter; Lai, Wyman W.; Burns, Kristin M.; Colan, Steven D.; Williams, Richard V.; Goldberg, David; Hill, Kevin D.; Khaikin, Svetlana; Atz, Andrew M.

    2014-01-01

    Despite hypothesized concerns about deterioration beginning in adolescence, longitudinal data and associated factors regarding standardized assessment of physical functioning are not available for Fontan patients. Parents who participated in the Fontan Cross-Sectional Study completed the Child Health Questionnaire at two time points for 245 subjects ages 6 to 18 years. Associations between change in Physical Functioning Summary Score and baseline patient, medical and laboratory characteristics (mean age 9.5±1.7 years) and follow-up patient and medical characteristics (mean age 16.2±1.6 years) were determined by regression analyses. Over a mean of 6.7±0.4 years, a small (not clinically important) but statistically significant decline in score from 46.2±11.7 to 44.5±12.1 (p<0.03) was noted. Subjects with higher baseline scores had a greater decline in score (r=−0.48; p<0.001). A multivariable model of patient and medical characteristics (R2=0.11) showed that a greater decline in score was significantly associated with interim development of asthma (n=13; parameter estimate [PE] −6.6; p<0.05) or other chronic respiratory, lung or breathing problems (n=13; PE −12.5; p<0.001), and the presence of protein-losing enteropathy at any time (n=12; PE −9.4; p=0.006). Change in score was not significantly associated with baseline laboratory measures of exercise capacity and ventricular characteristics and function. Therefore, although physical functioning may be stable during adolescence for many Fontan patients, deterioration occurs in some in association with respiratory conditions and protein-losing enteropathy. Further longitudinal study is necessary to better understand the relationship between clinical morbidities and functional health status as these patients transition into adulthood. PMID:24264999

  13. Aero-thermal analysis of lifting body configurations in hypersonic flow

    NASA Astrophysics Data System (ADS)

    Kumar, Sachin; Mahulikar, Shripad P.

    2016-09-01

    The aero-thermal analysis of a hypersonic vehicle is of fundamental interest for designing its thermal protection system. The aero-thermal environment predictions over several critical regions of the hypothesized lifting body vehicle, including the stagnation region of the nose-cap, cylindrically swept leading edges, fuselage-upper, and fuselage-lower surfaces, are discussed. The drag (Λ=70°) and temperature (Λ=80°) minimized sweepback angles are considered in the configuration design of the two hypothesized lifting body shape hypersonic vehicles. The main aim of the present study is to analyze and compare the aero-thermal characteristics of these two lifting body configurations at same heat capacity. Accordingly, a Computational Fluid Dynamics simulation has been carried out at Mach number (M∞=7), H=35 km altitude with zero Angle of Attack. Finally, the material selection for thermal protection system based on these predictions and current methodology is described.

  14. SFC Optimization for Aero Engine Based on Hybrid GA-SQP Method

    NASA Astrophysics Data System (ADS)

    Li, Jie; Fan, Ding; Sreeram, Victor

    2013-12-01

    This study focuses on on-line specific fuel consumption (SFC) optimization of aero engines. For solving this optimization problem, a nonlinear pneumatic and thermodynamics model of the aero engine is built and a hybrid optimization technique which is formed by combining the genetic algorithm (GA) and the sequential quadratic programming (SQP) is presented. The ability of standard GA and standard SQP in solving this type of problem is investigated. It has been found that, although the SQP is fast, very little SFC reductions can be obtained. The GA is able to solve the problem well but a lot of computational time is needed. The presented hybrid GA-SQP gives a good SFC optimization effect and saves 76.6% computational time when compared to the standard GA. It has been shown that the hybrid GA-SQP is a more effective and higher real-time method for SFC on-line optimization of the aero engine.

  15. High-Temperature Adhesives for Thermally Stable Aero-Assist Technologies

    NASA Technical Reports Server (NTRS)

    Eberts, Kenneth; Ou, Runqing

    2013-01-01

    Aero-assist technologies are used to control the velocity of exploration vehicles (EVs) when entering Earth or other planetary atmospheres. Since entry of EVs in planetary atmospheres results in significant heating, thermally stable aero-assist technologies are required to avoid the high heating rates while maintaining low mass. Polymer adhesives are used in aero-assist structures because of the need for high flexibility and good bonding between layers of polymer films or fabrics. However, current polymer adhesives cannot withstand temperatures above 400 C. This innovation utilizes nanotechnology capabilities to address this need, leading to the development of high-temperature adhesives that exhibit high thermal conductivity in addition to increased thermal decomposition temperature. Enhanced thermal conductivity will help to dissipate heat quickly and effectively to avoid temperature rising to harmful levels. This, together with increased thermal decomposition temperature, will enable the adhesives to sustain transient high-temperature conditions.

  16. AeroMACS C-Band Interference Modeling and Simulation Results

    NASA Technical Reports Server (NTRS)

    Wilson, Jeffrey

    2010-01-01

    A new C-band (5091-5150 MHz) airport communications system designated as Aeronautical Mobile Airport Communications System (AeroMACS) is being planned under the Federal Aviation Administration s NextGen program. It is necessary to establish practical limits on AeroMACS transmission power from airports so that the threshold of interference into the Mobile Satellite Service (Globalstar) feeder uplinks is not exceeded. To help provide guidelines for these limits, interference models have been created with the commercial software Visualyse Professional. In this presentation, simulation results were shown for the aggregate interference power at low earth orbit from AeroMACS transmitters at each of up to 757 airports in the United States, Canada, Mexico, and the surrounding area. Both omni-directional and sectoral antenna configurations were modeled. Effects of antenna height, beamwidth, and tilt were presented.

  17. Frequency-domain Model Matching PID Controller Design for Aero-engine

    NASA Astrophysics Data System (ADS)

    Liu, Nan; Huang, Jinquan; Lu, Feng

    2014-12-01

    The nonlinear model of aero-engine was linearized at multiple operation points by using frequency response method. The validation results indicate high accuracy of static and dynamic characteristics of the linear models. The improved PID tuning method of frequency-domain model matching was proposed with the system stability condition considered. The proposed method was applied to the design of PID controller of the high pressure rotor speed control in the flight envelope, and the control effects were evaluated by the nonlinear model. Simulation results show that the system had quick dynamic response with zero overshoot and zero steadystate error. Furthermore, a PID-fuzzy switching control scheme for aero-engine was designed, and the fuzzy switching system stability was proved. Simulations were studied to validate the applicability of the multiple PIDs fuzzy switching controller for aero-engine with wide range dynamics.

  18. The response of medical virology laboratories to the influenza A(H1N1)pdm09 outbreak in Paris Île-de-France region.

    PubMed

    Seringe, E; Agut, H

    2013-10-01

    The outbreak of influenza A(H1N1)pdm09 was a challenge for the laboratories of Paris Île-de-France region in charge of virological diagnosis. In order to evaluate the quality of their response to this challenge, a retrospective survey based on a self-administered standardized questionnaire was undertaken among the 18 hospital laboratories involved in A(H1N1)pdm09 virus detection over a period of 10 months from April 2009 to January 2010. All concerned laboratories responded to the survey. Due to imposed initial biosafety constraints and indications, virological diagnosis was performed in only two laboratories at the start of the studied period. Step by step, it was further settled in the other laboratories starting from June to November 2009. From the beginning, A(H1N1)pdm09-specific RT-PCR was considered the reference method while the use of rapid influenza detection tests remained temporary and concerned a minority of these laboratories. Among the overall 21,656 specimens received, a positive diagnosis of influenza A(H1N1)pdm09 was obtained in 5,390 cases (25%), the positivity range being significantly higher among women as compared to men (P<0.0001) and subjects below 45 years of age as compared to those over 65 years (P<0.0001). Two peaks in positivity frequency were observed at weeks 24 (30%, 8-12 June 2009) and 44 (50%, 26-30 October 2009) respectively, the latter one occurring 2 weeks earlier than the peak of epidemic at the national level. In contrast, a low positivity rate was detected at weeks 38-40 in relationship with other respiratory virus infections which were clinically misinterpreted as a peak of influenza epidemic. These data demonstrate the ability of medical virology laboratories of Paris Île-de-France region to provide in real time a valuable diagnosis of A(H1N1)pdm09 virus infection and a relevant view of outbreak evolution, suggesting they will be a crucial component in the management of future influenza epidemics.

  19. The Facilitation of Problem-Based Learning in Medical Education Through a Computer-Mediated Tutorial Laboratory

    PubMed Central

    Myers, A.; Barrows, H.S.; Koschmann, T.D.; Feltovich, P.J.

    1990-01-01

    This paper describes the means by which a computer-supported group interaction system known as the Computer-Mediated Tutorial Laboratory (CMTL) is used to support Problem-Based Learning Tutorials. The Problem-Based Learning Tutorial process has traditionally been solely a group process, sharing both the advantages and the disadvantages of any group process. This paper discusses the nature of Problem-Based Learning, the logistics of integrating computer mediation with the tutorial process and how computer mediation can be used to facilitate the eliciting and recording of individual input while enhancing the powerful effects of the group process.

  20. On Proper Selection of Multihop Relays for Future Enhancement of AeroMACS Networks

    NASA Technical Reports Server (NTRS)

    Kamali, Behnam; Kerczewski, Robert J.; Apaza, Rafael D.

    2015-01-01

    As the Aeronautical Mobile Airport Communications System (AeroMACS) has evolved from a technology concept to a deployed communications network over major US airports, it is now time to contemplate whether the existing capacity of AeroMACS is sufficient to meet the demands set forth by all fixed and mobile applications over the airport surface given the AeroMACS constraints regarding bandwidth and transmit power. The underlying idea in this article is to present IEEE 802.16j-based WiMAX as a technology that can address future capacity enhancements and therefore is most feasible for AeroMACS applications. The principal argument in favor IEEE 802.16j technology is the flexible and cost effective extension of radio coverage that is afforded by relay fortified networks, with virtually no increase in the power requirements and virtually no rise in interference levels to co-allocated applications. The IEEE 802.16j-based multihop relay systems are briefly described. The focus is on key features of this technology, frame structure, and its architecture. Next, AeroMACS is described as a WiMAX-based wireless network. The two major relay modes supported by IEEE 802.16j amendment, i.e., transparent and non-transparent are described. The benefits of employing multihop relays are listed. Some key challenges related to incorporating relays into AeroMACS networks are discussed. The selection of relay type in a broadband wireless network affects a number of network parameters such as latency, signal overhead, PHY (Scalable Physical Layer) and MAC (Media Access Layer) layer protocols, consequently it can alter key network quantities of throughput and QoS (Quality of Service).

  1. Laboratory and clinical data on wound healing by low-power laser from the Medical Institute of Vilafortuny, Spain

    NASA Astrophysics Data System (ADS)

    Trelles, Mario A.; Mayayo, E.; Resa, A. M.; Rigau, Josepa; Calvo, G.

    1991-05-01

    Low power laser has been claimed, both at laboratory and for clinical treatment to activate wound healing. Chronic ulcers respond very positively to laser treatment when particular rules of irradiation are take into account. The multiple etiology of chronic ulcers is not conductive to treatment selection, including laser treatment, if the associated illness is not taken into consideration. For more than 14 years our clinical experience have been significantly positive using lasers in the treatment of chronic ulcers. Our causistic, based on 242 cases treated from 1975 through 1983, has kept in many cases very close follow-up for an extended time periods of up to six years after healing. By controlling photographically and microscopically a chronic venous ulcer submitted to low density laser irradiation, as well as by studying the process of reparation of experimental ulcers and burns, produce on laboratory animal, the healing effects of laser radiation can be followed. Statistically, it is possible to estimate that low intensity laser irradiation produces faster reparation of damage tissue.

  2. Aero-Thermal Calibration of the NASA Glenn Icing Research Tunnel (2004 and 2005 Tests)

    NASA Technical Reports Server (NTRS)

    Arrington, E. Allen; Pastor, Christine M.; Gonsalez, Jose C.; Curry, Monroe R., III

    2010-01-01

    A full aero-thermal calibration of the NASA Glenn Icing Research Tunnel was completed in 2004 following the replacement of the inlet guide vanes upstream of the tunnel drive system and improvement to the facility total temperature instrumentation. This calibration test provided data used to fully document the aero-thermal flow quality in the IRT test section and to construct calibration curves for the operation of the IRT. The 2004 test was also the first to use the 2-D RTD array, an improved total temperature calibration measurement platform.

  3. Establishing cytogenetic biodosimetry laboratory in Saudi Arabia and producing preliminary calibration curve of dicentric chromosomes as biomarker for medical dose estimation in response to radiation emergencies.

    PubMed

    Al-Hadyan, Khaled; Elewisy, Sara; Moftah, Belal; Shoukri, Mohamed; Alzahrany, Awad; Alsbeih, Ghazi

    2014-12-01

    In cases of public or occupational radiation overexposure and eventual radiological accidents, it is important to provide dose assessment, medical triage, diagnoses and treatment to victims. Cytogenetic bio-dosimetry based on scoring of dicentric chromosomal aberrations assay (DCA) is the "gold standard" biotechnology technique for estimating medically relevant radiation doses. Under the auspices of the National Science, Technology and Innovation Plan in Saudi Arabia, we have set up a biodosimetry laboratory and produced a national standard dose-response calibration curve for DCA, pre-required to estimate the doses received. For this, the basic cytogenetic DCA technique needed to be established. Peripheral blood lymphocytes were collected from four healthy volunteers and irradiated with radiation doses between 0 and 5 Gy of 320 keV X-rays. Then, lymphocytes were PHA stimulated, Colcemid division arrested and stained cytogenetic slides were prepared. The Metafer4 system (MetaSystem) was used for automatic and manually assisted metaphase finding and scoring of dicentric chromosomes. Results were fit to the linear-quadratic dose-effect model according to the IAEA EPR-Biodosimetry-2011 report. The resulting manually assisted dose-response calibration curve (Y = 0.0017 + 0.026 × D + 0.081 × D(2)) was in the range of those described in other populations. Although the automated scoring over-and-under estimates DCA at low (<1 Gy) and high (>2 Gy) doses, respectively, it showed potential for use in triage mode to segregate between victims with potential risk to develop acute radiotoxicity syndromes. In conclusion, we have successfully established the first biodosimetry laboratory in the region and have produced a preliminary national dose-response calibration curve. The laboratory can now contribute to the national preparedness plan in response to eventual radiation emergencies in addition to providing information for decision makers and public health

  4. [Onychomycosis in Morocco: experience of the parasitology and medical mycology laboratory from Rabat children hospital (1982-2003)].

    PubMed

    Boukachabine, K; Agoumi, A

    2005-01-01

    Cases of onychomycosis diagnosed by mycological examination in the parasitology and mycology laboratory (Children Hospital, Rabat, Marocco) over the 22-year period, between 1982 and 2003, have been reviewed. 17,177 dermatophytes have been isolated in 4,940 patients. Dermatophytes presented 61.46% of onychomycosis, yeasts Candida albicans were responsible in 25.5%, moulds in 1.53% and for 12% fungi identification was not determined (positive direct examination or negative direct examination and culture despite typical clinical aspect). The most frequent dermatophyte was Trichophyton rubrum (83.6%), followed by Trichophyton violaceum var. glabrum (9%) and Trichophyton mentagrophytes var. interdigitale (6.9%). Candida albicans was the prevalent yeast. Moulds were mainly Fusarium spp. (47%), followed Scopulariopsis brevicaulis (16%) and Aspergillus spp. (12%). Dermatophytes and moulds most commonly infected the toenails, yeasts the fingernails.

  5. The Role of Medical Imaging in the Recharacterization of Mild Traumatic Brain Injury Using Youth Sports as a Laboratory

    PubMed Central

    Talavage, Thomas M.; Nauman, Eric A.; Leverenz, Larry J.

    2016-01-01

    The short- and long-term impact of mild traumatic brain injury (TBI) is an increasingly vital concern for both military and civilian personnel. Such injuries produce significant social and financial burdens and necessitate improved diagnostic and treatment methods. Recent integration of neuroimaging and biomechanical studies in youth collision-sport athletes has revealed that significant alterations in brain structure and function occur even in the absence of traditional clinical markers of “concussion.” While task performance is maintained, athletes exposed to repetitive head accelerations exhibit structural changes to the underlying white matter, altered glial cell metabolism, aberrant vascular response, and marked changes in functional network behavior. Moreover, these changes accumulate with accrued years of exposure, suggesting a cumulative trauma mechanism that may culminate in categorization as “concussion” and long-term neurological deficits. The goal of this review is to elucidate the role of medical imaging in recharacterizing TBI, as a whole, to better identify at-risk individuals and improve the development of preventative and interventional approaches. PMID:26834695

  6. Determination of vitamin A (retinol) in infant and medical nutritional formulas with AOAC method 992.06 using a modified extraction procedure: single-laboratory validation.

    PubMed

    Thompson, Linda B; Schimpf, Karen J; Stiner, Lisa A; Schmitz, Daniel J

    2010-01-01

    The applicability of AOAC Official Method 992.06, vitamin A (retinol) in milk-based infant formula can be extended to specialty infant formulas, and medical and adult nutritional products with a few minor modifications to the sample preparation procedure. Currently, AOAC Official Method 992.06 is only applicable to milk-based infant formulas containing >500 IU vitamin A per reconstituted quart. When this method is used as written to test specialty infant formulas, vitamin A recoveries are low compared to results generated with alternate validated vitamin A methods. AOAC Method 992.06 vitamin A recoveries can be improved significantly in specialty infant formulas if the amount of potassium hydroxide used during the saponification step is doubled. With this one minor modification to the sample preparation procedure, AOAC Method 992.06 demonstrates acceptable precision and accuracy for the quantitation of vitamin A (retinol) in specialty infant formulas, milk- and soy-based infant formulas, and adult and medical nutritionals. Because increasing the amount of potassium hydroxide can cause emulsions to form, 2-4 mL aliquots of reagent alcohol may need to be added to some samples to separate the organic and aqueous layers during the extraction step. A single-laboratory validation of these modifications was completed. During validation, 15 different product matrixes were analyzed. The intermediate precision averaged 2.70% RSD, and spike recovery data averaged 96.3%.

  7. Response to the great East Japan earthquake of 2011 and the Fukushima nuclear crisis: the case of the Laboratory Animal Research Center at Fukushima Medical University.

    PubMed

    Katahira, Kiyoaki; Sekiguchi, Miho

    2013-01-01

    A magnitude 9.0 great earthquake, the 2011 off the Pacific coast of Tohoku Earthquake, occurred on March 11, 2011, and subsequent Fukushima Daiichi Nuclear Power Station (Fukushima NPS) accidents stirred up natural radiation around the campus of Fukushima Medical University (FMU). FMU is located in Fukushima City, and is 57 km to the northwest of Fukushima NPS. Due to temporary failure of the steam boilers, the air conditioning system for the animal rooms, all autoclaves, and a cage washer could not be used at the Laboratory Animal Research Center (LARC) of FMU. The outside air temperature dropped to zero overnight, and the temperature inside the animal rooms fell to 10°C for several hours. We placed sterilized nesting materials inside all cages to encourage rodents to create nests. The main water supply was cut off for 8 days in all, while supply of steam and hot water remained unavailable for 12 days. It took 20 days to restore the air conditioning system to normal operation at the facility. We measured radiation levels in the animal rooms to confirm the safety of care staff and researchers. On April 21, May 9, and June 17, the average radiation levels at a central work table in the animal rooms with HEPA filters were 46.5, 44.4, and 43.4 cpm, respectively, which is equal to the background level of the equipment. We sincerely hope our experiences will be a useful reference regarding crisis management for many institutes having laboratory animals.

  8. 77 FR 30371 - Airworthiness Directives; International Aero Engines AG Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... Engines AG Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are superseding an existing airworthiness directive (AD) for all International Aero Engines AG (IAE) V2500-A1, V2525-D5 and V2528-D5 turbofan engines, and certain serial numbers (S/Ns) of IAE...

  9. 78 FR 22168 - Airworthiness Directives; International Aero Engines AG Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... Engines AG Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain International Aero Engines AG (IAE), V2525-D5 and V2528-D5 turbofan engines, with a certain No. 4 bearing internal scavenge tube and...

  10. Dependence of AeroMACS Interference on Airport Radiation Pattern Characteristics

    NASA Technical Reports Server (NTRS)

    Wilson, Jeffrey D.

    2012-01-01

    AeroMACS (Aeronautical Mobile Airport Communications System), which is based upon the IEEE 802.16e mobile wireless standard, is expected to be implemented in the 5091 to 5150 MHz frequency band. As this band is also occupied by Mobile Satellite Service (MSS) feeder uplinks, AeroMACS must be designed to avoid interference with this incumbent service. The aspects of AeroMACS operation that present potential interference are under analysis in order to enable the definition of standards that assure that such interference will be avoided. In this study, the cumulative interference power distribution at low earth orbit from AeroMACS transmitters at the 497 major airports in the contiguous United States was simulated with the Visualyse Professional software. The dependence of the interference power on the number of antenna beams per airport, gain patterns, and beam direction orientations was simulated. As a function of these parameters, the simulation results are presented in terms of the limitations on transmitter power required to maintain the cumulative interference power under the established threshold.

  11. 78 FR 69600 - Airworthiness Directives; Piaggio Aero Industries S.p.A Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... Industries S.p.A Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT... (AD) for certain Piaggio Aero Industries S.p.A. Model P-180 airplanes. This proposed AD results from... p.m., Monday through Friday, except Federal holidays. For service information identified in...

  12. 75 FR 5690 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A. Model P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... INDUSTRIES S.p.A. Model P- 180 Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. The AD docket contains the NPRM...: 2010-03-04 PIAGGIO AERO INDUSTRIES S.p.A.: Amendment 39-16187; Docket No. FAA-2009-1081;...

  13. 76 FR 27872 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... INDUSTRIES S.p.A Model P- 180 Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ] ACTION: Final... known U.S. owners and operators of PIAGGIO AERO INDUSTRIES S.p.A (Piaggio) Model PIAGGIO P-180 airplanes... fuselage on a number of Piaggio Model P.180 aeroplanes, which resulted in jamming of the flight...

  14. Swept Blade Aero-Elastic Model for a Small Wind Turbine (Presentation)

    SciTech Connect

    Damiani, R.; Lee, S.; Larwood, S.

    2014-07-01

    A preprocessor for analyzing preswept wind turbines using the in-house aero-elastic tool coupled with a multibody dynamic simulator was developed. A baseline 10-kW small wind turbine with straight blades and various configurations that featured bend-torsion coupling via blade-tip sweep were investigated to study their impact on ultimate loads and fatigue damage equivalent loads.

  15. Application of Multihop Relay for Performance Enhancement of AeroMACS Networks

    NASA Technical Reports Server (NTRS)

    Kamali, Behnam; Wilson, Jeffrey D.; Kerczewski, Robert J.

    2012-01-01

    A new transmission technology, based on IEEE 802.16-2009 (WiMAX), is currently being developed for airport surface communications. A C-band spectrum allocation at 5091 to 5150 MHz has been created by International Telecommunications Union (ITU) to carry this application. The proposed technology, known as AeroMACS, will be used to support fixed and mobile ground to ground applications and services. This article proposes and demonstrates that IEEE 802.16j-amendment-based WiMAX is most feasible for AeroMACS applications. This amendment introduces multihop relay as an optional deployment that may be used to provide additional coverage and/or enhance the capacity of the network. Particular airport surface radio coverage situations for which IEEE 802.16-2009-WiMAX provides resolutions that are inefficient, costly, or excessively power consuming are discussed. In all these cases, it is argued that 16j technology offers a much better alternative. A major concern about deployment of AeroMACS is interference to co-allocated applications such as the Mobile Satellite Service (MSS) feeder link. Our initial simulation results suggest that no additional interference to MSS feeder link is caused by deployment of IEEE 802.16j-based AeroMACS.

  16. 78 FR 56589 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... INDUSTRIES S.p.A Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT... INDUSTRIES S.p.A Model P-180 airplanes. This AD results from mandatory continuing airworthiness information...., Washington, DC 20590. For service information identified in this AD, contact Piaggio Aero Industries...

  17. 78 FR 1776 - Airworthiness Directives; International Aero Engines AG Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Engines AG Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... Aero Engines AG (IAE), V2525-D5 and V2528-D5 turbofan engines, with a certain number (No.) 4 bearing... prompted by a report of an engine under-cowl fire and commanded in-flight shutdown. This proposed AD...

  18. 76 FR 82202 - Airworthiness Directives; International Aero Engines AG Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... Engines AG Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... International Aero Engines AG (IAE) V2500-A1, V2525-D5 and V2528-D5 turbofan engines, and certain serial numbers... engines. The existing AD currently requires initial and repetitive on-wing ultrasonic inspections...

  19. Common Aero Vehicle Autonomous Reentry Trajectory Optimization Satisfying Waypoint and No-Fly Zone Constraints

    DTIC Science & Technology

    2007-09-01

    used to converge to the optimal solution. This numerical approach is applied to the Common Aero Vehicle (CAV) as the test platform for the full three...6 EAGLE Evolved Acceleration Guidance Logic for Entry . . . . . . 10 POSTII Program To Optimize Simulated Trajectories II...11 LQR linear quadratic regulator . . . . . . . . . . . . . . . . . . 12 MILP Mixed- Integer Linear Programming

  20. OC3 -- Benchmark Exercise of Aero-Elastic Offshore Wind Turbine Codes: Preprint

    SciTech Connect

    Passon, P.; Kuhn, M.; Butterfield, S.; Jonkman, J.; Camp, T.; Larsen, T. J.

    2007-08-01

    This paper introduces the work content and status of the first international investigation and verification of aero-elastic codes for offshore wind turbines as performed by the "Offshore Code Comparison Collaboration" (OC3) within the "IEA Wind Annex XXIII -- Subtask 2".

  1. Computational methods to compute wavefront error due to aero-optic effects

    NASA Astrophysics Data System (ADS)

    Genberg, Victor; Michels, Gregory; Doyle, Keith; Bury, Mark; Sebastian, Thomas

    2013-09-01

    Aero-optic effects can have deleterious effects on high performance airborne optical sensors that must view through turbulent flow fields created by the aerodynamic effects of windows and domes. Evaluating aero-optic effects early in the program during the design stages allows mitigation strategies and optical system design trades to be performed to optimize system performance. This necessitates a computationally efficient means to evaluate the impact of aero-optic effects such that the resulting dynamic pointing errors and wavefront distortions due to the spatially and temporally varying flow field can be minimized or corrected. To this end, an aero-optic analysis capability was developed within the commercial software SigFit that couples CFD results with optical design tools. SigFit reads the CFD generated density profile using the CGNS file format. OPD maps are then created by converting the three-dimensional density field into an index of refraction field and then integrating along specified paths to compute OPD errors across the optical field. The OPD maps may be evaluated directly against system requirements or imported into commercial optical design software including Zemax® and Code V® for a more detailed assessment of the impact on optical performance from which design trades may be performed.

  2. 48 CFR 1852.235-70 - Center for AeroSpace Information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... avail itself of the services provided by the NASA Center for AeroSpace Information (CASI) (http://www.sti.nasa.gov) for the conduct of research or research and development required under this contract. CASI provides a variety of services and products as a NASA repository and database of...

  3. 48 CFR 1852.235-70 - Center for AeroSpace Information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... avail itself of the services provided by the NASA Center for AeroSpace Information (CASI) (http://www.sti.nasa.gov) for the conduct of research or research and development required under this contract. CASI provides a variety of services and products as a NASA repository and database of...

  4. AERO: A Decision Support Tool for Wind Erosion Assessment in Rangelands and Croplands

    NASA Astrophysics Data System (ADS)

    Galloza, M.; Webb, N.; Herrick, J.

    2015-12-01

    Wind erosion is a key driver of global land degradation, with on- and off-site impacts on agricultural production, air quality, ecosystem services and climate. Measuring rates of wind erosion and dust emission across land use and land cover types is important for quantifying the impacts and identifying and testing practical management options. This process can be assisted by the application of predictive models, which can be a powerful tool for land management agencies. The Aeolian EROsion (AERO) model, a wind erosion and dust emission model interface provides access by non-expert land managers to a sophisticated wind erosion decision-support tool. AERO incorporates land surface processes and sediment transport equations from existing wind erosion models and was designed for application with available national long-term monitoring datasets (e.g. USDI BLM Assessment, Inventory and Monitoring, USDA NRCS Natural Resources Inventory) and monitoring protocols. Ongoing AERO model calibration and validation are supported by geographically diverse data on wind erosion rates and land surface conditions collected by the new National Wind Erosion Research Network. Here we present the new AERO interface, describe parameterization of the underpinning wind erosion model, and provide a summary of the model applications across agricultural lands and rangelands in the United States.

  5. Dependence of AeroMACS Interference on Airport Radiation Pattern Characteristics

    NASA Technical Reports Server (NTRS)

    Wilson, Jeffrey D.

    2012-01-01

    AeroMACS (Aeronautical Mobile Airport Communications System), which is based upon the IEEE 802.16e mobile wireless standard, is expected to be implemented in the 5091-5150 MHz frequency band. As this band is also occupied by Mobile Satellite Service (MSS) feeder uplinks, AeroMACS must be designed to avoid interference with this incumbent service. The aspects of AeroMACS operation that present potential interference are under analysis in order to enable the definition of standards that assure that such interference will be avoided. In this study, the cumulative interference power distribution at low earth orbit from AeroMACS transmitters at the 497 major airports in the contiguous United States was simulated with the Visualyse Professional software. The dependence of the interference power on the number of antenna beams per airport, gain patterns, and beam direction orientations was simulated. As a function of these parameters, the simulation results are presented in terms of the limitations on transmitter power required to maintain the cumulative interference power under the established threshold.

  6. A Coupled-Adjoint Method for High-Fidelity Aero-Structural Optimization

    DTIC Science & Technology

    2002-10-01

    geometry engine, and an efficient gradient-based optimization algorithm. The aero-structural solver ensures accurate solutions by using high-fidelity...22 2.3.1 Geometry Engine and Database . . . . . . . . . . . . . . . . . . . . . 23 2.3.2 Displacement Transfer...86 5-6 Airfoil geometry at the root. . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 5-7 Airfoil geometry at mid semi-span

  7. Application of Multihop Relay for Performance Enhancement of AeroMACS Networks

    NASA Technical Reports Server (NTRS)

    Kamali, Behnam; Wilson, Jeffrey D.; Kerczewski, Robert J.

    2012-01-01

    A new transmission technology, based on IEEE 802.16-2009 (WiMAX), is currently being developed for airport surface communications. A C-band spectrum allocation at 5091-5150 MHz has been created by ITU to carry this application. The proposed technology, known as AeroMACS, will be used to support fixed and mobile ground to ground applications and services. This article proposes and demonstrates that IEEE 802.16j-amendment-based WiMAX is most feasible for AeroMACS applications. This amendment introduces multihop relay as an optional deployment that may be used to provide additional coverage and/or enhance the capacity of the network. Particular airport surface radio coverage situations for which IEEE 802.16-2009-WiMAX provides resolutions that are inefficient, costly, or excessively power consuming are discussed. In all these cases, it is argued that 16j technology offers a much better alternative. A major concern about deployment of AeroMACS is interference to co-allocated applications such as the Mobile Satellite Service (MSS) feeder link. Our initial simulation results suggest that no additional interference to MSS feeder link is caused by deployment of IEEE 802.16j-based AeroMACS.

  8. Simultaneous measurement of aero-optical distortion and turbulent structure in a heated boundary layer

    NASA Astrophysics Data System (ADS)

    Saxton-Fox, Theresa; McKeon, Beverley; Smith, Adam; Gordeyev, Stanislav

    2014-11-01

    This study examines the relationship between turbulent structures and the aero-optical distortion of a laser beam passing through a turbulent boundary layer. Previous studies by Smith et al. (AIAA, 2014--2491) have found a bulk convection velocity of 0 . 8U∞ for aero-optical distortion in turbulent boundary layers, motivating a comparison of the distortion with the outer boundary layer. In this study, a turbulent boundary layer is developed over a flat plate with a moderately-heated section of length 25 δ . Density variation in the thermal boundary layer leads to aero-optical distortion, which is measured with a Malley probe (Smith et al., AIAA, 2013--3133). Simultaneously, 2D PIV measurements are recorded in a wall-normal, streamwise plane centered on the Malley probe location. Experiments are run at Reθ = 2100 and at a Mach number of 0.03, with the heated wall 10 to 20°C above the free stream temperature. Correlations and conditional averages are carried out between Malley probe distortion angles and flow features in the PIV vector fields. Aero-optical distortion in this study will be compared to distortion in higher Mach number flows studied by Gordeyev et al. (J. Fluid Mech., 2014), with the aim of extending conclusions into compressible flows. This research is made possible by the Department of Defense through the National Defense & Engineering Graduate Fellowship (NDSEG) Program and by the Air Force Office of Scientific Research Grant # FA9550-12-1-0060.

  9. 77 FR 67764 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... Aero Industries S.p.A. Model P-180 airplanes. That AD currently requires replacement of any firewall... only affects those firewall shutoff valves referenced in the referenced service information. We are... determination of whether any firewall shutoff or crossfeed valve with a serial number in a certain range...

  10. The Association Between Use of a Clinical Decision Support Tool and Adherence to Monitoring for Medication-Laboratory Guidelines in the Ambulatory Setting

    PubMed Central

    Lau, B.; Overby, C. L.; Wirtz, H. S.; Devine, E. B.

    2013-01-01

    Summary Background Stage 2 Meaningful Use criteria require the use of clinical decision support systems (CDSS) on high priority health conditions to improve clinical quality measures. Although CDSS hold great promise, implementation has been fraught with challenges, evidence of their impact is mixed, and the optimal method of content delivery is unknown. Objective The authors investigated whether implementation of a simple clinical decision support (CDS) tool was associated with improved prescriber adherence to national medication-laboratory monitoring guidelines for safety (hepatic function, renal function, myalgias/rhabdomyolysis) and intermediate outcomes for antidiabetic (Hemoglobin A1c; HbA1c) and antihyperlipidemic (low density lipoprotein; LDL) medications prescribed within a diabetes registry. Methods This was a retrospective observational study conducted in three phases of CDS implementation (2008–2009): pre-, transition-, and post-Prescriptions evaluated were ordered from an electronic health record within a multispecialty medical group. Adherence was evaluated within and without applying guideline-imposed time constraints. Results Forty-thousand prescriptions were ordered over three timeframes. For hepatic and renal function, the proportion of prescriptions for which labs were monitored at any time increased from 52% to 65% (p<0.001); those that met time guidelines, from 14% to 21% (p<0.001). Only 6% of required labs were drawn to monitor for myalgias/rhabdomyolysis, regardless of timeframe. Over 90% of safety labs were within normal limits. The proportion of labs monitored at any time for LDL increased from 56% to 64% (p<0.001); those that met time guidelines from 11% to 17% (p<0.001). The proportion of labs monitored at any time for HbA1c remained the same (72%); those that met time guidelines decreased from 45% to 41% (p<0.001). Conclusion A simple CDS tool may be associated with improved adherence to guidelines. Efforts are needed to confirm

  11. Turret optimization using passive flow control to minimize aero-optic effects

    NASA Astrophysics Data System (ADS)

    Crahan, Grady C.

    Over the past several decades, optical systems have begun to be deployed regularly on aircraft that fly at compressible flow speeds. During this time, these optical systems have also moved towards shorter operating wavelengths that can deliver a higher peak irradiance in the focused spot on a distant target, and the assumption is that future systems will use even shorter-wavelength lasers. As this trend towards short-wavelength systems continues, the need to take into account the effect of flow-induced, or "aero-optic," aberrations that occur in the vicinity of the parent aircraft has become progressively more important. The conventional method for mounting an optical system is to place it in a hemispherical turret; however, from an aero-optic standpoint, there are two problems with this mounting arrangement. First, shocks begin to form on the surface of a sphere (or hemisphere) at a critical Mach number of only around 0.55. Furthermore, a shear layer is produced due to flow separation on the aft side of the sphere; both of these flows, shocks and separated shear layers, involve strong index-of-refraction variations in the flow that would severely aberrate the outgoing beam. One approach to the problem would be to employ adaptive-optic (AO) methods in which the conjugate of the aberration is applied to the outgoing beam before it transmits through the aero-optic flow; however, state-of-the-art AO systems are generally unable to match the high temporal frequencies associated with aero-optic flows. As such, there is a need for innovative mounting strategies for optical systems that avoid or mitigate the formation of optically-aberrating flows in the first place. This dissertation outlines an investigation into aerodynamic shaping of turrets to mitigate the aero-optic aberrations produced by shock waves and shear layers. Specifically, a computational and experimental investigation into the "virtual duct" concept, which is a passive flow-control approach to mitigating

  12. Analysis of vitamin D status at two academic medical centers and a national reference laboratory: result patterns vary by age, gender, season, and patient location

    PubMed Central

    2013-01-01

    Background Testing for 25-hydroxyvitamin D [25(OH)D] has increased dramatically in recent years. The present report compares overall utilization and results for 25(OH)D orders at two academic medical centers - one in New York and one in Iowa – in order to characterize the vitamin D status of our inpatient and outpatient populations. Results are also compared to those from a national reference laboratory to determine whether patterns at these two institutions reflect those observed nationally. Methods Retrospective data queries of 25(OH)D orders and results were conducted using the laboratory information systems at Weill Cornell Medical College / New York Presbyterian Hospital (WCMC), University of Iowa Hospitals and Clinics (UIHC), and ARUP Laboratories (ARUP). Chart review was conducted for cases with very high or low serum 25(OH)D levels in the WCMC and UIHC datasets. Results The majority of tests were ordered on females and outpatients. Average serum 25(OH)D levels were higher in female versus male patients across most ages in the WCMC, UIHC, and ARUP datasets. As expected, average serum 25(OH)D levels were higher in outpatients than inpatients. Serum 25(OH)D levels showed seasonal periodicity, with average levels higher in summer than winter and correlating to regional UV index. Area plots demonstrated a peak of increased 25(OH)D insufficiency / deficiency in adolescent females, although overall worse 25(OH)D status was found in male versus female patients in the WCMC, UIHC, and ARUP datasets. Surprisingly, improved 25(OH)D status was observed in patients starting near age 50. Finally, chart review of WCMC and UIHC datasets revealed over-supplementation (especially of ≥ 50,000 IU weekly doses) in the rare cases of very high 25(OH)D levels. General nutritional deficiency and/or severe illness was found in most cases of severe 25(OH)D deficiency. Conclusions 25(OH)D status of patients seen by healthcare providers varies according to age, gender, season

  13. AeroStat: NASA Giovanni Tool for Statistical Intercomparison of Aerosols

    NASA Astrophysics Data System (ADS)

    Wei, J. C.; Petrenko, M.; Leptoukh, G. G.; Lynnes, C.; Da Silva, D.; Hegde, M.; Ichoku, C. M.

    2011-12-01

    Giovanni is a NASA's interactive online visualization and analysis tool for exploring very large global Earth science datasets. One of the new Giovanni analytical and statistical tools is called AeroStat, and it is designed to perform the direct statistical intercomparison of global aerosol parameters. Currently, we incorporate the MAPSS (A Multi-sensor Aerosol Products Sampling System) data that provides spatio-temporal statistics for multiple spatial spaceborne Level 2 aerosol products (MODIS Terra, MODIS Aqua, MISR, POLDER, OMI and CALIOP) sampled over AERONET ground stations. The dataset period, 1997-2011 (up to date), is long enough to encompass a number of scientifically challenging cases of long-term global aerosol validation from multi-sensors. AeroStat allows users to easily visualize and analyze in details the statistical properties of such cases, including data collected from multiple sensors and quality assurance (QA) properties of these data. One of the goals of AeroStat is to also provide a collaborative research environment, where aerosol scientists can share pertinent research workflow information, including data cases of interest, algorithms, best practices, and known errors, with the broader science community and enable other users of the system to easily reproduce and independently verify their results. Furthermore, AeroStat provides an easy access to the data provenance (data lineage) and quality information, which allows for a convenient tracing of scientific results back to their original input data, thus further ensuring the reliability of these results. Case studies will be presented to show the described functionality and capabilities of AeroStat, and possible directions of the future development.

  14. Understanding Aero-Fractures using optics and acoustics

    NASA Astrophysics Data System (ADS)

    Turkaya, Semih; Toussaint, Renaud; Kvalheim Eriksen, Fredrik; Zecevic, Megan; Daniel, Guillaume; Grude Flekkøy, Eirik; Jørgen Måløy, Knut

    2016-04-01

    exponent p value around 0.5. An analytical model of overpressure diffusion predicting p = 0.5 and two other free parameters of the Omori Law (prefactor and origin time) is developed. The spatial density of the seismic events, and the time of end of formation of the channels can also be predicted using this developed model. Using direct simulations of acoustic emissions due to the air vibration in opening fractal cavities, the evolution in the power spectrum is investigated. 1. Turkaya S, Toussaint R, Eriksen FK, Zecevic M, Daniel G, Flekkøy EG, Måløy KJ. "Bridging aero-fracture evolution with the characteristics of the acoustic emissions in a porous medium." Front. Phys.3:70. 2015 doi: 10.3389/fphy.2015.00070

  15. A Mission Concept: Re-Entry Hopper-Aero-Space-Craft System on-Mars (REARM-Mars)

    NASA Technical Reports Server (NTRS)

    Davoodi, Faranak

    2013-01-01

    Future missions to Mars that would need a sophisticated lander, hopper, or rover could benefit from the REARM Architecture. The mission concept REARM Architecture is designed to provide unprecedented capabilities for future Mars exploration missions, including human exploration and possible sample-return missions, as a reusable lander, ascend/descend vehicle, refuelable hopper, multiple-location sample-return collector, laboratory, and a cargo system for assets and humans. These could all be possible by adding just a single customized Re-Entry-Hopper-Aero-Space-Craft System, called REARM-spacecraft, and a docking station at the Martian orbit, called REARM-dock. REARM could dramatically decrease the time and the expense required to launch new exploratory missions on Mars by making them less dependent on Earth and by reusing the assets already designed, built, and sent to Mars. REARM would introduce a new class of Mars exploration missions, which could explore much larger expanses of Mars in a much faster fashion and with much more sophisticated lab instruments. The proposed REARM architecture consists of the following subsystems: REARM-dock, REARM-spacecraft, sky-crane, secure-attached-compartment, sample-return container, agile rover, scalable orbital lab, and on-the-road robotic handymen.

  16. High-Throughput Identification of Bacteria and Yeast by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Conventional Medical Microbiology Laboratories

    PubMed Central

    van Veen, S. Q.; Claas, E. C. J.; Kuijper, Ed J.

    2010-01-01

    Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is suitable for high-throughput and rapid diagnostics at low costs and can be considered an alternative for conventional biochemical and molecular identification systems in a conventional microbiological laboratory. First, we evaluated MALDI-TOF MS using 327 clinical isolates previously cultured from patient materials and identified by conventional techniques (Vitek-II, API, and biochemical tests). Discrepancies were analyzed by molecular analysis of the 16S genes. Of 327 isolates, 95.1% were identified correctly to genus level, and 85.6% were identified to species level by MALDI-TOF MS. Second, we performed a prospective validation study, including 980 clinical isolates of bacteria and yeasts. Overall performance of MALDI-TOF MS was significantly better than conventional biochemical systems for correct species identification (92.2% and 83.1%, respectively) and produced fewer incorrect genus identifications (0.1% and 1.6%, respectively). Correct species identification by MALDI-TOF MS was observed in 97.7% of Enterobacteriaceae, 92% of nonfermentative Gram-negative bacteria, 94.3% of staphylococci, 84.8% of streptococci, 84% of a miscellaneous group (mainly Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella [HACEK]), and 85.2% of yeasts. MALDI-TOF MS had significantly better performance than conventional methods for species identification of staphylococci and genus identification of bacteria belonging to HACEK group. Misidentifications by MALDI-TOF MS were clearly associated with an absence of sufficient spectra from suitable reference strains in the MALDI-TOF MS database. We conclude that MALDI-TOF MS can be implemented easily for routine identification of bacteria (except for pneumococci and viridans streptococci) and yeasts in a medical microbiological laboratory. PMID:20053859

  17. High-throughput identification of bacteria and yeast by matrix-assisted laser desorption ionization-time of flight mass spectrometry in conventional medical microbiology laboratories.

    PubMed

    van Veen, S Q; Claas, E C J; Kuijper, Ed J

    2010-03-01

    Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is suitable for high-throughput and rapid diagnostics at low costs and can be considered an alternative for conventional biochemical and molecular identification systems in a conventional microbiological laboratory. First, we evaluated MALDI-TOF MS using 327 clinical isolates previously cultured from patient materials and identified by conventional techniques (Vitek-II, API, and biochemical tests). Discrepancies were analyzed by molecular analysis of the 16S genes. Of 327 isolates, 95.1% were identified correctly to genus level, and 85.6% were identified to species level by MALDI-TOF MS. Second, we performed a prospective validation study, including 980 clinical isolates of bacteria and yeasts. Overall performance of MALDI-TOF MS was significantly better than conventional biochemical systems for correct species identification (92.2% and 83.1%, respectively) and produced fewer incorrect genus identifications (0.1% and 1.6%, respectively). Correct species identification by MALDI-TOF MS was observed in 97.7% of Enterobacteriaceae, 92% of nonfermentative Gram-negative bacteria, 94.3% of staphylococci, 84.8% of streptococci, 84% of a miscellaneous group (mainly Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella [HACEK]), and 85.2% of yeasts. MALDI-TOF MS had significantly better performance than conventional methods for species identification of staphylococci and genus identification of bacteria belonging to HACEK group. Misidentifications by MALDI-TOF MS were clearly associated with an absence of sufficient spectra from suitable reference strains in the MALDI-TOF MS database. We conclude that MALDI-TOF MS can be implemented easily for routine identification of bacteria (except for pneumococci and viridans streptococci) and yeasts in a medical microbiological laboratory.

  18. Current Progress of a Finite Element Computational Fluid Dynamics Prediction of Flutter for the AeroStructures Test Wing

    NASA Technical Reports Server (NTRS)

    Arena, Andrew S., Jr.

    2002-01-01

    This progress report focuses on the use of the STructural Analysis RoutineS suite program, SOLIDS, input for the AeroStructures Test Wing. The AeroStructures Test Wing project as a whole is described. The use of the SOLIDS code to find the mode shapes of a structure is discussed. The frequencies, and the structural dynamics to which they relate are examined. The results of the CFD predictions are compared to experimental data from a Ground Vibration Test.

  19. Aero-Optical Wavefront Propagation and Refractive Fluid Interfaces in Large-Reynolds-Number Compressible Turbulent Flows

    DTIC Science & Technology

    2005-12-31

    are utilized with the eikonal equation of geometrical optics to propagate computationally the optical wavefronts in the near field. As long as the...aero- optical interactions. In terms of the refractive index field n and the optical path length (OPL), the eikonal equation is: |∇ (OPL)| = n , (9) (e.g...Final Report to the Air Force Office of Scientific Research AFOSR Grant FA9550-04-1-0386, Period: 06-01-2004 to 12-31-2005 Aero- Optical Wavefront

  20. Nonlinear feedback guidance law for aero-assisted orbit transfer maneuvers

    NASA Technical Reports Server (NTRS)

    Menon, P. K. A.

    1992-01-01

    Aero-assisted orbit transfer vehicles have the potential for significantly reducing the fuel requirements in certain classes of orbit transfer operations. Development of a nonlinear feedback guidance law for performing aero-assisted maneuvers that accomplish simultaneous change of all the orbital elements with least vehicle acceleration magnitude is discussed. The analysis is based on a sixth order nonlinear point-mass vehicle model with lift, bank angle, thrust and drag modulation as the control variables. The guidance law uses detailed vehicle aerodynamic and the atmosphere models in the feedback loop. Higher-order gravitational harmonics, planetary atmosphere rotation and ambient winds are included in the formulation. Due to modest computational requirements, the guidance law is implementable on-board an orbit transfer vehicle. The guidance performance is illustrated for three sets of boundary conditions.

  1. Global Mobile Satellite Service Interference Analysis for the AeroMACS

    NASA Technical Reports Server (NTRS)

    Wilson, Jeffrey D.; Apaza, Rafael D..; Hall, Ward; Phillips, Brent

    2013-01-01

    The AeroMACS (Aeronautical Mobile Airport Communications System), which is based on the IEEE 802.16-2009 mobile wireless standard, is envisioned as the wireless network which will cover all areas of airport surfaces for next generation air transportation. It is expected to be implemented in the 5091-5150 MHz frequency band which is also occupied by mobile satellite service uplinks. Thus the AeroMACS must be designed to avoid interference with this incumbent service. Simulations using Visualyse software were performed utilizing a global database of 6207 airports. Variations in base station and subscriber antenna distribution and gain pattern were examined. Based on these simulations, recommendations for global airport base station and subscriber antenna power transmission limitations are provided.

  2. Computational Aero-acoustics As a Tool For Turbo-machinery Noise Reduction

    NASA Technical Reports Server (NTRS)

    Dyson, Rodger W.

    2003-01-01

    This talk will provide an overview of the field of computational aero-acoustics and its use in fan noise prediction. After a brief history of computational fluid dynamics, some of the recent developments in computational aero-acoustics will be explored. Computational issues concerning sound wave production, propagation, and reflection in practical turbo-machinery applications will be discussed including: (a) High order/High Resolution Numerical Techniques. (b) High Resolution Boundary Conditions. [c] MIMD Parallel Computing. [d] Form of Governing Equations Useful for Simulations. In addition, the basic design of our Broadband Analysis Stator Simulator (BASS) code and its application to a 2 D rotor wake-stator interaction will be shown. An example of the noise produced by the wakes from a rotor impinging upon a stator cascade will be shown.

  3. Studies on dynamic characteristics of the joint in the aero-engine rotor system

    NASA Astrophysics Data System (ADS)

    Shuguo, Liu; Yanhong, Ma; Dayi, Zhang; Jie, Hong

    2012-05-01

    The joint as a major part of the aero-engine rotating shafts directly influences its rotordynamics and state stability. This paper studies the dynamic effects of structure parameters and the external load on the stiffness and contact state of the rotor joints with nonlinear finite-element method and experiments. And a sensitivity analysis of critical speeds and vibration modes with respect to typical parameters (stiffness of the spline joints) is performed with finite difference methods, through two approaches, i.e. relative sensitivity analysis and absolute sensitivity analysis. The study results show that the stiffness and contact state of joints vary with external loads and geometry structures, and affect the rotor system operating. It is advisable to consider the influence of the position, structural parameter and external load of the rotor joints on aero-engine structure dynamics design.

  4. Large Wind Turbine Rotor Design using an Aero-Elastic / Free-Wake Panel Coupling Code

    NASA Astrophysics Data System (ADS)

    Sessarego, Matias; Ramos-García, Néstor; Shen, Wen Zhong; Nørkær Sørensen, Jens

    2016-09-01

    Despite the advances in computing resources in the recent years, the majority of large wind-turbine rotor design problems still rely on aero-elastic codes that use blade element momentum (BEM) approaches to model the rotor aerodynamics. The present work describes an approach to wind-turbine rotor design by incorporating a higher-fidelity free-wake panel aero-elastic coupling code called MIRAS-FLEX. The optimization procedure includes a series of design load cases and a simple structural design code. Due to the heavy MIRAS-FLEX computations, a surrogate-modeling approach is applied to mitigate the overall computational cost of the optimization. Improvements in cost of energy, annual energy production, maximum flap-wise root bending moment, and blade mass were obtained for the NREL 5MW baseline wind turbine.

  5. Grain Selection during Directional Solidification of Aero-Engine Turbine Blades

    NASA Astrophysics Data System (ADS)

    Dong, Hongbiao

    2008-09-01

    The operating temperature of turbine blades in aero-engine engines has been demanded to increase for saving energy and increasing thrust. Turbine blades are made of nickel-base superalloys. Superalloys are a class of materials specifically developed for high temperature applications, particularly in the case of gas turbines for aero engines as well as land based power generation. Grain structure governs prolonged high temperature strength; this has formed the impetus both for alloy development as well as grain morphology, i.e. equiaxed—directional—single crystal solidification. In this paper, the evolution of grain structure and the control of crystal orientation in gas turbine blades are presented. The conditions leading to the solidification of columnar grain and single crystal blades are analysed, and techniques for producing columnar grain and single crystal blades in industry are reported.

  6. Study on aero-optical effect of a hypersonic missile infrared image guide

    NASA Astrophysics Data System (ADS)

    Han, Wei; Zhao, Yuejin; Hu, Xinqi

    2009-11-01

    When a hypersonic missile with a side mounted IR seeker is launched in the atmosphere, a serious aero-optical effect is formed and affects the quality of the detector's imaging. And in the course of the missile flight time,aero-optical effects changes over time, which makes real-time, accurate correction of optical distortion becomes very difficult. Therefore, it is necessary to study the relationship between the optical distortion and time.In this paper, Fluent,a computational fluid dynamics(CFD) internet applications is used to make researches on effect of optical transmission of the flow field outside the IR window. And a thermal finite element analysis (FEA) of an IR window is used to study the aerodynamic heat effect.

  7. Research on Aero-Thermodynamic Distortion Induced Structural Dynamic Response of Multi-Stage Compressor Blading.

    DTIC Science & Technology

    1983-06-01

    aerodynamic forced responses of gas turbine engine blading have been generated by a wide variety of aero- themodynamic distortion sources. These...To then relate the wake generated velocity profiles with the surface dynamic pressures on the instrumented vanes, the rotor exit velo- city triangles...quantities will be determined. As previously noted the cross hot-wire probe will be posi- tioned at mid rotor-stator axial spacing. To relate the

  8. Aero-/hydro-elastic stability of flexible panels: Prediction and control using localised spring support

    NASA Astrophysics Data System (ADS)

    Tan, B. H.; Lucey, A. D.; Howell, R. M.

    2013-12-01

    We study the effect of adding localised stiffness, via a spring support, on the stability of flexible panels subjected to axial uniform incompressible flow. Applications are considered that range from the hydro-elasticity of hull panels of high-speed ships to the aero-elasticity of glass panels in the curtain walls of high-rise buildings in very strong winds. A two-dimensional linear analysis is conducted using a hybrid of theoretical and computational methods that calculates the system eigen-states but can also be used to capture the transient behaviour that precedes these. We show that localised stiffening is a very effective means to increase the divergence-onset flow speed in both hydro- and aero-elastic applications. It is most effective when located at the mid-chord of the panel and there exists an optimum value of added stiffness beyond which further increases to the divergence-onset flow speed do not occur. For aero-elastic applications, localised stiffening can be used to replace the more destructive flutter instability that follows divergence at higher flow speeds by an extended range of divergence. The difference in eigen-solution morphology between aero- and hydro-elastic applications is highlighted, showing that for the former coalescence of two non-oscillatory divergence modes is the mechanism for flutter onset. This variation in solution morphology is mapped out in terms of a non-dimensional mass ratio. Finally, we present a short discussion of the applicability of the stabilisation strategy in a full three-dimensional system.

  9. Analysis of MMIC arrays for use in the ACTS Aero Experiment

    NASA Technical Reports Server (NTRS)

    Zimmerman, M.; Lee, R.; Rho, E.; Zaman, Z.

    1993-01-01

    The Aero Experiment is designed to demonstrate communication from an aircraft to an Earth terminal via the ACTS. This paper describes the link budget and antenna requirements for a 4.8 kbps full-duplex voice link at Ka-Band frequencies. Three arrays, one transmit array developed by TI and two receive arrays developed by GE and Boeing, were analyzed. The predicted performance characteristics of these arrays are presented and discussed in the paper.

  10. Whole-Field Measurements of Turbulent Flow for the Study of Aero-optical Effects

    DTIC Science & Technology

    2007-11-02

    Aerooptical phenomena associated with the propagation of optical beams and imaging through turbulent index-of-refraction fields have been investigated...Using simultaneous imaging of optical -beam distortion and the turbulent index-or-refraction field, we have documented near-field behavior, following...of TECHNOLOGY Pasadena, California 91125 Whole-field measurements of turbulent flow for the study of aero- optical effects Paul E. Dimotakis Air

  11. Results of a WINGDES2/AERO2S Flap Optimization for the TCA

    NASA Technical Reports Server (NTRS)

    Yaros, Steven F.

    1999-01-01

    The codes WINGDES2 and AERO2S were easy to obtain, and technical help was readily available. The codes have a long, well-documented history of successful optimizations of various aircraft configurations. The codes were easy to use, although specification of input data was time-consuming. The Run times were short, allowing the many runs necessary for the Suction Parameter matrix to be accomplished within a day or two. The results of the optimization appear to be reasonable.

  12. LES/RANS Modeling of Aero-Optical Effects in a Supersonic Cavity Flow

    DTIC Science & Technology

    2016-06-13

    which focused on simulations of the effects of heat release due to lasing chemistry on shock-train formation within chemical oxygen iodine lasers...complete some of the work proposed under the original statement of work. 2.0 INTRODUCTION Externally-mounted optical systems (e.g. an aircraft... systems , it is important to be able to predict and model these aero-optical effects. Figure 1. Schematic of cavity flow with optical reflector at

  13. Active Flutter Suppression Using Cooperative, High Frequency, Dynamic-Resonant Aero-Effectors

    DTIC Science & Technology

    2006-12-13

    Final 06/15/03-09/14/06 4. TITLE AND SUBTITLE Sa . CONTRACT NUMBER Active Flutter Suppression Using Cooperative, High Frequency, Dynamic Resonant Aero...maneuvering performance. Conventional active vibration control and flutter suppression systems are servo -hydraulic. Conventional servo -hydraulic...technology is burdened by a set of undesirable characteristics that effectively restrict their use to large aircraft. The servo -hydraulic based systems have

  14. Characterization of Surface Treated Aero Engine Alloys by Rayleigh Wave Velocity Dispersion

    NASA Astrophysics Data System (ADS)

    Köhler, B.; Barth, M.; Schubert, F.; Bamberg, J.; Baron, H.-U.

    2010-02-01

    In aero engines mechanically high stressed components made of high-strength alloys like IN718 and Ti6Al4V are usually surface treated by shot-peening. Other methods, e.g. laser-peening, deep rolling and low plasticity burnishing are also available. All methods introduce compres-sive residual stress desired for minimize sensitivity to fatigue or stress corrosion failure mechanisms, resulting in improved performance and increased lifetime of components. Beside that, also cold work is introduced in an amount varying from method to method. To determine the remaining life time of critical aero engine components like compressor and turbine discs, a quantitative non-destructive determination of compressive stresses is required. The opportunity to estimate residual stress in surface treated aero engine alloys by SAW phase velocity measurements has been re-examined. For that original engine relevant material IN718 has been used. Contrary to other publications a significant effect of the surface treatment to the sound velocity was observed which disappeared after thermal treatment. Also preliminary measurements of the acousto-elastic coefficient fit into this picture.

  15. Studies of acute and chronic radiation injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data

    SciTech Connect

    Grahn, D.; Wright, B.J.; Carnes, B.A.; Williamson, F.S.; Fox, C.

    1995-02-01

    A research reactor for exclusive use in experimental radiobiology was designed and built at Argonne National Laboratory in the 1960`s. It was located in a special addition to Building 202, which housed the Division of Biological and Medical Research. Its location assured easy access for all users to the animal facilities, and it was also near the existing gamma-irradiation facilities. The water-cooled, heterogeneous 200-kW(th) reactor, named JANUS, became the focal point for a range of radiobiological studies gathered under the rubic of {open_quotes}the JANUS program{close_quotes}. The program ran from about 1969 to 1992 and included research at all levels of biological organization, from subcellular to organism. More than a dozen moderate- to large-scale studies with the B6CF{sub 1} mouse were carried out; these focused on the late effects of whole-body exposure to gamma rays or fission neutrons, in matching exposure regimes. In broad terms, these studies collected data on survival and on the pathology observed at death. A deliberate effort was made to establish the cause of death. This archieve describes these late-effects studies and their general findings. The database includes exposure parameters, time of death, and the gross pathology and histopathology in codified form. A series of appendices describes all pathology procedures and codes, treatment or irradiation codes, and the manner in which the data can be accessed in the ORACLE database management system. A series of tables also presents summaries of the individual experiments in terms of radiation quality, sample sizes at entry, mean survival times by sex, and number of gross pathology and histopathology records.

  16. A mathematical model of Clostridium difficile transmission in medical wards and a cost-effectiveness analysis comparing different strategies for laboratory diagnosis and patient isolation

    PubMed Central

    Carmeli, Yehuda; Leshno, Moshe

    2017-01-01

    Background Clostridium difficile infection (CDI) is a common and potentially fatal healthcare-associated infection. Improving diagnostic tests and infection control measures may prevent transmission. We aimed to determine, in resource-limited settings, whether it is more effective and cost-effective to allocate resources to isolation or to diagnostics. Methods We constructed a mathematical model of CDI transmission based on hospital data (9 medical wards, 350 beds) between March 2010 and February 2013. The model consisted of three compartments: susceptible patients, asymptomatic carriers and CDI patients. We used our model results to perform a cost-effectiveness analysis, comparing four strategies that were different combinations of 2 test methods (the two-step test and uniform PCR) and 2 infection control measures (contact isolation in multiple-bed rooms or single-bed rooms/cohorting). For each strategy, we calculated the annual cost (of CDI diagnosis and isolation) for a decrease of 1 in the average daily number of CDI patients; the strategy of the two-step test and contact isolation in multiple-bed rooms was the reference strategy. Results Our model showed that the average number of CDI patients increased exponentially as the transmission rate increased. Improving diagnosis by adopting uniform PCR assay reduced the average number of CDI cases per day per 350 beds from 9.4 to 8.5, while improving isolation by using single-bed rooms reduced the number to about 1; the latter was cost saving. Conclusions CDI can be decreased by better isolation and more sensitive laboratory methods. From the hospital perspective, improving isolation is more cost-effective than improving diagnostics. PMID:28187144

  17. Solar Tower Experiments for Radiometric Calibration and Validation of Infrared Imaging Assets and Analysis Tools for Entry Aero-Heating Measurements

    NASA Technical Reports Server (NTRS)

    Splinter, Scott C.; Daryabeigi, Kamran; Horvath, Thomas J.; Mercer, David C.; Ghanbari, Cheryl M.; Ross, Martin N.; Tietjen, Alan; Schwartz, Richard J.

    2008-01-01

    The NASA Engineering and Safety Center sponsored Hypersonic Thermodynamic Infrared Measurements assessment team has a task to perform radiometric calibration and validation of land-based and airborne infrared imaging assets and tools for remote thermographic imaging. The IR assets and tools will be used for thermographic imaging of the Space Shuttle Orbiter during entry aero-heating to provide flight boundary layer transition thermography data that could be utilized for calibration and validation of empirical and theoretical aero-heating tools. A series of tests at the Sandia National Laboratories National Solar Thermal Test Facility were designed for this task where reflected solar radiation from a field of heliostats was used to heat a 4 foot by 4 foot test panel consisting of LI 900 ceramic tiles located on top of the 200 foot tall Solar Tower. The test panel provided an Orbiter-like entry temperature for the purposes of radiometric calibration and validation. The Solar Tower provided an ideal test bed for this series of radiometric calibration and validation tests because it had the potential to rapidly heat the large test panel to spatially uniform and non-uniform elevated temperatures. Also, the unsheltered-open-air environment of the Solar Tower was conducive to obtaining unobstructed radiometric data by land-based and airborne IR imaging assets. Various thermocouples installed on the test panel and an infrared imager located in close proximity to the test panel were used to obtain surface temperature measurements for evaluation and calibration of the radiometric data from the infrared imaging assets. The overall test environment, test article, test approach, and typical test results are discussed.

  18. Guidelines for safe work practices in human and animal medical diagnostic laboratories. Recommendations of a CDC-convened, Biosafety Blue Ribbon Panel.

    PubMed

    Miller, J Michael; Astles, Rex; Baszler, Timothy; Chapin, Kimberle; Carey, Roberta; Garcia, Lynne; Gray, Larry; Larone, Davise; Pentella, Michael; Pollock, Anne; Shapiro, Daniel S; Weirich, Elizabeth; Wiedbrauk, Danny

    2012-01-06

    Prevention of injuries and occupational infections in U.S. laboratories has been a concern for many years. CDC and the National Institutes of Health addressed the topic in their publication Biosafety in Microbiological and Biomedical Laboratories, now in its 5th edition (BMBL-5). BMBL-5, however, was not designed to address the day-to-day operations of diagnostic laboratories in human and animal medicine. In 2008, CDC convened a Blue Ribbon Panel of laboratory representatives from a variety of agencies, laboratory organizations, and facilities to review laboratory biosafety in diagnostic laboratories. The members of this panel recommended that biosafety guidelines be developed to address the unique operational needs of the diagnostic laboratory community and that they be science based and made available broadly. These guidelines promote a culture of safety and include recommendations that supplement BMBL-5 by addressing the unique needs of the diagnostic laboratory. They are not requirements but recommendations that represent current science and sound judgment that can foster a safe working environment for all laboratorians. Throughout these guidelines, quality laboratory science is reinforced by a common-sense approach to biosafety in day-to-day activities. Because many of the same diagnostic techniques are used in human and animal diagnostic laboratories, the text is presented with this in mind. All functions of the human and animal diagnostic laboratory--microbiology, chemistry, hematology, and pathology with autopsy and necropsy guidance--are addressed. A specific section for veterinary diagnostic laboratories addresses the veterinary issues not shared by other human laboratory departments. Recommendations for all laboratories include use of Class IIA2 biological safety cabinets that are inspected annually; frequent hand washing; use of appropriate disinfectants, including 1:10 dilutions of household bleach; dependence on risk assessments for many activities

  19. The status of medical laboratory towards of AFRO-WHO accreditation process in government and private health facilities in Addis Ababa, Ethiopia

    PubMed Central

    Mesfin, Eyob Abera; Taye, Bineyam; Belay, Getachew; Ashenafi, Aytenew

    2015-01-01

    Introduction The World Health Organization Regional Office for Africa (WHO AFRO) introduces a step wise incremental accreditation approach to improving quality of laboratory and it is a new initiative in Ethiopia and activities are performed for implementation of accreditation program. Methods Descriptive cross sectional study was conducted in 30 laboratory facilities including 6 laboratory sections to determine their status towards of accreditation using WHO AFRO accreditation checklist and 213 laboratory professionals were interviewed to assess their knowledge on quality system essentials and accreditation in Addis Ababa Ethiopia. Results Out of 30 laboratory facilities 1 private laboratory scored 156 (62%) points, which is the minimum required point for WHO accreditation and the least score was 32 (12.8%) points from government laboratory. The assessment finding from each section indicate that 2 Clinical chemistry (55.2% & 62.8%), 2 Hematology (55.2% & 62.8%), 2 Serology (55.2% & 62.8%), 2 Microbiology (55.2% & 62.4%), 1 Parasitology (62.8%) & 1 Urinalysis (61.6%) sections scored the minimum required point for WHO accreditation. The average score for government laboratories was 78.2 (31.2%) points, of these 6 laboratories were under accreditation process with 106.2 (42.5%) average score, while the private laboratories had 71.2 (28.5%) average score. Of 213 respondents 197 (92.5%) professionals had a knowledge on quality system essentials whereas 155 (72.8%) respondents on accreditation. Conclusion Although majority of the laboratory professionals had knowledge on quality system and accreditation, laboratories professionals were not able to practice the quality system properly and most of the laboratories had poor status towards the WHO accreditation process. Thus government as well as stakeholders should integrate accreditation program into planning and health policy. PMID:26889317

  20. Static and Wind Tunnel Aero-Performance Tests of NASA AST Separate Flow Nozzle Noise Reduction Configurations

    NASA Technical Reports Server (NTRS)

    Mikkelsen, Kevin L.; McDonald, Timothy J.; Saiyed, Naseem (Technical Monitor)

    2001-01-01

    This report presents the results of cold flow model tests to determine the static and wind tunnel performance of several NASA AST separate flow nozzle noise reduction configurations. The tests were conducted by Aero Systems Engineering, Inc., for NASA Glenn Research Center. The tests were performed in the Channels 14 and 6 static thrust stands and the Channel 10 transonic wind tunnel at the FluiDyne Aerodynamics Laboratory in Plymouth, Minnesota. Facility checkout tests were made using standard ASME long-radius metering nozzles. These tests demonstrated facility data accuracy at flow conditions similar to the model tests. Channel 14 static tests reported here consisted of 21 ASME nozzle facility checkout tests and 57 static model performance tests (including 22 at no charge). Fan nozzle pressure ratio varied from 1.4 to 2.0, and fan to core total pressure ratio varied from 1.0 to 1.19. Core to fan total temperature ratio was 1.0. Channel 10 wind tunnel tests consisted of 15 tests at Mach number 0.28 and 31 tests at Mach 0.8. The sting was checked out statically in Channel 6 before the wind tunnel tests. In the Channel 6 facility, 12 ASME nozzle data points were taken and 7 model data points were taken. In the wind tunnel, fan nozzle pressure ratio varied from 1.73 to 2.8, and fan to core total pressure ratio varied from 1.0 to 1.19. Core to fan total temperature ratio was 1.0. Test results include thrust coefficients, thrust vector angle, core and fan nozzle discharge coefficients, total pressure and temperature charging station profiles, and boat-tail static pressure distributions in the wind tunnel.

  1. Exploration Laboratory Analysis - ARC

    NASA Technical Reports Server (NTRS)

    Krihak, Michael K.; Fung, Paul P.

    2012-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk, Risk of Inability to Adequately Treat an Ill or Injured Crew Member, and ExMC Gap 4.05: Lack of minimally invasive in-flight laboratory capabilities with limited consumables required for diagnosing identified Exploration Medical Conditions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability in future exploration missions. Mission architecture poses constraints on equipment and procedures that will be available to treat evidence-based medical conditions according to the Space Medicine Exploration Medical Conditions List (SMEMCL). The SMEMCL provided diagnosis and treatment for the evidence-based medical conditions and hence, a basis for developing ELA functional requirements.

  2. Dynamical mechanism in aero-engine gas path system using minimum spanning tree and detrended cross-correlation analysis

    NASA Astrophysics Data System (ADS)

    Dong, Keqiang; Zhang, Hong; Gao, You

    2017-01-01

    Identifying the mutual interaction in aero-engine gas path system is a crucial problem that facilitates the understanding of emerging structures in complex system. By employing the multiscale multifractal detrended cross-correlation analysis method to aero-engine gas path system, the cross-correlation characteristics between gas path system parameters are established. Further, we apply multiscale multifractal detrended cross-correlation distance matrix and minimum spanning tree to investigate the mutual interactions of gas path variables. The results can infer that the low-spool rotor speed (N1) and engine pressure ratio (EPR) are main gas path parameters. The application of proposed method contributes to promote our understanding of the internal mechanisms and structures of aero-engine dynamics.

  3. The spectral analysis of an aero-engine assembly incorporating a squeeze-film damper

    NASA Technical Reports Server (NTRS)

    Holmes, R.; Dede, M. M.

    1989-01-01

    Aero-engine structures have very low inherent damping and so artificial damping is often introduced by pumping oil into annular gaps between the casings and the outer races of some or all of the rolling-element bearings supporting the rotors. The thin oil films so formed are called squeeze film dampers and they can be beneficial in reducing rotor vibration due to unbalance and keeping to reasonable limits the forces transmitted to the engine casing. However, squeeze-film dampers are notoriously non-linear and as a result can introduce into the assembly such phenomena as subharmonic oscillations, jumps and combination frequencies. The purpose of the research is to investigate such phenomena both theoretically and experimentally on a test facility reproducing the essential features of a medium-size aero engine. The forerunner of this work was published. It was concerned with the examination of a squeeze-film damper in series with housing flexibility when supporting a rotor. The structure represented to a limited extent the essentials of the projected Rolls Royce RB401 engine. That research demonstrated the ability to calculate the oil-film forces arising from the squeeze film from known motions of the bearing components and showed that the dynamics of a shaft fitted with a squeeze film bearing can be predicted reasonably accurately. An aero-engine will normally have at least two shafts and so in addition to the excitation forces which are synchronous with the rotation of one shaft, there will also be forces at other frequencies from other shafts operating on the squeeze-film damper. Theoretical and experimental work to consider severe loading of squeeze-film dampers and to include these additional effects are examined.

  4. AeroCom INSITU Project: Comparing modeled and measured aerosol optical properties

    NASA Astrophysics Data System (ADS)

    Andrews, Elisabeth; Schmeisser, Lauren; Schulz, Michael; Fiebig, Markus; Ogren, John; Bian, Huisheng; Chin, Mian; Easter, Richard; Ghan, Steve; Kokkola, Harri; Laakso, Anton; Myhre, Gunnar; Randles, Cynthia; da Silva, Arlindo; Stier, Phillip; Skeie, Ragnehild; Takemura, Toshihiko; van Noije, Twan; Zhang, Kai

    2016-04-01

    AeroCom, an open international collaboration of scientists seeking to improve global aerosol models, recently initiated a project comparing model output to in-situ, surface-based measurements of aerosol optical properties. The model/measurement comparison project, called INSITU, aims to evaluate the performance of a suite of AeroCom aerosol models with site-specific observational data in order to inform iterative improvements to model aerosol modules. Surface in-situ data has the unique property of being traceable to physical standards, which is an asset in accomplishing the overall goal of bettering the accuracy of aerosols processes and the predicative capability of global climate models. Here we compare dry, in-situ aerosol scattering and absorption data from ~75 surface, in-situ sites from various global aerosol networks (including NOAA, EUSAAR/ACTRIS and GAW) with a simulated optical properties from a suite of models participating in the AeroCom project. We report how well models reproduce aerosol climatologies for a variety of time scales, aerosol characteristics and behaviors (e.g., aerosol persistence and the systematic relationships between aerosol optical properties), and aerosol trends. Though INSITU is a multi-year endeavor, preliminary phases of the analysis suggest substantial model biases in absorption and scattering coefficients compared to surface measurements, though the sign and magnitude of the bias varies with location. Spatial patterns in the biases highlight model weaknesses, e.g., the inability of models to properly simulate aerosol characteristics at sites with complex topography. Additionally, differences in modeled and measured systematic variability of aerosol optical properties suggest that some models are not accurately capturing specific aerosol behaviors, for example, the tendency of in-situ single scattering albedo to decrease with decreasing aerosol extinction coefficient. The endgoal of the INSITU project is to identify specific

  5. Derivation of Aero-Induced Fluctuating Pressure Environments for Ares I-X

    NASA Technical Reports Server (NTRS)

    Yang, Michael Y.; Wilby, John F.

    2008-01-01

    A description is given of the external aero-inducted fluctuating pressure model which was fit and anchored to wind tunnel data from the past 40 years. This model is based upon the assumption that the flow around a vehicle can be divided into discrete flow zones with independent fluctuating pressure properties. The model is then used to derive fluctuating pressure environments during ascent for the Ares I-X test vehicle. A sensitivity study of the structural response to the spatial correlation of the fluctuating pressures is also performed.

  6. AeroPropulsoServoElasticity: Dynamic Modeling of the Variable Cycle Propulsion System

    NASA Technical Reports Server (NTRS)

    Kopasakis, George

    2012-01-01

    This presentation was made at the 2012 Fundamental Aeronautics Program Technical Conference and it covers research work for the Dynamic Modeling of the Variable cycle Propulsion System that was done under the Supersonics Project, in the area of AeroPropulsoServoElasticity. The presentation covers the objective for the propulsion system dynamic modeling work, followed by the work that has been done so far to model the variable Cycle Engine, modeling of the inlet, the nozzle, the modeling that has been done to model the affects of flow distortion, and finally presenting some concluding remarks and future plans.

  7. Fractional Order Modeling of Atmospheric Turbulence - A More Accurate Modeling Methodology for Aero Vehicles

    NASA Technical Reports Server (NTRS)

    Kopasakis, George

    2014-01-01

    The presentation covers a recently developed methodology to model atmospheric turbulence as disturbances for aero vehicle gust loads and for controls development like flutter and inlet shock position. The approach models atmospheric turbulence in their natural fractional order form, which provides for more accuracy compared to traditional methods like the Dryden model, especially for high speed vehicle. The presentation provides a historical background on atmospheric turbulence modeling and the approaches utilized for air vehicles. This is followed by the motivation and the methodology utilized to develop the atmospheric turbulence fractional order modeling approach. Some examples covering the application of this method are also provided, followed by concluding remarks.

  8. Radiative forcing of the direct aerosol effect from AeroCom Phase II simulations

    NASA Astrophysics Data System (ADS)

    Myhre, G.; Samset, B. H.; Schulz, M.; Balkanski, Y.; Bauer, S.; Berntsen, T. K.; Bian, H.; Bellouin, N.; Chin, M.; Diehl, T.; Easter, R. C.; Feichter, J.; Ghan, S. J.; Hauglustaine, D.; Iversen, T.; Kinne, S.; Kirkevåg, A.; Lamarque, J.-F.; Lin, G.; Liu, X.; Lund, M. T.; Luo, G.; Ma, X.; van Noije, T.; Penner, J. E.; Rasch, P. J.; Ruiz, A.; Seland, Ø.; Skeie, R. B.; Stier, P.; Takemura, T.; Tsigaridis, K.; Wang, P.; Wang, Z.; Xu, L.; Yu, H.; Yu, F.; Yoon, J.-H.; Zhang, K.; Zhang, H.; Zhou, C.

    2013-02-01

    We report on the AeroCom Phase II direct aerosol effect (DAE) experiment where 16 detailed global aerosol models have been used to simulate the changes in the aerosol distribution over the industrial era. All 16 models have estimated the radiative forcing (RF) of the anthropogenic DAE, and have taken into account anthropogenic sulphate, black carbon (BC) and organic aerosols (OA) from fossil fuel, biofuel, and biomass burning emissions. In addition several models have simulated the DAE of anthropogenic nitrate and anthropogenic influenced secondary organic aerosols (SOA). The model simulated all-sky RF of the DAE from total anthropogenic aerosols has a range from -0.58 to -0.02 Wm-2, with a mean of -0.27 Wm-2 for the 16 models. Several models did not include nitrate or SOA and modifying the estimate by accounting for this with information from the other AeroCom models reduces the range and slightly strengthens the mean. Modifying the model estimates for missing aerosol components and for the time period 1750 to 2010 results in a mean RF for the DAE of -0.35 Wm-2. Compared to AeroCom Phase I (Schulz et al., 2006) we find very similar spreads in both total DAE and aerosol component RF. However, the RF of the total DAE is stronger negative and RF from BC from fossil fuel and biofuel emissions are stronger positive in the present study than in the previous AeroCom study. We find a tendency for models having a strong (positive) BC RF to also have strong (negative) sulphate or OA RF. This relationship leads to smaller uncertainty in the total RF of the DAE compared to the RF of the sum of the individual aerosol components. The spread in results for the individual aerosol components is substantial, and can be divided into diversities in burden, mass extinction coefficient (MEC), and normalized RF with respect to AOD. We find that these three factors give similar contributions to the spread in results.

  9. Radiative forcing of the direct aerosol effect from AeroCom Phase II simulations

    NASA Astrophysics Data System (ADS)

    Myhre, G.; Samset, B. H.; Schulz, M.; Balkanski, Y.; Bauer, S.; Berntsen, T. K.; Bian, H.; Bellouin, N.; Chin, M.; Diehl, T.; Easter, R. C.; Feichter, J.; Ghan, S. J.; Hauglustaine, D.; Iversen, T.; Kinne, S.; Kirkevåg, A.; Lamarque, J.-F.; Lin, G.; Liu, X.; Luo, G.; Ma, X.; Penner, J. E.; Rasch, P. J.; Seland, Ø.; Skeie, R. B.; Stier, P.; Takemura, T.; Tsigaridis, K.; Wang, Z.; Xu, L.; Yu, H.; Yu, F.; Yoon, J.-H.; Zhang, K.; Zhang, H.; Zhou, C.

    2012-08-01

    We report on the AeroCom Phase II direct aerosol effect (DAE) experiment where 15 detailed global aerosol models have been used to simulate the changes in the aerosol distribution over the industrial era. All 15 models have estimated the radiative forcing (RF) of the anthropogenic DAE, and have taken into account anthropogenic sulphate, black carbon (BC) and organic aerosols (OA) from fossil fuel, biofuel, and biomass burning emissions. In addition several models have simulated the DAE of anthropogenic nitrate and anthropogenic influenced secondary organic aerosols (SOA). The model simulated all-sky RF of the DAE from total anthropogenic aerosols has a range from -0.58 to -0.02 W m-2, with a mean of -0.30 W m-2 for the 15 models. Several models did not include nitrate or SOA and modifying the estimate by accounting for this with information from the other AeroCom models reduces the range and slightly strengthens the mean. Modifying the model estimates for missing aerosol components and for the time period 1750 to 2010 results in a mean RF for the DAE of -0.39 W m-2. Compared to AeroCom Phase I (Schulz et al., 2006) we find very similar spreads in both total DAE and aerosol component RF. However, the RF of the total DAE is stronger negative and RF from BC from fossil fuel and biofuel emissions are stronger positive in the present study than in the previous AeroCom study. We find a tendency for models having a strong (positive) BC RF to also have strong (negative) sulphate or OA RF. This relationship leads to smaller uncertainty in the total RF of the DAE compared to the RF of the sum of the individual aerosol components. The spread in results for the individual aerosol components is substantial, and can be divided into diversities in burden, mass extinction coefficient (MEC), and normalized RF with respect to AOD. We find that these three factors give similar contributions to the spread in results.

  10. Aeronautical Satellite-Assisted Process for Information Exchange Through Network Technologies (Aero-SAPIENT) Conducted

    NASA Technical Reports Server (NTRS)

    Zernic, Michael J.

    2002-01-01

    Broadband satellite communications for aeronautics marries communication and network technologies to address NASA's goals in information technology base research and development, thereby serving the safety and capacity needs of the National Airspace System. This marriage of technology increases the interactivity between airborne vehicles and ground systems. It improves decision-making and efficiency, reduces operation costs, and improves the safety and capacity of the National Airspace System. To this end, a collaborative project called the Aeronautical Satellite Assisted Process for Information Exchange through Network Technologies, or Aero-SAPIENT, was conducted out of Tinker AFB, Oklahoma, during November and December 2000.

  11. Aero-servo-viscoelasticity theory: Lifting surfaces, plates, velocity transients, flutter, and instability

    NASA Astrophysics Data System (ADS)

    Merrett, Craig G.

    Modern flight vehicles are fabricated from composite materials resulting in flexible structures that behave differently from the more traditional elastic metal structures. Composite materials offer a number of advantages compared to metals, such as improved strength to mass ratio, and intentional material property anisotropy. Flexible aircraft structures date from the Wright brothers' first aircraft with fabric covered wooden frames. The flexibility of the structure was used to warp the lifting surface for flight control, a concept that has reappeared as aircraft morphing. These early structures occasionally exhibited undesirable characteristics during flight such as interactions between the empennage and the aft fuselage, or control problems with the elevators. The research to discover the cause and correction of these undesirable characteristics formed the first foray into the field of aeroelasticity. Aeroelasticity is the intersection and interaction between aerodynamics, elasticity, and inertia or dynamics. Aeroelasticity is well suited for metal aircraft, but requires expansion to improve its applicability to composite vehicles. The first is a change from elasticity to viscoelasticity to more accurately capture the solid mechanics of the composite material. The second change is to include control systems. While the inclusion of control systems in aeroelasticity lead to aero-servo-elasticity, more control possibilities exist for a viscoelastic composite material. As an example, during the lay-up of carbon-epoxy plies, piezoelectric control patches are inserted between different plies to give a variety of control options. The expanded field is called aero-servo-viscoelasticity. The phenomena of interest in aero-servo-viscoelasticity are best classified according to the type of structure considered, either a lifting surface or a panel, and the type of dynamic stability present. For both types of structures, the governing equations are integral

  12. A Preliminary to War: The 1st Aero Squadron and the Mexican Punitive Expedition of 1916

    DTIC Science & Technology

    2003-01-01

    ordered a reconnaissance along the Mexican Northwestern railroad south toward Cumbre Pass in the Sierra Madre mountains. Dodd and Foulois flew this...Casas Grandes and Galeana Valleys ranged between 6,000 and 7,000 feet, and that Cumbre Pass lay at about 9,000 feet. All of these altitudes were higher...of the Cumbre Pass tunnel, but could go no farther. For two hours, 25 The 1st Aero Squadron in Mexico; probably following a mission by Signal Corps No

  13. Performance Analysis of the AeroTP Transport Protocol for Highly-Dynamic Airborne Telemetry Networks

    DTIC Science & Technology

    2011-06-03

    Acknowledgment Options.” RFC 2018 (Proposed Standard ), Oct. 1996. [11] “The ns- 3 network simulator.” http://www.nsnam.org, July 2009. [12] M. AL-Enazi, S. A. Gogi...AFFTC-PA- 11146 Performance Analysis of the AeroTP Transport Protocol for Highly-Dynamic Airborne Telemetry Networks James P.G. Sterbenz...Kamakshi Sirisha Pathapati, Truc Anh N. Nguyen, Justin P. Rohrer AIR FORCE FLIGHT TEST CENTER EDWARDS AFB, CA JUNE 3 , 2011 A F F T C

  14. Radiative forcing of the direct aerosol effect from AeroCom Phase II simulations

    SciTech Connect

    Myhre, G.; Samset, B. H.; Schulz, M.; Balkanski, Y.; Bauer, S.; Berntsen, T. K.; Bian, H.; Bellouin, N.; Chin, M.; Diehl, T.; Easter, R. C.; Feichter, J.; Ghan, S. J.; Hauglustaine, D.; Iversen, T.; Kinne, S.; Kirkevåg, A.; Lamarque, J. -F.; Lin, G.; Liu, X.; Lund, M. T.; Luo, G.; Ma, X.; van Noije, T.; Penner, J. E.; Rasch, P. J.; Ruiz, A.; Seland, Ø.; Skeie, R. B.; Stier, P.; Takemura, T.; Tsigaridis, K.; Wang, P.; Wang, Z.; Xu, L.; Yu, H.; Yu, F.; Yoon, J. -H.; Zhang, K.; Zhang, H.; Zhou, C.

    2013-01-01

    We report on the AeroCom Phase II direct aerosol effect (DAE) experiment where 16 detailed global aerosol models have been used to simulate the changes in the aerosol distribution over the industrial era. All 16 models have estimated the radiative forcing (RF) of the anthropogenic DAE, and have taken into account anthropogenic sulphate, black carbon (BC) and organic aerosols (OA) from fossil fuel, biofuel, and biomass burning emissions. In addition several models have simulated the DAE of anthropogenic nitrate and anthropogenic influenced secondary organic aerosols (SOA). The model simulated all-sky RF of the DAE from total anthropogenic aerosols has a range from -0.58 to -0.02 Wm-2, with a mean of -0.27 Wm-2 for the 16 models. Several models did not include nitrate or SOA and modifying the estimate by accounting for this with information from the other AeroCom models reduces the range and slightly strengthens the mean. Modifying the model estimates for missing aerosol components and for the time period 1750 to 2010 results in a mean RF for the DAE of -0.35 Wm-2. Compared to AeroCom Phase I (Schulz et al., 2006) we find very similar spreads in both total DAE and aerosol component RF. However, the RF of the total DAE is stronger negative and RF from BC from fossil fuel and biofuel emissions are stronger positive in the present study than in the previous AeroCom study. We find a tendency for models having a strong (positive) BC RF to also have strong (negative) sulphate or OA RF. This relationship leads to smaller uncertainty in the total RF of the DAE compared to the RF of the sum of the individual aerosol components. The spread in results for the individual aerosol components is substantial, and can be divided into diversities in burden, mass extinction coefficient (MEC), and normalized RF with respect to AOD. We find that these three factors give similar contributions to the spread in results.

  15. The Brief Introduction of Different Laser Diagnostics Methods Used in Aero-Engine Combustion Research

    NASA Astrophysics Data System (ADS)

    Xing, Fei; Song, Ge; Ruan, Can; Zhao, Jian; Yang, Yongjun

    2016-06-01

    Combustion test diagnose has always been one of the most important technologies for the development of aerospace engineering. Laser diagnostics techniques developed quickly in the past several years. They are used to measure the parameters of the combustion flow field such as velocity, temperature, components concentration with high space and time resolution and brought no disturbance. Planar Laser-Induced Fluorescence, Coherent Anti-Stokes Raman Scattering, Tunable Diode Laser Absorption Spectroscopy and Raman Scattering were introduced systemically in this paper. After analysis their own advantages and disadvantages, it is believed that Raman Scattering system is more suitable for research activities on aero-engine combustion systems.

  16. United States Air Force Summer Research Program -- 1993. Volume 16. Arnold Engineering Development Center. Frank J. Seiler Research Laboratory. Wilford Hall Medical Center

    DTIC Science & Technology

    1993-12-01

    Master Index For High School Apprentices Ackermann, Laura Laboratory: PL/LI 7801 Wilshire H Vol-Paqe No: 13- 5 La Cueva High School Albuquerque, 1HK...Wilshire Blvd. Vol-Page No: 13- 6 La Cueva High School Albuquerque, M 87122-0000 Felderman, James Laboratory: AEDC/ N. Jackson St. Vol-Page No: 16- 2...500 Z. Franklin St. Vol-Page No: 15-23 Centerville Sigh School Centerville, OH 45459-0000 Gonzalez , Christopher Laboratory: AL/OK 1400 Jackson-Keller

  17. United States Air Force Summer Research Program -- 1993. Volume 6. Arnold Engineering Development Center, Frank J. Seiler Research Laboratory, Wilford Hall Medical Center

    DTIC Science & Technology

    1993-12-01

    Science Dept, CMI. gz cs, PhD Laboratory: PL/VT 3200 Willow Creek Road Embry-Riddle Aeronautical Univ Vol-Page No: 3-24 Prescott , AZ 86301-0000 Belle... Prescott , AZ 86301-0000 Bhuyan, Jay Field: computer Science Assistant Professor, PhD Laboratory: PL/WS Dept. ofComputer Science Tuskegee University...No: 5- 2 Prescott , AZ 86301-3720 Cundari, Thomas Field: Department of Chemistry Assistant Professor, PhD Laboratory: PL/RK Jim Smith Building MAmphis

  18. NASA Johnson Space Center Medical Licensing Opportunities

    NASA Technical Reports Server (NTRS)

    Hernandez-Moya, Sonia

    2009-01-01

    This presentation reviews patented medical items that are available for licensing in the areas of Laboratory Technologies, Medical Devices, Medical Equipment and other technologies that are of interest to the medical community.

  19. Wind tunnel validation of AeroDyn within LIFES50+ project: imposed Surge and Pitch tests

    NASA Astrophysics Data System (ADS)

    Bayati, I.; Belloli, M.; Bernini, L.; Zasso, A.

    2016-09-01

    This paper presents the first set of results of the steady and unsteady wind tunnel tests, performed at Politecnico di Milano wind tunnel, on a 1/75 rigid scale model of the DTU 10 MW wind turbine, within the LIFES50+ project. The aim of these tests is the validation of the open source code AeroDyn developed at NREL. Numerical and experimental steady results are compared in terms of thrust and torque coefficients, showing good agreement, as well as for unsteady measurements gathered with a 2 degree-of-freedom test rig, capable of imposing the displacements at the base of the model, and providing the surge and pitch motion of the floating offshore wind turbine (FOWT) scale model. The measurements of the unsteady test configuration are compared with AeroDyn/Dynin module results, implementing the generalized dynamic wake (GDW) model. Numerical and experimental comparison showed similar behaviours in terms of non linear hysteresis, however some discrepancies are herein reported and need further data analysis and interpretations about the aerodynamic integral quantities, with a special attention to the physics of the unsteady phenomenon.

  20. Dynamic similarity design method for an aero-engine dualrotor test rig

    NASA Astrophysics Data System (ADS)

    Miao, H.; Zang, C.; Friswell, M. I.

    2016-09-01

    This paper presents a dynamic similarity design method to design a scale dynamic similarity model (DSM) for a dual-rotor test rig of an aero-engine. Such a test rig is usually used to investigate the major dynamic characteristics of the full-size model (FSM) and to reduce the testing cost and time for experiments on practical aero engine structures. Firstly, the dynamic equivalent model (DEM) of a dual-rotor system is modelled based on its FSM using parametric modelling, and the first 10 frequencies and mode shapes of the DEM are updated to agree with the FSM by modifying the geometrical shapes of the DEM. Then, the scaling laws for the relative parameters (such as geometry sizes of the rotors, stiffness of the supports, inherent properties) between the DEM and its scale DSM were derived from their equations of motion, and the scaling factors of the above-mentioned parameters are determined by the theory of dimensional analyses. After that, the corresponding parameters of the scale DSM of the dual-rotor test rig can be determined by using the scaling factors. In addition, the scale DSM is further updated by considering the coupling effect between the disks and shafts. Finally, critical speed and unbalance response analysis of the FSM and the updated scale DSM are performed to validate the proposed method.

  1. Aero-Propulsion Technology (APT) Task V Low Noise ADP Engine Definition Study

    NASA Technical Reports Server (NTRS)

    Holcombe, V.

    2003-01-01

    A study was conducted to identify and evaluate noise reduction technologies for advanced ducted prop propulsion systems that would allow increased capacity operation and result in an economically competitive commercial transport. The study investigated the aero/acoustic/structural advancements in fan and nacelle technology required to match or exceed the fuel burned and economic benefits of a constrained diameter large Advanced Ducted Propeller (ADP) compared to an unconstrained ADP propulsion system with a noise goal of 5 to 10 EPNDB reduction relative to FAR 36 Stage 3 at each of the three measuring stations namely, takeoff (cutback), approach and sideline. A second generation ADP was selected to operate within the maximum nacelle diameter constrain of 160 deg to allow installation under the wing. The impact of fan and nacelle technologies of the second generation ADP on fuel burn and direct operating costs for a typical 3000 nm mission was evaluated through use of a large, twin engine commercial airplane simulation model. The major emphasis of this study focused on fan blade aero/acoustic and structural technology evaluations and advanced nacelle designs. Results of this study have identified the testing required to verify the interactive performance of these components, along with noise characteristics, by wind tunnel testing utilizing and advanced interaction rig.

  2. Physics and Measurement of Aero-Optical Effects: Past and Present

    NASA Astrophysics Data System (ADS)

    Jumper, Eric J.; Gordeyev, Stanislav

    2017-01-01

    The field of aero-optics is devoted to the study of the effects of turbulent flow fields on laser beams projected from airborne laser systems. This article reviews the early and present periods of research in aero-optics. Both periods generated impressive amounts of research activity; however, the types and amount of data differ greatly in accuracy, quality, and type owing to the development of new types of instrumentation available to collect and analyze the aberrated wave fronts of otherwise collimated laser beams projected through turbulent compressible flow fields of the type that form over beam directors. This review traces the activities and developments associated with both periods but particularly focuses on the development of modern high-bandwidth wave-front sensors used in the present research period. We describe how these modern wave-front data are collected and analyzed and the fluid mechanic information that can be gleaned from them; the use of these data in the fundamental study of turbulence is emphasized.

  3. Aerosciences, Aero-Propulsion and Flight Mechanics Technology Development for NASA's Next Generation Launch Technology Program

    NASA Technical Reports Server (NTRS)

    Cockrell, Charles E., Jr.

    2003-01-01

    The Next Generation Launch Technology (NGLT) program, Vehicle Systems Research and Technology (VSR&T) project is pursuing technology advancements in aerothermodynamics, aeropropulsion and flight mechanics to enable development of future reusable launch vehicle (RLV) systems. The current design trade space includes rocket-propelled, hypersonic airbreathing and hybrid systems in two-stage and single-stage configurations. Aerothermodynamics technologies include experimental and computational databases to evaluate stage separation of two-stage vehicles as well as computational and trajectory simulation tools for this problem. Additionally, advancements in high-fidelity computational tools and measurement techniques are being pursued along with the study of flow physics phenomena, such as boundary-layer transition. Aero-propulsion technology development includes scramjet flowpath development and integration, with a current emphasis on hypervelocity (Mach 10 and above) operation, as well as the study of aero-propulsive interactions and the impact on overall vehicle performance. Flight mechanics technology development is focused on advanced guidance, navigation and control (GN&C) algorithms and adaptive flight control systems for both rocket-propelled and airbreathing vehicles.

  4. A rapid method to achieve aero-engine blade form detection.

    PubMed

    Sun, Bin; Li, Bing

    2015-06-01

    This paper proposes a rapid method to detect aero-engine blade form, according to the characteristics of an aero-engine blade surface. This method first deduces an inclination error model in free-form surface measurements based on the non-contact laser triangulation principle. Then a four-coordinate measuring system was independently developed, a special fixture was designed according to the blade shape features, and a fast measurement of the blade features path was planned. Finally, by using the inclination error model for correction of acquired data, the measurement error that was caused by tilt form is compensated. As a result the measurement accuracy of the Laser Displacement Sensor was less than 10 μm. After the experimental verification, this method makes full use of optical non-contact measurement fast speed, high precision and wide measuring range of features. Using a standard gauge block as a measurement reference, the coordinate system conversion data is simple and practical. It not only improves the measurement accuracy of the blade surface, but also its measurement efficiency. Therefore, this method increases the value of the measurement of complex surfaces.

  5. A Rapid Method to Achieve Aero-Engine Blade Form Detection

    PubMed Central

    Sun, Bin; Li, Bing

    2015-01-01

    This paper proposes a rapid method to detect aero-engine blade form, according to the characteristics of an aero-engine blade surface. This method first deduces an inclination error model in free-form surface measurements based on the non-contact laser triangulation principle. Then a four-coordinate measuring system was independently developed, a special fixture was designed according to the blade shape features, and a fast measurement of the blade features path was planned. Finally, by using the inclination error model for correction of acquired data, the measurement error that was caused by tilt form is compensated. As a result the measurement accuracy of the Laser Displacement Sensor was less than 10 μm. After the experimental verification, this method makes full use of optical non-contact measurement fast speed, high precision and wide measuring range of features. Using a standard gauge block as a measurement reference, the coordinate system conversion data is simple and practical. It not only improves the measurement accuracy of the blade surface, but also its measurement efficiency. Therefore, this method increases the value of the measurement of complex surfaces. PMID:26039420

  6. Dynamics of fine particles and photo-oxidants in the Eastern Mediterranean (SUB-AERO)

    NASA Astrophysics Data System (ADS)

    Lazaridis, M.; Eleftheriadis, K.; Smolik, J.; Colbeck, I.; Kallos, G.; Drossinos, Y.; Zdimal, V.; Vecera, Z.; Mihalopoulos, N.; Mikuska, P.; Bryant, C.; Housiadas, C.; Spyridaki, A.; Astitha, Marina; Havranek, V.

    As part of the European project SUB-AERO, comprehensive aerosol and gaseous pollutant measurement campaigns were performed at the Finokalia station (July 2000 and January 2001) on the island of Crete (Greece) in combination with boat measurements in the eastern part of the Mediterranean area. The measurements were performed with the participation of nine European research institutions. The objective of the measurement campaigns was to evaluate and assess the spatial and temporal variability of photochemical pollutants and fine particles. The current overview paper presents the framework and main results of the measurements and modelling studies performed during the project. Extensive measurements of gaseous and atmospheric-aerosol physical, chemical and optical characteristics were performed during the measurement campaigns in conjunction with detailed chemical analyses of the aerosol species. Along with the experimental work mesoscale modelling, using a combination of the UAM-AERO air quality model together with the RAMS prognostic meteorological model, was used to reveal the dynamics of particulate matter and photo-oxidants. Furthermore, regional chemistry transport models were applied to determine the background and initial conditions for the mesoscale modelling.

  7. Digital holographic interferometry for characterizing deformable mirrors in aero-optics

    NASA Astrophysics Data System (ADS)

    Trolinger, James D.; Hess, Cecil F.; Razavi, Payam; Furlong, Cosme

    2016-08-01

    Measuring and understanding the transient behavior of a surface with high spatial and temporal resolution are required in many areas of science. This paper describes the development and application of a high-speed, high-dynamic range, digital holographic interferometer for high-speed surface contouring with fractional wavelength precision and high-spatial resolution. The specific application under investigation here is to characterize deformable mirrors (DM) employed in aero-optics. The developed instrument was shown capable of contouring a deformable mirror with extremely high-resolution at frequencies exceeding 40 kHz. We demonstrated two different procedures for characterizing the mechanical response of a surface to a wide variety of input forces, one that employs a high-speed digital camera and a second that employs a low-speed, low-cost digital camera. The latter is achieved by cycling the DM actuators with a step input, producing a transient that typically lasts up to a millisecond before reaching equilibrium. Recordings are made at increasing times after the DM initiation from zero to equilibrium to analyze the transient. Because the wave functions are stored and reconstructable, they can be compared with each other to produce contours including absolute, difference, and velocity. High-speed digital cameras recorded the wave functions during a single transient at rates exceeding 40 kHz. We concluded that either method is fully capable of characterizing a typical DM to the extent required by aero-optical engineers.

  8. Skylab medical operational support

    NASA Technical Reports Server (NTRS)

    Primeaux, G. R.; Spross, F. R.

    1974-01-01

    To support the medical research and the maintenance of crew health during the three Skylab missions, a medical operational support team was organized. The functions of this team ranged from medical data management to medical systems engineering monitoring during the flights. The capability to expand preflight and postflight medical research and analysis was supplied through the use of the Skylab mobile laboratories. These mobile laboratories were not only capable of being transported to the recovery ship for postflight use, but also served as a preflight test area for gathering crewman baseline data. The laboratories contained experiment hardware identical to that of the flight orbital workshop and a laboratory diagnostic facility that duplicated many of the capabilities of ground-based clinical laboratories.

  9. Usefulness of EC4 essential criteria for quality systems of medical laboratories as guideline to the ISO 15189 and ISO 17025 documents. European Community Confederation of Clinical Chemistry (EC4) Working Group on Harmonisation of Quality Systems and Accreditation.

    PubMed

    Jansen, R T; Kenny, D; Blaton, V; Burnett, D; Huisman, W; Plebani, M; Queraltó, J M; Zérah, S; van Lieshout, J

    2000-10-01

    Many medical laboratories have made a start with the introduction of quality management systems. However, it is still not clear against which standards such systems should be measured. The existing ISO and CEN standards do not cover essential aspects of medical laboratories. The publication of the EC4 Essential Criteria has stimulated the development of the ISO/Draft International Standard 15189. This standard seems adequate for our type of laboratories. However, it is not easy to read. The EC4 Essential Criteria could well serve as a guide, covering additional aspects, e.g. on total quality management and budget management as required in the EFQM model, that are not (yet) included in the ISO standard. In the present article the EC4 Essential Criteria are cross-referenced with two new international ISO standards, ISO/FDIS 15189 and ISO/FDIS 17025, the latter being the successor of ISO guide 25 and EN 45000. Both new ISO documents are in compliance with the new ISO 9000:2000 standard.

  10. 75 FR 22512 - Airworthiness Directives; Piaggio Aero Industries S.p.A. Model PIAGGIO P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... Industries S.p.A. Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation Administration (FAA), Department of....regulations.gov ; or in person at the Docket Management Facility between 9 a.m. and 5 p.m., Monday through... 2. The FAA amends Sec. 39.13 by adding the following new AD: 2010-09-09 Piaggio Aero Industries...

  11. 75 FR 67639 - Airworthiness Directives; Piaggio Aero Industries S.p.A Model PIAGGIO P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Industries S.p.A Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airplane Flight Manual, stating that the towing bar P/N 01-1227-0000 or similar ferromagnetic masses are... maintenance requirements and/or airworthiness limitations developed by Piaggio Aero Industries S.p.A....

  12. 76 FR 7694 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... Docket Management Facility between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. The..., etc. for PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 airplanes. As published, the...

  13. 76 FR 10224 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... this AD, contact Piaggio Aero Industries S.p.A., Via Cibrario, 4-16154 Genoa, Italy; phone: +39 010... that the towing bar P/N 01-1227-0000 or similar ferromagnetic masses are prohibited to be carried...

  14. 76 FR 36980 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ...-013-AD; Amendment 39-16697; AD 2011-09-51] RIN 2120-AA64 Airworthiness Directives; PIAGGIO AERO...: Final rule; correction. ] SUMMARY: The FAA is correcting an airworthiness directive (AD) that published in the Federal Register. That AD applies to the products listed above. The AD number in the...

  15. Medical waste management plan.

    SciTech Connect

    Lane, Todd W.; VanderNoot, Victoria A.

    2004-12-01

    This plan describes the process for managing research generated medical waste at Sandia National Laboratories/California. It applies to operations at the Chemical and Radiation Detection Laboratory (CRDL), Building 968, and other biosafety level 1 or 2 activities at the site. It addresses the accumulation, storage, treatment and disposal of medical waste and sharps waste. It also describes the procedures to comply with regulatory requirements and SNL policies applicable to medical waste.

  16. Skylab mobile laboratory

    NASA Technical Reports Server (NTRS)

    Primeaux, G. R.; Larue, M. A.

    1975-01-01

    The Skylab mobile laboratory was designed to provide the capability to obtain necessary data on the Skylab crewmen 30 days before lift-off, within 1 hour after recovery, and until preflight physiological baselines were reattained. The mobile laboratory complex consisted of six laboratories that supported cardiovascular, metabolic, nutrition and endocrinology, operational medicine, blood, and microbiology experiments; a utility package; and two shipping containers. The objectives and equipment requirements of the Skylab mobile laboratory and the data acquisition systems are discussed along with processes such as permanently mounting equipment in the individual laboratories and methods of testing and transporting the units. The operational performance, in terms of amounts of data collected, and the concept of mobile laboratories for medical and scientific experiments are evaluated. The Skylab mobile laboratory succeeded in facilitating the data collection and sample preservation associated with the three Skylab manned flights.

  17. Experimental investigation on aero-optical aberration of shock wave/boundary layer interactions

    NASA Astrophysics Data System (ADS)

    Ding, Haolin; Yi, Shihe; Fu, Jia; He, Lin

    2016-10-01

    After streaming through the flow field which including the expansion, shock wave, boundary, etc., the optical wave would be distorted by fluctuations in the density field. Interactions between laminar/turbulent boundary layer and shock wave contain large number complex flow structures, which offer a condition for studying the influences that different flow structures of the complex flow field have on the aero-optical aberrations. Interactions between laminar/turbulent boundary layer and shock wave are investigated in a Mach 3.0 supersonic wind tunnel, based on nanoparticle-tracer planar laser scattering (NPLS) system. Boundary layer separation/attachment, induced suppression waves, induced shock wave, expansion fan and boundary layer are presented by NPLS images. Its spatial resolution is 44.15 μm/pixel. Time resolution is 6ns. Based on the NPLS images, the density fields with high spatial-temporal resolution are obtained by the flow image calibration, and then the optical path difference (OPD) fluctuations of the original 532nm planar wavefront are calculated using Ray-tracing theory. According to the different flow structures in the flow field, four parts are selected, (1) Y=692 600pixel; (2) Y=600 400pixel; (3) Y=400 268pixel; (4) Y=268 0pixel. The aerooptical effects of different flow structures are quantitatively analyzed, the results indicate that: the compressive waves such as incident shock wave, induced shock wave, etc. rise the density, and then uplift the OPD curve, but this kind of shock are fixed in space position and intensity, the aero-optics induced by it can be regarded as constant; The induced shock waves are induced by the coherent structure of large size vortex in the interaction between turbulent boundary layer, its unsteady characteristic decides the induced waves unsteady characteristic; The space position and intensity of the induced shock wave are fixed in the interaction between turbulent boundary layer; The boundary layer aero-optics are

  18. Radiative Forcing of the Direct Aerosol Effect from AeroCom Phase II Simulations

    NASA Technical Reports Server (NTRS)

    Myhre, G.; Samset, B. H.; Schulz, M.; Balkanski, Y.; Bauer, S.; Berntsen, T. K.; Bian, H.; Bellouin, N.; Chin, M.; Diehl, T.; Easter, R. C.; Feichter, J.; Ghan, S. J.; Hauglustaine, D.; Iversen, T.; Kinne, S.; Kirkevag, A.; Lamarque, J.-F.; Lin, G.; Liu, X.; Lund, M. T.; Luo, G.; Ma, X.; vanNoije, T.; Penner, J. E.; Rasch, P. J.; Ruiz, A.; Seland, O.; Skeie, R. B.; Stier, P.; Takemura, T.; Tsigaridis, K.; Wang, P.; Wang, Z.; Xu, L.; Yu, H.; Yu, F.; Yoon, J. -H.; Zhang, K.; Zhang, H.; Zhou, C.

    2013-01-01

    We report on the AeroCom Phase II direct aerosol effect (DAE) experiment where 16 detailed global aerosol models have been used to simulate the changes in the aerosol distribution over the industrial era. All 16 models have estimated the radiative forcing (RF) of the anthropogenic DAE, and have taken into account anthropogenic sulphate, black carbon (BC) and organic aerosols (OA) from fossil fuel, biofuel, and biomass burning emissions. In addition several models have simulated the DAE of anthropogenic nitrate and anthropogenic influenced secondary organic aerosols (SOA). The model simulated all-sky RF of the DAE from total anthropogenic aerosols has a range from -0.58 to -0.02 W m(sup-2), with a mean of -0.27 W m(sup-2 for the 16 models. Several models did not include nitrate or SOA and modifying the estimate by accounting for this with information slightly strengthens the mean. Modifying the model estimates for missing aerosol components and for the time period 1750 to 2010 results in a mean RF for the DAE of -0.35 W m(sup-2). Compared to AeroCom Phase I (Schulz et al., 2006) we find very similar spreads in both total DAE and aerosol component RF. However, the RF of the total DAE is stronger negative and RF from BC from fossil fuel and biofuel emissions are stronger positive in the present study than in the previous AeroCom study.We find a tendency for models having a strong (positive) BC RF to also have strong (negative) sulphate or OA RF. This relationship leads to smaller uncertainty in the total RF of the DAE compared to the RF of the sum of the individual aerosol components. The spread in results for the individual aerosol components is substantial, and can be divided into diversities in burden, mass extinction coefficient (MEC), and normalized RF with respect to AOD. We find that these three factors give similar contributions to the spread in results

  19. An AeroCom assessment of black carbon in Arctic snow and sea ice

    SciTech Connect

    Jiao, C.; Flanner, M. G.; Balkanski, Y.; Bauer, S. E.; Bellouin, N.; Berntsen, T. K.; Bian, H.; Carslaw, K. S.; Chin, M.; De Luca, N.; Diehl, T.; Ghan, S. J.; Iversen, T.; Kirkevåg, A.; Koch, D.; Liu, X.; Mann, G. W.; Penner, J. E.; Pitari, G.; Schulz, M.; Seland, Ø.; Skeie, R. B.; Steenrod, S. D.; Stier, P.; Takemura, T.; Tsigaridis, K.; van Noije, T.; Yun, Y.; Zhang, K.

    2014-01-01

    Though many global aerosols models prognose surface deposition, only a few models have been used to directly simulate the radiative effect from black carbon (BC) deposition to snow and sea ice. In this paper, we apply aerosol deposition fields from 25 models contributing to two phases of the Aerosol Comparisons between Observations and Models (AeroCom) project to simulate and evaluate within-snow BC concentrations and radiative effect in the Arctic. We accomplish this by driving the offline land and sea ice components of the Community Earth System Model with different deposition fields and meteorological conditions from 2004 to 2009, during which an extensive field campaign of BC measurements in Arctic snow occurred. We find that models generally underestimate BC concentrations in snow in northern Russia and Norway, while overestimating BC amounts elsewhere in the Arctic. Although simulated BC distributions in snow are poorly correlated with measurements, mean values are reasonable. The multi-model mean (range) bias in BC concentrations, sampled over the same grid cells, snow depths, and months of measurements, are -4.4 (-13.2 to +10.7) ng g-1 for an earlier phase of AeroCom models (phase I), and +4.1 (-13.0 to +21.4) ng g-1 for a more recent phase of AeroCom models (phase II), compared to the observational mean of 19.2 ng g-1. Factors determining model BC concentrations in Arctic snow include Arctic BC emissions, transport of extra-Arctic aerosols, precipitation, deposition efficiency of aerosols within the Arctic, and meltwater removal of particles in snow. Sensitivity studies show that the model–measurement evaluation is only weakly affected by meltwater scavenging efficiency because most measurements were conducted in non-melting snow. The Arctic (60–90° N) atmospheric residence time for BC in phase II models ranges from 3.7 to 23.2 days, implying large inter-model variation in local BC deposition efficiency. Combined with

  20. A guidance-motivated sensitivity analysis of an aero-assisted boost vehicle

    NASA Technical Reports Server (NTRS)

    Taylor, L. W.; Gracey, C.; Armstrong, C. D.

    1986-01-01

    A simple model of an aero-assisted booster is used to examine the contributions of propulsion system type, aerodynamic lift and flight trajectory to the efficiency with which payloads can be placed into low earth orbit. The higher propulsive efficiency of ramjet and scramjet propulsion has the potential of increasing the payload mass ratio significantly. The contributions of turbojet propulsion and aerodynamic lift are less significant. The additional complexity involved in using aerodynamic propulsion and lift requires dealing with a more comprehensive set of design variables than for rocket boosters. The approach taken is to derive a set of sensitivity functions which relate booster performance to the design variables. The problems of optimum mixing of aerodynamic lift with thrust and determining the optimal boost trajectory is treated. The potential payload capacity of a horizontal take-off air-breathing boost vehicle is examined. The optimization problem which considers propulsive efficiency, aerodynamic configuration, and control and guidance issues is discussed.

  1. Propulsion System Dynamic Modeling of the NASA Supersonic Concept Vehicle for AeroPropulsoServoElasticity

    NASA Technical Reports Server (NTRS)

    Kopasakis, George; Connolly, Joseph W.; Seiel, Jonathan

    2016-01-01

    A summary of the propulsion system modeling under NASA's High Speed Project (HSP) AeroPropulsoServoElasticity (APSE) task is provided with a focus on the propulsion system for the low-boom supersonic configuration developed by Lockheed Martin and referred to as the N+2 configuration. This summary includes details on the effort to date to develop computational models for the various propulsion system components. The objective of this paper is to summarize the model development effort in this task, while providing more detail in the modeling areas that have not been previously published. The purpose of the propulsion system modeling and the overall APSE effort is to develop an integrated dynamic vehicle model to conduct appropriate unsteady analysis of supersonic vehicle performance. This integrated APSE system model concept includes the propulsion system model, and the vehicle structural aerodynamics model. The development to date of such a preliminary integrated model will also be summarized in this report

  2. Propulsion System Dynamic Modeling of the NASA Supersonic Concept Vehicle for AeroPropulsoServoElasticity

    NASA Technical Reports Server (NTRS)

    Kopasakis, George; Connolly, Joseph W.; Seidel, Jonathan

    2014-01-01

    A summary of the propulsion system modeling under NASA's High Speed Project (HSP) AeroPropulsoServoElasticity (APSE) task is provided with a focus on the propulsion system for the lowboom supersonic configuration developed by Lockheed Martin and referred to as the N+2 configuration. This summary includes details on the effort to date to develop computational models for the various propulsion system components. The objective of this paper is to summarize the model development effort in this task, while providing more detail in the modeling areas that have not been previously published. The purpose of the propulsion system modeling and the overall APSE effort is to develop an integrated dynamic vehicle model to conduct appropriate unsteady analysis of supersonic vehicle performance. This integrated APSE system model concept includes the propulsion system model, and the vehicle structural-aerodynamics model. The development to date of such a preliminary integrated model will also be summarized in this report.

  3. Unified Multi-speed analysis (UMA) for the condition monitoring of aero-engines

    NASA Astrophysics Data System (ADS)

    Nembhard, Adrian D.; Sinha, Jyoti K.

    2015-12-01

    For rotating machinery in which speeds and dynamics constantly change, performing vibration-based condition monitoring can be challenging. Thus, an effort is made here to develop a Unified Multi-speed fault diagnosis technique that can exploit useful vibration information available at various speeds from a rotating machine in a single analysis. Commonly applied indicators are computed from data collected from a rig at different speeds for a baseline case and different faults. Four separate analyses are performed: single speed at a single bearing, integrated features from multiple speeds at a single bearing, single speed for integrated features from multiple bearings and the proposed Unified Multi-speed analysis. The Unified Multi-speed approach produces the most conspicuous separation and isolation among the conditions tested. Observations made here suggest integration of more dynamic features available at different speeds improves the learning process of the tool which could prove useful for aero-engine condition monitoring.

  4. A near optimal guidance algorithm for aero-assisted orbit transfer

    NASA Astrophysics Data System (ADS)

    Calise, Anthony J.; Bae, Gyoung H.

    The paper presents a near optimal guidance algorithm for aero-assited orbit plane change, based on minimizing the energy loss during the atmospheric portion of the maneuver. The guidance algorithm makes use of recent results obtained from energy state approximations and singular perturbation analysis of optimal heading change for a hypersonic gliding vehicle. This earlier work ignored the terminal constraint on altitude needed to insure that the vehicle exits that atmosphere. Thus, the resulting guidance algorithm was only appropriate for maneuvering reentry vehicle guidance. In the context of singular perturbation theory, a constraint on final altitude gives rise to a difficult terminal boundary layer problem, which cannot be solved in closed form. This paper will demonstrate the near optimality of a predictive/corrective guidance algorithm for the terminal maneuver. Comparisons are made to numerically optimized trajectories for a range or orbit plane angles.

  5. A near optimal guidance algorithm for aero-assisted orbit transfer

    NASA Technical Reports Server (NTRS)

    Calise, Anthony J.; Bae, Gyoung H.

    1988-01-01

    The paper presents a near optimal guidance algorithm for aero-assited orbit plane change, based on minimizing the energy loss during the atmospheric portion of the maneuver. The guidance algorithm makes use of recent results obtained from energy state approximations and singular perturbation analysis of optimal heading change for a hypersonic gliding vehicle. This earlier work ignored the terminal constraint on altitude needed to insure that the vehicle exits that atmosphere. Thus, the resulting guidance algorithm was only appropriate for maneuvering reentry vehicle guidance. In the context of singular perturbation theory, a constraint on final altitude gives rise to a difficult terminal boundary layer problem, which cannot be solved in closed form. This paper will demonstrate the near optimality of a predictive/corrective guidance algorithm for the terminal maneuver. Comparisons are made to numerically optimized trajectories for a range or orbit plane angles.

  6. User's manual for UCAP: Unified Counter-Rotation Aero-Acoustics Program

    NASA Technical Reports Server (NTRS)

    Culver, E. M.; Mccolgan, C. J.

    1993-01-01

    This is the user's manual for the Unified Counter-rotation Aeroacoustics Program (UCAP), the counter-rotation derivative of the UAAP (Unified Aero-Acoustic Program). The purpose of this program is to predict steady and unsteady air loading on the blades and the noise produced by a counter-rotation Prop-Fan. The aerodynamic method is based on linear potential theory with corrections for nonlinearity associated with axial flux induction, vortex lift on the blades, and rotor-to-rotor interference. The theory for acoustics and the theory for individual blade loading and wakes are derived in Unified Aeroacoustics Analysis for High Speed Turboprop Aerodynamics and Noise, Volume 1 (NASA CR-4329). This user's manual also includes a brief explanation of the theory used for the modelling of counter-rotation.

  7. Numerical Study of a Fuel Centrifugal Pump with Variable Impeller Width for Aero-engines

    NASA Astrophysics Data System (ADS)

    Wang, Bin; Guan, Huasheng; Ye, Zhifeng

    2015-12-01

    As typical pump with large flow rate and high reliability, centrifugal pumps in fuel system of aero-engines mostly regulate flow rate by flow bypass, which leads to low efficiency and large fuel temperature rise especially at low flow rate. An innovative fuel centrifugal pump with variable impeller width is a more effective way to regulate flow rate than flow bypass. To find external characteristics of the centrifugal pump with variable impeller width proposed in this paper, flow domain within the pump is simulated numerically and some primary performance parameters and their correlation are analyzed. Results show that flow rate of the pump can be regulated by variable impeller width and that efficiency for this scheme is higher than that for flow bypass. The higher outlet static pressure the pump runs at, the wider range of flow rates can be obtained with stronger nonlinear relationship between flow rate and impeller width.

  8. A Modular Aero-Propulsion System Simulation of a Large Commercial Aircraft Engine

    NASA Technical Reports Server (NTRS)

    DeCastro, Jonathan A.; Litt, Jonathan S.; Frederick, Dean K.

    2008-01-01

    A simulation of a commercial engine has been developed in a graphical environment to meet the increasing need across the controls and health management community for a common research and development platform. This paper describes the Commercial Modular Aero Propulsion System Simulation (C-MAPSS), which is representative of a 90,000-lb thrust class two spool, high bypass ratio commercial turbofan engine. A control law resembling the state-of-the-art on board modern aircraft engines is included, consisting of a fan-speed control loop supplemented by relevant engine limit protection regulator loops. The objective of this paper is to provide a top-down overview of the complete engine simulation package.

  9. Aero-acoustic performance comparison of core engine noise suppressors on NASA quiet engine C

    NASA Technical Reports Server (NTRS)

    Bloomer, H. E.; Schaefer, J. W.

    1977-01-01

    The relative aero-acoustic effectiveness of two core engine suppressors, a contractor-designed suppressor delivered with the Quiet Engine, and a NASA-designed suppressor was evaluated. The NASA suppressor was tested with and without a splitter making a total of three configurations being reported in addition to the baseline hardwall case. The aerodynamic results are presented in terms of tailpipe pressure loss, corrected net thrust, and corrected specific fuel consumption as functions of engine power setting. The acoustic results are divided into duct and far-field acoustic data. The NASA-designed core suppressor did the better job of suppressing aft end noise, but the splitter associated with it caused a significant engine performance penality. The NASA core suppressor without the spltter suppressed most of the core noise without any engine performance penalty.

  10. An AeroCom Assessment of Black Carbon in Arctic Snow and Sea Ice

    NASA Technical Reports Server (NTRS)

    Jiao, C.; Flanner, M. G.; Balkanski, Y.; Bauer, S. E.; Bellouin, N.; Bernsten, T. K.; Bian, H.; Carslaw, K. S.; Chin, M.; DeLuca, N.; Diehl, T.; Ghan, S. J.; Iversen, T.; Kirkevag, A.; Koch, D.; Liu, X.; Mann, G. W.; Penner, J. E.; Pitari, G.; Schulz, M.; Seland, O; Skeie, R. B.; Steenrod, S. D.; Stier, P.; Tkemura, T.

    2014-01-01

    Though many global aerosols models prognose surface deposition, only a few models have been used to directly simulate the radiative effect from black carbon (BC) deposition to snow and sea ice. Here, we apply aerosol deposition fields from 25 models contributing to two phases of the Aerosol Comparisons between Observations and Models (AeroCom) project to simulate and evaluate within-snow BC concentrations and radiative effect in the Arctic. We accomplish this by driving the offline land and sea ice components of the Community Earth System Model with different deposition fields and meteorological conditions from 2004 to 2009, during which an extensive field campaign of BC measurements in Arctic snow occurred. We find that models generally underestimate BC concentrations in snow in northern Russia and Norway, while overestimating BC amounts elsewhere in the Arctic. Although simulated BC distributions in snow are poorly correlated with measurements, mean values are reasonable. The multi-model mean (range) bias in BC concentrations, sampled over the same grid cells, snow depths, and months of measurements, are -4.4 (-13.2 to +10.7) ng/g for an earlier phase of AeroCom models (phase I), and +4.1 (-13.0 to +21.4) ng/g for a more recent phase of AeroCom models (phase II), compared to the observational mean of 19.2 ng/g. Factors determining model BC concentrations in Arctic snow include Arctic BC emissions, transport of extra-Arctic aerosols, precipitation, deposition efficiency of aerosols within the Arctic, and meltwater removal of particles in snow. Sensitivity studies show that the model-measurement evaluation is only weakly affected by meltwater scavenging efficiency because most measurements were conducted in non-melting snow. The Arctic (60-90degN) atmospheric residence time for BC in phase II models ranges from 3.7 to 23.2 days, implying large inter-model variation in local BC deposition efficiency. Combined with the fact that most Arctic BC deposition originates

  11. Aero-acoustic performance comparison of core engine noise suppressors on NASA quiet engine 'C'

    NASA Technical Reports Server (NTRS)

    Bloomer, H. E.; Schaefer, J. W.

    1977-01-01

    The purpose of the experimental program reported herein was to evaluate and compare the relative aero-acoustic effectiveness of two core engine suppressors, a contractor-designed suppressor delivered with the Quiet Engine, and a NASA-designed suppressor, designed and built subsequently. The NASA suppressor was tested with and without a splitter making a total of three configurations being reported in addition to the baseline hardwall case. The aerodynamic results are presented in terms of tailpipe pressure loss, corrected net thrust, and corrected specific fuel consumption as functions of engine power setting. The acoustic results are divided into duct and far-field acoustic data. The NASA-designed core suppressor did the better job of suppressing aft end noise, but the splitter associated with it caused a significant engine performance penalty. The NASA core suppressor without the splitter suppressed most of the core noise without any engine performance penalty.

  12. A Summary of the Slush Hydrogen Technology Program for the National Aero-Space Plane

    NASA Technical Reports Server (NTRS)

    Mcnelis, Nancy B.; Hardy, Terry L.; Whalen, Margaret V.; Kudlac, Maureen T.; Moran, Matthew E.; Tomsik, Thomas M.; Haberbusch, Mark S.

    1995-01-01

    Slush hydrogen, a mixture of solid and liquid hydrogen, offers advantages of higher density (16 percent) and higher heat capacity (18 percent) than normal boiling point hydrogen. The combination of increased density and heat capacity of slush hydrogen provided a potential to decrease the gross takeoff weight of the National Aero-Space Plane (NASP) and therefore slush hydrogen was selected as the propellant. However, no large-scale data was available on the production, transfer and tank pressure control characteristics required to use slush hydrogen as a fuel. Extensive testing has been performed at the NASA Lewis Research Center K-Site and Small Scale Hydrogen Test Facility between 1990 and the present to provide a database for the use of slush hydrogen. This paper summarizes the results of this testing.

  13. Aero-Structural Optimization of HSCT Configurations in Transonic and Supersonic Flow

    NASA Technical Reports Server (NTRS)

    Alonso, Juan J.

    1999-01-01

    This document outlines the progress made under NASA Cooperative Research Agreement NCC2- 5226 for the period 10/01/97-09/30/98. The work statement originally proposed was meant to extend over the period of two complete years of which only one was funded. Consequently, only a portion of the goals were achieved. Similar work will continue in our group under different sponsorship and will be available in the form of conference and journal publications. The following sections summarize the technical accomplishments obtained during the last year. Details of these accomplishments can be found in the accompanying paper that was presented at the AIAA 37th Aerospace Sciences and Exhibit Meeting which was held in Reno, NV in January of this year. The original proposal outlined a research program meant to lay down the foundation for the development of high-fidelity, fully-coupled aerodynamic/structural optimization methods applicable to a variety of aerospace applications including the design optimization of High Speed Civil Transport (HSCT) configurations. The necessary research and development work was divided into two main efforts which addressed the necessities of the long term goal. Initially, our experience in the simulation of unsteady aeroelastic flows was directly applied to existing aerodynamic optimization techniques in order to provide insight into the effects of aeroelastic deformations on the performance of aircraft which have been designed based on purely aerodynamic cost functions. The intention was to follow up this work with a detailed investigation into the basic research work that has to be completed for the development of an optimization framework which efficiently allows the truly coupled design of aero-structural systems. This follow-up effort was not funded. The outcome of our efforts during the past year was the development of a coupled aero-structural analysis and design environment that was applied to the design of a complete aircraft configuration.

  14. Common aero vehicle autonomous reentry trajectory optimization satisfying waypoint and no-fly zone constraints

    NASA Astrophysics Data System (ADS)

    Jorris, Timothy R.

    2007-12-01

    To support the Air Force's Global Reach concept, a Common Aero Vehicle is being designed to support the Global Strike mission. "Waypoints" are specified for reconnaissance or multiple payload deployments and "no-fly zones" are specified for geopolitical restrictions or threat avoidance. Due to time critical targets and multiple scenario analysis, an autonomous solution is preferred over a time-intensive, manually iterative one. Thus, a real-time or near real-time autonomous trajectory optimization technique is presented to minimize the flight time, satisfy terminal and intermediate constraints, and remain within the specified vehicle heating and control limitations. This research uses the Hypersonic Cruise Vehicle (HCV) as a simplified two-dimensional platform to compare multiple solution techniques. The solution techniques include a unique geometric approach developed herein, a derived analytical dynamic optimization technique, and a rapidly emerging collocation numerical approach. This up-and-coming numerical technique is a direct solution method involving discretization then dualization, with pseudospectral methods and nonlinear programming used to converge to the optimal solution. This numerical approach is applied to the Common Aero Vehicle (CAV) as the test platform for the full three-dimensional reentry trajectory optimization problem. The culmination of this research is the verification of the optimality of this proposed numerical technique, as shown for both the two-dimensional and three-dimensional models. Additionally, user implementation strategies are presented to improve accuracy and enhance solution convergence. Thus, the contributions of this research are the geometric approach, the user implementation strategies, and the determination and verification of a numerical solution technique for the optimal reentry trajectory problem that minimizes time to target while satisfying vehicle dynamics and control limitation, and heating, waypoint, and no

  15. 77 FR 26022 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ..., AR 72209-7056, 501-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center...-5295/800-950-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology Laboratory, 1..., Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory). Pacific Toxicology Laboratories,...

  16. 76 FR 54477 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... 72209-7056, 501-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical...-5295/800-950-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology Laboratory, 1..., Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory). Pacific Toxicology Laboratories,...

  17. Blood collection tubes as medical devices: The potential to affect assays and proposed verification and validation processes for the clinical laboratory.

    PubMed

    Bowen, Raffick A R; Adcock, Dorothy M

    2016-12-01

    Blood collection tubes (BCTs) are an often under-recognized variable in the preanalytical phase of clinical laboratory testing. Unfortunately, even the best-designed and manufactured BCTs may not work well in all clinical settings. Clinical laboratories, in collaboration with healthcare providers, should carefully evaluate BCTs prior to putting them into clinical use to determine their limitations and ensure that patients are not placed at risk because of inaccuracies due to poor tube performance. Selection of the best BCTs can be achieved through comparing advertising materials, reviewing the literature, observing the device at a scientific meeting, receiving a demonstration, evaluating the device under simulated conditions, or testing the device with patient samples. Although many publications have discussed method validations, few detail how to perform experiments for tube verification and validation. This article highlights the most common and impactful variables related to BCTs and discusses the validation studies that a typical clinical laboratory should perform when selecting BCTs. We also present a brief review of how in vitro diagnostic devices, particularly BCTs, are regulated in the United States, the European Union, and Canada. The verification and validation of BCTs will help to avoid the economic and human costs associated with incorrect test results, including poor patient care, unnecessary testing, and delays in test results. We urge laboratorians, tube manufacturers, diagnostic companies, and other researchers to take all the necessary steps to protect against the adverse effects of BCT components and their additives on clinical assays.

  18. Ototoxic Medications (Medication Effects)

    MedlinePlus

    ... Information for the Public / Hearing and Balance Ototoxic Medications (Medication Effects) By Barbara Cone, Patricia Dorn, Dawn Konrad- ... Audiology Information Series [PDF]. What Is Ototoxicity? Certain medications can damage the ear, resulting in hearing loss, ...

  19. C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 2: Test Bed Performance Evaluation and Final AeroMACS Recommendations

    NASA Technical Reports Server (NTRS)

    Hall, Edward; Magner, James

    2011-01-01

    This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II (this document) describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

  20. C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 1: Concepts of Use, Initial System Requirements, Architecture, and AeroMACS Design Considerations

    NASA Technical Reports Server (NTRS)

    Hall, Edward; Isaacs, James; Henriksen, Steve; Zelkin, Natalie

    2011-01-01

    This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I (this document) is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

  1. American College of Medical Genetics and Genomics Standards and Guidelines for Clinical Genetics Laboratories, 2014 edition: technical standards and guidelines for Huntington disease.

    PubMed

    Bean, Lora; Bayrak-Toydemir, Pinar

    2014-12-01

    Huntington disease is an autosomal-dominant neurodegenerative disease of mid-life onset caused by expansion of a polymorphic trinucleotide (CAG) repeat. Variable penetrance for alleles carrying 36-39 repeats has been noted, but the disease appears fully penetrant when the repeat numbers are >40. An abnormal CAG repeat may expand, contract, or be stably transmitted when passed from parent to child. Assays used to diagnose Huntington disease must be optimized to ensure the accurate and unambiguous quantitation of CAG repeat length. This document provides an overview of Huntington disease and methodological considerations for Huntington disease testing. Examples of laboratory reports are also included.

  2. Comparative evaluation of active learning and the traditional lectures in physiology: a case study of 200 level medical laboratory students of Imo State Unversity, Owerri.

    PubMed

    Anyaehie, U S B; Nwobodo, Ed; Njoku, C J; Inah, G A

    2007-01-01

    Currently, understanding of physiology and disease patterns is undergoing a fundamental paradigm shift with attendant shift in education of health professionals worldwide towards active learning to encourage exploration of connections and their relationships. We introduced problem-based learning to physiology teaching of medial laboratory students to confirm worldwide reports that active learning environments offer better learning opportunities over the traditional methods which is the predominant teaching method in Nigerian universities. Our findings indicate that problem-based learning increases students' attendance/participation in classes and performance in examination. We recommend the integration of active learning into physiology curriculum of Nigerian Universities.

  3. Laboratory reengineering facilitates cost management.

    PubMed

    Ellis, J E; Moser, L H

    1998-08-01

    In 1993, The Medical University of South Carolina (MUSC) in Charleston undertook a change management initiative to achieve a more cost-competitive position in its market and become a more attractive partner for a possible future affiliation with another provider organization. A key element of this change process was a reorganization of the medical center's laboratory department. Through consolidation of MUSC's separate laboratories and the introduction of a new, more efficient chemistry analyzer system, the medical center realized annual laboratory savings of approximately $1.3 million.

  4. CONSIDERATIONS ON ANATOMY AND PHYSIOLOGY OF LYMPH VESSELS OF UPPER AERO DIGESTIVE ORGANS AND CERVICAL SATELLITE LYMPH NODE GROUP.

    PubMed

    Ciupilan, Corina; Stan, C I

    2016-01-01

    The almost constant local regional development of the cancers of upper aero digestive organs requires the same special attention to cervical lymph node metastases, as well as to the primary neoplastic burning point. The surgical therapy alone or associated has a mutilating, damaging character, resulting in loss of an organ and function, most of the times with social implications, involving physical distortions with aesthetic consequences, which make the reintegration of the individual into society questionable. The problem of cervical lymph node metastases is vast and complex, reason why we approached several anatomical and physiological aspects of lymph vessels of the aero digestive organs. Among the available elements during treatment, the headquarters of the tumour, its histologic degree, and its infiltrative nature, each of them significantly influences the possibility of developing metastases.

  5. National Emissions Report (1978): National Emissions Data Systems (NEDS) of the Aerometric and Emissions Reporting System (AEROS). Annual report

    SciTech Connect

    Not Available

    1980-12-01

    The National Emissions Report summarizes annual cumulative estimates of source emissions of five criteria pollutants: particulates, sulfur oxides, nitrogen oxides, hydrocarbons, and carbon monoxide. Source emissions data are reported to the U. S. Environmental Protection Agency under provisions of Section 110 of the Clean Air Act, as amended 1977, and EPA Regulations, Title 40, Code of Federal Regulations, Part 51.321. Summary data are presented for the nation as a whole, for individual states, and for Air Quality Control Regions and individual interstate portions thereof. The data compilations result from the operations of the National Emissions Data System (NEDS), which functions as a component of the comprehensive EPA air information system--the Aerometric and Emissions Reporting System (AEROS). AEROS is managed by the National Air Data Branch, Monitoring and Data Analysis Division, Office of Air Quality Planning and Standards, U. S. Environmental Protection Agency at Research Triangle Park, North Carolina 27711.

  6. National emissions report (1979): National Emissions Data Systems (NEDS) of the Aerometric and Emissions Reporting System (AEROS). Annual report

    SciTech Connect

    Not Available

    1981-08-01

    The National Emissions Report summarizes annual cumulative estimates of source emissions of five criteria pollutants: particulates, sulfur oxides, nitrogen oxides, hydrocarbons, and carbon monoxide. Source emissions data are reported to the U. S. Environmental Protection Agency under provisions of Section 110 of the Clean Air Act, as amended 1977, and EPA Regulations, Title 40, Code of Federal Regulations, Part 51.321. Summary data are presented for the nation as a whole, for individual states, and for Air Quality Control Regions and individual interstate portions thereof. The data compilations result from the operations of the National Emissions Data System (NEDS), which functions as a component of the comprehensive EPA air information system--the Aerometric and Emissions Reporting System (AEROS). AEROS is managed by the National Air Data Branch, Monitoring and Data Analysis Division, Office of Air Quality Planning and Standards, U. S. Environmental Protection Agency at Research Triangle Park, North Carolina 27711.

  7. National emissions report, 1985: National Emissions Data Systems (NEDS) of the Aerometric and Emissions Reporting System (AEROS). Final report

    SciTech Connect

    Not Available

    1988-09-01

    The National Emissions Report summarizes annual cumulative estimates of source emissions of five criteria pollutants: particulates, sulfur oxides, nitrogen oxides, volatile organic compounds, and carbon monoxide. Source emissions data are reported to the U.S. Environmental Protection Agency under provisions of Section 110 of the Clean Air Act, as amended 1977, and EPA regulations, Title 40, Code of Federal Regulations, Part 51.321. Summary data are presented for the Nation as a whole, for individual States, and for Air Quality Control Regions and for individual interstate portions thereof. The data compilations result from the operations of the National Emissions Data System (NED), which functions as a component of the comprehensive EPA air information system--the Aerometric and Emissions Reporting System (AEROS). AEROS is managed by the National Air Data Branch, Emissions Standard Division, Office of Air Quality Planning and Standards, U.S. Environmental Protection Agency, at Research Triangle Park, North Carolina.

  8. National Emissions Report, 1983: national emissions data systems (neds) of the Aerometric and Emissions Reporting System (AEROS). Final report

    SciTech Connect

    Not Available

    1985-12-01

    The National Emissions Report summarizes annual cumulative estimates of source emissions of five criteria pollutants: particulates, sulfur oxides, nitrogen oxides, volatile organic compounds, and carbon monoxide. Source emissions data are reported to the U.S. Environmental Protection Agency under provisions of Section 110 of the Clean Air Act, as amended 1977, and EPA Regulations, Title 40, Code of Federal Regulations, Part 51.321. Summary data are presented for the Nation as a whole, for individual States, and for Air Quality Control Regions and for individual interstate portions thereof. The data compilations result from the operations of the National Emissions Data System (NEDS), which functions as a component of the comprehensive EPA air information system--the Aerometric and Emissions Reporting System (AEROS). AEROS is managed by the National Air Data Branch, Monitoring and Data Analysis Division, Office of Air Quality Planning and Standards, U.S. Environmental Protection Agency at Research Triangle Park, North Carolina 27711.

  9. Standards for laboratory accreditation.

    PubMed

    1982-12-01

    After years of review by all of the CAP resource and other committees and councils, the Commission on Laboratory Accreditation developed a revised Standards for Accreditation of Medical Laboratories (Last revision, 1974). They were approved by the House of Delegates and, in the February issue of Pathologist '82, comments were solicited from the entire membership. Presented in the following pages are the final Standards for Laboratory Accreditation, which the Board of Governors adopted as CAP policy at its Sept. 2-4 meeting in Traverse City, Mich.

  10. The proton and carbon therapy experience of the medical physics group at the Italian Southern Laboratories: Monte Carlo simulation and experiment

    NASA Astrophysics Data System (ADS)

    Cirrone, G. A. Pablo; Agodi, C.; Candiano, G.; Cuttone, G.; di Rosa, F.; Mongelli, E.; Lojacono, P.; Mazzaglia, S.; Russo, G.; Romano, F.; Valastro, L. M.; Lo Nigro, S.; Pittera, S.; Sabini, M. G.; Rafaele, L.; Salamone, V.; Morone, C.; Randazzo, N.; Sipala, V.; Bucciolini, M.; Bruzzi, M.; Menichelli, D.

    2008-03-01

    At the Italian Southern Laboratories (LNS) of the Italian National Institute for Nuclear Physics the first, and actually unique, Italian proton therapy center is installed and operating. Up to now, 140 patients have been treated. In this environment a big effort is devoted towards Monte Carlo simulation expeciallt with the GEANT4 Toolkit. The authors of this work belong to the Geant4 Collaboration and they use the toolkit in their research programs. They maintain a Monte Carlo application devoted to the complete simulation of a generic hadron-therapy beam line and take active part in the study of fragmentation processes. Moreover they are working in the development of a prototype of a proton Computed tomographic system. In this work we will report our results in the field of proton and carbon therapy either in the simulation as well in the experimental side of our activity.

  11. Status report from the American Acne & Rosacea Society on medical management of acne in adult women, part 1: overview, clinical characteristics, and laboratory evaluation.

    PubMed

    Del Rosso, James Q; Harper, Julie C; Graber, Emmy M; Thiboutot, Diane; Silverberg, Nanette B; Eichenfield, Dawn Zhang; Eichenfield, Lawrence F

    2015-10-01

    Acne presenting in adult women is commonly encountered in clinical practice. Many affected women have had acne during their teenaged years, have tried several therapies in the past, and are seeking effective treatment. Others are frustrated by the inexplicable emergence of acne as an adult when they never had it as a teenager. Both groups seek an explanation of why they have acne, are often psychosocially affected by its effects on appearance and self-esteem, and all are wanting effective and safe treatment. Clinicians are encouraged to connect favorably with each patient through careful history and physical examination and to consider underlying causes of androgen excess. Practical approaches to examination and laboratory evaluation are discussed.

  12. Nanotechnology for photodynamic therapy: a perspective from the Laboratory of Dr. Michael R. Hamblin in the Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School.

    PubMed

    Hamblin, Michael R; Chiang, Long Y; Lakshmanan, Shanmugamurthy; Huang, Ying-Ying; Garcia-Diaz, Maria; Karimi, Mahdi; de Souza Rastelli, Alessandra Nara; Chandran, Rakkiyappan

    2015-08-01

    The research interests of the Hamblin Laboratory are broadly centered on the use of different kinds of light to treat many different diseases. Photodynamic therapy (PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria, cancer cells and destroy unwanted tissue. Likewise, UV light is also good at killing especially pathogens. By contrast, red or near-infrared light can have the opposite effect, to act to preserve tissue from dying and can stimulate healing and regeneration. In all these applications, nanotechnology is having an ever-growing impact. In PDT, self-assembled nano-drug carriers (micelles, liposomes, etc.) play a great role in solubilizing the photosensitizers, metal nanoparticles can carry out plasmon resonance enhancement, and fullerenes can act as photosensitizers, themselves. In the realm of healing, single-walled carbon nanotubes can be electrofocused to produce nano-electonic biomedical devices, and nanomaterials will play a great role in restorative dentistry.

  13. Nanotechnology for photodynamic therapy: a perspective from the Laboratory of Dr. Michael R. Hamblin in the Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School

    PubMed Central

    Hamblin, Michael R.; Chiang, Long Y.; Lakshmanan, Shanmugamurthy; Huang, Ying-Ying; Garcia-Diaz, Maria; Karimi, Mahdi; de Souza Rastelli, Alessandra Nara; Chandran, Rakkiyappan

    2015-01-01

    The research interests of the Hamblin Laboratory are broadly centered on the use of different kinds of light to treat many different diseases. Photodynamic therapy (PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria, cancer cells and destroy unwanted tissue. Likewise, UV light is also good at killing especially pathogens. By contrast, red or near-infrared light can have the opposite effect, to act to preserve tissue from dying and can stimulate healing and regeneration. In all these applications, nanotechnology is having an ever-growing impact. In PDT, self-assembled nano-drug carriers (micelles, liposomes, etc.) play a great role in solubilizing the photosensitizers, metal nanoparticles can carry out plasmon resonance enhancement, and fullerenes can act as photosensitizers, themselves. In the realm of healing, single-walled carbon nanotubes can be electrofocused to produce nano-electonic biomedical devices, and nanomaterials will play a great role in restorative dentistry. PMID:26640747

  14. Numerical prediction of the spatial and temporal characteristics of the aero-optical disturbance produced by a helicopter in hover

    NASA Astrophysics Data System (ADS)

    Kelly, Ryan T.

    Aero-optical disturbances produced from turbulent compressible flow-fields can seriously degrade the performance of an optical signal. At compressible flight speeds these disturbances stem from the density variations present in turbulent boundary layers and free shear layers; however helicopters typically operate at incompressible speeds, which nearly eliminates the aberrating effect of these flows. For helicopter platforms the sources of aberration originate from the high subsonic flow-field near the rotor blade tips in the form of rotor-tip vortices and from the high temperatures of the engine effluence. During hover the shed rotor-tip vortices and engine effluence convect with the rotor wake encircling the airframe and subsequently a helicopter mounted optical system. The aero-optical effects of the wake beneath a hovering helicopter were analyzed using a combination of Unsteady RANS (URANS) and Large-Eddy Simulations (LES). The spatial and temporal characteristics of the numerical optical wavefronts were compared to full-scale aero-optic experimental measurements. The results indicate that the turbulence of the rotor-tip vortices contributes to the higher order aberrations measured experimentally and that the thermal exhaust plumes effectively limit the optical field-of-regard to forward- and side-looking beam directions. This information along with the computed optical aberrations of the wake can be used to guide the development of adaptive-optic systems or other beam-control approaches.

  15. Turbofan Volume Dynamics Model for Investigations of Aero-Propulso-Servo-Elastic Effects in a Supersonic Commercial Transport

    NASA Technical Reports Server (NTRS)

    Connolly, Joseph W.; Kopasakis, George; Lemon, Kimberly A.

    2010-01-01

    A turbofan simulation has been developed for use in aero-propulso-servo-elastic coupling studies, on supersonic vehicles. A one-dimensional lumped volume approach is used whereby each component (fan, high-pressure compressor, combustor, etc.) is represented as a single volume using characteristic performance maps and conservation equations for continuity, momentum and energy. The simulation is developed in the MATLAB/SIMULINK (The MathWorks, Inc.) environment in order to facilitate controls development, and ease of integration with a future aero-servo-elastic vehicle model being developed at NASA Langley. The complete simulation demonstrated steady state results that closely match a proposed engine suitable for a supersonic business jet at the cruise condition. Preliminary investigation of the transient simulation revealed expected trends for fuel flow disturbances as well as upstream pressure disturbances. A framework for system identification enables development of linear models for controller design. Utilizing this framework, a transfer function modeling an upstream pressure disturbance s impacts on the engine speed is developed as an illustrative case of the system identification. This work will eventually enable an overall vehicle aero-propulso-servo-elastic model

  16. Integrated approach for stress based lifing of aero gas turbine blades

    NASA Astrophysics Data System (ADS)

    Abu, Abdullahi Obonyegba

    In order to analyse the turbine blade life, the damage due to the combined thermal and mechanical loads should be adequately accounted for. This is more challenging when detailed component geometry is limited. Therefore, a compromise between the level of geometric detail and the complexity of the lifing method to be implemented would be necessary. This research focuses on how the life assessment of aero engine turbine blades can be done, considering the balance between available design inputs and adequate level of fidelity. Accordingly, the thesis contributes to developing a generic turbine blade lifing method that is based on the engine thermodynamic cycle; as well as integrating critical design/technological factors and operational parameters that influence the aero engine blade life. To this end, thermo-mechanical fatigue was identified as the critical damage phenomenon driving the life of the turbine blade.. The developed approach integrates software tools and numerical models created using the minimum design information typically available at the early design stages. Using finite element analysis of an idealised blade geometry, the approach captures relevant impacts of thermal gradients and thermal stresses that contribute to the thermo-mechanical fatigue damage on the gas turbine blade. The blade life is evaluated using the Neu/Sehitoglu thermo-mechanical fatigue model that considers damage accumulation due to fatigue, oxidation, and creep. The leading edge is examined as a critical part of the blade to estimate the damage severity for different design factors and operational parameters. The outputs of the research can be used to better understand how the environment and the operating conditions of the aircraft affect the blade life consumption and therefore what is the impact on the maintenance cost and the availability of the propulsion system. This research also finds that the environmental (oxidation) effect drives the blade life and the blade coolant

  17. Aero-Optical Turbulent Boundary Layer/Shear Layer Experiment On The KC-135 Aircraft Revisited

    NASA Astrophysics Data System (ADS)

    Craig, James E.; Allen, C.

    1985-06-01

    This paper examines the aero-optical effects associated with propagating a laser beam through both an aircraft turbulent boundary layer and artificially generated shear layers. The data present comparisons of observed optical performances with those inferred from aerodynamic measurements of unsteady density and correlation lengths within the same random flow fields. Using optical instrumentation with tens of microseconds temporal resolution through a finite aperture, optical performance degradation was determined and contrasted with the infinite-aperture, time-averaged aerodynamic measurement. In addition, the optical data were artificially clipped to compare to theoretical scaling calculations. Optical instrumentation consisted of a custom Q-switched Nd:YAG double-pulsed laser and a holographic camera that recorded the random flow field in a double-pass, double-pulse mode. Aero-dynamic parameters were measured using hot film anemometer probes and a five-hole pressure probe. Each technique is described with its associated theo-retical basis for comparison. The effects of finite aperture and spatial and temporal frequencies of the random flow are considered. The results presented represent five flights flown at altitudes from 1.8 km to 10.7 km and at Mach numbers from 0.32 to 0.79. Single-pass phase deviations for the boundary layer were from 0.06 to 0.17 waves (at X = 0.53 ;Am) with piston and tilt components removed. Measured phase deviations for the artificially induced shear flows were from 0.10 to 0.279 waves (at X = 0.53 /um) with piston and tilt components removed. However, when low order aberrations through coma were removed, the remaining deviations were only 0.09 to 0.18 waves. This resulted in a 33 to 250% increase in the Strehl ratio at the 14 cm optical aperture. It was further shown that the low order aberrations corresponded to the longer wavelengths in the random flow, and these waves propagated with a longer characteristic time than the higher order

  18. Simulating Laboratory Procedures.

    ERIC Educational Resources Information Center

    Baker, J. E.; And Others

    1986-01-01

    Describes the use of computer assisted instruction in a medical microbiology course. Presents examples of how computer assisted instruction can present case histories in which the laboratory procedures are simulated. Discusses an authoring system used to prepare computer simulations and provides one example of a case history dealing with fractured…

  19. PREFACE: 3rd International Conference on Geological, Geographical, Aerospace and Earth Science 2015 (AeroEarth 2015)

    NASA Astrophysics Data System (ADS)

    Gaol, F. L.

    2016-02-01

    The 3rd International Conferences on Geological, Geographical, Aerospaces and Earth Sciences 2015 (AeroEarth 2015), was held at The DoubleTree Hilton, Jakarta, Indonesia during 26 - 27 September 2015. The 1st AeoroEarth was held succefully in Jakarta in 2013. The success continued to The 2nd AeroEarth 2014 that was held in Kuta Bali, Indonesia. The publications were published by EES IOP in http://iopscience.iop.org/1755-1315/19/1 and http://iopscience.iop.org/1755-1315/23/1 respectively. The AeroEarth 2015 conference aims to bring together researchers, engineers and scientists from around the world. Through research and development, Earth's scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. The theme of AeroEarth 2015 is ''Earth and Aerospace Sciences : Challenges and Opportunities'' Earth provides resources and the exact conditions to make life possible. However, with the advent of technology and industrialization, the Earth's resources are being pushed to the brink of depletion. Non-sustainable industrial practices are not only endangering the supply of the Earth's natural resources, but are also putting burden on life itself by bringing about pollution and climate change. A major role of earth science scholars is to examine the delicate balance between the Earth's resources and the growing demands of industrialization. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program as well as the invited and plenary speakers. This year, we received 78 papers and after rigorous review, 18 papers were accepted. The participants

  20. [Distribution of financial resources according to the productivity (determined by bibliometry) in the Medical Research Laboratories of the Hospital das Clínicas da Faculdade de Medicina da Universidad de São Paulo (Brazil)].

    PubMed

    Montes, G S

    2000-04-01

    A challenge that research managers have to face is how to "reallocate" agency budgets in order to bring them in line with the results of performance reviews. Research policies must develop a strategic plan describing their goals, devise yardsticks to measure their progress, and tie that performance to allocate research funds with some degree of priority. Though Brazil already has a substantial presence in world's science, scientific enterprise must be used to strengthen it. The first step should be to raise standards in Brazilian science by concentrating the resources on supporting excellence. A strategy to judge biomedical research productivity should include tactics to disclose whether the resulting publications have appeared in the field's most respected, peer-reviewed journals. A pilot project to road-test the above-discussed ideas on performance measurements was conducted at the Laboratories of Medical Research (Clinical Hospital, University of São Paulo School of Medicine). These Laboratories perform a vast proportion of biomedical research at the country's largest University. This article illustrates that confidence in fairness and consistency with which funds are now being allocated has helped to improve productivity, thus showing that this strategy is fruitful.

  1. User's Guide for the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS)

    NASA Technical Reports Server (NTRS)

    Frederick, Dean K.; DeCastro, Jonathan A.; Litt, Jonathan S.

    2007-01-01

    This report is a Users Guide for the NASA-developed Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) software, which is a transient simulation of a large commercial turbofan engine (up to 90,000-lb thrust) with a realistic engine control system. The software supports easy access to health, control, and engine parameters through a graphical user interface (GUI). C-MAPSS provides the user with a graphical turbofan engine simulation environment in which advanced algorithms can be implemented and tested. C-MAPSS can run user-specified transient simulations, and it can generate state-space linear models of the nonlinear engine model at an operating point. The code has a number of GUI screens that allow point-and-click operation, and have editable fields for user-specified input. The software includes an atmospheric model which allows simulation of engine operation at altitudes from sea level to 40,000 ft, Mach numbers from 0 to 0.90, and ambient temperatures from -60 to 103 F. The package also includes a power-management system that allows the engine to be operated over a wide range of thrust levels throughout the full range of flight conditions.

  2. Integrated Aero-Propulsion CFD Methodology for the Hyper-X Flight Experiment

    NASA Technical Reports Server (NTRS)

    Cockrell, Charles E., Jr.; Engelund, Walter C.; Bittner, Robert D.; Dilley, Arthur D.; Jentink, Tom N.; Frendi, Abdelkader

    2000-01-01

    Computational fluid dynamics (CFD) tools have been used extensively in the analysis and development of the X-43A Hyper-X Research Vehicle (HXRV). A significant element of this analysis is the prediction of integrated vehicle aero-propulsive performance, which includes an integration of aerodynamic and propulsion flow fields. This paper describes analysis tools used and the methodology for obtaining pre-flight predictions of longitudinal performance increments. The use of higher-fidelity methods to examine flow-field characteristics and scramjet flowpath component performance is also discussed. Limited comparisons with available ground test data are shown to illustrate the approach used to calibrate methods and assess solution accuracy. Inviscid calculations to evaluate lateral-directional stability characteristics are discussed. The methodology behind 3D tip-to-tail calculations is described and the impact of 3D exhaust plume expansion in the afterbody region is illustrated. Finally, future technology development needs in the area of hypersonic propulsion-airframe integration analysis are discussed.

  3. Propulsion System Dynamic Modeling for the NASA Supersonic Concept Vehicle: AeroPropulsoServoElasticity

    NASA Technical Reports Server (NTRS)

    Kopasakis, George; Connolly, Joseph; Seidel, Jonathan

    2014-01-01

    A summary of the propulsion system modeling under NASA's High Speed Project (HSP) AeroPropulsoServoElasticity (APSE) task is provided with a focus on the propulsion system for the low-boom supersonic configuration developed by Lockheed Martin and referred to as the N+2 configuration. This summary includes details on the effort to date to develop computational models for the various propulsion system components. The objective of this paper is to summarize the model development effort in this task, while providing more detail in the modeling areas that have not been previously published. The purpose of the propulsion system modeling and the overall APSE effort is to develop an integrated dynamic vehicle model to conduct appropriate unsteady analysis of supersonic vehicle performance. This integrated APSE system model concept includes the propulsion system model, and the vehicle structural-aerodynamics model. The development to date of such a preliminary integrated model will also be summarized in this report.propulsion system dynamics, the structural dynamics, and aerodynamics.

  4. Rotary-Wing Relevant Compressor Aero Research and Technology Development Activities at Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Welch, Gerard E.; Hathaway, Michael D.; Skoch, Gary J.; Snyder, Christopher A.

    2012-01-01

    Technical challenges of compressors for future rotorcraft engines are driven by engine-level and component-level requirements. Cycle analyses are used to highlight the engine-level challenges for 3000, 7500, and 12000 SHP-class engines, which include retention of performance and stability margin at low corrected flows, and matching compressor type, axial-flow or centrifugal, to the low corrected flows and high temperatures in the aft stages. At the component level: power-to-weight and efficiency requirements impel designs with lower inherent aerodynamic stability margin; and, optimum engine overall pressure ratios lead to small blade heights and the associated challenges of scale, particularly increased clearance-to-span ratios. The technical challenges associated with the aerodynamics of low corrected flows and stability management impel the compressor aero research and development efforts reviewed herein. These activities include development of simple models for clearance sensitivities to improve cycle calculations, full-annulus, unsteady Navier-Stokes simulations used to elucidate stall, its inception, and the physics of stall control by discrete tip-injection, development of an actuator-duct-based model for rapid simulation of nonaxisymmetric flow fields (e.g., due inlet circumferential distortion), advanced centrifugal compressor stage development and experimentation, and application of stall control in a T700 engine.

  5. DSMC aero-thermo-dynamic analysis of a sample-return capsule

    NASA Astrophysics Data System (ADS)

    Zuppardi, Gennaro; Savino, Raffaele; Boffa, Chiara; Carandente, Valerio

    2012-11-01

    A rarefied aero-thermo-dynamic analysis of a sample Earth Return Capsule during the high energy, high altitude re-entry path from an exploration mission is presented. The altitude interval 70-120 km is considered, where the capsule experiences different flow fields. In fact, the flow regime ranges from continuum low density to near free molecular flow and, even though the free stream velocity is almost constant (13 km/s) in the whole altitude interval, the Mach number changes from 44 to 32 and the Reynolds number, based on the capsule diameter, ranges from 4.92×104 to 9. The computations have been carried out using two direct simulation Monte Carlo codes: DS2V to compute local quantities such as heat flux, thermal and aerodynamic loads at zero angle of attack and DS3V to compute global aerodynamic coefficients in the range of the angle of attack 0-60 deg; The results verified that in this altitude interval the heat flux and the thermal load reasonably satisfy specific requirements for the thermal protection system and that the capsule is longitudinally stable up to an angle of attack of about 40 deg..

  6. KC-135 aero-optical turbulent boundary layer/shear layer experiment revisited

    NASA Astrophysics Data System (ADS)

    Craig, J.; Allen, C.

    1987-05-01

    The aero-optical effects associated with propagating a laser beam through both an aircraft turbulent boundary layer and artificially generated shear layers are examined. The data present comparisons from observed optical performance with those inferred from aerodynamic measurements of unsteady density and correlation lengths within the same random flow fields. Using optical instrumentation with tens of microsecond temporal resolution through a finite aperture, optical performance degradation was determined and contrasted with the infinite aperture time averaged aerodynamic measurement. In addition, the optical data were artificially clipped to compare to theoretical scaling calculations. Optical instrumentation consisted of a custom Q switched Nd:Yag double pulsed laser, and a holographic camera which recorded the random flow field in a double pass, double pulse mode. Aerodynamic parameters were measured using hot film anemometer probes and a five hole pressure probe. Each technique is described with its associated theoretical basis for comparison. The effects of finite aperture and spatial and temporal frequencies of the random flow are considered.

  7. KC-135 aero-optical turbulent boundary layer/shear layer experiment revisited

    NASA Technical Reports Server (NTRS)

    Craig, J.; Allen, C.

    1987-01-01

    The aero-optical effects associated with propagating a laser beam through both an aircraft turbulent boundary layer and artificially generated shear layers are examined. The data present comparisons from observed optical performance with those inferred from aerodynamic measurements of unsteady density and correlation lengths within the same random flow fields. Using optical instrumentation with tens of microsecond temporal resolution through a finite aperture, optical performance degradation was determined and contrasted with the infinite aperture time averaged aerodynamic measurement. In addition, the optical data were artificially clipped to compare to theoretical scaling calculations. Optical instrumentation consisted of a custom Q switched Nd:Yag double pulsed laser, and a holographic camera which recorded the random flow field in a double pass, double pulse mode. Aerodynamic parameters were measured using hot film anemometer probes and a five hole pressure probe. Each technique is described with its associated theoretical basis for comparison. The effects of finite aperture and spatial and temporal frequencies of the random flow are considered.

  8. Near-field sound radiation of fan tones from an installed turbofan aero-engine.

    PubMed

    McAlpine, Alan; Gaffney, James; Kingan, Michael J

    2015-09-01

    The development of a distributed source model to predict fan tone noise levels of an installed turbofan aero-engine is reported. The key objective is to examine a canonical problem: how to predict the pressure field due to a distributed source located near an infinite, rigid cylinder. This canonical problem is a simple representation of an installed turbofan, where the distributed source is based on the pressure pattern generated by a spinning duct mode, and the rigid cylinder represents an aircraft fuselage. The radiation of fan tones can be modelled in terms of spinning modes. In this analysis, based on duct modes, theoretical expressions for the near-field acoustic pressures on the cylinder, or at the same locations without the cylinder, have been formulated. Simulations of the near-field acoustic pressures are compared against measurements obtained from a fan rig test. Also, the installation effect is quantified by calculating the difference in the sound pressure levels with and without the adjacent cylindrical fuselage. Results are shown for the blade passing frequency fan tone radiated at a supersonic fan operating condition.

  9. Uncertainty of measurement for large product verification: evaluation of large aero gas turbine engine datums

    NASA Astrophysics Data System (ADS)

    Muelaner, J. E.; Wang, Z.; Keogh, P. S.; Brownell, J.; Fisher, D.

    2016-11-01

    Understanding the uncertainty of dimensional measurements for large products such as aircraft, spacecraft and wind turbines is fundamental to improving efficiency in these products. Much work has been done to ascertain the uncertainty associated with the main types of instruments used, based on laser tracking and photogrammetry, and the propagation of this uncertainty through networked measurements. Unfortunately this is not sufficient to understand the combined uncertainty of industrial measurements, which include secondary tooling and datum structures used to locate the coordinate frame. This paper presents for the first time a complete evaluation of the uncertainty of large scale industrial measurement processes. Generic analysis and design rules are proven through uncertainty evaluation and optimization for the measurement of a large aero gas turbine engine. This shows how the instrument uncertainty can be considered to be negligible. Before optimization the dominant source of uncertainty was the tooling design, after optimization the dominant source was thermal expansion of the engine; meaning that no further improvement can be made without measurement in a temperature controlled environment. These results will have a significant impact on the ability of aircraft and wind turbines to improve efficiency and therefore reduce carbon emissions, as well as the improved reliability of these products.

  10. Nonlocal sparse model with adaptive structural clustering for feature extraction of aero-engine bearings

    NASA Astrophysics Data System (ADS)

    Zhang, Han; Chen, Xuefeng; Du, Zhaohui; Li, Xiang; Yan, Ruqiang

    2016-04-01

    Fault information of aero-engine bearings presents two particular phenomena, i.e., waveform distortion and impulsive feature frequency band dispersion, which leads to a challenging problem for current techniques of bearing fault diagnosis. Moreover, although many progresses of sparse representation theory have been made in feature extraction of fault information, the theory also confronts inevitable performance degradation due to the fact that relatively weak fault information has not sufficiently prominent and sparse representations. Therefore, a novel nonlocal sparse model (coined NLSM) and its algorithm framework has been proposed in this paper, which goes beyond simple sparsity by introducing more intrinsic structures of feature information. This work adequately exploits the underlying prior information that feature information exhibits nonlocal self-similarity through clustering similar signal fragments and stacking them together into groups. Within this framework, the prior information is transformed into a regularization term and a sparse optimization problem, which could be solved through block coordinate descent method (BCD), is formulated. Additionally, the adaptive structural clustering sparse dictionary learning technique, which utilizes k-Nearest-Neighbor (kNN) clustering and principal component analysis (PCA) learning, is adopted to further enable sufficient sparsity of feature information. Moreover, the selection rule of regularization parameter and computational complexity are described in detail. The performance of the proposed framework is evaluated through numerical experiment and its superiority with respect to the state-of-the-art method in the field is demonstrated through the vibration signals of experimental rig of aircraft engine bearings.

  11. Towards an Aero-Propulso-Servo-Elasticity Analysis of a Commercial Supersonic Transport

    NASA Technical Reports Server (NTRS)

    Connolly, Joseph W.; Kopasakis, George; Chwalowski, Pawel; Sanetrik, Mark D.; Carlson, Jan-Renee; Silva, Walt A.; McNamara, Jack

    2016-01-01

    This paper covers the development of an aero-propulso-servo-elastic (APSE) model using computational fluid dynamics (CFD) and linear structural deformations. The APSE model provides the integration of the following two previously developed nonlinear dynamic simulations: a variable cycle turbofan engine and an elastic supersonic commercial transport vehicle. The primary focus of this study is to provide a means to include relevant dynamics of a turbomachinery propulsion system into the aeroelastic studies conducted during a vehicle design, which have historically neglected propulsion effects. A high fidelity CFD tool is used here for the integration platform. The elastic vehicle neglecting the propulsion system serves as a comparison of traditional approaches to the APSE results. An overview of the methodology is presented for integrating the propulsion system and elastic vehicle. Static aeroelastic analysis comparisons between the traditional and developed APSE models for a wing tip detection indicate that the propulsion system impact on the vehicle elastic response could increase the detection by approximately ten percent.

  12. User's Guide for the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS): Version 2

    NASA Technical Reports Server (NTRS)

    Liu, Yuan; Frederick, Dean K.; DeCastro, Jonathan A.; Litt, Jonathan S.; Chan, William W.

    2012-01-01

    This report is a Users Guide for version 2 of the NASA-developed Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) software, which is a transient simulation of a large commercial turbofan engine (up to 90,000-lb thrust) with a realistic engine control system. The software supports easy access to health, control, and engine parameters through a graphical user interface (GUI). C-MAPSS v.2 has some enhancements over the original, including three actuators rather than one, the addition of actuator and sensor dynamics, and an improved controller, while retaining or improving on the convenience and user-friendliness of the original. C-MAPSS v.2 provides the user with a graphical turbofan engine simulation environment in which advanced algorithms can be implemented and tested. C-MAPSS can run user-specified transient simulations, and it can generate state-space linear models of the nonlinear engine model at an operating point. The code has a number of GUI screens that allow point-and-click operation, and have editable fields for user-specified input. The software includes an atmospheric model which allows simulation of engine operation at altitudes from sea level to 40,000 ft, Mach numbers from 0 to 0.90, and ambient temperatures from -60 to 103 F. The package also includes a power-management system that allows the engine to be operated over a wide range of thrust levels throughout the full range of flight conditions.

  13. Advances in SiC/SiC Composites for Aero-Propulsion

    NASA Technical Reports Server (NTRS)

    DiCarlo, James A.

    2013-01-01

    In the last decade, considerable progress has been made in the development and application of ceramic matrix composites consisting of silicon carbide (SiC) based matrices reinforced by small-diameter continuous-length SiC-based fibers. For example, these SiC/SiC composites are now in the early stages of implementation into hot-section components of civil aero-propulsion gas turbine engines, where in comparison to current metallic components they offer multiple advantages due to their lighter weight and higher temperature structural capability. For current production-ready SiC/SiC, this temperature capability for long time structural applications is 1250 degC, which is better than 1100 degC for the best metallic superalloys. Foreseeing that even higher structural reliability and temperature capability would continue to increase the advantages of SiC/SiC composites, progress in recent years has also been made at NASA toward improving the properties of SiC/SiC composites by optimizing the various constituent materials and geometries within composite microstructures. The primary objective of this chapter is to detail this latter progress, both fundamentally and practically, with particular emphasis on recent advancements in the materials and processes for the fiber, fiber coating, fiber architecture, and matrix, and in the design methods for incorporating these constituents into SiC/SiC microstructures with improved thermo-structural performance.

  14. Determination of trans vitamin K1 in infant and medical nutritional products using AOAC Method 999.15 with modified preparation and extraction procedures and C30 bonded phase chromatography: single-laboratory validation.

    PubMed

    Schimpf, Karen J; Thompson, Linda B; Schmitz, Daniel J

    2010-01-01

    Modifications were made to AOAC Official Method 999.15 to extend its applicability to specialty infant formulas containing hydrolyzed proteins and free amino acids, and to medical and adult nutritional products. Minor changes to the sample preparation procedure and chromatographic separation improved vitamin K1 recoveries and reduced chromatographic interferences in these types of matrixes. Currently AOAC Method 999.15 is applicable only to the determination of total vitamin K1 (phylloquione) in infant formula and milk (fluid, ready-to-feed, and powdered) containing > 1 microg vitamin K1/100 g solids. AOAC Method 999.15 recoveries of vitamin K1 were improved by altering sample sizes, extraction solvents and amounts, and the reagent addition order and amount of water or aqueous solutions added. The chromatographic separation of vitamin K1 in medical nutritional products containing canola and marine oils was improved, and trans vitamin K1 was separated from the biologically inactive cis isomer in all products with a C30 3 microm column and a 100% methanol mobile phase. With these modifications to the extraction procedure and chromatographic separation, AOAC Method 999.15 demonstrated acceptable precision and accuracy for the quantitation of trans vitamin K1 in specialty infant formulas containing hydrolyzed proteins and free amino acids, and medical and adult nutritional products. A single-laboratory validation of these minor modifications was completed. Fourteen different product matrixes were analyzed during validation. The intermediate precision averaged 4.15% RSD (range 2.52-5.81% RSD), and recovery data averaged 100.1% (range 92.2-109%).

  15. Laboratory Tests

    MedlinePlus

    Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor ... compare your results to results from previous tests. Laboratory tests are often part of a routine checkup ...

  16. [Good Laboratory Practice (GPL) and quality control in Dutch laboratories].

    PubMed

    Goudswaard, J

    1991-03-15

    A review of the origin of GLP (Good Laboratory Practice) and ISO (International Standard Organisation) directives is followed by a number of definitions of concepts such as quality, guarantees of quality, quality systems, etc. by laboratories (NEN 2653). These requirements are discussed in the paper. Certification is one of the guarantees of quality assessment by laboratories. Certification of laboratories is carried out by STERLAB (Laboratory Accreditation Board of The Netherlands) or the CCKL (National Coordination Committee for Quality Assurance for Health Care Laboratories in The Netherlands). In addition to certification, laboratories in the Netherlands are extremely active as regards external quality control (QC). QC is carried out by the various occupational groups. The paper finally closes with a discussion of future developments regarding quality control and certification in medical and veterinary diagnostic laboratories.

  17. In-Flight Laboratory Analysis

    NASA Technical Reports Server (NTRS)

    Baumann, David; Perusek, Gail; Nelson, Emily; Krihak, Michael; Brown, Dan

    2012-01-01

    One-year study objectives align with HRP requirements. HRP requirements include measurement panels for research and medical operations - These measurement panels are distinctly different. Instrument requirements are defined - Power, volume and mass not quite a critical limitation as for medical operations (deep space exploration missions). One-year evaluation goals will lead HHC towards in-flight laboratory analysis capability.

  18. Trial of Integrated Laboratory Practice

    ERIC Educational Resources Information Center

    Matsuo, Osamu; Takahashi, Yuzo; Abe, Chikara; Tanaka, Kunihiko; Nakashima, Akira; Morita, Hironobu

    2011-01-01

    In most laboratory practices for students in medical schools, a laboratory guidebook is given to the students, in which the procedures are precisely described. The students merely follow the guidebook without thinking deeply, which spoils the students and does not entice them to think creatively. Problem-based learning (PBL) could be one means for…

  19. 42 CFR 493.1405 - Standard; Laboratory director qualifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., physical, or biological science or medical technology from an accredited institution; (ii) Have at least 2... medical education credit hours in laboratory practice commensurate with the director responsibilities... obtained during medical residency. (For example, physicians certified either in hematology or...

  20. 75 FR 67749 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab... 97232, 503-413-5295/800-950-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology... Medical Branch, Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory). Pacific...

  1. 77 FR 20832 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ..., (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road... Affairs Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725...-747-3774 (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  2. 76 FR 31969 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... 72209-7056, 501-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical... Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725-2088..., (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  3. 77 FR 71605 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ...-202-2783. (Formerly: Forensic Toxicology Laboratory Baptist Medical Center.) Clinical Reference Lab...-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive..., Pasadena, TX 77504, 888-747-3774. (Formerly: University of Texas Medical Branch, Clinical...

  4. 76 FR 24501 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ...-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center) Clinical Reference Lab... 97232, 503-413-5295/800-950-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology... Medical Branch, Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory) Pacific...

  5. 76 FR 18770 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab... 97232, 503-413-5295/800-950-5295. Minneapolis Veterans Affairs Medical Center, Forensic Toxicology... Medical Branch, Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory). Pacific...

  6. 76 FR 40924 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab... Affairs Medical Center, Forensic Toxicology ] Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725...-747-3774 (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  7. 77 FR 5037 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ..., (Formerly: Forensic Toxicology Laboratory Baptist Medical Center); Clinical Reference Lab, 8433 Quivira Road... Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725-2088..., (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  8. 76 FR 61110 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ...-202-2783. (Formerly: Forensic Toxicology Laboratory Baptist Medical Center.) Clinical Reference Lab... Affairs Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725...-747-3774. (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  9. 76 FR 46309 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-02

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center) Clinical Reference Lab... Affairs Medical Center, Forensic Toxicology Laboratory, 1 Veterans Drive, Minneapolis, MN 55417, 612-725...-3774 (Formerly: University of Texas Medical Branch, Clinical Chemistry Division; UTMB...

  10. 76 FR 5379 - Clinical Laboratory Improvement Advisory Committee (CLIAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ..., revisions to the standards under which clinical laboratories are regulated; the impact on medical and... Clinical Laboratory Workforce; the National Institutes of Health Genetic Test Registry design and responses... HUMAN SERVICES Centers for Disease Control and Prevention Clinical Laboratory Improvement...

  11. Aeronautical-Satellite-Assisted Process Being Developed for Information Exchange Through Network Technologies (Aero-SAPIENT)

    NASA Technical Reports Server (NTRS)

    Zernic, Michael J.

    2001-01-01

    Communications technologies are being developed to address safety issues during aviation travel. Some of these technologies enable the aircraft to be in constant bidirectional communications with necessary systems, people, and other aircraft that are not currently in place today. Networking technologies, wireless datalinks, and advanced avionics techniques are areas of particular importance that the NASA Glenn Research Center has contributed. Glenn, in conjunction with the NASA Ames Research Center, NASA Dryden Flight Research Center, and NASA Langley Research Center, is investigating methods and applications that would utilize these communications technologies. In mid-June 2000, the flight readiness of the network and communications technologies were demonstrated via a simulated aircraft. A van simulating an aircraft was equipped with advanced phased-array antennas (Advanced Communications/Air Traffic Management (AC/ATM) Advanced Air Transportation Technologies (AATT) project) that used commercial Ku-band satellite communications to connect Glenn, Dryden, and Ames in a combined system ground test. This test simulated air-ground bidirectional transport of real-time digital audio, text, and video data via a hybrid network configuration that demonstrated the flight readiness of the network and communications technologies. Specifically, a Controller Pilot Data Link Communications application was used with other applications to demonstrate a multiprotocol capability via Internet-protocol encapsulated ATN (Aeronautical Telecommunications Network) data packets. The significance of this combined ground test is its contribution to the Aero Information Technology Base Program Level I milestone (Software Technology investment area) of a real-time data link for the National Airspace System. The objective of this milestone was to address multiprotocol technology applicable for real-time data links between aircraft, a satellite, and the ground as well as the ability to

  12. A Neural Network Aero Design System for Advanced Turbo-Engines

    NASA Technical Reports Server (NTRS)

    Sanz, Jose M.

    1999-01-01

    An inverse design method calculates the blade shape that produces a prescribed input pressure distribution. By controlling this input pressure distribution the aerodynamic design objectives can easily be met. Because of the intrinsic relationship between pressure distribution and airfoil physical properties, a Neural Network can be trained to choose the optimal pressure distribution that would meet a set of physical requirements. Neural network systems have been attempted in the context of direct design methods. From properties ascribed to a set of blades the neural network is trained to infer the properties of an 'interpolated' blade shape. The problem is that, especially in transonic regimes where we deal with intrinsically non linear and ill posed problems, small perturbations of the blade shape can produce very large variations of the flow parameters. It is very unlikely that, under these circumstances, a neural network will be able to find the proper solution. The unique situation in the present method is that the neural network can be trained to extract the required input pressure distribution from a database of pressure distributions while the inverse method will still compute the exact blade shape that corresponds to this 'interpolated' input pressure distribution. In other words, the interpolation process is transferred to a smoother problem, namely, finding what pressure distribution would produce the required flow conditions and, once this is done, the inverse method will compute the exact solution for this problem. The use of neural network is, in this context, highly related to the use of proper optimization techniques. The optimization is used essentially as an automation procedure to force the input pressure distributions to achieve the required aero and structural design parameters. A multilayered feed forward network with back-propagation is used to train the system for pattern association and classification.

  13. Novel Framework for Reduced Order Modeling of Aero-engine Components

    NASA Astrophysics Data System (ADS)

    Safi, Ali

    The present study focuses on the popular dynamic reduction methods used in design of complex assemblies (millions of Degrees of Freedom) where numerous iterations are involved to achieve the final design. Aerospace manufacturers such as Rolls Royce and Pratt & Whitney are actively seeking techniques that reduce computational time while maintaining accuracy of the models. This involves modal analysis of components with complex geometries to determine the dynamic behavior due to non-linearity and complicated loading conditions. In such a case the sub-structuring and dynamic reduction techniques prove to be an efficient tool to reduce design cycle time. The components whose designs are finalized can be dynamically reduced to mass and stiffness matrices at the boundary nodes in the assembly. These matrices conserve the dynamics of the component in the assembly, and thus avoid repeated calculations during the analysis runs for design modification of other components. This thesis presents a novel framework in terms of modeling and meshing of any complex structure, in this case an aero-engine casing. In this study the affect of meshing techniques on the run time are highlighted. The modal analysis is carried out using an extremely fine mesh to ensure all minor details in the structure are captured correctly in the Finite Element (FE) model. This is used as the reference model, to compare against the results of the reduced model. The study also shows the conditions/criteria under which dynamic reduction can be implemented effectively, proving the accuracy of Criag-Bampton (C.B.) method and limitations of Static Condensation. The study highlights the longer runtime needed to produce the reduced matrices of components compared to the overall runtime of the complete unreduced model. Although once the components are reduced, the assembly run is significantly. Hence the decision to use Component Mode Synthesis (CMS) is to be taken judiciously considering the number of

  14. Calibration of aero-structural reduced order models using full-field experimental measurements

    NASA Astrophysics Data System (ADS)

    Perez, R.; Bartram, G.; Beberniss, T.; Wiebe, R.; Spottswood, S. M.

    2017-03-01

    The structural response of hypersonic aircraft panels is a multi-disciplinary problem, where the nonlinear structural dynamics, aerodynamics, and heat transfer models are coupled. A clear understanding of the impact of high-speed flow effects on the structural response, and the potential influence of the structure on the local environment, is needed in order to prevent the design of overly-conservative structures, a common problem in past hypersonic programs. The current work investigates these challenges from a structures perspective. To this end, the first part of this investigation looks at the modeling of the response of a rectangular panel to an external heating source (thermo-structural coupling) where the temperature effect on the structure is obtained from forward looking infrared (FLIR) measurements and the displacement via 3D-digital image correlation (DIC). The second part of the study uses data from a previous series of wind-tunnel experiments, performed to investigate the response of a compliant panel to the effects of high-speed flow, to train a pressure surrogate model. In this case, the panel aero-loading is obtained from fast-response pressure sensitive paint (PSP) measurements, both directly and from the pressure surrogate model. The result of this investigation is the use of full-field experimental measurements to update the structural model and train a computational efficient model of the loading environment. The use of reduced order models, informed by these full-field physical measurements, is a significant step toward the development of accurate simulation models of complex structures that are computationally tractable.

  15. Numerical Prediction of Flow and Heat Transfer on lubricant Supplying and Scavenging Flow Path of an Aero-Engine Lubrication System

    NASA Astrophysics Data System (ADS)

    Huang, S. Q.; Liu, Z. X.; Lv, Y. G.; Zhang, L. F.; Xu, T.

    This paper presents a numerical model of internal flows on lubricant supplying and scavenging flow path of an aero-engine lubrication system. The numerical model was built in the General Analysis Software of Aero-engine Lubrication System (GASLS), developed by Northwestern Polytechnical University. The lubricant flow flux, pressure and temperature distribution at steady state were calculated. GASLS is a general purpose computer program employed a ID steady state network algorithm for analyzing flowrates, pressures and temperatures in a complex flow network. All kinds of aero-engine lubrication systems can be divided into finite correlative typical elements and nodes from which the calculation network is developed in GASLS. Special emphasis is put on how to use combinational elements which is a type of typical elements to replace some complex components such as bearing compartments, accessory drive gearboxes or heat exchangers. This method can reduce network complexity and improve calculation efficiency. The computational results show good agreement with experimental data.

  16. Host Model Uncertainties in Aerosol Radiative Forcing Estimates: Results from the AeroCom Prescribed Intercomparison Study

    SciTech Connect

    Stier, Phillip; Schutgens, Nick A.; Bellouin, N.; Bian, Huisheng; Boucher, Olivier; Chin, Mian; Ghan, Steven J.; Huneeus, N.; Kinne, Stefan; Lin, G.; Ma, Xiaoyan; Myhre, G.; Penner, J. E.; Randles, Cynthia; Samset, B. H.; Schulz, M.; Takemura, T.; Yu, Fangqun; Yu, Hongbin; Zhou, Cheng

    2013-03-20

    Simulated multi-model "diversity" in aerosol direct radiative forcing estimates is often perceived as mea- sure of aerosol uncertainty. However, current models used for aerosol radiative forcing calculations vary considerably in model components relevant for forcing calculations and the associated "host-model uncertainties" are generally convoluted with the actual aerosol uncertainty. In this AeroCom Prescribed intercomparison study we systematically isolate and quantify host model uncertainties on aerosol forcing experiments through prescription of identical aerosol radiative properties in nine participating models. Even with prescribed aerosol radiative properties,simulated clear-sky and all-sky aerosol radiative forcings show significant diversity. For a purely scattering case with globally constant optical depth of 0.2, the global-mean all-sky top-of-atmosphere radiative forcing is -4.51 Wm-2 and the inter-model standard deviation is 0.70 Wm-2, corresponding to a relative standard deviation of 15%. For a case with partially absorbing aerosol with an aerosol optical depth of 0.2 and single scattering albedo of 0.8, the forcing changes to 1.26 Wm-2, and the standard deviation increases to 1.21 W-2, corresponding to a significant relative standard deviation of 96%. However, the top-of-atmosphere forcing variability owing to absorption is low, with relative standard deviations of 9% clear-sky and 12% all-sky. Scaling the forcing standard deviation for a purely scattering case to match the sulfate radiative in the AeroCom Direct Effect experiment, demonstrates that host model uncertain- ties could explain about half of the overall sulfate forcing diversity of 0.13 Wm-2 in the AeroCom Direct Radiative Effect experiment. Host model errors in aerosol radiative forcing are largest in regions of uncertain host model components, such as stratocumulus cloud decks or areas with poorly constrained.

  17. AeroCom INSITU Project: Comparison of Aerosol Optical Properties from In-situ Surface Measurements and Model Simulations

    NASA Astrophysics Data System (ADS)

    Schmeisser, L.; Andrews, E.; Schulz, M.; Fiebig, M.; Zhang, K.; Randles, C. A.; Myhre, G.; Chin, M.; Stier, P.; Takemura, T.; Krol, M. C.; Bian, H.; Skeie, R. B.; da Silva, A. M., Jr.; Kokkola, H.; Laakso, A.; Ghan, S.; Easter, R. C.

    2015-12-01

    AeroCom, an open international collaboration of scientists seeking to improve global aerosol models, recently initiated a project comparing model output to in-situ, surface-based measurements of aerosol optical properties. The model/measurement comparison project, called INSITU, aims to evaluate the performance of a suite of AeroCom aerosol models with site-specific observational data in order to inform iterative improvements to model aerosol modules. Surface in-situ data have the unique property of being traceable to physical standards, which is a big asset in accomplishing the overarching goal of bettering the accuracy of aerosol processes and predicative capability of global climate models. The INSITU project looks at how well models reproduce aerosol climatologies on a variety of time scales, aerosol characteristics and behaviors (e.g., aerosol persistence and the systematic relationships between aerosol optical properties), and aerosol trends. Though INSITU is a multi-year endeavor, preliminary phases of the analysis, using GOCART and other models participating in this AeroCom project, show substantial model biases in absorption and scattering coefficients compared to surface measurements, though the sign and magnitude of the bias varies with location and optical property. Spatial patterns in the biases highlight model weaknesses, e.g., the inability of models to properly simulate aerosol characteristics at sites with complex topography (see Figure 1). Additionally, differences in modeled and measured systematic variability of aerosol optical properties suggest that some models are not accurately capturing specific aerosol co-dependencies, for example, the tendency of in-situ surface single scattering albedo to decrease with decreasing aerosol extinction coefficient. This study elucidates specific problems with current aerosol models and suggests additional model runs and perturbations that could further evaluate the discrepancies between measured and modeled

  18. A method for the assessment of operational severity for a high pressure turbine blade of an aero-engine

    NASA Astrophysics Data System (ADS)

    Haslam, Anthony; Abu, Abdullahi; Laskaridis, Panagiotis

    2015-12-01

    This paper provides a tool for the estimation of the operational severity of a high pressure turbine blade of an aero engine. A multidisciplinary approach using aircraft/ engine performance models which provide inputs to a thermo-mechanical fatigue damage model is presented. In the analysis, account is taken of blade size, blade metal temperature distribution, relevant heat transfer coefficients and mechanical and thermal stresses. The leading edge of the blade is selected as the critical part in the estimation of damage severity for different design and operational parameters. The study also suggests a method for production of operational severity data for the prediction of maintenance intervals.

  19. PREFACE: The 2nd International Conference on Geological, Geographical, Aerospace and Earth Sciences 2014 (AeroEarth 2014)

    NASA Astrophysics Data System (ADS)

    Lumban Gaol, Ford; Soewito, Benfano

    2015-01-01

    The 2nd International Conference on Geological, Geographical, Aerospace and Earth Sciences 2014 (AeroEarth 2014), was held at Discovery Kartika Plaza Hotel, Kuta, Bali, Indonesia during 11 - 12 October 2014. The AeroEarth 2014 conference aims to bring together researchers and engineers from around the world. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. Earth provides resources and the exact conditions to make life possible. However, with the advent of technology and industrialization, the Earth's resources are being pushed to the brink of depletion. Non-sustainable industrial practices are not only endangering the supply of the Earth's natural resources, but are also putting burden on life itself by bringing about pollution and climate change. A major role of earth science scholars is to examine the delicate balance between the Earth's resources and the growing demands of industrialization. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program as well as the invited and plenary speakers. This year, we received 98 papers and after rigorous review, 17 papers were accepted. The participants come from eight countries. There are four Parallel Sessions and two invited Speakers. It is an honour to present this volume of IOP Conference Series: Earth and Environmental Science (EES) and we deeply thank the authors for their enthusiastic and high-grade contributions. Finally, we would like to thank the conference chairmen, the members of the steering committee, the organizing committee

  20. Laboratory Building

    SciTech Connect

    Herrera, Joshua M.

    2015-03-01

    This report is an analysis of the means of egress and life safety requirements for the laboratory building. The building is located at Sandia National Laboratories (SNL) in Albuquerque, NM. The report includes a prescriptive-based analysis as well as a performance-based analysis. Following the analysis are appendices which contain maps of the laboratory building used throughout the analysis. The top of all the maps is assumed to be north.

  1. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Laboratory controls. 225.58 Section 225.58 Food...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS Product Quality Control § 225.58 Laboratory controls. (a) The periodic assay of medicated feeds for drug components provides a measure...

  2. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Laboratory controls. 225.58 Section 225.58 Food...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS Product Quality Control § 225.58 Laboratory controls. (a) The periodic assay of medicated feeds for drug components provides a measure...

  3. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Laboratory controls. 225.58 Section 225.58 Food...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS Product Quality Control § 225.58 Laboratory controls. (a) The periodic assay of medicated feeds for drug components provides a measure...

  4. Modeling C-Band Co-Channel Interference From AeroMACS Omni-Directional Antennas to Mobile Satellite Service Feeder Uplinks

    NASA Technical Reports Server (NTRS)

    Wilson, Jeffrey D.

    2011-01-01

    A new C-band (5091 to 5150 MHz) airport communications system designated as Aeronautical Mobile Airport Communications System (AeroMACS) is being planned under the Federal Aviation Administration s NextGen program. An interference analysis software program, Visualyse Professional (Transfinite Systems Ltd), is being utilized to provide guidelines on limitations for AeroMACS transmitters to avoid interference with other systems. A scenario consisting of a single omni-directional transmitting antenna at each of the major contiguous United States airports is modeled and the steps required to build the model are reported. The results are shown to agree very well with a previous study.

  5. Design, manufacturing and characterization of aero-elastically scaled wind turbine blades for testing active and passive load alleviation techniques within a ABL wind tunnel

    NASA Astrophysics Data System (ADS)

    Campagnolo, Filippo; Bottasso, Carlo L.; Bettini, Paolo

    2014-06-01

    In the research described in this paper, a scaled wind turbine model featuring individual pitch control (IPC) capabilities, and equipped with aero-elastically scaled blades featuring passive load reduction capabilities (bend-twist coupling, BTC), was constructed to investigate, by means of wind tunnel testing, the load alleviation potential of BTC and its synergy with active load reduction techniques. The paper mainly focus on the design of the aero-elastic blades and their dynamic and static structural characterization. The experimental results highlight that manufactured blades show desired bend-twist coupling behavior and are a first milestone toward their testing in the wind tunnel.

  6. Memorial Medical Center Nursing Clinical Simulation Laboratory

    DTIC Science & Technology

    2012-12-01

    care. J Surg Educ. 2011;68(6):472-7. Epub 2011/10/18. 3. Capella J, Smith S, Philp A, Putnam T, Gilbert C, Fry W, et al. Teamwork training improves...Roberts, Cathy Schwind, Christopher McDowell, David Griffin, Jarrod Wall, Christopher D. Wohltmann*, M.D., Hilary Sanfey, M.D., Audra Chestnut, Reed...J. Schwind, John A. Sutyak, Christopher McDowell, David Griffen, Jarrod Wall, Hilary Sanfey, Audra Chestnut, Andreas Meier, Christopher Wohltmann

  7. Medical Service Clinical Laboratory Procedures--Parasitology.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    This manual presents techniques for the collection and examination of specimens in the diagnosis of parasitic disease and in field surveys conducted to determine the extent of parasitic infections in human and animal populations. It discusses areas in which parasites are most likely to be found and the relationships of parasites, vectors, and…

  8. Annual Progress Report (SEATO Medical Research Laboratory)

    DTIC Science & Technology

    1975-03-01

    Dengue Shock Syndrome ," in Amos, B. (ed): Progress in Immunology, New York, Academic Press, 1971, pp 831 -838. 2. Halstead, S.B. : Observations Related...transmission is primarily genital to oral. The fact that oropharyngeal Infections of N. gonorrhoeae were detected in women visiting a dental clinic on a...causative in 8096 of female genital tract Infections (9). These organisms have also been found in normal vaginal secretiors (10). Therefore, they should

  9. AeroVironment Technician Marshall MacCready carefully lays a panel of solar cells into place on a wi

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Technician Marshall MacCready carefully lays a panel of solar cells into place on a wing section of the Helios Prototype flying wing at AeroVironment's Design Development Center in Simi Valley, California. More than 1,800 panels containing some 64,000 bi-facial cells, fabricated by SunPower, Inc., of Sunnyvale, California, have been installed on the solar-powered aircraft to provide electricity to its 14 motors and operating systems. Developed by AeroVironment under NASA's Environmental Research Aircraft and Sensor Technology (ERAST) project, the Helios Prototype is the forerunner of a planned fleet of slow-flying, long duration, high-altitude aircraft which can perform atmospheric science missions and serve as telecommunications relay platforms in the stratosphere. Target goals set by NASA for the giant 246-foot span flying wing include reaching and sustaining subsonic horizontal flight at 100,000 feet altitude in 2001, and sustained continuous flight for at least four days and nights above 50,000 feet altitude 2003 with the aid of a regenerative fuel cell-based energy storage system now being developed.

  10. Effective L/D: A Theoretical Approach to the Measurement of Aero-Structural Efficiency in Aircraft Design

    NASA Technical Reports Server (NTRS)

    Guynn, Mark D.

    2015-01-01

    There are many trade-offs in aircraft design that ultimately impact the overall performance and characteristics of the final design. One well recognized and well understood trade-off is that of wing weight and aerodynamic efficiency. Higher aerodynamic efficiency can be obtained by increasing wing span, usually at the expense of higher wing weight. The proper balance of these two competing factors depends on the objectives of the design. For example, aerodynamic efficiency is preeminent for sailplanes and long slender wings result. Although the wing weight-drag trade is universally recognized, aerodynamic efficiency and structural efficiency are not usually considered in combination. This paper discusses the concept of "aero-structural efficiency," which combines weight and drag characteristics. A metric to quantify aero-structural efficiency, termed effective L/D, is then derived and tested with various scenarios. Effective L/D is found to be a practical and robust means to simultaneously characterize aerodynamic and structural efficiency in the context of aircraft design. The primary value of the effective L/D metric is as a means to better communicate the combined system level impacts of drag and structural weight.

  11. An engineer at AeroVironment's Design Development Center inspects a set of silicon solar cells for p

    NASA Technical Reports Server (NTRS)

    2000-01-01

    An engineer at AeroVironment's Design Development Center in Simi Valley, California, closely inspects a set of silicon solar cells for potential defects. The cells, fabricated by SunPower, Inc., of Sunnyvale, California, are among 64,000 solar cells which have been installed on the Helios Prototype solar-powered aircraft to provide power to its 14 electric motors and operating systems. Developed by AeroVironment under NASA's Environmental Research Aircraft and Sensor Technology (ERAST) project, the Helios Prototype is the forerunner of a planned fleet of slow-flying, long duration, high-altitude aircraft which can perform atmospheric science missions and serve as telecommunications relay platforms in the stratosphere. Target goals set by NASA for the giant 246-foot span flying wing include reaching and sustaining subsonic horizontal flight at 100,000 feet altitude in 2001, and sustained continuous flight for at least four days and nights in 2003 with the aid of a regenerative fuel cell-based energy storage system now in development.

  12. Soot volume fraction measurements in aero-engine exhausts using extinction-calibrated backward laser-induced incandescence

    NASA Astrophysics Data System (ADS)

    Delhay, J.; Desgroux, P.; Therssen, E.; Bladh, H.; Bengtsson, P.-E.; Hönen, H.; Black, J. D.; Vallet, I.

    2009-06-01

    Control and reduction of soot particle emissions from aeronautic turbines requires a monitoring system suitable for quantification of these emissions. Currently, such emissions are estimated using the technique of smoke number. This is an extractive method, which is not sensitive enough for the low emission levels of modern gas turbines. Within a recent European project, AEROTEST, part of the project aimed at investigating an alternative soot monitoring technique, laser-induced incandescence (LII) as an in-situ optical diagnostic for quantification of soot emissions. For aero-engine applications, especially those involving large-scale turbines, it is necessary to perform the measurements at long distance from the turbine. The LII technique is favourable in this respect as it provides for non-intrusive measurements and, by detecting the isotropic LII signal along the same axis as the incoming laser beam (so called backward LII), both the laser and the detector can be built inside one system located several meters from the turbine. The concept was initiated in the previous European projects, AEROJET I and II. This paper describes the modified version of the system and the procedure developed to achieve reliable and quantitative soot volume fraction measurements in the exhausts of aero-engines. Application of the backward LII technique is demonstrated in the exhaust of a military turbojet engine for different engine speeds.

  13. Nonlinear Dynamic Modeling of a Supersonic Commercial Transport Turbo-Machinery Propulsion System for Aero-Propulso-Servo-Elasticity Research

    NASA Technical Reports Server (NTRS)

    Connolly, Joe; Carlson, Jan-Renee; Kopasakis, George; Woolwine, Kyle

    2015-01-01

    This paper covers the development of an integrated nonlinear dynamic model for a variable cycle turbofan engine, supersonic inlet, and convergent-divergent nozzle that can be integrated with an aeroelastic vehicle model to create an overall Aero-Propulso-Servo-Elastic (APSE) modeling tool. The primary focus of this study is to provide a means to capture relevant thrust dynamics of a full supersonic propulsion system by using relatively simple quasi-one dimensional computational fluid dynamics (CFD) methods that will allow for accurate control algorithm development and capture the key aspects of the thrust to feed into an APSE model. Previously, propulsion system component models have been developed and are used for this study of the fully integrated propulsion system. An overview of the methodology is presented for the modeling of each propulsion component, with a focus on its associated coupling for the overall model. To conduct APSE studies the described dynamic propulsion system model is integrated into a high fidelity CFD model of the full vehicle capable of conducting aero-elastic studies. Dynamic thrust analysis for the quasi-one dimensional dynamic propulsion system model is presented along with an initial three dimensional flow field model of the engine integrated into a supersonic commercial transport.

  14. Nonlinear Dynamic Modeling of a Supersonic Commercial Transport Turbo-Machinery Propulsion System for Aero-Propulso-Servo-Elasticity Research

    NASA Technical Reports Server (NTRS)

    Connolly, Joseph W.; Kopasakis, George; Carlson, Jan-Renee; Woolwine, Kyle

    2015-01-01

    This paper covers the development of an integrated nonlinear dynamic model for a variable cycle turbofan engine, supersonic inlet, and convergent-divergent nozzle that can be integrated with an aeroelastic vehicle model to create an overall Aero-Propulso-Servo-Elastic (APSE) modeling tool. The primary focus of this study is to provide a means to capture relevant thrust dynamics of a full supersonic propulsion system by using relatively simple quasi-one dimensional computational fluid dynamics (CFD) methods that will allow for accurate control algorithm development and capture the key aspects of the thrust to feed into an APSE model. Previously, propulsion system component models have been developed and are used for this study of the fully integrated propulsion system. An overview of the methodology is presented for the modeling of each propulsion component, with a focus on its associated coupling for the overall model. To conduct APSE studies the de- scribed dynamic propulsion system model is integrated into a high fidelity CFD model of the full vehicle capable of conducting aero-elastic studies. Dynamic thrust analysis for the quasi-one dimensional dynamic propulsion system model is presented along with an initial three dimensional flow field model of the engine integrated into a supersonic commercial transport.

  15. Polypyrrole/silver coaxial nanowire aero-sponges for temperature-independent stress sensing and stress-triggered Joule heating.

    PubMed

    He, Weina; Li, Guangyong; Zhang, Shangquan; Wei, Yong; Wang, Jin; Li, Qingwen; Zhang, Xuetong

    2015-04-28

    To obtain ideal sensing materials with nearly zero temperature coefficient resistance (TCR) for self-temperature-compensated pressure sensors, we proposed an Incipient Network Conformal Growth (INCG) technology to prepare hybrid and elastic porous materials: the nanoparticles (NPs) are first dispersed in solvent to form an incipient network, another component is then introduced to coat the incipient network conformally via wet chemical route. The conformal coatings not only endow NPs with high stability but also offer them additional structural elasticity, meeting requirements for future generations of portable, compressive and flexible devices. The resultant polypyrrole/silver coaxial nanowire hybrid aero-sponges prepared via INCG technology have been processed into a piezoresistive sensor with highly sensing stability (low TCR 0.86 × 10(-3)/°C), sensitivity (0.33 kPa(-1)), short response time (1 ms), minimum detectable pressure (4.93 Pa) after suffering repeated stimuli, temperature change and electric heating. Moreover, a stress-triggered Joule heater can be also fabricated mainly by the PPy-Ag NW hybrid aero-sponges with nearly zero temperature coefficient.

  16. Exploration Laboratory Analysis FY13

    NASA Technical Reports Server (NTRS)

    Krihak, Michael; Perusek, Gail P.; Fung, Paul P.; Shaw, Tianna, L.

    2013-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk, which is stated as the Risk of Inability to Adequately Treat an Ill or Injured Crew Member, and ExMC Gap 4.05: Lack of minimally invasive in-flight laboratory capabilities with limited consumables required for diagnosing identified Exploration Medical Conditions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability in future exploration missions. Mission architecture poses constraints on equipment and procedures that will be available to treat evidence-based medical conditions according to the Space Medicine Exploration Medical Conditions List (SMEMCL), and to perform human research studies on the International Space Station (ISS) that are supported by the Human Health and Countermeasures (HHC) element. Since there are significant similarities in the research and medical operational requirements, ELA hardware development has emerged as a joint effort between ExMC and HHC. In 2012, four significant accomplishments were achieved towards the development of exploration laboratory analysis for medical diagnostics. These achievements included (i) the development of high priority analytes for research and medical operations, (ii) the development of Level 1 functional requirements and concept of operations documentation, (iii) the selection and head-to-head competition of in-flight laboratory analysis instrumentation, and (iv) the phase one completion of the Small Business Innovation Research (SBIR) projects under the topic Smart Phone Driven Blood-Based Diagnostics. To utilize resources efficiently, the associated documentation and advanced technologies were integrated into a single ELA plan that encompasses ExMC and HHC development efforts. The requirements and high priority analytes was used in the selection of the four in-flight laboratory analysis performers. Based upon the

  17. Advanced Aero-Propulsive Mid-Lift-to-Drag Ratio Entry Vehicle for Future Exploration Missions

    NASA Technical Reports Server (NTRS)

    Campbell, C. H.; Stosaric, R. R; Cerimele, C. J.; Wong, K. A.; Valle, G. D.; Garcia, J. A.; Melton, J. E.; Munk, M. M.; Blades, E.; Kuruvila, G.; Picetti, D. J.; Hassan, B.; Kniskern, M. W.

    2012-01-01

    vehicle stage return, thus making ideas reality. These paradigm shifts include the technology maturation of advanced flexible thermal protection materials onto mid lift-to-drag ratio entry vehicles, the development of integrated supersonic aero-propulsive maneuvering, and the implementation of advanced asymmetric launch shrouds. These paradigms have significant overlap with launch vehicle stage return already being developed by the Air Force and several commercial space efforts. Completing the realization of these combined paradigms holds the key to a high-performing entry vehicle system capability that fully leverages multiple technology benefits to accomplish NASA's Exploration missions to atmospheric planetary destinations.

  18. Ray tracing simulation of aero-optical effect using multiple gradient index layer

    NASA Astrophysics Data System (ADS)

    Yang, Seul Ki; Seong, Sehyun; Ryu, Dongok; Kim, Sug-Whan; Kwon, Hyeuknam; Jin, Sang-Hun; Jeong, Ho; Kong, Hyun Bae; Lim, Jae Wan; Choi, Jong Hwa

    2016-10-01

    We present a new ray tracing simulation of aero-optical effect through anisotropic inhomogeneous media as supersonic flow field surrounds a projectile. The new method uses multiple gradient-index (GRIN) layers for construction of the anisotropic inhomogeneous media and ray tracing simulation. The cone-shaped projectile studied has 19° semi-vertical angle; a sapphire window is parallel to the cone angle; and an optical system of the projectile was assumed via paraxial optics and infrared image detector. The condition for the steady-state solver conducted through computational fluid dynamics (CFD) included Mach numbers 4 and 6 in speed, 25 km altitude, and 0° angle of attack (AoA). The grid refractive index of the flow field via CFD analysis and Gladstone-Dale relation was discretized into equally spaced layers which are parallel with the projectile's window. Each layer was modeled as a form of 2D polynomial by fitting the refractive index distribution. The light source of ray set generated 3,228 rays for varying line of sight (LOS) from 10° to 40°. Ray tracing simulation adopted the Snell's law in 3D to compute the paths of skew rays in the GRIN layers. The results show that optical path difference (OPD) and boresight error (BSE) decreases exponentially as LOS increases. The variation of refractive index decreases, as the speed of flow field increases the OPD and its rate of decay at Mach number 6 in speed has somewhat larger value than at Mach number 4 in speed. Compared with the ray equation method, at Mach number 4 and 10° LOS, the new method shows good agreement, generated 0.33% of relative root-mean-square (RMS) OPD difference and 0.22% of relative BSE difference. Moreover, the simulation time of the new method was more than 20,000 times faster than the conventional ray equation method. The technical detail of the new method and simulation is presented with results and implication.

  19. 21 CFR 226.58 - Laboratory controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Laboratory controls. 226.58 Section 226.58 Food...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Product Quality Control § 226.58 Laboratory controls. Laboratory controls shall include the establishment of adequate specifications and...

  20. 21 CFR 226.58 - Laboratory controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Laboratory controls. 226.58 Section 226.58 Food...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Product Quality Control § 226.58 Laboratory controls. Laboratory controls shall include the establishment of adequate specifications and...