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Sample records for aerobic process large

  1. Thinking big: towards ideal strains and processes for large-scale aerobic biofuels production

    SciTech Connect

    McMillan, James D.; Beckham, Gregg T.

    2016-12-22

    Global concerns about anthropogenic climate change, energy security and independence, and environmental consequences of continued fossil fuel exploitation are driving significant public and private sector interest and financing to hasten development and deployment of processes to produce renewable fuels, as well as bio-based chemicals and materials, towards scales commensurate with current fossil fuel-based production. Over the past two decades, anaerobic microbial production of ethanol from first-generation hexose sugars derived primarily from sugarcane and starch has reached significant market share worldwide, with fermentation bioreactor sizes often exceeding the million litre scale. More recently, industrial-scale lignocellulosic ethanol plants are emerging that produce ethanol from pentose and hexose sugars using genetically engineered microbes and bioreactor scales similar to first-generation biorefineries.

  2. [Sulfa-drug wastewater treatment with anaerobic/aerobic process].

    PubMed

    Wu, L; Zhang, H; Zhu, H; Zhang, Z; Zhuang, Y; Dai, S

    2001-09-01

    Sulfa drug wastewater was treated with anaerobic/aerobic process. The removal ratios of TOC reached about 50% in anaerobic phase and about 70% in aerobic phase respectively, while volume loading rate of TOC was about 1.2 kg/(m3.d) in anaerobic phase and about 0.6 kg/(m3.d) in aerobic phase. Removal of TOC in anaerobic phase was attributed to the reduction of sulfate.

  3. Anaerobic Metabolism: Linkages to Trace Gases and Aerobic Processes

    NASA Astrophysics Data System (ADS)

    Megonigal, J. P.; Hines, M. E.; Visscher, P. T.

    2003-12-01

    's surface area, they have a profound influence on the biogeochemistry of the planet. This is evident from the observation that the O2 and CH4 content of Earth's atmosphere are in extreme disequilibrium (Sagan et al., 1993). The combination of high aerobic primary production and anoxic sediments provided the large deposits of fossil fuels that have become vital and contentious sources of energy for modern industrialized societies. Anaerobic metabolism is responsible for the abundance of N2 in the atmosphere; otherwise N2-fixing bacteria would have consumed most of the N2 pool long ago (Schlesinger, 1997). Anaerobic microorganisms are common symbionts of termites, cattle, and many other animals, where they aid digestion. Nutrient and pollutant chemistry are strongly modified by the reduced conditions that prevail in wetland and aquatic ecosystems.This review of anaerobic metabolism emphasizes aerobic oxidation, because the two processes cannot be separated in a complete treatment of the topic. It is process oriented and highlights the fascinating microorganisms that mediate anaerobic biogeochemistry. We begin this review with a brief discussion of CO2 assimilation by autotrophs, the source of most of the reducing power on Earth, and then consider the biological processes that harness this potential energy. Energy liberation begins with the decomposition of organic macromolecules to relatively simple compounds, which are simplified further by fermentation. Methanogenesis is considered next because CH4 is a product of acetate fermentation, and thus completes the catabolism of organic matter, particularly in the absence of inorganic electron acceptors. Finally, the organisms that use nitrogen, manganese, iron, and sulfur for terminal electron acceptors are considered in order of decreasing free-energy yield of the reactions.

  4. Aerobic Digestion. Biological Treatment Process Control. Instructor's Guide.

    ERIC Educational Resources Information Center

    Klopping, Paul H.

    This unit on aerobic sludge digestion covers the theory of the process, system components, factors that affect the process performance, standard operational concerns, indicators of steady-state operations, and operational problems. The instructor's guide includes: (1) an overview of the unit; (2) lesson plan; (3) lecture outline (keyed to a set of…

  5. Two-stage process combines anaerobic and aerobic methods

    SciTech Connect

    Kayhanian, M.; Lindenauer, K.; Hardy, S.; Tchobanoglous, G.

    1991-03-01

    The organic fraction of the material diverted from landfills has potential to be utilized as a raw material to be recycled, used for the production of compost, converted to energy in waste-to-energy facilities, or used for the production of other end products. Given the uncertainties concerning the future availability, production costs, and market prices for conventional fuels, any potential source of alternate energy and alternative energy technologies deserve serious consideration. Faced with an uncertain energy future, several European countries have already started using biomass and MSW as a source of energy. An innovative high-solids anaerobic digestion/aerobic composting process currently under investigation at the University of California, Davis is as an ideal candidate for processing a large fraction of the organic matter in MSW. The principal advantages of this innovative process which is described and discussed in this paper are: (1) the recovery of biogas that can be used as a fuel for the production of energy, and (2) the production of humus-like material that can be used as a high-quality soil amendment or as boiler fuel. The fact that a liquid waste stream that needs further treatment is not generated in this process is another significant advantage.

  6. Aerobic and anaerobic cecal bacterial flora of commercially processed broilers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Differences in the bacterial flora of aerobic and anaerobic cultures of broiler ceca collected from a commercial poultry processing facility were determined. Bacterial isolates from cecal cultures were selected based on the ability of the bacteria to grow in media supplemented with lactate and succ...

  7. Effect of the process conditions of aerobic bioconversion on the characteristics of biologically processed brown coals

    SciTech Connect

    I.P. Ivanov

    2007-04-15

    The effect of the laboratory and pilot process conditions of the aerobic bioconversion of brown coals on the elemental composition and technical characteristics of the organic matter of the resulting biologically processed coals is reported.

  8. Biodegradation and detoxification of textile azo dyes by bacterial consortium under sequential microaerophilic/aerobic processes

    PubMed Central

    Lade, Harshad; Kadam, Avinash; Paul, Diby; Govindwar, Sanjay

    2015-01-01

    Release of textile azo dyes to the environment is an issue of health concern while the use of microorganisms has proved to be the best option for remediation. Thus, in the present study, a bacterial consortium consisting of Providencia rettgeri strain HSL1 and Pseudomonas sp. SUK1 has been investigated for degradation and detoxification of structurally different azo dyes. The consortium showed 98-99 % decolorization of all the selected azo dyes viz. Reactive Black 5 (RB 5), Reactive Orange 16 (RO 16), Disperse Red 78 (DR 78) and Direct Red 81 (DR 81) within 12 to 30 h at 100 mg L-1 concentration at 30 ± 0.2 °C under microaerophilic, sequential aerobic/microaerophilic and microaerophilic/aerobic processes. However, decolorization under microaerophilic conditions viz. RB 5 (0.26 mM), RO 16 (0.18 mM), DR 78 (0.20 mM) and DR 81 (0.23 mM) and sequential aerobic/microaerophilic processes viz. RB 5 (0.08 mM), RO 16 (0.06 mM), DR 78 (0.07 mM) and DR 81 (0.09 mM) resulted into the formation of aromatic amines. In distinction, sequential microaerophilic/ aerobic process doesn’t show the formation of amines. Additionally, 62-72 % reduction in total organic carbon content was observed in all the dyes decolorized broths under sequential microaerophilic/aerobic processes suggesting the efficacy of method in mineralization of dyes. Notable induction within the levels of azoreductase and NADH-DCIP reductase (97 and 229 % for RB 5, 55 and 160 % for RO 16, 63 and 196 % for DR 78, 108 and 258 % for DR 81) observed under sequential microaerophilic/aerobic processes suggested their critical involvements in the initial breakdown of azo bonds, whereas, a slight increase in the levels of laccase and veratryl alcohol oxidase confirmed subsequent oxidation of formed amines. Also, the acute toxicity assay with Daphnia magna revealed the nontoxic nature of the dye-degraded metabolites under sequential microaerophilic/aerobic processes. As biodegradation under sequential microaerophilic/aerobic

  9. A single aerobic exercise session accelerates movement execution but not central processing.

    PubMed

    Beyer, Kit B; Sage, Michael D; Staines, W Richard; Middleton, Laura E; McIlroy, William E

    2017-03-27

    Previous research has demonstrated that aerobic exercise has disparate effects on speed of processing and movement execution. In simple and choice reaction tasks, aerobic exercise appears to increase speed of movement execution while speed of processing is unaffected. In the flanker task, aerobic exercise has been shown to reduce response time on incongruent trials more than congruent trials, purportedly reflecting a selective influence on speed of processing related to cognitive control. However, it is unclear how changes in speed of processing and movement execution contribute to these exercise-induced changes in response time during the flanker task. This study examined how a single session of aerobic exercise influences speed of processing and movement execution during a flanker task using electromyography to partition response time into reaction time and movement time, respectively. Movement time decreased during aerobic exercise regardless of flanker congruence but returned to pre-exercise levels immediately after exercise. Reaction time during incongruent flanker trials decreased over time in both an aerobic exercise and non-exercise control condition indicating it was not specifically influenced by exercise. This disparate influence of aerobic exercise on movement time and reaction time indicates the importance of partitioning response time when examining the influence of aerobic exercise on speed of processing. The decrease in reaction time over time independent of aerobic exercise indicates that interpreting pre-to-post exercise changes in behavior requires caution.

  10. Aerobic Digestion. Student Manual. Biological Treatment Process Control.

    ERIC Educational Resources Information Center

    Klopping, Paul H.

    This manual contains the textual material for a single-lesson unit on aerobic sludge digestion. Topic areas addressed include: (1) theory of aerobic digestion; (2) system components; (3) performance factors; (4) indicators of stable operation; and (5) operational problems and their solutions. A list of objectives, glossary of key terms, and…

  11. Aerobic Exercise Training in Post-Polio Syndrome: Process Evaluation of a Randomized Controlled Trial

    PubMed Central

    Voorn, Eric L.; Koopman, Fieke S.; Brehm, Merel A.; Beelen, Anita; de Haan, Arnold; Gerrits, Karin H. L.; Nollet, Frans

    2016-01-01

    Objective To explore reasons for the lack of efficacy of a high intensity aerobic exercise program in post-polio syndrome (PPS) on cardiorespiratory fitness by evaluating adherence to the training program and effects on muscle function. Design A process evaluation using data from an RCT. Patients Forty-four severely fatigued individuals with PPS were randomized to exercise therapy (n = 22) or usual care (n = 22). Methods Participants in the exercise group were instructed to exercise 3 times weekly for 4 months on a bicycle ergometer (60–70% heart rate reserve). Results The attendance rate was high (median 89%). None of the participants trained within the target heart rate range during >75% of the designated time. Instead, participants exercised at lower intensities, though still around the anaerobic threshold (AT) most of the time. Muscle function did not improve in the exercise group. Conclusion Our results suggest that severely fatigued individuals with PPS cannot adhere to a high intensity aerobic exercise program on a cycle ergometer. Despite exercise intensities around the AT, lower extremity muscle function nor cardiorespiratory fitness improved. Improving the aerobic capacity in PPS is difficult through exercise primarily focusing on the lower extremities, and may require a more individualized approach, including the use of other large muscle groups instead. Trial Registration Netherlands National Trial Register NTR1371 PMID:27419388

  12. Large forging manufacturing process

    DOEpatents

    Thamboo, Samuel V.; Yang, Ling

    2002-01-01

    A process for forging large components of Alloy 718 material so that the components do not exhibit abnormal grain growth includes the steps of: a) providing a billet with an average grain size between ASTM 0 and ASTM 3; b) heating the billet to a temperature of between 1750.degree. F. and 1800.degree. F.; c) upsetting the billet to obtain a component part with a minimum strain of 0.125 in at least selected areas of the part; d) reheating the component part to a temperature between 1750.degree. F. and 1800.degree. F.; e) upsetting the component part to a final configuration such that said selected areas receive no strains between 0.01 and 0.125; f) solution treating the component part at a temperature of between 1725.degree. F. and 1750.degree. F.; and g) aging the component part over predetermined times at different temperatures. A modified process achieves abnormal grain growth in selected areas of a component where desirable.

  13. Process Improvements: Aerobic Food Waste Composting at ISF Academy

    NASA Astrophysics Data System (ADS)

    Lau, Y. K.

    2015-12-01

    ISF Academy, a school with 1500 students in Hong Kong, installed an aerobic food waste composting system in November of 2013. The system has been operational for over seven months; we will be making improvements to the system to ensure the continued operational viability and quality of the compost. As a school we are committed to reducing our carbon footprint and the amount of waste we send to the local landfill. Over an academic year we produce approximately 27 metric tons of food waste. Our system processes the food waste to compost in 14 days and the compost is used by our primary school students in a organic farming project.There are two areas of improvement: a) if the composting system becomes anaerobic, there is an odor problem that is noticed by the school community; we will be testing the use of a bio-filter to eliminate the odor problem and, b) we will be working with an equipment vendor from Australia to install an improved grease trap system. The grease and oil that is collected will be sold to a local company here in Hong Kong that processes used cooking oil for making biofuels. This system will include a two stage filtration system and a heated vessel for separating the oil from the waste water.The third project will be to evaluate biodegradable cutlery for the compositing in the system. Currently, we use a significant quantity of non-biodegradable cutlery that is then thrown away after one use. Several local HK companies are selling biodegradable cutlery, but we need to evaluate the different products to determine which ones will work with our composting system. The food waste composting project at ISF Academy demonstrates the commitment of the school community to a greener environment for HK, the above listed projects will improve the operation of the system.

  14. Maximal Aerobic and Anaerobic Power Generation in Large Crocodiles versus Mammals: Implications for Dinosaur Gigantothermy

    PubMed Central

    Seymour, Roger S.

    2013-01-01

    Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic. PMID:23861968

  15. Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

    PubMed

    Seymour, Roger S

    2013-01-01

    Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

  16. The association between aerobic fitness and language processing in children: implications for academic achievement.

    PubMed

    Scudder, Mark R; Federmeier, Kara D; Raine, Lauren B; Direito, Artur; Boyd, Jeremy K; Hillman, Charles H

    2014-06-01

    Event-related brain potentials (ERPs) have been instrumental for discerning the relationship between children's aerobic fitness and aspects of cognition, yet language processing remains unexplored. ERPs linked to the processing of semantic information (the N400) and the analysis of language structure (the P600) were recorded from higher and lower aerobically fit children as they read normal sentences and those containing semantic or syntactic violations. Results revealed that higher fit children exhibited greater N400 amplitude and shorter latency across all sentence types, and a larger P600 effect for syntactic violations. Such findings suggest that higher fitness may be associated with a richer network of words and their meanings, and a greater ability to detect and/or repair syntactic errors. The current findings extend previous ERP research explicating the cognitive benefits associated with greater aerobic fitness in children and may have important implications for learning and academic performance.

  17. Does an aerobic endurance programme have an influence on information processing in migraineurs?

    PubMed Central

    2014-01-01

    Background Migraine is a disorder of central information processing which is characterized by a reduced habituation of event-related potentials. There might be positive effects of aerobic exercise on brain function and pain. The aim of this study was to investigate the influence of exercise on information processing and clinical course of migraine. Methods 33 patients completed a ten-week aerobic exercise programme. To examine the influence of the treatment on information processing and attention, Trail Making Test (TMT) A and B, d2-Letter Cancellation Test (LCT) and recordings of the Contingent Negative Variation (CNV) were performed before and after the training. Results Patients showed a significant reduction of the migraine attack frequency, the iCNV-amplitude and the processing time for TMT-A and TMT-B after treatment. Moreover, there was a significant increase of the habituation and positive changes in parameters of attention (d2-LCT) after the training. Conclusions This study demonstrates that aerobic exercise programme influences central information processing and leads to clinical effects on the migraine symptomatology. The results can be interpreted in terms of an improvement of a dysfunctional information processing and a stimulus selection under aerobic exercise. PMID:24528557

  18. Investigation of the use of aerobic granules for the treatment of sugar beet processing wastewater.

    PubMed

    Kocaturk, Irem; Erguder, Tuba Hande

    2015-01-01

    The treatment of sugar beet processing wastewater in aerobic granular sequencing batch reactor (SBR) was examined in terms of chemical oxygen demand (COD) and nitrogen removal efficiency. The effect of sugar beet processing wastewater of high solid content, namely 2255 ± 250 mg/L total suspended solids (TSS), on granular sludge was also investigated. Aerobic granular SBR initially operated with the effluent of anaerobic digester treating sugar beet processing wastewater (Part I) achieved average removal efficiencies of 71 ± 30% total COD (tCOD), 90 ± 3% total ammonifiable nitrogen (TAN), 76 ± 24% soluble COD (sCOD) and 29 ± 4% of TSS. SBR was further operated with sugar beet processing wastewater (Part II), where the tCOD, TAN, sCOD and TSS removal efficiencies were 65 ± 5%, 61 ± 4%, 87 ± 1% and 58 ± 10%, respectively. This study indicated the applicability of aerobic granular SBRs for the treatment of both sugar beet processing wastewater and anaerobically digested processing wastewater. For higher solids removal, further treatment such as a sedimentation tank is required following the aerobic granular systems treating solid-rich wastewaters such as sugar beet processing wastewater. It was also revealed that the application of raw sugar beet processing wastewater slightly changed the aerobic granular sludge properties such as size, structure, colour, settleability and extracellular polymeric substance content, without any drastic and negative effect on treatment performance.

  19. Characterization of aerobic spore-forming bacteria associated with industrial dairy processing environments and product spoilage.

    PubMed

    Lücking, Genia; Stoeckel, Marina; Atamer, Zeynep; Hinrichs, Jörg; Ehling-Schulz, Monika

    2013-09-02

    Due to changes in the design of industrial food processing and increasing international trade, highly thermoresistant spore-forming bacteria are an emerging problem in food production. Minimally processed foods and products with extended shelf life, such as milk products, are at special risk for contamination and subsequent product damages, but information about origin and food quality related properties of highly heat-resistant spore-formers is still limited. Therefore, the aim of this study was to determine the biodiversity, heat resistance, and food quality and safety affecting characteristics of aerobic spore-formers in the dairy sector. Thus, a comprehensive panel of strains (n=467), which originated from dairy processing environments, raw materials and processed foods, was compiled. The set included isolates associated with recent food spoilage cases and product damages as well as isolates not linked to product spoilage. Identification of the isolates by means of Fourier-transform infrared spectroscopy and molecular methods revealed a large biodiversity of spore-formers, especially among the spoilage associated isolates. These could be assigned to 43 species, representing 11 genera, with Bacillus cereus s.l. and Bacillus licheniformis being predominant. A screening for isolates forming thermoresistant spores (TRS, surviving 100°C, 20 min) showed that about one third of the tested spore-formers was heat-resistant, with Bacillus subtilis and Geobacillus stearothermophilus being the prevalent species. Strains producing highly thermoresistant spores (HTRS, surviving 125°C, 30 min) were found among mesophilic as well as among thermophilic species. B. subtilis and Bacillus amyloliquefaciens were dominating the group of mesophilic HTRS, while Bacillus smithii and Geobacillus pallidus were dominating the group of thermophilic HTRS. Analysis of spoilage-related enzymes of the TRS isolates showed that mesophilic strains, belonging to the B. subtilis and B. cereus

  20. Two-stage anaerobic and post-aerobic mesophilic digestion of sewage sludge: Analysis of process performance and hygienization potential.

    PubMed

    Tomei, M Concetta; Mosca Angelucci, Domenica; Levantesi, Caterina

    2016-03-01

    Sequential anaerobic-aerobic digestion has been demonstrated to be effective for enhanced sludge stabilization, in terms of increased solid reduction and improvement of sludge dewaterability. In this study, we propose a modified version of the sequential anaerobic-aerobic digestion process by operating the aerobic step under mesophilic conditions (T=37 °C), in order to improve the aerobic degradation kinetics of soluble and particulate chemical oxygen demand (COD). Process performance has been assessed in terms of "classical parameters" such as volatile solids (VS) removal, biogas production, COD removal, nitrogen species, and polysaccharide and protein fate. The aerobic step was operated under intermittent aeration to achieve nitrogen removal. Aerobic mesophilic conditions consistently increased VS removal, providing 32% additional removal vs. 20% at 20 °C. Similar results were obtained for nitrogen removal, increasing from 64% up to 99% at the higher temperature. Improved sludge dewaterability was also observed with a capillary suction time decrease of ~50% during the mesophilic aerobic step. This finding may be attributable to the decreased protein content in the aerobic digested sludge. The post-aerobic digestion exerted a positive effect on the reduction of microbial indicators while no consistent improvement of hygienization related to the increased temperature was observed. The techno-economic analysis of the proposed digestion layout showed a net cost saving for sludge disposal estimated in the range of 28-35% in comparison to the single-phase anaerobic digestion.

  1. Microbiology of the frankfurter process: salmonella and natural aerobic flora.

    PubMed

    Palumbo, S A; Huhtanen, C N; Smith, J L

    1974-04-01

    Salmonella senftenberg 775W added to frankfurter emulsion was killed during normal processing in the smoke house when internal product temperature was 71.1 C (160 F) or above. The thermal destruction point of S. senftenberg 775W in frankfurters (temperature at which no viable cells were detected) was a function of the length of time of the process rather than of the starting number of cells. Heating of frankfurters to 73.9 C (165 F) substantially reduced the total non-salmonella count. For total non-salmonella bacterial flora and salmonella, relatively little thermal destruction occurred below 43.3 C (110 F). The heating step can bring about a 7-log cycle decrease (10(8) to 10(1)/g) of bacteria present in the raw emulsion. The flora of this high-bacteriological-count raw emulsion was predominantly gram-negative rods. Variation in the number of bacteria (both total and salmonella) surviving at various temperatures during processing was attributed to slight variations in the temperature pattern of the smoke house during its operation. An integration process was devised which allowed calculation of exposure to temperatures above 110 F (43.3 C) on the basis of degree-minutes. Plots of degree-minutes versus log of surviving bacteria were linear. The salmonella plot had a greater slope than that of the total non-salmonella flora, indicating that salmonellae are more heat sensitive than the bacterial population as a whole. The predominant bacteria surviving the heating step were micrococci. These micrococci were able to increase in number in or on the frankfurters during storage at 5 C.

  2. Simulation of aerobic and anaerobic biodegradation processes at a crude oil spill site

    USGS Publications Warehouse

    Essaid, Hedeff I.; Bekins, Barbara A.; Godsy, E. Michael; Warren, Ean; Baedecker, Mary Jo; Cozzarelli, Isabelle M.

    1995-01-01

    A two-dimensional, multispecies reactive solute transport model with sequential aerobic and anaerobic degradation processes was developed and tested. The model was used to study the field-scale solute transport and degradation processes at the Bemidji, Minnesota, crude oil spill site. The simulations included the biodegradation of volatile and nonvolatile fractions of dissolved organic carbon by aerobic processes, manganese and iron reduction, and methanogenesis. Model parameter estimates were constrained by published Monod kinetic parameters, theoretical yield estimates, and field biomass measurements. Despite the considerable uncertainty in the model parameter estimates, results of simulations reproduced the general features of the observed groundwater plume and the measured bacterial concentrations. In the simulation, 46% of the total dissolved organic carbon (TDOC) introduced into the aquifer was degraded. Aerobic degradation accounted for 40% of the TDOC degraded. Anaerobic processes accounted for the remaining 60% of degradation of TDOC: 5% by Mn reduction, 19% by Fe reduction, and 36% by methanogenesis. Thus anaerobic processes account for more than half of the removal of DOC at this site.

  3. Biological treatment of high-pH and high-concentration black liquor of cotton pulp by an immediate aerobic-anaerobic-aerobic process.

    PubMed

    Lihong, Miao; Furong, Li; Jinli, Wen

    2009-01-01

    In this study, an immediate aerobic-anaerobic-aerobic (O/A/O) biological process was established for the treatment of black liquor of cotton pulp and was tested by both laboratory-scale batch experiment and pilot-scale continuous experiment. The effects of the hydraulic retention time (HRT) were studied, as were the alkaliphilic bacteria number, the culturing temperature and the concentration of black liquor on COD (chemical oxygen demand) removal. The total COD (COD(tot)) removal rate of the novel O/A/O process, for a black liquor with influent COD(tot) over 8,000 mg/L and pH above 12.8, was 68.7+/-4% which is similar with that of the traditional acidic-anaerobic-aerobic process (64.9+/-3%). The first aerobic stage based on alkaliphilic bacteria was the crucial part of the process, which was responsible for decreasing the influent pH from above 12 to an acceptable level for the following treatment unit. The average generation time of the alkaliphilic bacteria in the black liquor was about 36 minutes at 40 degrees C in a batch aerobic activated sludge system. The efficiency of the first aerobic stage was affected greatly by the temperature. The COD(tot) removal at 55 degrees C was much lower in comparison with the COD(tot) removal at 45 degrees C or 50 degrees C. Both the laboratory-scale batch experiments and the pilot-scale continuous experiment showed that the COD(tot) removal rate could reach about 65% for original black liquor with a pH of about 13.0 and a COD of 18,000-22,000 mg/L by the immediate O/A/O process. The first aerobic stage gave an average COD(tot) removal of 45.5% at 35 degrees C (HRT = 72 h) at a volume loading rate of 3.4 kg COD m(-3) d(-1).

  4. Trace metal pyritization variability in response to mangrove soil aerobic and anaerobic oxidation processes.

    PubMed

    Machado, W; Borrelli, N L; Ferreira, T O; Marques, A G B; Osterrieth, M; Guizan, C

    2014-02-15

    The degree of iron pyritization (DOP) and degree of trace metal pyritization (DTMP) were evaluated in mangrove soil profiles from an estuarine area located in Rio de Janeiro (SE Brazil). The soil pH was negatively correlated with redox potential (Eh) and positively correlated with DOP and DTMP of some elements (Mn, Cu and Pb), suggesting that pyrite oxidation generated acidity and can affect the importance of pyrite as a trace metal-binding phase, mainly in response to spatial variability in tidal flooding. Besides these aerobic oxidation effects, results from a sequential extraction analyses of reactive phases evidenced that Mn oxidized phase consumption in reaction with pyrite can be also important to determine the pyritization of trace elements. Cumulative effects of these aerobic and anaerobic oxidation processes were evidenced as factors affecting the capacity of mangrove soils to act as a sink for trace metals through pyritization processes.

  5. [Start-up and operation characteristics of aerobic granular short-cut nitrification process].

    PubMed

    Yang, Yang; Zuo, Jian-E; Bu, De-Hua; Gu, Xia-Sheng

    2007-11-01

    In a lab-scale aerated upflow sludge bed (AUSB) reactor inoculated with the mixture of anaerobic granular sludge and aerobic sludge, using synthetic ammonia-rich wastewater as influent, aerobic short-cut nitrification granules were cultivated. After that, the short-cut nitrification reactor could be operated stably with very high efficiency under mesophilic condition (30 approximately 35 degrees C), and the influent loading rate (NH4(+) -N) could reach 2.5 approximately 3.0 kg/(m3 x d). The ammonia removal efficiency and the short-cut nitrification ratio (NO2(-)/NOx(-)) were above 90% respectively. Some organic COD (about 100 mg/L) existed in the influent had no obvious effects on the operation of the short-cut nitrification process. The short-cut nitrification reactor could also be operated stably with very high efficiency under ambient temperature (about 20 degrees C).

  6. Central treatment of different emulsion wastewaters by an integrated process of physicochemically enhanced ultrafiltration and anaerobic-aerobic biofilm reactor.

    PubMed

    Zhang, Weijun; Xiao, Ping; Wang, Dongsheng

    2014-05-01

    The feasibility of an integrated process of ultrafiltration (UF) enhanced by combined chemical emulsion breaking with vibratory shear and anaerobic/aerobic biofilm reactor for central treatment of different emulsion wastewaters was investigated. Firstly, it was found that calcium chloride exhibited better performance in oil removal than other inorganic salts. Chemical demulsification pretreatment could efficiently improve oil removal and membrane filtration in emulsion wastewater treatment by VSEP. According to aerobic batch bioassay, UF permeate exhibited good biodegradability and could be further treated with biological process. Additionally, pilot test indicated that anaerobic-aerobic biofilm exhibited an excellent ability against rise in organic loading and overall chemical oxygen demand (COD) removal efficiency of biological system was more than 93% of which 82% corresponded to the anaerobic process and 11% to the aerobic degradation. The final effluent of integrated process could meet the "water quality standards for discharge to municipal sewers" in China.

  7. Effects of aerobic exercise under different thermal conditions on human somatosensory processing.

    PubMed

    Nakata, Hiroki; Oshiro, Misaki; Namba, Mari; Shibasaki, Manabu

    2016-10-01

    The present study aimed to investigate the effects of aerobic exercise on human somatosensory processing recorded by somatosensory evoked potentials (SEPs) under temperate [TEMP, 20°C and 40% relative humidity (RH)] and hot (HOT, 35°C and 30% RH) environments. Fifteen healthy subjects performed 4 × 15-min bouts of a moderate cycling exercise [mean power output: 156.5 ± 7.7 (SE) W], with a 10-min rest period and received a posterior tibial nerve stimulation at the left ankle before and after each exercise bout; SEPs were recorded in five sessions; 1st (pre), 2nd (post-1st exercise bout), 3rd (post-2nd exercise bout), 4th (post-3rd exercise bout), and 5th (post-4th exercise bout). The peak latencies and amplitudes of the P37, N50, P60, and N70 components at Cz were evaluated. The latencies of P37, N50, P60, and N70 were significantly shorter with the repetition of aerobic exercise, and these shortened latencies were significantly greater in the HOT condition than in the TEMP condition (P37: 3rd, P < 0.05, and 5th, P < 0.01; P60: 4th, P < 0.05, and 5th, P < 0.01; N70: 4th, P < 0.05, and 5th, P < 0.001). No significant differences were observed in the amplitudes of any SEP component under either thermal condition. These results suggest that the conduction velocity of the ascending somatosensory input was accelerated by increases in body temperature, and aerobic exercise did not alter the strength of neural activity in cortical somatosensory processing.

  8. An Analysis of Aerobic Capacity in a Large United States Population,

    DTIC Science & Technology

    1985-04-29

    L. Aaro and J.E. Johnsen. Physical activity and health: Part I. J. Cardiac Rehab. 4:316-326, 1984. 40. Vogel, J.A., J.E. Wright, J.F. Patton, D.S...reference to chronic physical activity and obesity. J. Appl. Physiol. 11:72-81, 1957. 6. Cooper, K.H. and A. Zechner. Physical fitness in United States and...motivational effect on the amount of habitual physical activity and aerobic training participation. The end result is a moderate negative relationship

  9. Climatic thresholds for pedogenic iron oxides under aerobic conditions: Processes and their significance in paleoclimate reconstruction

    NASA Astrophysics Data System (ADS)

    Long, Xiaoyong; Ji, Junfeng; Barrón, Vidal; Torrent, José

    2016-10-01

    Iron oxides are widely distributed across the surface of the Earth as a result of the aerobic weathering of primary Fe-bearing minerals. Pedogenic iron oxides which consist mainly of hematite (Hm), goethite (Gt), maghemite (Mgh), are often concentrated synchronously in aerobic soils under low to moderate rainfall regimes. Magnetic susceptibility (χ) and redness, which respectively reflect the content of Mgh and Hm in soils, are considered reasonable pedogenic and climatic indicators in soil taxonomy and paleorainfall reconstruction. However, under high rainfall regimes, the grain growth of Mgh and transformation to Hm, combined with the prior formation of Gt under conditions of high relative humidity (RH), can result in magnetic reduction and dramatic yellowing of soils and sediments, which explains the existence of rainfall thresholds for Mgh and Hm at a large scale even before the pedogenic environment turns anaerobic. In order to capture the rainfall thresholds for Mgh and Hm occurring under aerobic conditions, we explored a tropical transect across a granitic region where the soil color turned from red to yellow under a wide rainfall range of 900-2200 mm/yr and a corresponding mean annual RH range of 77%-85%. We observed a lower rainfall threshold of ∼1500 mm/yr and a corresponding RH ∼80% for Mgh and Hm along this transect, as well as a higher rainfall threshold of ∼1700 mm/yr and a corresponding RH of ∼81% for Gt and total pedogenic iron oxides (citrate/bicarbonate/dithionite-extractable Fe, Fed). Cross-referencing with comparable studies in temperate and subtropical regions, we noted that the rainfall or RH thresholds for Fed and Hm or Mgh likewise increase with temperature. Moreover, the different thresholds for total and individual iron oxide phase indicates that a negative correlation between chemical weathering intensity and redness or χ in sediment sequences can occur under the prevalent climate regime just between their thresholds. Finally

  10. Characteristics of Biological Nitrogen Removal in a Multiple Anoxic and Aerobic Biological Nutrient Removal Process

    PubMed Central

    Wang, Huoqing; Guan, Yuntao; Li, Li; Wu, Guangxue

    2015-01-01

    Two sequencing batch reactors, one with the conventional anoxic and aerobic (AO) process and the other with the multiple AO process, were operated to examine characteristics of biological nitrogen removal, especially of the multiple AO process. The long-term operation showed that the total nitrogen removal percentage of the multiple AO reactor was 38.7% higher than that of the AO reactor. In the multiple AO reactor, at the initial SBR cycle stage, due to the occurrence of simultaneous nitrification and denitrification, no nitrite and/or nitrate were accumulated. In the multiple AO reactor, activities of nitrite oxidizing bacteria were inhibited due to the multiple AO operating mode applied, resulting in the partial nitrification. Denitrifiers in the multiple AO reactor mainly utilized internal organic carbon for denitrification, and their activities were lower than those of denitrifiers in the AO reactor utilizing external organic carbon. PMID:26491676

  11. Evaluation of the Removal of Indicator Bacteria from Domestic Sludge Processed by Autothermal Thermophilic Aerobic Digestion (ATAD)

    PubMed Central

    Piterina, Anna V.; Bartlett, John; Pembroke, Tony J.

    2010-01-01

    The degradation of sludge solids in an insulated reactor during Autothermal Thermophilic Aerobic Digestion (ATAD) processing results in auto-heating, thermal treatment and total solids reduction, however, the ability to eliminate pathogenic organisms has not been analysed under large scale process conditions. We evaluated the ATAD process over a period of one year in a two stage, full scale Irish ATAD plant established in Killarney and treating mixed primary and secondary sludge, by examining the sludge microbiologically at various stages during and following ATAD processing to determine its ability to eliminate indicator organisms. Salmonella spp. (pathogen) and fecal-coliform (indicator) densities were well below the limits used to validate class A biosolids in the final product. Enteric pathogens present at inlet were deactivated during the ATAD process and were not detected in the final product using both traditional microbial culture and molecular phylogenetic techniques. A high DNase activity was detected in the bulk sludge during the thermophilic digestion stage which may be responsible for the rapid turn over of DNA from lysed cells and the removal of mobile DNA. These results offer assurance for the safe use of ATAD sludge as a soil supplement following processing. PMID:20948933

  12. Acute aerobic exercise influences the inhibitory process in the go/no-go task in humans.

    PubMed

    Akatsuka, Kosuke; Yamashiro, Koya; Nakazawa, Sho; Mitsuzono, Ryouichi; Maruyama, Atsuo

    2015-07-23

    This study evaluated the influence of acute aerobic exercise on the human inhibitory system. For studies on the neural mechanisms of somato-motor inhibitory processing in humans, the go/no-go task is a useful paradigm for recording event-related potentials. Ten subjects performed somatosensory go/no-go tasks in a control condition and exercise condition. In the control condition, the subjects performed the go/no-go task before and after 20 min of rest. In the exercise condition, the subjects performed the go/no-go task before and after 15 min of treadmill running with the exercise intensity set individually for each subject at 50% of peak oxygen intake. We successfully recorded a clear-cut N140 component under all conditions, and found that the peak amplitude of no-go-N140 at Fz and Cz was significantly enhanced during moderate exercise. In contrast, there were no significant changes in Fz and Cz in the control condition. These results suggest that moderate exercise can affect the amplitude of no-go-N140, which could be interpreted as an index of the human inhibition process in the central nervous system. The human inhibitory system is an important cognitive process, and this system may underlie the hypothetical ability of physical exercise to maintain and improve cognitive performance throughout the lifespan.

  13. Combined Fenton oxidation and aerobic biological processes for treating a surfactant wastewater containing abundant sulfate.

    PubMed

    Wang, Xiao-Jun; Song, Yang; Mai, Jun-Sheng

    2008-12-30

    The present study is to investigate the treatment of a surfactant wastewater containing abundant sulfate by Fenton oxidation and aerobic biological processes. The operating conditions have been optimized. Working at an initial pH value of 8, a Fe2+ dosage of 600mgL(-1) and a H2O2 dosage of 120mgL(-1), the chemical oxidation demand (COD) and linear alkylbenzene sulfonate (LAS) were decreased from 1500 and 490mgL(-1) to 230 and 23mgL(-1) after 40min of Fenton oxidation, respectively. Advanced oxidation pretreatment using Fenton reagent was very effective at enhancing the biodegradability of this kind of wastewater. The wastewater was further treated by a bio-chemical treatment process based on an immobilized biomass reactor with a hydraulic detention time (HRT) of 20h after Fenton oxidation pretreatment under the optimal operating conditions. It was found that the COD and LAS of the final effluent were less than 100 and 5mgL(-1), corresponding to a removal efficiencies of over 94% and 99%, respectively.

  14. Microbial community analysis involved in the aerobic/extended-idle process performing biological phosphorus removal.

    PubMed

    Zeng, Tian-jing; Yang, Guo-jing; Wang, Dong-bo; Li, Xiao-ming; Zheng, Wei; Yang, Qi; Zeng, Guang-ming

    2013-01-01

    Recently, it has been found that biological phosphorus removal can be achieved in an aerobic/extended-idle (AEI) process using both glucose and acetate as the sole substrate. However, the microbial consortiums involved in glucose-fed and acetate-fed systems have not yet been characterized. Thus the aims of this paper were to investigate the diversities and dynamics of bacterial communities during the acclimation period, and to quantify polyphosphate-accumulating organisms (PAOs) and glycogen-accumulating organisms (GAOs) in the systems. The phylogenetic analysis showed that the microbial communities were mainly composed of phylum Proteobacteria, Bacteroidetes, Chlorobi and another six kinds of unclassified bacteria. Fluorescence in-situ hybridization (FISH) analysis revealed that PAOs and GAOs accounted for 43 ± 7 and 16 ± 3% of all bacteria in the glucose-fed system, and 19 ± 4 and 35 ± 5% of total bacteria in the acetate-fed system, respectively. The results showed that the conventional PAOs could thrive in the AEI process, and a defined anaerobic zone was not necessarily required for putative PAOs growth.

  15. Numerical modeling analysis of VOC removal processes in different aerobic vertical flow systems for groundwater remediation.

    PubMed

    De Biase, Cecilia; Carminati, Andrea; Oswald, Sascha E; Thullner, Martin

    2013-11-01

    Vertical flow systems filled with porous medium have been shown to efficiently remove volatile organic contaminants (VOCs) from contaminated groundwater. To apply this semi-natural remediation strategy it is however necessary to distinguish between removal due to biodegradation and due to volatile losses to the atmosphere. Especially for (potentially) toxic VOCs, the latter needs to be minimized to limit atmospheric emissions. In this study, numerical simulation was used to investigate quantitatively the removal of volatile organic compounds in two pilot-scale water treatment systems: an unplanted vertical flow filter and a planted one, which could also be called a vertical flow constructed wetland, both used for the treatment of contaminated groundwater. These systems were intermittently loaded with contaminated water containing benzene and MTBE as main VOCs. The highly dynamic but permanently unsaturated conditions in the porous medium facilitated aerobic biodegradation but could lead to volatile emissions of the contaminants. Experimental data from porous material analyses, flow rate measurements, solute tracer and gas tracer test, as well as contaminant concentration measurements at the boundaries of the systems were used to constrain a numerical reactive transport modeling approach. Numerical simulations considered unsaturated water flow, transport of species in the aqueous and the gas phase as well as aerobic degradation processes, which made it possible to quantify the rates of biodegradation and volatile emissions and calculating their contribution to total contaminant removal. A range of degradation rates was determined using experimental results of both systems under two operation modes and validated by field data obtained at different operation modes applied to the filters. For both filters, simulations and experimental data point to high biodegradation rates, if the flow filters have had time to build up their removal capacity. For this case volatile

  16. Comparison of aerobic and anaerobic stability indices through a MSW biological treatment process.

    PubMed

    Ponsá, Sergio; Gea, Teresa; Alerm, Llorenç; Cerezo, Javier; Sánchez, Antoni

    2008-12-01

    A complex mechanical-biological waste treatment plant designed for the processing of mixed municipal solid wastes (MSW) and source-selected organic fraction of municipal solid wastes (OFMSW) has been studied by using stability indices related to aerobic (respiration index, RI) and anaerobic conditions (biochemical methane potential, BMP). Several selected stages of the plant have been characterized: waste inputs, mechanically treated wastes, anaerobically digested materials and composted wastes, according to the treatment sequence used in the plant. Results obtained showed that the main stages responsible for waste stabilization were the two first stages: mechanical separation and anaerobic digestion with a diminution of both RI and BMP around 40% and 60%, respectively, whereas the third stage, composting of digested materials, produced lesser biological degradation (20-30%). The results related to waste stabilization were similar in both lines (MSW and OFMSW), although the indices obtained for MSW were significantly lower than those obtained for OFMSW, which demonstrated a high biodegradability of OFMSW. The methodology proposed can be used for the characterization of organic wastes and the determination of the efficiency of operation units used in mechanical-biological waste treatment plants.

  17. Evolution of heavy metal speciation during the aerobic composting process of sewage sludge.

    PubMed

    Liu, Yangsheng; Ma, Lanlan; Li, Yaqiong; Zheng, Liting

    2007-03-01

    The contents of heavy metals and their bioavailability to the soil-plant system were the major limitation to the application of sewage sludge compost in soil. This study was conducted to determine the evolution of heavy metal speciation in the course of an aerobic composting, and investigate the influence of changes of composting process parameters including pH, temperature and organic matter (OM) content on distribution of heavy metal speciation in composted sludge. The sequential extraction procedure developed by Tessier et al. was used in sludge compost to determine the heavy metal speciation. Results showed that, during composting, (1) the contents of the residue fraction for Pb, Zn and Cd were decreased but those for Ni and Cr were increased; the Cu residue fraction was almost constant; (2) the contents of the total mobile fractions (including fractions 1-4) for Zn and Pb were significantly increased, but the increase of those for Cu and Ni were not so remarkable; (3) there were significant degrees of correlation between heavy metal fractions and changes of some selected parameters (for example, pH, composting temperature, and OM content). Only the content of the total mobile fractions for Cu could be predictable from its total content. For the prediction of the total mobile fractions of Zn, Ni, Cd and Cr, the R(2) value was significantly increased by the inclusion of other variables such as pH, temperature and OM content.

  18. Aerobic thermophilic treatment of sewage sludge at pilot plant scale. 2. Technical solutions and process design.

    PubMed

    Ponti, C; Sonnleitner, B; Fiechter, A

    1995-01-15

    The performance of the ATS process depends essentially on the oxygen transfer efficiency. Improvement of the mass transfer capacity of a bioreactor allowed to reduce the incubation time necessary to attain sludge stabilization. It is important to use equipment with a high aeration efficiency such as an injector aeration system. The ratio between the total oxygen consumption and the organic matter degradation (delta COD) ranged between 0.4 and 0.8 in the pilot plant, whereas 1.23 was found in completely mixed bioreactors (Bomio, 1990). No significant improvement of the bacterial degradation efficiency was attained with a specific power input exceeding 6-8 kW m-3. A mean residence time of less than 1 d allowed organic matter removals up to 40% with specific power consumption of 10 kWh kg-1 COD oxidized. The sludge hygienization is one of the objectives and benefits of the thermophilic treatment: not only temperature but also the total solids content were important factors affecting inactivation of pathogens. The inactivation rate was promoted by the increase of temperature, while the residual colony forming units decreased with reducing the total solids content of sewage sludge. It is concluded that continuous operation mode would not affect the quality of the hygienization but could display the high degradation potential of the aerobic system.

  19. Comprehensive microbial analysis of combined mesophilic anaerobic-thermophilic aerobic process treating high-strength food wastewater.

    PubMed

    Jang, Hyun Min; Ha, Jeong Hyub; Park, Jong Moon; Kim, Mi-Sun; Sommer, Sven G

    2015-04-15

    A combined mesophilic anaerobic-thermophilic aerobic process was used to treat high-strength food wastewater in this study. During the experimental period, most of solid residue from the mesophilic anaerobic reactor (R1) was separated by centrifugation and introduced into the thermophilic aerobic reactor (R2) for further digestion. Then, thermophilic aerobically-digested sludge was reintroduced into R1 to enhance reactor performance. The combined process was operated with two different Runs: Run I with hydraulic retention time (HRT) = 40 d (corresponding OLR = 3.5 kg COD/m(3) d) and Run II with HRT = 20 d (corresponding OLR = 7 kg COD/m(3)). For a comparison, a single-stage mesophilic anaerobic reactor (R3) was operated concurrently with same OLRs and HRTs as the combined process. During the overall digestion, all reactors showed high stability without pH control. The combined process demonstrated significantly higher organic matter removal efficiencies (over 90%) of TS, VS and COD and methane production than did R3. Quantitative real-time PCR (qPCR) results indicated that higher populations of both bacteria and archaea were maintained in R1 than in R3. Pyrosequencing analysis revealed relatively high abundance of phylum Actinobacteria in both R1 and R2, and a predominance of phyla Synergistetes and Firmicutes in R3 during Run II. Furthermore, R1 and R2 shared genera (Prevotella, Aminobacterium, Geobacillus and Unclassified Actinobacteria), which suggests synergy between mesophilic anaerobic digestion and thermophilic aerobic digestion. For archaea, in R1 methanogenic archaea shifted from genus Methanosaeta to Methanosarcina, whereas genera Methanosaeta, Methanobacterium and Methanoculleus were predominant in R3. The results demonstrated dynamics of key microbial populations that were highly consistent with an enhanced reactor performance of the combined process.

  20. Aerobic Exercise for Reducing Migraine Burden: Mechanisms, Markers, and Models of Change Processes

    PubMed Central

    Irby, Megan B.; Bond, Dale S.; Lipton, Richard B.; Nicklas, Barbara; Houle, Timothy T.; Penzien, Donald B.

    2016-01-01

    Background Engagement in regular exercise routinely is recommended as an intervention for managing and preventing migraine, and yet empirical support is far from definitive. We possess at best a weak understanding of how aerobic exercise and resulting change in aerobic capacity influence migraine, let alone the optimal parameters for exercise regimens as migraine therapy (eg, who will benefit, when to prescribe, optimal types, and doses/intensities of exercise, level of anticipated benefit). These fundamental knowledge gaps critically limit our capacity to deploy exercise as an intervention for migraine. Overview Clear articulation of the markers and mechanisms through which aerobic exercise confers benefits for migraine would prove invaluable and could yield insights on migraine pathophysiology. Neurovascular and neuroinflammatory pathways, including an effect on obesity or adiposity, are obvious candidates for study given their role both in migraine as well as the changes known to accrue with regular exercise. In addition to these biological pathways, improvements in aerobic fitness and migraine alike also are mediated by changes in psychological and sociocognitive factors. Indeed a number of specific mechanisms and pathways likely are operational in the relationship between exercise and migraine improvement, and it remains to be established whether these pathways operate in parallel or synergistically. As heuristics that might conceptually benefit our research programs here forward, we: (1) provide an extensive listing of potential mechanisms and markers that could account for the effects of aerobic exercise on migraine and are worthy of empirical exploration and (2) present two exemplar conceptual models depicting pathways through which exercise may serve to reduce the burden of migraine. Conclusion Should the promise of aerobic exercise as a feasible and effective migraine therapy be realized, this line of endeavor stands to benefit migraineurs (including the

  1. Enhanced performance of denitrifying sulfide removal process at high carbon to nitrogen ratios under micro-aerobic condition.

    PubMed

    Chen, Chuan; Zhang, Ruo-Chen; Xu, Xi-Jun; Fang, Ning; Wang, Ai-Jie; Ren, Nan-Qi; Lee, Duu-Jong

    2017-02-11

    The success of denitrifying sulfide removal (DSR) processes, which simultaneously degrade sulfide, nitrate and organic carbon in the same reactor, counts on synergetic growths of autotrophic and heterotrophic denitrifiers. Feeding wastewaters at high C/N ratio would stimulate overgrowth of heterotrophic bacteria in the DSR reactor so deteriorating the growth of autotrophic denitrifiers. The DSR tests at C/N=1.26:1, 2:1 or 3:1 and S/N =5:6 or 5:8 under anaerobic (control) or micro-aerobic conditions were conducted. Anaerobic DSR process has <50% sulfide removal with no elemental sulfur transformation. Under micro-aerobic condition to remove <5% sulfide by chemical oxidation pathway, 100% sulfide removal is achieved by the DSR consortia. Continuous-flow tests under micro-aerobic condition have 70% sulfide removal and 55% elemental sulfur recovery. Trace oxygen enhances activity of sulfide-oxidizing, nitrate-reducing bacteria to accommodate properly the wastewater with high C/N ratios.

  2. Anaerobic-aerobic treatment of purified terephthalic acid (PTA) effluent; a techno-economic alternative to two-stage aerobic process.

    PubMed

    Pophali, G R; Khan, R; Dhodapkar, R S; Nandy, T; Devotta, S

    2007-12-01

    This paper addresses the treatment of purified terephthalic acid (PTA) effluent using anaerobic and aerobic processes. Laboratory studies were carried out on flow proportionate composite wastewater generated from the manufacturing of PTA. An activated sludge process (ASP-two stage and single stage) and an upflow anaerobic fixed film fixed bed reactor (AFFFBR) were used, individually and in combination. The performance of a full-scale ETP under existing operating conditions was also studied. Full scale ETP studies revealed that the treatment of PTA effluent using a two-stage ASP alone does not meet treated effluent quality within the prescribed Indian Standards. The biomass produced in the two stage ASP was very viscous and fluffy and the sludge volume index (SVI) was very high (200-450 ml/g). However, pretreatment of PTA effluent using an upflow AFFFBR ensured substantial reduction in BOD (63%) and COD (62%) with recovery of biogas at 1.8-1.96 l/l effluent treated at a volumetric loading rate (VLR) 4-5 kg COD/m(3) d. The methane content in the biogas varied between 55% and 60%. The pretreated effluent from the upflow AFFFBR was then treated through a single stage ASP. The biomass produced in the ASP after anaerobic treatment had very good settlability (SVI: 75-90 ml/g) as compared to the two stage ASP and the treated effluent quality with respect to BOD, COD and SS was within the prescribed Indian Standards. The alternative treatment process comprising an upflow AFFFBR and a single stage ASP ensured net power saving of 257 kW and in addition generated 442 kW of power through the AFFFBR.

  3. Optimization of hydraulic shear parameters and reactor configuration in the aerobic granular sludge process.

    PubMed

    Zhu, Liang; Zhou, Jiaheng; Yu, Haitian; Xu, Xiangyang

    2015-01-01

    The hydraulic shear acts as an important selection pressure in aerobic sludge granulation. The effects of the hydraulic shear rate and reactor configuration on structural characteristics of aerobic granule in view of the hydromechanics. The hydraulic shear analysis was proposed to overcome the limitation of using superficial gas velocity (SGV) to express the hydraulic shear stress. Results showed that the stronger hydraulic shear stress with SGV above 2.4 cm s(-1) promoted the microbial aggregation, and favoured the structural stability of the granular sludge. According to the hydraulic shear analysis, the total shear rate reached (0.56-2.31)×10(5) s(-1) in the granular reactor with a larger ratio of height to diameter (H/D), and was higher than that in the reactor with smaller H/D, where the sequencing airlift bioreactor with smaller H/D had a high total shear rate under the same SGV. Results demonstrated that the granular reactor could provide a stronger hydraulic shear stress which promotes the formation and structural stability of aerobic granules.

  4. [Effect of pilot UASB-SFSBR-MAP process for the large scale swine wastewater treatment].

    PubMed

    Wang, Liang; Chen, Chong-Jun; Chen, Ying-Xu; Wu, Wei-Xiang

    2013-03-01

    In this paper, a treatment process consisted of UASB, step-fed sequencing batch reactor (SFSBR) and magnesium ammonium phosphate precipitation reactor (MAP) was built to treat the large scale swine wastewater, which aimed at overcoming drawbacks of conventional anaerobic-aerobic treatment process and SBR treatment process, such as the low denitrification efficiency, high operating costs and high nutrient losses and so on. Based on the treatment process, a pilot engineering was constructed. It was concluded from the experiment results that the removal efficiency of COD, NH4(+) -N and TP reached 95.1%, 92.7% and 88.8%, the recovery rate of NH4(+) -N and TP by MAP process reached 23.9% and 83.8%, the effluent quality was superior to the discharge standard of pollutants for livestock and poultry breeding (GB 18596-2001), mass concentration of COD, TN, NH4(+) -N, TP and SS were not higher than 135, 116, 43, 7.3 and 50 mg x L(-1) respectively. The process developed was reliable, kept self-balance of carbon source and alkalinity, reached high nutrient recovery efficiency. And the operating cost was equal to that of the traditional anaerobic-aerobic treatment process. So the treatment process could provide a high value of application and dissemination and be fit for the treatment pf the large scale swine wastewater in China.

  5. Cloud Based Processing of Large Photometric Surveys

    NASA Astrophysics Data System (ADS)

    Farivar, R.; Brunner, R. J.; Santucci, R.; Campbell, R.

    2013-10-01

    Astronomy, as is the case with many scientific domains, has entered the realm of being a data rich science. Nowhere is this reflected more clearly than in the growth of large area surveys, such as the recently completed Sloan Digital Sky Survey (SDSS) or the Dark Energy Survey, which will soon obtain PB of imaging data. The data processing on these large surveys is a major challenge. In this paper, we demonstrate a new approach to this common problem. We propose the use of cloud-based technologies (e.g., Hadoop MapReduce) to run a data analysis program (e.g., SExtractor) across a cluster. Using the intermediate key/value pair design of Hadoop, our framework matches objects across different SExtractor invocations to create a unified catalog from all SDSS processed data. We conclude by presenting our experimental results on a 432 core cluster and discuss the lessons we have learned in completing this challenge.

  6. Seasonal and wastewater stream variation of trace organic compounds in a dairy processing plant aerobic bioreactor.

    PubMed

    Heaven, Michael W; Wild, Karl; Verheyen, Vincent; Cruickshank, Alicia; Watkins, Mark; Nash, David

    2011-09-01

    Bioreactors are often an integral part of dairy factory efforts to reduce the biological oxygen demand of their wastewater. In this study, infeed, mixed liquor and supernatant samples of an aerobic bioreactor used by a dairy factory in South-Eastern Australia were analyzed for nutrients and organic compounds using gas chromatography-mass spectrometry and physicochemical analyses. Despite different concentrations of organic inputs into the bioreactor, nutrients and trace organic compounds were reduced significantly (i.e. average concentration of trace organic compounds: infeed=1681 μg/L; mixed liquor=257 μg/L; supernatant=23 μg/L). However, during one sampling period the bioreactor was adversely affected by the organic loading. Trace organic compounds in the samples were predominantly fatty acids associated with animal products. The analyses suggest that it is possible to trace a disruptive input (i.e. infeed with high organic carbon concentrations) into an aerobic bioreactor by measuring concentrations of fatty acids or ammonia.

  7. Aerobic degradation of BDE-209 by Enterococcus casseliflavus: Isolation, identification and cell changes during degradation process.

    PubMed

    Tang, Shaoyu; Yin, Hua; Chen, Shuona; Peng, Hui; Chang, Jingjing; Liu, Zehua; Dang, Zhi

    2016-05-05

    Decabromodiphenyl ether (BDE-209) is one of the most commonly used brominated flame retardants that have contaminated the environment worldwide. Microbial bioremediation has been considered as an effective technique to remove these sorts of persistent organic pollutants. Enterococcus casseliflavus, a gram-positive bacterium capable of aerobically transforming BDE-209, was isolated by our team from sediments in Guiyu, an e-waste dismantling area in Guangdong Province, China. To promote microbial bioremediation of BDE-209 and elucidate the mechanism behind its aerobic degradation, the effects of BDE-209 on the cell changes of E. casseliflavus were examined in this study. The experimental results demonstrated that the high cell surface hydrophobicity (CSH) of E. casseliflavus made the bacteria absorb hydrophobic BDE-209 more easily. E. casseliflavus responded to BDE-209 stress, resulting in an increase in cell membrane permeability and accumulation of BDE-209 inside the cell. The differential expression of intracellular protein was analyzed through two-dimensional gel electrophoresis (2-DE). More than 50 differentially expressed protein spots were reproducibly detected, including 25 up, and 25 down regulated after a 4 days exposure. Moreover, the apoptotic-like cell changes were observed during E. casseliflavus mediated degradation of BDE-209 by means of flow cytometry.

  8. Aerobic biodegradation of sludge with high hydrocarbon content generated by a Mexican natural gas processing facility.

    PubMed

    Roldán-Carrillo, T; Castorena-Cortés, G; Zapata-Peñasco, I; Reyes-Avila, J; Olguín-Lora, P

    2012-03-01

    The biodegradation of oil sludge from Mexican sour gas and petrochemical facilities contaminated with a high content of hydrocarbons, 334.7 ± 7.0 g kg(-1) dry matter (dm), was evaluated. Studies in microcosm systems were carried out in order to determine the capacity of the native microbiota in the sludge to reduce hydrocarbon levels under aerobic conditions. Different carbon/nitrogen/phosphorous (C/N/P) nutrient ratios were tested. The systems were incubated at 30 °C and shaken at 100 rpm. Hydrocarbon removals from 32 to 51% were achieved in the assays after 30 days of incubation. The best assay had C/N/P ratio of 100/1.74/0.5. The results of the Microtox(®) and Ames tests indicated that the original sludge was highly toxic and mutagenic, whereas the best assay gave a final product that did not show toxicity or mutagenicity.

  9. Start-up of the SHARON and ANAMMOX process in landfill bioreactors using aerobic and anaerobic ammonium oxidising biomass.

    PubMed

    Shalini, S Sri; Joseph, Kurian

    2013-12-01

    The main aim of this study is to analyse the feasibility to use aerobic ammonium oxidising bacteria (AOB) and anammox/AnAOB biomass enriched from mined municipal solid waste for in situ SHARON and ANAMMOX processes in laboratory scale landfill bioreactors (LFBR) for ammonia nitrogen removal. For this purpose, three LFBRs were operated as Control (without biomass seed), SHARON (with AOB biomass seed) and ANAMMOX (with anammox biomass seed) for 315 days. Results showed nitrogen loading rate of 1.0 kg N/d was effectively removed in SHARON and ANAMMOX LFBR. In SHARON LFBR, partial nitritation efficiency reached up to 98.5% with AOB population of MPN of 5.1 × 10(6)/mL obtained. ANAMMOX LFBR gave evolution of 95% of nitrogen gas as the end product confirmed the ANAMMOX process. Nitrogen transformations, biomass development and hydrazine and hydroxylamine formation authenticated the enriched AOB and anammox biomass activity in landfill bioreactors.

  10. Treatment of artificial soybean wastewater anaerobic effluent in a continuous aerobic-anaerobic coupled (CAAC) process with excess sludge reduction.

    PubMed

    Wang, Jun; Li, Xiaoxia; Fu, Weichao; Wu, Shihan; Li, Chun

    2012-12-01

    In this study, treatment of artificial soybean wastewater anaerobic effluent was studied in a continuous aerobic-anaerobic coupled (CAAC) process. The focus was on COD and nitrogen removal as well as excess sludge reduction. During the continuous operation without reflux, the COD removal efficiency was 96.5% at the optimal hydraulic retention time (HRT) 1.3 days. When HRT was shortened to 1.0 day, reflux from anaerobic zone to moving bed biofilm reactor (MBBR) was introduced. The removal efficiencies of COD and TN were 94.4% and 76.0% at the optimal reflux ratio 30%, respectively. The sludge yield coefficient of CAAC was 0.1738, the simultaneous removal of COD and nitrogen with in situ sludge reduction could be achieved in this CAAC process. The sludge reduction mechanism was discussed by soluble components variation along the water flow.

  11. Reduced expression of cytochrome oxidases largely explains cAMP inhibition of aerobic growth in Shewanella oneidensis

    PubMed Central

    Yin, Jianhua; Meng, Qiu; Fu, Huihui; Gao, Haichun

    2016-01-01

    Inhibition of bacterial growth under aerobic conditions by elevated levels of cyclic adenosine 3′,5′-monophosphate (cAMP), first revealed more than 50 years ago, was attributed to accumulation of toxic methylglyoxal (MG). Here, we report a Crp-dependent mechanism rather than MG accumulation that accounts for the phenotype in Shewanella oneidensis, an emerging research model for the bacterial physiology. We show that a similar phenotype can be obtained by removing CpdA, a cAMP phosphodiesterase that appears more effective than its Escherichia coli counterpart. Although production of heme c and cytochromes c is correlated well with cAMP levels, neither is sufficient for the retarded growth. Quantities of overall cytochromes c increased substantially in the presence of elevated cAMP, a phenomenon resembling cells respiring on non-oxygen electron acceptors. In contrast, transcription of Crp-dependent genes encoding both cytochromes bd and cbb3 oxidases is substantially repressed under the same condition. Overall, our results suggest that cAMP of elevated levels drives cells into a low-energetic status, under which aerobic respiration is inhibited. PMID:27076065

  12. Fates of chlorinated volatile organic compounds in aerobic biological treatment processes: the effects of aeration and sludge addition.

    PubMed

    Chen, Wei-Hsiang; Yang, Wen-Ben; Yuan, Chung-Shin; Yang, Jun-Chen; Zhao, Qing-Liang

    2014-05-01

    The emission of volatile organic compounds (VOCs) from wastewater treatment plants (WWTPs) is becoming an environmental issue of increasing concern. As biological treatment has been considered as one important approach for VOC removal, lab-scale batch experiments were conducted in this study to investigate the fates of four chlorinated hydrocarbons, including chloroform, carbon tetrachloride, trichloroethylene (TCE), and tetrachloroethylene (PERC), in the biological treatment processes with respect to the effects of aeration and sludge addition. The VOC concentrations in the phases of air, water, and sludge under four simulated treatment stages (the first sedimentation, the forepart and rear part of aerobic biological treatment, and the second sedimentation) were analyzed. The results were used to understand the three-phase partitioning of these compounds and to estimate their potentials for volatilization and biological sorption and degradation in these technologies with the concept of fugacity. It was observed that the VOCs were mainly present in the water phase through the experiments. The effects of aeration or sludge addition on the fates of these VOCs occurred but appeared to be relatively limited. The concentration distributions of the VOCs were well below the reported partitioning coefficients. It was suggested that these compounds were unsaturated in the air and sludge phases, enhancing their potentials for volatilization and biological sorption/degradation through the processes. However, the properties of these chlorinated VOCs such as the volatility, polarity, or even biodegradability caused by their structural characteristics (e.g., the number of chlorine, saturated or unsaturated) may represent more significant factors for their fates in the aerobic biological treatment processes. These findings prove the complication behind the current knowledge of VOC pollutions in WWTPs and are of help to manage the adverse impacts on the environment and public

  13. Treatment of leather industry wastewater by aerobic biological and Fenton oxidation process.

    PubMed

    Mandal, Tamal; Dasgupta, Dalia; Mandal, Subhasis; Datta, Siddhartha

    2010-08-15

    Degradation of leather industry wastewater by sole aerobic treatment incorporating Thiobacillus ferrooxidans, Fenton's reagents, and combined treatment was investigated in this study. The sole treatment by Fenton's oxidation involving the introduction of 6g FeSO(4) and 266 g H(2)O(2) in a liter of wastewater at pH of 3.5 and 30 degrees C for 30 min at batch conditions reduced COD, BOD(5), sulfide, total chromium and color up to 69%, 72%, 88%, 5%, 100% and T. ferrooxidans alone showed maximum reduction to an extent of 77, 80, 85, 52, 89, respectively, in 21 d treatment at pH 2.5, FeSO(4) 16 g/L and temperature of 30 degrees C. The combined treatment at batch conditions involving 30 min chemical treatment by Fenton's oxidation followed by 72 h biochemical treatment by T. ferrooxidans at batch conditions gave rise up to 93%, 98%, 72%, 62% and 100% removal efficiencies of COD, BOD, sulfide, chromium and color at pH of 2.5 and 30 degrees C. Decrease in photo absorption of the Fenton's reagent treated samples, as compared to the banks, at 280, 350 and 470 nm wave lengths was observed. This may be the key factor for stimulating the biodegradation by T. ferrooxidans.

  14. Metaproteomics reveals major microbial players and their biodegradation functions in a large-scale aerobic composting plant.

    PubMed

    Liu, Dongming; Li, Mingxiao; Xi, Beidou; Zhao, Yue; Wei, Zimin; Song, Caihong; Zhu, Chaowei

    2015-11-01

    Composting is an appropriate management alternative for municipal solid waste; however, our knowledge about the microbial regulation of this process is still scare. We employed metaproteomics to elucidate the main biodegradation pathways in municipal solid waste composting system across the main phases in a large-scale composting plant. The investigation of microbial succession revealed that Bacillales, Actinobacteria and Saccharomyces increased significantly with respect to abundance in composting process. The key microbiologic population for cellulose degradation in different composting stages was different. Fungi were found to be the main producers of cellulase in earlier phase. However, the cellulolytic fungal communities were gradually replaced by a purely bacterial one in active phase, which did not support the concept that the thermophilic fungi are active through the thermophilic phase. The effective decomposition of cellulose required the synergy between bacteria and fungi in the curing phase.

  15. Metaproteomics reveals major microbial players and their biodegradation functions in a large-scale aerobic composting plant

    PubMed Central

    Liu, Dongming; Li, Mingxiao; Xi, Beidou; Zhao, Yue; Wei, Zimin; Song, Caihong; Zhu, Chaowei

    2015-01-01

    Composting is an appropriate management alternative for municipal solid waste; however, our knowledge about the microbial regulation of this process is still scare. We employed metaproteomics to elucidate the main biodegradation pathways in municipal solid waste composting system across the main phases in a large-scale composting plant. The investigation of microbial succession revealed that Bacillales, Actinobacteria and Saccharomyces increased significantly with respect to abundance in composting process. The key microbiologic population for cellulose degradation in different composting stages was different. Fungi were found to be the main producers of cellulase in earlier phase. However, the cellulolytic fungal communities were gradually replaced by a purely bacterial one in active phase, which did not support the concept that the thermophilic fungi are active through the thermophilic phase. The effective decomposition of cellulose required the synergy between bacteria and fungi in the curing phase. PMID:25989417

  16. Photorefractive processing for large adaptive phased arrays

    NASA Astrophysics Data System (ADS)

    Weverka, Robert T.; Wagner, Kelvin; Sarto, Anthony

    1996-03-01

    An adaptive null-steering phased-array optical processor that utilizes a photorefractive crystal to time integrate the adaptive weights and null out correlated jammers is described. This is a beam-steering processor in which the temporal waveform of the desired signal is known but the look direction is not. The processor computes the angle(s) of arrival of the desired signal and steers the array to look in that direction while rotating the nulls of the antenna pattern toward any narrow-band jammers that may be present. We have experimentally demonstrated a simplified version of this adaptive phased-array-radar processor that nulls out the narrow-band jammers by using feedback-correlation detection. In this processor it is assumed that we know a priori only that the signal is broadband and the jammers are narrow band. These are examples of a class of optical processors that use the angular selectivity of volume holograms to form the nulls and look directions in an adaptive phased-array-radar pattern and thereby to harness the computational abilities of three-dimensional parallelism in the volume of photorefractive crystals. The development of this processing in volume holographic system has led to a new algorithm for phased-array-radar processing that uses fewer tapped-delay lines than does the classic time-domain beam former. The optical implementation of the new algorithm has the further advantage of utilization of a single photorefractive crystal to implement as many as a million adaptive weights, allowing the radar system to scale to large size with no increase in processing hardware.

  17. [Effect of different volume loading of aerobic/anaerobic zone on nitrogen and phosphorus removal by biofilm and granular sludge coupling process].

    PubMed

    Yin, Hang; Liu, Chang; Gao, Hui; Gao, Da-Wen

    2014-05-01

    The effect of different aerobic/anaerobic zone volume loading on nitrogen and phosphorus removal by biological film and granular coupling process was investigated using a self-designed Biofilm/Granular sludge coupling reactor. Three operating modes were conducted in the experiment. In operating mode I ,the volume of aerobic zone was 9. 66 L, and the volume of anaerobic zone was 15. 34 L. In operating mode II , the volume of aerobic zone was 12. 56 L, and the volume of anaerobic zone was 12. 44 L. In operating mode III , the volume of aerobic zone was 15.42 L, and the volume of anaerobic zone was 9.58 L. Three operating modes expressed different volume loading of the reactor because of different aerobic/anaerobic zone. The results showed that the performance of ammonia nitrogen and phosphorus removal was a bit poor in operating mode I , the effluent nitrate nitrogen was higher in operating mode III compared with other modes, which brought the total nitrogen removal efficiency lower. The operating mode II was optimal for nitrogen and phosphorus removal. In operating mode II , the ammonia nitrogen removal efficiency was about 80. 63% , the volume loading rate of nitrogen removal was about 150. 27 g(m3 d)-1, and the COD removal efficiency was higher than 83.24%; the amounts of phosphorus release and uptake under anaerobic conditions were 7. 23 mg L-1 and 11. 93 mg L-1.

  18. Impact of batch, repeated-batch (with cell recycle and medium replacement) and continuous processes on the course and efficiency of aerobic thermophilic biodegradation of potato processing wastewater.

    PubMed

    Lasik, Małgorzata; Nowak, Jacek; Krzywonos, Małgorzata; Cibis, Edmund

    2010-05-01

    The aim of the study was to assess the course and efficiency of aerobic thermophilic treatment of a high-strength (COD=35gO(2)/l) effluent from potato processing. A comparative analysis was conducted of the treatment effects achieved using batch, repeated-batch (with cell recycle and medium replacement) and continuous treatment operations. The analysis consisted in (1) examining the extent of removal for the major parameters of the wastewater: COD, TOC, TN and TP (chemical oxygen demand, total organic carbon, total nitrogen and total phosphorus), and (2) determining the impact of oxygen deficit on the formation and assimilation of organic acids in the course of the three treatment operations. When use was made of the repeated-batch operation, the values of the COD and TOC removal rates were more than twice as high as those obtained with the continuous process, and more than five times as high as those obtained with the batch process.

  19. Aerobic Tennis.

    ERIC Educational Resources Information Center

    Stewart, Michael J.; Ahlschwede, Robert

    1989-01-01

    Increasing the aerobic nature of tennis drills in the physical education class may be necessary if tennis is to remain a part of the public school curriculum. This article gives two examples of drills that can be modified by teachers to increase activity level. (IAH)

  20. Natural light-micro aerobic condition for PSB wastewater treatment: a flexible, simple, and effective resource recovery wastewater treatment process.

    PubMed

    Lu, Haifeng; Han, Ting; Zhang, Guangming; Ma, Shanshan; Zhang, Yuanhui; Li, Baoming; Cao, Wei

    2017-03-13

    Photosynthetic bacteria (PSB) have two sets of metabolic pathways. They can degrade pollutants through light metabolic under light-anaerobic or oxygen metabolic pathways under dark-aerobic conditions. Both metabolisms function under natural light-microaerobic condition, which demands less energy input. This work investigated the characteristics of PSB wastewater treatment process under that condition. Results showed that PSB had very strong adaptability to chemical oxygen demand (COD) concentration; with F/M of 5.2-248.5 mg-COD/mg-biomass, the biomass increased three times and COD removal reached above 91.5%. PSB had both advantages of oxygen metabolism in COD removal and light metabolism in resource recovery under natural light-microaerobic condition. For pollutants' degradation, COD, total organic carbon, nitrogen, and phosphorus removal reached 96.2%, 91.0%, 70.5%, and 92.7%, respectively. For resource recovery, 74.2% of C in wastewater was transformed into biomass. Especially, coexistence of light and oxygen promote N recovery ratio to 70.9%, higher than with the other two conditions. Further, 93.7% of N-removed was synthesized into biomass. Finally, CO2 emission reduced by 62.6% compared with the traditional process. PSB wastewater treatment under this condition is energy-saving, highly effective, and environment friendly, and can achieve pollution control and resource recovery.

  1. Decolorization and biodegradation of Rubine GFL by microbial consortium GG-BL in sequential aerobic/microaerophilic process.

    PubMed

    Waghmode, Tatoba R; Kurade, Mayur B; Lade, Harshad S; Govindwar, Sanjay P

    2012-07-01

    This study represents the development of a new batch method by consortium GG-BL using two microbial cultures viz., Galactomyces geotrichum MTCC 1360 and Brevibacillus laterosporus MTCC 2298, by varying environmental conditions for the decolorization and biodegradation of Rubine GFL. Consortium was found to give better decolorization and degradation of Rubine GFL as compared to the individual microorganism at aerobic/microaerophilic process. The consortial metabolic activity of these strains lead to 100% decolorization of Rubine GFL (50 mg/L) within 30 h with significant reduction in chemical oxygen demand (79%) and total organic carbon (68%). Induction in the activities of laccase, veratryl alcohol oxidase, tyrosinase, azo reductase, and riboflavin reductase suggested their role in the decolorization process. Nondenaturing polyacrylamide gel electrophoresis analysis showed differential induction pattern of oxidoreductive enzymes during decolorization of the dye at different incubation temperatures. The degradation of Rubine GFL into different metabolites by individual organism and in consortium was confirmed using high performance thin layer chromatography, high performance liquid chromatography, Fourier transform infrared spectroscopy, and gas chromatography-mass spectroscopy analysis. Phytotoxicity studies revealed nontoxic nature of the metabolites of Rubine GFL.

  2. Full-scale demonstration of step feed concept for improving an anaerobic/anoxic/aerobic nutrient removal process.

    PubMed

    Ge, Shijian; Zhu, Yunpeng; Lu, Congcong; Wang, Shuying; Peng, Yongzhen

    2012-09-01

    A small wastewater treatment plant (WWTP) failed to meet effluent requirements of the first-A discharge standard in China, with the anaerobic/anoxic/oxic (A/A/O) process treating municipal and partial industrial wastewater. Thus an A/O step feed process (Anoxic/oxic/anoxic/oxic/anoxic/oxic) with floating plastic carriers in aerobic units was proposed to improve nutrient removal within the existing WWTP. Four main reform strategies were applied: (1) the original influent was divided into three streams which led into corresponding anoxic units; (2) floating plastic carriers were placed in the second and third oxic units; (3) nitrified liquid recycling was omitted; (4) channel shapes and sizes were adjusted between adjacent units to prevent backflow. After these modifications were implemented, the total nitrogen and phosphorus concentrations in the effluent were reduced from 20.8 to 14.2mg/L, and from 1.89 to 0.57 mg/L, respectively. Moreover, annual electricity consumption in the WWTP was reduced by 245 MWh as a result of these modifications.

  3. Presence of Aerobic Microorganisms, Enterobacteriaceae and Salmonella in the Shell Egg Processing Environment

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sanitation is vital to providing safe, healthy food to consumers. Understanding the degree to which microorganisms persist on specific equipment or locations contributes to developing effective sanitation programs. Certain microbial populations may be used to determine areas within a processing pl...

  4. [Microbiological processes at the interface of aerobic and anaerobic waters in the deep-water zone of the Black Sea].

    PubMed

    Pimenov, N V; Rusanov, I I; Iusupov, S K; Fridrich, J; Lein, A Iu; Wehrli, B; Ivanov, M V

    2000-01-01

    Chemical and key microbiological processes (assimilation of carbon dioxide, oxidation and formation of methane, and sulfate reduction) occurring at the boundary between the aerobic-anaerobic interface in the deep-water zone of the Black Sea were investigated. Measurements were taken at depths from 90 to 300 m at intervals of 5-10 m. The integral rate of the dark assimilation of carbon dioxide varied from 120 to 207 mg C/(m2 day) with a maximum at the boundary of cyclonic currents. The organic matter (OM) formed from methane comprised less than 5% of the OM formed from carbon dioxide. A comparison between the rates of methane oxidation and methane production suggests that methane that is oxidized at depths from 100 to 300 m was formed in deeper water horizons. The maximum rate of sulfate reduction (1230 mg S/(m2 day)) was observed in the western halistatic region, and the minimum rate (490 mg S/(m2 day)), in the eastern halistatic region. The average rate of hydrogen sulfide production measured at three deep-sea stations amounted to 755 mg S/(m2 day), or 276 g S/(m2 year).

  5. Phosphorus removal and greenhouse gas N2O emission in a lime-induced aerobic sludge granule process.

    PubMed

    Wu, X L; Guan, Y T; Zhang, X; Huang, X; Qian, Y

    2002-06-01

    Aerobic sludge granulation was achieved in an activated sludge process continuously fed with lime (Ca2+ 100 mg l(-1) influent) every other day. Eighteen days after lime addition, activated sludge granules with the size of 0.5-2.2 mm were formed, which occupied 10-25% of total sludge volume. Sludge volume index (SVI) was reduced to an average of 50 ml g(-1), which increased average sludge concentration to 3.6-5.0 g VSS l(-1), 1.6-2.1 times of that of control. Greenhouse gas N2O emission was also significantly reduced: N2O concentration from the lime-addition reactor was 5-15 ppmv, 47-61% of that of control, Effluent PO4-P concentration was generally lower than 1 mg l(-1) when average influent PO4-P concentration was 6.07-6.37 mg l(-1). Total phosphorus (TP) and total nitrogen (TN) removal efficiencies were around 89.6% and 14.5-16.1%, over 3.5 and 1 times higher than those of control, respectively. COD removal rate in the lime-addition reactor was 2.05-2.48 kg COD m(-3) d(-1), higher than 1.34-1.61 kg COD m(-3) d(-1) in the control.

  6. Effect of sludge age on methanogenic and glycogen accumulating organisms in an aerobic granular sludge process fed with methanol and acetate

    PubMed Central

    Pronk, M; Abbas, B; Kleerebezem, R; van Loosdrecht, M C M

    2015-01-01

    The influence of sludge age on granular sludge formation and microbial population dynamics in a methanol- and acetate-fed aerobic granular sludge system operated at 35°C was investigated. During anaerobic feeding of the reactor, methanol was initially converted to methane by methylotrophic methanogens. These methanogens were able to withstand the relatively long aeration periods. Lowering the anaerobic solid retention time (SRT) from 17 to 8 days enabled selective removal of the methanogens and prevented unwanted methane formation. In absence of methanogens, methanol was converted aerobically, while granule formation remained stable. At high SRT values (51 days), γ-Proteobacteria were responsible for acetate removal through anaerobic uptake and subsequent aerobic growth on storage polymers formed [so called metabolism of glycogen-accumulating organisms (GAO)]. When lowering the SRT (24 days), Defluviicoccus-related organisms (cluster II) belonging to the α-Proteobacteria outcompeted acetate consuming γ-Proteobacteria at 35°C. DNA from the Defluviicoccus-related organisms in cluster II was not extracted by the standard DNA extraction method but with liquid nitrogen, which showed to be more effective. Remarkably, the two GAO types of organisms grew separately in two clearly different types of granules. This work further highlights the potential of aerobic granular sludge systems to effectively influence the microbial communities through sludge age control in order to optimize the wastewater treatment processes. PMID:26059251

  7. Remediation of a winery wastewater combining aerobic biological oxidation and electrochemical advanced oxidation processes.

    PubMed

    Moreira, Francisca C; Boaventura, Rui A R; Brillas, Enric; Vilar, Vítor J P

    2015-05-15

    Apart from a high biodegradable fraction consisting of organic acids, sugars and alcohols, winery wastewaters exhibit a recalcitrant fraction containing high-molecular-weight compounds as polyphenols, tannins and lignins. In this context, a winery wastewater was firstly subjected to a biological oxidation to mineralize the biodegradable fraction and afterwards an electrochemical advanced oxidation process (EAOP) was applied in order to mineralize the refractory molecules or transform them into simpler ones that can be further biodegraded. The biological oxidation led to above 97% removals of dissolved organic carbon (DOC), chemical oxygen demand (COD) and 5-day biochemical oxygen demand (BOD5), but was inefficient on the degradation of a bioresistant fraction corresponding to 130 mg L(-1) of DOC, 380 mg O2 L(-1) of COD and 8.2 mg caffeic acid equivalent L(-1) of total dissolved polyphenols. Various EAOPs such as anodic oxidation with electrogenerated H2O2 (AO-H2O2), electro-Fenton (EF), UVA photoelectro-Fenton (PEF) and solar PEF (SPEF) were then applied to the recalcitrant effluent fraction using a 2.2 L lab-scale flow plant containing an electrochemical cell equipped with a boron-doped diamond (BDD) anode and a carbon-PTFE air-diffusion cathode and coupled to a photoreactor with compound parabolic collectors (CPCs). The influence of initial Fe(2+) concentration and current density on the PEF process was evaluated. The relative oxidative ability of EAOPs increased in the order AO-H2O2 < EF < PEF ≤ SPEF. The SPEF process using an initial Fe(2+) concentration of 35 mg L(-1), current density of 25 mA cm(-2), pH of 2.8 and 25 °C reached removals of 86% on DOC and 68% on COD after 240 min, regarding the biologically treated effluent, along with energy consumptions of 45 kWh (kg DOC)(-1) and 5.1 kWh m(-3). After this coupled treatment, color, odor, COD, BOD5, NH4(+), NO3(-) and SO4(2-) parameters complied with the legislation targets and, in addition, a total

  8. Large Deviations for Processes with Independent Increments.

    DTIC Science & Technology

    1984-10-01

    generating function of the increments exists and thus the sample paths of such stochastic processes lie in the space of functions of bounded variation . The...BV[O,1], the space of functions of bounded variation and the topology is that of weak*-convergence. Varadhan (1966) studied the LDP for similar...increments and no Gaussian component which are considered as elements of BV[0,1], the space of functions of bounded variation . The final section

  9. Black and White race differences in aerobic capacity, muscle fiber type, and their influence on metabolic processes.

    PubMed

    Ceaser, Tyrone; Hunter, Gary

    2015-05-01

    Obesity is a known risk factor for cardiometabolic disease. Increasing aerobic capacity (VO2max) reduces adiposity, maintains weight, and reduces the risk of developing obesity and cardiometabolic disease. Two major determinants of aerobic capacity are the metabolic properties specific to a particular muscle fiber type and the capacity of the cardiorespiratory system to deliver nutrient-rich content to the muscle. Recent research suggests that some race/ethnic groups, particularly non-Hispanic Black subjects, are predisposed to a reduced VO2max by way of muscle fiber type. Combined with insufficient physical activity, these characteristics place non-Hispanic Black subjects at an increased risk for obesity and other adverse health outcomes when compared with other race/ethnic groups. The purpose of this review was to suggest a model for explaining how skeletal muscle fiber type may contribute to reduced aerobic capacity and obesity among non-Hispanic Black subjects. Our review indicates that metabolic properties of type II skeletal muscle (e.g. reduced oxidative capacity, capillary density) are related to various cardiometabolic diseases. Based on the review, non-Hispanic Black subjects appear to have a lower maximal aerobic capacity and a greater percentage of type II skeletal muscle fibers. Combined with reduced energy expenditure and reduced hemoglobin concentration, non-Hispanic Black subjects may be inherently predisposed to a reduced maximal aerobic capacity compared with non-Hispanic White subjects, thereby increasing the risk for obesity and related metabolic diseases.

  10. Effect of process design and operating parameters on aerobic methane oxidation in municipal WWTPs.

    PubMed

    Daelman, Matthijs R J; Van Eynde, Tamara; van Loosdrecht, Mark C M; Volcke, Eveline I P

    2014-12-01

    Methane is a potent greenhouse gas and its emission from municipal wastewater treatment plants (WWTPs) should be prevented. One way to do this is to promote the biological conversion of dissolved methane over stripping in aeration tanks. In this study, the well-established Activated Sludge Model n°1 (ASM1) and Benchmark Simulation Model n°1 (BSM1) were extended to study the influence of process design and operating parameters on biological methane oxidation. The aeration function used in BSM 1 was upgraded to more accurately describe gas-liquid transfer of oxygen and methane in aeration tanks equipped with subsurface aeration. Dissolved methane could be effectively removed in an aeration tank at an aeration rate that is in agreement with optimal effluent quality. Subsurface bubble aeration proved to be better than surface aeration, while a CSTR configuration was superior to plug flow conditions in avoiding methane emissions. The conversion of methane in the activated sludge tank benefits from higher methane concentrations in the WWTP's influent. Finally, if an activated sludge tank is aerated with methane containing off-gas, a limited amount of methane is absorbed and converted in the mixed liquor. This knowledge helps to stimulate the methane oxidizing capacity of activated sludge in order to abate methane emissions from wastewater treatment to the atmosphere.

  11. Decolorization of anthraquinone dye intermediate and its accelerating effect on reduction of azo acid dyes by Sphingomonas xenophaga in anaerobic-aerobic process.

    PubMed

    Lu, Hong; Zhou, Jiti; Wang, Jing; Ai, Haixin; Zheng, Chunli; Yang, Yusuo

    2008-09-01

    Decolorization of 1-aminoanthraquinone-2-sulfonic acid (ASA-2) and its accelerating effect on the reduction of azo acid dyes by Sphingomonas xenophaga QYY were investigated. The study showed that ASA-2 could be efficiently decolorized by strain QYY under aerobic conditions according to the analysis of total organic carbon removal and UV-VIS spectra changes. Moreover, strain QYY was able to reduce azo acid dyes under anaerobic conditions. The effects of various operating conditions such as carbon sources, temperature, and pH on the reduction rate were studied. It was demonstrated that ASA-2 used as a redox mediator could accelerate the reduction process. Consequently the reduction of azo acid dyes mediated by ASA-2 and the decolorization of ASA-2 with strain QYY could be achieved in an anaerobic-aerobic process.

  12. Process for producing large grain cadmium telluride

    DOEpatents

    Hasoon, F.S.; Nelson, A.J.

    1996-01-16

    A process is described for producing a cadmium telluride polycrystalline film having grain sizes greater than about 20 {micro}m. The process comprises providing a substrate upon which cadmium telluride can be deposited and placing that substrate within a vacuum chamber containing a cadmium telluride effusion cell. A polycrystalline film is then deposited on the substrate through the steps of evacuating the vacuum chamber to a pressure of at least 10{sup {minus}6} torr.; heating the effusion cell to a temperature whereat the cell releases stoichiometric amounts of cadmium telluride usable as a molecular beam source for growth of grains on the substrate; heating the substrate to a temperature whereat a stoichiometric film of cadmium telluride can be deposited; and releasing cadmium telluride from the effusion cell for deposition as a film on the substrate. The substrate then is placed in a furnace having an inert gas atmosphere and heated for a sufficient period of time at an annealing temperature whereat cadmium telluride grains on the substrate grow to sizes greater than about 20 {micro}m.

  13. Anaerobic/aerobic treatment of a petrochemical wastewater from two aromatic transformation processes by fluidized bed reactors.

    PubMed

    Estrada-Arriaga, Edson B; Ramirez-Camperos, Esperanza; Moeller-Chavez, Gabriela E; García-Sanchez, Liliana

    2012-01-01

    An integrated fluidized bed reactor (FBR) has been employed as the treatment for petrochemical industry wastewaters with high organic matter and aromatic compounds, under anaerobic and aerobic conditions. The system was operated at hydraulic residence time (HRT) of 2.7 and 2.2 h in the anaerobic and aerobic reactor, respectively. The degree of fluidization in the beds was 30%. This system showed a high performance on the removal of organic matter and aromatic compounds. At different organic loading rates (OLR), the chemical oxygen demand (COD) removal in the anaerobic reactor was close to 85% and removals of the COD up to 94% were obtained in the aerobic reactor. High removals of benzene, toluene, ethylbenzene, xylenes, styrene, 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene and naphthalene were achieved in this study.

  14. The effectiveness of flocculants on inorganic and metallic species removal during aerobic digestion of wastewater from poultry processing plant

    Technology Transfer Automated Retrieval System (TEKTRAN)

    : Large amount of water is used for processing of our food supplies, especially in meat processing plants. The resulting amount of wastewater cannot be discarded freely back into natural settings due to regulatory mandates, whether the sinks would be rivers, ponds, or other natural systems. These wa...

  15. The effectiveness of flocculants on inorganic and metallic species removal during aerobic digestion of wastewater from poultry processing plant

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Large amount of water is used for processing of our food supplies, especially in meat processing plants. The resulting amount of wastewater cannot be discarded freely back into natural settings due to regulatory mandates, whether the sinks would be rivers, ponds, or other natural systems. These wast...

  16. Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes.

    PubMed

    de Groot, Marco J L; Daran-Lapujade, Pascale; van Breukelen, Bas; Knijnenburg, Theo A; de Hulster, Erik A F; Reinders, Marcel J T; Pronk, Jack T; Heck, Albert J R; Slijper, Monique

    2007-11-01

    Saccharomyces cerevisiae is unique among yeasts in its ability to grow rapidly in the complete absence of oxygen. S. cerevisiae is therefore an ideal eukaryotic model to study physiological adaptation to anaerobiosis. Recent transcriptome analyses have identified hundreds of genes that are transcriptionally regulated by oxygen availability but the relevance of this cellular response has not been systematically investigated at the key control level of the proteome. Therefore, the proteomic response of S. cerevisiae to anaerobiosis was investigated using metabolic stable-isotope labelling in aerobic and anaerobic glucose-limited chemostat cultures, followed by relative quantification of protein expression. Using independent replicate cultures and stringent statistical filtering, a robust dataset of 474 quantified proteins was generated, of which 249 showed differential expression levels. While some of these changes were consistent with previous transcriptome studies, many of the responses of S. cerevisiae to oxygen availability were, to our knowledge, previously unreported. Comparison of transcriptomes and proteomes from identical cultivations yielded strong evidence for post-transcriptional regulation of key cellular processes, including glycolysis, amino-acyl-tRNA synthesis, purine nucleotide synthesis and amino acid biosynthesis. The use of chemostat cultures provided well-controlled and reproducible culture conditions, which are essential for generating robust datasets at different cellular information levels. Integration of transcriptome and proteome data led to new insights into the physiology of anaerobically growing yeast that would not have been apparent from differential analyses at either the mRNA or protein level alone, thus illustrating the power of multi-level studies in yeast systems biology.

  17. Aerobic Anoxygenic Phototrophic Bacteria

    PubMed Central

    Yurkov, Vladimir V.; Beatty, J. Thomas

    1998-01-01

    The aerobic anoxygenic phototrophic bacteria are a relatively recently discovered bacterial group. Although taxonomically and phylogenetically heterogeneous, these bacteria share the following distinguishing features: the presence of bacteriochlorophyll a incorporated into reaction center and light-harvesting complexes, low levels of the photosynthetic unit in cells, an abundance of carotenoids, a strong inhibition by light of bacteriochlorophyll synthesis, and the inability to grow photosynthetically under anaerobic conditions. Aerobic anoxygenic phototrophic bacteria are classified in two marine (Erythrobacter and Roseobacter) and six freshwater (Acidiphilium, Erythromicrobium, Erythromonas, Porphyrobacter, Roseococcus, and Sandaracinobacter) genera, which phylogenetically belong to the α-1, α-3, and α-4 subclasses of the class Proteobacteria. Despite this phylogenetic information, the evolution and ancestry of their photosynthetic properties are unclear. We discuss several current proposals for the evolutionary origin of aerobic phototrophic bacteria. The closest phylogenetic relatives of aerobic phototrophic bacteria include facultatively anaerobic purple nonsulfur phototrophic bacteria. Since these two bacterial groups share many properties, yet have significant differences, we compare and contrast their physiology, with an emphasis on morphology and photosynthetic and other metabolic processes. PMID:9729607

  18. Effects of carbon dioxide on the fate of Listeria monocytogenes, of aerobic bacteria and on the development of spoilage in minimally processed fresh endive.

    PubMed

    Carlin, F; Nguyen-the, C; Abreu Da Silva, A; Cochet, C

    1996-09-01

    Minimally processed fresh broad-leaved endive (Cichorium endivia L.) were stored at 3 and 10 degrees C in modified atmospheres containing air, 10% CO2/10% O2, 30% CO2/10% O2, and 50% CO2/10% O2. The effects of these modified atmospheres on the fate of both aerobic bacteria and three strains of Listeria monocytogenes, was investigated. Increases in CO2 concentrations significantly reduced the growth of the aerobic microflora. The best preservation of the visual quality occurred on endive leaves stored in 10% CO2/10% O2, whereas leaves stored in 30% CO2/10% O2 and 50% CO2/10% O2, and to a lesser extent in air, showed extensive spoilage after storage. Listeria monocytogenes was slightly affected at 3 degrees C by the modified atmospheres, as compared to air. At 10 degrees C, results varied between replicate experiments, but L. monocytogenes generally grew better as the CO2 concentration was increased. The three test strains behaved in a similar way. In conclusion, among the modified atmospheres tested, a modified atmosphere containing 10% CO2/10% O2 resulted in improved visual quality of minimally processed fresh endive, without a marked effect on the growth of the aerobic microflora or of L. monocytogenes.

  19. Effect of aerobic pre-treatment on hydrogen and methane production in a two-stage anaerobic digestion process using food waste with different compositions.

    PubMed

    Rafieenia, Razieh; Girotto, Francesca; Peng, Wei; Cossu, Raffaello; Pivato, Alberto; Raga, Roberto; Lavagnolo, Maria Cristina

    2017-01-01

    Aerobic pre-treatment was applied prior to two-stage anaerobic digestion process. Three different food wastes samples, namely carbohydrate rich, protein rich and lipid rich, were prepared as substrates. Effect of aerobic pre-treatment on hydrogen and methane production was studied. Pre-aeration of substrates showed no positive impact on hydrogen production in the first stage. All three categories of pre-aerated food wastes produced less hydrogen compared to samples without pre-aeration. In the second stage, methane production increased for aerated protein rich and carbohydrate rich samples. In addition, the lag phase for carbohydrate rich substrate was shorter for aerated samples. Aerated protein rich substrate yielded the best results among substrates for methane production, with a cumulative production of approximately 351ml/gVS. With regard to non-aerated substrates, lipid rich was the best substrate for CH4 production (263ml/gVS). Pre-aerated P substrate was the best in terms of total energy generation which amounted to 9.64kJ/gVS. This study revealed aerobic pre-treatment to be a promising option for use in achieving enhanced substrate conversion efficiencies and CH4 production in a two-stage AD process, particularly when the substrate contains high amounts of proteins.

  20. Microbiology and potential applications of aerobic methane oxidation coupled to denitrification (AME-D) process: A review.

    PubMed

    Zhu, Jing; Wang, Qian; Yuan, Mengdong; Tan, Giin-Yu Amy; Sun, Faqian; Wang, Cheng; Wu, Weixiang; Lee, Po-Heng

    2016-03-01

    Aerobic methane oxidation coupled to denitrification (AME-D) is an important link between the global methane and nitrogen cycles. This mini-review updates discoveries regarding aerobic methanotrophs and denitrifiers, as a prelude to spotlight the microbial mechanism and the potential applications of AME-D. Until recently, AME-D was thought to be accomplished by a microbial consortium where denitrifying bacteria utilize carbon intermediates, which are excreted by aerobic methanotrophs, as energy and carbon sources. Potential carbon intermediates include methanol, citrate and acetate. This mini-review presents microbial thermodynamic estimations and postulates that methanol is the ideal electron donor for denitrification, and may serve as a trophic link between methanotrophic bacteria and denitrifiers. More excitingly, new discoveries have revealed that AME-D is not only confined to the conventional synergism between methanotrophic bacteria and denitrifiers. Specifically, an obligate aerobic methanotrophic bacterium, Methylomonas denitrificans FJG1, has been demonstrated to couple partial denitrification with methane oxidation, under hypoxia conditions, releasing nitrous oxide as a terminal product. This finding not only substantially advances the understanding of AME-D mechanism, but also implies an important but unknown role of aerobic methanotrophs in global climate change through their influence on both the methane and nitrogen cycles in ecosystems. Hence, further investigation on AME-D microbiology and mechanism is essential to better understand global climate issues and to develop niche biotechnological solutions. This mini-review also presents traditional microbial techniques, such as pure cultivation and stable isotope probing, and powerful microbial techniques, such as (meta-) genomics and (meta-) transcriptomics, for deciphering linked methane oxidation and denitrification. Although AME-D has immense potential for nitrogen removal from wastewater, drinking

  1. Modeling a Dry Etch Process for Large-Area Devices

    SciTech Connect

    Buss, R.J.; Hebner, G.A.; Ruby, D.S.; Yang, P.

    1999-07-28

    There has been considerable interest in developing dry processes which can effectively replace wet processing in the manufacture of large area photovoltaic devices. Environmental and health issues are a driver for this activity because wet processes generally increase worker exposure to toxic and hazardous chemicals and generate large volumes of liquid hazardous waste. Our work has been directed toward improving the performance of screen-printed solar cells while using plasma processing to reduce hazardous chemical usage.

  2. Current Large Deviations for Asymmetric Exclusion Processes with Open Boundaries

    NASA Astrophysics Data System (ADS)

    Bodineau, T.; Derrida, B.

    2006-04-01

    We study the large deviation functional of the current for the Weakly Asymmetric Simple Exclusion Process in contact with two reservoirs. We compare this functional in the large drift limit to the one of the Totally Asymmetric Simple Exclusion Process, in particular to the Jensen-Varadhan functional. Conjectures for generalizing the Jensen-Varadhan functional to open systems are also stated.

  3. Effects of dissolved oxygen on performance and microbial community structure in a micro-aerobic hydrolysis sludge in situ reduction process.

    PubMed

    Niu, Tianhao; Zhou, Zhen; Shen, Xuelian; Qiao, Weimin; Jiang, Lu-Man; Pan, Wei; Zhou, Jijun

    2016-03-01

    A sludge process reduction activated sludge (SPRAS), with a sludge process reduction module composed of a micro-aerobic tank and a settler positioned before conventional activated sludge process, showed good performance of pollutant removal and sludge reduction. Two SPRAS systems were operated to investigate effects of micro-aeration on sludge reduction performance and microbial community structure. When dissolved oxygen (DO) concentration in the micro-aerobic tank decreased from 2.5 (SPH) to 0.5 (SPL) mg/L, the sludge reduction efficiency increased from 42.9% to 68.3%. Compared to SPH, activated sludge in SPL showed higher contents of extracellular polymeric substances and dissolved organic matter. Destabilization of floc structure in the settler, and cell lysis in the sludge process reduction module were two major reasons for sludge reduction. Illumina-MiSeq sequencing showed that microbial diversity decreased under high DO concentration. Proteobacteria, Bacteroidetes and Chloroflexi were the most abundant phyla in the SPRAS. Specific comparisons down to the class and genus level showed that fermentative, predatory and slow-growing bacteria in SPL community were more abundant than in SPH. The results revealed that micro-aeration in the SPRAS improved hydrolysis efficiency and enriched fermentative and predatory bacteria responsible for sludge reduction.

  4. Large-Scale Graph Processing Analysis using Supercomputer Cluster

    NASA Astrophysics Data System (ADS)

    Vildario, Alfrido; Fitriyani; Nugraha Nurkahfi, Galih

    2017-01-01

    Graph implementation is widely use in various sector such as automotive, traffic, image processing and many more. They produce graph in large-scale dimension, cause the processing need long computational time and high specification resources. This research addressed the analysis of implementation large-scale graph using supercomputer cluster. We impelemented graph processing by using Breadth-First Search (BFS) algorithm with single destination shortest path problem. Parallel BFS implementation with Message Passing Interface (MPI) used supercomputer cluster at High Performance Computing Laboratory Computational Science Telkom University and Stanford Large Network Dataset Collection. The result showed that the implementation give the speed up averages more than 30 times and eficiency almost 90%.

  5. Combined mesophilic anaerobic and thermophilic aerobic digestion process for high-strength food wastewater to increase removal efficiency and reduce sludge discharge.

    PubMed

    Jang, H M; Park, S K; Ha, J H; Park, J M

    2014-01-01

    In this study, a process that combines the mesophilic anaerobic digestion (MAD) process with thermophilic aerobic digestion (TAD) for high-strength food wastewater (FWW) treatment was developed to examine the removal of organic matter and methane production. All effluent discharged from the MAD process was separated into solid and liquid portions. The liquid part was discarded and the sludge part was passed to the TAD process for further degradation. Then, the digested sludge from the TAD process was recycled back to the MAD unit to achieve low sludge discharge from the combined process. The reactor combination was operated in two phases: during Phase I, 40 d of total hydraulic retention time (HRT) was applied; during Phase II, 20 d was applied. HRT of the TAD process was fixed at 5 d. For a comparison, a control process (single-stage MAD) was operated with the same HRTs of the combined process. Our results indicated that the combined process showed over 90% total solids, volatile solids and chemical oxygen demand removal efficiencies. In addition, the combined process showed a significantly higher methane production rate than that of the control process. Consequently, the experimental data demonstrated that the combined MAD-TAD process was successfully employed for high-strength FWW treatment with highly efficient organic matter reduction and methane production.

  6. The Analysis of a Microbial Community in the UV/O3-Anaerobic/Aerobic Integrated Process for Petrochemical Nanofiltration Concentrate (NFC) Treatment by 454-Pyrosequencing.

    PubMed

    Wei, Chao; He, Wenjie; Wei, Li; Li, Chunying; Ma, Jun

    2015-01-01

    In this study, high-throughput pyrosequencing was applied on the analysis of the microbial community of activated sludge and biofilm in a lab-scale UV/O3- anaerobic/aerobic (A/O) integrated process for the treatment of petrochemical nanofiltration concentrate (NFC) wastewater. NFC is a type of saline wastewater with low biodegradability. From the anaerobic activated sludge (Sample A) and aerobic biofilm (Sample O), 59,748 and 51,231 valid sequence reads were obtained, respectively. The dominant phylotypes related to the metabolism of organic compounds, polycyclic aromatic hydrocarbon (PAH) biodegradation, assimilation of carbon from benzene, and the biodegradation of nitrogenous organic compounds were detected as genus Clostridium, genera Pseudomonas and Stenotrophomonas, class Betaproteobacteria, and genus Hyphomicrobium. Furthermore, the nitrite-oxidising bacteria Nitrospira, nitrite-reducing and sulphate-oxidising bacteria (NR-SRB) Thioalkalivibrio were also detected. In the last twenty operational days, the total Chemical Oxygen Demand (COD) and Total Organic Carbon (TOC) removal efficiencies on average were 64.93% and 62.06%, respectively. The removal efficiencies of ammonia nitrogen and Total Nitrogen (TN) on average were 90.51% and 75.11% during the entire treatment process.

  7. The Analysis of a Microbial Community in the UV/O3-Anaerobic/Aerobic Integrated Process for Petrochemical Nanofiltration Concentrate (NFC) Treatment by 454-Pyrosequencing

    PubMed Central

    Wei, Chao; He, Wenjie; Wei, Li; Li, Chunying; Ma, Jun

    2015-01-01

    In this study, high-throughput pyrosequencing was applied on the analysis of the microbial community of activated sludge and biofilm in a lab-scale UV/O3- anaerobic/aerobic (A/O) integrated process for the treatment of petrochemical nanofiltration concentrate (NFC) wastewater. NFC is a type of saline wastewater with low biodegradability. From the anaerobic activated sludge (Sample A) and aerobic biofilm (Sample O), 59,748 and 51,231 valid sequence reads were obtained, respectively. The dominant phylotypes related to the metabolism of organic compounds, polycyclic aromatic hydrocarbon (PAH) biodegradation, assimilation of carbon from benzene, and the biodegradation of nitrogenous organic compounds were detected as genus Clostridium, genera Pseudomonas and Stenotrophomonas, class Betaproteobacteria, and genus Hyphomicrobium. Furthermore, the nitrite-oxidising bacteria Nitrospira, nitrite-reducing and sulphate-oxidising bacteria (NR-SRB) Thioalkalivibrio were also detected. In the last twenty operational days, the total Chemical Oxygen Demand (COD) and Total Organic Carbon (TOC) removal efficiencies on average were 64.93% and 62.06%, respectively. The removal efficiencies of ammonia nitrogen and Total Nitrogen (TN) on average were 90.51% and 75.11% during the entire treatment process. PMID:26461260

  8. Nonterrestrial material processing and manufacturing of large space systems

    NASA Technical Reports Server (NTRS)

    Vontiesenhausen, G. F.

    1978-01-01

    An attempt is made to provide pertinent and readily usable information on the extraterrestrial processing of materials and manufacturing of components and elements of these planned large space systems from preprocessed lunar materials which are made available at a processing and manufacturing site in space. Required facilities, equipment, machinery, energy and manpower are defined.

  9. Phase transitions in large deviations of reset processes

    NASA Astrophysics Data System (ADS)

    Harris, Rosemary J.; Touchette, Hugo

    2017-03-01

    We study the large deviations of additive quantities, such as energy or current, in stochastic processes with intermittent reset. Via a mapping from a discrete-time reset process to the Poland–Scheraga model for DNA denaturation, we derive conditions for observing first-order or continuous dynamical phase transitions in the fluctuations of such quantities and confirm these conditions on simple random walk examples. These results apply to reset Markov processes, but also show more generally that subleading terms in generating functions can lead to non-analyticities in large deviation functions of ‘compound processes’ or ‘random evolutions’ switching stochastically between two or more subprocesses.

  10. Characterization of organic particulates present in milk factory process waters used for reuse along with aerobically digested effluent wastewater.

    PubMed

    Verheyen, Vincent; Cruickshank, Alicia; Wild, Karl; Heaven, Michael W; McGee, Rachel; Watkins, Mark; Nash, David

    2011-01-01

    Wastewater from a dairy processor is being reused and recycled both within the plant and for irrigation. Flash pyrolysis GC-MS was used to examine nitrogen and phenol containing compounds (M.W.=35 to 450 g/mol) in the particulate fraction of the milk condensate, combined clean wastewater and aerobic bioreactor effluent. For comparison, the particulates were also prepared for standard GC-MS analyses using conventional solvent extraction methods. Compounds detected by pyrolysis GC-MS were found mostly in the bioreactor with the amino acid arginine (220 mg/kg) and the amino acid derivative 1-methyl-5-oxo-L-proline methyl ester (130 mg/kg) found at the highest concentrations. In comparison, sterols detected in the effluent were found at higher concentrations when using solvent extraction indicating some degradation with pyrolysis GC-MS. However, with few exceptions, particulates were generally found not to act as passive collectors capable of concentrating less water soluble chemicals.

  11. Effects of organic loading rates on reactor performance and microbial community changes during thermophilic aerobic digestion process of high-strength food wastewater.

    PubMed

    Jang, Hyun Min; Lee, Jae Won; Ha, Jeong Hyub; Park, Jong Moon

    2013-11-01

    To evaluate the applicability of single-stage thermophilic aerobic digestion (TAD) process treating high-strength food wastewater (FWW), TAD process was operated at four organic loading rates (OLRs) from 9.2 to 37.2 kg COD/m(3)d. The effects of OLRs on microbial community changes were also examined. The highest volumetric removal rate (13.3 kg COD/m(3)d) and the highest thermo-stable protease activity (0.95 unit/mL) were detected at OLR=18.6 kg COD/m(3)d. Denaturing gradient gel electrophoresis (DGGE) profiles and quantitative PCR (qPCR) results showed significant microbial community shifts in response to changes in OLR. In particular, DGGE and phylogenetic analysis demonstrate that the presence of Bacillus sp. (phylum of Firmicutes) was strongly correlated with efficient removal of organic particulates from high-strength food wastewater.

  12. Teaching Aerobic Fitness Concepts.

    ERIC Educational Resources Information Center

    Sander, Allan N.; Ratliffe, Tom

    2002-01-01

    Discusses how to teach aerobic fitness concepts to elementary students. Some of the K-2 activities include location, size, and purpose of the heart and lungs; the exercise pulse; respiration rate; and activities to measure aerobic endurance. Some of the 3-6 activities include: definition of aerobic endurance; heart disease risk factors;…

  13. Aerobic rice mechanization: techniques for crop establishment

    NASA Astrophysics Data System (ADS)

    Khusairy, K. M.; Ayob, H.; Chan, C. S.; Fauzi, M. I. Mohamed; Mohamad Fakhrul, Z. O.; Shahril Shah, G. S. M.; Azlan, O.; Rasad, M. A.; Hashim, A. M.; Arshad, Z.; E, E. Ibrahim; Saifulizan, M. N.

    2015-12-01

    Rice being the staple food crops, hundreds of land races in it makes the diversity of rice crops. Aerobic rice production was introduced which requires much less water input to safeguard and sustain the rice production and conserve water due to decreasing water resources, climatic changes and competition from urban and industrial users. Mechanization system plays an important role for the success of aerobic rice cultivation. All farming activities for aerobic rice production are run on aerobic soil conditions. Row seeder mechanization system is developed to replace conventional seeding technique on the aerobic rice field. It is targeted for small and the large scale aerobic rice farmers. The aero - seeder machine is used for the small scale aerobic rice field, while the accord - seeder is used for the large scale aerobic rice field. The use of this mechanization machine can eliminate the tedious and inaccurate seeding operations reduce labour costs and increases work rate. The machine is easy to operate and it can increase crop establishment rate. It reduce missing hill, increasing planting and crop with high yield can be produce. This machine is designed for low costs maintenance and it is easy to dismantle and assemble during maintenance and it is safe to be used.

  14. Aerobic glycolysis and lymphocyte transformation

    PubMed Central

    Hume, David A.; Radik, Judith L.; Ferber, Ernst; Weidemann, Maurice J.

    1978-01-01

    1. The role of enhanced aerobic glycolysis in the transformation of rat thymocytes by concanavalin A has been investigated. Concanavalin A addition doubled [U-14C]glucose uptake by rat thymocytes over 3h and caused an equivalent increased incorporation into protein, lipids and RNA. A disproportionately large percentage of the extra glucose taken up was converted into lactate, but concanavalin A also caused a specific increase in pyruvate oxidation, leading to an increase in the percentage contribution of glucose to the respiratory fuel. 2. Acetoacetate metabolism, which was not affected by concanavalin A, strongly suppressed pyruvate oxidation in the presence of [U-14C]glucose, but did not prevent the concanavalin A-induced stimulation of this process. Glucose uptake was not affected by acetoacetate in the presence or absence of concanavalin A, but in each case acetoacetate increased the percentage of glucose uptake accounted for by lactate production. 3. [3H]Thymidine incorporation into DNA in concanavalin A-treated thymocyte cultures was sensitive to the glucose concentration in the medium in a biphasic manner. Very low concentrations of glucose (25μm) stimulated DNA synthesis half-maximally, but maximum [3H]thymidine incorporation was observed only when the glucose concentration was raised to 1mm. Lactate addition did not alter the sensitivity of [3H]-thymidine uptake to glucose, but inosine blocked the effect of added glucose and strongly inhibited DNA synthesis. 4. It is suggested that the major function of enhanced aerobic glycolysis in transforming lymphocytes is to maintain higher steady-state amounts of glycolytic intermediates to act as precursors for macromolecule synthesis. PMID:310305

  15. High Aerobic Capacity Mitigates Changes in the Plasma Metabolomic Profile Associated with Aging.

    PubMed

    Falegan, Oluyemi S; Vogel, Hans J; Hittel, Dustin S; Koch, Lauren G; Britton, Steven L; Hepple, Russ T; Shearer, Jane

    2017-02-03

    Advancing age is associated with declines in maximal oxygen consumption. Declines in aerobic capacity not only contribute to the aging process but also are an independent risk factor for morbidity, cardiovascular disease, and all-cause mortality. Although statistically convincing, the relationships between aerobic capacity, aging, and disease risk remain largely unresolved. To this end, we employed sensitive, system-based metabolomics approach to determine whether enhanced aerobic capacity could mitigate some of the changes seen in the plasma metabolomic profile associated with aging. Metabolomic profiles of plasma samples obtained from young (13 month) and old (26 month) rats bred for low (LCR) or high (HCR) running capacity using proton nuclear magnetic resonance spectroscopy ((1)H NMR) were examined. Results demonstrated strong profile separation in old and low aerobic capacity rats, whereas young and high aerobic capacity rat models were less predictive. Significantly differential metabolites between the groups include taurine, acetone, valine, and trimethylamine-N-oxide among other metabolites, specifically citrate, succinate, isovalerate, and proline, were differentially increased in older HCR animals compared with their younger counterparts. When interactions between age and aerobic capacity were examined, results demonstrated that enhanced aerobic capacity could mitigate some but not all age-associated alterations in the metabolomic profile.

  16. Degradation of municipal solid waste in simulated landfill bioreactors under aerobic conditions.

    PubMed

    Slezak, Radoslaw; Krzystek, Liliana; Ledakowicz, Stanislaw

    2015-09-01

    In this study the municipal solid waste degradation processes in simulated landfill bioreactors under aerobic and anaerobic conditions is investigated. The effect of waste aeration on the dynamics of the aerobic degradation processes in lysimeters as well as during anaerobic processes after completion of aeration is presented. The results are compared with the anaerobic degradation process to determine the stabilization stage of waste in both experimental modes. The experiments in aerobic lysimeters were carried out at small aeration rate (4.41⋅10(-3)lmin(-1)kg(-1)) and for two recirculation rates (24.9 and 1.58lm(-3)d(-1)). The change of leachate and formed gases composition showed that the application of even a small aeration rate favored the degradation of organic matter. The amount of CO2 and CH4 released from anaerobic lysimeter was about 5 times lower than that from the aerobic lysimeters. Better stabilization of the waste was obtained in the aerobic lysimeter with small recirculation, from which the amount of CO2 produced was larger by about 19% in comparison with that from the aerobic lysimeter with large leachate recirculation.

  17. Nonterrestrial material processing and manufacturing of large space systems

    NASA Technical Reports Server (NTRS)

    Von Tiesenhausen, G.

    1979-01-01

    Nonterrestrial processing of materials and manufacturing of large space system components from preprocessed lunar materials at a manufacturing site in space is described. Lunar materials mined and preprocessed at the lunar resource complex will be flown to the space manufacturing facility (SMF), where together with supplementary terrestrial materials, they will be final processed and fabricated into space communication systems, solar cell blankets, radio frequency generators, and electrical equipment. Satellite Power System (SPS) material requirements and lunar material availability and utilization are detailed, and the SMF processing, refining, fabricating facilities, material flow and manpower requirements are described.

  18. Large Composite Structures Processing Technologies for Reusable Launch Vehicles

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.; Vickers, J. H.; McMahon, W. M.; Hulcher, A. B.; Johnston, N. J.; Cano, R. J.; Belvin, H. L.; McIver, K.; Franklin, W.; Sidwell, D.

    2001-01-01

    Significant efforts have been devoted to establishing the technology foundation to enable the progression to large scale composite structures fabrication. We are not capable today of fabricating many of the composite structures envisioned for the second generation reusable launch vehicle (RLV). Conventional 'aerospace' manufacturing and processing methodologies (fiber placement, autoclave, tooling) will require substantial investment and lead time to scale-up. Out-of-autoclave process techniques will require aggressive efforts to mature the selected technologies and to scale up. Focused composite processing technology development and demonstration programs utilizing the building block approach are required to enable envisioned second generation RLV large composite structures applications. Government/industry partnerships have demonstrated success in this area and represent best combination of skills and capabilities to achieve this goal.

  19. Microbial community structure in a thermophilic aerobic digester used as a sludge pretreatment process for the mesophilic anaerobic digestion and the enhancement of methane production.

    PubMed

    Jang, Hyun Min; Park, Sang Kyu; Ha, Jeong Hyub; Park, Jong Moon

    2013-10-01

    An effective two-stage sewage sludge digestion process, consisting of thermophilic aerobic digestion (TAD) followed by mesophilic anaerobic digestion (MAD), was developed for efficient sludge reduction and methane production. Using TAD as a biological pretreatment, the total volatile suspended solid reduction (VSSR) and methane production rate (MPR) in the MAD reactor were significantly improved. According to denaturing gradient gel electrophoresis (DGGE) analysis, the results indicated that the dominant bacteria species such as Ureibacillus thermophiles and Bacterium thermus in TAD were major routes for enhancing soluble organic matter. TAD pretreatment using a relatively short SRT of 1 day showed highly increased soluble organic products and positively affected an increment of bacteria populations which performed interrelated microbial metabolisms with methanogenic species in the MAD; consequently, a quantitative real-time PCR indicated greatly increased Methanosarcinales (acetate-utilizing methanogens) in the MAD, resulting in enhanced methane production.

  20. Data Pre-Processing Method to Remove Interference of Gas Bubbles and Cell Clusters During Anaerobic and Aerobic Yeast Fermentations in a Stirred Tank Bioreactor

    NASA Astrophysics Data System (ADS)

    Princz, S.; Wenzel, U.; Miller, R.; Hessling, M.

    2014-11-01

    One aerobic and four anaerobic batch fermentations of the yeast Saccharomyces cerevisiae were conducted in a stirred bioreactor and monitored inline by NIR spectroscopy and a transflectance dip probe. From the acquired NIR spectra, chemometric partial least squares regression (PLSR) models for predicting biomass, glucose and ethanol were constructed. The spectra were directly measured in the fermentation broth and successfully inspected for adulteration using our novel data pre-processing method. These adulterations manifested as strong fluctuations in the shape and offset of the absorption spectra. They resulted from cells, cell clusters, or gas bubbles intercepting the optical path of the dip probe. In the proposed data pre-processing method, adulterated signals are removed by passing the time-scanned non-averaged spectra through two filter algorithms with a 5% quantile cutoff. The filtered spectra containing meaningful data are then averaged. A second step checks whether the whole time scan is analyzable. If true, the average is calculated and used to prepare the PLSR models. This new method distinctly improved the prediction results. To dissociate possible correlations between analyte concentrations, such as glucose and ethanol, the feeding analytes were alternately supplied at different concentrations (spiking) at the end of the four anaerobic fermentations. This procedure yielded low-error (anaerobic) PLSR models for predicting analyte concentrations of 0.31 g/l for biomass, 3.41 g/l for glucose, and 2.17 g/l for ethanol. The maximum concentrations were 14 g/l biomass, 167 g/l glucose, and 80 g/l ethanol. Data from the aerobic fermentation, carried out under high agitation and high aeration, were incorporated to realize combined PLSR models, which have not been previously reported to our knowledge.

  1. Large-scale synthesis of ultrathin tungsten oxide nanowire networks: an efficient catalyst for aerobic oxidation of toluene to benzaldehyde under visible light

    NASA Astrophysics Data System (ADS)

    Bai, Hua; Yi, Wencai; Liu, Jingyao; Lv, Qing; Zhang, Qing; Ma, Qiang; Yang, Haifeng; Xi, Guangcheng

    2016-07-01

    As a very important chemical raw material, the selective formation of benzaldehyde from toluene at preparative or industrial levels requires the use of highly corrosive chlorine and high reaction temperatures, which severely corrodes equipment, pollutes the environment, and consumes a lot of energy. Herein, we report a robust and highly active catalyst for the benzaldehyde evolution reaction that is constructed by the surfactant-free growth of oxygen vacancy-rich W18O49 ultrathin nanowire networks. Under atmospheric pressure and visible-light irradiation, the new catalyst can selectively (92% selectivity) catalyze the aerobic oxidation of toluene to benzaldehyde with yields of above 95%.As a very important chemical raw material, the selective formation of benzaldehyde from toluene at preparative or industrial levels requires the use of highly corrosive chlorine and high reaction temperatures, which severely corrodes equipment, pollutes the environment, and consumes a lot of energy. Herein, we report a robust and highly active catalyst for the benzaldehyde evolution reaction that is constructed by the surfactant-free growth of oxygen vacancy-rich W18O49 ultrathin nanowire networks. Under atmospheric pressure and visible-light irradiation, the new catalyst can selectively (92% selectivity) catalyze the aerobic oxidation of toluene to benzaldehyde with yields of above 95%. Electronic supplementary information (ESI) available: Experimental procedure, XRD patterns, TEM and HRTEM images, energy-dispersive X-ray spectra, UV-vis spectra, X-ray photoelectron spectroscopy (XPS), and EDS. See DOI: 10.1039/c6nr02949c

  2. geoknife: Reproducible web-processing of large gridded datasets

    USGS Publications Warehouse

    Read, Jordan S.; Walker, Jordan I.; Appling, Alison P.; Blodgett, David L.; Read, Emily K.; Winslow, Luke A.

    2016-01-01

    Geoprocessing of large gridded data according to overlap with irregular landscape features is common to many large-scale ecological analyses. The geoknife R package was created to facilitate reproducible analyses of gridded datasets found on the U.S. Geological Survey Geo Data Portal web application or elsewhere, using a web-enabled workflow that eliminates the need to download and store large datasets that are reliably hosted on the Internet. The package provides access to several data subset and summarization algorithms that are available on remote web processing servers. Outputs from geoknife include spatial and temporal data subsets, spatially-averaged time series values filtered by user-specified areas of interest, and categorical coverage fractions for various land-use types.

  3. Distributed Processing of Projections of Large Datasets: A Preliminary Study

    USGS Publications Warehouse

    Maddox, Brian G.

    2004-01-01

    Modern information needs have resulted in very large amounts of data being used in geographic information systems. Problems arise when trying to project these data in a reasonable amount of time and accuracy, however. Current single-threaded methods can suffer from two problems: fast projection with poor accuracy, or accurate projection with long processing time. A possible solution may be to combine accurate interpolation methods and distributed processing algorithms to quickly and accurately convert digital geospatial data between coordinate systems. Modern technology has made it possible to construct systems, such as Beowulf clusters, for a low cost and provide access to supercomputer-class technology. Combining these techniques may result in the ability to use large amounts of geographic data in time-critical situations.

  4. Large-Area Laser-Lift-Off Processing in Microelectronics

    NASA Astrophysics Data System (ADS)

    Delmdahl, R.; Pätzel, R.; Brune, J.

    Laser lift-off is an enabling technology for microelectronics growth markets such as light emitting diodes, densely packaged semiconductor devices, and flexible displays. For example, thin film transistor structures fabricated on top of polymer layers spun on glass carriers must be delaminated from rigid substrates to create lightweight and rugged flexible displays on polymers. Low-thermal-budget processes are generically required to protect adjacent functional films. Excimer lasers provide short UV wavelength and short pulse duration required for highly-localized energy coupling. The high output power of excimer lasers enables a large processing footprint and the high-throughput rates needed in mass manufacturing.

  5. Large Deviation Functional of the Weakly Asymmetric Exclusion Process

    NASA Astrophysics Data System (ADS)

    Enaud, C.; Derrida, B.

    2004-02-01

    We obtain the large deviation functional of a density profile for the asymmetric exclusion process of L sites with open boundary conditions when the asymmetry scales like 1/L. We recover as limiting cases the expressions derived recently for the symmetric (SSEP) and the asymmetric (ASEP) cases. In the ASEP limit, the non linear differential equation one needs to solve can be analysed by a method which resembles the WKB method.

  6. Quantitative prediction of reduction in large pipe setting round process

    NASA Astrophysics Data System (ADS)

    Zhao, Jun; Zhan, Peipei; Ma, Rui; Zhai, Ruixue

    2013-07-01

    The control manner during the process to ensure the quality of pipe products mainly relies on the operator's experience, so it is very necessary to study the setting round process and obtain its spring-back law. The setting round process is shaping an oval section pipe into circular section, so it is difficult to provide a quantificational analysis for its spring-back process because of the curvature inequality of pipe section neutral layer. However, the spring-back law of the circle-oval process can be easily predicted. The experimental method is firstly used to establish the equivalent effect between the setting round process and the circle-oval process. The setting round process can be converted into the circle-oval process. There are two difficulties in the theoretical analysis for the circle-oval process: elastic-plastic bending problem of curved beam; statically indeterminate problem. A quantitative analytic method for the circle-oval process is presented on the basis of combination of the spring-back law of plane curved beam with the element dividing idea in finite element method. The ovality after unloading versus the relative reduction is plotted with analytical and experimental results respectively, which shows a fair agreement. Finally, the method of quantitative prediction of reduction for large pipe setting round is given based on the equivalent effect and the analytical results. Five pipes, which are needed to be set round, are used to carry out experiment so as to verify this method. The results of verification experiment indicates that, in the experimental range, the residual ovality are all under 0.35% after the once only setting round with the theoretical prediction reductions. It is much less than the 1% requirement of pipe standard. Applying the established theoretical analysis is able to correct the pipe ovality with sufficient accuracy, which provides theoretical direction to plant use.

  7. Exposing earth surface process model simulations to a large audience

    NASA Astrophysics Data System (ADS)

    Overeem, I.; Kettner, A. J.; Borkowski, L.; Russell, E. L.; Peddicord, H.

    2015-12-01

    The Community Surface Dynamics Modeling System (CSDMS) represents a diverse group of >1300 scientists who develop and apply numerical models to better understand the Earth's surface. CSDMS has a mandate to make the public more aware of model capabilities and therefore started sharing state-of-the-art surface process modeling results with large audiences. One platform to reach audiences outside the science community is through museum displays on 'Science on a Sphere' (SOS). Developed by NOAA, SOS is a giant globe, linked with computers and multiple projectors and can display data and animations on a sphere. CSDMS has developed and contributed model simulation datasets for the SOS system since 2014, including hydrological processes, coastal processes, and human interactions with the environment. Model simulations of a hydrological and sediment transport model (WBM-SED) illustrate global river discharge patterns. WAVEWATCH III simulations have been specifically processed to show the impacts of hurricanes on ocean waves, with focus on hurricane Katrina and super storm Sandy. A large world dataset of dams built over the last two centuries gives an impression of the profound influence of humans on water management. Given the exposure of SOS, CSDMS aims to contribute at least 2 model datasets a year, and will soon provide displays of global river sediment fluxes and changes of the sea ice free season along the Arctic coast. Over 100 facilities worldwide show these numerical model displays to an estimated 33 million people every year. Datasets storyboards, and teacher follow-up materials associated with the simulations, are developed to address common core science K-12 standards. CSDMS dataset documentation aims to make people aware of the fact that they look at numerical model results, that underlying models have inherent assumptions and simplifications, and that limitations are known. CSDMS contributions aim to familiarize large audiences with the use of numerical

  8. Mechanical model of precursory source processes for some large earthquakes

    SciTech Connect

    Dmorvska, R.; Li, V.C.

    1982-04-01

    A mechanical model is presented of precursory source processes for some large earthquakes along plate boundaries. It is assumed that the pre-seismic period consists of the upward progression of a zone of slip from lower portions of the lithosphere towards the Earth's surface. The slip front is blocked by local asperities of different size and strength; these asperities may be zones of real alteration of inherent strength, or instead may be zones which are currently stronger due to a local slowdown of a basically rate-dependent frictional response. Such blocking by a single, large asperity, or array of asperities, produces quiescence over a segment of plate boundary, until gradual increase of the stress concentration forces the slip zone through the blocked region at one end of the gap, thus nucleating a seismic rupture that propogates upwards and towards the other end. This model is proposed to explain certain distinctive seismicity patterns that have been observed before large earthquakes, notably quiescence over the gap zone followed by clustering at its end prior to the main event. A discussion of mechanical factors influencing the process is presented and some introductory modelling, performed with the use of a generalized Elsasser model for lithospheric plates and the ''line spring'' model for part-through flaws (slip zones) at plate boundaries, is outlined briefly.

  9. Large Coaxial Coldfinger Ptc for Process Liquefaction and Hts Applications

    NASA Astrophysics Data System (ADS)

    Spoor, P. S.; Corey, J. A.

    2010-04-01

    Large (>100 W cooling capacity at 80 K) `pulse-tube' coolers are ideal candidates for emerging applications such as HTS transmission lines, transformers, and motor windings, meso-scale oxygen liquefaction on-demand, cryopumping, and cryogen boiloff recovery. A number of successful large `in-line' pulse-tube coolers have been built, but these require embedded shell-and-tube process heat exchangers, hence transport of the process fluid/gas to and from the coldhead, and often a high degree of process fluid purity, to avoid clogging in the narrow inlets and outlets of these heat exchangers. It is far preferable in most circumstances to have a coldfinger design that presents a salient cold tip, with the coldhead at the end of a flexible transfer line, as is done with Gifford-McMahon or Joule-Thomson coolers. This paper presents some design details and data from the development of our first high-capacity coldfinger, as well as the results of its application to a 55 gallon/day oxygen liquefier for the Navy.

  10. Large Eddy Simulation of Cryogenic Injection Processes at Supercritical Pressure

    NASA Technical Reports Server (NTRS)

    Oefelein, Joseph C.; Garcia, Roberto (Technical Monitor)

    2002-01-01

    This paper highlights results from the first of a series of hierarchical simulations aimed at assessing the modeling requirements for application of the large eddy simulation technique to cryogenic injection and combustion processes in liquid rocket engines. The focus is on liquid-oxygen-hydrogen coaxial injectors at a condition where the liquid-oxygen is injected at a subcritical temperature into a supercritical environment. For this situation a diffusion dominated mode of combustion occurs in the presence of exceedingly large thermophysical property gradients. Though continuous, these gradients approach the behavior of a contact discontinuity. Significant real gas effects and transport anomalies coexist locally in colder regions of the flow, with ideal gas and transport characteristics occurring within the flame zone. The current focal point is on the interfacial region between the liquid-oxygen core and the coaxial hydrogen jet where the flame anchors itself.

  11. Exact Large Deviation Function in the Asymmetric Exclusion Process

    NASA Astrophysics Data System (ADS)

    Derrida, Bernard; Lebowitz, Joel L.

    1998-01-01

    By an extension of the Bethe ansatz method used by Gwa and Spohn, we obtain an exact expression for the large deviation function of the time averaged current for the fully asymmetric exclusion process in a ring containing N sites and p particles. Using this expression we easily recover the exact diffusion constant obtained earlier and calculate as well some higher cumulants. The distribution of the deviation y of the average current is, in the limit N-->∞, skew and decays like exp-\\(Ay5/2\\) for y-->+∞ and exp-\\(A'\\|y\\|3/2\\) for y-->-∞. Surprisingly, the large deviation function has an expression very similar to the pressure (as a function of the density) of an ideal Bose or Fermi gas in 3D.

  12. Fast methods for training Gaussian processes on large datasets

    PubMed Central

    Moore, C. J.; Berry, C. P. L.; Gair, J. R.

    2016-01-01

    Gaussian process regression (GPR) is a non-parametric Bayesian technique for interpolating or fitting data. The main barrier to further uptake of this powerful tool rests in the computational costs associated with the matrices which arise when dealing with large datasets. Here, we derive some simple results which we have found useful for speeding up the learning stage in the GPR algorithm, and especially for performing Bayesian model comparison between different covariance functions. We apply our techniques to both synthetic and real data and quantify the speed-up relative to using nested sampling to numerically evaluate model evidences. PMID:27293793

  13. Aerobic microbial enhanced oil recovery

    SciTech Connect

    Torsvik, T.; Gilje, E.; Sunde, E.

    1995-12-31

    In aerobic MEOR, the ability of oil-degrading bacteria to mobilize oil is used to increase oil recovery. In this process, oxygen and mineral nutrients are injected into the oil reservoir in order to stimulate growth of aerobic oil-degrading bacteria in the reservoir. Experiments carried out in a model sandstone with stock tank oil and bacteria isolated from offshore wells showed that residual oil saturation was lowered from 27% to 3%. The process was time dependent, not pore volume dependent. During MEOR flooding, the relative permeability of water was lowered. Oxygen and active bacteria were needed for the process to take place. Maximum efficiency was reached at low oxygen concentrations, approximately 1 mg O{sub 2}/liter.

  14. The effect of recycling flux on the performance and microbial community composition of a biofilm hydrolytic-aerobic recycling process treating anthraquinone reactive dyes.

    PubMed

    Wang, Yuanpeng; Zhu, Kang; Zheng, Yanmei; Wang, Haitao; Dong, Guowen; He, Ning; Li, Qingbiao

    2011-11-25

    Synthetic dyes are extensively used and rarely degraded. Microbial decomposition is a cost-effective alternative to chemical and physical degradation processes. In this study, the decomposition of simulated anthraquinone reactive dye (Reactive Blue 19; RB19) at a concentration of 400-mg/L in wastewater by a biofilm hydrolytic-aerobic recycling system was investigated over a range of recycling fluxes. The 16S rDNA-based fingerprint technique was also used to investigate the microbial community composition. Results indicated that the recycling flux was a key factor that influenced RB19 degradation. The RB19 and COD removal efficiency could reach values as high as 82.1% and 95.4%, respectively, with a recycling flux of 10 mL/min. Molecular analysis indicated that some strains were similar to Aeromonadales, Tolumonas, and some uncultured clones were assumed to be potential decolorization bacteria. However, the microbial community composition in the reactors remained relatively stable at different recycling fluxes. This study provided insights on the decolorization capability and the population dynamics during the decolorization process of anthraquinone dye wastewater.

  15. Effects of rapid temperature rising on nitrogen removal and microbial community variation of anoxic/aerobic process for ABS resin wastewater treatment.

    PubMed

    Luo, Huilong; Song, Yudong; Zhou, Yuexi; Yang, Liwei; Zhao, Yaqian

    2017-02-01

    ABS resin wastewater is a high-temperature nitrogenous organic wastewater. It can be successfully treated with anoxic/aerobic (A/O) process. In this study, the effect of temperature on nitrogen removal and microbial community after quick temperature rise (QTR) was investigated. It was indicated that QTR from 25 to 30 °C facilitated the microbial growth and achieved a similar effluent quality as that at 25 °C. QTR from 25 to 35 °C or 40 °C resulted in higher effluent concentration of chemical oxygen demand (COD), biochemical oxygen demand (BOD5), total nitrogen (TN), and total phosphorus (TP). Illumina MiSeq pyrosequencing analysis illustrated that the richness and diversity of the bacterial community was decreased as the temperature was increased. The percentage of many functional groups was changed significantly. QTR from 25 to 40 °C also resulted in the inhibition of ammonia oxidation rate and high concentration of free ammonia, which then inhibited the growth of NOB (Nitrospira), and thus resulted in nitrite accumulation. The high temperature above 35 °C promoted the growth of a denitrifying bacterial genus, Denitratisoma, which might increase N2O production during the denitrification process.

  16. Aerobic treatment of wine-distillery wastewaters

    SciTech Connect

    Sales, D.; Valcarcel, M.J.; Perez, L.; de la Ossa, E.M.

    1987-01-01

    Waste from food-processing and allied industries is largely made up of organic compounds which can be metabolized by aerobic or anaerobic means. However, these wastes present a series of problems to biological depuration plants, such as the need for prior treatment to establish conditions suitable for the development of the microorganisms responsible for the process; and the long retention time of the biomass if acceptable effluents are to be obtained. Again, the seasonal nature of many of these industries makes for very heterogeneous waste. This means that treatment plant must be versatile and are subject to rapid successions of close-down and start-up interspersed with long intervals of inactivity. All these difficulties oblige the industries in the sector to adapt depurative technology to their particular needs. Wine distilleries fall into this general category. Their waste (called vinasses) is acidic, has a high organic content and varies widely according to the raw matter distilled: wine, lies, etc. This paper studies the start-up of digestors for aerobic treatment of vinasses and the establishment of optimum operating conditions for an adequate depurative performance.

  17. Enabling materials and processes for large aerospace mirrors

    NASA Astrophysics Data System (ADS)

    Matson, Lawrence E.; Chen, Ming Y.

    2008-07-01

    The use of monolithic glass to produce large, rigid segmented members for lightweight space-based mirror systems appears to have reached its limits due to the long production lead times, high processing costs, and launch load/weight requirements. New material solutions and processes are required to meet the US Air Force's optical needs for directed energy, reconnaissance/surveillance, and communications. Mirror structural substrates made out of advanced materials (metal, ceramic, and polymer), composites, foams, and microsphere arrays should allow for CTE and modulus tailorability, low-density, and high values in strength, stiffness, thermal conductivity and toughness. Conventional mechanical polishing to visual specifications for figure and surface finish roughness requirements will be difficult, due to the multi-phase complexities of these new systems. Advances in surface removal technologies as well as replication processes will be required to produce the required optical finishes with reduced schedule and cost. In this paper selected material and process solutions being considered will be discussed.

  18. Ultrasonic processing of dairy systems in large scale reactors.

    PubMed

    Zisu, Bogdan; Bhaskaracharya, Raman; Kentish, Sandra; Ashokkumar, Muthupandian

    2010-08-01

    High intensity low frequency ultrasound was used to process dairy ingredients to improve functional properties. Based on a number of lab-scale experiments, several experimental parameters were optimised for processing large volumes of whey and casein-based dairy systems in pilot scale ultrasonic reactors. A continuous sonication process at 20 kHz capable of delivering up to 4 kW of power with a flow-through reactor design was used to treat dairy ingredients at flow rates ranging from 200 to 6000 mL/min. Dairy ingredients treated by ultrasound included reconstituted whey protein concentrate (WPC), whey protein and milk protein retentates and calcium caseinate. The sonication of solutions with a contact time of less than 1 min and up to 2.4 min led to a significant reduction in the viscosity of materials containing 18% to 54% (w/w) solids. The viscosity of aqueous dairy ingredients treated with ultrasound was reduced by between 6% and 50% depending greatly on the composition, processing history, acoustic power and contact time. A notable improvement in the gel strength of sonicated and heat coagulated dairy systems was also observed. When sonication was combined with a pre-heat treatment of 80 degrees C for 1 min or 85 degrees C for 30s, the heat stability of the dairy ingredients containing whey proteins was significantly improved. The effect of sonication was attributed mainly to physical forces generated through acoustic cavitation as supported by particle size reduction in response to sonication. As a result, the gelling properties and heat stability aspects of sonicated dairy ingredients were maintained after spray drying and reconstitution. Overall, the sonication procedure for processing dairy systems may be used to improve process efficiency, improve throughput and develop value added ingredients with the potential to deliver economical benefits to the dairy industry.

  19. Processing Ocean Images to Detect Large Drift Nets

    NASA Technical Reports Server (NTRS)

    Veenstra, Tim

    2009-01-01

    A computer program processes the digitized outputs of a set of downward-looking video cameras aboard an aircraft flying over the ocean. The purpose served by this software is to facilitate the detection of large drift nets that have been lost, abandoned, or jettisoned. The development of this software and of the associated imaging hardware is part of a larger effort to develop means of detecting and removing large drift nets before they cause further environmental damage to the ocean and to shores on which they sometimes impinge. The software is capable of near-realtime processing of as many as three video feeds at a rate of 30 frames per second. After a user sets the parameters of an adjustable algorithm, the software analyzes each video stream, detects any anomaly, issues a command to point a high-resolution camera toward the location of the anomaly, and, once the camera has been so aimed, issues a command to trigger the camera shutter. The resulting high-resolution image is digitized, and the resulting data are automatically uploaded to the operator s computer for analysis.

  20. UAV Data Processing for Large Scale Topographical Mapping

    NASA Astrophysics Data System (ADS)

    Tampubolon, W.; Reinhardt, W.

    2014-06-01

    Large scale topographical mapping in the third world countries is really a prominent challenge in geospatial industries nowadays. On one side the demand is significantly increasing while on the other hand it is constrained by limited budgets available for mapping projects. Since the advent of Act Nr.4/yr.2011 about Geospatial Information in Indonesia, large scale topographical mapping has been on high priority for supporting the nationwide development e.g. detail spatial planning. Usually large scale topographical mapping relies on conventional aerial survey campaigns in order to provide high resolution 3D geospatial data sources. Widely growing on a leisure hobby, aero models in form of the so-called Unmanned Aerial Vehicle (UAV) bring up alternative semi photogrammetric aerial data acquisition possibilities suitable for relatively small Area of Interest (AOI) i.e. <5,000 hectares. For detail spatial planning purposes in Indonesia this area size can be used as a mapping unit since it usually concentrates on the basis of sub district area (kecamatan) level. In this paper different camera and processing software systems will be further analyzed for identifying the best optimum UAV data acquisition campaign components in combination with the data processing scheme. The selected AOI is covering the cultural heritage of Borobudur Temple as one of the Seven Wonders of the World. A detailed accuracy assessment will be concentrated within the object feature of the temple at the first place. Feature compilation involving planimetric objects (2D) and digital terrain models (3D) will be integrated in order to provide Digital Elevation Models (DEM) as the main interest of the topographic mapping activity. By doing this research, incorporating the optimum amount of GCPs in the UAV photo data processing will increase the accuracy along with its high resolution in 5 cm Ground Sampling Distance (GSD). Finally this result will be used as the benchmark for alternative geospatial

  1. High-Pressure Hydrothermal Processing in Large Icy Satellites

    NASA Astrophysics Data System (ADS)

    Scott, H. P.; Hemley, R. J.; Ryerson, F. J.; Williams, Q.

    2002-12-01

    We have conducted a series of experiments designed to simulate chemical processes within large icy satellites. Few phase equilibria data exist which are relevant to the chemical evolution of moons such as Jupiter's Europa and Ganymede, Saturn's Titan and Neptune's Triton; however, models of their interiors are critically dependent on their internal chemistry and density. An internally generated magnetic field has been observed for Ganymede which implies the existence of a liquid metallic core, and accordingly an interior temperature exceeding 1000ṡC. This observation, coupled with the known abundance of water ice on Ganymede, suggests that rock - water interactions at high temperatures and pressures (prospectively in the past) would control the interior mineralogy of these satellites. Additionally, organic material has been observed on the surface of Ganymede, and in conjunction with the large complement of water ice, it has been suggested that icy satellites possess the prerequisites for life to originate; however, the stability of organic material under high-pressure hydrothermal processing is unclear. We used a piston-cylinder press to react material of carbonaceous chondrite chemistry with H2O at a range of temperatures and oxidation states at a pressure of 1.5 GPa, and make the following observations: 1) At temperatures below ~850ṡC the density of the rock interior will be largely that of hydrated ferromagnesian silicates (serpentine - chlorite - talc depending on temperature and oxidation state), 2) Iron and sulfur alloy readily under these conditions, forming the mineral pyrrhotite -- a metallic core of this chemistry is therefore likely, and 3) Hydrothermal processing of organic species of carbon at temperatures above 450ṡC produces carbonate minerals -- the prerequisite materials for life are not preserved deep within icy satellites. To further investigate the high-pressure hydrothermal processing of organic material we are conducting experiments

  2. Large earthquake processes in the northern Vanuatu subduction zone

    NASA Astrophysics Data System (ADS)

    Cleveland, K. Michael; Ammon, Charles J.; Lay, Thorne

    2014-12-01

    The northern Vanuatu (formerly New Hebrides) subduction zone (11°S to 14°S) has experienced large shallow thrust earthquakes with Mw > 7 in 1966 (MS 7.9, 7.3), 1980 (Mw 7.5, 7.7), 1997 (Mw 7.7), 2009 (Mw 7.7, 7.8, 7.4), and 2013 (Mw 8.0). We analyze seismic data from the latter four earthquake sequences to quantify the rupture processes of these large earthquakes. The 7 October 2009 earthquakes occurred in close spatial proximity over about 1 h in the same region as the July 1980 doublet. Both sequences activated widespread seismicity along the northern Vanuatu subduction zone. The focal mechanisms indicate interplate thrusting, but there are differences in waveforms that establish that the events are not exact repeats. With an epicenter near the 1980 and 2009 events, the 1997 earthquake appears to have been a shallow intraslab rupture below the megathrust, with strong southward directivity favoring a steeply dipping plane. Some triggered interplate thrusting events occurred as part of this sequence. The 1966 doublet ruptured north of the 1980 and 2009 events and also produced widespread aftershock activity. The 2013 earthquake rupture propagated southward from the northern corner of the trench with shallow slip that generated a substantial tsunami. The repeated occurrence of large earthquake doublets along the northern Vanuatu subduction zone is remarkable considering the doublets likely involved overlapping, yet different combinations of asperities. The frequent occurrence of large doublet events and rapid aftershock expansion in this region indicate the presence of small, irregularly spaced asperities along the plate interface.

  3. Process monitoring during manufacturing of large-scale composite parts

    NASA Astrophysics Data System (ADS)

    Heider, Dirk; Eckel, Douglas A., II; Don, Roderic C.; Fink, Bruce K.; Gillespie, John W., Jr.

    1999-01-01

    One of the inherent problems with the processing of composites is the development of internal stresses and the resulting warpage, which results in out-of-tolerance components. This investigation examines possible fiber-optic sensor methods, which can be applied to measure internal strain and thus residual stress during production. Extrinsic Fabry-Perot Interferometers (EFPI) and Bragg gratings are utilizes to monitor the strain behavior during manufacturing of large-scale composite parts. Initially, a 24 in X 18 in X 1 in thick part was manufactured using the vacuum- assisted resin transfer molding (VARTM) technique. In this part, one Bragg grating, multiple thermocouples and a resin flow sensor (SMARTweave) were integrate to measure the flow and cure behavior during production. An AGEMA thermal image camera verified the temperature history on the part surface. In addition, several EFPI's and Bragg gratings were implemented into three temperature history on the part surface. In addition, several EFPI's and Bragg gratings were implemented into three 13 ft X 32 ft X 20.3 in civilian bridge deck test specimens manufactured with the VARTM process. The Bragg gratings showed great promise to capture the changes in strain due to the residual stress during cure. The actual implementation of fiber optics into large composite parts is a challenge and the problems of sensor survivability in these parts are addressed in this study. The fiber optic measurements in combination with SMARTweave's ability to monitor flow could lead to a sensor system, which allows feedback for process control of the VARTM technique. In addition, the optical fibers will be used for health monitoring during the lifetime of the part.

  4. High-throughput solution processing of large-scale graphene.

    PubMed

    Tung, Vincent C; Allen, Matthew J; Yang, Yang; Kaner, Richard B

    2009-01-01

    The electronic properties of graphene, such as high charge carrier concentrations and mobilities, make it a promising candidate for next-generation nanoelectronic devices. In particular, electrons and holes can undergo ballistic transport on the sub-micrometre scale in graphene and do not suffer from the scale limitations of current MOSFET technologies. However, it is still difficult to produce single-layer samples of graphene and bulk processing has not yet been achieved, despite strenuous efforts to develop a scalable production method. Here, we report a versatile solution-based process for the large-scale production of single-layer chemically converted graphene over the entire area of a silicon/SiO(2) wafer. By dispersing graphite oxide paper in pure hydrazine we were able to remove oxygen functionalities and restore the planar geometry of the single sheets. The chemically converted graphene sheets that were produced have the largest area reported to date (up to 20 x 40 microm), making them far easier to process. Field-effect devices have been fabricated by conventional photolithography, displaying currents that are three orders of magnitude higher than previously reported for chemically produced graphene. The size of these sheets enables a wide range of characterization techniques, including optical microscopy, scanning electron microscopy and atomic force microscopy, to be performed on the same specimen.

  5. High-throughput solution processing of large-scale graphene

    NASA Astrophysics Data System (ADS)

    Tung, Vincent C.; Allen, Matthew J.; Yang, Yang; Kaner, Richard B.

    2009-01-01

    The electronic properties of graphene, such as high charge carrier concentrations and mobilities, make it a promising candidate for next-generation nanoelectronic devices. In particular, electrons and holes can undergo ballistic transport on the sub-micrometre scale in graphene and do not suffer from the scale limitations of current MOSFET technologies. However, it is still difficult to produce single-layer samples of graphene and bulk processing has not yet been achieved, despite strenuous efforts to develop a scalable production method. Here, we report a versatile solution-based process for the large-scale production of single-layer chemically converted graphene over the entire area of a silicon/SiO2 wafer. By dispersing graphite oxide paper in pure hydrazine we were able to remove oxygen functionalities and restore the planar geometry of the single sheets. The chemically converted graphene sheets that were produced have the largest area reported to date (up to 20 × 40 µm), making them far easier to process. Field-effect devices have been fabricated by conventional photolithography, displaying currents that are three orders of magnitude higher than previously reported for chemically produced graphene. The size of these sheets enables a wide range of characterization techniques, including optical microscopy, scanning electron microscopy and atomic force microscopy, to be performed on the same specimen.

  6. Process control of large-scale finite element simulation software

    SciTech Connect

    Spence, P.A.; Weingarten, L.I.; Schroder, K.; Tung, D.M.; Sheaffer, D.A.

    1996-02-01

    We have developed a methodology for coupling large-scale numerical codes with process control algorithms. Closed-loop simulations were demonstrated using the Sandia-developed finite element thermal code TACO and the commercially available finite element thermal-mechanical code ABAQUS. This new capability enables us to use computational simulations for designing and prototyping advanced process-control systems. By testing control algorithms on simulators before building and testing hardware, enormous time and cost savings can be realized. The need for a closed-loop simulation capability was demonstrated in a detailed design study of a rapid-thermal-processing reactor under development by CVC Products Inc. Using a thermal model of the RTP system as a surrogate for the actual hardware, we were able to generate response data needed for controller design. We then evaluated the performance of both the controller design and the hardware design by using the controller to drive the finite element model. The controlled simulations provided data on wafer temperature uniformity as a function of ramp rate, temperature sensor locations, and controller gain. This information, which is critical to reactor design, cannot be obtained from typical open-loop simulations.

  7. Large-cell Monte Carlo renormalization of irreversible growth processes

    NASA Technical Reports Server (NTRS)

    Nakanishi, H.; Family, F.

    1985-01-01

    Monte Carlo sampling is applied to a recently formulated direct-cell renormalization method for irreversible, disorderly growth processes. Large-cell Monte Carlo renormalization is carried out for various nonequilibrium problems based on the formulation dealing with relative probabilities. Specifically, the method is demonstrated by application to the 'true' self-avoiding walk and the Eden model of growing animals for d = 2, 3, and 4 and to the invasion percolation problem for d = 2 and 3. The results are asymptotically in agreement with expectations; however, unexpected complications arise, suggesting the possibility of crossovers, and in any case, demonstrating the danger of using small cells alone, because of the very slow convergence as the cell size b is extrapolated to infinity. The difficulty of applying the present method to the diffusion-limited-aggregation model, is commented on.

  8. Plasma generating apparatus for large area plasma processing

    DOEpatents

    Tsai, Chin-Chi; Gorbatkin, Steven M.; Berry, Lee A.

    1991-01-01

    A plasma generating apparatus for plasma processing applications is based on a permanent magnet line-cusp plasma confinement chamber coupled to a compact single-coil microwave waveguide launcher. The device creates an electron cyclotron resonance (ECR) plasma in the launcher and a second ECR plasma is created in the line cusps due to a 0.0875 tesla magnetic field in that region. Additional special magnetic field configuring reduces the magnetic field at the substrate to below 0.001 tesla. The resulting plasma source is capable of producing large-area (20-cm diam), highly uniform (.+-.5%) ion beams with current densities above 5 mA/cm.sup.2. The source has been used to etch photoresist on 5-inch diam silicon wafers with good uniformity.

  9. Plasma generating apparatus for large area plasma processing

    DOEpatents

    Tsai, C.C.; Gorbatkin, S.M.; Berry, L.A.

    1991-07-16

    A plasma generating apparatus for plasma processing applications is based on a permanent magnet line-cusp plasma confinement chamber coupled to a compact single-coil microwave waveguide launcher. The device creates an electron cyclotron resonance (ECR) plasma in the launcher and a second ECR plasma is created in the line cusps due to a 0.0875 tesla magnetic field in that region. Additional special magnetic field configuring reduces the magnetic field at the substrate to below 0.001 tesla. The resulting plasma source is capable of producing large-area (20-cm diam), highly uniform (.+-.5%) ion beams with current densities above 5 mA/cm[sup 2]. The source has been used to etch photoresist on 5-inch diam silicon wafers with good uniformity. 3 figures.

  10. Development of Safe and Scalable Continuous-Flow Methods for Palladium-Catalyzed Aerobic Oxidation Reactions†

    PubMed Central

    Ye, Xuan; Diao, Tianning

    2010-01-01

    Summary The synthetic scope and utility of Pd-catalyzed aerobic oxidation reactions has advanced significantly over the past decade, and these reactions have potential to address important green-chemistry challenges in the pharmaceutical industry. This potential has been unrealized, however, because safety concerns and process constraints hinder large-scale applications of this chemistry. These limitations are addressed by the development of a continuous-flow tube reactor, which has been demonstrated on several scales in the aerobic oxidation of alcohols. Use of a dilute oxygen gas source (8% O2 in N2) ensures that the oxygen/organic mixture never enters the explosive regime, and efficient gas-liquid mixing in the reactor minimizes decomposition of the homogeneous catalyst into inactive Pd metal. These results provide the basis for large-scale implementation of palladium-catalyzed (and other) aerobic oxidation reactions for pharmaceutical synthesis. PMID:20694169

  11. Simultaneous C and N removal from saline salmon effluents in filter reactors comprising anoxic-anaerobic-aerobic processes: effect of recycle ratio.

    PubMed

    Giustinianovich, Elisa A; Aspé, Estrella R; Huiliñir, César E; Roeckel, Marlene D

    2014-01-01

    Salmon processing generates saline effluents with high protein load. To treat these effluents, three compact tubular filter reactors were installed and an integrated anoxic/anaerobic/aerobic process was developed with recycling flow from the reactor's exit to the inlet stream in order to save organic matter (OM) for denitrification. The reactors were aerated in the upper section with recycle ratios (RR) of 0, 2, and 10, respectively, at 30°C. A tubular reactor behave as a plug flow reactor when RR = 0, and as a mixed flow reactor when recycle increases, thus, different RR values were used to evaluate how it affects the product distribution and the global performance. Diluted salmon process effluent was prepared as substrate. Using loads of 1.0 kg COD m(-3)d(-1) and 0.15 kg total Kjeldahl nitrogen (TKN) m(-3)d(-1) at HRT of 2 d, 100% removal efficiencies for nitrite and nitrate were achieved in the anoxic-denitrifying section without effect of the dissolved oxygen in the recycled flow on denitrification. Removals >98% for total organic carbon (TOC) was achieved in the three reactors. The RR had no effect on the TOC removal; nevertheless a higher efficiency in total nitrogen removal in the reactor with the highest recycle ratio was observed: 94.3% for RR = 10 and 46.6% for RR = 2. Results showed that the proposed layout with an alternative distribution in a compact reactor can efficiently treat high organic carbon and nitrogen concentrations from a saline fish effluent with OM savings in denitrification.

  12. Hydrothermal processes above the Yellowstone magma chamber: Large hydrothermal systems and large hydrothermal explosions

    USGS Publications Warehouse

    Morgan, L.A.; Shanks, W.C. Pat; Pierce, K.L.

    2009-01-01

    Hydrothermal explosions are violent and dramatic events resulting in the rapid ejection of boiling water, steam, mud, and rock fragments from source craters that range from a few meters up to more than 2 km in diameter; associated breccia can be emplaced as much as 3 to 4 km from the largest craters. Hydrothermal explosions occur where shallow interconnected reservoirs of steam- and liquid-saturated fluids with temperatures at or near the boiling curve underlie thermal fields. Sudden reduction in confi ning pressure causes fluids to fl ash to steam, resulting in signifi cant expansion, rock fragmentation, and debris ejection. In Yellowstone, hydrothermal explosions are a potentially signifi cant hazard for visitors and facilities and can damage or even destroy thermal features. The breccia deposits and associated craters formed from hydrothermal explosions are mapped as mostly Holocene (the Mary Bay deposit is older) units throughout Yellowstone National Park (YNP) and are spatially related to within the 0.64-Ma Yellowstone caldera and along the active Norris-Mammoth tectonic corridor. In Yellowstone, at least 20 large (>100 m in diameter) hydrothermal explosion craters have been identifi ed; the scale of the individual associated events dwarfs similar features in geothermal areas elsewhere in the world. Large hydrothermal explosions in Yellowstone have occurred over the past 16 ka averaging ??1 every 700 yr; similar events are likely in the future. Our studies of large hydrothermal explosion events indicate: (1) none are directly associated with eruptive volcanic or shallow intrusive events; (2) several historical explosions have been triggered by seismic events; (3) lithic clasts and comingled matrix material that form hydrothermal explosion deposits are extensively altered, indicating that explosions occur in areas subjected to intense hydrothermal processes; (4) many lithic clasts contained in explosion breccia deposits preserve evidence of repeated fracturing

  13. Sustainable multistage process for enhanced productivity of bioplastics from waste remediation through aerobic dynamic feeding strategy: Process integration for up-scaling.

    PubMed

    Amulya, K; Jukuri, Srinivas; Venkata Mohan, S

    2015-01-01

    Polyhydroxyalkanoates (PHA) production was evaluated in a multistage operation using food waste as a renewable feedstock. The first step involved the production of bio-hydrogen (bio-H2) via acidogenic fermentation. Volatile fatty acid (VFA) rich effluent from bio-H2 reactor was subsequently used for PHA production, which was carried out in two stages, Stage II (culture enrichment) and Stage III (PHA production). PHA-storing microorganisms were enriched in a sequencing batch reactor (SBR), operated at two different cycle lengths (CL-24; CL-12). Higher polymer recovery as well as VFA removal was achieved in CL-12 operation both in Stage II (16.3% dry cell weight (DCW); VFA removal, 84%) and Stage III (23.7% DCW; VFA removal, 88%). The PHA obtained was a co-polymer [P(3HB-co-3HV)] of PHB and PHV. The results obtained indicate that this integrated multistage process offers new opportunities to further leverage large scale PHA production with simultaneous waste remediation in the framework of biorefinery.

  14. Reduction of N2O and NO generation in anaerobic-aerobic (low dissolved oxygen) biological wastewater treatment process by using sludge alkaline fermentation liquid.

    PubMed

    Zhu, Xiaoyu; Chen, Yinguang

    2011-03-15

    This paper reported an efficient method to significantly reduce nitrous oxide (N(2)O) and nitric oxide (NO) generation in anaerobic-aerobic (low dissolved oxygen) processes. It was found that by the use of waste-activated sludge alkaline fermentation liquid as the synthetic wastewater-carbon source, compared with the commonly used carbon source in the literature (e.g., acetic acid), the generation of N(2)O and NO was reduced by 68.7% and 50.0%, respectively, but the removal efficiencies of total phosphorus (TP) and total nitrogen (TN) were improved. Both N(2)O and NO were produced in the low dissolved oxygen (DO) stage, and the use of sludge fermentation liquid greatly reduced their generation from the denitrification. The presences of Cu(2+) and propionic acid in fermentation liquid were observed to play an important role in the reduction of N(2)O and NO generation. The analysis of the activities of denitrifying enzymes suggested that sludge fermentation liquid caused the significant decrease of both nitrite reductase activity to NO reductase activity ratio and NO reductase activity to N(2)O reductase activity ratio, which resulted in the lower generation of NO and N(2)O. Fluorescence in situ hybridization analysis indicated that the number of glycogen accumulating bacteria, which was reported to be relevant to nitrous oxide generation, in sludge fermentation liquid reactor was much lower than that in acetic acid reactor. The quantitative detection of the nosZ gene, encoding nitrous oxide reductase, showed that the use of fermentation liquid increased the number of bacteria capable of reducing N(2)O to N(2). The feasibility of using sludge fermentation liquid to reduce NO and N(2)O generation in an anaerobic-low DO process was finally confirmed for a municipal wastewater.

  15. Calcium precipitate induced aerobic granulation.

    PubMed

    Wan, Chunli; Lee, Duu-Jong; Yang, Xue; Wang, Yayi; Wang, Xingzu; Liu, Xiang

    2015-01-01

    Aerobic granulation is a novel biotechnology for wastewater treatment. This study refined existing aerobic granulation mechanisms as a sequencing process including formation of calcium precipitate under alkaline pH to form inorganic cores, followed by bacterial attachment and growth on these cores to form the exopolysaccharide matrix. Mature granules comprised an inner core and a matrix layer and a rim layer with enriched microbial strains. The inorganic core was a mix of different crystals of calcium and phosphates. Functional strains including Sphingomonas sp., Paracoccus sp. Sinorhizobium americanum strain and Flavobacterium sp. attached onto the cores. These functional strains promote c-di-GMP production and the expression by Psl and Alg genes for exopolysaccharide production to enhance formation of mature granules.

  16. Depositional processes in large-scale debris-flow experiments

    USGS Publications Warehouse

    Major, J.J.

    1997-01-01

    This study examines the depositional process and characteristics of deposits of large-scale experimental debris flows (to 15 m3) composed of mixtures of gravel (to 32 mm), sand, and mud. The experiments were performed using a 95-m-long, 2-m-wide debris-flow flume that slopes 31??. Following release, experimental debris flows invariably developed numerous shallow (???10 cm deep) surges. Sediment transported by surges accumulated abruptly on a 3?? runout slope at the mouth of the flume. Deposits developed in a complex manner through a combination of shoving forward and shouldering aside previously deposited debris and through progressive vertical accretion. Progressive accretion by the experimental flows is contrary to commonly assumed en masse sedimentation by debris flows. Despite progressive sediment emplacement, deposits were composed of unstratified accumulations of generally unsorted debris; hence massively textured, poorly sorted debris-flow deposits are not emplaced uniquely en masse. The depositional process was recorded mainly by deposit morphology and surface texture and was not faithfully registered by interior sedimentary texture; homogeneous internal textures could be misinterpreted as the result of en masse emplacement by a single surge. Deposition of sediment by similar, yet separate, debris flows produced a homogenous, massively textured composite deposit having little stratigraphic distinction. Similar deposit characteristics and textures are observed in natural debris-flow deposits. Experimental production of massively textured deposits by progressive sediment accretion limits interpretations that can be drawn from deposit characteristics and casts doubt on methods of estimating flow properties from deposit thickness or from relations between particle size and bed thickness.

  17. Aerobic granulation of aggregating consortium X9 isolated from aerobic granules and role of cyclic di-GMP.

    PubMed

    Wan, Chunli; Yang, Xue; Lee, Duu-Jong; Wang, Xin-Yue; Yang, Qiaoli; Pan, Xiangliang

    2014-01-01

    This study monitored the granulation process of an aggregating functional consortium X9 that was consisted of Pseudomonas putida X-1, Acinetobacter sp. X-2, Alcaligenes sp. X-3 and Comamonas testosteroni X-4 in shaken reactors. The growth curve of X9 was fit using logistic model as follows y=1.49/(1+21.3*exp(-0.33x)), the maximum specific cell growth rate for X9 was 0.33 h(-1). Initially X9 consumed polysaccharides (PS) and secreted proteins (PN) to trigger granulation. Then X9 grew in biomass and formed numerous micro-granules, driven by increasing hydrophobicity of cell membranes and of accumulated extracellular polymeric substances (EPS). In later stage the intracellular cyclic diguanylate (c-di-GMP) was at high levels for inhibiting bacteria swarming motility, thereby promotion formation of large aerobic granules. The findings reported herein advise the way to accelerate granule formation and to stabilize operation in aerobic granular reactors.

  18. What Is Aerobic Dancing?

    MedlinePlus

    ... aerobics can reach up to six times the force of gravity, which is transmitted to each of the 26 bones in the foot. Because of the many side-to-side motions, shoes need an arch design that will compensate ...

  19. A process yields large quantities of pure ribosome subunits

    NASA Technical Reports Server (NTRS)

    Friedman, M.; Lu, P.; Rich, A.

    1972-01-01

    Development of process for in-vitro protein synthesis from living cells followed by dissociation of ribosomes into subunits is discussed. Process depends on dialysis or use of chelating agents. Operation of process and advantages over previous methods are outlined.

  20. Treatment of packaging board whitewater in anaerobic/aerobic biokidney.

    PubMed

    Alexandersson, T; Malmqvist, A

    2005-01-01

    Whitewater from production of packaging board was treated in a combined anaerobic/aerobic biokidney, both in laboratory scale and pilot plant experiments. Both the laboratory experiments and the pilot plant trial demonstrate that a combined anaerobic/aerobic process is suitable for treating whitewater from a packaging mill. It is also possible to operate the process at the prevailing whitewater temperature. In the laboratory under mesophilic conditions the maximal organic load was 12 kg COD/m3*d on the anaerobic reactor and 6.7 kg COD/m3*d on the aerobic reactor. This gave a hydraulic retention time, HRT, in the anaerobic reactor of 10 hours and 2 hours in the aerobic reactor. The reduction of COD was between 85 and 90% after the first stage and the total reduction was between 88 to 93%. Under thermophilic conditions in the laboratory the organic load was slightly lower than 9.6 COD/m3*d and between 10 and 16 COD/m3*d, respectively. The HRT was 16.5 and 3.4 hours and the removal was around 75% after the anaerobic reactor and 87% after the total process. For the pilot plant experiment at a mill the HRT in the anaerobic step varied between 3 and 17 hours and the corresponding organic load between 4 and 44 kg COD/m3*d. The HRT in the aerobic step varied between 1 and 6 hours and the organic load between 1.5 and 26 kg COD/m3*d. The removal of soluble organic matter was 78% in the anaerobic step and 86% after the combined treatment at the lowest loading level. The removal efficiency at the highest loading level was about 65% in the anaerobic step and 77% after the aerobic step. In the pilot plant trial the removal efficiency was not markedly affected by the variations in whitewater composition that were caused by change of production. The variations, however, made the manual control of the nutrient dosage inadequate and resulted in large variations in effluent nutrient concentration. This demonstrates the need for an automatic nutrient dosage system. The first step

  1. A KPI-based process monitoring and fault detection framework for large-scale processes.

    PubMed

    Zhang, Kai; Shardt, Yuri A W; Chen, Zhiwen; Yang, Xu; Ding, Steven X; Peng, Kaixiang

    2017-02-09

    Large-scale processes, consisting of multiple interconnected subprocesses, are commonly encountered in industrial systems, whose performance needs to be determined. A common approach to this problem is to use a key performance indicator (KPI)-based approach. However, the different KPI-based approaches are not developed with a coherent and consistent framework. Thus, this paper proposes a framework for KPI-based process monitoring and fault detection (PM-FD) for large-scale industrial processes, which considers the static and dynamic relationships between process and KPI variables. For the static case, a least squares-based approach is developed that provides an explicit link with least-squares regression, which gives better performance than partial least squares. For the dynamic case, using the kernel representation of each subprocess, an instrument variable is used to reduce the dynamic case to the static case. This framework is applied to the TE benchmark process and the hot strip mill rolling process. The results show that the proposed method can detect faults better than previous methods.

  2. Aerobic Exercise and Neurocognitive Performance: a Meta-Analytic Review of Randomized Controlled Trials

    PubMed Central

    Smith, Patrick J.; Blumenthal, James A.; Hoffman, Benson M.; Cooper, Harris; Strauman, Timothy A.; Welsh-Bohmer, Kathleen; Browndyke, Jeffrey N.; Sherwood, Andrew

    2010-01-01

    Objectives Although the effects of exercise on neurocognition have been the subject of several previous reviews and meta-analyses, they have been hampered by methodological shortcomings and are now outdated as a result of the recent publication of several large-scale randomized controlled trials (RCTs). Methods We conducted a systematic literature review of RCTs examining the association between aerobic exercise training on neurocognitive performance conducted between January, 1966 and July, 2009. Suitable studies were selected for inclusion according to the following criteria: randomized treatment allocation, mean age ≥ 18 years of age, duration of treatment > 1 month, incorporated aerobic exercise components, exercise training was supervised, the presence of a non-aerobic-exercise control group, and sufficient information to derive effect size (ES) data. Results Twenty-nine studies met inclusion criteria and were included in our analyses, representing data from 2,049 participants and 234 effect sizes. Individuals randomly assigned to receive aerobic exercise training demonstrated modest improvements in attention and processing speed (g = .158 [95% CI: .055 to .260], P = .003), executive function (g = .123 [95% CI: .021 to .225], P = .018), and memory (g = .128 [95% CI: .015 - .241], P = .026). Conclusions Aerobic exercise training is associated with modest improvements in attention and processing speed, executive function, and memory, although the effects of exercise on working memory are less consistent. Rigorous RCTs are needed with larger samples, appropriate controls, and longer follow-up periods. PMID:20223924

  3. Silicon biogeochemical processes in a large river (Cauvery, India)

    NASA Astrophysics Data System (ADS)

    Kameswari Rajasekaran, Mangalaa; Arnaud, Dapoigny; Jean, Riotte; Sarma Vedula, V. S. S.; Nittala, S. Sarma; Sankaran, Subramanian; Gundiga Puttojirao, Gurumurthy; Keshava, Balakrishna; Cardinal, Damien

    2016-04-01

    Cauvery may result from the successive dams along the main course which are expected to favor the retention of isotopically light Si isotopes in sediments via diatom uptake in reservoirs and/or, Si uptake by vegetation. Both processes likely result in heavier δ30Si-DSi downstream. In the estuary, the average δ30Si-DSi is 2.20±0.17 ‰ (n=11). There is a significant positive relationship between ASi contents and fucoxanthin (diatom marker pigment) (r=0.61, p<0.05, n=11) suggesting a significant control of diatoms on ASi. However a dominant mixing effect is observed in dissolved silicon with a strong positive relationship between 1/DSi and δ30Si-DSi (r=0.71, p<0.01, n=11). A comparative study with a west-flowing river, the Netravathi (southwest India) will be performed and presented during the session. We will also compare the Si isotopic signatures in Cauvery along the transect with focus on seasonal variability and on upstream vs. downstream large dams to strengthen interpretations.

  4. Summer Decay Processes in a Large Tabular Iceberg

    NASA Astrophysics Data System (ADS)

    Wadhams, P.; Wagner, T. M.; Bates, R.

    2012-12-01

    Summer Decay Processes in a Large Tabular Iceberg Peter Wadhams (1), Till J W Wagner(1) and Richard Bates(2) (1) Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA, UK (2) Scottish Oceans Institute, School of Geography and Geosciences, University of St Andrews, St. Andrews, Scotland KY16 9AL We present observational results from an experiment carried out during July-August 2012 on a giant grounded tabular iceberg off Baffin Island. The iceberg studied was part of the Petermann Ice Island B1 (PIIB1) which calved off the Petermann Glacier in NW Greenland in 2010. Since 2011 it has been aground in 100 m of water on the Baffin Island shelf at 69 deg 06'N, 66 deg 06'W. As part of the project a set of high resolution GPS sensors and tiltmeters was placed on the ice island to record rigid body motion as well as flexural responses to wind, waves, current and tidal forces, while a Waverider buoy monitored incident waves and swell. On July 31, 2012 a major breakup event was recorded, with a piece of 25,000 sq m surface area calving off the iceberg. At the time of breakup, GPS sensors were collecting data both on the main berg as well as on the newly calved piece, while two of us (PW and TJWW) were standing on the broken-out portion which rose by 0.6 m to achieve a new isostatic equilibrium. Crucially, there was no significant swell at the time of breakup, which suggests a melt-driven decay process rather than wave-driven flexural break-up. The GPS sensors recorded two disturbances during the hour preceding the breakup, indicative of crack growth and propagation. Qualitative observation during the two weeks in which our research ship was moored to, or was close to, the ice island edge indicates that an important mechanism for summer ablation is successive collapses of the overburden from above an unsupported wave cut, which creates a submerged ram fringing the berg. A model of buoyancy stresses induced by

  5. Decolorizing and detoxifying textile wastewater, containing both soluble and insoluble dyes, in a full scale combined anaerobic/aerobic system.

    PubMed

    Frijters, C T M J; Vos, R H; Scheffer, G; Mulder, R

    2006-03-01

    The wastewater originating from the bleaching and dyeing processes in the textile factory Ten Cate Protect in Nijverdal (the Netherlands) was successfully treated in a sequential anaerobic/aerobic system. In the system, a combination of an anaerobic 70-m3 fluidized bed reactor and a 450-m3 aerobic basin with integrated tilted plate settlers, 80-95% of the color was removed. The color was largely removed in the preacidification basin and the anaerobic reactor. Color, deriving from both reactive as well as disperse, was anaerobically removed, indicating that these type of dyes were reduced to colorless products. Interestingly, the vat dyes, the anthraquinones and indigoids, which were thought to be removed mainly aerobically, were largely anaerobically decolorized. Apparently the anaerobic system is capable of effectively removing the color of both soluble as insoluble dyes. The treated effluent of the sequential anaerobic/aerobic treatment showed no toxicity towards the bioluminescent bacterium Vibrio fisheri (EC20 (95%) > 45%). Partially bypassing the anaerobic stage resulted in increased toxicity (EC20 (95%) of 9% and 14%) in the effluent of the aerobic treatment and caused significant decrease of color removal. The results of this study show a main contribution of anaerobic treatment in decolorizing and detoxifying the textile wastewater in the sequential anaerobic/aerobic system.

  6. Managing Language Testing in Nigerian Large Classes: Processes and Prospects

    ERIC Educational Resources Information Center

    Abioye, Taiwo

    2010-01-01

    The demand for literacy in a developing country like Nigeria has multiple results such as the expansion, by leaps and bounds, of the average Nigerian classroom. This paper highlights the reasons for large classes in Nigerian secondary schools, the educational and psychological dimensions of language testing in large classes, the challenges of such…

  7. Investigation of transport processes in a large urban estuary

    NASA Astrophysics Data System (ADS)

    Caplow, T.; Schlosser, P.; Ho, D. T.; Santella, N.

    2003-04-01

    The Hudson River drains an area of 35 000 km^2 and terminates in a complex of waterways surrounding New York City. These waterways support the largest metropolitan area and third busiest seaport in the U.S., absorbing a large flux of industrial contaminants and wastewater, as well as accidental spills of oil and chemicals. Traditional approaches to the study of transport processes in New York Harbor include fluorescent dyes, moored current profilers, and numerical models, but these methods are limited by low temporal and spatial resolution and/or uncertain accuracy, particularly with regard to mixing. In July 2001, sulfur hexafluoride (SF_6) was injected into the Hudson River estuary near Newburgh, NY, about 100 km upstream from New York City. The resulting tracer patch was surveyed by boat (average resolution: 400 m) with an automated measurement system. After 13 days, the tracer patch was more than 100 km long. Net advection (0.5 km d-1), longitudinal dispersion (70 ± 4 m^2 s-1) and gas transfer velocity (6.5 ± 0.5 cm h-1) were determined from the tracer data. Tidal motions dominated river flow, and considerable quantities of tracer propagated upstream from the injection site. In July 2002, SF_6 was injected in the inner harbor, a complex of estuarine channels adjacent to the city. The tracer was tracked for 11 days. Due to tidal mixing, the shorter of two channels (9 km and 20 km) that connect with the outer harbor was the dominant seaward pathway, despite subtidal circulation in the opposite direction. As a result of gas transfer and seaward flushing, tracer mass in the inner harbor declined quasi-exponentially with a loss term of 0.29 ± 0.03 day-1. The loss term due to flushing alone (0.13 ± 0.02 day-1) indicated a mean residence time for water and solutes in the inner harbor of 8 days (without gas transfer). Further projects, including an investigation of wastewater fate, are planned within the lower estuary.

  8. Aerobic Activity--Do Physical Education Programs Provide Enough?

    ERIC Educational Resources Information Center

    McGing, Eileen

    1989-01-01

    High school physical education curricula should concentrate less on sport skill development and competition, and more on health-related fitness and aerobic activity. Results are reported from a study of the type and amount of aerobic exercise provided in 29 high school physical education programs in a large metropolitan area. (IAH)

  9. Manufacturing process to reduce large grain growth in zirconium alloys

    DOEpatents

    Rosecrans, P.M.

    1984-08-01

    It is an object of the present invention to provide a procedure for desensitizing zirconium-based alloys to large grain growth (LGG) during thermal treatment above the recrystallization temperature of the alloy. It is a further object of the present invention to provide a method for treating zirconium-based alloys which have been cold-worked in the range of 2 to 8% strain to reduce large grain growth. It is another object of the present invention to provide a method for fabricating a zirconium alloy clad nuclear fuel element wherein the zirconium clad is resistant to large grain growth.

  10. Automated Science Processing for the Fermi Large Area Telescope

    NASA Astrophysics Data System (ADS)

    Chiang, James

    2012-03-01

    The Large Area Telescope (LAT) onboard the Fermi γ-ray Space Telescope provides high sensitivity to emission from astronomical sources over a broad energy range (20MeV to >300 GeV) and has substantially improved spatial, energy, and timing resolution compared with previous observatories at these energies [4]. One of the LAT's most innovative features is that it performs continuous monitoring of the gamma-ray sky with all-sky coverage every 3 h. This survey strategy greatly enables the search for transient behavior from both previously known and unknown sources. In addition, the constant accumulation of data allows for increasingly improved measurements of persistent sources. These include the Milky Way Galaxy itself, which produces gamma-ray emission as a result from interactions of cosmic rays with gas in the Galaxy, and potential signals from candidate dark matter particles in the Milky Way and its neighboring galaxies. The automated science processing (ASP) functionality of the Fermi Instrument Science Operations Center (ISOC) is a part of the automated data pipeline that processes the raw data arriving from the spacecraft and puts it into a form amenable to scientific analysis. ASP operates at the end of the pipeline on the processed data and is intended to detect and characterize transient behavior (e.g., short time scale increases or “flares” in the gamma-ray flux) from astronomical sources. On detection of a flaring event, ASP will alert other observatories on a timely basis so that they may train their telescopes on the flaring source in order to detect possible correlated activity in other wavelength bands. Since the data from the LAT is archived and publicly available as soon as it is processed, ASP serves mainly to provide triggers for those follow-up observations; its estimates of the properties of the flaring sources (flux, spectral index, location) need not be the best possible, as subsequent off-line analysis can provide more refined

  11. Benchmarking processes for managing large international space programs

    NASA Technical Reports Server (NTRS)

    Mandell, Humboldt C., Jr.; Duke, Michael B.

    1993-01-01

    The relationship between management style and program costs is analyzed to determine the feasibility of financing large international space missions. The incorporation of management systems is considered to be essential to realizing low cost spacecraft and planetary surface systems. Several companies ranging from large Lockheed 'Skunk Works' to small companies including Space Industries, Inc., Rocket Research Corp., and Orbital Sciences Corp. were studied. It is concluded that to lower the prices, the ways in which spacecraft and hardware are developed must be changed. Benchmarking of successful low cost space programs has revealed a number of prescriptive rules for low cost managements, including major changes in the relationships between the public and private sectors.

  12. Transcriptional Regulation of Aerobic Metabolism in Pichia pastoris Fermentation

    PubMed Central

    Zhang, Biao; Li, Baizhi; Chen, Dai; Zong, Jie; Sun, Fei; Qu, Huixin; Liang, Chongyang

    2016-01-01

    In this study, we investigated the classical fermentation process in Pichia pastoris based on transcriptomics. We utilized methanol in pichia yeast cell as the focus of our study, based on two key steps: limiting carbon source replacement (from glycerol to methonal) and fermentative production of exogenous proteins. In the former, the core differential genes in co-expression net point to initiation of aerobic metabolism and generation of peroxisome. The transmission electron microscope (TEM) results showed that yeast gradually adapted methanol induction to increased cell volume, and decreased density, via large number of peroxisomes. In the fermentative production of exogenous proteins, the Gene Ontology (GO) mapping results show that PAS_chr2-1_0582 played a vital role in regulating aerobic metabolic drift. In order to confirm the above results, we disrupted PAS_chr2-1_0582 by homologous recombination. Alcohol consumption was equivalent to one fifth of the normal control, and fewer peroxisomes were observed in Δ0582 strain following methanol induction. In this study we determined the important core genes and GO terms regulating aerobic metabolic drift in Pichia, as well as developing new perspectives for the continued development within this field. PMID:27537181

  13. Really big data: Processing and analysis of large datasets

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Modern animal breeding datasets are large and getting larger, due in part to the recent availability of DNA data for many animals. Computational methods for efficiently storing and analyzing those data are under development. The amount of storage space required for such datasets is increasing rapidl...

  14. Depth gradients in food web processes linking large lake habitats

    EPA Science Inventory

    In large lakes around the world, shifts in ecological communities are often associated with water depth. This suggests that there may be concomitant changes in patterns of resource allocation. Using Lake Superior as an example, we explored this idea through stable isotope analyse...

  15. Manufacturing process to reduce large grain growth in zirconium alloys

    DOEpatents

    Rosecrans, Peter M.

    1987-01-01

    A method of treating cold-worked zirconium alloys to reduce large grain gth during thermal treatment at temperatures above the recrystallization temperature of the alloy comprising heating the cold-worked alloy between about 1300.degree.-1350.degree. F. for 1 to 3 hours prior to treatment above its recrystallization temperature.

  16. Numerical modeling of a large deformation thermoforming process

    SciTech Connect

    Schrank, M.G.

    1988-04-01

    A numerical solution, using finite element methods, is presented for the simulation of a blow-molding process used to form a thermoplastic polymer (polyethylene terephthalate). The constitutive relationship employed in the analysis is a modification of the creep power law, allowing both strain hardening and strain rate hardening of the material. Analytical results compare well with experimental data for both rate of deformation during the forming process and strain distribution in the final formed configuration. 15 figs.

  17. Measurement Agreement between Estimates of Aerobic Fitness in Youth: The Impact of Body Mass Index

    ERIC Educational Resources Information Center

    Saint-Maurice, Pedro F.; Welk, Gregory J.; Laurson, Kelly R.; Brown, Dale D.

    2014-01-01

    Purpose: The purpose of this study was to examine the impact of body mass index (BMI) on the agreement between aerobic capacity estimates from different Progressive Aerobic Cardiorespiratory Endurance Run (PACER) equations and the Mile Run Test. Method: The agreement between 2 different tests of aerobic capacity was examined on a large data set…

  18. Dance--Aerobic and Anaerobic.

    ERIC Educational Resources Information Center

    Cohen, Arlette

    1984-01-01

    This article defines and explains aerobic exercise and its effects on the cardiovascular system. Various studies on dancers are cited indicating that dance is an anaerobic activity with some small degree of aerobic benefit. (DF)

  19. Manufacturing Process Simulation of Large-Scale Cryotanks

    NASA Technical Reports Server (NTRS)

    Babai, Majid; Phillips, Steven; Griffin, Brian; Munafo, Paul M. (Technical Monitor)

    2002-01-01

    NASA's Space Launch Initiative (SLI) is an effort to research and develop the technologies needed to build a second-generation reusable launch vehicle. It is required that this new launch vehicle be 100 times safer and 10 times cheaper to operate than current launch vehicles. Part of the SLI includes the development of reusable composite and metallic cryotanks. The size of these reusable tanks is far greater than anything ever developed and exceeds the design limits of current manufacturing tools. Several design and manufacturing approaches have been formulated, but many factors must be weighed during the selection process. Among these factors are tooling reachability, cycle times, feasibility, and facility impacts. The manufacturing process simulation capabilities available at NASA's Marshall Space Flight Center have played a key role in down selecting between the various manufacturing approaches. By creating 3-D manufacturing process simulations, the varying approaches can be analyzed in a virtual world before any hardware or infrastructure is built. This analysis can detect and eliminate costly flaws in the various manufacturing approaches. The simulations check for collisions between devices, verify that design limits on joints are not exceeded, and provide cycle times which aid in the development of an optimized process flow. In addition, new ideas and concerns are often raised after seeing the visual representation of a manufacturing process flow. The output of the manufacturing process simulations allows for cost and safety comparisons to be performed between the various manufacturing approaches. This output helps determine which manufacturing process options reach the safety and cost goals of the SLI.

  20. Manufacturing Process Simulation of Large-Scale Cryotanks

    NASA Technical Reports Server (NTRS)

    Babai, Majid; Phillips, Steven; Griffin, Brian

    2003-01-01

    NASA's Space Launch Initiative (SLI) is an effort to research and develop the technologies needed to build a second-generation reusable launch vehicle. It is required that this new launch vehicle be 100 times safer and 10 times cheaper to operate than current launch vehicles. Part of the SLI includes the development of reusable composite and metallic cryotanks. The size of these reusable tanks is far greater than anything ever developed and exceeds the design limits of current manufacturing tools. Several design and manufacturing approaches have been formulated, but many factors must be weighed during the selection process. Among these factors are tooling reachability, cycle times, feasibility, and facility impacts. The manufacturing process simulation capabilities available at NASA.s Marshall Space Flight Center have played a key role in down selecting between the various manufacturing approaches. By creating 3-D manufacturing process simulations, the varying approaches can be analyzed in a virtual world before any hardware or infrastructure is built. This analysis can detect and eliminate costly flaws in the various manufacturing approaches. The simulations check for collisions between devices, verify that design limits on joints are not exceeded, and provide cycle times which aide in the development of an optimized process flow. In addition, new ideas and concerns are often raised after seeing the visual representation of a manufacturing process flow. The output of the manufacturing process simulations allows for cost and safety comparisons to be performed between the various manufacturing approaches. This output helps determine which manufacturing process options reach the safety and cost goals of the SLI. As part of the SLI, The Boeing Company was awarded a basic period contract to research and propose options for both a metallic and a composite cryotank. Boeing then entered into a task agreement with the Marshall Space Flight Center to provide manufacturing

  1. Implementation of Aerobic Programs.

    ERIC Educational Resources Information Center

    American Alliance for Health, Physical Education, Recreation and Dance (AAHPERD).

    This information is intended for health professionals interested in implementing aerobic exercise programs in public schools, institutions of higher learning, and business and industry workplaces. The papers are divided into three general sections. The introductory section presents a basis for adhering to a health fitness lifestyle, using…

  2. Aerobic Dance in Public Schools.

    ERIC Educational Resources Information Center

    Chiles, Barbara Ann; Moore, Suzanne

    1981-01-01

    Aerobic dance offers a challenging workout in a social atmosphere. Though some physical education instructors tend to exclude dance units from the curriculum, most could teach aerobic dance if they had a basic knowledge of aerobic routines. The outline for a unit to be used in the class is presented. (JN)

  3. Natural Language Processing: Toward Large-Scale, Robust Systems.

    ERIC Educational Resources Information Center

    Haas, Stephanie W.

    1996-01-01

    Natural language processing (NLP) is concerned with getting computers to do useful things with natural language. Major applications include machine translation, text generation, information retrieval, and natural language interfaces. Reviews important developments since 1987 that have led to advances in NLP; current NLP applications; and problems…

  4. Advanced Instruction: Facilitation of Individual Learning Processes in Large Groups

    ERIC Educational Resources Information Center

    Putz, Claus; Intveen, Geesche

    2009-01-01

    By supplying various combinations of advanced instructions and different forms of exercises individual learning processes within the impartation of basic knowledge can be activated and supported at best. The fundamentals of our class "Introduction to spatial-geometric cognition using CAD" are constructional inputs, which systematically induce the…

  5. Processing large remote sensing image data sets on Beowulf clusters

    USGS Publications Warehouse

    Steinwand, Daniel R.; Maddox, Brian; Beckmann, Tim; Schmidt, Gail

    2003-01-01

    High-performance computing is often concerned with the speed at which floating- point calculations can be performed. The architectures of many parallel computers and/or their network topologies are based on these investigations. Often, benchmarks resulting from these investigations are compiled with little regard to how a large dataset would move about in these systems. This part of the Beowulf study addresses that concern by looking at specific applications software and system-level modifications. Applications include an implementation of a smoothing filter for time-series data, a parallel implementation of the decision tree algorithm used in the Landcover Characterization project, a parallel Kriging algorithm used to fit point data collected in the field on invasive species to a regular grid, and modifications to the Beowulf project's resampling algorithm to handle larger, higher resolution datasets at a national scale. Systems-level investigations include a feasibility study on Flat Neighborhood Networks and modifications of that concept with Parallel File Systems.

  6. Nanomaterials processing toward large-scale flexible/stretchable electronics

    NASA Astrophysics Data System (ADS)

    Takahashi, Toshitake

    In recent years, there has been tremendous progress in large-scale mechanically flexible electronics, where electrical components are fabricated on non-crystalline substrates such as plastics and glass. These devices are currently serving as the basis for various applications such as flat-panel displays, smart cards, and wearable electronics. In this thesis, a promising approach using chemically synthesized nanomaterials is explored to overcome various obstacles current technology faces in this field. Here, we use chemically synthesized semiconducting nanowires (NWs) including group IV (Si, Ge), III-V (InAs) and II-IV (CdS, CdSe) NWs, and semiconductor-enriched SWNTs (99 % purity), and developed reliable, controllable, and more importantly uniform assembly methods on 4-inch wafer-scale flexible substrates in the form of either parallel NW arrays or SWNT random networks, which act as the active components in thin film transistors (TFTs). Thusly obtained TFTs composed of nanomaterials show respectable electrical and optical properties such as 1) cut-off frequency, ft ~ 1 GHz and maximum frequency of oscillation, fmax ~ 1.8 GHz from InAs parallel NW array TFTs with channel length of ~ 1.5 μm, 2) photodetectors covering visible wavelengths (500-700 nm) using compositionally graded CdSxSe1-x (0 < x < 1) parallel NW arrays, and 3) carrier mobility of ~ 20 cm2/Vs, which is an order of magnitude larger than conventional TFT materials such as a-Si and organic semiconductors, without sacrificing current on/off ratio (Ion/Ioff ~ 104) from SWNT network TFTs. The capability to uniformly assemble nanomaterials over large-scale flexible substrates enables us to use them for more sophisticated applications. Artificial electronic skin (e-skin) is demonstrated by laminating pressure sensitive rubber on top of nanomaterial-based active matrix backplanes. Furthermore, an x-ray imaging device is also achieved by combining organic photodiodes with this backplane technology.

  7. Processing method and process modeling of large aperture transparent magnesium aluminate spinel domes

    NASA Astrophysics Data System (ADS)

    Yu, Jian; McWilliams, Brandon; Kilczewski, Steven; Gilde, Gary; Lidie, Ashley; Sands, James

    2009-05-01

    Polycrystalline spinel serves as an alternative to materials such as sapphire and magnesium fluoride that are currently being used in electromagnetic window applications such as missile domes, where high strength, high hardness and high transmittance in the visible and infrared spectra are required. The cubic crystal lattice of spinel imparts an isotropy to the bulk optical property, which eliminates optical distortion due to birefringence that occurs in sapphire and other non-cubic materials. The current study is to find a reliable manufacturing process to produce large magnesium aluminate spinel domes from powder consolidation efficiently. A binder-less dry ball milling process was used to deflocculate the spinel powder to increase its fluidity in an effort to ease the shape-forming. Dry ball milling time trials were conducted at several intervals to determine the appropriate level of time required to break up both the hard and soft agglomerates associated with the virgin spinel powder. The common problems encountered in dry powder shape-forming are crack growth and delamination of the green body during cold isostatic pressing (CIPing). The cracking and the delamination are due to the buildup of stress gradients on the green body that are created by the frictional force between the powder and the die wall or mold wall. To understand the stresses during the CIPing process, a finite element analysis of stresses on the green body was conducted. The simulation was used to evaluate the effect of die tooling and process characteristics on the development of stress gradients in the green body dome. Additionally, the effect of friction between the die wall and powder was examined by the simulation. It was found that by mitigating the frictional forces, cracking and delamination on the green body could be eliminated. A stepped-pressure CIPing technique was developed to reduce stress gradient build-up during CIPing. Also, oleic acid lubricant was applied to the die wall to

  8. Reducing aeration energy consumption in a large-scale membrane bioreactor: Process simulation and engineering application.

    PubMed

    Sun, Jianyu; Liang, Peng; Yan, Xiaoxu; Zuo, Kuichang; Xiao, Kang; Xia, Junlin; Qiu, Yong; Wu, Qing; Wu, Shijia; Huang, Xia; Qi, Meng; Wen, Xianghua

    2016-04-15

    Reducing the energy consumption of membrane bioreactors (MBRs) is highly important for their wider application in wastewater treatment engineering. Of particular significance is reducing aeration in aerobic tanks to reduce the overall energy consumption. This study proposed an in situ ammonia-N-based feedback control strategy for aeration in aerobic tanks; this was tested via model simulation and through a large-scale (50,000 m(3)/d) engineering application. A full-scale MBR model was developed based on the activated sludge model (ASM) and was calibrated to the actual MBR. The aeration control strategy took the form of a two-step cascaded proportion-integration (PI) feedback algorithm. Algorithmic parameters were optimized via model simulation. The strategy achieved real-time adjustment of aeration amounts based on feedback from effluent quality (i.e., ammonia-N). The effectiveness of the strategy was evaluated through both the model platform and the full-scale engineering application. In the former, the aeration flow rate was reduced by 15-20%. In the engineering application, the aeration flow rate was reduced by 20%, and overall specific energy consumption correspondingly reduced by 4% to 0.45 kWh/m(3)-effluent, using the present practice of regulating the angle of guide vanes of fixed-frequency blowers. Potential energy savings are expected to be higher for MBRs with variable-frequency blowers. This study indicated that the ammonia-N-based aeration control strategy holds promise for application in full-scale MBRs.

  9. LSSA large area silicon sheet task continuous Czochralski process development

    NASA Technical Reports Server (NTRS)

    Rea, S. N.

    1978-01-01

    A Czochralski crystal growing furnace was converted to a continuous growth facility by installation of a premelter to provide molten silicon flow into the primary crucible. The basic furnace is operational and several trial crystals were grown in the batch mode. Numerous premelter configurations were tested both in laboratory-scale equipment as well as in the actual furnace. The best arrangement tested to date is a vertical, cylindrical graphite heater containing small fused silicon test tube liner in which the incoming silicon is melted and flows into the primary crucible. Economic modeling of the continuous Czochralski process indicates that for 10 cm diameter crystal, 100 kg furnace runs of four or five crystals each are near-optimal. Costs tend to asymptote at the 100 kg level so little additional cost improvement occurs at larger runs. For these conditions, crystal cost in equivalent wafer area of around $20/sq m exclusive of polysilicon and slicing was obtained.

  10. Large-scale superconducting separator for Kaolin processing

    SciTech Connect

    Winters, A.J, Jr. ); Selvaggi, J.A. )

    1990-01-01

    Currently, high gradient magnetic separators (HGMSs) are used almost exclusively by the clay processing industry, particularly in producing an extremely white kaolin for the paper, coatings and rubber industries where a bright additive is desirable. As mined, the clay is a light cream color-not white. Many of these impurities can be removed chemically using a reducing agent such as sodium hydrosulfite in low pH, sulfuric acid, and alum. High purity, however, can be obtained by removing trace amounts of paramagnetic particles (100% finer than 2 {mu}m). This is accomplished by separating these particles from 28 wt% kaolin in a water slurry retaining them on magnetic wool, which is then periodically regenerated.

  11. Large-scale ordering of nanoparticles using viscoelastic shear processing

    NASA Astrophysics Data System (ADS)

    Zhao, Qibin; Finlayson, Chris E.; Snoswell, David R. E.; Haines, Andrew; Schäfer, Christian; Spahn, Peter; Hellmann, Goetz P.; Petukhov, Andrei V.; Herrmann, Lars; Burdet, Pierre; Midgley, Paul A.; Butler, Simon; Mackley, Malcolm; Guo, Qixin; Baumberg, Jeremy J.

    2016-06-01

    Despite the availability of elaborate varieties of nanoparticles, their assembly into regular superstructures and photonic materials remains challenging. Here we show how flexible films of stacked polymer nanoparticles can be directly assembled in a roll-to-roll process using a bending-induced oscillatory shear technique. For sub-micron spherical nanoparticles, this gives elastomeric photonic crystals termed polymer opals showing extremely strong tunable structural colour. With oscillatory strain amplitudes of 300%, crystallization initiates at the wall and develops quickly across the bulk within only five oscillations. The resulting structure of random hexagonal close-packed layers is improved by shearing bidirectionally, alternating between two in-plane directions. Our theoretical framework indicates how the reduction in shear viscosity with increasing order of each layer accounts for these results, even when diffusion is totally absent. This general principle of shear ordering in viscoelastic media opens the way to manufacturable photonic materials, and forms a generic tool for ordering nanoparticles.

  12. Large-scale ordering of nanoparticles using viscoelastic shear processing

    PubMed Central

    Zhao, Qibin; Finlayson, Chris E.; Snoswell, David R. E.; Haines, Andrew; Schäfer, Christian; Spahn, Peter; Hellmann, Goetz P.; Petukhov, Andrei V.; Herrmann, Lars; Burdet, Pierre; Midgley, Paul A.; Butler, Simon; Mackley, Malcolm; Guo, Qixin; Baumberg, Jeremy J.

    2016-01-01

    Despite the availability of elaborate varieties of nanoparticles, their assembly into regular superstructures and photonic materials remains challenging. Here we show how flexible films of stacked polymer nanoparticles can be directly assembled in a roll-to-roll process using a bending-induced oscillatory shear technique. For sub-micron spherical nanoparticles, this gives elastomeric photonic crystals termed polymer opals showing extremely strong tunable structural colour. With oscillatory strain amplitudes of 300%, crystallization initiates at the wall and develops quickly across the bulk within only five oscillations. The resulting structure of random hexagonal close-packed layers is improved by shearing bidirectionally, alternating between two in-plane directions. Our theoretical framework indicates how the reduction in shear viscosity with increasing order of each layer accounts for these results, even when diffusion is totally absent. This general principle of shear ordering in viscoelastic media opens the way to manufacturable photonic materials, and forms a generic tool for ordering nanoparticles. PMID:27255808

  13. Assessing Enhanced Anaerobic and Intrinsic Aerobic Biodegradation of Trichloroethene

    NASA Astrophysics Data System (ADS)

    Sorenson, K. S.; Ely, R. L.; Martin, J. P.; Alvarez-Cohen, L.; Kauffman, M. E.

    2001-12-01

    Biodegradation of chloroethenes can proceed either anaerobically or aerobically; however, the techniques for monitoring the two pathways are quite different. At the Idaho National Engineering and Environmental Laboratory's Test Area North (TAN, a combination of anaerobic and aerobic biodegradation of trichloroethene (TCE) is being employed for restoration of a large plume of contaminated groundwater. During stimulation of anaerobic biodegradation of TCE through lactate addition, several assessment tools have proven effective for various objectives. Monitoring TCE and its lesser chlorinated degradation products provides a straightforward assessment tool for the occurrence of degradation. It does not, however, provide information regarding the potential for reductive dechlorination, nor progress from less suitable to more suitable conditions. A technique for obtaining this information is monitoring redox-sensitive geochemical parameters such as dissolved iron, sulfate, methane, and oxidation-reduction potential. This approach was demonstrated by the strong correlation of steps in the reductive dechlorination pathway to redox conditions at the TAN site. Yet another tool is required to determine adequacy of conditions for efficient dechlorination. Dechlorination efficiency appears to be dependent upon the predominant electron donor utilization (or fermentation) process occurring at any given time, an observation consistent with thermodynamic considerations. Thus, monitoring of added electron donor and intermediate product concentrations can help determine an efficient operations strategy. One final tool demonstrated at the TAN site was monitoring stable carbon isotope ratios. As TCE was dechlorinated, a clear fractionation occurred from cis-dichloroethene to vinyl chloride, and from vinyl chloride to ethene. This fractionation provides a clear signature of reductive dechlorination. Assessment of aerobic biodegradation of chloroethenes at TAN is more challenging because

  14. Enhancing Cognitive Training Through Aerobic Exercise After a First Schizophrenia Episode: Theoretical Conception and Pilot Study.

    PubMed

    Nuechterlein, Keith H; Ventura, Joseph; McEwen, Sarah C; Gretchen-Doorly, Denise; Vinogradov, Sophia; Subotnik, Kenneth L

    2016-07-01

    Cognitive training (CT) and aerobic exercise have separately shown promise for improving cognitive deficits in schizophrenia. Aerobic exercise releases brain-derived neurotrophic factor, which promotes synaptic plasticity and neurogenesis. Thus, aerobic exercise provides a neurotrophic platform for neuroplasticity-based CT. The combination of aerobic exercise and CT may yield more robust effects than CT alone, particularly in the initial course of schizophrenia. In a pilot study, 7 patients with a recent onset of schizophrenia were assigned to Cognitive Training & Exercise (CT&E) and 9 to CT alone for a 10-week period. Posit Science programs were used for CT. Neurocognitive training focused on tuning neural circuits related to perceptual processing and verbal learning and memory. Social cognitive training used the same learning principles with social and affective stimuli. Both groups participated in these training sessions 2d/wk, 2h/d. The CT&E group also participated in an aerobic conditioning program for 30 minutes at our clinic 2d/wk and at home 2d/wk. The effect size for improvement in the MATRICS Consensus Cognitive Battery Overall Composite score for CT&E patients relative to CT patients was large. Functional outcome, particularly independent living skills, also tended to improve more in the CT&E than in the CT group. Muscular endurance, cardiovascular fitness, and diastolic blood pressure also showed relative improvement in the CT&E compared to the CT group. These encouraging pilot study findings support the promise of combining CT and aerobic exercise to improve the early course of schizophrenia.

  15. Aerobic Stability and Effects of Yeasts during Deterioration of Non-fermented and Fermented Total Mixed Ration with Different Moisture Levels

    PubMed Central

    Hao, W.; Wang, H. L.; Ning, T. T.; Yang, F. Y.; Xu, C. C.

    2015-01-01

    The present experiment evaluated the influence of moisture level and anaerobic fermentation on aerobic stability of total mixed ration (TMR). The dynamic changes in chemical composition and microbial population that occur after air exposure were examined, and the species of yeast associated with the deterioration process were also identified in both non-fermented and fermented TMR to deepen the understanding of aerobic deterioration. The moisture levels of TMR in this experiment were adjusted to 400 g/kg (low moisture level, LML), 450 g/kg (medium moisture level, MML), and 500 g/kg (high moisture level, HML), and both non-fermented and 56-d-fermented TMR were subjected to air exposure to determine aerobic stability. Aerobic deterioration resulted in high losses of nutritional components and largely reduced dry matter digestibility. Non-fermented TMR deteriorated during 48 h of air exposure and the HML treatment was more aerobically unstable. On dry matter (DM) basis, yeast populations significantly increased from 107 to 1010 cfu/g during air exposure, and Candida ethanolica was the predominant species during deterioration in non-fermented TMR. Fermented TMR exhibited considerable resistance to aerobic deterioration. Spoilage was only observed in the HML treatment and its yeast population increased dramatically to 109 cfu/g DM when air exposure progressed to 30 d. Zygosaccharomyces bailii was the sole yeast species isolated when spoilage occurred. These results confirmed that non-fermented and fermented TMR with a HML are more prone to spoilage, and fermented TMR has considerable resistance to aerobic deterioration. Yeasts can trigger aerobic deterioration in both non-fermented and fermented TMR. C. ethanolica may be involved in the spoilage of non-fermented TMR and the vigorous growth of Z. bailii can initiate aerobic deterioration in fermented TMR. PMID:25925059

  16. Anaerobic and aerobic transformation of TNT

    SciTech Connect

    Kulpa, C.F.; Boopathy, R.; Manning, J.

    1996-12-31

    Most studies on the microbial metabolism of nitroaromatic compounds have used pure cultures of aerobic microorganisms. In many cases, attempts to degrade nitroaromatics under aerobic conditions by pure cultures result in no mineralization and only superficial modifications of the structure. However, mixed culture systems properly operated result in the transformation of 2,4,6-trinitrotoluene (TNT) and in some cases mineralization of TNT occurs. In this paper, the mixed culture system is described with emphasis on intermediates and the characteristics of the aerobic microbial process including the necessity for a co-substrate. The possibility of removing TNT under aerobic/anoxic conditions is described in detail. Another option for the biodegradation of TNT and nitroaromatics is under anaerobic, sulfate reducing conditions. In this instance, the nitroaromatic compounds undergo a series of reductions with the formation of amino compounds. TNT under sulfate reducing conditions is reduced to triaminotoluene presumably by the enzyme nitrite reductase, which is commonly found in many Desulfovibrio spp. The removal of nitro groups from TNT is achieved by a series of reductive reactions with the formation of ammonia and toluene by Desulfovibrio sp. (B strain). These metabolic processes could be applied to other nitroaromatic compounds like nitrobenzene, nitrobenzoic acids, nitrophenols, and aniline. The data supporting the anaerobic transformation of TNT under different growth condition are reviewed in this report.

  17. Aerobic and two-stage anaerobic-aerobic sludge digestion with pure oxygen and air aeration.

    PubMed

    Zupancic, Gregor D; Ros, Milenko

    2008-01-01

    The degradability of excess activated sludge from a wastewater treatment plant was studied. The objective was establishing the degree of degradation using either air or pure oxygen at different temperatures. Sludge treated with pure oxygen was degraded at temperatures from 22 degrees C to 50 degrees C while samples treated with air were degraded between 32 degrees C and 65 degrees C. Using air, sludge is efficiently degraded at 37 degrees C and at 50-55 degrees C. With oxygen, sludge was most effectively degraded at 38 degrees C or at 25-30 degrees C. Two-stage anaerobic-aerobic processes were studied. The first anaerobic stage was always operated for 5 days HRT, and the second stage involved aeration with pure oxygen and an HRT between 5 and 10 days. Under these conditions, there is 53.5% VSS removal and 55.4% COD degradation at 15 days HRT - 5 days anaerobic, 10 days aerobic. Sludge digested with pure oxygen at 25 degrees C in a batch reactor converted 48% of sludge total Kjeldahl nitrogen to nitrate. Addition of an aerobic stage with pure oxygen aeration to the anaerobic digestion enhances ammonium nitrogen removal. In a two-stage anaerobic-aerobic sludge digestion process within 8 days HRT of the aerobic stage, the removal of ammonium nitrogen was 85%.

  18. Nitrification and aerobic denitrification in anoxic-aerobic sequencing batch reactor.

    PubMed

    Alzate Marin, Juan C; Caravelli, Alejandro H; Zaritzky, Noemí E

    2016-01-01

    The aim of this study was to evaluate the feasibility of achieving nitrogen (N) removal using a lab-scale sequencing batch reactor (SBR) exposed to anoxic/aerobic (AN/OX) phases, focusing to achieve aerobic denitrification. This process will minimize emissions of N2O greenhouse gas. The effects of different operating parameters on the reactor performance were studied: cycle duration, AN/OX ratio, pH, dissolved oxygen concentration (DOC), and organic load. The highest inorganic N removal (NiR), close to 70%, was obtained at pH=7.5, low organic load (440mgCOD/(Lday)) and high aeration given by 12h cycle, AN/OX ratio=0.5:1.0 and DOC higher than 4.0mgO2/L. Nitrification followed by high-rate aerobic denitrification took place during the aerobic phase. Aerobic denitrification could be attributed to Tetrad-forming organisms (TFOs) with phenotype of glycogen accumulating organisms using polyhydroxyalkanoate and/or glycogen storage. The proposed AN/OX system constitutes an eco-friendly N removal process providing N2 as the end product.

  19. Development of large area, low-cost, solar cell processing sequence

    NASA Technical Reports Server (NTRS)

    Chitre, S.; Donon, J.

    1981-01-01

    A cost effective process based on state-of-the-art technology has been developed for the production of large-area (55 sq cm and larger) solar cells. The process is capable of providing silicon and polysilicon cell efficiencies in excess of 10% at an overall cost of 12 c/watt in 1980 dollars. The process provides large throughputs and is suitable for complete automation with high yields. Various stages of the process development are discussed.

  20. Sludge minimization using aerobic/anoxic treatment technology

    SciTech Connect

    Mines, R.O. Jr.; Kalch, R.S.

    1999-07-01

    The objective of this investigation was to demonstrate through a bench-scale study that using an aerobic/anoxic sequence to treat wastewater and biosolids could significantly reduce the production of biosolids (sludge). A bench-scale activated sludge reactor and anoxic digester were operated for approximately three months. The process train consisted of a completely-mixed aerobic reactor with wasting of biosolids to an anoxic digester for stabilization. The system was operated such that biomass produced in the aerobic activated sludge process was wasted to the anoxic digester; and biomass produced in the anoxic digester was wasted back to the activated sludge process. A synthetic wastewater consisting of bacto-peptone nutrient broth was fed to the liquid process train. Influent and effluent to the aerobic biological process train were analytically tested, as were the contents of mixed liquor in the aerobic reactor and anoxic digester. Overall removal efficiencies for the activated sludge process with regard to COD, TKN, NH{sub 3}-N, and alkalinity averaged 91, 89, 98, and 38%, respectively. The overall average sludge production for the aerobic/anoxic process was 24% less than the overall average sludge production from a conventional activated sludge bench-scale system fed the same substrate and operated under similar mean cell residence times.

  1. Aerobic landfill bioreactor

    SciTech Connect

    Hudgins, Mark P; Bessette, Bernard J; March, John; McComb, Scott T.

    2000-01-01

    The present invention includes a method of decomposing municipal solid waste (MSW) within a landfill by converting the landfill to aerobic degradation in the following manner: (1) injecting air via the landfill leachate collection system (2) injecting air via vertical air injection wells installed within the waste mass; (3) applying leachate to the waste mass using a pressurized drip irrigation system; (4) allowing landfill gases to vent; and (5) adjusting air injection and recirculated leachate to achieve a 40% to 60% moisture level and a temperature between 120.degree. F. and 140.degree. F. in steady state.

  2. Aerobic landfill bioreactor

    SciTech Connect

    Hudgins, Mark P; Bessette, Bernard J; March, John C; McComb, Scott T.

    2002-01-01

    The present invention includes a system of decomposing municipal solid waste (MSW) within a landfill by converting the landfill to aerobic degradation in the following manner: (1) injecting air via the landfill leachate collection system (2) injecting air via vertical air injection wells installed within the waste mass; (3) applying leachate to the waste mass using a pressurized drip irrigation system; (4) allowing landfill gases to vent; and (5) adjusting air injection and recirculated leachate to achieve a 40% to 60% moisture level and a temperature between 120.degree. F. and 140.degree. F. in steady state.

  3. Aerobic landfill bioreactor

    SciTech Connect

    Hudgins, M.P.; Bessette, B.J.; March, J.; McComb, S.T.

    2000-02-15

    The present invention includes a method of decomposing municipal solid waste (MSW) within a landfill by converting the landfill to aerobic degradation in the following manner: (1) injecting air via the landfill leachate collection system (2) injecting air via vertical air injection wells installed within the waste mass; (3) applying leachate to the waste mass using a pressurized drip irrigation system; (4) allowing landfill gases to vent; and (5) adjusting air injection and recirculated leachate to achieve a 40% to 60% moisture level and a temperature between 120 F and 140 F in steady state.

  4. Aerobic fitness testing: an update.

    PubMed

    Stevens, N; Sykes, K

    1996-12-01

    This study confirms that all three tests are reliable tools for the assessment of cardiorespiratory fitness and the prediction of aerobic capacity. While this particular study consisted of active, youthful subjects, subsequent studies at University College Chester have found similar findings with larger databases and a wider cross-section of subjects. The Astrand cycle test and Chester step test are submaximal tests with error margins of 5-15 per cent and therefore, not as precise as maximal testing. However, they still give a reasonably accurate reflection of an individual's fitness without the cost, time, effort and risk on the part of the subject. The bleep test is a low-cost maximal test designed for well-motivated, active individuals who are used to running to physical exhaustion. Used on other groups, results will not accurately reflect cardiorespiratory fitness values. While all three tests have inherent advantages and disadvantages, perhaps the most important factors are the knowledge and skills of the tester. Without a sound understanding of the physiological principles underlying these tests, and the ability to conduct an accurate assessment and evaluation of results in a knowledgeable and meaningful way, then the credibility of the tests and the results become suspect. However, used correctly, aerobic capacity tests can provide valuable baseline data about the fitness levels of individuals and data from which exercise programmes may be developed. The tests also enable fitness improvements to be monitored, help to motivate participants by establishing reasonable and achievable goals, assist in risk stratification and facilitate participants' education about the importance of physical fitness for work and for life. Since this study was completed, further tests have been repeated on 140 subjects of a wider age and ability range. This large database confirms the results found in this study.

  5. Development and Applications of a Modular Parallel Process for Large Scale Fluid/Structures Problems

    NASA Technical Reports Server (NTRS)

    Guruswamy, Guru P.; Kwak, Dochan (Technical Monitor)

    2002-01-01

    A modular process that can efficiently solve large scale multidisciplinary problems using massively parallel supercomputers is presented. The process integrates disciplines with diverse physical characteristics by retaining the efficiency of individual disciplines. Computational domain independence of individual disciplines is maintained using a meta programming approach. The process integrates disciplines without affecting the combined performance. Results are demonstrated for large scale aerospace problems on several supercomputers. The super scalability and portability of the approach is demonstrated on several parallel computers.

  6. Development and Applications of a Modular Parallel Process for Large Scale Fluid/Structures Problems

    NASA Technical Reports Server (NTRS)

    Guruswamy, Guru P.; Byun, Chansup; Kwak, Dochan (Technical Monitor)

    2001-01-01

    A modular process that can efficiently solve large scale multidisciplinary problems using massively parallel super computers is presented. The process integrates disciplines with diverse physical characteristics by retaining the efficiency of individual disciplines. Computational domain independence of individual disciplines is maintained using a meta programming approach. The process integrates disciplines without affecting the combined performance. Results are demonstrated for large scale aerospace problems on several supercomputers. The super scalability and portability of the approach is demonstrated on several parallel computers.

  7. Exercise, Animal Aerobics, and Interpretation?

    ERIC Educational Resources Information Center

    Oliver, Valerie

    1996-01-01

    Describes an aerobic activity set to music for children that mimics animal movements. Example exercises include walking like a penguin or jumping like a cricket. Stresses basic aerobic principles and designing the program at the level of children's motor skills. Benefits include reaching people who normally don't visit nature centers, and bridging…

  8. Effects of carbon sources on the enrichment of halophilic polyhydroxyalkanoate-storing mixed microbial culture in an aerobic dynamic feeding process

    PubMed Central

    Cui, You-Wei; Zhang, Hong-Yu; Lu, Peng-Fei; Peng, Yong-Zhen

    2016-01-01

    Microbial polyhydroxyalkanoate (PHA) production serves as a substitute for petroleum-based plastics. Enriching mixed microbial cultures (MMCs) with the capacity to store PHA is a key precursor for low-cost PHA production. This study investigated the impact of carbon types on enrichment outcomes. Three MMCs were separately fed by acetate sodium, glucose, and starch as an enriching carbon source, and were exposed to long-term aerobic dynamic feeding (ADF) periods. The PHA production capacity, kinetics and stoichiometry of the enrichments, the PHA composition, and the microbial diversity and community composition were explored to determine carbon and enrichment correlations. After 350-cycle enriching periods under feast-famine (F-F) regimes, the MMCs enriched by acetate sodium and glucose contained a maximum PHA content of 64.7% and 60.5% cell dry weight (CDW). The starch-enriched MMC only had 27.3% CDW of PHA. High-throughput sequencing revealed that non-PHA bacteria survived alongside PHA storing bacteria, even under severe F-F selective pressure. Genus of Pseudomonas and Stappia were the possible PHA accumulating bacteria in acetate-enriched MMC. Genus of Oceanicella, Piscicoccus and Vibrio were found as PHA accumulating bacteria in glucose-enriched MMC. Vibrio genus was the only PHA accumulating bacteria in starch-enriched MMC. The community diversity and composition were regulated by the substrate types. PMID:27485896

  9. Effects of carbon sources on the enrichment of halophilic polyhydroxyalkanoate-storing mixed microbial culture in an aerobic dynamic feeding process

    NASA Astrophysics Data System (ADS)

    Cui, You-Wei; Zhang, Hong-Yu; Lu, Peng-Fei; Peng, Yong-Zhen

    2016-08-01

    Microbial polyhydroxyalkanoate (PHA) production serves as a substitute for petroleum-based plastics. Enriching mixed microbial cultures (MMCs) with the capacity to store PHA is a key precursor for low-cost PHA production. This study investigated the impact of carbon types on enrichment outcomes. Three MMCs were separately fed by acetate sodium, glucose, and starch as an enriching carbon source, and were exposed to long-term aerobic dynamic feeding (ADF) periods. The PHA production capacity, kinetics and stoichiometry of the enrichments, the PHA composition, and the microbial diversity and community composition were explored to determine carbon and enrichment correlations. After 350-cycle enriching periods under feast-famine (F-F) regimes, the MMCs enriched by acetate sodium and glucose contained a maximum PHA content of 64.7% and 60.5% cell dry weight (CDW). The starch-enriched MMC only had 27.3% CDW of PHA. High-throughput sequencing revealed that non-PHA bacteria survived alongside PHA storing bacteria, even under severe F-F selective pressure. Genus of Pseudomonas and Stappia were the possible PHA accumulating bacteria in acetate-enriched MMC. Genus of Oceanicella, Piscicoccus and Vibrio were found as PHA accumulating bacteria in glucose-enriched MMC. Vibrio genus was the only PHA accumulating bacteria in starch-enriched MMC. The community diversity and composition were regulated by the substrate types.

  10. Ecotoxicity effects triggered in aquatic organisms by invasive Acer negundo and native Alnus glutinosa leaf leachates obtained in the process of aerobic decomposition.

    PubMed

    Manusadžianas, Levonas; Darginavičienė, Jūratė; Gylytė, Brigita; Jurkonienė, Sigita; Krevš, Alina; Kučinskienė, Alė; Mačkinaitė, Rimutė; Pakalnis, Romas; Sadauskas, Kazys; Sendžikaitė, Jūratė; Vitkus, Rimantas

    2014-10-15

    The replacement of autochthonous tree species by invasive ones in coastal zones of freshwater bodies induces additional alteration of hydrochemical and microbiological characteristics due to decomposition of fallen leaves of non-indigenous species, which can lead to ecotoxic response of the littoral biota. Leaves of invasive to Lithuania boxelder maple (Acer negundo) and autochthonous black alder (Alnus glutinosa) lost more than half of biomass and released stable amount of DOC (60-70 mg/L) throughout 90-day mesocosm experiment under aerobic conditions. This, along with the relatively small BOD7 values detected after some variation within the first month confirms effective biodegradation by fungi and bacteria. The ambient water was more enriched with different forms of N and P by decomposing boxelder maple than by alder leaves. During the first month, both leachates were more toxic to charophyte (Nitellopsis obtusa) at mortality and membrane depolarization levels, while later to two crustacean species. Biomarker response, H(+)-ATPase activity in membrane preparations from N. obtusa, was stronger for A. negundo. Generally, boxelder maple leaf leachates were more toxic to tested hydrobionts and this coincides with previous study on leaves of the same pair of tree species conducted under microaerobic conditions (Krevš et al., 2013).

  11. Aerobic granules: microbial landscape and architecture, stages, and practical implications.

    PubMed

    Gonzalez-Gil, Graciela; Holliger, Christof

    2014-06-01

    For the successful application of aerobic granules in wastewater treatment, granules containing an appropriate microbial assembly able to remove contaminants should be retained and propagated within the reactor. To manipulate and/or optimize this process, a good understanding of the formation and dynamic architecture of the granules is desirable. Models of granules often assume a spherical shape with an outer layer and an inner core, but limited information is available regarding the extent of deviations from such assumptions. We report on new imaging approaches to gain detailed insights into the structural characteristics of aerobic granules. Our approach stained all components of the granule to obtain a high quality contrast in the images; hence limitations due to thresholding in the image analysis were overcome. A three-dimensional reconstruction of the granular structure was obtained that revealed the mesoscopic impression of the cavernlike interior of the structure, showing channels and dead-end paths in detail. In "old" granules, large cavities allowed for the irrigation and growth of dense microbial colonies along the path of the channels. Hence, in some areas, paradoxically higher biomass content was observed in the inner part of the granule compared to the outer part. Microbial clusters "rooting" from the interior of the mature granule structure indicate that granules mainly grow via biomass outgrowth and not by aggregation of small particles. We identify and discuss phenomena contributing to the life cycle of aerobic granules. With our approach, volumetric tetrahedral grids are generated that may be used to validate complex models of granule formation.

  12. Aerobic Granules: Microbial Landscape and Architecture, Stages, and Practical Implications

    PubMed Central

    Holliger, Christof

    2014-01-01

    For the successful application of aerobic granules in wastewater treatment, granules containing an appropriate microbial assembly able to remove contaminants should be retained and propagated within the reactor. To manipulate and/or optimize this process, a good understanding of the formation and dynamic architecture of the granules is desirable. Models of granules often assume a spherical shape with an outer layer and an inner core, but limited information is available regarding the extent of deviations from such assumptions. We report on new imaging approaches to gain detailed insights into the structural characteristics of aerobic granules. Our approach stained all components of the granule to obtain a high quality contrast in the images; hence limitations due to thresholding in the image analysis were overcome. A three-dimensional reconstruction of the granular structure was obtained that revealed the mesoscopic impression of the cavernlike interior of the structure, showing channels and dead-end paths in detail. In “old” granules, large cavities allowed for the irrigation and growth of dense microbial colonies along the path of the channels. Hence, in some areas, paradoxically higher biomass content was observed in the inner part of the granule compared to the outer part. Microbial clusters “rooting” from the interior of the mature granule structure indicate that granules mainly grow via biomass outgrowth and not by aggregation of small particles. We identify and discuss phenomena contributing to the life cycle of aerobic granules. With our approach, volumetric tetrahedral grids are generated that may be used to validate complex models of granule formation. PMID:24657859

  13. Evaluation of the detoxication efficiencies for acrylonitrile wastewater treated by a combined anaerobic oxic-aerobic biological fluidized tank (A/O-ABFT) process: Acute toxicity and zebrafish embryo toxicity.

    PubMed

    Na, Chunhong; Zhang, Ying; Deng, Minjie; Quan, Xie; Chen, Shuo; Zhang, Yaobin

    2016-07-01

    Acrylonitrile (ACN) wastewater generated during ACN production has been reported to be toxic to many aquatic organisms. However, few studies have evaluated toxicity removal of ACN wastewater during and after the treatment process. In this study, the detoxication ability of an ACN wastewater treatment plant (WWTP) was evaluated using Daphnia magna, Danio rerio and zebrafish embryo. This ACN WWTP has a combined anaerobic oxic-aerobic biological fluidized tank (A/O-ABFT) process upgraded from the traditional anaerobic oxic (A/O) process. Moreover, the potential toxicants of the ACN wastewaters were identified by gas chromatography-mass spectrometry (GC-MS). The raw ACN wastewater showed high acute and embryo toxicity. 3-Cyanopyridine, succinonitrile and a series of nitriles were detected as the toxic contributors of ACN wastewater. The A/O process was effective for the acute and embryo toxicity removal, as well as the organic toxicants. However, the A/O effluent still showed acute and embryo toxicity which was attributed by the undegraded and the newly generated toxicants during the A/O process. The residual acute and embryo toxicity as well as the organic toxicants in the A/O effluent were further reduced after going through the downstream ABFT process system. The final effluent displayed no significant acute and embryo toxicity, and less organic toxicants were detected in the final effluent. The upgrade of this ACN WWTP results in the improved removal efficiencies for acute and embryo toxicity, as well as the organic toxicants.

  14. Removal of Pesticides and Inorganic Contaminants in Anaerobic and Aerobic Biological Contactors

    EPA Science Inventory

    This presentation contains data on the removal of pesticides (acetochlor, clethodim, dicrotophos), ammonia, nitrate, bromate and perchlorate through aerobic and anaerobic biological treatment processes.

  15. The Lomagundi Event Marks Post-Pasteur Point Evolution of Aerobic Respiration: A Hypothesis

    NASA Astrophysics Data System (ADS)

    Raub, T. D.; Kirschvink, J. L.; Nash, C. Z.; Raub, T. M.; Kopp, R. E.; Hilburn, I. A.

    2009-05-01

    All published early Earth carbon cycle models assume that aerobic respiration is as ancient as oxygenic photosynthesis. However, aerobic respiration shuts down at oxygen concentrations below the Pasteur Point, (.01 of the present atmospheric level, PAL). As geochemical processes are unable to produce even local oxygen concentrations above .001 PAL, it follows that aerobic respiration could only have evolved after oxygenic photosynthesis, implying a time gap. The evolution of oxygen reductase-utilizing metabolisms presumably would have occupied this interval. During this time the PS-II-generated free oxygen would have been largely unavailable for remineralization of dissolved organic carbon and so would have profoundly shifted the burial ratio of organic/inorganic carbon. We argue that the sequential geological record of the Makganyene (Snowball?) glaciation (2.3-2.22), the exessively aerobic Hekpoort and coeval paleosols, the Lomagundi-Jatuli carbon isotopic excursion (ending 2.056 Ga), and the deposition of concentrated, sedimentary organic carbon (shungite) mark this period of a profoundly unbalanced global carbon cycle. The Kopp et al. (2005) model for oxyatmoversion agrees with phylogenetic evidence for the radiation of cyanobacteria followed closely by the radiation of gram-negative lineages containing magnetotactic bacteria, which depend upon vertical oxygen gradients. These organisms include delta-Proteobacteria from which the mitochondrial ancestor originated. The Precambrian carbon cycle was rebalanced after a series of biological innovations allowed utilization of the high redox potential of free oxygen. Aerobic respiration in mitochondria required the evolution of a unique family of Fe-Cu oxidases, one of many factors contributing to the >210 Myr delay between the Makganyene deglaciation and the end of the Lomagundi-Jatuli event. We speculate that metalliferious fluids associated with the eruption of the Bushveld complex facilitated evolution of these

  16. An Effective Methodology for Processing and Analyzing Large, Complex Spacecraft Data Streams

    ERIC Educational Resources Information Center

    Teymourlouei, Haydar

    2013-01-01

    The emerging large datasets have made efficient data processing a much more difficult task for the traditional methodologies. Invariably, datasets continue to increase rapidly in size with time. The purpose of this research is to give an overview of some of the tools and techniques that can be utilized to manage and analyze large datasets. We…

  17. 7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Seed in bulk or large quantities; seed for cleaning or... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Labeling in General § 201.33 Seed in bulk or large quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required...

  18. The ATAMM procedure model for concurrent processing of large grained control and signal processing algorithms

    NASA Technical Reports Server (NTRS)

    Stoughton, John W.; Mielke, Roland R.

    1988-01-01

    An overview is presented of a model for describing data and control flow associated with the execution of large-grained, decision-free algorithms in a special distributed computer environment. The ATAMM (Algorithm-To-Architecture Mapping Model) model provides a basis for relating an algorithm to its execution in a dataflow multicomputer environment. The ATAMM model features a marked graph Petri net description of the algorithm behavior with regard to both data and control flow. The model provides an analytical basis for calculating performance bounds on throughput characteristics which are demonstrated here.

  19. Aerobic Exercise Preserves Olfaction Function in Individuals with Parkinson's Disease

    PubMed Central

    Rosenfeldt, Anson B.; Dey, Tanujit

    2016-01-01

    Introduction. Based on anecdotal reports of improved olfaction following aerobic exercise, the aim of this study was to evaluate the effects of an 8-week aerobic exercise program on olfaction function in individuals with Parkinson's disease (PD). Methods. Thirty-eight participants with idiopathic PD were randomized to either an aerobic exercise group (n = 23) or a nonexercise control group (n = 15). The aerobic exercise group completed a 60-minute cycling session three times per week for eight weeks while the nonexercise control group received no intervention. All participants completed the University of Pennsylvania Smell Identification Test (UPSIT) at baseline, end of treatment, and a four-week follow up. Results. Change in UPSIT scores between the exercise and nonexercise groups from baseline to EOT (p = 0.01) and from baseline to EOT+4 (p = 0.02) favored the aerobic exercise group. Individuals in the nonexercise group had worsening olfaction function over time, while the exercise group was spared from decline. Discussion. The difference in UPSIT scores suggested that aerobic exercise may be altering central nervous system pathways that regulate the physiologic or cognitive processes controlling olfaction in individuals with PD. While these results provide promising preliminary evidence that exercise may modify the disease process, further systematic evaluation is necessary. PMID:27999706

  20. Extraterrestrial processing and manufacturing of large space systems. Volume 3: Executive summary

    NASA Technical Reports Server (NTRS)

    Miller, R. H.; Smith, D. B. S.

    1979-01-01

    Facilities and equipment are defined for refining processes to commercial grade of lunar material that is delivered to a 'space manufacturing facility' in beneficiated, primary processed quality. The manufacturing facilities and the equipment for producing elements of large space systems from these materials and providing programmatic assessments of the concepts are also defined. In-space production processes of solar cells (by vapor deposition) and arrays, structures and joints, conduits, waveguides, RF equipment radiators, wire cables, converters, and others are described.

  1. Challenges in polyoxometalate-mediated aerobic oxidation catalysis: catalyst development meets reactor design.

    PubMed

    Lechner, Manuel; Güttel, Robert; Streb, Carsten

    2016-11-14

    Selective catalytic oxidation is one of the most widely used chemical processes. Ideally, highly active and selective catalysts are used in combination with molecular oxygen as oxidant, leading to clean, environmentally friendly process conditions. For homogeneous oxidation catalysis, molecular metal oxide anions, so-called polyoxometalates (POMs) are ideal prototypes which combine high reactivity and stability with chemical tunability on the molecular level. Typically, POM-mediated aerobic oxidations are biphasic, using gaseous O2 and liquid reaction mixtures. Therefore, the overall efficiency of the reaction is not only dependent on the chemical components, but requires chemical engineering insight to design reactors with optimized productivity. This Perspective shows that POM-mediated aerobic liquid-phase oxidations are ideal reactions to be carried out in microstructured flow reactors as they enable facile mass and energy transfer, provide large gas-liquid interfaces and can be easily upscaled. Recent advances in POM-mediated aerobic catalytic oxidations are therefore summarized with a focus on technological importance and mechanistic insight. The principles of reactor design are discussed from a chemical engineering point of view with a focus on homogeneous oxidation catalysis using O2 in microfluidic systems. Further, current limitations to catalytic activity are identified and future directions based on combined chemistry and chemical engineering approaches are discussed to show that this approach could lead to sustainable production methods in industrial chemistry based on alternative energy sources and chemical feedstocks.

  2. Modeling of Cloud/Radiation Processes for Large-Scale Clouds and Tropical Anvils

    DTIC Science & Technology

    1994-05-31

    three-dimensional, large-scale cloud model has been developed for the prediction of cloud cover, cloud liquid /ice water content (LWC/IWC), precipitation...specific humidity and temperature. Partial cloudiness is allowed to form when large-scale relative humidity is less than 100%. Both liquid and ice...phases are included in the model. The liquid phase processes consist of evaporation, condensation, autoconversion and precipitation. The ice phase

  3. Study on fine annealing process of the large-aperture K9 glasses

    NASA Astrophysics Data System (ADS)

    Gang, Wang; Bin, Liu Yi; Zheng, Li Li; Hui, Zhang; Lei, Xie; Min, Qiu Fu; Ping, Ma; Yao, Yan Ding

    2016-10-01

    Study on fine annealing process of the large-aperture K9 glasses was carried out in the report. The process parameters of glass placed way, fan speed and design of the cavity for keeping temperature uniformity were attained. By the fine annealing experiment, the stress distribution was improved evidently. The stress changed from Irregular distribution to consistency symmetric distribution and the stress max was reduced. The surface profile accuracy of the large-aperture K9 glasses was controlled steadily during CNC polishing.

  4. Visual analysis of inter-process communication for large-scale parallel computing.

    PubMed

    Muelder, Chris; Gygi, Francois; Ma, Kwan-Liu

    2009-01-01

    In serial computation, program profiling is often helpful for optimization of key sections of code. When moving to parallel computation, not only does the code execution need to be considered but also communication between the different processes which can induce delays that are detrimental to performance. As the number of processes increases, so does the impact of the communication delays on performance. For large-scale parallel applications, it is critical to understand how the communication impacts performance in order to make the code more efficient. There are several tools available for visualizing program execution and communications on parallel systems. These tools generally provide either views which statistically summarize the entire program execution or process-centric views. However, process-centric visualizations do not scale well as the number of processes gets very large. In particular, the most common representation of parallel processes is a Gantt char t with a row for each process. As the number of processes increases, these charts can become difficult to work with and can even exceed screen resolution. We propose a new visualization approach that affords more scalability and then demonstrate it on systems running with up to 16,384 processes.

  5. Aerobic Requirements for Moving Handweights through Various Ranges of Motion While Walking.

    ERIC Educational Resources Information Center

    Auble, Thomas E.; And Others

    1987-01-01

    Comparison of the aerobic metabolic requirements of normal walking with and without 1-, 2-, and 3-pound handweights among nine adult males indicated that walking while moving handweights through large ranges of motion provides a combined upper and lower body aerobic stimulus that is sufficient for endurance training for persons with poor to…

  6. Cost-effectiveness analysis of TOC removal from slaughterhouse wastewater using combined anaerobic-aerobic and UV/H2O2 processes.

    PubMed

    Bustillo-Lecompte, Ciro Fernando; Mehrvar, Mehrab; Quiñones-Bolaños, Edgar

    2014-02-15

    The objective of this study is to evaluate the operating costs of treating slaughterhouse wastewater (SWW) using combined biological and advanced oxidation processes (AOPs). This study compares the performance and the treatment capability of an anaerobic baffled reactor (ABR), an aerated completely mixed activated sludge reactor (AS), and a UV/H2O2 process, as well as their combination for the removal of the total organic carbon (TOC). Overall efficiencies are found to be up to 75.22, 89.47, 94.53, 96.10, 96.36, and 99.98% for the UV/H2O2, ABR, AS, combined AS-ABR, combined ABR-AS, and combined ABR-AS-UV/H2O2 processes, respectively. Due to the consumption of electrical energy and reagents, operating costs are calculated at optimal conditions of each process. A cost-effectiveness analysis (CEA) is performed at optimal conditions for the SWW treatment by optimizing the total electricity cost, H2O2 consumption, and hydraulic retention time (HRT). The combined ABR-AS-UV/H2O2 processes have an optimal TOC removal of 92.46% at an HRT of 41 h, a cost of $1.25/kg of TOC removed, and $11.60/m(3) of treated SWW. This process reaches a maximum TOC removal of 99% in 76.5 h with an estimated cost of $2.19/kg TOC removal and $21.65/m(3) treated SWW, equivalent to $6.79/m(3) day.

  7. Large scale neural circuit mapping data analysis accelerated with the graphical processing unit (GPU)

    PubMed Central

    Shi, Yulin; Veidenbaum, Alexander V.; Nicolau, Alex; Xu, Xiangmin

    2014-01-01

    Background Modern neuroscience research demands computing power. Neural circuit mapping studies such as those using laser scanning photostimulation (LSPS) produce large amounts of data and require intensive computation for post-hoc processing and analysis. New Method Here we report on the design and implementation of a cost-effective desktop computer system for accelerated experimental data processing with recent GPU computing technology. A new version of Matlab software with GPU enabled functions is used to develop programs that run on Nvidia GPUs to harness their parallel computing power. Results We evaluated both the central processing unit (CPU) and GPU-enabled computational performance of our system in benchmark testing and practical applications. The experimental results show that the GPU-CPU co-processing of simulated data and actual LSPS experimental data clearly outperformed the multi-core CPU with up to a 22x speedup, depending on computational tasks. Further, we present a comparison of numerical accuracy between GPU and CPU computation to verify the precision of GPU computation. In addition, we show how GPUs can be effectively adapted to improve the performance of commercial image processing software such as Adobe Photoshop. Comparison with Existing Method(s) To our best knowledge, this is the first demonstration of GPU application in neural circuit mapping and electrophysiology-based data processing. Conclusions Together, GPU enabled computation enhances our ability to process large-scale data sets derived from neural circuit mapping studies, allowing for increased processing speeds while retaining data precision. PMID:25277633

  8. Science: The Salters' Approach--A Case Study of the Process of Large Scale Curriculum Development.

    ERIC Educational Resources Information Center

    Campbell, Bob; And Others

    1994-01-01

    Analyzes the process of large scale curriculum development. Locates the projects and their development within the range of approaches advocated in science education and considers the practical decisions taken during the development in relation to theories of curriculum development and change. (ZWH)

  9. Parents' Perceptions of the Referral Process for Special Education Services in a Large Florida School District

    ERIC Educational Resources Information Center

    Pierre-Okerson, Marie Judith

    2014-01-01

    The purpose of this research study was to explore how parents in a large school district in Florida perceive the referral process leading to their children placement in Special Education. Participants in the study were 12 parents of special needs students whose children were, at the time of the study, receiving Special Education related services…

  10. Synthesis and characterization of large optical grade sapphire windows produced from a horizontal growth process

    NASA Astrophysics Data System (ADS)

    Levine, Jonathan B.; Burks, Timothy; Ciraldo, John; Montgomery, Matthew; Novoselov, Andrey; Podlozhenov, Sergey

    2013-06-01

    As sensor technology and applications have advanced over the years, the size of sensor windows has grown substantially to satisfy current and future demands. Rubicon Technology, with their strong history in scaling sapphire crystal growth and large scale production processes, has successfully produced large sapphire blanks using a highly modified horizontal directional solidification process. Several prototypes have been synthesized up to 1.75 inches thick, 14 inches wide and 20 inches long. Crystal properties and optical characteristics such as transmission and refractive index homogeneity will be presented on several polished bubble-free windows with excellent results. This research sets the standard for high quality monolithic sapphire sheets large enough for use as seamless integrated optical windows in both military and civilian applications.

  11. TRANSIENT ACCIDENT ANALYSIS OF THE GLOVEBOX SYSTEM IN A LARGE PROCESS ROOM

    SciTech Connect

    Lee, S

    2008-01-11

    Local transient hydrogen concentrations were evaluated inside a large process room when the hydrogen gas was released by three postulated accident scenarios associated with the process tank leakage and fire leading to a loss of gas confinement. The three cases considered in this work were fire in a room, loss of confinement from a process tank, and loss of confinement coupled with fire event. Based on these accident scenarios in a large and unventilated process room, the modeling calculations of the hydrogen migration were performed to estimate local transient concentrations of hydrogen due to the sudden leakage and release from a glovebox system associated with the process tank. The modeling domain represented the major features of the process room including the principal release or leakage source of gas storage system. The model was benchmarked against the literature results for key phenomena such as natural convection, turbulent behavior, gas mixing due to jet entrainment, and radiation cooling because these phenomena are closely related to the gas driving mechanisms within a large air space of the process room. The modeling results showed that at the corner of the process room, the gas concentrations migrated by the Case 2 and Case 3 scenarios reached the set-point value of high activity alarm in about 13 seconds, while the Case 1 scenario takes about 90 seconds to reach the concentration. The modeling results were used to estimate transient radioactive gas migrations in an enclosed process room installed with high activity alarm monitor when the postulated leakage scenarios are initiated without room ventilation.

  12. A large-scale interactive one-dimensional array processing system. [for spectrophotometric data

    NASA Technical Reports Server (NTRS)

    Clark, R. N.

    1980-01-01

    The work describes a scientist/user oriented interactive program for processing one-dimensional arrays. It is shown that the program is oriented toward processing spectrophotometric astronomical data and can also be used for general I-D array processing. Further, the program has totally free format input with a sophisticated decoding capability which can cope with typographical plus other possible mistakes. Finally, a description of the program is given to provide information on implementing a large-scale data-reduction facility.

  13. Complete nitrogen removal from municipal wastewater via partial nitrification by appropriately alternating anoxic/aerobic conditions in a continuous plug-flow step feed process.

    PubMed

    Ge, Shijian; Peng, Yongzhen; Qiu, Shuang; Zhu, Ao; Ren, Nanqi

    2014-05-15

    This study assessed the technical feasibility of removing nitrogen from municipal wastewater by partial nitrification (nitritation) in a continuous plug-flow step feed process. Nitrite in the effluent accumulated to over 81.5  ± 9.2% but disappeared with the transition of process operation from anoxic/oxic mode to the anaerobic/anoxic/oxic mode. Batch tests showed obvious ammonia oxidizing bacteria (AOB) stimulation (advanced ammonia oxidation rate) and nitrite (NOB) oxidizing bacteria inhibition (reduced nitrite oxidation rate) under transient anoxic conditions. Two main factors contributed to nitritation in this continuous plug-flow process: One was the alternating anoxic and oxic operational condition; the step feed strategy guaranteed timely denitrification in anoxic zones, allowing a reduction in energy supply (nitrite) to NOB. Fluorescence in Situ Hybridization and quantitative real-time polymerase chain reaction analysis indicated that NOB population gradually decreased to 1.0  ± 0.1% of the total bacterial population (dominant Nitrospira spp., 1.55 × 10(9) copies/L) while AOB increased approximately two-fold (7.4  ± 0.9%, 1.25 × 10(10) copies/L) during the above anoxic to anaerobic transition. Most importantly, without addition of external carbon sources, the above wastewater treatment process reached 86.0  ± 4.2% of total nitrogen (TN) removal with only 7.23 ± 2.31 mg/L of TN in the effluent, which met the discharge requirements.

  14. Alternative Patterning Process for Realization of Large-Area, Full-Color, Active Quantum Dot Display.

    PubMed

    Park, Joon-Suh; Kyhm, Jihoon; Kim, Hong Hee; Jeong, Shinyoung; Kang, JoonHyun; Lee, Song-Ee; Lee, Kyu-Tae; Park, Kisun; Barange, Nilesh; Han, JiYeong; Song, Jin Dong; Choi, Won Kook; Han, Il Ki

    2016-11-09

    Although various colloidal quantum dot (QD) coating and patterning techniques have been developed to meet the demands in optoelectronic applications over the past years, each of the previously demonstrated methods has one or more limitations and trade-offs in forming multicolor, high-resolution, or large-area patterns of QDs. In this study, we present an alternative QD patterning technique using conventional photolithography combined with charge-assisted layer-by-layer (LbL) assembly to solve the trade-offs of the traditional patterning processes. From our demonstrations, we show repeatable QD patterning process that allows multicolor QD patterns in both large-area and microscale. Also, we show that the QD patterns are robust against additional photolithography processes and that the thickness of the QD patterns can be controlled at each position. To validate that this process can be applied to actual device applications as an active material, we have fabricated inverted, differently colored, active QD light-emitting device (QD-LED) on a pixelated substrate, which achieved maximum electroluminescence intensity of 23 770 cd/m(2), and discussed the results. From our findings, we believe that our process provides a solution to achieving both high-resolution and large-scale QD pattern applicable to not only display, but also to practical photonic device research and development.

  15. Structure/property development in aPET during large strain, solid phase polymer processing

    NASA Astrophysics Data System (ADS)

    Martin, Peter; Mohamed, Raja Roslan Raja

    2015-12-01

    Amorphous Polyethylene terephthalate (aPET) is increasingly of interest for the polymer packaging industry due to its blend of excellent mechanical properties and most importantly its ease of recyclability. Among the major commercial polymers it is almost unique in the degree of improvement in mechanical properties that can be obtained through process-induced strain. For many years these unique properties have been very successfully exploited in the injection stretch blow molding process, where it is deliberately stretched to very large strains using extremely high pressures. However, the material is now also being used in much lower pressure processes such as thermoforming where its properties are often not fully exploited. In this work the change in structure and properties of aPET with strain is systematically investigated using a high speed biaxial stretching machine. The aim was to demonstrate how the properties of the material could be controlled by large strain, high temperature biaxial stretching processes such as thermoforming and blow molding. The results show that property changes in the material are driven by orientation and the onset of rapid strain hardening at large strains. This in turn is shown to vary strongly with process-induced parameters such as the strain rate and the mode and magnitude of biaxial deformation.

  16. Lower Current Large Deviations for Zero-Range Processes on a Ring

    NASA Astrophysics Data System (ADS)

    Chleboun, Paul; Grosskinsky, Stefan; Pizzoferrato, Andrea

    2017-04-01

    We study lower large deviations for the current of totally asymmetric zero-range processes on a ring with concave current-density relation. We use an approach by Jensen and Varadhan which has previously been applied to exclusion processes, to realize current fluctuations by travelling wave density profiles corresponding to non-entropic weak solutions of the hyperbolic scaling limit of the process. We further establish a dynamic transition, where large deviations of the current below a certain value are no longer typically attained by non-entropic weak solutions, but by condensed profiles, where a non-zero fraction of all the particles accumulates on a single fixed lattice site. This leads to a general characterization of the rate function, which is illustrated by providing detailed results for four generic examples of jump rates, including constant rates, decreasing rates, unbounded sublinear rates and asymptotically linear rates. Our results on the dynamic transition are supported by numerical simulations using a cloning algorithm.

  17. Lower Current Large Deviations for Zero-Range Processes on a Ring

    NASA Astrophysics Data System (ADS)

    Chleboun, Paul; Grosskinsky, Stefan; Pizzoferrato, Andrea

    2017-02-01

    We study lower large deviations for the current of totally asymmetric zero-range processes on a ring with concave current-density relation. We use an approach by Jensen and Varadhan which has previously been applied to exclusion processes, to realize current fluctuations by travelling wave density profiles corresponding to non-entropic weak solutions of the hyperbolic scaling limit of the process. We further establish a dynamic transition, where large deviations of the current below a certain value are no longer typically attained by non-entropic weak solutions, but by condensed profiles, where a non-zero fraction of all the particles accumulates on a single fixed lattice site. This leads to a general characterization of the rate function, which is illustrated by providing detailed results for four generic examples of jump rates, including constant rates, decreasing rates, unbounded sublinear rates and asymptotically linear rates. Our results on the dynamic transition are supported by numerical simulations using a cloning algorithm.

  18. Influence of thermophilic aerobic digestion as a sludge pre-treatment and solids retention time of mesophilic anaerobic digestion on the methane production, sludge digestion and microbial communities in a sequential digestion process.

    PubMed

    Jang, Hyun Min; Cho, Hyun Uk; Park, Sang Kyu; Ha, Jeong Hyub; Park, Jong Moon

    2014-01-01

    In this study, the changes in sludge reduction, methane production and microbial community structures in a process involving two-stage thermophilic aerobic digestion (TAD) and mesophilic anaerobic digestion (MAD) under different solid retention times (SRTs) between 10 and 40 days were investigated. The TAD reactor (RTAD) was operated with a 1-day SRT and the MAD reactor (RMAD) was operated at three different SRTs: 39, 19 and 9 days. For a comparison, control MAD (RCONTROL) was operated at three different SRTs of 40, 20 and 10 days. Our results reveal that the sequential TAD-MAD process has about 42% higher methane production rate (MPR) and 15% higher TCOD removal than those of RCONTROL when the SRT decreased from 40 to 20 days. Denaturing gradient gel electrophoresis (DGGE) and real-time PCR results indicate that RMAD maintained a more diverse bacteria and archaea population compared to RCONTROL, due to the application of the biological TAD pre-treatment process. In RTAD, Ureibacillus thermophiles and Bacterium thermus were the major contributors to the increase in soluble organic matter. In contrast, Methanosaeta concilii, a strictly aceticlastic methanogen, showed the highest population during the operation of overall SRTs in RMAD. Interestingly, as the SRT decreased to 20 days, syntrophic VFA oxidizing bacteria, Clostridium ultunense sp., and a hydrogenotrophic methanogen, Methanobacterium beijingense were detected in RMAD and RCONTROL. Meanwhile, the proportion of archaea to total microbe in RMAD and RCONTROL shows highest values of 10.5 and 6.5% at 20-d SRT operation, respectively. Collectively, these results demonstrate that the increased COD removal and methane production at different SRTs in RMAD might be attributed to the increased synergism among microbial species by improving the hydrolysis of the rate limiting step in sludge with the help of the biological TAD pre-treatment.

  19. Die aerobe Glykolyse der Tumorzelle

    NASA Astrophysics Data System (ADS)

    Schneider, Friedhelm

    1981-01-01

    A high aerobic glycolysis (aerobic lactate production) is the most significant feature of the energy metabolism of rapidly growing tumor cells. Several mechanisms, which may be different in different cell lines, seem to be involved in this characteristic of energy metabolism of the tumor cell. Changes in the cell membrane leading to increased uptake and utilization of glucose, a high level of fetal types of isoenzymes, a decreased number of mitochondria and a reduced capacity to metabolize pyruvate are some factors which must be taken into consideration. It is not possible to favour one of them at the present time.

  20. Advanced treatment of landfill leachate using anaerobic-aerobic process: organic removal by simultaneous denitritation and methanogenesis and nitrogen removal via nitrite.

    PubMed

    Sun, Hongwei; Peng, Yongzhen; Shi, Xiaoning

    2015-02-01

    A novel biological system coupling an UASB and a SBR was established to treat landfill leachate. In order to enhance organics and nitrogen removal, simultaneous denitritation and methanogenesis (SDM) was performed in the UASB. Free ammonia (FA) inhibition on nitrite-oxidizing bacteria (NOB) and process control was used to achieve nitrite pathway in the SBR. Results over 623 days showed that the maximum organic removal rate in the UASB and the maximum ammonium oxidization rate in the SBR was 12.7 kgCOD/m(3) d and 0.96 kgN/m(3) d, respectively. The system achieved COD, TN, and NH4(+)-N removal efficiencies of 93.5%, 99.5%, and 99.1%, respectively. By using FA inhibition coupled with process control, the nitrite pathway was started-up in the SBR at low temperatures (14.0-18.2°C) and was maintained for 142 days at temperatures below 15°C (the lowest level was 9.0°C). The predominant ammonia-oxidizing bacteria (AOB) explains essentially stable nitritation obtained.

  1. Occurrence and removal of six pharmaceuticals and personal care products in a wastewater treatment plant employing anaerobic/anoxic/aerobic and UV processes in Shanghai, China.

    PubMed

    Wang, Dan; Sui, Qian; Lu, Shu-Guang; Zhao, Wen-Tao; Qiu, Zhao-Fu; Miao, Zhou-Wei; Yu, Gang

    2014-03-01

    The occurrence and removal of six pharmaceuticals and personal care products (PPCPs) including caffeine (CF), N, N-diethyl-meta-toluamide (DEET), carbamazepine, metoprolol, trimethoprim (TMP), and sulpiride in a municipal wastewater treatment plant (WWTP) in Shanghai, China were studied in January 2013; besides, grab samples of the influent were also taken every 6 h, to investigate the daily fluctuation of the wastewater influent. The results showed the concentrations of the investigated PPCPs ranged from 17 to 11,400 ng/L in the WWTP. A low variability of the PPCP concentrations in the wastewater influent throughout the day was observed, with the relative standard deviations less than 25 % for most samples. However, for TMP and CF, the slight daily fluctuation still reflected their consumption patterns. All the target compounds except CF and DEET, exhibited poor removal efficiencies (<40 %) by biological treatment process, probably due to the low temperature in the bioreactor, which was unfavorable for activated sludge. While for the two biodegradable PPCPs, CF, and DEET, the anaerobic and oxic tank made contributions to their removal while the anoxic tank had a negative effect to their elimination. The tertiary UV treatment removed the investigated PPCPs by 5-38 %, representing a crucial polishing step to compensate for the poor removal by the biologic treatment process in winter.

  2. Distributed model of hydrological and sediment transport processes in large river basins in Southeast Asia

    NASA Astrophysics Data System (ADS)

    Zuliziana, S.; Tanuma, K.; Yoshimura, C.; Saavedra, O. C.

    2015-07-01

    Soil erosion and sediment transport have been modeled at several spatial and temporal scales, yet few models have been reported for large river basins (e.g., drainage areas > 100 000 km2). In this study, we propose a process-based distributed model for assessment of sediment transport at a large basin scale. A distributed hydrological model was coupled with a process-based distributed sediment transport model describing soil erosion and sedimentary processes at hillslope units and channels. The model was tested on two large river basins: the Chao Phraya River Basin (drainage area: 160 000 km2) and the Mekong River Basin (795 000 km2). The simulation over 10 years showed good agreement with the observed suspended sediment load in both basins. The average Nash-Sutcliffe efficiency (NSE) and average correlation coefficient (r) between the simulated and observed suspended sediment loads were 0.62 and 0.61, respectively, in the Chao Phraya River Basin except the lowland section. In the Mekong River Basin, the overall average NSE and r were 0.60 and 0.78, respectively. Sensitivity analysis indicated that suspended sediment load is sensitive to detachability by raindrop (k) in the Chao Phraya River Basin and to soil detachability over land (Kf) in the Mekong River Basin. Overall, the results suggest that the present model can be used to understand and simulate erosion and sediment transport in large river basins.

  3. Finite-time parametric identification for the model representing the metabolic and genetic regulatory effects of sequential aerobic respiration and anaerobic fermentation processes in Escherichia coli.

    PubMed

    Sepúlveda-Gálvez, Alfonso; Agustín Badillo-Corona, Jesús; Chairez, Isaac

    2017-03-17

    Mathematical modelling applied to biological systems allows for the inferring of changes in the dynamic behaviour of organisms associated with variations in the environment. Models based on ordinary differential equations are most commonly used because of their ability to describe the mechanisms of biological systems such as transcription. The disadvantage of using this approach is that there is a large number of parameters involved and that it is difficult to obtain them experimentally. This study presents an algorithm to obtain a finite-time parameter characterization of the model used to describe changes in the metabolic behaviour of Escherichia coli associated with environmental changes. In this scheme, super-twisting algorithm was proposed to recover the derivative of all the proteins and mRNA of E. coli associated to changes in the concentration of oxygen available in the growth media. The 75 identified parameters in this study maintain the biological coherence of the system and they were estimated with no more than 20% error with respect to the real ones included in the proposed model.

  4. Multi-stage evolution process of large scale landslides at the Patanpunas stream, Taiwan

    NASA Astrophysics Data System (ADS)

    Lin, Ming-Lang; Lee, Kuo-Chen; Lo, Chia-Ming; Weng, Meng-Chia; Lee, Shun-Min

    2016-04-01

    This study used multi-temporal terrain and remote sensing images to investigate the geomorphological evolution of the Putanpunas stream caused by large-scale landslides over the last decade. We conducted an analysis of the landslides evolution process within the study area, which included a multi-temporal terrain analysis, remote sensing interpretation, surface displacement analysis, and mechanism investigation. By integrating the results from these analyses, we provided explanations for the topographic and geomorphologic action processes of the deep-seated landslides as well as the development of the potential collapsing mechanisms within the study area. Then, discrete element method was used to simulate the process of landslide movement and deposition. The results show that the evolution process of large-scale landslides in the Putanpunas stream can be divided into four stages, namely downcutting of the stream gully and decompression of the river gully in the early stage, creep and deformation of the rock slope, sliding surface development of the deformed bands in the rock strata, and movement of the sliding mass. The results of terrain analysis and interpretation show topographical changes in the alluvial fan downstream and the deposits in the midstream and downstream segments of the Putanpunas Stream between 2005 and 2009. In 2009, torrential rainfall induced large-scale landslides that greatly altered the terrain of the Putanpunas Stream and the alluvial fan. There still exists 7.2 × 107 m3 of unstable colluvium accumulated at the slope surface and stream gully within the upstream and midstream areas. In 2012, further large-scale landslides turned the colluvial layer into debris flows that cut across the Ryukyu Terraces downstream to the downstream segment of the Laonong Stream to the southwest. This greatly changed later debris flows and alluvial fan deposits. Key Words: large-scale landslides, multi-temporal terrain, remote sensing, discrete element method

  5. The Transition from Aerobic to Anaerobic Metabolism.

    ERIC Educational Resources Information Center

    Skinner, James S.; McLellan, Thomas H.

    1980-01-01

    The transition from aerobic to anaerobic metabolism is discussed. More research is needed on different kinds of athletes and athletic activities and how they may affect aerobic and anaerobic metabolisms. (CJ)

  6. Bacteria associated with processed crawfish and potential toxin production by Clostridium botulinum type E in vacuum-packaged and aerobically packaged crawfish tails.

    PubMed

    Lyon, W J; Reddmann, C S

    2000-12-01

    Refrigerated vacuum-packaged storage has been shown to increase significantly the shelf life of fresh fish and seafood products, but the effect, if any, on the outgrowth and toxin production of Clostridium botulinum type E on cooked crawfish is unknown. Microflora associated with live crawfish reflect the microbial populations of the harvest water and sediments in which they are living. The presence or absence of specific pathogens in either vacuum-packaged or air-permeable bags of cooked crawfish have not been thoroughly evaluated. This study evaluates the potential survival and outgrowth of biological hazards in both vacuum-packaged and air-permeable-packaged cooked crawfish held at 4 and 10 degrees C for 30 days. During shelf-life studies of vacuum-packaged and air-permeable-bagged cooked crawfish, a total of 31 bacterial species were isolated and identified from crawfish samples using both selective and nonselective media. The only pathogens isolated from both vacuum-packed and air-permeable bags of processed crawfish samples during shelf-life studies were strains of Aeromonas hydrophila and Staphylococcus aureus. C. botulinum type E and Clostridium perfringens species were not isolated from any of the uninoculated crawfish samples. Cooked crawfish were inoculated with 10(3) C. botulinum type E spores per g of crawfish tail meat to determine whether cooked crawfish tails would support the growth of C. botulinum type E strains and produce toxin at refrigerated temperatures. Spore-inoculated crawfish tails were vacuum packaged in both a high barrier film and an air-permeable bag and stored at 4 degrees C and 10 degrees C for 30 days. C. botulinum toxin E was not detected in any of the spore-inoculated packages throughout the shelf-life study until day 30. Microbiological data from this study should be useful in the development and implementation of the hazard analysis and critical control point plans for processed crawfish tails.

  7. Efficient development and processing of thermal math models of very large space truss structures

    NASA Technical Reports Server (NTRS)

    Warren, Andrew H.; Arelt, Joseph E.; Lalicata, Anthony L.

    1993-01-01

    As the spacecraft moves along the orbit, the truss members are subjected to direct and reflected solar, albedo and planetary infra-red (IR) heating rates, as well as IR heating and shadowing from other spacecraft components. This is a transient process with continuously changing heating loads and the shadowing effects. The resulting nonuniform temperature distribution may cause nonuniform thermal expansion, deflection and stress in the truss elements, truss warping and thermal distortions. There are three challenges in the thermal-structural analysis of the large truss structures. The first is the development of the thermal and structural math models, the second - model processing, and the third - the data transfer between the models. All three tasks require considerable time and computer resources to be done because of a very large number of components involved. To address these challenges a series of techniques of automated thermal math modeling and efficient processing of very large space truss structures were developed. In the process the finite element and finite difference methods are interfaced. A very substantial reduction of the quantity of computations was achieved while assuring a desired accuracy of the results. The techniques are illustrated on the thermal analysis of a segment of the Space Station main truss.

  8. Haemoglobin, blood volume, cardiac function, and aerobic power.

    PubMed

    Gledhill, N; Warburton, D; Jamnik, V

    1999-02-01

    Alterations in [Hb], which are mediated through changes in arterial oxygen content, and alterations in BV, which are mediated through changes in cardiac output (Q), have a significant effect on both VO2max and aerobic performance. If BV is held constant, a decrease in [Hb] (anaemia) causes a decrease in VO2max and aerobic performance, while an increase in [Hb] (blood doping) causes an increase in VO2max and aerobic performance. If [Hb] is held constant, an increase in BV can cause and increase in both VO2max and aerobic performance, while a decrease in BV can cause a decrease in VO2max and aerobic performance. In addition, an increase in BV can compensate for moderate reductions in [Hb] through increase in Q, allowing VO2max to remain unchanged or even increase. Also, a large portion of the difference in the enhanced cardiovascular function of endurance athletes is due to their high BV and the resultant enhancement of diastolic function. Hence, optimizing both [Hb] and BV is a very important consideration for endurance performance.

  9. Moditored unsaturated soil transport processes as a support for large scale soil and water management

    NASA Astrophysics Data System (ADS)

    Vanclooster, Marnik

    2010-05-01

    The current societal demand for sustainable soil and water management is very large. The drivers of global and climate change exert many pressures on the soil and water ecosystems, endangering appropriate ecosystem functioning. The unsaturated soil transport processes play a key role in soil-water system functioning as it controls the fluxes of water and nutrients from the soil to plants (the pedo-biosphere link), the infiltration flux of precipitated water to groundwater and the evaporative flux, and hence the feed back from the soil to the climate system. Yet, unsaturated soil transport processes are difficult to quantify since they are affected by huge variability of the governing properties at different space-time scales and the intrinsic non-linearity of the transport processes. The incompatibility of the scales between the scale at which processes reasonably can be characterized, the scale at which the theoretical process correctly can be described and the scale at which the soil and water system need to be managed, calls for further development of scaling procedures in unsaturated zone science. It also calls for a better integration of theoretical and modelling approaches to elucidate transport processes at the appropriate scales, compatible with the sustainable soil and water management objective. Moditoring science, i.e the interdisciplinary research domain where modelling and monitoring science are linked, is currently evolving significantly in the unsaturated zone hydrology area. In this presentation, a review of current moditoring strategies/techniques will be given and illustrated for solving large scale soil and water management problems. This will also allow identifying research needs in the interdisciplinary domain of modelling and monitoring and to improve the integration of unsaturated zone science in solving soil and water management issues. A focus will be given on examples of large scale soil and water management problems in Europe.

  10. Arthritis and Aerobic Exercise: A Review.

    ERIC Educational Resources Information Center

    Ike, Robert W.; And Others

    1989-01-01

    Arthritic patients who regularly do aerobic exercise make significant gains in aerobic and functional status, and in subjective areas like pain tolerance and mood. Still, they are often advised to curtail physical activity. Guidelines are presented for physicians prescribing aerobic exercise. An exercise tolerance test is recommended. (SM)

  11. A mesh density study for application to large deformation rolling process evaluations

    SciTech Connect

    Martin, J.A.

    1997-12-01

    When addressing large deformation through an elastic-plastic analysis the mesh density is paramount in determining the accuracy of the solution. However, given the nonlinear nature of the problem, a highly-refined mesh will generally require a prohibitive amount of computer resources. This paper addresses finite element mesh optimization studies considering accuracy of results and computer resource needs as applied to large deformation rolling processes. In particular, the simulation of the thread rolling manufacturing process is considered using the MARC software package and a Cray C90 supercomputer. Both mesh density and adaptive meshing on final results for both indentation of a rigid body to a specified depth and contact rolling along a predetermined length are evaluated.

  12. Theory of large-scale HF heating processes in the unstructured and structured ionosphere

    SciTech Connect

    Keskinen, M.J.; Chaturvedi, P.K.; Ossakow, S.L.

    1990-10-01

    Theoretical aspects of large-scale HF heating processes in the unstructured and structured ionosphere have been studied. For the unstructured case, we present an analytical model for the generation, convection, and steepening of HF-induced density cavities. We discuss the nonlinear propagation of high power HF in steepened cavities. Properties of thermal self-focusing instabilities in the presence of a convecting and steepened cavity is studied. For the structured ionosphere, we discuss parametric coupling processes of a large amplitude HF pump wave with both F-region, i.e., interchange, current-convective, and ion cyclotron and E-region, i.e., two-stream and gradient-drift ionospheric instabilities which instabilities have been proposed to account, in part, for naturally occurring ionospheric irregularities. We show that these instabilities may be stabilized or destabilized using high power HF heaters.

  13. Load Shedding Scheme in Large Pulp Mill by Using Analytic Hierarchy Process

    NASA Astrophysics Data System (ADS)

    Goh, H. H.; Kok, B. C.; Lee, S. W.; Zin, A. A. Mohd.

    2011-06-01

    Pulp mill is one of the heavy industries that consumes large amount of electricity in its production. In particular, the breakdown of the generator would cause other generators to be overloaded. Thus, load shedding scheme is the best way in handling such condition. Selected load will be shed under this scheme in order to protect the generators from being damaged. In the meantime, the subsequence loads will be shed until the generators are sufficient to provide the power to other loads. In order to determine the sequences of load shedding scheme, analytic hierarchy process (AHP) is introduced. Analytic Hierarchy Process is one of the multi-criteria decision making methods. By using this method, the priority of the load can be determined. This paper presents the theory of the alternative methods to choose the load priority in load shedding scheme for a large pulp mill.

  14. Evaluating and Grading Students in Large-Scale Image Processing Courses.

    PubMed

    Artner, Nicole M; Janusch, Ines; Kropatsch, Walter G

    2015-01-01

    In undergraduate practical courses, it is common to work with groups of 100 or more students. These large-scale courses bring their own challenges. For example, course problems are too small and lack "the big picture"; grading becomes burdensome and repetitive for the teaching staff; and it is difficult to detect cheating. Based on their experience with a traditional large-scale practical course in image processing, the authors developed a novel course approach to teaching "Introduction to Digital Image Processing" (or EDBV, from the German course title Einführung in die Digitale Bild-Verarbeitung) for all undergraduate students of media informatics and visual computing and medical informatics at the TU Wien.

  15. Process virtualization of large-scale lidar data in a cloud computing environment

    NASA Astrophysics Data System (ADS)

    Guan, Haiyan; Li, Jonathan; Zhong, Liang; Yongtao, Yu; Chapman, Michael

    2013-10-01

    Light detection and ranging (lidar) technologies have proven to be the most powerful tools to collect, within a short time, three-dimensional (3-D) point clouds with high-density, high-accuracy and significantly detailed surface information pertaining to terrain and objects. However, in terms of feature extraction and 3-D reconstruction in a computer-aided drawing (CAD) format, most of the existing stand-alone lidar data processing software packages are unable to process a large volume of lidar data in an effective and efficient fashion. To break this technical bottleneck, through the design of a Condor-based process virtualization platform, we presented in this paper a novel strategy that uses network-related computational resources to process, manage, and distribute vast quantities of lidar data in a cloud computing environment. Three extensive experiments with and without a cloud computing environment were compared. The experiment results demonstrated that the proposed process virtualization approach is promisingly applicable and effective in the management of large-scale lidar point clouds.

  16. Microarray Data Processing Techniques for Genome-Scale Network Inference from Large Public Repositories.

    PubMed

    Chockalingam, Sriram; Aluru, Maneesha; Aluru, Srinivas

    2016-09-19

    Pre-processing of microarray data is a well-studied problem. Furthermore, all popular platforms come with their own recommended best practices for differential analysis of genes. However, for genome-scale network inference using microarray data collected from large public repositories, these methods filter out a considerable number of genes. This is primarily due to the effects of aggregating a diverse array of experiments with different technical and biological scenarios. Here we introduce a pre-processing pipeline suitable for inferring genome-scale gene networks from large microarray datasets. We show that partitioning of the available microarray datasets according to biological relevance into tissue- and process-specific categories significantly extends the limits of downstream network construction. We demonstrate the effectiveness of our pre-processing pipeline by inferring genome-scale networks for the model plant Arabidopsis thaliana using two different construction methods and a collection of 11,760 Affymetrix ATH1 microarray chips. Our pre-processing pipeline and the datasets used in this paper are made available at http://alurulab.cc.gatech.edu/microarray-pp.

  17. Large volume leukapheresis: Efficacy and safety of processing patient's total blood volume six times.

    PubMed

    Bojanic, Ines; Dubravcic, Klara; Batinic, Drago; Cepulic, Branka Golubic; Mazic, Sanja; Hren, Darko; Nemet, Damir; Labar, Boris

    2011-04-01

    Large-volume leukapheresis (LVL) differs from standard leukapheresis by increased blood flow and an altered anticoagulation regimen. An open issue is to what degree a further increase in processed blood volume is reasonable in terms of higher yields and safety. In 30 LVL performed in patients with hematologic malignancies, 6 total blood volumes were processed. LVL resulted in a higher CD34+ cell yield without a change in graft quality. Although a marked platelet decrease can be expected, LVL is safe and can be recommended as the standard procedure for patients who mobilize low numbers of CD34+ cells and when high number of CD34+ cells are required.

  18. Large-scale data-flow computer for parallel signal processing

    SciTech Connect

    Wong, F.S.; Ito, M.R.

    1982-01-01

    The authors describe a proposed data-driven, parallel computing machine for signal processing applications in which program codes are often executed repeatedly. This dataflow computer (DFC) consists of a large number of processing modules (PM) operating asynchronously; multiple concurrent activations of a single procedure could be supported by each PM without replication of codes. The architectural design emphasizes simplicity of system operations, modularity, speed and feasibility with current technology. Performance studies are carried out via software simulations. Results show some insights to the basic organization and the various modes of computation, the speed-ups and robustness of the design are also tested with the variations of several system parameters. 4 references.

  19. Research on the mechanism of multiple inductively coupled plasma source for large area processing

    NASA Astrophysics Data System (ADS)

    Lee, Jangjae; Kim, Sijun; Kim, Daewoong; Kim, Kwangki; Lee, Youngseok; You, Shinjae

    2016-09-01

    In the plasma processing, inductively coupled plasma having the high-density is often used for high productivity. In large area plasma processing, the plasma can be generated by using the multi-pole connected in parallel. However, in case of this, it is difficult for power to be transferred to plasma uniformly. To solve the problem, we studied the mechanism of inductively coupled plasma connected in parallel. By using the transformer model, the multiple ICP source is treated. We also studied about the change of the plasma parameters over the time through the power balance equation and particle balance equation. Corresponding author.

  20. Curbing variations in packaging process through Six Sigma way in a large-scale food-processing industry

    NASA Astrophysics Data System (ADS)

    Desai, Darshak A.; Kotadiya, Parth; Makwana, Nikheel; Patel, Sonalinkumar

    2015-08-01

    Indian industries need overall operational excellence for sustainable profitability and growth in the present age of global competitiveness. Among different quality and productivity improvement techniques, Six Sigma has emerged as one of the most effective breakthrough improvement strategies. Though Indian industries are exploring this improvement methodology to their advantage and reaping the benefits, not much has been presented and published regarding experience of Six Sigma in the food-processing industries. This paper is an effort to exemplify the application of Six Sigma quality improvement drive to one of the large-scale food-processing sectors in India. The paper discusses the phase wiz implementation of define, measure, analyze, improve, and control (DMAIC) on one of the chronic problems, variations in the weight of milk powder pouch. The paper wraps up with the improvements achieved and projected bottom-line gain to the unit by application of Six Sigma methodology.

  1. Detecting biotic and hydrogeochemical processes in large peat basins with Landsat TM imagery

    NASA Technical Reports Server (NTRS)

    Glaser, Paul H.

    1989-01-01

    A survey was made of three large peat basins in boreal North America with Landsat TM imagery and field sampling. False-color composites composed of Bands 2, 3, and 4 are particularly effective in discriminating the major vegetation types and the important hydrogeochemical processes in these peatlands. This imagery indicates that the discharge of alkaline groundwater provides one of the most important regional and local controls on peatland development.

  2. Evaluation of variational principle based model for LDPE large scale film blowing process

    NASA Astrophysics Data System (ADS)

    Kolarik, Roman; Zatloukal, Martin

    2013-04-01

    In this work, variational principle based film blowing model combined with Pearson and Petrie formulation, considering non-isothermal processing conditions and novel generalized Newtonian model allowing to capture steady shear and uniaxial extensional viscosities has been validated by using experimentally determined bubble shape and velocity profile for LDPE sample on large scale film blowing line. It has been revealed that the minute change in the flow activation energy can significantly influence the film stretching level.

  3. A hermetic sealing process for large irregularly shaped hybrid microcircuit enclosures

    NASA Technical Reports Server (NTRS)

    Stahler, M. R.

    1977-01-01

    A system for sealing vacuum baked hybrids in a dry inert atmosphere using an overlapping spot resistance weld is described. A unique electrode configuration and fixturing that permits sealing of large and irregularly shaped gold plated Kovar packages to the hermeticity requirements of MIL-STD-883 was discussed. Metallurgical considerations and comparisons to laser sealing were made. Problems encountered during the development and optimization of the process were highlighted. Solutions to plating, fixturing, warpage, weld splatter and cracked bead problems are presented.

  4. A framework for the direct evaluation of large deviations in non-Markovian processes

    NASA Astrophysics Data System (ADS)

    Cavallaro, Massimo; Harris, Rosemary J.

    2016-11-01

    We propose a general framework to simulate stochastic trajectories with arbitrarily long memory dependence and efficiently evaluate large deviation functions associated to time-extensive observables. This extends the ‘cloning’ procedure of Giardiná et al (2006 Phys. Rev. Lett. 96 120603) to non-Markovian systems. We demonstrate the validity of this method by testing non-Markovian variants of an ion-channel model and the totally asymmetric exclusion process, recovering results obtainable by other means.

  5. Extraterrestrial processing and manufacturing of large space systems, volume 1, chapters 1-6

    NASA Technical Reports Server (NTRS)

    Miller, R. H.; Smith, D. B. S.

    1979-01-01

    Space program scenarios for production of large space structures from lunar materials are defined. The concept of the space manufacturing facility (SMF) is presented. The manufacturing processes and equipment for the SMF are defined and the conceptual layouts are described for the production of solar cells and arrays, structures and joints, conduits, waveguides, RF equipment radiators, wire cables, and converters. A 'reference' SMF was designed and its operation requirements are described.

  6. Large Data at Small Universities: Astronomical processing using a computer classroom

    NASA Astrophysics Data System (ADS)

    Fuller, Nathaniel James; Clarkson, William I.; Fluharty, Bill; Belanger, Zach; Dage, Kristen

    2016-06-01

    The use of large computing clusters for astronomy research is becoming more commonplace as datasets expand, but access to these required resources is sometimes difficult for research groups working at smaller Universities. As an alternative to purchasing processing time on an off-site computing cluster, or purchasing dedicated hardware, we show how one can easily build a crude on-site cluster by utilizing idle cycles on instructional computers in computer-lab classrooms. Since these computers are maintained as part of the educational mission of the University, the resource impact on the investigator is generally low.By using open source Python routines, it is possible to have a large number of desktop computers working together via a local network to sort through large data sets. By running traditional analysis routines in an “embarrassingly parallel” manner, gains in speed are accomplished without requiring the investigator to learn how to write routines using highly specialized methodology. We demonstrate this concept here applied to 1. photometry of large-format images and 2. Statistical significance-tests for X-ray lightcurve analysis. In these scenarios, we see a speed-up factor which scales almost linearly with the number of cores in the cluster. Additionally, we show that the usage of the cluster does not severely limit performance for a local user, and indeed the processing can be performed while the computers are in use for classroom purposes.

  7. Intrusive LIPs: Deep crustal magmatic processes during the emplacement of Large Igneous Provinces

    NASA Astrophysics Data System (ADS)

    Richards, M. A.; Karlstrom, L.

    2011-12-01

    Large Igneous Provinces (LIPs) are characterized by magmatic activity on two distinct timescales. While these provinces have total active lifetimes of order 10-30 Ma, most of the erupted volume is emplaced within <1 Ma in many cases. The latter timescale is likely controlled by magmatic intrusion/evolution processes within the deep crust. We present seismic evidence for 5-15 km thick Moho-level ultramafic intrusive/cumulate layers underlying Phanerozoic LIPs worldwide [Ridley and Richards, 2010]. These deep crustal bodies are both observed and predicted to have volumes at least as large as the extrusive components of flood volcanism. The evidence for these layers is particularly clear for oceanic LIPs (plateaus). We hypothesize that thermally activated creep of the lower crust due to magma chamber emplacement controls a transition from largely extrusive to largely intrusive magmatism during mantle plume impingement on the lithosphere [Karlstrom and Richards, 2011]. We explore this hypothesis by modeling the thermomechanical evolution of Moho-level magma chambers. Comparing the timescale for viscoelastic relaxation of intrusion-related stresses with the timescale for sill formation and magma differentiation, we find that fracture processes leading to diking from Moho levels may plausibly be shut off on a timescale of ~1 Ma. Continued melt influx therefore results in intrusive magmatism, which may be manifest as plateau growth in oceanic settings. We suggest that maximum intrusion size may be limited by crustal thickness, resulting in smaller volume individual eruptions in oceanic versus continental LIPs.

  8. Removal of the anti-cancer drug methotrexate from water by advanced oxidation processes: Aerobic biodegradation and toxicity studies after treatment.

    PubMed

    Lutterbeck, Carlos Alexandre; Baginska, Ewelina; Machado, Ênio Leandro; Kümmerer, Klaus

    2015-12-01

    Anti-cancer drugs are discussed as high risk substances in regard to human health and considered as problematic for the environment. They are of potential environmental relevance due to their poor biodegradability and toxicological properties. Methotrexate (MTX) is an antimetabolite that was introduced in the pharmaceutical market in the 40's and still today is one of the most consumed cytotoxic compounds around the world. In the present study MTX was only partially biodegraded in the closed bottle test (CBT). Therefore, it was submitted to three different advanced oxidation processes (AOPs): UV/H2O2, UV/Fe(2+)/H2O2 and UV/TiO2. The irradiation was carried out with a Hg medium-pressure lamp during 256min whereas the analytical monitoring was done through LC-UV-MS/MS and DOC analysis. MTX was easily removed in all the irradiation experiments, while the highest mineralization values and rates were achieved by the UV/Fe(2+)/H2O2 treatment. The lowest resulted from the UV/H2O2 reactions. The UV/H2O2 treatment resulted in little biodegradable transformation products (TPs). However, the same treatment resulted in a reduction of the toxicity of MTX by forming less toxic TPs. Analysis by LC-UV-MS/MS revealed the existence of nine TPs formed during the photo-catalytic treatments. The pH of the solutions decreased from 6.4 (t 0min) to 5.15 in the UV/H2O2 and from 6.4 (t 0min) to 5.9 in the UV/TiO2 at the end of the experiments. The initial pH of the UV/Fe(2+)/H2O2 experiments was adjusted to 5 and after the addition of H2O2 the pH decreased to around 3 and remained in this range until the end of the treatments.

  9. Description and capabilities of the large-scale in situ vitrification process

    SciTech Connect

    Buelt, J.L.; Carter, J.G.

    1986-01-01

    An emerging thermal treatment process known as in situ vitrification is being developed to immobilize selected portions of radioactively contaminated soils. The process is a permanent remedial action that destroys solid and liquid organic contaminants and incorporates radionuclides and heavy metals into a glass and crystalline form. The process's flexibility in design and broad capabilities make it potentially adaptable to mixed and chemical wastes, as well. The process consists of an electrical power system for vitrifying contaminated soil, a hood to contain gaseous effluents, an off-gas treatment system, an off-gas cooling system, and a process control station. The process is mounted in three transportable trailers that can be easily moved from site to site. The process is capable of treating contaminated soils at least 13 m deep. The system components are designed to accommodate waste inclusions in the soil such as metals, combustibles, and large voids. Selectively applied to the more troublesome radioactively contaminated soils, in situ vitrification provides a potentially useful and permanent tool for remedial action.

  10. Response of deep and shallow tropical maritime cumuli to large-scale processes

    NASA Technical Reports Server (NTRS)

    Yanai, M.; Chu, J.-H.; Stark, T. E.; Nitta, T.

    1976-01-01

    The bulk diagnostic method of Yanai et al. (1973) and a simplified version of the spectral diagnostic method of Nitta (1975) are used for a more quantitative evaluation of the response of various types of cumuliform clouds to large-scale processes, using the same data set in the Marshall Islands area for a 100-day period in 1956. The dependence of the cloud mass flux distribution on radiative cooling, large-scale vertical motion, and evaporation from the sea is examined. It is shown that typical radiative cooling rates in the tropics tend to produce a bimodal distribution of mass spectrum exhibiting deep and shallow clouds. The bimodal distribution is further enhanced when the large-scale vertical motion is upward, and a nearly unimodal distribution of shallow clouds prevails when the relative cooling is compensated by the heating due to the large-scale subsidence. Both deep and shallow clouds are modulated by large-scale disturbances. The primary role of surface evaporation is to maintain the moisture flux at the cloud base.

  11. Modern approaches to processing large hyperspectral and multispectral aerospace data flows

    NASA Astrophysics Data System (ADS)

    Bondur, V. G.

    2014-12-01

    We consider approaches to processing large hyperspectral and multispectral imaging flows produced in aerospace monitoring for solving a wide range of problems of management of natural resources, environmental security, prevention of natural disasters and technogenic accidents, as well as problems of real economy, and basic and applied sciences. We analyze the specific features of the phases of hyperspectral data analysis and describe a software and hardware system that uses new and improved methods and algorithms for processing large flows of hyperspectral and other aerospace data and has a high-performance computer. This system contains different types of software for identifying the types of given objects by solving inverse problems of remote sensing as well as by analyzing their qualitative and quantitative characteristics, combined multiparameter processing of hyperspectral aerospace data, tracking the local changes including those related to changes in meteorological conditions and vegetation periods, detecting and identifying the types of small objects on the basis of analysis of individual parts of the image, detecting and identifying heat sources, etc. We bring examples of processing of hyperspectral and multispectral satellite images with the help of software and hardware tools developed.

  12. Development of atmospheric pressure plasma processing machine tool for large aperture optics

    NASA Astrophysics Data System (ADS)

    Su, Xing; Wu, Yangong; Zhang, Peng; Xin, Qiang; Wang, Bo

    2016-10-01

    In recent years, major projects, such as National Ignition Facility and Laser Mégajoule, have generated great demands for large aperture optics with high surface accuracy and low Subsurface Damage (SSD) at the mean time. In order to remove SSD and improve surface quality, optics is fabricated by sub-aperture polishing. However, the efficiency of the sub-aperture polishing has been a bottleneck step for the optics manufacturing. Atmospheric Pressure Plasma Processing (APPP) as an alternate method offers high potential for speeding up the polishing process. This technique is based on chemical etching, hence there is no physical contact and no damage is induced. In this paper, a fast polishing machine tool is presented which is designed for fast polishing of the large aperture optics using APPP. This machine tool employs 3PRS-XY hybrid structure as its framework. There is a platform in the 3PRS parallel module to support the plasma generating system. And the large work piece is placed on the XY stage. In order to realize the complex motion trajectory for polishing the freeform optics, five axis of the tool operate simultaneously. To overcome the complexity of inverse kinematics calculation, a dedicated motion control system is also designed for speeding up the motion response. For high removal rate, the individual influence of several key processing parameters is investigated. And under specific production condition, this machine tool offers a high material over 30mm3/min for fused silica substrates. This results shows that APPP machine tool has a strong potential for fast polishing large optics without introducing SSD.

  13. Characterization and aerobic biodegradation of selected monoterpenes

    SciTech Connect

    Misra, G.; Pavlostathis, S.G.; Li, J.; Purdue, E.M.

    1996-12-31

    Monoterpenes are biogenic chemicals and occur in abundance in nature. Large-scale industrial use of these chemicals has recently been initiated in an attempt to replace halogenated solvents and chlorofluorocarbons which have been implicated in the stratospheric depletion of ozone. This study examined four hydrocarbon monoterpenes (d-limonene, {alpha}-pinene, {gamma}-terpinene, and terpinolene) and four alcohols (arbanol, linalool, plinol, and {alpha}-terpineol). Water solubility, vapor pressure, and octanol/water partition coefficients were estimated. Aerobic biodegradability tests were conducted in batch reactors by utilizing forest soil extract and enriched cultures as inoculum. The hydrophobic nature and high volatility of the hydrocarbons restricted the investigation to relatively low aqueous concentrations. Each monoterpene was analyzed with a gas chromatograph equipped with a flame ionization detector after extraction from the aqueous phase with isooctane. Terpene mineralization was tested by monitoring liquid-phase carbon, CO{sub 2} production and biomass growth. All four hydrocarbons and two alcohols readily degraded under aerobic conditions. Plinol resisted degradation in assays using inocula from diverse sources, while arbanol degraded very slowly. The intrinsic biokinetics coefficients for the degradation of d-limonene and {alpha}-terpineol were estimated by using cultures enriched with the respective monoterpenes. Monoterpene biodegradation followed Monod kinetics.

  14. An automated workflow for parallel processing of large multiview SPIM recordings

    PubMed Central

    Schmied, Christopher; Steinbach, Peter; Pietzsch, Tobias; Preibisch, Stephan; Tomancak, Pavel

    2016-01-01

    Summary: Selective Plane Illumination Microscopy (SPIM) allows to image developing organisms in 3D at unprecedented temporal resolution over long periods of time. The resulting massive amounts of raw image data requires extensive processing interactively via dedicated graphical user interface (GUI) applications. The consecutive processing steps can be easily automated and the individual time points can be processed independently, which lends itself to trivial parallelization on a high performance computing (HPC) cluster. Here, we introduce an automated workflow for processing large multiview, multichannel, multiillumination time-lapse SPIM data on a single workstation or in parallel on a HPC cluster. The pipeline relies on snakemake to resolve dependencies among consecutive processing steps and can be easily adapted to any cluster environment for processing SPIM data in a fraction of the time required to collect it. Availability and implementation: The code is distributed free and open source under the MIT license http://opensource.org/licenses/MIT. The source code can be downloaded from github: https://github.com/mpicbg-scicomp/snakemake-workflows. Documentation can be found here: http://fiji.sc/Automated_workflow_for_parallel_Multiview_Reconstruction. Contact: schmied@mpi-cbg.de Supplementary information: Supplementary data are available at Bioinformatics online. PMID:26628585

  15. Forecast of Large Earthquakes Through Semi-periodicity Analysis of Labeled Point Processes

    NASA Astrophysics Data System (ADS)

    Quinteros Cartaya, C. B.; Nava Pichardo, F. A.; Glowacka, E.; Gómez Treviño, E.; Dmowska, R.

    2016-08-01

    Large earthquakes have semi-periodic behavior as a result of critically self-organized processes of stress accumulation and release in seismogenic regions. Hence, large earthquakes in a given region constitute semi-periodic sequences with recurrence times varying slightly from periodicity. In previous papers, it has been shown that it is possible to identify these sequences through Fourier analysis of the occurrence time series of large earthquakes from a given region, by realizing that not all earthquakes in the region need belong to the same sequence, since there can be more than one process of stress accumulation and release in the region. Sequence identification can be used to forecast earthquake occurrence with well determined confidence bounds. This paper presents improvements on the above mentioned sequence identification and forecasting method: the influence of earthquake size on the spectral analysis, and its importance in semi-periodic events identification are considered, which means that earthquake occurrence times are treated as a labeled point process; a revised estimation of non-randomness probability is used; a better estimation of appropriate upper limit uncertainties to use in forecasts is introduced; and the use of Bayesian analysis to evaluate the posterior forecast performance is applied. This improved method was successfully tested on synthetic data and subsequently applied to real data from some specific regions. As an example of application, we show the analysis of data from the northeastern Japan Arc region, in which one semi-periodic sequence of four earthquakes with M ≥ 8.0, having high non-randomness probability was identified. We compare the results of this analysis with those of the unlabeled point process analysis.

  16. [Effect of aerobic fermentation on the survival of Salmonella typhimurium (DT 104) and Escherichia coli in swine liquid manure].

    PubMed

    Herold, T; Kliche, R; Hensel, A

    1999-12-01

    In this study aerobic-thermophilic fermentation of untreated liquid pig manure was examined for the potential of inactivating pathogenic microorganisms. As microbial tracer organisms, Salmonella typhimurium DT 104 and Escherichia coli were used. An effective reduction of survival of these microorganisms could be demonstrated by aerobic fermentation at temperatures of 50 degrees C for at least 3 h. However, these optimal process conditions without the need of additional heating, can only be achieved by microbial substrate reduction. In contrast to the impact of temperature on hygienization processes, alteration of the pH value which occurs during fermentation had no or little influence on the tenacity of the tracer bacteria. Even under mesophilic reaction conditions the influence of the pH value was not measurable. A technical realisation of such an aerobic-thermophilic fermentation process for prophylactic disinfection is questionable since a large technical expenditure is necessary to control ammonia emission. Effective partial reduction of nitrogen, phosphate, and free carbon in liquid manure requires retention times of at least 48 h. However, thermophilic reaction conditions may ensure an effective hygienization of the final fermentation products.

  17. Hallucal grasping in Nycticebus coucang: further implications for the functional significance of a large peroneal process.

    PubMed

    Kingston, Amanda K; Boyer, Doug M; Patel, Biren A; Larson, Susan G; Stern, Jack T

    2010-01-01

    Euprimate grasping feet are characterized by a suite of morphological traits, including an enlarged peroneal process on the base of the first metatarsal, which serves as the insertion site of the peroneus longus muscle. In prosimians, a large process has typically been associated with a powerful hallucal grasp via the contraction of the peroneus longus to adduct the hallux. Recent electromyography (EMG) studies have documented that peroneus longus does not contribute substantially to hallucal grasping in lemurids (Boyer et al., 2007). However, non-lemurid prosimians have a I-V opposable grasp complex that is morphologically different and phylogenetically more primitive than the I-II adductor grasp complex of the lemurids previously studied. Therefore, it is possible that peroneus longus did function during grasping in early euprimates, but lost this function in large-bodied lemurids. The present study tests the hypothesis that a large peroneal process is related to powerful grasping ability in primates displaying the more primitive I-V grasp complex. We use EMG to evaluate the recruitment of peroneus longus, other crural muscles, and adductor hallucis in static and locomotor grasping activities of the slow loris (Nycticebus coucang). Results show that peroneus longus is active during grasping behaviors that require the subject to actively resist inversion of the foot, and likely contributes to a hallucal grasp in these activities. Peroneus longus activity level does not differ between grasping and power grasping activities, nor does it differ between grasping and non-grasping locomotor modes. Conversely, the digital flexors and hallucal adductor are recruited at higher levels during power grasping and grasping locomotor modes. Consequently, we reject the hypothesis that an enlarged peroneal process represents an adaptation specifically to enhance the power of the I-V grasp, but accept that the muscle likely plays a role in adducting the hallux during grasping

  18. Leveraging human oversight and intervention in large-scale parallel processing of open-source data

    NASA Astrophysics Data System (ADS)

    Casini, Enrico; Suri, Niranjan; Bradshaw, Jeffrey M.

    2015-05-01

    The popularity of cloud computing along with the increased availability of cheap storage have led to the necessity of elaboration and transformation of large volumes of open-source data, all in parallel. One way to handle such extensive volumes of information properly is to take advantage of distributed computing frameworks like Map-Reduce. Unfortunately, an entirely automated approach that excludes human intervention is often unpredictable and error prone. Highly accurate data processing and decision-making can be achieved by supporting an automatic process through human collaboration, in a variety of environments such as warfare, cyber security and threat monitoring. Although this mutual participation seems easily exploitable, human-machine collaboration in the field of data analysis presents several challenges. First, due to the asynchronous nature of human intervention, it is necessary to verify that once a correction is made, all the necessary reprocessing is done in chain. Second, it is often needed to minimize the amount of reprocessing in order to optimize the usage of resources due to limited availability. In order to improve on these strict requirements, this paper introduces improvements to an innovative approach for human-machine collaboration in the processing of large amounts of open-source data in parallel.

  19. Laser processing system for stitching structured patterns on large 3D parts

    NASA Astrophysics Data System (ADS)

    Cano Zuriguel, Rafael; Saludes Rodil, Sergio

    2015-07-01

    The paper addresses the development of laser based equipment to structure large surfaces (1×1×0.5m - 3×3×1.5ft) that are shaped in three dimensions. A mechanic-optical system to process curved surfaces with an acceptance angle of up to 267° is presented. The challenge is to control the combined motion of the beam delivery system with respect to distortion of the motifs and positioning tolerances. The project starting Technology Readiness Level (TRL) was 5. Currently the project is under development and at the end of September 2015 the project will reach TRL 7 after industrial-like environment testing. The proposed system will enable manufacturers to offer individualized marking for large products.

  20. A coherent light scanner for optical processing of large format transparencies

    NASA Technical Reports Server (NTRS)

    Callen, W. R.; Weaver, J. E.; Shackelford, R. G.; Walsh, J. R.

    1975-01-01

    A laser scanner is discussed in which the scanning beam is random-access addressable and perpendicular to the image input plane and the irradiance of the scanned beam is controlled so that a constant average irradiance is maintained after passage through the image plane. The scanner's optical system and design are described, and its performance is evaluated. It is noted that with this scanner, data in the form of large-format transparencies can be processed without the expense, space, maintenance, and precautions attendant to the operation of a high-power laser with large-aperture collimating optics. It is shown that the scanned format as well as the diameter of the scanning beam may be increased by simple design modifications and that higher scan rates can be achieved at the expense of resolution by employing acousto-optic deflectors with different relay optics.

  1. Large-scale brain networks emerge from dynamic processing of musical timbre, key and rhythm.

    PubMed

    Alluri, Vinoo; Toiviainen, Petri; Jääskeläinen, Iiro P; Glerean, Enrico; Sams, Mikko; Brattico, Elvira

    2012-02-15

    We investigated the neural underpinnings of timbral, tonal, and rhythmic features of a naturalistic musical stimulus. Participants were scanned with functional Magnetic Resonance Imaging (fMRI) while listening to a stimulus with a rich musical structure, a modern tango. We correlated temporal evolutions of timbral, tonal, and rhythmic features of the stimulus, extracted using acoustic feature extraction procedures, with the fMRI time series. Results corroborate those obtained with controlled stimuli in previous studies and highlight additional areas recruited during musical feature processing. While timbral feature processing was associated with activations in cognitive areas of the cerebellum, and sensory and default mode network cerebrocortical areas, musical pulse and tonality processing recruited cortical and subcortical cognitive, motor and emotion-related circuits. In sum, by combining neuroimaging, acoustic feature extraction and behavioral methods, we revealed the large-scale cognitive, motor and limbic brain circuitry dedicated to acoustic feature processing during listening to a naturalistic stimulus. In addition to these novel findings, our study has practical relevance as it provides a powerful means to localize neural processing of individual acoustical features, be it those of music, speech, or soundscapes, in ecological settings.

  2. WWOX loss activates aerobic glycolysis.

    PubMed

    Abu-Remaileh, Muhannad; Seewaldt, Victoria L; Aqeilan, Rami I

    2015-01-01

    Cancer cells undergo reprogramming of glucose metabolism to limit energy production to glycolysis-a state known as "aerobic glycolysis." Hypoxia-inducible factor 1 (HIF1α) is a transcription factor that regulates many genes responsible for this switch. As discussed here, new data suggest that the tumor suppressor WW domain-containing oxidoreductase (WWOX) modulates HIF1α, thereby regulating this metabolic state.

  3. WWOX loss activates aerobic glycolysis

    PubMed Central

    Abu-Remaileh, Muhannad; Seewaldt, Victoria L; Aqeilan, Rami I

    2015-01-01

    Cancer cells undergo reprogramming of glucose metabolism to limit energy production to glycolysis—a state known as “aerobic glycolysis.” Hypoxia-inducible factor 1 (HIF1α) is a transcription factor that regulates many genes responsible for this switch. As discussed here, new data suggest that the tumor suppressor WW domain-containing oxidoreductase (WWOX) modulates HIF1α, thereby regulating this metabolic state. PMID:27308416

  4. Organizing the Extremely Large LSST Database forReal-Time Astronomical Processing

    SciTech Connect

    Becla, Jacek; Lim, Kian-Tat; Monkewitz, Serge; Nieto-Santisteban, Maria; Thakar, Ani; /Johns Hopkins U.

    2007-11-07

    The Large Synoptic Survey Telescope (LSST) will catalog billions of astronomical objects and trillions of sources, all of which will be stored and managed by a database management system. One of the main challenges is real-time alert generation. To generate alerts, up to 100K new difference detections have to be cross-correlated with the huge historical catalogs, and then further processed to prune false alerts. This paper explains the challenges, the implementation of the LSST Association Pipeline and the database organization strategies we are planning to use to meet the real-time requirements, including data partitioning, parallelization, and pre-loading.

  5. Loss aversion, large deviation preferences and optimal portfolio weights for some classes of return processes

    NASA Astrophysics Data System (ADS)

    Duffy, Ken; Lobunets, Olena; Suhov, Yuri

    2007-05-01

    We propose a model of a loss averse investor who aims to maximize his expected wealth under certain constraints. The constraints are that he avoids, with high probability, incurring an (suitably defined) unacceptable loss. The methodology employed comes from the theory of large deviations. We explore a number of fundamental properties of the model and illustrate its desirable features. We demonstrate its utility by analyzing assets that follow some commonly used financial return processes: Fractional Brownian Motion, Jump Diffusion, Variance Gamma and Truncated Lévy.

  6. Conservation laws for collisional and turbulent transport processes in toroidal plasmas with large mean flows

    NASA Astrophysics Data System (ADS)

    Sugama, H.; Nunami, M.; Nakata, M.; Watanabe, T.-H.

    2017-02-01

    A novel gyrokinetic formulation is presented by including collisional effects into the Lagrangian variational principle to yield the governing equations for background and turbulent electromagnetic fields and gyrocenter distribution functions, which can simultaneously describe classical, neoclassical, and turbulent transport processes in toroidal plasmas with large toroidal flows on the order of the ion thermal velocity. Noether's theorem modified for collisional systems and the collision operator given in terms of Poisson brackets are applied to derivation of the particle, energy, and toroidal momentum balance equations in the conservative forms, which are desirable properties for long-time global transport simulation.

  7. Use of process monitoring for verifying facility design of large-scale reprocessing plants

    SciTech Connect

    Hakkila, E.A.; Zack, N.R. ); Ehinger, M.H. ); Franssen, F. )

    1991-01-01

    During the decade of the 1990s, the International Atomic Energy Agency (IAEA) faces the challenge of implementing safeguards in large, new reprocessing facilities. The Agency will be involved in the design, construction, checkout and initial operation of these new facilities to ensure effective safeguards are implemented. One aspect of the Agency involvement is in the area of design verification. The United States Support Program has initiated a task to develop methods for applying process data collection and validation during the cold commissioning phase of plant construction. This paper summarizes the results of this task. 14 refs., 1 tab.

  8. Large area low cost processing for CIS photovoltaics. Final technical report

    SciTech Connect

    B. Basol; G. Norsworthy; C. Leidholm; A. Halani; R. Roe; V. Kapur

    1999-07-22

    An ink coating method was developed for CIS absorber deposition. The technique involves four processing steps: (1) preparation of a Cu-In alloy powder, (2) preparation of an ink using this powder, (3) deposition of the ink on a substrate in the form of a precursor layer, and (4) selenization to convert the Cu-In precursor into a fused CIS film. Absorbers grown by this low-cost, large-area method were used in the fabrication of 10.5% efficient solar cells.

  9. Aerobic Metabolism of Streptococcus agalactiae

    PubMed Central

    Mickelson, M. N.

    1967-01-01

    Streptococcus agalactiae cultures possess an aerobic pathway for glucose oxidation that is strongly inhibited by cyanide. The products of glucose oxidation by aerobically grown cells of S. agalactiae 50 are lactic and acetic acids, acetylmethylcarbinol, and carbon dioxide. Glucose degradation products by aerobically grown cells, as percentage of glucose carbon, were 52 to 61% lactic acid, 20 to 23% acetic acid, 5.5 to 6.5% acetylmethylcarbinol, and 14 to 16% carbon dioxide. There was no evidence for a pentose cycle or a tricarboxylic acid cycle. Crude cell-free extracts of S. agalactiae 50 possessed a strong reduced nicotinamide adenine dinucleotide (NADH2) oxidase that is also cyanide-sensitive. Dialysis or ultrafiltration of the crude, cell-free extract resulted in loss of NADH2 oxidase activity. Oxidase activity was restored to the inactive extract by addition of the ultrafiltrate or by addition of menadione or K3Fe(CN)6. Noncytochrome iron-containing pigments were present in cell-free extracts of S. agalactiae. The possible participation of these pigments in the respiration of S. agalactiae is presently being studied. PMID:4291090

  10. A Multilateral Use and Processing of A Large Bibliographic Database for Research Information

    NASA Astrophysics Data System (ADS)

    Konishi, Osamu; Obayashi, Haruo

    In order to explain the multilateral use of bibliographic database in research activities, nuclear fusion research field as the comprehensive science was selected. The processing method of the above mentioned database is mainly described. Considering advantages of the bibliographic and indexed information of such database, its use is classified into three types: 1. To use for reference information, 2. To obtain facts and knowledge from information, and 3. To process and analyse information. Each sample corresponding to the above is introduced as follows, and the usefulness of a large scale database is made clear. 1) Use of online search in research activities, 2) Construction of scientific terms list utilizing keywords and their frequency in the database, and 3) To analyse bibliographic information metrically and evaluate research. This is an application of scientometrics.

  11. Large area ceramic thin films on plastics: A versatile route via solution processing

    SciTech Connect

    Kozuka, H.; Yamano, A.; Uchiyama, H.; Takahashi, M.; Fukui, T.; Yoki, M.; Akase, T.

    2012-01-01

    A new general route for large area, submicron thick ceramic thin films (crystalline metal oxide thin films) on plastic substrates is presented, where the crystallization of films is guaranteed by a firing process. Gel films are deposited on silicon substrates with a release layer and fired to be ceramic films, followed by transferring onto plastic substrates using adhesives. The ceramic films thus fabricated on plastics exhibit a certain degree of flexibility, implying the possibility of the technique to be applied to high-throughput roll-to-roll processes. Using this technique, we successfully realized transparent anatase thin films that provide high optical reflectance and transparent indium tin oxide thin films that exhibit electrical conductivity on polycarbonate and acrylic resin substrates, respectively. Crystallographically oriented zinc oxide films and patterned zinc oxide films are also demonstrated to be realized on acrylic resin substrates.

  12. Functional Traits Reveal Processes Driving Natural Afforestation at Large Spatial Scales

    PubMed Central

    Mason, Norman W. H.; Wiser, Susan K.; Richardson, Sarah J.; Thorsen, Michael J.; Holdaway, Robert J.; Dray, Stéphane; Thomson, Fiona J.; Carswell, Fiona E.

    2013-01-01

    An understanding of the processes governing natural afforestation over large spatial scales is vital for enhancing forest carbon sequestration. Models of tree species occurrence probability in non-forest vegetation could potentially identify the primary variables determining natural afforestation. However, inferring processes governing afforestation using tree species occurrence is potentially problematic, since it is impossible to know whether observed occurrences are due to recruitment or persistence of existing trees following disturbance. Plant functional traits have the potential to reveal the processes by which key environmental and land cover variables influence afforestation. We used 10,061 survey plots to identify the primary environmental and land cover variables influencing tree occurrence probability in non-forest vegetation in New Zealand. We also examined how these variables influenced diversity of functional traits linked to plant ecological strategy and dispersal ability. Mean annual temperature was the most important environmental predictor of tree occurrence. Local woody cover and distance to forest were the most important land cover variables. Relationships between these variables and ecological strategy traits revealed a trade-off between ability to compete for light and colonize sites that were marginal for tree occurrence. Biotically dispersed species occurred less frequently with declining temperature and local woody cover, suggesting that abiotic stress limited their establishment and that biotic dispersal did not increase ability to colonize non-woody vegetation. Functional diversity for ecological strategy traits declined with declining temperature and woody cover and increasing distance to forest. Functional diversity for dispersal traits showed the opposite trend. This suggests that low temperatures and woody cover and high distance to forest may limit tree species establishment through filtering on ecological strategy traits, but not on

  13. Functional traits reveal processes driving natural afforestation at large spatial scales.

    PubMed

    Mason, Norman W H; Wiser, Susan K; Richardson, Sarah J; Thorsen, Michael J; Holdaway, Robert J; Dray, Stéphane; Thomson, Fiona J; Carswell, Fiona E

    2013-01-01

    An understanding of the processes governing natural afforestation over large spatial scales is vital for enhancing forest carbon sequestration. Models of tree species occurrence probability in non-forest vegetation could potentially identify the primary variables determining natural afforestation. However, inferring processes governing afforestation using tree species occurrence is potentially problematic, since it is impossible to know whether observed occurrences are due to recruitment or persistence of existing trees following disturbance. Plant functional traits have the potential to reveal the processes by which key environmental and land cover variables influence afforestation. We used 10,061 survey plots to identify the primary environmental and land cover variables influencing tree occurrence probability in non-forest vegetation in New Zealand. We also examined how these variables influenced diversity of functional traits linked to plant ecological strategy and dispersal ability. Mean annual temperature was the most important environmental predictor of tree occurrence. Local woody cover and distance to forest were the most important land cover variables. Relationships between these variables and ecological strategy traits revealed a trade-off between ability to compete for light and colonize sites that were marginal for tree occurrence. Biotically dispersed species occurred less frequently with declining temperature and local woody cover, suggesting that abiotic stress limited their establishment and that biotic dispersal did not increase ability to colonize non-woody vegetation. Functional diversity for ecological strategy traits declined with declining temperature and woody cover and increasing distance to forest. Functional diversity for dispersal traits showed the opposite trend. This suggests that low temperatures and woody cover and high distance to forest may limit tree species establishment through filtering on ecological strategy traits, but not on

  14. Adapting a large database of point of care summarized guidelines: a process description

    PubMed Central

    Van de Velde, Stijn; Aertgeerts, Bert; Goossens, Martine; Fauquert, Benjamin; Kunnamo, Ilka; Van Royen, Paul

    2015-01-01

    Abstract Rationale, aims and objectives Questions posed at the point of care (POC) can be answered using POC summarized guidelines. To implement a national POC information resource, we subscribed to a large database of POC summarized guidelines to complement locally available guidelines. Our challenge was in developing a sustainable strategy for adapting almost 1000 summarized guidelines. The aim of this paper was to describe our process for adapting a database of POC summarized guidelines. Methods An adaptation process based on the ADAPTE framework was tailored to be used by a heterogeneous group of participants. Guidelines were assessed on content and on applicability to the Belgian context. To improve efficiency, we chose to first aim our efforts towards those guidelines most important to primary care doctors. Results Over a period of 3 years, we screened about 80% of 1000 international summarized guidelines. For those guidelines identified as most important for primary care doctors, we noted that in about half of the cases, remarks were made concerning content. On the other hand, at least two‐thirds of all screened guidelines required no changes when evaluating their local usability. Conclusions Adapting a large body of POC summarized guidelines using a formal adaptation process is possible, even when faced with limited resources. This can be done by creating an efficient and collaborative effort and ensuring user‐friendly procedures. Our experiences show that even though in most cases guidelines can be adopted without adaptations, careful review of guidelines developed in a different context remains necessary. Streamlining international efforts in adapting international POC information resources and adopting similar adaptation processes may lessen duplication efforts and prove more cost‐effective.

  15. Breeding and Genetics Symposium: really big data: processing and analysis of very large data sets.

    PubMed

    Cole, J B; Newman, S; Foertter, F; Aguilar, I; Coffey, M

    2012-03-01

    15 m. Large data sets also create challenges for the delivery of genetic evaluations that must be overcome in a way that does not disrupt the transition from conventional to genomic evaluations. Processing time is important, especially as real-time systems for on-farm decisions are developed. The ultimate value of these systems is to decrease time-to-results in research, increase accuracy in genomic evaluations, and accelerate rates of genetic improvement.

  16. Schwinger-Dyson equations in large-N quantum field theories and nonlinear random processes

    SciTech Connect

    Buividovich, P. V.

    2011-02-15

    We propose a stochastic method for solving Schwinger-Dyson equations in large-N quantum field theories. Expectation values of single-trace operators are sampled by stationary probability distributions of the so-called nonlinear random processes. The set of all the histories of such processes corresponds to the set of all planar diagrams in the perturbative expansions of the expectation values of singlet operators. We illustrate the method on examples of the matrix-valued scalar field theory and the Weingarten model of random planar surfaces on the lattice. For theories with compact field variables, such as sigma models or non-Abelian lattice gauge theories, the method does not converge in the physically most interesting weak-coupling limit. In this case one can absorb the divergences into a self-consistent redefinition of expansion parameters. A stochastic solution of the self-consistency conditions can be implemented as a 'memory' of the random process, so that some parameters of the process are estimated from its previous history. We illustrate this idea on the two-dimensional O(N) sigma model. The extension to non-Abelian lattice gauge theories is discussed.

  17. Biologically inspired large scale chemical sensor arrays and embedded data processing

    NASA Astrophysics Data System (ADS)

    Marco, S.; Gutiérrez-Gálvez, A.; Lansner, A.; Martinez, D.; Rospars, J. P.; Beccherelli, R.; Perera, A.; Pearce, T.; Vershure, P.; Persaud, K.

    2013-05-01

    Biological olfaction outperforms chemical instrumentation in specificity, response time, detection limit, coding capacity, time stability, robustness, size, power consumption, and portability. This biological function provides outstanding performance due, to a large extent, to the unique architecture of the olfactory pathway, which combines a high degree of redundancy, an efficient combinatorial coding along with unmatched chemical information processing mechanisms. The last decade has witnessed important advances in the understanding of the computational primitives underlying the functioning of the olfactory system. EU Funded Project NEUROCHEM (Bio-ICT-FET- 216916) has developed novel computing paradigms and biologically motivated artefacts for chemical sensing taking inspiration from the biological olfactory pathway. To demonstrate this approach, a biomimetic demonstrator has been built featuring a large scale sensor array (65K elements) in conducting polymer technology mimicking the olfactory receptor neuron layer, and abstracted biomimetic algorithms have been implemented in an embedded system that interfaces the chemical sensors. The embedded system integrates computational models of the main anatomic building blocks in the olfactory pathway: the olfactory bulb, and olfactory cortex in vertebrates (alternatively, antennal lobe and mushroom bodies in the insect). For implementation in the embedded processor an abstraction phase has been carried out in which their processing capabilities are captured by algorithmic solutions. Finally, the algorithmic models are tested with an odour robot with navigation capabilities in mixed chemical plumes

  18. Morphotectonic evolution of passive margins undergoing active surface processes: large-scale experiments using numerical models.

    NASA Astrophysics Data System (ADS)

    Beucher, Romain; Huismans, Ritske S.

    2016-04-01

    Extension of the continental lithosphere can lead to the formation of a wide range of rifted margins styles with contrasting tectonic and geomorphological characteristics. It is now understood that many of these characteristics depend on the manner extension is distributed depending on (among others factors) rheology, structural inheritance, thermal structure and surface processes. The relative importance and the possible interactions of these controlling factors is still largely unknown. Here we investigate the feedbacks between tectonics and the transfers of material at the surface resulting from erosion, transport, and sedimentation. We use large-scale (1200 x 600 km) and high-resolution (~1km) numerical experiments coupling a 2D upper-mantle-scale thermo-mechanical model with a plan-form 2D surface processes model (SPM). We test the sensitivity of the coupled models to varying crust-lithosphere rheology and erosional efficiency ranging from no-erosion to very efficient erosion. We discuss how fast, when and how the topography of the continents evolves and how it can be compared to actual passive margins escarpment morphologies. We show that although tectonics is the main factor controlling the rift geometry, transfers of masses at the surface affect the timing of faulting and the initiation of sea-floor spreading. We discuss how such models may help to understand the evolution of high-elevated passive margins around the world.

  19. The large-scale process of microbial carbonate precipitation for nickel remediation from an industrial soil.

    PubMed

    Zhu, Xuejiao; Li, Weila; Zhan, Lu; Huang, Minsheng; Zhang, Qiuzhuo; Achal, Varenyam

    2016-12-01

    Microbial carbonate precipitation is known as an efficient process for the remediation of heavy metals from contaminated soils. In the present study, a urease positive bacterial isolate, identified as Bacillus cereus NS4 through 16S rDNA sequencing, was utilized on a large scale to remove nickel from industrial soil contaminated by the battery industry. The soil was highly contaminated with an initial total nickel concentration of approximately 900 mg kg(-1). The soluble-exchangeable fraction was reduced to 38 mg kg(-1) after treatment. The primary objective of metal stabilization was achieved by reducing the bioavailability through immobilizing the nickel in the urease-driven carbonate precipitation. The nickel removal in the soils contributed to the transformation of nickel from mobile species into stable biominerals identified as calcite, vaterite, aragonite and nickelous carbonate when analyzed under XRD. It was proven that during precipitation of calcite, Ni(2+) with an ion radius close to Ca(2+) was incorporated into the CaCO3 crystal. The biominerals were also characterized by using SEM-EDS to observe the crystal shape and Raman-FTIR spectroscopy to predict responsible bonding during bioremediation with respect to Ni immobilization. The electronic structure and chemical-state information of the detected elements during MICP bioremediation process was studied by XPS. This is the first study in which microbial carbonate precipitation was used for the large-scale remediation of metal-contaminated industrial soil.

  20. Advanced optical sensing and processing technologies for the distributed control of large flexible spacecraft

    NASA Technical Reports Server (NTRS)

    Williams, G. M.; Fraser, J. C.

    1991-01-01

    The objective was to examine state-of-the-art optical sensing and processing technology applied to control the motion of flexible spacecraft. Proposed large flexible space systems, such an optical telescopes and antennas, will require control over vast surfaces. Most likely distributed control will be necessary involving many sensors to accurately measure the surface. A similarly large number of actuators must act upon the system. The used technical approach included reviewing proposed NASA missions to assess system needs and requirements. A candidate mission was chosen as a baseline study spacecraft for comparison of conventional and optical control components. Control system requirements of the baseline system were used for designing both a control system containing current off-the-shelf components and a system utilizing electro-optical devices for sensing and processing. State-of-the-art surveys of conventional sensor, actuator, and processor technologies were performed. A technology development plan is presented that presents a logical, effective way to develop and integrate advancing technologies.

  1. A versatile MEMS bimorph actuator with large vertical displacement and high resolution: Design and fabrication process

    NASA Astrophysics Data System (ADS)

    Rangra, Aarushee; Maninder, K.; Soni, Shilpi; Rangra, K. J.

    2016-04-01

    This paper presents design, simulation results and envisaged fabrication process for a versatile MEMS bimorph actuator with large out of plane displacement and high resolution. A comparative study of mechanical, thermal and electrical response of the micro-actuator is presented by using two well-known MEMS simulation tools. The bimorph structure measuring 700 × 1280 mm2 is fully integrable with CMOS fabrication process. It is indented for tunable filter applications where the precise vertical motion of the payload, the top metallic electrode anchored rigidly to bimorph `springs' spans the vertical range of 250-300 microns with submicron resolution. Each bimorph spring resembles a hair pin structure and is composed of materials with large difference in thermal expansion coefficients e.g. electroplated gold and polysilicon for optimal out-of-the plane deflection. The novel structure can also be configured for analog micro-mirror based optical and IR spectroscopy applications by controlling the actuation bias and top electrode surface parameters.

  2. Criticality in large-scale brain FMRI dynamics unveiled by a novel point process analysis.

    PubMed

    Tagliazucchi, Enzo; Balenzuela, Pablo; Fraiman, Daniel; Chialvo, Dante R

    2012-01-01

    Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of gradual and continuous changes in the brain blood oxygenated level dependent (BOLD) signal. Departing from that approach, recent work has shown that equivalent results can be obtained by inspecting only the relatively large amplitude BOLD signal peaks, suggesting that relevant information can be condensed in discrete events. This idea is further explored here to demonstrate how brain dynamics at resting state can be captured just by the timing and location of such events, i.e., in terms of a spatiotemporal point process. The method allows, for the first time, to define a theoretical framework in terms of an order and control parameter derived from fMRI data, where the dynamical regime can be interpreted as one corresponding to a system close to the critical point of a second order phase transition. The analysis demonstrates that the resting brain spends most of the time near the critical point of such transition and exhibits avalanches of activity ruled by the same dynamical and statistical properties described previously for neuronal events at smaller scales. Given the demonstrated functional relevance of the resting state brain dynamics, its representation as a discrete process might facilitate large-scale analysis of brain function both in health and disease.

  3. Which processes shape stellar population gradients of massive galaxies at large radii?

    NASA Astrophysics Data System (ADS)

    Hirschmann, Michaela

    2016-08-01

    We investigate the differential impact of physical mechanisms, mergers (stellar accretion) and internal energetic phenomena, on the evolution of stellar population gradients in massive, present-day galaxies employing a set of high-resolution, cosmological zoom simulations. We demonstrate that negative metallicity and color gradients at large radii (>2Reff) originate from the accretion of metal-poor stellar systems. At larger radii, galaxies become typically more dominated by stars accreted from satellite galaxies in major and minor mergers. However, only strong galactic winds can sufficiently reduce the metallicity content of the accreted stars to realistically steepen the outer metallicity and colour gradients in agreement with present-day observations. In contrast, the gradients of the models without winds are inconsistent with observations (too flat). In the wind model, colour and metallicity gradients are significantly steeper for systems which have accreted stars in minor mergers, while galaxies with major mergers have relatively flat gradients, confirming previous results. This analysis greatly highlights the importance of both energetic processes and merger events for stellar population properties of massive galaxies at large radii. Our results are expected to significantly contribute to the interpretation of current and up-coming IFU surveys (like MaNGA and Califa), which in turn can help to better constrain still uncertain models for energetic processes in simulations.

  4. Mosaic construction, processing, and review of very large electron micrograph composites

    NASA Astrophysics Data System (ADS)

    Vogt, Robert C., III; Trenkle, John M.; Harmon, Laurel A.

    1996-11-01

    A system of programs is described for acquisition, mosaicking, cueing and interactive review of large-scale transmission electron micrograph composite images. This work was carried out as part of a final-phase clinical analysis study of a drug for the treatment of diabetic peripheral neuropathy. MOre than 500 nerve biopsy samples were prepared, digitally imaged, processed, and reviewed. For a given sample, typically 1000 or more 1.5 megabyte frames were acquired, for a total of between 1 and 2 gigabytes of data per sample. These frames were then automatically registered and mosaicked together into a single virtual image composite, which was subsequently used to perform automatic cueing of axons and axon clusters, as well as review and marking by qualified neuroanatomists. Statistics derived from the review process were used to evaluate the efficacy of the drug in promoting regeneration of myelinated nerve fibers. This effort demonstrates a new, entirely digital capability for doing large-scale electron micrograph studies, in which all of the relevant specimen data can be included at high magnification, as opposed to simply taking a random sample of discrete locations. It opens up the possibility of a new era in electron microscopy--one which broadens the scope of questions that this imaging modality can be used to answer.

  5. Methane Emission From the Congo Deep Sea Fan and Subsequent Aerobic Oxidation in the Quaternary Tropical Atlantic

    NASA Astrophysics Data System (ADS)

    Handley, L.; Cooke, M. P.; Talbot, H. M.; Wagner, T.

    2008-12-01

    The Congo Fan is a well-documented region of important methane (CH4) storage and gas seepage: gas hydrates abound at and just below the sediment surface as do large deeply-buried reservoirs of thermogenic methane linked with hydrocarbon source rocks. In the Congo Fan, both sources of methane are intimately connected through a complex network of faults, structuring this massive sediment wedge in a unique way. Methane release from both reservoirs has the potential to drive or respond to changes in local and global climate, thus causing changes in ocean chemical properties and biotic responses. Understanding these poorly-constrained mechanisms of methane emission and reconstructing the history of past emissions in the ocean is the main focus of our study. The ultimate fate of CH4 is, typically, its oxidation to CO2; this process can occur aerobically and anaerobically. Compared to anaerobic processes, aerobic methane oxidation, and its underlying mechanisms and possible feedbacks for the ocean-climate system, has received little attention. Here we present molecular evidence from Congo Fan sediments for aerobic methane oxidation and highlight how the process may play a previously unrecognised role in carbon cycling and oxygen availability in the water column. Bacteriohopanepolyols (BHPs) are lipid membrane constituents and occur with a wide range of structural and functional variability in many bacteria. Amino-BHPs are produced in large abundances by methane-oxidising bacteria and the 35-aminobacteriohopane-30,31,32,33,34-pentol (aminopentol) is a highly specific biomarker for aerobic methane oxidation. The Congo Fan record (ODP Leg 175, Site 1075; 2996 m depth) spans the last 1 Myr and reveals remarkable organic biomarker preservation, with a suite of 13 different BHPs identified in most sediment horizons, including aminopentol. Aminopentol abundance varies widely throughout the section and appears to do so cyclically, with markedly greater concentrations between ca

  6. GMP Cryopreservation of Large Volumes of Cells for Regenerative Medicine: Active Control of the Freezing Process

    PubMed Central

    Massie, Isobel; Selden, Clare; Hodgson, Humphrey; Gibbons, Stephanie; Morris, G. John

    2014-01-01

    Cryopreservation protocols are increasingly required in regenerative medicine applications but must deliver functional products at clinical scale and comply with Good Manufacturing Process (GMP). While GMP cryopreservation is achievable on a small scale using a Stirling cryocooler-based controlled rate freezer (CRF) (EF600), successful large-scale GMP cryopreservation is more challenging due to heat transfer issues and control of ice nucleation, both complex events that impact success. We have developed a large-scale cryocooler-based CRF (VIA Freeze) that can process larger volumes and have evaluated it using alginate-encapsulated liver cell (HepG2) spheroids (ELS). It is anticipated that ELS will comprise the cellular component of a bioartificial liver and will be required in volumes of ∼2 L for clinical use. Sample temperatures and Stirling cryocooler power consumption was recorded throughout cooling runs for both small (500 μL) and large (200 mL) volume samples. ELS recoveries were assessed using viability (FDA/PI staining with image analysis), cell number (nuclei count), and function (protein secretion), along with cryoscanning electron microscopy and freeze substitution techniques to identify possible injury mechanisms. Slow cooling profiles were successfully applied to samples in both the EF600 and the VIA Freeze, and a number of cooling and warming profiles were evaluated. An optimized cooling protocol with a nonlinear cooling profile from ice nucleation to −60°C was implemented in both the EF600 and VIA Freeze. In the VIA Freeze the nucleation of ice is detected by the control software, allowing both noninvasive detection of the nucleation event for quality control purposes and the potential to modify the cooling profile following ice nucleation in an active manner. When processing 200 mL of ELS in the VIA Freeze—viabilities at 93.4%±7.4%, viable cell numbers at 14.3±1.7 million nuclei/mL alginate, and protein secretion at 10.5±1.7

  7. Conditionally Averaged Large-Scale Motions in the Neutral Atmospheric Boundary Layer: Insights for Aeolian Processes

    NASA Astrophysics Data System (ADS)

    Jacob, Chinthaka; Anderson, William

    2017-01-01

    Aeolian erosion of flat, arid landscapes is induced (and sustained) by the aerodynamic surface stress imposed by flow in the atmospheric surface layer. Conceptual models typically indicate that sediment mass flux, Q (via saltation or drift), scales with imposed aerodynamic stress raised to some exponent, n, where n > 1. This scaling demonstrates the importance of turbulent fluctuations in driving aeolian processes. In order to illustrate the importance of surface-stress intermittency in aeolian processes, and to elucidate the role of turbulence, conditional averaging predicated on aerodynamic surface stress has been used within large-eddy simulation of atmospheric boundary-layer flow over an arid, flat landscape. The conditional-sampling thresholds are defined based on probability distribution functions of surface stress. The simulations have been performed for a computational domain with ≈ 25 H streamwise extent, where H is the prescribed depth of the neutrally-stratified boundary layer. Thus, the full hierarchy of spatial scales are captured, from surface-layer turbulence to large- and very-large-scale outer-layer coherent motions. Spectrograms are used to support this argument, and also to illustrate how turbulent energy is distributed across wavelengths with elevation. Conditional averaging provides an ensemble-mean visualization of flow structures responsible for erosion `events'. Results indicate that surface-stress peaks are associated with the passage of inclined, high-momentum regions flanked by adjacent low-momentum regions. Fluid in the interfacial shear layers between these adjacent quasi-uniform momentum regions exhibits high streamwise and vertical vorticity.

  8. The power of event-driven analytics in Large Scale Data Processing

    SciTech Connect

    2011-02-24

    FeedZai is a software company specialized in creating high-­-throughput low-­-latency data processing solutions. FeedZai develops a product called "FeedZai Pulse" for continuous event-­-driven analytics that makes application development easier for end users. It automatically calculates key performance indicators and baselines, showing how current performance differ from previous history, creating timely business intelligence updated to the second. The tool does predictive analytics and trend analysis, displaying data on real-­-time web-­-based graphics. In 2010 FeedZai won the European EBN Smart Entrepreneurship Competition, in the Digital Models category, being considered one of the "top-­-20 smart companies in Europe". The main objective of this seminar/workshop is to explore the topic for large-­-scale data processing using Complex Event Processing and, in particular, the possible uses of Pulse in the scope of the data processing needs of CERN. Pulse is available as open-­-source and can be licensed both for non-­-commercial and commercial applications. FeedZai is interested in exploring possible synergies with CERN in high-­-volume low-­-latency data processing applications. The seminar will be structured in two sessions, the first one being aimed to expose the general scope of FeedZai's activities, and the second focused on Pulse itself: 10:00-11:00 FeedZai and Large Scale Data Processing Introduction to FeedZai FeedZai Pulse and Complex Event Processing Demonstration Use-Cases and Applications Conclusion and Q&A 11:00-11:15 Coffee break 11:15-12:30 FeedZai Pulse Under the Hood A First FeedZai Pulse Application PulseQL overview Defining KPIs and Baselines Conclusion and Q&A About the speakers Nuno Sebastião is the CEO of FeedZai. Having worked for many years for the European Space Agency (ESA), he was responsible the overall design and development of Satellite Simulation Infrastructure of the agency. Having left ESA to found FeedZai, Nuno is

  9. The power of event-driven analytics in Large Scale Data Processing

    ScienceCinema

    None

    2016-07-12

    FeedZai is a software company specialized in creating high-­-throughput low-­-latency data processing solutions. FeedZai develops a product called "FeedZai Pulse" for continuous event-­-driven analytics that makes application development easier for end users. It automatically calculates key performance indicators and baselines, showing how current performance differ from previous history, creating timely business intelligence updated to the second. The tool does predictive analytics and trend analysis, displaying data on real-­-time web-­-based graphics. In 2010 FeedZai won the European EBN Smart Entrepreneurship Competition, in the Digital Models category, being considered one of the "top-­-20 smart companies in Europe". The main objective of this seminar/workshop is to explore the topic for large-­-scale data processing using Complex Event Processing and, in particular, the possible uses of Pulse in the scope of the data processing needs of CERN. Pulse is available as open-­-source and can be licensed both for non-­-commercial and commercial applications. FeedZai is interested in exploring possible synergies with CERN in high-­-volume low-­-latency data processing applications. The seminar will be structured in two sessions, the first one being aimed to expose the general scope of FeedZai's activities, and the second focused on Pulse itself: 10:00-11:00 FeedZai and Large Scale Data Processing Introduction to FeedZai FeedZai Pulse and Complex Event Processing Demonstration Use-Cases and Applications Conclusion and Q&A 11:00-11:15 Coffee break 11:15-12:30 FeedZai Pulse Under the Hood A First FeedZai Pulse Application PulseQL overview Defining KPIs and Baselines Conclusion and Q&A About the speakers Nuno Sebastião is the CEO of FeedZai. Having worked for many years for the European Space Agency (ESA), he was responsible the overall design and development of Satellite Simulation Infrastructure of the agency. Having left ESA to found FeedZai, Nuno is

  10. Disturbance of aerobic metabolism accompanies neurobehavioral changes induced by nickel in mice.

    PubMed

    He, Min-Di; Xu, Shang-Cheng; Zhang, Xin; Wang, Yan; Xiong, Jia-Chuan; Zhang, Xiao; Lu, Yong-Hui; Zhang, Lei; Yu, Zheng-Ping; Zhou, Zhou

    2013-09-01

    The oral ingestion of soluble nickel compounds leads to neurological symptoms in humans. Deficiencies in aerobic metabolism induced by neurotoxic stimulus can cause an energy crisis in the brain that results in a variety of neurotoxic effects. In the present study, we focused on the aerobic metabolic states to investigate whether disturbance of aerobic metabolism was involved in nickel-induced neurological effects in mice. Mice were orally administered nickel chloride, and neurobehavioral performance was evaluated using the Morris water maze and open field tests at different time points. Aerobic metabolic states in the cerebral cortex were analyzed at the same time points at which neurobehavioral changes were evident. We found that nickel exposure caused deficits in both spatial memory and exploring activity in mice and that nickel was deposited in their cerebral cortex. Deficient aerobic metabolism manifested as decreased O2 consumption and ATP concentrations, lactate and NADH accumulation, and oxidative stress. Meanwhile, the activity of prototypical iron-sulfur clusters (ISCs) containing enzymes that are known to control aerobic metabolism, including complex I and aconitase, and the expression of ISC assembly scaffold protein (ISCU) were inhibited following nickel deposition. Overall, these data suggest that aerobic metabolic disturbances, which accompanied the neurobehavioral changes, may participate in nickel-induced neurologic effects. The inactivation of ISC containing metabolic enzymes may result in the disturbance of aerobic metabolism. A better understanding of how nickel impacts the energy metabolic processes may provide insight into the prevention of nickel neurotoxicity.

  11. Validation of the FAST skating protocol to predict aerobic power in ice hockey players.

    PubMed

    Petrella, Nicholas J; Montelpare, William J; Nystrom, Murray; Plyley, Michael; Faught, Brent E

    2007-08-01

    Few studies have reported a sport-specific protocol to measure the aerobic power of ice hockey players using a predictive process. The purpose of our study was to validate an ice hockey aerobic field test on players of varying ages, abilities, and levels. The Faught Aerobic Skating Test (FAST) uses an on-ice continuous skating protocol on a course measuring 160 feet (48.8 m) using a CD to pace the skater with a beep signal to cross the starting line at each end of the course. The FAST incorporates the principle of increasing workload at measured time intervals during a continuous skating exercise. Step-wise multiple regression modelling was used to determine the estimate of aerobic power. Participants completed a maximal aerobic power test using a modified Bruce incremental treadmill protocol, as well as the on-ice FAST. Normative data were collected on 406 ice hockey players (291 males, 115 females) ranging in age from 9 to 25 y. A regression to predict maximum aerobic power was developed using body mass (kg), height (m), age (y), and maximum completed lengths of the FAST as the significant predictors of skating aerobic power (adjusted R2 = 0.387, SEE = 7.25 mL.kg-1.min-1, p < 0.0001). These results support the application of the FAST in estimating aerobic power among male and female competitive ice hockey players between the ages of 9 and 25 years.

  12. Acclimation of aerobic-activated sludge degrading benzene derivatives and co-metabolic degradation activities of trichloroethylene by benzene derivative-grown aerobic sludge.

    PubMed

    Wang, Shizong; Yang, Qi; Bai, Zhiyong; Wang, Shidong; Wang, Yeyao; Nowak, Karolina M

    2015-01-01

    The acclimation of aerobic-activated sludge for degradation of benzene derivatives was investigated in batch experiments. Phenol, benzoic acid, toluene, aniline and chlorobenzene were concurrently added to five different bioreactors which contained the aerobic-activated sludge. After the acclimation process ended, the acclimated phenol-, benzoic acid-, toluene-, aniline- and chlorobenzene-grown aerobic-activated sludge were used to explore the co-metabolic degradation activities of trichloroethylene (TCE). Monod equation was employed to simulate the kinetics of co-metabolic degradation of TCE by benzene derivative-grown sludge. At the end of experiments, the mixed microbial communities grown under different conditions were identified. The results showed that the acclimation periods of microorganisms for different benzene derivatives varied. The maximum degradation rates of TCE for phenol-, benzoic acid-, toluene-, aniline- and chlorobenzene-grown aerobic sludge were 0.020, 0.017, 0.016, 0.0089 and 0.0047 mg g SS(-1) h(-1), respectively. The kinetic of TCE degradation in the absence of benzene derivative followed Monod equation well. Also, eight phyla were observed in the acclimated benzene derivative-grown aerobic sludge. Each of benzene derivative-grown aerobic sludge had different microbial community composition. This study can hopefully add new knowledge to the area of TCE co-metabolic by mixed microbial communities, and further the understanding on the function and applicability of aerobic-activated sludge.

  13. LSI/VLSI (Large Scale Integration/Very Large Scale Integration) ion implanted GaAs (Gallium Arsenide) IC processing

    NASA Astrophysics Data System (ADS)

    Zucca, R. R.; Kirkpatrick, C. G.; Asbeck, P. M.; Eisen, F. H.; Lee, C. P.

    1984-01-01

    This report covers a program designed to realize the full potential of GaAs integrated circuits by expanding and improving fabrication and material techniques. The main accomplishment of the program was the successful implementation of the fabrication of integrated circuits on 3-inch diameter GaAs wafers. In addition, this program covered many activities related to GaAs IC processing. These include: work on semi-insulating material growth and characterization, investigation of ion implantation techniques (work carried out at the California Institute of Technology); evaluation of device uniformity, and investigation of its controlling factors; investigation of metallization yield and reliability, and improvements of processing techniques resulting from this study; design and testing of a multiplier and programmable shift registers/pattern generators; evaluation of mask programmable logic arrays to meet ERADCOMs needs for high performance communication systems; investigation of the hardness of GaAs ICs to total dose and transient ionizing radiation, and modelling of MESFET devices (this work carried out at North Carolina State University).

  14. Hydrogeologic processes of large-scale tectonomagmatic complexes in Mongolia-southern Siberia and on Mars

    USGS Publications Warehouse

    Komatsu, G.; Dohm, J.M.; Hare, T.M.

    2004-01-01

    Large-scale tectonomagmatic complexes are common on Earth and Mars. Many of these complexes are created or at least influenced by mantle processes, including a wide array of plume types ranging from superplumes to mantle plumes. Among the most prominent complexes, the Mongolian plateau on Earth and the Tharsis bulge on Mars share remarkable similarities in terms of large domal uplifted areas, great rift canyon systems, and widespread volcanism on their surfaces. Water has also played an important role in the development of the two complexes. In general, atmospheric and surface water play a bigger role in the development of the present-day Mongolian plateau than for the Tharsis bulge, as evidenced by highly developed drainages and thick accumulation of sediments in the basins of the Baikal rift system. On the Tharsis bulge, however, water appears to have remained as ground ice except during periods of elevated magmatic activity. Glacial and periglacial processes are well documented for the Mongolian plateau and are also reported for parts of the Tharsis bulge. Ice-magma interactions, which are represented by the formation of subice volcanoes in parts of the Mongolian plateau region, have been reported for the Valles Marineris region of Mars. The complexes are also characterized by cataclysmic floods, but their triggering mechanism may differ: mainly ice-dam failures for the Mongolian plateau and outburst of groundwater for the Tharsis bulge, probably by magma-ice interactions, although ice-dam failures within the Valles Marineris region cannot be ruled out as a possible contributor. Comparative studies of the Mongolian plateau and Tharsis bulge provide excellent opportunities for understanding surface manifestations of plume-driven processes on terrestrial planets and how they interact with hydro-cryospheres. ?? 2004 Geological Society of America.

  15. In situ aerobic cometabolism of chlorinated solvents: a review.

    PubMed

    Frascari, Dario; Zanaroli, Giulio; Danko, Anthony S

    2015-01-01

    The possible approaches for in situ aerobic cometabolism of aquifers and vadose zones contaminated by chlorinated solvents are critically evaluated. Bioaugmentation of resting-cells previously grown in a fermenter and in-well addition of oxygen and growth substrate appear to be the most promising approaches for aquifer bioremediation. Other solutions involving the sparging of air lead to satisfactory pollutant removals, but must be integrated by the extraction and subsequent treatment of vapors to avoid the dispersion of volatile chlorinated solvents in the atmosphere. Cometabolic bioventing is the only possible approach for the aerobic cometabolic bioremediation of the vadose zone. The examined studies indicate that in situ aerobic cometabolism leads to the biodegradation of a wide range of chlorinated solvents within remediation times that vary between 1 and 17 months. Numerous studies include a simulation of the experimental field data. The modeling of the process attained a high reliability, and represents a crucial tool for the elaboration of field data obtained in pilot tests and for the design of the full-scale systems. Further research is needed to attain higher concentrations of chlorinated solvent degrading microbes and more reliable cost estimates. Lastly, a procedure for the design of full-scale in situ aerobic cometabolic bioremediation processes is proposed.

  16. Geoinformation web-system for processing and visualization of large archives of geo-referenced data

    NASA Astrophysics Data System (ADS)

    Gordov, E. P.; Okladnikov, I. G.; Titov, A. G.; Shulgina, T. M.

    2010-12-01

    Developed working model of information-computational system aimed at scientific research in area of climate change is presented. The system will allow processing and analysis of large archives of geophysical data obtained both from observations and modeling. Accumulated experience of developing information-computational web-systems providing computational processing and visualization of large archives of geo-referenced data was used during the implementation (Gordov et al, 2007; Okladnikov et al, 2008; Titov et al, 2009). Functional capabilities of the system comprise a set of procedures for mathematical and statistical analysis, processing and visualization of data. At present five archives of data are available for processing: 1st and 2nd editions of NCEP/NCAR Reanalysis, ECMWF ERA-40 Reanalysis, JMA/CRIEPI JRA-25 Reanalysis, and NOAA-CIRES XX Century Global Reanalysis Version I. To provide data processing functionality a computational modular kernel and class library providing data access for computational modules were developed. Currently a set of computational modules for climate change indices approved by WMO is available. Also a special module providing visualization of results and writing to Encapsulated Postscript, GeoTIFF and ESRI shape files was developed. As a technological basis for representation of cartographical information in Internet the GeoServer software conforming to OpenGIS standards is used. Integration of GIS-functionality with web-portal software to provide a basis for web-portal’s development as a part of geoinformation web-system is performed. Such geoinformation web-system is a next step in development of applied information-telecommunication systems offering to specialists from various scientific fields unique opportunities of performing reliable analysis of heterogeneous geophysical data using approved computational algorithms. It will allow a wide range of researchers to work with geophysical data without specific programming

  17. Integration of the stratigraphic aspects of very large sea-floor databases using information processing

    USGS Publications Warehouse

    Jenkins, Clinton N.; Flocks, J.; Kulp, M.; ,

    2006-01-01

    Information-processing methods are described that integrate the stratigraphic aspects of large and diverse collections of sea-floor sample data. They efficiently convert common types of sea-floor data into database and GIS (geographical information system) tables, visual core logs, stratigraphic fence diagrams and sophisticated stratigraphic statistics. The input data are held in structured documents, essentially written core logs that are particularly efficient to create from raw input datasets. Techniques are described that permit efficient construction of regional databases consisting of hundreds of cores. The sedimentological observations in each core are located by their downhole depths (metres below sea floor - mbsf) and also by a verbal term that describes the sample 'situation' - a special fraction of the sediment or position in the core. The main processing creates a separate output event for each instance of top, bottom and situation, assigning top-base mbsf values from numeric or, where possible, from word-based relative locational information such as 'core catcher' in reference to sampler device, and recovery or penetration length. The processing outputs represent the sub-bottom as a sparse matrix of over 20 sediment properties of interest, such as grain size, porosity and colour. They can be plotted in a range of core-log programs including an in-built facility that better suits the requirements of sea-floor data. Finally, a suite of stratigraphic statistics are computed, including volumetric grades, overburdens, thicknesses and degrees of layering. ?? The Geological Society of London 2006.

  18. Further development of chemical vapor deposition process for production of large diameter carbon-base monofilaments

    NASA Technical Reports Server (NTRS)

    Hough, R. L.; Richmond, R. D.

    1974-01-01

    The development of large diameter carbon-base monofilament in the 50 micron to 250 micron diameter range using the chemical vapor deposition process is described. The object of this program was to determine the critical process variables which control monofilament strength, monofilament modulus, and monofilament diameter. It was confirmed that wide scatter in the carbon substrate strength is primarily responsible for the scatter in the monofilament strength. It was also shown through etching experiments that defective substrate surface conditions which can induce low strength modular growth in the monofilament layers are best controlled by processing improvements during the synthesis of the substrate. Modulus was found to be linearily proportional to monofilament boron content. Filament modulus was increased to above 27.8MN/sq cm but only by a considerable increase in monofilament boron content to 60 wt. % or more. Monofilament diameter depended upon dwell time in the synthesis apparatus. A monofilament was prepared using these findings which had the combined properties of a mean U.T.S. of 398,000 N/sq cm, a modulus of 18.9 MN/sq cm (24,000,000 psi), and a diameter of 145 microns. Highest measured strength for this fiber was 451,000 N/sq cm (645,000 psi).

  19. A scale down process for the development of large volume cryopreservation☆

    PubMed Central

    Kilbride, Peter; Morris, G. John; Milne, Stuart; Fuller, Barry; Skepper, Jeremy; Selden, Clare

    2014-01-01

    The process of ice formation and propagation during cryopreservation impacts on the post-thaw outcome for a sample. Two processes, either network solidification or progressive solidification, can dominate the water–ice phase transition with network solidification typically present in small sample cryo-straws or cryo-vials. Progressive solidification is more often observed in larger volumes or environmental freezing. These different ice phase progressions could have a significant impact on cryopreservation in scale-up and larger volume cryo-banking protocols necessitating their study when considering cell therapy applications. This study determines the impact of these different processes on alginate encapsulated liver spheroids (ELS) as a model system during cryopreservation, and develops a method to replicate these differences in an economical manner. It was found in the current studies that progressive solidification resulted in fewer, but proportionally more viable cells 24 h post-thaw compared with network solidification. The differences between the groups diminished at later time points post-thaw as cells recovered the ability to undertake cell division, with no statistically significant differences seen by either 48 h or 72 h in recovery cultures. Thus progressive solidification itself should not prove a significant hurdle in the search for successful cryopreservation in large volumes. However, some small but significant differences were noted in total viable cell recoveries and functional assessments between samples cooled with either progressive or network solidification, and these require further investigation. PMID:25219980

  20. Subpixelic Measurement of Large 1D Displacements: Principle, Processing Algorithms, Performances and Software

    PubMed Central

    Guelpa, Valérian; Laurent, Guillaume J.; Sandoz, Patrick; Zea, July Galeano; Clévy, Cédric

    2014-01-01

    This paper presents a visual measurement method able to sense 1D rigid body displacements with very high resolutions, large ranges and high processing rates. Sub-pixelic resolution is obtained thanks to a structured pattern placed on the target. The pattern is made of twin periodic grids with slightly different periods. The periodic frames are suited for Fourier-like phase calculations—leading to high resolution—while the period difference allows the removal of phase ambiguity and thus a high range-to-resolution ratio. The paper presents the measurement principle as well as the processing algorithms (source files are provided as supplementary materials). The theoretical and experimental performances are also discussed. The processing time is around 3 μs for a line of 780 pixels, which means that the measurement rate is mostly limited by the image acquisition frame rate. A 3-σ repeatability of 5 nm is experimentally demonstrated which has to be compared with the 168 μm measurement range. PMID:24625736

  1. Subpixelic measurement of large 1D displacements: principle, processing algorithms, performances and software.

    PubMed

    Guelpa, Valérian; Laurent, Guillaume J; Sandoz, Patrick; Zea, July Galeano; Clévy, Cédric

    2014-03-12

    This paper presents a visual measurement method able to sense 1D rigid body displacements with very high resolutions, large ranges and high processing rates. Sub-pixelic resolution is obtained thanks to a structured pattern placed on the target. The pattern is made of twin periodic grids with slightly different periods. The periodic frames are suited for Fourier-like phase calculations-leading to high resolution-while the period difference allows the removal of phase ambiguity and thus a high range-to-resolution ratio. The paper presents the measurement principle as well as the processing algorithms (source files are provided as supplementary materials). The theoretical and experimental performances are also discussed. The processing time is around 3 µs for a line of 780 pixels, which means that the measurement rate is mostly limited by the image acquisition frame rate. A 3-σ repeatability of 5 nm is experimentally demonstrated which has to be compared with the 168 µm measurement range.

  2. In-database processing of a large collection of remote sensing data: applications and implementation

    NASA Astrophysics Data System (ADS)

    Kikhtenko, Vladimir; Mamash, Elena; Chubarov, Dmitri; Voronina, Polina

    2016-04-01

    Large archives of remote sensing data are now available to scientists, yet the need to work with individual satellite scenes or product files constrains studies that span a wide temporal range or spatial extent. The resources (storage capacity, computing power and network bandwidth) required for such studies are often beyond the capabilities of individual geoscientists. This problem has been tackled before in remote sensing research and inspired several information systems. Some of them such as NASA Giovanni [1] and Google Earth Engine have already proved their utility for science. Analysis tasks involving large volumes of numerical data are not unique to Earth Sciences. Recent advances in data science are enabled by the development of in-database processing engines that bring processing closer to storage, use declarative query languages to facilitate parallel scalability and provide high-level abstraction of the whole dataset. We build on the idea of bridging the gap between file archives containing remote sensing data and databases by integrating files into relational database as foreign data sources and performing analytical processing inside the database engine. Thereby higher level query language can efficiently address problems of arbitrary size: from accessing the data associated with a specific pixel or a grid cell to complex aggregation over spatial or temporal extents over a large number of individual data files. This approach was implemented using PostgreSQL for a Siberian regional archive of satellite data products holding hundreds of terabytes of measurements from multiple sensors and missions taken over a decade-long span. While preserving the original storage layout and therefore compatibility with existing applications the in-database processing engine provides a toolkit for provisioning remote sensing data in scientific workflows and applications. The use of SQL - a widely used higher level declarative query language - simplifies interoperability

  3. Large-Scale Simulation of a Process for Cataloguing Small Orbital Debris

    NASA Astrophysics Data System (ADS)

    Phillion, D.; Pertica, A.; Fasenfest, B.; Horsley, M.; de Vries, W.; Springer, H.; Jefferson, D.; Olivier, S.; Hill, K.; Sabol, C.

    2010-09-01

    We demonstrate a methodology for establishing orbits for the abundant, un-catalogued, yet dangerous, small orbital debris that will become observable with planned improvements to the Space Fence. Although roughly 15,000 orbital objects are present in the SSN catalog, it is believed that at least 200,000 objects that are massive enough to cause significant damage are in Earth orbit. With improvements to the Space Fence, LEO debris down to 5 cm in size may become observable. The additional hundreds of thousands of observations a day of mostly un-catalogued objects will present a significant data processing challenge. Of particular concern are the large numbers of observations that are uncorrelated either to a known object or to a single object. To deal with the large-scale uncorrelated track (UCT) problem, we have ported the Covariance-Based Track Algorithm (CBTA) into the supercomputer-based Testbed Environment for Space Situational Awareness (TESSA) in order to perform simulations at scale. CBTA bins UCTs for which initial orbits and initial covariance matrices could be determined back to a common epoch and then uses a statistical measure to see if they correlate given the state vectors and covariance matrices at that common time. If they do, the observations from the two tracks are combined and orbit determination (OD) is used to attempt to fit an orbit to the combined tracks. If OD converges, a new UCT hypothesis is created and the state and covariance of that hypothesis is saved with the other pre-existing UCTs. If a certain number of tracks are successfully combined then they are used to create a new catalog object. Old UCTs are weeded out of the pool of hypotheses when they become obsolete, or when at least some of the observations are used to create a new catalog object. For the simulation, we developed a Radar detection model simulating the performance of a notional new Space Fence. We propagated thousands of objects over a several day period creating a

  4. Lower limb loading in step aerobic dance.

    PubMed

    Wu, H-W; Hsieh, H-M; Chang, Y-W; Wang, L-H

    2012-11-01

    Participation in aerobic dance is associated with a number of lower extremity injuries, and abnormal joint loading seems to be a factor in these. However, information on joint loading is limited. The purpose of this study was to investigate the kinetics of the lower extremity in step aerobic dance and to compare the differences of high-impact and low-impact step aerobic dance in 4 aerobic movements (mambo, kick, L step and leg curl). 18 subjects were recruited for this study. High-impact aerobic dance requires a significantly greater range of motion, joint force and joint moment than low-impact step aerobic dance. The peak joint forces and moments in high-impact step aerobic dance were found to be 1.4 times higher than in low-impact step aerobic dance. Understanding the nature of joint loading may help choreographers develop dance combinations that are less injury-prone. Furthermore, increased knowledge about joint loading may be helpful in lowering the risk of injuries in aerobic dance instructors and students.

  5. The Physical, Geochemical and Microbial Conditions and Processes in the Hyporheic Zone of a Large Tidally Influenced River: The Fraser River, British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Bianchin, M.; Roschinski, T.; Ross, K.; Leslie, S.; William, M.; Beckie, R.

    2006-12-01

    The objective of this research is to investigate the physical, chemical and biological conditions and processes that occur in the hyporheic zone of the lower Fraser River, British Columbia. The large flows of between 2000 and 10000 cubic meters per second, the 10 15 m deep, 250 m wide channel, the 1 m tidal fluctuations, the localized scour and redeposition of sediments during freshet and the strong geochemical contrast between groundwater and surface water distinguish this investigation from studies on smaller channels and streams and required the development of novel characterization tools and strategies. The geochemistry of water samples collected with a push-in profiler, bulk electrical conductivity (EC) measurements collected with a push-in tool and hydraulic head measurements indicate that groundwater principally discharges into the river approximately 100 m offshore in a 10 m wide band. River water and groundwater mix to a maximum depth of between 0.75 and 1.5 m. While hydraulic heads show strong tidal reversals, bulk EC profiles show only moderate changes during the tidal cycle. It was hypothesized that high iron (10's mg/L of Fe(II)) in reduced groundwater would precipitate from solution as secondary iron-oxide phases in the zone where groundwater mixes with aerobic river water. Sediments were collected with a freeze-shoe corer and depth profiles through the hyporheic zone and into the underlying aquifer were analyzed by selective extractions. The 15-30 mg/g of total extractable iron in both the aquifer and hyporheic zone is relatively high. The lack of noticeable iron accumulation in the hyporheic zone may indicate that iron precipitates on shallow sediments that are subsequently scoured from the river bed during freshet. Microbial DNA from sediments was analyzed using denaturing gradient gel electrophoresis and showed a relatively diverse community structure but an overall low biomass.

  6. Plasma processing of large curved surfaces for superconducting rf cavity modification

    NASA Astrophysics Data System (ADS)

    Upadhyay, J.; Im, Do; Popović, S.; Valente-Feliciano, A.-M.; Phillips, L.; Vušković, L.

    2014-12-01

    Plasma-based surface modification of niobium is a promising alternative to wet etching of superconducting radio frequency (SRF) cavities. We have demonstrated surface layer removal in an asymmetric nonplanar geometry, using a simple cylindrical cavity. The etching rate is highly correlated with the shape of the inner electrode, radio-frequency (rf) circuit elements, gas pressure, rf power, chlorine concentration in the Cl2/Ar gas mixtures, residence time of reactive species, and temperature of the cavity. Using variable radius cylindrical electrodes, large-surface ring-shaped samples, and dc bias in the external circuit, we have measured substantial average etching rates and outlined the possibility of optimizing plasma properties with respect to maximum surface processing effect.

  7. FUNDAMENTAL STUDIES OF IGNITION PROCESSES IN LARGE NATURAL GAS ENGINES USING LASER SPARK IGNITION

    SciTech Connect

    Azer Yalin; Morgan Defoort; Bryan Willson

    2005-01-01

    The current report details project progress made during the first quarterly reporting period of the DOE sponsored project ''Fundamental studies of ignition processes in large natural gas engines using laser spark ignition''. The goal of the overall research effort is to develop a laser ignition system for natural gas engines, with a particular focus on using fiber optic delivery methods. In this report we present our successful demonstration of spark formation using fiber delivery made possible though the use of novel coated hollow fibers. We present results of (high power) experimental characterizations of light propagation using hollow fibers using both a high power research grade laser as well as a more compact laser. Finally, we present initial designs of the system we are developing for future on-engine testing using the hollow fibers.

  8. Processing large sensor data sets for safeguards : the knowledge generation system.

    SciTech Connect

    Thomas, Maikel A.; Smartt, Heidi Anne; Matthews, Robert F.

    2012-04-01

    Modern nuclear facilities, such as reprocessing plants, present inspectors with significant challenges due in part to the sheer amount of equipment that must be safeguarded. The Sandia-developed and patented Knowledge Generation system was designed to automatically analyze large amounts of safeguards data to identify anomalous events of interest by comparing sensor readings with those expected from a process of interest and operator declarations. This paper describes a demonstration of the Knowledge Generation system using simulated accountability tank sensor data to represent part of a reprocessing plant. The demonstration indicated that Knowledge Generation has the potential to address several problems critical to the future of safeguards. It could be extended to facilitate remote inspections and trigger random inspections. Knowledge Generation could analyze data to establish trust hierarchies, to facilitate safeguards use of operator-owned sensors.

  9. A Natural Language Processing Tool for Large-Scale Data Extraction from Echocardiography Reports

    PubMed Central

    Jonnalagadda, Siddhartha R.

    2016-01-01

    Large volumes of data are continuously generated from clinical notes and diagnostic studies catalogued in electronic health records (EHRs). Echocardiography is one of the most commonly ordered diagnostic tests in cardiology. This study sought to explore the feasibility and reliability of using natural language processing (NLP) for large-scale and targeted extraction of multiple data elements from echocardiography reports. An NLP tool, EchoInfer, was developed to automatically extract data pertaining to cardiovascular structure and function from heterogeneously formatted echocardiographic data sources. EchoInfer was applied to echocardiography reports (2004 to 2013) available from 3 different on-going clinical research projects. EchoInfer analyzed 15,116 echocardiography reports from 1684 patients, and extracted 59 quantitative and 21 qualitative data elements per report. EchoInfer achieved a precision of 94.06%, a recall of 92.21%, and an F1-score of 93.12% across all 80 data elements in 50 reports. Physician review of 400 reports demonstrated that EchoInfer achieved a recall of 92–99.9% and a precision of >97% in four data elements, including three quantitative and one qualitative data element. Failure of EchoInfer to correctly identify or reject reported parameters was primarily related to non-standardized reporting of echocardiography data. EchoInfer provides a powerful and reliable NLP-based approach for the large-scale, targeted extraction of information from heterogeneous data sources. The use of EchoInfer may have implications for the clinical management and research analysis of patients undergoing echocardiographic evaluation. PMID:27124000

  10. Magnesium carbonate precipitate strengthened aerobic granules.

    PubMed

    Lee, Duu-Jong; Chen, Yu-You

    2015-05-01

    Aerobic granules were precipitated internally with magnesium carbonate to enhance their structural stability under shear. The strengthened granules were tested in continuous-flow reactors for 220 days at organic loadings of 6-39 kg/m(3)/day, hydraulic retention times of 0.44-19 h, and temperatures of 10 or 28°C. The carbonate salt had markedly improved the granule strength without significant changes in granule morphology or microbial communities (with persistent strains Streptomyces sp., Rhizobium sp., Brevundimonas sp., and Nitratireductor sp.), or sacrifice in biological activity for organic degradation. MgCO3 precipitated granules could be used in continuous-flow reactor for wastewater treatment at low cost and with easy processing efforts.

  11. Brain aerobic glycolysis and motor adaptation learning

    PubMed Central

    Shannon, Benjamin J.; Vaishnavi, Sanjeev Neil; Vlassenko, Andrei G.; Shimony, Joshua S.; Rutlin, Jerrel; Raichle, Marcus E.

    2016-01-01

    Ten percent to 15% of glucose used by the brain is metabolized nonoxidatively despite adequate tissue oxygenation, a process termed aerobic glycolysis (AG). Because of the known role of glycolysis in biosynthesis, we tested whether learning-induced synaptic plasticity would lead to regionally appropriate, learning-dependent changes in AG. Functional MRI (fMRI) before, during, and after performance of a visual–motor adaptation task demonstrated that left Brodmann area 44 (BA44) played a key role in adaptation, with learning-related changes to activity during the task and altered resting-state, functional connectivity after the task. PET scans before and after task performance indicated a sustained increase in AG in left BA 44 accompanied by decreased oxygen consumption. Intersubject variability in behavioral adaptation rate correlated strongly with changes in AG in this region, as well as functional connectivity, which is consistent with a role for AG in synaptic plasticity. PMID:27217563

  12. Biology of Moderately Halophilic Aerobic Bacteria

    PubMed Central

    Ventosa, Antonio; Nieto, Joaquín J.; Oren, Aharon

    1998-01-01

    The moderately halophilic heterotrophic aerobic bacteria form a diverse group of microorganisms. The property of halophilism is widespread within the bacterial domain. Bacterial halophiles are abundant in environments such as salt lakes, saline soils, and salted food products. Most species keep their intracellular ionic concentrations at low levels while synthesizing or accumulating organic solutes to provide osmotic equilibrium of the cytoplasm with the surrounding medium. Complex mechanisms of adjustment of the intracellular environments and the properties of the cytoplasmic membrane enable rapid adaptation to changes in the salt concentration of the environment. Approaches to the study of genetic processes have recently been developed for several moderate halophiles, opening the way toward an understanding of haloadaptation at the molecular level. The new information obtained is also expected to contribute to the development of novel biotechnological uses for these organisms. PMID:9618450

  13. ParaText : scalable solutions for processing and searching very large document collections : final LDRD report.

    SciTech Connect

    Crossno, Patricia Joyce; Dunlavy, Daniel M.; Stanton, Eric T.; Shead, Timothy M.

    2010-09-01

    This report is a summary of the accomplishments of the 'Scalable Solutions for Processing and Searching Very Large Document Collections' LDRD, which ran from FY08 through FY10. Our goal was to investigate scalable text analysis; specifically, methods for information retrieval and visualization that could scale to extremely large document collections. Towards that end, we designed, implemented, and demonstrated a scalable framework for text analysis - ParaText - as a major project deliverable. Further, we demonstrated the benefits of using visual analysis in text analysis algorithm development, improved performance of heterogeneous ensemble models in data classification problems, and the advantages of information theoretic methods in user analysis and interpretation in cross language information retrieval. The project involved 5 members of the technical staff and 3 summer interns (including one who worked two summers). It resulted in a total of 14 publications, 3 new software libraries (2 open source and 1 internal to Sandia), several new end-user software applications, and over 20 presentations. Several follow-on projects have already begun or will start in FY11, with additional projects currently in proposal.

  14. Gaining insight into river ecosystem processes from a large-scale flow experiment

    NASA Astrophysics Data System (ADS)

    Harrison, L.; Pike, A.; Boughton, D. A.

    2015-12-01

    In rivers throughout the world, anthropogenic impacts related to large dams have altered or eliminated the habitat necessary for many aquatic organisms. Flow experiments, both planned and unplanned, provide unique opportunities to evaluate the extent to which alternative dam operations can provide downstream ecological benefits. Here we use an unanticipated, reservoir release on the Santa Ynez River in southern California to investigate how a large flood influenced river ecosystem processes. We directly measured the flood-induced, topographic changes over 80 km of the river and floodplain using two high-resolution field and remote sensing data sets that bracketed the flood event. DEM-differencing of the pre- and post-flood topography was used to calculate shifts in the active channel planform and the net volumetric fluxes in gravel storage along the channel and floodplain. LiDAR and image-based habitat mapping was conducted to quantify the proportion of different habitat units before and after the flood. Large-scale geomorphic changes were observed as a result of the flood, including lateral migration of the river channel, gravel bar formation and the development of off-channel chute habitat. Spatial patterns of gravel storage changed with distance from the dam, with the upper 20 km experiencing a net sediment deficit and the lower 60 km undergoing net deposition. The longitudinal trends in gravel transport and storage reflect differences in the channel gradient, valley confinement and density of floodplain vegetation. We found that the flood nearly doubled the extent of pool habitat, primarily by converting runs to pools and by incising new pools adjacent to valley walls and terraces. The increase in the number of pools was predicted to have positive impacts on steelhead habitat, by providing a broader range of water depths and micro-habitats utilized by different age classes. Results from this study highlight the value of using flow pulses as opportunities to

  15. Large Eddy Simulation of Transient Flow, Solidification, and Particle Transport Processes in Continuous-Casting Mold

    NASA Astrophysics Data System (ADS)

    Liu, Zhongqiu; Li, Linmin; Li, Baokuan; Jiang, Maofa

    2014-07-01

    The current study developed a coupled computational model to simulate the transient fluid flow, solidification, and particle transport processes in a slab continuous-casting mold. Transient flow of molten steel in the mold is calculated using the large eddy simulation. An enthalpy-porosity approach is used for the analysis of solidification processes. The transport of bubble and non-metallic inclusion inside the liquid pool is calculated using the Lagrangian approach based on the transient flow field. A criterion of particle entrapment in the solidified shell is developed using the user-defined functions of FLUENT software (ANSYS, Inc., Canonsburg, PA). The predicted results of this model are compared with the measurements of the ultrasonic testing of the rolled steel plates and the water model experiments. The transient asymmetrical flow pattern inside the liquid pool exhibits quite satisfactory agreement with the corresponding measurements. The predicted complex instantaneous velocity field is composed of various small recirculation zones and multiple vortices. The transport of particles inside the liquid pool and the entrapment of particles in the solidified shell are not symmetric. The Magnus force can reduce the entrapment ratio of particles in the solidified shell, especially for smaller particles, but the effect is not obvious. The Marangoni force can play an important role in controlling the motion of particles, which increases the entrapment ratio of particles in the solidified shell obviously.

  16. Zinc nanowires synthesized on a large scale by a simple carbothermal process

    NASA Astrophysics Data System (ADS)

    Araújo, Jacyra V. D. S.; Ferreira, Rafael V.; Yoshida, Maria I.; Pasa, Vânya M. D.

    2009-09-01

    Metallic Zn nanowires have been synthesized by a new carbothermal reduction route in which ZnO and Eucalyptus sp. tar pitch were used as source materials. This simple practical procedure was capable of producing Zn nanowires in large quantities without reoxidation. This process was carried out in inert atmosphere, without vacuum or catalyst, at temperatures (800-900 °C) lower than those required in the carbothermal reduction of ZnO with graphite. A comparative study was performed using graphite that is traditionally used as a ZnO reducer, under the same experimental conditions, however, no reaction was observed. The new process involves the pyrolysis of biopitch to obtain a highly reactive coke and the reduction of ZnO with the release of Zn (v) for the growth of Zn (s) nanowires. The resulting Zn nanowires were characterized by X-ray diffractometry, energy-dispersive spectroscopy and scanning electron microscopy. Differential thermal analysis and thermogravimetric analysis coupled with infrared analysis techniques were used in an effort to understand the underlying mechanism and establish the best ratio biopitch/ZnO to be used. This paper presents the characterization of the as-synthesized nanowires and discusses the main reactions involved in their production.

  17. Relative importance of breakage and decay as processes depleting large wood from streams

    NASA Astrophysics Data System (ADS)

    Merten, Eric C.; Vaz, Pedro G.; Decker-Fritz, Jo A.; Finlay, Jacques C.; Stefan, Heinz G.

    2013-05-01

    Large wood pieces affect virtually every physical, chemical, and biological process in fluvial systems, including hydraulics, transport of materials, algal biomass accrual, nutrient uptake, and trophic interactions. The processes that deplete wood are thus of broad importance to stream ecosystems. We assessed the relative contributions for breakage-induced mobilization (where pieces are more prone to transport as a result of breakage into shorter parts) and gradual biochemical decay to wood depletion rates in a field study on 12 northern Minnesota, USA, streams. Wood pieces > 0.05 m in diameter for a portion > 1 m in length were individually tagged (n = 651), measured, and remeasured a year later. Pieces showed significant reductions in density and branching complexity (i.e., branches and twigs) and 22% of pieces broke (i.e., lost 10% or more of length). Processes related to breakage and decay were examined using Bayesian structural equation modeling and multiple regression. Breakage was more likely for pieces that were thin in diameter, long, deeply submerged, braced, buried, and traveled long distances. Pieces lost more density if they were initially dense, traveled a long distance, were not deeply submerged, lacked bark, were thin in diameter, were steeply pitched, were long, and were not buried. Pieces lost more branching complexity if they were complex with little gap between them and the streambed. Actual mass losses related to breakage and decay were 7.3% and 1.9% (respectively), both less than the 36% observed for total fluvial export. In contrast to the associations of breakage and decay with structural properties of the wood pieces and their position, hydraulic and geomorphic variables (stream power, slope, velocity, width) had little effect.

  18. Validation of New Process Models for Large Injection-Molded Long-Fiber Thermoplastic Composite Structures

    SciTech Connect

    Nguyen, Ba Nghiep; Jin, Xiaoshi; Wang, Jin; Kunc, Vlastimil; Tucker III, Charles L.

    2012-02-23

    This report describes the work conducted under the CRADA Nr. PNNL/304 between Battelle PNNL and Autodesk whose objective is to validate the new process models developed under the previous CRADA for large injection-molded LFT composite structures. To this end, the ARD-RSC and fiber length attrition models implemented in the 2013 research version of Moldflow was used to simulate the injection molding of 600-mm x 600-mm x 3-mm plaques from 40% glass/polypropylene (Dow Chemical DLGF9411.00) and 40% glass/polyamide 6,6 (DuPont Zytel 75LG40HSL BK031) materials. The injection molding was performed by Injection Technologies, Inc. at Windsor, Ontario (under a subcontract by Oak Ridge National Laboratory, ORNL) using the mold offered by the Automotive Composite Consortium (ACC). Two fill speeds under the same back pressure were used to produce plaques under slow-fill and fast-fill conditions. Also, two gating options were used to achieve the following desired flow patterns: flows in edge-gated plaques and in center-gated plaques. After molding, ORNL performed measurements of fiber orientation and length distributions for process model validations. The structure of this report is as follows. After the Introduction (Section 1), Section 2 provides a summary of the ARD-RSC and fiber length attrition models. A summary of model implementations in the latest research version of Moldflow is given in Section 3. Section 4 provides the key processing conditions and parameters for molding of the ACC plaques. The validations of the ARD-RSC and fiber length attrition models are presented and discussed in Section 5. The conclusions will be drawn in Section 6.

  19. Kinetics of aerobic cometabolic biodegradation of chlorinated and brominated aliphatic hydrocarbons: A review.

    PubMed

    Jesus, João; Frascari, Dario; Pozdniakova, Tatiana; Danko, Anthony S

    2016-05-15

    This review analyses kinetic studies of aerobic cometabolism (AC) of halogenated aliphatic hydrocarbons (HAHs) from 2001-2015 in order to (i) compare the different kinetic models proposed, (ii) analyse the estimated model parameters with a focus on novel HAHs and the identification of general trends, and (iii) identify further research needs. The results of this analysis show that aerobic cometabolism can degrade a wide range of HAHs, including HAHs that were not previously tested such as chlorinated propanes, highly chlorinated ethanes and brominated methanes and ethanes. The degree of chlorine mineralization was very high for the chlorinated HAHs. Bromine mineralization was not determined for studies with brominated aliphatics. The examined research period led to the identification of novel growth substrates of potentially high interest. Decreasing performance of aerobic cometabolism were found with increasing chlorination, indicating the high potential of aerobic cometabolism in the presence of medium- and low-halogenated HAHs. Further research is needed for the AC of brominated aliphatic hydrocarbons, the potential for biofilm aerobic cometabolism processes, HAH-HAH mutual inhibition and the identification of the enzymes responsible for each aerobic cometabolism process. Lastly, some indications for a possible standardization of future kinetic studies of HAH aerobic cometabolism are provided.

  20. Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer.

    PubMed

    Han, Jun; Meng, Qingyang; Xi, Qiulei; Zhang, Yongxian; Zhuang, Qiulin; Han, Yusong; Jiang, Yi; Ding, Qiurong; Wu, Guohao

    2016-01-01

    Chronic inflammation is a well-known etiological factor for colorectal cancer (CRC) and cancer cells are known to preferentially metabolize glucose through aerobic glycolysis. However, the connection between chronic inflammation and aerobic glycolysis in the development of CRC is largely unexplored. The present study investigated whether interleukin-6 (IL-6), a pro-inflammatory cytokine, promotes the development of CRC by regulating the aerobic glycolysis and the underlying molecular mechanisms. In colitis-associated CRC mouse, anti-IL-6 receptor antibody treatment reduced the incidence of CRC and decreased the expression of key genes in aerobic glycolysis, whereas the plasma concentrations of glucose and lactate were not affected. Consistently, IL-6 treatment stimulated aerobic glycolysis, upregulated key genes in aerobic glycolysis and promoted cell proliferation and migration in SW480 and SW1116 CRC cells. 6-phoshofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) was the most downregulated gene by anti-IL-6 receptor antibody in colorectal adenoma tissues. Further analysis in human samples revealed overexpression of PFKFB3 in colorectal adenoma and adenocarcinoma tissues, which was also associated with lymph node metastasis, intravascular cancer embolus and TNM stage. In addition, the effect of IL-6 on CRC cells can be abolished by knocking down PRKFB3 through siRNA transfection. Our data suggest that chronic inflammation promotes the development of CRC by stimulating aerobic glycolysis and IL-6 is functioning, at least partly, through regulating PFKFB3 at early stage of CRC.

  1. Torque measurements reveal large process differences between materials during high solid enzymatic hydrolysis of pretreated lignocellulose

    PubMed Central

    2012-01-01

    Background A common trend in the research on 2nd generation bioethanol is the focus on intensifying the process and increasing the concentration of water insoluble solids (WIS) throughout the process. However, increasing the WIS content is not without problems. For example, the viscosity of pretreated lignocellulosic materials is known to increase drastically with increasing WIS content. Further, at elevated viscosities, problems arise related to poor mixing of the material, such as poor distribution of the enzymes and/or difficulties with temperature and pH control, which results in possible yield reduction. Achieving good mixing is unfortunately not without cost, since the power requirements needed to operate the impeller at high viscosities can be substantial. This highly important scale-up problem can easily be overlooked. Results In this work, we monitor the impeller torque (and hence power input) in a stirred tank reactor throughout high solid enzymatic hydrolysis (< 20% WIS) of steam-pretreated Arundo donax and spruce. Two different process modes were evaluated, where either the impeller speed or the impeller power input was kept constant. Results from hydrolysis experiments at a fixed impeller speed of 10 rpm show that a very rapid decrease in impeller torque is experienced during hydrolysis of pretreated arundo (i.e. it loses its fiber network strength), whereas the fiber strength is retained for a longer time within the spruce material. This translates into a relatively low, rather WIS independent, energy input for arundo whereas the stirring power demand for spruce is substantially larger and quite WIS dependent. By operating the impeller at a constant power input (instead of a constant impeller speed) it is shown that power input greatly affects the glucose yield of pretreated spruce whereas the hydrolysis of arundo seems unaffected. Conclusions The results clearly highlight the large differences between the arundo and spruce materials, both in terms of

  2. Investigating convective transport processes and large scale stratospheric dynamics with ICON-ART

    NASA Astrophysics Data System (ADS)

    Stassen, Christian; Ruhnke, Roland; Schröter, Jennifer; Daniel, Rieger; Bischoff-Gauss, Ingeborg; Vogel, Heike; Vogel, Bernhard

    2015-04-01

    We have extended the global ICON (ICOsahedral Nonhydrostatic) modelling framework. ICON is a joint development by the German Weather Service (DWD) and the Max-Planck-Institute for Meteorology (MPI-M). We added modules for gas-phase chemistry and aerosol dynamics (ART, Aerosols and Reactive Trace gases) [1]. ICON allows a regional grid refinement with two-way interactions between the different horizontal grids. It is used by DWD for numerical weather predictions and will be used by MPI-M for climate projections [2]. The extended modelling framework ICON-ART is developed in an analogous way to its predecessors COSMO-ART [3], so that aerosol and chemical composition feedbacks can be considered in a comprehensive way. Up to now, ICON-ART accounts for volcanic ash tracers, radioactive tracers, sea salt and mineral dust aerosols. Additionally, several gaseous tracers have been introduced. For the dynamics (transport and diffusion) of aerosol and gaseous tracers, the original ICON tracer framework is used. For the model physics, numerical time integration follows a process splitting approach separating physical processes. Each process is called independently via an interface module. Currently, the processes of emission, dry and wet deposition, sedimentation, and first order chemical reactions are included. We will present a simulation of the transport of ozone depleting short-lived trace gases from the surface into the stratosphere as well as of long-lived tracers. The simulated tracer distributions are used to investigate the ability of ICON-ART to simulate convective vertical transport in the troposphere as well as of large-scale stratospheric dynamics. [1] Rieger, D., et al. (2014), ICON-ART - A new online-coupled model system from the global to regional scale, submitted to Geosci. Model Dev. [2] Zängl, G., et al. (2014), The ICON (ICOsahedral Non-hydrostatic) modelling framework of DWD MPI-M: Description of the non-hydrostatic dynamical core. Q.J.R. Meteorol. Soc

  3. Skeletal Muscle Hypertrophy after Aerobic Exercise Training

    PubMed Central

    Konopka, Adam R.; Harber, Matthew P.

    2014-01-01

    Current dogma suggests aerobic exercise training has minimal effect on skeletal muscle size. We and others have demonstrated that aerobic exercise acutely and chronically alters protein metabolism and induces skeletal muscle hypertrophy. These findings promote an antithesis to the status quo by providing novel perspective on skeletal muscle mass regulation and insight into exercise-countermeasures for populations prone to muscle loss. PMID:24508740

  4. Aerobic Fitness for the Moderately Retarded.

    ERIC Educational Resources Information Center

    Bauer, Dan

    1981-01-01

    Intended for physical education teachers, the booklet offers ideas for incorporating aerobic conditioning into programs for moderately mentally retarded students. An explanation of aerobic fitness and its benefits is followed by information on initiating a fitness program with evaluation of height, weight, body fat, resting heart rate, and…

  5. Aerobic Dancing--A Rhythmic Sport.

    ERIC Educational Resources Information Center

    Sorensen, Jacki

    Fitness programs now and in the future must offer built-in cardiovascular conditioning, variety, novelty, and change to meet the physical, mental, and emotional needs of our society. Aerobic dancing (dancing designed to train and strengthen the heart, lungs, and vascular system) is one of the first indoor group Aerobic exercise programs designed…

  6. Observational and Model Studies of Large-Scale Mixing Processes in the Stratosphere

    NASA Technical Reports Server (NTRS)

    Bowman, Kenneth P.

    1997-01-01

    The following is the final technical report for grant NAGW-3442, 'Observational and Model Studies of Large-Scale Mixing Processes in the Stratosphere'. Research efforts in the first year concentrated on transport and mixing processes in the polar vortices. Three papers on mixing in the Antarctic were published. The first was a numerical modeling study of wavebreaking and mixing and their relationship to the period of observed stratospheric waves (Bowman). The second paper presented evidence from TOMS for wavebreaking in the Antarctic (Bowman and Mangus 1993). The third paper used Lagrangian trajectory calculations from analyzed winds to show that there is very little transport into the Antarctic polar vortex prior to the vortex breakdown (Bowman). Mixing is significantly greater at lower levels. This research helped to confirm theoretical arguments for vortex isolation and data from the Antarctic field experiments that were interpreted as indicating isolation. A Ph.D. student, Steve Dahlberg, used the trajectory approach to investigate mixing and transport in the Arctic. While the Arctic vortex is much more disturbed than the Antarctic, there still appears to be relatively little transport across the vortex boundary at 450 K prior to the vortex breakdown. The primary reason for the absence of an ozone hole in the Arctic is the earlier warming and breakdown of the vortex compared to the Antarctic, not replenishment of ozone by greater transport. Two papers describing these results have appeared (Dahlberg and Bowman; Dahlberg and Bowman). Steve Dahlberg completed his Ph.D. thesis (Dahlberg and Bowman) and is now teaching in the Physics Department at Concordia College. We also prepared an analysis of the QBO in SBUV ozone data (Hollandsworth et al.). A numerical study in collaboration with Dr. Ping Chen investigated mixing by barotropic instability, which is the probable origin of the 4-day wave in the upper stratosphere (Bowman and Chen). The important result from

  7. Quantifying the process-product relationship in the large sandy Rio Paraná

    NASA Astrophysics Data System (ADS)

    Ashworth, P. J.; Amsler, M.; Best, J.; Orfeo, O.; Parsons, D.; Reesink, A.; Sambrook Smith, G.; Szupiany, R.

    2010-12-01

    Whilst recent technological advances have enabled the measurement and modelling of alluvial processes and dynamics, arguably less progress has been made in relating the morphodynamics to the resulting sedimentary alluvial architecture. This paper will present data from the sandy, multi-channel Rio Paraná, Argentina, where the evolution of km-scale braid-bars is being related directly to the resultant sedimentary deposits. Bathymetric data from the Rio Paraná was collected from survey vessels using single and multi-beam echo-sounding located by RTK dGPS. Flow data at various flow stages was also collected using acoustic Doppler current profiler (aDcp) surveys at key cross-sections. The subsurface architecture was characterised at low flow using 10s of km of Ground Penetrating Radar (GPR), and ground-truthed using suction coring. GPR achieved penetration depths down to 10 m and reflections allowed quantification of the radar facies to within +/- 0.2 m in the vertical. These techniques, and the logistical considerations required in their deployment and integration in the field, will be discussed. The paper will also highlight how an integrated morphodynamic and GPR survey programme in one of the world’s largest rivers can provide high-resolution data that: (i) links blocks of sedimentation to specific, identifiable channel processes, (ii) quantifies the vertical and horizontal distribution of sedimentary facies in large rivers, and relates this to the temporal evolution of the channel, and (iii) is at sub-seismic resolution and therefore suitable for reservoir-scale lithofacies modelling.

  8. Lightning Processes And Dynamics Of Large Scale Optical Emissions In Long Delayed Sprites

    NASA Astrophysics Data System (ADS)

    Li, J.; Cummer, S. A.; Lyons, W. A.; Nelson, T. E.; Hu, W.

    2006-12-01

    Simultaneous measurements of high altitude optical emissions and the magnetic field produced by sprite-associated lightning discharges enable a close examination of the link between low altitude lightning process and high altitude sprite process. In this work, we report results of the coordinated analysis of high speed (1000--10000 frames per second) sprite video and wideband (0.1 Hz to 30 kHz) magnetic field measurements made simultaneously at the Yucca Ridge Field Station and Duke University during the June through August 2005 campaign period. We investigate the relationship of lightning charge transfer characteristics and long delayed (>30 ms) sprites after the lightning return stroke. These long delayed sprites initiated after a total vertical charge moment change from a few thousand C km to more than ten thousand C km. Continuing currents provide about 50% to 90% of this total charge transfer depending on the sprite delayed time and amplitude of continuing current. Our data also show that intense continuing current bigger than a few kA plays an important role in sprites whose primary optical emissions last unusually long (>30 ms). On one observation night (4 July 2005), a large mesoscale convective system produced many sprites that were part of complex transient luminous event (TLE) sequences that included optical emission elements that appear well after any return stroke and initiate at apparently relatively low altitudes (~ 50 km). These low initiation altitude sprite events are typically associated with intense continuing currents and total charge moment changes of 4000 C km or more. With the estimated lightning source current moment waveform, we also employ a 2-D FDTD model to numerically simulate the electric field at different altitudes and compare it with the breakdown field. This reveals the initiation altitude of those long delayed sprites and the effect of electric field dependence of the electron mobility.

  9. Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging.

    PubMed

    Chapman, Sandra B; Aslan, Sina; Spence, Jeffrey S; Defina, Laura F; Keebler, Molly W; Didehbani, Nyaz; Lu, Hanzhang

    2013-01-01

    Physical exercise, particularly aerobic exercise, is documented as providing a low cost regimen to counter well-documented cognitive declines including memory, executive function, visuospatial skills, and processing speed in normally aging adults. Prior aging studies focused largely on the effects of medium to long term (>6 months) exercise training; however, the shorter term effects have not been studied. In the present study, we examined changes in brain blood flow, cognition, and fitness in 37 cognitively healthy sedentary adults (57-75 years of age) who were randomized into physical training or a wait-list control group. The physical training group received supervised aerobic exercise for 3 sessions per week 1 h each for 12 weeks. Participants' cognitive, cardiovascular fitness and resting cerebral blood flow (CBF) were assessed at baseline (T1), mid (T2), and post-training (T3). We found higher resting CBF in the anterior cingulate region in the physical training group as compared to the control group from T1 to T3. Cognitive gains were manifested in the exercise group's improved immediate and delayed memory performance from T1 to T3 which also showed a significant positive association with increases in both left and right hippocampal CBF identified earlier in the time course at T2. Additionally, the two cardiovascular parameters, VO2 max and rating of perceived exertion (RPE) showed gains, compared to the control group. These data suggest that even shorter term aerobic exercise can facilitate neuroplasticity to reduce both the biological and cognitive consequences of aging to benefit brain health in sedentary adults.

  10. Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics

    PubMed Central

    Deutsch, Eric W.; Mendoza, Luis; Shteynberg, David; Slagel, Joseph; Sun, Zhi; Moritz, Robert L.

    2015-01-01

    Democratization of genomics technologies has enabled the rapid determination of genotypes. More recently the democratization of comprehensive proteomics technologies is enabling the determination of the cellular phenotype and the molecular events that define its dynamic state. Core proteomic technologies include mass spectrometry to define protein sequence, protein:protein interactions, and protein post-translational modifications. Key enabling technologies for proteomics are bioinformatic pipelines to identify, quantitate, and summarize these events. The Trans-Proteomics Pipeline (TPP) is a robust open-source standardized data processing pipeline for large-scale reproducible quantitative mass spectrometry proteomics. It supports all major operating systems and instrument vendors via open data formats. Here we provide a review of the overall proteomics workflow supported by the TPP, its major tools, and how it can be used in its various modes from desktop to cloud computing. We describe new features for the TPP, including data visualization functionality. We conclude by describing some common perils that affect the analysis of tandem mass spectrometry datasets, as well as some major upcoming features. PMID:25631240

  11. Post-project geomorphic assessment of a large process-based river restoration project

    USGS Publications Warehouse

    Erwin, Susannah O.; Schmidt, John C.; Allred, Tyler M.

    2016-01-01

    This study describes channel changes following completion of the Provo River Restoration Project (PRRP), the largest stream restoration project in Utah and one of the largest projects in the United States in which a gravel-bed river was fully reconstructed. We summarize project objectives and the design process, and we analyze monitoring data collected during the first 7 years after project completion. Post-project channel adjustment during the study period included two phases: (i) an initial phase of rapid, but small-scale, adjustment during the first years after stream flow was introduced to the newly constructed channel and (ii) a subsequent period of more gradual topographic adjustment and channel migration. Analysis of aerial imagery and ground-survey data demonstrate that the channel has been more dynamic in the downstream 4 km where a local source contributes a significant annual supply of bed material. Here, the channel migrates and exhibits channel adjustments that are more consistent with project objectives. The upstream 12 km of the PRRP are sediment starved, the channel has been laterally stable, and this condition may not be consistent with large-scale project objectives.

  12. Post-project geomorphic assessment of a large process-based river restoration project

    NASA Astrophysics Data System (ADS)

    Erwin, Susannah O.; Schmidt, John C.; Allred, Tyler M.

    2016-10-01

    This study describes channel changes following completion of the Provo River Restoration Project (PRRP), the largest stream restoration project in Utah and one of the largest projects in the United States in which a gravel-bed river was fully reconstructed. We summarize project objectives and the design process, and we analyze monitoring data collected during the first 7 years after project completion. Post-project channel adjustment during the study period included two phases: (i) an initial phase of rapid, but small-scale, adjustment during the first years after stream flow was introduced to the newly constructed channel and (ii) a subsequent period of more gradual topographic adjustment and channel migration. Analysis of aerial imagery and ground-survey data demonstrate that the channel has been more dynamic in the downstream 4 km where a local source contributes a significant annual supply of bed material. Here, the channel migrates and exhibits channel adjustments that are more consistent with project objectives. The upstream 12 km of the PRRP are sediment starved, the channel has been laterally stable, and this condition may not be consistent with large-scale project objectives.

  13. Groundwater in the Earth's critical zone: Relevance to large-scale patterns and processes

    NASA Astrophysics Data System (ADS)

    Fan, Ying

    2015-05-01

    Although we have an intuitive understanding of the behavior and functions of groundwater in the Earth's critical zone at the scales of a column (atmosphere-plant-soil-bedrock), along a toposequence (ridge to valley), and across a small catchment (up to third-order streams), this paper attempts to assess the relevance of groundwater to understanding large-scale patterns and processes such as represented in global climate and Earth system models. Through observation syntheses and conceptual models, evidence are presented that groundwater influence is globally prevalent, it forms an environmental gradient not fully captured by the climate, and it can profoundly shape critical zone evolution at continental to global scales. Four examples are used to illustrate these ideas: (1) groundwater as a water source for plants in rainless periods, (2) water table depth as a driver of plant rooting depth, (3) the accessibility of groundwater as an ecological niche separator, and (4) groundwater as the lower boundary of land drainage and a global driver of wetlands. The implications to understanding past and future global environmental change are briefly discussed, as well as critical discipline, scale, and data gaps that must be bridged in order for us to translate what we learn in the field at column, hillslope and catchment scales, to what we must predict at regional, continental, and global scales.

  14. Ultra-Smooth, Fully Solution-Processed Large-Area Transparent Conducting Electrodes for Organic Devices

    PubMed Central

    Jin, Won-Yong; Ginting, Riski Titian; Ko, Keum-Jin; Kang, Jae-Wook

    2016-01-01

    A novel approach for the fabrication of ultra-smooth and highly bendable substrates consisting of metal grid-conducting polymers that are fully embedded into transparent substrates (ME-TCEs) was successfully demonstrated. The fully printed ME-TCEs exhibited ultra-smooth surfaces (surface roughness ~1.0 nm), were highly transparent (~90% transmittance at a wavelength of 550 nm), highly conductive (sheet resistance ~4 Ω ◻−1), and relatively stable under ambient air (retaining ~96% initial resistance up to 30 days). The ME-TCE substrates were used to fabricate flexible organic solar cells and organic light-emitting diodes exhibiting devices efficiencies comparable to devices fabricated on ITO/glass substrates. Additionally, the flexibility of the organic devices did not degrade their performance even after being bent to a bending radius of ~1 mm. Our findings suggest that ME-TCEs are a promising alternative to indium tin oxide and show potential for application toward large-area optoelectronic devices via fully printing processes. PMID:27808221

  15. Ultra-Smooth, Fully Solution-Processed Large-Area Transparent Conducting Electrodes for Organic Devices

    NASA Astrophysics Data System (ADS)

    Jin, Won-Yong; Ginting, Riski Titian; Ko, Keum-Jin; Kang, Jae-Wook

    2016-11-01

    A novel approach for the fabrication of ultra-smooth and highly bendable substrates consisting of metal grid-conducting polymers that are fully embedded into transparent substrates (ME-TCEs) was successfully demonstrated. The fully printed ME-TCEs exhibited ultra-smooth surfaces (surface roughness ~1.0 nm), were highly transparent (~90% transmittance at a wavelength of 550 nm), highly conductive (sheet resistance ~4 Ω ◻‑1), and relatively stable under ambient air (retaining ~96% initial resistance up to 30 days). The ME-TCE substrates were used to fabricate flexible organic solar cells and organic light-emitting diodes exhibiting devices efficiencies comparable to devices fabricated on ITO/glass substrates. Additionally, the flexibility of the organic devices did not degrade their performance even after being bent to a bending radius of ~1 mm. Our findings suggest that ME-TCEs are a promising alternative to indium tin oxide and show potential for application toward large-area optoelectronic devices via fully printing processes.

  16. The Macro Model of the Inequality Process and the Surging Relative Frequency of Large Wage Incomes

    NASA Astrophysics Data System (ADS)

    Angle, John

    2008-03-01

    Particles are randomly paired in the Inequality Process (IP), a particle system scattering a positive quantity, wealth. Each particle has a parameter, φ, the fraction of wealth lost in a loss whose probability is 0.5. The stationary distribution of the wealth of particles with φψ is approximated by a γ pdf, the IP's macro model, with shape and scale parameters expressed in terms of φψ. The model's dynamics are driven by the product, φtμt, where φt is the harmonic mean of the φ's in the population at time t and μt, the population mean of wealth at time t. This γ pdf model fits the annual distribution of annual wage income in the U.S. 1961-2003. These data also confirm that the time-series of scalar statistics of wage income that labor economists think are produced by the U.S. distribution of wage income being ``hollowed out'' (bimodal), the increasing dispersion of wage income and the surging relative frequency of large wage incomes, are produced by the distribution being stretched over larger wage incomes, as implied by the IP's macro model when φtμt increases. The IP's macro model includes wage income distribution dynamics into statistical mechanics. To appear in The Econophysics of Markets and Business Networks.

  17. Feedbacks between Hydrological Processes in Tropical South America and Large-Scale Ocean-Atmospheric Phenomena.

    NASA Astrophysics Data System (ADS)

    Poveda, Germán; Mesa, Oscar J.

    1997-10-01

    The hydroclimatology of tropical South America is strongly coupled to low-frequency large-scale oceanicand atmospheric phenomena occurring over the Pacific and the Atlantic Oceans. In particular, El Niño-SouthernOscillation (ENSO) affects climatic and hydrologic conditions on timescales ranging from seasons to decades.With some regional differences in timing and amplitude, tropical South America exhibits negative rainfall andstreamflow anomalies in association with the low-warm phase of the Southern Oscillation (El Niño), and positiveanomalies with the high-cold phase. Such dependence is illustrated in the hydroclimatology of Colombia throughseveral empirical analyses: correlation, empirical orthogonal functions, principal component, and spectral analysis, and discussion of the major physical mechanisms. Observations show that ENSO's effect on river dischargesoccurs progressively later for rivers toward the east in Colombia and northern South America. Also, the impactsof La Niña are more pronounced than those of El Niño. Evidence is also presented to show that processes arisingfrom land-atmosphere interactions in tropical South America affect sea surface temperatures in the Caribbeanand the north tropical Atlantic. A hypothesis is formulated to explain these feedback mechanisms throughperturbations in precipitation, soil moisture, and evapotranspiration over the continent. To begin with, the occurrence of both phases of ENSO affects all those fields. The proposed mechanisms would constitute the `land-atmosphere' bridge connecting Pacific and Atlantic SST anomalies.

  18. Dust Processing Near Sites of High-Mass Star Formation in the Large Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Hony, Sacha; Madden, S.; Rubin, D.; Oey, M. S.; Galliano, F.; Whitney, B.; Meade, M.; Babler, B.; Indebetouw, R.; Hora, J.; Gordon, K.; Engelbracht, C.; For, B.; Block, M.; Misselt, K.; Meixner, M.; Vijh, U.; Leitherer, C.

    2006-12-01

    We present a study into the properties of the dust and complex molecules in and around selected Hii regions in the Large Magellanic Cloud. The analysis is based on the Spitzer program SAGE (Surveying the Agents of a Galaxy's Evolution). Because of the lower metallicity environment, dust shielding is reduced and the effects of the ultraviolet radiation carry further than in the Milky way. Because of this these Hii regions may well be better representatives of star forming regions in the more distant universe. We present the mid-IR spectral energy distributions (SEDs) as a function of radial distance to the center of the clusters: LHA 120-N4, N11, N63 and N105. These regions span a wide range in luminosities. The observed variations in SED are interpreted in terms of the varying incident radiation-field and changing abundances of polycyclic aromatic hydrocarbons (PAHs), transiently heated very small grains (VSG) to submicron-sized grains in thermal equilibrium, i.e. in terms of the varying grain-size distribution. This analysis allows us to quantify the dust destruction and/or processing-rate due to photoevaporation and the typical distance scale on which Hii regions impact their surroundings.

  19. Ultra-Smooth, Fully Solution-Processed Large-Area Transparent Conducting Electrodes for Organic Devices.

    PubMed

    Jin, Won-Yong; Ginting, Riski Titian; Ko, Keum-Jin; Kang, Jae-Wook

    2016-11-03

    A novel approach for the fabrication of ultra-smooth and highly bendable substrates consisting of metal grid-conducting polymers that are fully embedded into transparent substrates (ME-TCEs) was successfully demonstrated. The fully printed ME-TCEs exhibited ultra-smooth surfaces (surface roughness ~1.0 nm), were highly transparent (~90% transmittance at a wavelength of 550 nm), highly conductive (sheet resistance ~4 Ω ◻(-1)), and relatively stable under ambient air (retaining ~96% initial resistance up to 30 days). The ME-TCE substrates were used to fabricate flexible organic solar cells and organic light-emitting diodes exhibiting devices efficiencies comparable to devices fabricated on ITO/glass substrates. Additionally, the flexibility of the organic devices did not degrade their performance even after being bent to a bending radius of ~1 mm. Our findings suggest that ME-TCEs are a promising alternative to indium tin oxide and show potential for application toward large-area optoelectronic devices via fully printing processes.

  20. Active edge control in the precessions polishing process for manufacturing large mirror segments

    NASA Astrophysics Data System (ADS)

    Li, Hongyu; Zhang, Wei; Walker, David; Yu, Gouyo

    2014-09-01

    The segmentation of the primary mirror is the only promising solution for building the next generation of ground telescopes. However, manufacturing segmented mirrors presents its own challenges. The edge mis-figure impacts directly on the telescope's scientific output. The `Edge effect' significantly dominates the polishing precision. Therefore, the edge control is regarded as one of the most difficult technical issues in the segment production that needs to be addressed urgently. This paper reports an active edge control technique for the mirror segments fabrication using the Precession's polishing technique. The strategy in this technique requires that the large spot be selected on the bulk area for fast polishing, and the small spot is used for edge figuring. This can be performed by tool lift and optimizing the dell time to compensate for non-uniform material removal at the edge zone. This requires accurate and stable edge tool influence functions. To obtain the full tool influence function at the edge, we have demonstrated in previous work a novel hybrid-measurement method which uses both simultaneous phase interferometry and profilometry. In this paper, the edge effect under `Bonnet tool' polishing is investigated. The pressure distribution is analyzed by means of finite element analysis (FEA). According to the `Preston' equation, the shape of the edge tool influence functions is predicted. With this help, the multiple process parameters at the edge zone are optimized. This is demonstrated on a 200mm crosscorners hexagonal part with a result of PV less than 200nm for entire surface.

  1. Electrical and optical characterization of an atmospheric pressure, uniform, large-area processing, dielectric barrier discharge

    NASA Astrophysics Data System (ADS)

    Zeniou, A.; Puač, N.; Škoro, N.; Selaković, N.; Dimitrakellis, P.; Gogolides, E.; Petrović, Z. Lj

    2017-04-01

    A printed-circuit-board (PCB) based atmospheric pressure dielectric barrier discharge (DBD) capable of uniform processing over a large area was constructed consisting of two parallel plates. The first perforated plate is comprised of four layers: a RF powered metal layer, a polymeric dielectric layer, a floating metal grid and another dielectric layer. The second, grounded, plate was fluorine doped tin oxide (FTO) glass plate with surface of 100  ×  100 mm2 and thickness of 2 mm. The PCB based atmospheric pressure DBD was characterized by (a) measuring electrical characteristics of the device using derivative I–V probes, (b) ICCD imaging and (c) optical emission spectroscopy (OES). Optical and electrical characteristics, as well as plasma uniformity were measured by changing He flow rate and input power, while keeping the gap between the PCB and the FTO glass plate ground electrode constant at 2 mm. The plasma uniformity strongly depends on the applied power and on the flow rate of the buffer gas. When increasing the flow rate, the intensity of the nitrogen-dominated emission drops, while emission of helium and oxygen lines increases. The source allows low temperature, uniform plasma operation over a wide area of 100  ×  100 mm2, which could be essential for numerous applications. Examples of etching rate and hydrophilization are demonstrated.

  2. Control considerations for high frequency, resonant, power processing equipment used in large systems

    NASA Technical Reports Server (NTRS)

    Mildice, J. W.; Schreiner, K. E.; Wolff, F.

    1987-01-01

    Addressed is a class of resonant power processing equipment designed to be used in an integrated high frequency (20 KHz domain), utility power system for large, multi-user spacecraft and other aerospace vehicles. It describes a hardware approach, which has been the basis for parametric and physical data used to justify the selection of high frequency ac as the PMAD baseline for the space station. This paper is part of a larger effort undertaken by NASA and General Dynamics to be sure that all potential space station contractors and other aerospace power system designers understand and can comfortably use this technology, which is now widely used in the commercial sector. In this paper, we will examine control requirements, stability, and operational modes; and their hardware impacts from an integrated system point of view. The current space station PMAD system will provide the overall requirements model to develop an understanding of the performance of this type of system with regard to: (1) regulation; (2) power bus stability and voltage control; (3) source impedance; (4) transient response; (5) power factor effects; and (6) limits and overloads.

  3. Control considerations for high frequency, resonant, power processing equipment used in large systems

    NASA Technical Reports Server (NTRS)

    Mildice, J. W.; Schreiner, K. E.; Wolff, F.

    1987-01-01

    Addressed is a class of resonant power processing equipment designed to be used in an integrated high frequency (20 KHz domain), utility power system for large, multi-user spacecraft and other aerospace vehicles. It describes a hardware approach, which has been the basis for parametric and physical data used to justify the selection of high frequency ac as the PMAD baseline for the space station. This paper is part of a larger effort undertaken by NASA and General Dynamics to be sure that all potential space station contractors and other aerospace power system designers understand and can comfortably use this technology, which is now widely used in the commercial sector. In this paper, we will examine control requirements, stability, and operational modes; and their hardware impacts from an integrated system point of view. The current space station PMAD system will provide the overall requirements model to develop an understanding of the performance of this type of system with regard to: (1) regulation; (2) power bus stability and voltage control; (3) source impedance; (4) transient response; (5) power factor effects, and (6) limits and overloads.

  4. Replicating Scour Processes around Large Wood in a Simplified Flume Study

    NASA Astrophysics Data System (ADS)

    Russell, K.; Svoboda, C.; Gordon, E.

    2011-12-01

    surfaces and GPS surveys for underwater surfaces. These data were combined to develop continuous surfaces. The work presented includes a comparison of the flume and field topographic and habitat data. Comparisons were made between spatial variability and volumetric changes near the structure. The habitat around the field structure (based on a biological assessment) and habitat created in the laboratory experiment were also compared. There were scaling and practical limitations that prevent exact replication of the field conditions. Although the 2-year discharge in the field corresponds to an out of bank flow in the flume the 90% bankfull discharge provides a close approximation. In addition, the flume experiments were conducted under a clear water condition (no upstream sediment feed), which provides a more conservative estimate of scour than if sediment were being supplied. Finally, replicating the combined hydrologic and sediment transport processes in the flume was complicated because scour pools developed in the field likely had some filling during the falling limb of the hydrograph. Despite the challenges associated with the flume modeling, the results indicate that the laboratory experiments can provide useful information for future installations of large wood.

  5. Anamet anaerobic-aerobic treatment of concentrated wastewaters

    SciTech Connect

    Frostell, B.

    1982-01-01

    The process, consisting of a closed anaerobic tank reactor with side mounted agitator and electric heaters to control temperature at 35-37 degrees, an external solids separator for recycle of anaerobic sludge, an open aerobic tank reactor with an air sparger at the bottom, and a conical settling clarifier to separate and recycle aerobic sludge, decreased the COD from 3-89 to 0.10-18 and the BOD5 from 1.4-26 to 0.03-0.30 g O2/L in dairy, vegetable cannery, beet sugar, wheat starch, mixed pulp and paper, citric acid, and rum distillery wastewater. Recoveries of CH4-containing gas produced by the process were 69-107% of theory. Total excess sludge production was only 0.05 kg/kg COD added or 0.06 kg/kg COD removed.

  6. Performance of sequential anaerobic/aerobic digestion applied to municipal sewage sludge.

    PubMed

    Tomei, M Concetta; Rita, Sara; Mininni, Giuseppe

    2011-07-01

    A promising alternative to conventional single phase processing, the use of sequential anaerobic-aerobic digestion, was extensively investigated on municipal sewage sludge from a full scale wastewater treatment plant. The objective of the work was to evaluate sequential digestion performance by testing the characteristics of the digested sludge in terms of volatile solids (VS), Chemical Oxygen Demand (COD) and nitrogen reduction, biogas production, dewaterability and the content of proteins and polysaccharides. VS removal efficiencies of 32% in the anaerobic phase and 17% in the aerobic one were obtained, and similar COD removal efficiencies (29% anaerobic and 21% aerobic) were also observed. The aerobic stage was also efficient in nitrogen removal providing a decrease of the nitrogen content in the supernatant attributable to nitrification and simultaneous denitrification. Moreover, in the aerobic phase an additional marked removal of proteins and polysaccharides produced in the anaerobic phase was achieved. The sludge dewaterability was evaluated by determining the Optimal Polymer Dose (OPD) and the Capillary Suction Time (CST) and a significant positive effect due to the aerobic stage was observed. Biogas production was close to the upper limit of the range of values reported in the literature in spite of the low anaerobic sludge retention time of 15 days. From a preliminary analysis it was found that the energy demand of the aerobic phase was significantly lower than the recovered energy in the anaerobic phase and the associated additional cost was negligible in comparison to the saving derived from the reduced amount of sludge to be disposed.

  7. Environmental control on aerobic methane oxidation in coastal waters

    NASA Astrophysics Data System (ADS)

    Steinle, Lea; Maltby, Johanna; Engbersen, Nadine; Zopfi, Jakob; Bange, Hermann; Elvert, Marcus; Hinrichs, Kai-Uwe; Kock, Annette; Lehmann, Moritz; Treude, Tina; Niemann, Helge

    2016-04-01

    Large quantities of methane are produced in anoxic sediments of continental margins and may be liberated to the overlying water column, where some of it is consumed by aerobic methane oxidizing bacteria (MOB). Aerobic methane oxidation (MOx) in the water column is consequently the final sink for methane before its release to the atmosphere, where it acts as a potent greenhouse gas. In the context of the ocean's contribution to atmospheric methane, coastal seas are particularly important accounting >75% of global methane emission from marine systems. Coastal oceans are highly dynamic, in particular with regard to the variability of methane and oxygen concentrations as well as temperature and salinity, all of which are potential key environmental factors controlling MOx. To determine important environmental controls on the activity of MOBs in coastal seas, we conducted a two-year time-series study with measurements of physicochemical water column parameters, MOx activity and the composition of the MOB community in a coastal inlet in the Baltic Sea (Boknis Eck Time Series Station, Eckernförde Bay - E-Bay). In addition, we investigated the influence of temperature and oxygen on MOx during controlled laboratory experiments. In E-Bay, hypoxia developed in bottom waters towards the end of the stratification period. Constant methane liberation from sediments resulted in bottom water methane accumulations and supersaturation (with respect to the atmospheric equilibrium) in surface waters. Here, we will discuss the factors impacting MOx the most, which were (i) perturbations of the water column (ii) temperature and (iii) oxygen concentration. (i) Perturbations of the water column caused by storm events or seasonal mixing led to a decrease in MOx, probably caused by replacement of stagnant water with a high standing stock of MOB by 'new' waters with a lower abundance of methanotrophs. b) An increase in temperature generally led to higher MOx rates. c) Even though methane was

  8. TOPICAL REVIEW: Large REBCO single crystals: growth processes and superconducting properties

    NASA Astrophysics Data System (ADS)

    Yao, X.; Shiohara, Y.

    1997-05-01

    A low solubility of yttrium in the Ba - Cu - O melt and a steep liquidus slope near the peritectic temperature 0953-2048/10/5/001/img1 lead to a very slow growth rate of 0953-2048/10/5/001/img2 (YBCO or Y123) single crystals and this creates a problem in growth of large single crystals. To solve this problem, increasing the growth rate and extending the growth time are significant. Using the crystal pulling method, we have developed several processes and succeeded in growing large Y123 and 0953-2048/10/5/001/img3 (NdBCO) single crystals with an edge size over 25 mm in the a - b plane and up to 20 mm in the c-axis direction. In this article, three methods of increasing growth rate are reviewed. They are (i) employing high oxygen partial pressure, (ii) choosing RE (rare earth) elements with higher solubilities in the Ba - Cu - O solution, and (iii) growing REBCO crystals including several RE elements. Using these methods the growth rate was effectively enhanced from two to five times that of Y123. The critical temperature 0953-2048/10/5/001/img4 of 92.7 K was achieved from a Y123 single crystal grown under 1 atm oxygen partial pressure, indicating that 0953-2048/10/5/001/img4 is insensitive to the oxygen pressure of the growth atmosphere in the YBCO system. A high 0953-2048/10/5/001/img4 of about 95 K for NdBCO superconductors with a sharp transition was obtained by controlling the ratio of Ba to Cu (Ba/Cu) in the liquid, suggesting that the Ba/Cu ratio in the liquid composition has a significant importance in controlling 0953-2048/10/5/001/img4. By partial substitution of Sm at the Y sites up to 30%, 0953-2048/10/5/001/img8 (Y(Sm)BCO) crystals show a 0953-2048/10/5/001/img4 of 0953-2048/10/5/001/img10 and do not display 0953-2048/10/5/001/img4 depression.

  9. Successful treatment of high azo dye concentration wastewater using combined anaerobic/aerobic granular activated carbon-sequencing batch biofilm reactor (GAC-SBBR): simultaneous adsorption and biodegradation processes.

    PubMed

    Hosseini Koupaie, E; Alavi Moghaddam, M R; Hashemi, S H

    2013-01-01

    The application of a granular activated carbon-sequencing batch biofilm reactor (GAC-SBBR) for treatment of wastewater containing 1,000 mg/L Acid Red 18 (AR18) was investigated in this research. The treatment system consisted of a sequencing batch reactor equipped with moving GAC as biofilm support. Each treatment cycle consisted of two successive anaerobic (14 h) and aerobic (8 h) reaction phases. Removal of more than 91% chemical oxygen demand (COD) and 97% AR18 was achieved in this study. Investigation of dye decolorization kinetics showed that the dye removal was stimulated by the adsorption capacity of the GAC at the beginning of the anaerobic phase and then progressed following a first-order reaction. Based on COD analysis results, at least 77.8% of the dye total metabolites were mineralized during the applied treatment system. High-performance liquid chromatography analysis revealed that more than 97% of 1-naphthyalamine-4-sulfonate as one of the main sulfonated aromatic constituents of AR18 was removed during the aerobic reaction phase. According to the scanning electron microscopic analysis, the microbial biofilms grew in most cavities and pores of the GAC, but not on the external surfaces of the GAC.

  10. Aerobic fitness ecological validity in elite soccer players: a metabolic power approach.

    PubMed

    Manzi, Vincenzo; Impellizzeri, Franco; Castagna, Carlo

    2014-04-01

    The aim of this study was to examine the association between match metabolic power (MP) categories and aerobic fitness in elite-level male soccer players. Seventeen male professional soccer players were tested for VO2max, maximal aerobic speed (MAS), VO2 at ventilatory threshold (VO2VT and %VO2VT), and speed at a selected blood lactate concentration (4 mmol·L(-1), V(L4)). Aerobic fitness tests were performed at the end of preseason and after 12 and 24 weeks during the championship. Aerobic fitness and MP variables were considered as mean of all seasonal testing and of 16 Championship home matches for all the calculations, respectively. Results showed that VO2max (from 0.55 to 0.68), MAS (from 0.52 to 0.72), VO2VT (from 0.72 to 0.83), %VO2maxVT (from 0.62 to 0.65), and V(L4) (from 0.56 to 0.73) were significantly (p < 0.05 to 0.001) large to very large associated with MP variables. These results provide evidence to the ecological validity of aerobic fitness in male professional soccer. Strength and conditioning professionals should consider aerobic fitness in their training program when dealing with professional male soccer players. The MP method resulted an interesting approach for tracking external load in male professional soccer players.

  11. A Largely Unsatisfied Need: Continuing Professional Development for Process and Process Plant Industries. A Summary. FEU/PICKUP Project Report.

    ERIC Educational Resources Information Center

    Geldhart, D.; Brown, A. S.

    This summary report outlines the aims of a project that focused on provision of short courses for technical professionals in the chemical and allied process industry and the process plant industry. Continuing education needs of both companies and individuals, as well as corporate policies and attitudes toward continuing education and constraints…

  12. Large eddy simulations of turbulent flows on graphics processing units: Application to film-cooling flows

    NASA Astrophysics Data System (ADS)

    Shinn, Aaron F.

    Computational Fluid Dynamics (CFD) simulations can be very computationally expensive, especially for Large Eddy Simulations (LES) and Direct Numerical Simulations (DNS) of turbulent ows. In LES the large, energy containing eddies are resolved by the computational mesh, but the smaller (sub-grid) scales are modeled. In DNS, all scales of turbulence are resolved, including the smallest dissipative (Kolmogorov) scales. Clusters of CPUs have been the standard approach for such simulations, but an emerging approach is the use of Graphics Processing Units (GPUs), which deliver impressive computing performance compared to CPUs. Recently there has been great interest in the scientific computing community to use GPUs for general-purpose computation (such as the numerical solution of PDEs) rather than graphics rendering. To explore the use of GPUs for CFD simulations, an incompressible Navier-Stokes solver was developed for a GPU. This solver is capable of simulating unsteady laminar flows or performing a LES or DNS of turbulent ows. The Navier-Stokes equations are solved via a fractional-step method and are spatially discretized using the finite volume method on a Cartesian mesh. An immersed boundary method based on a ghost cell treatment was developed to handle flow past complex geometries. The implementation of these numerical methods had to suit the architecture of the GPU, which is designed for massive multithreading. The details of this implementation will be described, along with strategies for performance optimization. Validation of the GPU-based solver was performed for fundamental bench-mark problems, and a performance assessment indicated that the solver was over an order-of-magnitude faster compared to a CPU. The GPU-based Navier-Stokes solver was used to study film-cooling flows via Large Eddy Simulation. In modern gas turbine engines, the film-cooling method is used to protect turbine blades from hot combustion gases. Therefore, understanding the physics of

  13. Graphics Processing Unit Acceleration and Parallelization of GENESIS for Large-Scale Molecular Dynamics Simulations.

    PubMed

    Jung, Jaewoon; Naurse, Akira; Kobayashi, Chigusa; Sugita, Yuji

    2016-10-11

    The graphics processing unit (GPU) has become a popular computational platform for molecular dynamics (MD) simulations of biomolecules. A significant speedup in the simulations of small- or medium-size systems using only a few computer nodes with a single or multiple GPUs has been reported. Because of GPU memory limitation and slow communication between GPUs on different computer nodes, it is not straightforward to accelerate MD simulations of large biological systems that contain a few million or more atoms on massively parallel supercomputers with GPUs. In this study, we develop a new scheme in our MD software, GENESIS, to reduce the total computational time on such computers. Computationally intensive real-space nonbonded interactions are computed mainly on GPUs in the scheme, while less intensive bonded interactions and communication-intensive reciprocal-space interactions are performed on CPUs. On the basis of the midpoint cell method as a domain decomposition scheme, we invent the single particle interaction list for reducing the GPU memory usage. Since total computational time is limited by the reciprocal-space computation, we utilize the RESPA multiple time-step integration and reduce the CPU resting time by assigning a subset of nonbonded interactions on CPUs as well as on GPUs when the reciprocal-space computation is skipped. We validated our GPU implementations in GENESIS on BPTI and a membrane protein, porin, by MD simulations and an alanine-tripeptide by REMD simulations. Benchmark calculations on TSUBAME supercomputer showed that an MD simulation of a million atoms system was scalable up to 256 computer nodes with GPUs.

  14. Complex Nucleation Process of Large North Chile Earthquakes, Implications for Early Warning Systems

    NASA Astrophysics Data System (ADS)

    Ruiz, S.; Meneses, G.; Sobiesiak, M.; Madariaga, R. I.

    2014-12-01

    We studied the nucleation process of Northern Chile events that included the large earthquakes of Tocopilla 2007 Mw 7.8 and Iquique 2014 Mw 8.1, as well as the background seismicity recorded from 2011 to 2013 by the ILN temporary network and the IPOC and CSN permanent networks. We built our catalogue of 393 events starting from the CSN catalogue, which has a completeness of magnitude Mw > 3.0 in Northern Chile. We re-located and computed moment magnitude for each event. We also computed Early Warning (EW) parameters - Pd, Pv, τc and IV2 - for each event including 13 earthquakes of Mw>6.0 that occurred between 2007-2012. We also included part of the seismicity from March-April 2014 period. We find that Pd, Pv and IV2 are good estimators of magnitude for interplate thrust and intraplate intermediate depth events with Mw between 4.0 and 6.0. However, the larger magnitude events show a saturation of the EW parameters. The Tocopilla 2007 and Iquique 2014 earthquake sequences were studied in detail. Almost all events with Mw>6.0 present precursory signals so that the largest amplitudes occur several seconds after the first P wave arrival. The recent Mw 8.1 Iquique 2014 earthquake was preceded by low amplitude P waves for 20 s before the main asperity was broken. The magnitude estimation can improve if we consider longer P wave windows in the estimation of EW parameters. There was, however, a practical limit during the Iquique earthquake because the first S waves arrived before the arrival of the P waves from the main rupture. The 4 s P-wave Pd parameter estimated Mw 7.1 for the Mw 8.1 Iquique 2014 earthquake and Mw 7.5 for the Mw 7.8 Tocopilla 2007 earthquake.

  15. Developing Software Requirements for a Knowledge Management System That Coordinates Training Programs with Business Processes and Policies in Large Organizations

    ERIC Educational Resources Information Center

    Kiper, J. Richard

    2013-01-01

    For large organizations, updating instructional programs presents a challenge to keep abreast of constantly changing business processes and policies. Each time a process or policy changes, significant resources are required to locate and modify the training materials that convey the new content. Moreover, without the ability to track learning…

  16. Reducing Plug and Process Loads for a Large Scale, Low Energy Office Building: NREL's Research Support Facility; Preprint

    SciTech Connect

    Lobato, C.; Pless, S.; Sheppy, M.; Torcellini, P.

    2011-02-01

    This paper documents the design and operational plug and process load energy efficiency measures needed to allow a large scale office building to reach ultra high efficiency building goals. The appendices of this document contain a wealth of documentation pertaining to plug and process load design in the RSF, including a list of equipment was selected for use.

  17. Fit women are not able to use the whole aerobic capacity during aerobic dance.

    PubMed

    Edvardsen, Elisabeth; Ingjer, Frank; Bø, Kari

    2011-12-01

    Edvardsen, E, Ingjer, F, and Bø, K. Fit women are not able to use the whole aerobic capacity during aerobic dance. J Strength Cond Res 25(12): 3479-3485, 2011-This study compared the aerobic capacity during maximal aerobic dance and treadmill running in fit women. Thirteen well-trained female aerobic dance instructors aged 30 ± 8.17 years (mean ± SD) exercised to exhaustion by running on a treadmill for measurement of maximal oxygen uptake (VO(2)max) and peak heart rate (HRpeak). Additionally, all subjects performed aerobic dancing until exhaustion after a choreographed videotaped routine trying to reach the same HRpeak as during maximal running. The p value for statistical significance between running and aerobic dance was set to ≤0.05. The results (mean ± SD) showed a lower VO(2)max in aerobic dance (52.2 ± 4.02 ml·kg·min) compared with treadmill running (55.9 ± 5.03 ml·kg·min) (p = 0.0003). Further, the mean ± SD HRpeak was 182 ± 9.15 b·min in aerobic dance and 192 ± 9.62 b·min in treadmill running, giving no difference in oxygen pulse between the 2 exercise forms (p = 0.32). There was no difference in peak ventilation (aerobic dance: 108 ± 10.81 L·min vs. running: 113 ± 11.49 L·min). In conclusion, aerobic dance does not seem to be able to use the whole aerobic capacity as in running. For well endurance-trained women, this may result in a lower total workload at maximal intensities. Aerobic dance may therefore not be as suitable as running during maximal intensities in well-trained females.

  18. Performances and microbial features of an aerobic packed-bed biofilm reactor developed to post-treat an olive mill effluent from an anaerobic GAC reactor

    PubMed Central

    Bertin, Lorenzo; Colao, Maria Chiara; Ruzzi, Maurizio; Marchetti, Leonardo; Fava, Fabio

    2006-01-01

    Background Olive mill wastewater (OMW) is the aqueous effluent of olive oil producing processes. Given its high COD and content of phenols, it has to be decontaminated before being discharged. Anaerobic digestion is one of the most promising treatment process for such an effluent, as it combines high decontamination efficiency with methane production. The large scale anaerobic digestion of OMWs is normally conducted in dispersed-growth reactors, where however are generally achieved unsatisfactory COD removal and methane production yields. The possibility of intensifying the performance of the process using a packed bed biofilm reactor, as anaerobic treatment alternative, was demonstrated. Even in this case, however, a post-treatment step is required to further reduce the COD. In this work, a biological post-treatment, consisting of an aerobic biological "Manville" silica bead-packed bed aerobic reactor, was developed, tested for its ability to complete COD removal from the anaerobic digestion effluents, and characterized biologically through molecular tools. Results The aerobic post-treatment was assessed through a 2 month-continuous feeding with the digested effluent at 50.42 and 2.04 gl-1day-1 of COD and phenol loading rates, respectively. It was found to be a stable process, able to remove 24 and 39% of such organic loads, respectively, and to account for 1/4 of the overall decontamination efficiency displayed by the anaerobic-aerobic integrated system when fed with an amended OMW at 31.74 and 1.70 gl-1day-1 of COD and phenol loading rates, respectively. Analysis of 16S rRNA gene sequences of biomass samples from the aerobic reactor biofilm revealed that it was colonized by Rhodobacterales, Bacteroidales, Pseudomonadales, Enterobacteriales, Rhodocyclales and genera incertae sedis TM7. Some taxons occurring in the influent were not detected in the biofilm, whereas others, such as Paracoccus, Pseudomonas, Acinetobacter and Enterobacter, enriched significantly in

  19. Characterization, Modeling and Application of Aerobic Granular Sludge for Wastewater Treatment

    NASA Astrophysics Data System (ADS)

    Liu, Xian-Wei; Yu, Han-Qing; Ni, Bing-Jie; Sheng, Guo-Ping

    Recently extensive studies have been carried out to cultivate aerobic granular sludge worldwide, including in China. Aerobic granules, compared with conventional activated sludge flocs, are well known for their regular, dense, and strong microbial structure, good settling ability, high biomass retention, and great ability to withstand shock loadings. Studies have shown that the aerobic granules could be applied for the treatment of low- or high-strength wastewaters, simultaneous removal of organic carbon, nitrogen and phosphorus, and decomposition of toxic wastewaters. Thus, this new form of activate sludge, like anaerobic granular sludge, could be employed for the treatment of municipal and industrial wastewaters in near future. This chapter attempts to provide an up-to-date review on the definition, cultivation, characterization, modeling and application of aerobic granular sludge for biological wastewater treatment. This review outlines some important discoveries with regard to the factors affecting the formation of aerobic granular sludge, their physicochemical characteristics, as well as their microbial structure and diversity. It also summarizes the modeling of aerobic granule formation. Finally, this chapter highlights the applications of aerobic granulation technology in the biological wastewater treatment. It is concluded that the knowledge regarding aerobic granular sludge is far from complete. Although previous studies in this field have undoubtedly improved our understanding on aerobic granular sludge, it is clear that much remains to be learned about the process and that many unanswered questions still remain. One of the challenges appears to be the integration of the existing and growing scientific knowledge base with the observations and applications in practice, which this paper hopes to partially achieve.

  20. The impact of nanoparticles on aerobic degradation of municipal solid waste.

    PubMed

    Yazici Guvenc, Senem; Alan, Burcu; Adar, Elanur; Bilgili, Mehmet Sinan

    2017-04-01

    The amount of nanoparticles released from industrial and consumer products has increased rapidly in the last decade. These products may enter landfills directly or indirectly after the end of their useful life. In order to determine the impact of TiO2 and Ag nanoparticles on aerobic landfilling processes, municipal solid waste was loaded to three pilot-scale aerobic landfill bioreactors (80 cm diameter and 350 cm height) and exposed to TiO2 (AT) and Ag (AA) nanoparticles at total concentrations of 100 mg kg(-1) of solid waste. Aerobic landfill bioreactors were operated under the conditions about 0.03 L min(-1) kg(-1) aeration rate for 250 days, during which the leachate, solid waste, and gas characteristics were measured. The results indicate that there was no significant difference in the leachate characteristics, gas constituents, solid quality parameters, and temperature variations, which are the most important indicators of landfill operations, and overall aerobic degradation performance between the reactors containing TiO2 and Ag nanoparticles, and control (AC) reactor. The data also indicate that the pH levels, ionic strength, and the complex formation capacity of nanoparticles with Cl(-) ions can reduce the toxicity effects of nanoparticles on aerobic degradation processes. The results suggest that TiO2 and Ag nanoparticles at concentrations of 100 mg kg(-1) of solid waste do not have significant impacts on aerobic biological processes and waste management systems.

  1. COPASutils: an R package for reading, processing, and visualizing data from COPAS large-particle flow cytometers.

    PubMed

    Shimko, Tyler C; Andersen, Erik C

    2014-01-01

    The R package COPASutils provides a logical workflow for the reading, processing, and visualization of data obtained from the Union Biometrica Complex Object Parametric Analyzer and Sorter (COPAS) or the BioSorter large-particle flow cytometers. Data obtained from these powerful experimental platforms can be unwieldy, leading to difficulties in the ability to process and visualize the data using existing tools. Researchers studying small organisms, such as Caenorhabditis elegans, Anopheles gambiae, and Danio rerio, and using these devices will benefit from this streamlined and extensible R package. COPASutils offers a powerful suite of functions for the rapid processing and analysis of large high-throughput screening data sets.

  2. Quantification of aerobic biodegradation and volatilization rates of gasoline hydrocarbons near the water table under natural attenuation conditions

    USGS Publications Warehouse

    Lahvis, M.A.; Baehr, A.L.; Baker, R.J.

    1999-01-01

    Aerobic biodegradation and volatilization near the water table constitute a coupled pathway that contributes significantly to the natural attenuation of hydrocarbons at gasoline spill sites. Rates of hydrocarbon biodegradation and volatilization were quantified by analyzing vapor transport in the unsaturated zone at a gasoline spill site in Beaufort, South Carolina. Aerobic biodegradation rates decreased with distance above the water table, ranging from 0.20 to 1.5g m-3 d-1 for toluene, from 0.24 to 0.38 g m-3 d-1 for xylene, from 0.09 to 0.24 g m-3 d-1 for cyclohexene, from 0.05 to 0.22 g m-3 d-1 for ethylbenzene, and from 0.02 to 0.08 g m-3 d-1 for benzene. Rates were highest in the capillary zone, where 68% of the total hydrocarbon mass that volatilized from the water table was estimated to have been biodegraded. Hydrocarbons were nearly completely degraded within 1 m above the water table. This large loss underscores the importance of aerobic biodegradation in limiting the transport of hydrocarbon vapors in the unsaturated zone and implies that vapor-plume migration to basements and other points of contact may only be significant if a source of free product is present. Furthermore, because transport of the hydrocarbon in the unsaturated zone can be limited relative to that of oxygen and carbon dioxide, soil, gas surveys conducted at hydrocarbon-spill sites would benefit by the inclusion of oxygen- and carbon-dioxide-gas concentration measurements. Aerobic degradation kinetics in the unsaturated zone were approximately first-order. First-order rate constants near the water table were highest for cyctohexene (0.21-0.65 d-1) and nearly equivalent for ethylbenzene (0.11-20.31 d-1), xylenes (0.10-0.31 d-1), toluene (0.09-0.30 d-1), and benzene (0.07,0.31 d-1). Hydrocarbon mass loss rates at the water table resulting from the coupled aerobic biodegradation and volatilization process were determined by extrapolating gas transport rates through the capillary zone. Mass

  3. Small and Large Number Processing in Infants and Toddlers with Williams Syndrome

    ERIC Educational Resources Information Center

    Van Herwegen, Jo; Ansari, Daniel; Xu, Fei; Karmiloff-Smith, Annette

    2008-01-01

    Previous studies have suggested that typically developing 6-month-old infants are able to discriminate between small and large numerosities. However, discrimination between small numerosities in young infants is only possible when variables continuous with number (e.g. area or circumference) are confounded. In contrast, large number discrimination…

  4. Fine-Scale Relief in the Amazon Drives Large Scale Ecohydrological Processes

    NASA Astrophysics Data System (ADS)

    Nobre, A. D.; Cuartas, A.; Hodnett, M.; Saleska, S. R.

    2014-12-01

    Access to soil water by roots is a key ecophysiological factor for plant productivity in natural systems. Periodically during dry seasons or critically during episodic climate droughts, shortage of water supply can reduce or severely impair plant life. At the other extreme persistent soil waterlogging will limit root respiration and restrict local establishment to adapted species, usually leading to stunted and less productive communities. Soil-water availability is therefore a very important climate variable controlling plant physiology and ecosystem dynamics. Terra-firme, the non-seasonally floodable terrain that covers 82% of the landscape in Amazonia,[1] supports the most massive part of the rainforest ecosystem. The availability of soil water data for terra-firme is scant and very coarse. This lack of data has hampered observational and modeling studies aiming to develop a large-scale integrative ecohydrological picture of Amazonia and its vulnerability to climate change. We have mapped the Amazon basin with a new terrain model developed in our group (HAND, Height Above the Nearest drainage[2]), delineating soil water environments using topographical data from the SRTM digital elevation model (250 m horizontal interpolated resolution). The preliminary results show that more than 50% of Terra-firme has the water table very close to the surface (up to 2 m deep), while the remainder of the upland landscape has variable degree of dependence on non-saturated soil (vadose layer). The mapping also shows extremely heterogeneous patterns of fine-scale relief across the basin, which implies complex ecohydrological regional forcing on the forest physiology. Ecoclimate studies should therefore take into account fine-scale relief and its implications for soil-water availability to plant processes. [1] Melack, J. M., & Hess, L. L. (2011). Remote sensing of the distribution and extent of wetlands in the Amazon basin. In W. J. Junk & M. Piedade (Eds.), Amazonian floodplain

  5. Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis.

    PubMed

    Tao, Tao; Chen, Ming; Jiang, Ranran; Guan, Han; Huang, Yeqing; Su, Huan; Hu, Qiang; Han, Xu; Xiao, Jun

    2017-03-01

    Recent studies suggest that several types of tumors preferentially metabolize glucose through aerobic glycolysis, a phenomenon known as the Warburg effect. However, it remains largely unexplored whether metabolic reprogramming is involved in prostate cancer (PCa) progression. In this study, we found that histone methyltransferase enhancer of zeste homolog 2 (EZH2) dysregulated in PCa development regulated cellular growth and aerobic glycolysis through miR-181b/hexokinase 2 (HK2) axis. Aberrant expression profiles of coding RNA and microRNA were examined by two large, independent clinical prostate cancer data sets. The results indicated that EZH2 expression was elevated followed by PCa development. A set of glycometabolism-related genes were positively correlated with EZH2 expression such as HK2.The depletion of EZH2 in cell experiments inhibited PCa cell growth and aerobic glycolysis accompanying the up-regulation of miR-181b. Western blot and luciferase reporter assays showed that miR-181b inversely modulated HK2 by directly targeting the binding site within 3'-untranslated regions. Moreover, decreased miR-181b expression largely abrogated the effect of sh-EZH2 on HK2 expression and HK2-induced glucose metabolism process. Immunohistochemistry (IHC) and in situ hybridisation (ISH) analysis further revealed a significant correlation in EZH2, miR-181b and HK2 expression in nude mouse tumor xenograft. Taken together, these findings provide the first evidence that EZH2/miR-181b/HK2 pathway plays a positive role in PCa development. Targeting this aberrantly activated pathway may provide a new therapeutic strategy against PCa.

  6. Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis

    PubMed Central

    Tao, Tao; Chen, Ming; Jiang, Ranran; Guan, Han; Huang, Yeqing; Su, Huan; Hu, Qiang; Han, Xu; Xiao, Jun

    2017-01-01

    Recent studies suggest that several types of tumors preferentially metabolize glucose through aerobic glycolysis, a phenomenon known as the Warburg effect. However, it remains largely unexplored whether metabolic reprogramming is involved in prostate cancer (PCa) progression. In this study, we found that histone methyltransferase enhancer of zeste homolog 2 (EZH2) dysregulated in PCa development regulated cellular growth and aerobic glycolysis through miR-181b/hexokinase 2 (HK2) axis. Aberrant expression profiles of coding RNA and microRNA were examined by two large, independent clinical prostate cancer data sets. The results indicated that EZH2 expression was elevated followed by PCa development. A set of glycometabolism-related genes were positively correlated with EZH2 expression such as HK2. The depletion of EZH2 in cell experiments inhibited PCa cell growth and aerobic glycolysis accompanying the upregulation of miR-181b. Western blot and luciferase reporter assays showed that miR-181b inversely modulated HK2 by directly targeting the binding site within 3′-untranslated regions. Moreover, decreased miR-181b expression largely abrogated the effect of sh-EZH2 on HK2 expression and HK2-induced glucose metabolism process. Immunohistochemistry (IHC) and in situ hybridisation (ISH) analysis further revealed a significant correlation in EZH2, miR-181b and HK2 expression in nude mouse tumor xenograft. Taken together, these findings provide the first evidence that EZH2/miR-181b/HK2 pathway plays a positive role in PCa development. Targeting this aberrantly activated pathway may provide a new therapeutic strategy against PCa. PMID:28184935

  7. The effects of aerobic training on children's creativity, self-perception, and aerobic power.

    PubMed

    Herman-Tofler, L R; Tuckman, B W

    1998-10-01

    The article examines whether participation in an aerobic exercise program (AE), as compared with a traditional physical education class (PE), significantly increased children's perceived athletic competence, physical appearance, social acceptance, behavioral conduct, and global self-worth; increased their figural creativity; and improved aerobic power as measured by an 800-meter run around a track. Further research on the effects of different types of AE is discussed, as well as the need for aerobic conditioning in the elementary school.

  8. Mechanistic study on the palladium(II)-catalyzed synthesis of 2,3-disubstituted indoles under aerobic conditions: anion effects and the development of a low-catalyst-loading process.

    PubMed

    Yao, Bo; Wang, Qian; Zhu, Jieping

    2014-09-15

    As a result of detailed mechanistic and kinetic studies, we have proposed that PdX2-catalyzed oxidative coupling of o-alkynylanilines 1 with terminal alkynes 2 under aerobic conditions is initiated by aminopalladation of 1 followed by ligand exchange of the resulting σ-indolylpalladium(II) complex with 2, reductive elimination and N-demethylation. Side reactions associated with intermediates on the way to 2,3-disubstituted indoles 3 were identified, and the roles of acetate and iodide in channeling the reaction towards the desired product were established. Based on kinetic and spectroscopic studies, the soluble iodide-ligated Pd(0) species was proposed to be the resting state of the catalyst and its oxidation to active Pd(II) species was the turnover-limiting step. Catalytic conditions with low loading of Pd(OAc)2 (0.0005 to 0.001 equiv) were subsequently developed.

  9. Dancing the aerobics ''hearing loss'' choreography

    NASA Astrophysics Data System (ADS)

    Pinto, Beatriz M.; Carvalho, Antonio P. O.; Gallagher, Sergio

    2002-11-01

    This paper presents an overview of gymnasiums' acoustic problems when used for aerobics exercises classes (and similar) with loud noise levels of amplified music. This type of gymnasium is usually a highly reverberant space, which is a consequence of a large volume surrounded by hard surfaces. A sample of five schools in Portugal was chosen for this survey. Noise levels in each room were measured using a precision sound level meter, and analyzed to calculate the standardized daily personal noise exposure levels (LEP,d). LEP,d values from 79 to 91 dB(A) were found to be typical values in this type of room, inducing a health risk for its occupants. The reverberation time (RT) values were also measured and compared with some European legal requirements (Portugal, France, and Belgium) for nearly similar situations. RT values (1 kHz) from 0.9 s to 2.8 s were found. These reverberation time values clearly differentiate between good and acoustically inadequate rooms. Some noise level and RT limits for this type of environment are given and suggestions for the improvement of the acoustical environment are shown. Significant reductions in reverberation time values and noise levels can be obtained by simple measures.

  10. A process for creating multimetric indices for large-scale aquatic surveys

    EPA Science Inventory

    Differences in sampling and laboratory protocols, differences in techniques used to evaluate metrics, and differing scales of calibration and application prohibit the use of many existing multimetric indices (MMIs) in large-scale bioassessments. We describe an approach to develop...

  11. Approaches to the Processing of Data from Large Aperture Acoustic Vertical Line Arrays

    DTIC Science & Technology

    1990-04-01

    50 3.4 GSM eigenrays across the very large vertical line array .............. 51 3.5 Conventional beam form er output...54 3.10 GSM eigenrays across the large vertical line array .................. 55 3.11 Conventional beam form er...GSM eigenrays at 162 km and at the sound axis .................... 80 4.8 ATLAS transmission loss versus range at 20 m depth ................ 81 4.9

  12. Monitoring operational and leachate characteristics of an aerobic simulated landfill bioreactor.

    PubMed

    Giannis, A; Makripodis, G; Simantiraki, F; Somara, M; Gidarakos, E

    2008-01-01

    Long-term biodegradation of MSW in an aerobic landfill bioreactor was monitored as a function of time during 510 days of operation. Operational characteristics such as air importation, temperature and leachate recirculation were monitored. The oxygen utilization rates and biodegradation of organic matter rates showed that aerobic biodegradation was feasible and appropriate to proceed in aerobic landfill bioreactor. Leachate analyses showed that the aerobic bioreactor could remove above 90% of chemical oxygen demand (COD) and close to 100% of biochemical oxygen demand (BOD5) from leachate. Ammonium (NH4+), nitrate (NO3-) and sulphate (SO4(2-)) concentrations of leachate samples were regularly measured. Results suggest that nitrification and denitrification occurred simultaneously, and the increase in nitrate did not reach the levels predicted stoichiometrically, suggesting that other processes were occurring. Leachate recirculation reduced the concentrations of heavy metals because of the effect of the high pH of the leachate, causing heavy metals to be retained by processes such as sorption on MSW, carbonate precipitation, and hydroxide precipitation. Furthermore, the compost derived from the aerobic biodegradation of the organic matter of MSW may be considered as soil improvement in the agricultural plant production. Bio-essays indicated that the ecotoxicity of leachate from the aerobic bioreactor was not toxic at the end of the experiment. Finally, after 510 days of degradation, waste settlement reached 26% mainly due to the compost of the organic matter.

  13. Conditioning and Aerobics for Older Americans.

    ERIC Educational Resources Information Center

    Hansen, Joyce

    1980-01-01

    A class designed for the maintenance and gradual improvement of senior citizens' physical fitness includes relaxation training, flexibility and stretching exercises, interval training activities (designed as a link between less strenuous exercise and more strenuous activities), and aerobic exercises. (CJ)

  14. The rise of oxygen and aerobic biochemistry.

    PubMed

    Saito, Mak A

    2012-01-11

    Analysis of conserved protein folding domains across extant genomes by Kim et al. in this issue of Structure provides insights into the timing of some of the earliest aerobic metabolisms to arise on Earth.

  15. Neuromodulation of Aerobic Exercise—A Review

    PubMed Central

    Heijnen, Saskia; Hommel, Bernhard; Kibele, Armin; Colzato, Lorenza S.

    2016-01-01

    Running, and aerobic exercise in general, is a physical activity that increasingly many people engage in but that also has become popular as a topic for scientific research. Here we review the available studies investigating whether and to which degree aerobic exercise modulates hormones, amino acids, and neurotransmitters levels. In general, it seems that factors such as genes, gender, training status, and hormonal status need to be taken into account to gain a better understanding of the neuromodular underpinnings of aerobic exercise. More research using longitudinal studies and considering individual differences is necessary to determine actual benefits. We suggest that, in order to succeed, aerobic exercise programs should include optimal periodization, prevent overtraining and be tailored to interindividual differences, including neuro-developmental and genetically-based factors. PMID:26779053

  16. The Energetics of Aerobic versus Anaerobic Respiration.

    ERIC Educational Resources Information Center

    Champion, Timothy D.; Schwenz, Richard W.

    1990-01-01

    Background information, laboratory procedures, and a discussion of the results of an experiment designed to investigate the difference in energy gained from the aerobic and anaerobic oxidation of glucose are presented. Sample experimental and calculated data are included. (CW)

  17. Aerobic and anaerobic ethanol production by Mucor circinelloides during submerged growth.

    PubMed

    Lübbehüsen, T L; Nielsen, J; McIntyre, M

    2004-02-01

    The dimorphic organism Mucor circinelloides is currently being investigated as a potential host for heterologous protein production. The production of ethanol on pentose and hexose sugars was studied in submerged batch cultivations to further the general knowledge of Mucor physiology, with a view to the minimisation or elimination of the by-product ethanol for future process design. Large amounts of ethanol were produced during aerobic growth on glucose under non-oxygen limiting conditions, which is indicative of M. circinelloides being a Crabtree-positive organism. Ethanol production on galactose or xylose was less significant. The response of the organism to increased ethanol concentrations, both as the sole carbon source and in the presence of a sugar, was investigated in terms of biomass formation and morphology.

  18. Finite Size Corrections to the Large Deviation Function of the Density in the One Dimensional Symmetric Simple Exclusion Process

    NASA Astrophysics Data System (ADS)

    Derrida, Bernard; Retaux, Martin

    2013-09-01

    The symmetric simple exclusion process is one of the simplest out-of-equilibrium systems for which the steady state is known. Its large deviation functional of the density has been computed in the past both by microscopic and macroscopic approaches. Here we obtain the leading finite size correction to this large deviation functional. The result is compared to the similar corrections for equilibrium systems.

  19. C4-Dicarboxylate Utilization in Aerobic and Anaerobic Growth.

    PubMed

    Unden, Gottfried; Strecker, Alexander; Kleefeld, Alexandra; Kim, Ok Bin

    2016-06-01

    C4-dicarboxylates and the C4-dicarboxylic amino acid l-aspartate support aerobic and anaerobic growth of Escherichia coli and related bacteria. In aerobic growth, succinate, fumarate, D- and L-malate, L-aspartate, and L-tartrate are metabolized by the citric acid cycle and associated reactions. Because of the interruption of the citric acid cycle under anaerobic conditions, anaerobic metabolism of C4-dicarboxylates depends on fumarate reduction to succinate (fumarate respiration). In some related bacteria (e.g., Klebsiella), utilization of C4-dicarboxylates, such as tartrate, is independent of fumarate respiration and uses a Na+-dependent membrane-bound oxaloacetate decarboxylase. Uptake of the C4-dicarboxylates into the bacteria (and anaerobic export of succinate) is achieved under aerobic and anaerobic conditions by different sets of secondary transporters. Expression of the genes for C4-dicarboxylate metabolism is induced in the presence of external C4-dicarboxylates by the membrane-bound DcuS-DcuR two-component system. Noncommon C4-dicarboxylates like l-tartrate or D-malate are perceived by cytoplasmic one-component sensors/transcriptional regulators. This article describes the pathways of aerobic and anaerobic C4-dicarboxylate metabolism and their regulation. The citric acid cycle, fumarate respiration, and fumarate reductase are covered in other articles and discussed here only in the context of C4-dicarboxylate metabolism. Recent aspects of C4-dicarboxylate metabolism like transport, sensing, and regulation will be treated in more detail. This article is an updated version of an article published in 2004 in EcoSal Plus. The update includes new literature, but, in particular, the sections on the metabolism of noncommon C4-dicarboxylates and their regulation, on the DcuS-DcuR regulatory system, and on succinate production by engineered E. coli are largely revised or new.

  20. Surface Structure of Aerobically Oxidized Diamond Nanocrystals

    DTIC Science & Technology

    2014-10-27

    distribution is unlimited. Surface Structure of Aerobically Oxidized Diamond Nanocrystals The views, opinions and/or findings contained in this report...2211 diamond nanocrystals, REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8. PERFORMING...Room 254, Mail Code 8725 New York, NY 10027 -7922 ABSTRACT Surface Structure of Aerobically Oxidized Diamond Nanocrystals Report Title We investigate

  1. Aerobic biodegradation of selected monoterpenes.

    PubMed

    Misra, G; Pavlostathis, S G; Perdue, E M; Araujo, R

    1996-07-01

    Batch experiments were conducted to assess the biotransformation potential of four hydrocarbon monoterpenes (d-limonene, alpha-pinene, gamma-terpinene, and terpinolene) and four alcohols (arbanol, linalool, plinol, and alpha-terpineol) under aerobic conditions at 23 degrees C. Both forest-soil extract and enriched cultures were used as inocula for the biodegradation experiments conducted first without, then with prior microbial acclimation to the monoterpenes tested. All four hydrocarbons and two alcohols were readily degraded. The increase in biomass and headspace CO2 concentrations paralleled the depletion of monoterpenes, thus confirming that terpene disappearance was the result of biodegradation accompanied by microbial growth and mineralization. Plinol resisted degradation in assays using inocula from diverse sources, while arbanol degraded very slowly. A significant fraction of d-limonene-derived carbon was accounted for as non-extractable, dissolved organic carbon, whereas terpineol exhibited a much higher degree of utilization. The rate and extent of monoterpene biodegradation were not significantly affected by the presence of dissolved natural organic matter.

  2. Aerobic catabolism of bile acids.

    PubMed Central

    Leppik, R A; Park, R J; Smith, M G

    1982-01-01

    Seventy-eight stable cultures obtained by enrichment on media containing ox bile or a single bile acid were able to utilize one or more bile acids, as well as components of ox bile, as primary carbon sources for growth. All isolates were obligate aerobes, and most (70) were typical (48) or atypical (22) Pseudomonas strains, the remainder (8) being gram-positive actinomycetes. Of six Pseudomonas isolates selected for further study, five produced predominantly acidic catabolites after growth on glycocholic acid, but the sixth, Pseudomonas sp. ATCC 31752, accumulated as the principal product a neutral steroid catabolite. Optimum growth of Pseudomonas sp. ATCC 31752 on ox bile occurred at pH 7 to 8 and from 25 to 30 degrees C. No additional nutrients were required to sustain good growth, but growth was stimulated by the addition of ammonium sulfate and yeast extract. Good growth was obtained with a bile solids content of 40 g/liter in shaken flasks. A near-theoretical yield of neutral steroid catabolites, comprising a major (greater than 50%) and three minor products, was obtained from fermentor growth of ATCC 31752 in 6.7 g of ox bile solids per liter. The possible commercial exploitation of these findings to produce steroid drug intermediates for the pharmaceutical industry is discussed. PMID:7149711

  3. TRW’s Ada Process Model for Incremental Development of Large Software Systems

    DTIC Science & Technology

    1990-01-01

    TRW’s Ada Process Model has proven to be key to the Command Center Processing and Display System-Replacement (CCPDS-R) project’s success to data in...developing over 3000,000 lines of Ada source code executing in a distributed VAX VMS environment. The Ada Process Model is, in simplest terms, a...software progress metrics. This paper provides an overview of the techniques and benefits of the Ada Process Model and describes some of the experience and

  4. Hydrological recurrence as a measure for large river basin classification and process understanding

    NASA Astrophysics Data System (ADS)

    Fernandez, R.; Sayama, T.

    2015-04-01

    Hydrological functions of river basins are summarized as collection, storage and discharge, which can be characterized by the dynamics of hydrological variables including precipitation, evaporation, storage and runoff. The temporal patterns of each variable can be indicators of the functionality of a basin. In this paper we introduce a measure to quantify the degree of similarity in intra-annual variations at monthly scale at different years for the four main variables. We introduce this measure under the term of recurrence and define it as the degree to which a monthly hydrological variable returns to the same state in subsequent years. The degree of recurrence in runoff is important not only for the management of water resources but also for the understanding of hydrologic processes, especially in terms of how the other three variables determine the recurrence in runoff. The main objective of this paper is to propose a simple hydrologic classification framework applicable to large basins at global scale based on the combinations of recurrence in the four variables using a monthly scale time series. We evaluate it with lagged autocorrelation (AC), fast Fourier transforms (FFT) and Colwell's indices of variables obtained from the EU-WATCH data set, which is composed of eight global hydrologic model (GHM) and land surface model (LSM) outputs. By setting a threshold to define high or low recurrence in the four variables, we classify each river basin into 16 possible classes. The overview of recurrence patterns at global scale suggested that precipitation is recurrent mainly in the humid tropics, Asian monsoon area and part of higher latitudes with an oceanic influence. Recurrence in evaporation was mainly dependent on the seasonality of energy availability, typically high in the tropics, temperate and sub-arctic regions. Recurrence in storage at higher latitudes depends on energy/water balances and snow, while that in runoff is mostly affected by the different

  5. Integrated observations of processes and products of large scale cratering experiments

    NASA Astrophysics Data System (ADS)

    Graettinger, A. H.; Sonder, I.; Valentine, G.; Ross, P.; White, J. D.; Taddeucci, J.; Zimanowski, B.; Lube, G.; Kueppers, U.; Bowman, D. C.

    2013-12-01

    Detailed analysis of volcanic craters and ballistic deposits can provide insight into eruption dynamics and evolution. As fully exposed craters and associated unmodified deposits are rarely preserved, the dynamics involved can only be inferred. Large-scale blast experiments conducted at the University at Buffalo Geohazards Field Station produced deposits from single and multiple subsurface explosions at individual craters, along with a range of observational data, and provide a unique opportunity to link dynamics with geologic structures and deposits. Meter-scale craters were produced through repeated blasts using chemical explosives in 15 cm thick strata constructed of compacted aggregates (e.g. sands and gravels). Each experiment had 1-3 individual explosions with the same epicenter to form a single crater, with a total of 12 blasts and five craters. Three craters were produced through a series of shallow blasts (34-75 cm depth, six blasts) and two additional craters were produced by deeper blasts (75-100 cm, six blasts). The experiments successfully reproduced crater structures similar to those of maar volcanoes, which are the product of one or more subsurface explosions resulting from the interaction of magma with groundwater. Deep explosion tests successfully reproduced mixing and structures similar to maar-diatremes. The ballistics produced were collected in sample boxes up to 18 m from the blast center. The pits were later excavated and the vertical structures and deposits were described and sampled. Deposits can be described as bedded-diatreme (fallback/inter-crater deposits), unbedded diatreme (disturbed subsurface material), tephra ring (debris on the pre-blast surface) and distal extra-crater deposits. Granulometry and componentry were acquired for all samples. The diatreme structures and deposit componentry were interpreted using high-speed video recordings of the blasts. A comparison of ballistic source depth and collection location revealed the

  6. Thermal analysis of the growth process of synthetic diamond in the large volume cubic press apparatus with large deformation of high pressure cell

    NASA Astrophysics Data System (ADS)

    Zhang, Qingchao; Li, Rui; Gu, Xue; Qin, Jieming; Jia, Xiaopeng; Ma, Hongan

    2015-06-01

    The temperature-field in diamond synthesis cell was simulated by a finite element method. A three-dimensional model of the China-type cubic press with large deformation of the synthesis cell was established successfully, which has been verified by situ measurements of synthesis cell. In addition, the distributions of temperature and its gradient in the synthesis sample were described. We found there is a large temperature drop in the synthesis sample, which brings some uncertainties in a synthesis process, such as the phenomenon of "wasteland, on which there is no nucleation and growth of diamond". Furthermore, the formation mechanism of wasteland was studied in detail. It indicates that the wasteland is inevitably exists in the synthesis sample, the distribution of growth region of the diamond with hex-octahedral is move to the center of the synthesis sample from near the heater as the power increasing, and the growth conditions of high quality diamond is locate at the center of the synthesis sample. This work can offer suggestion and advice to the development and optimization of a diamond production process.

  7. Large-scale production of diesel-like biofuels - process design as an inherent part of microorganism development.

    PubMed

    Cuellar, Maria C; Heijnen, Joseph J; van der Wielen, Luuk A M

    2013-06-01

    Industrial biotechnology is playing an important role in the transition to a bio-based economy. Currently, however, industrial implementation is still modest, despite the advances made in microorganism development. Given that the fuels and commodity chemicals sectors are characterized by tight economic margins, we propose to address overall process design and efficiency at the start of bioprocess development. While current microorganism development is targeted at product formation and product yield, addressing process design at the start of bioprocess development means that microorganism selection can also be extended to other critical targets for process technology and process scale implementation, such as enhancing cell separation or increasing cell robustness at operating conditions that favor the overall process. In this paper we follow this approach for the microbial production of diesel-like biofuels. We review current microbial routes with both oleaginous and engineered microorganisms. For the routes leading to extracellular production, we identify the process conditions for large scale operation. The process conditions identified are finally translated to microorganism development targets. We show that microorganism development should be directed at anaerobic production, increasing robustness at extreme process conditions and tailoring cell surface properties. All the same time, novel process configurations integrating fermentation and product recovery, cell reuse and low-cost technologies for product separation are mandatory. This review provides a state-of-the-art summary of the latest challenges in large-scale production of diesel-like biofuels.

  8. The TRIPSE: A Process-Oriented Exam for Large Undergraduate Classes

    ERIC Educational Resources Information Center

    Nastos, Stash; Rangachari, P. K.

    2013-01-01

    The TRIPSE (tri-partite problem solving exercise), a process-oriented exam that mimics the scientific process, was used previously in small classes (15-25). Provided limited data, students frame explanations and design experimental tests that they later revise with additional information. Our 6-year experience using it with larger numbers…

  9. Depth gradients in food web processes linking large lake habitats -presentation

    EPA Science Inventory

    In large lakes around the world, shifts in ecological communities are often associated with water depth. This suggests that there may be concomitant changes in patterns of resource allocation. Using Lake Superior as an example, we explored this idea through stable isotope analyse...

  10. On the Large Deviation Rate Function for the Empirical Measures of Reversible Jump Markov Processes

    DTIC Science & Technology

    2013-09-12

    function. Ann. Probab., 13:342�362, 1985. [10] Walter Rudin . Functional Analysis. McGraw-Hill, New York, 1991. [11] D.W. Stroock. An Introduction to the Theory of Large Deviations. Springer- Verlag, New York, 1984. 36 39

  11. Large Aircraft Robotic Paint Stripping (LARPS) system and the high pressure water process

    NASA Astrophysics Data System (ADS)

    See, David W.; Hofacker, Scott A.; Stone, M. Anthony; Harbaugh, Darcy

    1993-03-01

    The aircraft maintenance industry is beset by new Environmental Protection Agency (EPA) guidelines on air emissions, Occupational Safety and Health Administration (OSHA) standards, dwindling labor markets, Federal Aviation Administration (FAA) safety guidelines, and increased operating costs. In light of these factors, the USAF's Wright Laboratory Manufacturing Technology Directorate and the Aircraft Division of the Oklahoma City Air Logistics Center initiated a MANTECH/REPTECH effort to automate an alternate paint removal method and eliminate the current manual methylene chloride chemical stripping methods. This paper presents some of the background and history of the LARPS program, describes the LARPS system, documents the projected operational flow, quantifies some of the projected system benefits and describes the High Pressure Water Stripping Process. Certification of an alternative paint removal method to replace the current chemical process is being performed in two phases: Process Optimization and Process Validation. This paper also presents the results of the Process Optimization for metal substrates. Data on the coating removal rate, residual stresses, surface roughness, preliminary process envelopes, and technical plans for process Validation Testing will be discussed.

  12. Aerobic Microbial Respiration In Oceanic Oxygen Minimum Zones

    PubMed Central

    Kalvelage, Tim; Lavik, Gaute; Jensen, Marlene M.; Revsbech, Niels Peter; Löscher, Carolin; Schunck, Harald; Desai, Dhwani K.; Hauss, Helena; Kiko, Rainer; Holtappels, Moritz; LaRoche, Julie; Schmitz, Ruth A.; Graco, Michelle I.; Kuypers, Marcel M. M.

    2015-01-01

    Oxygen minimum zones are major sites of fixed nitrogen loss in the ocean. Recent studies have highlighted the importance of anaerobic ammonium oxidation, anammox, in pelagic nitrogen removal. Sources of ammonium for the anammox reaction, however, remain controversial, as heterotrophic denitrification and alternative anaerobic pathways of organic matter remineralization cannot account for the ammonium requirements of reported anammox rates. Here, we explore the significance of microaerobic respiration as a source of ammonium during organic matter degradation in the oxygen-deficient waters off Namibia and Peru. Experiments with additions of double-labelled oxygen revealed high aerobic activity in the upper OMZs, likely controlled by surface organic matter export. Consistently observed oxygen consumption in samples retrieved throughout the lower OMZs hints at efficient exploitation of vertically and laterally advected, oxygenated waters in this zone by aerobic microorganisms. In accordance, metagenomic and metatranscriptomic analyses identified genes encoding for aerobic terminal oxidases and demonstrated their expression by diverse microbial communities, even in virtually anoxic waters. Our results suggest that microaerobic respiration is a major mode of organic matter remineralization and source of ammonium (~45-100%) in the upper oxygen minimum zones, and reconcile hitherto observed mismatches between ammonium producing and consuming processes therein. PMID:26192623

  13. Aerobic Microbial Respiration In Oceanic Oxygen Minimum Zones.

    PubMed

    Kalvelage, Tim; Lavik, Gaute; Jensen, Marlene M; Revsbech, Niels Peter; Löscher, Carolin; Schunck, Harald; Desai, Dhwani K; Hauss, Helena; Kiko, Rainer; Holtappels, Moritz; LaRoche, Julie; Schmitz, Ruth A; Graco, Michelle I; Kuypers, Marcel M M

    2015-01-01

    Oxygen minimum zones are major sites of fixed nitrogen loss in the ocean. Recent studies have highlighted the importance of anaerobic ammonium oxidation, anammox, in pelagic nitrogen removal. Sources of ammonium for the anammox reaction, however, remain controversial, as heterotrophic denitrification and alternative anaerobic pathways of organic matter remineralization cannot account for the ammonium requirements of reported anammox rates. Here, we explore the significance of microaerobic respiration as a source of ammonium during organic matter degradation in the oxygen-deficient waters off Namibia and Peru. Experiments with additions of double-labelled oxygen revealed high aerobic activity in the upper OMZs, likely controlled by surface organic matter export. Consistently observed oxygen consumption in samples retrieved throughout the lower OMZs hints at efficient exploitation of vertically and laterally advected, oxygenated waters in this zone by aerobic microorganisms. In accordance, metagenomic and metatranscriptomic analyses identified genes encoding for aerobic terminal oxidases and demonstrated their expression by diverse microbial communities, even in virtually anoxic waters. Our results suggest that microaerobic respiration is a major mode of organic matter remineralization and source of ammonium (~45-100%) in the upper oxygen minimum zones, and reconcile hitherto observed mismatches between ammonium producing and consuming processes therein.

  14. Stabilisation of microalgae: Iodine mobilisation under aerobic and anaerobic conditions.

    PubMed

    Han, Wei; Clarke, William; Pratt, Steven

    2015-10-01

    Mobilisation of iodine during microalgae stabilisation was investigated, with the view of assessing the potential of stabilised microalgae as an iodine-rich fertiliser. An iodine-rich waste microalgae (0.35 ± 0.05 mg I g(-1) VS(added)) was stabilised under aerobic and anaerobic conditions. Iodine mobilisation was linearly correlated with carbon emission, indicating iodine was in the form of organoiodine. Comparison between iodine and nitrogen mobilisation relative to carbon emission indicated that these elements were, at least in part, housed separately within the cells. After stabilisation, there were 0.22 ± 0.05 and 0.19 ± 0.01 mg g(-1) VS(added) iodine remaining in the solid in the aerobic and anaerobic processed material respectively, meaning 38 ± 5.0% (aerobic) and 50 ± 8.6% (anaerobic) of the iodine were mobilised, and consequently lost from the material. The iodine content of the stabilised material is comparable to the iodine content of some seaweed fertilisers, and potentially satisfies an efficient I-fertilisation dose.

  15. Dissolving decision making? Models and their roles in decision-making processes and policy at large.

    PubMed

    Zeiss, Ragna; van Egmond, Stans

    2014-12-01

    This article studies the roles three science-based models play in Dutch policy and decision making processes. Key is the interaction between model construction and environment. Their political and scientific environments form contexts that shape the roles of models in policy decision making. Attention is paid to three aspects of the wider context of the models: a) the history of the construction process; b) (changes in) the political and scientific environments; and c) the use in policy processes over longer periods of time. Models are more successfully used when they are constructed in a stable political and scientific environment. Stability and certainty within a scientific field seems to be a key predictor for the usefulness of models for policy making. The economic model is more disputed than the ecology-based model and the model that has its theoretical foundation in physics and chemistry. The roles models play in policy processes are too complex to be considered as straightforward technocratic powers.

  16. Integrated Anaerobic-Aerobic Biodegradation of Multiple Contaminants Including Chlorinated Ethylenes, Benzene, Toluene, and Dichloromethane.

    PubMed

    Yoshikawa, Miho; Zhang, Ming; Toyota, Koki

    2017-01-01

    Complete bioremediation of soils containing multiple volatile organic compounds (VOCs) remains a challenge. To explore the possibility of complete bioremediation through integrated anaerobic-aerobic biodegradation, laboratory feasibility tests followed by alternate anaerobic-aerobic and aerobic-anaerobic biodegradation tests were performed. Chlorinated ethylenes, including tetrachloroethylene (PCE), trichloroethylene (TCE), cis-dichloroethylene (cis-DCE), and vinyl chloride (VC), and dichloromethane (DCM) were used for anaerobic biodegradation, whereas benzene, toluene, and DCM were used for aerobic biodegradation tests. Microbial communities involved in the biodegradation tests were analyzed to characterize the major bacteria that may contribute to biodegradation. The results demonstrated that integrated anaerobic-aerobic biodegradation was capable of completely degrading the seven VOCs with initial concentration of each VOC less than 30 mg/L. Benzene and toluene were degraded within 8 days, and DCM was degraded within 20 to 27 days under aerobic conditions when initial oxygen concentrations in the headspaces of test bottles were set to 5.3% and 21.0%. Dehalococcoides sp., generally considered sensitive to oxygen, survived aerobic conditions for 28 days and was activated during the subsequent anaerobic biodegradation. However, degradation of cis-DCE was suppressed after oxygen exposure for more than 201 days, suggesting the loss of viability of Dehalococcoides sp., as they are the only known anaerobic bacteria that can completely biodegrade chlorinated ethylenes to ethylene. Anaerobic degradation of DCM following previous aerobic degradation was complete, and yet-unknown microbes may be involved in the process. The findings may provide a scientific and practical basis for the complete bioremediation of multiple contaminants in situ and a subject for further exploration.

  17. Aerobic exercise increases hippocampal volume and improves memory in multiple sclerosis: preliminary findings.

    PubMed

    Leavitt, V M; Cirnigliaro, C; Cohen, A; Farag, A; Brooks, M; Wecht, J M; Wylie, G R; Chiaravalloti, N D; DeLuca, J; Sumowski, J F

    2014-01-01

    Multiple sclerosis leads to prominent hippocampal atrophy, which is linked to memory deficits. Indeed, 50% of multiple sclerosis patients suffer memory impairment, with negative consequences for quality of life. There are currently no effective memory treatments for multiple sclerosis either pharmacological or behavioral. Aerobic exercise improves memory and promotes hippocampal neurogenesis in nonhuman animals. Here, we investigate the benefits of aerobic exercise in memory-impaired multiple sclerosis patients. Pilot data were collected from two ambulatory, memory-impaired multiple sclerosis participants randomized to non-aerobic (stretching) and aerobic (stationary cycling) conditions. The following baseline/follow-up measurements were taken: high-resolution MRI (neuroanatomical volumes), fMRI (functional connectivity), and memory assessment. Intervention was 30-minute sessions 3 times per week for 3 months. Aerobic exercise resulted in 16.5% increase in hippocampal volume and 53.7% increase in memory, as well as increased hippocampal resting-state functional connectivity. Improvements were specific, with no comparable changes in overall cerebral gray matter (+2.4%), non-hippocampal deep gray matter structures (thalamus, caudate: -4.0%), or in non-memory cognitive functioning (executive functions, processing speed, working memory: changes ranged from -11% to +4%). Non-aerobic exercise resulted in relatively no change in hippocampal volume (2.8%) or memory (0.0%), and no changes in hippocampal functional connectivity. This is the first evidence for aerobic exercise to increase hippocampal volume and connectivity and improve memory in multiple sclerosis. Aerobic exercise represents a cost-effective, widely available, natural, and self-administered treatment with no adverse side effects that may be the first effective memory treatment for multiple sclerosis patients.

  18. Characteristics of a Novel Aerobic Denitrifying Bacterium, Enterobacter cloacae Strain HNR.

    PubMed

    Guo, Long-Jie; Zhao, Bin; An, Qiang; Tian, Meng

    2016-03-01

    A novel aerobic denitrifier strain HNR, isolated from activated sludge, was identified as Enterobacter cloacae by16S rRNA sequencing analysis. Glucose was considered as the most favorable C-source for strain HNR. The logistic equation well described the bacterial growth, yielding a maximum growth rate (μmax) of 0.283 h(-1) with an initial NO3 (-)-N concentration of 110 mg/L. Almost all NO3 (-)-N was removed aerobically within 30 h with an average removal rate of 4.58 mg N L(-1) h(-1). Nitrogen balance analysis revealed that proximately 70.8 % of NO3 (-)-N was removed as gas products and only 20.7 % was transformed into biomass. GC-MS result indicates that N2 was the end product of aerobic denitrification. The enzyme activities of nitrate reductase and nitrite reductase, which are related to the process of aerobic denitrification, were 0.0688 and 0.0054 U/mg protein, respectively. Thus, the aerobic denitrification of reducing NO3 (-) to N2 by strain HNR was demonstrated. The optimal conditions for nitrate removal were C/N ratio 13, pH value 8, shaking speed 127 rpm and temperature 30 °C. These findings show that E. cloacae strain HNR has a potential application on wastewater treatment to achieve nitrate removal under aerobic conditions.

  19. Proteome analysis of aerobic and fermentative metabolism in Rhizobium etli CE3.

    PubMed

    Encarnación, Sergio; Guzmán, Yudith; Dunn, Michael F; Hernández, Magdalena; del Carmen Vargas, Maria; Mora, Jaime

    2003-06-01

    Rhizobium etli undergoes a transition from an aerobic to a fermentative metabolism during successive subcultures in minimal medium. This metabolic transition does not occur in cells subcultured in rich medium, or in minimal medium containing either biotin or thiamine. In this report, we characterize the aerobic and fermentative metabolism of R. etli using proteome analysis. According to their synthesis patterns in response to aerobic (rich medium, minimal medium with biotin or minimal medium with thiamine) or fermentative (minimal medium without supplements) growth conditions, proteins were assigned to five different classes: (i) proteins produced only in aerobic conditions (e.g., catalase-peroxidase KatG and the E2 component of pyruvate dehydrogenase); (ii) protein produced under both conditions but strongly induced in aerobic metabolism (e.g., malate dehydrogenase and the succinyl-CoA synthetase beta subunit); (iii) proteins that were induced equally under all conditions tested (e.g., AniA, DnaK, and GroEL); (iv) proteins downregulated during aerobic metabolism, and (v) proteins specific to only one of the conditions analyzed. Northern blotting studies of katG expression confirmed the proteome data for this protein. The negative regulation of carbon metabolism proteins observed in fermentative metabolism is consistent with the drastic physiological changes which occur during this process.

  20. Automation of Survey Data Processing, Documentation and Dissemination: An Application to Large-Scale Self-Reported Educational Survey.

    ERIC Educational Resources Information Center

    Shim, Eunjae; Shim, Minsuk K.; Felner, Robert D.

    Automation of the survey process has proved successful in many industries, yet it is still underused in educational research. This is largely due to the facts (1) that number crunching is usually carried out using software that was developed before information technology existed, and (2) that the educational research is to a great extent trapped…

  1. Experimental investigation of precision grinding oriented to achieve high process efficiency for large and middle-scale optic

    NASA Astrophysics Data System (ADS)

    Li, Ping; Jin, Tan; Guo, Zongfu; Lu, Ange; Qu, Meina

    2016-10-01

    High efficiency machining of large precision optical surfaces is a challenging task for researchers and engineers worldwide. The higher form accuracy and lower subsurface damage helps to significantly reduce the cycle time for the following polishing process, save the cost of production, and provide a strong enabling technology to support the large telescope and laser energy fusion projects. In this paper, employing an Infeed Grinding (IG) mode with a rotary table and a cup wheel, a multi stage grinding process chain, as well as precision compensation technology, a Φ300mm diameter plano mirror is ground by the Schneider Surfacing Center SCG 600 that delivers a new level of quality and accuracy when grinding such large flats. Results show a PV form error of Pt<2 μm, the surface roughness Ra<30 nm and Rz<180 nm, with subsurface damage <20 μm, and a material removal rates of up to 383.2 mm3/s.

  2. E-health, phase two: the imperative to integrate process automation with communication automation for large clinical reference laboratories.

    PubMed

    White, L; Terner, C

    2001-01-01

    The initial efforts of e-health have fallen far short of expectations. They were buoyed by the hype and excitement of the Internet craze but limited by their lack of understanding of important market and environmental factors. E-health now recognizes that legacy systems and processes are important, that there is a technology adoption process that needs to be followed, and that demonstrable value drives adoption. Initial e-health transaction solutions have targeted mostly low-cost problems. These solutions invariably are difficult to integrate into existing systems, typically requiring manual interfacing to supported processes. This limitation in particular makes them unworkable for large volume providers. To meet the needs of these providers, e-health companies must rethink their approaches, appropriately applying technology to seamlessly integrate all steps into existing business functions. E-automation is a transaction technology that automates steps, integration of steps, and information communication demands, resulting in comprehensive automation of entire business functions. We applied e-automation to create a billing management solution for clinical reference laboratories. Large volume, onerous regulations, small margins, and only indirect access to patients challenge large laboratories' billing departments. Couple these problems with outmoded, largely manual systems and it becomes apparent why most laboratory billing departments are in crisis. Our approach has been to focus on the most significant and costly problems in billing: errors, compliance, and system maintenance and management. The core of the design relies on conditional processing, a "universal" communications interface, and ASP technologies. The result is comprehensive automation of all routine processes, driving out errors and costs. Additionally, compliance management and billing system support and management costs are dramatically reduced. The implications of e-automated processes can extend

  3. Aerobic Excercise and Research Opportunities to Benefit Impaired Children. (Project AEROBIC). Final Report.

    ERIC Educational Resources Information Center

    Idaho Univ., Moscow.

    The final report summarizes accomplishments of Project AEROBIC (Aerobic Exercise and Research Opportunities to Benefit Impaired Children), which provided a physical education exercise program for severely, profoundly, and multiply handicapped children aged 10-21. Activities are outlined for the 3 year period and include modification of exercise…

  4. Effect of long term anaerobic and intermittent anaerobic/aerobic starvation on aerobic granules.

    PubMed

    Pijuan, Maite; Werner, Ursula; Yuan, Zhiguo

    2009-08-01

    The effect of long term anaerobic and intermittent anaerobic/aerobic starvation on the structure and activity of aerobic granules was studied. Aerobic granular sludge treating abattoir wastewater and achieving high levels of nutrient removal was subjected to 4-5 week starvation under anaerobic and intermittent anaerobic/aerobic conditions. Microscopic pictures of granules at the beginning of the starvation period presented a round and compact surface morphology with a much defined external perimeter. Under both starvation conditions, the morphology changed at the end of starvation with the external border of the granules surrounded by floppy materials. The loss of granular compactness was faster and more pronounced under anaerobic/aerobic starvation conditions. The release of Ca(2+) at the onset of anaerobic/aerobic starvation suggests a degradation of extracellular polymeric substances. The activity of ammonia oxidizing bacteria was reduced by 20 and 36% during anaerobic and intermittent anaerobic/aerobic starvation, respectively. When fresh wastewater was reintroduced, the granules recovered their initial morphology within 1 week of normal operation and the nutrient removal activity recovered fully in 3 weeks. The results show that both anaerobic and intermittent anaerobic/aerobic conditions are suitable for maintaining granule structure and activity during starvation.

  5. Large-scale Analysis of Counseling Conversations: An Application of Natural Language Processing to Mental Health

    PubMed Central

    Althoff, Tim; Clark, Kevin; Leskovec, Jure

    2016-01-01

    Mental illness is one of the most pressing public health issues of our time. While counseling and psychotherapy can be effective treatments, our knowledge about how to conduct successful counseling conversations has been limited due to lack of large-scale data with labeled outcomes of the conversations. In this paper, we present a large-scale, quantitative study on the discourse of text-message-based counseling conversations. We develop a set of novel computational discourse analysis methods to measure how various linguistic aspects of conversations are correlated with conversation outcomes. Applying techniques such as sequence-based conversation models, language model comparisons, message clustering, and psycholinguistics-inspired word frequency analyses, we discover actionable conversation strategies that are associated with better conversation outcomes.

  6. Computer-Controlled Cylindrical Polishing Process for Large X-Ray Mirror Mandrels

    NASA Technical Reports Server (NTRS)

    Khan, Gufran S.; Gubarev, Mikhail; Speegle, Chet; Ramsey, Brian

    2010-01-01

    We are developing high-energy grazing incidence shell optics for hard-x-ray telescopes. The resolution of a mirror shells depends on the quality of cylindrical mandrel from which they are being replicated. Mid-spatial-frequency axial figure error is a dominant contributor in the error budget of the mandrel. This paper presents our efforts to develop a deterministic cylindrical polishing process in order to keep the mid-spatial-frequency axial figure errors to a minimum. Simulation software is developed to model the residual surface figure errors of a mandrel due to the polishing process parameters and the tools used, as well as to compute the optical performance of the optics. The study carried out using the developed software was focused on establishing a relationship between the polishing process parameters and the mid-spatial-frequency error generation. The process parameters modeled are the speeds of the lap and the mandrel, the tool s influence function, the contour path (dwell) of the tools, their shape and the distribution of the tools on the polishing lap. Using the inputs from the mathematical model, a mandrel having conical approximated Wolter-1 geometry, has been polished on a newly developed computer-controlled cylindrical polishing machine. The preliminary results of a series of polishing experiments demonstrate a qualitative agreement with the developed model. We report our first experimental results and discuss plans for further improvements in the polishing process. The ability to simulate the polishing process is critical to optimize the polishing process, improve the mandrel quality and significantly reduce the cost of mandrel production

  7. Combination of ozonation with conventional aerobic oxidation for distillery wastewater treatment.

    PubMed

    Sangave, Preeti C; Gogate, Parag R; Pandit, Aniruddha B

    2007-05-01

    Laboratory-scale experiments were conducted in order to investigate the effect of ozone as pre-aerobic treatment and post-aerobic treatment for the treatment of the distillery wastewater. The degradation of the pollutants present in distillery spent wash was carried out by ozonation, aerobic biological degradation processes alone and by using the combinations of these two processes to investigate the synergism between the two modes of wastewater treatment and with the aim of reducing the overall treatment costs. Pollutant removal efficiency was followed by means of global parameters directly related to the concentration of organic compounds in those effluents: chemical oxygen demand (COD) and the color removal efficiency in terms of absorbance of the sample at 254 nm. Ozone was found to be effective in bringing down the COD (up to 27%) during the pretreatment step itself. In the combined process, pretreatment of the effluent led to enhanced rates of subsequent biological oxidation step, almost 2.5 times increase in the initial oxidation rate has been observed. Post-aerobic treatment with ozone led to further removal of COD along with the complete discoloration of the effluent. The integrated process (ozone-aerobic oxidation-ozone) achieved approximately 79% COD reduction along with discoloration of the effluent sample as compared to 34.9% COD reduction for non-ozonated sample, over a similar treatment period.

  8. Resin Film Infusion (RFI) Process Modeling for Large Transport Aircraft Wing Structures

    NASA Technical Reports Server (NTRS)

    Knott, Tamara W.; Loos, Alfred C.

    2000-01-01

    Resin film infusion (RFI) is a cost-effective method for fabricating stiffened aircraft wing structures. The RFI process lends itself to the use of near net shape textile preforms manufactured through a variety of automated textile processes such as knitting and braiding. Often, these advanced fiber architecture preforms have through-the-thickness stitching for improved damage tolerance and delamination resistance. The challenge presently facing RFI is to refine the process to ensure complete infiltration and cure of a geometrically complex shape preform with the high fiber volume fraction needed for structural applications. An accurate measurement of preform permeability is critical for successful modeling of the RFI resin infiltration process. Small changes in the permeability can result in very different infiltration behavior and times. Therefore, it is important to accurately measure the permeabilities of the textile preforms used in the RFI process. The objective of this investigation was to develop test methods that can be used to measure the compaction behavior and permeabilities of high fiber volume fraction, advanced fiber architecture textile preforms. These preforms are often highly compacted due to through-the-thickness stitching used to improve damage tolerance. Test fixtures were designed and fabricated and used to measure both transverse and in-plane permeabilities. The fixtures were used to measure the permeabilities of multiaxial warp knit and triaxial braided preforms at fiber volume fractions from 55% to 65%. In addition, the effects of stitching characteristics, thickness, and batch variability on permeability and compaction behavior were investigated.

  9. Large-scale monoclonal antibody purification by continuous chromatography, from process design to scale-up.

    PubMed

    Girard, Valérie; Hilbold, Nicolas-Julian; Ng, Candy K S; Pegon, Laurence; Chahim, Wael; Rousset, Fabien; Monchois, Vincent

    2015-11-10

    The development and optimization of a purification process of monoclonal antibodies based on two continuous chromatography steps for capture and intermediate purification are presented. The two chromatography steps were individually optimized using either batch chromatography or sequential multicolumn chromatography (SMCC). Proprietary simulation software was used to optimize SMCC and to evaluate the potential gains compared with batch chromatography. The SMCC recipes provided by the simulation software were evaluated experimentally. A good correlation was found between the simulated results and experimental observations. Significant gains were observed on the productivity, buffer consumption and the volume of resin required for SMCC over batch chromatography. Based on these results, a chained process from the capture to polishing steps was implemented. This chained process demonstrated significantly better performance compared with the batch equivalent while satisfying the specifications. The expected positive impact provided by implementing continuous chromatography is also discussed.

  10. Large-Scale Testing of Treatment Processes as Alternatives to Ballast Exchange

    DTIC Science & Technology

    2003-09-01

    or P ha eo ph yt in ( µg L -1 ) Chlorophyll a Phaeophytin Figure 7. Effect of hydrocyclone, screen and UV unit processes on total phytoplankton ...varying turbidities on total phytoplankton population. 0.00 0.20 0.40 0.60 0.80 25,000 40,000 60,000 UV Dose (µW s cm-2) Ph yt op la nk to n...r P ha eo ph yt in ( µ g L- 1 ) Chlorophyll a Phaeophytin Figure 19. Effect of screen and UV unit processes on total phytoplankton population at

  11. Could petroleum biodegradation be a joint achievement of aerobic and anaerobic microrganisms in deep sea reservoirs?

    PubMed Central

    2011-01-01

    Several studies suggest that petroleum biodegradation can be achieved by either aerobic or anaerobic microorganisms, depending on oxygen input or other electron acceptors and appropriate nutrients. Evidence from in vitro experiments with samples of petroleum formation water and oils from Pampo Field indicate that petroleum biodegradation is more likely to be a joint achievement of both aerobic and anaerobic bacterial consortium, refining our previous observations of aerobic degradation. The aerobic consortium depleted, in decreasing order, hydrocarbons > hopanes > steranes > tricyclic terpanes while the anaerobic consortium depleted hydrocarbons > steranes > hopanes > tricyclic terpanes. The oxygen content of the mixed consortia was measured from time to time revealing alternating periods of microaerobicity (O2 ~0.8 mg.L-1) and of aerobicity (O2~6.0 mg.L-1). In this experiment, the petroleum biodegradation changed from time to time, alternating periods of biodegradation similar to the aerobic process and periods of biodegradation similar to the anaerobic process. The consortia showed preferences for metabolizing hydrocarbons > hopanes > steranes > tricyclic terpanes during a 90-day period, after which this trend changed and steranes were more biodegraded than hopanes. The analysis of aerobic oil degrading microbiota by the 16S rRNA gene clone library detected the presence of Bacillus, Brevibacterium, Mesorhizobium and Achromobacter, and the analysis of the anaerobic oil degrading microbiota using the same technique detected the presence of Bacillus and Acinetobacter (facultative strains). In the mixed consortia Stenotrophomonas, Brevibacterium, Bacillus, Rhizobium, Achromobacter and 5% uncultured bacteria were detected. This is certainly a new contribution to the study of reservoir biodegradation processes, combining two of the more important accepted hypotheses. PMID:22196374

  12. GLAST: Exploring Nature's Highest Energy Processes with the Gamma-ray Large Area Space Telescope

    NASA Technical Reports Server (NTRS)

    Digel, Seth; Myers, J. D.; White, Nicholas E. (Technical Monitor)

    2001-01-01

    The Gamma-ray Large Area Space Telescope (GLAST) is an international and multi-agency space mission that will study the cosmos in the energy range 10 keV-300 GeV. Several successful exploratory missions in gamma-ray astronomy led to the Energetic Gamma Ray Experiment Telescope (EGRET) instrument on the Compton Gamma Ray Observatory (CGRO). Launched in 1991, EGRET made the first complete survey of the sky in the 30 MeV-10 GeV range. EGRET showed the high-energy gamma-ray sky to be surprisingly dynamic and diverse, with sources ranging from the sun and moon to massive black holes at large redshifts. Most of the gamma-ray sources detected by EGRET remain unidentified. In light of the discoveries with EGRET, the great potential of the next generation gamma-ray telescope can be appreciated. GLAST will have an imaging gamma-ray telescope vastly more capable than instruments flown previously, as well as a secondary instrument to augment the study of gamma-ray bursts. The main instrument, the Large Area Telescope (LAT), will have superior area, angular resolution, field of view, and deadtime that together will provide a factor of 30 or more advance in sensitivity, as well as provide capability for study of transient phenomena. The GLAST Burst Monitor (GBM) will have a field of view several times larger than the LAT and will provide spectral coverage of gamma-ray bursts that extends from the lower limit of the LAT down to 10 keV. The basic parameters of the GBM are compared to those of the Burst and Transient Source Experiment (BATSE) instrument on CGRO in Table 1-2. With the LAT and GBM, GLAST will be a flexible observatory for investigating the great range of astrophysical phenomena best studied in high-energy gamma rays. NASA plans to launch GLAST in late 2005.

  13. The Large Laboratory Course: Organize It to Parallel Industrial Process Development.

    ERIC Educational Resources Information Center

    Eckert, Roger E.; Ybarra, Robert M.

    1988-01-01

    Describes a senior level chemical engineering course at Purdue University that parallels an industrial process development department. Stresses the course organization, manager-engineer contract, evaluation of students, course evaluation, and gives examples of course improvements made during the course. (CW)

  14. Plasma Processing of Large Surfaces with Application to SRF Cavity Modification

    SciTech Connect

    Upadhyay, Janardan; Popovic, Svetozar; Vuskovic, Leposova; Im, Do; Valente, Anne-Marie; Phillips, H

    2013-09-01

    Plasma based surface modifications of SRF cavities present promising alternatives to the wet etching technology currently applied. To understand and characterize the plasma properties and chemical kinetics of plasma etching processes inside a single cell cavity, we have built a specially-designed cylindrical cavity with 8 observation ports. These ports can be used for holding niobium samples and diagnostic purposes simultaneously. Two frequencies (13.56 MHz and 2.45 GHz) of power source are used for different pressure, power and gas compositions. The plasma parameters were evaluated by a Langmuir probe and by an optical emission spectroscopy technique based on the relative intensity of two Ar 5p-4s lines at 419.8 and 420.07 nm. Argon 5p-4s transition is chosen to determine electron temperature in order to optimize parameters for plasma processing. Chemical kinetics of the process was observed using real-time mass spectroscopy. The effect of these parameters on niobium surface would be measured, presented at this conference, and used as guidelines for optimal design of SRF etching process.

  15. Simulation of mass storage systems operating in a large data processing facility

    NASA Technical Reports Server (NTRS)

    Holmes, R.

    1972-01-01

    A mass storage simulation program was written to aid system designers in the design of a data processing facility. It acts as a tool for measuring the overall effect on the facility of on-line mass storage systems, and it provides the means of measuring and comparing the performance of competing mass storage systems. The performance of the simulation program is demonstrated.

  16. Phase Transition for the Large-Dimensional Contact Process with Random Recovery Rates on Open Clusters

    NASA Astrophysics Data System (ADS)

    Xue, Xiaofeng

    2016-12-01

    In this paper we are concerned with the contact process with random recovery rates on open clusters of bond percolation on Z^d. Let ξ be a random variable such that P(ξ ≥ 1)=1, which ensures E1/ξ <+∞, then we assign i. i. d. copies of ξ on the vertices as the random recovery rates. Assuming that each edge is open with probability p and the infection can only spread through the open edges, then we obtain that limsup _{d→ +∞}λ _d≤ λ _c=1/pE{1}/{ξ}, where λ _d is the critical value of the process on Z^d, i.e., the maximum of the infection rates with which the infection dies out with probability one when only the origin is infected at t=0. To prove the above main result, we show that the following phase transition occurs. Assuming that lceil log drceil vertices are infected at t=0, where these vertices can be located anywhere, then when the infection rate λ >λ _c, the process survives with high probability as d→ +∞ while when λ <λ _c, the process dies out at time O(log d) with high probability.

  17. Scaling-up Process-Oriented Guided Inquiry Learning Techniques for Teaching Large Information Systems Courses

    ERIC Educational Resources Information Center

    Trevathan, Jarrod; Myers, Trina; Gray, Heather

    2014-01-01

    Promoting engagement during lectures becomes significantly more challenging as class sizes increase. Therefore, lecturers need to experiment with new teaching methodologies to embolden deep learning outcomes and to develop interpersonal skills amongst students. Process Oriented Guided Inquiry Learning is a teaching approach that uses highly…

  18. Index Compression and Efficient Query Processing in Large Web Search Engines

    ERIC Educational Resources Information Center

    Ding, Shuai

    2013-01-01

    The inverted index is the main data structure used by all the major search engines. Search engines build an inverted index on their collection to speed up query processing. As the size of the web grows, the length of the inverted list structures, which can easily grow to hundreds of MBs or even GBs for common terms (roughly linear in the size of…

  19. Sublimites: An Uncommon Terrestrial Process with Large Implications for Planetary Sulfates

    NASA Astrophysics Data System (ADS)

    Massé, M.; Rondeau, B.; Thomas, M.; Ginot, P.; Bourgeois, O.; Schmitt, B.; De Angelis, M.; Civet, F.

    2016-09-01

    The analysis of a cold and dry glacier in the Chilean Andes reveals that sulfate crystals can form by sublimation only. This crystallization process may be dominant in the solar system and is particularly relevant for the martian North Polar Cap.

  20. Automated spray coating process for the fabrication of large-area artificial opals on textured substrates.

    PubMed

    Sprafke, Alexander N; Schneevoigt, Daniela; Seidel, Sophie; Schweizer, Stefan L; Wehrspohn, Ralf B

    2013-05-06

    3D photonic crystals, such as opals, have been shown to have a high potential to increase the efficiency of solar cells by enabling advanced light management concepts. However, methods which comply with the demands of the photovoltaic industry for integration of these structures, i. e. the fabrication in a low-cost, fast, and large-scale manner, are missing up to now. In this work, we present the spray coating of a colloidal suspension on textured substrates and subsequent drying. We fabricated opaline films of much larger lateral dimensions and in much shorter times than what is possible using conventional opal fabrication methods.

  1. Oceanographic Processes in Chilean Fjords of Patagonia: From small to large-scale studies

    NASA Astrophysics Data System (ADS)

    Iriarte, José L.; Pantoja, Silvio; Daneri, Giovanni

    2014-12-01

    Subantarctic ecosystems, such as the inner shelf of southern Chile (41-55°S), are characterized by a complex system of fjords, channels, gulf, estuaries, bays, and are affected by physical regimes that may strongly modulate biological productivity. Rhythms and rates of primary production in these highly fluctuating fjord environments depend to a large extent on the timing and magnitude of nutrient supply and light availability for primary producers. In such complex fjord systems, the interaction between oceanic waters and freshwater from multiple sources (e.g., rivers, surface and groundwater runoff, snow/glacier melting, and precipitation) produces strong vertical and horizontal gradients in salinity, density, organic and inorganic nutrient ratios and light availability (Pickard, 1971; Dávila et al., 2002; Silva and Palma 2006; Jacob et al., 2014). The vertical structure of the water column (stratified/mixed), modulated by the seasonal and inter-annual changes of the pycnocline may affect biomass and composition of pelagic and benthic assemblages, and ultimately spatial and temporal patterns of carbon fluxes (the 'Biological Pump'), and biogeochemical balances in this large region. In addition, the region is particularly vulnerable to climate change and anthropogenic influences (Iriarte et al., 2010). Remote and large-scale climatic-oceanographic phenomena (e.g., ENSO and Southern Annular Mode) and global climate trends may alter freshwater discharge of large rivers such as the Puelo and Palena, as has also been suggested for the Baker River located between Patagonian Ice fields and other northern fjords shown by paleo-oceanographic (Sepúlveda et al., 2009; Rebolledo et al., 2011) and dendrochronological studies (Lara et al., 2008). Although changes in climate are expected to alter the regional atmospheric forcing such as the West Wind Drift (Quintana and Aceituno, 2012; Garreaud et al., 2013) and the local ocean circulation in this region, including the

  2. ALIS (Auroral Large Imaging System) used for optical observations of the meteor impact process

    NASA Astrophysics Data System (ADS)

    Brändström, U.; Gustavsson, B.; Steen, A.; Pellinen-Wannberg, Asta

    2001-11-01

    This paper outlines a possibly new use of the Auroral Large Imaging System (ALIS) for studies of differential ablation phenomena in meteor trails. By simultaneous imaging from up to six stations, the altitude distribution of the meteor trails could be triangulated, while some stations simultaneously image the trails in for example the sodium (5893 Å) and calcium (4227 Å) lines. ALIS was primarily designed for auroral studies, but has also been used for studies of heater-induced airglow, polar stratospheric clouds as well as other phenomena. The system consits of six unmanned remote-controlled observation stations located in northern Sweden.

  3. Computer processing of large datasets in the diagnosis of cancer micrometastases in the bone marrow

    NASA Astrophysics Data System (ADS)

    Burov, D. A.; Selchuk, V. Y.; Beznos, O. A.; Obarevich, E. S.; Tupitsyn, N. N.

    2017-01-01

    To detect disseminated tumor cells (DTC) in the bone marrow in patients with solid tumors by flow cytometry it is necessary to analyze a very large number of cells (up to 100 million myelokaryocytes). We have proposed the use of a new generation flow cytometers with acoustic focusing, making it possible to analyze up to 20 mln events in one file. To improve the accuracy of our analysis we used fluorochromes with non-overlapping emission spectra, which makes it possible to minimize the need of setting compensation of cytometer. Identification of the target cell population detected by sequential logic gating.

  4. Research on precision grinding processing and compensation finishing experiment for mid-large- aperture square aspheric optical element

    NASA Astrophysics Data System (ADS)

    Nie, Fengming; Li, Zhanguo; Wang, Dasen; Zhang, Guangping; Guo, Chengjun; Pei, Ning; Li, Yupeng

    2014-08-01

    This paper analyzes dot-line envelope grinding principle, which is applicable to mid-large- aperture square aspheric optical element, determines the mathematical process control model based on X/Y/C three-axis aspheric grinding machine, We develop the appropriate high-precision aspheric grinding manufacturing and measurement systems software, using the plane grinding wheel to do the grinding experiments and the repeated compensation processing experiment. The experiments show that: high-precision aspheric grinding manufacturing and measurement systems software can be realized axisymmetric aspheric high-precision machining control and measurement; using compensation processing of the X/Y/C three-axis aspheric grinding machine which can effectively improve the precision PV value, surface error from the initial processing of the PV value :12 μm to the compensation processing of the PV value :3 μm .

  5. Post-processing of lattice dynamical data for large crystalline systems (disordered semiconductors)

    NASA Astrophysics Data System (ADS)

    Postnikov, Andrei

    2013-02-01

    In first-principes simulations of mixed semiconductors, the calculations ought to be done on large supercells, deprived of any symmetry due to random placement of atoms and their subsequent relaxation, even if underlying crystal structure is well defined. Calculation of force constants and subsequent diagonalization of the dynamical matrix produces large bulks of data in the form of very dense eigenvectors and long phonon eigenvectors. Different algorithms of projection help to extract meaningful information from these data, according to actual needs. Projections along with a given q-vector permit either (i) to enhance the genuinely zone-center phonon features, likely to be revealed in Raman or infrared spectra, or (ii) to reveal the traces of phonon dispersion as function of the q variation, in the situation where formally the translation symmetry is broken. Projections along with symmetry coordinates corresponding to different irreducible representations of the space group of the underlying perfect crystal help to approximatively attribute specific vibration patterns according to their symmetry properties, and hence to figure out experimental setup in which they can be observed. Similar techniques can be applied to the study of perfect crystals with complex structure, typically superlattices constructed from much simpler prototypes. The examples will be given from II-VI and III-V mixed (pseudobinary) semiconductors, from ternary and quaternary semiconductors used for photovoltaic applications, and others.

  6. Simulation of wastewater treatment by aerobic granules in a sequencing batch reactor based on cellular automata.

    PubMed

    Benzhai, Hai; Lei, Liu; Ge, Qin; Yuwan, Peng; Ping, Li; Qingxiang, Yang; Hailei, Wang

    2014-10-01

    In the present paper, aerobic granules were developed in a sequencing batch reactor (SBR) using synthetic wastewater, and 81 % of granular rate was obtained after 15-day cultivation. Aerobic granules have a 96 % BOD removal to the wastewater, and the reactor harbors a mount of biomass including bacteria, fungi and protozoa. In view of the complexity of kinetic behaviors of sludge and biological mechanisms of the granular SBR, a cellular automata model was established to simulate the process of wastewater treatment. The results indicate that the model not only visualized the complex adsorption and degradation process of aerobic granules, but also well described the BOD removal of wastewater and microbial growth in the reactor. Thus, CA model is suitable for simulation of synthetic wastewater treatment. This is the first report about dynamical and visual simulation of treatment process of synthetic wastewater in a granular SBR.

  7. Investigation of rifting processes in the Rio Grande Rift using data from unusually large earthquake swarms

    SciTech Connect

    Sanford, A.; Balch, R.; House, L.; Hartse, H.

    1995-12-01

    San Acacia Swarm in the Rio Grande Rift. Because the Rio Grande rift is one of the best seismically instrumented rift zones in the world, studying its seismicity provides an exceptional opportunity to explore the active tectonic processes within continental rifts. We have been studying earthquake swarms recorded near Socorro in an effort to link seismicity directly to the rifting process. For FY94, our research has focused on the San Acacia swarm, which occurred 25 km north of Socorro, New Mexico, along the accommodation zone between the Albuquerque-Belen and Socorro basins of the central Rio Grande rift. The swarm commenced on 25 February 1983, had a magnitude 4.2 main shock on 2 March and ended on 17 March, 1983.

  8. The TRIPSE: a process-oriented exam for large undergraduate classes.

    PubMed

    Nastos, Stash; Rangachari, P K

    2013-01-01

    The TRIPSE (tri-partite problem solving exercise), a process-oriented exam that mimics the scientific process, was used previously in small classes (15-25). Provided limited data, students frame explanations and design experimental tests that they later revise with additional information. Our 6-year experience using it with larger numbers (155-204) in a freshman biology course, suggests that it could provide a means of assessing individual student performance. Students rated the learning value of this experience to be significantly higher than a standard MCQ on a 10-point scale (TRIPSEs 8.2, CI 8.1/8.4 vs. MCQs 4.9, CI 4.8/5.1, n = 712). Additionally, we tested one cohort (n = 146) with a group TRIPSE (groups of 6), and found that this variant also provided a valuable learning experience (8.0, CI 7.7/8.3).

  9. Evolutionary Techniques for Image Processing a Large Dataset of Early Drosophila Gene Expression

    NASA Astrophysics Data System (ADS)

    Spirov, Alexander; Holloway, David M.

    2003-12-01

    Understanding how genetic networks act in embryonic development requires a detailed and statistically significant dataset integrating diverse observational results. The fruit fly ( Drosophila melanogaster) is used as a model organism for studying developmental genetics. In recent years, several laboratories have systematically gathered confocal microscopy images of patterns of activity (expression) for genes governing early Drosophila development. Due to both the high variability between fruit fly embryos and diverse sources of observational errors, some new nontrivial procedures for processing and integrating the raw observations are required. Here we describe processing techniques based on genetic algorithms and discuss their efficacy in decreasing observational errors and illuminating the natural variability in gene expression patterns. The specific developmental problem studied is anteroposterior specification of the body plan.

  10. Large-scale analytical Fourier transform of photomask layouts using graphics processing units

    NASA Astrophysics Data System (ADS)

    Sakamoto, Julia A.

    2015-10-01

    Compensation of lens-heating effects during the exposure scan in an optical lithographic system requires knowledge of the heating profile in the pupil of the projection lens. A necessary component in the accurate estimation of this profile is the total integrated distribution of light, relying on the squared modulus of the Fourier transform (FT) of the photomask layout for individual process layers. Requiring a layout representation in pixelated image format, the most common approach is to compute the FT numerically via the fast Fourier transform (FFT). However, the file size for a standard 26- mm×33-mm mask with 5-nm pixels is an overwhelming 137 TB in single precision; the data importing process alone, prior to FFT computation, can render this method highly impractical. A more feasible solution is to handle layout data in a highly compact format with vertex locations of mask features (polygons), which correspond to elements in an integrated circuit, as well as pattern symmetries and repetitions (e.g., GDSII format). Provided the polygons can decompose into shapes for which analytical FT expressions are possible, the analytical approach dramatically reduces computation time and alleviates the burden of importing extensive mask data. Algorithms have been developed for importing and interpreting hierarchical layout data and computing the analytical FT on a graphics processing unit (GPU) for rapid parallel processing, not assuming incoherent imaging. Testing was performed on the active layer of a 392- μm×297-μm virtual chip test structure with 43 substructures distributed over six hierarchical levels. The factor of improvement in the analytical versus numerical approach for importing layout data, performing CPU-GPU memory transfers, and executing the FT on a single NVIDIA Tesla K20X GPU was 1.6×104, 4.9×103, and 3.8×103, respectively. Various ideas for algorithm enhancements will be discussed.

  11. Research on large aperture multi-angle multi-surface mirror process technology

    NASA Astrophysics Data System (ADS)

    Huang, Ying; He, Manze; Yan, Dingyao; Liu, Yibin

    2016-10-01

    Light weighted multi-angle multi-surface mirror is made of glass-ceramic, with the structural characteristic of multicavity thin wall, high precision of surface figure and angle between surfaces, has very different processing technology with traditional solid mirror. Based on the 460mm×434mm×80mm multi-angle multi-surface mirror, glass combination manufacture method and relevant interferometry of angle measurement was designed. The process technology was studied, then the consistency of angle between surfaces and the influence on multi-cavity thin wall deformation of lateral surface and material of polishing pad on the surface figure processing were controlled. The model between the variation of angle and load was established, from which the hysteresis of angle variation was analyzed, then the prototype workpiece was finished. The difficult problem on synchronically controlling the surface angles and surface figure of the mirror, which has high center of gravity and multi-cavity thin wall, was solved. The lateral surface figure was controlled below λ/6 (PV, λ=632.8nm), and the perpendicularity of lateral surfaces were controlled below 5''.

  12. Processing and characterization of edgeless radiation detectors for large area detection

    NASA Astrophysics Data System (ADS)

    Kalliopuska, J.; Wu, X.; Jakubek, J.; Eränen, S.; Virolainen, T.

    2013-12-01

    The edgeless or active edge silicon pixel detectors have been gaining a lot of interest due to improved silicon processing capabilities. At VTT, we have recently triggered a multi-project wafer process of edgeless silicon detectors. Totally 80 pieces of 150 mm wafers were processed to provide a given number of detector variations. Fabricated detector thicknesses were 100, 200, 300 and 500 μm. The polarities of the fabricated detectors on the given thicknesses were n-in-n, p-in-n, n-in-p and p-in-p. On the n-in-n and n-in-p wafers the pixel isolation was made either with a common p-stop grid or with a shallow p-spray doping. The wafer materials were high resistivity Float Zone and Magnetic Czochralski silicon with crystal orientation of <100>. In this paper, the electric properties on various types of detectors are presented. The results from spectroscopic measurement show a good energy resolution of the edge pixels, indicating an excellent charge collection near the edge pixels of the edgeless detector.

  13. Measuring the In-Process Figure, Final Prescription, and System Alignment of Large Optics and Segmented Mirrors Using Lidar Metrology

    NASA Technical Reports Server (NTRS)

    Ohl, Raymond; Slotwinski, Anthony; Eegholm, Bente; Saif, Babak

    2011-01-01

    The fabrication of large optics is traditionally a slow process, and fabrication capability is often limited by measurement capability. W hile techniques exist to measure mirror figure with nanometer precis ion, measurements of large-mirror prescription are typically limited to submillimeter accuracy. Using a lidar instrument enables one to measure the optical surface rough figure and prescription in virtuall y all phases of fabrication without moving the mirror from its polis hing setup. This technology improves the uncertainty of mirror presc ription measurement to the micron-regime.

  14. Aerobic treatability of waste effluent from the leather finishing industry. Master's thesis

    SciTech Connect

    Vinger, J.A.

    1993-12-01

    The Seton Company supplies finished leather products exclusively for the automotive industry. In the process of finishing leather, two types of wastewaters are generated. The majority of the wastewater is composed of water-based paint residuals while the remainder is composed of solvent-based coating residuals. Aerobic treatability studies were conducted using water-based and solvent-based waste recirculatory waters from the Seton Company's Saxton, Pennsylvania processing plant. The specific objective was to determine the potential for using aerobic biological processes to biodegrade the industry's wastes and determine the potential for joint treatment at the local publicly owned treatment works (POTW). This study was accomplished in two phases. Phase I was conducted during the Spring Semester 1993 and consisted of aerobic respirometer tests of the raw wastes and mass balance analysis. The results of Phase I were published in a report to the Seton Company as Environmental Resources Research Institute project number 92C.II40R-1. Phase II was conducted during the Summer Semester 1993 and consisted of bench-scale reactor tests and additional aerobic respirometer tests. The aerobic respirometer batch tests and bench-scale reactor tests were used to assess the treatability of solvent-based and water-based wastewaters and determine the degree of biodegradability of the wastewaters. Mass balance calculations were made using measured characteristics.

  15. Real-time target detection technology of large view-field infrared image based on multicore DSP parallel processing

    NASA Astrophysics Data System (ADS)

    Sun, Gang; Liu, Songlin; Wang, Weihua; Chen, Zengping

    2013-10-01

    In order to implement real-time detection of hedgehopping target in large view-field infrared (LVIR) image, the paper proposes a fast algorithm flow to extract the target region of interest (ROI). The ground building region was rejected quickly and target ROI was segmented roughly through the background classification. Then the background image containing target ROI was matched with previous frame based on a mean removal normalized product correlation (MRNPC) similarity measure function. Finally, the target motion area was extracted by inter-frame difference in time domain. According to the proposed algorithm flow, this paper designs the high-speed real-time signal processing hardware platform based on FPGA + DSP, and also presents a new parallel processing strategy that called function-level and task-level, which could parallel process LVIR image by multi-core and multi-task. Experimental results show that the algorithm can extract low altitude aero target with complex background in large view effectively, and the new design hardware platform could implement real time processing of the IR image with 50000x288 pixels per second in large view-field infrared search system (LVIRSS).

  16. Large-Scale Reactive Atomistic Simulation of Shock-induced Initiation Processes in Energetic Materials

    NASA Astrophysics Data System (ADS)

    Thompson, Aidan

    2013-06-01

    Initiation in energetic materials is fundamentally dependent on the interaction between a host of complex chemical and mechanical processes, occurring on scales ranging from intramolecular vibrations through molecular crystal plasticity up to hydrodynamic phenomena at the mesoscale. A variety of methods (e.g. quantum electronic structure methods (QM), non-reactive classical molecular dynamics (MD), mesoscopic continuum mechanics) exist to study processes occurring on each of these scales in isolation, but cannot describe how these processes interact with each other. In contrast, the ReaxFF reactive force field, implemented in the LAMMPS parallel MD code, allows us to routinely perform multimillion-atom reactive MD simulations of shock-induced initiation in a variety of energetic materials. This is done either by explicitly driving a shock-wave through the structure (NEMD) or by imposing thermodynamic constraints on the collective dynamics of the simulation cell e.g. using the Multiscale Shock Technique (MSST). These MD simulations allow us to directly observe how energy is transferred from the shockwave into other processes, including intramolecular vibrational modes, plastic deformation of the crystal, and hydrodynamic jetting at interfaces. These processes in turn cause thermal excitation of chemical bonds leading to initial chemical reactions, and ultimately to exothermic formation of product species. Results will be presented on the application of this approach to several important energetic materials, including pentaerythritol tetranitrate (PETN) and ammonium nitrate/fuel oil (ANFO). In both cases, we validate the ReaxFF parameterizations against QM and experimental data. For PETN, we observe initiation occurring via different chemical pathways, depending on the shock direction. For PETN containing spherical voids, we observe enhanced sensitivity due to jetting, void collapse, and hotspot formation, with sensitivity increasing with void size. For ANFO, we

  17. Aerobic Exercise Intervention, Cognitive Performance, and Brain Structure: Results from the Physical Influences on Brain in Aging (PHIBRA) Study

    PubMed Central

    Jonasson, Lars S.; Nyberg, Lars; Kramer, Arthur F.; Lundquist, Anders; Riklund, Katrine; Boraxbekk, Carl-Johan

    2017-01-01

    Studies have shown that aerobic exercise has the potential to improve cognition and reduce brain atrophy in older adults. However, the literature is equivocal with regards to the specificity or generality of these effects. To this end, we report results on cognitive function and brain structure from a 6-month training intervention with 60 sedentary adults (64–78 years) randomized to either aerobic training or stretching and toning control training. Cognitive functions were assessed with a neuropsychological test battery in which cognitive constructs were measured using several different tests. Freesurfer was used to estimate cortical thickness in frontal regions and hippocampus volume. Results showed that aerobic exercisers, compared to controls, exhibited a broad, rather than specific, improvement in cognition as indexed by a higher “Cognitive score,” a composite including episodic memory, processing speed, updating, and executive function tasks (p = 0.01). There were no group differences in cortical thickness, but additional analyses revealed that aerobic fitness at baseline was specifically related to larger thickness in dorsolateral prefrontal cortex (dlPFC), and hippocampus volume was positively associated with increased aerobic fitness over time. Moreover, “Cognitive score” was related to dlPFC thickness at baseline, but changes in “Cognitive score” and dlPFC thickness were associated over time in the aerobic group only. However, aerobic fitness did not predict dlPFC change, despite the improvement in “Cognitive score” in aerobic exercisers. Our interpretation of these observations is that potential exercise-induced changes in thickness are slow, and may be undetectable within 6-months, in contrast to change in hippocampus volume which in fact was predicted by the change in aerobic fitness. To conclude, our results add to a growing literature suggesting that aerobic exercise has a broad influence on cognitive functioning, which may aid in

  18. Aerobic Exercise Intervention, Cognitive Performance, and Brain Structure: Results from the Physical Influences on Brain in Aging (PHIBRA) Study.

    PubMed

    Jonasson, Lars S; Nyberg, Lars; Kramer, Arthur F; Lundquist, Anders; Riklund, Katrine; Boraxbekk, Carl-Johan

    2016-01-01

    Studies have shown that aerobic exercise has the potential to improve cognition and reduce brain atrophy in older adults. However, the literature is equivocal with regards to the specificity or generality of these effects. To this end, we report results on cognitive function and brain structure from a 6-month training intervention with 60 sedentary adults (64-78 years) randomized to either aerobic training or stretching and toning control training. Cognitive functions were assessed with a neuropsychological test battery in which cognitive constructs were measured using several different tests. Freesurfer was used to estimate cortical thickness in frontal regions and hippocampus volume. Results showed that aerobic exercisers, compared to controls, exhibited a broad, rather than specific, improvement in cognition as indexed by a higher "Cognitive score," a composite including episodic memory, processing speed, updating, and executive function tasks (p = 0.01). There were no group differences in cortical thickness, but additional analyses revealed that aerobic fitness at baseline was specifically related to larger thickness in dorsolateral prefrontal cortex (dlPFC), and hippocampus volume was positively associated with increased aerobic fitness over time. Moreover, "Cognitive score" was related to dlPFC thickness at baseline, but changes in "Cognitive score" and dlPFC thickness were associated over time in the aerobic group only. However, aerobic fitness did not predict dlPFC change, despite the improvement in "Cognitive score" in aerobic exercisers. Our interpretation of these observations is that potential exercise-induced changes in thickness are slow, and may be undetectable within 6-months, in contrast to change in hippocampus volume which in fact was predicted by the change in aerobic fitness. To conclude, our results add to a growing literature suggesting that aerobic exercise has a broad influence on cognitive functioning, which may aid in explaining why

  19. Key ingredients needed when building large data processing systems for scientists

    NASA Technical Reports Server (NTRS)

    Miller, K. C.

    2002-01-01

    Why is building a large science software system so painful? Weren't teams of software engineers supposed to make life easier for scientists? Does it sometimes feel as if it would be easier to write the million lines of code in Fortran 77 yourself? The cause of this dissatisfaction is that many of the needs of the science customer remain hidden in discussions with software engineers until after a system has already been built. In fact, many of the hidden needs of the science customer conflict with stated needs and are therefore very difficult to meet unless they are addressed from the outset in a system's architectural requirements. What's missing is the consideration of a small set of key software properties in initial agreements about the requirements, the design and the cost of the system.

  20. GraphReduce: Processing Large-Scale Graphs on Accelerator-Based Systems

    SciTech Connect

    Sengupta, Dipanjan; Song, Shuaiwen; Agarwal, Kapil; Schwan, Karsten

    2015-11-15

    Recent work on real-world graph analytics has sought to leverage the massive amount of parallelism offered by GPU devices, but challenges remain due to the inherent irregularity of graph algorithms and limitations in GPU-resident memory for storing large graphs. We present GraphReduce, a highly efficient and scalable GPU-based framework that operates on graphs that exceed the device’s internal memory capacity. GraphReduce adopts a combination of edge- and vertex-centric implementations of the Gather-Apply-Scatter programming model and operates on multiple asynchronous GPU streams to fully exploit the high degrees of parallelism in GPUs with efficient graph data movement between the host and device.

  1. Floating substrate process: Large-area silicon sheet task low-cost solar array project

    NASA Technical Reports Server (NTRS)

    Garfinkel, M.; Hall, R. N.

    1978-01-01

    Supercooling of silicon-tin alloy melts was studied. Values as high as 78 C at 1100 C and 39 C at 1200 C were observed, corresponding to supersaturation parameter values 0.025 and 0.053 at 1050 C and 1150 C, respectively. The interaction of tin with silane gas streams was investigated over the temperature range 1000 to 1200 C. Single-pass conversion efficiencies exceeding 30% were obtained. The growth habit of spontaneously-nucleated surface growth was determined to be consistent with dendritic and web growth from singly-twinned triangular nucleii. Surface growth of interlocking silicon crystals, thin enough to follow the surface of the liquid and with growth velocity as high as 5 mm/min, was obtained. Large area single-crystal growth along the melt surface was not achieved. Small single-crystal surface growth was obtained which did not propagate beyond a few millimeters.

  2. Constraining the rupture processes of the intermediate and large earthquakes using geophysical data

    NASA Astrophysics Data System (ADS)

    Ji, C.

    2009-12-01

    Detailed mapping of spatiotemporal slip distributions of large earthquakes is one of the principal goals of seismology. Since the finite-fault inversion method was first introduced during the studies of the 1979 Imperial Valley, California, earthquake, it becomes the sharpest tool in the study of earthquake seismology. Various new developments in terms of source representations, inverse methods, objective functions, have been conducted even since to improve its resolution and robustness. The geophysical datasets other than seismic data, such as GPS, Interferometric and geological surface offsets, are also been included to extend the data coverage spatially. With recent developments in global broadband seismic instrumentations, it has become possible to routinely study the earthquake slip history in realtime, and proceed to predict the local damage. In this poster, I will summarize the our recent developments in the procedure of the realtime finite fault inversions, in terms of data coverage, fault geometry, earth structures, and error analysis.

  3. Low-impedance internal linear inductive antenna for large-area flat panel display plasma processing

    SciTech Connect

    Kim, K.N.; Jung, S.J.; Lee, Y.J.; Yeom, G.Y.; Lee, S.H.; Lee, J.K.

    2005-03-15

    An internal-type linear inductive antenna, that is, a double-comb-type antenna, was developed for a large-area plasma source having the size of 1020 mmx830 mm, and high density plasmas on the order of 2.3x10{sup 11} cm{sup -3} were obtained with 15 mTorr Ar at 5000 W of inductive power with good plasma stability. This is higher than that for the conventional serpentine-type antenna, possibly due to the low impedance, resulting in high efficiency of power transfer for the double-comb antenna type. In addition, due to the remarkable reduction of the antenna length, a plasma uniformity of less than 8% was obtained within the substrate area of 880 mmx660 mm at 5000 W without having a standing-wave effect.

  4. Structures and Techniques For Implementing and Packaging Complex, Large Scale Microelectromechanical Systems Using Foundry Fabrication Processes.

    DTIC Science & Technology

    1996-06-01

    Figure 6-4. Compressive wiring connecting a die to a printed circuit board 6-12 Figure 6-5. Single glob-topped die mounted directly on a printed ...two minutes 6-54 Figure 6-31. MMS MCM test package before MEMS release etch processing 6-60 Figure 6-32. LCD watch printed circuit board rebuilt...95J-02, June 1995. 36 G. Fuhr, R. Hagedorn, T. Müller, W. Benecke and B. Wagner, "Microfabricated electrohydrodynamic (EHD) pumps for liquids of

  5. Low cost silicon solar array project large area silicon sheet task: Silicon web process development

    NASA Technical Reports Server (NTRS)

    Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Blais, P. D.; Davis, J. R., Jr.

    1977-01-01

    Growth configurations were developed which produced crystals having low residual stress levels. The properties of a 106 mm diameter round crucible were evaluated and it was found that this design had greatly enhanced temperature fluctuations arising from convection in the melt. Thermal modeling efforts were directed to developing finite element models of the 106 mm round crucible and an elongated susceptor/crucible configuration. Also, the thermal model for the heat loss modes from the dendritic web was examined for guidance in reducing the thermal stress in the web. An economic analysis was prepared to evaluate the silicon web process in relation to price goals.

  6. Investigation of the Physical Processes Governing Large-Scale Tracer Transport in the Stratosphere and Troposphere

    NASA Technical Reports Server (NTRS)

    Selkirk, Henry B.

    2001-01-01

    This report summarizes work conducted from January 1996 through April 1999 on a program of research to investigate the physical mechanisms that underlie the transport of trace constituents in the stratosphere-troposphere system. The primary scientific goal of the research has been to identify the processes which transport air masses within the lower stratosphere, particularly between the tropics and middle latitudes. This research was conducted in collaboration with the Subsonic Assessment (SASS) of the NASA Atmospheric Effects of Radiation Program (AEAP) and the Upper Atmospheric Research Program (UARP). The SASS program sought to understand the impact of the present and future fleets of conventional jet traffic on the upper troposphere and lower stratosphere, while complementary airborne observations under UARP seek to understand the complex interactions of dynamical and chemical processes that affect the ozone layer. The present investigation contributed to the goals of each of these by diagnosing the history of air parcels intercepted by NASA research aircraft in UARP and AEAP campaigns. This was done by means of a blend of trajectory analyses and tracer correlation techniques.

  7. Plasma Processing of Large Curved Nb Surfaces with Application to SRF Cavities

    NASA Astrophysics Data System (ADS)

    Upadhyay, Janardan; Im, Do; Miller, Frederick; Popovic, Svetozar; Vuskovic, Leposava; Phillips, Larry; Valente-Felliciano, Anne-Marie

    2013-09-01

    Surface modification of superconducting radio-frequency (SRF) cavities are a promising alternative to the wet etching technologies that are currently applied to Nb cavities. We have built a Nb etching cylindrical discharge chamber, comparable by volume to 1.5 GHz resonant cavity with 8 observation ports for holding the Nb samples, spectral observations, and electric probe measurements. Several asymmetric discharge configurations were tested with a variety of pressure, power and gas composition combinations. All discharges have been operated in Ar/Cl2 gas mixtures with Cl2 content up to 15%. Plasma parameters were evaluated using a Langmuir probe, and an optical emission spectroscopy based on the relative intensities of two specific Ar 5p-4s lines at 419.83 and 420.07 nm, respectively. We have also carried out a systematic study of atomic and molecular spectra during Nb etching in order to determine the most appropriate process signature. The effects of discharge conditions and parameters are intended to be used as guidelines for optimal design of SRF cavity etching processes. Supported by DOE under grant no. DE-SC0007879. JU acknowledges support by JSA/DOE via DE-AC05-06OR23177.

  8. Large deviations in stochastic heat-conduction processes provide a gradient-flow structure for heat conduction

    SciTech Connect

    Peletier, Mark A.; Redig, Frank; Vafayi, Kiamars

    2014-09-01

    We consider three one-dimensional continuous-time Markov processes on a lattice, each of which models the conduction of heat: the family of Brownian Energy Processes with parameter m (BEP(m)), a Generalized Brownian Energy Process, and the Kipnis-Marchioro-Presutti (KMP) process. The hydrodynamic limit of each of these three processes is a parabolic equation, the linear heat equation in the case of the BEP(m) and the KMP, and a nonlinear heat equation for the Generalized Brownian Energy Process with parameter a (GBEP(a)). We prove the hydrodynamic limit rigorously for the BEP(m), and give a formal derivation for the GBEP(a). We then formally derive the pathwise large-deviation rate functional for the empirical measure of the three processes. These rate functionals imply gradient-flow structures for the limiting linear and nonlinear heat equations. We contrast these gradient-flow structures with those for processes describing the diffusion of mass, most importantly the class of Wasserstein gradient-flow systems. The linear and nonlinear heat-equation gradient-flow structures are each driven by entropy terms of the form -log ρ; they involve dissipation or mobility terms of order ρ² for the linear heat equation, and a nonlinear function of ρ for the nonlinear heat equation.

  9. Long-term aerobic exercise is associated with greater muscle strength throughout the life span.

    PubMed

    Crane, Justin D; Macneil, Lauren G; Tarnopolsky, Mark A

    2013-06-01

    Aging is associated with a progressive decline in muscle strength, muscle mass, and aerobic capacity, which reduces mobility and impairs quality of life in elderly adults. Exercise is commonly employed to improve muscle function in individuals of all ages; however, chronic aerobic exercise is believed to largely impact cardiovascular function and oxidative metabolism, with minimal effects on muscle mass and strength. To study the effects of long-term aerobic exercise on muscle strength, we recruited 74 sedentary (SED) or highly aerobically active (ACT) men and women from within three distinct age groups (young: 20-39 years, middle: 40-64 years, and older: 65-86 years) and tested their aerobic capacity, isometric grip and knee extensor strength, and dynamic 1 repetition maximum knee extension. As expected, ACT subjects had greater maximal oxygen uptake and peak aerobic power output compared with SED subjects (p < .05). Grip strength relative to body weight declined with age (p < .05) and was greater in ACT compared with SED subjects in both hands (p < .05). Similarly, relative maximal isometric knee extension torque declined with age (p < .05) and was higher in ACT versus SED individuals in both legs (p < .05). Absolute and relative 1 repetition maximum knee extension declined with age (p < .05) and were greater in ACT versus SED groups (p < .05). Knee extensor strength was associated with a greater amount of leg lean mass in the ACT subjects (p < .05). In summary, long-term aerobic exercise appears to attenuate age-related reductions in muscle strength in addition to its cardiorespiratory and metabolic benefits.

  10. Biological wastewater treatment by a bioreactor with repeated coupling of aerobes and anaerobes aiming at on-site reduction of excess sludge.

    PubMed

    Yu, Anfeng; Feng, Quan; Liu, Zehua; Zhou, Yunan; Xing, Xin-Hui

    2006-01-01

    Activated sludge has been widely used in wastewater treatment throughout the world. However, the biggest disadvantage of this method is the by-production of excess sludge in a large amount, resulting in difficulties in operation and high costs for wastewater treatment. Technological innovations for wastewater treatment capable of reducing excess sludge have thus become research topics of interest in recent years. In our present research, we developed a new biological wastewater treatment process by repeated coupling of aerobes and anaerobes (rCAA) to reduce the excess sludge during the treatment of wastewater. During 460-day continuous running, COD (300-700 mg/L) and TOC (100-350 mg/L) were effectively removed, of which the removal rate was above 80 and 90%, respectively. SS in the effluent was 13 mg/L on average in the rCAA bioreactor without a settling tank. The on-site reduction of the excess sludge in the rCAA might be contributed by several mechanisms. The degradation of the grown aerobes after moving into the anaerobic regions was considered to be one of the most important factors. Besides, the repeatedly coupling of aerobes and anaerobes could also result in a complex microbial community with more metazoans and decoupling of the microbial anabolism and catabolism.

  11. A vacuum flash-assisted solution process for high-efficiency large-area perovskite solar cells

    NASA Astrophysics Data System (ADS)

    Li, Xiong; Bi, Dongqin; Yi, Chenyi; Décoppet, Jean-David; Luo, Jingshan; Zakeeruddin, Shaik Mohammed; Hagfeldt, Anders; Grätzel, Michael

    2016-07-01

    Metal halide perovskite solar cells (PSCs) currently attract enormous research interest because of their high solar-to-electric power conversion efficiency (PCE) and low fabrication costs, but their practical development is hampered by difficulties in achieving high performance with large-size devices. We devised a simple vacuum flash-assisted solution processing method to obtain shiny, smooth, crystalline perovskite films of high electronic quality over large areas. This enabled us to fabricate solar cells with an aperture area exceeding 1 square centimeter, a maximum efficiency of 20.5%, and a certified PCE of 19.6%. By contrast, the best certified PCE to date is 15.6% for PSCs of similar size. We demonstrate that the reproducibility of the method is excellent and that the cells show virtually no hysteresis. Our approach enables the realization of highly efficient large-area PSCs for practical deployment.

  12. Negative ion production and beam extraction processes in a large ion source (invited)

    SciTech Connect

    Tsumori, K. Nakano, H.; Goto, M.; Nagaoka, K.; Osakabe, M.; Takeiri, Y.; Kaneko, O.; Ikeda, K.; Kisaki, M.; Geng, S.; Wada, M.; Sasaki, K.; Nishiyama, S.; Serianni, G.; Agostinetti, P.; Sartori, E.; Brombin, M.; Veltri, P.; Wimmer, C.

    2016-02-15

    Recent research results on negative-ion-rich plasmas in a large negative ion source have been reviewed. Spatial density and flow distributions of negative hydrogen ions (H{sup −}) and positive hydrogen ions together with those of electrons are investigated with a 4-pin probe and a photodetachment (PD) signal of a Langmuir probe. The PD signal is converted to local H{sup −} density from signal calibration to a scanning cavity ring down PD measurement. Introduction of Cs changes the slope of plasma potential local distribution depending upon the plasma grid bias. A higher electron density H{sub 2} plasma locally shields the bias potential and behaves like a metallic free electron gas. On the other hand, the bias and extraction electric fields penetrate in a Cs-seeded electronegative plasma even when the electron density is similar. Electrons are transported by the penetrated electric fields from the driver region along and across the filter and electron deflection magnetic fields. Plasma ions exhibited a completely different response against the penetration of electric fields.

  13. Manufacturable MBE growth process for Sb-based photodetector materials on large diameter substrates

    NASA Astrophysics Data System (ADS)

    Lubyshev, Dmitri; Qiu, Yueming; Fastenau, Joel M.; Liu, Amy W. K.; Koerperick, Edwin J.; Olesberg, Jon T.; Norton, Dennis, Jr.

    2012-01-01

    Antimony-based photodetector materials have attracted considerable interest for their potential and demonstrated performance in infrared detection and imaging applications. Mid-wavelength infrared detector has been demonstrated using bulk InAsSb/AlAsSb-based nBn structures. Heterostructures based on InAs/Ga(In)Sb strained layer superlattices create a type-II band alignment that can be tailored to cover a wide range of the mid- and long-wavelength infrared absorption bands by varying the thickness and composition of the constituent materials. Through careful design, these Sb-based detectors can realize desirable features such as higher operating temperature, better uniformity, suppression of Auger recombination, reduction of tunneling currents, and higher quantum efficiency. The manufacturing challenge of these structures is the reproducible growth of high-quality Sb-based epiwafers due to their complex designs including large numbers of alternating thin layers and mixed group-V elements. In this paper, we discuss the manufacturability of such epiwafers on 3" and 4" diameter GaSb substrates by molecular beam epitaxy using multi-wafer production tools. Various techniques were used to characterize the material properties of these wafers, including high-resolution x-ray diffraction, low-temperature photoluminescence, Nomarski optical microscopy, and atomic force microscopy.

  14. On uniform plasma generation for the large area plasma processing in intermediate pressures

    SciTech Connect

    Kim, Hyun Jun; Hwang, Hye-Ju; Cho, Jeong Hee; Chae, Hee Sun; Kim, Dong Hwan; Chung, Chin-Wook

    2015-04-21

    Radial plasma discharge characteristics in the range of 450 mm were studied in a dual inductively coupled plasma (ICP) source, which consisted of a helical ICP and the side type ferrite ICPs. Since the energy relaxation length is shorter than the distance between each of the ferrite ICPs in an intermediate pressure (600 mTorr), local difference in the plasma ignition along the antenna position were observed. In addition, large voltage drop in the discharge of the ferrite ICPs causes an increase in the displacement current to the plasma, and separate discharge mode (E and H mode) according to the antenna position was observed. This results in non-uniform plasma distribution. For the improvement in the discharge of the ferrite ICPs, a capacitor which is placed between the ends of antenna and the ground is adjusted to minimize the displacement current to the plasma. As a result, coincident transitions from E to H mode were observed along the antenna position, and radially concave density profile (edge focused) was measured. For the uniform density distribution, a helical ICP, which located at the center of the discharge chamber, was simultaneously discharged with the ferrite ICPs. Due to the plasma potential variation through the simultaneous discharge of helical ICP and ferrite ICPs, uniform radial distribution in both plasma density and electron temperature are achieved.

  15. Ocean acidification induces biochemical and morphological changes in the calcification process of large benthic foraminifera

    PubMed Central

    Prazeres, Martina; Uthicke, Sven; Pandolfi, John M.

    2015-01-01

    Large benthic foraminifera are significant contributors to sediment formation on coral reefs, yet they are vulnerable to ocean acidification. Here, we assessed the biochemical and morphological impacts of acidification on the calcification of Amphistegina lessonii and Marginopora vertebralis exposed to different pH conditions. We measured growth rates (surface area and buoyant weight) and Ca-ATPase and Mg-ATPase activities and calculated shell density using micro-computer tomography images. In A. lessonii, we detected a significant decrease in buoyant weight, a reduction in the density of inner skeletal chambers, and an increase of Ca-ATPase and Mg-ATPase activities at pH 7.6 when compared with ambient conditions of pH 8.1. By contrast, M. vertebralis showed an inhibition in Mg-ATPase activity under lowered pH, with growth rate and skeletal density remaining constant. While M. vertebralis is considered to be more sensitive than A. lessonii owing to its high-Mg-calcite skeleton, it appears to be less affected by changes in pH, based on the parameters assessed in this study. We suggest difference in biochemical pathways of calcification as the main factor influencing response to changes in pH levels, and that A. lessonii and M. vertebralis have the ability to regulate biochemical functions to cope with short-term increases in acidity. PMID:25694619

  16. Process effects on activated carbon with large specific surface area from corn cob.

    PubMed

    Cao, Qing; Xie, Ke-Chang; Lv, Yong-Kang; Bao, Wei-Ren

    2006-01-01

    The main factors that affect the large specific surface area (SSA) of the activated carbon from agricultural waste corn cobs were studied by chemically activated method with solution of KOH and soap which acted as surfactant. The experiment showed that not only the activation temperature, activation time and the mass ratio of KOH to the carbonized material, but also the activated methods using activator obviously influenced the SSA of activated carbon. The experimental operating conditions were as follows: the carbonized temperature being 450 degrees C and keeping time being 4 h using N2 as protective gas; the activation temperature being 850 degrees C and holding time being 1.2 h; the mass ratio of KOH to carbonized material being 4.0; the time of soaking carbonized material in the solution of KOH and soap being 30 min. Under the optimal conditions, the SSA of activated carbon from corn cobs reached 2700 m2/g. And the addition of the soap as surfactant may shorten the soaking time. The structure of the activated carbon prepared had narrow distribution of pore size and the micro-pores accounted for 78%. The advantages of the method described were easy and feasible.

  17. Therapeutic aspects of aerobic dance participation.

    PubMed

    Estivill, M

    1995-01-01

    An ethnographic analysis of aerobic dance exercise culture was conducted to determine the impact of the culture on the mind-body connection. After a review of the predominant theories on the relationship between vigorous exercise and elevated mood, aerobic dance participants' experiences are reported to illustrate how cognitive experience and self-esteem may be influenced. Interviews revealed that some participants achieved a pleasantly altered state of consciousness and respite from depression and stress. The relationship of the work ethic to achievement of participant satisfaction is underscored.

  18. On the possibility of the multiple inductively coupled plasma and helicon plasma sources for large-area processes

    SciTech Connect

    Lee, Jin-Won; Lee, Yun-Seong Chang, Hong-Young; An, Sang-Hyuk

    2014-08-15

    In this study, we attempted to determine the possibility of multiple inductively coupled plasma (ICP) and helicon plasma sources for large-area processes. Experiments were performed with the one and two coils to measure plasma and electrical parameters, and a circuit simulation was performed to measure the current at each coil in the 2-coil experiment. Based on the result, we could determine the possibility of multiple ICP sources due to a direct change of impedance due to current and saturation of impedance due to the skin-depth effect. However, a helicon plasma source is difficult to adapt to the multiple sources due to the consistent change of real impedance due to mode transition and the low uniformity of the B-field confinement. As a result, it is expected that ICP can be adapted to multiple sources for large-area processes.

  19. Design of an RF Antenna for a Large0Bore, High Power, Steady State Plasma Processing Chamber for Material Separation

    SciTech Connect

    Rasmussen, D.A.; Freeman, R.L.

    2001-11-07

    The purpose of this Cooperative Research and Development Agreement (CRADA) between UT-Battelle, LLC, (Contractor), and Archimedes Technology Group, (Participant) is to evaluate the design of an RF antenna for a large-bore, high power, steady state plasma processing chamber for material separation. Criteria for optimization will be to maximize the power deposition in the plasma while operating at acceptable voltages and currents in the antenna structure. The project objectives are to evaluate the design of an RF antenna for a large-bore, high power, steady state plasma processing chamber for material separation. Criteria for optimization will be to maximize the power deposition in the plasma while operating at acceptable voltages and currents in the antenna structure.

  20. Large-scale fabrication of In2S3 porous films via one-step hydrothermal process.

    PubMed

    Chen, Fei; Deng, Dan; Lei, Yinlin

    2013-10-01

    Large-scale indium sulfide (In2S3) porous films were fabricated via a facile one-step and non-template hydrothermal process using L-cysteine as a capping agent. The impact of reaction conditions such as reaction time, temperatures, and capping agents on the synthesis of the In2S3 porous films were studied. The morphology, structure, and phase composition of In2S3 porous films were characterized by X-ray diffraction (XRD), field-emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM). The formation process and the optical property of the In2S3 porous films were also evaluated.

  1. In-situ monitoring of surface post-processing in large aperture fused silica optics with Optical Coherence Tomography

    SciTech Connect

    Guss, G M; Bass, I l; Hackel, R P; Mailhiot, C; Demos, S G

    2008-02-08

    Optical Coherence Tomography is explored as a method to image laser-damage sites located on the surface of large aperture fused silica optics during post-processing via CO{sub 2} laser ablation. The signal analysis for image acquisition was adapted to meet the sensitivity requirements for this application. A long-working distance geometry was employed to allow imaging through the opposite surface of the 5-cm thick optic. The experimental results demonstrate the potential of OCT for remote monitoring of transparent material processing applications.

  2. Preparation of large-particle-size monodisperse latexes in space - Polymerization kinetics and process development

    NASA Technical Reports Server (NTRS)

    Vanderhoff, J. W.; El-Aasser, M. S.; Micale, F. J.; Sudol, E. D.; Tseng, C. M.; Silwanowicz, A.; Kornfeld, D. M.

    1984-01-01

    Monodisperse polystyrene latexes are prepared by seeded emulsion polymerization; however, sizes larger than 2 microns are difficult to prepare because of the creaming and settling of the particles and their sensitivity to mechanical shear. Preparation in space would obviate the creaming and settling, and allow agitation just sufficient for good heat transfer and mixing. Three polymerizations yielding 3-5 micron size particles were carried out successfully on the third flight of the 'Columbia' launched Mar. 22, 1982; however, four polymerizations yielding sizes up to 10 microns on the fourth flight launched June 27, 1982 were incomplete owing to apparatus malfunction. The results of these polymerizations and the prospects of developing a preparative space process are reviewed.

  3. Large and small scale ethyl alcohol manufacturing processes from agricultural raw materials

    SciTech Connect

    Paul, J.K.

    1980-01-01

    This volume provides the reader with process descriptions and economic evaluations for ethyl alcohol manufacturing plants with capacities ranging from 25 gallons per hour to 100 million gallons per year. Most fully described are the 50 million gallon per year and 25 gallon per hour facilities. The book is divided into four parts. Each part details a specific sized system from a particular starting material, with possible excursions on additional sized systems. Part 1: Alcohol manufacture from corn on a 50 million gallon per year scale, with excursions to 10 and 100 million gallons per year. Part 2: Wheat straw conversion via enzymatic hydrolysis for a 25 million gallon per year facility. Part 3: Molasses fermentation to produce 14 million gallons per year. Part 4: A guide to small scale (25 gallons per hour) production. Also included are discussions of legislation and permit information pertinent to alcohol plant operation, environmental considerations, plus lists of resource people and organizations involved in alcohol promotion.

  4. The Montage architecture for grid-enabled science processing of large, distributed datasets

    NASA Technical Reports Server (NTRS)

    Jacob, Joseph C.; Katz, Daniel S .; Prince, Thomas; Berriman, Bruce G.; Good, John C.; Laity, Anastasia C.; Deelman, Ewa; Singh, Gurmeet; Su, Mei-Hui

    2004-01-01

    Montage is an Earth Science Technology Office (ESTO) Computational Technologies (CT) Round III Grand Challenge investigation to deploy a portable, compute-intensive, custom astronomical image mosaicking service for the National Virtual Observatory (NVO). Although Montage is developing a compute- and data-intensive service for the astronomy community, we are also helping to address a problem that spans both Earth and Space science, namely how to efficiently access and process multi-terabyte, distributed datasets. In both communities, the datasets are massive, and are stored in distributed archives that are, in most cases, remote from the available Computational resources. Therefore, state of the art computational grid technologies are a key element of the Montage portal architecture. This paper describes the aspects of the Montage design that are applicable to both the Earth and Space science communities.

  5. Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries.

    PubMed

    Seals, Douglas R

    2014-09-01

    Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in modern societies, and advancing age is the major risk factor for CVD. Arterial dysfunction, characterized by large elastic artery stiffening and endothelial dysfunction, is the key event leading to age-associated CVD. Our work shows that regular aerobic exercise inhibits large elastic artery stiffening with aging (optimizes arterial compliance) and preserves endothelial function. Importantly, among previously sedentary late middle-aged and older adults, aerobic exercise improves arterial stiffness and enhances endothelial function in most groups and, therefore, also can be considered a treatment for age-associated arterial dysfunction. The mechanisms by which regular aerobic exercise destiffens large elastic arteries are incompletely understood, but existing evidence suggests that reductions in oxidative stress associated with decreases in both adventitial collagen (fibrosis) and advanced glycation end-products (structural protein cross-linking molecules), play a key role. Aerobic exercise preserves endothelial function with aging by maintaining nitric oxide bioavailability via suppression of excessive superoxide-associated oxidative stress, and by inhibiting the development of chronic low-grade vascular inflammation. Recent work from our laboratory supports the novel hypothesis that aerobic exercise may exert these beneficial effects by directly inducing protection to aging arteries against multiple adverse factors to which they are chronically exposed. Regular aerobic exercise should be viewed as a "first line" strategy for prevention and treatment of arterial aging and a vital component of a contemporary public health approach for reducing the projected increase in population CVD burden.

  6. Activation of large form galanin-LI by extracellular processing in small cell lung carcinoma tissue.

    PubMed

    Yamamoto, Hiroyuki; Iguchi, Kazuaki; Ohno, Satoshi; Yokogawa, Takashi; Nishikawa, Kazuya; Hoshino, Minoru

    2011-10-01

    Galanin is a neuropeptide that is widely distributed in the central and peripheral nervous systems. Some small cell lung carcinoma (SCLC) cell lines such as SBC-3A release only the high-molecular-mass form, with lower molecular mass forms being undetectable. To investigate the mechanism of processing of progalanin to active peptide, we studied galanin-LI in both the culture media of SBC-3A cells and in extracts from in vivo mouse SBC-3A tumors. SBC-3A cells were found to release high molecular mass galanin, but did not release active peptides. In contrast, tumor extract contained both high-molecular-mass galanin, and a cleaved lower-molecular-mass form of the peptide (8, 5 and 2 kDa). The lower-molecular-mass peptide was identified as galanin(1-20) by MALDI-TOF mass spectrometry. We then looked at MMP-2 and MMP-9 release from SBC-3A cells and tumor tissue treated with galanin and progalanin, as revealed by gelatin zymography. Galanin elicited pro-MMP-2 and pro-MMP-9 release from SBC-3A cells and tumor tissue; however, recombinant progalanin induced pro-MMP-2 and pro-MMP-9 release from tumor tissue only. This study has shown that the galanin-LI released from SCLC SBC-3A cells consisted of the high-molecular-mass peptide form, and was processed extracellularly to galanin(1-20). Furthermore, galanin was seen to induce pro-MMP-2 and pro-MMP-9 release from SBC-3A cells.

  7. AsterAnts: A Concept for Large-Scale Meteoroid Return and Processing using the International Space Station

    NASA Technical Reports Server (NTRS)

    Globus, Al; Biegel, Bryan A.; Traugott, Steve

    2004-01-01

    AsterAnts is a concept calling for a fleet of solar sail powered spacecraft to retrieve large numbers of small (1/2-1 meter diameter) Near Earth Objects (NEOs) for orbital processing. AsterAnts could use the International Space Station (ISS) for NEO processing, solar sail construction, and to test NEO capture hardware. Solar sails constructed on orbit are expected to have substantially better performance than their ground built counterparts [Wright 1992]. Furthermore, solar sails may be used to hold geosynchronous communication satellites out-of-plane [Forward 1981] increasing the total number of slots by at least a factor of three. potentially generating $2 billion worth of orbital real estate over North America alone. NEOs are believed to contain large quantities of water, carbon, other life-support materials and metals. Thus. with proper processing, NEO materials could in principle be used to resupply the ISS, produce rocket propellant, manufacture tools, and build additional ISS working space. Unlike proposals requiring massive facilities, such as lunar bases, before returning any extraterrestrial larger than a typical inter-planetary mission. Furthermore, AsterAnts could be scaled up to deliver large amounts of material by building many copies of the same spacecraft, thereby achieving manufacturing economies of scale. Because AsterAnts would capture NEOs whole, NEO composition details, which are generally poorly characterized, are relatively unimportant and no complex extraction equipment is necessary. In combination with a materials processing facility at the ISS, AsterAnts might inaugurate an era of large-scale orbital construction using extraterrestrial materials.

  8. Bursting process of large- and small-scale structures in turbulent boundary layer perturbed by a cylinder roughness element

    NASA Astrophysics Data System (ADS)

    Tang, Zhanqi; Jiang, Nan; Zheng, Xiaobo; Wu, Yanhua

    2016-05-01

    Hot-wire measurements on a turbulent boundary layer flow perturbed by a wall-mounted cylinder roughness element (CRE) are carried out in this study. The cylindrical element protrudes into the logarithmic layer, which is similar to those employed in turbulent boundary layers by Ryan et al. (AIAA J 49:2210-2220, 2011. doi: 10.2514/1.j051012) and Zheng and Longmire (J Fluid Mech 748:368-398, 2014. doi: 10.1017/jfm.2014.185) and in turbulent channel flow by Pathikonda and Christensen (AIAA J 53:1-10, 2014. doi: 10.2514/1.j053407). The similar effects on both the mean velocity and Reynolds stress are observed downstream of the CRE perturbation. The series of hot-wire data are decomposed into large- and small-scale fluctuations, and the characteristics of large- and small-scale bursting process are observed, by comparing the bursting duration, period and frequency between CRE-perturbed case and unperturbed case. It is indicated that the CRE perturbation performs the significant impact on the large- and small-scale structures, but within the different impact scenario. Moreover, the large-scale bursting process imposes a modulation on the bursting events of small-scale fluctuations and the overall trend of modulation is not essentially sensitive to the present CRE perturbation, even the modulation extent is modified. The conditionally averaging fluctuations are also plotted, which further confirms the robustness of the bursting modulation in the present experiments.

  9. The Large Impact Process Inferred from the Geology of Lunar Multiring Basins

    NASA Technical Reports Server (NTRS)

    Spudis, Paul D.

    1994-01-01

    The study of the geology of multiring impact basins on the Moon over the past ten years has given us a rudimentary understanding of how these large structures have formed and evolved on the Moon and other bodies. Two-ring basins on the Moon begin to form at diameters of about 300 km; the transition diameter at which more than two rings appear is uncertain, but it appears to be between 400 and 500 km in diameter. Inner rings tend to be made up of clusters or aligned segments of massifs and are arranged into a crudely concentric pattern; scarp-like elements may or may not be present. Outer rings are much more scarp-like and massifs are rare to absent. Basins display textured deposits, interpreted as ejecta, extending roughly an apparent basin radius exterior to the main topographic rim. Ejecta may have various morphologies, ranging from wormy and hummocky deposits to knobby surfaces; the causes of these variations are not known, but may be related to the energy regime in which the ejecta are deposited. Outside the limits of the textured ejecta are found both fields of satellitic craters (secondaries) and light plains deposits. Impact melt sheets are observed on the floors of relatively unflooded basins. Samples of impact melts from lunar basins have basaltic major-element chemistry, characterized by K, rare-earth elements (REE), P, and other trace elements of varying concentration (KREEP); ages are between 3.8 and 3.9 Ga. These lithologies cannot be produced through the fusion of known pristine (plutonic) rock types, suggesting the occurrence of unknown lithologies within the Moon. These melts were probably generated at middle to lower crustal levels. Ejecta compositions, preservation of pre-basin topography, and deposit morphologies all indicate that the excavation cavity of multiring basins is between about 0.4 and 0.6 times the diameter of the apparent crater diameter. Basin depths of excavation can be inferred from the composition of basin ejecta. A variety of

  10. Aerobic Exercise and Other Healthy Lifestyle Factors That Influence Vascular Aging

    ERIC Educational Resources Information Center

    Santos-Parker, Jessica R.; LaRocca, Thomas J.; Seals, Douglas R

    2014-01-01

    Cardiovascular diseases (CVDs) remain the leading cause of death in the United States and other modern societies. Advancing age is the major risk factor for CVD, primarily due to stiffening of the large elastic arteries and the development of vascular endothelial dysfunction. In contrast, regular aerobic exercise protects against the development…

  11. Resin Film Infusion (RFI) Process Modeling for Large Transport Aircraft Wing Structures

    NASA Technical Reports Server (NTRS)

    Loos, Alfred C.; Caba, Aaron C.; Furrow, Keith W.

    2000-01-01

    This investigation completed the verification of a three-dimensional resin transfer molding/resin film infusion (RTM/RFI) process simulation model. The model incorporates resin flow through an anisotropic carbon fiber preform, cure kinetics of the resin, and heat transfer within the preform/tool assembly. The computer model can predict the flow front location, resin pressure distribution, and thermal profiles in the modeled part. The formulation for the flow model is given using the finite element/control volume (FE/CV) technique based on Darcy's Law of creeping flow through a porous media. The FE/CV technique is a numerically efficient method for finding the flow front location and the fluid pressure. The heat transfer model is based on the three-dimensional, transient heat conduction equation, including heat generation. Boundary conditions include specified temperature and convection. The code was designed with a modular approach so the flow and/or the thermal module may be turned on or off as desired. Both models are solved sequentially in a quasi-steady state fashion. A mesh refinement study was completed on a one-element thick model to determine the recommended size of elements that would result in a converged model for a typical RFI analysis. Guidelines are established for checking the convergence of a model, and the recommended element sizes are listed. Several experiments were conducted and computer simulations of the experiments were run to verify the simulation model. Isothermal, non-reacting flow in a T-stiffened section was simulated to verify the flow module. Predicted infiltration times were within 12-20% of measured times. The predicted pressures were approximately 50% of the measured pressures. A study was performed to attempt to explain the difference in pressures. Non-isothermal experiments with a reactive resin were modeled to verify the thermal module and the resin model. Two panels were manufactured using the RFI process. One was a stepped

  12. Criterion Related Validity of Karate Specific Aerobic Test (KSAT)

    PubMed Central

    Chaabene, Helmi; Hachana, Younes; Franchini, Emerson; Tabben, Montassar; Mkaouer, Bessem; Negra, Yassine; Hammami, Mehrez; Chamari, Karim

    2015-01-01

    Background: Karate is one the most popular combat sports in the world. Physical fitness assessment on a regular manner is important for monitoring the effectiveness of the training program and the readiness of karatekas to compete. Objectives: The aim of this research was to examine the criterion related to validity of the karate specific aerobic test (KSAT) as an indicator of aerobic level of karate practitioners. Patients and Methods: Cardiorespiratory responses, aerobic performance level through both treadmill laboratory test and YoYo intermittent recovery test level 1 (YoYoIRTL1) as well as time to exhaustion in the KSAT test (TE’KSAT) were determined in a total of fifteen healthy international karatekas (i.e. karate practitioners) (means ± SD: age: 22.2 ± 4.3 years; height: 176.4 ± 7.5 cm; body mass: 70.3 ± 9.7 kg and body fat: 13.2 ± 6%). Results: Peak heart rate obtained from KSAT represented ~99% of maximal heart rate registered during the treadmill test showing that KSAT imposes high physiological demands. There was no significant correlation between KSAT’s TE and relative (mL/min kg) treadmill maximal oxygen uptake (r = 0.14; P = 0.69; [small]). On the other hand, there was a significant relationship between KSAT’s TE and the velocity associated with VO2max (vVO2max) (r = 0.67; P = 0.03; [large]) as well as the velocity at VO2 corresponding to the second ventilatory threshold (vVO2 VAT) (r = 0.64; P = 0.04; [large]). Moreover, significant relationship was found between TE’s KSAT and both the total distance covered and parameters of intermittent endurance measured through YoYoIRTL1. Conclusions: The KSAT has not proved to have indirect criterion related validity as no significant correlations have been found between TE’s KSAT and treadmill VO2max. Nevertheless, as correlated to other aerobic fitness variables, KSAT can be considered as an indicator of karate specific endurance. The establishment of the criterion related validity of the KSAT

  13. Effect of Heat Treatment Process on Mechanical Properties and Microstructure of a 9% Ni Steel for Large LNG Storage Tanks

    NASA Astrophysics Data System (ADS)

    Zhang, J. M.; Li, H.; Yang, F.; Chi, Q.; Ji, L. K.; Feng, Y. R.

    2013-12-01

    In this paper, two different heat treatment processes of a 9% Ni steel for large liquefied natural gas storage tanks were performed in an industrial heating furnace. The former was a special heat treatment process consisting of quenching and intercritical quenching and tempering (Q-IQ-T). The latter was a heat treatment process only consisting of quenching and tempering. Mechanical properties were measured by tensile testing and charpy impact testing, and the microstructure was analyzed by optical microscopy, transmission electron microscopy, and x-ray diffraction. The results showed that outstanding mechanical properties were obtained from the Q-IQ-T process in comparison with the Q-T process, and a cryogenic toughness with charpy impact energy value of 201 J was achieved at 77 K. Microstructure analysis revealed that samples of the Q-IQ-T process had about 9.8% of austenite in needle-like martensite, while samples of the Q-T process only had about 0.9% of austenite retained in tempered martensite.

  14. ANAEROBIC AND AEROBIC TREATMENT OF CHLORINATED ALIPHATIC COMPOUNDS

    EPA Science Inventory

    Biological degradation of 12 chlorinated aliphatic compounds (CACs) was assessed in bench-top reactors and in serum bottle tests. Three continuously mixed daily batch-fed reactor systems were evaluated: anaerobic, aerobic, and sequential-anaerobic-aerobic (sequential). Glucose,...

  15. Spinning disc processing technology: potential for large-scale manufacture of chitosan nanoparticles.

    PubMed

    Loh, Jing Wen; Schneider, Jessica; Carter, Michelle; Saunders, Martin; Lim, Lee-Yong

    2010-10-01

    Mass production of nanoparticles using a reliable cost-effective approach is a challenge in the pharmaceutical industry. In this study, the spinning disc processing (SDP) technology was used to fabricate chitosan nanoparticles, with a view to commercially produce chitosan nanoparticle-based drug delivery platforms. Chitosan solution (0.25%, w/v, in dilute acid, 27.5 mL, 1.5 mL/s) was intensely mixed with sodium tripolyphosphate solution (0.10%, w/v, in water, 20 mL, 1.1 mL/s) on the spinning disc (1000 rpm). Transmission electron microscopy and dynamic light scattering data confirmed that the nanoparticles (20 +/- 3 nm) were comparable in size and shape to those synthesised using a beaker and magnetic stirrer (31 +/- 13 nm). Larger nanoparticles (131 +/- 5 nm) were produced by increasing the chitosan and TPP feed concentrations to 0.5% and 0.125%, respectively. Drug loading further increased the size of the nanoparticles, with N-acetyl cysteine (NAC) having a greater effect (403 +/- 4 nm) than paracetamol (165 +/- 4 nm). Co-loading of both drugs increased the size of the particles to the micron range. In conclusion, the SDP is a robust technology capable of expanding the production of blank and drug-loaded chitosan nanoparticles for the biomedical and pharmaceutical industries.

  16. Low cost solution-based materials processing methods for large area OLEDs and OFETs

    NASA Astrophysics Data System (ADS)

    Jeong, Jonghwa

    In Part 1, we demonstrate the fabrication of organic light-emitting devices (OLEDs) with precisely patterned pixels by the spin-casting of Alq3 and rubrene thin films with dimensions as small as 10 mum. The solution-based patterning technique produces pixels via the segregation of organic molecules into microfabricated channels or wells. Segregation is controlled by a combination of weak adsorbing characteristics of aliphatic terminated self-assembled monolayers (SAMs) and by centrifugal force, which directs the organic solution into the channel or well. This novel patterning technique may resolve the limitations of pixel resolution in the method of thermal evaporation using shadow masks, and is applicable to the fabrication of large area displays. Furthermore, the patterning technique has the potential to produce pixel sizes down to the limitation of photolithography and micromachining techniques, thereby enabling the fabrication of high-resolution microdisplays. The patterned OLEDs, based upon a confined structure with low refractive index of SiO2, exhibited higher current density than an unpatterned OLED, which results in higher electroluminescence intensity and eventually more efficient device operation at low applied voltages. We discuss the patterning method and device fabrication, and characterize the morphological, optical, and electrical properties of the organic pixels. In part 2, we demonstrate a new growth technique for organic single crystals based on solvent vapor assisted recrystallization. We show that, by controlling the polarity of the solvent vapor and the exposure time in a closed system, we obtain rubrene in orthorhombic to monoclinic crystal structures. This novel technique for growing single crystals can induce phase shifting and alteration of crystal structure and lattice parameters. The organic molecules showed structural change from orthorhombic to monoclinic, which also provided additional optical transition of hypsochromic shift from

  17. Isolation and characterization of medically important aerobic actinomycetes in soil of iran (2006 - 2007).

    PubMed

    Aghamirian, Mohammad Reza; Ghiasian, Seyed Amir

    2009-01-01

    The aerobic actinomycetes are a large group of soil-inhabiting bacteria that occur worldwide. Some of them are the main cause of two important diseases, nocardiosis and actinomycetoma. To identify the prevalence and geographic distribution of aerobic actinomycetes in soil of Qazvin province, a study was carried out during 2006-2007. In this study, the incidence and diversity of medically important aerobic actinomycetes was determined in 300 soil samples of different parts of Qazvin. The suspensions of superficial soil samples were prepared by adding of normal saline, streptomycin and chloramphenicol and the supernatants were cultured on brain-heart infusion agar and Sabouraud's dextrose agar contain cycloheximide. The isolated microorganisms were examined by Gram and acid-fast stains and were identified biochemically and morphologically. Of 96 aerobic actinomycetes isolates identified, Actinomadura madurae and Streptomyces somaliensis were the most frequently isolated species each representing 19.8% of isolates, followed by Nocardia asteroides (15.6%), N. otitidiscaviarum (9.4%), N. brasiliensis (7.3%), A. peletieri, S. griseus, and Nocardia spp. (each 5.2%), and N. transvalensis, Nocardiopsis dassonvillei, Actinomadura spp. and Streptomyces spp. (each 3.1%). To the best of our knowledge, this is the first report on epidemiological investigation of medically important aerobic actinomycetes in soil samples from Iran. In recent years, mycetoma and nocardiosis have been increasingly reported in Iran. The results showed that medically important actinomycetes occur in the environment of Iran and soil could be potential source of actinomycotic infections.

  18. Comparative investigation on microbial community and electricity generation in aerobic and anaerobic enriched MFCs.

    PubMed

    Quan, Xiang-chun; Quan, Yan-ping; Tao, Kun; Jiang, Xiao-man

    2013-01-01

    This study compared the difference in microbial community and power generation capacity of air-cathode MFCs enriched under anode aerobic and anaerobic conditions. Results showed that MFCs successfully started with continuous air inputting to anode chamber. The aerobic enriched MFC produced comparable and even more electricity with the fuels of acetate, glucose and ethanol compared to the anaerobic MFC when returning to anaerobic condition. The two MFCs showed a slightly different microbial community for anode biofilms (a similarity of 77%), but a highly similar microbial community (a similarity of 97%) for anolyte microbes. The anode biofilm of aerobic enriched MFC showed the presence of some specific bacteria closely related to Clostridium sticklandii, Leucobacter komagatae and Microbacterium laevaniformans. The anaerobic enriched MFC found the presence of a large number of yeast Trichosporon sp. This research demonstrates that it is possible to enrich oxygen-tolerant anode respiring bacteria through purposely aeration in anode chamber.

  19. Stable aerobic granules for continuous-flow reactors: Precipitating calcium and iron salts in granular interiors.

    PubMed

    Juang, Yu-Chuan; Sunil S, Adav; Lee, Duu-Jong; Tay, Joo-Hwa

    2010-11-01

    Aerobic sludge granules are compact, strong microbial aggregates that have excellent settling ability and capability to efficiently treat high-strength and toxic wastewaters. The aerobic granules cultivated with low ammonium and phosphates lost structural stability within 3 days in continuous-flow reactors. Conversely, stable aerobic granules were cultivated in substrate with high levels of ammonium salts that could stably exist for 216 days in continuous-flow reactors with or without submerged membrane. The scanning electron microscopy, energy dispersive spectroscopy microanalysis and the confocal laser scanning microscopy imaging detected large amounts of calcium and iron precipitates in granule interiors. The Visual MINTEQ version 2.61 calculation showed that the phosphates and hydroxides were the main species in the precipitate.

  20. Comparing riparian forest processes on large rivers to inform floodplain management and restoration

    NASA Astrophysics Data System (ADS)

    Stella, J. C.; Piegay, H.; Gruel, C.; Riddle, J.; Raepple, B.

    2014-12-01

    by Acer negundo (box elder), which is non-native and invasive in Europe, suggesting similar processes of colonization and propagation in both systems. Overall, the Sacramento can serve as a predictive reference system for the Rhône, where significant restoration efforts are undeway to improve riparian structure and function in diverted river reaches.

  1. Azo dye treatment with simultaneous electricity production in an anaerobic-aerobic sequential reactor and microbial fuel cell coupled system.

    PubMed

    Li, Zhongjian; Zhang, Xingwang; Lin, Jun; Han, Song; Lei, Lecheng

    2010-06-01

    A microbial fuel cell and anaerobic-aerobic sequential reactor coupled system was used for azo dye degradation with simultaneous electricity production. Electricity was produced during the co-metabolism process of glucose and azo dye. A microorganism cultured graphite-granular cathode effectively decreased the charge transfer resistance of the cathode and yielded higher power density. Operation parameters including glucose concentration and hydraulic retention time were optimized. The results indicated that recovering electricity during a sequential aerobic-anaerobic azo dye treatment process enhanced chemical oxygen demand removal and did not decrease azo dye removal. Moreover, UV-vis spectra and GC-MS illustrated that the azo bond was cleaved biologically in the anaerobic chamber and abiotically in the aerobic chamber. The toxic intermediates, aromatic amines, were removed by aerobic treatment. Our work demonstrated that the microbial fuel cell and sequential anode-cathode reactor coupled system could be applied to achieve electricity production with simultaneous azo dye degradation.

  2. Aerobic Exercise Prescription for Rheumatoid Arthritics.

    ERIC Educational Resources Information Center

    Evans, Blanche W.; Williams, Hilda L.

    The use of exercise as a general treatment for rheumatoid arthritics (RA) has included range of motion, muscular strength, water exercise and rest therapy while virtually ignoring possible benefits of aerobic exercise. The purposes of this project were to examine the guidelines for exercise prescription in relation to this special population and…

  3. Reflections on Psychotherapy and Aerobic Exercise.

    ERIC Educational Resources Information Center

    Silverman, Wade

    This document provides a series of reflections by a practicing psychologist on the uses of aerobic workouts in psychotherapy. Two case histories are cited to illustrate the contention that the mode of exercise, rather than simply its presence or absence, is the significant indicator of a patient's emotional well-being or psychopathology. The first…

  4. AEROBIC DENITRIFICATION: IMPLICATIONS FOR NITROGEN FATE MODELING

    EPA Science Inventory

    In the Mississippi, as well as most nitrogen-degraded rivers and streams, NO3- is the dominant N species and therefore understanding its biogeochemical behavior is critical for accurate nitrogen fate modeling. To our knowledge this is the first work to report aerobic denitrificat...

  5. Aerobic exercise in fibromyalgia: a practical review.

    PubMed

    Thomas, Eric N; Blotman, Francis

    2010-07-01

    The objective of the study was to determine the current evidence to support guidelines for aerobic exercise (AE) and fibromyalgia (FM) in practice, and to outline specific research needs in these areas. Data sources consisted of a PubMed search, 2007 Cochrane Data Base Systematic review, 2008 Ottawa panel evidence-based clinical practice guidelines, as well as additional references found from the initial search. Study selection included randomized clinical trials that compared an aerobic-only exercise intervention (land or pool based) with an untreated control, a non-exercise intervention or other exercise programs in patients responding to the 1990 American College of Rheumatology criteria for FM. The following outcome data were obtained: pain, tender points, perceived improvement in FM symptoms such as the Fibromyalgia Impact Questionnaire total score (FIQ), physical function, depression (e.g., Beck Depression Inventory, FIQ subscale for depression), fatigue and sleep were extracted from 19 clinical trials that considered the effects of aerobic-only exercise in FM patients. Data synthesis shows that there is moderate evidence of important benefit of aerobic-only exercise in FM on physical function and possibly on tender points and pain. It appears to be sufficient evidence to support the practice of AE as a part of the multidisciplinary management of FM. However, future studies must be more adequately sized, homogeneously assessed, and monitored for adherence, to draw definitive conclusions.

  6. Media for the aerobic growth of campylobacter

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The effect of agar and sodium bicarbonate (NaHCO3) concentration on aerobic growth of Campylobacter in a fumarate-pyruvate medium was examined. The broth medium was supplemented with 0.0 to 0.2% agar and inoculated with 106 CFU/ml of Campylobacter coli 33559, Campylobacter fetus 27349, Campylobacter...

  7. Denitrification kinetics in anoxic/aerobic activated sludge systems

    SciTech Connect

    Horne, G.M.

    1998-12-11

    Nitrogen removal needs at municipal wastewater treatment plants (WWTPs) have increased due to greater concerns about eutrophication and increased interest in reuse of treated municipal effluents. Biological processes are the most cost-effective method for nitrogen removal. Biological nitrogen removal is accomplished in two distinctly different processes by the conversion of nitrogen in the wastewater from organic nitrogen and ammonia to nitrate, followed by reduction of the nitrate to nitrogen gas. Nitrate production occurs in an aerobic activated sludge treatment zone during a process called nitrification. The nitrate is then converted through a series of intermediate steps to nitrogen gas in an anoxic zone (an anaerobic condition with nitrate present) during a process called denitrification, effectively removing the nitrogen from the wastewater. Many different WWTP designs have been developed to incorporate these two conditions for nitrogen removal.

  8. Adolescents' Interest and Performances in Aerobic Fitness Testing

    ERIC Educational Resources Information Center

    Zhu, Xihe; Chen, Senlin; Parrott, James

    2014-01-01

    This study examined adolescents' interest in aerobic fitness testing and its relation to the test performances. Adolescents (N = 356) from three middle schools participated in the study. The participants took two aerobic fitness tests: the Progressive Aerobic Cardiovascular Endurance Run (PACER) and One-Mile Run (1MR) with a two-day interval, and…

  9. Ventilation and Speech Characteristics during Submaximal Aerobic Exercise

    ERIC Educational Resources Information Center

    Baker, Susan E.; Hipp, Jenny; Alessio, Helaine

    2008-01-01

    Purpose: This study examined alterations in ventilation and speech characteristics as well as perceived dyspnea during submaximal aerobic exercise tasks. Method: Twelve healthy participants completed aerobic exercise-only and simultaneous speaking and aerobic exercise tasks at 50% and 75% of their maximum oxygen consumption (VO[subscript 2] max).…

  10. Aerobic exercise training in modulation of aerobic physical fitness and balance of burned patients.

    PubMed

    Ali, Zizi M Ibrahim; El-Refay, Basant H; Ali, Rania Reffat

    2015-03-01

    [Purpose] This study aimed to determine the impact of aerobic exercise on aerobic capacity, balance, and treadmill time in patients with thermal burn injury. [Subjects and Methods] Burned adult patients, aged 20-40 years (n=30), from both sexes, with second degree thermal burn injuries covering 20-40% of the total body surface area (TBSA), were enrolled in this trial for 3 months. Patients were randomly divided into; group A (n=15), which performed an aerobic exercise program 3 days/week for 60 min and participated in a traditional physical therapy program, and group B (n=15), which only participated in a traditional exercise program 3 days/week. Maximal aerobic capacity, treadmill time, and Berg balance scale were measured before and after the study. [Results] In both groups, the results revealed significant improvements after treatment in all measurements; however, the improvement in group A was superior to that in group B. [Conclusion] The results provide evidence that aerobic exercises for adults with healed burn injuries improve aerobic physical fitness and balance.

  11. Near-Space TOPSAR Large-Scene Full-Aperture Imaging Scheme Based on Two-Step Processing

    PubMed Central

    Zhang, Qianghui; Wu, Junjie; Li, Wenchao; Huang, Yulin; Yang, Jianyu; Yang, Haiguang

    2016-01-01

    Free of the constraints of orbit mechanisms, weather conditions and minimum antenna area, synthetic aperture radar (SAR) equipped on near-space platform is more suitable for sustained large-scene imaging compared with the spaceborne and airborne counterparts. Terrain observation by progressive scans (TOPS), which is a novel wide-swath imaging mode and allows the beam of SAR to scan along the azimuth, can reduce the time of echo acquisition for large scene. Thus, near-space TOPS-mode SAR (NS-TOPSAR) provides a new opportunity for sustained large-scene imaging. An efficient full-aperture imaging scheme for NS-TOPSAR is proposed in this paper. In this scheme, firstly, two-step processing (TSP) is adopted to eliminate the Doppler aliasing of the echo. Then, the data is focused in two-dimensional frequency domain (FD) based on Stolt interpolation. Finally, a modified TSP (MTSP) is performed to remove the azimuth aliasing. Simulations are presented to demonstrate the validity of the proposed imaging scheme for near-space large-scene imaging application. PMID:27472341

  12. Near-Space TOPSAR Large-Scene Full-Aperture Imaging Scheme Based on Two-Step Processing.

    PubMed

    Zhang, Qianghui; Wu, Junjie; Li, Wenchao; Huang, Yulin; Yang, Jianyu; Yang, Haiguang

    2016-07-27

    Free of the constraints of orbit mechanisms, weather conditions and minimum antenna area, synthetic aperture radar (SAR) equipped on near-space platform is more suitable for sustained large-scene imaging compared with the spaceborne and airborne counterparts. Terrain observation by progressive scans (TOPS), which is a novel wide-swath imaging mode and allows the beam of SAR to scan along the azimuth, can reduce the time of echo acquisition for large scene. Thus, near-space TOPS-mode SAR (NS-TOPSAR) provides a new opportunity for sustained large-scene imaging. An efficient full-aperture imaging scheme for NS-TOPSAR is proposed in this paper. In this scheme, firstly, two-step processing (TSP) is adopted to eliminate the Doppler aliasing of the echo. Then, the data is focused in two-dimensional frequency domain (FD) based on Stolt interpolation. Finally, a modified TSP (MTSP) is performed to remove the azimuth aliasing. Simulations are presented to demonstrate the validity of the proposed imaging scheme for near-space large-scene imaging application.

  13. The relationship between aerobic fitness and neural oscillations during visuo-spatial attention in young adults.

    PubMed

    Wang, Chun-Hao; Liang, Wei-Kuang; Tseng, Philip; Muggleton, Neil G; Juan, Chi-Hung; Tsai, Chia-Liang

    2015-04-01

    While the cognitive benefits of aerobic fitness have been widely investigated, current findings in young adults remain unclear. Specifically, little is known about how these effects are reflected in the time-frequency domain. This study thus assessed the relationship between aerobic fitness and neural oscillations during visuo-spatial attention. A between-subjects design that included 20 participants with higher aerobic fitness (age = 21.95 ± 2.24 years; VO2max = 58.98 ± 6.94 ml/kg/min) and 20 age- and gender-matched lower aerobic fitness participants (age = 23.25 ± 2.07 years; VO2max = 35.87 ± 3.41 ml/kg/min) was used to examine the fitness-related differences in performance and neuroelectric indexes during a Posner visuo-spatial attention paradigm. The results demonstrated that high-fitness participants, in comparison with their low-fitness counterparts, showed faster reaction times as well as greater modulation of oscillatory theta and beta power during target processing, regardless of cue types. Moreover, the neurocognitive correlation showed that higher theta power was related to better task performance. Collectively, these findings suggest that aerobic fitness is associated with general enhanced attentional control in relation to visuo-spatial processing, as evidenced through greater motor preparation and in particular the up-regulation of attentional processing in healthy young adults. The present study may contribute to current knowledge by revealing the relationship between aerobic fitness and modulation of brain oscillations.

  14. Detection of Thermometer Clustering in the Calibration of Large Batches of Industrial Thermometers for the LHC by Automated Data Processing

    NASA Astrophysics Data System (ADS)

    Pavese, F.; Ichim, D.; Ciarlini, P.; Balle, C.; Casas-Cubillos, J.

    2003-09-01

    The complete procedure to calibrate thermometers is a complex process, especially when several thousand semiconductor-type thermometers are used and must be individually calibrated, as in the case of the instrumentation of the new Large Hadron Collider (LHC) machine at CERN. Indeed, the similarity of the characteristics of semiconducting thermometers is more limited than that of wire-wound thermometers. The span of the characteristics spread can appear as a homogeneous set, or can show clusters (groups) of characteristics. In the latter case, one of the reasons for clustering may be the fabrication process by batches of numerous devices on the same wafer. Consequently, the detection of the groups can be useful, from the supplier point of view, to give information relevant to improving the fabrication uniformity. From the user point of view, it is useful for making a guess of the possible thermometer stability with time, when this is a must, as in the LHC case. In fact, thermometers showing characteristics outlying or in small clusters should be considered to be potentially anomalous. In addition, the identification of anomalous groups allows the detection of artifacts due to the experimental process. For a large number of thermometers, this analysis requires the use of automated procedures and, consequently, automated decisions that avoid false effects. The paper describes the mathematical methodology adopted for the identification of the clusters, based on the mixed-effect modeling of the thermometer characteristics.

  15. Preliminary study on aerobic granular biomass formation with aerobic continuous flow reactor

    NASA Astrophysics Data System (ADS)

    Yulianto, Andik; Soewondo, Prayatni; Handajani, Marissa; Ariesyady, Herto Dwi

    2017-03-01

    A paradigm shift in waste processing is done to obtain additional benefits from treated wastewater. By using the appropriate processing, wastewater can be turned into a resource. The use of aerobic granular biomass (AGB) can be used for such purposes, particularly for the processing of nutrients in wastewater. During this time, the use of AGB for processing nutrients more reactors based on a Sequencing Batch Reactor (SBR). Studies on the use of SBR Reactor for AGB demonstrate satisfactory performance in both formation and use. SBR reactor with AGB also has been applied on a full scale. However, the use use of SBR reactor still posses some problems, such as the need for additional buffer tank and the change of operation mode from conventional activated sludge to SBR. This gives room for further reactor research with the use of a different type, one of which is a continuous reactor. The purpose of this study is to compare AGB formation using continuous reactor and SBR with same operation parameter. Operation parameter are Organic Loading Rate (OLR) set to 2,5 Kg COD/m3.day with acetate as substrate, aeration rate 3 L/min, and microorganism from Hospital WWTP as microbial source. SBR use two column reactor with volumes 2 m3, and continuous reactor uses continuous airlift reactor, with two compartments and working volume of 5 L. Results from preliminary research shows that although the optimum results are not yet obtained, AGB can be formed on the continuous reactor. When compared with AGB generated by SBR, then the characteristics of granular diameter showed similarities, while the sedimentation rate and Sludge Volume Index (SVI) characteristics showed lower yields.

  16. Multi-format all-optical processing based on a large-scale, hybridly integrated photonic circuit.

    PubMed

    Bougioukos, M; Kouloumentas, Ch; Spyropoulou, M; Giannoulis, G; Kalavrouziotis, D; Maziotis, A; Bakopoulos, P; Harmon, R; Rogers, D; Harrison, J; Poustie, A; Maxwell, G; Avramopoulos, H

    2011-06-06

    We investigate through numerical studies and experiments the performance of a large scale, silica-on-silicon photonic integrated circuit for multi-format regeneration and wavelength-conversion. The circuit encompasses a monolithically integrated array of four SOAs inside two parallel Mach-Zehnder structures, four delay interferometers and a large number of silica waveguides and couplers. Exploiting phase-incoherent techniques, the circuit is capable of processing OOK signals at variable bit rates, DPSK signals at 22 or 44 Gb/s and DQPSK signals at 44 Gbaud. Simulation studies reveal the wavelength-conversion potential of the circuit with enhanced regenerative capabilities for OOK and DPSK modulation formats and acceptable quality degradation for DQPSK format. Regeneration of 22 Gb/s OOK signals with amplified spontaneous emission (ASE) noise and DPSK data signals degraded with amplitude, phase and ASE noise is experimentally validated demonstrating a power penalty improvement up to 1.5 dB.

  17. Comparative studies of aerobic and anaerobic biodegradation of methylparaben and propylparaben in activated sludge.

    PubMed

    Wu, Yang; Sun, Qian; Wang, Yu-Wen; Deng, Cheng-Xun; Yu, Chang-Ping

    2017-04-01

    The biodegradability of two typical parabens (methylparaben and propylparaben) in activated sludge, at initial concentrations of 1mgL(-1) or 10mgL(-1), was investigated under aerobic and anaerobic conditions. The results showed that microorganisms played a key role in degradation of parabens in WWTPs, especially in aerobic systems. The half-lives of methylparaben and propylparaben under aerobic conditions have been estimated to range between 15.8 and 19.8min, and benzoic acid was found to be one of the major biodegradation products. The calculated biodegradation efficiency of methylparaben and propylparaben in activated sludge under aerobic conditions was significantly higher than that observed under anaerobic (nitrate, sulfate, and Fe (III) reducing) conditions, as methylparaben and propylparaben exhibited comparatively higher persistence in anaerobic systems, with half-lives ≥43.3h and ≥8.6h, respectively. Overall, the results of this study imply that the majority of these parabens can be eliminated by aerobic biodegradation during conventional wastewater treatment processes, whereas minor removal is possible in anaerobic systems if an insufficient hydraulic retention time was maintained.

  18. Nitrogen removal in an upflow sludge blanket (USB) reactor combined by aerobic biofiltration systems.

    PubMed

    Jun, H B; Park, S M; Park, J K; Choi, C O; Lee, J S

    2004-01-01

    A new nitrogen removal process (up-flow sludge blanket and aerobic filter, USB-AF) was proposed and tested with real sewage. In the USB reactor, the larger part of influent organic and nitrogen matters were removed, and ammonia was effectively oxidized in the subsequent aerobic filter. The role of the aerobic filter was to convert ammonia into nitrate, an electron acceptor that could convert soluble organic matters into volatile suspended solid (VSS) in the USB. The accumulated as well as influent VSS in the USB was finally degraded to fermented products that were another good carbon source for denitrification. Total COD, settleable COD and soluble COD in the raw sewage were 325, 80 and 140 mg/l, respectively. Most unsettleable COD as well as some SCOD in the influent was successfully removed in the USB. TCOD removal in the anoxic filter was by denitrification with the recycled nitrate. Low COD input to the aerobic filter could increase nitrification efficiency, reduce the start-up period and save the aeration energy in the USB-AF system. About 95% of ammonia was nitrified in the aerobic filter with no relation to the influent ammonia concentration. Denitrification efficiency of the recycled nitrate in the anoxic filter was about 85, 83, and 72% at recycle ratios of 100, 200, and 300%, respectively. T-N removal efficiency was 70% at recycle ratio of 300%.

  19. Effect of NaCl on aerobic denitrification by strain Achromobacter sp. GAD-3.

    PubMed

    Gui, Mengyao; Chen, Qian; Ni, Jinren

    2017-03-01

    This paper presents the effect of NaCl on aerobic denitrification by a novel aerobic denitrifier strain Achromobacter sp. GAD-3. Results indicated that the aerobic denitrification process was inhibited by NaCl concentrations ≥20 g L(-1), leading to lower nitrate removal rates (1.67∼4.0 mg L(-1) h(-1)), higher nitrite accumulation (50.2∼87.4 mg L(-1)), and increasing N2O emission ratios (13∼72 mg L(-1)/mg L(-1)). Poor performance of aerobic denitrification at high salinity was attributed to the suppression of active microbial biomass and electron donating capacity of strain GAD-3. Further studies on the corresponding inhibition of the denitrifying gene expression by higher salinities revealed the significant sensitivity order of nosZ (for N2O reductase) > cnorB (for NO reductase) ≈ nirS (for cytochrome cd(1) nitrite reductase) > napA (for periplasmic nitrate reductase), accompanied with a time-lapse expression between nosZ and cnorB based on reverse transcription and real-time quantitative polymerase chain reaction (RT-qPCR) analysis. The insights into the effect of NaCl on aerobic denitrification are of great significance to upgrade wastewater treatment plants (WWTPs) containing varying levels of salinity.

  20. New records in aerobic power among octogenarian lifelong endurance athletes

    PubMed Central

    Hayes, Erik; Galpin, Andrew; Kaminsky, Leonard; Jemiolo, Bozena; Fink, William; Trappe, Todd; Jansson, Anna; Gustafsson, Thomas; Tesch, Per

    2013-01-01

    We examined whole body aerobic capacity and myocellular markers of oxidative metabolism in lifelong endurance athletes [n = 9, 81 ± 1 yr, 68 ± 3 kg, body mass index (BMI) = 23 ± 1 kg/m2] and age-matched, healthy, untrained men (n = 6; 82 ± 1 y, 77 ± 5 kg, BMI = 26 ± 1 kg/m2). The endurance athletes were cross-country skiers, including a former Olympic champion and several national/regional champions, with a history of aerobic exercise and participation in endurance events throughout their lives. Each subject performed a maximal cycle test to assess aerobic capacity (V̇o2max). Subjects had a resting vastus lateralis muscle biopsy to assess oxidative enzymes (citrate synthase and βHAD) and molecular (mRNA) targets associated with mitochondrial biogenesis [peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) and mitochondrial transcription factor A (Tfam)]. The octogenarian athletes had a higher (P < 0.05) absolute (2.6 ± 0.1 vs. 1.6 ± 0.1 l/min) and relative (38 ± 1 vs. 21 ± 1 ml·kg−1·min−1) V̇o2max, ventilation (79 ± 3 vs. 64 ± 7 l/min), heart rate (160 ± 5 vs. 146 ± 8 beats per minute), and final workload (182 ± 4 vs. 131 ± 14 W). Skeletal muscle oxidative enzymes were 54% (citrate synthase) and 42% (βHAD) higher (P < 0.05) in the octogenarian athletes. Likewise, basal PGC-1α and Tfam mRNA were 135% and 80% greater (P < 0.05) in the octogenarian athletes. To our knowledge, the V̇o2max of the lifelong endurance athletes is the highest recorded in humans >80 yr of age and comparable to nonendurance trained men 40 years younger. The superior cardiovascular and skeletal muscle health profile of the octogenarian athletes provides a large functional reserve above the aerobic frailty threshold and is associated with lower risk for disability and mortality. PMID:23065759