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Sample records for af soomaali spanish

  1. Health Information in Somali (af Soomaali): MedlinePlus

    MedlinePlus

    ... af Soomaali (Somali) Bilingual PDF Health Information Translations Tornadoes Sirens and Telephone Alerts - English Firimbiyada iyo Digniinaha telefonka - af Soomaali (Somali) PDF Healthy Roads Media Tornadoes - English Dabayl xoog badan (Ufo) - af Soomaali (Somali) ...

  2. HPV - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Creole (Kreyol) Hmong (Hmoob) Khmer (Khmer) Korean (한국어) Oromo (Afaan Oromo) Russian (Русский) Somali (af Soomaali) Spanish (español) Tagalog ( ... Action Coalition; Centers for Disease Control and Prevention Oromo (Afaan Oromo) Genital Warts/HPV English Biqiltuwwan Dhagna- ...

  3. Tuberculosis - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Japanese (日本語) Khmer (Khmer) Korean (한국어) Laotian (Lao) Oromo (Afaan Oromo) Portuguese (português) Russian (Русский) Somali (af Soomaali) Spanish ( ... English Lao (Laotian) PDF Minnesota Department of Health Oromo (Afaan Oromo) Active TB Disease English Dhukkuba Sombaa ...

  4. Sexually Transmitted Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Oromo (Afaan Oromo) Portuguese (português) Russian (Русский) Somali (af Soomaali) Spanish ( ... 질환 - 한국어 (Korean) Bilingual PDF Health Information Translations Oromo (Afaan Oromo) Chancroid English Murmuraa - Afaan Oromo (Oromo) ...

  5. Diabetic Kidney Problems - Multiple Languages: MedlinePlus

    MedlinePlus

    ... XYZ List of All Topics All Diabetic Kidney Problems - Multiple Languages To use the sharing features on this page, please enable JavaScript. Arabic (العربية) Russian (Русский) Somali (af Soomaali) Spanish (español) Arabic (العربية) Diabetes and Kidney Problems (Arabic) ...

  6. Diabetic Nerve Problems - Multiple Languages: MedlinePlus

    MedlinePlus

    ... XYZ List of All Topics All Diabetic Nerve Problems - Multiple Languages To use the sharing features on this page, please enable JavaScript. Arabic (العربية) Russian (Русский) Somali (af Soomaali) Spanish (español) Arabic (العربية) Diabetes and Nerve Damage (Arabic) ...

  7. Living with HIV/AIDS - Multiple Languages: MedlinePlus

    MedlinePlus

    ... sharing features on this page, please enable JavaScript. French (français) Karen (Sgaw Karen) Nepali (नेपाली) Somali (af Soomaali) Spanish (español) Swahili (Kiswahili) French (français) Sharing Your HIV Status English Communiquer son ...

  8. HIV/AIDS and Infections - Multiple Languages: MedlinePlus

    MedlinePlus

    ... sharing features on this page, please enable JavaScript. French (français) Karen (Sgaw Karen) Nepali (नेपाली) Somali (af Soomaali) Spanish (español) Swahili (Kiswahili) French (français) Opportunistic Infections English Infections opportunistes - français (French) ...

  9. Spanish, Si!

    ERIC Educational Resources Information Center

    Cage, Mary Crystal

    1994-01-01

    College language departments report that, although enrollments in Spanish and some Pacific Rim languages are growing rapidly, declines are seen in French and German, traditionally popular, and in many less commonly taught languages. Students are motivated by practical considerations: many find their employment potential is increased by language…

  10. For Spanish Readers.

    ERIC Educational Resources Information Center

    Rivas, Yolanda

    1979-01-01

    Lists and discusses children's books written in Spanish or translated into Spanish from English. Also describes a recording consisting of an anthology of Spanish poetry and folklore for children. (GT)

  11. Asthma in Children - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Arabic (العربية) Chinese - Simplified (简体中文) Chinese - Traditional (繁體中文) Japanese (日本語) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 繁體中文 (Chinese - Traditional) Bilingual PDF Health Information Translations Japanese (日本語) Nebulizer Treatments ネブライザー療法 - 日本語 (Japanese) Bilingual PDF ...

  12. Fires - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Bosanski) Somali (af Soomaali) Spanish (español) Arabic (العربية) Wildfires English (Arabic) حرائق الغابات - العربية Multimedia Healthy Roads Media Wildfires English (Arabic) حرائق الغابات - العربية PDF Healthy Roads ...

  13. Diabetic Eye Problems - Multiple Languages: MedlinePlus

    MedlinePlus

    ... français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Portuguese (português) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 망막증 - 한국어 (Korean) Bilingual PDF Health Information Translations Portuguese (português) Diabetic Retinopathy Retinopatia Diabética - português (Portuguese) Bilingual ...

  14. Vascular Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 血管疾患 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Angiogram 혈관 조영 검사 - 한국어 (Korean) Bilingual ...

  15. Bone Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 骨スキャン - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Bone Scan 골 (骨) 스캔 - 한국어 (Korean) ...

  16. Baby Health Checkup - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 子供のかかりつけ医の選択 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Choosing a Doctor for Your Baby 아기를 ...

  17. Brain Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 脳スキャン検査 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Brain Scan 뇌 스캔 - 한국어 (Korean) Bilingual ...

  18. Arthritis - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 简体中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 関節炎 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Arthritis 관절염 - 한국어 (Korean) Bilingual PDF Health ...

  19. Back Pain - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 简体中文) Chinese - Traditional (繁體中文) French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 背中のための体操 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Exercises for Your Back 허리운동 - 한국어 (Korean) ...

  20. Concussion - Multiple Languages: MedlinePlus

    MedlinePlus

    ... page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 脳の損傷の種類 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Types of Brain Injury 뇌손상의 종류 - 한국어 ( ...

  1. Constipation - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 便秘 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Constipation 변비 - 한국어 (Korean) Bilingual PDF Health ...

  2. Traumatic Brain Injury - Multiple Languages: MedlinePlus

    MedlinePlus

    ... page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 脳の損傷の種類 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Brain Scan 뇌 스캔 - 한국어 (Korean) Bilingual ...

  3. Bone Marrow Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 骨髄生検 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Bone Marrow Biopsy 골수 생체조직 검사 - 한국어 ( ...

  4. Dementia - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 認知症の種類 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Legal Plans: Assisting the Person with Dementia ...

  5. Burns - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 火傷のケア - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Burn Care 화상 관리 - 한국어 (Korean) Bilingual ...

  6. Spanish for Spanish-Speaking Students.

    ERIC Educational Resources Information Center

    Fuentes, Irma; And Others

    This curriculum bulletin, completely in Spanish, is intended to serve as a guide to teaching Spanish and the culture of Spain and the Latin-American countries to students who come from Spanish-speaking homes. The bulletin presents an accelerated course of study for the first year and includes the vocabulary idiomatic expressions, and structures…

  7. For Spanish Readers.

    ERIC Educational Resources Information Center

    Rivas, Yolanda

    1979-01-01

    Reviews eight children's books written in Spanish and one written in both Spanish and English. One is a book of riddles; the others deal with the topics of animals, minerals, plants and flowers, Indians, and pirates. (GT)

  8. For Spanish Readers.

    ERIC Educational Resources Information Center

    Rivas, Yolanda

    1980-01-01

    Lists and annotates four picture books (three by classic Russian poets) that have been translated from Russian into Spanish, and two nonfiction books about handicapped children that have been translated from English to Spanish. (GT)

  9. Studies in Southwest Spanish.

    ERIC Educational Resources Information Center

    Bowen, J. Donald, Ed.; Ornstein, Jacob, Ed.

    The Spanish dialects of the Southwest United States have received little serious attention until recently. The present volume contains studies designed to contribute to the understanding and acceptance of Southwest Spanish. The book consists of the following chapters: (1) "Linguistic Diversity in Southwest Spanish," by Garland D. Bills and Jacob…

  10. Secondary School Languages: Spanish.

    ERIC Educational Resources Information Center

    British Columbia Dept. of Education, Victoria.

    This curriculum guide outlines three programs for secondary school Spanish instruction, each program covering grades 9, 10, and 11 in British Columbian schools. Each outline specifies basic texts, supplementary readings, and teaching aids. In addition, a very basic outline of a beginner's Spanish 11 is offered, and a Spanish 12 literature course…

  11. The AFS Impact Study: Final Report. AFS Research Report 33.

    ERIC Educational Resources Information Center

    Hansel, Bettina

    The AFS Impact Study, initiated in 1977, is an attempt to document changes in learning and personal development associated with an intercultural "homestay" program. Completed in 1985, the study identifies several areas in which students show greater learning and educational growth than that shown by a group of students who had expressed interest…

  12. Spanish labeling guide.

    PubMed

    Juliá, A M; García, S V; Breckinridge, M F

    1983-01-01

    A systematic reference of English-Spanish prescription label translations is presented. The purpose of the reference list (which is the most comprehensive published to date) is to enable a pharmacist to write precise, accurate label directions in Spanish for any patient who cannot read English.

  13. SPANISH IN THE SOUTHWEST.

    ERIC Educational Resources Information Center

    SANCHEZ, GEORGE I.

    IN THE AMERICAN SOUTHWEST, FOUR MILLION SPANISH-AMERICANS ARE CONCENTRATED IN FIVE STATES. THEIR CULTURAL TENACITY IS A PECULIARITY NOT DISPLAYED BY OTHER IMMIGRANT GROUPS. EVEN AFTER 125 YEARS THEY SPEAK AND LIVE IN A SPANISH-AMERICAN SOCIETY. THE REASON FOR THIS IS DIFFICULT TO DISCERN, BUT IT IS FELT BY SOME THAT THIS TENACITY IS VERY NOBLE AND…

  14. Spanish Special Purpose Dictionaries.

    ERIC Educational Resources Information Center

    Champion, James J.

    1982-01-01

    A variety of special purpose Spanish dictionaries available for students of Spanish are described, including dictionaries of groupings of associated words, technical language, regional and slang language, single authors' usage, historical periods, etymology, frequency, and reverse organization. Several illustrations of dictionary organization are…

  15. Teaching Spanish to the Spanish Speaking: Theory and Practice.

    ERIC Educational Resources Information Center

    Valdes Fallis, Guadalupe, Ed.; Garcia-Moya, Rudolfo, Ed.

    This volume gathers a sampling of educators' ideas on the issue of the role of the non-standard dialect in the teaching of Spanish to Spanish speakers. Part one, "Rationale for the Teaching of Spanish to the Spanish Speaking," deals with philosophy and theory and contains papers by Guadalupe Valdes Fallis and Nasario Garcia. Part two, "Linguistic…

  16. Teaching L2 Spanish Stress

    ERIC Educational Resources Information Center

    Saalfeld, Anita K.

    2012-01-01

    The present study investigated the effects of training on the perception of Spanish stress, an important feature in the Spanish verbal morphology system. Participants were two intact classes of native English speakers enrolled in a six-week session of second-semester Spanish, as well as native English and native Spanish control groups. During the…

  17. Eaton AF5000+Genesis Communication Driver

    1995-05-25

    Communication driver allows the Genesis Control Series software to interact with Eaton AF5000+ frequency drives via RS-232 communications. All Eaton AF5000+ parameters that support communications are supported by the Genesis driver. Multidrop addressing to multiple units is available with the Genesis communication driver.

  18. Baseball/Beisbol. Spanish-English, English-Spanish. Revised.

    ERIC Educational Resources Information Center

    Grosse, Philip

    The bilingual glossary, in both English-to-Spanish and Spanish-to-English, defines words and phrases related to the game of baseball as it is reported by Spanish-language newspapers and magazines in Mexico and the United States. A list of U.S. and Mexican baseball league teams is appended. (MSE)

  19. Spanish? What Spanish? The Search for a 'Caribbean Standard.'

    ERIC Educational Resources Information Center

    Hollingsworth, C.

    1978-01-01

    Variations in lexicon, phonology, morphology, and syntax of Spanish as spoken in Venezuela, Cuba, Mexico, and Castile have led to a diversity in the types of Spanish taught in Caribbean schools. The Programa Interamericano de Linguistica y Ensenanza de Idiomas is conducting a survey which will provide authoritative standards for Spanish teachers.…

  20. Cultural Understanding: Spanish Level 1.

    ERIC Educational Resources Information Center

    Scott, Reid

    The teacher's attention is focused on selected elements of Spanish culture which may be taught integrally with instructional materials found in the first-year Spanish texts "Entender y Hablar", "La Familia Fernandez", and "A-LM Spanish, Level One". Items are cross-referenced for 42 cultural concepts ranging from nicknames to streets, roads, and…

  1. Noteworthy Children's Books in Spanish.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2000-01-01

    Provides a list of recently published children's books in Spanish for Spanish-speaking children or students learning Spanish as a second or foreign language. The list is divided into one section for very young children and another for middle grade students. Information is also given about a Web site where users can access a searchable database of…

  2. Coronary Artery Bypass Surgery - Multiple Languages: MedlinePlus

    MedlinePlus

    ... 繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 冠動脈バイパス手術 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Coronary Artery Bypass Surgery 관상동맥 우회 수술 - ...

  3. Anal Disorders - Multiple Languages: MedlinePlus

    MedlinePlus

    ... العربية) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... バリウム注腸 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Barium Enema 바륨 관장검사 - 한국어 (Korean) Bilingual ...

  4. Breathing Problems - Multiple Languages: MedlinePlus

    MedlinePlus

    ... JavaScript. French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... スパイロメーター - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Incentive Spirometer 유발성 폐활량계 - 한국어 (Korean) Bilingual ...

  5. Colonic Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... العربية) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... バリウム注腸 - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) Barium Enema 바륨 관장검사 - 한국어 (Korean) Bilingual ...

  6. Bile Duct Diseases - Multiple Languages: MedlinePlus

    MedlinePlus

    ... page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) Spanish (español) ... 内視鏡的逆行性胆道膵管造影法) - 日本語 (Japanese) Bilingual PDF Health Information Translations Korean (한국어) ERCP (Endoscopic Retrograde Cholangiopancreatography) 퇴행성 담도췌관조영술 내시경 ...

  7. Know Your Laws. Spanish.

    ERIC Educational Resources Information Center

    Watson, Joan Q.; Ackerson, Leonor

    This Spanish language version of "Know Your Laws" consists of 24 self-contained modules designed to acquaint the Florida adult student with laws she/he will meet in everyday life; fundamentals of local, state, and federal governments; and the criminal and juvenile justice systems. (The 130 objectives are categorized in the first three levels of…

  8. Spanish Consensus Statement

    PubMed Central

    Rey, Guillermo Álvarez; Cuesta, Jordi Ardevol; Loureda, Rafael Arriaza; España, Fernando Ávila; Matas, Ramón Balius; Pazos, Fernando Baró; de Dios Beas Jiménez, Juan; Rosell, Jorge Candel; Fernandez, César Cobián; Ros, Francisco Esparza; Colmenero, Josefina Espejo; de Prado, Jorge Fernández; Cota, Juan José García; González, Jose Ignacio Garrido; Santander, Manuela González; Munilla, Miguel Ángel Herrador; Ruiz, Francisco Ivorra; Díaz, Fernando Jiménez; Marqueta, Pedro Manonelles; Fernandez, Antonio Maestro; Benito, Juan José Muñoz; Vilás, Ramón Olivé; Teres, Xavier Peirau; Amaro, José Peña; Roque, Juan Pérez San; Parenteu, Christophe Ramírez; Serna, Juan Ribas; Álvarez, Mikel Sánchez; Marchori, Carlos Sanchez; Soto, Miguel del Valle; Alonso, José María Villalón; García, Pedro Guillen; de la Iglesia, Nicolas Hugo; Alcorocho, Juan Manuel Lopez

    2016-01-01

    On the 21st of March, 2015, experts met at Clínica CEMTRO in Madrid, Spain, under the patronage of The Spanish Society for Sports Traumatology (SETRADE), The Spanish Federation of Sports Medicine (FEMEDE), The Spanish Association of Medical Services for Football Clubs (AEMEF), and The Spanish Association of Medical Services for Basketball Clubs (AEMB) with the aim of establishing a round table that would allow specialists to consider the most appropriate current general actions to be taken when treating muscle tears in sport, based on proven scientific data described in the medical literature. Each expert received a questionnaire prior to the aforementioned meeting comprising a set of questions concerning therapeutic indications generally applied in the different stages present during muscle repair. The present Consensus Document is the result of the answers to the questionnaire and resulting discussion and consensus over which are the best current indications in the treatment of muscle tears in sport. Avoiding immobilization, not taking nonsteroidal anti-inflammatory drugs (NSAIDs) randomly, fostering early mobilization, increasing vascularization of injured, site and regulating inflammatory mechanisms—without inhibiting these from the early stages of the recovery period—all stood out as main points of the Consensus Document. Additionally, there is controversy concerning cell stimulation techniques and the use of growth factors or cell inhibitors. The decision concerning discharge was unanimous, as was the criteria considered when it came to performing sport techniques without pain. PMID:27213161

  9. Spanish Curriculum Guide.

    ERIC Educational Resources Information Center

    Wicklund, Jacqueline

    This guide delineates the scope and sequence of Spanish instruction in both junior and senior high schools indicating instructional goals in terms of behavioral objectives. Following a review of the Bloomington, Minnesota, school of philosophy and a discussion of the design of the foreign language behavioral objectives in the guide, the manual…

  10. The Spanish Texans.

    ERIC Educational Resources Information Center

    Texas Univ., San Antonio. Inst. of Texan Cultures.

    Prepared by the staff of the University of Texas Institute of Texan Cultures at San Antonio, this pamphlet is one of a series which reports contributions made by ethnic groups to the history and culture of Texas. Specifically, historical incidents involving Spanish explorers and missionaries are discussed, relating their contributions to Texas.…

  11. Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success

    PubMed Central

    Choi, Eue-Keun; Park, Jae Hyung; Lee, Ji-Young; Nam, Chung Mo; Hwang, Min Ki; Uhm, Jae-Sun; Joung, Boyoung; Ko, Young-Guk; Lee, Moon-Hyoung; Lubitz, Steven A; Ellinor, Patrick T; Pak, Hui-Nam

    2015-01-01

    Background Genomewide association studies have identified several loci associated with atrial fibrillation (AF) and have been reportedly associated with response to catheter ablation for AF in patients of European ancestry; however, associations between top susceptibility loci and AF recurrence after ablation have not been examined in Asian populations. We examined whether the top single nucleotide polymorphisms (SNPs) at chromosomes 4q25 (PITX2), 16q22 (ZFHX3), and 1q21 (KCNN3) were associated with AF in a Korean population and whether these SNPs were associated with clinical outcomes after catheter ablation for AF. Methods and Results We determined the association between 4 SNPs and AF in 1068 AF patients who underwent catheter ablation (74.6% male, aged 57.5±10.9 years, 67.9% paroxysmal AF) and 1068 age- and sex-matched controls. The SNPs at the PITX2 and ZFHX3 loci, but not the KCNN3 locus, were significantly associated with AF (PITX2/rs6843082_G: odds ratio 3.41, 95% CI 2.55 to 4.55, P=1.32×10−16; PITX2/rs2200733_T: odds ratio 2.05, 95% CI 1.66 to 2.53, P=2.20×10−11; ZFHX3/rs2106261_A: odds ratio 2.33, 95% CI 1.87 to 2.91, P=3.75×10−14; KCNN3/rs13376333_T: odds ratio 1.74, 95% CI 0.93 to 3.25, P=0.085). Among those patients who underwent catheter ablation for AF, none of the top AF-associated SNPs were associated with long-term clinical recurrence of AF after catheter ablation. Conclusions SNPs at the PITX2 and ZFHX3 loci were strongly associated with AF in Korean patients. In contrast to prior reports, none of the 4 top AF-susceptibility SNPs predicted clinical recurrence after catheter ablation. PMID:26272656

  12. Microvariation in Accentual Alignment in Basque Spanish

    ERIC Educational Resources Information Center

    Elordieta, Gorka; Calleja, Nagore

    2005-01-01

    This paper presents patterns of accentual alignment in two varieties of Spanish spoken in the Basque Country: Lekeitio Spanish (LS), with speakers whose other native language is Lekeitio Basque (LB); and Vitoria Spanish (VS), with monolingual speakers of Spanish from the city of Vitoria. These patterns are compared to those of Madrid Spanish (MS),…

  13. 7 CFR 51.2734 - Spanish type.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Spanish type. 51.2734 Section 51.2734 Agriculture... Standards for Grades of Shelled Spanish Type Peanuts Definitions § 51.2734 Spanish type. Spanish type means peanuts of varieties which belong to the Spanish classification group and which are free from kernels...

  14. "Castellano" y "Espanol" (Castilian and Spanish)

    ERIC Educational Resources Information Center

    Diaz-Plaja, Guillermo

    1977-01-01

    Argues that the term "Castilian" should replace "Spanish" to denote the Castilian form of the language. "Spanish" may then be a more inclusive term, enbracing all the dialects of the language. (Text is in Spanish.) (CHK)

  15. Degradation of AF1Q by chaperone-mediated autophagy

    SciTech Connect

    Li, Peng; Ji, Min; Lu, Fei; Zhang, Jingru; Li, Huanjie; Cui, Taixing; Li Wang, Xing; Tang, Dongqi; Ji, Chunyan

    2014-09-10

    AF1Q, a mixed lineage leukemia gene fusion partner, is identified as a poor prognostic biomarker for pediatric acute myeloid leukemia (AML), adult AML with normal cytogenetic and adult myelodysplastic syndrome. AF1Q is highly regulated during hematopoietic progenitor differentiation and development but its regulatory mechanism has not been defined clearly. In the present study, we used pharmacological and genetic approaches to influence chaperone-mediated autophagy (CMA) and explored the degradation mechanism of AF1Q. Pharmacological inhibitors of lysosomal degradation, such as chloroquine, increased AF1Q levels, whereas activators of CMA, including 6-aminonicotinamide and nutrient starvation, decreased AF1Q levels. AF1Q interacts with HSPA8 and LAMP-2A, which are core components of the CMA machinery. Knockdown of HSPA8 or LAMP-2A increased AF1Q protein levels, whereas overexpression showed the opposite effect. Using an amino acid deletion AF1Q mutation plasmid, we identified that AF1Q had a KFERQ-like motif which was recognized by HSPA8 for CMA-dependent proteolysis. In conclusion, we demonstrate for the first time that AF1Q can be degraded in lysosomes by CMA. - Highlights: • Chaperone-mediated autophagy (CMA) is involved in the degradation of AF1Q. • Macroautophagy does not contribute to the AF1Q degradation. • AF1Q has a KFERQ-like motif that is recognized by CMA core components.

  16. Espanol para el hispanolhablante (Spanish for the Spanish Speaker).

    ERIC Educational Resources Information Center

    Blanco, George M.

    This guide provides Texas teachers and administrators with guidelines, goals, instructional strategies, and activities for teaching Spanish to secondary level native speakers. It is based on the principle that the Spanish speaking student is the strongest linguistic and cultural resource to Texas teachers of languages other than English, and one…

  17. Topological ferrimagnetic behaviours of coordination polymers containing manganese(II) chains with mixed azide and carboxylate bridges and alternating F/AF/AF'/AF'/AF interactions.

    PubMed

    Wang, Yan-Qin; Liu, Hou-Ting; Qi, Yan; Gao, En-Qing

    2014-08-21

    Two Mn(ii) complexes with azide and a new zwitterionic tetracarboxylate ligand 1,2,4,5-tetrakis(4-carboxylatopyridinium-1-methylene)benzene (L(1)), {[Mn5(L(1))2(N3)8(OH)2]·12H2O}n () and {[Mn5(L(1))2(N3)8(H2O)2](ClO4)2·6H2O}n (), have been synthesized and characterized crystallographically and magnetically. and contain similar alternating chains constructed by azide and carboxylate bridges. The independent sets of bridges alternate in an ABCCB sequence between adjacent Mn(ii) ions: (EO-N3)2 double bridges (EO = end-on) (denoted as A), [(EO-N3)(OCO)2] triple bridges (denoted as B) and [(EO-N3)(OCO)] double bridges (denoted as C). The alternating chains are interlinked into 2D coordination networks by the tetrapyridinium spacers. Magnetic studies demonstrate that the magnetic coupling through the double EO azide bridges is ferromagnetic and that through mixed azide/carboxylate bridges is antiferromagnetic. The unprecedented F/AF/AF'/AF'/AF coupling sequence along the chain dictates an uncompensated ground spin state (S = 5/2 per Mn5 unit) and leads to one-dimensional topological ferrimagnetism, which features a minimum in the χT versus T plot.

  18. AFS Estuaries Section - A Successful Partnership

    EPA Science Inventory

    The Estuaries Section of the American Fisheries Society offers travel awards to students in support of their attendance and presentations at the AFS meeting. Since 2007, the Southern Association of Marine Laboratories has partnered with the Estuaries Section to sponsor two stude...

  19. New Mexican Spanish Verb Forms.

    ERIC Educational Resources Information Center

    Bowen, J. Donald

    This paper presents a morphophonemic analysis of the characteristics that distinguish verb structure in New Mexican Spanish from that of Standard Spanish. Verb structure and classification are discussed, and verbs are analyzed as being composed of four components: stem, thematic vowel, tense-aspect, and person-number. Verbs are classified as…

  20. Spanish for Health Care Personnel

    ERIC Educational Resources Information Center

    Palmer, Joe L.; Shawl, James R.

    1978-01-01

    Because a degree of competency in Spanish has become recognized as an essential skill for persons involved in health care activities, Northern Illinois University has developed a Spanish course tailored to the background and abilities of pre-service and in-service medical personnel. (Author/NCR)

  1. On "Tough" Movement in Spanish.

    ERIC Educational Resources Information Center

    Reider, Michael

    1993-01-01

    A survey of native Spanish speakers from both Spain and Latin America found that the choice of predicate adjectives governing "tough" constructions in Spanish (e.g., "el libro es facil de leer") varies by individual, but some patterns did emerge that suggest "tough" constructions and "it is" constructions are transformationally related. (17…

  2. The Spanish Borderlands, Historiography Redux

    ERIC Educational Resources Information Center

    Weber, David J.

    2005-01-01

    The word "borderlands" has many meanings in North American historiography, but this short overview focuses on the time and place that American historians have long known as the "Spanish Borderlands." Historian Herbert Eugene Bolton, the much-studied father of what came to be known as the "Bolton School," popularized the term "Spanish Borderlands"…

  3. Library Guide: Spanish Literature, 2001.

    ERIC Educational Resources Information Center

    de Sumar, Juanita Jara, Comp.

    Intended for use by those conducting research in Spanish literature, this guide lists selected reference materials in literature from Spain, in Spanish, Galician, and Catalan languages. Annotations in the guide are divided into the following sections: (1) General Encyclopedias (1 annotation); (2) Guides to the Literature (4 annotations); (3)…

  4. AMERICAN SOURCES OF SPANISH REALIA.

    ERIC Educational Resources Information Center

    Kansas State Teachers Coll., Emporia.

    DESIGNED FOR SPANISH TEACHERS AT ALL LEVELS, THIS BIBLIOGRAPHY OF SELECTED SPANISH REALIA CURRENTLY AVAILABLE IN THE UNITED STATES CONTAINS SECTIONS OF PICTURES, SLIDES, FLIMS, MAPS, NEWSPAPERS AND MAGAZINES, TAPES AND PHONOGRAPH RECORDS, AND PINS AND MEDALS. EACH ITEM IS ANNOTATED FOR CONTENT, COST (WHEN APPROPRIATE), NAME AND ADDRESS OF…

  5. Microfluidic Pumps Containing Teflon [Trademark] AF Diaphragms

    NASA Technical Reports Server (NTRS)

    Willis, Peter; White, Victor; Grunthaner, Frank; Ikeda, Mike; Mathies, Richard A.

    2009-01-01

    Microfluidic pumps and valves based on pneumatically actuated diaphragms made of Teflon AF polymers are being developed for incorporation into laboratory-on-a-chip devices that must perform well over temperature ranges wider than those of prior diaphragm-based microfluidic pumps and valves. Other potential applications include implanted biomedical microfluidic devices, wherein the biocompatability of Teflon AF polymers would be highly advantageous. These pumps and valves have been demonstrated to function stably after cycling through temperatures from -125 to 120 C. These pumps and valves are intended to be successors to similar prior pumps and valves containing diaphragms made of polydimethylsiloxane (PDMS) [commonly known as silicone rubber]. The PDMS-containing valves ae designed to function stably only within the temperature range from 5 to 80 C. Undesirably, PDMS membranes are somwehat porous and retain water. PDMS is especially unsuitable for use at temperatures below 0 C because the formation of ice crystals increases porosity and introduces microshear.

  6. Spanish Regulation of Biobanks.

    PubMed

    Nicolás, Pilar

    2015-01-01

    The Spanish legal framework for the processing of samples and data with biomedical research purposes has sought to encourage scientific research, protect the right to freedom of research, and guarantee the interests of donors. The pillars of this legal framework are firstly, the duty to inform the donor in order to ensure that he or she is aware of the importance and the consequences of the donation; secondly, the control by ethics committees (RECs and External Ethics Committees of biobanks); and third, the supplementary application of the general rules on data protection. There are three different possibilities for processing samples (project, collection, and biobanks) - each one reinforcing specific consent or requiring other added guarantees. This system, which is applied consistently in the entire national territory, is producing very satisfactory results. However, there are some issues that need further policies or legal development, as the specific conditions and procedures for the international transfer of samples and data with research purposes. PMID:26711419

  7. Adult Second Language Learning of Spanish Vowels

    ERIC Educational Resources Information Center

    Cobb, Katherine; Simonet, Miquel

    2015-01-01

    The present study reports on the findings of a cross-sectional acoustic study of the production of Spanish vowels by three different groups of speakers: 1) native Spanish speakers; 2) native English intermediate learners of Spanish; and 3) native English advanced learners of Spanish. In particular, we examined the production of the five Spanish…

  8. Teaching in Spanish Medical Schools.

    ERIC Educational Resources Information Center

    Bombi, Josep Antoni

    2003-01-01

    Assesses the current situation of medical teaching, available healthcare facilities, and teaching staff employed at Spanish medical schools. Response rate was 100% from 27 schools surveyed. (Author/NB)

  9. MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.

    PubMed

    Manara, Elena; Baron, Emma; Tregnago, Claudia; Aveic, Sanja; Bisio, Valeria; Bresolin, Silvia; Masetti, Riccardo; Locatelli, Franco; Basso, Giuseppe; Pigazzi, Martina

    2014-07-10

    A rare location, t(6;11)(q27;q23) (MLL-AF6), is associated with poor outcome in childhood acute myeloid leukemia (AML). The described mechanism by which MLL-AF6, through constitutive self-association and in cooperation with DOT-1L, activates aberrant gene expression does not explain the biological differences existing between t(6;11)-rearranged and other MLL-positive patients nor their different clinical outcome. Here, we show that AF6 is expressed in the cytoplasm of healthy bone marrow cells and controls rat sarcoma viral oncogene (RAS)-guanosine triphosphate (GTP) levels. By contrast, in MLL-AF6-rearranged cells, AF6 is found localized in the nucleus, leading to aberrant activation of RAS and of its downstream targets. Silencing MLL-AF6, we restored AF6 localization in the cytoplasm, thus mediating significant reduction of RAS-GTP levels and of cell clonogenic potential. The rescue of RAS-GTP levels after MLL-AF6 and AF6 co-silencing confirmed that MLL-AF6 oncoprotein potentiates the activity of the RAS pathway through retention of AF6 within the nucleus. Exposure of MLL-AF6-rearranged AML blasts to tipifarnib, a RAS inhibitor, leads to cell autophagy and apoptosis, thus supporting RAS targeting as a novel potential therapeutic strategy in patients carrying t(6;11). Altogether, these data point to a novel role of the MLL-AF6 chimera and show that its gene partner, AF6, is crucial in AML development.

  10. AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs.

    PubMed

    Tanaka, Akiko; Takano, Yuji; Ohnishi, Yasuo; Horinouchi, Sueharu

    2007-06-01

    AfsR, a protein belonging to the Streptomyces antibiotic regulatory protein (SARP) family, is a global regulator of secondary metabolism in Streptomyces coelicolor A3(2). AfsR consists of three major functional domains: an N-terminal SARP domain, a central ATPase domain, and a C-terminal tetratrico peptide repeat (TPR) domain. Two truncated AfsR proteins, AfsRDeltaTPR containing the SARP and ATPase domains and AfsRDeltaC containing only the SARP domain, exhibited the same DNA-binding specificity as that of full-length AfsR. Two monomers bound cooperatively to a direct repeat located eight nucleotides 5' to the -10 element of the afsS promoter. Both truncated AfsR proteins, as well as full-length AfsR, were able to form ternary complexes with the afsS promoter and RNA polymerase (RNAP), although RNAP alone could not bind to the DNA. The DNA-(AfsRDeltaC)(2)-RNAP complex was capable of initiating afsS transcription in vitro, indicating that the ATPase and TPR domains are dispensable for the basic function of AfsR as a transcriptional activator. However, the ATPase domain was required to fully compensate for the defect in actinorhodin production in an afsR-disrupted mutant, suggesting that the ATPase domain exerts a regulatory function on the basic SARP domain. Deletion or addition of even a single nucleotide between the AfsR-binding site and the -10 element of the afsS promoter abolished afsS transcription both in vitro and in vivo, indicating that the recruitment of RNAP by AfsR to the correct location relative to the -10 element is critical for transcriptional activation. Since SARP-binding sites with similar direct repeats are located at the same position relative to the -10 element of their target promoters as is the afsS binding site, the SARP family members presumably activate transcription of their targets by recruiting RNAP to the promoter, where a ternary DNA-SARP-RNAP complex competent for transcriptional initiation is formed.

  11. [Progress in Teflon AF LWCC/LCW applications].

    PubMed

    Sun, Zhao-Hua; Zhou, Wen; Xu, Zhan-Tang; Ye, Hai-Bin; Yang, Chao-Yu; Lin, Jun-Fang; Hu, Shui-Bo; Yang, Yue-Zhong; Li, Cai; Cao, Wen-Xi

    2011-11-01

    Teflon AF is chemically very inert, quite physically and optically stable, a highly vapor-permeable polymer with optical transparency through much of the UV-Vis region and with an RI lower than that of water, so Teflon AF LWCC/LCW (Long path-length liquid waveguide capillary cell/liquid core waveguides) has been used with a range of different detection techniques, including absorbance spectroscopy, fluorescence spectroscopy, Raman spectroscopy, and gas sensor. The present article describes the properties and the aspects of Teflon AF LWCC/LCW instrumentation and applications. And finally,the future prospect and outlook of Teflon AF LWCC/LCW is also discussed.

  12. AF4 and AF4N protein complexes: recruitment of P-TEFb kinase, their interactome and potential functions

    PubMed Central

    Scholz, Bastian; Kowarz, Eric; Rössler, Tanja; Ahmad, Khalil; Steinhilber, Dieter; Marschalek, Rolf

    2015-01-01

    AF4/AFF1 and AF5/AFF4 are the molecular backbone to assemble “super-elongation complexes” (SECs) that have two main functions: (1) control of transcriptional elongation by recruiting the positive transcription elongation factor b (P-TEFb = CyclinT1/CDK9) that is usually stored in inhibitory 7SK RNPs; (2) binding of different histone methyltransferases, like DOT1L, NSD1 and CARM1. This way, transcribed genes obtain specific histone signatures (e.g. H3K79me2/3, H3K36me2) to generate a transcriptional memory system. Here we addressed several questions: how is P-TEFb recruited into SEC, how is the AF4 interactome composed, and what is the function of the naturally occuring AF4N protein variant which exhibits only the first 360 amino acids of the AF4 full-length protein. Noteworthy, shorter protein variants are a specific feature of all AFF protein family members. Here, we demonstrate that full-length AF4 and AF4N are both catalyzing the transition of P-TEFb from 7SK RNP to their N-terminal domain. We have also mapped the protein-protein interaction network within both complexes. In addition, we have first evidence that the AF4N protein also recruits TFIIH and the tumor suppressor MEN1. This indicate that AF4N may have additional functions in transcriptional initiation and in MEN1-dependend transcriptional processes. PMID:26171280

  13. Highlights of Spanish Astrophysics III

    NASA Astrophysics Data System (ADS)

    Gallego, J.; Zamorano, J.; Cardiel, N.

    2003-09-01

    This volume documents the contributions presented at the 5th Scientific Meeting of the Spanish Astronomical Society (SEA). Covering a wide range of topics, the 154 contributed papers give a comprehensive overview of the current state of Spanish astronomy. The Proceedings include special reviews by Dr. V. Trimble and other experts dealing with the astronomical highlights of the last decade, the future of astronomical instrumentation, the scenarios of stellar evolution, the Atacama Large Millimeter Array, the intergalactic medium, the ionized interstellar medium in spiral galaxies and the substellar domain in star clusters. The contents of these proceedings thus reflect the broad interests of the Spanish astronomical community. This book is recommended to professional astronomers and astronomy graduate students worldwide.

  14. AF-MSCs fate can be regulated by culture conditions

    PubMed Central

    Zagoura, D S; Trohatou, O; Bitsika, V; Makridakis, M; Pappa, K I; Vlahou, A; Roubelakis, M G; Anagnou, N P

    2013-01-01

    Human mesenchymal stem cells (hMSCs) represent a population of multipotent adherent cells able to differentiate into many lineages. In our previous studies, we isolated and expanded fetal MSCs from second-trimester amniotic fluid (AF) and characterized them based on their phenotype, pluripotency and proteomic profile. In the present study, we investigated the plasticity of these cells based on their differentiation, dedifferentiation and transdifferentiation potential in vitro. To this end, adipocyte-like cells (AL cells) derived from AF-MSCs can regain, under certain culture conditions, a more primitive phenotype through the process of dedifferentiation. Dedifferentiated AL cells derived from AF-MSCs (DAF-MSCs), gradually lost the expression of adipogenic markers and obtained similar morphology and differentiation potential to AF-MSCs, together with regaining the pluripotency marker expression. Moreover, a comparative proteomic analysis of AF-MSCs, AL cells and DAF-MSCs revealed 31 differentially expressed proteins among the three cell populations. Proteins, such as vimentin, galectin-1 and prohibitin that have a significant role in stem cell regulatory mechanisms, were expressed in higher levels in AF-MSCs and DAF-MSCs compared with AL cells. We next investigated whether AL cells could transdifferentiate into hepatocyte-like cells (HL cells) directly or through a dedifferentiation step. AL cells were cultured in hepatogenic medium and 4 days later they obtained a phenotype similar to AF-MSCs, and were termed as transdifferentiated AF-MSCs (TRAF-MSCs). This finding, together with the increase in pluripotency marker expression, indicated the adaption of a more primitive phenotype before transdifferentiation. Additionally, we observed that AF-, DAF- and TRAF-MSCs displayed similar clonogenic potential, secretome and proteome profile. Considering the easy access to this fetal cell source, the plasticity of AF-MSCs and their potential to dedifferentiate and

  15. The Cultural Content of Business Spanish Texts.

    ERIC Educational Resources Information Center

    Grosse, Christine Uber; Uber, David

    1992-01-01

    Eight business Spanish texts were examined to learn about the cultural content of the business Spanish curriculum. Questions of cultural topics and themes, presentation of cultural information, activities and techniques, and use of authentic materials were considered. (16 references) (LB)

  16. Lengua espanola o castellana? (Spanish or Castilian?)

    ERIC Educational Resources Information Center

    Lazaro Carreter, Fernando

    1976-01-01

    This article outlines the history of the debate concerning usage of the terms "castellano" and "espanol" referring to the Spanish language. Development of the language and the question of standardization are touched on. (Text is in Spanish.) (CHK)

  17. Ecologia: Spanish Ecology Packet Resource Units and Materials for Intermediate and Advanced Spanish Classes.

    ERIC Educational Resources Information Center

    Bell, Mozelle Sawyer; Arribas, E. Jaime

    This Spanish ecology packet contains resource units and materials for intermediate and advanced Spanish classes. It is designed to be used for individual and small-group instruction in the senior high school to supplement the Spanish language curriculum. Included are articles, pictures, and cartoons from Spanish-language newspapers and magazines…

  18. Spanish Is Foreign: Heritage Speakers' Interpretations of the Introductory Spanish Language Curriculum

    ERIC Educational Resources Information Center

    DeFeo, Dayna Jean

    2015-01-01

    This article presents a case study of the perceptions of Spanish heritage speakers enrolled in introductory-level Spanish foreign language courses. Despite their own identities that were linked to the United States and Spanish of the Borderlands, the participants felt that the curriculum acknowledged the Spanish of Spain and foreign countries but…

  19. Conversational Spanish for Nursing Personnel. Level 1.

    ERIC Educational Resources Information Center

    Moffett, Oren E.

    The textbook is designed to satisfy the linguistic needs of nursing personnel who deal with monolingual Spanish speakers. The goal of the text is to enable the student to communicate in Spanish. The material stresses career-oriented "need-to-know" Spanish, relevant cultural awareness materials, practical role-playing exercises, and task…

  20. English Loanwords in Spanish Computer Language

    ERIC Educational Resources Information Center

    Cabanillas, Isabel de la Cruz; Martinez, Cristina Tejedor; Prados, Mercedes Diez; Redondo, Esperanza Cerda

    2007-01-01

    Contact with the English language, especially from the 20th century onwards, has had as a consequence an increase in the number of words that are borrowed from English into Spanish. This process is particularly noticeable in Spanish for Specific Purposes, and, more specifically, in the case of Spanish computer language. Although sociocultural and…

  1. Linguistic Perspectives from Spanish Second Language Acquisition.

    ERIC Educational Resources Information Center

    Carpenter, Mark, Ed.; Koike, Dale April, Ed.

    1998-01-01

    Papers reporting research on Spanish second language learning include: "Discourse Features of Spanish Oral Production at the Novice Level" (Rebecca Jo Bearden); "A Discourse Approach to the Assessment of Foreign Language Oral Proficiency" (Dale April Koike, Fanny Hinojosa); "Acquisition of Spanish Definite Articles by English-Speaking Learners of…

  2. Culture Curriculum for Spanish, Level 2.

    ERIC Educational Resources Information Center

    Cooper, Ina; Palumbo, Marilyn

    This curriculum guide is presented as a supplement to the text "Learning Spanish the Modern Way, Book 2" (lessons 15-23). Topics included are designed for the level-2 program by the New York State syllabus and emphasize cultural aspects of life in Spain and Mexico. The importance of Spanish, geography of Mexico and Spain, Spanish influence in the…

  3. Driving in Spanish for American Tourists.

    ERIC Educational Resources Information Center

    Grosse, Philip

    This booklet is intended to help the American tourist driving in a Spanish-speaking country to communicate with service station attendants and to understand traffic signs. The booklet consists of an alphabetical, English-Spanish glossary of terms relating to automobiles and driving and an alphabetical, Spanish-English glossary of common road…

  4. Spanish Language Health Materials: A Selective Bibliography.

    ERIC Educational Resources Information Center

    Trujillo, Roberto G., Ed.; And Others

    This selected bibliography, compiled from recommendations by practicing librarians providing service to Spanish-speaking communities, includes Spanish and bilingual Spanish/English materials dealing with health. The topic is broadly defined to include any conditions which affect a person's well-being, and includes alcohol and drugs, consumer…

  5. CINDOC, CSIC, and Spanish R and D

    NASA Technical Reports Server (NTRS)

    Delaviesca, Rosa

    1994-01-01

    The organizational structure and functional activities of the Spanish Center for Scientific Information and Documentation (CINDOC) are discussed. The library holds 8,500 journals, including all the Spanish scientific journals; 16,000 books and 20 CD-ROM data bases. CINDOC creates and distributes its own data bases that include all the articles published in Spanish scientific journals.

  6. Spanish Guide. Kindergarten. Michigan Oral Language Series.

    ERIC Educational Resources Information Center

    Soriano, Jesse M.; And Others

    This guide, designed for use by kindergarten teachers, to teach Spanish to speakers of other languages and to teach standard Spanish to speakers of non-standard Spanish, contains 136 half hour lessons, covering the school year. The completely oral program presents a structured sequence of language learning experiences geared to the children's…

  7. 7 CFR Exhibits A-F to Subpart A... - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 14 2013-01-01 2013-01-01 false A Exhibits A-F to Subpart A of Part 1955 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... Real and Chattel Property Exhibits A-F to Subpart A of Part 1955...

  8. 7 CFR Exhibits A-F to Subpart A... - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false A Exhibits A-F to Subpart A of Part 1955 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... Real and Chattel Property Exhibits A-F to Subpart A of Part 1955...

  9. 7 CFR Exhibits A-F to Subpart A... - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 14 2011-01-01 2011-01-01 false A Exhibits A-F to Subpart A of Part 1955 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... Real and Chattel Property Exhibits A-F to Subpart A of Part 1955...

  10. 7 CFR Exhibits A-F to Subpart A... - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false A Exhibits A-F to Subpart A of Part 1955 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... Real and Chattel Property Exhibits A-F to Subpart A of Part 1955...

  11. 7 CFR Exhibits A-F to Subpart A... - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true A Exhibits A-F to Subpart A of Part 1955 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... Real and Chattel Property Exhibits A-F to Subpart A of Part 1955...

  12. Part III: AFS - A Secure Distributed File System

    SciTech Connect

    Wachsmann, A.; /SLAC

    2005-06-29

    AFS is a secure distributed global file system providing location independence, scalability and transparent migration capabilities for data. AFS works across a multitude of Unix and non-Unix operating systems and is used at many large sites in production for many years. AFS still provides unique features that are not available with other distributed file systems even though AFS is almost 20 years old. This age might make it less appealing to some but with IBM making AFS available as open-source in 2000, new interest in use and development was sparked. When talking about AFS, people often mention other file systems as potential alternatives. Coda (http://www.coda.cs.cmu.edu/) with its disconnected mode will always be a research project and never have production quality. Intermezzo (http://www.inter-mezzo.org/) is now in the Linux kernel but not available for any other operating systems. NFSv4 (http://www.nfsv4.org/) which picked up many ideas from AFS and Coda is not mature enough yet to be used in serious production mode. This article presents the rich features of AFS and invites readers to play with it.

  13. Embedding Assessment for Learning (AfL) into Science

    ERIC Educational Resources Information Center

    Crossland, John

    2012-01-01

    Although the National Strategies for improving English schools no longer exist, the "Pedagogy and Practice" pack provides a valuable resource for producing an Assessment for Learning (AfL) framework that describes a hierarchy of skills for AfL. Based on the hierarchy, training took place in three North Yorkshire schools. To focus attention on the…

  14. DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex

    PubMed Central

    Mück, Fabian; Bracharz, Silvia; Marschalek, Rolf

    2016-01-01

    AF4/AFF1 and AF5/AFF4 are both backbones for the assembly of “super elongation complexes” (SECs) that exert 2 distinct functions after the recruitment of P-TEFb from the 7SK snRNP: (1) initiation and elongation of RNA polymerase II gene transcription, and (2) modification of transcribed gene regions by distinct histone methylation patterns. In this study we aimed to investigate one of the initial steps, namely how P-TEFb is transferred from 7SK snRNPs to the SECs. In particular, we were interested in the role of DDX6 that we have recently identified as part of the AF4 complex. DDX6 is an evolutionarily conserved member of the DEAD-box RNA helicase family that is known to control miRNA and mRNA biology (translation, storage and degradation). Overexpressed DDX6 is associated with different cancer types and with c-Myc protein overexpression. We could demonstrate that DDX6 binds to 7SK snRNA and causes the release and transfer of P-TEFb to the AF4/AF4N SEC. DDX6 also binds stably to AF4 and AF4N as demonstrated by GST pull-down and co-immunoprecipitation experiments. As a consequence, overexpression of either AF4/AF4N or DDX6 resulted in a strong increase of mRNA production (5-6 fold), while their simultaneous expression increased the cellular mRNA production by 11-fold. Conversely, the corresponding knockdown of DDX6 decreased mRNA production by 70%. In conclusion, AF4/AF4N and DDX6 represent key molecules for the elongation process of gene transcription and a model will be proposed for the hand-over process of P-TEFb to SECs. PMID:27679741

  15. DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex.

    PubMed

    Mück, Fabian; Bracharz, Silvia; Marschalek, Rolf

    2016-01-01

    AF4/AFF1 and AF5/AFF4 are both backbones for the assembly of "super elongation complexes" (SECs) that exert 2 distinct functions after the recruitment of P-TEFb from the 7SK snRNP: (1) initiation and elongation of RNA polymerase II gene transcription, and (2) modification of transcribed gene regions by distinct histone methylation patterns. In this study we aimed to investigate one of the initial steps, namely how P-TEFb is transferred from 7SK snRNPs to the SECs. In particular, we were interested in the role of DDX6 that we have recently identified as part of the AF4 complex. DDX6 is an evolutionarily conserved member of the DEAD-box RNA helicase family that is known to control miRNA and mRNA biology (translation, storage and degradation). Overexpressed DDX6 is associated with different cancer types and with c-Myc protein overexpression. We could demonstrate that DDX6 binds to 7SK snRNA and causes the release and transfer of P-TEFb to the AF4/AF4N SEC. DDX6 also binds stably to AF4 and AF4N as demonstrated by GST pull-down and co-immunoprecipitation experiments. As a consequence, overexpression of either AF4/AF4N or DDX6 resulted in a strong increase of mRNA production (5-6 fold), while their simultaneous expression increased the cellular mRNA production by 11-fold. Conversely, the corresponding knockdown of DDX6 decreased mRNA production by 70%. In conclusion, AF4/AF4N and DDX6 represent key molecules for the elongation process of gene transcription and a model will be proposed for the hand-over process of P-TEFb to SECs. PMID:27679741

  16. DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex

    PubMed Central

    Mück, Fabian; Bracharz, Silvia; Marschalek, Rolf

    2016-01-01

    AF4/AFF1 and AF5/AFF4 are both backbones for the assembly of “super elongation complexes” (SECs) that exert 2 distinct functions after the recruitment of P-TEFb from the 7SK snRNP: (1) initiation and elongation of RNA polymerase II gene transcription, and (2) modification of transcribed gene regions by distinct histone methylation patterns. In this study we aimed to investigate one of the initial steps, namely how P-TEFb is transferred from 7SK snRNPs to the SECs. In particular, we were interested in the role of DDX6 that we have recently identified as part of the AF4 complex. DDX6 is an evolutionarily conserved member of the DEAD-box RNA helicase family that is known to control miRNA and mRNA biology (translation, storage and degradation). Overexpressed DDX6 is associated with different cancer types and with c-Myc protein overexpression. We could demonstrate that DDX6 binds to 7SK snRNA and causes the release and transfer of P-TEFb to the AF4/AF4N SEC. DDX6 also binds stably to AF4 and AF4N as demonstrated by GST pull-down and co-immunoprecipitation experiments. As a consequence, overexpression of either AF4/AF4N or DDX6 resulted in a strong increase of mRNA production (5-6 fold), while their simultaneous expression increased the cellular mRNA production by 11-fold. Conversely, the corresponding knockdown of DDX6 decreased mRNA production by 70%. In conclusion, AF4/AF4N and DDX6 represent key molecules for the elongation process of gene transcription and a model will be proposed for the hand-over process of P-TEFb to SECs.

  17. Toward a petabyte-scale AFS service at CERN

    NASA Astrophysics Data System (ADS)

    van der Ster, Daniel; Moscicki, Jakub T.; Wiebalck, Arne

    2014-06-01

    AFS is a mature and reliable storage service at CERN, having worked for more than 20 years as the provider of Unix home directories and project areas. Recently, the AFS service has grown at unprecedented rates (200% in the past year); this growth was unlocked thanks to innovations in both the hardware and software components of our file servers. This work presents how AFS is used at CERN and how the service offering is evolving with the increasing storage needs of its local and remote user communities. In particular, we demonstrate the usage patterns for home directories, workspaces and project spaces, as well as show the daily work which is required to rebalance data and maintaining stability and performance. Finally, we highlight some recent changes and optimisations made to the AFS Service, thereby revealing how AFS can possibly operate at all while being subjected to frequent-almost DDOS-like-attacks from its users.

  18. Teaching Sociocultural Literacy. Spanish Fiesta.

    ERIC Educational Resources Information Center

    Kenwood, Alun

    1998-01-01

    Describes the rich, historical tradition of festivals in Spain, explaining that a multidisciplinary focus is necessary to understand the full significance of fiesta in Spain (geography, history, music, literature, and the fine arts). Students should be encouraged to study Spanish fiestas in order to develop a deep understanding of the diversity of…

  19. Spanish Language Workbook (In Development).

    ERIC Educational Resources Information Center

    Peace Corps, Santiago (Chile).

    This guide is designed for the Spanish language training of Peace Corps workers in Chile and reflects daily communication needs in that context. The workbook contains a series of sentence completion exercises at the intermediate to advanced level, notes and exercises on metric system conversion, verb/substantive lists, specialized vocabulary lists…

  20. The Spanish-Language Roundtable.

    ERIC Educational Resources Information Center

    Criticas: An English Speaker's Guide to the Latest Spanish Language Titles, 2003

    2003-01-01

    Reports on a meeting with a group of experts including Leylha Ahuile, Rene Alegria, Rueben Martinez, Diana Martinez Calice, Silvia Matute, Anne Messitte, and Teresa Mlawer from the Spanish language market for books. Topics include publishing; school and library markets; bookstores; the role of the Latino press and Latino authors; coverage in…

  1. Spanglish: An Anglicized Spanish Dialect

    ERIC Educational Resources Information Center

    Ardila, Alfredo

    2005-01-01

    The blend between Spanish and English found in Hispanic or Latino communities in the United States is usually known as "Spanglish." It is suggested that Spanglish represents the most important contemporary linguistic phenomenon in the United States that has barely been approached from a linguistic point of view. Spanglish may be interpreted in…

  2. Spanish Aid in Clinical Dietetics.

    ERIC Educational Resources Information Center

    Bringas, Juliet G.; Chan, Teresa Y.

    Designed to aid dietitians, nutritionists, and other health professionals to better serve the nutritional needs of Hispanics, this bilingual booklet describes the different cultural eating habits of Mexican, Cuban, and Puerto Rican Americans, with in-depth description of Mexican Americans. Written in Spanish and English, the booklet includes…

  3. Teaching Spanish for Technical Purposes.

    ERIC Educational Resources Information Center

    Cline, William

    An Eastern Michigan University course in Spanish for special purposes with an emphasis on technology was intended to serve students of business, international trade, and technology, but the actual enrollment came largely from the department of foreign languages and bilingual studies. However, significant diversity in scientific preparation and…

  4. Guidance Services in Spanish Universities

    ERIC Educational Resources Information Center

    Vidal, Javier; Diez, Gloria; Vieira, Maria J.

    2003-01-01

    Since the 80s, higher education in Spain has undergone important modifications such as greater autonomy, expansion in the number of students and the introduction of more flexible programmes. In this context, guidance services have proliferated in an unstructured way. This paper presents a description of guidance services in Spanish universities…

  5. Medical Spanish: A Functional Approach.

    ERIC Educational Resources Information Center

    Hendrickson, James M.

    A functional approach to language teaching begins with knowing how students intend to use the foreign language for specific purposes and in specific situations. Instructors of medical Spanish can begin by determining the specific language functions that their students must be able to express when communicating with Hispanic patients, by means of a…

  6. An Implicit LU/AF FDTD Method

    NASA Technical Reports Server (NTRS)

    Beggs, John H.; Briley, W. Roger

    2001-01-01

    There has been some recent work to develop two and three-dimensional alternating direction implicit (ADI) FDTD schemes. These ADI schemes are based upon the original ADI concept developed by Peaceman and Rachford and Douglas and Gunn, which is a popular solution method in Computational Fluid Dynamics (CFD). These ADI schemes work well and they require solution of a tridiagonal system of equations. A new approach proposed in this paper applies a LU/AF approximate factorization technique from CFD to Maxwell s equations in flux conservative form for one space dimension. The result is a scheme that will retain its unconditional stability in three space dimensions, but does not require the solution of tridiagonal systems. The theory for this new algorithm is outlined in a one-dimensional context for clarity. An extension to two and threedimensional cases is discussed. Results of Fourier analysis are discussed for both stability and dispersion/damping properties of the algorithm. Results are presented for a one-dimensional model problem, and the explicit FDTD algorithm is chosen as a convenient reference for comparison.

  7. Highlights of Spanish Astrophysics VII

    NASA Astrophysics Data System (ADS)

    Guirado, J. C.; Lara, L. M.; Quilis, V.; Gorgas, J.

    2013-05-01

    "Highlights of Astronomy and Astrophysics VII" contains the Proceedings of the biannual meeting of the Spanish Astronomical Society held in Valencia from July 9 to 13, 2012. Over 300 astronomer, both national and international researchers, attended to the conference covering a wide variety of astrophysical topics: Galaxies and Cosmology, The Milky Way and Its Components, Planetary Sciences, Solar Physics, Instrumentation and Computation, and Teaching and Outreach of Astronomy.

  8. SPANISH PEAKS PRIMITIVE AREA, MONTANA.

    USGS Publications Warehouse

    Calkins, James A.; Pattee, Eldon C.

    1984-01-01

    A mineral survey of the Spanish Peaks Primitive Area, Montana, disclosed a small low-grade deposit of demonstrated chromite and asbestos resources. The chances for discovery of additional chrome resources are uncertain and the area has little promise for the occurrence of other mineral or energy resources. A reevaluation, sampling at depth, and testing for possible extensions of the Table Mountain asbestos and chromium deposit should be undertaken in the light of recent interpretations regarding its geologic setting.

  9. Tuning the Music: Acoustic Force Spectroscopy (AFS) 2.0.

    PubMed

    Kamsma, Douwe; Creyghton, Ramon; Sitters, Gerrit; Wuite, Gijs J L; Peterman, Erwin J G

    2016-08-01

    AFS is a recently introduced high-throughput single-molecule technique that allows studying structural and mechanochemical properties of many biomolecules in parallel. To further improve the method, we developed a modelling tool to optimize the layer thicknesses, and a calibration method to experimentally validate the modelled force profiles. After optimization, we are able to apply 350pN on 4.5μm polystyrene beads, without the use of an amplifier, at the coverslip side of the AFS chip. Furthermore, we present the use of a transparent piezo to generate the acoustic force and we show that AFS can be combined with high-NA oil or water-immersion objectives. With this set of developments AFS will be applicable to a broad range of single-molecule experiments. PMID:27163865

  10. 7 CFR 51.2731 - U.S. Spanish Splits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Spanish Splits. 51.2731 Section 51.2731... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2731 U.S. Spanish Splits. “U.S. Spanish Splits” consists of shelled Spanish type peanut kernels which are split or...

  11. Keeping Pace: Science Trade Books in Spanish.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1985-01-01

    Describes elementary school science trade books written in Spanish. Topics considered in these books include: animal life; astronomy; biology; earth sciences; mathematics; general science; and general technology. (DH)

  12. Complex Transcriptional Control of the Antibiotic Regulator afsS in Streptomyces: PhoP and AfsR Are Overlapping, Competitive Activators▿

    PubMed Central

    Santos-Beneit, Fernando; Rodríguez-García, Antonio; Martín, Juan F.

    2011-01-01

    The afsS gene of several Streptomyces species encodes a small sigma factor-like protein that acts as an activator of several pathway-specific regulatory genes (e.g., actII-ORF4 and redD in Streptomyces coelicolor). The two pleiotropic regulators AfsR and PhoP bind to overlapping sequences in the −35 region of the afsS promoter and control its expression. Using mutated afsS promoters containing specific point mutations in the AfsR and PhoP binding sequences, we proved that the overlapping recognition sequences for AfsR and PhoP are displaced by 1 nucleotide. Different nucleotide positions are important for binding of AfsR or PhoP, as shown by electrophoretic mobility shift assays and by reporter studies using the luxAB gene coupled to the different promoters. Mutant promoter M5 (with a nucleotide change at position 5 of the consensus box) binds AfsR but not PhoP with high affinity (named “superAfsR”). Expression of the afsS gene from this promoter led to overproduction of actinorhodin. Mutant promoter M16 binds PhoP with extremely high affinity (“superPhoP”). Studies with ΔafsR and ΔphoP mutants (lacking AfsR and PhoP, respectively) showed that both global regulators are competitive transcriptional activators of afsS. AfsR has greater influence on expression of afsS than PhoP, as shown by reverse transcriptase PCR (RT-PCR) and promoter reporter (luciferase) studies. These two high-level regulators appear to integrate different nutritional signals (particularly phosphate limitation sensed by PhoR), S-adenosylmethionine, and other still unknown environmental signals (leading to AfsR phosphorylation) for the AfsS-mediated control of biosynthesis of secondary metabolites. PMID:21378195

  13. Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators.

    PubMed

    Santos-Beneit, Fernando; Rodríguez-García, Antonio; Martín, Juan F

    2011-05-01

    The afsS gene of several Streptomyces species encodes a small sigma factor-like protein that acts as an activator of several pathway-specific regulatory genes (e.g., actII-ORF4 and redD in Streptomyces coelicolor). The two pleiotropic regulators AfsR and PhoP bind to overlapping sequences in the -35 region of the afsS promoter and control its expression. Using mutated afsS promoters containing specific point mutations in the AfsR and PhoP binding sequences, we proved that the overlapping recognition sequences for AfsR and PhoP are displaced by 1 nucleotide. Different nucleotide positions are important for binding of AfsR or PhoP, as shown by electrophoretic mobility shift assays and by reporter studies using the luxAB gene coupled to the different promoters. Mutant promoter M5 (with a nucleotide change at position 5 of the consensus box) binds AfsR but not PhoP with high affinity (named "superAfsR"). Expression of the afsS gene from this promoter led to overproduction of actinorhodin. Mutant promoter M16 binds PhoP with extremely high affinity ("superPhoP"). Studies with ΔafsR and ΔphoP mutants (lacking AfsR and PhoP, respectively) showed that both global regulators are competitive transcriptional activators of afsS. AfsR has greater influence on expression of afsS than PhoP, as shown by reverse transcriptase PCR (RT-PCR) and promoter reporter (luciferase) studies. These two high-level regulators appear to integrate different nutritional signals (particularly phosphate limitation sensed by PhoR), S-adenosylmethionine, and other still unknown environmental signals (leading to AfsR phosphorylation) for the AfsS-mediated control of biosynthesis of secondary metabolites.

  14. The Dimensionality of Spanish in Young Spanish-English Dual-Language Learners

    ERIC Educational Resources Information Center

    Journal of Speech, Language, and Hearing Research, 2015

    2015-01-01

    Purpose: This study examined the latent dimensionality of Spanish in young Spanish-English dual-language learners (DLLs). Method: Two hundred eighty-six children participated. In their prekindergarten year, children completed norm-referenced and experimental language measures in Spanish requiring different levels of cognitive processing in both…

  15. High School Spanish Teachers' Attitudes and Practices toward Spanish Heritage Language Learners

    ERIC Educational Resources Information Center

    Russell, Brittany D.; Kuriscak, Lisa M.

    2015-01-01

    This case study uses survey data to examine the attitudes and pedagogical practices of preservice and current high school Spanish teachers toward Spanish heritage language learners (HLLs). The research questions addressed were (1) the extent to which participants were aware of the challenges facing Spanish HLLs who are enrolled in traditional…

  16. An Investigation of Anglicized Spanish as a Communication Strategy in the Beginning Spanish Classroom

    ERIC Educational Resources Information Center

    Kobeck, Ashley Brianne

    2013-01-01

    Considering the recent increase in Spanish use in the United States, particularly as reflected in the media, beginning Spanish students are entering their classrooms with knowledge of phrases such as "hasta la vista" and "numero uno," regardless of their amount of previous formal Spanish study. The present research focuses on…

  17. A Spanish perspective on LD.

    PubMed

    González, J E; Valle, I H

    1999-01-01

    This article offers an overview of special education in Spain, specifically in the area of learning disabilities (LD). The term LD in Spain implies a different conception of the definition that enjoys considerable international agreement and consensus. We give a historical perspective of Spanish legislation and place the proposed definition of LD in the context of recent school reform in Spain. The support services model and the assessment practices and instructional approaches in the LD field are described. Finally, some educational implications of the new school reform regarding teacher training programs to assist special educational needs are presented. PMID:15508246

  18. Commercial Spanish: Developing Proficiencies and Business Practices.

    ERIC Educational Resources Information Center

    Reyes-Tudela, Jose E.

    A commercial Spanish course offered at Marywood College (Scranton, Pennsylvania) serves both Spanish majors and majors in international business. In addition to language proficiency activities common to most commercial language courses, students have identified two projects as most functional and challenging: (1) a "carpeta" or file into which…

  19. The Spanish Family Guidance Center of Miami.

    ERIC Educational Resources Information Center

    Hispanic Research Center: Research Bulletin, 1979

    1979-01-01

    Two major programs of the Spanish Family Guidance Center, a facility that addresses the mental health needs of Hispanics in the Greater Miami (Florida) area, are described in this report. One program, the Spanish Drug Rehabilitation Project (completed in 1977), compared a series of activities including: (1) research on the characteristics of…

  20. Commercial Communication in the Spanish Language.

    ERIC Educational Resources Information Center

    Reinhardt-Childers, Ilva

    A college course in commercial Spanish is described. The course objectives are to: build a solid foundation of business and professional vocabulary, grammar, spelling, and punctuation; prepare for oral and written communication with commonly-used Spanish business phrases and terminology; expose students to the different types of written…

  1. A Marketing Strategy for Spanish for Business.

    ERIC Educational Resources Information Center

    Grosse, Christine Uber

    The development of a marketing strategy for business Spanish courses by means of situational analysis is described. The planner of marketing strategy must consider demand for a course, institutional acceptance, and financial support. A survey of 508 universities revealed a low level of demand for business Spanish which could potentially be…

  2. Chicago's Spanish-Speaking Population: Selected Statistics.

    ERIC Educational Resources Information Center

    Chicago Dept. of Development and Planning, IL.

    Based on selected data from the 1970 census, this report provides a general description of Chicago's Spanish-speaking population's: (1) general population characteristics; (2) age and family characteristics; (3) income; (4) labor force characteristics; (5) education; and (6) housing. Using the Census Bureau's definition of Spanish speaking (all…

  3. Development of Spanish Consonants in Preschool Children.

    ERIC Educational Resources Information Center

    Acevedo, Mary Ann

    1993-01-01

    This study tested the production of 18 Spanish consonants by 120 Mexican-American preschool children (ages 3-5), to determine the age of acquisition of Spanish consonants. Data are provided on percent of correct production of each sound at six different age levels and are graphically illustrated to compare age of acquisition with another study's…

  4. The Suffix "-oso" in Central American Spanish.

    ERIC Educational Resources Information Center

    Scavnicky, Gary Eugene A.

    1982-01-01

    Examines the lexical formative "-oso," which is added to nominal and verbal roots to form adjectives to denote possession of the quality contained in the primitive, in Central American Spanish. Concludes it is used with traditional Spanish denotations and has undergone various semantic shifts and is being applied to roots in a completely…

  5. Variation in Miami Cuban Spanish Interrogative Intonation

    ERIC Educational Resources Information Center

    Alvord, Scott M.

    2010-01-01

    The interrogative intonation of Cubans and Cuban Americans living in Miami is investigated. Two different intonation patterns are used in this variety of Spanish to convey absolute interrogative meaning: one with a falling final contour, as has been observed in Cuban Spanish, and one with a rising final contour, as is used in American English and…

  6. Black/Indian Interaction in Spanish Florida.

    ERIC Educational Resources Information Center

    Landers, Jane

    The history of the lives of non-white peoples in the United States largely has been neglected although the Spanish bureaucrats kept meticulous records of the Spanish Mission period in Florida. These records represent an important source for the cultural history of these groups and offer new perspectives on the tri-racial nature of frontier…

  7. Forms of Address in Chilean Spanish

    ERIC Educational Resources Information Center

    Bishop, Kelley; Michnowicz, Jim

    2010-01-01

    The present investigation examines possible social and linguistic factors that influence forms of address used in Chilean Spanish with various interlocutors. A characteristic of the Spanish of Chile is the use of a variety of forms of address for the second person singular, "tu", "vos", and "usted", with corresponding verb conjugations (Lipski…

  8. "Plaza Sesamo" and Spanish Language Learning.

    ERIC Educational Resources Information Center

    Pearson, Sulamita R.

    The Spanish version of "Sesame Street" was used in a project in a class of 12 students in the second semester of first-year Spanish at Phillips Exeter Academy, and an attempt was made to evaluate the usefulness of the series in second language acquisition. This account of the project has five parts: (1) a history of the production of "Plaza…

  9. Noteworthy Books in Spanish for Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1993-01-01

    This annotated bibliography lists 28 books in Spanish recommended for adolescents and published in 1990-92. Categories include biography, fiction, health, history, poetry, and science. The work of the Center of the Study of Books in Spanish for Children and Adolescents, at the California State University, San Marcos, is also described. (MSE)

  10. Noteworthy Books in Spanish for Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2002-01-01

    This annotated bibliography includes 18 titles that appeal to Spanish-speaking teens under the categories of contemporary novels, historical fiction, longtime favorites, health, and myths and legends. A sidebar lists dealers of books in Spanish for children and young adults. (LRW)

  11. Selecting Books in Spanish To Teach Mathematics.

    ERIC Educational Resources Information Center

    Jacobs, Victoria R.; Bennett, Tom R.; Bullock, Cathy

    2000-01-01

    Introduces a resource for identifying and obtaining high-quality children's literature printed in Spanish and published worldwide. Presents some guidelines for selecting literature to teach mathematics. Provides specific examples of Spanish language books that are high-quality and have strong potential for furthering students' mathematical…

  12. Noteworthy Books in Spanish for Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2000-01-01

    Spanish-speaking adolescents' interests and tastes in books vary as much as those of their English-speaking counterparts. This annotated bibliography includes brief short stories, realistic novels, an Internet guide, engrossing mysteries, passionate poems, all recently published books available for Spanish-speaking adolescents. (AEF)

  13. Career Spanish at Mesa State College.

    ERIC Educational Resources Information Center

    Pilkenton, David

    The development and results of Career Spanish instruction at Mesa State College in Colorado from 1975 to 1991 are described. The class is an individualized, career-oriented class for students who have only 3 to 6 semester hours available for foreign language study and an interest in particular vocational applications of Spanish. With no…

  14. Modeling Spanish Mood Choice in Belief Statements

    ERIC Educational Resources Information Center

    Robinson, Jason R.

    2013-01-01

    This work develops a computational methodology new to linguistics that empirically evaluates competing linguistic theories on Spanish verbal mood choice through the use of computational techniques to learn mood and other hidden linguistic features from Spanish belief statements found in corpora. The machine learned probabilistic linguistic models…

  15. "Proyecto Sherezade": Teaching Spanish Literature Interactively.

    ERIC Educational Resources Information Center

    Fernandez, Enrique

    2001-01-01

    Describes "Proyecto Sherezade," an Internet-based project publicly available to anyone. Founded in 1996 by a group of Spanish language and literature academics in Canada and the United States, the project began as an Internet literary magazine that published non-established writers's short stories in Spanish and commentaries sent by readers.…

  16. Black Frontier Settlements in Spanish Colonial Florida.

    ERIC Educational Resources Information Center

    Landers, Jane

    1988-01-01

    Addresses the much neglected area of Black frontier experience in the Spanish colonies. Concentrates on the role played by Black settlers and one Black township in defending the Spanish frontier in colonial Florida against the threat of growing English settlements to the north. Provides an introduction to the 18th century Southeastern Spanish…

  17. Language Transference by Mentally Retarded Spanish Speakers.

    ERIC Educational Resources Information Center

    Flaherty, Carol

    In an investigation of language transference vs. language interference, 12 trainable mentally retarded Spanish speakers (5 to 9 years old) were trained to name in English objects previously identified receptively and objects not previously identified receptively in Spanish. Results indicated no significant difference in the number of words learned…

  18. Defying Analysis: Spanish-American Plural Formation.

    ERIC Educational Resources Information Center

    Romens, Thomas L.

    Spanish American plural formation is discussed in relation to attempts that have been made to write a set of phonological rules that would correctly predict the Spanish plural using a combination of phonological rules and word structure constraints. A brief synopsis is resented of why previous attempts to predict the plural are in error.…

  19. Workplace Spanish for Health Care Workers.

    ERIC Educational Resources Information Center

    Garcia, Paula

    This syllabus and curriculum guide were developed for a 12-week course in workplace Spanish for clinical workers at the Claretian Medical Center on the south side of Chicago. The purpose of the class was to provide basic communicative abilities in Spanish to the medical staff---registered nurses, triage nurses, and laboratory technologists--such…

  20. How To Learn Spanish the Easy Way.

    ERIC Educational Resources Information Center

    Kampe, Livia

    An approach to learning Spanish is presented in this guide that builds on the similarities of alphabet, structure, and vocabulary between Spanish and English. The first two introductory lessons deal with the similarities and differences of the alphabet and sentence structure, and the third covers important words to memorize, including…

  1. Bibliografia en Espanol (Bibliography in Spanish).

    ERIC Educational Resources Information Center

    San Diego County Office of Education, CA.

    Teachers, librarians and resource teachers are provided with a list of 110 high quality books in the Spanish language which will help the needs of limited and non-English-speaking students. The entries are annotated in English and graded "Primary,""Intermediate," and/or "Junior High." Four of the stories are classified as Spanish/English. The…

  2. Spanish for Agricultural Purposes: The Video Episodes.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.; And Others

    The transcripts of dialogues from videotape recordings were developed, along with accompanying language laboratory material, as part of a one-semester course in Spanish for North American agriculture specialists preparing to work in Latin America. Included are 48 episodes covering such topics as: working with a local Spanish-speaking counterpart,…

  3. THE SPANISH AMERICANS IN NEW MEXICO.

    ERIC Educational Resources Information Center

    KNOWLTON, CLARK S.

    THE SPANISH AMERICANS IN NEW MEXICO ARE UNDERGOING GREAT SOCIAL AND CULTURAL CHANGE. THEIR VILLAGE CULTURE, FORMED IN ISOLATION NEAR IRRIGATED LAND WHICH HAD REMAINED REMARKABLY STABLE FOR SEVERAL HUNDRED YEARS, IS BREAKING DOWN. THE SPANISH AMERICANS ARE LEAVING THEIR VILLAGES AND MIGRATING TO INDUSTRIAL CENTERS. FACTORS CONTRIBUTING TO THIS…

  4. Effects of iron depletion on CALM-AF10 leukemias.

    PubMed

    Heath, Jessica L; Weiss, Joshua M; Lavau, Catherine P; Wechsler, Daniel S

    2014-12-01

    Iron, an essential nutrient for cellular growth and proliferation, enters cells via clathrin-mediated endocytosis. The clathrin assembly lymphoid myeloid (CALM) protein plays an essential role in the cellular import of iron by clathrin-mediated endocytosis. CALM-AF10 leukemias harbor a single copy of the normal CALM gene and therefore may be more sensitive to the growth-inhibitory effect of iron restriction compared with normal hematopoietic cells. We found that CALM heterozygous (CALM(HET)) murine fibroblasts exhibit signs of iron deficiency, with increased surface transferrin receptor levels and reduced growth rates. CALM(HET) hematopoietic cells are more sensitive in vitro to iron chelators than their wild type counterparts. Iron chelation also displayed toxicity toward cultured CALM(HET)CALM-AF10 leukemia cells, and this effect was additive to that of chemotherapy. In mice transplanted with CALM(HET)CALM-AF10 leukemia, we found that dietary iron restriction reduced tumor burden in the spleen. However, dietary iron restriction, used alone or in conjunction with chemotherapy, did not increase survival of mice with CALM(HET)CALM-AF10 leukemia. In summary, although CALM heterozygosity results in iron deficiency and increased sensitivity to iron chelation in vitro, our data in mice do not suggest that iron depletion strategies would be beneficial for the therapy of CALM-AF10 leukemia patients.

  5. The German-Spanish connection

    NASA Astrophysics Data System (ADS)

    Robinson, L. J.

    1980-04-01

    Cooperation between West Germany and Spain in the field of observational astronomy is discussed, with particular attention given to the newly operational German-Spanish Astronomical Center atop Calar Alto, Spain. The history of German and Spanish observational astronomy is briefly indicated as motivation for the joint venture, and the construction of the Calar Alto observatory, a branch of the Max Planck Institute for Astronomy, is outlined. The Center's instruments consist of the operational 1.2-m reflector employing an aplanatic Ritchey-Chretien system and a two-element field corrector, the 2.2-m reflector again with a Ritchey-Chretien optical system with field corrector however using a four-mirror coude arrangement, and a 3.5-m reflector under construction. Current objects of research include the bipolar H II region S 106, and extragalactic objects such as BL Lac objects, quasars and active galaxies. Organizational and operational aspects of the Center and the Max Planck Institute for Astronomy are also outlined.

  6. Comprehending Conceptual Anaphors in Spanish

    PubMed Central

    Carreiras, Manuel; Gernsbacher, Morton Ann

    2014-01-01

    This paper examines the mechanisms involved in the assignment of an antecedent to an anaphoric element. In general, pronouns must match their antecedents at least with respect to number and gender. Sensitivity to such constraints has been shown in several experiments. But Gernsbacher (1991) has also shown that people have no difficulty comprehending a plural pronoun with an antecedent that is grammatically singular but conceptually plural. In the first three experiments, we tested whether such a “conceptual effect” was preserved with zero anaphors in Spanish. (The typical omission of pronouns in subject position in Spanish.) Verbs in a second clause were marked with plural or singular endings. Plural verbs were rated more natural than singular verbs when they followed three types of singular but conceptually plural antecedents (Experiment 1). Clauses containing plural verbs were read faster when they followed one type of singular but conceptually plural antecedents, i.e. collective sets (Experiments 2 and 3). In fact, clauses containing plural verbs were read equally fast when they followed literally singular collective sets or explicitly group nouns. Using pronominal anaphors, these reading time effects were replicated and extended to sentences that contained generic types as antecedents (Experiment 4). The results are discussed in terms of the use of information during the comprehension of anaphors. PMID:25425750

  7. GPIM AF-M315E Propulsion System

    NASA Technical Reports Server (NTRS)

    Spores, Ronald A.; Masse, Robert; Kimbrel, Scott; McLean, Chris

    2014-01-01

    The NASA Space Technology mission Directorate's (STMD) Green Propellant Infusion Mission (GPIM) Technology Demonstration Mission (TDM) will demonstrate an operational AF-M315E green propellant propulsion system. Aerojet-Rocketdyne is responsible for the development of the propulsion system payload. This paper statuses the propulsion system module development, including thruster design and system design; Initial test results for the 1N engineering model thruster are presented. The culmination of this program will be high-performance, green AF-M315E propulsion system technology at TRL 7+, with components demonstrated to TRL 9, ready for direct infusion to a wide range of applications for the space user community.

  8. afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2).

    PubMed

    Lee, Ping-Chin; Umeyama, Takashi; Horinouchi, Sueharu

    2002-03-01

    AfsR is a pleiotropic, global regulator that controls the production of actinorhodin, undecylprodigiosin and calcium-dependent antibiotic in Streptomyces coelicolor A3(2). AfsR, with 993 amino acids, is phosphorylated on serine and threonine residues by a protein serine/threonine kinase AfsK and contains an OmpR-like DNA-binding fold at its N-terminal portion and A- and B-type nucleotide-binding motifs in the middle of the protein. The DNA-binding domain, in-dependently of the nucleotide-binding domain, contributed the binding of AfsR to the upstream region of afsS that locates immediately 3' to afsR and encodes a 63-amino-acid protein. No transcription of afsS in the DeltaafsR background and restoration of afsS transcription by afsR on a plasmid in the same genetic background indicated that afsR served as a transcriptional activator for afsS. Interestingly, the AfsR binding site overlapped the promoter of afsS, as determined by DNase I protection assay and high-resolution S1 nuclease mapping. The nucleotide-binding domain contributed distinct ATPase and GTPase activity. The phosphorylation of AfsR by AfsK greatly enhanced the DNA-binding activity and modulated the ATPase activity. The DNA-binding ability of AfsR was independent of the ATPase activity. However, the ATPase activity was essential for transcriptional activation of afsS, probably because the energy available from ATP hydrolysis is required for the isomerization of the closed complex between AfsR and RNA polymerase to a transcriptionally competent open complex. Thus, AfsR turns out to be a unique transcriptional factor, in that it is modular, in which DNA-binding and ATPase activities are physically separable, and the two functions are modulated by phosphorylation on serine and threonine residues.

  9. Espanol para Hoteleria y Turismo = Spanish for Travel and Tourism.

    ERIC Educational Resources Information Center

    Montes, Yara G.

    This beginning through advanced Spanish text includes grammar explanations, readings, and exercises with the emphasis on situations involving travel and tourism. The introductory lesson covers the Spanish language, the importance of Spanish in the United States, the Spanish alphabet, pronunciation, capitalization, punctuation, syllabication,…

  10. Publishing Spanish-Language Books in the United States.

    ERIC Educational Resources Information Center

    Lee, Philip

    2002-01-01

    Discusses the need for Spanish language materials as a result of the growth of the Hispanic population, and describes issues faced by one children's book publisher. Topics include how books are selected for translation; Spanish only versus bilingual editions; selecting translators; standard Spanish versus regional Spanish; and information for…

  11. Spanish Courses for Spanish Speakers: Partial Listing of Programs. [and] Spanish Materials Being Used in Courses for Native Spanish Speakers at the Secondary Level. CLEAR Materials Resource Series, Numbers 3 and 5.

    ERIC Educational Resources Information Center

    Dreyfus, Dan; Willetts, Karen

    Two numbers of the CLEAR Materials Resource Series that both deal with teaching Spanish to native Spanish speakers have been combined. Number three provides a brief description of the courses and curricula developed by various school districts for the teaching of Spanish language arts to native speakers of Spanish at the elementary and secondary…

  12. The advantage of first mention in Spanish

    PubMed Central

    CARREIRAS, MANUEL; GERNSBACHER, MORTON ANN; VILLA, VICTOR

    2015-01-01

    An advantage of first mention—that is, faster access to participants mentioned first in a sentence—has previously been demonstrated only in English. We report three experiments demonstrating that the advantage of first mention occurs also in Spanish sentences, regardless of whether the first-mentioned participants are syntactic subjects, and regardless, too, of whether they are proper names or inanimate objects. Because greater word-order flexibility is allowed in Spanish than in English (e.g., nonpassive object-verb-subject constructions exist in Spanish), these findings provide additional evidence that the advantage of first mention is a general cognitive phenomenon. PMID:24203596

  13. The Impact of a Systematic and Explicit Vocabulary Intervention in Spanish with Spanish-Speaking English Learners in First Grade

    ERIC Educational Resources Information Center

    Cena, Johanna; Baker, Doris Luft; Kame'enui, Edward J.; Baker, Scott K.; Park, Yonghan; Smolkowski, Keith

    2013-01-01

    This study examined the impact of a 15-min daily explicit vocabulary intervention in Spanish on expressive and receptive vocabulary knowledge and oral reading fluency in Spanish, and on language proficiency in English. Fifty Spanish-speaking English learners who received 90 min of Spanish reading instruction in an early transition model were…

  14. An Empirical Test of Oklahoma's A-F School Grades

    ERIC Educational Resources Information Center

    Adams, Curt M.; Forsyth, Patrick B.; Ware, Jordan; Mwavita, Mwarumba; Barnes, Laura L.; Khojasteb, Jam

    2016-01-01

    Oklahoma is one of 16 states electing to use an A-F letter grade as an indicator of school quality. On the surface, letter grades are an attractive policy instrument for school improvement; they are seemingly clear, simple, and easy to interpret. Evidence, however, on the use of letter grades as an instrument to rank and improve schools is scant…

  15. Ornicorrugatin, a new siderophore from Pseudomonas fluorescens AF76.

    PubMed

    Matthijs, Sandra; Budzikiewicz, Herbert; Schäfer, Mathias; Wathelet, Bernard; Cornelis, Pierre

    2008-01-01

    From a pyoverdin-negative mutant of Pseudomonas fluorescens AF76 a new lipopeptidic siderophore (ornicorrugatin) could be isolated. It is structurally related to the siderophore of Pseudomonas corrugata differing in the replacement of one Dab unit by Orn. PMID:18386480

  16. Extracting uranium from seawater: Promising AF series adsorbents

    SciTech Connect

    Das, Sadananda; Oyola, Y.; Mayes, Richard T.; Janke, Christopher James; Kuo, Li-Jung; Gill, Gary; Wood, Jordana; Dai, Sheng

    2015-11-02

    Here, a new family of high surface area polyethylene fiber adsorbents (AF series) was recently developed at the Oak Ridge National Laboratory (ORNL). The AF series of were synthesized by radiation-induced graft polymerization of acrylonitrile and itaconic acid (at different monomer/co-monomer mol ratios) onto high surface area polyethylene fibers. The degree of grafting (%DOG) of AF series adsorbents was found to be 154 354%. The grafted nitrile groups were converted to amidoxime groups by treating with hydroxylamine. The amidoximated adsorbents were then conditioned with 0.44M KOH at 80 C followed by screening at ORNL with simulated seawater spiked with 8 ppm uranium. Uranium adsorption capacity in simulated seawater screening ranged from 170-200 g-U/kg-ads irrespective of %DOG. A monomer/co-monomer mol ratio in the range of 7.57-10.14 seemed to be optimum for highest uranium loading capacity. Subsequently, the adsorbents were also tested with natural seawater at Pacific Northwest National Laboratory (PNNL) using flow-through exposure uptake experiments to determine uranium loading capacity with varying KOH conditioning time at 80 C. The highest adsorption capacity of AF1 measured after 56 days of marine testing was demonstrated as 3.9 g-U/kg-adsorbent and 3.2 g-U/kg-adsorbent for 1hr and 3hrs of KOH conditioning at 80 C, respectively. Based on capacity values of several AF1 samples, it was observed that changing KOH conditioning from 3hrs to 1hr at 80 C resulted in 22-27% increase in uranium loading capacity in seawater.

  17. Extracting uranium from seawater: Promising AF series adsorbents

    DOE PAGES

    Das, Sadananda; Oyola, Y.; Mayes, Richard T.; Janke, Christopher James; Kuo, Li-Jung; Gill, Gary; Wood, Jordana; Dai, Sheng

    2015-11-02

    Here, a new family of high surface area polyethylene fiber adsorbents (AF series) was recently developed at the Oak Ridge National Laboratory (ORNL). The AF series of were synthesized by radiation-induced graft polymerization of acrylonitrile and itaconic acid (at different monomer/co-monomer mol ratios) onto high surface area polyethylene fibers. The degree of grafting (%DOG) of AF series adsorbents was found to be 154 354%. The grafted nitrile groups were converted to amidoxime groups by treating with hydroxylamine. The amidoximated adsorbents were then conditioned with 0.44M KOH at 80 C followed by screening at ORNL with simulated seawater spiked with 8more » ppm uranium. Uranium adsorption capacity in simulated seawater screening ranged from 170-200 g-U/kg-ads irrespective of %DOG. A monomer/co-monomer mol ratio in the range of 7.57-10.14 seemed to be optimum for highest uranium loading capacity. Subsequently, the adsorbents were also tested with natural seawater at Pacific Northwest National Laboratory (PNNL) using flow-through exposure uptake experiments to determine uranium loading capacity with varying KOH conditioning time at 80 C. The highest adsorption capacity of AF1 measured after 56 days of marine testing was demonstrated as 3.9 g-U/kg-adsorbent and 3.2 g-U/kg-adsorbent for 1hr and 3hrs of KOH conditioning at 80 C, respectively. Based on capacity values of several AF1 samples, it was observed that changing KOH conditioning from 3hrs to 1hr at 80 C resulted in 22-27% increase in uranium loading capacity in seawater.« less

  18. [Andreas Vesalius in the Spanish Court].

    PubMed

    Izumi, Hyonosuke

    2004-12-01

    After the publication of "Fabrica," Andreas Vesalius entered the Spanish court and became a court physician to Charles the Fifth, Holy Roman Emperor, and then to Philip the Second, Spanish king. The author studied this process and its historical background. The ancestors of Vesalius had close relations with the Hapsburgs and the dukes of BUrgundy, and served them as court physician or a court pharmacist. Vesalius was born in Brussels, obtained his degree at the University of Padua, Italy, became professor of anatomy and surgery there, and published "Tabulae Anatomicae Sex" and "Fabrica."In the ear of the Spanish court, the treatments of Henry the Second, French king, and of Don Carlos, Spanish crown prince, are famous among Vesalius' medical contributions. In the year of his resignation, Charles the Fifth conferred the title of count palatine on Vesalius. PMID:15818875

  19. Poetry for Spanish-Speaking Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1985-01-01

    Describes 12 collections and anthologies, many of them bilingual editions and published in Argentina, Costa Rica, Mexico, and the United States, that include poems by Spanish and Latin American poets. Provides tentative grade levels for each selection. (HOD)

  20. Systematic mapping of the Spanish continental margin

    NASA Astrophysics Data System (ADS)

    Acosta, Juan; Muñoz, Araceli; Uchupi, Elazar

    2012-07-01

    For economic, environmental, recreational, military, and political reasons it is critical for coastal states to have up-to-date information on their marine margins. Spain began to acquire such data 17 years ago. From 1995 to the present, the Spanish Oceanographic Institute (IEO), a research organization of the state, has carried out a systematic geological and geophysical study of the Spanish margins. Among these projects are (1) the hydrographic and oceanographic study of the Spanish Exclusive Economic Zone (EEZ) that was implemented by the Navy Hydrographic Institute (IHM); (2) the Espace Project, a study of the Spanish continental shelf; and (3) the Capesme Project, which created fisheries maps of the Mediterranean Sea. The latter two projects were carried out in collaboration with the Secretariat General of the Sea (SGM).

  1. Intonational phonology description of Porteno Spanish

    NASA Astrophysics Data System (ADS)

    Barjam, John P.

    2003-10-01

    In this study the intonational patterns of Porteno Spanish (PS) are described within an Autosegmental Metrical (AM) (Ladd, 1996) approach. Porteno Spanish is the Spanish spoken in Buenos Aires, Argentina, and because of the influence from Italian and other languages, it differs markedly from varieties of Spanish that have been previously described. Six monolingual PS speakers were recorded saying 99 sentences which include declaratives, interrogatives, imperatives, and focused declarative and interrogative sentences. A ToBI framework, based on the F0 contour, was developed for labeling the sentences intonation. Preliminary results suggest that each phrase contains a somewhat regular pattern: (1) the stressed syllables of content words carry one of five pre-nuclear pitch accents, (2) nuclear pitch accents are more restrictive and tend to vary depending on the sentence type, and (3) boundary tones, both intermediate and intonational, are regular but also vary depending on sentence type.

  2. Spanish Reflexives: A Critique of Pedagogical Descriptions.

    ERIC Educational Resources Information Center

    Lozano, Anthony G.

    1997-01-01

    Discusses pedagogical descriptions in high school textbooks covering Spanish reflexive verb constructions. Points out that these textbooks rarely contain the full reflexive construction displayed with all the grammatical persons and complete English glosses. (17 references) (Author/CK)

  3. [Andreas Vesalius in the Spanish Court].

    PubMed

    Izumi, Hyonosuke

    2004-12-01

    After the publication of "Fabrica," Andreas Vesalius entered the Spanish court and became a court physician to Charles the Fifth, Holy Roman Emperor, and then to Philip the Second, Spanish king. The author studied this process and its historical background. The ancestors of Vesalius had close relations with the Hapsburgs and the dukes of BUrgundy, and served them as court physician or a court pharmacist. Vesalius was born in Brussels, obtained his degree at the University of Padua, Italy, became professor of anatomy and surgery there, and published "Tabulae Anatomicae Sex" and "Fabrica."In the ear of the Spanish court, the treatments of Henry the Second, French king, and of Don Carlos, Spanish crown prince, are famous among Vesalius' medical contributions. In the year of his resignation, Charles the Fifth conferred the title of count palatine on Vesalius.

  4. 40 CFR 180.1206 - Aspergillus flavus AF36; exemption from the requirement of a tolerance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Aspergillus flavus AF36; exemption... FOOD Exemptions From Tolerances § 180.1206 Aspergillus flavus AF36; exemption from the requirement of a... pesticide Aspergillus flavus AF36 in or on cotton, gin byproducts; cotton, hulls; cotton, meal;...

  5. [Munchausen syndrome in Spanish pediatrics].

    PubMed

    Jimenez Hernandez, J L; Figuerido-Poulain, J L

    1996-01-01

    The term Munchausen is used to design patients with "expectable clínical histories full of lies and inventions" in a presumable try to find medical attention. In the Munchausen by proxy syndrome the pediatric patients are victims of their parents psychiatric pathology, who, in spite of the normal aspect that many times have, are really sick and urgently needed of psychiatric treatment. In the spanish psychiatric bibliography we have found 25 cases of Munchausen syndrome that hurt to 20 families. 5 cases were Munchausen, and the remain 20 were Munchausen by Proxy. In this group the majority (13 cases: 65%) were non accidental drug intoxications and in the 20 cases the mother was the fraud author. We concluded remarking that statistics shows a casuistic lower than the real one. A study of the Munchausen by proxy syndrome shows that it is a type of child abuse; so that it is essential to stop the abuse as soon as possible, by a multidisciplinary work. PMID:8900975

  6. Embossed Teflon AF Laminate Membrane Microfluidic Diaphragm Valves

    NASA Technical Reports Server (NTRS)

    Willis, Peter; Hunt, Brian; White,Victor; Grunthaner, Frank

    2008-01-01

    A microfluidic system has been designed to survive spaceflight and to function autonomously on the Martian surface. It manipulates microscopic quantities of liquid water and performs chemical analyses on these samples to assay for the presence of molecules associated with past or present living processes. This technology lies at the core of the Urey Instrument, which is scheduled for inclusion on the Pasteur Payload of the ESA ExoMars rover mission in 2013. Fabrication processes have been developed to make the microfabricated Teflon-AF microfluidic diaphragm pumps capable of surviving extreme temperature excursions before and after exposure to liquid water. Two glass wafers are etched with features and a continuous Teflon membrane is sandwiched between them (see figure). Single valves are constructed using this geometry. The microfabricated devices are then post processed by heating the assembled device while applying pneumatic pressure to force the Teflon diaphragm against the valve seat while it is softened. After cooling the device, the embossed membrane retains this new shape. This solves previous problems with bubble introduction into the fluid flow where deformations of the membrane at the valve seat occurred during device bonding at elevated temperatures (100-150 C). The use of laminated membranes containing commercial Teflon AF 2400 sheet sandwiched between spun Teflon AF 1600 layers performed best, and were less gas permeable than Teflon AF 1600 membranes on their own. Spinning Teflon AF 1600 solution (6 percent in FLOURINERT(Registered TradeMark) FC40 solvent, 3M Company) at 500 rpm for 1.5 seconds, followed by 1,000 rpm for 3 seconds onto Borofloat glass wafers, results in a 10-micron-thick film of extremely smooth Teflon AF. This spinning process is repeated several times on flat, blank, glass wafers in order to gradually build a thick, smooth membrane. After running this process at least five times, the wafer and Teflon coating are heated under vacuum

  7. Spanish Heritage Language Learners' Allocation of Time to Writing Processes in English and Spanish

    ERIC Educational Resources Information Center

    Mikulski, Ariana; Elola, Idoia

    2011-01-01

    This study brings together previous research on writing processes and Spanish heritage language (SHL) learners to obtain a clearer picture of these learners' writing behaviors in English and Spanish. Following a cognitive-oriented framework, the study explores planning time, execution time, monitoring time, accuracy, and fluency. Twelve SHL…

  8. The Acquisition of Prosodic Word Structures in Spanish by Monolingual and Spanish-German Bilingual Children

    ERIC Educational Resources Information Center

    Lleo, Conxita

    2006-01-01

    This article examines the constraints on Prosodic Word production in Spanish by three monolingual and three Spanish-German bilingual children from the beginning of word production until 2;2. It also considers the relationship between Prosodic Words and Phonological Phrases, and in the case of monosyllabic words, it takes into consideration…

  9. Spanish Teachers' Sense of Humor and Student Performance on the National Spanish Exams

    ERIC Educational Resources Information Center

    Swanson, Peter B.

    2013-01-01

    Research suggests that second/foreign language teachers' sense of humor is directly related to many outcomes for teachers and their students. This research investigates the relationship between the perceived sense of humor of in-service Spanish teachers' (n?=?102) and their students' (n?=?5,419) score on the National Spanish Exams…

  10. Espanol para el hispanohablante. Funcion y nocion (Spanish for the Spanish Speaker. Function and Notion).

    ERIC Educational Resources Information Center

    Blanco, George M.; And Others

    A guide to the development of Spanish-language curricula for Spanish-speaking secondary students is intended to help teachers and administrators design programs building on students' existing language strengths. The recommended instructional approach is functional-notional, and local districts are encouraged to use it to adapt their textbooks and…

  11. SCDC Spanish Curricula Units. Spanish SL, Unit 6, Grade 2, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Spanish for second graders is explored in the instructional and assessment activities of the unit six Spanish as a Second Language strand. The function of the strand is to help provide the English-dominant child with the structures and vocabulary needed for effective communication in a bilingual environment. Focus, objective, and materials for…

  12. Teaching Numeric Concepts to Spanish-Speaking Second Graders: English or Spanish Instruction?

    ERIC Educational Resources Information Center

    Denker, Elenor Rubin

    Seventeen Spanish-speaking children received mathematics instruction in either Spanish or English. Numeric concepts were chosen as the content area so that the results could be understood non-verbally at the outset, the teachers ranked the children's abilities in English and math, and no significant difference between groups was found. However,…

  13. Performance of Boer-Spanish and Spanish goats in Texas I: Body weights, fertility, prolificacy, and number of kids weaned.

    PubMed

    Rhone, J A; Waldron, D F; Herring, A D

    2013-10-01

    Production records from 291 Boer-Spanish and Spanish does, collected between 1994 and 2004 in the Edwards Plateau region of West Texas, were examined to compare Boer-Spanish and Spanish does for body weights, fertility, prolificacy, and number of kids weaned. Traits were analyzed using single-trait mixed models. Boer-Spanish does were heavier at birth than Spanish does (2.79 vs. 2.67 kg, P = 0.05) but similar weight at weaning (15.2 vs. 15.0 kg, P = 0.59). Boer-Spanish does had a heavier body weight at breeding than Spanish does (46.5 vs. 43.5 kg, P < 0.01). Boer-Spanish does had similar fertility over 8 annual breeding seasons (0.87 vs. 0.84, P = .22). Boer-Spanish does had an advantage over Spanish does for fertility to a 30-d breeding season (0.53 vs. 0.48; P = .09). Boer-Spanish does produced more kids than Spanish does (1.70 vs. 1.62, P = .09). Boer-Spanish does weaned a similar number of kids (1.30 vs. 1.31, P = .76). Age of doe significantly affected (P < 0.05) both number of kids born and number of kids weaned, with older does giving birth to, and weaning, more kids. Boer-Spanish does had greater birth weight, body weight at breeding, and number of kids born than Spanish does. Boer-Spanish does had a similar number of kids weaned as Spanish does.

  14. Durable Superhydrophobic Surfaces via Spontaneous Wrinkling of Teflon AF.

    PubMed

    Scarratt, Liam R J; Hoatson, Ben S; Wood, Elliot S; Hawkett, Brian S; Neto, Chiara

    2016-03-01

    We report the fabrication of both single-scale and hierarchical superhydrophobic surfaces, created by exploiting the spontaneous wrinkling of a rigid Teflon AF film on two types of shrinkable plastic substrates. Sub-100 nm to micrometric wrinkles were reproducibly generated by this simple process, with remarkable control over the size and hierarchy. Hierarchical Teflon AF wrinkled surfaces showed extremely high water repellence (contact angle 172°) and very low contact angle hysteresis (2°), resulting in droplets rolling off the surface at tilt angles lower than 5°. The wrinkling process intimately binds the Teflon AF layer with its substrate, making these surfaces mechanically robust, as revealed by macroscale and nanoscale wear tests: hardness values were close to that of commercial optical lenses and aluminum films, resistance to scratch was comparable to commercial hydrophobic coatings, and damage by extensive sonication did not significantly affect water repellence. By this fabrication method the size of the wrinkles can be reproducibly tuned from the nanoscale to the microscale, across the whole surface in one step; the fabrication procedure is extremely rapid, requiring only 2 min of thermal annealing to produce the desired topography, and uses inexpensive materials. The very low roll-off angles achieved in the hierarchical surfaces offer a potentially up-scalable alternative as self-cleaning and drag-reducing coatings.

  15. Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival

    PubMed Central

    Fei, Dennis Liang; Motowski, Hayley; Chatrikhi, Rakesh; Gao, Shaojian; Kielkopf, Clara L.; Varmus, Harold

    2016-01-01

    We have asked how the common S34F mutation in the splicing factor U2AF1 regulates alternative splicing in lung cancer, and why wild-type U2AF1 is retained in cancers with this mutation. A human lung epithelial cell line was genetically modified so that U2AF1S34F is expressed from one of the two endogenous U2AF1 loci. By altering levels of mutant or wild-type U2AF1 in this cell line and by analyzing published data on human lung adenocarcinomas, we show that S34F-associated changes in alternative splicing are proportional to the ratio of S34F:wild-type gene products and not to absolute levels of either the mutant or wild-type factor. Preferential recognition of specific 3′ splice sites in S34F-expressing cells is largely explained by differential in vitro RNA-binding affinities of mutant versus wild-type U2AF1 for those same 3′ splice sites. Finally, we show that lung adenocarcinoma cell lines bearing U2AF1 mutations do not require the mutant protein for growth in vitro or in vivo. In contrast, wild-type U2AF1 is required for survival, regardless of whether cells carry the U2AF1S34F allele. Our results provide mechanistic explanations of the magnitude of splicing changes observed in U2AF1-mutant cells and why tumors harboring U2AF1 mutations always retain an expressed copy of the wild-type allele. PMID:27776121

  16. Identification and functional characterization of grass carp IL-17A/F1: An evaluation of the immunoregulatory role of teleost IL-17A/F1.

    PubMed

    Du, Linyong; Feng, Shiyu; Yin, Licheng; Wang, Xinyan; Zhang, Anying; Yang, Kun; Zhou, Hong

    2015-07-01

    In mammals, IL-17A and IL-17F are hallmark cytokines of Th17 cells which act significant roles in eradicating extracellular pathogens. IL-17A and IL-17F homologs nominated as IL-17A/F1-3 have been revealed in fish and their functions remain largely undefined. Here we identified and characterized grass carp IL-17A/F1 (gcIL-17A/F1) in fish immune system. In this regard, both tissue distribution and inductive expression of gcIL-17A/F1 indicated its possible involvement in immune response. Moreover, recombinant gcIL-17A/F1 (rgcIL-17A/F1) was prepared and displayed an ability to enhance pro-inflammatory cytokines (IL-1β, TNF-α and IL-6) mRNA expression in head kidney leukocytes. It is suggestive of that gcIL-17A/F1 may act as a proinflammatory cytokine in fish immunity. Besides, rgcIL-17A/F1 induced gene expression and protein release of grass carp chemokine CXCL-8 (gcCXCL-8) in head kidney cells (HKCs), probably via NF-κB, p38 and Erk1/2 pathways. In particular, culture medium from the HKCs treated by rgcIL-17A/F1 could stimulate peripheral blood leukocytes migration and immunoneutralization of endogenous gcCXCL-8 could partially attenuate this stimulation, suggesting that rgcIL-17A/F1 could recruit immune cells through producing gcCXCL-8 as mammalian IL-17 A and F. Taken together, we not only identified the pro-inflammatory role of gcIL-17A/F1 in host defense, but also provided the basis for clarifying Th17 cells in teleost. PMID:25847875

  17. The Surface Pattern Vb a Vb in Spanish

    ERIC Educational Resources Information Center

    Foster, David William

    1977-01-01

    Describes a study using transformational generative grammar to demonstrate that the frequently used structure "verb a verb" in Spanish is to be interpreted in three ways. Conclusions are drawn for the teaching of Spanish as a foreign language. (AMH)

  18. Noteworthy Books in Spanish for Children and Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1997-01-01

    Lists books recently published in Spanish or translated into Spanish for children and adolescents. The 23 titles annotated include picture books, renditions of the classics for young people, science books, novels, and romances. (SLD)

  19. Medical Spanish for Majors: Open Wide and Say "Yes."

    ERIC Educational Resources Information Center

    Mason, Keith

    1991-01-01

    Argues that the need exists for a medical Spanish course designed specifically for Spanish majors, especially for those students who are following the pre-med sequence required for entrance to medical school. (20 references) (GLR)

  20. El idioma espanol en el mundo (The Spanish Language in the World)

    ERIC Educational Resources Information Center

    Baron Castro, Rodolfo

    1975-01-01

    This report to the Office of Ibero-American Education concerns the status of Spanish in five areas: 1) A program on Spanish in the Philippines; 2) Spanish in the United States; 3) Cooperation with the Commission on Spanish of UNESCO; 4) A professorship in Bogota, and 5) Spanish scientific terminology. (Text is in Spanish.) (CHK)

  1. Improvement and biological applications of fluorescent probes for zinc, ZnAFs.

    PubMed

    Hirano, Tomoya; Kikuchi, Kazuya; Urano, Yasuteru; Nagano, Tetsuo

    2002-06-12

    The development and cellular applications of novel fluorescent probes for Zn2+, ZnAF-1F, and ZnAF-2F are described. Fluorescein is used as a fluorophore of ZnAFs, because its excitation and emission wavelengths are in the visible range, which minimizes cell damage and autofluorescence by excitation light. N,N-Bis(2-pyridylmethyl)ethylenediamine, used as an acceptor for Zn2+, is attached directly to the benzoic acid moiety of fluorescein, resulting in very low quantum yields of 0.004 for ZnAF-1F and 0.006 for ZnAF-2F under physiological conditions (pH 7.4) due to the photoinduced electron-transfer mechanism. Upon the addition of Zn2+, the fluorescence intensity is quickly increased up to 69-fold for ZnAF-1F and 60-fold for ZnAF-2F. Apparent dissociation constants (K(d)) are in the nanomolar range, which affords sufficient sensitivity for biological applications. ZnAFs do not fluoresce in the presence of other biologically important cations such as Ca2+ and Mg2+, and are insensitive to change of pH. The complexes with Zn2+ of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2+ complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence around neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. For application to living cells, the diacetyl derivative of ZnAF-2F, ZnAF-2F DA, was synthesized. ZnAF-2F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-2F, which is retained in the cells. Using ZnAF-2F DA, we could measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices.

  2. Structural Priming in Spanish as Evidence of Implicit Learning

    ERIC Educational Resources Information Center

    Gámez, Perla B.; Shimpi, Priya M.

    2016-01-01

    This study uses a structural priming technique with young Spanish speakers to test whether exposure to a rare syntactic form in Spanish ("fue"-passive) would increase the production and comprehension of that form. In Study 1, 14 six-year-old Spanish speakers described pictures of transitive scenes. This baseline study revealed that…

  3. Conversational Spanish for Law Enforcement Personnel. Level 1.

    ERIC Educational Resources Information Center

    Moffett, Oren E.

    The textbook is designed to satisfy the linguistic needs of law enforcement personnel who deal with monolingual Spanish speakers. The goal of the text is to enable the student to communicate in Spanish. The material stresses career-oriented "need-to-know" Spanish, relevant cultural awareness materials, practical role-playing exercises and task…

  4. Apuntes sobre Latinismos en Espanol (Notes on Latinisms in Spanish)

    ERIC Educational Resources Information Center

    Perez B., L. A.

    1977-01-01

    Several Latinisms appear in Latin American Spanish, which would logically be farther from its Latin roots than Spanish in Spain. The existence of these elements and their importance as linguistic facts is analyzed here. Four words are treated: "Cliente,""cuadrar,""cuarto" and "rabula." (Text is in Spanish.) (CHK)

  5. Teaching Spanish Subject Matters to College Students in the USA.

    ERIC Educational Resources Information Center

    Cabedo-Timmons, Guada

    This paper discusses how to teach Spanish subject matter to U.S. college students, focusing on one professor's experiences teaching an upper level Spanish class, Spanish Subject Matters, to students who plan to be K-12 or bilingual classroom teachers. The paper stresses the current need for bilingual teachers, suggesting that a teacher does not…

  6. On the L1 Attrition of the Spanish Present Tense

    ERIC Educational Resources Information Center

    Cuza, Alejandro

    2010-01-01

    This study examines the potential native language (L1) attrition of the ongoing value of the Spanish present tense among long-term Spanish immigrants. Based on the assumption of second-language (L2) transfer and proposals on the permeability of interface-conditioned structures, it is hypothesized that long-term Spanish immigrants will show…

  7. Linguistic Transfer in Andean Spanish: Syntax or Pragmatics?

    ERIC Educational Resources Information Center

    Muntendam, Antje

    2009-01-01

    This dissertation uses the generative framework to study the syntax and pragmatics of word order variation in the Andean Spanish of Bolivia and Ecuador. While Standard Spanish has basic order SVO, in Andean Spanish the object frequently appears in preverbal position, resulting in alternative orders (e.g. OVS). Previous studies have attributed this…

  8. On the Internal Structure of Spanish Verbless Clauses

    ERIC Educational Resources Information Center

    Gonzalez-Rivera, Melvin

    2011-01-01

    In this dissertation I discuss several aspects of the syntax, semantics and discourse properties of what I call Spanish verbless clauses -i.e. non-finite utterances with clausal properties: Spanish PredNP "muy listo este tio" "very intelligent this guy", Spanish PP complement clause "me sorprende lo caro del piso" "it amazes me how expensive this…

  9. 16 CFR 455.5 - Spanish language sales.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Spanish language sales. 455.5 Section 455.5 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.5 Spanish language sales. If you conduct a sale in Spanish, the window form required by §...

  10. 16 CFR 455.5 - Spanish language sales.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Spanish language sales. 455.5 Section 455.5 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.5 Spanish language sales. If you conduct a sale in Spanish, the window form required by §...

  11. 16 CFR 455.5 - Spanish language sales.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Spanish language sales. 455.5 Section 455.5 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.5 Spanish language sales. If you conduct a sale in Spanish, the window form required by §...

  12. Input, Output, and Negotiation of Meaning in Spanish Conversation Classes

    ERIC Educational Resources Information Center

    Rondon-Pari, Graziela

    2014-01-01

    This research study is based on the analysis of speech in three Spanish conversation classes. Research questions are: What is the ratio of English and Spanish spoken in class? Is classroom speech more predominant in students or the instructor? And, are teachers' beliefs in regards to the use of English and Spanish consistent with their…

  13. 27 CFR 24.214 - Spanish type blending sherry.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Spanish type blending... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Production of Other Than Standard Wine § 24.214 Spanish..., produced under this section, is designated “Spanish Type Blending Sherry.” Upon removal, the...

  14. Recent Noteworthy Books in Spanish for Young Children.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1994-01-01

    Reviews 19 books in Spanish for young, Spanish-speaking children or others who may wish to learn Spanish. The titles include a variety of informative books and entertaining stories on topics such as pirates, trains, giants, art, and animals of all kinds. (TJQ)

  15. VOCABULARY GUIDE OF COGNATE WORDS IN SPANISH AND ENGLISH.

    ERIC Educational Resources Information Center

    KRIPPNER, STANLEY

    A VOCABULARY GUIDE OF COGNATE WORDS IN ENGLISH AND SPANISH IS PRESENTED. THE VALUE OF THE GUIDE RESTS ON THE ASSUMPTIONS THAT THE LEARNING OF SIMILAR WORDS IN BOTH LANGUAGES COULD CHANGE SPANISH-SPEAKING AMERICAN PUPILS' NEGATIVE ATTITUDE ABOUT ENGLISH AS WELL AS INCREASE THEIR VOCABULARY. WORDS IN THE "VELAZQUEZ SPANISH AND ENGLISH DICTIONARY" OF…

  16. A Glossary of Spanish-American Agricultural Terms.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.; Rund, Maria T.

    The Spanish-English and English-Spanish glossary of agricultural and supporting terms is an expansion of an earlier glossary intended for North American agricultural specialists working in Latin America. It contains terminology from 50 articles in Spanish on Latin American agricultural topics. A list of those sources is included. (MSE)

  17. A Responsive, Integrative Spanish Curriculum at UNC Charlotte

    ERIC Educational Resources Information Center

    Doyle, Michael S.

    2010-01-01

    The Spanish program at UNC Charlotte is timely and responsive because it is designed to meet documented societal (job market) needs in today's and tomorrow's global village and economy by providing graduates with strong specialties in English-Spanish translating and in business Spanish. It is integrative in that it does so while maintaining its…

  18. "Ficciones," Jorge Luis Borges. Performance Guides to Spanish Texts.

    ERIC Educational Resources Information Center

    Gies, David Thatcher, Comp.

    This performance guide is the result of work conducted at the University of Virginia's National Endowment for the Humanities Summer Institute, 1989, on "Spanish Literature in Performance," in which 25 secondary school Spanish teachers studied Spanish texts from the perspective of classroom performance to deepen knowledge of the texts and discover…

  19. La Dicha de Los Libros--Children's Books in Spanish.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2000-01-01

    Reviews a collection of high-quality books in Spanish which can help encourage Spanish-speaking children and adolescents to read. From creative books for the very young to the lives of famous women, to fantasies and animated traditional tales, these recently published books are designed to appeal to Spanish speakers and those wishing to learn…

  20. Recent Noteworthy Books in Spanish for Young Readers.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1992-01-01

    This annotated bibliography for school library media specialists and teachers lists 34 recent books that encourage reading by Spanish-speaking students or others who wish to learn Spanish. Grade levels are indicated for each title, and a list of U.S. dealers for books in Spanish for children and adolescents is included. (LRW)

  1. Inglaterra, primitiva colonia espanola (England, Primitive Spanish Colony)

    ERIC Educational Resources Information Center

    Til, Brianes

    1975-01-01

    The author fantasizes that at some point in the distant past England was a Spanish colony. He supports his thesis by revealing fantastic etymologies of some English place names showing the influence of Spanish on English, for example "Surrey" comes from "su rey." (Text is in Spanish.) (TL)

  2. Spanish in Four Continents: Studies in Language Contact and Bilingualism.

    ERIC Educational Resources Information Center

    Silva-Corvalan, Carmen, Ed.

    Papers on Spanish bilingualism and Spanish in contact with other languages include: "The Study of Language Contact: An Overview of the Issues" (Carmen Silva-Corvalan); "Language Mixture: Ordinary Processes, Extraordinary Results" (Sarah G. Thomason); "The Impact of Quichua on Verb Forms Used in Spanish Requests in Otavalo, Ecuador" (Joni Kay…

  3. Binding sites for two novel phosphoproteins, 3AF5 and 3AF3, are required for rbcS-3A expression.

    PubMed Central

    Sarokin, L P; Chua, N H

    1992-01-01

    Previous studies of boxes II (-151 to -138) and III (-125 to -114), binding sites for the nuclear factor GT-1 within the -166 deleted promoter of the ribulose-1,5-bisphosphate carboxylase-3A (rbcS-3A) gene, suggested that GT-1 might act in concert with an additional protein to confer light-responsive rbcS-3A expression. In this work, S1 analysis of RNA isolated from transgenic tobacco plants carrying mutant rbcS-3A constructs led to the identification of two short sequences located at the 5' and 3' ends of box III that are required for expression. These two sequences serve as binding sites for two novel proteins, 3AF5 and 3AF3. Gel shift studies using tetramerized binding sites for both 3AF5 and 3AF3 showed that complexes with faster mobilities were formed using nuclear extracts prepared from dark-adapted plants compared with those from light-grown tobacco plants. Phosphatase treatment of extracts from light-grown plants resulted in the formation of complexes with faster mobility. Although the binding of 3AF3 to its target site is dependent upon phosphorylation, the binding of 3AF5 does not appear to be affected by its phosphorylation state. These results suggest that the phosphorylated forms of both 3AF5 and 3AF3 are required for -166 rbcS-3A expression but that the mechanisms differ by which phosphorylation regulates the activities of 3AF5 and 3AF3. PMID:1498605

  4. Spanish-Hispanic Culture from A to V (Actualidades to Venezuela): 72 Spanish-Language Interdisciplinary Cultural Themes with Suggested Resource Materials and Activities.

    ERIC Educational Resources Information Center

    Moore, Merriam M.

    This guidebook is intended for use by teachers of Spanish (FLES through college level) and by teachers in Spanish bilingual programs. It lists all of the Spanish-speaking countries and 72 Spanish-language cultural themes, such as "Actualidades" (Current Events), "Carreras y espanol comercial" (Careers and Commercial Spanish), "Deportes" (Sports),…

  5. Senales de Trafico. Ingles-Espanol = Traffic Signs. English-Spanish [and] English-Spanish Road Signs for American Tourists.

    ERIC Educational Resources Information Center

    Grosse, Philip

    Two English/Spanish bilingual glossaries define words and phrases found on traffic signs. The first is an extensive alphabetical checklist of sign messages, listed in English with translations in Spanish. Some basic traffic and speed limit rules are included. The second volume, in Spanish-to-English form, is a pocket version designed for American…

  6. Curtain Up! Contemporary Children's Plays in Spanish (and) in Spanish: Folklore for Children and Health Books for Adolescents.

    ERIC Educational Resources Information Center

    Ada, Alma Flor; Schon, Isabel

    1987-01-01

    The first of two articles presents a review of children's plays written in Spanish, including the authors' approaches and underlying themes. The second, an annotated bibliography of children's folklore and health books for adolescents in Spanish, includes a directory of eight U.S. dealers in Spanish books. (CLB)

  7. The Development and Validation of an Auditory Perception Test in Spanish for Hispanic Children Receiving Reading Instruction in Spanish.

    ERIC Educational Resources Information Center

    Morrison, James A.; Michael, William B.

    1982-01-01

    A Spanish auditory perception test, La Prueba de Analisis Auditivo, was developed and administered to 158 Spanish-speaking Latino children, kindergarten through grade 3. Psychometric data for the test are presented, including its relationship to SOBER, a criterion-referenced Spanish reading measure. (Author/BW)

  8. Comparison of Spanish Morphology in Monolingual and Spanish-English Bilingual Children with and without Language Impairment

    ERIC Educational Resources Information Center

    Morgan, Gareth P.; Restrepo, M. Adelaida; Auza, Alejandra

    2013-01-01

    This study compares Spanish morphosyntax error types and magnitude in monolingual Spanish and Spanish-English bilingual children with typical language development (TD) and language impairment (LI). Performance across groups was compared using cloze tasks that targeted articles, clitics, subjunctives, and derivational morphemes in 57 children.…

  9. The Power of Belief: Spanish Teachers' Sense of Efficacy and Student Performance on the National Spanish Examinations

    ERIC Educational Resources Information Center

    Swanson, Pete

    2014-01-01

    In this study, the researcher investigated Spanish teachers' sense of efficacy as it relates to their students' achievement on the AATSP National Spanish Examinations. Results suggest that there is a link between Spanish teacher efficacy and students' scores on the exams. That is, the higher one's belief about his or her…

  10. The Advancing State of AF-M315E Technology

    NASA Technical Reports Server (NTRS)

    Masse, Robert; Spores, Ronald A.; McLean, Chris

    2014-01-01

    The culmination of twenty years of applied research in hydroxyl ammonium nitrate (HAN)-based monopropellants, the NASA Space Technology mission Directorate's (STMD) Green Propellant Infusion Mission (GPIM) will achieve the first on-orbit demonstration of an operational AF-M315E green propellant propulsion system by the end of 2015. Following an contextual overview of the completed flight design of the GPIM propellant storage and feed system, results of first operation of a flight-representative heavyweight 20-N engineering model thruster (to be conducted in mid-2014) are presented with performance comparisons to prior lab model (heavyweight) test articles.

  11. Reading difficulties in Spanish adults with dyslexia.

    PubMed

    Suárez-Coalla, Paz; Cuetos, Fernando

    2015-04-01

    Recent studies show that dyslexia persists into adulthood, even in highly educated and well-read people. The main characteristic that adults with dyslexia present is a low speed when reading. In Spanish, a shallow orthographic system, no studies about adults with dyslexia are available; and it is possible that the consistency of the orthographic system favours the reading fluency. The aim of this study was to get an insight of the reading characteristics of Spanish adults with dyslexia and also to infer the reading strategies that they are using. For that purpose, a group of 30 dyslexics (M age = 32 years old) and an age-matched group of 30 adults without reading disabilities completed several phonological and reading tasks: phonological awareness tasks, rapid automatic naming, lexical decision, word and pseudoword reading, letter detection and text reading. The results showed that highly educated Spanish dyslexics performed significantly worse than the control group in the majority of the tasks. Specifically, they showed difficulties reading long pseudowords, indicating problems in automating the grapheme-phoneme rules, but they also seem to present difficulties reading words, which indicate problems with the lexical route. It seems that the Spanish dyslexic adults, as in deep orthographies, continue having difficulties in phonological awareness tasks, rapid naming and reading.

  12. Reading Levels of Spanish Deaf Students

    ERIC Educational Resources Information Center

    Monreal, S. T.; Hernandez, R. S.

    2005-01-01

    The Reading Levels of a population of 93 Spanish deaf students were examined. All study participants had prelingual profound hearing loss; their ages ranged from 9 to 20 years. All were enrolled in compulsory education during 2002-2003 in the Canary Islands (Spain). They were evaluated with sentence and text comprehension subtests from the…

  13. Cultural Myopia: A Challenge to Spanish Education.

    ERIC Educational Resources Information Center

    Cowan, Bryan J.; Perez-Dominguez, Servando

    1996-01-01

    Considers current thinking about intercultural attitudes in Spain to demonstrate reasons why the Spanish approach to interculturalism, particularly in schools, has not been at the forefront of societal, governmental, or educational thinking. Discusses the dangers of ignoring immigrants' needs and abilities within the community and the…

  14. Lexical Connection: Semiterm Grammatical Patterns in Spanish

    ERIC Educational Resources Information Center

    Ferrero, Carmen Lopez

    2012-01-01

    The aim of this article is to describe the grammatical patterns of a set of nouns frequently used in Spanish specialized discourse: the so-called "semiterms". The following nouns were selected for the study: "problema" "problem", "resultado" "result", "motivo" "motive/reason", "razon" "reason", and "consecuencia" "consequence". Apart from…

  15. English-Spanish Verbatim Translation Exam.

    ERIC Educational Resources Information Center

    Stansfield, Charles W.; And Others

    The development and validation of the English-Spanish Verbatim Translation Exam (ESVTE) is described. The test is for use by the Federal Bureau of Investigation (FBI) in the selection of applicants for the positions of Language Specialist or Contract Linguist. The report is divided into eight sections. Section 1 describes the need for the test,…

  16. The Cultural Content of Business Spanish Texts.

    ERIC Educational Resources Information Center

    Grosse, Christine Uber; Uber, David

    A study examined eight business Spanish textbooks for cultural content by looking at commonly appearing cultural topics and themes, presentation of cultural information, activities and techniques used to promote cultural understanding, and incorporation of authentic materials. The texts were evenly divided among beginning, intermediate, and…

  17. Spanish for Nurses: An Interdisciplinary Approach.

    ERIC Educational Resources Information Center

    Medina, Elizabeth R.

    Courses in Spanish for nurses at Loretto Heights College in Colorado combine language instruction, cross-cultural studies, instruction in medical problems particular to certain groups, medical systems and philosophy, and participation in a college-wide interdisciplinary program entitled "Values in Concert." In this program, sets of three courses…

  18. Perceptual prothesis in native Spanish speakers

    NASA Astrophysics Data System (ADS)

    Theodore, Rachel M.; Schmidt, Anna M.

    2003-04-01

    Previous research suggests a perceptual bias exists for native phonotactics [D. Massaro and M. Cohen, Percept. Psychophys. 34, 338-348 (1983)] such that listeners report nonexistent segments when listening to stimuli that violate native phonotactics [E. Dupoux, K. Kakehi, Y. Hirose, C. Pallier, and J. Mehler, J. Exp. Psychol.: Human Percept. Perform. 25, 1568-1578 (1999)]. This study investigated how native-language experience affects second language processing, focusing on how native Spanish speakers perceive the English clusters /st/, /sp/, and /sk/, which represent phonotactically illegal forms in Spanish. To preserve native phonotactics, Spanish speakers often produce prothetic vowels before English words beginning with /s/ clusters. Is the influence of native phonotactics also present in the perception of illegal clusters? A stimuli continuum ranging from no vowel (e.g., ``sku'') to a full vowel (e.g., ``esku'') before the cluster was used. Four final vowel contexts were used for each cluster, resulting in 12 sCV and 12 VsCV nonword endpoints. English and Spanish listeners were asked to discriminate between pairs differing in vowel duration and to identify the presence or absence of a vowel before the cluster. Results will be discussed in terms of implications for theories of second language speech perception.

  19. Spanish Universities and the "Ranking 2005" Initiative

    ERIC Educational Resources Information Center

    De Miguel, Jesus M.; Vaquera, Elizabeth; Sanchez, Jara D.

    2005-01-01

    This article assesses the quality of the Spanish higher education system, focusing mainly on the methodological challenges that the existence of public and private universities represents in the calculation of global higher education rankings. Researchers from the University of Barcelona and the University of Pennsylvania calculated the first…

  20. Spanish for Agricultural Purposes: The Basic Manual.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.; And Others

    This manual, part of a one-semester course for North American agriculture specialists preparing to work in Latin America, is built around specimens of agricultural writing in Spanish. The manual contains 12 lessons on general agriculture, sugar production, grain production, geography, forestry, animal husbandry, soy bean production, agricultural…

  1. Spanish for Agricultural Purposes: The Audio Program.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.; And Others

    The manual is meant to accompany and supplement the basic manual and to serve as support to the audio component of "Spanish for Agricultural Purposes," a one-semester course for North American agriculture specialists preparing to work in Latin America, consists of exercises to supplement readings presented in the course's basic manual and to…

  2. The Pedestrian Behaviour of Spanish Adolescents

    ERIC Educational Resources Information Center

    Sullman, M. J. M.; Gras, M. E.; Font-Mayolas, S.; Masferrer, L.; Cunill, M.; Planes, M.

    2011-01-01

    Adolescent pedestrians are a particularly vulnerable group of road users. This research tested the applicability of the recently developed Adolescent Road user Behaviour Questionnaire (ARBQ) amongst a sample of 2006 Spanish adolescents. Confirmatory Factor Analysis of the full scale found that the original three factors did not adequately fit the…

  3. Selecting Spanish Books in the Elementary School

    ERIC Educational Resources Information Center

    Corona, Elia

    2007-01-01

    In this article, the author recommends a certain criteria for selecting Spanish-language books for elementary students such as cultural factors, setting, time, age, language and visuals. She also enumerates some authors and a listing of their many bilingual texts, which can be used to enrich a school or classroom library.

  4. Stroke Knowledge in Spanish-speaking populations

    PubMed Central

    Hawkes, Maximiliano A; Ameriso, Sebastián F; Willey, Joshua Z

    2015-01-01

    Background Spanish is the second most spoken language in the world. Spanish-speaking populations (SSP) have heterogeneous cultural backgrounds, racial and ethnical origins, economic status, and access to health care systems. There are no published reviews about stroke knowledge in SSP. We reviewed the existing literature addressing stroke knowledge among SSP and propose future directions for research. Summary We identified 18 suitable studies by searching PubMed, Lilacs, Scopus, Embase, Cochrane and Scielo databases, and looking at reference lists of eligible articles. We also included 2 conference abstracts. Data related to stroke knowledge from studies of Spanish-speakers was analyzed. Key messages Little is known about stroke knowledge in SSP, especially in Latin America. Information is poor even among subjects at risk, stroke patients, stroke survivors, and health care providers. “Ictus”, the word used for stroke in Spanish, is largely unrecognized among subjects at risk. Furthermore, access to medical care and presence of neurologists are suboptimal in many regions. There are several potential issues to solve regarding stroke knowledge and stroke care in SSP. Programs to educate the general population and non-neurologists medical providers in stroke and telemedicine may be suitable options to improve the present situation. PMID:25871697

  5. Sequencing Stories in Spanish and English.

    ERIC Educational Resources Information Center

    Steckbeck, Pamela Meza

    The guide was designed for speech pathologists, bilingual teachers, and specialists in English as a second language who work with Spanish-speaking children. The guide contains twenty illustrated stories that facilitate the learning of auditory sequencing, auditory and visual memory, receptive and expressive vocabulary, and expressive language…

  6. Spanish Education during the 1980s.

    ERIC Educational Resources Information Center

    Benavent, Jose A.

    1980-01-01

    If we consider the political, social, and economic factors on which the Spanish educational system rests, short-term prospects cannot be optimistic. Futurological studies are lacking. Projections for the 1980s must take account of four issues: the crisis in social values, energy problems, political change, and the regional autonomy question.…

  7. Singular and Plural Pronominal Reference in Spanish

    ERIC Educational Resources Information Center

    Gelormini-Lezama, Carlos; Almor, Amit

    2014-01-01

    In two self-paced, sentence-by-sentence reading experiments, we examined the difference in the processing of Spanish discourses containing overt and null pronouns. In both experiments, antecedents appeared in a single phrase ("John met Mary") or in a conjoined phrase ("John and Mary met"). In Experiment 1, we compared reading…

  8. A Practical Guide to Teaching Preschool Spanish.

    ERIC Educational Resources Information Center

    Newton, Dianne Lynne

    A curriculum for preschool Spanish instruction, consisting of a list of objectives, a pupil evaluation system, and 26 lesson plans, is presented. The curriculum is designed as an enrichment component for the preschool classroom and is best suited for four-year-old children who have already mastered the same concepts in English. The lessons utilize…

  9. Survival Spanish: Buzz Word or Mandate?

    ERIC Educational Resources Information Center

    Lillyman, Kathryn

    1993-01-01

    The development and instruction of a course in survival Spanish at Sauk Valley Community College (Illinois) are described. The course, taught for over 15 years and targeted at groups such as teachers, nurses, social workers, counselors, and secretaries, is offered as a model for courses in real-life communication for a variety of professions.…

  10. Reading Difficulties in Spanish Adults with Dyslexia

    ERIC Educational Resources Information Center

    Suárez-Coalla, Paz; Cuetos, Fernando

    2015-01-01

    Recent studies show that dyslexia persists into adulthood, even in highly educated and well-read people. The main characteristic that adults with dyslexia present is a low speed when reading. In Spanish, a shallow orthographic system, no studies about adults with dyslexia are available; and it is possible that the consistency of the orthographic…

  11. Business Spanish: Role Playing for Oral Proficiency.

    ERIC Educational Resources Information Center

    Doyle, Michael Scott

    The situation card used in the American Council on the Teaching of Foreign Languages/Educational Testing Service (ACTFL/ETS) Oral Proficiency Interview provides a kind of linguistic-topographical map of the student's foreign language ability by measuring what the student of business Spanish is able or unable to do in business situations in that…

  12. Plant Nutrition in Spanish Secondary Textbooks

    ERIC Educational Resources Information Center

    Gonzalez-Rodriguez, Concepcion; Garcia-Barrios, Susana; Martinez-Lozada, Cristina

    2009-01-01

    In this paper, the authors analyse the conceptual contents related to plant nutrition in the widely-used school texts of six Spanish publishers. An analysis dossier was elaborated based on the epistemological and pedagogical study of this subject. The publishers deal with the issue of plant nutrition at three different levels (multicellular,…

  13. Editing Contemporary Spanish Literature for the Classroom

    ERIC Educational Resources Information Center

    Yalden, Janice

    1977-01-01

    A method is outlined for using works of Spanish literature at the intermediate level. This approach is illustrated, using three novels: "El Rapto" (Ayala), "El Tunel" (Sabato), and "Nada" (Laforet). A key passage is studied in depth, topics are assigned for extension of the content, and a composition is written. (CFM)

  14. Hiatus Resolution in Spanish: An Experimental Study

    ERIC Educational Resources Information Center

    Souza, Benjamin J.

    2010-01-01

    In Spanish, adjacent vowels across and within word boundaries are either in hiatus or form a diphthong. Generally, when either of the unstressed high vowels /i/ and /u/ appears next to any of the other vowels /e/, /a/, or /o/ the result is a diphthong (i.e., "puerta" "door" less than [pwer.ta], "miel" "honey" less than [mjel], and so on). All…

  15. Reading difficulties in Spanish adults with dyslexia.

    PubMed

    Suárez-Coalla, Paz; Cuetos, Fernando

    2015-04-01

    Recent studies show that dyslexia persists into adulthood, even in highly educated and well-read people. The main characteristic that adults with dyslexia present is a low speed when reading. In Spanish, a shallow orthographic system, no studies about adults with dyslexia are available; and it is possible that the consistency of the orthographic system favours the reading fluency. The aim of this study was to get an insight of the reading characteristics of Spanish adults with dyslexia and also to infer the reading strategies that they are using. For that purpose, a group of 30 dyslexics (M age = 32 years old) and an age-matched group of 30 adults without reading disabilities completed several phonological and reading tasks: phonological awareness tasks, rapid automatic naming, lexical decision, word and pseudoword reading, letter detection and text reading. The results showed that highly educated Spanish dyslexics performed significantly worse than the control group in the majority of the tasks. Specifically, they showed difficulties reading long pseudowords, indicating problems in automating the grapheme-phoneme rules, but they also seem to present difficulties reading words, which indicate problems with the lexical route. It seems that the Spanish dyslexic adults, as in deep orthographies, continue having difficulties in phonological awareness tasks, rapid naming and reading. PMID:25836629

  16. A Spanish Borderlands Community: San Antonio.

    ERIC Educational Resources Information Center

    Teja, Jesus F. de la

    2000-01-01

    Discusses the founding of San Antonio, originally San Antonio de Bexar, which, in 1718, came into being as a military settlement involved in Spanish imperial defensive measures. Focuses on the development and continued growth of San Antonio, Texas's most populous city in the 19th century. (CMK)

  17. Current Usage of Relative Pronouns in Spanish.

    ERIC Educational Resources Information Center

    Ozete, Oscar

    1981-01-01

    Examines variations in current usage that pose problems in teaching Spanish relative pronouns. Discusses their treatment in first-year college textbooks, in the professional literature and in newspapers and magazines prose. Attempts to provide a description of the use of these pronouns applicable to classroom presentation. (MES)

  18. Children's Literature Studytour of Spanish America

    ERIC Educational Resources Information Center

    Shachter, Jacqueline

    1975-01-01

    Describes a tour of several Spanish American countries to study the children's literature and culture. Discussion focuses on the children's literature found in theatrical performances, government-sponsored magazines, schools, and libraries. Also discussed are the writers and illustrators who create for children. (JMB)

  19. Elaboration and Simplification in Spanish Discourse

    ERIC Educational Resources Information Center

    Granena, Gisela

    2008-01-01

    This article compares spoken discourse models in Spanish as a second language textbooks and online language learning resources with naturally occurring conversations. Telephone service encounters are analyzed from the point of view of three different dimensions of authenticity: linguistic, sociolinguistic, and psycholinguistic. An analysis of 20…

  20. Stance and the Subjunctive in Isleno Spanish

    ERIC Educational Resources Information Center

    Coles, Felice A.

    2012-01-01

    Isleno Spanish speakers maintain few contexts firmly in the subjunctive (for example, adverbial clauses with the conjunctions "para que" and "antes que" and nominal clauses with "querer"), with most other semantic or syntactic categories optionally licensing the subjunctive. This study will outline the obligatory and optional uses of present and…

  1. Spanish Language Briefs for Parents, 1995.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Rural Education and Small Schools, Charleston, WV.

    This packet contains six briefs developed specifically for Spanish-speaking parents of Mexican origin, and English translations of the briefs. In plain language, these briefs state what researchers and practitioners have learned about various ways parents can help their children do well in school. Titles of the briefs are (1) "Apoyando el…

  2. Soldadura (Welding). Spanish Translations for Welding.

    ERIC Educational Resources Information Center

    Hohhertz, Durwin

    Thirty transparency masters with Spanish subtitles for key words are provided for a welding/general mechanical repair course. The transparency masters are on such topics as oxyacetylene welding; oxyacetylene welding equipment; welding safety; different types of welds; braze welding; cutting torches; cutting with a torch; protective equipment; arc…

  3. Introducing Quality Assurance in the Spanish University.

    ERIC Educational Resources Information Center

    Mora, Jose-Gines; Vidal, Javier

    1998-01-01

    Discussion of the introduction of quality assurance into Spanish universities gives a brief recent history of the university system, describes first experiences in quality assessment during the 1990s and their results, and explains the structure and outcomes of the 1995 institutionalization of a national program for institutional evaluation.…

  4. Governance in Spanish Universities: Changing Paradigms

    ERIC Educational Resources Information Center

    Ion, Georgeta; Castro, Diego

    2012-01-01

    This article reviews the current model of governance within Spanish universities, focusing on the areas of state regulation, academic goals, and organizational management. A qualitative approach was adopted for this research, comprising the use of a survey and a focus group. The conclusions of this study provide some insights into the new…

  5. Family Planning: Bosnian, Russian, Spanish, Nuer.

    ERIC Educational Resources Information Center

    Anoka County Community Health and Environmental Services, Coon Rapids, MN.

    This guide provides information in English, Bosnian, Russian, Spanish, and Nuer on family planning. Topics covered include a variety of birth control methods: abstinence, condoms, contraceptive foam, birth control pills, the Depo-Provera shot, the Norplant implant, diaphragms, intrauterine devices, natural family planning, sterilization, and the…

  6. Spontaneous Language Markers of Spanish Language Impairment

    ERIC Educational Resources Information Center

    Simon-Cereijido, Gabriela; Gutierrez-Clellen, Vera F.

    2007-01-01

    Spanish-speaking (SS) children with language impairment (LI) present with deficits in morphology and verb argument structure. These language areas may be useful for clinical identification of affected children. This study aimed to evaluate the discrimination accuracy of spontaneous language measures with SS preschoolers to tease out what…

  7. AF64A-induced brain damage and its relation to dementia.

    PubMed

    Hörtnagl, H

    1994-01-01

    Several data obtained in the AF64A-model are of particular relevance for our understanding of the pathogenesis and progression of Alzheimer's disease. The AF64A-induced withdrawal of cholinergic function in the rat hippocampus was associated with reversible functional changes in other neurotransmitters, including noradrenaline, serotonin, somatostatin and glutamate, thereby mimicking changes in Alzheimer's disease. Identical changes in markers for synaptic vesicles were found in Alzheimer's disease and AF64A-model. A study on the role of gender revealed a higher susceptibility to the neurotoxic action of AF64A in female rats. The cholinergic deficit was also responsible for a disinhibition of the negative feedback regulation of glucocorticoids. Increased exposure to glucocorticoids, however, enhanced the vulnerability of hippocampal cholinergic neurons to AF64A. These data indicate that the AF64A-induced cholinergic deficit in the rat brain represents a reliable tool to study several mechanisms possibly involved in Alzheimer's disease.

  8. Characterization of Soil Organic Matter from African Dark Earth (AfDE) Soils

    NASA Astrophysics Data System (ADS)

    Plante, A. F.; Fujiu, M.; Ohno, T.; Solomon, D.; Lehmann, J.; Fraser, J. A.; Leach, M.; Fairhead, J.

    2014-12-01

    Anthropogenic Dark Earths are soils generated through long-term human inputs of organic and pyrogenic materials. These soils were originally discovered in the Amazon, and have since been found in Australia and in this case in Africa. While tropical soils are typically characterized by low soil organic matter (SOM) concentrations, African Dark Earths (AfDE) are black, highly fertile and carbon-rich soils formed through an extant but ancient soil management system. The objective of this study was to characterize the organic matter accumulated in AfDE and contrast it with non-AfDE soils. Characterization of bulk soil organic matter of several (n=11) AfDE and non-AfDE pairs of surface (0-15 cm) soils using thermal analysis techniques (TG-DSC-EGA) resulted in substantial differences in SOM composition and the presence of pyrogenic C. Such pyrogenic organic matter is generally considered recalcitrant, but the fertility gains in AfDE are generated by labile, more rapidly cycling pools of SOM. As a result, we characterized hot water- and pyrophosphate-extractable pools of SOM using fluorescence (EEM/PARAFAC) and high resolution mass spectrometry (FT-ICR-MS). EEM/PARAFAC data suggests that AfDE samples had a greater fraction of their DOM that was more humic-like than the paired non-AfDE samples. Similarly, FT-ICR-MS analyses of extracts suggest that differences among the sites analyzed were larger than between the paired AfDE and non-AfDE extracts. Overall, in spite of substantial differences in the composition of bulk SOM, the extractable fractions appear to be relatively similar between the AfDE and non-AfDE soils.

  9. MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia

    PubMed Central

    Dou, Liping; Li, Jingxin; Zheng, Dehua; Li, Yonghui; Gao, Xiaoning; Xu, Chengwang; Gao, Li; Wang, Lili; Yu, Li

    2013-01-01

    Myeloid/lymphoid or mixed-lineage AF4 acute lymphoblastic leukemia (MLL-AF4 ALL) is a pediatric leukemia that occurs rarely in adults. MLL-AF4 ALL is typically characterized by the presence of chromosomal translocation (t(4;1l)(q21;q23)), leading to expression of MLL-AF4 fusion protein. Although MLL-AF4 fusion protein triggers a molecular pathogenesis and hematological presentations that are unique to leukemias, the precise role of this oncogene in leukemogenesis remains unclear. Previous studies have indicated that microRNAs (miRs) might modulate the expression of MLL-AF4 ALL fusion protein, thereby suggesting the involvement of miR in progression or suppression of MLL-AF4 ALL. We have previously demonstrated that miR-205 negatively regulates transcription of an MLL-AF4 luciferase reporter. Here, we report that exogenous expression of miR-205 in MLL-AF4 human cell lines (RS4;11 and MV4-11) inversely regulates the expression of MLL-AF4 at both messenger RNA (mRNA) and protein level. Furthermore, miR-205 significantly induced apoptosis in MLL-AF4 cells as evidenced by Annex in V staining using fluorescence-activated cell sorting (FACS) analysis. The proliferative capacity of leukemic cells was suppressed by miR-205. The addition of an miR-205 inhibitor was able to restore the observed effects. In conclusion, these findings demonstrate that miR-205 may have potential value as a novel therapeutic agent in the treatment of MLL-AF4 ALL. PMID:24009426

  10. Structure and biological activities of eumenine mastoparan-AF (EMP-AF), a new mast cell degranulating peptide in the venom of the solitary wasp (Anterhynchium flavomarginatum micado).

    PubMed

    Konno, K; Hisada, M; Naoki, H; Itagaki, Y; Kawai, N; Miwa, A; Yasuhara, T; Morimoto, Y; Nakata, Y

    2000-11-01

    A new mast cell degranulating peptide, eumenine mastoparan-AF (EMP-AF), was isolated from the venom of the solitary wasp Anterhynchium flavomarginatum micado, the most common eumenine wasp found in Japan. The structure was analyzed by FAB-MS/MS together with Edman degradation, which was corroborated by solid-phase synthesis. The sequence of EMP-AF, Ile-Asn-Leu-Leu-Lys-Ile-Ala-Lys-Gly-Ile-Ile-Lys-Ser-Leu-NH(2), was similar to that of mastoparan, a mast cell degranulating peptide from a hornet venom; tetradecapeptide with C-terminus amidated and rich in hydrophobic and basic amino acids. In fact, EMP-AF exhibited similar activity to mastoparan in stimulating degranulation from rat peritoneal mast cells and RBL-2H3 cells. It also showed significant hemolytic activity in human erythrocytes. Therefore, this is the first example that a mast cell degranulating peptide is found in the solitary wasp venom. Besides the degranulation and hemolytic activity, EMP-AF also affects on neuromuscular transmission in the lobster walking leg preparation. Three analogs EMP-AF-1 approximately 3 were snythesized and biologically tested together with EMP-AF, resulting in the importance of the C-terminal amide structure for biological activities.

  11. NMR study of the AF-SC-SC-AF phased transition in a pnictide superconductor LaFeAsO1-xHx

    NASA Astrophysics Data System (ADS)

    Fujiwara, Naoki; Sakurai, Ryosuke; Iimura, Soushi; Matsuishi, Satoru; Hosono, Hideo; Yamakawa, Youichi; Kontani, Hiroshi

    2014-03-01

    We have performed 75As and 1H NMR measurements in LaFeAsO1xHx, an isomorphic compound of LaFeAsO1xFx. LaFeAsO1xHx is an electron doped system, and O2- can be replaced with H- up to x = 0.5. LaFeAsO1xHx is known for having double superconducting (SC) domes on H doping. Recently, we discovered that a new antiferromagnetic (AF) phase follows the double SC domes on further H doping, forming a symmetric AF-SC-SC-AF phase alignment in the electronic phase diagram Unlike the AF ordering in the lightly H-doped regime, the AF ordering in the highly H-doped regime is attributed to the nesting between electron pockets. In the conference, we will show the data of both NMR spectra and the relaxation rate 1/T1 in the whole doping region. We will discuss the difference of electronic states between the lightly H-doped AF-SC phases and highly H-doped SC-AF phases. This work is supported by a Grant-in-Aid (Grant No. KAKENHI 23340101) from the Ministry of Education, Science, and Culture, Japan.

  12. Identification and characterization of the afsR homologue regulatory gene from Streptomyces peucetius ATCC 27952.

    PubMed

    Parajuli, Niranjan; Viet, Hung Trinh; Ishida, Kenji; Tong, Hang Thi; Lee, Hei Chan; Liou, Kwangkyoung; Sohng, Jae Kyung

    2005-01-01

    We have isolated an afsR homologue, called afsR-p, through genome analysis of Streptomyces peucetius ATCC 27952. AfsR-p shares 60% sequence identity with AfsR from Streptomyces coelicolor A3 (2). afsR-p was expressed under the control of the ermE* promoter in its hosts S. peucetius, Streptomyces lividans TK 24, Streptomyces clavuligerus and Streptomyces griseus. We observed overproduction of doxorubicin (4-fold) in S. peucetius, gamma-actinorhodin (2.6-fold) in S. lividans, clavulanic acid (1.5-fold) in S. clavuligerus and streptomycin (slight) in S. griseus. Overproduction was due to expression of the gene in these strains as compared to the wild-type strains harboring the vector only. Comparative study of the expression of afsR-p revealed that regulatory networking in Streptomyces is not uniform. We speculate that phosphorylated AfsR-p becomes bound to the promoter region of afsS. The latter activates other regulatory genes, including pathway regulatory genes, and induces the production of secondary metabolites including antibiotics. We identified specific conserved amino acids and exploited them for the isolation of the partial sequence of the afsR homologue from S. clavuligerus and Streptomyces achromogens (rubradirin producer). Such findings provide additional evidence for the presence of a serine/threonine and tyrosine kinase-dependent global regulatory network in Streptomyces.

  13. Identification and characterization of the afsR homologue regulatory gene from Streptomyces peucetius ATCC 27952.

    PubMed

    Parajuli, Niranjan; Viet, Hung Trinh; Ishida, Kenji; Tong, Hang Thi; Lee, Hei Chan; Liou, Kwangkyoung; Sohng, Jae Kyung

    2005-01-01

    We have isolated an afsR homologue, called afsR-p, through genome analysis of Streptomyces peucetius ATCC 27952. AfsR-p shares 60% sequence identity with AfsR from Streptomyces coelicolor A3 (2). afsR-p was expressed under the control of the ermE* promoter in its hosts S. peucetius, Streptomyces lividans TK 24, Streptomyces clavuligerus and Streptomyces griseus. We observed overproduction of doxorubicin (4-fold) in S. peucetius, gamma-actinorhodin (2.6-fold) in S. lividans, clavulanic acid (1.5-fold) in S. clavuligerus and streptomycin (slight) in S. griseus. Overproduction was due to expression of the gene in these strains as compared to the wild-type strains harboring the vector only. Comparative study of the expression of afsR-p revealed that regulatory networking in Streptomyces is not uniform. We speculate that phosphorylated AfsR-p becomes bound to the promoter region of afsS. The latter activates other regulatory genes, including pathway regulatory genes, and induces the production of secondary metabolites including antibiotics. We identified specific conserved amino acids and exploited them for the isolation of the partial sequence of the afsR homologue from S. clavuligerus and Streptomyces achromogens (rubradirin producer). Such findings provide additional evidence for the presence of a serine/threonine and tyrosine kinase-dependent global regulatory network in Streptomyces. PMID:15921897

  14. AFS men and women differ most in their lifestyle choices

    USGS Publications Warehouse

    Connelly, N.A.; Brown, T.L.; Hardiman, J.M.

    2006-01-01

    The American Fisheries Society sponsored a survey to examine the career development choices of men and women and how they might differ by gender. A random sample of 700 men and 700 women was selected from the AFS membership database. The survey was mailed out in October 2004 and 991 questionnaires were returned for an adjusted response rate of 71%. Some differences exist between men and women in the areas of interest development, education, and employment, but the substantive differences occur in lifestyle choices. Women with a fisheries career are less likely to be married than men, even when age is controlled for, and women who are married are more likely to have dual-career considerations than their male counterparts. Among respondents without dependents in their home during their professional career, twice as many women as men think having children will adversely affect their career. For those with dependents, more than twice as many women as men said they had to put their career "on hold" because of their dependents. While AFS members do not represent all members of the fisheries profession, their experiences shed substantial light on the lifestyle choices likely faced by most members of the profession.

  15. Reading levels of Spanish deaf students.

    PubMed

    Torres Monreal, Santiago; Santana Hernández, Rafael

    2005-01-01

    THE READING LEVELS of a population of 93 Spanish deaf students were examined. All study participants had prelingual profound hearing loss; their ages ranged from 9 to 20 years. All were enrolled in compulsory education during 2002-2003 in the Canary Islands (Spain). They were evaluated with sentence and text comprehension subtests from the Evaluation of Reading Processes of Primary Education Students, whose Spanish acronym is PROLEC (Cuetos, Rodríguez, & Ruano, 1996). A questionnaire on reading attitude was also used (Espín, 1987). Study results were consistent with those of previous research: Deaf students, at the end of their primary school education (mean age 13 years), have reading levels similar to or lower than the reading levels of hearing students at the onset of primary school education (mean age 7 years). These deaf students also have an indifferent attitude toward reading.

  16. Ten years of the Spanish Virtual Observatory

    NASA Astrophysics Data System (ADS)

    Solano, E.

    2015-05-01

    The main objective of the Virtual Observatory (VO) is to guarantee an easy and efficient access and analysis of the information hosted in astronomical archives. The Spanish Virtual Observatory (SVO) is a project that was born in 2004 with the goal of promoting and coordinating the VO-related activities at national level. SVO is also the national contact point for the international VO initiatives, in particular the International Virtual Observatory Alliance (IVOA) and the Euro-VO project. The project, led by Centro de Astrobiología (INTA-CSIC), is structured around four major topics: a) VO compliance of astronomical archives, b) VO-science, c) VO- and data mining-tools, and d) Education and outreach. In this paper I will describe the most important results obtained by the Spanish Virtual Observatory in its first ten years of life as well as the future lines of work.

  17. SPANISH PEAKS WILDERNESS STUDY AREA, COLORADO.

    USGS Publications Warehouse

    Budding, Karin E.; Kluender, Steven E.

    1984-01-01

    A geologic and geochemical investigation and a survey of mines and prospects were conducted to evaluate the mineral-resource potential of the Spanish Peaks Wilderness Study Area, Huerfano and Las Animas Counties, in south-central Colorado. Anomalous gold, silver, copper, lead, and zinc concentrations in rocks and in stream sediments from drainage basins in the vicinity of the old mines and prospects on West Spanish Peak indicate a substantiated mineral-resource potential for base and precious metals in the area surrounding this peak; however, the mineralized veins are sparse, small in size, and generally low in grade. There is a possibility that coal may underlie the study area, but it would be at great depth and it is unlikely that it would have survived the intense igneous activity in the area. There is little likelihood for the occurrence of oil and gas because of the lack of structural traps and the igneous activity.

  18. Exploratory analysis of Spanish energetic mining accidents.

    PubMed

    Sanmiquel, Lluís; Freijo, Modesto; Rossell, Josep M

    2012-01-01

    Using data on work accidents and annual mining statistics, the paper studies work-related accidents in the Spanish energetic mining sector in 1999-2008. The following 3 parameters are considered: age, experience and size of the mine (in number of workers) where the accident took place. The main objective of this paper is to show the relationship between different accident indicators: risk index (as an expression of the incidence), average duration index for the age and size of the mine variables (as a measure of the seriousness of an accident), and the gravity index for the various sizes of mines (which measures the seriousness of an accident, too). The conclusions of this study could be useful to develop suitable prevention policies that would contribute towards a decrease in work-related accidents in the Spanish energetic mining industry. PMID:22721539

  19. Early comprehension of the Spanish plural*

    PubMed Central

    Arias-Trejo, Natalia; Cantrell, Lisa M.; Smith, Linda B.; Alva Canto, Elda A.

    2015-01-01

    Understanding how linguistic cues map to the environment is crucial for early language comprehension and may provide a way for bootstrapping and learning words. Research has suggested that learning how plural syntax maps to the perceptual environment may show a trajectory in which children first learn surrounding cues (verbs, modifiers) before a full mastery of the noun morpheme alone. The Spanish plural system of simple codas, dominated by one allomorph -s, and with redundant agreement markers, may facilitate early understanding of how plural linguistic cues map to novel referents. Two-year-old Mexican children correctly identified multiple novel object referents when multiple verbal cues in a phrase indicated plurality as well as in instances when the noun morphology in novel nouns was the ONLY indicator of plurality. These results demonstrate Spanish-speaking children’s ability to use plural noun inflectional morphology to infer novel word referents which may have implications for their word learning. PMID:24560441

  20. Presentational Focus in Heritage and Monolingual Spanish

    ERIC Educational Resources Information Center

    Hoot, Bradley

    2012-01-01

    In Spanish, it is most commonly claimed that constituents in narrow presentational focus appear rightmost, where they also get main stress (1a), while stress in situ (1b) is infelicitous. (1) [Context: Who bought a car?]. a. Compró un carro mi [mamá][subscript F]. bought a car my mom. b. Mi [mamá ][subscript F] compró un carro. However, some…

  1. Automation under suspicion--case flight AF-447 Air France.

    PubMed

    Martins, Edgard; Soares, Marcelo

    2012-01-01

    The probes allow the pilot to control the aircraft speed was essential to the balance of the flight. Opinions of experts who claim that "the design of the plane would have exercised a not inconsiderable role in the occurrence of a disaster." These messages revealed a series of important operating errors in a zone of turbulence, "making the plane uncontrollable, leading to a rapid depressurization device, according to these reports. A lawsuit in Toulouse and in Brazil aims to recognition of the liability of Air France and Airbus not insignificant role in the design and operation of the aircraft in the event of catastrophe. Opinions are taken from senior pilots that no commercial aviation training for certain situations abnormal flight that, if realized, could have influenced the pilots of the AF-447 to remove the plane's fatal dive show what experiments performed in simulators for military pilots, who are permanently subject to critical flight situations.

  2. Installation-restoration program. Records search, Newark AFS, Ohio

    SciTech Connect

    Not Available

    1985-04-01

    Since 1962, many hazardous and potentially hazardous wastes have been generated by industrial operations in Building 4 at Newark AFS. Dirty freon is recycled through a recovery still inside the building and reused. A beryllium dust collection system is located on the east side of Building 4. The collected dust is encapsulated in cement and sent off-station for disposal. Twelve hazardous materials storage or staging areas were identified. During interviews, it was determined that large quantities of dirty freon had been dumped along the entire perimeter fence line and in particular two specific locations. An additional spill site was located in the area at the north-east corner of Building 4 near the location of the virgin freon tanks. An unknown amount of spent battery acid and spent solvents were spilled in this area between 1962 and 1964.

  3. [HG-AFS determination of selenium in Moringa oleifera].

    PubMed

    Huang, Guo-qing; Xiao, Zi-jun

    2007-02-01

    The Se content in Moringa oleifera was studied by hydride generation atom fluorescence spectrometry (HG-AFS) with wet digestion. The effects of the way of digestion, the work condition of apparatus, the reaction medium and acidity, and the reducing agent and masking agent on the determination of Se were investigated. And the operating condition of apparatus was optimized. The results showed that the detection limit of Se in this method was 0.42 ng x mL(-1) in the linear ranger of 0-120 ng x mL(-1), the relative standard deviation was 3.53% (n = 11), and the recovery of the method was 95.2%-104.6%. It was showed that the method was very sensitive, simple, rapid and accurate.

  4. Optimised secure transmission through untrusted AF relays using link adaptation

    NASA Astrophysics Data System (ADS)

    Taki, Mehrdad; Sadeghi, Mohammad

    2016-05-01

    A new transmission scheme is presented for a two-hop relay network including two AF relays, considering physical layer security where relays are not able to detect signal with an acceptable bit error rate (BER) but the combined received signal is detected with an acceptable BER at the final receiver. It is assumed that there is no direct path between the transmitter and the receiver (relay network without diversity). Adaptive modulation and coding is utilised at the transmitter and transmission powers of the transmitter and of the relays are continuously adapted provisioning individual average power constraint for each node. Numerical evaluations show that an acceptable performance degradation is seen by the proposed secure relaying scheme compared to the optimum relay selection scheme without security constraint.

  5. Dietary guidelines for the Spanish population.

    PubMed

    Aranceta, J; Serra-Majem, L

    2001-12-01

    Therapeutic properties have been attributed to the diet since ancient times. Epidemiological evidence starting in the early 1960s supports the relationship between different dietary components, dietary balance and the development of risk factors for prevalent chronic diseases in Western societies. There is also evidence supporting the protective effect of other components of the diet and lifestyle, like regular physical activity. During the last two years, groups of Spanish experts in the field of food, nutrition and health sciences have been involved in the process of analysing each food group in Spanish food patterns under a standard format. For each food group, current level of consumption, trends and scientific evidence linking each particular group or its components with patterns of disease, risk factors or protective effects have been determined from a public health perspective. Conclusions and recommendations for each food group, agreed under consensus by the Spanish Society of Community Nutrition (SENC) collaborative group of experts, are summarised and reflected in the Food Guide Pyramid presented in this paper. PMID:11918490

  6. Entrepreneurial Orientation Scale: Adaptation to Spanish.

    PubMed

    Boada-Grau, Joan; Sánchez-García, José Carlos; Viardot, Eric; Boada-Cuerva, Maria; Vigil-Colet, Andreu

    2016-01-01

    Entrepreneurship is linked to the perception of opportunities, to orientation, to attitudes, to the fear of failure and to entrepreneurial motivations. Entrepreneurial orientation is a fundamental construct for understanding the phenomenon of entrepreneurship. What is more, it is multidimensional and has attracted considerable attention from researchers in recent years. The objective of this study was to adapt the original 12-item English scale to Spanish and to analyze its psychometric properties. The participants in the present study were 925 Spanish employees (48.2% men, 51.5% women, M age = 42.49 years, SD age = 11.25) from the Autonomous Communities of Catalonia and Castilla-León. After applying an ESEM (RMSEA = .06; CFI = .97 and TLI = .95) a structure was determined made up of four factors which corroborated the structure of the original scale: Autonomy (α = .71 and CI = .68 - .73), Innovativeness (α = .70 and CI = .67 - .73), Risk Taking (α = .72 and CI = .68 - .74) and Competitive Aggressiveness (α = .70 and CI = .67 - .73). The four factors displayed suitable reliability. The study also found evidences of validity in relation to a series of external correlates and various scales which refer to workaholism, irritation and burnout. The scale presented here may prove useful for satisfactorily identifying, in Spanish, the entrepreneurial orientation of the working population. PMID:27453429

  7. Bioethics in Mediterranean culture: the Spanish experience.

    PubMed

    Busquets, Ester; Roman, Begoña; Terribas, Núria

    2012-11-01

    This article presents a view of bioethics in the Spanish context. We may identify several features common to Mediterranean countries because of their relatively similar social organisation. Each country has its own distinguishing features but we would point two aspects which are of particular interest: the Mediterranean view of autonomy and the importance of Catholicism in Mediterranean culture. The Spanish experience on bioethics field has been marked by these elements, trying to build a civic ethics alternative, with the law as an important support. So, Spanish bioethics has been developed in two parallel levels: in the academic and policy maker field (University and Parliament) and in clinical practice (hospitals and healthcare ethics committees), with different paces and methods. One of the most important changes in the paternalistic mentality has been promoted through the recognition by law of the patient's rights and also through the new generation of citizens, clearly aware on the exercise of autonomy. Now, the healthcare professionals have a new challenge: adapt their practice to this new paradigm.

  8. Evaluation of the atoxigenic Aspergillus flavus strain AF36 in pistachio orchards

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The atoxigenic strain Aspergillus flavus AF36, which has been extensively used as a biocontrol agent in commercial corn and cotton fields to reduce aflatoxin contamination, was applied in research pistachio orchards from 2002 to 2005 and in commercial pistachio orchards from 2008 to 2011. AF36 was a...

  9. 32 CFR 989.12 - AF Form 813, Request for Environmental Impact Analysis.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the issues to potential environmental impacts. AF Form 813 must be retained with the EA or EIS to record the focusing of environmental issues. ... 32 National Defense 6 2014-07-01 2014-07-01 false AF Form 813, Request for Environmental...

  10. 32 CFR 989.12 - AF Form 813, Request for Environmental Impact Analysis.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the issues to potential environmental impacts. AF Form 813 must be retained with the EA or EIS to record the focusing of environmental issues. ... 32 National Defense 6 2013-07-01 2013-07-01 false AF Form 813, Request for Environmental...

  11. 32 CFR 989.12 - AF Form 813, Request for Environmental Impact Analysis.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the issues to potential environmental impacts. AF Form 813 must be retained with the EA or EIS to record the focusing of environmental issues. ... 32 National Defense 6 2010-07-01 2010-07-01 false AF Form 813, Request for Environmental...

  12. 32 CFR 989.12 - AF Form 813, Request for Environmental Impact Analysis.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the issues to potential environmental impacts. AF Form 813 must be retained with the EA or EIS to record the focusing of environmental issues. ... 32 National Defense 6 2012-07-01 2012-07-01 false AF Form 813, Request for Environmental...

  13. 32 CFR 989.12 - AF Form 813, Request for Environmental Impact Analysis.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the issues to potential environmental impacts. AF Form 813 must be retained with the EA or EIS to record the focusing of environmental issues. ... 32 National Defense 6 2011-07-01 2011-07-01 false AF Form 813, Request for Environmental...

  14. AF Therapy Now and in the Future: Drugs, Biologicals, and Ablation

    PubMed Central

    Woods, Christopher E.; Olgin, Jeffrey

    2014-01-01

    Rationale Atrial fibrillation (AF) is a complex disease with multiple interrelating causes culminating in rapid, seemingly disorganized atrial activation. Therapy targeting AF is rapidly changing and improving. Objective The purpose of this review is to summarize current state-of-the-art diagnostic and therapeutic modalities for treatment of atrial fibrillation. The review focuses on reviewing treatment as it relates to the pathophysiological basis of disease and reviews pre-clinical and clinical evidence for potential new diagnostic and therapeutic modalities, including imaging, biomarkers, pharmacologic therapy as well as ablative strategies for AF. Conclusions Current ablation and drug therapy approaches to treating AF are largely based on treating the arrhythmia once the substrate occurs and is more effective in paroxysmal AF rather than persistent or permanent AF. However, there is much research aimed at prevention strategies, targeting AF substrate—so called upstream therapy. Improved diagnostics, using imaging, genetics and biomarkers are needed to better identify sub-types of AF based on underlying substrate/mechanism to allow more directed therapeutic approaches. In addition, novel anti-arrhythmics with more atrial specific effects may reduce limiting pro-arrhythmic side-effects. Advances in ablation therapy are aimed at improving technology to reduce procedure time and in mechanism targeted approaches. PMID:24763469

  15. Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.

    PubMed

    Sun, Ting Ting; Wang, Yan; Cheng, Hong; Xiao, Hu Zhang; Xiang, Juan Juan; Zhang, Jie Ting; Yu, Siu Bun Sydney; Martin, Tracey Amanda; Ye, Lin; Tsang, Lai Ling; Jiang, Wen Guo; Xiaohua, Jiang; Chan, Hsiao Chang

    2014-03-01

    How mutations or dysfunction of CFTR may increase the risk of malignancies in various tissues remains an open question. Here we report the interaction between CFTR and an adherens junction molecule, AF-6/afadin, and its involvement in the development of colon cancer. We have found that CFTR and AF-6/afadin are co-localized at the cell-cell contacts and physically interact with each other in colon cancer cell lines. Knockdown of CFTR results in reduced epithelial tightness and enhanced malignancies, with increased degradation and reduced stability of AF-6/afadin protein. The enhanced invasive phenotype of CFTR-knockdown cells can be completely reversed by either AF-6/afadin over-expression or ERK inhibitor, indicating the involvement of AF-6/MAPK pathway. More interestingly, the expression levels of CFTR and AF-6/afadin are significantly downregulated in human colon cancer tissues and lower expression of CFTR and/or AF-6/afadin is correlated with poor prognosis of colon cancer patients. The present study has revealed a previously unrecognized interaction between CFTR and AF-6/afadin that is involved in the pathogenesis of colon cancer and indicated the potential of the two as novel markers of metastasis and prognostic predictors for human colon cancer.

  16. Attitudes and Representations of Spanish and the Spread of the Language Industries in Brazil

    ERIC Educational Resources Information Center

    Bugel, Talia; Santos, Helade Scutti

    2010-01-01

    This paper analyzes the context of Spanish language teaching in Brazil. We examine the representations of and attitudes toward Rioplatense/Argentinean Spanish and Peninsular Spanish--and toward the speakers of each of these varieties--held by Brazilian learners of Spanish as a foreign language. To provide the context in which Spanish learning…

  17. Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

    PubMed Central

    Shirai, Cara Lunn; Ley, James N.; White, Brian S.; Kim, Sanghyun; Tibbitts, Justin; Shao, Jin; Ndonwi, Matthew; Wadugu, Brian; Duncavage, Eric J.; Okeyo-Owuor, Theresa; Liu, Tuoen; Griffith, Malachi; McGrath, Sean; Magrini, Vincent; Fulton, Robert S.; Fronick, Catrina; O’Laughlin, Michelle; Graubert, Timothy A.; Walter, Matthew J.

    2015-01-01

    SUMMARY Heterozygous somatic mutations in the spliceosome gene U2AF1 occur in ~11% of patients with myelodysplastic syndromes (MDS), the most common adult myeloid malignancy. It is unclear how these mutations contribute to disease. We examined in vivo hematopoietic consequences of the most common U2AF1 mutation using a doxycycline-inducible transgenic mouse model. Mice expressing mutant U2AF1(S34F) display altered hematopoiesis and changes in pre-mRNA splicing in hematopoietic progenitor cells by whole transcriptome analysis (RNA-seq). Integration with human RNA-seq datasets determined that common mutant U2AF1-induced splicing alterations are enriched in RNA processing genes, ribosomal genes, and recurrently-mutated MDS and acute myeloid leukemia-associated genes. These findings support the hypothesis that mutant U2AF1 alters downstream gene isoform expression, thereby contributing to abnormal hematopoiesis in MDS patients. PMID:25965570

  18. Accuracy of Computer-Generated, Spanish-Language Medicine Labels

    PubMed Central

    Sharif, Iman; Tse, Julia

    2011-01-01

    OBJECTIVE We evaluated the accuracy of translated, Spanish-language medicine labels among pharmacies in a borough with a large Spanish-speaking population. METHODS A cross-sectional, telephone survey of all pharmacies in the Bronx, New York, was performed. Selected pharmacies were visited to learn about the computer software being used to generate Spanish medicine labels. Outcomes included the proportion of pharmacies providing Spanish medicine labels, frequency of computerized translation, and description of Spanish medicine labels produced. RESULTS Of 316 pharmacies, 286 (91%) participated. Overall, 209 (73%) provided medicine labels in Spanish. Independent pharmacies were significantly more likely to provide Spanish labels than were hospital or chain pharmacies (88% vs 57% vs 32%; P < .0001). Pharmacies that provided Spanish labels mostly commonly (86%) used computer programs to do so; 11% used lay staff members, and 3% used a professional interpreter. We identified 14 different computer programs used to generate Spanish labels, with 70% of pharmacies using 1 of 3 major programs. We evaluated 76 medicine labels generated by 13 different computer programs. Overall, 32 Spanish labels (43%) included incomplete translations (a mixture of English and Spanish), and 6 additional labels contained misspellings or grammar errors, which resulted in an overall error rate of 50%. CONCLUSIONS Although pharmacies were likely to provide medicine labels translated into Spanish, the quality of the translations was inconsistent and potentially hazardous. Unless regulations and funding support the technological advances needed to ensure the safety of such labeling, we risk perpetuating health disparities for populations with limited English proficiency. PMID:20368321

  19. The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function.

    PubMed

    Jensen, Thomas; Elster, Lisbeth; Nielsen, Søren Møller; Poda, Suresh Babu; Loechel, Frosty; Volbracht, Christiane; Klewe, Ib Vestergaard; David, Laurent; Watson, Stephen P

    2014-11-15

    The identification of the novel and selective GPR3 inverse agonist AF64394, the first small molecule inhibitor of GPR3 receptor function, is described. Structure activity relationships and syntheses based around AF64394 are reported.

  20. Usage frequencies of complement-taking verbs in Spanish and English: data from Spanish monolinguals and Spanish-English bilinguals.

    PubMed

    Dussias, Paola E; Marful, Alejandra; Gerfen, Chip; Bajo Molina, María Teresa

    2010-11-01

    Verb bias, or the tendency of a verb to appear with a certain type of complement, has been employed in psycholinguistic literature as a tool to test competing models of sentence processing. To date, the vast majority of sentence processing research involving verb bias has been conducted almost exclusively with monolingual speakers, and predominantly with monolingual English speakers, despite the fact that most of the world's population is bilingual. To test the generality of competing theories of sentence comprehension, it is important to conduct cross-linguistic studies of sentence processing and to add bilingual data to theories of sentence comprehension. Given this, it is critical for the field to develop verb bias estimates from monolingual speakers of languages other than English and from bilingual populations. We begin to address these issues in two norming studies. Study 1 provides verb bias norming data for 135 Spanish verbs. A second aim of Study 1 was to determine whether verb bias estimates remain stable over time. In Study 2, we asked whether Spanish-English speakers are able to learn verb-specific information, such as verb bias, in their second language. The answer to this question is critical to conducting studies that examine when, during the course of sentence comprehension, bilingual speakers exploit verb information specific to the second language. To facilitate cross-linguistic work, we compared our verb bias results with those provided by monolingual English speakers in a previous norming study conducted by Garnsey, Lotocky, Pearlmutter, and Myers (1997). Our Spanish data demonstrated that individual verbs showed significant similarities in their verb bias across the 3 years of data collection. We also show that bilinguals are able to learn the biases of verbs in their second language, even when immersed in the first language environment. Appendixes A-C, containing the bilingual norms discussed in the article, may be downloaded from http://brm.psychonomic-journals.org/content/supplemental.

  1. La Hispanidad en los Estados Unidos (Spanish Influence in the United States)

    ERIC Educational Resources Information Center

    Da Silva, Zenia Sacks

    1975-01-01

    This paper recounts a brief history of Spanish exploration in the territory of the United States and surveys Spanish influence in industry, agriculture, foods, architecture and vocabulary. (Text is in Spanish.) (CK)

  2. Professional Development of Teachers--A Prerequisite for AfL to Be Successfully Implemented in the Classroom

    ERIC Educational Resources Information Center

    Smith, Kari

    2011-01-01

    A prerequisite for AfL to be successfully implemented in the classroom is the teachers' assessment practice. In many contexts, including the Norwegian, AfL has not been successfully dealt with during initial teacher education, and there is a need for qualified teachers to engage in professional development in AfL. This article first discusses…

  3. Critical behavior of a triangular lattice Ising AF/FM bilayer

    NASA Astrophysics Data System (ADS)

    Žukovič, M.; Bobák, A.

    2016-03-01

    We study a bilayer Ising spin system consisting of antiferromagnetic (AF) and ferromagnetic (FM) triangular planes, coupled by ferromagnetic exchange interaction, by standard Monte Carlo and parallel tempering methods. The AF/FM bilayer is found to display the critical behavior completely different from both the single FM and AF constituents as well as the FM/FM and AF/AF bilayers. Namely, by finite-size scaling (FSS) analysis we identify at the same temperature a standard Ising transition from the paramagnetic to FM state in the FM plane that induces a ferrimagnetic state with a finite net magnetic moment in the AF plane. At lower temperatures there is another phase transition, that takes place only in the AF plane, to different ferrimagnetic state with spins on two sublattices pointing parallel and on one sublattice antiparallel to the spins on the FM plane. FSS indicates that the corresponding critical exponents are close to the two-dimensional three-state ferromagnetic Potts model values.

  4. Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

    PubMed Central

    Przychodzen, Bartlomiej; Jerez, Andres; Guinta, Kathryn; Sekeres, Mikkael A.; Padgett, Richard; Maciejewski, Jaroslaw P.

    2013-01-01

    Recently, recurrent mutations of spliceosomal genes were frequently identified in myeloid malignancies, as well as other types of cancers. One of these spliceosomal genes, U2AF1, was affected by canonical somatic mutations in aggressive type of myeloid malignancies. We hypothesized that U2AF1 mutations causes defects of splicing (missplicing) in specific genes and that such misspliced genes might be important in leukemogenesis. We analyzed RNA deep sequencing to compare splicing patterns of 201 837 exons between the cases with U2AF1 mutations (n = 6) and wild type (n = 14). We identified different alternative splicing patterns in 35 genes comparing cells with mutant and wild-type U2AF1. U2AF1 mutations are associated with abnormal splicing of genes involved in functionally important pathways, such as cell cycle progression and RNA processing. In addition, many of these genes are somatically mutated or deleted in various cancers. Of note is that the alternative splicing patterns associated with U2AF1 mutations were associated with specific sequence signals at the affected splice sites. These novel observations support the hypothesis that U2AF1 mutations play a significant role in myeloid leukemogenesis due to selective missplicing of tumor-associated genes. PMID:23775717

  5. Spanish Peaks, Sangre de Cristo Range, Colorado

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Spanish Peaks, on the eastern flank of the Sangre de Cristo range, abruptly rise 7,000 feet above the western Great Plains. Settlers, treasure hunters, trappers, gold and silver miners have long sighted on these prominent landmarks along the Taos branch of the Santa Fe trail. Well before the westward migration, the mountains figured in the legends and history of the Ute, Apache, Comanche, and earlier tribes. 'Las Cumbres Espanolas' are also mentioned in chronicles of exploration by Spaniards including Ulibarri in 1706 and later by de Anza, who eventually founded San Francisco (California). This exceptional view (STS108-720-32), captured by the crew of Space Shuttle mission STS108, portrays the Spanish Peaks in the context of the southern Rocky Mountains. Uplift of the Sangre de Cristo began about 75 million years ago and produced the long north-trending ridges of faulted and folded rock to the west of the paired peaks. After uplift had ceased (26 to 22 million years ago), the large masses of igneous rock (granite, granodiorite, syenodiorite) that form the Peaks were emplaced (Penn, 1995-2001). East and West Spanish Peaks are 'stocks'-bodies of molten rock that intruded sedimentary layers, cooled and solidified, and were later exposed by erosion. East Peak (E), at 12,708 ft is almost circular and is about 5 1/2 miles long by 3 miles wide, while West Peak (W), at 13,623 ft is roughly 2 3/4 miles long by 1 3/4 miles wide. Great dikes-long stone walls-radiate outward from the mountains like spokes of a wheel, a prominent one forms a broad arc northeast of East Spanish Peak. As the molten rock rose, it forced its way into vertical cracks and joints in the sedimentary strata; the less resistant material was then eroded away, leaving walls of hard rock from 1 foot to 100 feet wide, up to 100 feet high, and as long as 14 miles. Dikes trending almost east-west are also common in the region. For more information visit: Sangres.com: The Spanish Peaks (accessed January 16

  6. I [image omitted] Spanish: K-8 Attitudes toward Learning Spanish with Computers

    ERIC Educational Resources Information Center

    Garcia-Villada, Eduardo

    2011-01-01

    This study investigates children's attitudes and technology use for learning Spanish, and examines the type of technology-enhanced learning activities they enjoy. A survey with two versions was developed to gather attitudes and opinions of 2,220 children in grades K-2 and 3-8 in eight small rural school districts in the Midwest of the United…

  7. Developing English and Spanish Literacy in a One-Way Spanish Immersion Program

    ERIC Educational Resources Information Center

    Hollingsworth, Lindsay Kay

    2013-01-01

    This quantitative, causal-comparative study examined the possible cause and effect relationship between educational programming, specifically one-way Spanish immersion and traditional English-only, and native English-speaking fifth graders' vocabulary and reading comprehension. Archival data was used to examine students' reading achievement as…

  8. Spanish Language Materials for the Spanish Speaker: An Overview of the State of the Art.

    ERIC Educational Resources Information Center

    Clarkson, William M.

    The field of Spanish language instruction for bilingual Chicanos has been an area of pedagogical neglect within most college and university language departments. In the past, teachers wishing to implement a significant modification in their approach and methodology found the task virtually impossible because of a scarcity of commercially prepared…

  9. SCDC Spanish Curricula Units. Spanish SL Strand, Unit 10, Grade 3, Supplement & Ditto Packet.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Support materials for the last of 40 instructional kits of the Spanish as a Second Language Strand for primary grades are contained in this supplement to Unit 10 developed for third graders. A teacher's guide for this unit, consisting of kits 37-40, gives the timetable for use of materials. These instructional aids are designed to help the teacher…

  10. SCDC Spanish Curricula Units. Spanish SL, Unit 5, Grade 2, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    The Spanish SL strand of unit five for second graders provides the English-dominant child with the structures and vocabulary he will need for effective communication in a bilingual environment. This teacher's guide contains assessment activities, activities for oral language development, and activities for listening and related skills of…

  11. SCDC Spanish Curricula Units. Spanish SL Strand, Unit 3, Grade One, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Using the school as a theme, unit three of the Spanish as a Second Language curriculum for first graders focuses on learning and assessment activities designed to provide the English-dominant child with structures and vocabulary needed for effective communication in a bilingual environment. Activities in kits 9-12 help build concepts in a new…

  12. Cuentos y fabulas (Stories and Fables), Spanish-S: 7509.13.

    ERIC Educational Resources Information Center

    Suarez, Maria S.

    This course offers students the opportunity to read and listen to 19th and 20th century Spanish short stories as well as moral, literary, and satirical fables of different epochs. (Several of the fables are included.) The student is thus exposed to new vocabulary and to the literary form of the short story. The authors represented here belong to…

  13. SCDC Spanish Curricula Units. Spanish SL Strand, Unit 10, Grade 3, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Communities around the world is the theme of unit 10 of the Spanish as a Second Language Strand for grade three. Learning and assessment activities are designed to provide the English-dominant child with structures and vocabulary for effective communication in a bilingual environment. The language arts, math, and science activities help the…

  14. Intermediate SCDC Spanish Curricula Units. Spanish SL, Unit 1, Kits 1-4, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Focusing on the community, this Spanish as a Second Language unit provides the English-dominant child with the structures and vocabulary needed for effective communication in a bilingual environment. The instructional and assessment activities help the child build concepts in his new language through formal and informal language experiences.…

  15. Intermediate SCDC Spanish Curricula Units. Spanish SL, Unit 1, Kits 1-4, Supplement & Ditto Packet.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Designed for use with the teacher's guide to the Spanish as a Second Language unit, this supplement and ditto packet includes visual aids and worksheets to help the teacher carry out the instructional and assessment activities. The illustrations are designed to help stimulate oral language and conceptual development. These visual materials…

  16. SCDC Spanish Curricula Units. Spanish SL Strand, Unit 8, Grade 3, Supplement & Ditto Packet.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Supplementary instructional aids and two small pupil readers for unit eight of the Spanish as a Second Language strand developed for grade three are designed for use with the teacher's guide. Illustrations and worksheets for kits 29-32 are to help the teacher carry out learning and assessment activities which will provide the English-dominant…

  17. Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF

    PubMed Central

    DeVore, Adam D.; Hellkamp, Anne S.; Becker, Richard C.; Berkowitz, Scott D.; Breithardt, Guenter; Hacke, Werner; Halperin, Jonathan L.; Hankey, Graeme J.; Mahaffey, Kenneth W.; Nessel, Christopher C.; Singer, Daniel E.; Fox, Keith A. A.; Patel, Manesh R.; Piccini, Jonathan P.

    2016-01-01

    Aims The high costs associated with treatment for atrial fibrillation (AF) are primarily due to hospital care, but there are limited data to understand the reasons for and predictors of hospitalization in patients with AF. Methods and results The ROCKET AF trial compared rivaroxaban with warfarin for stroke prophylaxis in AF. We described the frequency of and reasons for hospitalization during study follow-up and utilized Cox proportional hazards models to assess for baseline characteristics associated with all-cause hospitalization. Of 14 171 patients, 14% were hospitalized at least once. Of 2614 total hospitalizations, 41% were cardiovascular including 4% for AF; of the remaining, 12% were for bleeding. Compared with patients not hospitalized, hospitalized patients were older (74 vs. 72 years), and more frequently had diabetes (46 vs. 39%), prior MI (23 vs. 16%), and paroxysmal AF (19 vs. 17%), but less frequently had prior transient ischaemic attack/stroke (49 vs. 56%). After multivariable adjustment, lung disease [hazard ratio (HR) 1.46, 95% confidence interval (CI) 1.29–1.66], diabetes [1.22, (1.11–1.34)], prior MI [1.27, (1.13–1.42)], and renal dysfunction [HR 1.07 per 5 unit GFR < 65 mL/min, (1.04–1.10)] were associated with increased hospitalization risk. Treatment assignment was not associated with differential rates of hospitalization. Conclusion Nearly 1 in 7 of the moderate-to-high-risk patients with AF enrolled in this trial was hospitalized within 2 years, and both AF and bleeding were rare causes of hospitalization. Further research is needed to determine whether care pathways directed at comorbid conditions among AF patients could reduce the need for and costs associated with hospitalization. PMID:27174904

  18. Husbandry of Spanish ribbed newts (Pleurodeles waltl).

    PubMed

    Joven, Alberto; Kirkham, Matthew; Simon, András

    2015-01-01

    Research on urodele amphibians, such as newts, is constantly contributing to our understanding of fundamental biological processes. In the present chapter, we present detailed husbandry protocols for the Spanish ribbed newt (Pleurodeles waltl ). We describe the main phases of their life cycle, with emphasis on the progressive development of sensory, motor, and integration systems, which lead to the acquisition of specific stereotyped (and conditioned) behaviors. The methods are outlined to manage housing, feeding, handling, captive breeding, health monitoring, and euthanasia in this species under laboratory conditions. With minor changes, these protocols can also be applied to other species of urodele amphibians commonly used in laboratory research.

  19. Breaking the Silence at Spanish Universities

    PubMed Central

    Valls, Rosa; Puigvert, Lídia; Melgar, Patricia; Garcia-Yeste, Carme

    2016-01-01

    The first research conducted on violence against women in the university context in Spain reveals that 62% of the students know of or have experienced situations of this kind within the university institutions, but only 13% identify these situations in the first place. Two main interrelated aspects arise from the data analysis: not identifying and acknowledging violent situations, and the lack of reporting them. Policies and actions developed by Spanish universities need to be grounded in two goals: intransigence toward any kind of violence against women, and bystander intervention, support, and solidarity with the victims and with the people supporting the victims. PMID:26825116

  20. The Inhibition of Inflammasome by Brazilian Propolis (EPP-AF)

    PubMed Central

    Hori, Juliana I.; Zamboni, Dario S.; Carrão, Daniel B.; Goldman, Gustavo Henrique; Berretta, Andresa A.

    2013-01-01

    Propolis extracts have gained the attention of consumers and researchers due to their unique chemical compositions and functional properties such as its anti-inflammatory activity. Recently, it was described a complex that is also important in inflammatory processes, named inflammasome. The inflammasomes are a large molecular platform formed in the cell cytosol in response to stress signals, toxins, and microbial infections. Once activated, the inflammasome induces caspase-1, which in turn induces the processing of inflammatory cytokines such as IL-1β and IL-18. So, to understand inflammasomes regulation becomes crucial to treat several disorders including autoinflammatory diseases. Since green propolis extracts are able to regulate inflammatory pathways, this work purpose was to investigate if this extract could also act on inflammasomes regulation. First, the extract was characterized and it demonstrated the presence of important compounds, especially Artepillin C. This extract was effective in reducing the IL-1β secretion in mouse macrophages and this reduction was correlated with a decrease in activation of the protease caspase-1. Furthermore, we found that the extract at a concentration of 30 μg/mL was not toxic to the cells even after a 18-hour treatment. Altogether, these data indicate that Brazilian green propolis (EPP-AF) extract has a role in regulating the inflammasomes. PMID:23690844

  1. Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi.

    PubMed

    Bourjot, Mélanie; Leyssen, Pieter; Eydoux, Cécilia; Guillemot, Jean-Claude; Canard, Bruno; Rasoanaivo, Philippe; Guéritte, Françoise; Litaudon, Marc

    2012-04-27

    In an effort to identify novel inhibitors of chikungunya (CHIKV) and dengue (DENV) virus replication, a systematic study with 820 ethyl acetate extracts of madagascan plants was performed in a virus-cell-based assay for CHIKV, and a DENV NS5 RNA-dependent RNA polymerase (RdRp) assay. The extract obtained from the stem bark of Flacourtia ramontchi was selected for its significant activity in both assays. Six new phenolic glycosides, named flacourtosides A-F (1-6), phenolic glycosides itoside H, xylosmin, scolochinenoside D, and poliothrysoside, and betulinic acid 3β-caffeate were obtained using the bioassay-guided isolation process. Their structures were elucidated by comprehensive analyses of NMR spectroscopic and mass spectrometric data. Even though several extracts and fractions showed significant selective antiviral activity in the CHIKV virus-cell-based assay, none of the purified compounds did. However, in the DENV RNA polymerase assay, significant inhibition was observed with betulinic acid 3β-caffeate (IC(50) = 0.85 ± 0.1 μM) and to a lesser extent for the flacourtosides A and E (1 and 5, respectively), and scolochinenoside D (IC(50) values ~10 μM). PMID:22439591

  2. Spanish for Agricultural Purposes: Another Use of Video.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.; And Others

    Spanish for Agricultural Purposes is a set of study materials designed to furnish experience in Spanish for North American agriculturalists preparing to work in Latin America. The materials were developed in the University of Illinois' Language Learning Laboratory (LLL). They consist of (1) a basic manual based on specimens of agricultural writing…

  3. Tracing Mexican Spanish /s/: A Cross-Section of History.

    ERIC Educational Resources Information Center

    Lipski, John M.

    1994-01-01

    Examines linguistic data from peripheral areas of Mexico and suggests that the contemporary resistance of the final /s/ in Spanish is characteristic only of urban regions. The study also hypothesizes that Spanish final /s/ was once more generally weakened throughout Mexico. An indirect Nahuatl contribution is also postulated. (62 references)…

  4. Chicano Spanish: Cross Hispanic Language Attitudes toward Specific Lexical Items.

    ERIC Educational Resources Information Center

    Giron, Robert LeRoy

    A study was undertaken to gather attitudes of Spanish-speakers toward specific types of Chicano Spanish dialect lexical items. Reactions were randomly taken from 11 Latin American students who attended Southern Illinois University at Carbondale during the 1975 spring semester; 20 Mexican residents of Ciudad Juarez, Mexico, who attended English as…

  5. Overview of Spanish and Latin American Distance Higher Education.

    ERIC Educational Resources Information Center

    Garcia Garrido, Jose Luis

    1991-01-01

    Provides a brief overview of Spanish and Latin American distance education programs for higher education and describes the three most important institutions: (1) the Spanish UNED (Universidad Nacional de Educacion a Distancia); (2) the Costa Rican UNED (Universidad Estatal a Distancia); and (3) the Venezuelan UNA (Universidad Nacional Abierta).…

  6. Which Features of Spanish Learners' Pronunciation Most Impact Listener Evaluations?

    ERIC Educational Resources Information Center

    McBride, Kara

    2015-01-01

    This study explores which features of Spanish as a foreign language (SFL) pronunciation most impact raters' evaluations. Native Spanish speakers (NSSs) from regions with different pronunciation norms were polled: 147 evaluators from northern Mexico and 99 evaluators from central Argentina. These evaluations were contrasted with ratings from…

  7. Descubriendo La Lectura: An Application of Reading Recovery in Spanish.

    ERIC Educational Resources Information Center

    Escamilla, Kathy; Andrade, Anna

    1992-01-01

    Research suggests that use of a child's native language in initial literacy instruction is beneficial. The Descubriendo la Lectura (DLL) Spanish-language application of the English Reading Recovery Program is described as implemented for one Spanish-speaking first grade boy. The DLL program capitalizes on strengths children demonstrate in reading.…

  8. Stress-Timing, Spanish Rhythm, and Particle Phonology.

    ERIC Educational Resources Information Center

    Uber, Diane Ringer

    Data was collected from 45-minute conversational interviews of 20 Cubans, who arrived in the United States in 1980, to analyze vocalic processes in Cuban Spanish. Four vocalic processes found in Cuban Spanish (raising and devoicing of unstressed vowels, lengthening of stressed vowels, and diphthongization of stressed mid vowels) were examined.…

  9. El Diccionario Del Espanol Chicano (The Dictionary of Chicano Spanish).

    ERIC Educational Resources Information Center

    Galvan, Roberto A.; Teschner, Richard V.

    This is a supplementary dictionary of the Spanish spoken by Chicanos in the states of Texas, California, Arizona, New Mexico, Colorado, and Florida. The nearly 8,000 entries represent a compilation of Chicano words and phrases not typically found in standard dictionaries. Items are listed alphabetically in Spanish, followed by an English…

  10. Encountering Difference: Images of Otherness in Contemporary Spanish Film

    ERIC Educational Resources Information Center

    Smith, Andrea Meador; Campbell, Sarah Cox

    2015-01-01

    Addressing the underrepresentation of films by female directors in Spanish language and culture classes, this work proposes the inclusion of two films, Chus Gutiérrez's "Retorno a Hansala" (2008) and Icíar Bollaín's "También la lluvia" (2010), in the curriculum of advanced or upper-level Spanish courses. Both films expand…

  11. Naming Pseudowords in Spanish: Effects of Syllable Frequency

    ERIC Educational Resources Information Center

    Carreiras, Manuel; Perea, Manuel

    2004-01-01

    Three naming experiments were conducted to examine the role of the first and the second syllable during speech production in Spanish. Facilitative effects of syllable frequency with disyllabic words have been reported in Dutch and Spanish (Levelt & Wheeldon, 1994; Perea & Carreiras, 1998). In both cases, the syllable frequency effect was…

  12. Learning Spanish with "Laura": The Effects of a Pedagogical Agent

    ERIC Educational Resources Information Center

    Theodoridou, Katerina

    2011-01-01

    The purpose of this study was to investigate the effects of an animated pedagogical agent on Spanish vocabulary learning. Furthermore, the study examined learners' reactions and attitudes towards the presence of the pedagogical agent in the web-based environments. A total of 47 university students enrolled in two fourth-semester Spanish classes…

  13. An Overview of Medical Spanish Curricula in the United States

    ERIC Educational Resources Information Center

    Hardin, Karol

    2015-01-01

    The US health care system faces linguistic challenges. Disparities in language-concordant care for Spanish speakers persist due to current demographics and a paucity of bilingual providers. A proliferation of courses in Spanish for health care professions suggests that universities and post-graduate institutions are attempting to meet this need;…

  14. Age of acquisition and allophony in Spanish-English bilinguals.

    PubMed

    Barlow, Jessica A

    2014-01-01

    This study examines age of acquisition (AoA) in Spanish-English bilinguals' phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants' /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker's two languages.

  15. Age of acquisition and allophony in Spanish-English bilinguals

    PubMed Central

    Barlow, Jessica A.

    2014-01-01

    This study examines age of acquisition (AoA) in Spanish-English bilinguals’ phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants’ /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker’s two languages. PMID:24795664

  16. Decreasing Anxiety and Frustration in the Spanish Language Classroom.

    ERIC Educational Resources Information Center

    Haskin, Joanna; Smith, Maria de Lourdes Hernandez; Racine, Margaret

    This report describes instructional strategies to decrease anxiety and frustration in the Spanish classroom. Participants were five 7th grade Spanish classes in two suburban middle schools. Student interventions included a study skills guide; partner and group presentations, skits, and activities; and group oral reading. Teacher interventions…

  17. Age of acquisition and allophony in Spanish-English bilinguals.

    PubMed

    Barlow, Jessica A

    2014-01-01

    This study examines age of acquisition (AoA) in Spanish-English bilinguals' phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants' /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker's two languages. PMID:24795664

  18. Clitic Placement in Spanish-English Bilingual Children

    ERIC Educational Resources Information Center

    Perez-Leroux, Ana Teresa; Cuza, Alejandro; Thomas, Danielle

    2011-01-01

    Can transfer occur in child bilingual syntax when surface overlap does not involve the syntax-pragmatics interface? Twenty-three Spanish/English bilingual children participated in an elicited imitation study of clitic placement in Spanish restructuring contexts, where variable word order is not associated with pragmatic or semantic factors.…

  19. Deaf Lives: Nineteenth-Century Spanish Deaf Girls and Women

    ERIC Educational Resources Information Center

    Plann, Susan

    2007-01-01

    This article is about the lives of nineteenth-century Spanish deaf girls and women. The research presented is contained in a larger work, a book titled "Portraits from the Spanish National Deaf-Mute School," to be published by Gallaudet University Press. These "portraits" are in fact biographical essays on nineteenth-century deaf people and their…

  20. 16 CFR 455.5 - Spanish language sales.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Spanish language sales. 455.5 Section 455.5 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.5 Spanish language sales. Link to an amendment published at 77 FR 73914, Dec. 12, 2012. If...

  1. El Espanol como Idioma Universal (Spanish as a Universal Language)

    ERIC Educational Resources Information Center

    Mijares, Jose

    1977-01-01

    A proposal to transform Spanish into a universal language because it possesses the prerequisites: it is a living language, spoken in several countries; it is a natural language; and it uses the ordinary alphabet. Details on simplification and standardization are given. (Text is in Spanish.) (AMH)

  2. Vocabulary and Sentence Structure in Emergent Spanish Literacy

    ERIC Educational Resources Information Center

    Briceño, Allison

    2016-01-01

    Dual language and bilingual education programs are increasing in number and popularity across the country. However, little information is available on how to teach children to read and write in Spanish. This article explores some of the similarities and differences in vocabulary and sentence structure in Spanish and English and considers the…

  3. Spanish Second Language Acquisition: State of the Science.

    ERIC Educational Resources Information Center

    Lafford, Barbara A., Ed.; Salaberry, Rafael, Ed.

    This collection of papers provides an overview of previous studies on the acquisition of Spanish as a second or foreign language, theoretical approaches used in these studies, and effects of various pedagogical approaches on the development of Spanish interlanguage systems. The 10 chapters include the following: (1) "Phonology: Staking Out the…

  4. Spanish Partial Immersion Program. 1987-1988 Evaluation Report.

    ERIC Educational Resources Information Center

    Leitner, David

    First year planning and implementation of the Portland (Oregon) Partial Immersion Program in Spanish--an elementary magnet program providing a total language experience in a multi-cultural setting--were assessed. The program uses both Spanish and English to instruct students; half of the instructional day is conducted in each language. The…

  5. Spanish-Surname Farm Operators in Southern Texas.

    ERIC Educational Resources Information Center

    Economic Research Service (USDA), Washington, DC.

    The Economic Research Service has used 1964 census data to develop information on the characteristics of Spanish-surname farmers in 14 Texas counties. Selected characteristics were examined for this population and for non-Spanish-surnamed farm operators in the same counties. It was found, for example, that Mexican American farm-operator families…

  6. Historical Perspectives on Spanish-Quechua Language Contact in Peru.

    ERIC Educational Resources Information Center

    Klee, Carol A.

    2001-01-01

    Presents an overview of language policy in Peru from colonial times to the present and analyzes the impact of this policy, together with the underlying social conditions, on Spanish-Quechua language contact and Spanish language change in present-day Peru. (Author/VWL)

  7. Food Service Technical Terms. English-Spanish Lexicon.

    ERIC Educational Resources Information Center

    Shin, Masako T.

    This English-Spanish lexicon presents food service technical terms. The terms are divided into seven categories: basic food items, common baking terms, food cutting terms, general cooking terms, non-English culinary terms, and tools and equipment. Each English word or term is followed by its Spanish equivalent(s). (YLB)

  8. Spanish Validation of the Spence Children's Anxiety Scale

    ERIC Educational Resources Information Center

    Orgiles, Mireia; Mendez, Xavier; Spence, Susan H.; Huedo-Medina, Tania B.; Espada, Jose P.

    2012-01-01

    The purpose of this study was to investigate the factorial structure and psychometric properties of the Spence Children's Anxiety Scale (SCAS) in a sample of 1,708 Spanish children aged between 8 and 12 years. The SCAS was demonstrated to have satisfactory internal consistency with the Spanish sample, and factor analysis confirmed the six-factor…

  9. Individualized Spanish Materials: A First-Year College Program.

    ERIC Educational Resources Information Center

    Hendrickson, James M.

    This course was developed at Lansing Community College in order to allow students to study beginning Spanish at their individual learning rate. The materials consist of an orientation packet, student record sheets, quarter-term syllabi, tape lists, and nineteen lesson packets for Elementary Spanish. The materials were designed to accompany…

  10. El Cuidado de Ninos. (Child Care). Spanish-English Wordbook.

    ERIC Educational Resources Information Center

    Mintz, Adin

    This wordbook was developed as a supplementary aid for both native Spanish speakers learning English and the English speaking who are learning Spanish. It contains definitions of selected words important to a particular trade or occupation--in this case, child care. The English spelling of the word defined is in parentheses above the Spanish…

  11. Instructional Materials in Spanish for Agriculture. Final Report.

    ERIC Educational Resources Information Center

    Mainous, Bruce H.

    A federally funded project to develop Spanish for Agricultural Purposes, a set of instructional materials for agricultural specialists planning to work in Latin America, is reported. The materials are intended for use by individuals with at least a year's college-level study of Spanish. They include: a series of authentic readings, each with an…

  12. The Nature of Spanish versus English Language Use at Home

    ERIC Educational Resources Information Center

    Branum-Martin, Lee; Mehta, Paras D.; Carlson, Coleen D.; Francis, David J.; Goldenberg, Claude

    2014-01-01

    Home language experiences are important for children's development of language and literacy. However, the home language context is complex, especially for Spanish-speaking children in the United States. A child's use of Spanish or English likely ranges along a continuum, influenced by preferences of particular people involved, such as parents,…

  13. Fundamental Laws of the State: The Spanish Constitution.

    ERIC Educational Resources Information Center

    Ministerio de Informacion y Turismo, Madrid (Spain).

    This political document is introduced by the head of the Spanish State, His Excellency Don Francisco Franco Bahamonde in a speech given on 22 November 1966 to the session of the Spanish Cores. The speech outlines in general terms the political and philosophical ideals of His Excellency. The Constitution is presented in several sections including:…

  14. Validity of the Spanish version of the Emotional Labour Scale.

    PubMed

    Picardo, Juan M; López-Fernández, Consuelo; Hervás, María José Abellán

    2014-06-01

    In this article we address concerns raised by Brumit and Glenn (2013) regarding the validity of the Spanish version of the Emotional Labour Scale (ELS). We respond to requests in relation to the translated version of the scale and the eigenvalue series. We also give an explanation of the differences in results between the original version and the Spanish version of the scale.

  15. Language Sample Analysis in Spanish-Speaking Children: Methodological Considerations.

    ERIC Educational Resources Information Center

    Gutierrez-Clellen, Vera F.; Restrepo, M. Adelaida; Bedore, Lisa; Pena, Elizabeth; Anderson, Raquel

    2000-01-01

    This article discusses issues related to selection and development of language assessment procedures for children who speak Spanish and English based on spontaneous language samples and shows how available procedures can be applied to research and clinical aims with these children. Sociolinguistic influences in Spanish-speaker language performance…

  16. Article Use in Spanish-Speaking Children with SLI.

    ERIC Educational Resources Information Center

    Restrepo, Maria Adelaida; Gutierrez-Clellen, Vera F.

    2001-01-01

    Analyzed article use in Spanish-speaking children with specific language impairment who are learning English as a Second Language. The surface hypothesis account of specific language impairment was evaluated in relation to the use of articles in these children. Language samples were obtained from 15 Spanish-speaking children with language…

  17. Factors Influencing the Second Language Acquisition of Spanish Vibrants

    ERIC Educational Resources Information Center

    Hurtado, Luz Marcela; Estrada, Chelsea

    2010-01-01

    This article examines the role of linguistic and sociolinguistic factors in the second language (L2) acquisition of Spanish vibrants. The data consist of 2 sets of recordings from 37 students enrolled in a Spanish pronunciation class. The statistical program VarbRul was used to analyze 7,597 samples. The vibration (simple or multiple) and the…

  18. Gifted Spanish Speaking English Learners' Participation in Advanced Placement Programs

    ERIC Educational Resources Information Center

    Torres, Luz Adriana

    2010-01-01

    This qualitative study sought to uncover the contextual factors of the schooling process that affect the enrollment of gifted Spanish speaking English Learners (ELs) in Advanced Placement (AP) courses. In addition, this study investigated the perceptions of gifted Spanish speaking ELs toward AP courses and how these perceptions might affect their…

  19. U.S. Spanish and Education: Global and Local Intersections

    ERIC Educational Resources Information Center

    García, Ofelia

    2014-01-01

    The author of this chapter argues that the failure of Spanish language education policies in the United States to educate both Latinos and non-Latinos has to do with the clash between three positions--(a) the English language, characterized by U.S. educational authorities as the unique and powerful lingua franca; (b) the Spanish language, as…

  20. Phonological Acquisition in Bilingual Spanish-English Speaking Children

    ERIC Educational Resources Information Center

    Fabiano-Smith, Leah; Goldstein, Brian A.

    2010-01-01

    Purpose: In this study, the authors aimed to determine how between-language interaction contributes to phonological acquisition in bilingual Spanish-English speaking children. Method: A total of 24 typically developing children, ages 3;0 (years;months) to 4;0, were included in this study: 8 bilingual Spanish-English speaking children, 8…

  1. 34. View of the Women's lounge (Spanish room) looking northwest. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. View of the Women's lounge (Spanish room) looking northwest. A Mural by Merlin Hardy depicts a "Spanish dance theme in a 19th century setting." (removed 1997) - Fort Ord, Soldiers' Club, California State Highway 1 near Eighth Street, Seaside, Monterey County, CA

  2. From "Pinocho" to "Papa Noel": Recent Children's Books in Spanish.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2002-01-01

    Provides a list of recently published books in Spanish for children and adolescents. A tentative grade level is indicated for each book, but it is suggested that the individual child's Spanish-reading ability, interest, taste, and purpose should be the main criteria for determining the true level of each book. (Author/VWL)

  3. Collections and Services for the Spanish-Speaking: Accessibility.

    ERIC Educational Resources Information Center

    Marquis, Solina Kasten

    2003-01-01

    Discusses making public library collections accessible to Spanish-speaking users and describes the consequences that can result from inattention to linguistic and cultural accessibility. Topics include cataloging issues and solutions; labeling; shelving; signage; electronic access; Spanish language training for staff; intercultural communication;…

  4. On the Syllabification of /tl/ Clusters in Spanish.

    ERIC Educational Resources Information Center

    Parker, Steve

    A study investigated the correct syllabification of intervocalic /tl/ consonant clusters in Spanish dialects that lack word-initial /tl/, using data from Peruvian Spanish. The study attempted to discover native speaker preference through the playing of a popular game involving, in part, dividing a word into syllables. Words containing the /tl/…

  5. Dual Role Interpreters: Spanish Teachers in New Latino Communities

    ERIC Educational Resources Information Center

    Colomer, Soria Elizabeth

    2010-01-01

    This article is based on a qualitative study documenting how Spanish teachers, as some of the few Spanish-speaking educators in new Latino diaspora communities, bear an especially heavy burden as dual role interpreters and unofficial school representatives. Drawing from the semistructured interview data of twenty-six north Georgia educators, I…

  6. Spanish/English Speech Practices: Bringing Chaos to Order

    ERIC Educational Resources Information Center

    Toribio, Almeida Jacqueline

    2004-01-01

    This paper presents a linguistic analysis of Spanish-English bilingual speech for scholars and practitioners of bilingualism. More specifically, the study surveys several outcomes of language contact, among these, inter-lingual transference, codeswitching, and convergence, as evidenced in the speech practices of heritage Spanish speakers in the…

  7. Driving: English-Spanish. Enlarged and Revised Edition.

    ERIC Educational Resources Information Center

    Grosse, Philip

    The bilingual glossary, in English-to-Spanish, defines words and phrases related to driving and traffic safety. It is intended for individuals driving in Mexico and other Spanish-speaking countries. A second section lists the vocabulary used in common road signs, and the third section lists useful phrases for communicating about car repair needs.…

  8. Hybrid Spanish Programs: A Challenging and Successful Endeavor

    ERIC Educational Resources Information Center

    Hermosilla, Luis

    2014-01-01

    Several types of hybrid Spanish programs have been developed in US colleges and universities for more than ten years, but the most common structure consists of a course in which the instruction combines face-to-face time with an instructor and the use of an online platform. Studies have demonstrated that a well-developed hybrid Spanish program can…

  9. The Linguistic Similarities of Spanish Heritage and Second Language Learners

    ERIC Educational Resources Information Center

    Lynch, Andrew

    2008-01-01

    This article addresses the situation of lower-proficiency heritage language learners of Spanish in terms of their linguistic similarities to second language learners. The analysis highlights grammatical and lexical features in the oral discourse of Spanish heritage and second language learners at intermediate and advanced levels of study,…

  10. The Semantics of the Spanish Conditional in Discourse.

    ERIC Educational Resources Information Center

    Lozano, Anthony G.

    1988-01-01

    Contrasts the hypothetical conditional or "modo potencial" in Spanish with the subsequence conditional. Passages from "El habla de la ciudad de Mexico" and from works by Carballido and Borges are cited as examples. Other grammatical studies of the Spanish conditional are reviewed. (LMO)

  11. The Spanish Imperative and Deontic Utterances in Literary Passages.

    ERIC Educational Resources Information Center

    Lozano, Anthony G.

    1990-01-01

    Examines the Spanish imperative paradigm and Ramsey's notion that all forms of Spanish imperatives are substituted by subjunctives in the first and third person. The concept of deontic modality in demonstrating the relationships among imperative and imperativelike patterns that carry the meaning of obligation, permission, and prohibition is also…

  12. Instructional Resources and Materials for Business-Spanish Courses.

    ERIC Educational Resources Information Center

    Cere, Ronald

    The program, curriculum, and materials needed to provide business Spanish training are described, and the available instructional materials are reviewed and listed. In developing a business Spanish program, decisions must be made regarding goals, content, structure, instructional format, evaluation procedures, and target population. The content of…

  13. Foreign Language Experience in the Elementary School: Spanish.

    ERIC Educational Resources Information Center

    Anne Arundel County Public Schools, Annapolis, MD.

    Guidelines for teaching Spanish in the elementary school are presented. The program is designed to develop the skills of careful listening and accurate pronunciation and to provide pleasurable learning experiences through dialogues, songs, and games. Spanish is contrasted with English to relate the language experience to other aspects of the…

  14. Teaching Reading in Spanish: A Study of Teacher Effectiveness.

    ERIC Educational Resources Information Center

    Ramirez, Arnulfo G.

    The effect of teaching behaviors on student reading achievement in Spanish was investigated. A group of 18 teachers of Spanish reading and their classes were observed across two reading lessons having similar content. Each lesson was presented in two twenty-minute segments, thus allowing for four videotaping sessions. Students were pre- and…

  15. Spanish as a Heritage Language Assessment: Successes, Failures, Lessons Learned

    ERIC Educational Resources Information Center

    MacGregor-Mendoza, Patricia

    2012-01-01

    From its origins over three decades ago, interest in the field of Spanish as a heritage language (SHL) has grown and has produced a wealth of research. While our understanding of the sociolinguistic profile of Spanish heritage language learners has increased and we have advanced in our knowledge of the linguistic abilities and strategies Spanish…

  16. Developing a course to teach Spanish for health care professionals.

    PubMed

    Bloom, Melanie; Timmerman, Gayle M; Sands, Dolores

    2006-07-01

    To make the baccalaureate nursing curriculum more responsive to changing U.S. demographics, the School of Nursing at The University of Texas at Austin instituted a required course, titled Spanish for Health Care Professionals. This course, developed in collaboration with the University's Department of Spanish and Portuguese, focuses on conversational Spanish using the communicative language teaching approach, rather than grammar and medical terminology instruction. Class activities, along with course materials, are linked to nursing practice. Course assignments are designed to develop authentic communication in reading, writing, listening, speaking, and understanding culture, and students demonstrated oral and written linguistic gains in relation to their Spanish fluency and accuracy. Because the Hispanic population is now the largest minority group in the United States, this course will help nurses communicate with Spanish-speaking patients.

  17. Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription.

    PubMed

    Santos-Beneit, Fernando; Rodríguez-García, Antonio; Sola-Landa, Alberto; Martín, Juan F

    2009-04-01

    The regulatory proteins AfsR and PhoP control expression of the biosynthesis of actinorhodin and undecylprodigiosin in Streptomyces coelicolor. Electrophoretic mobility shift assays showed that PhoP(DBD) does not bind directly to the actII-ORF4, redD and atrA promoters, but it binds to the afsS promoter, in a region overlapping with the AfsR operator. DNase I footprinting studies revealed a PhoP protected region of 26 nt (PHO box; two direct repeats of 11 nt) that overlaps with the AfsR binding sequence. Binding experiments indicated a competition between AfsR and PhoP; increasing concentrations of PhoP(DBD) resulted in the disappearance of the AfsR-DNA complex. Expression studies using the reporter luxAB gene coupled to afsS promoter showed that PhoP downregulates afsS expression probably by a competition with the AfsR activator. Interestingly, AfsR binds to other PhoP-regulated promoters including those of pstS (a component of the phosphate transport system) and phoRP (encoding the two component system itself). Analysis of the AfsR-protected sequences in each of these promoters allowed us to distinguish the AfsR binding sequence from the overlapping PHO box. The reciprocal regulation of the phoRP promoter by AfsR and of afsS by PhoP suggests a fine interplay of these regulators on the control of secondary metabolism.

  18. Stewardship of the Spanish national health system.

    PubMed

    Bankauskaite, Vaida; Novinskey, Christina M

    2010-01-01

    Along with resource generation, financing, and health service delivery, stewardship is a key health system function. However, very little empirical analysis has been carried out on it. This paper aims to fill this gap in the literature by assessing the Ministry of Health's (MoHs) role as a steward of the Spanish National Health System (NHS) after the 2001 decentralization reform of health care management to the Autonomous Communities. We use the following stewardship framework with six sub-functions for the analysis, looking at the MoH's ability to: (1) formulate strategic policy framework; 2) ensure a fit between policy objectives and organizational structure and culture; (3) ensure tools for implementation; (4) build coalitions and partnerships; (5) generate intelligence, and (6) ensure accountability. We describe the stewardship function, identify existing challenges and issues in the Spanish case, and reflect upon methodological aspects of this exercise. We use reports, documents, articles, and official statistics to complete the analysis. Overall, we find the MoH to give an average performance in its role as the steward of the health system. The MoH has progressed particularly well in generating intelligence as well as formulating a strategic policy framework over recent years. However, it lacks the appropriate authority to efficiently coordinate the health system and to ensure that the Autonomous Communities implement policies that are in-line with overall NHS objectives.

  19. The Spanish contribution to the CTA Observatory

    NASA Astrophysics Data System (ADS)

    Barrio, J. A.; CTA Consortium

    2015-05-01

    The Cherenkov Telescope Array (CTA) project is an initiative to build the next generation ground- based Very High Energy gamma-ray instrument. It will serve as an open observatory to a wide astrophysics community and will provide a deep insight into the non-thermal high-energy universe. To achieve such goals, it will offer full-sky coverage (with Northern and Southern hemisphere sites), an improvement in sensitivity by about an order of magnitude, an enlarged span in energy (from a few tens of GeV to above 100 TeV), and enhanced angular and energy resolutions over existing VHE gamma-ray observatories. An international collaboration has formed with more than 1100 members from 28 countries all over the world. The Spanish High Energy Astrophysics community is deeply committed to CTA, with more than 70 scientists and technicians from 9 research groups currently involved in building prototypes for several CTA subsystems. This participation covers a wide list of items, both hardware- and software-related. The former includes telescope-level (camera electronics and mechanics and telescope undercarriage) and observatory- level (array optical calibration and atmospheric monitoring) elements. And the latter includes the design of the data pipelines and the scheduling for observational proposals. In this report, the status of the CTA project and the contribution of the Spanish community will be presented.

  20. Stewardship of the Spanish national health system.

    PubMed

    Bankauskaite, Vaida; Novinskey, Christina M

    2010-01-01

    Along with resource generation, financing, and health service delivery, stewardship is a key health system function. However, very little empirical analysis has been carried out on it. This paper aims to fill this gap in the literature by assessing the Ministry of Health's (MoHs) role as a steward of the Spanish National Health System (NHS) after the 2001 decentralization reform of health care management to the Autonomous Communities. We use the following stewardship framework with six sub-functions for the analysis, looking at the MoH's ability to: (1) formulate strategic policy framework; 2) ensure a fit between policy objectives and organizational structure and culture; (3) ensure tools for implementation; (4) build coalitions and partnerships; (5) generate intelligence, and (6) ensure accountability. We describe the stewardship function, identify existing challenges and issues in the Spanish case, and reflect upon methodological aspects of this exercise. We use reports, documents, articles, and official statistics to complete the analysis. Overall, we find the MoH to give an average performance in its role as the steward of the health system. The MoH has progressed particularly well in generating intelligence as well as formulating a strategic policy framework over recent years. However, it lacks the appropriate authority to efficiently coordinate the health system and to ensure that the Autonomous Communities implement policies that are in-line with overall NHS objectives. PMID:21069771

  1. Light Pollution REECL Spanish SQM Network

    NASA Astrophysics Data System (ADS)

    Zamorano, Jaime; Sánchez de Miguel, Alejandro; Nievas, Miguel; Tapia, Carlos; Ocaña, Francisco; Izquierdo, Jaime; Gallego, Jesús; Pascual, Sergio; Colomer, Francisco; Bará, Salvador; Ribas, Salvador; Morales, Ángel; Marco, Enric; Muñoz-Tuñón, Casiana; Solano, Enrique; Alacid, José Manuel; Naves, Ramón; lluis Salto, Josep; García, Faustino; Luque, Sergi; Quejigo, Rubén; Ribas, Julio

    2015-08-01

    There are some networks of SQM photometers that provide measures of the night sky brightness every night. The analysis of the data provided by the photometers allows the researchers to monitor the nightly, monthly and yearly evolution of the NSB and the relationship with light sources of pollution in intensity and distance. The photometers that are measuring in protected areas will alarm the researchers about eventual increasing of light pollution that could affect the environment.Using models of light dispersion on the atmosphere one can determine which light pollution sources are increasing the sky brightness at different places and in which extension. Networks of fixed photometers acquiring data every night are one of the main inputs to test these models. The collaborative effort of many people provides the necessary data to derive scientific results.We present the SQM network of the Spanish Light Pollution Research collaboration (http://guaix.fis.ucm.es/splpr/SQM-REECL) that is growing with the help of amateur astronomers and interested citizens. Data are being archived in the Spanish Virtual Observatory (SVO) using the IAU and IDA community standard data format for light pollution measurements.

  2. Phosphorylation of AfsR by multiple serine/threonine kinases in Streptomyces coelicolor A3(2).

    PubMed

    Sawai, Reiko; Suzuki, Ayano; Takano, Yuji; Lee, Ping-Chin; Horinouchi, Sueharu

    2004-06-01

    AfsK, a protein serine/threonine kinase, autophosphorylates on serine and threonine residues and phosphorylates serine and threonine residues of AfsR, a transcriptional activator for afsS involved in secondary metabolism in Streptomyces coelicolor A3(2). pkaG encoding a 592-amino-acid protein and SCD10.09 (named afsL) encoding a 580-amino-acid protein, both of which encode an AfsK-like protein, were transcribed throughout growth. PkaG with a histidine-tag and the kinase catalytic domain of PkaG, produced in Escherichia coli, autophosphorylated dominantly on threonine and slightly on serine residues. In addition, these proteins phosphorylated AfsR on threonine and serine residues. The catalytic domain of AfsL also autophosphorylated and phosphorylated AfsR, on threonine and serine residues in both cases. AfsR was thus found to be phosphorylated by multiple kinases. Disruption of the chromosomal pkaG gene resulted in slightly reduced production of the pigmented antibiotic actinorhodin. These findings, together with the presence of about 40 AfsK homologues and at least five AfsR homologues in S. coelicolor A3(2), suggest that the regulatory networks via eukaryotic-type protein phosphorylation are more diverse and versatile than we have expected.

  3. Predicting Bilingual Spanish-English Children's Phonological Awareness Abilities from Their Preschool English and Spanish Oral Language

    ERIC Educational Resources Information Center

    Scarpino, Shelley E.; Lawrence, Frank R.; Davison, Megan D.; Hammer, Carol S.

    2011-01-01

    This longitudinal study investigated the relationship between oral language abilities and phonological awareness in 85 typically developing, Spanish-English preschool children (average age in preschool was 3 years, 9 months). Receptive language skills in Spanish and English were assessed in the autumn and spring during the children's 2 years in…

  4. Spanish-English or English-Spanish in California: The Dialectics of Language in a Sociocultural Historical Context

    ERIC Educational Resources Information Center

    Garcia, Sara Soledad

    2008-01-01

    This is an analysis of California history of the shifting of language policies from Spanish to English, as an Official Language The focus is English as an imposed language that from the beginning of schooling policies stifle a process of language acquisition for the majority of Spanish speakers. In 1849 the California Constitution stipulated that…

  5. How Native Do They Sound? An Acoustic Analysis of the Spanish Vowels of Elementary Spanish Immersion Students

    ERIC Educational Resources Information Center

    Menke, Mandy R.

    2015-01-01

    Language immersion students' lexical, syntactic, and pragmatic competencies are well documented, yet their phonological skill has remained relatively unexplored. This study investigates the Spanish vowel productions of a cross-sectional sample of 35 one-way Spanish immersion students. Learner productions were analyzed acoustically and compared to…

  6. The Spanish Language Book Challenge: How Librarians and Distributors Can Work Together To Better Serve Spanish-Language Readers.

    ERIC Educational Resources Information Center

    Kiser, Karin

    2001-01-01

    Discusses challenges facing libraries trying to order Spanish language materials. Highlights include distribution issues, including small stocks, paying in advance, size of print runs, and varying prices; the Guadalajara International Book Fair; online ordering; communication; and a list of Spanish language book distributors that specialize in…

  7. Cuentos de ayer y de hoy (Stories of Yesterday and Today), Spanish-S: 7509.02.

    ERIC Educational Resources Information Center

    Suarez, Maria

    This course is designed to help students improve their oral and written expression as well as their ability to summarize. Stories by Spanish and Spanish American writers are used. Students also have the opportunity to reinforce skills in recognizing the importance of writing as an efficient means of communication, and experience is provided in…

  8. Totally thorascopic surgical ablation of persistent AF and long-standing persistent atrial fibrillation using the "Dallas" lesion set.

    PubMed

    Edgerton, James R; Jackman, Warren M; Mahoney, Cecile; Mack, Michael J

    2009-12-01

    Minimally invasive surgery consisting of bipolar radiofrequency pulmonary vein (PV) isolation and limited ganglionated plexus ablation is effective in eliminating atrial fibrillation (AF) in patients with paroxysmal AF but is less effective in those with persistent AF or long-standing persistent AF. The purpose of this study was examine the results of minimally invasive surgery incorporating an additional set of radiofrequency ablation lines replicating a left-sided Cox maze III procedure. Thirty patients with persistent AF (n = 10) or long-standing persistent AF (n = 20) underwent minimally invasive surgery with an extended lesion set and PV isolation for a minimum follow-up of 6 months. Linear lesions were created at the roof line, at the anterior line, and between the roof line and the left atrial appendage. All patients underwent limited ganglionated plexus ablation and left atrial appendage excision as well as PV isolation verification. Block across the roof and anterior lines was confirmed in 29 (96.6%) of the 30 patients. Follow-up included 2-week event monitoring with auto-trigger in 21 patients, pacemaker interrogation in 8, and ECG in 1 who was in AF and refused longer-term monitoring. No operative mortality or major morbidity occurred. At 6 months, 24 (80%) of the 30 patients were free of AF: 15 (75%) with long-standing persistent AF and 9 (90%) with persistent AF. Among the six failures, burden of AF was low: one had 1 episode >15 seconds, two had 4 episodes, one had 6 episodes, one had >50 episodes, and one had AF on ECG and refused further monitoring. Early results of minimally invasive surgery with a new extended linear lesion set suggest increased efficacy over PV isolation and limited ganglionated plexus ablation in patients with persistent AF or long-standing persistent AF. PMID:19959146

  9. Effects of a novel cholinergic M1 agonist, AF102B, on ambulation and water drinking behavior in rats.

    PubMed

    Togashi, H; Matsumoto, M; Yoshioka, M; Saito, Y; Saito, H

    1991-01-01

    Effects of a novel M1 agonist, AF102B (cis-2-methylspiro(1,3-oxathiolane-5,3')quinuclidine HCl), on ambulation and water drinking behavior were examined using an Ambulo-Drinkometer. AF64A-treated rats, an animal model for senile dementia of the Alzheimer type (SDAT), and non-treated control rats were used. AF102B was administered orally via tap water at a concentration of 0.01% and 0.1% for an experimental therapeutic dose and a supramaximal dose, respectively. Four-week administration of 0.01% AF102B did not affect either ambulatory activity or water drinking activity in non-treated rats. Successive 0.1% AF102B administration for 4 weeks produced a significant decrease in drinking activity as compared with non-treated control rats. In AF64A-treated rats, AF102B did not change the cholinotoxin AF64A-induced high activity in ambulation. However, a decrease in water drinking activity was observed after 0.1% AF102B administration, as in non-treated rats. These results suggest that therapeutic dose of AF102B do not produce any changes in the spontaneous moter activity and water drinking behavior in normal rats or the animal model for SDAT. Several investigators reported that AF102B (FSK-508; cis-2-methylspiro (1,3-oxathiolane-5,3') quinuclidine HCl) had the property of a relatively specific muscarinic agonist of the M1-type This novel M1 agonist, AF102B, also exerted and ameliorating effect on experimental amnesia; in a T-maze, radial-arm maze task and passive avoidance tasks. AF102B improves the cognitive impairment in various animal models for memory disorders including senile dementia of the Alzheimer type (SDAT). Based on these observations, AF102B has been proposed for the treatment of SDAT.(ABSTRACT TRUNCATED AT 250 WORDS)

  10. Performance of Spanish/English bilingual children on a spanish-language neuropsychological battery: preliminary normative data.

    PubMed

    Rosselli, Mónica; Ardila, Alfredo; Navarrete, M Gina; Matute, Esmeralda

    2010-05-01

    Despite a population of close to 40 million Hispanics/Latinos in the USA who have at least some level of Spanish/English bilingualism, there are few neuropsychological tests and norms available for this group, especially when assessing Spanish/English bilingual children. The purpose of the present research was to provide preliminary normative data for a bilingual population on a comprehensive neuropsychological battery developed for Spanish-speaking children (Evaluación Neuropsicológica Infantil). Norms by age are presented on the performance of 108 Spanish/English bilingual children (ages 5-14 years) and are expected to be useful when testing other Spanish/English bilingual children in the USA.

  11. Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116.

    PubMed

    Baratti, C M; Opezzo, J W; Kopf, S R

    1993-07-01

    Post-training administration of the acetylcholine muscarinic M2 presynaptic receptor antagonist AF-DX 116 (0.1-10.0 mg/kg, ip), facilitated 48 h retention, in male Swiss mice, of a one-trial step-through inhibitory avoidance task. The dose-response curve was an inverted U. AF-DX 116 did not increase the retention latencies of mice that had not received a footshock during training. The influence of AF-DX 116 (1 mg/kg, ip) on retention was time-dependent, which suggests that the drug facilitated memory storage. The memory facilitation induced by AF-DX 116 (1 mg/kg, ip) was prevented by atropine (0.5 mg/kg, ip) administered after training, but 10 min prior to AF-DX 116 treatment. In contrast, neither methylatropine (0.5 mg/kg, ip), a peripherally acting muscarinic receptor blocker, nor mecamylamine (5 mg/kg, ip) or hexamethonium (5 mg/kg, ip), two cholinergic nicotinic receptor antagonists, prevented the effects of post-training AF-DX 116 on retention. Low subeffective doses of the central acting anticholinesterase physostigmine (35 micrograms/kg, ip), administered immediately after training, and AF-DX 116 (0.1 mg/kg, ip), given 10 min after training, acted synergistically to improve retention. The effects of AF-DX 116 (0.1 mg/kg, ip) were not influenced by the peripherally acting anticholinesterase neostigmine (35 micrograms/kg, ip). Considered together, these findings suggest that the activation of a muscarinic cholinergic presynaptic inhibitory mechanism, probably by increasing brain acetylcholine release, may modulate the activity of post-training processes involved in memory storage. PMID:8216161

  12. Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116.

    PubMed

    Baratti, C M; Opezzo, J W; Kopf, S R

    1993-07-01

    Post-training administration of the acetylcholine muscarinic M2 presynaptic receptor antagonist AF-DX 116 (0.1-10.0 mg/kg, ip), facilitated 48 h retention, in male Swiss mice, of a one-trial step-through inhibitory avoidance task. The dose-response curve was an inverted U. AF-DX 116 did not increase the retention latencies of mice that had not received a footshock during training. The influence of AF-DX 116 (1 mg/kg, ip) on retention was time-dependent, which suggests that the drug facilitated memory storage. The memory facilitation induced by AF-DX 116 (1 mg/kg, ip) was prevented by atropine (0.5 mg/kg, ip) administered after training, but 10 min prior to AF-DX 116 treatment. In contrast, neither methylatropine (0.5 mg/kg, ip), a peripherally acting muscarinic receptor blocker, nor mecamylamine (5 mg/kg, ip) or hexamethonium (5 mg/kg, ip), two cholinergic nicotinic receptor antagonists, prevented the effects of post-training AF-DX 116 on retention. Low subeffective doses of the central acting anticholinesterase physostigmine (35 micrograms/kg, ip), administered immediately after training, and AF-DX 116 (0.1 mg/kg, ip), given 10 min after training, acted synergistically to improve retention. The effects of AF-DX 116 (0.1 mg/kg, ip) were not influenced by the peripherally acting anticholinesterase neostigmine (35 micrograms/kg, ip). Considered together, these findings suggest that the activation of a muscarinic cholinergic presynaptic inhibitory mechanism, probably by increasing brain acetylcholine release, may modulate the activity of post-training processes involved in memory storage.

  13. Ear Infections - Multiple Languages: MedlinePlus

    MedlinePlus

    ... on this page, please enable JavaScript. French (français) Japanese (日本語) Korean (한국어) Russian (Русский) Somali (af Soomaali) ... moyenne - français (French) Bilingual PDF Health Information Translations Japanese (日本語) Middle Ear Infection 中耳炎 - 日本語 (Japanese) Bilingual ...

  14. Shoulder Injuries and Disorders - Multiple Languages: MedlinePlus

    MedlinePlus

    ... please enable JavaScript. Arabic (العربية) Chinese - Traditional (繁體中文) French (français) Korean (한국어) Russian (Русский) Somali (af Soomaali) ... Institute of Arthritis and Musculoskeletal and Skin Diseases French (français) Active Range of Motion Exercises: Wrists, Elbows, ...

  15. Oxygen tolerance capacity of upflow anaerobic solid-state (UASS) with anaerobic filter (AF) system.

    PubMed

    Meng, Yao; Jost, Carsten; Mumme, Jan; Wang, Kaijun; Linke, Bernd

    2016-07-01

    In order to investigate the oxygen tolerance capacity of upflow anaerobic solid-state (UASS) with anaerobic filter (AF) system, the effect of microaeration on thermophilic anaerobic digestion of maize straw was investigated under batch conditions and in the UASS with AF system. Aeration intensities of 0-431mL O2/gvs were conducted as pretreatment under batch conditions. Aeration pretreatment obviously enhanced anaerobic digestion and an aeration intensity of 431mL O2/gvs increased the methane yield by 82.2%. Aeration intensities of 0-355mL O2/gvs were conducted in the process liquor circulation of the UASS with AF system. Dissolved oxygen (DO) of UASS and AF reactors kept around 1.39±0.27 and 0.99±0.38mg/L, respectively. pH was relatively stable around 7.11±0.04. Volatile fatty acids and soluble chemical oxygen demand concentration in UASS reactor were higher than those in AF reactor. Methane yield of the whole system was almost stable at 85±7mL/gvs as aeration intensity increased step by step. The UASS with AF system showed good oxygen tolerance capacity.

  16. Oxygen tolerance capacity of upflow anaerobic solid-state (UASS) with anaerobic filter (AF) system.

    PubMed

    Meng, Yao; Jost, Carsten; Mumme, Jan; Wang, Kaijun; Linke, Bernd

    2016-07-01

    In order to investigate the oxygen tolerance capacity of upflow anaerobic solid-state (UASS) with anaerobic filter (AF) system, the effect of microaeration on thermophilic anaerobic digestion of maize straw was investigated under batch conditions and in the UASS with AF system. Aeration intensities of 0-431mL O2/gvs were conducted as pretreatment under batch conditions. Aeration pretreatment obviously enhanced anaerobic digestion and an aeration intensity of 431mL O2/gvs increased the methane yield by 82.2%. Aeration intensities of 0-355mL O2/gvs were conducted in the process liquor circulation of the UASS with AF system. Dissolved oxygen (DO) of UASS and AF reactors kept around 1.39±0.27 and 0.99±0.38mg/L, respectively. pH was relatively stable around 7.11±0.04. Volatile fatty acids and soluble chemical oxygen demand concentration in UASS reactor were higher than those in AF reactor. Methane yield of the whole system was almost stable at 85±7mL/gvs as aeration intensity increased step by step. The UASS with AF system showed good oxygen tolerance capacity. PMID:27372134

  17. Spanish Darwinian iconography: Darwin and evolutionism portrayed in Spanish press cartoons.

    PubMed

    Domínguez, Martí; Mateu, Anna

    2013-11-01

    The theory of evolution has played a major role in the press since it was put forward by Charles Darwin in 1859. Its key role in biology and human philosophy is reflected by its presence in press cartoons, sections where the image of social reality is depicted in a more direct and satirical light. Through cartoons, artists have used their ingenuity or wit to portray one of the most controversial scientific figures of the past two centuries. This study examines the views portrayed by Spanish cartoonists about Charles Darwin and evolutionary theory in 2009, the bicentenary of the naturalist's birth and the celebration of 150 years since the publication of On the Origin of Species. These cartoons show how the controversy between Darwinism and religion remain latent in the heart of Spanish society, and how the figure of Darwin has become one of the main icons of science. PMID:23825239

  18. Spanish Darwinian iconography: Darwin and evolutionism portrayed in Spanish press cartoons.

    PubMed

    Domínguez, Martí; Mateu, Anna

    2013-11-01

    The theory of evolution has played a major role in the press since it was put forward by Charles Darwin in 1859. Its key role in biology and human philosophy is reflected by its presence in press cartoons, sections where the image of social reality is depicted in a more direct and satirical light. Through cartoons, artists have used their ingenuity or wit to portray one of the most controversial scientific figures of the past two centuries. This study examines the views portrayed by Spanish cartoonists about Charles Darwin and evolutionary theory in 2009, the bicentenary of the naturalist's birth and the celebration of 150 years since the publication of On the Origin of Species. These cartoons show how the controversy between Darwinism and religion remain latent in the heart of Spanish society, and how the figure of Darwin has become one of the main icons of science.

  19. Assessment of Alcohol Use Patterns Among Spanish-Speaking Patients

    PubMed Central

    Lotfipour, Shahram; Cisneros, Victor; Anderson, Craig L.; Roumani, Samer; Hoonpongsimanont, Wirachin; Weiss, Jie; Chakravarthy, Bharath; Dykzeul, Brad; Vaca, Federico

    2012-01-01

    Objective To assess drinking patterns of Spanish-speaking patients using a bilingual Computerized Alcohol Screening and brief Intervention (CASI) tablet computer equipped with the Alcohol Use Disorders Identification Test (AUDIT). Methods This retrospective study was conducted in a tertiary university hospital emergency department (ED) between 2006 and 2010. Data from 1,816 Spanish-speaking ED patients was analyzed using descriptive statistics, the chi-square test for independence, and the Kruskal-Wallis rank sum test for comparisons using quantitative variables. Results Overall, 15% of Spanish-speaking patients were at-risk drinkers, and 5% had an AUDIT score consistent with alcohol dependency (≥20). A higher percentage of Spanish-speaking males than females were at-risk drinkers or likely dependent. Spanish speaking males exhibited higher frequency of drinking days per week and higher number of drinks per day compared to females. Among older patients, non-drinking behavior increased and at-risk drinkers decreased. The majority of males and females were ready to change their behavior after the CASI intervention; 61% and 69% respectively scored 8-10. Conclusions This study indicated that CASI was an effective tool for detecting at-risk and likely dependent drinking behavior in Spanish-speaking ED patients. The majority of patients were ready to change their drinking behavior. More alcohol screening and brief intervention tools should be tested and become readily accessible for Spanish-speaking patients. PMID:23577910

  20. The pedestrian behaviour of Spanish adolescents.

    PubMed

    Sullman, M J M; Gras, M E; Font-Mayolas, S; Masferrer, L; Cunill, M; Planes, M

    2011-06-01

    Adolescent pedestrians are a particularly vulnerable group of road users. This research tested the applicability of the recently developed Adolescent Road user Behaviour Questionnaire (ARBQ) amongst a sample of 2006 Spanish adolescents. Confirmatory Factor Analysis of the full scale found that the original three factors did not adequately fit the data, but an acceptable fit was obtained for the shortened 21-item version of the scale. In line with research from the UK, the present study found that males reported more unsafe road crossing behaviour and playing on the roads, but there was no gender difference for engaging in planned protective behaviour. This research also confirmed that unsafe road crossing behaviour increased with age, while dangerous playing on the road and planned protective behaviours both decreased with age. The present study also confirmed that the ARBQ is a useful tool for investigating the safety-related behaviour of adolescents on the road.

  1. Mineral profile of Spanish commercial baby food.

    PubMed

    Mir-Marqués, Alba; González-Masó, Anna; Cervera, M Luisa; de la Guardia, Miguel

    2015-04-01

    Commercial baby foods are an important part of the daily intake of babies from 6 to 12 months. The mineral profile of commercial baby foods in Spain was determined to establish levels of essential and non-essential elements, and their contribution to adequate intake (AI) and estimated average requirement (EAR). Thirty-five jars of commercial foods containing meat, fish, vegetables and fruit were obtained from the Spanish market and the mineral composition determined for 14 elements. In general, the baby foods analysed were sufficient for an adequate mineral intake, but contributions to AI and EAR for iron, zinc and calcium were very low (5-20%, 10-60% and 10-70%, respectively). This deficiency could be associated with growth problems or diseases in adulthood, and fortification of commercial products is recommended.

  2. Detection of adulterated commercial Spanish beeswax.

    PubMed

    Serra Bonvehi, J; Orantes Bermejo, F J

    2012-05-01

    The physical and chemical parameters (melting point and saponification number), and the fraction of hydrocarbons, monoesters, acids and alcohols have been determined in 90 samples of Spanish commercial beeswax from Apis mellifera L. The adulteration with paraffins of different melting point, cow tallow, stearic acid, and carnauba wax were determined by HTGC-FID/MS detection, and the research was focussed mainly on paraffins and microcrystallines waxes. In general, the added adulterant can be identified by the presence of non-naturally beeswax components, and by the differences of values of selected components between pure and adulterated beeswax. The detection limits were determined using pure and adulterated beeswax with different amounts of added waxes (5%, 10%, 20% and 30%). Percentages higher than 1-5% of each adulterant can be detected in the mixtures. Paraffin waxes were confirmed in 33 of the 90 samples analysed at concentrations between 5% and 30%.

  3. Health services accessibility among Spanish elderly.

    PubMed

    Fernández-Mayoralas, G; Rodríguez, V; Rojo, F

    2000-01-01

    The paper aims to identify the variables that best explain the use of health services by people aged 65 and over in Spain. The data comes from the 1993 Spanish National Health Survey (ENSE 93). The conceptual framework is the model proposed by Andersen, who suggests that utilisation is a function of predisposition to use the services, the ability to use them and of need. A bivariate and multivariate analysis (SPSS-X Discriminant Procedure) is conducted to define the predictors that best discriminate users and non-users. The use of each health service is explained by a different set of variables. The need variables play a more important role in predicting the use of non-discretionary services that are more closely related to healing processes (medical consultations, emergencies and hospitalisation). The predisposing and enabling variables are more relevant in explaining the use of dental services, indicating a certain degree of inequity of these discretionary services. PMID:10622691

  4. First evidence of spirolides in Spanish shellfish.

    PubMed

    Villar González, A; Rodríguez-Velasco, M L; Ben-Gigirey, B; Botana, L M

    2006-12-15

    During the months of November and December 2005, a harmful algal bloom in the northwestern region of Spain caused the accumulation of different algal toxins in several types of shellfish. Many of the shellfish were contaminated at levels above European regulatory limit, presenting serious risks for human health. The analysis of mussels sampled in the affected areas to search for lipophilic toxins, using liquid chromatography tandem mass spectrometry (LC-MS/MS), showed the presence of free okadaic acid (OA) and dinophysistoxin-2 (DTX-2) as well as esters of these toxins. The results also revealed the presence of minor amounts of 13-desmethyl spirolide C (SPX-1) in the analysed samples, although this toxin has never been reported before in Spain. The combination of different MS modes of operation, just as enhanced MS (EMS) and MS(3) experiments, allowed to confirm the first occurrence of spirolides in Spanish shellfish.

  5. Tracing the Spanish Language/Determinando el Origen del Idioma Espanol.

    ERIC Educational Resources Information Center

    Lozano, Anthony G.

    1980-01-01

    Discusses the history of the Spanish language in America and notes the influence of Caribbean languages, Nahuatl, and English on Spanish. Describes the archaisms in lexicon, phonology, and grammar of the Spanish of New Mexico and Colorado. Discusses Spanish language maintenance in Mexico, Puerto Rico, Cuba, and the United States. (SB)

  6. The Traits of Effective Spanish Writing = Las caracteristicas de la buena escritura en espanol. Second Edition.

    ERIC Educational Resources Information Center

    Flores, Will A.; Arrasmith, Dean G.

    This English-Spanish language report includes the rationale for creating an assessment model for Spanish writing, offering an overview of the components of high quality assessment for any subject area, particularly Spanish writing. It presents the characteristics of effective Spanish writing, rubrics for scoring student performance based on the…

  7. Salta a Cantar (Jump Up to Sing). Children's Songs in Spanish.

    ERIC Educational Resources Information Center

    Warner, Mona

    Since most children like to sing, singing Spanish songs is a learning experience that will be remembered. For Spanish speaking children, singing Spanish songs will build their self esteem and create a more comfortable environment. Children who do not speak Spanish will obtain a good feeling for the beauty of the language and will enjoy learning…

  8. Targeting Oral and Cultural Proficiency for Medical Personnel: An Examination of Current Medical Spanish Textbooks

    ERIC Educational Resources Information Center

    Hardin, Karol

    2012-01-01

    Demand for medical Spanish courses has grown with the rising needs of Spanish-speaking patients in the United States, but while there is no shortage of beginning medical Spanish textbooks, very few target the intermediate level. This article examines eighteen medical Spanish texts published in the last twenty years with respect to seven factors:…

  9. 38 CFR 3.712 - Improved pension elections; surviving spouses of Spanish-American War veterans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... elections; surviving spouses of Spanish-American War veterans. 3.712 Section 3.712 Pensions, Bonuses, and... spouses of Spanish-American War veterans. (a) General. A surviving spouse of a Spanish-American War... and attendance. A surviving spouse of a Spanish-American War veteran who is receiving or entitled...

  10. Orthogonal Higher Order Structure of the WISC-IV Spanish Using Hierarchical Exploratory Factor Analytic Procedures

    ERIC Educational Resources Information Center

    McGill, Ryan J.; Canivez, Gary L.

    2016-01-01

    As recommended by Carroll, the present study examined the factor structure of the Wechsler Intelligence Scale for Children-Fourth Edition Spanish (WISC-IV Spanish) normative sample using higher order exploratory factor analytic techniques not included in the WISC-IV Spanish Technical Manual. Results indicated that the WISC-IV Spanish subtests were…

  11. Asymmetrical Mixing Patterns of Spanish and English in a New Immigrant Community

    ERIC Educational Resources Information Center

    Smith, Daniel J.

    2009-01-01

    Analysis of Spanish and English speech in a new immigrant community of Latinos in Georgia, USA, shows that Spanish and English pattern differently. There is a higher frequency of Spanish sentences containing English words than English sentences containing Spanish words. But the reverse is true of grammatical influence without mixing words. There…

  12. La Lengua Espanol en los Estados Unidos (The Spanish Language in the United States).

    ERIC Educational Resources Information Center

    Barnach-Calbo, Ernesto

    This report on the use of the Spanish language in the United States discusses the Spanish-speaking population, the language itself, and bilingual education in the United States. The background about the Spanish-speaking population includes the following topics: (1) "A Nations of Immigrants," (2) "The Population of the Spanish-Speaking Minority,"…

  13. Cuentos Faciles. Habia una vez.... (Simple Stories. There was a Time....) (Presenting Simple Stories in Spanish.)

    ERIC Educational Resources Information Center

    Arroyo, Nancy; And Others

    For Spanish-speaking children, simple stories in Spanish, told in a natural language suitable for their age, are not only entertaining, but a means of developing vocabulary and concepts. Non-Spanish-speaking children, too, need exposure to more language than they can understand word for word. However, the simple stories for the Spanish speaker…

  14. How Important Is Teaching Phonemic Awareness to Children Learning to Read in Spanish?

    ERIC Educational Resources Information Center

    Goldenberg, Claude; Tolar, Tammy D.; Reese, Leslie; Francis, David J.; Bazán, Antonio Ray; Mejía-Arauz, Rebeca

    2014-01-01

    This comparative study examines relationships between phonemic awareness and Spanish reading skill acquisition among three groups of Spanish-speaking first and second graders: children in Mexico receiving reading instruction in Spanish and children in the United States receiving reading instruction in either Spanish or English. Children were…

  15. Vida Hispanica: The Spanish and Portuguese Journal of the Association for Language Learning, 1994-1997.

    ERIC Educational Resources Information Center

    Hollyman, John, Ed.; Turk, Phil, Ed.

    1997-01-01

    This journal focuses on the learning and teaching of Spanish and Portuguese. Selected articles include the following: "Word Associations in Spanish"; "A Woman of Substance? The Role of Andrea in Nada"; "Spanish for Business"; "Subtitles as a Teaching Technique"; "The Writing Workshop"; "Dialogue of the Deaf?""Corpus-based Analysis of Spanish";…

  16. 38 CFR 3.712 - Improved pension elections; surviving spouses of Spanish-American War veterans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... elections; surviving spouses of Spanish-American War veterans. 3.712 Section 3.712 Pensions, Bonuses, and... spouses of Spanish-American War veterans. (a) General. A surviving spouse of a Spanish-American War... and attendance. A surviving spouse of a Spanish-American War veteran who is receiving or entitled...

  17. 38 CFR 3.712 - Improved pension elections; surviving spouses of Spanish-American War veterans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... elections; surviving spouses of Spanish-American War veterans. 3.712 Section 3.712 Pensions, Bonuses, and... spouses of Spanish-American War veterans. (a) General. A surviving spouse of a Spanish-American War... and attendance. A surviving spouse of a Spanish-American War veteran who is receiving or entitled...

  18. 38 CFR 3.712 - Improved pension elections; surviving spouses of Spanish-American War veterans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... elections; surviving spouses of Spanish-American War veterans. 3.712 Section 3.712 Pensions, Bonuses, and... spouses of Spanish-American War veterans. (a) General. A surviving spouse of a Spanish-American War... and attendance. A surviving spouse of a Spanish-American War veteran who is receiving or entitled...

  19. 38 CFR 3.712 - Improved pension elections; surviving spouses of Spanish-American War veterans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... elections; surviving spouses of Spanish-American War veterans. 3.712 Section 3.712 Pensions, Bonuses, and... spouses of Spanish-American War veterans. (a) General. A surviving spouse of a Spanish-American War... and attendance. A surviving spouse of a Spanish-American War veteran who is receiving or entitled...

  20. A Non-Traditional Approach to the Teaching of Urban Spanish and Caribbean Literature.

    ERIC Educational Resources Information Center

    Angerosa, Nicholas F.

    Two courses in the La Salle University (Philadelphia, Pennsylvania) M.A. Program in Bilingual-Bicultural (Spanish) Studies are described: Urban Spanish and Caribbean Literature. The urban Spanish component consists of five courses, one of which is intensive, to provide broad exposure to the technical or practical Spanish encountered in the…

  1. Collections and Services for the Spanish-Speaking: Issues and Resources.

    ERIC Educational Resources Information Center

    Marquis, Solina Kasten

    2003-01-01

    Describes factors that have hindered Spanish-language collection development and suggests strategies and tools that can help the non-Spanish-speaking librarian select and acquire Spanish-language monographs, periodicals, and audiovisual media for adult and youth audiences. Provides lists of selected resources for Spanish-language and Latino book…

  2. Spelling impairments in Spanish dyslexic adults.

    PubMed

    Afonso, Olivia; Suárez-Coalla, Paz; Cuetos, Fernando

    2015-01-01

    Spelling deficits have repeatedly been observed in children with dyslexia. However, the few studies addressing this issue in dyslexic adults have reported contradictory results. We investigated whether Spanish dyslexics show spelling deficits in adulthood and which components of the writing production process might be impaired in developmental dyslexia. In order to evaluate the involvement of the lexical and the sublexical routes of spelling as well as the graphemic buffer, lexical frequency, phonology-to-orthography consistency and word length were manipulated in two writing tasks: a direct copy transcoding task and a spelling-to-dictation task. Results revealed that adults with dyslexia produced longer written latencies, inter-letter intervals, writing durations and more errors than their peers without dyslexia. Moreover, the dyslexics were more affected by lexical frequency and word length than the controls, but both groups showed a similar effect of P-O consistency. Written latencies also revealed that while the dyslexics initiated the response later in the direct copy transcoding task than in the spelling-to-dictation task, the controls showed the opposite pattern. However, the dyslexics were slower than the controls in both tasks. Results were consistent with the hypothesis that spelling difficulties are present in adults with dyslexia, at least in a language with a transparent orthography such as Spanish. These difficulties seem to be associated with a deficit affecting both lexical processing and the ability to maintain information about the serial order of the letters in a word. However, the dyslexic group did not differ from the control group in the application of the P-O conversion procedures. The spelling impairment would be in addition to the reading deficit, leading to poorer performance in direct copy transcoding compared to spelling-to-dictation.

  3. Spelling impairments in Spanish dyslexic adults

    PubMed Central

    Afonso, Olivia; Suárez-Coalla, Paz; Cuetos, Fernando

    2015-01-01

    Spelling deficits have repeatedly been observed in children with dyslexia. However, the few studies addressing this issue in dyslexic adults have reported contradictory results. We investigated whether Spanish dyslexics show spelling deficits in adulthood and which components of the writing production process might be impaired in developmental dyslexia. In order to evaluate the involvement of the lexical and the sublexical routes of spelling as well as the graphemic buffer, lexical frequency, phonology-to-orthography consistency and word length were manipulated in two writing tasks: a direct copy transcoding task and a spelling-to-dictation task. Results revealed that adults with dyslexia produced longer written latencies, inter-letter intervals, writing durations and more errors than their peers without dyslexia. Moreover, the dyslexics were more affected by lexical frequency and word length than the controls, but both groups showed a similar effect of P-O consistency. Written latencies also revealed that while the dyslexics initiated the response later in the direct copy transcoding task than in the spelling-to-dictation task, the controls showed the opposite pattern. However, the dyslexics were slower than the controls in both tasks. Results were consistent with the hypothesis that spelling difficulties are present in adults with dyslexia, at least in a language with a transparent orthography such as Spanish. These difficulties seem to be associated with a deficit affecting both lexical processing and the ability to maintain information about the serial order of the letters in a word. However, the dyslexic group did not differ from the control group in the application of the P-O conversion procedures. The spelling impairment would be in addition to the reading deficit, leading to poorer performance in direct copy transcoding compared to spelling-to-dictation. PMID:25941507

  4. A website for astronomical news in Spanish

    NASA Astrophysics Data System (ADS)

    Ortiz-Gil, A.

    2008-06-01

    Noticias del Cosmos is a collection of web pages within the Astronomical Observatory of the University of Valencia's website where we publish short daily summaries of astronomical press releases. Most, if not all of, the releases are originally written in English, and often Spanish readers may find them difficult to understand because not many people are familiar with the scientific language employed in these releases. Noticias del Cosmos has two principal aims. First, we want to communicate the latest astronomical news on a daily basis to a wide Spanish-speaking public who would otherwise not be able to read them because of the language barrier. Second, daily news can be used as a tool to introduce the astronomical topics of the school curriculum in a more immediate and relevant way. Most of the students at school have not yet reached a good enough level in their knowledge of English to fully understand a press release, and Noticias del Cosmos offers them and their teachers this news in their mother tongue. During the regular programme of school visits at the Observatory we use the news as a means of showing that there is still a lot to be discovered. So far the visits to the website have been growing steadily. Between June 2003 and June 2007 we had more than 30,000 visits (excluding 2006). More than 50% of the visits come from Spain, followed by visitors from South and Central America. The feedback we have received from teachers so far has been very positive, showing the usefulness of news items in the classroom when teaching astronomy.

  5. Orthographic learning in dyslexic Spanish children.

    PubMed

    Suárez-Coalla, Paz; Ramos, Sara; Alvarez-Cañizo, Marta; Cuetos, Fernando

    2014-07-01

    Reading fluency is one of the basic processes of learning to read. Children begin to develop fluency when they are able to form orthographic representations of words, which provide direct, smooth, and fast reading. Dyslexic children of transparent orthographic systems are mainly characterized by poor reading fluency (Cuetos & Suárez-Coalla 2009; Spinelli, De Luca, Di Filippo, Mancini, Martelli, & Zoccolotti, 2005; Wimmer, 1993). Therefore, the main problem for these children could be the difficulty in developing orthographic representations of the words they read. The aim of this study was to test the ability of dyslexic Spanish-speaking children (whose native language is Spanish) to develop orthographic representations and determine if the context helps them. For this, two experiments were conducted with a group of 100 children, 7-12 years of age. The groups were comprised of 20 dyslexics, 40 chronological age-matched controls and 40 reading level-matched controls. In the first experiment, eight unfamiliar words (four short and four long) were presented six times within the context of a story. In the second experiment, eight pseudowords were presented on a computer and the children had to read them aloud. In both experiments, the reading and articulation times of experimental and control stimuli were compared, before and after the training. Children without dyslexia showed a decrease of the influence of length of word on reading speed, indicating a lexical reading, while for dyslexic children, the influence of length remained unchanged. These results appeared when the stimuli were presented in the context of a story as well as when presented in isolation. In short, our results describe that dyslexic children of transparent orthographic systems have problems in developing orthographic representations of words. PMID:25056668

  6. AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease

    PubMed Central

    Haskin, Joseph; Szargel, Raymonde; Shani, Vered; Mekies, Lucy N.; Rott, Ruth; Lim, Grace G. Y.; Lim, Kah-Leong; Bandopadhyay, Rina; Wolosker, Herman; Engelender, Simone

    2013-01-01

    Parkin E3 ubiquitin-ligase activity and its role in mitochondria homeostasis are thought to play a role in Parkinson's disease (PD). We now report that AF-6 is a novel parkin interacting protein that modulates parkin ubiquitin-ligase activity and mitochondrial roles. Parkin interacts with the AF-6 PDZ region through its C-terminus. This leads to ubiquitination of cytosolic AF-6 and its degradation by the proteasome. On the other hand, endogenous AF-6 robustly increases parkin translocation and ubiquitin-ligase activity at the mitochondria. Mitochondrial AF-6 is not a parkin substrate, but rather co-localizes with parkin and enhances mitochondria degradation through PINK1/parkin-mediated mitophagy. On the other hand, several parkin and PINK1 juvenile disease-mutants are insensitive to AF-6 effects. AF-6 is present in Lewy bodies and its soluble levels are strikingly decreased in the caudate/putamen and substantia nigra of sporadic PD patients, suggesting that decreased AF-6 levels may contribute to the accumulation of dysfunctional mitochondria in the disease. The identification of AF-6 as a positive modulator of parkin translocation to the mitochondria sheds light on the mechanisms involved in PD and underscores AF-6 as a novel target for future therapeutics. PMID:23393160

  7. Spanish stop-rhotic sequences in Spanish-Basque bilinguals and second language learners: An acoustic study

    NASA Astrophysics Data System (ADS)

    Weissglass, Christine A.

    This dissertation investigates transfer and markedness in bilingual and L2 Spanish stop-rhotic sequences (e.g., the 'br' in brisa 'breeze'). It also examines the phonetics-phonology interface in Spanish. To this end, it explores the production of these sequences in two different experiments. Experiment 1 compares the production of these sequences by 6 Spanish monolinguals and 6 Spanish-Basque bilinguals. Experiment 2 does so for 25 L2 learners and 5 native Spanish speakers. Acoustic analysis of these sequences revealed that Spanish-Basque bilinguals produced trills 5% of the time whereas Spanish monolinguals did not have any trills. Additionally, fricative rhotics and coarticulation accounted for 35% of L2 realizations, but were not present in the native Spanish speaker dataset. These findings indicate a role for transfer in both bilingual and L2 phonological acquisition, although it is more prevalent in the L2 learner dataset. This is in line with the Speech Learning Model (Flege, 1995), which posits a stronger role for transfer amongst late learners (i.e., L2 learners) than early learners (i.e., Spanish-Basque bilinguals). In order to examine the role of markedness in bilingual and L2 phonological acquisition, this dissertation investigates the role of sonority in bilingual and L2 Spanish syllable structure. To do so, it proposes a sonority hierarchy for rhotic variants based on their specifications for voicing, intensity and continuancy. According to this hierarchy, approximant rhotics are the most sonorous, followed by taps, trills and fricative rhotics. Therefore, approximant rhotics were expected to be the most common realization followed by taps, trills and fricative rhotics. Although Spanish monolinguals adhered to this expectation, the other groups did not; taps were the most common realization for Spanish-Basque bilinguals, L2 learners, and native Spanish speakers and fricative rhotics were more common than trills for Spanish-Basque bilinguals and L2

  8. Statin Therapy for the Prevention of Atrial Fibrillation Trial (SToP AF trial)

    PubMed Central

    Negi, Smita; Shukrullah, Irfan; Veledar, Emir; Bloom, Heather L.; Jones, Dean P.; Dudley, Samuel C.

    2010-01-01

    Background Inflammation and oxidative stress are associated with atrial fibrillation (AF). Statins have antioxidant and anti-inflammatory properties. We tested if atorvastatin reduced AF recurrence after DC cardioversion (CV) by modifying systemic oxidative stress and inflammation. (NCT00252967) Methods and Results In a randomized, double-blinded, placebo-controlled trial, patients with atrial fibrillation/flutter (AF) were randomized to receive either atorvastatin 80 mg (n=33) or placebo (n=31) before CV. Treatment was continued for 12 months or until AF recurred. Serum oxidative stress markers (ratios of oxidized to reduced glutathione and cysteine, derivatives of reactive oxygen species, isoprostanes) and inflammatory markers [ high sensitivity C- reactive protein (hs-CRP), interleukin-6 (IL-6), interleukin-1β(IL-1β), tumor necrosis factor-α (TNFα)] were measured at baseline and on follow-up. AF recurred in 22 (66.7%) of atorvastatin and 26 (83.9%) of placebo group (p=0.2). The adjusted hazard ratio of having recurrence on atorvastatin versus on placebo was 0.99 (95% CI: 0.98-1.01, p=0.3). There was no significant difference in the time to recurrence using Kaplan-Meier survival estimates (median (IR): 29 (2-145) days vs. 22 (7-70) days, p=0.9). While no significant effect was seen on oxidative stress, 2 of 4 inflammatory markers, IL-6 (adjusted OR: 0.59, 95% CI: 0.35-0.97, p= 0.04) and hs-CRP (adjusted OR: 0.59, 95% CI: 0.37-0.95, p=0.03) were significantly lowered with atorvastatin. Cholesterol levels significantly decreased with atorvastatin (p=0.03). Conclusions High dose atorvastatin did not reduce the recurrence of AF after CV. It reduced selective markers of inflammation without affecting systemic oxidative stress. Failure of atorvastatin to prevent AF recurrence may be due to its failure to affect oxidative stress. PMID:20946227

  9. Detail view of Spanish tower on south facade of #157 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of Spanish tower on south facade of #157 - National Home for Disabled Volunteer Soldiers, Pacific Branch, Mental Health Buildings, 11301 Wilshire Boulevard, West Los Angeles, Los Angeles County, CA

  10. Community Colleges and Spanish Language Instruction: Peer Pedagogy in Prison

    ERIC Educational Resources Information Center

    Drew, Jenifer D.; Duval, José; Cyr, James R.

    2015-01-01

    Three authors describe a collaboration between a Massachusetts college and a nearby prison, which leveraged the volunteer efforts of a college professor by including incarcerated men who assisted in Spanish language teaching inside and outside the classroom.

  11. Syntactic Constraints on the Expression of Possession in Spanish.

    ERIC Educational Resources Information Center

    Kempchinsky, Paula

    1992-01-01

    In a discussion of possessives in Spanish, it is shown that three morphosyntactic constructs are systematically linked. The possessive dative construction, inalienable possession and nonrestrictive adjectives, and inalienable possession with subjects are examined. (25 references) (LB)

  12. Challenging Spanish: ways for nurses to become bilingual.

    PubMed

    Oderkirk, W

    1999-01-01

    A desire to provide culturally competent care to an increasing population of non-English-speakers may lead some nurses to consider learning another language as a way to minimize cross-cultural communication barriers. Nurses wishing to learn a second language may be surprised at the variety of ways to acquire bilingual skills, particularly in Spanish, the most common foreign language encountered in the United States. Reasons to learn Spanish are discussed and ways to do so are reviewed. Learning Spanish or another language can enrich the nurse-patient relationship, enhance nurses' self-esteem, and advance nurses' employment opportunities. Bilingual proficiency in English and Spanish (or another language) should be regarded as an authentic clinical skill supporting nurses' cultural and clinical competencies.

  13. Libros y mas libros: Recommended Children's Books in Spanish.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2000-01-01

    Provides an annotated bibliography of recommended Spanish-language children's books. A total of 15 books are grouped in the following categories: (1) books for the very young; (2) fiction; (3) folklore; (4) literature; (5) poetry; and (6) history. (EV)

  14. American Holidays for Spanish Students in the United States.

    ERIC Educational Resources Information Center

    Lancaster County School Board, PA.

    Three handouts give the history of three holidays celebrated in the United States: Christmas, Halloween, and St. Valentine's Day. Each holiday is described in Spanish and in English for use in bilingual classrooms. (CFM)

  15. Noteworthy Books in Spanish for Children and Adolescents.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1998-01-01

    Lists Spanish language books for children ranging from wordless picture books to adolescent love stories and translated popular novels. This year's list includes publishers from Latin America, in particular Mexico's Fondo de Cultura Economica. (MMU)

  16. A revised list of Spanish translations of operant terminology

    PubMed Central

    Gallegos, Xochitl; Colotla, Victor A.

    1980-01-01

    The experimental analysis of behavior has grown enormously in Latin America within the last decade. This paper offers an updating revision of suggested Spanish translations of operant expressions. PMID:16812173

  17. English Loanwords in Chicano Spanish: Characterization and Rationale.

    ERIC Educational Resources Information Center

    Smead, Robert N.

    1998-01-01

    Discusses one highly visible and often stigmatized feature of Chicano Spanish--lexical innovation due to intimate contact with English and mainstream culture. Discusses socio- and psycholinguistic factors that play a role in loanword formation. (Author/VWL)

  18. The Open Cluster Chemical Abundances from Spanish Observatories Survey (OCCASO)

    NASA Astrophysics Data System (ADS)

    Carrera, R.; Casamiquela, L.; Balaguer-Núñez, L.; Jordi, C.; Pancino, E.; Allende-Prieto, C.; Blanco-Cuaresma, S.; Martínez-Vázquez, C. E.; Murabito, S.; del Pino, A.; Aparicio, A.; Gallart, C.; Recio-Blanco, A.

    2016-10-01

    We present the motivation, design and current status of the Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO). Using the high resolution spectroscopic facilities available at Spanish observatories, OCCASO will derive chemical abundances in a sample of 20 to 25 OCs older than 0.5 Gyr. This sample will be used to study in detail the formation and evolution of the Galactic disk using OCs as tracers.

  19. Validity of the Spanish version of the Emotional Labour Scale.

    PubMed

    Picardo, Juan M; López-Fernández, Consuelo; Hervás, María José Abellán

    2014-06-01

    In this article we address concerns raised by Brumit and Glenn (2013) regarding the validity of the Spanish version of the Emotional Labour Scale (ELS). We respond to requests in relation to the translated version of the scale and the eigenvalue series. We also give an explanation of the differences in results between the original version and the Spanish version of the scale. PMID:24581889

  20. The Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO)

    NASA Astrophysics Data System (ADS)

    Carrera, R.; Casamiquela, L.; Balaguer-Núñez, L.; Jordi, C.; Pancino, E.; Allende-Prieto, C.; Blanco-Cuaresma, S.; Martínez-Vázquez, C. E.; Murabito, S.; del Pino, A.; Aparicio, A.; Gallart, C.; Recio-Blanco, A.

    2015-05-01

    We present the motivation, design and current status of the Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO). Using the high resolution spectroscopic facilities available at Spanish observatories, OCCASO will derive chemical abundances in a sample of 20 to 25 OCs older than 0.5 Gyr. This sample will be used to study in detail de formation and evolution of the Galactic disc using OCs as tracers.

  1. [Strategic orientation of the Spanish Society of Internal Medicine].

    PubMed

    García Alegría, J; Conthe Gutiérrez, P

    2011-01-01

    The council of the Spanish Society of Internal express its position within the general society, origins, objectives, and strategies. The Spanish Foundation of Internal Medicina promotes scientific research and continued education within Internal Medicine, by means of the 17 working groups. Taking into account the actual situation, the authors analyze this situation and formulate the strategy objectives for the upcoming years. These contents are summarized in 10 message decalogue that express the essence and future of Internal Medicine.

  2. Low strain, long life creep fatigue of AF2-1DA and INCO 718

    NASA Technical Reports Server (NTRS)

    Thakker, A. B.; Cowles, B. A.

    1983-01-01

    Two aircraft turbine disk alloys, GATORIZED AF2-DA and INCO 718 were evaluated for their low strain long life creep-fatigue behavior. Static (tensile and creep rupture) and cyclic properties of both alloys were characterized. The cntrolled strain LCF tests were conducted at 760 C (1400 F) and 649 C (1200 F) for AF2-1DA and INCO 718, respectively. Hold times were varied for tensile, compressive and tensile/compressive strain dwell (relaxation) tests. Stress (creep) hold behavior of AF2-1DA was also evaluated. Generally, INCO 718 exhibited more pronounced reduction in cyclic life due to hold than AF2-1DA. The percent reduction in life for both alloys for strain dwell tests was greater at low strain ranges (longer life regime). Changing hold time from 0 to 0.5, 2.0 and 15.0 min. resulted in corresponding reductions in life. The continuous cycle and cyclic/dwell initiation failure mechanism was predominantly transgranular for AF2-1DA and intergranular for INCO 718.

  3. The binding of (3H)AF-DX 384 to rat ileal smooth muscle muscarinic receptors

    SciTech Connect

    Entzeroth, M.; Mayer, N. )

    1991-01-01

    The tritiated cardioselective muscarinic antagonist AF-DX 384 (5,11-dihydro-11-(2-(-(8-dipropylamino)methyl)-1-piperidinyl-ethyl-amino-carbonyl)-6H-pyrido (2,3-b) (1,4)benzodiazepin-6-one) was used to label muscarinic receptors in the rat ileum. Saturation binding to membrane suspensions revealed a high affinity binding site with a Kd of 9.2 nM. The maximal number of binding sites labeled in this tissue (Bmax) is 237 fmol/mg protein. The association and dissociation kinetics were well represented by single exponential reactions, and the dissociation constant obtained from the ratio of rate constants was in agreement with that derived from saturation experiments. Specific binding was inhibited by muscarinic antagonists with a rank order of potencies of atropine (pKi: 8.80) greater than 4-DAMP (pKi: 8.23) = AF-DX 384 (pKi: 8.20) greater than AF-DX 116 (pKi: 7.09) = hexahydro-sila-difenidol (pKi: 6.97) greater than pirenzepine (pKi: 6.49) and is consistent with the interaction of (3H)AF-DX 384 with muscarinic receptors of the M2 subtype. It can be concluded that (3H)AF-DX 384 can be used to selectively label M2 muscarinic receptors in heterogeneous receptor populations.

  4. A simple web-based tool to compare freshwater fish data collected using AFS standard methods

    USGS Publications Warehouse

    Bonar, Scott A.; Mercado-Silva, Norman; Rahr, Matt; Torrey, Yuta T.; Cate, Averill

    2016-01-01

    The American Fisheries Society (AFS) recently published Standard Methods for Sampling North American Freshwater Fishes. Enlisting the expertise of 284 scientists from 107 organizations throughout Canada, Mexico, and the United States, this text was developed to facilitate comparisons of fish data across regions or time. Here we describe a user-friendly web tool that automates among-sample comparisons in individual fish condition, population length-frequency distributions, and catch per unit effort (CPUE) data collected using AFS standard methods. Currently, the web tool (1) provides instantaneous summaries of almost 4,000 data sets of condition, length frequency, and CPUE of common freshwater fishes collected using standard gears in 43 states and provinces; (2) is easily appended with new standardized field data to update subsequent queries and summaries; (3) compares fish data from a particular water body with continent, ecoregion, and state data summaries; and (4) provides additional information about AFS standard fish sampling including benefits, ongoing validation studies, and opportunities to comment on specific methods. The web tool—programmed in a PHP-based Drupal framework—was supported by several AFS Sections, agencies, and universities and is freely available from the AFS website and fisheriesstandardsampling.org. With widespread use, the online tool could become an important resource for fisheries biologists.

  5. [AF + BAF for treating effluent in the sewage plant of the resin and chemical industry park].

    PubMed

    Tu, Yong; Liu, Wei-Jing; Zhang, Yao-Hui; Xu, Jun; Tang, Min; Chen, Yong; Bai, Yong-Gang

    2014-06-01

    The anaerobic filter (AF) and biological aerated filter (BAF) were employed to treat the effluent in a sewage plant of the resin and chemical industry park. The ceramsite was used in BAF. In this study, the influent COD was 200-300 mg x L(-1) and the pilot model scale was 2-4 L x d(-1). According to the results, the AF-BAF treatment had a good effect on organic wastewater. When the AF HRT was 24 h and BAF was 12 h, the removal of COD reached 73.4%, and that of NH4(+)-N reached 93.8%. From gas chromatography-mass spectrometry (GC-MS) and three-dimensional fluorescence analysis, it was found that small organic molecules and microbial metabolites could be removed effectively. However, there was no obviously effect on the removal of saturated alkane and nitrogenous heterocyclic compounds. From the denature gradient gel electrophoresis (DGGE) spectra analysis, it was shown that there were more kinds of microorganism in the sludge of the AF than in the up-flow anaerobic sludge bed (UASB), which indicates that the AF-BAF system is more effective on treating effluent in a sewage plant of the resin and chemical industry park.

  6. GLA-AF, an emulsion-free vaccine adjuvant for pandemic influenza.

    PubMed

    Clegg, Christopher H; Roque, Richard; Perrone, Lucy A; Rininger, Joseph A; Bowen, Richard; Reed, Steven G

    2014-01-01

    The ongoing threat from Influenza necessitates the development of new vaccine and adjuvant technologies that can maximize vaccine immunogenicity, shorten production cycles, and increase global vaccine supply. Currently, the most successful adjuvants for Influenza vaccines are squalene-based oil-in-water emulsions. These adjuvants enhance seroprotective antibody titers to homologous and heterologous strains of virus, and augment a significant dose sparing activity that could improve vaccine manufacturing capacity. As an alternative to an emulsion, we tested a simple lipid-based aqueous formulation containing a synthetic TLR4 ligand (GLA-AF) for its ability to enhance protection against H5N1 infection. GLA-AF was very effective in adjuvanting recombinant H5 hemagglutinin antigen (rH5) in mice and was as potent as the stable emulsion, SE. Both adjuvants induced similar antibody titers using a sub-microgram dose of rH5, and both conferred complete protection against a highly pathogenic H5N1 challenge. However, GLA-AF was the superior adjuvant in ferrets. GLA-AF stimulated a broader antibody response than SE after both the prime and boost immunization with rH5, and ferrets were better protected against homologous and heterologous strains of H5N1 virus. Thus, GLA-AF is a potent emulsion-free adjuvant that warrants consideration for pandemic influenza vaccine development. PMID:24551202

  7. Neuronal and microvascular alterations induced by the cholinergic toxin AF64A in the rat retina.

    PubMed

    Gómez-Ramos, P; Galea, E; Estrada, C

    1990-06-18

    The choline analogue ethylcholine mustard aziridinium ion (AF64A) produces both neuronal and non-neuronal alterations in the rat retina. The possible involvement of the retinal capillaries in the origin of the apparently non-specific lesions has been investigated. Two hours after a single intraocular injection of 5 nmol AF64A, ultrastructural alterations were observed in neurons of the inner nuclear layer and the ganglion cell layer, where cholinergic cells are located. One week later, the number of cholinergic neurons, identified by choline acetyltransferase immunohistochemistry, was decreased to 65% of control, the neurons located in the inner nuclear layer being more sensitive than those in the ganglion cell layer. The same dose of AF64A also induced ultrastructural changes in retinal capillaries, which showed a significant increase in the number of pinocytotic vesicles and microvilli in the endothelial cells, 2-5 h after the toxin administration. One day later, arterioles and capillaries presented contracted profiles and the lumen was occasionally lost. The sensitivity of endothelial cells to the toxic effects of AF64A may be explained by the presence in the cerebral endothelium of a choline transport mechanism with an affinity close to that of cerebral synaptosomes. In vitro, both neuronal and endothelial choline uptake systems were equally sensitive to the toxin inhibitory effect. The early and severe vascular alterations induced in the retinal microvessels by AF64A may produce changes in blood perfusion and capillary permeability that could account for the apparently non-specific histological damage.

  8. Detection of human tumor cells by amplicon fusion site polymerase chain reaction (AFS-PCR)

    PubMed Central

    Weber, Axel; Taube, Sylvia; Starke, Sven; Bergmann, Eckhard; Christiansen, Nina Merete; Christiansen, Holger

    2011-01-01

    Reliable diagnostic strategies for individuals with cancer demand practical methods for highly sensitive and specific detection of tumor cells. Amplification of genomic regions that include putative oncogenes is common in tumor cells of various types. Genomic array platforms offer the opportunity to identify and precisely map amplified genomic regions (ampGRs). The stable existence of these tumor cell–specific genomic aberrations during and after therapy, in theory, make ampGRs optimal targets for cancer diagnostics. In this study, we mapped ampGRs around the proto-oncogene MYCN of human neuroblastomas using a high-resolution tiling array (HR-TA). Based on the HR-TA data, we were able to precisely describe the telomeric and centromeric borders of the ampGRs and deduce virtual fusion sites of the joined ampGRs (amplicon fusion sites [AFSs]). These AFSs served as blueprints for the subsequent design of AFS bridging PCR assays (AFS-PCRs). Strikingly, these assays were absolutely tumor cell specific and capable of detecting 1 tumor cell in 1 × 106 to 8 × 106 control cells. We successfully proved the in vivo practicability of AFS-PCR by detecting and quantifying the specific AFS DNA of human MYCN-amplified neuroblastomas in the patients’ corresponding peripheral blood and bone marrow samples. Thus, we believe AFS-PCR could become a powerful and nevertheless feasible personalized diagnostic tool applicable to a large number of cancer patients, including children with MYCN-amplified neuroblastomas. PMID:21293059

  9. Detection of human tumor cells by amplicon fusion site polymerase chain reaction (AFS-PCR).

    PubMed

    Weber, Axel; Taube, Sylvia; Starke, Sven; Bergmann, Eckhard; Christiansen, Nina Merete; Christiansen, Holger

    2011-02-01

    Reliable diagnostic strategies for individuals with cancer demand practical methods for highly sensitive and specific detection of tumor cells. Amplification of genomic regions that include putative oncogenes is common in tumor cells of various types. Genomic array platforms offer the opportunity to identify and precisely map amplified genomic regions (ampGRs). The stable existence of these tumor cell–specific genomic aberrations during and after therapy, in theory, make ampGRs optimal targets for cancer diagnostics. In this study, we mapped ampGRs around the proto-oncogene MYCN of human neuroblastomas using a high-resolution tiling array (HR-TA). Based on the HR-TA data, we were able to precisely describe the telomeric and centromeric borders of the ampGRs and deduce virtual fusion sites of the joined ampGRs (amplicon fusion sites [AFSs]). These AFSs served as blueprints for the subsequent design of AFS bridging PCR assays (AFS-PCRs). Strikingly, these assays were absolutely tumor cell specific and capable of detecting 1 tumor cell in 1 × 10(6) to 8 × 10(6) control cells. We successfully proved the in vivo practicability of AFS-PCR by detecting and quantifying the specific AFS DNA of human MYCN-amplified neuroblastomas in the patients’ corresponding peripheral blood and bone marrow samples. Thus, we believe AFS-PCR could become a powerful and nevertheless feasible personalized diagnostic tool applicable to a large number of cancer patients, including children with MYCN-amplified neuroblastomas.

  10. Low strain, long life creep fatigue of AF2-1DA and INCO 718

    SciTech Connect

    Thakker, A.B.; Cowles, B.A.

    1983-04-01

    Two aircraft turbine disk alloys, GATORIZED AF2-DA and INCO 718 were evaluated for their low strain long life creep-fatigue behavior. Static (tensile and creep rupture) and cyclic properties of both alloys were characterized. The cntrolled strain LCF tests were conducted at 760 C (1400 F) and 649 C (1200 F) for AF2-1DA and INCO 718, respectively. Hold times were varied for tensile, compressive and tensile/compressive strain dwell (relaxation) tests. Stress (creep) hold behavior of AF2-1DA was also evaluated. Generally, INCO 718 exhibited more pronounced reduction in cyclic life due to hold than AF2-1DA. The percent reduction in life for both alloys for strain dwell tests was greater at low strain ranges (longer life regime). Changing hold time from 0 to 0.5, 2.0 and 15.0 min. resulted in corresponding reductions in life. The continuous cycle and cyclic/dwell initiation failure mechanism was predominantly transgranular for AF2-1DA and intergranular for INCO 718.

  11. Prevention of Adolescent Depression in the Spanish-Speaking World

    PubMed Central

    Horn, Andrea B.; Cañizares, Catalina; Gómez, Yvonne

    2014-01-01

    This paper aims at presenting programs targeted at the prevention of adolescent depression applied with Spanish-speaking populations that have been developed in Spanish-speaking countries and are mostly published in Spanish. These programs have been developed under different cultural contexts in Spain and Latin-America. The main goal of this paper is to make the studies and movements of the Spanish-speaking literature in this field accessible to the non-Spanish-speaking part of the research community. Therefore, after an introduction referring to possible cultural differences regarding depression in general and epidemiological basics, several programs are introduced. In total 11 programs will be shortly presented and discussed. After revising the programs it can be concluded that in the Spanish-speaking world many programs have been developed and conducted following current state of the art-approaches for adolescent depression prevention. Further research is needed especially targeting possible cultural and contextual aspects of prevention measures and their efficacy and efficiency. PMID:24871258

  12. Prevention of adolescent depression in the Spanish-speaking world.

    PubMed

    Horn, Andrea B; Cañizares, Catalina; Gómez, Yvonne

    2014-06-01

    This paper aims at presenting programs targeted at the prevention of adolescent depression applied with Spanish-speaking populations that have been developed in Spanish-speaking countries and are mostly published in Spanish. These programs have been developed under different cultural contexts in Spain and Latin-America. The main goal of this paper is to make the studies and movements of the Spanish-speaking literature in this field accessible to the non-Spanish-speaking part of the research community. Therefore, after an introduction referring to possible cultural differences regarding depression in general and epidemiological basics, several programs are introduced. In total 11 programs will be shortly presented and discussed. After revising the programs it can be concluded that in the Spanish-speaking world many programs have been developed and conducted following current state of the art-approaches for adolescent depression prevention. Further research is needed especially targeting possible cultural and contextual aspects of prevention measures and their efficacy and efficiency.

  13. Teaching Culture and Improving Language Skills through a Cinematic Lens: A Course on Spanish Film in the Undergraduate Spanish Curriculum.

    ERIC Educational Resources Information Center

    Stephens, Julie L.

    2001-01-01

    Explores the role of a course on Spanish cinema in an undergraduate, university-level curriculum in terms of its potential to acquaint students with significant cultural issues and to develop language skills. (Author/VWL)

  14. An Evaluation of the Impacts of AF-M315E Propulsion Systems for Varied Mission Applications

    NASA Technical Reports Server (NTRS)

    Deans, Matthew C.; Oleson, Steven R.; Fittje, James; Colozza, Anthony; Packard, Tom; Gyekenyesi, John; McLean, Christopher H.; Spores, Ronald A.

    2015-01-01

    The purpose of the AF-M315E COMPASS study is to identify near-term (3-5 years) and long term (5 years +) opportunities for infusion, specifically the thruster and associated component technologies being developed as part of the GPIM project. Develop design reference missions which show the advantages of the AF-M315E green propulsion system. Utilize a combination of past COMPASS designs and selected new designs to demonstrate AF-M315E advantages. Use the COMPASS process to show the puts and takes of using AF-M315E at the integrated system level.

  15. AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

    PubMed Central

    Park, Jino; Schlederer, Michaela; Schreiber, Martin; Ice, Ryan; Merkel, Olaf; Bilban, Martin; Hofbauer, Sebastian; Kim, Soojin; Addison, Joseph; Zou, Jie; Ji, Chunyan; Bunting, Silvia T.; Wang, Zhengqi; Shoham, Menachem; Huang, Gang; Bago-Horvath, Zsuzsanna; Gibson, Laura F.; Rojanasakul, Yon; Remick, Scot; Ivanov, Alexey; Pugacheva, Elena; Bunting, Kevin D.; Moriggl, Richard

    2015-01-01

    AF1q is an MLL fusion partner that was identified from acute myeloid leukemia (AML) patients with t (1; 11) (q21; q23) chromosomal abnormality. The function of AF1q is not yet fully known, however, elevated AF1q expression is associated with poor clinical outcomes in various malignancies. Here, we show that AF1q specifically binds to T-cell-factor-7 (TCF7) in the Wnt signaling pathway and results in transcriptional activation of CD44 as well as multiple downstream targets of the TCF7/LEF1. In addition, enhanced AF1q expression promotes breast cancer cell proliferation, migration, mammosphere formation, and chemo-resistance. In xenograft models, enforced AF1q expression in breast cancer cells also promotes liver metastasis and lung colonization. In a cohort of 63 breast cancer patients, higher percentages of AF1q-positive cancer cells in primary sites were associated with significantly poorer overall survival (OS), disease-free survival (DFS), and brain metastasis-free survival (b-MFS). Using paired primary/metastatic samples from the same patients, we demonstrate that AF1q-positive breast cancer cells become dynamically dominant in the metastatic sites compared to the primary sites. Our findings indicate that breast cancer cells with a hyperactive AF1q/TCF7/CD44 regulatory axis in the primary sites may represent “metastatic founder cells” which have invasive properties. PMID:26079538

  16. Pseudomonas syringae type III effector HopAF1 suppresses plant immunity by targeting methionine recycling to block ethylene induction

    PubMed Central

    Washington, Erica J.; Mukhtar, M. Shahid; Finkel, Omri M.; Wan, Li; Kieber, Joseph J.; Dangl, Jeffery L.

    2016-01-01

    HopAF1 is a type III effector protein of unknown function encoded in the genomes of several strains of Pseudomonas syringae and other plant pathogens. Structural modeling predicted that HopAF1 is closely related to deamidase proteins. Deamidation is the irreversible substitution of an amide group with a carboxylate group. Several bacterial virulence factors are deamidases that manipulate the activity of specific host protein substrates. We identified Arabidopsis methylthioadenosine nucleosidase proteins MTN1 and MTN2 as putative targets of HopAF1 deamidation. MTNs are enzymes in the Yang cycle, which is essential for the high levels of ethylene biosynthesis in Arabidopsis. We hypothesized that HopAF1 inhibits the host defense response by manipulating MTN activity and consequently ethylene levels. We determined that bacterially delivered HopAF1 inhibits ethylene biosynthesis induced by pathogen-associated molecular patterns and that Arabidopsis mtn1 mtn2 mutant plants phenocopy the effect of HopAF1. Furthermore, we identified two conserved asparagines in MTN1 and MTN2 from Arabidopsis that confer loss of function phenotypes when deamidated via site-specific mutation. These residues are potential targets of HopAF1 deamidation. HopAF1-mediated manipulation of Yang cycle MTN proteins is likely an evolutionarily conserved mechanism whereby HopAF1 orthologs from multiple plant pathogens contribute to disease in a large variety of plant hosts. PMID:27274076

  17. Effects of a Supplemental Spanish Oral Language Program on Sentence Length, Complexity, and Grammaticality in Spanish-Speaking Children Attending English-Only Preschools

    ERIC Educational Resources Information Center

    Restrepo, M. Adelaida; Castilla, Anny P.; Schwanenflugel, Paula J.; Neuharth-Pritchett, Stacey; Hamilton, Claire E.; Arboleda, Alejandra

    2010-01-01

    Purpose: The purpose of this study was to examine the effects of a supplemental Spanish language instruction program for children who spoke Spanish as their native language and were attending English-only preschool programs. Specifically, the study evaluated the program's effects on the children's Spanish sentence length in words, subordination…

  18. Enticing Spanish-Speaking Adolescents: Recent Books in Spanish for Every Taste/Cautivar a los Adolescentes Hispanohablantes: Libros Recientes en Espanol Para Todos los Gustos.

    ERIC Educational Resources Information Center

    Schon, Isabel

    1999-01-01

    Argues that books in Spanish can engage Spanish-speaking students in the reading process, and that fostering the love of reading is a necessary first step to reading proficiency in any language. Offers brief descriptions of 16 recently published books in Spanish, and describes a large database of recommended books for children and adolescents in…

  19. Oncogenic human papillomavirus (HPV) type distribution and HPV type 16 E6 variants in two Spanish population groups with different levels of HPV infection risk.

    PubMed

    Ortiz, M; Torres, M; Muñoz, L; Fernández-García, E; Canals, J; Cabornero, A I; Aguilar, E; Ballesteros, J; Del Amo, J; García-Sáiz, A

    2006-04-01

    The aim of this study is to determine oncogenic human papillomavirus (HPV) types and HPV type 16 (HPV16) variant distribution in two Spanish population groups, commercial sex workers and imprisoned women (CSW/IPW) and the general population. A multicenter cross-sectional study of 1,889 women from five clinical settings in two Spanish cities was conducted from May to November 2004. Oncogenic HPV infection was tested by an Hybrid Capture II (HC2) test, and positive samples were genotyped by direct sequencing using three different primer sets in L1 (MY09/11 and GP5+/GP6+) and E6/E7. HPV16 variants were identified by sequencing the E6, E2, and L1 regions. Four hundred twenty-five samples were positive for the HC2 test, 31.5% from CSW/IPW and 10.7% from the general population. HPV16 was the most frequent type. Distinct profiles of oncogenic HPV type prevalence were observed across the two populations. In order of decreasing frequency, HPV types 16, 31, 58, 66, 56, and 18 were most frequent in CSW/IPW women, and types 16, 31, 52, 68, 51, and 53 were most frequent in the general population. We analyzed HPV16 intratype variants, and a large majority (78.7%) belonged to the European lineage. AA variants were detected in 16.0% of cases. African variants belonging to classes Af1 (4.0%) and Af2 (1.3%) were detected. Different HPV types and HPV16 intratype variants are involved in oncogenic HPV infections in our population. These results suggest that HPV type distribution differs in CSW/IPW women and in the general population, although further analysis is necessary.

  20. Oncogenic Human Papillomavirus (HPV) Type Distribution and HPV Type 16 E6 Variants in Two Spanish Population Groups with Different Levels of HPV Infection Risk

    PubMed Central

    Ortiz, M.; Torres, M.; Muñoz, L.; Fernández-García, E.; Canals, J.; Cabornero, A. I.; Aguilar, E.; Ballesteros, J.; del Amo, J.; García-Sáiz, A.

    2006-01-01

    The aim of this study is to determine oncogenic human papillomavirus (HPV) types and HPV type 16 (HPV16) variant distribution in two Spanish population groups, commercial sex workers and imprisoned women (CSW/IPW) and the general population. A multicenter cross-sectional study of 1,889 women from five clinical settings in two Spanish cities was conducted from May to November 2004. Oncogenic HPV infection was tested by an Hybrid Capture II (HC2) test, and positive samples were genotyped by direct sequencing using three different primer sets in L1 (MY09/11 and GP5+/GP6+) and E6/E7. HPV16 variants were identified by sequencing the E6, E2, and L1 regions. Four hundred twenty-five samples were positive for the HC2 test, 31.5% from CSW/IPW and 10.7% from the general population. HPV16 was the most frequent type. Distinct profiles of oncogenic HPV type prevalence were observed across the two populations. In order of decreasing frequency, HPV types 16, 31, 58, 66, 56, and 18 were most frequent in CSW/IPW women, and types 16, 31, 52, 68, 51, and 53 were most frequent in the general population. We analyzed HPV16 intratype variants, and a large majority (78.7%) belonged to the European lineage. AA variants were detected in 16.0% of cases. African variants belonging to classes Af1 (4.0%) and Af2 (1.3%) were detected. Different HPV types and HPV16 intratype variants are involved in oncogenic HPV infections in our population. These results suggest that HPV type distribution differs in CSW/IPW women and in the general population, although further analysis is necessary. PMID:16597872

  1. The Beginning Spanish Lexicon: A Web-based interface to calculate phonological similarity among Spanish words in adults learning Spanish as a foreign language

    PubMed Central

    Vitevitch, Michael S.; Stamer, Melissa K.; Kieweg, Douglas

    2013-01-01

    A number of resources provide psycholinguistic researchers with information about the words that the typical child or adult knows in a variety of languages. What is currently not available is a resource that provides information about the words that a typical adult learning a foreign language knows. We created such a resource for Spanish: The Beginning Spanish Lexicon. The present report describes the words contained in this web-accessible resource, and the information about those words provided by the interface. This information is freely accessible at: http://www.people.ku.edu/~mvitevit/BegSpanLex.html PMID:25342870

  2. The Beginning Spanish Lexicon: A Web-based interface to calculate phonological similarity among Spanish words in adults learning Spanish as a foreign language.

    PubMed

    Vitevitch, Michael S; Stamer, Melissa K; Kieweg, Douglas

    2012-01-01

    A number of resources provide psycholinguistic researchers with information about the words that the typical child or adult knows in a variety of languages. What is currently not available is a resource that provides information about the words that a typical adult learning a foreign language knows. We created such a resource for Spanish: The Beginning Spanish Lexicon. The present report describes the words contained in this web-accessible resource, and the information about those words provided by the interface. This information is freely accessible at: http://www.people.ku.edu/~mvitevit/BegSpanLex.html.

  3. Cloning and characterization of two duplicated interleukin-17A/F2 genes in common carp (Cyprinus carpio L.): Transcripts expression and bioactivity of recombinant IL-17A/F2.

    PubMed

    Li, Hongxia; Yu, Juhua; Li, Jianlin; Tang, Yongkai; Yu, Fan; Zhou, Jie; Yu, Wenjuan

    2016-04-01

    Interleukin-17 (IL-17) plays an important role in inflammation and host defense in mammals. In this study, we identified two duplicated IL-17A/F2 genes in the common carp (Cyprinus carpio) (ccIL-17A/F2a and ccIL-17A/F2b), putative encoded proteins contain 140 amino acids (aa) with conserved IL-17 family motifs. Expression analysis revealed high constitutive expression of ccIL-17A/F2s in mucosal tissues, including gill, skin and intestine, their expression could be induced by Aeromonas hydrophila, suggesting a potential role in mucosal immunity. Recombinant ccIL-17A/F2a protein (rccIL-17A/F2a) produced in Escherichia coli could induce the expression of proinflammatory cytokines (IL-1β) and the antimicrobial peptides S100A1, S100A10a and S100A10b in the primary kidney in a dose- and time-dependent manner. Above findings suggest that ccIL-17A/F2 plays an important role in both proinflammatory and innate immunity. Two duplicated ccIL-17A/F2s showed different expression level with ccIL-17A/F2a higher than b, comparison of two 5' regulatory regions indicated the length from anticipated promoter to transcriptional start site (TSS) and putative transcription factor binding site (TFBS) were different. Promoter activity of ccIL-17A/F2a was 2.5 times of ccIL-17A/F2b which consistent with expression results of two genes. These suggest mutations in 5'regulatory region contributed to the differentiation of duplicated genes. To our knowledge, this is the first report to analyze 5'regulatory region of piscine IL-17 family genes. PMID:26921542

  4. Internet Abuse Risk Factors among Spanish Adolescents.

    PubMed

    Carballo, José L; Marín-Vila, María; Espada, José P; Orgilés, Mireia; Piqueras, José A

    2015-11-27

    Empirical evidence has revealed various factors that contribute to the development and maintenance of Internet abuse. The aim of this paper was to analyze, on a sample of Spanish adolescents, the relationship between Internet abuse and: (1) Personal and interpersonal risk factors, including social skills in both virtual and real-life contexts; (2) Drug use. A total of 814 high school students aged between 13 and 17 participated in this study, and were divided into two groups: Internet Abusers (IA = 173) and Non-Internet Abusers (NIA = 641). Questionnaires were used to analyze Internet and drug use/abuse, as well as social skills, in virtual and real contexts. Various interpersonal risk factors (family and group of friends) were also assessed. IA showed a more severe pattern of Internet and drug use, as well as poorer social skills in both contexts. Moreover, their groups of friends appeared more likely to become involved in risky situations related to Internet and drug abuse. Both IA and NIA showed more adaptive social skills in the virtual context than in the real one. There is a need for further research to build on these findings, with a view to designing specific preventive programs that promote responsible Internet use.

  5. Haematuria on the Spanish Registry of Glomerulonephritis.

    PubMed

    Yuste, Claudia; Rivera, Francisco; Moreno, Juan Antonio; López-Gómez, Juan Manuel

    2016-01-01

    Recent studies suggest a pathogenic role for glomerular haematuria among renal function. However, there is no data on the prevalence of haematuria from a large renal biopsy registry. We analysed the prevalence of gross (GH) and microscopic (mH) haematuria in 19,895 patients that underwent native renal biopsies from the Spanish Registry of Glomerulonephritis. Haematuria's overall incidence was 63% (GH 8.6% and mH 55.1%), being more frequent in males (64.7% vs. 62.4%). GH was more prevalent in patients <18 years (21.3% vs. 7.7%). The commonest clinical presentation associated with GH was acute kidney injury (31.5%) and IgA Nephropathy (IgAN) (33.6%) was the most frequent histological finding. GH patients showed a significantly (p < 0.05) lower eGFR and proteinuria levels as compared with patients with mH and without haematuria. Moreover, mH was more prevalent in adults (56.3%). Nephrotic syndrome was the commonest clinical presentation in mH patients (32.2%) and IgAN (18.5%) the most frequent histological finding. In conclusion, haematuria, is a frequent urinalysis finding in patients underwent native renal biopsy. The most frequent histological finding in both GH and mH is IgAN. Whereas, GH is more frequent in young males with acute kidney injury, mH is commoner among adults with nephrotic syndrome. PMID:26818712

  6. Reading strategies in Spanish developmental dyslexics.

    PubMed

    Suárez-Coalla, Paz; Cuetos, Fernando

    2012-07-01

    Cross-linguistic studies suggest that the orthographic system determines the reading performance of dyslexic children. In opaque orthographies, the fundamental feature of developmental dyslexia is difficulty in reading accuracy, whereas slower reading speed is more common in transparent orthographies. The aim of the current study was to examine the extent to which different variables of words affect reaction times and articulation times in developmental dyslexics. A group of 19 developmental dyslexics of different ages and an age-matched group of 19 children without reading disabilities completed a word naming task. The children were asked to read 100 nouns that differed in length, frequency, age of acquisition, imageability, and orthographic neighborhood. The stimuli were presented on a laptop computer, and the responses were recorded using DMDX software. We conducted analyses of mixed-effects models to determine which variables influenced reading times in dyslexic children. We found that word naming skills in dyslexic children are affected predominantly by length, while in non-dyslexics children the principal variable is the age of acquisition, a lexical variable. These findings suggest that Spanish-speaking developmental dyslexics use a sublexical procedure for reading words, which is reflected in slower speed when reading long words. In contrast, normal children use a lexical strategy, which is frequently observed in readers of opaque languages.

  7. Haematuria on the Spanish Registry of Glomerulonephritis

    PubMed Central

    Yuste, Claudia; Rivera, Francisco; Moreno, Juan Antonio; López-Gómez, Juan Manuel

    2016-01-01

    Recent studies suggest a pathogenic role for glomerular haematuria among renal function. However, there is no data on the prevalence of haematuria from a large renal biopsy registry. We analysed the prevalence of gross (GH) and microscopic (mH) haematuria in 19,895 patients that underwent native renal biopsies from the Spanish Registry of Glomerulonephritis. Haematuria’s overall incidence was 63% (GH 8.6% and mH 55.1%), being more frequent in males (64.7% vs. 62.4%). GH was more prevalent in patients <18 years (21.3% vs. 7.7%). The commonest clinical presentation associated with GH was acute kidney injury (31.5%) and IgA Nephropathy (IgAN) (33.6%) was the most frequent histological finding. GH patients showed a significantly (p < 0.05) lower eGFR and proteinuria levels as compared with patients with mH and without haematuria. Moreover, mH was more prevalent in adults (56.3%). Nephrotic syndrome was the commonest clinical presentation in mH patients (32.2%) and IgAN (18.5%) the most frequent histological finding. In conclusion, haematuria, is a frequent urinalysis finding in patients underwent native renal biopsy. The most frequent histological finding in both GH and mH is IgAN. Whereas, GH is more frequent in young males with acute kidney injury, mH is commoner among adults with nephrotic syndrome. PMID:26818712

  8. Spanish cabinet moves to liberalize abortion law.

    PubMed

    1995-07-14

    On July 7 (1995), the cabinet of Spain's socialist prime minister Felipe Gonzalez approved a measure to expand the country's abortion law by permitting a woman to obtain the procedure during the first 12 weeks of pregnancy in circumstances not currently allowed. Since 1985, abortion has been legal throughout pregnancy in the following situations: when a medical specialist not associated with the procedure determines that an abortion is necessary to "avert a serious risk to [a woman's] physical or mental health;" during the first 12 weeks if the pregnancy results from reported rape; and within the first 22 weeks when two physicians not associated with the abortion certify that the fetus would develop "severe physical or mental defects." The new legislation, which also requires women to receive nonbinding counseling, permits abortions when a health care professional determines that carrying to term will cause a woman severe anxiety for social or economic reasons. Before the measure can become law, it must be approved by the Spanish Parliament, which is expected to vote on the proposal in September. The Catalan nationalist grouping, which has been a key supporter of the socialist government, is among the forces opposing liberalization of the abortion statute. Partly due to the abortion controversy, the Catalan coalition is expected to vote on July 17 to decide whether to continue its backing.

  9. Modeling spall in HY100, HY130, and AF1410 steels

    NASA Astrophysics Data System (ADS)

    Garrett, R. K.; Rajendran, A. M.; Last, H. R.

    1996-05-01

    A comparison spall analysis between three matensitic steels: HY100, HY130, and AF1410 is presented Metallurgical observations on the fracture surfaces of uniaxial tensile specimens as well as the spalled target plates confirmed the nucleation, growth, and coalescence of microvoids in these steels. The threshold stress for void nucleation in these steels were determined from the spall analysis using the EPIC finite element code. According to the model, the spall nucleation occurred at higher stress levels in AF1410 compared to HY100 and HY130. A complete set of material model constants has been determined for these three steels.

  10. 27. "SITE PLAN." Specifications No. OC15775, Drawing No. AF600915, sheet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. "SITE PLAN." Specifications No. OC1-57-75, Drawing No. AF-60-09-15, sheet 1 of 96, D.O. Series No. AF 1394/20, Rev. B. Stamped: RECORD DRAWING - AS CONSTRUCTED. Below stamp: Contract no. 5296 Rev. B, Date: 11/17/59. Site plan of 20,000-foot track, including construction phasing notes. - Edwards Air Force Base, South Base Sled Track, Edwards Air Force Base, North of Avenue B, between 100th & 140th Streets East, Lancaster, Los Angeles County, CA

  11. The splicing factor U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis

    SciTech Connect

    Kim, Jeonghee; Chung, In Kwon

    2014-01-17

    Highlights: •Identification of U2AF65 as a novel TRF1-interacting protein. •U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis. •U2AF65 interferes with the interaction between TRF1 and Fbx4. •U2AF65 represents a new route for modulating TRF1 function at telomeres. -- Abstract: The human telomeric protein TRF1 is a component of the six-subunit protein complex shelterin, which provides telomere protection by organizing the telomere into a high-order structure. TRF1 functions as a negative regulator of telomere length by controlling the access of telomerase to telomeres. Thus, the cellular abundance of TRF1 at telomeres should be maintained and tightly regulated to ensure proper telomere function. Here, we identify U2 small nuclear ribonucleoprotein (snRNP) auxiliary factor 65 (U2AF65), an essential pre-mRNA splicing factor, as a novel TRF1-interacting protein. U2AF65 interacts with TRF1 in vitro and in vivo and is capable of stabilizing TRF1 protein by inhibiting its ubiquitin-dependent proteolysis. We also found that U2AF65 interferes with the interaction between TRF1 and Fbx4, an E3 ubiquitin ligase for TRF1. Depletion of endogenous U2AF65 expression by short interfering RNA (siRNA) reduced the stability of endogenous TRF1 whereas overexpression of U2AF65 significantly extended the half-life of TRF1. These findings demonstrate that U2AF65 plays a critical role in regulating the level of TRF1 through physical interaction and ubiquitin-mediated proteolysis. Hence, U2AF65 represents a new route for modulating TRF1 function at telomeres.

  12. Metaphoric Reference: An Eye Movement Analysis of Spanish-English and English-Spanish Bilingual Readers.

    PubMed

    Heredia, Roberto R; Cieślicka, Anna B

    2016-01-01

    This study examines the processing of metaphoric reference by bilingual speakers. English dominant, Spanish dominant, and balanced bilinguals read passages in English biasing either a figurative (e.g., describing a weak and soft fighter that always lost and everyone hated) or a literal (e.g., describing a donut and bakery shop that made delicious pastries) meaning of a critical metaphoric referential description (e.g., "creampuff"). We recorded the eye movements (first fixation, gaze duration, go-past duration, and total reading time) for the critical region, which was a metaphoric referential description in each passage. The results revealed that literal vs. figurative meaning activation was modulated by language dominance, where Spanish dominant bilinguals were more likely to access the literal meaning, and English dominant and balanced bilinguals had access to both the literal and figurative meanings of the metaphoric referential description. Overall, there was a general tendency for the literal interpretation to be more active, as revealed by shorter reading times for the metaphoric reference used literally, in comparison to when it was used figuratively. Results are interpreted in terms of the Graded Salience Hypothesis (Giora, 2002, 2003) and the Literal Salience Model (Cieślicka, 2006, 2015).

  13. Metaphoric Reference: An Eye Movement Analysis of Spanish-English and English-Spanish Bilingual Readers.

    PubMed

    Heredia, Roberto R; Cieślicka, Anna B

    2016-01-01

    This study examines the processing of metaphoric reference by bilingual speakers. English dominant, Spanish dominant, and balanced bilinguals read passages in English biasing either a figurative (e.g., describing a weak and soft fighter that always lost and everyone hated) or a literal (e.g., describing a donut and bakery shop that made delicious pastries) meaning of a critical metaphoric referential description (e.g., "creampuff"). We recorded the eye movements (first fixation, gaze duration, go-past duration, and total reading time) for the critical region, which was a metaphoric referential description in each passage. The results revealed that literal vs. figurative meaning activation was modulated by language dominance, where Spanish dominant bilinguals were more likely to access the literal meaning, and English dominant and balanced bilinguals had access to both the literal and figurative meanings of the metaphoric referential description. Overall, there was a general tendency for the literal interpretation to be more active, as revealed by shorter reading times for the metaphoric reference used literally, in comparison to when it was used figuratively. Results are interpreted in terms of the Graded Salience Hypothesis (Giora, 2002, 2003) and the Literal Salience Model (Cieślicka, 2006, 2015). PMID:27065911

  14. Short Assessment of Health Literacy—Spanish and English: A Comparable Test of Health Literacy for Spanish and English Speakers

    PubMed Central

    Lee, Shoou-Yih Daniel; Stucky, Brian D; Lee, Jessica Y; Rozier, R Gary; Bender, Deborah E

    2010-01-01

    Objective The intent of the study was to develop and validate a comparable health literacy test for Spanish-speaking and English-speaking populations. Study Design The design of the instrument, named the Short Assessment of Health Literacy—Spanish and English (SAHL-S&E), combined a word recognition test, as appearing in the Rapid Estimate of Adult Literacy in Medicine (REALM), and a comprehension test using multiple-choice questions designed by an expert panel. We used the item response theory (IRT) in developing and validating the instrument. Data Collection Validation of SAHL-S&E involved testing and comparing the instrument with other health literacy instruments in a sample of 201 Spanish-speaking and 202 English-speaking subjects recruited from the Ambulatory Care Center at the University of North Carolina Healthcare System. Principal Findings Based on IRT analysis, 18 items were retained in the comparable test. The Spanish version of the test, SAHL-S, was highly correlated with other Spanish health literacy instruments, Short Assessment of Health Literacy for Spanish-Speaking Adults (r=0.88, p<.05) and the Spanish Test of Functional Health Literacy in Adults (TOFHLA) (r=0.62, p<.05). The English version, SAHL-E, had high correlations with REALM (r=0.94, p<.05) and the English TOFHLA (r=0.68, p<.05). Significant correlations were found between SAHL-S&E and years of schooling in both Spanish- and English-speaking samples (r=0.15 and 0.39, respectively). SAHL-S&E displayed satisfactory reliability of 0.80 and 0.89 in the Spanish- and English-speaking samples, respectively. IRT analysis indicated that the SAHL-S&E score was highly reliable for individuals with a low level of health literacy. Conclusions The new instrument, SAHL-S&E, has good reliability and validity. It is particularly useful for identifying individuals with low health literacy and could be used to screen for low health literacy among Spanish and English speakers. PMID:20500222

  15. Short Research Note: The Beginning Spanish Lexicon--A Web-Based Interface to Calculate Phonological Similarity among Spanish Words in Adults Learning Spanish as a Foreign Language

    ERIC Educational Resources Information Center

    Vitevitch, Michael S.; Stamer, Melissa K.; Kieweg, Douglas

    2012-01-01

    A number of resources provide psycholinguistic researchers with information about the words that the typical child or adult knows in a variety of languages. What is currently not available is a resource that provides information about the words that a typical adult learning a foreign language knows. We created such a resource for Spanish: The…

  16. Rangelands management in Spanish Natura 2000 sites.

    NASA Astrophysics Data System (ADS)

    Hernando Gallego, A.; Tejera Gimeno, R.; Velázquez Saornil, J.; Núñez Martí, V.; Grande Vega, M.

    2009-04-01

    Spanish open oak woodlands have had multiple land uses such as firewood extraction and grazing through centuries. Consequently, 20% of the Spanish forest is coppice forest. This particular agrosilvopastoral system is well widespread in the southern and western part of the Iberian Peninsula. As a result of the implementation of Natura 2000 in Spain, many of these habitats have been included in this network listed as "Dehesas" with evergreen Quercus spp. (Sclerophyllous grazed forests -dehesas-). The main goal of Natura 2000 is assuring "favourable conservation status" of natural habitats and species within these areas (Habitats Directive 92/43/ECC). This is the case of the study area, "Dehesa Boyal" (Ávila), which management plan has been carried out in a public forest land. The current situation is a degraded coppice forest, Quercus pyrenaica and Q.ilex, with a shrub encroachment due to previous firewood extraction. Besides, problems such as soil compaction and lack of sexual have been observed presumably related with livestock (180 horses, 1100 goats, 900 sheeps and 190 cows distributed in different seasons). Livestock feed on the acorns and hedge young sprouts making them sprouting again. The shrub encroachment is far from "conservation status" required in Natura 2000. Furthermore, the livestock cannot be removed because it is an important part of this agrosilvopastoral system not only for the landscape but also for its economic importance to local owners. Management plans should consider all of these circumstances and propose an integrated approach. To achieve this goal, the area was accurately classified in age classes by "stands" (oak shrubland, low pole stages, coppice tall shrub and sapling) in each habitat, using Geographic Information Systems (G.I.S), remote sensing techniques and detailed field work. Then, the "conservation status" of each stand is classified in A (Favourable), B (Inconvenient) and C (Unfavourable conservation status) considering some

  17. Anthropometric Characteristics of Spanish Professional Basketball Players.

    PubMed

    Alejandro, Vaquera; Santiago, Santos; Gerardo, Villa José; Carlos, Morante Juan; Vicente, García-Tormo

    2015-06-27

    The study of elite basketball players' anthropometric characteristics alongside those of body composition contributes significantly to their profiling as professional athletes and plays an important role in the selection process, as these characteristics can have a significant impact on performance. In the current study, 110 professional basketball players from a series of Spanish professional Leagues (ACB, LEB and EBA) and youth level National Teams (U20 and U18) had their anthropometric profiles measured and compared to determine differences between them. Furthermore, all 110 players were divided into three different categories according to their playing position: guards, forwards and centres. The results obtained show no significant differences between players in different competitions in weight, height and the sum of skinfolds. Nonetheless, there were several differences related to body fat content (13.03% in ACB players and 10.52% in the lower categories and National Teams). There were also several differences found between the different playing positions amongst all playing levels in body mass (79.56 ± 2.41, 91.04 ± 1.51 and 104.56 ± 1.73 kg), height (182.28 ± 0.96, 195.65 ± 1.00 and 204.08 ± 0.67 cm), skinfold distribution and perimeters. However, there were no significant differences in body fat content between the different playing positions. The conclusions obtained from this study provide a better understanding to basketball specialists regarding the selection process of players at the elite level, especially on the transition from youth elite programs to men's elite leagues. PMID:26240653

  18. Anthropometric Characteristics of Spanish Professional Basketball Players

    PubMed Central

    Alejandro, Vaquera; Santiago, Santos; Gerardo, Villa José; Carlos, Morante Juan; Vicente, García-Tormo

    2015-01-01

    The study of elite basketball players’ anthropometric characteristics alongside those of body composition contributes significantly to their profiling as professional athletes and plays an important role in the selection process, as these characteristics can have a significant impact on performance. In the current study, 110 professional basketball players from a series of Spanish professional Leagues (ACB, LEB and EBA) and youth level National Teams (U20 and U18) had their anthropometric profiles measured and compared to determine differences between them. Furthermore, all 110 players were divided into three different categories according to their playing position: guards, forwards and centres. The results obtained show no significant differences between players in different competitions in weight, height and the sum of skinfolds. Nonetheless, there were several differences related to body fat content (13.03% in ACB players and 10.52% in the lower categories and National Teams). There were also several differences found between the different playing positions amongst all playing levels in body mass (79.56 ± 2.41, 91.04 ± 1.51 and 104.56 ± 1.73 kg), height (182.28 ± 0.96, 195.65 ± 1.00 and 204.08 ± 0.67 cm), skinfold distribution and perimeters. However, there were no significant differences in body fat content between the different playing positions. The conclusions obtained from this study provide a better understanding to basketball specialists regarding the selection process of players at the elite level, especially on the transition from youth elite programs to men’s elite leagues. PMID:26240653

  19. Anthropometric Characteristics of Spanish Professional Basketball Players.

    PubMed

    Alejandro, Vaquera; Santiago, Santos; Gerardo, Villa José; Carlos, Morante Juan; Vicente, García-Tormo

    2015-06-27

    The study of elite basketball players' anthropometric characteristics alongside those of body composition contributes significantly to their profiling as professional athletes and plays an important role in the selection process, as these characteristics can have a significant impact on performance. In the current study, 110 professional basketball players from a series of Spanish professional Leagues (ACB, LEB and EBA) and youth level National Teams (U20 and U18) had their anthropometric profiles measured and compared to determine differences between them. Furthermore, all 110 players were divided into three different categories according to their playing position: guards, forwards and centres. The results obtained show no significant differences between players in different competitions in weight, height and the sum of skinfolds. Nonetheless, there were several differences related to body fat content (13.03% in ACB players and 10.52% in the lower categories and National Teams). There were also several differences found between the different playing positions amongst all playing levels in body mass (79.56 ± 2.41, 91.04 ± 1.51 and 104.56 ± 1.73 kg), height (182.28 ± 0.96, 195.65 ± 1.00 and 204.08 ± 0.67 cm), skinfold distribution and perimeters. However, there were no significant differences in body fat content between the different playing positions. The conclusions obtained from this study provide a better understanding to basketball specialists regarding the selection process of players at the elite level, especially on the transition from youth elite programs to men's elite leagues.

  20. (/sup 3/H)AF-DX 116 labels subsets of muscarinic cholinergic receptors in rat brain and heart

    SciTech Connect

    Wang, J.X.; Roeske, W.R.; Gulya, K.; Wang, W.; Yamamura, H.I.

    1987-10-05

    The in vitro binding properties of the novel muscarinic antagonist (/sup 3/H)AF-DX 116 were studied using a rapid filtration technique. Association and dissociation rates of (/sup 3/H)AF-DX 116 binding were rapid at 25/sup 0/C but 20-40 times slower at 0-4/sup 0/C. Kinetic dissociation constants (K/sub d/s) were estimated to be 31.8 nM and 30.9 nM at 25/sup 0/C; 23.1 nM and 22.9 nM at 0-4/sup 0/C for the cerebral cortex and heart, respectively. In saturation studies, (/sup 3/H)AF-DX 116 labeled 29% of the total (/sup 3/H)(-)QNB binding sites in the cerebral cortical membranes and 87% in the cardiac membranes, with K/sub d/ values of 28.9 nM and 17.9 nM, respectively. Muscarinic antagonists inhibited (/sup 3/H)AF-DX 116 binding in a rank order of potency of atropine > dexetimide > AF-DX 116 > PZ > levetimide in both tissues. Except for PZ/(/sup 3/H)AF-DX 116 and AF-DX 116/(/sup 3/H)AF-DX 116 in the cerebral cortex, all the antagonist competition curves had Hill coefficients close to one. 19 references, 2 figures, 4 tables.

  1. Draft Genome Sequence of Komagataeibacter intermedius Strain AF2, a Producer of Cellulose, Isolated from Kombucha Tea.

    PubMed

    Dos Santos, Renato Augusto Corrêa; Berretta, Andresa Aparecida; Barud, Hernane da Silva; Ribeiro, Sidney José Lima; González-García, Laura Natalia; Zucchi, Tiago Domingues; Goldman, Gustavo H; Riaño-Pachón, Diego M

    2015-12-03

    Here, we present the draft genome sequence of Komagataeibacter intermedius strain AF2, which was isolated from Kombucha tea and is capable of producing cellulose, although at lower levels compared to another bacterium from the same environment, K. rhaeticus strain AF1.

  2. Identification and Characterization of an Antifungal Protein, AfAFPR9, Produced by Marine-Derived Aspergillus fumigatus R9.

    PubMed

    Rao, Qi; Guo, Wenbin; Chen, Xinhua

    2015-05-01

    A fungal strain, R9, was isolated from the South Atlantic sediment sample and identified as Aspergillus fumigatus. An antifungal protein, AfAFPR9, was purified from the culture supernatant of Aspergillus fumigatus R9. AfAFPR9 was identified to be restrictocin, which is a member of the ribosome-inactivating proteins (RIPs), by MALDI-TOF-TOF-MS. AfAFPR9 displayed antifungal activity against plant pathogenic Fusarium oxysporum, Alternaria longipes, Colletotrichum gloeosporioides, Paecilomyces variotii, and Trichoderma viride at minimum inhibitory concentrations of 0.6, 0.6, 1.2, 1.2, and 2.4 μg/disc, respectively. Moreover, AfAFPR9 exhibited a certain extent of thermostability, and metal ion and denaturant tolerance. The iodoacetamide assay showed that the disulfide bridge in AfAFPR9 was indispensable for its antifungal action. The cDNA encoding for AfAFPR9 was cloned from A. fumigatus R9 by RTPCR and heterologously expressed in E. coli. The recombinant AfAFPR9 protein exhibited obvious antifungal activity against C. gloeosporioides, T. viride, and A. longipes. These results reveal the antifungal properties of a RIP member (AfAFPR9) from marine-derived Aspergillus fumigatus and indicated its potential application in controlling plant pathogenic fungi. PMID:25394604

  3. Genome Sequence of Anoxybacillus thermarum AF/04T, Isolated from the Euganean Hot Springs in Abano Terme, Italy.

    PubMed

    Poli, Annarita; Nicolaus, Barbara; Chan, Kok-Gan; Kahar, Ummirul Mukminin; Chan, Chia Sing; Goh, Kian Mau

    2015-05-21

    Anoxybacillus thermarum AF/04(T) was isolated from the Euganean hot springs in Abano Terme, Italy. The present work reports a high-quality draft genome sequence of strain AF/04(T). This work also provides useful insights into glycoside hydrolases, glycoside transferases, and sugar transporters that may be involved in cellular carbohydrate metabolism.

  4. Draft Genome Sequence of Komagataeibacter intermedius Strain AF2, a Producer of Cellulose, Isolated from Kombucha Tea

    PubMed Central

    dos Santos, Renato Augusto Corrêa; Berretta, Andresa Aparecida; Barud, Hernane da Silva; Ribeiro, Sidney José Lima; González-García, Laura Natalia; Zucchi, Tiago Domingues

    2015-01-01

    Here, we present the draft genome sequence of Komagataeibacter intermedius strain AF2, which was isolated from Kombucha tea and is capable of producing cellulose, although at lower levels compared to another bacterium from the same environment, K. rhaeticus strain AF1. PMID:26634755

  5. Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis.

    PubMed

    Kakeda, M; Schlapbach, Christoph; Danelon, G; Tang, M M; Cecchinato, V; Yawalkar, N; Uguccioni, M

    2014-12-01

    Acute generalized exanthematous pustulosis (AGEP) and generalized pustular psoriasis (GPP) are rare pustular skin disorders with systemic involvement. IL-17A/F is a proinflammatory cytokine involved in various neutrophilic inflammatory disorders. Here we show that IL-17A/F is highly expressed by innate immune cells such as neutrophils and mast cells in both AGEP and GPP.

  6. Abusive head trauma in Spanish language medical literature.

    PubMed

    Cooper, M Townsend; Szyld, Edgardo; Darden, Paul M

    2016-08-01

    Anecdotal experiences raise concerns that abusive head trauma (AHT) is significantly underdiagnosed and perhaps poorly recognized in Latin American settings. With increasing interest in international collaboration in pediatrics, differences in perspectives regarding complex diagnoses should be explored to facilitate a productive exchange of knowledge and ideas. The purpose of this study was to describe the medical literature pertaining to AHT available to physicians who read only in Spanish. In this review, LILACS, SciELO (major Spanish language databases) and Pubmed were searched with appropriate terms and filters in English, Spanish, and Portuguese for Spanish language articles on AHT. Identified articles' reference lists were then examined for possible additional articles on AHT. All relevant articles were sorted by country and examined for article type and content. Thirty-four unique articles were located for review from 8 of 21 countries. Most of the articles identified were case reports, case series, or educational, and there were no studies regarding overall incidence or prevalence of AHT. Some scientific information contained in the articles varied considerably from that in the English language literature in the areas of etiology and preventive strategies. This survey highlights that the Spanish language literature regarding AHT is sparse and variable. This must be considered when working collaboratively in a global setting. Additionally, identification of this gap presents an opportunity for education and information exchange among global medical communities. PMID:27434224

  7. Abusive head trauma in Spanish language medical literature.

    PubMed

    Cooper, M Townsend; Szyld, Edgardo; Darden, Paul M

    2016-08-01

    Anecdotal experiences raise concerns that abusive head trauma (AHT) is significantly underdiagnosed and perhaps poorly recognized in Latin American settings. With increasing interest in international collaboration in pediatrics, differences in perspectives regarding complex diagnoses should be explored to facilitate a productive exchange of knowledge and ideas. The purpose of this study was to describe the medical literature pertaining to AHT available to physicians who read only in Spanish. In this review, LILACS, SciELO (major Spanish language databases) and Pubmed were searched with appropriate terms and filters in English, Spanish, and Portuguese for Spanish language articles on AHT. Identified articles' reference lists were then examined for possible additional articles on AHT. All relevant articles were sorted by country and examined for article type and content. Thirty-four unique articles were located for review from 8 of 21 countries. Most of the articles identified were case reports, case series, or educational, and there were no studies regarding overall incidence or prevalence of AHT. Some scientific information contained in the articles varied considerably from that in the English language literature in the areas of etiology and preventive strategies. This survey highlights that the Spanish language literature regarding AHT is sparse and variable. This must be considered when working collaboratively in a global setting. Additionally, identification of this gap presents an opportunity for education and information exchange among global medical communities.

  8. How Readable are Spanish-Language Medicaid Applications?

    PubMed Central

    Hansen, Julie S.; DeVoe, Jennifer E.

    2015-01-01

    Nationally, Hispanics comprise nearly one-quarter of all non-elderly Medicaid recipients. We evaluated readability, layout characteristics, and document complexity of state-issued Spanish-language Medicaid enrollment applications. We located and analyzed Internet-based Spanish enrollment applications from 37 states and the District of Columbia. We calculated the readability of each Medicaid enrollment application “Signature” page using the Spanish Lexile Analyzer. We assessed application layout characteristics utilizing the User-Friendliness Tool, and we evaluated document complexity using the PMOSE/IKIRSCH scale. The average Lexile score estimated an 11th–12th grade reading level (M = 1184, SD = 192) for “Signature” pages of enrollment applications. Most applications used small font size and lacked adequate white space. Document complexity ranged from level 3 (moderate) to level 5 (very high); the majority of applications ranked at level 4 (high). Spanish-language Medicaid enrollment applications should be revised to adhere to low-literacy guidelines, which may improve the accessibility of Medicaid coverage for eligible Spanish-speaking families. PMID:21213122

  9. AfsR as an integrator of signals that are sensed by multiple serine/threonine kinases in Streptomyces coelicolor A3(2).

    PubMed

    Horinouchi, Sueharu

    2003-08-01

    The genome sequence of Streptomyces coelicolor A3(2) has revealed the presence of about 40 protein serine/threonine or tyrosine kinases. AfsK, which is able to phosphorylate AfsR, a transcriptional activator with ATPase activity, represents the first instance in which a bacterial Hanks-type protein kinase phosphorylates a specific protein and exerts biologically important functions. The AfsK-AfsR system in S. coelicolor A3(2) globally controls secondary metabolism. The signal transduction pathway so far demonstrated or suggested is as follows: AfsK loosely attached to the membrane autophosphorylates threonine and serine residues, perhaps on sensing some external stimulus, and enhances its kinase activity. The kinase activity is modulated by KbpA, an AfsK-binding protein, by means of protein-protein interactions. The activated AfsK phosphorylates threonine and serine residues of AfsR in the cytoplasm, by which the DNA-binding activity of AfsR is greatly enhanced. In addition to AfsK, other kinases-including PkaG and AfsL-also phosphorylate AfsR, suggesting that AfsR serves as an integrator of multiple signals sensed by these kinases. The phosphorylated AfsR binds the promoter of afsS, which encodes a protein of 63 amino acids, and forms a closed complex with RNA polymerase. The closed complex is then converted to a transcriptionally active open complex by the energy available from ATP hydrolysis by AfsR. AfsS induced in this way activates transcription of pathway-specific transcriptional activators, such as actII-ORF4 for actinorhodin production and redD for undecylprodigiosin, in an as yet unknown manner.

  10. A Spanish Language and Culture Initiative for a Doctor of Pharmacy Curriculum

    PubMed Central

    Kennedy, Gala; Vance, Michael A.; Hancock, Bruce

    2011-01-01

    Objective To implement a Spanish language and culture initiative in a doctor of pharmacy (PharmD) curriculum that would improve students' Spanish language skills and cultural competence so that graduates could provide competent pharmaceutical care to Spanish-speaking patients. Design Five elective courses were created and introduced to the curriculum including 2 medical Spanish courses; a medical Spanish service-learning course; a 2-week Spanish language and cultural immersion trip to Mexico; and an advanced practice pharmacy experience (APPE) at a medical care clinic serving a high percentage of Spanish-speaking patients. Advisors placed increased emphasis on encouraging pharmacy students to complete a major or minor in Spanish. Assessment Enrollment in the Spanish language courses and the cultural immersion trip has been strong. Twenty-three students have completed the APPE at a Spanish-speaking clinic. Eleven percent of 2010 Butler University pharmacy graduates completed a major or minor in Spanish compared to approximately 1% in 2004 when the initiative began. Conclusion A Spanish language and culture initiative started in 2004 has resulted in increased Spanish language and cultural competence among pharmacy students and recent graduates. PMID:21451756

  11. Unusual hydrogen bonding patterns in AF (aminofluorene) and AAF (acetylaminofluorene) modified DNA

    SciTech Connect

    Broyde, S.; Hingerty, B.E.; Shapiro, R.; Norman, D.

    1989-01-01

    New structures are presented for AF and AAF modified DNAs that place the carcinogen in the minor groove of a B-DNA helix. These structures employ non-Watson-Crick base pairing schemes with syn guanine at the modification site. 32 refs., 9 figs.

  12. First report of an infant botulism case due to Clostridium botulinum type Af.

    PubMed

    de Jong, Laura I T; Fernández, Rafael A; Pareja, Virtudes; Giaroli, Gabriel; Guidarelli, Sergio R; Dykes, Janet K; Lúquez, Carolina

    2015-02-01

    Most infant botulism cases worldwide are due to botulinum toxin types A and B. Rarely, Clostridium botulinum strains that produce two serotypes (Ab, Ba, and Bf) have also been isolated from infant botulism cases. This is the first reported case of infant botulism due to C. botulinum type Af worldwide.

  13. K-theory of the chair tiling via AF-algebras

    NASA Astrophysics Data System (ADS)

    Julien, Antoine; Savinien, Jean

    2016-08-01

    We compute the K-theory groups of the groupoid C∗-algebra of the chair tiling, using a new method. We use exact sequences of Putnam to compute these groups from the K-theory groups of the AF-algebras of the substitution and the induced lower dimensional substitutions on edges and vertices.

  14. 40 CFR 180.1206 - Aspergillus flavus AF36; exemption from the requirement of a tolerance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... tolerance is established for residues of Aspergillus flavus AF36 in or on corn, field, forage; corn, field, grain; corn, field, stover; corn, field, aspirated grain fractions; corn, sweet, kernel plus cob with husk removed; corn, sweet, forage; corn, sweet, stover; corn, pop, grain; and corn, pop, stover,...

  15. 40 CFR 180.1206 - Aspergillus flavus AF36; exemption from the requirement of a tolerance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... tolerance is established for residues of Aspergillus flavus AF36 in or on corn, field, forage; corn, field, grain; corn, field, stover; corn, field, aspirated grain fractions; corn, sweet, kernel plus cob with husk removed; corn, sweet, forage; corn, sweet, stover; corn, pop, grain; and corn, pop, stover,...

  16. 40 CFR 180.1206 - Aspergillus flavus AF36; exemption from the requirement of a tolerance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... tolerance is established for residues of Aspergillus flavus AF36 in or on corn, field, forage; corn, field, grain; corn, field, stover; corn, field, aspirated grain fractions; corn, sweet, kernel plus cob with husk removed; corn, sweet, forage; corn, sweet, stover; corn, pop, grain; and corn, pop, stover,...

  17. Fracture Mechanics Testing of Titanium 6AL-4V in AF-M315E

    NASA Technical Reports Server (NTRS)

    Sampson, J. W.; Martinez, J.; McLean, C.

    2016-01-01

    The Green Propellant Infusion Mission (GPIM) will demonstrate the performance of AF-M315E monopropellant on orbit. Flight certification requires a safe-life analysis of the titanium alloy fuel tank to ensure inherent processing flaws will not cause failure during the design life of the tank. Material property inputs for this analysis require testing to determine the stress intensity factor for environment-assisted cracking (KEAC) of Ti 6Al-4V in combination with the AF-M315E monopropellant. Testing of single-edge notched, or SE(B), specimens representing the bulk tank membrane and weld material were performed in accordance with ASTM E1681. Specimens with fatigue pre-cracks were loaded into test fixtures so that the crack tips were exposed to AF-M315E at 50 C for a duration of 1,000 hours. Specimens that did not fail during exposure were opened to inspect the crack surfaces for evidence of crack growth. The threshold stress intensity value, KEAC, is the highest applied stress intensity that produced neither a failure of the specimen during the exposure nor showed evidence of crack growth. The threshold stress intensity factor for environment-assisted cracking of the Ti 6Al-4V forged tank material was found to be at least 22 ksivin and at least 31 ksivin for the weld material when exposed to AF-M315E monopropellant.

  18. Developing an Assessment for Learning (AfL) Culture in School: The Voice of the Principals

    ERIC Educational Resources Information Center

    Smith, Kari; Engelsen, Knut Steinar

    2013-01-01

    This study reflects the voice of school leaders (principals) in a Norwegian school development project focusing on assessment for learning (AfL). The central role of the principal in school improvement is well documented, however, less is written about how the principals themselves see their roles. The voices presented belong to two experienced…

  19. Acutangulosides A-F, monodesmosidic saponins from the bark of Barringtonia acutangula.

    PubMed

    Mills, Clive; Carroll, Anthony R; Quinn, Ronald J

    2005-03-01

    Nine triterpene saponins, acutangulosides A-F (2-7), and acutanguloside D-F methyl esters (5a-7a) and a single triterpene aglycone (1) were isolated from a water extract of the bark of Barringtonia acutangula. Their structures were assigned on the basis of spectroscopic data. PMID:15787427

  20. 28. Site Plan: AF Station P67, Fort Custer, Michigan, Plot ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Site Plan: AF Station P-67, Fort Custer, Michigan, Plot Plan (to accompany FY 1956 project planning report), USACOE, 22 July 1954. - Fort Custer Military Reservation, P-67 Radar Station, .25 mile north of Dickman Road, east of Clark Road, Battle Creek, Calhoun County, MI

  1. POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.

    PubMed

    Zhou, Haixia; Brekman, Angelika; Zuo, Wu-Lin; Ou, Xuemei; Shaykhiev, Renat; Agosto-Perez, Francisco J; Wang, Rui; Walters, Matthew S; Salit, Jacqueline; Strulovici-Barel, Yael; Staudt, Michelle R; Kaner, Robert J; Mezey, Jason G; Crystal, Ronald G; Wang, Guoqing

    2016-04-01

    In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU domain class 2-associating factor 1 (POU2AF1), a known transcription cofactor previously thought to be expressed only in lymphocytes. Lymphocyte contamination of human airway epithelial samples obtained by bronchoscopy and brushing was excluded by immunohistochemistry staining, the observation of upregulation of POU2AF1 in purified airway basal stem/progenitor cells undergoing differentiation, and analysis of differentiating single basal cell clones. Lentivirus-mediated upregulation of POU2AF1 in airway basal cells induced upregulation of host defense genes, including MX1, IFIT3, IFITM, and known POU2AF1 downstream genes HLA-DRA, ID2, ID3, IL6, and BCL6. Interestingly, expression of these genes paralleled changes of POU2AF1 expression during airway epithelium differentiation in vitro, suggesting POU2AF1 helps to maintain a host defense tone even in pathogen-free condition. Cigarette smoke, a known risk factor for airway infection, suppressed POU2AF1 expression both in vivo in humans and in vitro in human airway epithelial cultures, accompanied by deregulation of POU2AF1 downstream genes. Finally, enhancing POU2AF1 expression in human airway epithelium attenuated the suppression of host defense genes by smoking. Together, these findings suggest a novel function of POU2AF1 as a potential regulator of host defense genes in the human airway epithelium. PMID:26927796

  2. POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.

    PubMed

    Zhou, Haixia; Brekman, Angelika; Zuo, Wu-Lin; Ou, Xuemei; Shaykhiev, Renat; Agosto-Perez, Francisco J; Wang, Rui; Walters, Matthew S; Salit, Jacqueline; Strulovici-Barel, Yael; Staudt, Michelle R; Kaner, Robert J; Mezey, Jason G; Crystal, Ronald G; Wang, Guoqing

    2016-04-01

    In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU domain class 2-associating factor 1 (POU2AF1), a known transcription cofactor previously thought to be expressed only in lymphocytes. Lymphocyte contamination of human airway epithelial samples obtained by bronchoscopy and brushing was excluded by immunohistochemistry staining, the observation of upregulation of POU2AF1 in purified airway basal stem/progenitor cells undergoing differentiation, and analysis of differentiating single basal cell clones. Lentivirus-mediated upregulation of POU2AF1 in airway basal cells induced upregulation of host defense genes, including MX1, IFIT3, IFITM, and known POU2AF1 downstream genes HLA-DRA, ID2, ID3, IL6, and BCL6. Interestingly, expression of these genes paralleled changes of POU2AF1 expression during airway epithelium differentiation in vitro, suggesting POU2AF1 helps to maintain a host defense tone even in pathogen-free condition. Cigarette smoke, a known risk factor for airway infection, suppressed POU2AF1 expression both in vivo in humans and in vitro in human airway epithelial cultures, accompanied by deregulation of POU2AF1 downstream genes. Finally, enhancing POU2AF1 expression in human airway epithelium attenuated the suppression of host defense genes by smoking. Together, these findings suggest a novel function of POU2AF1 as a potential regulator of host defense genes in the human airway epithelium.

  3. The presence of English and Spanish dyslexia in the Web

    NASA Astrophysics Data System (ADS)

    Rello, Luz; Baeza-Yates, Ricardo

    2012-09-01

    In this study we present a lower bound of the prevalence of dyslexia in the Web for English and Spanish. On the basis of analysis of corpora written by dyslexic people, we propose a classification of the different kinds of dyslexic errors. A representative data set of dyslexic words is used to calculate this lower bound in web pages containing English and Spanish dyslexic errors. We also present an analysis of dyslexic errors in major Internet domains, social media sites, and throughout English- and Spanish-speaking countries. To show the independence of our estimations from the presence of other kinds of errors, we compare them with the overall lexical quality of the Web and with the error rate of noncorrected corpora. The presence of dyslexic errors in the Web motivates work in web accessibility for dyslexic users.

  4. Total PCBs and PCB congeners in Spanish Imperial Eagle eggs

    SciTech Connect

    Hernandez, L.M.; Fernandez, M.A.; Gonzalez, M.J. )

    1989-11-01

    The Spanish Imperial Eagle Aquila (heliaca) adalberti is the only directly endangered bird of prey in Europe. Lowered reproductive success in numerous bird species has been associated with eggshell thinning and reduced production caused by DDE, the most common organochlorine residue found in wild birds. Polychlorinated biphenyls (PCBs) are usually the second most common organochlorine pollutant found in wild birds. Research to evaluate the incidence of organochlorine pollutants in the Spanish Imperial Eagle has been previously conducted. The authors have now determined the levels of total PCBs and selected PCB congeners in 34 eggs of Spanish Imperial Eagle collected at Donana National Park, Castile Plateau and Nature Park of Monfrague, since this has considerable significance when attempts are made to correlate the embryonic mortality of avian wildlife with PCB residue levels.

  5. [Spanish adaptation of Hobfoll's Strategic Approach to Coping Scale (SACS)].

    PubMed

    Pedrero Pérez, Eduardo J; Santed Germán, Miguel A; Pérez García, Ana M

    2012-01-01

    The present research adapted the Strategic Approach to Coping Scale (SACS), developed by Hobfoll and colleagues, to the Spanish population. SACS is an instrument derived from Hobfoll's Conservation of Resources Theory, which emphasises the contribution of social factors to coping processes. This instrument assesses coping strategies in 9-subscales, organised in three dimensions: orientation to the problem (active/passive), use of social resources (prosocial/antisocial), and orientation to others involved (direct/indirect). The Spanish version, administered to a non-clinical sample (N= 767), found 7-subscales structured in prosocial/antisocial, active/passive and reflexive/intuitive dimensions, with adequate reliability and construct validity. To conclude, the Spanish SACS is a potentially useful and reliable instrument for research and clinical purposes, mainly in areas in which social components need to be explicitly considered.

  6. Sexual compulsivity scale: adaptation and validation in the spanish population.

    PubMed

    Ballester-Arnal, Rafael; Gómez-Martínez, Sandra; Llario, M Dolores-Gil; Salmerón-Sánchez, Pedro

    2013-01-01

    Sexual compulsivity has been studied in relation to high-risk behavior for sexually transmitted infections. The aim of this study was the adaptation and validation of the Sexual Compulsivity Scale to a sample of Spanish young people. This scale was applied to 1,196 (891 female, 305 male) Spanish college students. The results of principal components factor analysis using a varimax rotation indicated a two-factor solution. The reliability of the Sexual Compulsivity Scale was found to be high. Moreover, the scale showed good temporal stability. External correlates were examined through Pearson correlations between the Sexual Compulsivity Scale and other constructs related with HIV prevention. The authors' results suggest that the Sexual Compulsivity Scale is an appropriate measure for assessing sexual compulsivity, showing adequate psychometric properties in the Spanish population.

  7. The Challenges and Rewards of Teaching Spanish in a Community College Prison Program

    ERIC Educational Resources Information Center

    Palomino, Erick Nava; Ragsdale, Lee

    2015-01-01

    Two authors describe how teaching Spanish in an Illinois prison led them to rewrite the examples used in a Spanish textbook and engage incarcerated students in novel ways in order to make up for the lack of conventional classroom resources.

  8. Los Ninos y el Mundo: Children's Books in Spanish from around the World.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2001-01-01

    Offers brief descriptions of 32 children's books (or book series) in Spanish that introduce children to numerous countries around the world. Notes a web site address listing high-quality books in Spanish for children and adolescents. (SR)

  9. Two Words of Chinese Origin in Present-Day Peruvian Spanish

    ERIC Educational Resources Information Center

    Horton, James F.

    1977-01-01

    The origin, etymology and phonology of two words of Chinese origin found in Peruvian Spanish are outlined. The words, "chifa" and "chaufa," derive from Cantonese words for "rice" and have been adapted into Spanish. (CHK)

  10. Informe sobre el proyecto contrastivo hispano-hungaro (Report on the Spanish-Hungarian Contrastive Project)

    ERIC Educational Resources Information Center

    Fulei-Szanto, Andres

    1974-01-01

    A description of a contrastive linguistics project in Hungary aiming to augment linguistic theories in the Spanish language and propound theories for scientific and artistic translation. (Text is in Spanish.) (CK)

  11. Equalization characteristics of an upflow sludge blanket-aerated biofilter (USB-AF) system.

    PubMed

    Jun, H B; Park, S M; Park, J K; Lee, S H

    2005-01-01

    Equalization characteristics of the upflow sludge blanket-aerated bio-filter (USB-AF) were investigated with the fluctuated raw domestic sewage. Recycle of nitrified effluent from AF to USB triggered the equalization characteristics of the sludge blanket on both soluble and particulate organic matter. Increment of EPS in sludge blanket by nitrate recycle was detected and removal of turbidity and particulates increased at higher recycle ratios by bio-flocculation. Increased TCOD removal in the USB was due to both denitrification of recycled nitrate and entrapment of the particulate organic matter in sludge blanket. Capture of both soluble and particulate organic matter increased sludge blanket layer in the USB, which improved the reactor performances and reduced the organic load on the subsequent AF. Overall TCOD and SS removal efficiencies were about 98% and 96%, respectively in the USB-AF system. Turbidity in the USB effluent was about 44, 20 and 5.5 NTU, at recycle ratios of 0, 100 and 200%, respectively. Particle counts in the range 2-4 microm in the USB effluent were higher than those in influent without nitrate recycle, while particle counts in the range of 0.5-15 microm in the USB effluent decreased 70% at recycle ratio of 200%. The major constituent of EPS extracted from anaerobic sludge was protein and total EPS increased from 109.1 to 165.7 mg/g-VSS with nitrate recycle of 100%. Removal efficiency and concentration of T-N in the UBS-AF effluent was over 70% and below 16 mg/L, respectively.

  12. TYPE AF CERTIFICATE FOR TRANSPORTATION OF LOW ENRICHED URANIUM OXIDE (LEUO) FOR DISPOSAL

    SciTech Connect

    Opperman, E; Kenneth Yates, K

    2007-10-19

    Washington Savannah River Company (WSRC) operates the Savannah River Site (SRS) in Aiken, SC under contract with the U.S. Department of Energy (DOE). SRS had the need to ship 227 drums of low enriched uranium oxide (LEUO) to a disposal site. The LEUO had been packaged nearly 25 years ago in U.S. Department of Transportation (DOT) 17C 55-gallon drums and stored in a warehouse. Since the 235U enrichment was just above 1 percent by weight (wt%) the material did not qualify for the fissile material exceptions in 49 CFR 173.453, and therefore was categorized as 'fissile material' for shipping purposes. WSRC evaluated all existing Type AF packages and did not identify any feasible packaging. Applying for a new Type AF certificate of compliance was considered too costly for a one-time/one-way shipment for disposal. Down-blending the material with depleted uranium (to reduce enrichment below 1 wt% and enable shipment as low specific activity (LSA) radioactive material) was considered, but appropriate blending facilities do not exist at SRS. After reviewing all options, WSRC concluded that seeking a DOT Special Permit was the best option to enable shipment of the material for permanent disposal. WSRC submitted the Special Permit application to the DOT, and after one request-for-additional-information (RAI) the permit was considered acceptable. However, in an interesting development that resulted from the DOT Special Permit application process, it was determined that it was more appropriate for the DOE to issue a Type AF certificate [Ref. 1] for this shipping campaign. This paper will outline the DOT Special Permit application and Type AF considerations, and will discuss the issuance of the new DOE Type AF certificate of compliance.

  13. Spanish validation of the HIV dementia scale in women.

    PubMed

    Wojna, V; Skolasky, R L; McArthur, J C; Maldonado, E; Hechavarria, R; Mayo, R; Selnes, O; Ginebra, T; de la Torre, T; Garcia, H; Kraiselburd, E; Melendez-Guerrero, L M; Zorrilla, C D; Nath, A

    2007-12-01

    HIV infection is increasing in minority groups, particularly in African American and Hispanic women. Although the incidence of HIV dementia has decreased since the advent of highly active antiretroviral treatment, prevalence of neurocognitive complications has increased as patients are now living longer. This study's purpose was to determine the psychometric properties of the Spanish-language HIV Dementia Scale (HDS) in a group of HIV-infected women. We recruited 96 women: 60 HIV-seropositive and 36 HIV-seronegative. Modification of the HDS into a Spanish-language version consisted of translating the instructions, substituting four words in Spanish (gato, media, azul, piña), increasing 1 second in the psychomotor speed because the Spanish alphabet has more letters than the English alphabet, and not offering clues for memory recall. Cognitive impairment (CI) was defined according to the modified American Academy of Neurology HIV-dementia criteria including an asymptomatic CI group. Statistical analysis consisted of analysis of variance to determine group differences and receiver operator characteristics (ROC) to determine the optimal cutoff point for the screening of CI. HDS-Spanish total score and subscores for psychomotor speed and memory recall showed significant differences between HIV-seronegative and women with HIV-dementia (p < 0.001) and between HIV-seropositive women with normal cognition and those with HIV-dementia (p < 0.001). The optimal cutoff point of 13 or less had performance characteristics of 87% sensitivity and 46% specificity for HIV-associated CI (50.0% positive predictive value, 85.0% negative predictive value). The HDS-Spanish translation offers a useful screening tool with value for the identification of Hispanic women at risk of developing HIV-associated symptomatic neurocognitive disturbances. PMID:18154490

  14. Satisfaction With Provider Communication Among Spanish-Speaking Medicaid Enrollees

    PubMed Central

    Mosen, David M.; Carlson, Matthew J.; Morales, Leo S.; Hanes, Pamela P.

    2006-01-01

    Objective To determine if differences between English- and Spanish-speaking parents in ratings of their children’s health care can be explained by need for interpretive services. Methods Using the Consumer Assessment of Health Plans Survey–Child-Survey (CAHPS), reports about provider communication were compared among 3 groups of parents enrolled in a Medicaid managed care health plan: 1) English speakers, 2) Spanish speakers with no self-reported need for interpretive services, and 3) Spanish speakers with self-reported need for interpretive services. Parents were asked to report how well their providers 1) listened carefully to what was being said, 2) explained things in a way that could be understood, 3) respected their comments and concerns, and 4) spent enough time during medical encounters. Multivariate logistic regression was used to compare the ratings of each of the 3 groups while controlling for child’s gender, parent’s gender, parent’s educational attainment, child’s health status, and survey year. Results Spanish-speaking parents in need of interpretive services were less likely to report that providers spent enough time with their children (odds ratio = 0.34, 95% confidence interval = 0.17–0.68) compared to English-speaking parents. There was no statistically significant difference found between Spanish-speaking parents with no need of interpretive services and English-speaking parents. Conclusions Among Spanish- versus English-speaking parents, differences in ratings of whether providers spent enough time with children during medical encounters appear to be explained, in part, by need for interpretive services. No other differences in ratings of provider communication were found. PMID:15548101

  15. 7 CFR 51.2730 - U.S. No. 1 Spanish.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Spanish. 51.2730 Section 51.2730... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2730 U.S. No. 1 Spanish. “U.S. No. 1 Spanish” consists of shelled Spanish type peanut kernels which are whole and...

  16. 7 CFR 51.2732 - U.S. No. 2 Spanish.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Spanish. 51.2732 Section 51.2732... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2732 U.S. No. 2 Spanish. “U.S. No. 2 Spanish” consists of shelled Spanish type peanut kernels which may be split or...

  17. Psychometric properties of Spanish-language adult dental fear measures

    PubMed Central

    Coolidge, Trilby; Chambers, Mark A; Garcia, Laura J; Heaton, Lisa J; Coldwell, Susan E

    2008-01-01

    Background It would be useful to have psychometrically-sound measures of dental fear for Hispanics, who comprise the largest ethnic minority in the United States. We report on the psychometric properties of Spanish-language versions of two common adult measures of dental fear (Modified Dental Anxiety Scale, MDAS; Dental Fear Survey, DFS), as well as a measure of fear of dental injections (Needle Survey, NS). Methods Spanish versions of the measures were administered to 213 adults attending Hispanic cultural festivals, 31 students (who took the questionnaire twice, for test-retest reliability), and 100 patients at a dental clinic. We also administered the questionnaire to 136 English-speaking adults at the Hispanic festivals and 58 English-speaking students at the same college where we recruited the Spanish-speaking students, to compare the performance of the English and Spanish measures in the same populations. Results The internal reliabilities of the Spanish MDAS ranged from 0.80 to 0.85. Values for the DFS ranged from 0.92 to 0.96, and values for the NS ranged from 0.92 to 0.94. The test-retest reliabilities (intra-class correlations) for the three measures were 0.69, 0.86, and 0.94 for the MDAS, DFS, and NS, respectively. The three measures showed moderate correlations with one another in all three samples, providing evidence for construct validity. Patients with higher scores on the measures were rated as being more anxious during dental procedures. Similar internal reliabilities and correlations were found in the English-version analyses. The test-retest values were also similar in the English students for the DFS and NS; however, the English test-retest value for the MDAS was better than that found in the Spanish students. Conclusion We found evidence for the internal reliability, construct validity, and criterion validity for the Spanish versions of the three measures, and evidence for the test-retest reliability of the Spanish versions of the DFS and NS

  18. The Spanish standard patch test series: 2016 update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC).

    PubMed

    Hervella-Garcés, M; García-Gavín, J; Silvestre-Salvador, J F

    2016-09-01

    The Spanish standard patch test series, as recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC), has been updated for 2016. The new series replaces the 2012 version and contains the minimum set of allergens recommended for routine investigation of contact allergy in Spain from 2016 onwards. Four haptens -clioquinol, thimerosal, mercury, and primin- have been eliminated owing to a low frequency of relevant allergic reactions, while 3 new allergens -methylisothiazolinone, diazolidinyl urea, and imidazolidinyl urea- have been added. GEIDAC has also modified the recommended aqueous solution concentrations for the 2 classic, major haptens methylchloroisothiazolinone and methylisothiazolinone, which are now to be tested at 200ppm in aqueous solution, and formaldehyde, which is now to be tested in a 2% aqueous solution. Updating the Spanish standard series is one of the functions of GEIDAC, which is responsible for ensuring that the standard series is suited to the country's epidemiological profile and pattern of contact sensitization.

  19. Student Voices: The Missing Link in the Spanish Heritage Language Debate

    ERIC Educational Resources Information Center

    Ducar, Cynthia M.

    2008-01-01

    Though much of the research looking at the issue of language in the Spanish heritage language field is intended to guide the Spanish heritage language teacher in the classroom, students' voices are often stifled. This article fills this gap by giving voice to students' opinions on language use in the Spanish heritage language classroom. Survey…

  20. Receptive Volitional Subjunctive Abilities in Heritage and Traditional Foreign Language Learners of Spanish

    ERIC Educational Resources Information Center

    Mikulski, Ariana M.

    2010-01-01

    The Spanish subjunctive has been known to pose difficulties for learners of Spanish whose native language is English (e.g., Collentine, 1997, 2003; Terrell, Baycroft, & Perrone, 1987). Investigating the same feature in heritage learners of Spanish can provide more information about the linguistic development of this growing population. This pilot…