Science.gov

Sample records for affect small governments

  1. Does Privatization Affect Access to Government Information?

    ERIC Educational Resources Information Center

    Caponio, Joseph F.; Geffner, Janet

    This paper begins by pointing out that privatization, or relying on the private sector to provide commercial goods and services for government departments and agencies, is a tool that has been used effectively by the federal government for several decades. It then presents the theoretical basis for privatization, describes a number of methods used…

  2. 76 FR 43571 - Small Business HUBZone Program; Government Contracting Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Part 126 RIN 3245-AG45 Small Business HUBZone Program; Government Contracting Programs... investment and assist the Federal government in meeting its statutory prime contracting HUBZone goal of...

  3. Affect and Engagement during Small Group Instruction

    ERIC Educational Resources Information Center

    Linnenbrink-Garcia, Lisa; Rogat, Toni Kempler; Koskey, Kristin L. K.

    2011-01-01

    Two studies (Study 1: n = 137; Study 2: n = 192) were conducted to investigate how upper-elementary students' affect during small group instruction related to their social-behavioral engagement during group work. A circumplex model of affect consisting of valence (positive, negative) and activation (high, low) was used to examine the relation of…

  4. Small agricultural impoundments affect pollutant transport

    NASA Astrophysics Data System (ADS)

    Balcerak, Ernie

    2013-03-01

    Reservoirs created by dams intercept runoff from upslope areas and thus are often sinks for fertilizers and other pollutants that would otherwise flow downstream. Most studies of solute transport through impoundments have focused on large, long-lived systems. However, small impoundments, such as those created for irrigation or livestock watering, are common in agricultural regions, and their total global surface area is comparable to that of large reservoirs. As these small systems mature, the impoundments fill with sediment, creating ecosystems with wetland-like characteristics. Because dams that create these small impoundments are more likely to be degraded, poorly maintained, or removed by their owners, it is important to understand how changes in such systems may affect pollutant transport.

  5. Fiscal Stress in Wisconsin Small Governments: Indicators and Responses.

    ERIC Educational Resources Information Center

    Wolensky, Robert P.; Enright, Robert B.

    1991-01-01

    Surveyed 59 Wisconsin officials to determine the fiscal crises in U.S. small towns. Results did not reveal a fiscal crisis, but fiscal stress was evident. Wisconsin small governments responded to fiscal stress though increasing local taxes, borrowing money, obtaining increased state aid and shared revenue, reducing expenditures, and promoting…

  6. Irrelevant events affect voters' evaluations of government performance.

    PubMed

    Healy, Andrew J; Malhotra, Neil; Mo, Cecilia Hyunjung

    2010-07-20

    Does information irrelevant to government performance affect voting behavior? If so, how does this help us understand the mechanisms underlying voters' retrospective assessments of candidates' performance in office? To precisely test for the effects of irrelevant information, we explore the electoral impact of local college football games just before an election, irrelevant events that government has nothing to do with and for which no government response would be expected. We find that a win in the 10 d before Election Day causes the incumbent to receive an additional 1.61 percentage points of the vote in Senate, gubernatorial, and presidential elections, with the effect being larger for teams with stronger fan support. In addition to conducting placebo tests based on postelection games, we demonstrate these effects by using the betting market's estimate of a team's probability of winning the game before it occurs to isolate the surprise component of game outcomes. We corroborate these aggregate-level results with a survey that we conducted during the 2009 NCAA men's college basketball tournament, where we find that surprising wins and losses affect presidential approval. An experiment embedded within the survey also indicates that personal well-being may influence voting decisions on a subconscious level. We find that making people more aware of the reasons for their current state of mind reduces the effect that irrelevant events have on their opinions. These findings underscore the subtle power of irrelevant events in shaping important real-world decisions and suggest ways in which decision making can be improved. PMID:20615955

  7. Irrelevant events affect voters' evaluations of government performance

    PubMed Central

    Healy, Andrew J.; Malhotra, Neil; Mo, Cecilia Hyunjung

    2010-01-01

    Does information irrelevant to government performance affect voting behavior? If so, how does this help us understand the mechanisms underlying voters’ retrospective assessments of candidates’ performance in office? To precisely test for the effects of irrelevant information, we explore the electoral impact of local college football games just before an election, irrelevant events that government has nothing to do with and for which no government response would be expected. We find that a win in the 10 d before Election Day causes the incumbent to receive an additional 1.61 percentage points of the vote in Senate, gubernatorial, and presidential elections, with the effect being larger for teams with stronger fan support. In addition to conducting placebo tests based on postelection games, we demonstrate these effects by using the betting market's estimate of a team's probability of winning the game before it occurs to isolate the surprise component of game outcomes. We corroborate these aggregate-level results with a survey that we conducted during the 2009 NCAA men's college basketball tournament, where we find that surprising wins and losses affect presidential approval. An experiment embedded within the survey also indicates that personal well-being may influence voting decisions on a subconscious level. We find that making people more aware of the reasons for their current state of mind reduces the effect that irrelevant events have on their opinions. These findings underscore the subtle power of irrelevant events in shaping important real-world decisions and suggest ways in which decision making can be improved. PMID:20615955

  8. Irrelevant events affect voters' evaluations of government performance.

    PubMed

    Healy, Andrew J; Malhotra, Neil; Mo, Cecilia Hyunjung

    2010-07-20

    Does information irrelevant to government performance affect voting behavior? If so, how does this help us understand the mechanisms underlying voters' retrospective assessments of candidates' performance in office? To precisely test for the effects of irrelevant information, we explore the electoral impact of local college football games just before an election, irrelevant events that government has nothing to do with and for which no government response would be expected. We find that a win in the 10 d before Election Day causes the incumbent to receive an additional 1.61 percentage points of the vote in Senate, gubernatorial, and presidential elections, with the effect being larger for teams with stronger fan support. In addition to conducting placebo tests based on postelection games, we demonstrate these effects by using the betting market's estimate of a team's probability of winning the game before it occurs to isolate the surprise component of game outcomes. We corroborate these aggregate-level results with a survey that we conducted during the 2009 NCAA men's college basketball tournament, where we find that surprising wins and losses affect presidential approval. An experiment embedded within the survey also indicates that personal well-being may influence voting decisions on a subconscious level. We find that making people more aware of the reasons for their current state of mind reduces the effect that irrelevant events have on their opinions. These findings underscore the subtle power of irrelevant events in shaping important real-world decisions and suggest ways in which decision making can be improved.

  9. 76 FR 18757 - Monthly Public Meetings of the Local Government Advisory Committee's Small Community Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... AGENCY Monthly Public Meetings of the Local Government Advisory Committee's Small Community Advisory... Advisory Committee Act, the U.S. Environmental Protection Agency's Local Government Advisory Committee's... the Local Government Advisory Committee. BILLING CODE 6560-50-P...

  10. 13 CFR 126.101 - Which government departments or agencies are affected directly by the HUBZone program?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Which government departments or agencies are affected directly by the HUBZone program? 126.101 Section 126.101 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Provisions of General Applicability § 126.101...

  11. 77 FR 2539 - Meetings of the Small Communities Advisory Subcommittee and the Local Government Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... if the number of requests for appearances requires it. The Local Government Advisory Committee (LGAC... requests for appearances requires it. Dates and Addresses: The Small Communities Advisory...

  12. An Examination of the Utilization of Electronic Government Services by Minority Small Businesses

    ERIC Educational Resources Information Center

    Ford, Wendy G.

    2010-01-01

    There are a wide variety of e-government information and services that small business owners and managers can utilize. However, in spite of all of the service incentives and initiatives to promote e-government, research studies have shown that this information is not widely accessed. Studies that explore the utilization of e-government information…

  13. 76 FR 35891 - Meeting of the Local Government Advisory Committee and Small Community Advisory Subcommittee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... AGENCY Meeting of the Local Government Advisory Committee and Small Community Advisory Subcommittee AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The U.S. EPA's Local Government...., Chicago, Illinois. FOR FURTHER INFORMATION CONTACT: Paula Zampieri, DFO for the Local Government...

  14. New Community Governance in Small Rural Towns: The Australian Experience

    ERIC Educational Resources Information Center

    O'Toole, Kevin; Burdess, Neil

    2004-01-01

    State and federal governments in Australia have developed a range of policy instruments for rural areas in Australia that are infused with a new sense of "community," employing leading concepts like social capital, social enterprise, community development, partnerships and community building. This has encouraged local people and organisations to…

  15. Legal factors affecting the financing of small scale hydroelectric projects

    SciTech Connect

    Wilson, W.H.; Ringo, M.J.; Forgione, N.

    1983-09-01

    An introduction to the major business organizational options open to small-scale hydroelectric (SSH) projects is given. The major federal income tax treatments of these options are compared. Significant general federal income tax factors affecting SSH projects are reintroduced and explained. Some of the special federal income tax problem areas in SSH development are isolated. Tax benefit flow through or transfer mechanisms are discussed. Tax exempt financing opportunities for private SSH projects are reviewed. (MHR)

  16. How health affects small business in South Africa.

    PubMed

    Chao, Li-Wei; Pauly, Mark V

    2007-03-01

    Preventable and treatable diseases have taken a devastating human and economic toll on many developing countries. That economic toll is likely to be underestimated because most studies focus on productivity losses in the formal, or large-firm, sector; yet, a large portion of the population of developing countries works in the informal sector in very small businesses, either as an owner-worker or as an employee. It is plausible that ill health might affect small businesses most severely, possibly putting the entire business at risk. This Issue Brief summarizes a three-year study that tracks small businesses in Durban, South Africa, and investigates the connection between the owner's health and business growth, survival, or closure. The results bolster the economic case for investing resources in the prevention and treatment of disease in developing countries. PMID:17458036

  17. 42 CFR 137.445 - Will an immediate reassumption appeal adversely affect the Self-Governance Tribe's rights in...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... affect the Self-Governance Tribe's rights in other self-governance negotiations? 137.445 Section 137.445..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Appeals Appeals of An Immediate Reassumption of A Self-Governance Program § 137.445 Will an immediate reassumption appeal adversely affect...

  18. 42 CFR 137.445 - Will an immediate reassumption appeal adversely affect the Self-Governance Tribe's rights in...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... affect the Self-Governance Tribe's rights in other self-governance negotiations? 137.445 Section 137.445..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Appeals Appeals of An Immediate Reassumption of A Self-Governance Program § 137.445 Will an immediate reassumption appeal adversely affect...

  19. 42 CFR 137.445 - Will an immediate reassumption appeal adversely affect the Self-Governance Tribe's rights in...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... affect the Self-Governance Tribe's rights in other self-governance negotiations? 137.445 Section 137.445..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Appeals Appeals of An Immediate Reassumption of A Self-Governance Program § 137.445 Will an immediate reassumption appeal adversely affect...

  20. 42 CFR 137.445 - Will an immediate reassumption appeal adversely affect the Self-Governance Tribe's rights in...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... affect the Self-Governance Tribe's rights in other self-governance negotiations? 137.445 Section 137.445..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Appeals Appeals of An Immediate Reassumption of A Self-Governance Program § 137.445 Will an immediate reassumption appeal adversely affect...

  1. 42 CFR 137.445 - Will an immediate reassumption appeal adversely affect the Self-Governance Tribe's rights in...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... affect the Self-Governance Tribe's rights in other self-governance negotiations? 137.445 Section 137.445..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Appeals Appeals of An Immediate Reassumption of A Self-Governance Program § 137.445 Will an immediate reassumption appeal adversely affect...

  2. Can small shifts in circadian phase affect performance?

    PubMed Central

    Burgess, Helen J.; Legasto, Carlo S.; Fogg, Louis F.; Smith, Mark R.

    2012-01-01

    Small shifts in circadian timing occur frequently as a result of daylight saving time or later weekend sleep. These subtle shifts in circadian phase have been shown to influence subjective sleepiness, but it remains unclear if they can significantly affect performance. In a retrospective analysis we examined performance on the Psychomotor Vigilance Test before bedtime and after wake time in 11 healthy adults on fixed sleep schedules based on their habitual sleep times. The dim light melatonin onset, a marker of circadian timing, was measured on two occasions. An average 1.1 hour shift away from a proposed optimal circadian phase angle (6 hours between melatonin onset and midpoint of sleep) significantly slowed mean, median and fastest 10% reaction times before bedtime and after wake time (p<0.05). These results add to previous reports that suggest that humans may be sensitive to commonly occurring small shifts in circadian timing. PMID:22695081

  3. Corridors and olfactory predator cues affect small mammal behavior.

    SciTech Connect

    Brinkerhoff, Robert Jory; Haddad, Nick M.; Orrock, John L.

    2005-03-30

    Abstract The behavior of prey individuals is influenced by a variety of factors including, but not limited to, habitat configuration, risk of predation, and availability of resources, and these habitat-dependent factors may have interactive effects. We studied the responses of mice to an increase in perceived predation risk in a patchy environment to understand how habitat corridors might affect interactions among species in a fragmented landscape. We used a replicated experiment to investigate corridor-mediated prey responses to predator cues in a network of open habitat patches surrounded by a matrix of planted pine forest. Some of the patches were connected by corridors. We used mark–recapture techniques and foraging trays to monitor the movement, behavior, and abundance of small mammals. Predation threat was manipulated in one-half of the replicates by applying an olfactory predator cue. Corridors synchronized small mammal foraging activity among connected patches. Foraging also was inhibited in the presence of an olfactory predator cue but apparently increased in adjacent connected patches. Small mammal abundance did not change as a result of the predator manipulation and was not influenced by the presence of corridors. This study is among the 1st to indicate combined effects of landscape configuration and predation risk on prey behavior. These changes in prey behavior may, in turn, have cascading effects on community dynamics where corridors and differential predation risk influence movement and patch use.

  4. IT Governance Practices in Small and Medium-Sized Enterprises: Recommendations from an Empirical Study

    NASA Astrophysics Data System (ADS)

    Huang, Rui; Zmud, Robert W.; Price, R. Leon

    Much has been learned through IT governance research about the nature of IT-related decisions, the location of decision rights for these decisions, and governance mechanisms applied to facilitate associated decision processes in large organisations. Our knowledge about IT governance structures in small and medium-sized enterprises (SME), on the other hand, is quite limited. Adopting a qualitative and inductive approach, this study examines the nature and influence of IT governance in SMEs through interviews with executives from three SMEs. Our results demonstrate that IT decision authority was centralized in all three SMEs but that senior management involvement in governance procedures and communication practices about governance policies were observed to explain differences in these organisations’ IT use. We propose recommendations based on the findings of this study.

  5. Does fiscal discipline towards subnational governments affect citizens' well-being? Evidence on health.

    PubMed

    Piacenza, Massimiliano; Turati, Gilberto

    2014-02-01

    This paper aims to assess the impact on citizens' well-being of fiscal discipline imposed by the central government on subnational governments. Because healthcare policies involve strategic interactions between different layers of governments in many different countries, we focus on a particular dimension of well-being, namely citizens' health. We model fiscal discipline by considering government expectations of future deficit bailouts from the central government. We then study how these bailout expectations affect the expenditure for healthcare policies carried out by decentralized governments. To investigate this issue, we separate efficient health spending from inefficiencies by estimating an input requirement frontier. This allows us to assess the effects of bailout expectations on both the structural component of health expenditure and its deviations from the 'best practice'. The evidence from the 15 Italian ordinary statute regions (observed from 1993 to 2006) points out that bailout expectations do not significantly influence the position of the frontier, thus not affecting citizens' health. However, they do appear to exert a remarkable impact on excess spending. PMID:23408583

  6. Scaling up nutrition in fragile and conflict-affected states: the pivotal role of governance.

    PubMed

    Taylor, Sebastian A J; Perez-Ferrer, Carolina; Griffiths, Andrew; Brunner, Eric

    2015-02-01

    Acute and chronic undernutrition undermine conditions for health, stability and socioeconomic development across the developing world. Although fragile and conflict-affected states have some of the highest rates of undernutrition globally, their response to the multilateral 'Scaling Up Nutrition' (SUN) initiative in its first two-year period was ambivalent. The purpose of this research was to investigate factors affecting fragile and conflict-affected states' engagement with SUN, and to examine what differentiated those fragile states that joined SUN in its first phase from those that did not. Drawing on global databases (Unicef, World Bank, UNDP), and qualitative country case studies (Afghanistan, the Democratic Republic of Congo, Sierra Leone, Pakistan and Yemen) we used bivariate logistic regressions and principal component analysis to assess social, economic and political factors across 41 fragile states looking for systematic differences between those that had signed up to SUN before March 2013 (n = 16), and those that had not (n = 25). While prevalence of malnutrition, health system functioning and level of citizen empowerment had little or no impact on a fragile state's likelihood of joining SUN, the quality of governance (QOG) strongly predicted accession. SUN-signatory fragile states scored systematically better on the World Bank's Country Policy and Institutional Assessment (CPIA) and the Worldwide Governance Indicators 'effectiveness of government' indices. We conclude that strengthening governance in fragile states may enhance their engagement with initiatives such as SUN, but also (recognising the potential for endogeneity), that the way aid is structured and delivered in fragile states may be an underlying determinant of whether and how governance in such contexts improves. The research demonstrates that more nuanced analysis of conditions within and among countries classed as 'fragile and conflict-affected' is both possible and necessary if aid

  7. 3 CFR - Making It Easier for America's Small Businesses and America's Exporters To Access Government...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 25, 2011, winning the future in the global economy will require a Government that wisely allocates... competitiveness, innovation, and job growth. If we are to thrive in the global economy, and make America the best... better serve small businesses and exporters. Among other things, agencies shall work together...

  8. 15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Washington, affected Indian tribes, and adjacent county governments. 922.154 Section 922.154 Commerce and... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL MARINE... of Washington, affected Indian tribes, and adjacent county governments. (a) The Director...

  9. 15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Washington, affected Indian tribes, and adjacent county governments. 922.154 Section 922.154 Commerce and... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL MARINE... of Washington, affected Indian tribes, and adjacent county governments. (a) The Director...

  10. 15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Washington, affected Indian tribes, and adjacent county governments. 922.154 Section 922.154 Commerce and... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL MARINE... of Washington, affected Indian tribes, and adjacent county governments. (a) The Director...

  11. 15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Washington, affected Indian tribes, and adjacent county governments. 922.154 Section 922.154 Commerce and... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL MARINE... of Washington, affected Indian tribes, and adjacent county governments. (a) The Director...

  12. 15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Washington, affected Indian tribes, and adjacent county governments. 922.154 Section 922.154 Commerce and... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL MARINE... of Washington, affected Indian tribes, and adjacent county governments. (a) The Director...

  13. Does small scale structure significantly affect cosmological dynamics?

    PubMed

    Adamek, Julian; Clarkson, Chris; Durrer, Ruth; Kunz, Martin

    2015-02-01

    The large-scale homogeneity and isotropy of the Universe is generally thought to imply a well-defined background cosmological model. It may not. Smoothing over structure adds in an extra contribution, transferring power from small scales up to large. Second-order perturbation theory implies that the effect is small, but suggests that formally the perturbation series may not converge. The amplitude of the effect is actually determined by the ratio of the Hubble scales at matter-radiation equality and today-which are entirely unrelated. This implies that a universe with significantly lower temperature today could have significant backreaction from more power on small scales, and so provides the ideal testing ground for understanding backreaction. We investigate this using two different N-body numerical simulations-a 3D Newtonian and a 1D simulation which includes all relevant relativistic effects. We show that while perturbation theory predicts an increasing backreaction as more initial small-scale power is added, in fact the virialization of structure saturates the backreaction effect at the same level independently of the equality scale. This implies that backreaction is a small effect independently of initial conditions. Nevertheless, it may still contribute at the percent level to certain cosmological observables and therefore it cannot be neglected in precision cosmology. PMID:25699430

  14. Does Small Scale Structure Significantly Affect Cosmological Dynamics?

    NASA Astrophysics Data System (ADS)

    Adamek, Julian; Clarkson, Chris; Durrer, Ruth; Kunz, Martin

    2015-02-01

    The large-scale homogeneity and isotropy of the Universe is generally thought to imply a well-defined background cosmological model. It may not. Smoothing over structure adds in an extra contribution, transferring power from small scales up to large. Second-order perturbation theory implies that the effect is small, but suggests that formally the perturbation series may not converge. The amplitude of the effect is actually determined by the ratio of the Hubble scales at matter-radiation equality and today—which are entirely unrelated. This implies that a universe with significantly lower temperature today could have significant backreaction from more power on small scales, and so provides the ideal testing ground for understanding backreaction. We investigate this using two different N -body numerical simulations—a 3D Newtonian and a 1D simulation which includes all relevant relativistic effects. We show that while perturbation theory predicts an increasing backreaction as more initial small-scale power is added, in fact the virialization of structure saturates the backreaction effect at the same level independently of the equality scale. This implies that backreaction is a small effect independently of initial conditions. Nevertheless, it may still contribute at the percent level to certain cosmological observables and therefore it cannot be neglected in precision cosmology.

  15. 78 FR 66929 - Meetings of the Local Government Advisory Committee and the Small Communities Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ....m.-11:30 a.m. (ET). The Subcommittee will discuss small systems waste treatment, water infrastructure, air quality issues and other issues and recommendations regarding environmental issues affecting.... (ET). The Committee will discuss Draft 2014-2018 EPA Strategic Plan, air quality issues,...

  16. Searching for Judy: How Small Mysteries Affect Narrative Processes and Memory

    ERIC Educational Resources Information Center

    Love, Jessica; McKoon, Gail; Gerrig, Richard J.

    2010-01-01

    Current theories of text processing say little about how authors' narrative choices, including the introduction of small mysteries, can affect readers' narrative experiences. Gerrig, Love, and McKoon (2009) provided evidence that 1 type of small mystery--a character introduced without information linking him or her to the story--affects readers'…

  17. 75 FR 33734 - Regulations Affecting Publication of the United States Government Manual

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... transferred to the Office of the Federal Register from the Office of Government Reports within the Bureau of... From the Federal Register Online via the Government Publishing Office #0; #0;Proposed Rules #0... the United States Government Manual AGENCY: Administrative Committee of the Federal Register....

  18. Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors.

    PubMed

    Khan, Danish; McGrath, Kaitlyn R; Dorosheva, Oleksandra; Bankaitis, Vytas A; Tripathi, Ashutosh

    2016-04-01

    Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling. As such, these proteins offer new opportunities for highly selective chemical interference with specific phosphoinositide pathways in cells. The first and best characterized small molecule inhibitors of the yeast PITP, Sec14, are nitrophenyl(4-(2-methoxyphenyl)piperazin-1-yl)methanones (NPPMs), and a hallmark feature of NPPMs is their exquisite targeting specificities for Sec14 relative to other closely related Sec14-like PITPs. Our present understanding of Sec14::NPPM binding interactions is based on computational docking and rational loss-of-function approaches. While those approaches have been informative, we still lack an adequate understanding of the basis for the high selectivity of NPPMs among closely related Sec14-like PITPs. Herein, we describe a Sec14 motif, which we term the VV signature, that contributes significantly to the NPPM sensitivity/resistance of Sec14-like phosphatidylinositol (PtdIns)/phosphatidylcholine (PtdCho) transfer proteins. The data not only reveal previously unappreciated determinants that govern Sec14-like PITP sensitivities to NPPMs, but enable predictions of which Sec14-like PtdIns/PtdCho transfer proteins are likely to be NPPM resistant or sensitive based on primary sequence considerations. Finally, the data provide independent evidence in support of previous studies highlighting the importance of Sec14 residue Ser173 in the mechanism by which NPPMs engage and inhibit Sec14-like PITPs.

  19. 76 FR 6311 - Regulations Affecting Publication of the United States Government Manual

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-04

    ... distributed to the general public and to officials of the Federal government in a print edition. 75 FR 33734... asked if any smart phone applications related to the Manual were under development and suggested that... Committee is not aware of any applications for smart phones currently under development. We hope that...

  20. E-Democracy and E-Government: How Will These Affect Libraries?

    ERIC Educational Resources Information Center

    Pare, Richard

    In the late 1980s, when few Canadian citizens had Internet access, federal departments and agencies in Canada were already preparing for the future by putting information and documentation online. This paper outlines several government-sponsored programs--SchoolNet, the Canadian Investment Fund, Community Access Program, Canada Foundation for…

  1. Effectiveness of Government's Occupational Skills Development Strategies for Small- and Medium-Scale Enterprises: A Case Study of Korea

    ERIC Educational Resources Information Center

    Lee, Kye Woo

    2006-01-01

    In many developing countries, small- and medium-scale enterprises (SMEs) account for a large part of national employment and income. Therefore, governments have used various strategies/policy instruments to develop human resources for SMEs and improve their productivity and national welfare. In the literature, however, there has been little effort…

  2. Governing the Potentials of Life Itself? Interrogating the Promises in Affective Educational Leadership

    ERIC Educational Resources Information Center

    Staunaes, Dorthe

    2011-01-01

    This article critically explores how educational leadership is becoming increasingly affective in order to cultivate pupil potential and thereby meet the challenge of creating the best schools in the world. It critically analyses policy and handbook approaches to affective educational leadership technologies by showing the difficulty in keeping…

  3. Factors Affecting the Management of Women Groups' Micro and Small Enterprises in Kakamega District, Kenya

    ERIC Educational Resources Information Center

    Wawire, Nelson H. W.; Nafukho, Fredrick M.

    2010-01-01

    Purpose: The purpose of this study is to highlight the main factors that affect the management of the WGs' Micro and Small Enterprises (MSEs) in Kakamega District and Africa in general. Design/methodology/approach: The study adopted a descriptive research design. This is because the study was concerned about a univariate question in which the…

  4. Factors Affecting Electronic Medical Record System Adoption in Small Korean Hospitals

    PubMed Central

    Park, Young-Taek

    2014-01-01

    Objectives The objective of this paper is to investigate the factors affecting adoption of an Electronic Medical Record (EMR) system in small Korean hospitals. Methods This study used survey data on adoption of EMR systems; data included that from various hospital organizational structures. The survey was conducted from April 10 to August 3, 2009. The response rate was 33.5% and the total number of small general hospitals was 144. Data were analyzed using the generalized estimating equation method to adjust for environmental clustering effects. Results The adoption rate of EMR systems was 40.2% for all responding small hospitals. The study results indicate that IT infrastructure (OR, 1.48; 95% CI, 1.23 to 1.80) and organic hospital structure (OR, 1.86; 95% CI, 1.07 to 3.23) rather than mechanistic hospital structure or the number of hospitals within a county (OR, 1.08; 95% CI, 1.01 to 1.17) were critical factors for EMR adoption after controlling for various hospital covariates. Conclusions This study found that several managerial features of hospitals and one environmental factor were related to the adoption of EMR systems in small Korean hospitals. Considering that health information technology produces many positive health outcomes and that an 'adoption gap' regarding information technology exists in small clinical settings, healthcare policy makers should understand which organizational and environmental factors affect adoption of EMR systems and take action to financially support small hospitals during this transition. PMID:25152831

  5. Small but powerful: top predator local extinction affects ecosystem structure and function in an intermittent stream.

    PubMed

    Rodríguez-Lozano, Pablo; Verkaik, Iraima; Rieradevall, Maria; Prat, Narcís

    2015-01-01

    Top predator loss is a major global problem, with a current trend in biodiversity loss towards high trophic levels that modifies most ecosystems worldwide. Most research in this area is focused on large-bodied predators, despite the high extinction risk of small-bodied freshwater fish that often act as apex consumers. Consequently, it remains unknown if intermittent streams are affected by the consequences of top-predators' extirpations. The aim of our research was to determine how this global problem affects intermittent streams and, in particular, if the loss of a small-bodied top predator (1) leads to a 'mesopredator release', affects primary consumers and changes whole community structures, and (2) triggers a cascade effect modifying the ecosystem function. To address these questions, we studied the top-down effects of a small endangered fish species, Barbus meridionalis (the Mediterranean barbel), conducting an enclosure/exclosure mesocosm experiment in an intermittent stream where B. meridionalis became locally extinct following a wildfire. We found that top predator absence led to 'mesopredator release', and also to 'prey release' despite intraguild predation, which contrasts with traditional food web theory. In addition, B. meridionalis extirpation changed whole macroinvertebrate community composition and increased total macroinvertebrate density. Regarding ecosystem function, periphyton primary production decreased in apex consumer absence. In this study, the apex consumer was functionally irreplaceable; its local extinction led to the loss of an important functional role that resulted in major changes to the ecosystem's structure and function. This study evidences that intermittent streams can be affected by the consequences of apex consumers' extinctions, and that the loss of small-bodied top predators can lead to large ecosystem changes. We recommend the reintroduction of small-bodied apex consumers to systems where they have been extirpated, to restore

  6. Small but powerful: top predator local extinction affects ecosystem structure and function in an intermittent stream.

    PubMed

    Rodríguez-Lozano, Pablo; Verkaik, Iraima; Rieradevall, Maria; Prat, Narcís

    2015-01-01

    Top predator loss is a major global problem, with a current trend in biodiversity loss towards high trophic levels that modifies most ecosystems worldwide. Most research in this area is focused on large-bodied predators, despite the high extinction risk of small-bodied freshwater fish that often act as apex consumers. Consequently, it remains unknown if intermittent streams are affected by the consequences of top-predators' extirpations. The aim of our research was to determine how this global problem affects intermittent streams and, in particular, if the loss of a small-bodied top predator (1) leads to a 'mesopredator release', affects primary consumers and changes whole community structures, and (2) triggers a cascade effect modifying the ecosystem function. To address these questions, we studied the top-down effects of a small endangered fish species, Barbus meridionalis (the Mediterranean barbel), conducting an enclosure/exclosure mesocosm experiment in an intermittent stream where B. meridionalis became locally extinct following a wildfire. We found that top predator absence led to 'mesopredator release', and also to 'prey release' despite intraguild predation, which contrasts with traditional food web theory. In addition, B. meridionalis extirpation changed whole macroinvertebrate community composition and increased total macroinvertebrate density. Regarding ecosystem function, periphyton primary production decreased in apex consumer absence. In this study, the apex consumer was functionally irreplaceable; its local extinction led to the loss of an important functional role that resulted in major changes to the ecosystem's structure and function. This study evidences that intermittent streams can be affected by the consequences of apex consumers' extinctions, and that the loss of small-bodied top predators can lead to large ecosystem changes. We recommend the reintroduction of small-bodied apex consumers to systems where they have been extirpated, to restore

  7. Small but Powerful: Top Predator Local Extinction Affects Ecosystem Structure and Function in an Intermittent Stream

    PubMed Central

    Rodríguez-Lozano, Pablo; Verkaik, Iraima; Rieradevall, Maria; Prat, Narcís

    2015-01-01

    Top predator loss is a major global problem, with a current trend in biodiversity loss towards high trophic levels that modifies most ecosystems worldwide. Most research in this area is focused on large-bodied predators, despite the high extinction risk of small-bodied freshwater fish that often act as apex consumers. Consequently, it remains unknown if intermittent streams are affected by the consequences of top-predators’ extirpations. The aim of our research was to determine how this global problem affects intermittent streams and, in particular, if the loss of a small-bodied top predator (1) leads to a ‘mesopredator release’, affects primary consumers and changes whole community structures, and (2) triggers a cascade effect modifying the ecosystem function. To address these questions, we studied the top-down effects of a small endangered fish species, Barbus meridionalis (the Mediterranean barbel), conducting an enclosure/exclosure mesocosm experiment in an intermittent stream where B. meridionalis became locally extinct following a wildfire. We found that top predator absence led to ‘mesopredator release’, and also to ‘prey release’ despite intraguild predation, which contrasts with traditional food web theory. In addition, B. meridionalis extirpation changed whole macroinvertebrate community composition and increased total macroinvertebrate density. Regarding ecosystem function, periphyton primary production decreased in apex consumer absence. In this study, the apex consumer was functionally irreplaceable; its local extinction led to the loss of an important functional role that resulted in major changes to the ecosystem’s structure and function. This study evidences that intermittent streams can be affected by the consequences of apex consumers’ extinctions, and that the loss of small-bodied top predators can lead to large ecosystem changes. We recommend the reintroduction of small-bodied apex consumers to systems where they have been

  8. Factors affecting poor nutritional status after small bowel resection in patients with Crohn disease.

    PubMed

    Jang, Ki Ung; Yu, Chang Sik; Lim, Seok-Byung; Park, In Ja; Yoon, Yong Sik; Kim, Chan Wook; Lee, Jong Lyul; Yang, Suk-Kyun; Ye, Byong Duk; Kim, Jin Cheon

    2016-07-01

    In Crohn disease, bowel-preserving surgery is necessary to prevent short bowel syndrome due to repeated operations. This study aimed to determine the remnant small bowel length cut-off and to evaluate the clinical factors related to nutritional status after small bowel resection in Crohn disease.We included 394 patients (69.3% male) who underwent small bowel resection for Crohn disease between 1991 and 2012. Patients who were classified as underweight (body mass index < 17.5) or at high risk of nutrition-related problems (modified nutritional risk index < 83.5) were regarded as having a poor nutritional status. Preliminary remnant small bowel length cut-offs were determined using receiver operating characteristic curves. Variables associated with poor nutritional status were assessed retrospectively using Student t tests, chi-squared tests, Fisher exact tests, and logistic regression analyses.The mean follow-up period was 52.9 months and the mean patient ages at the time of the last bowel surgery and last follow-up were 31.2 and 35.7 years, respectively. The mean remnant small bowel length was 331.8 cm. Forty-three patients (10.9%) underwent ileostomy, 309 (78.4%) underwent combined small bowel and colon resection, 111 (28.2%) had currently active disease, and 105 (26.6%) underwent at least 2 operations for recurrent disease. The mean body mass index and modified nutritional risk index were 20.6 and 100.8, respectively. The independent factors affecting underweight status were remnant small bowel length ≤240 cm (odds ratio: 4.84, P < 0.001), ileostomy (odds ratio: 4.70, P < 0.001), and currently active disease (odds ratio: 4.16, P < 0.001). The independent factors affecting high nutritional risk were remnant small bowel length ≤230 cm (odds ratio: 2.84, P = 0.012), presence of ileostomy (odds ratio: 3.36, P = 0.025), and currently active disease (odds ratio: 4.90, P < 0.001).Currently active disease, ileostomy, and remnant small

  9. Factors Governing the Effective Remediation of Negative Affect and Its Cognitive and Behavioral Consequences.

    ERIC Educational Resources Information Center

    Barden, R. Christopher; And Others

    A study was conducted in which negative affective states were induced in children by one of several different types of cognition or experience. Subjects were 150 second-grade children, evenly divided by sex, from suburban elementary schools. In particular, cognitive induction procedures involved children's thinking about negative events that might…

  10. Study of Core Competency Elements and Factors Affecting Performance Efficiency of Government Teachers in Northeastern Thailand

    ERIC Educational Resources Information Center

    Chansirisira, Pacharawit

    2012-01-01

    The research aimed to investigate the core competency elements and the factors affecting the performance efficiency of the civil service teachers in the northeastern region, Thailand. The research procedure consisted of two steps. In the first step, the data were collected using a questionnaire with the reliability (Cronbach's Alpha) of 0.90. The…

  11. Photovoltaic commercialization: an analysis of legal issues affecting a government-accelerated solar industry

    SciTech Connect

    Lamm, D.

    1980-06-01

    The Photovoltaics Research, Development, and Demonstration Act of 1978 is discussed. Legal issues, including solar access, the need for performance standards, the effects of building codes on photovoltaic system use and commercialization, and manufacturer and installer performance guarantees, are examined. Electric utility policies are examined, including interconnection, and rates and legal issues affecting them. (LEW)

  12. Small molecule screen for compounds that affect vascular development in the zebrafish retina

    PubMed Central

    Kitambi, Satish S.; McCulloch, Kyle J.; Peterson, Randall T.; Malicki, Jarema J.

    2009-01-01

    Blood vessel formation in the vertebrate eye is a precisely regulated process. In the human retina, both an excess and a deficiency of blood vessels may lead to a loss of vision. To gain insight into the molecular basis of vessel formation in the vertebrate retina and to develop pharmacological means of manipulating this process in a living organism, we further characterized the embryonic zebrafish eye vasculature, and performed a small molecule screen for compounds that affect blood vessel morphogenesis. The screening of approximately 2000 compounds revealed four small molecules that at specific concentrations affect retinal vessel morphology but do not produce obvious changes in trunk vessels, or in the neuronal architecture of the retina. Of these, two induce a pronounced widening of vessel diameter without a substantial loss of vessel number, one compound produces a loss of retinal blood vessels accompanied by a mild increase of their diameter, and finally one other generates a severe loss of retinal vessels. This work demonstrates the utility of zebrafish as a screening tool for small molecules that affect eye vasculature and presents several compounds of potential therapeutic importance. PMID:19445054

  13. Realigning government action with public health evidence: the legal and policy environment affecting sex work and HIV in Asia.

    PubMed

    Gruskin, Sofia; Pierce, Gretchen Williams; Ferguson, Laura

    2014-01-01

    The HIV epidemic has shed light on how government regulation of sex work directly affects the health and well-being of sex workers, their families and communities. A review of the public health evidence highlights the need for supportive legal and policy environments, yet criminalisation of sex work remains standard around the world. Emerging evidence, coupled with evolving political ideologies, is increasingly shaping legal environments that promote the rights and health of sex workers but even as new legislation is created, contradictions often exist with standing problematic legislation. As a region, Asia provides a compelling example in that progressive HIV policies often sit side by side with laws that criminalise sex work. Data from the 21 Asian countries reporting under the UN General Assembly Special Session on HIV in 2010 were analysed to provide evidence of how countries' approach to sex-work regulation might affect HIV-related outcomes. Attention to the links between law and HIV-related outcomes can aid governments to meet their international obligations and ensure appropriate legal environments that cultivate the safe and healthy development and expression of sexuality, ensure access to HIV and other related services and promote and protect human rights.

  14. 77 FR 41403 - Meetings of the Local Government Advisory Committee and the Small Communities Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ...). The Subcommittee will discuss sustainable communities, decentralized wastewater treatment, and other.... (EDT). The Committee will discuss air quality issues, water quality issues, environmental justice and... wastewater treatment, and other issues and recommendations regarding environmental issues affecting...

  15. A Corporate Responsibility? The Constitution of Fly-in, Fly-out Mining Companies as Governance Partners in Remote, Mine-Affected Localities

    ERIC Educational Resources Information Center

    Cheshire, Lynda

    2010-01-01

    In some remote parts of Australia, mining companies have positioned themselves as central actors in governing nearby affected communities by espousing notions of "voluntary partnerships for sustainability" between business, government and community. It is argued in this paper that the nature and extent of mining company interventions in nearby…

  16. 76 FR 26948 - Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... Federal Register of March 25, 2011, in FR Doc. 2011-7135, on page 16703, in the second column, correct the...-0006 must be received on or before June 6, 2011. In the Federal Register of March 25, 2011, in FR Doc... ADMINISTRATION 13 CFR Parts 121, 124, 125, 126, and 127 Small Business Jobs Act Tour: Selected Provisions...

  17. 76 FR 16703 - Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    .... See Notice of Grant Opportunities to States: STEP Grant Program, 76 FR 10082 (Feb. 23, 2011). These... ADMINISTRATION 13 CFR Parts 121, 124, 125, 126, and 127 Small Business Jobs Act Tour: Selected Provisions Having... Jobs Act of 2010 (SBJA). On Monday, March 7, 2011, SBA announced a series of public meetings on...

  18. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... restoration of the affected habitat; (v) The anticipated impact of the loss or modification of the habitat on... habitat and on the availability of the species for subsistence uses, paying particular attention to... contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section:...

  19. High-fibre sunflower cake affects small intestinal digestion and health in broiler chickens.

    PubMed

    Kalmendal, R; Elwinger, K; Holm, L; Tauson, R

    2011-02-01

    1. An experiment was conducted to evaluate high-fibre sunflower cake (HF-SFC); a feed ingredient distinguished by large amounts of crude fibre and insoluble non-starch polysaccharides (i-NSP). 2. Broiler chickens (n = 160) were fed on pelleted maize-based diets free from coccidiostats and antibiotic growth promoters between 15 and 31 d of age. Diets included 0, 10, 20 or 30% HF-SFC. Performance and small intestinal health were assessed. 3. In general, HF-SFC inclusion mediated significant linear increases in ileal digestibility of fat and protein and significant linear decreases in ileal digestibility of dry matter, ash and energy. 4. Weight gain increased linearly with HF-SFC inclusion. Feed conversion was negatively affected by 30% HF-SFC but not by 20% HF-SFC. 5. In the jejunal lumen, inclusion of HF-SFC was associated with significant decreases in colony counts of Clostridium spp. 6. HF-SFC inclusion resulted in significant linear reductions of villus height, thickness of muscularis mucosa, and the circular and longitudinal layers of muscularis in the jejunum. Crypt depth and submucosal thickness were not affected. 7. The data indicate that broiler chickens may thrive on feeds with insoluble fibre contents far exceeding those used in practice, and that HF-SFC exerts some positive effects on digestion and small intestinal health. PMID:21337203

  20. Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila.

    PubMed

    Sahr, Tobias; Brüggemann, Holger; Jules, Matthieu; Lomma, Mariella; Albert-Weissenberger, Christiane; Cazalet, Christel; Buchrieser, Carmen

    2009-05-01

    To transit from intra- to extracellular environments, Legionella pneumophila differentiates from a replicative/non-virulent to a transmissive/virulent form using the two-component system LetA/LetS and the global repressor protein CsrA. While investigating how both regulators act co-ordinately we characterized two ncRNAs, RsmY and RsmZ, that link the LetA/LetS and CsrA regulatory networks. We demonstrate that LetA directly regulates their expression and show that RsmY and RsmZ are functional in Escherichia coli and are able to bind CsrA in vitro. Single mutants have no (ΔrsmY) or a little (ΔrsmZ) impact on virulence, but the ΔrsmYZ strain shows a drastic defect in intracellular growth in Acanthamoeba castellanii and THP-1 monocyte-derived macrophages. Analysis of the transcriptional programmes of the ΔletA, ΔletS and ΔrsmYZ strains revealed that the switch to the transmissive phase is partially blocked. One major difference between the ΔletA, ΔletS and ΔrsmYZ strains was that the latter synthesizes flagella. Taken together, LetA activates transcription of RsmY and RsmZ, which sequester CsrA and abolish its post-transcriptional repressive activity. However, the RsmYZ-CsrA pathway appears not to be the main or only regulatory circuit governing flagella synthesis. We suggest that rather RpoS and LetA, by influencing LetE and probably cyclic-di-GMP levels, regulate motility in L. pneumophila.

  1. Citizen Empowerment through e-Democracy: Patterns of E-Government Adoption for Small-Sized Cities in Missouri

    ERIC Educational Resources Information Center

    Massey, Floyd E., III

    2014-01-01

    E-government is one of the buzzwords in discussing modernizing public administration. Numerous researchers have conducted studies related to the implementation of e-government and e-government 2.0 programs. The main goal of e-government programs is to increase government efficiency and offer benefits to citizens. As the requirements of government…

  2. Water color affects the stratification, surface temperature, heat content, and mean epilimnetic irradiance of small lakes

    USGS Publications Warehouse

    Houser, J.N.

    2006-01-01

    The effects of water color on lake stratification, mean epilimnetic irradiance, and lake temperature dynamics were examined in small, north-temperate lakes that differed widely in water color (1.5-19.8 m -1). Among these lakes, colored lakes differed from clear lakes in the following ways: (i) the epilimnia were shallower and colder, and mean epilimnetic irradiance was reduced; (ii) the diel temperature cycles were more pronounced; (iii) whole-lake heat accumulation during stratification was reduced. The depth of the epilimnion ranged from 2.5 m in the clearest lake to 0.75 m in the most colored lake, and 91% of the variation in epilimnetic depth was explained by water color. Summer mean morning epilimnetic temperature was ???2??C cooler in the most colored lake compared with the clearest lake. In clear lakes, the diel temperature range (1.4 ?? 0.7??C) was significantly (p = 0.01) less than that in the most colored lake (2.1 ?? 1.0??C). Change in whole-lake heat content was negatively correlated with water color. Increasing water color decreased light penetration more than thermocline depth, leading to reduced mean epilimnetic irradiance in the colored lakes. Thus, in these small lakes, water color significantly affected temperature, thermocline depth, and light climate. ?? 2006 NRC.

  3. Criticality governed by the stable renormalization fixed point of the Ising model in the hierarchical small-world network.

    PubMed

    Nogawa, Tomoaki; Hasegawa, Takehisa; Nemoto, Koji

    2012-09-01

    We study the Ising model in a hierarchical small-world network by renormalization group analysis and find a phase transition between an ordered phase and a critical phase, which is driven by the coupling strength of the shortcut edges. Unlike ordinary phase transitions, which are related to unstable renormalization fixed points (FPs), the singularity in the ordered phase of the present model is governed by the FP that coincides with the stable FP of the ordered phase. The weak stability of the FP yields peculiar criticalities, including logarithmic behavior. On the other hand, the critical phase is related to a nontrivial FP, which depends on the coupling strength and is continuously connected to the ordered FP at the transition point. We show that this continuity indicates the existence of a finite correlation-length-like quantity inside the critical phase, which diverges upon approaching the transition point.

  4. Is rumen development in newborn calves affected by different liquid feeds and small intestine development?

    PubMed

    Górka, P; Kowalski, Z M; Pietrzak, P; Kotunia, A; Jagusiak, W; Zabielski, R

    2011-06-01

    fed MR. Significant positive Pearson correlations were found between small intestine and reticulorumen weights as well as between activity of brush border lactase, maltase, aminopeptidase A, and aminopeptidase N and reticulorumen weight. Different liquid feeds affect small intestine development, animal growth, solid feed intake and metabolic status of calves and this effect can indirectly influence the development of forestomachs.

  5. Noise-affected I - V curves in small hysteretic Josephson junctions

    SciTech Connect

    Kautz, R.L.; Martinis, J.M. )

    1990-12-01

    We investigate the noise-affected {ital I}-{ital V} curves of small-area Josephson junctions through experiment, simulation, and theory. In particular, we consider {ital I}-{ital V} curves in which two different states of finite voltage coexist at the same dc bias: a high-voltage state that corresponds to the usual quasiparticle branch and a low-voltage state that is characterized by thermally activated phase diffusion. The observed hysteresis between the phase-diffusion and quasiparticle branches cannot be explained within the context of the simple resistively and capacitively shunted junction (RCSJ) model but is explained by extended models in which the damping increases with frequency. Frequency-dependent damping is shown to produce a qualitative change in the attractors of the noise-free system which allows the two voltage states to be simultaneously stable. This picture is confirmed by Monte Carlo simulations which accurately reproduce the experimental {ital I}-{ital V} curves of two different samples over a wide range of temperatures. In addition we develop analytic expressions for three key parameters of the {ital I}-{ital V} curve of junctions displaying hysteresis between the phase-diffusion and quasiparticle branches: the initial slope of the phase-diffusion branch, the bias level at which the junction switches from the phase-diffusion branch to the quasiparticle branch, and the bias level at which it returns to the phase-diffusion branch.

  6. Variables that affect the expansion rate and outcome of small abdominal aortic aneurysms.

    PubMed

    Cronenwett, J L; Sargent, S K; Wall, M H; Hawkes, M L; Freeman, D H; Dain, B J; Curé, J K; Walsh, D B; Zwolak, R M; McDaniel, M D

    1990-02-01

    Seventy-three patients with small (less than 6 cm in diameter) abdominal aortic aneurysms (AAAs) were selected for nonoperative management and followed up with sequential ultrasound size measurements. Fifty-four men and 19 women, 51 to 89 years of age (mean 70 years), had an initial mean AAA size of 4.1 cm (anteroposterior) x 4.3 cm (lateral) diameter, with a calculated elliptic cross-sectional area of 14.3 cm2. After a mean of 37 months of follow-up, AAA area increased at a mean rate of 20% per year (3 cm2 yr; 0.4 to 0.5 cm/yr diameter). Expansion rate was not affected by initial aneurysm size. During follow-up, only 3 patients (4%) required urgent operation (1 died), 26 patients (36%) died of non-AAA causes, and 26 patients (36%) underwent elective AAA repair because of progressive size increase (1 died). Elective operations were performed at the rate of 10% per year, when mean AAA size had increased to 22 cm2 (5.1 cm in diameter). Multiple regression analysis of clinical parameters available at presentation indicated that subsequent elective AAA repair was predicted by younger age at diagnosis and larger initial aneurysm size. As anticipated, patients who underwent surgery had more rapid aneurysm expansion (5.3 cm2/yr) compared with patients who did not undergo surgery (1.6 cm2/yr; p less than 0.05). This difference was caused by more rapid expansion during later follow-up intervals among patients selected for operation and was not predicted by the change in aneurysm size observed during initial ultrasonographic follow-up. Final aneurysm size was predicted by initial size, duration of follow-up, and both systolic and diastolic pressure.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Do governance, equity characteristics, and venture capital nvolvement affect long-term wealth creation in U.S. health care and biotechnology IPOs?

    PubMed

    Williams, David R; Duncan, W Jack; Ginter, Peter M; Shewchuk, Richard M

    2006-01-01

    Agency theory remains the dominant means of examining governance issues and ownership characteristics related to large organizations. Research in these areas within large organizations has increased our understanding, yet little is known about the influence that these mechanisms and characteristics have had on IPO firm performance. This study tests an agency perspective that venture capital involvement, governance and equity characteristics affect health care and biotechnology IPO firm performance. Our results indicate that there is no correlation between these factors and health care and biotechnology IPO wealth creation. For these entrepreneurs, our findings suggest a contingent approach for the use of these mechanisms.

  8. Understanding Process and Affective Factors in Small Group versus Individual Learning with Technology

    ERIC Educational Resources Information Center

    Lou, Yiping

    2004-01-01

    Based on 198 independent findings from 71 studies with experimental or statistical controls, the results of this meta-analysis indicate that, on average, students learning with computers in small groups attempted a greater amount of task (d + = +0.15), used more learning strategies (d + = +0.36), had more positive attitude toward small group…

  9. One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs.

    PubMed

    Lock, Antonia; Forfar, Rachel; Weston, Cathryn; Bowsher, Leo; Upton, Graham J G; Reynolds, Christopher A; Ladds, Graham; Dixon, Ann M

    2014-12-01

    G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors in mammals and facilitate a range of physiological responses triggered by a variety of ligands. GPCRs were thought to function as monomers, however it is now accepted that GPCR homo- and hetero-oligomers also exist and influence receptor properties. The Schizosaccharomyces pombe GPCR Mam2 is a pheromone-sensing receptor involved in mating and has previously been shown to form oligomers in vivo. The first transmembrane domain (TMD) of Mam2 contains a small-XXX-small motif, overrepresented in membrane proteins and well-known for promoting helix-helix interactions. An ortholog of Mam2 in Saccharomyces cerevisiae, Ste2, contains an analogous small-XXX-small motif which has been shown to contribute to receptor homo-oligomerization, localization and function. Here we have used experimental and computational techniques to characterize the role of the small-XXX-small motif in function and assembly of Mam2 for the first time. We find that disruption of the motif via mutagenesis leads to reduction of Mam2 TMD1 homo-oligomerization and pheromone-responsive cellular signaling of the full-length protein. It also impairs correct targeting to the plasma membrane. Mutation of the analogous motif in Ste2 yielded similar results, suggesting a conserved mechanism for assembly. Using co-expression of the two fungal receptors in conjunction with computational models, we demonstrate a functional change in G protein specificity and propose that this is brought about through hetero-dimeric interactions of Mam2 with Ste2 via the complementary small-XXX-small motifs. This highlights the potential of these motifs to affect a range of properties that can be investigated in other GPCRs.

  10. Variation at Local Government Level in the Support for Families of Severely Disabled Children and the Factors that Affect It

    ERIC Educational Resources Information Center

    Forsyth, Rob; McNally, Richard; James, Peter; Crossland, Kevin; Woolley, Mark; Colver, Allan

    2010-01-01

    Aim: The aim of this study was to examine geographical variability in the support for families caring for children with severe disabilities as well as the relationships between this variability and local government social and educational performance indicators. Method: Data were collected from a cross-sectional, self-completed postal survey of the…

  11. Thinking Big or Small: Does Mental Abstraction Affect Social Network Organization?

    PubMed Central

    Bacev-Giles, Chantal; Peetz, Johanna

    2016-01-01

    Four studies examined how mental abstraction affects how people perceive their relationships with other people, specifically, how these relationships may be categorized in social groups. We expected that individuals induced to think abstractly would report fewer more global social groups, compared to those induced to think concretely, who would report more specific groups. However, induced abstract mindset did not affect how people structured their social groups (Study 2–4), despite evidence that the mindset manipulation changed the level of abstraction in their thoughts (Study 3) and evidence that it changed how people structured groups for a control condition (household objects, Study 4). Together, these studies suggest that while the way people organize their relationships into groups is malleable; cognitive abstraction does not seem to affect how people categorize their relationships into social groups. PMID:26808086

  12. Water Reform and the Resilience of Small Business People in Drought-Affected Agricultural Communities

    ERIC Educational Resources Information Center

    Schwarz, Imogen; Williams, Pam McRae

    2009-01-01

    The impact of drought on rural communities in Australia has been the subject of considerable research. Less well understood are the impacts of drought on rural small businesses and the mechanisms they use to adapt or cope through extended dry periods. In this study, strategies these businesses draw upon to manage this adversity are identified and…

  13. Ratio dependence in small number discrimination is affected by the experimental procedure

    PubMed Central

    Agrillo, Christian; Piffer, Laura; Bisazza, Angelo; Butterworth, Brian

    2015-01-01

    Adults, infants and some non-human animals share an approximate number system (ANS) to estimate numerical quantities, and are supposed to share a second, ‘object-tracking,’ system (OTS) that supports the precise representation of a small number of items (up to 3 or 4). In relative numerosity judgments, accuracy depends on the ratio of the two numerosities (Weber’s Law) for numerosities >4 (the typical ANS range), while for numerosities ≤4 (OTS range) there is usually no ratio effect. However, recent studies have found evidence for ratio effects for small numerosities, challenging the idea that the OTS might be involved for small number discrimination. Here we tested the hypothesis that the lack of ratio effect in the numbers 1–4 is largely dependent on the type of stimulus presentation. We investigated relative numerosity judgments in college students using three different procedures: a simultaneous presentation of intermingled and separate groups of dots in separate experiments, and a further experiment with sequential presentation. As predicted, in the large number range, ratio dependence was observed in all tasks. By contrast, in the small number range, ratio insensitivity was found in one task (sequential presentation). In a fourth experiment, we showed that the presence of intermingled distractors elicited a ratio effect, while easily distinguishable distractors did not. As the different ratio sensitivity for small and large numbers has been often interpreted in terms of the activation of the OTS and ANS, our results suggest that numbers 1–4 may be represented by both numerical systems and that the experimental context, such as the presence/absence of task-irrelevant items in the visual field, would determine which system is activated. PMID:26579032

  14. Factors affecting exercise intensity in rugby-specific small-sided games.

    PubMed

    Kennett, David C; Kempton, Tom; Coutts, Aaron J

    2012-08-01

    Small-sided games (SSGs) have been suggested as a method for concurrently training physical, technical and tactical capabilities of rugby union players. Therefore, it is important to understand how prescriptive variables such as player number and field size influence the training stimulus during rugby-specific SSGs. Twenty semiprofessional rugby union players participated in a series of SSGs of varying player numbers (4 vs. 4, 6 vs. 6, and 8 vs. 8) on small- (32 × 24 m) and large-sized fields (64 × 48 m). The physiological (blood lactate concentration and heart rate [HR]), perceptual (rating of perceived exertion [RPE]), and time-motion demands were assessed for each different SSG format. There were significant differences between the 4 vs. 4, 6 vs. 6, and 8 vs.8 SSG formats in mean speed (meters per minute), high-speed running (HSR) distance (meters), and RPE (all p < 0.05). Blood lactate was greater in 4 vs. 4 compared with that in 8 vs. 8 SSGs. The mean speed, HSR distance, number of sprints, peak speed, blood lactate concentration, and RPE were all significantly different between large- and small-field size (all p < 0.05). There were no significant difference between game formats (4 vs. 4, 6 vs. 6, and 8 vs. 8) or field size (small or large) for either percent HRmax or time spent >85% HRmax. These results show that SSGs with fewer players and larger field sizes elicit greater physiological and perceptual responses and time-motion demands. In contrast, the HR response was similar between all SSG formats, which may be attributable to high levels of individual variability in the HR response. This study provides new information about the influence of player number and field size on the training stimulus provided by rugby-specific SSGs. PMID:21997445

  15. Assessment of the sources of error affecting the quantitative accuracy of SPECT imaging in small animals

    SciTech Connect

    Joint Graduate Group in Bioengineering, University of California, San Francisco and University of California, Berkeley; Department of Radiology, University of California; Gullberg, Grant T; Hwang, Andrew B.; Franc, Benjamin L.; Gullberg, Grant T.; Hasegawa, Bruce H.

    2008-02-15

    Small animal SPECT imaging systems have multiple potential applications in biomedical research. Whereas SPECT data are commonly interpreted qualitatively in a clinical setting, the ability to accurately quantify measurements will increase the utility of the SPECT data for laboratory measurements involving small animals. In this work, we assess the effect of photon attenuation, scatter and partial volume errors on the quantitative accuracy of small animal SPECT measurements, first with Monte Carlo simulation and then confirmed with experimental measurements. The simulations modeled the imaging geometry of a commercially available small animal SPECT system. We simulated the imaging of a radioactive source within a cylinder of water, and reconstructed the projection data using iterative reconstruction algorithms. The size of the source and the size of the surrounding cylinder were varied to evaluate the effects of photon attenuation and scatter on quantitative accuracy. We found that photon attenuation can reduce the measured concentration of radioactivity in a volume of interest in the center of a rat-sized cylinder of water by up to 50percent when imaging with iodine-125, and up to 25percent when imaging with technetium-99m. When imaging with iodine-125, the scatter-to-primary ratio can reach up to approximately 30percent, and can cause overestimation of the radioactivity concentration when reconstructing data with attenuation correction. We varied the size of the source to evaluate partial volume errors, which we found to be a strong function of the size of the volume of interest and the spatial resolution. These errors can result in large (>50percent) changes in the measured amount of radioactivity. The simulation results were compared with and found to agree with experimental measurements. The inclusion of attenuation correction in the reconstruction algorithm improved quantitative accuracy. We also found that an improvement of the spatial resolution through the

  16. Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function 1

    PubMed Central

    Gleeson, M. H.; Bloom, S. R.; Polak, J. M.; Henry, K.; Dowling, R. H.

    1971-01-01

    A 44-year-old woman is described with an endocrine tumour arising in the kidney. There were associated abnormalities of small intestinal morphology, motility, and absorptive function. These abnormalities reversed on removal of the tumour. Detailed studies showed that the tumour contained, and was secreting, glucagon. It is postulated that the intestinal abnormalities may have resulted from glucagon itself or another, as yet unidentified, hormone. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 5Fig. 6 PMID:4941684

  17. Land Use Affects Carbon Sources to the Pelagic Food Web in a Small Boreal Lake

    PubMed Central

    Rinta, Päivi; van Hardenbroek, Maarten; Jones, Roger I.; Kankaala, Paula; Rey, Fabian; Szidat, Sönke; Wooller, Matthew J.; Heiri, Oliver

    2016-01-01

    Small humic forest lakes often have high contributions of methane-derived carbon in their food webs but little is known about the temporal stability of this carbon pathway and how it responds to environmental changes on longer time scales. We reconstructed past variations in the contribution of methanogenic carbon in the pelagic food web of a small boreal lake in Finland by analyzing the stable carbon isotopic composition (δ13C values) of chitinous fossils of planktivorous invertebrates in sediments from the lake. The δ13C values of zooplankton remains show several marked shifts (approx. 10 ‰), consistent with changes in the proportional contribution of carbon from methane-oxidizing bacteria in zooplankton diets. The results indicate that the lake only recently (1950s) obtained its present state with a high contribution of methanogenic carbon to the pelagic food web. A comparison with historical and palaeobotanical evidence indicates that this most recent shift coincided with agricultural land-use changes and forestation of the lake catchment and implies that earlier shifts may also have been related to changes in forest and land use. Our study demonstrates the sensitivity of the carbon cycle in small forest lakes to external forcing and that the effects of past changes in local land use on lacustrine carbon cycling have to be taken into account when defining environmental and ecological reference conditions in boreal headwater lakes. PMID:27487044

  18. Land Use Affects Carbon Sources to the Pelagic Food Web in a Small Boreal Lake.

    PubMed

    Rinta, Päivi; van Hardenbroek, Maarten; Jones, Roger I; Kankaala, Paula; Rey, Fabian; Szidat, Sönke; Wooller, Matthew J; Heiri, Oliver

    2016-01-01

    Small humic forest lakes often have high contributions of methane-derived carbon in their food webs but little is known about the temporal stability of this carbon pathway and how it responds to environmental changes on longer time scales. We reconstructed past variations in the contribution of methanogenic carbon in the pelagic food web of a small boreal lake in Finland by analyzing the stable carbon isotopic composition (δ13C values) of chitinous fossils of planktivorous invertebrates in sediments from the lake. The δ13C values of zooplankton remains show several marked shifts (approx. 10 ‰), consistent with changes in the proportional contribution of carbon from methane-oxidizing bacteria in zooplankton diets. The results indicate that the lake only recently (1950s) obtained its present state with a high contribution of methanogenic carbon to the pelagic food web. A comparison with historical and palaeobotanical evidence indicates that this most recent shift coincided with agricultural land-use changes and forestation of the lake catchment and implies that earlier shifts may also have been related to changes in forest and land use. Our study demonstrates the sensitivity of the carbon cycle in small forest lakes to external forcing and that the effects of past changes in local land use on lacustrine carbon cycling have to be taken into account when defining environmental and ecological reference conditions in boreal headwater lakes. PMID:27487044

  19. The corporate determinants of health: how big business affects our health, and the need for government action!

    PubMed

    Millar, John S

    2013-05-14

    Corporations have a great effect on the health of Canadians.Good companies create jobs, sell valued products at market value, pay a living wage, empower employees, have progressive human resource policies (parental, mental health leaves, workplace wellness programs, day care), and pay their appropriate corporate taxes. They embrace corporate social responsibility and some have a triple bottom line - people, planet and profits. More good corporations are needed.But others are selling products that are damaging to health and the environment, at prices that do not account for these damaging effects and often target consumers that are ill-informed and susceptible (e.g., children). These include businesses involving tobacco, alcohol, drugs, junk foods and beverages, resource extraction, arms production and the electronic media.Governments have a responsibility to take action when the market mechanism fails in this way.A priority for action is the food and beverage sector. The overconsumption of sugar, fat and salt is causing a rising prevalence of all the major chronic diseases, rising health care costs and declining population health and productivity. Urgent government action is required: taxation, advertising and sales restrictions, and a salt reduction program.

  20. The corporate determinants of health: how big business affects our health, and the need for government action!

    PubMed

    Millar, John S

    2013-01-01

    Corporations have a great effect on the health of Canadians.Good companies create jobs, sell valued products at market value, pay a living wage, empower employees, have progressive human resource policies (parental, mental health leaves, workplace wellness programs, day care), and pay their appropriate corporate taxes. They embrace corporate social responsibility and some have a triple bottom line - people, planet and profits. More good corporations are needed.But others are selling products that are damaging to health and the environment, at prices that do not account for these damaging effects and often target consumers that are ill-informed and susceptible (e.g., children). These include businesses involving tobacco, alcohol, drugs, junk foods and beverages, resource extraction, arms production and the electronic media.Governments have a responsibility to take action when the market mechanism fails in this way.A priority for action is the food and beverage sector. The overconsumption of sugar, fat and salt is causing a rising prevalence of all the major chronic diseases, rising health care costs and declining population health and productivity. Urgent government action is required: taxation, advertising and sales restrictions, and a salt reduction program. PMID:24044474

  1. Nitrogen depletion and small R3-MYB transcription factors affecting anthocyanin accumulation in Arabidopsis leaves.

    PubMed

    Nemie-Feyissa, Dugassa; Olafsdottir, Solveig Margret; Heidari, Behzad; Lillo, Cathrine

    2014-02-01

    Ternary complexes consisting of a R2R3-MYB, a bHLH and a WD40 protein (MBW complexes) regulate trichome formation and anthocyanin synthesis in plants. Small R3-MYBs interact with the MBW complexes to exert a negative feedback, and thereby participate in regulation of epidermal cell fate, for example trichome numbers and clustering in leaves. In Arabidopsis thaliana, GL3, a bHLH transcription factor, is important in the MBW complex regulating trichome formation as well as in the MBW complex induced by nitrogen depletion and promoting anthocyanin formation. The small R3-MYBs: CPC, TRY, ETC1, ETC2, ETC3/CPL3, TCL1, MYBL2, are all known to interact with GL3. We here investigated these R3-MYBs in leaves of Arabidopsis rosette stage plants under nitrogen depletion to examine if the small MYBs would interfere with anthocyanin accumulation in plants under normal (autotrophic) growth conditions. CPC expression was enhanced two-fold in response to nitrogen depletion, and ETC3/CPL3 expression was enhanced by almost an order of magnitude (9×). Knockout of ETC3/CPL3 did not influence anthocyanin accumulation, but the results establish ETC3/CPL3 as a nitrate regulated gene and a putative candidate for being involved in nitrate status signaling and root development. Other R3-MYBs tested were not significantly influenced by nitrogen depletion. In conclusion, only CPC expression increased and clearly exerted a negative feedback on anthocyanin accumulation during nitrogen starvation in rosette leaves. PMID:24388610

  2. Small RNA cloning and sequencing strategy affects host and viral microRNA expression signatures.

    PubMed

    Stik, Grégoire; Muylkens, Benoît; Coupeau, Damien; Laurent, Sylvie; Dambrine, Ginette; Messmer, Mélanie; Chane-Woon-Ming, Béatrice; Pfeffer, Sébastien; Rasschaert, Denis

    2014-07-10

    The establishment of the microRNA (miRNA) expression signatures is the basic element to investigate the role played by these regulatory molecules in the biology of an organism. Marek's disease virus 1 (MDV-1) is an avian herpesvirus that naturally infects chicken and induces T cells lymphomas. During latency, MDV-1, like other herpesviruses, expresses a limited subset of transcripts. These include three miRNA clusters. Several studies identified the expression of virus and host encoded miRNAs from MDV-1 infected cell cultures and chickens. But a high discrepancy was observed when miRNA cloning frequencies obtained from different cloning and sequencing protocols were compared. Thus, we analyzed the effect of small RNA library preparation and sequencing on the miRNA frequencies obtained from the same RNA samples collected during MDV-1 infection of chicken at different steps of the oncoviral pathogenesis. Qualitative and quantitative variations were found in the data, depending on the strategy used. One of the mature miRNA derived from the latency-associated-transcript (LAT), mdv1-miR-M7-5p, showed the highest variation. Its cloning frequency was 50% of the viral miRNA counts when a small scale sequencing approach was used. Its frequency was 100 times less abundant when determined through the deep sequencing approach. Northern blot analysis showed a better correlation with the miRNA frequencies found by the small scale sequencing approach. By analyzing the cellular miRNA repertoire, we also found a gap between the two sequencing approaches. Collectively, our study indicates that next-generation sequencing data considered alone are limited for assessing the absolute copy number of transcripts. Thus, the quantification of small RNA should be addressed by compiling data obtained by using different techniques such as microarrays, qRT-PCR and NB analysis in support of high throughput sequencing data. These observations should be considered when miRNA variations are studied

  3. Factors Affecting Student Success in Distance Learning Courses at a Local California Community College: Joint Governance Perspectives

    ERIC Educational Resources Information Center

    Gonzalez, Luis A.

    2012-01-01

    The purpose of this study was to explore the perspectives of staff and faculty regarding factors affecting student success in distance learning at a California community college (CCC). Participants were members of the leadership group known as the distance learning committee. Data were collected through in-depth interviews using open-ended…

  4. Burial Depth and Stolon Internode Length Independently Affect Survival of Small Clonal Fragments

    PubMed Central

    Dong, Bi-Cheng; Liu, Rui-Hua; Zhang, Qian; Li, Hong-Li; Zhang, Ming-Xiang; Lei, Guang-Chun; Yu, Fei-Hai

    2011-01-01

    Disturbance can fragment plant clones into different sizes and unstabilize soils to different degrees, so that clonal fragments of different sizes can be buried in soils at different depths. As a short-term storage organ, solon internode may help fragmented clones of stoloniferous plants to withstand deeper burial in soils. We address (1) whether burial in soils decreases survival and growth of small clonal fragments, and (2) whether increasing internode length increases survival and growth of small fragments under burial. We conducted an experiment with the stoloniferous, invasive herb Alternanthera philoxeroides, in which single-node fragments with stolon internode of 0, 2, 4 and 8 cm were buried in soils at 0, 2, 4 and 8 cm depth, respectively. Increasing burial depth significantly reduced survival of the A. philoxeroides plants and increased root to shoot ratio and total stolon length, but did not change growth measures. Increasing internode length significantly increased survival and growth measures, but there was no interaction effect with burial depth on any traits measured. These results indicate that reserves stored in stolon internodes can contribute to the fitness of the A. philoxeroides plants subject to disturbance. Although burial reduced the regeneration capacity of the A. philoxeroides plants, the species may maintain the fitness by changing biomass allocation and stolon length once it survived the burial. Such responses may play an important role for A. philoxeroides in establishment and invasiveness in frequently disturbed habitats. PMID:21912652

  5. Endocarp thickness affects seed removal speed by small rodents in a warm-temperate broad-leafed deciduous forest, China

    NASA Astrophysics Data System (ADS)

    Zhang, Hongmao; Zhang, Zhibin

    2008-11-01

    Seed traits are important factors affecting seed predation by rodents and thereby the success of recruitment. Seeds of many tree species have hard hulls. These are thought to confer mechanical protection, but the effect of endocarp thickness on seed predation by rodents has not been well investigated. Wild apricot ( Prunus armeniaca), wild peach ( Amygdalus davidiana), cultivated walnut ( Juglans regia), wild walnut ( Juglans mandshurica Maxim) and Liaodong oak ( Quercus liaotungensis) are very common tree species in northwestern Beijing city, China. Their seeds vary greatly in size, endocarp thickness, caloric value and tannin content. This paper aims to study the effects of seed traits on seed removal speed of these five tree species by small rodents in a temperate deciduous forest, with emphasis on the effect of endocarp thickness. The results indicated that speed of removal of seeds released at stations in the field decreased significantly with increasing endocarp thickness. We found no significant correlations between seed removal speed and other seed traits such as seed size, caloric value and tannin content. In seed selection experiments in small cages, Père David's rock squirrel ( Sciurotamias davidianus), a large-bodied, strong-jawed rodent, selected all of the five seed species, and the selection order among the five seed species was determined by endocarp thickness and the ratio of endocarp mass/seed mass. In contrast, the Korean field mouse ( Apodemus peninsulae) and Chinese white-bellied rat ( Niviventer confucianus), with relatively small bodies and weak jaws, preferred to select small seeds like acorns of Q. liaotungensis and seeds of P. armeniaca, indicating that rodent body size is also an important factor affecting food selection based on seed size. These results suggest endocarp thickness significantly reduces seed removal speed by rodents and then negatively affects dispersal fitness of seeds before seed removal of tree species in the study

  6. Grazing by a small fish affects the early stages of a post-settlement stony coral

    NASA Astrophysics Data System (ADS)

    Christiansen, N. A.; Ward, S.; Harii, S.; Tibbetts, I. R.

    2009-03-01

    Short-term experiments were used to isolate the detrimental effects of grazer disturbance on young corals, and determine the stage of development at which recruits are no longer susceptible to this disturbance. Artificial substrata containing an algal matrix and coral recruits of different life stages were exposed to grazing by epilithic algal matrix (EAM) feeding combtoothed blennies, Salarias fasciatus. Single polyp recruits were vulnerable to grazer disturbance, while multi-polyp recruits ( ca. 6-8 polyps) survived with evidence of minor damage in the form of tissue and polyp loss. The result indicates that blennies, although small and possessing weak dentition, can negatively influence the survival of young coral recruits. The protruding structure of micro-nubbins, representing juvenile corals were not damaged, suggesting that coral achieving that size and form can escape such damage.

  7. Role of University-Industry-Government Linkages in the Innovation Processes of a Small Catching-Up Economy

    ERIC Educational Resources Information Center

    Varblane, Urmas; Mets, Tonis; Ukrainski, Kadri

    2008-01-01

    During the transformation process from a command economy, the extraordinary statist university-industry-government (UIG) linkages model was replaced by an extreme version of laissez-faire relationships. A more modern interaction-based UIG model could be implemented only by changing the whole national innovation system of catching-up economies. The…

  8. Factors affecting pupation success of the small hive beetle, Aethina tumida.

    PubMed

    Meikle, W G; Diaz, R

    2012-01-01

    Survivorship of larvae of the small hive beetle, Aethina tumida Murray (Coleoptera: Nitidulidae), was measured after they were raised on one of six diets. The effects of container shape (wide and shallow vs. narrow and deep), soil depth (0, 0.5, 1.0, 2.0, 4.0, and 8.0 cm), and temperature (28°, 32°, or 35° C) on pupation success was measured. Diet influenced larval survivorship, but did not have a strong effect on larval weight. The larvae fed only bee brood survived the shortest period of time. The larvae that were denied pupation substrate, fed only honey and pollen, and no other food or water after 20 days, had a median survivorship of 47.6 days, with a maximum of 61 days, while those fed only brood had a median survivorship of 18.2 days. Pupation substrate was essential for successful pupation, and the depth of the substrate, not its top surface area, was the crucial factor. Pupation success in narrow and deep containers was 95.6% on average, but only 12.5% in wide and shallow containers, using the same soil volume. In narrow and deep containers, most or all larvae kept in 4-8 cm of soil pupated at all temperatures, few larvae kept at 2 cm soil depth pupated, one out of 240 kept at 1.0 cm pupated, and no larvae kept at soil depths of 0 or 0.5 cm pupated.

  9. Factors Affecting Pupation Success of the Small Hive Beetle, Aethina tumida

    PubMed Central

    Meikle, W.G.; Diaz, R.

    2012-01-01

    Survivorship of larvae of the small hive beetle, Aethina tumida Murray (Coleoptera: Nitidulidae), was measured after they were raised on one of six diets. The effects of container shape (wide and shallow vs. narrow and deep), soil depth (0, 0.5, 1.0, 2.0, 4.0, and 8.0 cm), and temperature (28°, 32°, or 35° C) on pupation success was measured. Diet influenced larval survivorship, but did not have a strong effect on larval weight. The larvae fed only bee brood survived the shortest period of time. The larvae that were denied pupation substrate, fed only honey and pollen, and no other food or water after 20 days, had a median survivorship of 47.6 days, with a maximum of 61 days, while those fed only brood had a median survivorship of 18.2 days. Pupation substrate was essential for successful pupation, and the depth of the substrate, not its top surface area, was the crucial factor. Pupation success in narrow and deep containers was 95.6% on average, but only 12.5% in wide and shallow containers, using the same soil volume. In narrow and deep containers, most or all larvae kept in 4–8 cm of soil pupated at all temperatures, few larvae kept at 2 cm soil depth pupated, one out of 240 kept at 1.0 cm pupated, and no larvae kept at soil depths of 0 or 0.5 cm pupated. PMID:23451773

  10. How illumination and contrast affect the area measurement of small particles by digital imaging

    NASA Astrophysics Data System (ADS)

    Taylor, Robert A.; Godbey, Luther C.

    1992-02-01

    Images from conventional video systems are being digitized in computers for the analysis of small particles. The method was developed to automate particle counting and area measurements of dark trash particles in cotton. However, it can be applied to many similar area measurement problems. Because video output is linearly proportional to the amount of light reflected, the best spectral band for optimum particle discrimination should be centered at the wavelength of maximum difference in reflectance between particles and their surroundings. However, due to the distribution of the illumination energy and the distribution of the detector sensitivity, peak performance bands are shifted. Reflectance from cleaned cotton samples and trash particles were measured to define spectral contrast. Pixel intensity histograms form the video system are reported for simulated area reference samples (painted dots on panels) and for actual cotton samples to demonstrate the particle discrimination mechanism. particles from different parts of the cotton plant were used to demonstrate the importance of considering a particle's contrast in the area measurement.

  11. A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.

    PubMed

    McClelland, Erin E; Ramagopal, Udupi A; Rivera, Johanna; Cox, James; Nakouzi, Antonio; Prabu, Moses M; Almo, Steven C; Casadevall, Arturo

    2016-09-01

    The pathogenic yeast Cryptococcus neoformans causes cryptococcosis, a life-threatening fungal disease. C. neoformans has multiple virulence mechanisms that are non-host specific, induce damage and interfere with immune clearance. Microarray analysis of C. neoformans strains serially passaged in mice associated a small gene (CNAG_02591) with virulence. This gene, hereafter identified as HVA1 (hypervirulence-associated protein 1), encodes a protein that has homologs of unknown function in plant and animal fungi, consistent with a conserved mechanism. Expression of HVA1 was negatively correlated with virulence and was reduced in vitro and in vivo in both mouse- and Galleria-passaged strains of C. neoformans. Phenotypic analysis in hva1Δ and hva1Δ+HVA1 strains revealed no significant differences in established virulence factors. Mice infected intravenously with the hva1Δ strain had higher fungal burden in the spleen and brain, but lower fungal burden in the lungs, and died faster than mice infected with H99W or the hva1Δ+HVA1 strain. Metabolomics analysis demonstrated a general increase in all amino acids measured in the disrupted strain and a block in the TCA cycle at isocitrate dehydrogenase, possibly due to alterations in the nicotinamide cofactor pool. Macrophage fungal burden experiments recapitulated the mouse hypervirulent phenotype of the hva1Δ strain only in the presence of exogenous NADPH. The crystal structure of the Hva1 protein was solved, and a comparison of structurally similar proteins correlated with the metabolomics data and potential interactions with NADPH. We report a new gene that modulates virulence through a mechanism associated with changes in fungal metabolism. PMID:27583447

  12. A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals

    PubMed Central

    Cox, James; Nakouzi, Antonio; Prabu, Moses M.; Almo, Steven C.

    2016-01-01

    The pathogenic yeast Cryptococcus neoformans causes cryptococcosis, a life-threatening fungal disease. C. neoformans has multiple virulence mechanisms that are non-host specific, induce damage and interfere with immune clearance. Microarray analysis of C. neoformans strains serially passaged in mice associated a small gene (CNAG_02591) with virulence. This gene, hereafter identified as HVA1 (hypervirulence-associated protein 1), encodes a protein that has homologs of unknown function in plant and animal fungi, consistent with a conserved mechanism. Expression of HVA1 was negatively correlated with virulence and was reduced in vitro and in vivo in both mouse- and Galleria-passaged strains of C. neoformans. Phenotypic analysis in hva1Δ and hva1Δ+HVA1 strains revealed no significant differences in established virulence factors. Mice infected intravenously with the hva1Δ strain had higher fungal burden in the spleen and brain, but lower fungal burden in the lungs, and died faster than mice infected with H99W or the hva1Δ+HVA1 strain. Metabolomics analysis demonstrated a general increase in all amino acids measured in the disrupted strain and a block in the TCA cycle at isocitrate dehydrogenase, possibly due to alterations in the nicotinamide cofactor pool. Macrophage fungal burden experiments recapitulated the mouse hypervirulent phenotype of the hva1Δ strain only in the presence of exogenous NADPH. The crystal structure of the Hva1 protein was solved, and a comparison of structurally similar proteins correlated with the metabolomics data and potential interactions with NADPH. We report a new gene that modulates virulence through a mechanism associated with changes in fungal metabolism. PMID:27583447

  13. Economic efficiency of environmental legislation as it affects small hydropower development at existing dams in North Carolina

    SciTech Connect

    Meardon, K.R.

    1985-01-01

    Small hydropower development at existing dams is affected by a number of pieces of Federal environmental legislation. Such legislation typically does not differentiate between large and small hydropower projects and their relative environmental impacts. Small hydropower development at existing dams is generally thought to have few or minor adverse impacts. The benefits of the environmental legislation may thus be small relative to its costs. This study assesses the economic efficiency (broadly defined to include nonmarket values) of eight major pieces of Federal environmental legislation: the Clean Water Act, the Coastal Zone Management Act, the Endangered Species Act, the Fish and Wildlife Coordination Act, the National Historic Preservation Act, the National Wildlife Refuge Act, and the Wild and Scenic Rivers Act, and the Wilderness Act. The costs examined are real resource costs and lost power production costs. The benefits examined are avoided adverse impacts and improvement in environmental quality. A data base of 152 existing dams in North Carolina was used from which 48 dams were identified as being developed in the absence of the legislation. The effects of the legislation on these dams were then identified, and the costs and benefits estimated. Under the basecase analysis, none of the legislation was found to be economically efficient.

  14. Storminess and geo-hydrological events affecting small coastal basins in a terraced Mediterranean environment.

    PubMed

    Cevasco, Andrea; Diodato, Nazzareno; Revellino, Paola; Fiorillo, Francesco; Grelle, Gerardo; Guadagno, Francesco M

    2015-11-01

    This study was prompted by the occurrence of an extreme Damaging geo-Hydrological Event (DHE) which occurred on October 25th 2011 and which affected a wide area of the northern Mediterranean region. After analysing the storm by means of the precipitation time series, the study attempts to relate the October 25th 2011 DHE with a series of other DHEs that occurred in the period 1954-2012, assessed via the use of historical data and classified according to severity, with a Storm Erosivity Indicator (Ra). The annual mean of the Ra value (2582 MJ mm ha(-1) h(-1) y(-1)) confirmed that the study area is one of the European regions with the highest rainfall erosivity level. A shift in storminess during 1991-2012 with respect to 1954-1990 was observed. A return period of 1000 years was calculated for the single storm erosivity of October 25th, which contributed to 84% of the total annual storm erosivity of 2011 A quite good agreement was found comparing DHE distribution and severity with Ra anomalies over time. As a matter of fact, most of the low severity DHEs (62.5%) occurred in years in which the Ra was below the average value. Moreover, almost all DHEs (93%) ranging from medium- to very high-severity occurred in years for which the Ra exceeded the average value. With regard to the occurrence of the most severe DHE classes, a threshold of the Ra and a recurrence time of approximately 3300 MJ mm ha(-1) h(-1) y(-1) and 12 years, respectively, were identified. Finally, some evidences suggest that an increasing frequency of DHEs is expected in the forthcoming years. It is argued that understanding these issues is a major priority for future research in order to improve land and urban planning strategies for preserving people and the environment, leading ultimately to an effective risk reduction.

  15. Groundwater contributions to metal transport in a small river affected by mining and smelting waste.

    PubMed

    Coynel, Alexandra; Schäfer, Jörg; Dabrin, Aymeric; Girardot, Naïg; Blanc, Gérard

    2007-08-01

    The Riou Mort watershed, strongly affected by former coal mining and Zn ore treatment, has been the major source of the historical polymetallic pollution of the Lot-Garonne-Gironde fluvial-estuarine system. Two decades after the end of ore treatment, the former industrial area still contributes important amounts of metals/metalloids from various, partly unidentified, sources to the downstream river system. This study presents the high spatial variability of metal/metalloid (Cd, Zn, As, Sb, U, V) concentrations in water and suspended particulate matter (SPM) from eight observation sites during a short, intense flood event. Despite important dilution effects, the observed concentration levels at the different sites suggested additional Cd and Zn inputs, probably from polluted groundwater. This formerly unknown metal source was then localized and characterized by sampling water and SPM along two longitudinal profiles during different hydrological situations. Groundwater inputs of "truly dissolved" (<0.02 microm) Cd and Zn occurred along approximately 200 m, contributing 43% and 28% to the total annual (2004) Cd and Zn fluxes in the Riou Mort River. The estimated groundwater concentrations of Cd and Zn (2500-6700 and 83,000-170,000 microg l(-1), respectively) in the source zone were consistent with values measured in samples from the near aquifer (5400-13,000 and 200,000-400,000 microg l(-1)). The present work induced concrete remediation actions (pumping and treatment of the polluted groundwater), that are expected to strongly reduce dissolved Cd and Zn emissions into the Riou Mort River.

  16. Affective Balance, Team Prosocial Efficacy and Team Trust: A Multilevel Analysis of Prosocial Behavior in Small Groups

    PubMed Central

    Cuadrado, Esther; Tabernero, Carmen

    2015-01-01

    Little research has focused on how individual- and team-level characteristics jointly influence, via interaction, how prosocially individuals behave in teams and few studies have considered the potential influence of team context on prosocial behavior. Using a multilevel perspective, we examined the relationships between individual (affective balance) and group (team prosocial efficacy and team trust) level variables and prosocial behavior towards team members. The participants were 123 students nested in 45 small teams. A series of multilevel random models was estimated using hierarchical linear and nonlinear modeling. Individuals were more likely to behave prosocially towards in-group members when they were feeling good. Furthermore, the relationship between positive affective balance and prosocial behavior was stronger in teams with higher team prosocial efficacy levels as well as in teams with higher team trust levels. Finally, the relevance of team trust had a stronger influence on behavior than team prosocial efficacy. PMID:26317608

  17. Affective Balance, Team Prosocial Efficacy and Team Trust: A Multilevel Analysis of Prosocial Behavior in Small Groups.

    PubMed

    Cuadrado, Esther; Tabernero, Carmen

    2015-01-01

    Little research has focused on how individual- and team-level characteristics jointly influence, via interaction, how prosocially individuals behave in teams and few studies have considered the potential influence of team context on prosocial behavior. Using a multilevel perspective, we examined the relationships between individual (affective balance) and group (team prosocial efficacy and team trust) level variables and prosocial behavior towards team members. The participants were 123 students nested in 45 small teams. A series of multilevel random models was estimated using hierarchical linear and nonlinear modeling. Individuals were more likely to behave prosocially towards in-group members when they were feeling good. Furthermore, the relationship between positive affective balance and prosocial behavior was stronger in teams with higher team prosocial efficacy levels as well as in teams with higher team trust levels. Finally, the relevance of team trust had a stronger influence on behavior than team prosocial efficacy.

  18. Do government brochures affect physical activity cognition? A pilot study of Canada's physical activity guide to healthy active living.

    PubMed

    Kliman, Aviva M; Rhodes, Ryan

    2008-08-01

    Health Canada has published national physical activity (PA) guidelines, which are included in their 26-page Physical Activity Guide to Healthy Active Living (CPAG). To date, the use of CPAG as a motivational instrument for PA promotion has not been evaluated. The purpose of this study was to determine whether reading CPAG 1) increased motivational antecedents to engage in regular PA, and 2) increased regular PA intention and behaviour over 1 month. Participants included 130 randomly sampled Canadian adults (18 years or older) who were randomly mailed pack ages consisting of either 1) a questionnaire and a copy of CPAG, or 2) a questionnaire. Questionnaire items pertained to participants' sociodemographics, previous PA behaviours (Godin Leisure-Time Questionnaire) and PA motivation (theory of planned behaviour). Participants were then sent a follow-up questionnaire pertaining to their PA behaviours throughout the previous month. Results revealed significant interactions between the guide condition and previous activity status on instrumental behavioural beliefs about strength activities and subjective norms about endurance activities (p < 0.05), but all other factors were not significantly different. It was concluded that among previously inactive people, receiving this guide may change some informational/motivational constructs, but key motivational antecedents (affective attitude, perceived behavioural control) and outcomes (intention, behaviour) seem unaffected. PMID:18825580

  19. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes.

    PubMed

    Friedli, Lynne; Stearn, Robert

    2015-06-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employability is now widely promoted. This work and the discourse on it are central to the experience of many claimants and contribute to the view that unemployment is evidence of both personal failure and psychological deficit. The use of psychology in the delivery of workfare functions to erase the experience and effects of social and economic inequalities, to construct a psychological ideal that links unemployment to psychological deficit, and so to authorise the extension of state-and state-contracted-surveillance to psychological characteristics. This paper describes the coercive and punitive nature of many psycho-policy interventions and considers the implications of psycho-policy for the disadvantaged and excluded populations who are its primary targets. We draw on personal testimonies of people experiencing workfare, policy analysis and social media records of campaigns opposed to workfare in order to explore the extent of psycho-compulsion in workfare. This is an area that has received little attention in the academic literature but that raises issues of ethics and professional accountability and challenges the field of medical humanities to reflect more critically on its relationship to psychology.

  20. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes

    PubMed Central

    Friedli, Lynne; Stearn, Robert

    2015-01-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employability is now widely promoted. This work and the discourse on it are central to the experience of many claimants and contribute to the view that unemployment is evidence of both personal failure and psychological deficit. The use of psychology in the delivery of workfare functions to erase the experience and effects of social and economic inequalities, to construct a psychological ideal that links unemployment to psychological deficit, and so to authorise the extension of state—and state-contracted—surveillance to psychological characteristics. This paper describes the coercive and punitive nature of many psycho-policy interventions and considers the implications of psycho-policy for the disadvantaged and excluded populations who are its primary targets. We draw on personal testimonies of people experiencing workfare, policy analysis and social media records of campaigns opposed to workfare in order to explore the extent of psycho-compulsion in workfare. This is an area that has received little attention in the academic literature but that raises issues of ethics and professional accountability and challenges the field of medical humanities to reflect more critically on its relationship to psychology. PMID:26052120

  1. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes.

    PubMed

    Friedli, Lynne; Stearn, Robert

    2015-06-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employability is now widely promoted. This work and the discourse on it are central to the experience of many claimants and contribute to the view that unemployment is evidence of both personal failure and psychological deficit. The use of psychology in the delivery of workfare functions to erase the experience and effects of social and economic inequalities, to construct a psychological ideal that links unemployment to psychological deficit, and so to authorise the extension of state-and state-contracted-surveillance to psychological characteristics. This paper describes the coercive and punitive nature of many psycho-policy interventions and considers the implications of psycho-policy for the disadvantaged and excluded populations who are its primary targets. We draw on personal testimonies of people experiencing workfare, policy analysis and social media records of campaigns opposed to workfare in order to explore the extent of psycho-compulsion in workfare. This is an area that has received little attention in the academic literature but that raises issues of ethics and professional accountability and challenges the field of medical humanities to reflect more critically on its relationship to psychology. PMID:26052120

  2. Life expectancy estimation in small administrative areas with non-uniform population sizes: application to Australian New South Wales local government areas

    PubMed Central

    Stephens, Alexandre S; Purdie, Stuart; Yang, Baohui; Moore, Helen

    2013-01-01

    Objective To determine a practical approach for deriving life expectancy estimates in Australian New South Wales local government areas which display a large diversity in population sizes. Design Population-based study utilising mortality and estimated residential population data. Setting 153 local government areas in New South Wales, Australia. Outcome measures Key performance measures of Chiang II, Silcocks, adjusted Chiang II and Bayesian random effects model methodologies of life expectancy estimation including agreement analysis of life expectancy estimates and comparison of estimate SEs. Results Chiang II and Silcocks methods produced almost identical life expectancy estimates across a large range of population sizes but calculation failures and excessively large SEs limited their use in small populations. A population of 25 000 or greater was required to estimate life expectancy with SE of 1 year or less using adjusted Chiang II (a composite of Chiang II and Silcocks methods). Data aggregation offered some remedy for extending the use of adjusted Chiang II in small populations but reduced estimate currency. A recently developed Bayesian random effects model utilising the correlation in mortality rates between genders, age groups and geographical areas markedly improved the precision of life expectancy estimates in small populations. Conclusions We propose a hybrid approach for the calculation of life expectancy using the Bayesian random effects model in populations of 25 000 or lower permitting the precise derivation of life expectancy in small populations. In populations above 25 000, we propose the use of adjusted Chiang II to guard against violations of spatial correlation, to benefit from a widely accepted method that is simpler to communicate to local health authorities and where its slight inferior performance compared with the Bayesian approach is of minor practical significance. PMID:24302503

  3. Proteomic analyses identify a diverse array of nuclear processes affected by small ubiquitin-like modifier conjugation in Arabidopsis

    PubMed Central

    Miller, Marcus J.; Barrett-Wilt, Gregory A.; Hua, Zhihua; Vierstra, Richard D.

    2010-01-01

    The covalent attachment of SUMO (small ubiquitin-like modifier) to other intracellular proteins affects a broad range of nuclear processes in yeast and animals, including chromatin maintenance, transcription, and transport across the nuclear envelope, as well as protects proteins from ubiquitin addition. Substantial increases in SUMOylated proteins upon various stresses have also implicated this modification in the general stress response. To help understand the role(s) of SUMOylation in plants, we developed a stringent method to isolate SUMO-protein conjugates from Arabidopsis thaliana that exploits a tagged SUMO1 variant that faithfully replaces the wild-type protein. Following purification under denaturing conditions, SUMOylated proteins were identified by tandem mass spectrometry from both nonstressed plants and those exposed to heat and oxidative stress. The list of targets is enriched for factors that direct SUMOylation and for nuclear proteins involved in chromatin remodeling/repair, transcription, RNA metabolism, and protein trafficking. Targets of particular interest include histone H2B, components in the LEUNIG/TOPLESS corepressor complexes, and proteins that control histone acetylation and DNA methylation, which affect genome-wide transcription. SUMO attachment site(s) were identified in a subset of targets, including SUMO1 itself to confirm the assembly of poly-SUMO chains. SUMO1 also becomes conjugated with ubiquitin during heat stress, thus connecting these two posttranslational modifications in plants. Taken together, we propose that SUMOylation represents a rapid and global mechanism for reversibly manipulating plant chromosomal functions, especially during environmental stress. PMID:20813957

  4. 40 CFR Table 1a to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Table 1A to Subpart Ec of Part 60—Emissions Limits for Small, Medium, and Large HMIWI at Affected... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(1) and (2) 1A Table 1A to Subpart Ec...

  5. 40 CFR Table 1b to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Table 1B to Subpart Ec of Part 60—Emissions Limits for Small, Medium, and Large HMIWI at Affected... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(3) and (4) 1B Table 1B to Subpart Ec...

  6. The challenges of supplying water to small, scattered communities in the Lower Okavango Basin (LOB), Ngamiland, Botswana: An evaluation of government policy and performance

    NASA Astrophysics Data System (ADS)

    Swatuk, Larry A.; Kgomotso, Phemo K.

    Supplying adequate water and sanitation facilities to small, scattered rural communities and/or large, fast growing settlements in remote areas is a challenge not easily met anywhere in the world. This article focuses on just such a challenge in the remote, rural area of Ngamiland District in north-western Botswana. Drawing on a combination of critical analysis of government and secondary data, participant observation, and key stakeholder interviews conducted over the period 2004-2006, the article shows that despite a good aggregate record of supplying water and sanitation throughout the country, there are abiding, often serious, problems with supply in remote areas. The research reveals that due to a combination of limited human and financial resource capacity, government policy that deliberately under-serves remote areas in order to encourage resettlement, and complacence among key decision-takers, supply problems go unresolved. The article suggests four key interventions as possible ways forward: using the Okavango Delta Management Plan (ODMP) process as a guiding framework for institutional reform; linking research directly to human resource capacity development; treating water as both a social and an economic good; and soliciting an IWRM ‘champion’ to drive the political process.

  7. Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation.

    PubMed Central

    Mungre, S; Enderle, K; Turk, B; Porrás, A; Wu, Y Q; Mumby, M C; Rundell, K

    1994-01-01

    Three independent point mutations within residues 97 to 103 of the simian virus 40-small-t antigen (small-t) greatly reduced the ability of purified small-t to inhibit protein phosphatase 2A in vitro. These mutations affected the interaction of small-t antigen with the protein phosphatase 2A A subunit translated in vitro, and a peptide from the region identified by these mutations released the A subunit from immune complexes. When introduced into virus, the mutations eliminated the ability of small-t to enhance viral transformation of growth-arrested rat F111 cells. In contrast, the mutant small-t antigens were unimpaired in the transactivation of the adenovirus E2 promoter, an activity which was reduced by a double mutation in small-t residues 43 and 45. Images PMID:8107228

  8. Down-regulation of small rubber particle protein expression affects integrity of rubber particles and rubber content in Taraxacum brevicorniculatum.

    PubMed

    Hillebrand, Andrea; Post, Janina J; Wurbs, David; Wahler, Daniela; Lenders, Malte; Krzyzanek, Vladislav; Prüfer, Dirk; Gronover, Christian Schulze

    2012-01-01

    The biosynthesis of rubber is thought to take place on the surface of rubber particles in laticifers, highly specialized cells that are present in more than 40 plant families. The small rubber particle protein (SRPP) has been supposed to be involved in rubber biosynthesis, and recently five SRPPs (TbSRPP1-5) were identified in the rubber-producing dandelion species Taraxacum brevicorniculatum. Here, we demonstrate by immunogold labeling that TbSRPPs are localized to rubber particles, and that rubber particles mainly consist of TbSRPP3, 4 and 5 as shown by high-resolution two-dimensional gel electrophoresis and mass spectrometric analysis. We also carried out an RNA-interference approach in transgenic plants to address the function of TbSRPPs in rubber biosynthesis as well as rubber particle morphology and stability. TbSRPP-RNAi transgenic T. brevicorniculatum plants showed a 40-50% reduction in the dry rubber content, but neither the rubber weight average molecular mass nor the polydispersity of the rubber were affected. Although no phenotypical differences to wild-type particles could be observed in vivo, rubber particles from the TbSRPP-RNAi transgenic lines were less stable and tend to rapidly aggregate in expelling latex after wounding of laticifers. Our results prove that TbSRPPs are very crucial for rubber production in T. brevicorniculatum, probably by contributing to a most favourable and stable rubber particle architecture for efficient rubber biosynthesis and eventually storage.

  9. Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryo

    PubMed Central

    Onjiko, Rosemary M.; Moody, Sally A.; Nemes, Peter

    2015-01-01

    Spatial and temporal changes in molecular expression are essential to embryonic development, and their characterization is critical to understand mechanisms by which cells acquire different phenotypes. Although technological advances have made it possible to quantify expression of large molecules during embryogenesis, little information is available on metabolites, the ultimate indicator of physiological activity of the cell. Here, we demonstrate that single-cell capillary electrophoresis-electrospray ionization mass spectrometry is able to test whether differential expression of the genome translates to the domain of metabolites between single embryonic cells. Dissection of three different cell types with distinct tissue fates from 16-cell embryos of the South African clawed frog (Xenopus laevis) and microextraction of their metabolomes enabled the identification of 40 metabolites that anchored interconnected central metabolic networks. Relative quantitation revealed that several metabolites were differentially active between the cell types in the wild-type, unperturbed embryos. Altering postfertilization cytoplasmic movements that perturb dorsal development confirmed that these three cells have characteristic small-molecular activity already at cleavage stages as a result of cell type and not differences in pigmentation, yolk content, cell size, or position in the embryo. Changing the metabolite concentration caused changes in cell movements at gastrulation that also altered the tissue fates of these cells, demonstrating that the metabolome affects cell phenotypes in the embryo. PMID:25941375

  10. Long-term sediment yield from small catchment in southern Brazil affected by land use and soil management changes.

    NASA Astrophysics Data System (ADS)

    Gomes Minella, Jean Paolo; Henrique Merten, Gustavo; Alessandra Peixoto de Barros, Claudia; Dalbianco, Leandro; Ramon, Rafael; Schlesner, Alexandre

    2015-04-01

    Soil erosion and sediment yield are the main cause of soil degradation in Brazil. Despite this, there is a lack of information about the effects of the soil management on the hydrology and sediment yield at catchment scale. This study aimed to investigate the long-term relationship between the land use and sediment yield in a small catchment with significant changes in soil management, and its impacts on soil erosion and sediment yield. To account the anthropogenic and climatic effects on sediment yield were monitored precipitation, stream flow and suspended sediment concentration during thirteen years (2002 and 2014) at 10 minutes interval and the changes that occurred each year in the land use and soil management. Despite the influence of climate on the sediment yield, the results clearly show three distinct periods affected by the land use and soil management changes during this this period. In the first four years (2002-2004) the predominant land use was the tobacco with traditional soil management, where the soils are plough every year and without winter cover crop. In this period the sediment yield reached the order of 160 t.ha-1.y-1. In the period of 2005-2009, a soil conservation program introduced the adoption of minimum tillage in the catchment and the sediment yield decrease to 70 t.ha-1.y-1. In the last period (2010-2014) there was a partial return to the traditional soil management practices with an increase trend in sediment yield. However, there was also an increase in reforestation areas with positive effect in reducing erosion and sediment yield. The magnitude order of sediment yield in this period was 100 t.ha-1.y-1. The long term sediment yield data was able to demonstrate the impact of the improved management practices in reducing soil erosion and sediment yield. The results allowed a good understanding of the changing sediment dynamics and soil erosion at catchment scale.

  11. LACC Shared Governance Model.

    ERIC Educational Resources Information Center

    Spangler, Mary

    This document discusses Los Angeles City College's (LACC) (California) Shared Governance Model. In response to California Assembly Bill 1725, LACC set forth a plan to implement the statutory requirements of shared governance. Shared governance is a concept grounded in the idea that decision-making is a process that affects the entire campus…

  12. The role of HIV/AIDS committees in effective workplace governance of HIV/AIDS in South African small and medium-sized enterprises (SMEs).

    PubMed

    Vaas, Jocelyn R

    2008-04-01

    The primary purpose of this study was to assess the role, status and scope of workplace HIV/AIDS committees as a means of effective workplace governance of the HIV/AIDS impact, and their role in extending social protective HIV/AIDS-related rights to employees. In-depth qualitative case studies were conducted in five South African small and medium-sized enterprises (SMEs) that were actively implementing HIV/AIDS policies and programmes. Companies commonly implemented HIV/AIDS policies and programmes through a workplace committee dedicated to HIV/AIDS or a generic committee dealing with issues other than HIV/ AIDS. Management, through the human resources department and the occupational health practitioner often drove initial policy formulation, and had virtually sole control of the HIV/AIDS budget. Employee members of committees were mostly volunteers, and were often production or blue collar employees, while there was a notable lack of participation by white-collar employees, line management and trade unions. While the powers of workplace committees were largely consultative, employee committee members often managed in an indirect manner to secure and extend social protective rights on HIV/AIDS to employees, and monitor their effective implementation in practice. In the interim, workplace committees represented one of the best means to facilitate more effective workplace HIV/AIDS governance. However, the increased demands on collective bargaining as a result of an anticipated rises in AIDS-related morbidity and mortality might prove to be beyond the scope of such voluntary committees in the longer term.

  13. A bill to amend the Small Business Act to ensure small businesses affected by the onset of transmissible diseases are eligible for disaster relief.

    THOMAS, 113th Congress

    Sen. Rubio, Marco [R-FL

    2016-09-08

    09/08/2016 Read twice and referred to the Committee on Small Business and Entrepreneurship. (Sponsor introductory remarks on measure: CR S5471-5473) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  14. The effects of free government health insurance among small children--evidence from the free care for children under six policy in Vietnam.

    PubMed

    Nguyen, Ha; Wang, Wenjuan

    2013-01-01

    Over the last few years, there have been an increasing number of impact evaluations of health insurance and other demand-side financing programs in developing countries. Yet the literature on insurance impact among small children is limited. This paper evaluates the effects of a Vietnamese government's policy in 2005, which granted free access to health services in public facilities to all children younger than 6 years. In particular, we focus on children among households who are not eligible for a program for the poor, which has been administered concurrently in the country. Using two waves of the Vietnam Household Living Standard Surveys conducted right before and after the policy started and a difference-in-differences method, we found a major increase in both inpatient and outpatient care in the secondary public hospitals. At the same time, there is evidence indicating a reduction in the use of tertiary hospitals. Compared with the policy's non-beneficiaries, beneficiaries in the age group 4-5 years also experienced fewer sick days, incurred less out-of-pocket spending on healthcare, and were less likely to encounter catastrophic expenditure. Evidence thus suggests that insurance provided by the policy has served the function as a safety net and helped improving efficiency of the health system by reducing the use of costly tertiary care.

  15. "Governance" or "Governing"?

    ERIC Educational Resources Information Center

    Leslie, David

    This paper draws on four perspectives on power and its exercise in organizations to analyze the practice of governing colleges and universities. The exploration uses political theories (particularly those assessing the legitimacy and effectiveness of stable political entities), leadership studies, analyses of how formal and informal organizations…

  16. State Governance Action Report, 2008

    ERIC Educational Resources Information Center

    Ogle, Greg

    2008-01-01

    This is the fifth edition of the State Governance Action Report that has been produced since 2000 by the Association of Governing Boards of Universities and Colleges' (AGB's) Ingram Center for Public Trusteeship and Governance. Focusing primarily on state and higher education policies directly affecting governance, trusteeship, and institutionally…

  17. State Governance Action Report, 2007

    ERIC Educational Resources Information Center

    Association of Governing Boards of Universities and Colleges, 2007

    2007-01-01

    This paper presents the State Governance Action Report for 2007. Compiled in this report are state policy developments, including legislation, commissions, and studies, affecting the structure, responsibilities, and operations of public higher education governing boards and institutionally related foundations. Governance and governance-related…

  18. Introduced species and abiotic factors affect longitudinal variation in small fish assemblages in the Wind River watershed, Wyoming

    USGS Publications Warehouse

    Lionberger, P.S.; Hubert, W.A.

    2007-01-01

    We assessed longitudinal variation in small fish assemblages in the Wind River watershed upstream from Boysen Reservoir, Wyoming and into the reservoir. Twenty-six species were found in the study area, and 12 of the species were believed to have been introduced since settlement by Europeans. Additions and losses of fish species occurred with downstream progression, especially the addition of introduced species. Introduced species increased from 25% of the total number of species in the upper-most river segment (31.5-35.3 km upstream from the reservoir), to 46% in the river segment immediately upstream from the reservoir, to 48% in the reservoir. The most abundant species in the riverine portion of the watershed was the introduced sand shiner (Notropis stramineus). The results suggest that cyprinid species introduced to the upstream watershed and Boysen Reservoir are influencing small fish assemblages upstream from the reservoir and may be impacting native fishes, particularly native cyprinids.

  19. 40 CFR Table 1b to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(3) and (4) 1B Table 1B to Subpart Ec of...: Hospital/Medical/Infectious Waste Incinerators Pt. 60, Subpt. Ec, Table 1B Table 1B to Subpart Ec of Part...(a)(3) and (4) Pollutant Units(7 percent oxygen, dry basis) Emissions limits HMIWI size Small...

  20. 40 CFR Table 1a to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(1) and (2) 1A Table 1A to Subpart Ec of... Waste Incinerators for Which Construction is Commenced After June 20, 1996 Pt. 60, Subpt. Ec, Table 1A Table 1A to Subpart Ec of Part 60—Emissions Limits for Small, Medium, and Large HMIWI at...

  1. 40 CFR Table 1a to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(1) and (2) 1A Table 1A to Subpart Ec of...: Hospital/Medical/Infectious Waste Incinerators Pt. 60, Subpt. Ec, Table 1A Table 1A to Subpart Ec of Part...(a)(1) and (2) Pollutant Units (7 percent oxygen, dry basis) Emissions limits HMIWI size Small...

  2. 40 CFR Table 1b to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(3) and (4) 1B Table 1B to Subpart Ec of...: Hospital/Medical/Infectious Waste Incinerators Pt. 60, Subpt. Ec, Table 1B Table 1B to Subpart Ec of Part...(a)(3) and (4) Pollutant Units(7 percent oxygen, dry basis) Emissions limits HMIWI size Small...

  3. 40 CFR Table 1b to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(3) and (4) 1B Table 1B to Subpart Ec of... Waste Incinerators for Which Construction is Commenced After June 20, 1996 Pt. 60, Subpt. Ec, Table 1B Table 1B to Subpart Ec of Part 60—Emissions Limits for Small, Medium, and Large HMIWI at...

  4. 40 CFR Table 1a to Subpart Ec of... - Emissions Limits for Small, Medium, and Large HMIWI at Affected Facilities as Defined in § 60.50c...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Large HMIWI at Affected Facilities as Defined in § 60.50c(a)(1) and (2) 1A Table 1A to Subpart Ec of...: Hospital/Medical/Infectious Waste Incinerators Pt. 60, Subpt. Ec, Table 1A Table 1A to Subpart Ec of Part...(a)(1) and (2) Pollutant Units (7 percent oxygen, dry basis) Emissions limits HMIWI size Small...

  5. Dietary amino acid levels and feed restriction affect small intestinal development, mortality, and weight gain of male broilers.

    PubMed

    Wijtten, P J A; Hangoor, E; Sparla, J K W M; Verstegen, M W A

    2010-07-01

    This study investigated the effect of 2 different dietary amino acid treatments and feed restriction in early life versus a control treatment on development of the small intestine segments (weights), mortality, and broiler performance. Each treatment was applied to 6 cages with Ross 308 male broilers and to 6 cages with Cobb 500 male broilers with 24 birds per cage. A control treatment (100% ideal protein) was compared with a treatment with 30% extra ideal protein, a treatment with daily adjustment of the dietary amino acid level and profile, and a feed restriction treatment. The protein treatments were applied from 0 to 14 d of age. The feed restriction was applied from 4 to 21 d of age. Restriction was 15% from d 4 to 14 of age and diminished with equal daily steps thereafter to 5% at 21 d of age. Birds were weighed and dissected for evaluation of small intestine weights at 6, 9, 14, and 36 d of age. Feed intake restriction reduced leg problems in Ross and Cobb broilers. Extra dietary protein reduced leg problems in Ross broilers only. The present experiment does not show that small intestinal weight development is related to mortality. Thirty percent extra dietary ideal protein increased duodenum weight between 6 and 9 d of age. This was not further increased by the daily optimization of the dietary amino acid level and profile. The increased duodenum weights coincided with an improved BW gain. This indicates that duodenum weight may be important in facilitating BW gain in young broilers. Thus, it may be worthwhile to pay more attention to the relation between nutrition and duodenum weight and duodenum function in further studies. PMID:20548070

  6. MicroRNA-944 Affects Cell Growth by Targeting EPHA7 in Non-Small Cell Lung Cancer

    PubMed Central

    Liu, Minxia; Zhou, Kecheng; Cao, Yi

    2016-01-01

    MicroRNAs (miRNAs) have critical roles in lung tumorigenesis and development. To determine aberrantly expressed miRNAs involved in non-small cell lung cancer (NSCLC) and investigate pathophysiological functions and mechanisms, we firstly carried out small RNA deep sequencing in NSCLC cell lines (EPLC-32M1, A549 and 801D) and a human immortalized cell line 16HBE, we then studied miRNA function by cell proliferation and apoptosis. cDNA microarray, luciferase reporter assay and miRNA transfection were used to investigate interaction between the miRNA and target gene. miR-944 was significantly down-regulated in NSCLC and had many putative targets. Moreover, the forced expression of miR-944 significantly inhibited the proliferation of NSCLC cells in vitro. By integrating mRNA expression data and miR-944-target prediction, we disclosed that EPHA7 was a potential target of miR-944, which was further verified by luciferase reporter assay and microRNA transfection. Our data indicated that miR-944 targets EPHA7 in NSCLC and regulates NSCLC cell proliferation, which may offer a new mechanism underlying the development and progression of NSCLC. PMID:27681722

  7. A Study on Estimation on Flood Warning Trigger Rainfall in medium and small Stream Affected by Urban Effects

    NASA Astrophysics Data System (ADS)

    Youngseok, Song; Moojong, Park; JungHo, Lee; HeeSup, Lee

    2013-04-01

    As extreme floods occur frequently in recent years due to global climate changes, an in sudden local flooding of great volume and short duration is becoming the significant danger and loss of life and property in the Korean Peninsula as well as most parts of the world. The desire for living without hazardous damages grows these days, the city strategy to make the safer community has become an issue. Previously most of flood prevention efforts have been made for relatively large watersheds near to channel flow. However, as economical development and the expansion of city near medium and small stream, human casualty and property by flood occurs frequently. Therefore, to reduce the damage of human lives and property by flood, we develop an assessment method for flood warning trigger rainfall considering urban effect. Considering complex land use, HEC-HMS is used for rural area and SWMM is adopted for sewer networks runoff. And relationship between runoff and stream water level, HEC-RAS is accompanied with runoff results. Proposed flood warning trigger rainfall assessment method shows good agreement with gauged data and could be used for another case to mitigate damage. Acknowledgement: "This research was supported by a grant [NEMA-NH-2011-45] from the Natural Hazard Mitigation Research Group, National Emergency Management Agency of Korea." Keyword: HEC-HMS, HEC-RAS, critical precipitation, medium and small stream

  8. The Small Heat Shock Protein Hsp27 Affects Assembly Dynamics and Structure of Keratin Intermediate Filament Networks

    PubMed Central

    Kayser, Jona; Haslbeck, Martin; Dempfle, Lisa; Krause, Maike; Grashoff, Carsten; Buchner, Johannes; Herrmann, Harald; Bausch, Andreas R.

    2013-01-01

    The mechanical properties of living cells are essential for many processes. They are defined by the cytoskeleton, a composite network of protein fibers. Thus, the precise control of its architecture is of paramount importance. Our knowledge about the molecular and physical mechanisms defining the network structure remains scarce, especially for the intermediate filament cytoskeleton. Here, we investigate the effect of small heat shock proteins on the keratin 8/18 intermediate filament cytoskeleton using a well-controlled model system of reconstituted keratin networks. We demonstrate that Hsp27 severely alters the structure of such networks by changing their assembly dynamics. Furthermore, the C-terminal tail domain of keratin 8 is shown to be essential for this effect. Combining results from fluorescence and electron microscopy with data from analytical ultracentrifugation reveals the crucial role of kinetic trapping in keratin network formation. PMID:24138853

  9. Does kinship affect spatial organization in a small and isolated population of a solitary felid: The Eurasian lynx?

    PubMed

    Schmidt, Krzysztof; Davoli, Francesca; Kowalczyk, Rafał; Randi, Ettore

    2016-09-01

    Social organization in wild carnivores is mostly determined by patterns of family bonds, which may shape the degree of relatedness among individuals in the population. We studied kinship in a small and isolated population of a solitary carnivore, the Eurasian lynx (Lynx lynx) to evaluate its effect on spatial distribution of individuals. We investigated the relationship between spatial location and pair-wise kinship among 28 lynx individuals identified in 2004-2011 by telemetry, non-invasive sampling and genotyping with the use of 12 autosomal microsatellites in the Białowieża Primeval Forest, Poland. The average relatedness of the lynx population was relatively low (Lynch and Ritland's R = 0.03). Females were significantly more related to each other than males with other males. The inferred pedigree showed that the population was dominated by only 2 familial groups. We did not find significant correlations between the relatedness and the extent of home range overlap or the straight-line distances between the home ranges' central points. These results suggest that the dynamics of kinship in this solitary felid may not differ from the random mating processes described in social carnivores. Although the chances of random mating could be limited to a few resident males and females, the presence of unrelated floaters may provide a "breeding buffer" that may prevent an increase of relatedness and likely inbreeding in the population. This system is likely to fail in preserving genetic diversity in small, highly isolated populations; therefore, restoring habitat connectivity is crucial to ensure sufficient immigration from neighboring populations.

  10. IGS Minisatellites Useful for Race Differentiation in Colletotrichum lentis and a Likely Site of Small RNA Synthesis Affecting Pathogenicity.

    PubMed

    Durkin, Jonathan; Bissett, John; Pahlavani, Mohammadhadi; Mooney, Brent; Buchwaldt, Lone

    2015-01-01

    Colletotrichum lentis is a fungal pathogen of lentil in Canada but rarely reported elsewhere. Two races, Ct0 and Ct1, have been identified using differential lines. Our objective was to develop a PCR-probe differentiating these races. Sequences of the translation elongation factor 1α (tef1α), RNA polymerase II subunit B2 (rpb2), ATP citrate lyase subunit A (acla), and internal transcribed spacer (ITS) regions were monomorphic, while the intergenic spacer (IGS) region showed length polymorphisms at two minisatellites of 23 and 39 nucleotides (nt). A PCR-probe (39F/R) amplifying the 39 nt minisatellite was developed which subsequently revealed 1-5 minisatellites with 1-12 repeats in C. lentis. The probe differentiated race Ct1 isolates having 7, 9 or 7+9 repeats from race Ct0 having primarily 2 or 4 repeats, occasionally 5, 6, or 8, but never 7 or 9 repeats. These isolates were collected between 1991 and 1999. In a 2012 survey isolates with 2 and 4 repeats increased from 34% to 67%, while isolated with 7 or 9 repeats decreased from 40 to 4%, likely because Ct1 resistant lentil varieties had been grown. The 39 nt repeat was identified in C. gloeosporioides, C. trifolii, Ascochyta lentis, Sclerotinia sclerotiorum and Botrytis cinerea. Thus, the 39F/R PCR probe is not species specific, but can differentiate isolates based on repeat number. The 23 nt minisatellite in C. lentis exists as three length variants with ten sequence variations differentiating race Ct0 having 14 or 19 repeats from race Ct1 having 17 repeats, except for one isolate. RNA-translation of 23 nt repeats forms hairpins and has the appropriate length to suggest that IGS could be a site of small RNA synthesis, a hypothesis that warrants further investigation. Small RNA from fungal plant pathogens able to silence genes either in the host or pathogen thereby aiding infection have been reported. PMID:26340001

  11. IGS Minisatellites Useful for Race Differentiation in Colletotrichum lentis and a Likely Site of Small RNA Synthesis Affecting Pathogenicity

    PubMed Central

    Durkin, Jonathan; Bissett, John; Pahlavani, Mohammadhadi; Mooney, Brent; Buchwaldt, Lone

    2015-01-01

    Colletotrichum lentis is a fungal pathogen of lentil in Canada but rarely reported elsewhere. Two races, Ct0 and Ct1, have been identified using differential lines. Our objective was to develop a PCR-probe differentiating these races. Sequences of the translation elongation factor 1α (tef1α), RNA polymerase II subunit B2 (rpb2), ATP citrate lyase subunit A (acla), and internal transcribed spacer (ITS) regions were monomorphic, while the intergenic spacer (IGS) region showed length polymorphisms at two minisatellites of 23 and 39 nucleotides (nt). A PCR-probe (39F/R) amplifying the 39 nt minisatellite was developed which subsequently revealed 1–5 minisatellites with 1–12 repeats in C. lentis. The probe differentiated race Ct1 isolates having 7, 9 or 7+9 repeats from race Ct0 having primarily 2 or 4 repeats, occasionally 5, 6, or 8, but never 7 or 9 repeats. These isolates were collected between 1991 and 1999. In a 2012 survey isolates with 2 and 4 repeats increased from 34% to 67%, while isolated with 7 or 9 repeats decreased from 40 to 4%, likely because Ct1 resistant lentil varieties had been grown. The 39 nt repeat was identified in C. gloeosporioides, C. trifolii, Ascochyta lentis, Sclerotinia sclerotiorum and Botrytis cinerea. Thus, the 39F/R PCR probe is not species specific, but can differentiate isolates based on repeat number. The 23 nt minisatellite in C. lentis exists as three length variants with ten sequence variations differentiating race Ct0 having 14 or 19 repeats from race Ct1 having 17 repeats, except for one isolate. RNA-translation of 23 nt repeats forms hairpins and has the appropriate length to suggest that IGS could be a site of small RNA synthesis, a hypothesis that warrants further investigation. Small RNA from fungal plant pathogens able to silence genes either in the host or pathogen thereby aiding infection have been reported. PMID:26340001

  12. Weight loss is coupled with improvements to affective state in obese participants engaged in behavior change therapy based on incremental, self-selected "small changes".

    PubMed

    Paxman, Jenny R; Hall, Anna C; Harden, Charlotte J; O'Keeffe, Jean; Simper, Trevor N

    2011-05-01

    The aim of this study was to investigate the effects of a group behavior change intervention involving self-selected, contextualized, and mediated goal setting on anthropometric, affective, and dietary markers of health. It was hypothesized that the intervention would elicit changes consistent with accepted health recommendations for obese individuals. A rolling program of 12-week "Small Changes" interventions during 24 months recruited 71 participants; each program accommodated 10 to 13 adults (body mass index [BMI] ≥ 30 kg/m²). Fifty-eight participants completed Small Changes. Repeated measures were made at baseline, 6 and 12 weeks. Anthropometric measures included height and weight (to calculate BMI), body composition, waist circumference, and blood pressure. Affective state was monitored using relevant validated questionnaires. Dietary assessment used 3-day household measures food diaries with Schofield equations to monitor underreporting. Relevant blood measures were recorded throughout. Across the measurement period, Small Changes elicited a significant reduction in body weight (baseline, 102.95 ± 15.47 vs 12 weeks 100.09 ± 16.01 kg, P < .0005), coupled with associated significant improvements in BMI, body fat percentage, and waist circumference measures. There were additional significant positive changes in measures of affective state including general well-being (baseline, 58.92 ± 21.22 vs 12 weeks 78.04 ± 14.60, P < .0005) and total mood disturbance (baseline, 31.19 ± 34.03 vs 12 weeks 2.67 ± 24.96, P < .0005). Dietary changes that occurred were largely consistent with evidenced-based recommendations for weight management and included significant reductions in total energy intake and in fat and saturated fat as a proportion of energy. The Small Changes approach can elicit a range of health-orientated benefits for obese participants, and although further work is needed to ascertain the longevity of such effects, the outcomes from Small Changes are

  13. How the Performance of a Superconducting Magnet is affected by theConnection between a small cooler and the Magnet

    SciTech Connect

    Green, Michael A.

    2005-09-08

    As low temperature cryocoolers become more frequently used to cool superconducting magnets, it becomes increasingly apparent that the connection between the cooler and the magnet has an effect on the design and performance of the magnet. In general, the use of small coolers can be considered in two different temperature ranges; (1) from 3.8 to 4.8 K for magnet fabricated with LTS conductor and (2) from 18 to 35 K for magnets fabricated using HTS conductor. In general, both temperature ranges call for the use of a two-stage cooler. The best method for connecting a cooler to the magnet depends on a number of factors. The factors include: (1) whether the cooler must be used to cool down the magnet from room temperature, (2) whether the magnet must have one or more reservoirs of liquid cryogen to keep the magnet cold during a loss of cooling, and (3) constraints on the distance from the cooler cold heads and the magnet and its shield. Two methods for connecting low temperature coolers to superconducting magnets have been studied. The first method uses a cold strap to connect the cold heads directly to the loads. This method is commonly used for cryogen-free magnets. The second method uses a thermal siphon and liquid cryogens to make the connection between the load being cooled and the cold head. The two methods of transferring heat from the magnet to the cooler low temperature cold head are compared for the two temperature ranges given above.

  14. Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells.

    PubMed

    Fang, Shun; Gao, Hongyi; Tong, Yue; Yang, Jie; Tang, Ruixiang; Niu, Yuchun; Li, Man; Guo, Linlang

    2016-01-01

    Homeobox (HOX) transcript antisense RNA (HOTAIR), a long intergenic noncoding RNA (lincRNA), has been reported to play an oncogenic role in various cancers including small cell lung cancer (SCLC). However, it is not known whether HOTAIR can modulate chemoresistance in SCLC. The aim of this study is to investigate the roles of HOTAIR in chemoresistance of SCLC and its possible molecular mechanism. Knockdown of HOTAIR was carried out in SCLC multidrug-resistant cell lines (H69AR and H446AR) and the parental cell lines (H69 and H446) to assess its influence on chemoresistance. The results showed that downregulation of HOTAIR increased cell sensitivity to anticancer drugs through increasing cell apoptosis and cell cycle arrest, and suppressed tumor growth in vivo. Moreover, HOXA1 methylation increased in the resistant cells using bisulfite sequencing PCR. Depletion of HOTAIR reduced HOXA1 methylation by decreasing DNMT1 and DNMT3b expression. The interaction between HOTAIR and HOXA1 was validated by RNA immunoprecipitation. Taken together, our study suggested that HOTAIR mediates chemoresistance of SCLC by regulating HOXA1 methylation and could be utilized as a potential target for new adjuvant therapies against chemoresistance.

  15. Breeding scheme and maternal small RNAs affect the efficiency of transgenerational inheritance of a paramutation in mice.

    PubMed

    Yuan, Shuiqiao; Oliver, Daniel; Schuster, Andrew; Zheng, Huili; Yan, Wei

    2015-03-18

    Paramutations result from interactions between two alleles at a single locus, whereby one induces a heritable change in the other. Although common in plants, paramutations are rarely studied in animals. Here, we report a new paramutation mouse model, in which the paramutant allele was induced by an insertional mutation and displayed the "white-tail-tip" (WTT) phenotype. The paramutation phenotype could be transmitted across multiple generations, and the breeding scheme (intercrossing vs. outcrossing) drastically affected the transmission efficiency. Paternal (i.e., sperm-borne) RNAs isolated from paramutant mice could induce the paramutation phenotype, which, however, failed to be transmitted to subsequent generations. Maternal miRNAs and piRNAs appeared to have an inhibitory effect on the efficiency of germline transmission of the paramutation. This paramutation mouse model represents an important tool for dissecting the underlying mechanism, which should be applicable to the phenomenon of epigenetic transgenerational inheritance (ETI) in general. Mechanistic insights of ETI will help us understand how organisms establish new heritable epigenetic states during development, or in times of environmental or nutritional stress.

  16. Factors Affecting Process Temperature and Biogas Production in Small-scale Rural Biogas Digesters in Winter in Northern Vietnam.

    PubMed

    Pham, C H; Vu, C C; Sommer, S G; Bruun, S

    2014-07-01

    This study investigated the main factors influencing digester temperature and methods to reduce heat losses during the cold season in the subtropics. Four composite digesters (two insulated and two uninsulated) were buried underground to measure their internal temperature (°C) at a depth of 140 cm and 180 cm, biogas production and methane (CH4) concentration in biogas from August to February. In parallel the temperature of the air (100 cm above ground), in the slurry mixing tank and in the soil (10, 100, 140, and 180 cm depth) was measured by thermocouple. The influent amount was measured daily and the influent chemical composition was measured monthly during the whole experimental period. Seasonal variations in air temperature significantly affected the temperature in the soil, mixing tank and digester. Consequently, biogas production, which is temperature dependent, was influenced by the season. The main factors determining the internal temperature in the digesters were insulation with Styrofoam, air temperature and temperature of slurry in the mixing tank. Biogas production is low due to the cold climate conditions in winter in Northern Vietnam, but the study proved that storing slurry in the mixing tank until its temperature peak at around 14:00 h will increase the temperature in the digester and thus increase potential biogas production. Algorithms are provided linking digester temperature to the temperature of slurry in the mixing tank.

  17. Breeding scheme and maternal small RNAs affect the efficiency of transgenerational inheritance of a paramutation in mice

    PubMed Central

    Yuan, Shuiqiao; Oliver, Daniel; Schuster, Andrew; Zheng, Huili; Yan, Wei

    2015-01-01

    Paramutations result from interactions between two alleles at a single locus, whereby one induces a heritable change in the other. Although common in plants, paramutations are rarely studied in animals. Here, we report a new paramutation mouse model, in which the paramutant allele was induced by an insertional mutation and displayed the “white-tail-tip” (WTT) phenotype. The paramutation phenotype could be transmitted across multiple generations, and the breeding scheme (intercrossing vs. outcrossing) drastically affected the transmission efficiency. Paternal (i.e., sperm-borne) RNAs isolated from paramutant mice could induce the paramutation phenotype, which, however, failed to be transmitted to subsequent generations. Maternal miRNAs and piRNAs appeared to have an inhibitory effect on the efficiency of germline transmission of the paramutation. This paramutation mouse model represents an important tool for dissecting the underlying mechanism, which should be applicable to the phenomenon of epigenetic transgenerational inheritance (ETI) in general. Mechanistic insights of ETI will help us understand how organisms establish new heritable epigenetic states during development, or in times of environmental or nutritional stress. PMID:25783852

  18. Factors Affecting Process Temperature and Biogas Production in Small-scale Rural Biogas Digesters in Winter in Northern Vietnam.

    PubMed

    Pham, C H; Vu, C C; Sommer, S G; Bruun, S

    2014-07-01

    This study investigated the main factors influencing digester temperature and methods to reduce heat losses during the cold season in the subtropics. Four composite digesters (two insulated and two uninsulated) were buried underground to measure their internal temperature (°C) at a depth of 140 cm and 180 cm, biogas production and methane (CH4) concentration in biogas from August to February. In parallel the temperature of the air (100 cm above ground), in the slurry mixing tank and in the soil (10, 100, 140, and 180 cm depth) was measured by thermocouple. The influent amount was measured daily and the influent chemical composition was measured monthly during the whole experimental period. Seasonal variations in air temperature significantly affected the temperature in the soil, mixing tank and digester. Consequently, biogas production, which is temperature dependent, was influenced by the season. The main factors determining the internal temperature in the digesters were insulation with Styrofoam, air temperature and temperature of slurry in the mixing tank. Biogas production is low due to the cold climate conditions in winter in Northern Vietnam, but the study proved that storing slurry in the mixing tank until its temperature peak at around 14:00 h will increase the temperature in the digester and thus increase potential biogas production. Algorithms are provided linking digester temperature to the temperature of slurry in the mixing tank. PMID:25050049

  19. Factors Affecting Process Temperature and Biogas Production in Small-scale Rural Biogas Digesters in Winter in Northern Vietnam

    PubMed Central

    Pham, C. H.; Vu, C. C.; Sommer, S. G.; Bruun, S.

    2014-01-01

    This study investigated the main factors influencing digester temperature and methods to reduce heat losses during the cold season in the subtropics. Four composite digesters (two insulated and two uninsulated) were buried underground to measure their internal temperature (°C) at a depth of 140 cm and 180 cm, biogas production and methane (CH4) concentration in biogas from August to February. In parallel the temperature of the air (100 cm above ground), in the slurry mixing tank and in the soil (10, 100, 140, and 180 cm depth) was measured by thermocouple. The influent amount was measured daily and the influent chemical composition was measured monthly during the whole experimental period. Seasonal variations in air temperature significantly affected the temperature in the soil, mixing tank and digester. Consequently, biogas production, which is temperature dependent, was influenced by the season. The main factors determining the internal temperature in the digesters were insulation with Styrofoam, air temperature and temperature of slurry in the mixing tank. Biogas production is low due to the cold climate conditions in winter in Northern Vietnam, but the study proved that storing slurry in the mixing tank until its temperature peak at around 14:00 h will increase the temperature in the digester and thus increase potential biogas production. Algorithms are provided linking digester temperature to the temperature of slurry in the mixing tank. PMID:25050049

  20. Small scale hydrology in a pristine and an affected peatland: effects of flood water on soil biogeochemistry

    NASA Astrophysics Data System (ADS)

    Vorenhout, Michel; Cusell, Casper

    2014-05-01

    Many peatlands have a water regime of fluctuating water levels. Flooding of peatsoils occurs in several Dutch peatlands. The quality of this floodwater is important for the ecological value of the peatlands. Well known are the eutrophying effects of polluted flood water on the N- and P- limited vegetation. Nutrients can, however, also be released from the soil; anoxic conditions are known to release Fe-bound phosphorus. It is therefore important to focus on small scale hydrology in projects where water levels are manipulated and floodings are induced. Three types of peatlands have been the subject of two separate studies on hydrology, ecological value and soil biogeochemistry. Two pristine sites and one recently restored flood water storage basin were monitored during 2009-2013. These three sites cover the natural range of peatsoils: from floating fens to degraded and fixed peat soils. All sites have peat as the main soil type, but the age and typology differs. The two pristine sites, the Wieden and Weerribben, are characterized by limited natural and/or induced flooding events. These sites have peaty soils. The soils in the Wieden are fixed to the sandy substrate below, the peaty soils in the Weerribben are completely floating on a water layer. The ecological value of the Wieden and the Weerribben is high, but their value may decline due to low variation in water levels. The third site, the Onlanden area, is a large created storm water storage basin. The Onlanden area is a former agricultural area, inhabited since the Medieval period. It has a fixed and rather degraded peaty soil. Large scale restoration of water inlets and dams has created an area that will get flooded at regular intervals. The Onlanden was the subject of an archaeological monitoring project. All sites were equipped with monitoring stations for local and regional water levels, soil moisture and soil redox potential as the indicator for the local biogeochemistry. Cusell et al (2013) studied the

  1. RNA interference-mediated silencing of a Halloween gene spookier affects nymph performance in the small brown planthopper Laodelphax striatellus.

    PubMed

    Jia, Shuang; Wan, Pin-Jun; Zhou, Li-Tao; Mu, Li-Li; Li, Guo-Qing

    2015-04-01

    Post-embryonic development of insects is highly dependent on ecdysteroid hormone 20-hydroxyecdysone. Halloween gene spookier (spok, cyp307a2) has been documented to be involved in ecdysteroidogenesis in Drosophila melanogaster and Bombyx mori. We describe here the cloning and characterization of Halloween gene spookier (Lsspok, Lscyp307a2) in the small brown planthopper Laodelphax striatellus, a hemipteran insect species. LsSPOK has three insect-conserved P450 motifs, that is, Helix-K, PERF motif and heme-binding domain. Temporal and spatial expression patterns of Lsspok were evaluated by quantitative polymerase chain reaction. Through the fouth-instar and the early fifth-instar stages, Lsspok showed two expression peaks in the second- and fifth-day fourth-instar nymphs, and two troughs in the first-day fourth and fifth instars. On day 5 of the fourth-instar nymphs, Lsspok clearly had a high transcript level in the thorax where prothoracic glands were located. Dietary introduction of double-stranded RNA of Lsspok in the nymph stage successfully knocked down the target gene, decreased expression level of ecdysone receptor (LsEcR) gene, caused nymphal lethality and delayed development. Ingestion of 20-hydroxyecdysone in Lsspok-dsRNA-exposed nymphs did not increase Lsspok expression level, but almost completely rescued the LsEcR mRNA level and relieved the negative effects on survival and development. Thus, our data suggest that the ecdysteroidogenic pathway is conserved in insects and LsSPOK is responsible for specific steps in ecdysteroidogenesis in L. striatellus. PMID:24282064

  2. RNA interference-mediated silencing of a Halloween gene spookier affects nymph performance in the small brown planthopper Laodelphax striatellus.

    PubMed

    Jia, Shuang; Wan, Pin-Jun; Zhou, Li-Tao; Mu, Li-Li; Li, Guo-Qing

    2015-04-01

    Post-embryonic development of insects is highly dependent on ecdysteroid hormone 20-hydroxyecdysone. Halloween gene spookier (spok, cyp307a2) has been documented to be involved in ecdysteroidogenesis in Drosophila melanogaster and Bombyx mori. We describe here the cloning and characterization of Halloween gene spookier (Lsspok, Lscyp307a2) in the small brown planthopper Laodelphax striatellus, a hemipteran insect species. LsSPOK has three insect-conserved P450 motifs, that is, Helix-K, PERF motif and heme-binding domain. Temporal and spatial expression patterns of Lsspok were evaluated by quantitative polymerase chain reaction. Through the fouth-instar and the early fifth-instar stages, Lsspok showed two expression peaks in the second- and fifth-day fourth-instar nymphs, and two troughs in the first-day fourth and fifth instars. On day 5 of the fourth-instar nymphs, Lsspok clearly had a high transcript level in the thorax where prothoracic glands were located. Dietary introduction of double-stranded RNA of Lsspok in the nymph stage successfully knocked down the target gene, decreased expression level of ecdysone receptor (LsEcR) gene, caused nymphal lethality and delayed development. Ingestion of 20-hydroxyecdysone in Lsspok-dsRNA-exposed nymphs did not increase Lsspok expression level, but almost completely rescued the LsEcR mRNA level and relieved the negative effects on survival and development. Thus, our data suggest that the ecdysteroidogenic pathway is conserved in insects and LsSPOK is responsible for specific steps in ecdysteroidogenesis in L. striatellus.

  3. Use of portable antennas to estimate abundance of PIT-tagged fish in small streams: Factors affecting detection probability

    USGS Publications Warehouse

    O'Donnell, Matthew J.; Horton, Gregg E.; Letcher, Benjamin H.

    2010-01-01

    Portable passive integrated transponder (PIT) tag antenna systems can be valuable in providing reliable estimates of the abundance of tagged Atlantic salmon Salmo salar in small streams under a wide range of conditions. We developed and employed PIT tag antenna wand techniques in two controlled experiments and an additional case study to examine the factors that influenced our ability to estimate population size. We used Pollock's robust-design capture–mark–recapture model to obtain estimates of the probability of first detection (p), the probability of redetection (c), and abundance (N) in the two controlled experiments. First, we conducted an experiment in which tags were hidden in fixed locations. Although p and c varied among the three observers and among the three passes that each observer conducted, the estimates of N were identical to the true values and did not vary among observers. In the second experiment using free-swimming tagged fish, p and c varied among passes and time of day. Additionally, estimates of N varied between day and night and among age-classes but were within 10% of the true population size. In the case study, we used the Cormack–Jolly–Seber model to examine the variation in p, and we compared counts of tagged fish found with the antenna wand with counts collected via electrofishing. In that study, we found that although p varied for age-classes, sample dates, and time of day, antenna and electrofishing estimates of N were similar, indicating that population size can be reliably estimated via PIT tag antenna wands. However, factors such as the observer, time of day, age of fish, and stream discharge can influence the initial and subsequent detection probabilities.

  4. Calculating impact factor: how bibliographical classification of journal items affects the impact factor of large and small journals.

    PubMed

    Golubic, Rajna; Rudes, Mihael; Kovacic, Natasa; Marusic, Matko; Marusic, Ana

    2008-03-01

    As bibliographical classification of published journal items affects the denominator in this equation, we investigated how the numerator and denominator of the impact factor (IF) equation were generated for representative journals in two categories of the Journal Citation Reports (JCR). We performed a full text search of the 1st-ranked journal in 2004 JCR category "Medicine, General and Internal" (New England Journal of Medicine, NEJM, IF = 38.570) and 61st-ranked journal (Croatian Medical Journal, CMJ, IF = 0.690), 1st-ranked journal in category "Multidisciplinary Sciences" (Nature, IF = 32.182) and journal with a relative rank of CMJ (Anais da Academia Brasileira de Ciencias, AABC, IF = 0.435). Large journals published more items categorized by Web of Science (WoS) as non-research items (editorial material, letters, news, book reviews, bibliographical items, or corrections): 63% out of total 5,193 items in Nature and 81% out of 3,540 items in NEJM, compared with 31% out of 283 items in CMJ and only 2 (2%) out of 126 items in AABC. Some items classified by WoS as non-original contained original research data (9.5% in Nature, 7.2% in NEJM, 13.7% in CMJ and none in AABC). These items received a significant number of citations: 6.9% of total citations in Nature, 14.7% in NEJM and 18.5% in CMJ. IF decreased for all journals when only items presenting original research and citations to them were used for IF calculation. Regardless of the journal's size or discipline, publication of non-original research and its classification by the bibliographical database have an effect on both numerator and denominator of the IF equation.

  5. Hydrological modelling in small, semi-arid catchments of south-eastern Australia: reforestation affects groundwater but not streamflow

    NASA Astrophysics Data System (ADS)

    Dean, Joshua; Camporese, Matteo; Grover, Samantha; Webb, John; Dresel, Evan; Daly, Edoardo

    2015-04-01

    Land use has a strong influence on evapotranspiration (ET) and thus a large effect on catchment hydrology. The dearth of data from arid and semi-arid catchments limits the understanding of the possible effects of land-use and land-use change on water resources in these environments. Here we use three years of rainfall, streamflow, and groundwater level measurements to estimate the water balance components in two small, adjacent ephemeral Australian catchments, one predominantly covered with a young eucalypt plantation and the other primarily dedicated to grazing pasture. The average annual rainfall for the study area is ~670 mm, with ET greatly exceeding rainfall for most of the year, excepting the winter months of May through September. The paired catchments are similar in size and are situated on the same Devonian granitic geology. Land-use is the most striking difference between the catchments; this allows for a strong hydrological comparison of the eucalypt catchment (planted in 2008) with the pasture catchment. The majority of data is available from 2009 until present, although historical bi-monthly groundwater level data exists back to 1986. We focus on 2010-2012, and we have maximum data for 2012, including eddy covariance and sap flow measurements. The integrated hydrological model CATHY was calibrated and validated against the data in the two catchments for 2011 and 2012. The water balances estimated from both data and model show a significant increase in ET in the eucalypt plantation catchment at the expense of groundwater storage: ET accounted for 95-97% of rainfall in the pasture catchment and 104-110% in the eucalypt catchment across the three years studied. Direct measurements of ET in 2012 confirm the water balance values. However, streamflow was more or less constant at 3-4% of rainfall in both catchments for the study period. The model results suggest that this is because streamflow is generated primarily from surface runoff, showing that land use

  6. Student Government.

    ERIC Educational Resources Information Center

    Morrow, Joyce

    Materials for running a student government program at the junior high school level are provided in three general sections. Section 1 is a description of student government operations. Topics covered include student government responsibilities and activities, student council meeting procedures, parliamentary rules, responsibilities of the…

  7. Processing of soybean meal and 00-rapeseed meal reduces protein digestibility and pig growth performance but does not affect nitrogen solubilization along the small intestine.

    PubMed

    Hulshof, T G; van der Poel, A F B; Hendriks, W H; Bikker, P

    2016-06-01

    An experiment was conducted to determine the effects of processing of soybean meal (SBM) and 00-rapeseed meal (RSM) on N solubilization in chyme, CP digestibility along the small intestine, metabolic load as determined by organ weight, body composition, and growth performance in growing pigs. The SBM and RSM were processed by secondary toasting (at 95°C for 30 min) in the presence of lignosulfonate, resulting in processed SBM (pSBM) and processed RSM (pRSM) as a model for overprocessed protein sources. Fifty-four growing pigs were each fed 1 of the 6 experimental diets. Four of the diets contained SBM, pSBM, RSM, or pRSM as the sole protein source. The remaining 2 experimental diets contained pSBM or pRSM and were supplemented with crystalline AA to the same standardized ileal digestible AA levels as the SBM or RSM diet. Pigs were slaughtered at 40 kg, and organ weights were recorded. The organs plus blood and empty carcass were analyzed for CP content. The small intestine was divided into 3 segments, and chyme samples were taken from the last meter of each segment. Chyme of the SBM, pSBM, RSM, and pRSM diets was centrifuged to separate the soluble and insoluble fractions, and N content was determined in the latter. The amount of insoluble N as a fraction of N in chyme at each small intestinal segment was not affected by processing. Diet type, comprising effects of processing and supplementing crystalline AA, affected ( < 0.05) the G:F and standardized ileal digestibility (SID) of CP. Processing reduced G:F from 0.56 to 0.38 for SBM and 0.49 to 0.40 for RSM, whereas supplementing crystalline AA increased G:F to the level of the SBM and RSM diets. Processing reduced the SID of CP from 87.2% to 69.2% for SBM and 71.0% to 52.2% for RSM. Diet type affected ( < 0.05) the CP content in the empty body, with processing reducing this content from 170 to 144 g/kg empty BW for SBM and 157 to 149 g/kg empty BW for RSM and supplementing crystalline AA restoring this content

  8. Reinventing Government.

    ERIC Educational Resources Information Center

    Osborne, David T.

    1993-01-01

    Throughout all levels of American government, a shift is taking place from the rigid, wasteful, centralized bureaucracies of the industrial era to the more flexible, entrepreneurial, decentralized government needed to succeed in today's world. This shift has been brought about by an unprecedented, ongoing fiscal crisis that has created a sudden…

  9. Remaking Governance.

    ERIC Educational Resources Information Center

    Carver, John

    2000-01-01

    The Policy Governance model's philosophical foundations lie in Rousseau's social contract, Greenleaf's servant-leadership, and modern management theory. Policy Governance stresses primacy of the owner-representative role; full-board authority; superintendents as chief executive officers; authoritative prescription of "ends," bounded freedom for…

  10. Policing Governance.

    ERIC Educational Resources Information Center

    Schuster, Jack H.

    1991-01-01

    The American Association of University Professors' (AAUP) new policy authorizing sanctions against colleges when investigation discloses serious departures from accepted governance norms is examined. Issues discussed include the existence and general relevance of governance norms, evidence of violation of those standards, and the AAUP's right to…

  11. Phenylalanine flux and gastric emptying are not affected by replacement of casein with whey protein in the diet of adult cats consuming frequent small meals

    PubMed Central

    2014-01-01

    Background Decreasing the rate of protein emptying from the stomach may improve efficiency of utilization of dietary amino acids for protein deposition. Some studies in rats and humans have shown casein to be more slowly released from the stomach than whey protein. To test if casein induces a slower rate of gastric emptying in cats than whey protein, L-[1-13C]phenylalanine (Phe) was dosed orally into 9 adult cats to estimate gastric emptying and whole-body Phe flux. Results Concentrations of indispensable amino acids in plasma were not significantly affected by dietary protein source. First-pass splanchnic extraction of Phe was not different between diets and averaged 50% (SEM = 3.8%). The half-time for gastric emptying averaged 9.9 min with casein and 10.3 min with whey protein, and was not significantly different between diets (SEM = 1.7 min). Phenylalanine fluxes were 45.3 and 46.5 μmol/(min · kg) for casein- and whey-based diets, respectively (SEM = 4.7 μmol/(min · kg)). Conclusions In adult cats fed frequent small meals, the replacement of casein with whey protein in the diet does not affect supply or utilization of amino acids. These two milk proteins appear to be equally capable of meeting the dietary amino acid needs of cats. PMID:25266643

  12. Report on the suitability of Class 6, U.S. government security repositories for the storage of small quantities of high explosives

    SciTech Connect

    Harry, H.H.; Murk, D.

    1998-03-01

    The Explosives Review Committee initiated a study into the safety aspects of the common practice of storing small amounts (< 10 grams per drawer) of high explosives in safes. Although storage of HE in older asbestos lined safes was permitted, the newer style Class 6 Security safes are an unacceptable repository for even very small amounts of HE without the use of a blast mitigating insert. The authors have developed a drawer liner in the form of a laminated Lexan, foam, plywood box that will withstand the blast and contain the fragments from up to 10 grams of high explosives. This liner will fit into the drawer of any existing safe. The liner will provide blast and fragment protection, and the safe will provide security protection. This report describes the testing of modern safes and the performance of the liner insert.

  13. Renewing governance.

    PubMed

    Loos, Gregory P

    2003-01-01

    Globalization's profound influence on social and political institutions need not be negative. Critics of globalization have often referred to the "Impossible Trinity" because decision-making must 1. respect national sovereignty, 2. develop and implement firm regulation, and 3. allow capital markets to be as free as possible. To many, such goals are mutually exclusive because history conditions us to view policy-making and governance in traditional molds. Thus, transnational governance merely appears impossible because current forms of governance were not designed to provide it. The world needs new tools for governing, and its citizens must seize the opportunity to help develop them. The rise of a global society requires a greater level of generality and inclusion than is found in most policy bodies today. Politicians need to re-examine key assumptions about government. States must develop ways to discharge their regulatory responsibilities across borders and collaborate with neighboring jurisdictions, multilateral bodies, and business. Concepts such as multilateralism and tripartism show great promise. Governments must engage civil society in the spirit of shared responsibility and democratic decision-making. Such changes will result in a renewal of the state's purpose and better use of international resources and expertise in governance. PMID:17208717

  14. Small-Scale Variation in Fuel Loads Differentially Affects Two Co-Dominant Bunchgrasses in a Species-Rich Pine Savanna

    PubMed Central

    Gagnon, Paul R.; Harms, Kyle E.; Platt, William J.; Passmore, Heather A.; Myers, Jonathan A.

    2012-01-01

    Ecological disturbances frequently control the occurrence and patterning of dominant plants in high-diversity communities like C4 grasslands and savannas. In such ecosystems disturbance-related processes can have important implications for species, and for whole communities when those species are dominant, yet mechanistic understanding of such processes remains fragmentary. Multiple bunchgrass species commonly co-dominate disturbance-dependent and species-rich pine savannas, where small-scale fuel heterogeneity may influence bunchgrass survival and growth following fires. We quantified how fire in locally varying fuel loads influenced dynamics of dominant C4 bunchgrasses in a species-rich pine savanna in southeastern Louisiana, USA. We focused on two congeneric, co-dominant species (Schizachyrium scoparium and S. tenerum) with similar growth forms, functional traits and reproductive strategies to highlight effects of fuel heterogeneity during fires. In experimental plots with either reduced or increased fuels versus controls with unmanipulated fuels, we compared: 1) bunchgrass damage and 2) mortality from fires; 3) subsequent growth and 4) flowering. Compared to controls, fire with increased fuels caused greater damage, mortality and subsequent flowering, but did not affect post-fire growth. Fire with reduced fuels had no effect on any of the four measures. The two species responded differently to fire with increased fuels – S. scoparium incurred measurably more damage and mortality than S. tenerum. Logistic regression indicated that the larger average size of S. tenerum tussocks made them resistant to more severe burning where fuels were increased. We speculate that locally increased fuel loading may be important in pine savannas for creating colonization sites because where fuels are light or moderate, dominant bunchgrasses persist through fires. Small-scale heterogeneity in fires, and differences in how species tolerate fire may together promote shared local

  15. Changing Dermatopathology Protocols for Processing Small Skin Biopsies: Decreases in Slide Quantity Does Not Affect Patient Care and Allows for Optimal Efficiency.

    PubMed

    Mudaliar, Kumaran; Speiser, Jodi; Hutchens, Kelli A

    2016-06-01

    In dermatopathology, no standard protocol exists for processing small biopsy specimens. In our original protocol, 2 routine initial slides per biopsy were prepared. For 1003 biopsies, we noted how often the second slide helped in diagnosis or eliminated the need for additional deeper sections. After obtaining these data, we switched to processing only 1 initial slide (new protocol) and again evaluated 1003 biopsies. During the original protocol, the second slide never helped to make a diagnosis that was not apparent on the first slide. When deeper sections were ordered (10.4% of cases), they helped in the diagnosis 34.6% of the time. In the new protocol, deeper sections were ordered in 15.9% of cases and helped in the diagnosis 32.7% of the time when ordered. Comparing rates of deeper sections ordered showed no significant difference for benign, inflammatory/reactive, and premalignant/malignant groups (P > 0.1). However, there was a significant increase in deeper sections ordered for melanocytic lesions from 16.9% to 32.3% (P < 0.05). Also, a significantly greater percentage of punch biopsies (31.5% and 42.0% in the respective protocols) required deeper sections than shave biopsies (7.4% and 12.6% in the respective protocols). Switching protocols, the estimated annual cost savings is $2890. The majority of cases at our institution are properly diagnosed using only 1 slide. From our study findings, we conclude that 1 slide preparation for small biopsies is the best practice for our institution and one that does not affect diagnostic accuracy, reduces costs, and helps in effective time management. PMID:27101126

  16. Factors Affecting the Risk of Brain Metastasis in Small Cell Lung Cancer With Surgery: Is Prophylactic Cranial Irradiation Necessary for Stage I-III Disease?

    SciTech Connect

    Gong Linlin; Wang, Q.I.; Zhao Lujun; Yuan Zhiyong; Li Ruijian; Wang Ping

    2013-01-01

    Purpose: The use of prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC) with surgical resection has not been fully identified. This study undertook to assess the factors affecting the risk of brain metastases in patients with stage I-III SCLC after surgical resection. The implications of PCI treatment for these patients are discussed. Methods and Materials: One hundred twenty-six patients treated with surgical resection for stage I-III SCLC from January 1998-December 2009 were retrospectively analyzed to elucidate the risk factors of brain metastases. Log-rank test and Cox regression model were used to determine the risk factors of brain metastases. Results: The median survival time for this patient population was 34 months, and the 5-year overall survival rate was 34.9%. For the whole group, 23.0% (29/126) of the patients had evidence of metastases to brain. Pathologic stage not only correlated with overall survival but also significantly affected the risk of brain metastases. The 5-year survival rates for patients with pathologic stages I, II, and III were 54.8%, 35.6%, and 14.1%, respectively (P=.001). The frequency of brain metastases in patients with pathologic stages I, II, and III were 6.25% (2/32), 28.2% (11/39), and 29.1% (16/55) (P=.026), respectively. A significant difference in brain metastases between patients with complete resection and incomplete resection was also observed (20.5% vs 42.9%, P=.028). The frequency of brain metastases was not found to be correlated with age, sex, pathologic type, induction chemotherapy, adjuvant chemotherapy, or adjuvant radiation therapy. Conclusions: Stage I SCLC patients with complete resection had a low incidence of brain metastases and a favorable survival rate. Stage II-III disease had a higher incidence of brain metastases. Thus, PCI might have a role for stage II-III disease but not for stage I disease.

  17. Cloning a balanced t(9;11)(p24;q23.1) chromosomal translocation breakpoint segregating with bipolar affective disorder in a small pedigree

    SciTech Connect

    Duggan, D.J.; Baysal, B.E.; Gollin, S.M.

    1994-09-01

    A small multigenerational pedigree was previously identified in which a balanced 9;11 chromosomal translocation was cosegregating with bipolar affective disorder. We hypothesize that genes or gene regulatory sequences disrupted by the translocation are contributing to bipolar affective disorder in a dominant fashion. The general strategy involves (1) using somatic cell hybrids containing the derivative 9 or 11 chromosomes to identify the closest chromosome 9 and 11 flanking markers, (2) using the nearest markers as PCR and hybridization probes to isolate both normal DNA (YAC) and patient DNA (cosmid) adjacent to and incorporating the translocation breakpoint, and (3) identifying expressed sequences in the genomic DNA that may be disrupted by the translocation. From a fusion of the translocation patient cell line and a recipient hamster cell line, somatic cell hybrids were isolated which contain either the human derivative 9 or derivative 11 chromosome. Using PCR-based STS assays with these hybrids, the location of the translocation breakpoint was localized to an estimated 500 kb region at chromosome 11 band q23.1 and a 1 cM region in 9 band p24 (more telomeric than originally reported). From a large set of CEPH and Roswell Park yeast artificial chromosomes (YACs), six chromosome 11 YACs spanning the 11q23.1 breakpoint have now been identified. A combination of pulsed field gel eletrophoresis and YAC mapping has narrowed the chromosome 11 region to less than 430 kb. Current efforts are focused on generating new chromosome 11 probes within the flanking markers, mapping these probes back to the der(9) and der(11) containing hybrids and the chromosome 11 YAC mapping panel. As the region is physically narrowed, we will identify candidate genes whose expression may be altered by this t(9:11) translocation.

  18. Cats are not small dogs: is there an immunological explanation for why cats are less affected by arthropod-borne disease than dogs?

    PubMed

    Day, Michael J

    2016-09-20

    It is widely recognized that cats appear to be less frequently affected by arthropod-borne infectious diseases than dogs and share fewer zoonotic pathogens with man. This impression is supported by the relative lack of scientific publications related to feline vector-borne infections. This review explores the possible reasons for the difference between the two most common small companion animal species, including the hypothesis that cats might have a genetically-determined immunological resistance to arthropod vectors or the microparasites they transmit. A number of simple possibilities might account for the lower prevalence of these diseases in cats, including factors related to the lifestyle and behaviour of the cat, lesser spend on preventative healthcare for cats and reduced opportunities for research funding for these animals. The dog and cat have substantially similar immune system components, but differences in immune function might in part account for the markedly distinct prevalence and clinicopathological appearance of autoimmune, allergic, idiopathic inflammatory, immunodeficiency, neoplastic and infectious diseases in the two species. Cats have greater genetic diversity than dogs with much lower linkage disequilibrium in feline compared with canine breed groups. Immune function is intrinsically related to the nature of the intestinal microbiome and subtle differences between the canine and feline microbial populations might also impact on immune function and disease resistance. The reasons for the apparent lesser susceptibility of cats to arthropod-borne infectious diseases are likely to be complex, but warrant further investigation.

  19. Cats are not small dogs: is there an immunological explanation for why cats are less affected by arthropod-borne disease than dogs?

    PubMed

    Day, Michael J

    2016-01-01

    It is widely recognized that cats appear to be less frequently affected by arthropod-borne infectious diseases than dogs and share fewer zoonotic pathogens with man. This impression is supported by the relative lack of scientific publications related to feline vector-borne infections. This review explores the possible reasons for the difference between the two most common small companion animal species, including the hypothesis that cats might have a genetically-determined immunological resistance to arthropod vectors or the microparasites they transmit. A number of simple possibilities might account for the lower prevalence of these diseases in cats, including factors related to the lifestyle and behaviour of the cat, lesser spend on preventative healthcare for cats and reduced opportunities for research funding for these animals. The dog and cat have substantially similar immune system components, but differences in immune function might in part account for the markedly distinct prevalence and clinicopathological appearance of autoimmune, allergic, idiopathic inflammatory, immunodeficiency, neoplastic and infectious diseases in the two species. Cats have greater genetic diversity than dogs with much lower linkage disequilibrium in feline compared with canine breed groups. Immune function is intrinsically related to the nature of the intestinal microbiome and subtle differences between the canine and feline microbial populations might also impact on immune function and disease resistance. The reasons for the apparent lesser susceptibility of cats to arthropod-borne infectious diseases are likely to be complex, but warrant further investigation. PMID:27646278

  20. Development and implementation of a finite element solution of the coupled neutron transport and thermoelastic equations governing the behavior of small nuclear assemblies

    NASA Astrophysics Data System (ADS)

    Wilson, Stephen Christian

    Small, highly enriched reactors designed for weapons effects simulations undergo extreme thermal transients during pulsed operations. The primary shutdown mechanism of these reactors---thermal expansion of fuel material---experiences an inertial delay resulting in a different value for the fuel temperature coefficient of reactivity during pulse operation as compared to the value appropriate for steady-state operation. The value appropriate for pulsed operation may further vary as a function of initial reactivity addition. Here we design and implement a finite element numerical method to predict the pulse operation behavior of Sandia Pulsed Reactor (SPR) II, SPR III, and a hypothetical spherical assembly with identical fuel properties without using operationally observed data in our model. These numerical results are compared to available SPR II and SPR III operational data. The numerical methods employed herein may be modified and expanded in functionality to provide both accurate characterization of the behavior of fast burst reactors of any common geometry or isotropic fuel material in the design phase, as well as a computational tool for general coupled thermomechanical-neutronics behavior in the solid state for any reactor type.

  1. Government Regulatory

    NASA Astrophysics Data System (ADS)

    Becker, Katie

    Government regulation of food products, food processing, and food preparation is imperative in bringing an unadulterated, nonmisleading, and safe food product to market and is relevant to all areas of food science, including engineering, processing, chemistry, and microbiology. The liability associated with providing consumers with an adulterated or substandard product cannot only tarnish a company's name and reputation, but also impose substantial financial repercussions on the company and those individuals who play an active role in the violation. In order for a company to fully comply with the relevant food laws (both federal and state), an intimate knowledge of food science is required. Individuals knowledgeable in food science play an integral role not only in implementing and counseling food companies/processors to ensure compliance with government regulations, but these individuals are also necessary to the state and federal governments that make and enforce the relevant laws and regulators.

  2. Understanding 'anticipatory governance'.

    PubMed

    Guston, David H

    2014-04-01

    Anticipatory governance is 'a broad-based capacity extended through society that can act on a variety of inputs to manage emerging knowledge-based technologies while such management is still possible'. It motivates activities designed to build capacities in foresight, engagement, and integration--as well as through their production ensemble. These capacities encourage and support the reflection of scientists, engineers, policy makers, and other publics on their roles in new technologies. This article reviews the early history of the National Nanotechnology Initiative in the United States, and it further explicates anticipatory governance through exploring the genealogy of the term and addressing a set of critiques found in the literature. These critiques involve skepticism of three proximities of anticipatory governance: to its object, nanotechnology, which is a relatively indistinct one; to the public, which remains almost utterly naive toward nanotechnology; and to technoscience itself, which allegedly renders anticipatory governance complicit in its hubris. The article concludes that the changing venues and the amplification within them of the still, small voices of folks previously excluded from offering constructive visions of futures afforded by anticipatory governance may not be complete solutions to our woes in governing technology, but they certainly can contribute to bending the long arc of technoscience more toward humane ends. PMID:24941612

  3. Small Variations in Early-Life Environment Can Affect Coping Behaviour in Response to Foraging Challenge in the Three-Spined Stickleback

    PubMed Central

    2016-01-01

    Context An increasing concern in the face of human expansion throughout natural habitats is whether animal populations can respond adaptively when confronted with challenges like environmental change and novelty. Behavioural flexibility is an important factor in estimating the adaptive potential of both individuals and populations, and predicting the degree to which they can cope with change. Study Design This study on the three-spined stickleback (Gasterosteus aculeatus) is an empiric illustration of the degree of behavioural variation that can emerge between semi-natural systems within only a single generation. Wild-caught adult sticklebacks (P, N = 400) were randomly distributed in equal densities over 20 standardized semi-natural environments (ponds), and one year later offspring (F1, N = 652) were presented with repeated behavioural assays. Individuals were challenged to reach a food source through a novel transparent obstacle, during which exploration, activity, foraging, sociability and wall-biting behaviours were recorded through video observation. We found that coping responses of individuals from the first generation to this unfamiliar foraging challenge were related to even relatively small, naturally diversified variation in developmental environment. All measured behaviours were correlated with each other. Especially exploration, sociability and wall-biting were found to differ significantly between ponds. These differences could not be explained by stickleback density or the turbidity of the water. Findings Our findings show that a) differences in early-life environment appear to affect stickleback feeding behaviour later in life; b) this is the case even when the environmental differences are only small, within natural parameters and diversified gradually; and c) effects are present despite semi-natural conditions that fluctuate during the year. Therefore, in behaviourally plastic animals like the stickleback, the adaptive response to human

  4. Oral nutritional supplements containing (n-3) polyunsaturated fatty acids affect the nutritional status of patients with stage III non-small cell lung cancer during multimodality treatment.

    PubMed

    van der Meij, Barbara S; Langius, Jacqueline A E; Smit, Egbert F; Spreeuwenberg, Marieke D; von Blomberg, B Mary E; Heijboer, Annemieke C; Paul, Marinus A; van Leeuwen, Paul A M

    2010-10-01

    Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), (n-3) fatty acids from fish oil, have immune-modulating effects and may improve nutritional status in cancer. The objective of this study was to investigate the effects of an oral nutritional supplement containing (n-3) fatty acids on nutritional status and inflammatory markers in patients with non-small cell lung cancer (NSCLC) undergoing multimodality treatment. In a double-blind experiment, 40 patients with stage III NSCLC were randomly assigned to receive 2 cans/d of a protein- and energy-dense oral nutritional supplement containing (n-3) fatty acids (2.0 g EPA + 0.9 g DHA/d) or an isocaloric control supplement. EPA in plasma phospholipids, energy intake, resting energy expenditure (REE), body weight, fat free mass (FFM), mid-upper arm circumference (MUAC), and inflammatory markers were assessed. Effects of intervention were analyzed by generalized estimating equations and expressed as regression coefficients (B). The intervention group (I) had a better weight maintenance than the control (C) group after 2 and 4 wk (B = 1.3 and 1.7 kg, respectively; P < 0.05), a better FFM maintenance after 3 and 5 wk (B = 1.5 and 1.9 kg, respectively; P < 0.05), a reduced REE (B = -16.7% of predicted; P = 0.01) after 3 wk, and a trend for a greater MUAC (B = 9.1; P = 0.06) and lower interleukin-6 production (B = -27.9; P = 0.08) after 5 wk. After 4 wk, the I group had a higher energy and protein intake than the C group (B = 2456 kJ/24 h, P = 0.03 and B = 25.0 g, P = 0.01, respectively). In conclusion, a protein- and energy-dense oral nutritional supplement containing (n-3) fatty acids beneficially affects nutritional status during multimodality treatment in patients with NSCLC.

  5. Factors affecting the occurrence of saugers in small, high-elevation rivers near the western edge of the species' natural distribution

    USGS Publications Warehouse

    Amadio, C.J.; Hubert, W.A.; Johnson, K.; Oberlie, D.; Dufek, D.

    2005-01-01

    Factors affecting the occurrence of saugers Sander canadensis were studied throughout the Wind River basin, a high-elevation watershed (> 1,440 m above mean sea level) on the western periphery of the species' natural distribution in central Wyoming. Adult saugers appeared to have a contiguous distribution over 170 km of streams among four rivers in the watershed. The upstream boundaries of sauger distribution were influenced by summer water temperatures and channel slopes in two rivers and by water diversion dams that created barriers to upstream movement in the other two rivers. Models that included summer water temperature, maximum water depth, habitat type (pool or run), dominant substrate, and alkalinity accounted for the variation in sauger occurrence across the watershed within the areas of sauger distribution. Water temperature was the most important basin-scale habitat feature associated with sauger occurrence, and maximum depth was the most important site-specific habitat feature. Saugers were found in a larger proportion of pools than runs in all segments of the watershed and occurred almost exclusively in pools in upstream segments of the watershed. Suitable summer water temperatures and deep, low-velocity habitat were available to support saugers over a large portion of the Wind River watershed. Future management of saugers in the Wind River watershed, as well as in other small river systems within the species' native range, should involve (1) preserving natural fluvial processes to maintain the summer water temperatures and physical habitat features needed by saugers and (2) assuring that barriers to movement do not reduce upstream boundaries of populations.

  6. Different dietary energy intake affects skeletal muscle development through an Akt-dependent pathway in Dorper × Small Thin-Tailed crossbred ewe lambs.

    PubMed

    Zhao, J X; Liu, X D; Li, K; Liu, W Z; Ren, Y S; Zhang, J X

    2016-10-01

    The objective of this experiment was to investigate the mechanisms through which different levels of dietary energy affect postnatal skeletal muscle development in ewe lambs. Twelve Dorper × Small Thin-Tailed crossbred ewe lambs (100 d of age; 20 ± 0.5 kg BW) were selected randomly and divided into 2 groups in a completely randomized design. Animals were offered identical diets at 100% or 65% of ad libitum intake. Lambs were euthanized when BW in the ad libitum group reached 35 kg and the semitendinosus muscle was sampled. Final BW and skeletal muscle weight were decreased (P < 0.01) by feed restriction. Both muscle fiber size distribution and myofibril cross-sectional area were altered by feed restriction. Insulin-like growth factor 1 (IGF-1) messenger RNA (mRNA) content was decreased (P < 0.05) when lambs were underfed, whereas no difference for IGF-2 mRNA expression was observed (P > 0.05). Feed restriction altered phosphor-Akt protein abundance (P < 0.01). Moreover, the mammalian target of rapamycin (mTOR) pathway was inhibited by feed restriction, which was associated with decreased phosphor-mTOR, phosphorylated eukaryotic initiation factor 4E binding protein 1 (phosphor-4EBP1), and phosphorylated ribosomal protein S6 kinase (phosphor-S6K). Both mRNA expression of myostatin and its protein content were elevated in feed-restricted ewe lambs (P < 0.05). In addition, mRNA expression of both muscle RING finger 1 and muscle atrophy F-box was increased when ewe lambs were underfed. In summary, feed restriction in young growing ewe lambs attenuates skeletal muscle hypertrophy by inhibiting protein synthesis and increasing protein degradation, which may act through the Akt-dependent pathway.

  7. Is Small Business Doomed?

    ERIC Educational Resources Information Center

    Business Education Forum, 1979

    1979-01-01

    Provides a sampling of viewpoints from businessmen, economists, futurists, and government experts on the future of small business presented at hearings before the Subcommittee on Antitrust, Consumers, and Employment, Committee on Small Business, House of Representatives. Problems of taxes, the economy, and government regulations are discussed from…

  8. Small intestine (image)

    MedlinePlus

    The small intestine is the portion of the digestive system most responsible for absorption of nutrients from food into the bloodstream. The pyloric sphincter governs the passage of partly digested food ...

  9. What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs.

    PubMed

    Kang, Kyung-Nam; Lee, Yoon-Sik

    2008-10-01

    Research-intensive small and medium-sized enterprises (SMEs) play a crucial role in the advancement of the biotechnology industry. This paper explored the impacts of internal and contextual variables on innovative activity in Korea and compared the results of this analysis with previous studies of other countries. Our analysis of 149 Korean biotech SMEs showed that the ratio of R&D expenditure to sales, the ratio of R&D employees to total employees, CEO characteristics, governmental support and international networking are positively correlated with a firm's innovation performance. The results may help decision makers to better foster SMEs in the Korean biotechnology industry.

  10. Outpatient Management of Postbiopsy Pneumothorax with Small-Caliber Chest Tubes: Factors Affecting the Need for Prolonged Drainage and Additional Interventions

    SciTech Connect

    Gupta, Sanjay Hicks, Marshall E.; Wallace, Michael J.; Ahrar, Kamran; Madoff, David C.; Murthy, Ravi

    2008-03-15

    The aim of this study was to evaluate the efficacy of outpatient management of postbiopsy pneumothoraces with small-caliber chest tubes and to assess the factors that influence the need for prolonged drainage or additional interventions.We evaluated the medical records of patients who were treated with small-caliber chest tubes attached to Heimlich valves for pneumothoraces resulting from image-guided transthoracic needle biopsy to determine the hospital admission rates, the number of days the catheters were left in place, and the need for further interventions. We also evaluated the patient, lesion, and biopsy technique characteristics to determine their influence on the need for prolonged catheter drainage or additional interventions. Of the 191 patients included in our study, 178 (93.2%) were treated as outpatients. Ten patients (5.2%) were admitted for chest tube-related problems, either for underwater suction (n = 8) or for pain control (n = 2). No further interventions were required in 146 patients (76.4%), with successful removal of the chest tubes the day after the biopsy procedure. Prolonged catheter drainage (mean, 4.3 days) was required in 44 patients (23%). Nineteen patients (9.9%) underwent additional interventions for management of pneumothorax. Presence of emphysema was noted more frequently in patients who required additional interventions or prolonged chest tube drainage than in those who did not (51.1% vs. 24.7%; p = 0.001).We conclude that use of the Heimlich valve allows safe and successful outpatient treatment of most patients requiring chest tube placement for postbiopsy pneumothorax. Additional interventions or prolonged chest tube drainage are needed more frequently in patients with emphysema in the needle path.

  11. Small-scale patterns in snowmelt timing affect gene flow and the distribution of genetic diversity in the alpine dwarf shrub Salix herbacea.

    PubMed

    Cortés, A J; Waeber, S; Lexer, C; Sedlacek, J; Wheeler, J A; van Kleunen, M; Bossdorf, O; Hoch, G; Rixen, C; Wipf, S; Karrenberg, S

    2014-09-01

    Current threats to biodiversity, such as climate change, are thought to alter the within-species genetic diversity among microhabitats in highly heterogeneous alpine environments. Assessing the spatial organization and dynamics of genetic diversity within species can help to predict the responses of organisms to environmental change. In this study, we evaluated whether small-scale heterogeneity in snowmelt timing restricts gene flow between microhabitats in the common long-lived dwarf shrub Salix herbacea L. We surveyed 273 genets across 12 early- and late-snowmelt sites (that is, ridges and snowbeds) in the Swiss Alps for phenological variation over 2 years and for genetic variation using seven SSR markers. Phenological differentiation triggered by differences in snowmelt timing did not correlate with genetic differentiation between microhabitats. On the contrary, extensive gene flow appeared to occur between microhabitats and slightly less extensively among adjacent mountains. However, ridges exhibited significantly lower levels of genetic diversity than snowbeds, and patterns of effective population size (Ne) and migration (Nem) between microhabitats were strongly asymmetric, with ridges acting as sources and snowbeds as sinks. As no recent genetic bottlenecks were detected in the studied sites, this asymmetry is likely to reflect current meta-population dynamics of the species dominated by gene flow via seeds rather than ancient re-colonization after the last glacial period. Overall, our results suggest that seed dispersal prevents snowmelt-driven genetic isolation, and snowbeds act as sinks of genetic diversity. We discuss the consequences of such small-scale variation in gene flow and diversity levels for population responses to climate change.

  12. How does Australia's largest dolphin-watching industry affect the behaviour of a small and resident population of Indo-Pacific bottlenose dolphins?

    PubMed

    Steckenreuter, Andre; Möller, Luciana; Harcourt, Robert

    2012-04-30

    The small, genetically distinct population of Indo-Pacific bottlenose dolphins (Tursiops aduncus) in Port Stephens, New South Wales (NSW), is the target of the largest dolphin-watching industry in Australia and is located within the Port Stephens - Great Lakes Marine Park that was created in 2005. The effects of this industry have been identified as of significant management importance by the Marine Parks Authority NSW. Accordingly, the impact of commercial dolphin-watching boats was investigated from boat-based surveys from August 2008 to August 2009. Presence of dolphin-watching boats altered both the dolphins' behavioural states and activity budgets. Dolphins spent 66.5% less time feeding and 44.2% less time socialising, spent four times more milling, and were never observed to rest in the presence of dolphin-watching boats. Moreover, dolphin groups were more cohesive during dolphin-watching boat encounters and dolphins tended to avoid tour boats. These effects were exacerbated as the number of boats increased and the distance from boats decreased. The rate of approach was high with boats approaching each dolphin group three times per day in winter and six times in summer. Moreover, groups of dolphins with newborns were approached closer than state regulated minimum approach distances in nine out of ten encounters. Globally, dolphin-watching industries frequent small resident groups of coastal dolphins and effects are likely to be similar. We suggest that existing controls are inadequate and that these together with additional regulations be enforced by a regular presence of authorities. We suggest no more than one dolphin-watching boat within 50 m of a group of dolphins, or 100 m if calves are present. Operating times of dolphin-watching boats should be restricted in numbers after 1 pm, i.e., during preferred foraging times for dolphins. Additionally, exclusion zones should be considered to reduce pressure on dolphins undertaking critical activities such as

  13. How does Australia's largest dolphin-watching industry affect the behaviour of a small and resident population of Indo-Pacific bottlenose dolphins?

    PubMed

    Steckenreuter, Andre; Möller, Luciana; Harcourt, Robert

    2012-04-30

    The small, genetically distinct population of Indo-Pacific bottlenose dolphins (Tursiops aduncus) in Port Stephens, New South Wales (NSW), is the target of the largest dolphin-watching industry in Australia and is located within the Port Stephens - Great Lakes Marine Park that was created in 2005. The effects of this industry have been identified as of significant management importance by the Marine Parks Authority NSW. Accordingly, the impact of commercial dolphin-watching boats was investigated from boat-based surveys from August 2008 to August 2009. Presence of dolphin-watching boats altered both the dolphins' behavioural states and activity budgets. Dolphins spent 66.5% less time feeding and 44.2% less time socialising, spent four times more milling, and were never observed to rest in the presence of dolphin-watching boats. Moreover, dolphin groups were more cohesive during dolphin-watching boat encounters and dolphins tended to avoid tour boats. These effects were exacerbated as the number of boats increased and the distance from boats decreased. The rate of approach was high with boats approaching each dolphin group three times per day in winter and six times in summer. Moreover, groups of dolphins with newborns were approached closer than state regulated minimum approach distances in nine out of ten encounters. Globally, dolphin-watching industries frequent small resident groups of coastal dolphins and effects are likely to be similar. We suggest that existing controls are inadequate and that these together with additional regulations be enforced by a regular presence of authorities. We suggest no more than one dolphin-watching boat within 50 m of a group of dolphins, or 100 m if calves are present. Operating times of dolphin-watching boats should be restricted in numbers after 1 pm, i.e., during preferred foraging times for dolphins. Additionally, exclusion zones should be considered to reduce pressure on dolphins undertaking critical activities such as

  14. Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer.

    PubMed

    Kreisler, A; Strissel, P L; Strick, R; Neumann, S B; Schumacher, U; Becker, C-M

    2010-10-28

    The neuron-restrictive silencer factor/RE1-silencing transcription factor (NRSF/REST) is a negative regulator of gene expression restricting the expression of neuronal genes to the nervous system. NRSF/REST is highly expressed in non-neuronal tissues like the lung. In previous work, we identified small-cell lung cancer (SCLC) cell lines with no detectable NRSF/REST expression that, as a consequence, expressed neuronal markers like L1-cell adhesion molecule (L1-CAM) and neural cell adhesion molecule (NCAM). The loss of NRSF/REST expression was linked to malignant progression; however, its mechanistic role remained elusive. Here, we show that NRSF/REST itself, rather than one of its regulated genes, acts like a classic tumour suppressor, being in part regulated by methylation. In SCLCs, NRSF/REST is positively regulated by CREB, with an NRSF/REST promoter fragment showing cell type specificity. Downstream, NRSF/REST directly regulates AKT2, in which NRSF/REST loss leads to an epidermal growth factor-mediated de-regulation of AKT-Serine473 phosphorylation, important for cellular proliferation and survival. Assaying anchorage-independent growth, we observed that with reduced NRSF/REST expression, proliferation was significantly enhanced, whereas NRSF/REST rescue decreased the potential of cells to grow anchorage independently. Our observations support the fact that NRSF/REST may act as an important modulator of malignant progression in SCLC. PMID:20697351

  15. The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells.

    PubMed

    Amornwichet, Napapat; Oike, Takahiro; Shibata, Atsushi; Nirodi, Chaitanya S; Ogiwara, Hideaki; Makino, Haruhiko; Kimura, Yuka; Hirota, Yuka; Isono, Mayu; Yoshida, Yukari; Ohno, Tatsuya; Kohno, Takashi; Nakano, Takashi

    2015-06-11

    Carbon-ion radiotherapy (CIRT) holds promise to treat inoperable locally-advanced non-small cell lung carcinoma (NSCLC), a disease poorly controlled by standard chemoradiotherapy using X-rays. Since CIRT is an extremely limited medical resource, selection of NSCLC patients likely to benefit from it is important; however, biological predictors of response to CIRT are ill-defined. The present study investigated the association between the mutational status of EGFR and KRAS, driver genes frequently mutated in NSCLC, and the relative biological effectiveness (RBE) of carbon-ion beams over X-rays. The assessment of 15 NSCLC lines of different EGFR/KRAS mutational status and that of isogenic NSCLC lines expressing wild-type or mutant EGFR revealed that EGFR-mutant NSCLC cells, but not KRAS-mutant cells, show low RBE. This was attributable to (i) the high X-ray sensitivity of EGFR-mutant cells, since EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA double-strand break (DSB) repair, and (ii) the strong cell-killing effect of carbon-ion beams due to poor repair of carbon-ion beam-induced DSBs regardless of EGFR mutation status. These data highlight the potential of EGFR mutation status as a predictor of response to CIRT, i.e., CIRT may show a high therapeutic index in EGFR mutation-negative NSCLC.

  16. Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets.

    PubMed

    Wang, Xiaoqiu; Yang, Fang; Liu, Chuang; Zhou, Huaijun; Wu, Guoyao; Qiao, Shiyan; Li, Defa; Wang, Junjun

    2012-01-01

    Antibiotics have long been used in animal production and medication to alleviate weaning stress. However, due to the concerns over food safety and human health, its use in animal production has been prohibited in many countries. Therefore, there is growing interest in developing alternative additives, such as a probiotic Lactobacillus. In this study, a proteomic approach coupled with biochemical analysis was applied to investigate alterations of proteomes in the small intestinal mucosa of weanling piglets after a 13-d period of feeding with supplemental L. fermentum I5007 or aureomycin (an antibiotic). We indentified 27 differentially expressed protein spots that participated in 7 key biological processes, including: 1) energy metabolism; 2) lipid metabolism; 3) protein synthesis; 4) cell structure and mobility; 5) cellular proliferation and apoptosis; 6) immune response; and 7) stress response and detoxification. Both L. fermentum I5007 and aureomycin decreased the expression of proteins related to apoptosis, stress response, and increased the expression of proteins related to detoxification in the gastrointestinal (GI) tract of weanling piglets. L. fermentum I5007 exhibited additional effects in alleviating weaning stress syndrome by enhancing the levels of proteins involved in energy metabolism, lipid metabolism, cell structure and mobility, protein synthesis, and immune response, thereby facilitating cellular proliferation and depressing apoptosis. In contrast, aureomycin reduced the levels of proteins related to energy metabolism, protein synthesis, cell structure, motility, and immunity. These novel findings have important implications for understanding the mechanisms whereby L. fermentum I5007 can improve the GI health of postweaning piglets. PMID:22113866

  17. The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells.

    PubMed

    Amornwichet, Napapat; Oike, Takahiro; Shibata, Atsushi; Nirodi, Chaitanya S; Ogiwara, Hideaki; Makino, Haruhiko; Kimura, Yuka; Hirota, Yuka; Isono, Mayu; Yoshida, Yukari; Ohno, Tatsuya; Kohno, Takashi; Nakano, Takashi

    2015-01-01

    Carbon-ion radiotherapy (CIRT) holds promise to treat inoperable locally-advanced non-small cell lung carcinoma (NSCLC), a disease poorly controlled by standard chemoradiotherapy using X-rays. Since CIRT is an extremely limited medical resource, selection of NSCLC patients likely to benefit from it is important; however, biological predictors of response to CIRT are ill-defined. The present study investigated the association between the mutational status of EGFR and KRAS, driver genes frequently mutated in NSCLC, and the relative biological effectiveness (RBE) of carbon-ion beams over X-rays. The assessment of 15 NSCLC lines of different EGFR/KRAS mutational status and that of isogenic NSCLC lines expressing wild-type or mutant EGFR revealed that EGFR-mutant NSCLC cells, but not KRAS-mutant cells, show low RBE. This was attributable to (i) the high X-ray sensitivity of EGFR-mutant cells, since EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA double-strand break (DSB) repair, and (ii) the strong cell-killing effect of carbon-ion beams due to poor repair of carbon-ion beam-induced DSBs regardless of EGFR mutation status. These data highlight the potential of EGFR mutation status as a predictor of response to CIRT, i.e., CIRT may show a high therapeutic index in EGFR mutation-negative NSCLC. PMID:26065573

  18. Lipid, detergent, and Coomassie Blue G-250 affect the migration of small membrane proteins in blue native gels: mitochondrial carriers migrate as monomers not dimers.

    PubMed

    Crichton, Paul G; Harding, Marilyn; Ruprecht, Jonathan J; Lee, Yang; Kunji, Edmund R S

    2013-07-26

    Blue native gel electrophoresis is a popular method for the determination of the oligomeric state of membrane proteins. Studies using this technique have reported that mitochondrial carriers are dimeric (composed of two ∼32-kDa monomers) and, in some cases, can form physiologically relevant associations with other proteins. Here, we have scrutinized the behavior of the yeast mitochondrial ADP/ATP carrier AAC3 in blue native gels. We find that the apparent mass of AAC3 varies in a detergent- and lipid-dependent manner (from ∼60 to ∼130 kDa) that is not related to changes in the oligomeric state of the protein, but reflects differences in the associated detergent-lipid micelle and Coomassie Blue G-250 used in this technique. Higher oligomeric state species are only observed under less favorable solubilization conditions, consistent with aggregation of the protein. Calibration with an artificial covalent AAC3 dimer indicates that the mass observed for solubilized AAC3 and other mitochondrial carriers corresponds to a monomer. Size exclusion chromatography of purified AAC3 in dodecyl maltoside under blue native gel-like conditions shows that the mass of the monomer is ∼120 kDa, but appears smaller on gels (∼60 kDa) due to the unusually high amount of bound negatively charged dye, which increases the electrophoretic mobility of the protein-detergent-dye micelle complex. Our results show that bound lipid, detergent, and Coomassie stain alter the behavior of mitochondrial carriers on gels, which is likely to be true for other small membrane proteins where the associated lipid-detergent micelle is large when compared with the mass of the protein.

  19. P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

    PubMed Central

    Zhang, E-b; Yin, D-d; Sun, M; Kong, R; Liu, X-h; You, L-h; Han, L; Xia, R; Wang, K-m; Yang, J-s; De, W; Shu, Y-q; Wang, Z-x

    2014-01-01

    Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified at a rapid pace. These RNAs have critical roles in diverse biological processes, including tumorigenesis. Here we report that taurine-upregulated gene 1 (TUG1), a 7.1-kb lncRNA, recruiting and binding to polycomb repressive complex 2 (PRC2), is generally downregulated in non-small cell lung carcinoma (NSCLC) tissues. In a cohort of 192 NSCLC patients, the lower expression of TUG1 was associated with a higher TNM stage and tumor size, as well as poorer overall survival (P<0.001). Univariate and multivariate analyses revealed that TUG1 expression serves as an independent predictor for overall survival (P<0.001). Further experiments revealed that TUG1 expression was induced by p53, and luciferase and chromatin immunoprecipitation (ChIP) assays confirmed that TUG1 was a direct transcriptional target of p53. TUG1 knockdown significantly promoted the proliferation in vitro and in vivo. Moreover, the lncRNA-mediated regulation of the expression of HOX genes in tumorigenesis and development has been recently receiving increased attention. Interestingly, inhibition of TUG1 could upregulate homeobox B7 (HOXB7) expression; ChIP assays demonstrated that the promoter of HOXB7 locus was bound by EZH2 (enhancer of zeste homolog 2), a key component of PRC2, and was H3K27 trimethylated. This TUG1-mediated growth regulation is in part due to specific modulation of HOXB7, thus participating in AKT and MAPK pathways. Together, these results suggest that p53-regulated TUG1 is a growth regulator, which acts in part through control of HOXB7. The p53/TUG1/PRC2/HOXB7 interaction might serve as targets for NSCLC diagnosis and therapy. PMID:24853421

  20. Does immunohistochemistry affect response to therapy and survival of inoperable non-small cell lung carcinoma patients? A survey of 145 stage III-IV consecutive cases.

    PubMed

    Pelosi, Giuseppe; Haspinger, Eva Regina; Bimbatti, Manuela; Leone, Giorgia; Paolini, Biagio; Fabbri, Alessandra; Tamborini, Elena; Perrone, Federica; Testi, Adele; Garassino, Marina; Maisonneuve, Patrick; de Braud, Filippo; Pilotti, Silvana; Pastorino, Ugo

    2014-04-01

    Whether non-small cell lung carcinoma (NSCLC) unveiled by immunohistochemistry (IHC) has the same clinical outcome as those typed by morphology is still matter of debate. A total of 145 stage III-IV, consecutive inoperable NSCLC patients treated by chemotherapy (133 cases) or EGFR tyrosine kinase inhibitor (12 cases) and including 100 biopsies, 11 surgical specimens, and 34 cytological samples had originally accounted for 120 adenocarcinomas (ADs), 19 squamous cell carcinomas (SQCs), and 6 adenosquamous carcinomas (ADSQCs) by integrating morphology and thyroid transcription factor-1 (TTF1)/p40 IHC. Thirty-two NSCLC-not otherwise specified (NSCLC-NOS) cases were identified by morphology revision of the original diagnoses, which showed solid growth pattern (P < .001), 22 ADs, 5 SQCs, and 5 ADSQCs by IHC profiling (P < .001), and 10 gene-altered tumors (3 EGFR, 5 KRAS, and 2 ALK). While no significant relationships were observed between response to therapy and original, morphology or IHC diagnoses, driver mutations and tumor differentiation by TTF1 expression, AD run better progression-free survival (PFS) or overall survival (OS) than other tumor types by morphology (P = .010 and P = .047) and IHC (P = .033 and P = .046), respectively. Furthermore, patients with NSCLC-NOS confirmed as AD by IHC tended to have poorer OS (P = .179) and PFS (P = .193) similar to that of ADSQC and SQC (P = .702 and P = .540, respectively). A category of less differentiated AD with poorer prognosis on therapy could be identified by IHC, while there were no differences for SQC or ADSQC. The terminology of "NSCLC-NOS, favor by IHC" is appropriate to alert clinicians toward more aggressive tumors. PMID:24326823

  1. Local and national trends in general surgery residents' operative experience: do work hour limitations negatively affect case volume in small community-based programs?

    PubMed

    Markelov, Alexey; Sakharpe, Aniket; Kohli, Harjeet; Livert, David

    2011-12-01

    The goals of this study were to analyze the impact of work hour restrictions on the operative case volume at a small community-based general surgery residency training program and compare changes with the national level. Annual national resident case log data from Accreditation Council for Graduate Medical Education (ACGME) website and case logs of graduating Easton Hospital residents (years 2002-2009) were used for analysis. Weighted average change in total number of cases in our institution was -1.20 (P = 0.52) vs 1.78 (P = 0.07) for the national program average with statistically significant difference on comparison (P = 0.027). We also found significant difference in case volume changes at the national level compared with our institution for the following ACGME defined subcategories: alimentary tract [8.19 (P < 0.01) vs -1.08 (P = 0.54)], abdomen [8.48 (P < 0.01) vs -6.29 (P < 0.01)], breast [1.91 (P = 0.89) vs -3.6 (P = 0.02)], and vascular [4.03 (P = 0.02) vs -3.98 (P = 0.01)]. Comparing the national trend to the community hospital we see that there is total increase in cases at the national level whereas there is a decrease in case volume at the community hospital. These trends can also be followed in ACGME defined subcategories which form the major case load for a general surgical training such as alimentary tract, abdominal, breast, and vascular procedures. We hypothesize that work hour restrictions have been favorable for the larger programs, as these programs were able to better integrate the night float system, restructure their call schedule, and implement institutional modifications which are too resource demanding for smaller training programs.

  2. When can preheating affect the CMB?

    NASA Astrophysics Data System (ADS)

    Tsujikawa, Shinji; Bassett, Bruce A.

    2002-05-01

    We discuss the principles governing the selection of inflationary models for which preheating can affect the CMB. This is a (fairly small) subset of those models which have nonnegligible entropy/isocurvature perturbations on large scales during inflation. We study new models which belong to this class-two-field inflation with negative nonminimal coupling and hybrid/double/supernatural inflation models where the tachyonic growth of entropy perturbations can lead to the variation of the curvature perturbation, /R, on super-Hubble scales. Finally, we present evidence against recent claims for the variation of /R in the absence of substantial super-Hubble entropy perturbations.

  3. A Plan for Individualizing Instruction for the Senior Government Class Through Use of Problem Solving Units. Colorado Western States Small Schools Project Documentation (Silverton High School, Silverton, Colorado, 1963-64).

    ERIC Educational Resources Information Center

    Higgs, Norman E.

    During the 1963-64 school year, a secondary teacher from the rurally isolated area of Silverton, Colorado initiated an individualized program in problem solving for a senior social studies class (N=8-10). Utilizing community resources, the instructor planned several units on government, while the students selected resource materials from the…

  4. Small satellites

    NASA Technical Reports Server (NTRS)

    Thomas, P.; Veverka, J.; Dermott, S.

    1986-01-01

    Satellites smaller than Mimas (r = 195 km) are distinguished by irregular overall shapes and by rough limb topography. Material properties and impact cratering dominate the shaping of these objects. Long fragmentation histories can produce a variety of internal structures, but so far there is no direct evidence that any small satellite is an equilibrium ellipsoid made up of noncohesive gravitationally bound rubble. One many bodies that orbit close to their primary the tidal and rotational components of surface gravity strongly affect the directions of local g and thereby affect the redistribution of regolith by mass wasting. Downslope movement of regolith is extensive on Deimos, and is probably effective on many other small satellites. It is shown that in some cases observed patterns of downslope mass wasting cold produce useful constraints on the satellite's mean density. The diversity of features seen in the few high-resolution images of small satellites currently available suggests that these objects have undergone complex histories of cratering, fragmentation, and regolith evolution.

  5. Leisure, Government and Governance: A Swedish Perspective

    ERIC Educational Resources Information Center

    Lindstrom, Lisbeth

    2011-01-01

    The leisure sector has witnessed a tremendous expansion since 1960. The purpose of this article is to analyse the decisions and goals of Swedish government policy during the period 1962 to 2005. The empirical analysis covers government Propositions and governmental investigations. The fields covered are sports, culture, exercise, tourism and…

  6. Wyoming Government, Unit VII.

    ERIC Educational Resources Information Center

    Robinson, Terry

    This unit on Wyoming government presents concepts, activities, and stories for elementary school students. Concepts stress that the functions of government are determined according to the demands, needs, and traditions of the people; each part of government has a special function; as citizens, we should be loyal to the underlying concepts of our…

  7. Taking Student Government Seriously.

    ERIC Educational Resources Information Center

    Bolen, J. R.

    1999-01-01

    Discusses the student government at La Mesa Middle School (California) that was modeled after the three-branch U.S. government as a means for increasing students' civic understanding. Describes the structure of the legislative, judicial, and executive branches, the different activities of the student government, and the reasons for the hiatus.…

  8. Modelling University Governance

    ERIC Educational Resources Information Center

    Trakman, Leon

    2008-01-01

    Twentieth century governance models used in public universities are subject to increasing doubt across the English-speaking world. Governments question if public universities are being efficiently governed; if their boards of trustees are adequately fulfilling their trust obligations towards multiple stakeholders; and if collegial models of…

  9. Governance in Strategic Context

    ERIC Educational Resources Information Center

    Alfred, Richard L.

    2008-01-01

    This chapter begins with a retrospective look at governance in community colleges based on a working understanding of governance as a correlate of decision making. In its simplest form, governance is "a process for distributing authority, power, and influence in decision making among constituencies" (Alfred and Smydra, 1985, pp. 201-202). What…

  10. Teaching about Comparative Government

    ERIC Educational Resources Information Center

    Risinger, C. Frederick

    2009-01-01

    As international relationships become increasingly important (with both friendly and not-so-friendly governments), the author believes that it is important for U.S. students to learn about how a parliamentary democracy works--how it is similar, but different from a presidential-style government. Learning about the systems of government of other…

  11. Government Approaches to Foster Competitive Intelligence Practice in SMEs: A Comparative Study of Eight Governments.

    ERIC Educational Resources Information Center

    Bergeron, Pierrette

    2000-01-01

    Presents results from a study examining approaches developed by seven governments to foster competitive intelligence practice in SMEs (small and medium enterprises) and compares them with the approach taken by the government of Quebec. Suggests a need for a better understanding of information needs and uses in SMEs. (Contains 22 references.)…

  12. 77 FR 325 - Proposed Information Collection (Certification of Change or Correction of Name, Government Life...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... information technology. Title: Certification of Change or Correction of Name, Government Life Insurance, VA... Government Life Insurance policies. Affected Public: Individuals or households. Estimated Annual Burden: 20... AFFAIRS Proposed Information Collection (Certification of Change or Correction of Name, Government...

  13. Economic Choices. Political Decisions that Affect You.

    ERIC Educational Resources Information Center

    Fritsche, Joellen M.; And Others

    The purpose of this book is to help students understand why the U.S. Government is involved in the economy, the underlying social values that government tries to promote, and how U.S. economic decisions affect the global economy. It was designed to give them the background they need to form their own opinions about the role of government in the…

  14. 13 CFR 125.4 - Government property sales assistance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Government property sales assistance. 125.4 Section 125.4 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.4 Government property sales assistance. (a) The purpose of SBA's...

  15. 13 CFR 125.4 - Government property sales assistance.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Government property sales assistance. 125.4 Section 125.4 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.4 Government property sales assistance. (a) The purpose of SBA's...

  16. 13 CFR 125.4 - Government property sales assistance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Government property sales assistance. 125.4 Section 125.4 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.4 Government property sales assistance. (a) The purpose of SBA's...

  17. 13 CFR 125.4 - Government property sales assistance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Government property sales assistance. 125.4 Section 125.4 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.4 Government property sales assistance. (a) The purpose of SBA's...

  18. 75 FR 66411 - Small Entity Compliance Guide: Women-Owned Small Business Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... Government Contracting, U.S. Small Business Administration, 409 Third Street, SW., Washington, DC 20416. For... 21, 2010. Karen Hontz, Director, Office of Government Contracting. BILLING CODE 8025-01-P ... From the Federal Register Online via the Government Publishing Office SMALL...

  19. 78 FR 30384 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ..., Procurement Analyst, Small Business Administration, Office ] of Government Contracting, 409 3rd Street SW..., Director, Office of Government Contracting. BILLING CODE 8025-01-P ... From the Federal Register Online via the Government Publishing Office SMALL...

  20. 48 CFR 2919.202-2 - Locating small business sources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... small business sources. Any procurement conducted on an unrestricted basis will include solicitations to small businesses of each category with legislatively established government-wide procurement goals...

  1. 7 CFR 1717.1208 - Government's rights under loan documents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Government's rights under loan documents. 1717.1208... ELECTRIC LOANS Settlement of Debt § 1717.1208 Government's rights under loan documents. Nothing in this subpart limits, modifies, or otherwise affects the rights of the government under loan documents...

  2. 7 CFR 1717.1208 - Government's rights under loan documents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Government's rights under loan documents. 1717.1208... ELECTRIC LOANS Settlement of Debt § 1717.1208 Government's rights under loan documents. Nothing in this subpart limits, modifies, or otherwise affects the rights of the government under loan documents...

  3. 7 CFR 1717.1208 - Government's rights under loan documents.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 11 2011-01-01 2011-01-01 false Government's rights under loan documents. 1717.1208... ELECTRIC LOANS Settlement of Debt § 1717.1208 Government's rights under loan documents. Nothing in this subpart limits, modifies, or otherwise affects the rights of the government under loan documents...

  4. 7 CFR 1717.1208 - Government's rights under loan documents.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 11 2012-01-01 2012-01-01 false Government's rights under loan documents. 1717.1208... ELECTRIC LOANS Settlement of Debt § 1717.1208 Government's rights under loan documents. Nothing in this subpart limits, modifies, or otherwise affects the rights of the government under loan documents...

  5. 7 CFR 1717.1208 - Government's rights under loan documents.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Government's rights under loan documents. 1717.1208... ELECTRIC LOANS Settlement of Debt § 1717.1208 Government's rights under loan documents. Nothing in this subpart limits, modifies, or otherwise affects the rights of the government under loan documents...

  6. The American Economy: Government's Role, Citizen's Choice. [Student Text and] Teacher's Guide. Third Edition.

    ERIC Educational Resources Information Center

    Sass, Charles R., Ed.

    This student text and teacher's guide examine the government's role in the U.S. economy and how the choices made by the government affect each citizen. The following topics are addressed: (1) why government gets involved in the economy and the social and economic goals the government tries to achieve; (2) how government monetary, fiscal, and trade…

  7. 77 FR 18258 - Government-to-Government Telephonic Consultation Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR National Park Service Government-to-Government Telephonic Consultation Meetings AGENCY: National Park Service, Interior. SUMMARY: The National Park Service announces two telephonic government-...

  8. How nurse leaders can foster a climate of good governance.

    PubMed

    Bassett, Sally; Westmore, Kathryn

    2012-09-01

    This article is the first in a series of four examining the components of good corporate governance. Poor governance can result in patients receiving poor quality care; all healthcare professionals, therefore, have a role in ensuring effective governance. This article discusses how an organisation's culture and leadership can contribute to good corporate governance. Nurse leaders can influence the culture of effective governance by building trust and respect and challenging the behaviours that led to poor quality care. The next article in this series will look at how an organisation's systems and processes can affect the effectiveness of its governance. PMID:23008901

  9. How nurse leaders can foster a climate of good governance.

    PubMed

    Bassett, Sally; Westmore, Kathryn

    2012-09-01

    This article is the first in a series of four examining the components of good corporate governance. Poor governance can result in patients receiving poor quality care; all healthcare professionals, therefore, have a role in ensuring effective governance. This article discusses how an organisation's culture and leadership can contribute to good corporate governance. Nurse leaders can influence the culture of effective governance by building trust and respect and challenging the behaviours that led to poor quality care. The next article in this series will look at how an organisation's systems and processes can affect the effectiveness of its governance.

  10. The Iraqi Governing Council

    ERIC Educational Resources Information Center

    Social Education, 2004

    2004-01-01

    This article provides the details of the chronological events surrounding the establishment of a Governing Council in Iraq in July 2003 by the United States, acting as the leader of the Coalition Provisional Authority (CPA) that administers Iraq. The following topics are discussed in the article: (1) The Composition of the Governing Council; (2)…

  11. Government Quality Conference Proceedings

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Government Quality Conference was an attempt to bring together executive organizations and senior individuals in the Federal Government that have a desire to improve productivity. It was designed to provide an exchange of ideas based on experience, and to encourage individual management initiatives to tap the capabilities of Federal employees.

  12. Restructuring for Good Governance

    ERIC Educational Resources Information Center

    Robert, Stephen; Carey, Russell C.

    2006-01-01

    American higher education has never been more in need of good governance than it is right now. Yet much of the structure many boards have inherited or created tends to stall or impede timely, well-informed, and broadly supported decision making. At many institutions (ours included), layers of governance have been added with each passing year,…

  13. Using IT Governance

    ERIC Educational Resources Information Center

    Brobst, Jan; Council, Chip

    2005-01-01

    The discussion in this article is intended to provide an examination of why top management, IT management, and internal auditors should be interested in IT governance. Some aspects of IT management will be described including implementation, auditing, availability, security, and alignment. One governance framework, COBIT, will be utilized as a…

  14. Government Information Policy.

    ERIC Educational Resources Information Center

    Dearstyne, Bruce W.; And Others

    1991-01-01

    Six articles discuss government information policy in context of technology and electronic records; policies on information resources management from OMB (Office of Management and Budget); state information resources, including Council of State Governments (CSG); state record laws and preservation of archival records; and management of electronic…

  15. Educational Governance in Denmark

    ERIC Educational Resources Information Center

    Moos, Lejf

    2014-01-01

    Denmark has entered global competition by expanding collaboration with European countries, which is profoundly impacting the public sector and school governance. Relations between the state and institutions are transforming from traditional democratic, public-sector models of governance into new forms characterized as corporate and market-driven…

  16. Policy Governance Revisited.

    ERIC Educational Resources Information Center

    Price, William J.

    2001-01-01

    An administrator trainer/former superintendent's experience suggests that corporate governance models don't fit the reality of school governance in many districts. Elected board members define their roles differently than their business counterparts and derive little or no monetary benefit from public service. The "new breed" resemble political…

  17. State and local governments

    NASA Technical Reports Server (NTRS)

    Barnes, Dennis

    1990-01-01

    The Virginia Space Grant Consortium approach to a close working relation to state and local governments is presented as a model for consideration. State government relations are especially important in that this is a primary resource in securing matching funds. Avenues for establishing these relationships are listed and discussed.

  18. Truth in Government.

    ERIC Educational Resources Information Center

    Cousins, Norman

    In this position paper the author examines truth in government. Examination of recent political events, especially in areas of foreign policy, reveals that the government has assumed the right to decide what truths are to be told and when they are to be told. To return to the principles developed by the members of the Constitutional Convention of…

  19. Physics and Government

    SciTech Connect

    Hendry, Nancy H.

    1999-08-24

    In defining the powers and duties of the three branches of government, the U.S. Constitution never explicitly referred to Science, except in the patent clause. But many technical responsibilities are implied in references to weights and measures, the census, and the like. Thomas Jefferson, John Adams, and in particular Benjamin Franklin, were highly literate in science, but it was their disciple, President John Quincy Adams who promoted as a matter of policy a direct role of the government in science--in particular with respect to astronomy, land surveys and navigation--all physical sciences. Some agencies of government--notably the National Bureau of Standards and the Department of Agriculture were founded in the early days of the Republic with scientific and technical missions. Since then the involvement of the government with science has waxed and waned but the major expansion of the interaction between physics and government occurred after World War II when physicists demonstrated the power of their craft during mobilization of science in support of the war effort. In discussing the interaction of physics with government we should distinguish ''science in government''--scientific input into policy making--from ''government in science,'' which is the support and management of that part of the overall scientific endeavor for which the government has responsibility. Let me turn first to the subject of physics in government. An overwhelming fraction of governmental decisions today have scientific and technical components; decisions ignoring these components are wasteful at best and can imperil the nation. For this reason governmental bodies at all levels solicit scientific advice--or at least give lip service to the need for such advice. When such advice was deliberately avoided, as President Reagan did before announcing his Strategic Defense Initiative in March 1983, the technically unattainable goal ''to make nuclear weapons impotent and obsolete'' was proclaimed.

  20. Technology for small spacecraft

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This report gives the results of a study by the National Research Council's Panel on Small Spacecraft Technology that reviewed NASA's technology development program for small spacecraft and assessed technology within the U.S. government and industry that is applicable to small spacecraft. The panel found that there is a considerable body of advanced technology currently available for application by NASA and the small spacecraft industry that could provide substantial improvement in capability and cost over those technologies used for current NASA small spacecraft. These technologies are the result of developments by commercial companies, Department of Defense agencies, and to a lesser degree NASA. The panel also found that additional technologies are being developed by these same entities that could provide additional substantial improvement if development is successfully completed. Recommendations for future technology development efforts by NASA across a broad technological spectrum are made.

  1. The Big Benefits of Smallness.

    ERIC Educational Resources Information Center

    Meier, Deborah W.

    1996-01-01

    Small schools (300 to 400 students) offer a real panacea for America's educational ills. New York City's celebrated Central Park East schools lack separate buildings, but have the climate and culture for developing democratic habits of heart and mind. Smallness can facilitate governance, respect, simplicity, safety, parent involvement,…

  2. Government - contractor interaction

    NASA Technical Reports Server (NTRS)

    Thomas, D. M.

    1983-01-01

    The development of the Administrative Contracting Officer represents an advance in the Government system of contract management because it provides an individual with knowledge, time, and a specialized function to insure performance of Government contracts. However, the development has created a dichotomy between the award and the post-award function which increases the adversary relationship with Government contractors. This paper advocates that this adversary relationship can be decreased if PCOs and ACOs are provided with opportunities to serve in the assignments of the other.

  3. Indian Employment in New Mexico State Government.

    ERIC Educational Resources Information Center

    Gerlach, Ernest J.; And Others

    Examining employment of American Indians in New Mexico state government, the New Mexico Advisory Committee to the U.S. Commission on Civil Rights found little change between small numbers of Indian employees in 1972 and 1974 figures. Though the State Personnel Office has made efforts to institute new programs and policies related to Indian…

  4. Towards Self-Government.

    ERIC Educational Resources Information Center

    Davies, Peter

    1980-01-01

    The author discusses the advantages of student self-government and describes the work of student committees at Belper High School, Derbyshire, in setting up a student coffee shop, planning school sports, and orienting new students. (SJL)

  5. LESS Government Act

    THOMAS, 112th Congress

    Rep. Latham, Tom [R-IA-4

    2011-06-15

    06/30/2011 Referred to the Subcommittee on Government Organization, Efficiency, and Financial Management . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. 3 CFR - Government Contracting

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... contract oversight could reduce such sums significantly. Government outsourcing for services also raises... governmental functions. Agencies and departments must operate under clear rules prescribing when outsourcing is... oversee acquisitions appropriately; and (4) clarify when governmental outsourcing for services is and...

  7. Government-Industry Data Exchange Program (GIDEP)

    NASA Technical Reports Server (NTRS)

    Richards, E. T.

    1974-01-01

    The Government-Industry Data Exchange Program (GIDEP) was originated in 1959 by the Army, Navy, and Air Force Ballistic Missile Agencies. Known at that time as IDEP--Interservice Data Exchange Program--its intent was to eliminate duplicate testing of parts and components by disseminating pertinent test data among Department of Defense contractors and various government agencies. In 1966 both the National Aeronautics and Space Administration and the Canadian Military Electronics Standards Agency (CAMESA) recognized the value of the data provided by the program and became participants. Today, GIDEP provides the interchange of specialized technical data to all the military services, participating government contractors and numerous government agencies such as the Atomic Energy Commission, Federal Aviation Administration, Defense Supply Agency, and the Small Business Administration.

  8. Shared health governance.

    PubMed

    Ruger, Jennifer Prah

    2011-07-01

    Health and Social Justice (Ruger 2009a ) developed the "health capability paradigm," a conception of justice and health in domestic societies. This idea undergirds an alternative framework of social cooperation called "shared health governance" (SHG). SHG puts forth a set of moral responsibilities, motivational aspirations, and institutional arrangements, and apportions roles for implementation in striving for health justice. This article develops further the SHG framework and explains its importance and implications for governing health domestically. PMID:21745082

  9. Shared health governance.

    PubMed

    Ruger, Jennifer Prah

    2011-07-01

    Health and Social Justice (Ruger 2009a ) developed the "health capability paradigm," a conception of justice and health in domestic societies. This idea undergirds an alternative framework of social cooperation called "shared health governance" (SHG). SHG puts forth a set of moral responsibilities, motivational aspirations, and institutional arrangements, and apportions roles for implementation in striving for health justice. This article develops further the SHG framework and explains its importance and implications for governing health domestically.

  10. Government Positions for Physicists.

    NASA Astrophysics Data System (ADS)

    Seiler, David

    2006-03-01

    There are a number of government agencies that employ physicists in a wide variety of jobs -- from student internships to post docs to full time staff positions. You can do real, creative, fore-front physics or pursue a wide range of leadership positions. The possibilities are almost unlimited and so is the impact your work can have on the government, academia, and industry. So how do you go about finding a government job? What qualities or abilities are deemed valuable? What are the advantages and disadvantages to working in the government? I will bring some personal experiences and observations from working in the government (one year as a rotator at the National Science Foundation in the Division of Materials Research and almost 18 years at the National Institute of Standards and Technology, both as a Group Leader and a Division Chief) to bear on these questions and more. Prior to my government career I was a physics professor pursuing research and teaching in academia.

  11. Health aid and governance in developing countries.

    PubMed

    Fielding, David

    2011-07-01

    Despite anecdotal evidence that the quality of governance in recipient countries affects the allocation of international health aid, there is no quantitative evidence on the magnitude of this effect, or on which dimensions of governance influence donor decisions. We measure health-aid flows over 1995-2006 for 109 aid recipients, matching aid data with measures of different dimensions of governance and a range of country-specific economic and health characteristics. Everything else being equal, countries with more political rights receive significantly more aid, but so do countries with higher corruption levels. The dependence of aid on political rights, even when we control for other governance indicators, suggests that health aid is sometimes used as an incentive to reward political reforms. PMID:20575152

  12. Health aid and governance in developing countries.

    PubMed

    Fielding, David

    2011-07-01

    Despite anecdotal evidence that the quality of governance in recipient countries affects the allocation of international health aid, there is no quantitative evidence on the magnitude of this effect, or on which dimensions of governance influence donor decisions. We measure health-aid flows over 1995-2006 for 109 aid recipients, matching aid data with measures of different dimensions of governance and a range of country-specific economic and health characteristics. Everything else being equal, countries with more political rights receive significantly more aid, but so do countries with higher corruption levels. The dependence of aid on political rights, even when we control for other governance indicators, suggests that health aid is sometimes used as an incentive to reward political reforms.

  13. The governance of disease control in Europe.

    PubMed

    Fox, Daniel M

    2012-12-01

    The eight articles on the governance of communicable disease control in Europe in this issue contribute information and insight to the literature on health politics, policy, and law. Each is a carefully researched and well-argued analysis of a subject on which its authors are experts. The set will be useful to scholars of comparative health policy as well as to specialists in European affairs. The articles also illustrate two methodological issues in conducting research on the governance of health policy. The first is that how researchers define governance influences what evidence they acquire and how they evaluate it. The second is that governance affects how diseases are conceptualized in order to make and implement policy. PMID:22899833

  14. 76 FR 52377 - National Small Business Development Center Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Update. --International Expansion. --Use of Social Media. --Member Roundtable. FOR FURTHER INFORMATION... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Small Business Development Center Advisory Board AGENCY: U.S. Small...

  15. 13 CFR 125.4 - What is the Government property sales assistance program?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.4 What is the Government property sales assistance program? (a) The purpose of SBA's Government property sales assistance program is to: (1) Insure that small... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false What is the Government...

  16. Affective Learning.

    ERIC Educational Resources Information Center

    Brown, Charles T.

    This paper addresses itself to the question, "What does feeling have to do with knowing?" Two movements in affective education are discussed which have come into focus in recent years and which attempt to define the relationship between knowing and feeling. The first, a conscious application of the role of arousal in learning, emphasizes arousal…

  17. Political Trends Affecting Nonmetropolitan America.

    ERIC Educational Resources Information Center

    Nachtigal, Paul M.

    There are two stories about political trends affecting nonmetropolitan America. The old story, which is the story of declining rural population and declining rural influence on public policy formation, has its roots in early deliberations about governance in this country. Jefferson's republicanism focused on direct citizen involvement in decision…

  18. Government Information Access: A decisive Factor for E-Government

    NASA Astrophysics Data System (ADS)

    Xia, Yikun; Huang, Cui

    In recent years we are witnessing enormous development of e-government, which has brought about great changes in our society. This study examines the relationship between the levels of e-government and the quality of government information access, pointing out that e-government principles are based on the assumption that government information should be accessed among all kinds of organizations. In contrast to government webs' rapid growth, the low quality of government information access has been a dilemma which impacts the usability and efficiency of e-government. This paper also analyzes blocking factors about information access in China, draw a conclusion that on-line government information access should be the key factor of e-government which steps should be taken to enhance accessibility to government information.

  19. The American Economy: Government's Role, Citizen's Choice. Second Edition. [Student Text] and Teacher's Guide.

    ERIC Educational Resources Information Center

    Close Up Foundation, Arlington, VA.

    The Student Text and Teacher's Guide examine the government's role in the U.S. economy and how the choices made by the government in Washington affect each individual. The student text is divided into four chapters. Chapter 1, "Government's Role in the Economy," discusses why government gets involved in the economy and examines the social and…

  20. All Holdings Are Local: Archivists and Local Government Archives

    ERIC Educational Resources Information Center

    James, Russell D.

    2004-01-01

    Archivists working in repositories that contain local government records play an integral role within the local community. Unlike their colleagues in state, regional, or national repositories, the local government archivist concentrates on a small geographic region and demonstrates knowledge of the politics, history, and socio-economics of the…

  1. 13 CFR 120.711 - What rules govern Intermediaries?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false What rules govern Intermediaries? 120.711 Section 120.711 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Microloan Program § 120.711 What rules govern Intermediaries? Intermediaries must operate in accordance...

  2. 13 CFR 120.711 - What rules govern Intermediaries?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false What rules govern Intermediaries? 120.711 Section 120.711 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Microloan Program § 120.711 What rules govern Intermediaries? Intermediaries must operate in accordance...

  3. 13 CFR 120.711 - What rules govern Intermediaries?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What rules govern Intermediaries? 120.711 Section 120.711 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Microloan Program § 120.711 What rules govern Intermediaries? Intermediaries must operate in accordance...

  4. 13 CFR 120.711 - What rules govern Intermediaries?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false What rules govern Intermediaries? 120.711 Section 120.711 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Microloan Program § 120.711 What rules govern Intermediaries? Intermediaries must operate in accordance...

  5. 13 CFR 120.711 - What rules govern Intermediaries?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false What rules govern Intermediaries? 120.711 Section 120.711 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Microloan Program § 120.711 What rules govern Intermediaries? Intermediaries must operate in accordance...

  6. Local government`s pollution prevention program

    SciTech Connect

    Swanson, D.

    1996-12-31

    The pollution prevention program operated by the Health Department of Boulder County is called Business Partners for a Clean Environment (Business Partners). It is a cooperative effort among local businesses, the City of Boulder, Boulder County, and the Boulder Chamber of Commerce. This nonregulatory, incentive-based program provides industry with pollution prevention information and technical assistance necessary to reduce and/or eliminate environmental waste. This paper provides an overview of the program development, creation of partnerships and trust, and some of the results from implementation of the program. Following the first 18 months of the program, 35 businesses were recognized as Business Partners. The Business Partners program has also received an achievement award from the National Association of Counties for promoting {open_quotes}responsible, responsive, and effective government{close_quotes} and two governor`s awards from the State of Colorado. Participating businesses have demonstrated that a pollution prevention program can reduce environmental waste, increase employee safety, and decrease costs. 4 refs., 4 figs., 5 tabs.

  7. Governance Structure: Palomar College.

    ERIC Educational Resources Information Center

    Palomar Coll., San Marcos, CA.

    The governance structure of Palomar College (PC) in San Marcos, California, is defined in the plan described in this document. Introductory material indicates that the plan was designed to provide appropriate representation for each of PC's constituent groups, delineate committee responsibilities and reporting relationships, establish the…

  8. Ethics in Government.

    ERIC Educational Resources Information Center

    Update on Law-Related Education, 1990

    1990-01-01

    Presents a lesson developed by the Center for Civic Education giving secondary students the opportunity to explore ethical issues in government from the perspective of corrective justice. Outlines role plays and other class activities based on a fictitious ethics scandal involving bribery. Identifies specific questions to be asked on issues of…

  9. In Brief: Open government

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2010-03-01

    U.S. President Barack Obama's Memorandum on Transparency and Open Government requires federal agencies to take steps toward increased transparency, public participation, and collaboration. Agencies are accepting suggestions until 19 March 2010. For more information, visit http://www.whitehouse.gov/open and http://www.usa.gov/webcontent/open/tool_poc.shtml.

  10. Governance Final Briefing Paper

    ERIC Educational Resources Information Center

    Washington State Board of Education, 2011

    2011-01-01

    One of the State Board of Education's (SBE) strategic plan goals is to advocate for an effective, accountable governance structure for public education in Washington. The development of this goal comes from Board members' experiences over the last five years to understand and address the complexity of Washington's education system and their role…

  11. Government in the Community.

    ERIC Educational Resources Information Center

    Curran, Donald J.; And Others

    1985-01-01

    This issue begins with information on new economic education curriculum materials and includes a conceptual introduction to the relationship between local government and the economy. Following this, four instructional units are provided. The first unit, called "Communities Need Rules," is intended for preschool and kindergarten children. Students…

  12. Governance Review without Tears

    ERIC Educational Resources Information Center

    Davis, Lynn K.; Page, Deborah L.

    2006-01-01

    The faculty at the Raymond Walters College of the University of Cincinnati recently conceived, developed, and implemented a complete governance review that the faculty approved unanimously. Raymond Walters College is one of the sixteen colleges of the University of Cincinnati which offers transfer programs, associate degrees, and technical…

  13. Biology and the Government

    ERIC Educational Resources Information Center

    Reid, Roger D.

    1969-01-01

    Emphasizes the social implications of biological knowledge and discusses two main government roles in biology: (1) a creative and supportive role, including support of education and research, (2) control, regulation and protection related to the applications of biological knowledge. Public control is considered necessary in areas such as food and…

  14. Governance of Public Education.

    ERIC Educational Resources Information Center

    Moran, K. D.; Martinez, Robert P.

    Two basic questions underlie school law battles: Who governs public education? What are the limits of the school board's power? Examples can be seen in litigation regarding questions such as State-local responsibility in school finance and assessment, the public release of district-wide test scores, the authority of arbitrators to make educational…

  15. Governance and Civic Education.

    ERIC Educational Resources Information Center

    Thompson, Ekundayo J. D., Ed.

    This book contains 13 papers on the socioeconomic development, legal, gender, philosophical, and human rights dimensions of state governance within the context of social, economic, and political processes in Sierra Leone and Kenya. The Political Literacy and Civic Education (PLACE) Project, which was sponsored by the British Overseas Development…

  16. Independent School Governance.

    ERIC Educational Resources Information Center

    Beavis, Allan K.

    Findings of a study that examined the role of the governing body in the independent school's self-renewing processes are presented in this paper. From the holistic paradigm, the school is viewed as a self-renewing system that is able to maintain its identity despite environmental changes through existing structures that define and create…

  17. Small Business Innovations

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Under an Army Small Business Innovation Research (SBIR) grant, Symbiotics, Inc. developed a software system that permits users to upgrade products from standalone applications so they can communicate in a distributed computing environment. Under a subsequent NASA SBIR grant, Symbiotics added additional tools to the SOCIAL product to enable NASA to coordinate conventional systems for planning Shuttle launch support operations. Using SOCIAL, data may be shared among applications in a computer network even when the applications are written in different programming languages. The product was introduced to the commercial market in 1993 and is used to monitor and control equipment for operation support and to integrate financial networks. The SBIR program was established to increase small business participation in federal R&D activities and to transfer government research to industry. InQuisiX is a reuse library providing high performance classification, cataloging, searching, browsing, retrieval and synthesis capabilities. These form the foundation for software reuse, producing higher quality software at lower cost and in less time. Software Productivity Solutions, Inc. developed the technology under Small Business Innovation Research (SBIR) projects funded by NASA and the Army and is marketing InQuisiX in conjunction with Science Applications International Corporation (SAIC). The SBIR program was established to increase small business participation in federal R&D activities and to transfer government research to industry.

  18. COTSAT Small Spacecraft Cost Optimization for Government and Commercial Use

    NASA Technical Reports Server (NTRS)

    Swank, Aaron J.; Bui, David; Dallara, Christopher; Ghassemieh, Shakib; Hanratty, James; Jackson, Evan; Klupar, Pete; Lindsay, Michael; Ling, Kuok; Mattei, Nicholas; Mayer, David; Quigley, Emmett; Spremo, Stevan; Young, Zion

    2009-01-01

    Cost Optimized Test of Spacecraft Avionics and Technologies (COTSAT-1) is an ongoing spacecraft research and development project at NASA Ames Research Center (ARC). The prototype spacecraft, also known as CheapSat, is the first of what could potentially be a series of rapidly produced low-cost spacecraft. The COTSAT-1 team is committed to realizing the challenging goal of building a fully functional spacecraft for $500K parts and $2.0M labor. The project's efforts have resulted in significant accomplishments within the scope of a limited budget and schedule. Completion and delivery of the flight hardware to the Engineering Directorate at NASA Ames occurred in February 2009 and a cost effective qualification program is currently under study. The COTSAT-1 spacecraft is now located at NASA Ames Research Center and is awaiting a cost effective launch opportunity. This paper highlights the advancements of the COTSAT-1 spacecraft cost reduction techniques.

  19. Transforming organizational culture through nursing shared governance.

    PubMed

    Newman, Karen Profitt

    2011-03-01

    Nursing shared governance (NSG) provides a framework for the professionalization of nursing, provides a broader distribution of decision making across the profession, and allocates decisions based on accountability and role expectations. Shared governance defines staff-based decisions, accountability, roles, and ownership of staff in those activities that directly affect nurses' lives and practice. Although NSG is a somewhat ambiguous concept with a vast application, examining it from the perspective of structure, process, and outcomes can more clearly outline a successful strategy for implementation and growth. PMID:21320660

  20. Globalization and the Governance of Education in Viet Nam

    ERIC Educational Resources Information Center

    London, Jonathan D.

    2010-01-01

    In a globalizing world, local and global governance arrangements are increasingly interdependent, which produces harmonization in some instances and new tensions and contradictions in others. Analysis shows that successive waves of globalization have affected the governance of education in Viet Nam differently. It shows that the globalization of…

  1. Changing Governance and Authority Relations in the Public Sciences

    ERIC Educational Resources Information Center

    Whitley, Richard

    2011-01-01

    Major changes in the governance of higher education and the public sciences have taken place over the past 40 or so years in many OECD countries. These have affected the nature of authority relationships governing research priorities and the evaluation of results. In particular, the increasing exogeneity, formalisation and substantive nature of…

  2. 12 CFR 745.10 - Accounts held by government depositors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Accounts held by government depositors. 745.10 Section 745.10 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS SHARE INSURANCE AND APPENDIX Clarification and Definition of Account Insurance Coverage § 745.10 Accounts held by government depositors....

  3. 12 CFR 745.10 - Accounts held by government depositors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Accounts held by government depositors. 745.10 Section 745.10 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS SHARE INSURANCE AND APPENDIX Clarification and Definition of Account Insurance Coverage § 745.10 Accounts held by government depositors....

  4. 12 CFR 745.10 - Accounts held by government depositors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Accounts held by government depositors. 745.10 Section 745.10 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS SHARE INSURANCE AND APPENDIX Clarification and Definition of Account Insurance Coverage § 745.10 Accounts held by government depositors....

  5. Understanding public confidence in government to prevent terrorist attacks.

    SciTech Connect

    Baldwin, T. E.; Ramaprasad, A,; Samsa, M. E.; Decision and Information Sciences; Univ. of Illinois at Chicago

    2008-04-02

    A primary goal of terrorism is to instill a sense of fear and vulnerability in a population and to erode its confidence in government and law enforcement agencies to protect citizens against future attacks. In recognition of its importance, the Department of Homeland Security includes public confidence as one of the principal metrics used to assess the consequences of terrorist attacks. Hence, a detailed understanding of the variations in public confidence among individuals, terrorist event types, and as a function of time is critical to developing this metric. In this exploratory study, a questionnaire was designed, tested, and administered to small groups of individuals to measure public confidence in the ability of federal, state, and local governments and their public safety agencies to prevent acts of terrorism. Data was collected from three groups before and after they watched mock television news broadcasts portraying a smallpox attack, a series of suicide bomber attacks, a refinery explosion attack, and cyber intrusions on financial institutions, resulting in identity theft. Our findings are: (a) although the aggregate confidence level is low, there are optimists and pessimists; (b) the subjects are discriminating in interpreting the nature of a terrorist attack, the time horizon, and its impact; (c) confidence recovery after a terrorist event has an incubation period; and (d) the patterns of recovery of confidence of the optimists and the pessimists are different. These findings can affect the strategy and policies to manage public confidence after a terrorist event.

  6. 75 FR 1662 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Administration, Office of Government Contracting, 409 3rd Street, SW., Suite 8800, Washington, DC 20416. FOR..., Office of Government Contracting. BILLING CODE 8025-01-P ... From the Federal Register Online via the Government Publishing Office ] SMALL...

  7. 75 FR 28077 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... Government Contracting and should specifically state the class (or classes) of products for which the waiver.... Karen Hontz, Director for Government Contracting. BILLING CODE 8025-01-P ... From the Federal Register Online via the Government Publishing Office SMALL...

  8. 75 FR 42173 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... Government Contracting. BILLING CODE 8025-01-P ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS... products to the Federal government. The effect of this waiver will be to allow otherwise qualified...

  9. An Analysis of the Treatment of Corporate Influence on Government by United States History and American Government High School Textbooks

    ERIC Educational Resources Information Center

    Neumann, Richard

    2014-01-01

    This article reports on an investigation to explore the possibility that ideology might be expressed in the treatment of corporate influence on federal government by social studies textbooks. Two textbooks were examined in the study--United States history and American government. Corporate influence involves activities that affect election and…

  10. [Affective dependency].

    PubMed

    Scantamburlo, G; Pitchot, W; Ansseau, M

    2013-01-01

    Affective dependency is characterized by emotional distress (insecure attachment) and dependency to another person with a low self-esteem and reassurance need. The paper proposes a reflection on the definition of emotional dependency and the confusion caused by various denominations. Overprotective and authoritarian parenting, cultural and socio-environmental factors may contribute to the development of dependent personality. Psychological epigenetic factors, such as early socio-emotional trauma could on neuronal circuits in prefronto-limbic regions that are essential for emotional behaviour.We also focus on the interrelations between dependent personality, domestic violence and addictions. The objective for the clinician is to propose a restoration of self-esteem and therapeutic strategies focused on autonomy.

  11. [Affective dependency].

    PubMed

    Scantamburlo, G; Pitchot, W; Ansseau, M

    2013-01-01

    Affective dependency is characterized by emotional distress (insecure attachment) and dependency to another person with a low self-esteem and reassurance need. The paper proposes a reflection on the definition of emotional dependency and the confusion caused by various denominations. Overprotective and authoritarian parenting, cultural and socio-environmental factors may contribute to the development of dependent personality. Psychological epigenetic factors, such as early socio-emotional trauma could on neuronal circuits in prefronto-limbic regions that are essential for emotional behaviour.We also focus on the interrelations between dependent personality, domestic violence and addictions. The objective for the clinician is to propose a restoration of self-esteem and therapeutic strategies focused on autonomy. PMID:23888587

  12. Ethics and constitutional government.

    PubMed

    Albright, James A

    2007-01-01

    The term ethics refers to a set of principles that govern acceptable, proper conduct. Attacks on the Constitution of the United States pose the most serious breach of ethics today. Our country was founded as a republic, not as a democracy. Our Founding Fathers' main concern was to protect citizens from the power of the federal government, so constitutionally, the central government has little or no authority over individual citizens except on federal property. One of the major problems today is the fact that we now have professional politicians. This is due in large part to the lure of financial gain from countless special interest groups. This would change under constitutional law because the federal budget would decrease drastically. Article 1 states that all legislative power is vested in Congress. Congress has only 18 enumerated powers, and almost half of these pertain to defense of the country. Many of our current problems are due to regulatory agencies that have become independent fiefdoms with unconstitutional legislative, as well as executive and judicial, powers. The regulatory agency most relevant to medicine, both clinical care and research, is the FDA. It is now obvious that its basic structure needs to be changed or abolished because its actions are identical to those inherent in authoritarian systems. Constructive change could come from Congress, but it would be most desirable if the Supreme Court would take the lead and reestablish the authority of the Constitution as the Supreme Law of the Land. The FDA's function could be limited to the determination of safety, but preferably its mission would be altered to that of product certification. Defenders of the current system claim that such a drastic change would be too dangerous and their prime example is thalidomide. But it is now known that the market has already solved that problem prior to the government-imposed sanctions. Realistically, market forces and their ramifications, including our legal

  13. Ethics and constitutional government.

    PubMed

    Albright, James A

    2007-01-01

    The term ethics refers to a set of principles that govern acceptable, proper conduct. Attacks on the Constitution of the United States pose the most serious breach of ethics today. Our country was founded as a republic, not as a democracy. Our Founding Fathers' main concern was to protect citizens from the power of the federal government, so constitutionally, the central government has little or no authority over individual citizens except on federal property. One of the major problems today is the fact that we now have professional politicians. This is due in large part to the lure of financial gain from countless special interest groups. This would change under constitutional law because the federal budget would decrease drastically. Article 1 states that all legislative power is vested in Congress. Congress has only 18 enumerated powers, and almost half of these pertain to defense of the country. Many of our current problems are due to regulatory agencies that have become independent fiefdoms with unconstitutional legislative, as well as executive and judicial, powers. The regulatory agency most relevant to medicine, both clinical care and research, is the FDA. It is now obvious that its basic structure needs to be changed or abolished because its actions are identical to those inherent in authoritarian systems. Constructive change could come from Congress, but it would be most desirable if the Supreme Court would take the lead and reestablish the authority of the Constitution as the Supreme Law of the Land. The FDA's function could be limited to the determination of safety, but preferably its mission would be altered to that of product certification. Defenders of the current system claim that such a drastic change would be too dangerous and their prime example is thalidomide. But it is now known that the market has already solved that problem prior to the government-imposed sanctions. Realistically, market forces and their ramifications, including our legal

  14. Shared Health Governance

    PubMed Central

    Ruger, Jennifer Prah

    2014-01-01

    Health and Social Justice (Ruger 2009a) developed the “health capability paradigm,” a conception of justice and health in domestic societies. This idea undergirds an alternative framework of social cooperation called “shared health governance” (SHG). SHG puts forth a set of moral responsibilities, motivational aspirations, and institutional arrangements, and apportions roles for implementation in striving for health justice. This article develops further the SHG framework and explains its importance and implications for governing health domestically. PMID:21745082

  15. Small Wins.

    ERIC Educational Resources Information Center

    Rhatigan, James J.; Schuh, John H.

    2003-01-01

    Examines how it easy for people to overlook small successes when they are overwhelmed by and preoccupied with large projects and goals. Explores the concept of "small wins" in organizational theory, which have the potential to become a prominent part of institutional culture and impact organizational behavior and change. (GCP)

  16. Small Cultures.

    ERIC Educational Resources Information Center

    Holliday, Adrian

    1999-01-01

    Presents a notion of small culture as an alternative to what has become the default notion of large culture in applied linguistics, social science, and popular usage. A small-culture view of English-language curriculum settings reveals mismatches between professional-academic and organizational cultures at the mezzo level of the institution. (VWL)

  17. Digital government and public health.

    PubMed

    Fountain, Jane E

    2004-10-01

    Digital government is typically defined as the production and delivery of information and services inside government and between government and the public using a range of information and communication technologies. Two types of government relationships with other entities are government-to-citizen and government-to-government relationships. Both offer opportunities and challenges. Assessment of a public health agency's readiness for digital government includes examination of technical, managerial, and political capabilities. Public health agencies are especially challenged by a lack of funding for technical infrastructure and expertise, by privacy and security issues, and by lack of Internet access for low-income and marginalized populations. Public health agencies understand the difficulties of working across agencies and levels of government, but the development of new, integrated e-programs will require more than technical change - it will require a profound change in paradigm.

  18. Clinical governance. Scope to improve.

    PubMed

    Walshe, K; Freeman, T; Latham, L; Spurgeon, P; Wallace, L

    2000-10-26

    A survey of all 47 trusts in the West Midlands found that clinical governance had not been advanced beyond the production of strategies, establishing committees and appointing leads. There is little evidence of the cultural change clinical governance requires. Clinical governance has yet to make a real difference at the clinical workface. PMID:11138206

  19. Shared Governance: The Next Generation.

    ERIC Educational Resources Information Center

    Lovas, John C.; And Others

    This document contains three papers which present information from various perspectives on aspects of shared governance at De Anza College, in Cupertino, California. First, "Shared Governance: The Next Generation," by John C. Lovas, provides a brief history of governance in the Foothill-De Anza Community College District, and suggests some of the…

  20. Local Government: The Learning Laboratory.

    ERIC Educational Resources Information Center

    Degelman, Charles, Ed.

    2001-01-01

    This issue of "Service-Learning Network" looks at the ways that service learning can transform local government into a learning laboratory for civic education. The first article, "Creating the Missing Link: Local Government, Service Learning, and Civic Education" (Todd Clark), introduces the issue. "Service Learning and Local Government" (Ann…

  1. The P21-activated kinase expression pattern is different in non-small cell lung cancer and affects lung cancer cell sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors.

    PubMed

    Liu, Yang; Wang, Si; Dong, Qian-Ze; Jiang, Gui-Yang; Han, Yong; Wang, Liang; Wang, En-Hua

    2016-03-01

    Exploring methods for increasing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) sensitivity has become a major focus in non-small cell lung cancer (NSCLC). Major downstream effectors of the Rho family small guanosine triphosphatases, P21-activated kinases (PAKs) activate the main signaling pathways downstream of EGFR and thus promote tumor cell proliferation. In this study, we explored the expression pattern of phosphorylated PAKs in NSCLC and their potential value as drug targets for treating cancer. The expression and prognostic significance of phosphorylated group I and II PAKs were evaluated in 182 patients with NSCLC. Immunohistochemical analysis revealed low group I PAK expression in normal lung tissues and increased expressed in the cytoplasm, particularly in lung squamous cell carcinoma. Abnormal group I PAK expression was associated with lymph node metastases and high tumor-node-metastases (TNM) stage in NSCLC patients and correlated with poor prognosis. We used group I PAK inhibitor (IPA3) to specifically decrease group I PAK activity in human lung cancer cell lines. Decreased group I PAK activity inhibited cell proliferation and combined IPA3 and EGFR-TKI (gefitinib) treatment inhibited cell proliferation in an obvious manner. Together, our results revealed the PAK expression pattern in NSCLC, and a role for group I PAK in cell proliferation, which provides evidence that decreased PAK activity may have a potential application as a molecular targeted therapy in advanced NSCLC.

  2. 13 CFR 121.509 - What is the size standard for leasing of Government land for coal mining?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... leasing of Government land for coal mining? 121.509 Section 121.509 Business Credit and Assistance SMALL... leasing of Government land for coal mining? A concern is small for this purpose if it: (a) Together with... actual mining operations of the tract; and (c) Agrees that if it subleases the Government land, it...

  3. 49 CFR 173.7 - Government operations and materials.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certified by the Department of Energy against packaging standards equivalent to those specified in 10 CFR... Note: For Federal Register citations affecting § 173.7, see the List of CFR Sections Affected, which... 49 Transportation 2 2013-10-01 2013-10-01 false Government operations and materials. 173.7...

  4. 49 CFR 173.7 - Government operations and materials.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certified by the Department of Energy against packaging standards equivalent to those specified in 10 CFR... Note: For Federal Register citations affecting § 173.7, see the List of CFR Sections Affected, which... 49 Transportation 2 2012-10-01 2012-10-01 false Government operations and materials. 173.7...

  5. 49 CFR 173.7 - Government operations and materials.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... certified by the Department of Energy against packaging standards equivalent to those specified in 10 CFR... Note: For Federal Register citations affecting § 173.7, see the List of CFR Sections Affected which... 49 Transportation 2 2010-10-01 2010-10-01 false Government operations and materials. 173.7...

  6. SmallSat Database

    NASA Technical Reports Server (NTRS)

    Petropulos, Dolores; Bittner, David; Murawski, Robert; Golden, Bert

    2015-01-01

    The SmallSat has an unrealized potential in both the private industry and in the federal government. Currently over 70 companies, 50 universities and 17 governmental agencies are involved in SmallSat research and development. In 1994, the U.S. Army Missile and Defense mapped the moon using smallSat imagery. Since then Smart Phones have introduced this imagery to the people of the world as diverse industries watched this trend. The deployment cost of smallSats is also greatly reduced compared to traditional satellites due to the fact that multiple units can be deployed in a single mission. Imaging payloads have become more sophisticated, smaller and lighter. In addition, the growth of small technology obtained from private industries has led to the more widespread use of smallSats. This includes greater revisit rates in imagery, significantly lower costs, the ability to update technology more frequently and the ability to decrease vulnerability of enemy attacks. The popularity of smallSats show a changing mentality in this fast paced world of tomorrow. What impact has this created on the NASA communication networks now and in future years? In this project, we are developing the SmallSat Relational Database which can support a simulation of smallSats within the NASA SCaN Compatability Environment for Networks and Integrated Communications (SCENIC) Modeling and Simulation Lab. The NASA Space Communications and Networks (SCaN) Program can use this modeling to project required network support needs in the next 10 to 15 years. The SmallSat Rational Database could model smallSats just as the other SCaN databases model the more traditional larger satellites, with a few exceptions. One being that the smallSat Database is designed to be built-to-order. The SmallSat database holds various hardware configurations that can be used to model a smallSat. It will require significant effort to develop as the research material can only be populated by hand to obtain the unique data

  7. Practice Governance 101, v. 2013.

    PubMed

    Hayes, David F

    2013-03-01

    Consensus governance is a principal weakness leading to group malfunction and failure. Inadequate group governance produces inadequate decisions, leading to inconsistent patient care, inadequate responses to marketplace challenges, and disregard for customers and strategic partners. The effectiveness of consensus management is limited by the pervasive incomplete knowledge and personal biases of partners. Additional structural weaknesses of group behavior include information cascade, the wisdom of the crowd, groupthink, pluralistic ignorance, analysis paralysis, peer pressure, and the herding instinct. Usual corporate governance is, by necessity, the governance model of choice. Full accountability of the decider(s) is the defining requirement of all successful governance models. PMID:23571058

  8. Practice Governance 101, v. 2013.

    PubMed

    Hayes, David F

    2013-03-01

    Consensus governance is a principal weakness leading to group malfunction and failure. Inadequate group governance produces inadequate decisions, leading to inconsistent patient care, inadequate responses to marketplace challenges, and disregard for customers and strategic partners. The effectiveness of consensus management is limited by the pervasive incomplete knowledge and personal biases of partners. Additional structural weaknesses of group behavior include information cascade, the wisdom of the crowd, groupthink, pluralistic ignorance, analysis paralysis, peer pressure, and the herding instinct. Usual corporate governance is, by necessity, the governance model of choice. Full accountability of the decider(s) is the defining requirement of all successful governance models.

  9. Governance for personal health records.

    PubMed

    Reti, Shane R; Feldman, Henry J; Safran, Charles

    2009-01-01

    Personal health records (PHR) are a modern health technology with the ability to engage patients more fully in their healthcare. Despite widespread interest, there has been little discussion around PHR governance at an organizational level. We develop a governance model and compare it to the practices of some of the early PHR adopters, including hospitals and ambulatory care settings, insurers and health plans, government departments, and commercial sectors. Decision-making structures varied between organizations. Business operations were present in all groups, but patients were not represented in any of the governance structures surveyed. To improve patient-centered care, policy making for PHRs needs to include patient representation at a governance level.

  10. Globalization and emerging governance modalities.

    PubMed

    Neubauer, Deane Edward

    2005-09-01

    This paper explores the possibilities for global governance effectively dealing with the international transmission of disease. First, zoonotic regulation and control pose a special case for public health agencies, and this paper proposes a propositional model for an effective public health stance. Second, globalization dynamics are briefly reviewed in terms of an emerging consensus on the need for global governance in public health. Third, a brief examination of global governance modalities suggests that a strong global governance case has distinct limitations (despite its possible justification); an exploration of contemporary directions in global governance follows. Finally, the paper examines the phenomenon of contemporary zoonotic control within the conditions of an effective regulatory regime.

  11. Government-to-Government E-Government: A Case Study of a Federal Financial Program

    ERIC Educational Resources Information Center

    Faokunla, Olumide Adegboyega

    2012-01-01

    The problem with the study of the concept of electronic government (e-Gov) is that scholars in the field have not adequately explored various dimensions of the concept. Literature on e-Gov is replete with works on the form of government to consumer e-Gov. Much less work had been done on the government to government (G2G) e-Gov. This qualitative…

  12. Nanomedicine: Governing uncertainties

    NASA Astrophysics Data System (ADS)

    Trisolino, Antonella

    Nanomedicine is a promising and revolutionary field to improve medical diagnoses and therapies leading to a higher quality of life for everybody. Huge benefits are expected from nanomedicine applications such as in diagnostic and therapeutic field. However, nanomedicine poses several issues on risks to the human health. This thesis aims to defense a perspective of risk governance that sustains scientific knowledge process by developing guidelines and providing the minimum safety standards acceptable to protect the human health. Although nanomedicine is in an early stage of its discovery, some cautious measures are required to provide regulatory mechanisms able to response to the unique set of challenges associated to nanomedicine. Nanotechnology offers an unique opportunity to intensify a major interplay between different disciplines such as science and law. This multidisciplinary approach can positively contributes to find reliable regulatory choices and responsive normative tools in dealing with challenges of novel technologies.

  13. 13 CFR 124.405 - How does a Participant obtain Federal Government surplus property?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... See 41 CFR subpart 101-44.2. (2) Each Participant seeking to acquire Federal Government surplus... Federal Government surplus property? 124.405 Section 124.405 Business Credit and Assistance SMALL BUSINESS... Development Business Development § 124.405 How does a Participant obtain Federal Government surplus...

  14. 13 CFR 124.405 - How does a Participant obtain Federal Government surplus property?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... See 41 CFR subpart 101-44.2. (2) Each Participant seeking to acquire Federal Government surplus... Federal Government surplus property? 124.405 Section 124.405 Business Credit and Assistance SMALL BUSINESS... Development Business Development § 124.405 How does a Participant obtain Federal Government surplus...

  15. 13 CFR 124.405 - How does a Participant obtain Federal Government surplus property?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... See 41 CFR subpart 101-44.2. (2) Each Participant seeking to acquire Federal Government surplus... Federal Government surplus property? 124.405 Section 124.405 Business Credit and Assistance SMALL BUSINESS... Development Business Development § 124.405 How does a Participant obtain Federal Government surplus...

  16. 13 CFR 124.405 - How does a Participant obtain Federal Government surplus property?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... See 41 CFR subpart 101-44.2. (2) Each Participant seeking to acquire Federal Government surplus... Federal Government surplus property? 124.405 Section 124.405 Business Credit and Assistance SMALL BUSINESS... Development Business Development § 124.405 How does a Participant obtain Federal Government surplus...

  17. 13 CFR 124.405 - How does a Participant obtain Federal Government surplus property?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... See 41 CFR subpart 101-44.2. (2) Each Participant seeking to acquire Federal Government surplus... Federal Government surplus property? 124.405 Section 124.405 Business Credit and Assistance SMALL BUSINESS... Development Business Development § 124.405 How does a Participant obtain Federal Government surplus...

  18. 13 CFR 125.1 - What definitions are important to SBA's Government Contracting Programs?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SBA's Government Contracting Programs? 125.1 Section 125.1 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.1 What definitions are important to SBA's Government Contracting Programs? (a) Chief Acquisition Officer means the employee of a Federal...

  19. Governance Challenges in Telecoupled Food Systems

    NASA Astrophysics Data System (ADS)

    Eakin, H.; Mahanti, A.; Rueda, X.

    2015-12-01

    Distal connections increasingly influence food systems' governance: social actors in one geographic context produce intended and unintended consequences in distant locations, coupling the dynamics of socio-ecological systems. While these linkages are not new, economic globalization, urbanization and the dynamics of consumer preferences have accentuated these 'telecoupled' relationships in food systems. Telecoupling refers to the unexpected causal interactions among human-environment systems that were otherwise not linked. This paper presents a framework for evaluating telecoupling processes and outcomes in food systems, focusing on how the disparate scales of drivers and outcomes, diverse values of actors involved, and spatial and social distance combine to challenge socio-ecological system governance. We draw from two examples of food systems (coffee and maize) to argue that telecoupling, as a challenge for food systems, emerges when the institutions and mechanisms of governance acting over one system do not account for the consequences and interactions involving a different system. Telecoupling can stimulate new forms of governance, such as the development of codes of conduct and certification schemes, with positive impacts on food and livelihood security. Our cases suggest that the emergence of new governance arrangements is at least partially contingent on the prior existence of alternative social networks, which cultivate shared values, meanings and goals in food systems, as well as the capacity of affected actors to mobilize political influence and demonstrate plausible causal links. In the absence of such networks and associated capacities, the prior governance arrangements, although poorly adjusted to the new circumstances, are likely to persist, reinforcing existing power relations and the probability of undesirable social and ecological outcomes.

  20. 13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business....

  1. 13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business....

  2. 13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business....

  3. 13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business....

  4. 13 CFR 121.511 - What is the size standard for buying Government-owned petroleum?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... buying Government-owned petroleum? 121.511 Section 121.511 Business Credit and Assistance SMALL BUSINESS... Government-owned petroleum? A concern is small for this purpose if it is primarily engaged in petroleum refining and meets the size standard for a petroleum refining business....

  5. Why governance? A challenge to good governance of biobanks.

    PubMed

    Browne, Katharine

    2015-12-01

    In this commentary on Karla Stroud and Kieran O'Doherty's 'Ethically Sustainable Governance in the Biobanking of Eggs and Embryos for Research' (2015) I call into question the need for good governance to overcome the challenges facing biobanking of eggs and embryos. I argue that the principles of good governance for biobanking that Stroud and O'Doherty outline come up short in providing concrete normative guidance to resolve the challenges associated with a biobank for eggs and embryos.

  6. The Future of Government Funding for Persons with Disabilities: Some Key Factors.

    ERIC Educational Resources Information Center

    Ross, E. Clarke

    1980-01-01

    The paper identifies and discusses key factors associated with government funding for disabled individuals. An introductory section traces the growth of public expenditures in recent years. Five key factors affecting government funding are examined (sample subtopics in parentheses): state government tax and spending limits (Proposition 13 and the…

  7. 77 FR 24611 - Removal of Regulations Requiring 3% Withholding by Government Entities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... affects government entities that would have been required to withhold and report tax from payments to... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY... Government Entities AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Final regulations....

  8. The Usage of E-Governance Applications by Higher Education Students

    ERIC Educational Resources Information Center

    Öktem, M. Kemal; Demirhan, Kamil; Demirhan, Haydar

    2014-01-01

    This study aims to analyze the factors affecting the Internet usage of university students using e-governance applications. It is important to examine these factors to understand why the online citizen participation is not increasing as expected, while Information and Communication Technologies (ICT) usage is improving in governance. Governance is…

  9. Government`s response to the competitiveness problem

    SciTech Connect

    Gover, J.; Huray, P.; Carayannis, E.

    1997-11-01

    This paper presents an analysis of how the US government responded to the concern in the 1980`s that US companies were experiencing problems of competitiveness in international markets. By the mid 1980`s there was great and growing concern throughout the US that US companies were experiencing difficulties in international competition. Pressure on Congress to take action came from constituents seeking jobs and companies that would directly benefit (this usually means receive public money) from programs that Congress might initiate. The fact that most constituent calls to Congress were about job creation was lost in the on-rush of R&D performers seeking funds for their favorite R&D project. In response, Congress created the Advanced Technology Program, the Technology Transfer Initiative, and the Technology Reinvestment Project, expanded the responsibilities of ARPA/DARPA, increased funding for the Small Business Initiative, expanded the Manufacturing Extension Partnership, funded SEMATECH, and increased NSF funding for basic research at universities. Many of these programs were later criticized for being industrial welfare and several were cut-back or stopped. Retrospective analysis shows that few of these programs addressed the root cause of competitiveness difficulties. In fact, by the time most of these programs were in place, US companies were well on their way to correcting their competitiveness problems. In addition, few were relevant to companies` often expressed concerns about workforce training, regulatory costs, and access to foreign markets. Twenty percent reductions in health care costs, regulatory costs, and education costs could annually pump $500 billion into the US economy and make companies operating in the US much more competitive in international markets.

  10. Successful Shared Governance Through Education.

    PubMed

    Brull, Stacey

    2015-01-01

    Shared governance is one way nurses can attain a healthy work environment. Having direct-care nurses involved in raising relevant clinical and operational issues and creating systematic approaches has been linked to greater levels of empowerment which is often transposed into shared governance. Nurse leaders at one hospital used a comprehensive educational strategy to implement shared governance in less than 2 years. An authoritative style of leadership and decision making does not meet the needs of today's complex health care environment; nor does it meet the needs of today's employees. The focus on a very deliberate and educational strategy for shared governance was successful in building the structures and processes needed to take a unit and division from traditional governance to shared governance in less than 2 years.

  11. Successful Shared Governance Through Education.

    PubMed

    Brull, Stacey

    2015-01-01

    Shared governance is one way nurses can attain a healthy work environment. Having direct-care nurses involved in raising relevant clinical and operational issues and creating systematic approaches has been linked to greater levels of empowerment which is often transposed into shared governance. Nurse leaders at one hospital used a comprehensive educational strategy to implement shared governance in less than 2 years. An authoritative style of leadership and decision making does not meet the needs of today's complex health care environment; nor does it meet the needs of today's employees. The focus on a very deliberate and educational strategy for shared governance was successful in building the structures and processes needed to take a unit and division from traditional governance to shared governance in less than 2 years. PMID:26845819

  12. Global health justice and governance.

    PubMed

    Ruger, Jennifer Prah

    2012-01-01

    While there is a growing body of work on moral issues and global governance in the fields of global justice and international relations, little work has connected principles of global health justice with those of global health governance for a theory of global health. Such a theory would enable analysis and evaluation of the current global health system and would ethically and empirically ground proposals for reforming it to more closely align with moral values. Global health governance has been framed as an issue of national security, human security, human rights, and global public goods. The global health governance literature is essentially untethered to a theorized framework to illuminate or evaluate governance. This article ties global health justice and ethics to principles for governing the global health realm, developing a theoretical framework for global and domestic institutions and actors.

  13. Global health justice and governance.

    PubMed

    Ruger, Jennifer Prah

    2012-01-01

    While there is a growing body of work on moral issues and global governance in the fields of global justice and international relations, little work has connected principles of global health justice with those of global health governance for a theory of global health. Such a theory would enable analysis and evaluation of the current global health system and would ethically and empirically ground proposals for reforming it to more closely align with moral values. Global health governance has been framed as an issue of national security, human security, human rights, and global public goods. The global health governance literature is essentially untethered to a theorized framework to illuminate or evaluate governance. This article ties global health justice and ethics to principles for governing the global health realm, developing a theoretical framework for global and domestic institutions and actors. PMID:23215931

  14. Kcna1 gene deletion lowers the behavioral sensitivity of mice to small changes in sound location and increases asynchronous brainstem auditory evoked potentials, but does not affect hearing thresholds

    PubMed Central

    Allen, Paul D.; Ison, James R.

    2012-01-01

    Sound localization along the azimuth depends on the sensitivity of binaural nuclei in the auditory brainstem to small differences in interaural level and timing occurring within a sub-millisecond epoch, and on monaural pathways that transmit level and timing cues with high temporal fidelity to insure their coincident arrival at the binaural targets. The soma and axons of these brainstem neurons are heavily invested with ion channels containing the low-threshold potassium channel subunit Kv1.1, which previous in-vitro and in-vivo studies suggest are important for regulating their high input-output correspondence and temporal synchrony. We compared awake Kcna1 null mutant (−/−) mice lacking Kv1.1 with +/+ mice to determine if Kv1.1 activity contributes to sound localization, and examined anesthetized mice for absolute hearing thresholds for suprathreshold differences that may be revealed in the waveforms of auditory brainstem response potentials. The awake −/− mice tested with reflex modification audiometry had reduced sensitivity to an abrupt change in the location of a broad band noise compared to +/+ mice, while anesthetized −/− mice had normal absolute thresholds for tone pips but a high level of stimulus-evoked but asynchronous background activity. Evoked potential waveforms had progressively earlier peaks and troughs in −/− mice but the amplitude excursions between adjacent features were identical in the two groups. Their greater excitability and asynchrony in suprathreshold evoked potentials coupled with their normal thresholds suggests that a disruption in central neural processing in −/− mice and not peripheral hearing loss is responsible for their poor sound localization. PMID:22396426

  15. Technology transfer within the government

    NASA Technical Reports Server (NTRS)

    Russell, John

    1992-01-01

    The report of a workshop panel concerned with technology transfer within the government is presented. The presentation is made in vugraph form. The assigned subtopic for this panel are as follows: (1) transfer from non-NASA US government technology developers to NASA space missions/programs; and (2) transfer from NASA to other US government space mission programs. A specific area of inquiry was Technology Maturation Milestones. Three areas were investigated: technology development; advanced development; and flight hardware development.

  16. 78 FR 23622 - National Small Business Development Center Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Small Business Development Center Advisory Board AGENCY: U.S. Small Business... National Small Business Development Center (SBDC) Advisory Board. DATES: The meetings for the 3rd...

  17. 76 FR 41320 - National Small Business Development Center Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Small Business Development Center Advisory Board AGENCY: U.S. Small Business... National Small Business Development Center (SBDC) Advisory Board. DATES: The meetings for the 4th...

  18. 41 CFR 109-40.110-1 - Small business assistance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases...

  19. 41 CFR 109-40.110-1 - Small business assistance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases...

  20. 76 FR 27935 - Small Business Size Standards: Transportation and Warehousing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Part 121 RIN 3245-AG08 Small Business Size Standards: Transportation and Warehousing AGENCY: U.S. Small Business Administration. ACTION: Proposed rule. SUMMARY: The U.S. Small...

  1. Government influence on patient organizations.

    PubMed

    Van de Bovenkamp, Hester M; Trappenburg, Margo J

    2011-12-01

    Patient organizations increasingly play an important role in health care decision-making in Western countries. The Netherlands is one of the countries where this trend has gone furthest. In the literature some problems are identified, such as instrumental use of patient organizations by care providers, health insurers and the pharmaceutical industry. To strengthen the position of patient organizations government funding is often recommended as a solution. In this paper we analyze the ties between Dutch government and Dutch patient organizations to learn more about the effects of such a relationship between government and this part of civil society. Our study is based on official government documents and existing empirical research on patient organizations. We found that government influence on patient organizations has become quite substantial with government influencing the organizational structure of patient organizations, the activities these organizations perform and even their ideology. Financing patient organizations offers the government an important means to hold them accountable. Although the ties between patient organizations and the government enable the former to play a role that can be valued as positive by both parties, we argue that they raise problems as well which warrant a discussion on how much government influence on civil society is acceptable.

  2. County Governments: "Forgotten" Subjects in Local Government Courses?

    ERIC Educational Resources Information Center

    Benton, J. Edwin

    2007-01-01

    Revenue, expenditure, and employment data indicate that county governments--once taken for granted and playing "second fiddle" to municipalities--are playing an increasingly important role (and sometimes a role equal to that of municipalities) as vital service providers. Therefore, one would expect that county governments and municipal governments…

  3. Government and Governance of Regional Triple Helix Interactions

    ERIC Educational Resources Information Center

    Danson, Mike; Todeva, Emanuela

    2016-01-01

    This conceptual paper contributes to the discussion of the role of regional government and regional Triple Helix constellations driving economic development and growth within regional boundaries. The impact of regionalism and subsidiarity on regional Triple Helix constellations, and the questions of governmentality, governance and institutional…

  4. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition

    PubMed Central

    2014-01-01

    Background Recent evidence indicates that long noncoding RNAs (lncRNAs) play a critical role in the regulation of cellular processes, such as differentiation, proliferation and metastasis. These lncRNAs are found to be dysregulated in a variety of cancers. BRAF activated non-coding RNA (BANCR) is a 693-bp transcript on chromosome 9 with a potential functional role in melanoma cell migration. The clinical significance of BANCR, and its’ molecular mechanisms controlling cancer cell migration and metastasis are unclear. Methods Expression of BANCR was analyzed in 113 non-small cell lung cancer (NSCLC) tissues and seven NSCLC cell lines using quantitative polymerase chain reaction (qPCR) assays. Gain and loss of function approaches were used to investigate the biological role of BANCR in NSCLC cells. The effects of BANCR on cell viability were evaluated by MTT and colony formation assays. Apoptosis was evaluated by Hoechst staining and flow cytometry. Nude mice were used to examine the effects of BANCR on tumor cell metastasis in vivo. Protein levels of BANCR targets were determined by western blotting and fluorescent immunohistochemistry. Results BANCR expression was significantly decreased in 113 NSCLC tumor tissues compared with normal tissues. Additionally, reduced BANCR expression was associated with larger tumor size, advanced pathological stage, metastasis distance, and shorter overall survival of NSCLC patients. Reduced BANCR expression was found to be an independent prognostic factor for NSCLC. Histone deacetylation was involved in the downregulation of BANCR in NSCLC cells. Ectopic expression of BANCR impaired cell viability and invasion, leading to the inhibition of metastasis in vitro and in vivo. However, knockdown of BANCR expression promoted cell migration and invasion in vitro. Overexpression of BANCR was found to play a key role in epithelial-mesenchymal transition (EMT) through the regulation of E-cadherin, N-cadherin and Vimentin expression

  5. 15 CFR Appendix A to Part 0 - Statutes Governing Conduct of Federal Employees

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... are referred to in this appendix. a. bribery and graft .01Title 18, U.S.C., section 201, prohibits... affecting the government .01Title 18, U.S.C., section 203, prohibits an officer or employee from receiving... officers and employees in claims against and other matters affecting the government .01Title 18,...

  6. 15 CFR Appendix A to Part 0 - Statutes Governing Conduct of Federal Employees

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... are referred to in this appendix. a. bribery and graft .01Title 18, U.S.C., section 201, prohibits... affecting the government .01Title 18, U.S.C., section 203, prohibits an officer or employee from receiving... officers and employees in claims against and other matters affecting the government .01Title 18,...

  7. 15 CFR Appendix A to Part 0 - Statutes Governing Conduct of Federal Employees

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... are referred to in this appendix. a. bribery and graft .01Title 18, U.S.C., section 201, prohibits... affecting the government .01Title 18, U.S.C., section 203, prohibits an officer or employee from receiving... officers and employees in claims against and other matters affecting the government .01Title 18,...

  8. 15 CFR Appendix A to Part 0 - Statutes Governing Conduct of Federal Employees

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... are referred to in this appendix. a. bribery and graft .01Title 18, U.S.C., section 201, prohibits... affecting the government .01Title 18, U.S.C., section 203, prohibits an officer or employee from receiving... officers and employees in claims against and other matters affecting the government .01Title 18,...

  9. 47 CFR 90.173 - Policies governing the assignment of frequencies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Federal Register citations affecting § 90.173, see the List of CFR Sections Affected, which appears in the... 47 Telecommunication 5 2012-10-01 2012-10-01 false Policies governing the assignment of... SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Policies Governing the Assignment of...

  10. 47 CFR 90.173 - Policies governing the assignment of frequencies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Federal Register citations affecting § 90.173, see the List of CFR Sections Affected, which appears in the... 47 Telecommunication 5 2014-10-01 2014-10-01 false Policies governing the assignment of... SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Policies Governing the Assignment of...

  11. 17 CFR 249.218 - Form 18, for foreign governments and political subdivisions thereof.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Federal Register citations affecting Form 18, see the List of CFR Sections Affected, which appears in the... governments and political subdivisions thereof. 249.218 Section 249.218 Commodity and Securities Exchanges..., for foreign governments and political subdivisions thereof. This form shall be used for...

  12. 17 CFR 249.218 - Form 18, for foreign governments and political subdivisions thereof.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Federal Register citations affecting Form 18, see the List of CFR Sections Affected, which appears in the... governments and political subdivisions thereof. 249.218 Section 249.218 Commodity and Securities Exchanges..., for foreign governments and political subdivisions thereof. This form shall be used for...

  13. 17 CFR 249.218 - Form 18, for foreign governments and political subdivisions thereof.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Federal Register citations affecting Form 18, see the List of CFR Sections Affected, which appears in the... governments and political subdivisions thereof. 249.218 Section 249.218 Commodity and Securities Exchanges..., for foreign governments and political subdivisions thereof. This form shall be used for...

  14. 17 CFR 249.218 - Form 18, for foreign governments and political subdivisions thereof.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Federal Register citations affecting Form 18, see the List of CFR Sections Affected, which appears in the... governments and political subdivisions thereof. 249.218 Section 249.218 Commodity and Securities Exchanges..., for foreign governments and political subdivisions thereof. This form shall be used for...

  15. 17 CFR 249.218 - Form 18, for foreign governments and political subdivisions thereof.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Federal Register citations affecting Form 18, see the List of CFR Sections Affected, which appears in the... governments and political subdivisions thereof. 249.218 Section 249.218 Commodity and Securities Exchanges..., for foreign governments and political subdivisions thereof. This form shall be used for...

  16. The Governance of Nuclear Technology

    SciTech Connect

    Vergino, E S; May, M

    2003-09-22

    Eisenhower's Atoms for Peace speech in 1953 is remembered for engaging the world, and the Soviet Union in particular, in a dialogue about arms control and the formulation of a nuclear regime in which national and international security concerns growing from this unprecedented emerging and frightening new weapons capability would be addressed while tapping the civilian promise of nuclear applications for the good of mankind. Out of it came a series of initiatives, leading fifteen years later to the NPT, intended to allow the growth and spread of the beneficial uses of nuclear know-how while constraining the incentives and capabilities for nuclear weapons. The last 50 years has seen a gradual spread in nations with nuclear weapons, other nations with nuclear knowledge and capabilities, and still others with nuclear weapon intentions. Still most nations of the world have forgone weapon development, most have signed and abided by the NPT, and some that have had programs or even weapons, have turned these capabilities off. Yet despite this experience, and despite a relatively successful record up to a few years ago, there is today a clear and generally recognized crisis in nuclear governance, a crisis that affects the future of all the cross-cutting civilian/security issues we have cited. The crux of this crisis is a lack of consensus among the major powers whose support of international efforts is necessary for effective governance of nuclear activities. The lack of consensus focuses on three challenges: what to do about non-compliance, what to do about non-adherence, and what to do about the possible leakage of nuclear materials and technologies to terrorist groups. Short of regaining consensus on the priority to be given to nuclear material and technology controls, it is unlikely that any international regime to control nuclear materials and technologies, let alone oversee a growth in the nuclear power sector, will be successful in the tough cases where it needs to

  17. Phentermine, sibutramine and affective disorders.

    PubMed

    An, Hoyoung; Sohn, Hyunjoo; Chung, Seockhoon

    2013-04-01

    A safe and effective way to control weight in patients with affective disorders is needed, and phentermine is a possible candidate. We performed a PubMed search of articles pertaining to phentermine, sibutramine, and affective disorders. We compared the studies of phentermine with those of sibutramine. The search yielded a small number of reports. Reports concerning phentermine and affective disorders reported that i) its potency in the central nervous system may be comparatively low, and ii) it may induce depression in some patients. We were unable to find more studies on the subject; thus, it is unclear presently whether phentermine use is safe in affective disorder patients. Reports regarding the association of sibutramine and affective disorders were slightly more abundant. A recent study that suggested that sibutramine may have deleterious effects in patients with a psychiatric history may provide a clue for future phentermine research. Three explanations are possible concerning the association between phentermine and affective disorders: i) phentermine, like sibutramine, may have a depression-inducing effect that affects a specific subgroup of patients, ii) phentermine may have a dose-dependent depression-inducing effect, or iii) phentermine may simply not be associated with depression. Large-scale studies with affective disorder patients focusing on these questions are needed to clarify this matter before investigation of its efficacy may be carried out and it can be used in patients with affective disorders. PMID:23678348

  18. The Business of Governing Schools

    ERIC Educational Resources Information Center

    Gann, Nigel

    2015-01-01

    In September 2015, the Secretary of State for Education asked for more business involvement in schools, and in particular for business leaders' help to improve failing schools. This article questions the twenty-year campaign by all governments to engage business expertise and values in the governance of schools.

  19. Government Documents Departmental Operations Guide.

    ERIC Educational Resources Information Center

    Wilson, John S.; And Others

    This manual for the operation and maintenance of the Government Documents Department at Baylor University's Moody Memorial Library is divided into 13 topical sections. The guide opens with the collection development policy statement, which covers the general collection, the maps division, and weeding government documents. Technical processing…

  20. From Partnership to Community Governance

    ERIC Educational Resources Information Center

    Ranson, Stewart

    2010-01-01

    If learning is a journey between worlds, school governing bodies have a crucial role to play in mediating them. By establishing a public space for the voice of different communities to be expressed and deliberated governing bodies enable schools to understand and engage the cultural sources that motivate young people to learn. This article draws…

  1. Government Censorship and Academic Freedom.

    ERIC Educational Resources Information Center

    Rosenbaum, Robert A.; And Others

    1983-01-01

    This third report in a series concerning restraints by government agencies on academic research concerns and recommends withdrawal of a recent presidential directive establishing a mechanism for controlling the release of classified information to the public through a system of prior review by government officials. (MSE)

  2. School Boards: Emerging Governance Challenges

    ERIC Educational Resources Information Center

    Bradshaw, Patricia; Osborne, Rachel

    2010-01-01

    The governance role of school boards is not new. Local school boards have governed education in Canada since the 19th century. However, significant forces are impacting on school boards and how they enact their roles and responsibilities. In this article, the authors want to look at the growing pressures on school boards, to actively acknowledge…

  3. Governance: A Community College Model.

    ERIC Educational Resources Information Center

    Carhart, John I.; Collins, Charles C.

    The purpose of this report is to describe the development of the input/output governance model at Los Medanos College and to explore the governance issues pertinent to all community colleges. Considerations in creating the model included the issue of authority and responsibility in terms of legal sources, the authority and accountability…

  4. Recent Literature on Government Information

    ERIC Educational Resources Information Center

    Sleeman, Bill

    2004-01-01

    The purpose of this column is to provide government information scholars and students with a broad overview of recent publications about government information from the literature of librarianship, archives, information technology management, public policy and law. Given the volume of literature produced in this field, a columnist cannot claim…

  5. Recent Literature on Government Information

    ERIC Educational Resources Information Center

    Sleeman, Bill

    2004-01-01

    The purpose of this column is to provide government information scholars and students with a broad overview of recent publications about government information from the literature of librarianship, archives, information technology management, public policy, and law. Given the volume of literature produced in this field, a columnist cannot claim…

  6. State Governance Action Report, 2009

    ERIC Educational Resources Information Center

    Toutsi, Cristin

    2009-01-01

    This sixth edition of the State Governance Report summarizes the most relevant issues, legislative proposals, and proposed policies facing public higher education and its governance and oversight. The majority of coverage is devoted to the current or just recently completed 2009 legislative sessions. Other issues covered in this report include…

  7. Transforming Institutions through Shared Governance

    ERIC Educational Resources Information Center

    Bornstein, Rita

    2012-01-01

    Shared governance is a basic tenet of higher education and is frequently referred to. For shared governance to be successful, board members, administrators, and faculty members must learn to have respect for and confidence in each other, acting inclusively, transparently, and responsibly. Boards need to be active and involved, participating in…

  8. State and Local Government Purchasing.

    ERIC Educational Resources Information Center

    Council of State Governments, Lexington, KY.

    This report concerns public purchasing at all levels of government and brings into focus the role of the purchasing official in government management. Covered in the report are essential elements of the purchasing process, including the assessment of needs; written specifications; advertising, evaluating, and awarding bids; and inspection and…

  9. Government Policy, Saving and Investment.

    ERIC Educational Resources Information Center

    Eisner, Robert

    1983-01-01

    Several arguments that government policy--income redistribution and support of the poor, higher marginal income taxes, and social security--has depressed saving are found wanting. Also hard to sustain is the argument that investment demand has been depressed by tax policy. Current government policy will not improve saving and investment. (RM)

  10. The Future of Shared Governance

    ERIC Educational Resources Information Center

    Crellin, Matthew A.

    2010-01-01

    Higher education has relied on the power of collaborative decision making on college and university campuses through the model of shared governance since the early 1900s. However, the principles of shared governance are now more thoroughly tested than ever before. In response to these simultaneous pressures and challenges, the leadership of…

  11. Government Publishing: Past to Present.

    ERIC Educational Resources Information Center

    Hernon, Peter; Relyea, Harold C.

    1995-01-01

    Provides an overview of government publishing that focuses on the United States national government. Documents the shift from paper to electronic publication and discusses implications. Highlights include public availability and access, propaganda, policy, workshops on information dissemination, preservation of electronic resources, and the…

  12. Evaluation in the Government Marketplace.

    ERIC Educational Resources Information Center

    House, Ernest R.

    1997-01-01

    The large government market in evaluation that has developed in recent years does not follow the idealized image of open markets because of the contracting process, which means that a few firms conduct most evaluations. To produce honest, unbiased evaluations, evaluation ethics must take government market factors into consideration. (SLD)

  13. 3 CFR - Managing Government Records

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... records, including email and social media, deploying cloud-based services or storage solutions, and... 3 The President 1 2012-01-01 2012-01-01 false Managing Government Records Presidential Documents Other Presidential Documents Memorandum of November 28, 2011 Managing Government Records Memorandum...

  14. Understanding Horizontal Governance. Research Brief

    ERIC Educational Resources Information Center

    Ferguson, Daniel

    2009-01-01

    Horizontal governance is an umbrella term that covers a range of approaches to policy development, service delivery issues, and management practices. A horizontal initiative may take place across levels of government, across boundaries between units of a single department or agency or among multiple departments or agencies, or across public,…

  15. Faculty Communication with Governing Boards

    ERIC Educational Resources Information Center

    Tiede, Hans-Joerg

    2013-01-01

    College and university governance works best when every constituency within the institution has a clear understanding of its role with respect to the other constituencies. It works best when communication among the governing board, the administration, and the faculty (not to mention the staff and students) is regular, open, and honest. Too often…

  16. Governance matters: an ecological association between governance and child mortality

    PubMed Central

    Lin, Ro-Ting; Chien, Lung-Chang; Chen, Ya-Mei; Chan, Chang-Chuan

    2014-01-01

    Background Governance of a country may have widespread effects on the health of its population, yet little is known about the effect of governance on child mortality in a country that is undergoing urbanization, economic development, and disease control. Methods We obtained indicators of six dimensions of governance (perceptions of voice and accountability, political stability and absence of violence, government effectiveness, regulatory quality, rule of law, and control of corruption) and national under-5 mortality rates for 149 countries between 1996 and 2010. We applied a semi-parametric generalized additive mixed model to examine associations after controlling for the effects of development factors (urbanization level and economy), disease control factors (hygienic conditions and vaccination rates), health expenditures, air quality, and time. Results Governance, development, and disease control showed clear inverse relations with the under-5 mortality rate (p<0.001). Per unit increases in governance, development, and disease control factors, the child mortality rate had a 0.901-, 0.823-, and 0.922-fold decrease, respectively, at fixed levels of the other two factors. Conclusions In the effort to reduce the global under-5 mortality rate, addressing a country's need for better governance is as important as improvements in development and disease control. PMID:24711600

  17. English obesity policies: To govern and not to govern.

    PubMed

    Vallgårda, Signild

    2015-06-01

    Problem definitions constitute a crucial part of the policy process. In 2008 the Labour Government presented a plan to reduce the obesity prevalence in England. Only three years later the Conservative-Liberal Government introduced a plan on the same topic, which it presented as new and innovative. The aim of this study is to analyse the respective governments' problematisations of obesity and to identify similarities and differences. Despite the different hues of the two governments, the programmes are surprisingly similar. They seek to simultaneously govern and not to govern. They adhere to liberal ideals of individual choice and they also suggest initiatives that will lead people to choose certain behaviours. Both governments encourage the food and drink industry to support their policies voluntarily, rather than obliging them to do so, although Labour is somewhat more inclined to use statutory measures. The Conservative-Liberal plan does not represent many new ideas. The plans are characterised by the paradox that they convey both ideas and ideals about freedom of choice as well as about state interventions to influence people's choices, which could be seen as incompatible, but as the study shows in practice they are not.

  18. 78 FR 20371 - Small Business Size Standards; Waiver of the Nonmanufacturer Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ..., Associate Director for Government Contracting, U.S. Small Business Administration, 409 3rd Street SW., 8th... Government Contracting, U.S. Small Business Administration, 409 3rd Street SW., 8th Floor, Washington, DC... contract or received a contract from the Federal government within the last 24 months. See (13 CFR...

  19. Governance and Institutional Autonomy: Governing and Governance in Portuguese Higher Education

    ERIC Educational Resources Information Center

    Magalhaes, Antonio; Veiga, Amelia; Ribeiro, Filipa; Amaral, Alberto

    2013-01-01

    This paper aims at looking at governance instruments beyond managerial technicality. It intends to do so by analysing the impact of governance reforms on the universities autonomy assumed as a regulation instrument to politically steer systems and institutions. The regulation efforts undertaken at the European and national levels reflect a trend…

  20. 76 FR 35912 - Business Jet Aircraft Industry: Structure and Factors Affecting Competitiveness; Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ..., and business innovation; 4. Information on government policies and programs that focus on or otherwise involve the industry, including policies and programs affecting financing, aircraft research and... From the Federal Register Online via the Government Publishing Office INTERNATIONAL...

  1. Government Services Information Infrastructure Management

    SciTech Connect

    Cavallini, J.S.; Aiken, R.J.

    1995-04-01

    The Government Services Information Infrastructure (GSII) is that portion of the NII used to link Government and its services, enables virtual agency concepts, protects privacy, and supports emergency preparedness needs. The GSII is comprised of the supporting telecommunications technologies, network and information services infrastructure and the applications that use these. The GSII is an enlightened attempt by the Clinton/Gore Administration to form a virtual government crossing agency boundaries to interoperate more closely with industry and with the public to greatly improve the delivery of government services. The GSII and other private sector efforts, will have a significant impact on the design, development, and deployment of the NII, even if only through the procurement of such services. The Federal Government must adopt new mechanisms and new paradigms for the management of the GSII, including improved acquisition and operation of GSII components in order to maximize benefits. Government requirements and applications will continue to evolv. The requirements from government services and users of form affinity groups that more accurately and effectively define these common requirements, that drive the adoption and use of industry standards, and that provide a significant technology marketplace.

  2. Federal research assessment of small business innovation research programs

    SciTech Connect

    Not Available

    1989-01-01

    Since 1983, federal agencies with large research and development budgets have operated Small Business Innovation Research (SBIR) programs to strengthen the role of small innovative firms in federally supported research and development. SBIR awards to small business have totaled over $1.35 billion through fiscal year 1988. In reauthorizing SBIR programs in 1986, the Congress directed GAO to study their effectiveness in meeting SBIR goals, which are to (1) stimulate technological innovation, (2) use small businesses to meet federal research and development needs, (3) increase private sector commercialization of innovations from federal research and development, and (4) encourage participation by minority and disadvantaged firms in technological innovation. The Congress also directed GAO to compare the quality of SBIR research with more traditional agency research and to obtain the views of agency and department heads on how SBIR programs have affected other research activities at their agencies. To obtain information on how well SBIR programs are meeting their goals and on the quality of research, GAO sent questionnaires to firms with SBIR projects and to government project officers responsible for SBIR and other research.

  3. Benign small bowel tumor.

    PubMed Central

    Wilson, J M; Melvin, D B; Gray, G; Thorbjarnarson, B

    1975-01-01

    The clinical record and histologic sections of 84 cases of benign small bowel tumor are reviewed. Manifestations of systemic diseases, congenital anomalies, and lesions of either the ileocecal valve or periampullary region were excluded. In the same time span there were 96 small bowel malignancies. Clinical presentation, pathologic findings, management and result are compared to the collected published experience of about 2000 cases. There were 36 leiomyomas, 22 lipomas, 9 angiomas, 6 neurofibromas and 4 fibromas. Thirty-six men and 48 women were affected; the majority in their fifth and sixth decade. Seventy-eight were operative and 6 autopsy diagnoses. The most common symptom was obstruction (42%) followed by hemorrhage (34%) and pain (22%), relative frequency differing for the various specific tumors. There were rarely significant physical findings. A diagnosis of small bowel tumor was made radiologically in 30 patients. Because of the nonspecificity of other signs and symptoms, an acute awareness of the possibility of small bowel tumor is mandatory for preoperative anticipation of the diagnosis. Local resection was performed in all with no deaths or significant postoperative complications. PMID:1078626

  4. Adaptive governance to promote ecosystem services in urban green spaces

    EPA Science Inventory

    Managing urban green space as part of an ongoing social-ecological transformationposes novel governance issues, particularly in post-industrial settings. Urban green spaces operate as small-scale nodes in larger networks of ecological reserves that provide and maintain key ecosys...

  5. Governing for the Common Good.

    PubMed

    Ruger, Jennifer Prah

    2015-12-01

    The proper object of global health governance (GHG) should be the common good, ensuring that all people have the opportunity to flourish. A well-organized global society that promotes the common good is to everyone's advantage. Enabling people to flourish includes enabling their ability to be healthy. Thus, we must assess health governance by its effectiveness in enhancing health capabilities. Current GHG fails to support human flourishing, diminishes health capabilities and thus does not serve the common good. The provincial globalism theory of health governance proposes a Global Health Constitution and an accompanying Global Institute of Health and Medicine that together propose to transform health governance. Multiple lines of empirical research suggest that these institutions would be effective, offering the most promising path to a healthier, more just world.

  6. Government Reform Act of 2011

    THOMAS, 112th Congress

    Rep. Royce, Edward R. [R-CA-40

    2011-01-05

    02/08/2011 Referred to the Subcommittee on Government Organization, Efficiency, and Financial Management . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  7. New government raises science hopes

    NASA Astrophysics Data System (ADS)

    Gwynne, Peter

    2015-12-01

    Canada's scientific community has welcomed the country's new Liberal government - led by prime minister Justin Trudeau - after it promised to put science on a stronger footing than in the previous decade of Conservative rule.

  8. Governing for the Common Good.

    PubMed

    Ruger, Jennifer Prah

    2015-12-01

    The proper object of global health governance (GHG) should be the common good, ensuring that all people have the opportunity to flourish. A well-organized global society that promotes the common good is to everyone's advantage. Enabling people to flourish includes enabling their ability to be healthy. Thus, we must assess health governance by its effectiveness in enhancing health capabilities. Current GHG fails to support human flourishing, diminishes health capabilities and thus does not serve the common good. The provincial globalism theory of health governance proposes a Global Health Constitution and an accompanying Global Institute of Health and Medicine that together propose to transform health governance. Multiple lines of empirical research suggest that these institutions would be effective, offering the most promising path to a healthier, more just world. PMID:26122555

  9. Government Neutrality in Contracting Act

    THOMAS, 111th Congress

    Rep. Sullivan, John [R-OK-1

    2009-02-11

    02/24/2009 Referred to the Subcommittee on Government Management, Organization, and Procurement. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  10. Student Perceptions of Small-Group Learning

    ERIC Educational Resources Information Center

    Florez, Ida Rose; McCaslin, Mary

    2008-01-01

    Background/Context: Elementary school teachers regularly arrange students in small groups for learning activities. A rich literature discusses various types of small-group learning formats and how those formats affect achievement. Few studies, however, have examined students' perceptions of small-group learning experiences. Our work extends the…

  11. 48 CFR 225.7303-3 - Government-to-government agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Government-to-government... Military Sales 225.7303-3 Government-to-government agreements. If a government-to-government agreement between the United States and a foreign government for the sale, coproduction, or cooperative...

  12. 48 CFR 225.7303-3 - Government-to-government agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Government-to-government... Military Sales 225.7303-3 Government-to-government agreements. If a government-to-government agreement between the United States and a foreign government for the sale, coproduction, or cooperative...

  13. 48 CFR 225.7303-3 - Government-to-government agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Government-to-government... Military Sales 225.7303-3 Government-to-government agreements. If a government-to-government agreement between the United States and a foreign government for the sale, coproduction, or cooperative...

  14. Global standards and local knowledge building: Upgrading small producers in developing countries

    PubMed Central

    Perez-Aleman, Paola

    2012-01-01

    Local knowledge building is a crucial factor for upgrading small producers and improving their market competitiveness and livelihoods. The rise of global standards affecting food safety and environmental sustainability in agriculture sparks debates on the impact on smallholders in developing countries. This article presents a perspective on the links of international standards to knowledge and institution building for developing the capabilities of small producers. Interacting with global practices, indigenous private and public actors create local institutions to develop capabilities for product and process innovations that contribute to economic development and enhance food security. Local innovation depends on collective strategic efforts through increasing networks among small producers and other organizations, including firms, nongovernmental organizations, and government, that foster knowledge circulation and bring diverse resources and support to build local capabilities. PMID:21670309

  15. Governance, Government, and the Search for New Provider Models.

    PubMed

    Saltman, Richard B; Duran, Antonio

    2016-01-01

    A central problem in designing effective models of provider governance in health systems has been to ensure an appropriate balance between the concerns of public sector and/or government decision-makers, on the one hand, and of non-governmental health services actors in civil society and private life, on the other. In tax-funded European health systems up to the 1980s, the state and other public sector decision-makers played a dominant role over health service provision, typically operating hospitals through national or regional governments on a command-and-control basis. In a number of countries, however, this state role has started to change, with governments first stepping out of direct service provision and now de facto pushed to focus more on steering provider organizations rather than on direct public management. In this new approach to provider governance, the state has pulled back into a regulatory role that introduces market-like incentives and management structures, which then apply to both public and private sector providers alike. This article examines some of the main operational complexities in implementing this new governance reality/strategy, specifically from a service provision (as opposed to mostly a financing or even regulatory) perspective. After briefly reviewing some of the key theoretical dilemmas, the paper presents two case studies where this new approach was put into practice: primary care in Sweden and hospitals in Spain. The article concludes that good governance today needs to reflect practical operational realities if it is to have the desired effect on health sector reform outcome. PMID:26673647

  16. Governance, Government, and the Search for New Provider Models.

    PubMed

    Saltman, Richard B; Duran, Antonio

    2015-11-03

    A central problem in designing effective models of provider governance in health systems has been to ensure an appropriate balance between the concerns of public sector and/or government decision-makers, on the one hand, and of non-governmental health services actors in civil society and private life, on the other. In tax-funded European health systems up to the 1980s, the state and other public sector decision-makers played a dominant role over health service provision, typically operating hospitals through national or regional governments on a command-and-control basis. In a number of countries, however, this state role has started to change, with governments first stepping out of direct service provision and now de facto pushed to focus more on steering provider organizations rather than on direct public management. In this new approach to provider governance, the state has pulled back into a regulatory role that introduces market-like incentives and management structures, which then apply to both public and private sector providers alike. This article examines some of the main operational complexities in implementing this new governance reality/strategy, specifically from a service provision (as opposed to mostly a financing or even regulatory) perspective. After briefly reviewing some of the key theoretical dilemmas, the paper presents two case studies where this new approach was put into practice: primary care in Sweden and hospitals in Spain. The article concludes that good governance today needs to reflect practical operational realities if it is to have the desired effect on health sector reform outcome.

  17. Governance, Government, and the Search for New Provider Models

    PubMed Central

    Saltman, Richard B.; Duran, Antonio

    2016-01-01

    A central problem in designing effective models of provider governance in health systems has been to ensure an appropriate balance between the concerns of public sector and/or government decision-makers, on the one hand, and of non-governmental health services actors in civil society and private life, on the other. In tax-funded European health systems up to the 1980s, the state and other public sector decision-makers played a dominant role over health service provision, typically operating hospitals through national or regional governments on a command-and-control basis. In a number of countries, however, this state role has started to change, with governments first stepping out of direct service provision and now de facto pushed to focus more on steering provider organizations rather than on direct public management. In this new approach to provider governance, the state has pulled back into a regulatory role that introduces market-like incentives and management structures, which then apply to both public and private sector providers alike. This article examines some of the main operational complexities in implementing this new governance reality/strategy, specifically from a service provision (as opposed to mostly a financing or even regulatory) perspective. After briefly reviewing some of the key theoretical dilemmas, the paper presents two case studies where this new approach was put into practice: primary care in Sweden and hospitals in Spain. The article concludes that good governance today needs to reflect practical operational realities if it is to have the desired effect on health sector reform outcome. PMID:26673647

  18. A novel family of small proteins that affect plant development

    SciTech Connect

    John Charles Walker

    2011-04-29

    The DVL genes represent a new group of plant proteins that influence plant growth and development. Overexpression of DVL1, and other members of the DVL family, causes striking phenotypic changes. The DVL proteins share sequence homology in their C-terminal half. Point mutations in the C-terminal domain show it is necessary and deletion studies demonstrate the C-terminal domain is sufficient to confer the overexpression phenotypes. The phenotypes observed, and the conservation of the protein sequence in the plant kingdom, does suggest the DVL proteins have a role in modulating plant growth and development. Our working hypothesis is the DVL proteins function as regulators of cellular signaling pathways that control growth and development.

  19. Developing Government Renewable Energy Projects

    SciTech Connect

    Kurt S. Myers; Thomas L. Baldwin; Jason W. Bush; Jake P. Gentle

    2012-07-01

    The US Army Corps of Engineers has retained Idaho National Laboratory (INL) to conduct a study of past INL experiences and complete a report that identifies the processes that are needed for the development of renewable energy projects on government properties. The INL has always maintained expertise in power systems and applied engineering and INL’s renewable energy experiences date back to the 1980’s when our engineers began performing US Air Force wind energy feasibility studies and development projects. Over the last 20+ years of working with Department of Defense and other government agencies to study, design, and build government renewable projects, INL has experienced the do’s and don’ts for being successful with a project. These compiled guidelines for government renewable energy projects could include wind, hydro, geothermal, solar, biomass, or a variety of hybrid systems; however, for the purpose of narrowing the focus of this report, wind projects are the main topic discussed throughout this report. It is our thought that a lot of what is discussed could be applied, possibly with some modifications, to other areas of renewable energy. It is also important to note that individual projects (regardless the type) vary to some degree depending on location, size, and need but in general these concepts and directions can be carried over to the majority of government renewable energy projects. This report focuses on the initial development that needs to occur for any project to be a successful government renewable energy project.

  20. Blaming the Government for Environmental Problems: A Multilevel and Cross-National Analysis of the Relationship between Trust in Government and Local and Global Environmental Concerns

    ERIC Educational Resources Information Center

    Cin, Cigdem Kentmen

    2013-01-01

    Although the determinants of trust in governments have received significant attention in the literature on political trust, there has been no attention paid to whether environmental concerns affect governmental trust. Yet, if individuals are worried about local and global environmental degradation, they may think that the government has failed in…

  1. Policies Affecting New York City's Low-Income Families.

    ERIC Educational Resources Information Center

    O'Neill, Hugh; Garcia, Kathryn; Amerlynck, Virginie; Blum, Barbara

    This report describes policy and program changes affecting New York's low-income families, issues related to these changes, and ways that city, state, and federal governments might further enhance the well-being of low-income families. Part 1 reviews major new policies enacted by the federal and state governments since the mid-1990s, noting how…

  2. 48 CFR 46.406 - Foreign governments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Foreign governments. 46... MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 46.406 Foreign governments. Government contract quality assurance performed for foreign governments or international agencies shall...

  3. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or...

  4. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or...

  5. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or...

  6. 48 CFR 46.406 - Foreign governments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Foreign governments. 46... MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 46.406 Foreign governments. Government contract quality assurance performed for foreign governments or international agencies shall...

  7. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or...

  8. 48 CFR 46.406 - Foreign governments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Foreign governments. 46... MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 46.406 Foreign governments. Government contract quality assurance performed for foreign governments or international agencies shall...

  9. 48 CFR 46.406 - Foreign governments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Foreign governments. 46... MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 46.406 Foreign governments. Government contract quality assurance performed for foreign governments or international agencies shall...

  10. 48 CFR 46.406 - Foreign governments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Foreign governments. 46... MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 46.406 Foreign governments. Government contract quality assurance performed for foreign governments or international agencies shall...

  11. 42 CFR 425.106 - Shared governance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Shared governance. 425.106 Section 425.106 Public... Requirements § 425.106 Shared governance. (a) General rule. An ACO must maintain an identifiable governing body... innovative ways in ACO governance or provide meaningful representation in ACO governance by...

  12. 42 CFR 425.106 - Shared governance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Shared governance. 425.106 Section 425.106 Public... Requirements § 425.106 Shared governance. (a) General rule. An ACO must maintain an identifiable governing body... innovative ways in ACO governance or provide meaningful representation in ACO governance by...

  13. 42 CFR 425.106 - Shared governance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Shared governance. 425.106 Section 425.106 Public... Requirements § 425.106 Shared governance. (a) General rule. An ACO must maintain an identifiable governing body... innovative ways in ACO governance or provide meaningful representation in ACO governance by...

  14. The Assembly on University Goals and Governance. A First Report.

    ERIC Educational Resources Information Center

    American Academy of Arts and Sciences, Boston, MA.

    The Assembly on University Goals and Governance was established by the American Academy of Arts and Sciences in September 1969 to explore, develop, and help implement alternative approaches for resolving certain of the issues affecting colleges and universities today. This report presents the 85 theses that were developed by the Assembly. The…

  15. Changing School Board Governance in Primary Education through School Inspections

    ERIC Educational Resources Information Center

    Ehren, Melanie C. M.; Honingh, M. E.; Hooge, E. H.; O'Hara, J.

    2016-01-01

    This paper addresses if, and to what extent, the current working methods of the Dutch Inspectorate of Education affect the governance of school boards in schools for primary education. A key facet of the working method is the inspection meeting with the school board. Drawing upon a large quantitative study (n = 244) we are able to identify some…

  16. Practicing What We Preach: Cultivating Democratic Practice in Governance

    ERIC Educational Resources Information Center

    Kezar, Adrianna; Hartley, Matthew; Maxey, Daniel

    2012-01-01

    In this article, the authors explain why examining the way institutions model democracy on campus is an important, but often overlooked, step in advancing students' democratic learning. First, they note how a decline in shared governance produces an educational environment that adversely affects students' civic inclinations and agency. Next, they…

  17. Small taxes on soft drinks and snack foods to promote health.

    PubMed Central

    Jacobson, M F; Brownell, K D

    2000-01-01

    Health officials often wish to sponsor nutrition and other health promotion programs but are hampered by lack of funding. One source of funding is suggested by the fact that 18 states and 1 major city levy special taxes on soft drinks, candy, chewing gum, or snack foods. The tax rates may be too small to affect sales, but in some jurisdictions, the revenues generated are substantial. Nationally, about $1 billion is raised annually from these taxes. The authors propose that state and local governments levy taxes on foods of low nutritional value and use the revenues to fund health promotion programs. PMID:10846500

  18. Human capital management in government: replacing government retirees.

    PubMed

    Kochanowski, Yvonne J

    2011-01-01

    Faced with high levels of senior civil servant retirement in the coming years and limited by civil service requirements, government organizations often struggle to maintain the knowledge base of previous processes and results while promoting people who are truly interested in being leaders in an agency. Upcoming generations of public sector workers do not share the same motivation and workplace characteristics of current exiting civil servants, further complicating smooth transitions of leadership. Government personnel systems for the most part are inflexible and slow to hire, and retention methods for workers do not encourage succession planning. Against this backdrop, a five-phased human capital management system, using some of the best practices found in both public and private sector organizations, is proposed as a solution for replacing government retirees with workers who are prepared for their leadership and management roles.

  19. 75 FR 22499 - Establishing an Interagency Task Force on Federal Contracting Opportunities for Small Businesses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ...-disabled veterans, have fair access to Federal Government contracting. Indeed, where small businesses have...' efforts towards ensuring that all small businesses have a fair chance to participate in Federal... accurate data on the Federal Government's progress in ensuring that all small businesses have a fair...

  20. 37 CFR 401.7 - Small business preference.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph...

  1. 37 CFR 401.7 - Small business preference.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph...

  2. 48 CFR 719.270 - Small business policies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... 719.270 Section 719.270 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.270 Small business policies. (a) In keeping with... Government's small business program for placing a fair proportion of its purchases and contracts for...

  3. 76 FR 62313 - Small Business Size and Status Integrity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Parts 121, 124, 125, 126, 127 RIN 3245-AG23 Small Business Size and Status Integrity AGENCY... identified as a small disadvantaged business concern in the Online Representations and...

  4. 37 CFR 401.7 - Small business preference.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Small business preference... GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k)(4) of the clauses at § 401.14 Implements the small business preference requirement of 35 U.S.C....

  5. Government action to reduce smoking.

    PubMed

    Sandford, Amanda

    2003-03-01

    The major health impacts of smoking were established more than 40 years ago but Governments were slow to respond to the growing health epidemic. Despite laudable tobacco control strategies in many countries, globally deaths from smoking continue to rise and are forecast to reach 10 million a year by the 2030's. There is now general agreement that in order to substantially reduce smoking rates, governments need to adopt a comprehensive approach to tobacco control. This should include a range of measures, notably: a total ban on tobacco advertising and promotion; restrictions on smoking in public places and in the workplace; sustained increases in tobacco taxation combined with measures to curb smuggling; large, bold health warnings on tobacco products; smoking cessation and health education campaigns; and the regulation of tobacco to standards agreed by the health community rather than those set by the tobacco industry. While legislation is to be favoured over voluntary controls, the key to the successful implementation of these measures is winning public support and ensuring proper enforcement. Given the enormous burden that smoking places on health services, governments in developed nations have generally responded by introducing a range of tobacco control measures. However, the picture is far from uniform and some of the best examples of strong, government-led action have occurred in less developed nations. Governments can learn much from these countries and, by supporting the impending global treaty on tobacco control, can help to reduce the smoking-related diseases and deaths of the future.

  6. Earthquake Planning for Government Continuity

    PubMed

    PERRY; LINDELL

    1997-01-01

    / The problem of assuring government operational continuity following earthquakes has been given little research attention. Recent earthquake experience has documented that government organizations without a public safety mission do incur damaged facilities and routinely see increases in public demands following an earthquake. Impediments to service delivery associated with such dam-ages can be minimized if agencies address earthquake plan elements likely to enhance postimpact functioning, including: the potential to relocate operations, protection for the workplace, possession of an organizational inventory, emergency instructions for employees, the ability to use volunteers, and communication capacity. Factors associated with the adoption of these plan elements were studied in one county government and its municipal county seat in the southwestern United States. A census of departments within these jurisdictions was asked to complete a questionnaire reporting the level of planning activity relative to each of these plan elements. It was found that the overall level of preparedness was low, but statistically significantly related to agency size, perceived risk, and information seeking. The implications of these findings underscore the potential for disruption to government service delivery and permit the identification of potential avenues for increasing levels of preparedness.KEY WORDS: Emergency planning; Earthquakes; Government preparedness PMID:8939788

  7. Space Station Facility government estimating

    NASA Technical Reports Server (NTRS)

    Brown, Joseph A.

    1993-01-01

    This new, unique Cost Engineering Report introduces the 800-page, C-100 government estimate for the Space Station Processing Facility (SSPF) and Volume IV Aerospace Construction Price Book. At the January 23, 1991, bid opening for the SSPF, the government cost estimate was right on target. Metric, Inc., Prime Contractor, low bid was 1.2 percent below the government estimate. This project contains many different and complex systems. Volume IV is a summary of the cost associated with construction, activation and Ground Support Equipment (GSE) design, estimating, fabrication, installation, testing, termination, and verification of this project. Included are 13 reasons the government estimate was so accurate; abstract of bids, for 8 bidders and government estimate with additive alternates, special labor and materials, budget comparison and system summaries; and comments on the energy credit from local electrical utility. This report adds another project to our continuing study of 'How Does the Low Bidder Get Low and Make Money?' which was started in 1967, and first published in the 1973 AACE Transaction with 18 ways the low bidders get low. The accuracy of this estimate proves the benefits of our Kennedy Space Center (KSC) teamwork efforts and KSC Cost Engineer Tools which are contributing toward our goals of the Space Station.

  8. Analytical fuel property effects--small combustors

    NASA Technical Reports Server (NTRS)

    Sutton, R. D.; Troth, D. L.; Miles, G. A.

    1984-01-01

    The consequences of using broad-property fuels in both conventional and advanced state-of-the-art small gas turbine combustors are assessed. Eight combustor concepts were selected for initial screening, of these, four final combustor concepts were chosen for further detailed analysis. These included the dual orifice injector baseline combustor (a current production 250-C30 engine combustor) two baseline airblast injected modifications, short and piloted prechamber combustors, and an advanced airblast injected, variable geometry air staged combustor. Final predictions employed the use of the STAC-I computer code. This quasi 2-D model includes real fuel properties, effects of injector type on atomization, detailed droplet dynamics, and multistep chemical kinetics. In general, fuel property effects on various combustor concepts can be classified as chemical or physical in nature. Predictions indicate that fuel chemistry has a significant effect on flame radiation, liner wall temperature, and smoke emission. Fuel physical properties that govern atomization quality and evaporation rates are predicted to affect ignition and lean-blowout limits, combustion efficiency, unburned hydrocarbon, and carbon monoxide emissions.

  9. New directions in hospital governance.

    PubMed

    Shortell, S M

    1989-01-01

    This article suggests new directions for hospital governance to meet the demands of a rapidly changing health care environment. Board members must increasingly play roles as risk takers, strategic directors, experts, mentors, and evaluators. Lessons from other industries regarding risk taking, use of expertise, and streamlining decision making must be adapted to meet hospital needs. Recent data suggest that these needs may still differ by hospital ownership despite a convergence in investor-owned and not-for-profit corporate structures. The effectiveness of hospital boards in the future will depend on their ability to: (1) manage a diverse group of stakeholders; (2) involve physicians in the management and governance process; (3) meet the governance needs of multi-institutional systems and hospital restructuring; (4) meet the challenges of diversification and vertical integration; and (5) understand strategy formulation and implementation as interdependent and interrelated processes.

  10. Technology transfer within the government

    NASA Technical Reports Server (NTRS)

    Christensen, Carissa Bryce

    1992-01-01

    The report of a workshop panel concerned with technology transfer within the government is presented. The suggested subtopics for the panel were as follows: (1) transfer from non-NASA U.S. government technology developers to NASA space missions/programs; and (2) transfer from NASA to other U.S. government civil space mission programs. Two presentations were made to the panel: Roles/Value of Early Strategic Planning Within the Space Exploration Initiative (SEI) to Facilitate Later Technology Transfer To and From Industry; and NOAA Satellite Programs and Technology Requirements. The panel discussion addresses the following major issues: DOD/NASA cooperation; alternative mechanisms for interagency communication and interactions; current technology transfer relationships among federal research agencies, and strategies for improving this transfer; technology transfer mechanisms appropriate to intragovernment transfer; the importance of industry as a technology transfer conduit; and measures of merit.

  11. 13 CFR 121.509 - What is the size standard for leasing of Government land for coal mining?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What is the size standard for leasing of Government land for coal mining? 121.509 Section 121.509 Business Credit and Assistance SMALL... leasing of Government land for coal mining? A concern is small for this purpose if it: (a) Together...

  12. Modeling Interactions in Small Groups

    ERIC Educational Resources Information Center

    Heise, David R.

    2013-01-01

    A new theory of interaction within small groups posits that group members initiate actions when tension mounts between the affective meanings of their situational identities and impressions produced by recent events. Actors choose partners and behaviors so as to reduce the tensions. A computer model based on this theory, incorporating reciprocal…

  13. Surveys explore critical governance relationship.

    PubMed

    Grant, M K

    1987-01-01

    The transition in religious-sponsored health care from a ministry of direct service to one of governance has generated serious and penetrating questions, analyses, and retrenchment. Emphasis on and demand for value-laden leadership development programs are growing at the same time that sponsoring groups are becoming more actively involved in the governance and oversight of their corporate ministries. Two recent Catholic Health Association (CHA) studies focused on the critical governance relationship between the sponsoring group and its incorporated ministries. The first study asked religious institutes and dioceses that were sponsors of CHA member health care freestanding facilities and systems to describe their current governance structure. The second study represented an initial attempt to identify qualitative components of effective governance or sponsorship and asked 19 major superiors and system chief executive officers (CEOs) to characterize an ideal relationship between sponsor and ministry. The studies' findings included the following: In freestanding facilities, lay-religious governing boards have all but replaced the all-sponsor and all-lay advisory boards of the past. Trustee orientation, development, and evaluation were not equally stressed in the three groups surveyed, with trustee evaluation programs lagging behind in all three. Major superiors and CEOs had remarkably similar expectations relating to accountability for mission, relationships between sponsor and corporation, communication, and leadership development. Both major superiors and CEOs looked for greater collaboration in defining roles, translating mission into "business plan", and developing formation programs for leadership. Major superiors' emphasized simplicity of life-style, whereas the CEOs stressed stable commitment to corporate ministry.

  14. Implementing a new governance model.

    PubMed

    Stanley-Clarke, Nicky; Sanders, Jackie; Munford, Robyn

    2016-05-16

    Purpose - The purpose of this paper is to discuss the lessons learnt from the process of implementing a new model of governance within Living Well, a New Zealand statutory mental health agency. Design/methodology/approach - It presents the findings from an organisational case study that involved qualitative interviews, meeting observations and document analysis. Archetype theory provided the analytical framework for the research enabling an analysis of both the formal structures and informal value systems that influenced the implementation of the governance model. Findings - The research found that the move to a new governance model did not proceed as planned. It highlighted the importance of staff commitment, the complexity of adopting a new philosophical approach and the undue influence of key personalities as key determining factors in the implementation process. The findings suggest that planners and managers within statutory mental health agencies need to consider the implications of any proposed governance change on existing roles and relationships, thinking strategically about how to secure professional commitment to change. Practical implications - There are ongoing pressures within statutory mental health agencies to improve the efficiency and effectiveness of organisational structures and systems. This paper has implications for how planners and managers think about the process of implementing new governance models within the statutory mental health environment in order to increase the likelihood of sustaining and embedding new approaches to service delivery. Originality/value - The paper presents insights into the process of implementing new governance models within a statutory mental health agency in New Zealand that has relevance for other jurisdictions. PMID:27119399

  15. Implementing a new governance model.

    PubMed

    Stanley-Clarke, Nicky; Sanders, Jackie; Munford, Robyn

    2016-05-16

    Purpose - The purpose of this paper is to discuss the lessons learnt from the process of implementing a new model of governance within Living Well, a New Zealand statutory mental health agency. Design/methodology/approach - It presents the findings from an organisational case study that involved qualitative interviews, meeting observations and document analysis. Archetype theory provided the analytical framework for the research enabling an analysis of both the formal structures and informal value systems that influenced the implementation of the governance model. Findings - The research found that the move to a new governance model did not proceed as planned. It highlighted the importance of staff commitment, the complexity of adopting a new philosophical approach and the undue influence of key personalities as key determining factors in the implementation process. The findings suggest that planners and managers within statutory mental health agencies need to consider the implications of any proposed governance change on existing roles and relationships, thinking strategically about how to secure professional commitment to change. Practical implications - There are ongoing pressures within statutory mental health agencies to improve the efficiency and effectiveness of organisational structures and systems. This paper has implications for how planners and managers think about the process of implementing new governance models within the statutory mental health environment in order to increase the likelihood of sustaining and embedding new approaches to service delivery. Originality/value - The paper presents insights into the process of implementing new governance models within a statutory mental health agency in New Zealand that has relevance for other jurisdictions.

  16. Influence of Environmental Governance on Deforestation in Municipalities of the Brazilian Amazon

    PubMed Central

    Dias, Lilian Fernandes Oliveira; Dias, David Valentim; Magnusson, William Ernest

    2015-01-01

    It has been argued that measuring governance at scales smaller than global could be an important management tool. However, current studies are conducted on a global scale and use expensive methods. In the present study, we assess whether the reported governance of Amazonian municipalities is related to reductions in deforestation. Economic activity (EA) affected general governance (G) positively (G = 0.81 +1.19 * EA, F1, 98 = 77.36, p < 0.001). Environmental governance (EG) was not affected significantly (p = 0.43) by deforestation before 2000 (PD), but increased significantly (p < 0.001) with general governance (G) (EG = -0.29 + 0.04 PD+0.98*OG, F2,97 = 42.6, p <0.001). Deforestation was not significantly related to environmental governance (p = 0.82). The only indirect effect of significant magnitude was the effect of the density of forest reserves on recent deforestation through deforestation before 2000, which was strongly negative (-0.49). It is possible to assess reported actions to promote municipal governance through official data. However, it is not enough to assume that general governance or environmental governance at the municipal level, as reflected in the official statistics, benefits environmental conservation. In fact, even at the level of nation states, at which most quantification of governance has been undertaken, it seems that the relationship between governance and environmental preservation is only an assumption, because we are aware of no study that supports that hypothesis quantitatively. PMID:26208282

  17. Influence of Environmental Governance on Deforestation in Municipalities of the Brazilian Amazon.

    PubMed

    Dias, Lilian Fernandes Oliveira; Dias, David Valentim; Magnusson, William Ernest

    2015-01-01

    It has been argued that measuring governance at scales smaller than global could be an important management tool. However, current studies are conducted on a global scale and use expensive methods. In the present study, we assess whether the reported governance of Amazonian municipalities is related to reductions in deforestation. Economic activity (EA) affected general governance (G) positively (G = 0.81 +1.19 * EA, F1, 98 = 77.36, p < 0.001). Environmental governance (EG) was not affected significantly (p = 0.43) by deforestation before 2000 (PD), but increased significantly (p < 0.001) with general governance (G) (EG = -0.29 + 0.04 PD+0.98*OG, F2,97 = 42.6, p <0.001). Deforestation was not significantly related to environmental governance (p = 0.82). The only indirect effect of significant magnitude was the effect of the density of forest reserves on recent deforestation through deforestation before 2000, which was strongly negative (-0.49). It is possible to assess reported actions to promote municipal governance through official data. However, it is not enough to assume that general governance or environmental governance at the municipal level, as reflected in the official statistics, benefits environmental conservation. In fact, even at the level of nation states, at which most quantification of governance has been undertaken, it seems that the relationship between governance and environmental preservation is only an assumption, because we are aware of no study that supports that hypothesis quantitatively.

  18. Influence of Environmental Governance on Deforestation in Municipalities of the Brazilian Amazon.

    PubMed

    Dias, Lilian Fernandes Oliveira; Dias, David Valentim; Magnusson, William Ernest

    2015-01-01

    It has been argued that measuring governance at scales smaller than global could be an important management tool. However, current studies are conducted on a global scale and use expensive methods. In the present study, we assess whether the reported governance of Amazonian municipalities is related to reductions in deforestation. Economic activity (EA) affected general governance (G) positively (G = 0.81 +1.19 * EA, F1, 98 = 77.36, p < 0.001). Environmental governance (EG) was not affected significantly (p = 0.43) by deforestation before 2000 (PD), but increased significantly (p < 0.001) with general governance (G) (EG = -0.29 + 0.04 PD+0.98*OG, F2,97 = 42.6, p <0.001). Deforestation was not significantly related to environmental governance (p = 0.82). The only indirect effect of significant magnitude was the effect of the density of forest reserves on recent deforestation through deforestation before 2000, which was strongly negative (-0.49). It is possible to assess reported actions to promote municipal governance through official data. However, it is not enough to assume that general governance or environmental governance at the municipal level, as reflected in the official statistics, benefits environmental conservation. In fact, even at the level of nation states, at which most quantification of governance has been undertaken, it seems that the relationship between governance and environmental preservation is only an assumption, because we are aware of no study that supports that hypothesis quantitatively. PMID:26208282

  19. Federal government expands compliance initiatives.

    PubMed

    Dugan, J K

    1997-09-01

    In 1995, the Federal government initiated Operation Restore Trust to increase enforcement of fraud and abuse regulations in Medicare and Medicaid programs. With the success of the original initiative, the government is expanding the project to additional states and program areas. The initial scrutiny of home health agencies, nursing homes, hospice care, and durable medical equipment is being expanded to managed care plans and acute care hospitals with an eye toward DRG creep. To manage this increased enforcement activity, healthcare organizations should institute comprehensive corporate compliance programs. Such programs should provide a framework that delineates responsibilities and provides a systematic means to resolve issues in a timely manner. PMID:10170318

  20. Federal government expands compliance initiatives.

    PubMed

    Dugan, J K

    1997-09-01

    In 1995, the Federal government initiated Operation Restore Trust to increase enforcement of fraud and abuse regulations in Medicare and Medicaid programs. With the success of the original initiative, the government is expanding the project to additional states and program areas. The initial scrutiny of home health agencies, nursing homes, hospice care, and durable medical equipment is being expanded to managed care plans and acute care hospitals with an eye toward DRG creep. To manage this increased enforcement activity, healthcare organizations should institute comprehensive corporate compliance programs. Such programs should provide a framework that delineates responsibilities and provides a systematic means to resolve issues in a timely manner.

  1. Geoengineering Policy and Governance Issues

    NASA Astrophysics Data System (ADS)

    Low, Sean; Moore, Nigel; Chen, Zhewen; McManamen, Keith; Blackstock, Jason J.

    Geoengineering - the deliberate and technological manipulation of the climate system to forestall the worst effects of global warming (also referred to as climate engineering) - has recently emerged as a novel and controversial issue in climate governance. It is sometimes proposed as an insurance policy, should either (a) primary efforts to develop sustainable energy and societal systems prove unable to quickly enough overcome the inertia of current ones, or (b) uncertainty in the climate system lead to unexpectedly large damage to societies and ecosystems [1]. This entry explores the current attempts and future ideas for governing emerging geoengineering research programs and technologies in ways that effectively manage their climatic and societal impacts.

  2. Assessment of government tribology programs

    SciTech Connect

    Peterson, M.B.; Levinson, T.M.

    1985-09-01

    An assessment has been made to determine current tribology research and development work sponsored or conducted by the government. Data base surveys and discussions were conducted to isolate current projects sponsored primarily by 21 different government organizations. These projects were classified by subject, objective, energy relevance, type of research, phenomenon being investigated, variables being studied, type of motion, materials and application. An abstract of each project was prepared which included the classification, sponsor, performing organization and a project description. It was found that current work is primarily materials oriented to meet military requirements. Other than the high temperature programs very few of the tribology projects accomplish energy related objectives.

  3. PROFESSIONAL REGISTRATION OF GOVERNMENT ENGINEERS.

    USGS Publications Warehouse

    Buchanan, Thomas J.

    1985-01-01

    The American Society of Civil Engineers views professional registration as an appropriate requirement for engineers, including those in government. The National Society of Professional Engineers makes registration a requirement for the grade of member and full privileges in the society. Some Federal agencies require engineering registration for certain positions in their agencies. Engineers in government service should consider the value of engineering registration to themselves and to their agencies and take pride in their professions and in their own capabilities by becoming registered engineers. They should also take steps to encourage their agencies to give more attention to engineering registration.

  4. Local governments LANDSAT applications program

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The approach used to develop the internal capabilities of local governments to handle and evaluate LANDSAT data included remote sensing training, development of a low-cost digital image processing system, and technical assistance. Cost sharing, program management and coordination, and networking were also employed to address problems related to land use, water resources, environmental assessment, and air quality as experienced by urban planners. Local experiences gained in Atlanta, Georgia; Henrico County, Virginia; Oklahoma City; Oklahoma; and San Jose, California are described. Policy recommendations formulated for transferring remote sensing technologies to local governments are included.

  5. Dawn Usage, Scheduling, and Governance Model

    SciTech Connect

    Louis, S

    2009-11-02

    This document describes Dawn use, scheduling, and governance concerns. Users started running full-machine science runs in early April 2009 during the initial open shakedown period. Scheduling Dawn while in the Open Computing Facility (OCF) was controlled and coordinated via phone calls, emails, and a small number of controlled banks. With Dawn moving to the Secure Computing Facility (SCF) in fall of 2009, a more detailed scheduling and governance model is required. The three major objectives are: (1) Ensure Dawn resources are allocated on a program priority-driven basis; (2) Utilize Dawn resources on the job mixes for which they were intended; and (3) Minimize idle cycles through use of partitions, banks and proper job mix. The SCF workload for Dawn will be inherently different than Purple or BG/L, and therefore needs a different approach. Dawn's primary function is to permit adequate access for tri-lab code development in preparation for Sequoia, and in particular for weapons multi-physics codes in support of UQ. A second purpose is to provide time allocations for large-scale science runs and for UQ suite calculations to advance SSP program priorities. This proposed governance model will be the basis for initial time allocation of Dawn computing resources for the science and UQ workloads that merit priority on this class of resource, either because they cannot be reasonably attempted on any other resources due to size of problem, or because of the unavailability of sizable allocations on other ASC capability or capacity platforms. This proposed model intends to make the most effective use of Dawn as possible, but without being overly constrained by more formal proposal processes such as those now used for Purple CCCs.

  6. IT Governance in SMEs: Trust or Control?

    NASA Astrophysics Data System (ADS)

    Devos, Jan; van Landeghem, Hendrik; Deschoolmeester, Dirk

    It is believed by many scholars that a small and medium-sized enterprise (SME) cannot be seen through the lens of a large firm. Theories which explain IT governance in large organizations and methodologies used by practitioners can therefore not be extrapolated to SMEs, which have a completely different economic, cultural and managerial environment. SMEs suffer from resource poverty, have less IS experience and need more external support. SMEs largely contribute to the failure of many IS projects. We define an outsourced information system failure (OISF) as a failure of IT governance in an SME environment and propose a structure for stating propositions derived from both agency theory and theory of trust. The theoretical question addressed in this paper is: how and why do OISFs occur in SMEs? We have chosen a qualitative and positivistic IS case study research strategy based on multiple cases. Eight cases of IS projects were selected. We found that trust is more important than control issues like output-based contracts and structured controls for eliminating opportunistic behaviour in SMEs. We conclude that the world of SMEs is significantly different from that of large companies. This necessitates extra care to be taken on the part of researchers and practitioners when designing artefacts for SMEs.

  7. Business, households, and governments: Health care costs, 1990

    PubMed Central

    Levit, Katharine R.; Cowan, Cathy A.

    1991-01-01

    This annual article presents information on health care costs by business, households, and government. Households funded 35 percent of expenditures in 1990, government 33 percent, and business, 29 percent. During the last decade, health care costs continued to grow at annual rates of 8 to 16 percent. Burden measures show that rapidly rising costs faced by each sponsor sector are exceeding increases in each sector's ability to fund them. Increased burden is particularly acute for business. The authors discuss the problems these rising costs pose for business, particularly small business, and some of the strategies businesses employ to constrain this cost growth. PMID:10122364

  8. Mental health network governance: comparative analysis across Canadian regions

    PubMed Central

    Wiktorowicz, Mary E; Fleury, Marie-Josée; Adair, Carol E; Lesage, Alain; Goldner, Elliot; Peters, Suzanne

    2010-01-01

    Objective Modes of governance were compared in ten local mental health networks in diverse contexts (rural/urban and regionalized/non-regionalized) to clarify the governance processes that foster inter-organizational collaboration and the conditions that support them. Methods Case studies of ten local mental health networks were developed using qualitative methods of document review, semi-structured interviews and focus groups that incorporated provincial policy, network and organizational levels of analysis. Results Mental health networks adopted either a corporate structure, mutual adjustment or an alliance governance model. A corporate structure supported by regionalization offered the most direct means for local governance to attain inter-organizational collaboration. The likelihood that networks with an alliance model developed coordination processes depended on the presence of the following conditions: a moderate number of organizations, goal consensus and trust among the organizations, and network-level competencies. In the small and mid-sized urban networks where these conditions were met their alliance realized the inter-organizational collaboration sought. In the large urban and rural networks where these conditions were not met, externally brokered forms of network governance were required to support alliance based models. Discussion In metropolitan and rural networks with such shared forms of network governance as an alliance or voluntary mutual adjustment, external mediation by a regional or provincial authority was an important lever to foster inter-organizational collaboration. PMID:21289999

  9. [HIV/AIDS in South Africa and Haiti: the failure of epidemic governance and achievement of the MDGs].

    PubMed

    Thelot, Fils-Lien Ely

    2009-01-01

    Since their adoption in 2000 by the United Nations, the Millennium Development Goals set for 2015 appear to have become a part of the policy agenda of all of the member states. Three of these eight objectives deal with health issues. "Combat HIV/AIDS, malaria and other diseases": this is the formulation of the sixth MDG. Observing that in many countries strongly affected by poverty and inequalities, the epidemic continues to spread, without really reversing at all, and that access to antiretrovirals is possible for only a small proportion of the patient who need them, we consider the problems of global governance in the field of health. Our intention is to explain that the failure to deal with the HIV/AIDS epidemic may constitute an obstacle to the achievement of the MDGs by 2015. Proposing a comprehensive sociology of HIV/AIDS, this article pays special attention to the dimension of the meaning of the disease, simultaneously as a policy issue, a social construction, and an object of study in the social sciences. Looking at the two countries most affected by the epidemic in Africa and in the Caribbean, we examine the different aspects that have determined the failure of governance and the effects of this failure on the populations concerned. The excessive conflictuality in South Africa and the biopolitics of "let them die" and the fragmentation of the networks involved in the combat in Haiti are considered to have contributed to a crisis in the epidemic's governance. In both cases, the consequences have been expressed by a reduced life expectancy, insufficient access to antiretroviral drugs, reinforcement of the socioeconomic inequalities of health, the production of new pockets of poverty, more fragile household and national economies, an increase in maternal and child mortality ... The failure of the governance of the HIV/AIDS epidemic in countries such as Haiti and South Africa appears to foretell the impossibility of achieving the MDGs by 2015. PMID:20185388

  10. (Duplicate Work Item) Finances of County Governments: 2002. Census of Governments. Vol. 4, No. 3, Government Finances.

    ERIC Educational Resources Information Center

    US Department of Commerce, 2005

    2005-01-01

    "Government Finances, Volume 4", contains six parts that encompass the entire range of state and local government financial activity in fiscal year 2001-02. They are: (1)Finances of Public School Systems; (2) Finances of Special Districts; (3) Finances of County Governments; (4) Finances of Municipal and Township Governments; (5) Compendium of…

  11. Local government cooperating to protect groundwater

    SciTech Connect

    Lundberg, M.D. )

    1990-01-01

    In the early 1980's, Minnesota policymakers worked to establish a cooperative local-state effort in southeastern Minnesota to protect groundwater. Two task forces were formed for the purpose of considering new or stronger regulations concerning sinkholes, water wells, individual sewage systems, feedlots, erosion control and solid waste. The Comprehensive Local Water Planning Act was passed in 1985. Plan preparation is voluntary and the process is flexible. Each county develops its own plan but it must coordinate with other affected local entities. The plan must address groundwater and surface water and related issues, soil erosion, and special geologic conditions. It requires public participation in plan development. The newly developed Minnesota Ground Water Protection Act of 1989 strengthens Minnesota's groundwater policy framework; protects drinking water supplies; provides for education, research, monitoring, and information management; improves control of pollution sources; and provides a key role for local government. Local government has proven to be a valuable partner in the task of protecting groundwater resources. It is close to the people, has broad land use and health authorities and uses of the water.

  12. Science in the Federal Government.

    ERIC Educational Resources Information Center

    Thibodeau, Sharon Gibbs

    1985-01-01

    Examines the realm of science and the federal government made evident in the 1950s by A. Hunter Dupree's classic work on the subject. Federal science before 1940, federal science since 1940, and sources of historical materials are among the major areas considered. (JN)

  13. Collection Development Policy: Government Information.

    ERIC Educational Resources Information Center

    Blazek, Dan

    Intended as a general guideline for selecting government documents at the University of Miami (Florida) Otto G. Richter Library, this collection development policy includes the following sections: (1) Introduction; (2) Mission Statement; (3) Selection Responsibility; (4) Subject Areas, Collection Intensity Levels and Collection Arrangement,…

  14. Gender Play and Good Governance

    ERIC Educational Resources Information Center

    Powell, Mark

    2008-01-01

    Like good government, thoughtful care of children requires those in power, whether teachers or parents, to recognize when it is appropriate for them to step back from day-to-day decision-making while still working behind the scenes to ensure an organizational structure that supports the independence and equitable development of those they serve.…

  15. Global Trends in Academic Governance

    ERIC Educational Resources Information Center

    Cummings, William K.; Finkelstein, Martin

    2009-01-01

    Even before the current global economic crisis, discontent with the governance of higher education institutions was widespread among faculty in the United States and throughout the world. Drawing from the 2007 Changing Academic Profession (CAP) survey of faculty in seventeen countries, the authors examine faculty perceptions of the current state…

  16. Do Kids Need Government Censors?

    ERIC Educational Resources Information Center

    Rabkin, Rhoda

    2002-01-01

    Fashioning public policies restricting children's access to entertainment glamorizing violence, sex, drugs, and vulgarity is a complex task. The recently introduced Media Marketing Accountability Act would empower the federal government to regulate advertising of entertainment products to youth. Suggests that this power is undesirable compared to…

  17. Campus Life and Government Investigations.

    ERIC Educational Resources Information Center

    Shekleton, James F.

    This paper discusses the proper way to conduct official government investigations on college campuses within the framework of the Fourth Amendment to the United States Constitution which protects against unreasonable searches and seizures. The article emphasizes that this amendment lays the groundwork for the limitations on the exercise of…

  18. Refocusing Government-Communications Policy.

    ERIC Educational Resources Information Center

    Pool, Ithiel de Sola; And Others

    In 1976, the Aspen Institute's Program on Communications and Society sponsored a series of Washington staff seminars on communications policy: "Policy Choices for the Information Age,""Government Telecommunications Research and Policy Development,""Problems of Regulating Specialized Telecommunications Common Carriers," and "Public Service Uses of…

  19. In Search of Good Governance

    ERIC Educational Resources Information Center

    Grush, Mary

    2007-01-01

    Since his retirement in 2005, UC-Berkeley's Associate Vice Chancellor and CIO Emeritus and current ECAR fellow John (Jack) McCredie has devoted much of his professional energy to studying and writing/speaking about IT governance and leadership in higher education. In his role at UC-Berkeley, he was responsible for leading central IT support for…

  20. Archeology and the Federal Government.

    ERIC Educational Resources Information Center

    Smith, George S., Comp.; And Others

    1988-01-01

    The U.S. Government's concern for preservation of important archeological properties began during the 19th century in response to the destruction and looting of Indian ruins in the U.S. Southwest. Since that time, the breadth of this concern has grown to include the consideration of impact to archeological properties, as well as to other kinds of…

  1. Seattle Schools' Governance under Fire

    ERIC Educational Resources Information Center

    Archer, Jeff

    2007-01-01

    This article reports on how Seattle has joined the growing list of urban districts where policymakers are eyeing changes in school governance. A bill pending in the Washington state legislature, introduced late January 2007 by three lawmakers from the city, would permit citizens to petition to hold a local referendum on switching from the elected…

  2. 76 FR 2001 - Government Property

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... rule at 73 FR 73202, December 2, 2008. The 60 day comment period for the proposed rule ended February 2... From the Federal Register Online via the Government Publishing Office ] NATIONAL AERONAUTICS AND... Aeronautics and Space Administration. ACTION: Final rule. SUMMARY: NASA is issuing a final rule to revise...

  3. Vietnam and American Government Textbooks.

    ERIC Educational Resources Information Center

    Cline, Paul C.; Eksterowicz, Anthony J.

    1998-01-01

    Discusses the importance of studying the Vietnam War. Attempts to illustrate the amount and quality of coverage of the Vietnam War in U.S. government textbooks. Explains that the amount of space devoted to the war in most of these texts remains inadequate for student understanding of the Vietnam War. (CMK)

  4. Teacher Unionization in School Governance

    ERIC Educational Resources Information Center

    Jacoby, Dan

    2011-01-01

    The role of unions in school governance is reviewed to note that labor operates in a larger context of principal-agent relationships. As agents for teachers, unions articulate the concerns that must be addressed if teachers are to be successfully enlisted in the struggle to reduce achievement gaps among at-risk students. Transcending industrial…

  5. Financial Responsibilities of Governing Boards.

    ERIC Educational Resources Information Center

    Reed, William S.

    2001-01-01

    This completely redone edition is meant to be a primer on the financial responsibilities of trustees of colleges and universities and on complex trends and issues bearing on the responsibilities of governing boards. Trustees must deal with a complex blend of competing values, evolving information, and challenging analyses while taking into account…

  6. Neutrality between Government and Religion.

    ERIC Educational Resources Information Center

    Mawdsley, Ralph D.

    1996-01-01

    The overall guiding principle of neutrality between government and religion masks a tension that exists between free exercise of religion and establishment of religion. Reviews the development and current status of "Lemon" as a test for neutrality; proposes a new test for neutrality, evenhandedness, that is common to both the Free Exercise and…

  7. Government Documents Go to School

    ERIC Educational Resources Information Center

    Williams, Sandra Q.

    2005-01-01

    In the fall of 2002, the author conducted brief surveys of the teacher and teacher-librarians in her graduate cataloging class and in a colleage's media selection class to learn whether and how government documents are used in the schools where these students were employed. The schools included in the surveys were in several central Minnesota…

  8. Campus Life and Government Investigations.

    ERIC Educational Resources Information Center

    Leed, Arthur

    As more government agencies request information and records from colleges and universities, it is important that all institutions establish standard procedures for handling such requests. Administrators should: learn the personality of the particular agency or office making the request; establish a professional, cooperative, non-adversarial…

  9. Reproductive governance in Latin America.

    PubMed

    Morgan, Lynn M; Roberts, Elizabeth F S

    2012-01-01

    This paper develops the concept of reproductive governance as an analytic tool for tracing the shifting political rationalities of population and reproduction. As advanced here, the concept of reproductive governance refers to the mechanisms through which different historical configurations of actors - such as state, religious, and international financial institutions, NGOs, and social movements - use legislative controls, economic inducements, moral injunctions, direct coercion, and ethical incitements to produce, monitor, and control reproductive behaviours and population practices. Examples are drawn from Latin America, where reproductive governance is undergoing a dramatic transformation as public policy conversations are coalescing around new moral regimes and rights-based actors through debates about abortion, emergency contraception, sterilisation, migration, and assisted reproductive technologies. Reproductive discourses are increasingly framed through morality and contestations over 'rights', where rights-bearing citizens are pitted against each other in claiming reproductive, sexual, indigenous, and natural rights, as well as the 'right to life' of the unborn. The concept of reproductive governance can be applied to other settings in order to understand shifting political rationalities within the domain of reproduction. PMID:22889430

  10. Governance of Children's Everyday Spaces

    ERIC Educational Resources Information Center

    Cobb, Charlotte; Danby, Susan; Farrell, Ann

    2005-01-01

    With the emergence of sociological and economic change there is increasing attention given to governance of children's spaces in recent years. This paper discusses these changes and how they have impacted on, and contributed to, this increased interest. The paper draws on the sociology of childhood framework in order to examine how children…

  11. Is shared governance still relevant?

    PubMed

    Porter-O'Grady, T

    2001-10-01

    Is shared governance still relevant in this era of significant changes in healthcare? Requisites to support nurses and others are more important now than ever before. Shared decision-making is not only relevant, it is essential. The road to empowerment is not easy. Many patterns of organization and relationship must be changed forever through commitment and leadership today.

  12. Native Americans and state and local governments

    SciTech Connect

    Rusco, E.R.

    1991-10-01

    Native Americans` concerns arising from the possibility of establishment of a nuclear repository for high level wastes at Yucca Mountain fall principally into two main categories. First, the strongest objection to the repository comes from traditional Western Shoshones. Their objections are based on a claim that the Western Shoshones still own Yucca Mountain and also on the assertion that putting high level nuclear wastes into the ground is a violation of their religious views regarding nature. Second, there are several reservations around the Yucca Mountain site that might be affected in various ways by building of the repository. There is a question about how many such reservations there are, which can only be decided when more information is available. This report discusses two questions: the bearing of the continued vigorous assertion by traditionalist Western Shoshones of their land claim; and the extent to which Nevada state and local governments are able to understand and represent Indian viewpoints about Yucca Mountain.

  13. 75 FR 33657 - Notification of a Public Meeting and Mailbox on the Presidential Memorandum on Federal Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION DEPARTMENT OF COMMERCE OFFICE OF MANAGEMENT AND BUDGET Notification of a Public Meeting and Mailbox on the Presidential Memorandum on Federal Small Business Contracting AGENCY: Small...

  14. 78 FR 4968 - Privacy Act of 1974, Computer Matching Program-U.S. Small Business Administration and U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    .... Department of Homeland Security, Federal Emergency Management Agency AGENCY: U.S. Small Business.... Department of Homeland Security, Federal Emergency Management Agency. SUMMARY: The U.S. Small Business... From the Federal Register Online via the Government Publishing Office SMALL...

  15. Governing boards and profound organizational change in hospitals.

    PubMed

    Fennell, M L; Alexander, J A

    1989-01-01

    Over the past decade the importance of governing boards as policy-making setting and oversight units within organizations has increased dramatically. Although this is true for both corporate- and private-sector organizations (Bacon and Brown 1977; Gelman 1988), it is particularly relevant to the health sector. Hospital governing boards, long considered inconsequential in hospital management, have recently become subject to closer scrutiny. The role of governing boards in decisions affecting hospital strategy and hospital performance is once again a topic of some interest in boardrooms and hospital trade journals. Impressive evidence of the renewed interest in governance is provided by the funding of an instructional consortium by the S.K. Kellogg Foundation to help strengthen trusteeship and governing board decision making, and to improve education for health services managers in the area of governance. Members of the consortium include the Hospital Research and Educational Trust, the American Hospital Association, the American College of Healthcare Executives, and the Association for University Programs in Health Administration. Among the activities being undertaken by this consortium is the development of a self-assessment tool/methodology for boards, a bibliography and reference guide on effective governance for practicing trustees, research workshops for faculty in health administration programs, and a teaching guide on governance and trustee leadership. Despite this interest, the question with which we began this article persists. Do governing boards make a difference? In the course of our review of previous work on governance we found that, more often than not, that question has been transformed into: how do boards influence hospital performance? And very often that question has been further narrowed into: which board structure leads to better hospital performance? We have argued for a respecification of the initial question. Rather than pursuing a definition

  16. Implicit Contracts Regulating Small Group Leadership: The Influence of Culture.

    ERIC Educational Resources Information Center

    Zamarripa, Perrin Orr; Krueger, Dorothy Lenk

    1983-01-01

    Examined culture variables in the negotiation of implicit rules which govern leadership behavior in small groups. American, French, and Arab students (N=42) were assigned identical decision-making tasks. Results showed monocultural groups presented homogeneous rules governing leadership prior to interaction, while intercultural groups presented…

  17. 76 FR 11307 - Small Business Information Security Task Force

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS... scope requirements for the Task Force with specific questions of Identity Theft, Privacy, and Government Contracting information. Additionally, resource and staffing issues to support the work of the Task Force...

  18. 78 FR 59798 - Small Business Subcontracting: Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... final regulations [FR Doc. 2013-169671, which were published in the Federal Register on Tuesday, July 16, 2013 (78 FR 42391). The document amended SBA's regulations governing small business subcontracting to...: Background On July 16, 2013, at 78 FR 42392 (available at...

  19. Informatics and Small Computers in Latin America.

    ERIC Educational Resources Information Center

    Alvarez, Jose; And Others

    1985-01-01

    This paper highlights potential benefits and more pressing social and legal problems facing Latin American nations in the area of informatics and small computers. Discussion covers potential uses (education, office applications, agriculture, national planning); role of central governments; implications for economic development; and transborder…

  20. Small Schools and the Pressure to Consolidate

    ERIC Educational Resources Information Center

    Howley, Aimee; Howley, Craig

    2006-01-01

    Positioned in relationship to reform literature calling for small schools "by design" and interpreting data from a case study of a high performing but low-SES district in a Midwestern state, this paper provides a basis for making sense of the apparent divergence in policies governing schooling structures in rural and urban places. Its…

  1. Computing Strategies in Small Universities and Colleges.

    ERIC Educational Resources Information Center

    Coughlin, Patrick J.

    A survey was conducted to identify the patterns of academic and administrative computer services in use--or planned for the near future--in small colleges and universities as they relate to such strategic policy areas as: (1) management/governance structure; (2) personnel-staff; (3) personnel-faculty; (4) academic computing; (5) library services;…

  2. Legislation: Legislation and Regulations Affecting Libraries in 2002; Legislation and Regulations Affecting Publishing in 2002.

    ERIC Educational Resources Information Center

    Sheketoff, Emily; Costabile, Mary R.; Adler, Allan

    2003-01-01

    Reviews legislation and regulations affecting libraries and the publishing industry, including the Museum and Library Services Act; Office of Educational Research and Improvement (OERI); copyright; access to electronic government information; telecommunications and technology; electronic surveillance and privacy, including the USA Patriot Act;…

  3. Social Justice, Policy and Parents' Understanding of Their Voice in School Governing Bodies in South Africa

    ERIC Educational Resources Information Center

    Mncube, Vusi S.

    2007-01-01

    Despite the powers that parents are endowed with regarding governance of schools in South Africa, they are not yet given sufficient room and space to deliberate on issues of school governance; instead they are still excluded by some teaching staff who deny them (explicitly or implicitly) from taking part in crucial decisions affecting education of…

  4. 46 CFR 280.3 - Standards governing award of an ODS agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standards governing award of an ODS agreement. 280.3 Section 280.3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING... LINER OPERATORS § 280.3 Standards governing award of an ODS agreement. No ODS agreement, including...

  5. 31 CFR 0.203 - Gifts or gratuities from foreign governments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... foreign governments. (a) The United States Constitution prohibits employees from accepting gifts... cause offense or embarrassment or otherwise adversely affect the foreign relations of the United States... governments. 0.203 Section 0.203 Money and Finance: Treasury Office of the Secretary of the...

  6. 22 CFR 221.43 - Governing law.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the...

  7. 42 CFR 460.62 - Governing body.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Governing body. 460.62 Section 460.62 Public Health... Administrative Requirements § 460.62 Governing body. (a) Governing body. A PACE organization must be operating under the control of an identifiable governing body (for example, a board of directors) or a...

  8. 22 CFR 221.43 - Governing law.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the...

  9. 22 CFR 221.43 - Governing law.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the...

  10. 22 CFR 221.43 - Governing law.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the...

  11. 22 CFR 232.16 - Governing law.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Governing law. 232.16 Section 232.16 Foreign...-74-STANDARD TERMS AND CONDITIONS § 232.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and...

  12. 22 CFR 232.16 - Governing law.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Governing law. 232.16 Section 232.16 Foreign...-74-STANDARD TERMS AND CONDITIONS § 232.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and...

  13. Computerized and Networked Government Information Column

    ERIC Educational Resources Information Center

    Stratford, Juri

    2004-01-01

    The efforts of the U.S. federal government to develop E-Government services have been the subject of many recent news stories. In February 2002, Arthur Andersen's Office of Government Services released a usability analysis of federal government Web sites. In addition, in February, Vice-President Cheney announced the release of a report detailing…

  14. Governance and Trust in Higher Education

    ERIC Educational Resources Information Center

    Vidovich, Lesley; Currie, Jan

    2011-01-01

    The adoption of more corporate models of governance is a contemporary trend in higher education. In the early 2000s, the Australian Government legislated national governance protocols for universities, using the policy lever of financial sanctions. These more corporate-style governance protocols followed similar changes in the UK, consistent with…

  15. 42 CFR 51c.304 - Governing board.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Governing board. 51c.304 Section 51c.304 Public... SERVICES Grants for Operating Community Health Centers § 51c.304 Governing board. A governing board for the... members. The method of selection of all governing board members shall be prescribed in the by-laws...

  16. 42 CFR 51c.304 - Governing board.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Governing board. 51c.304 Section 51c.304 Public... SERVICES Grants for Operating Community Health Centers § 51c.304 Governing board. A governing board for the... members. The method of selection of all governing board members shall be prescribed in the by-laws...

  17. 22 CFR 221.43 - Governing law.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the...

  18. 22 CFR 204.43 - Governing law.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Governing law. 204.43 Section 204.43 Foreign... § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the United...

  19. 42 CFR 51c.304 - Governing board.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Governing board. 51c.304 Section 51c.304 Public... SERVICES Grants for Operating Community Health Centers § 51c.304 Governing board. A governing board for the... members. The method of selection of all governing board members shall be prescribed in the by-laws...

  20. 22 CFR 231.16 - Governing law.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Governing law. 231.16 Section 231.16 Foreign... § 231.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the United...

  1. 7 CFR 25.501 - Governments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Governments. 25.501 Section 25.501 Agriculture Office....501 Governments. If more than one State or local government seeks to nominate an area under this part, any reference to or requirement of this part shall apply to all such governments....

  2. 7 CFR 25.501 - Governments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Governments. 25.501 Section 25.501 Agriculture Office....501 Governments. If more than one State or local government seeks to nominate an area under this part, any reference to or requirement of this part shall apply to all such governments....

  3. 24 CFR 598.505 - Governments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Governments. 598.505 Section 598.505... Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part applies to all such governments....

  4. 24 CFR 598.505 - Governments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Governments. 598.505 Section 598.505... Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part applies to all such governments....

  5. 24 CFR 598.505 - Governments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Governments. 598.505 Section 598....505 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part applies to all such governments....

  6. 2 CFR 25.340 - Local government.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Local government. 25.340 Section 25.340... CENTRAL CONTRACTOR REGISTRATION Definitions § 25.340 Local government. Local government means a: (a... district; (j) School district; (k) Intrastate district; (l) Council of governments, whether or...

  7. 22 CFR 62.29 - Government visitors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Government visitors. 62.29 Section 62.29... Program Provisions § 62.29 Government visitors. (a) Purpose. The government visitor category is for the exclusive use of the U.S. federal, state, or local government agencies. Programs under this section are...

  8. 25 CFR 700.531 - Government property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and...

  9. 24 CFR 597.501 - Governments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Governments. 597.501 Section 597... Special Rules § 597.501 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part shall apply to all such governments....

  10. 24 CFR 597.501 - Governments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Governments. 597.501 Section 597... Special Rules § 597.501 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part shall apply to all such governments....

  11. 25 CFR 700.531 - Government property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and...

  12. 22 CFR 62.29 - Government visitors.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Government visitors. 62.29 Section 62.29... Program Provisions § 62.29 Government visitors. (a) Purpose. The government visitor category is for the exclusive use of the U.S. federal, state, or local government agencies. Programs under this section are...

  13. 24 CFR 598.505 - Governments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Governments. 598.505 Section 598....505 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part applies to all such governments....

  14. 24 CFR 597.501 - Governments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Governments. 597.501 Section 597.501... Rules § 597.501 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part shall apply to all such governments....

  15. 7 CFR 25.501 - Governments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Governments. 25.501 Section 25.501 Agriculture Office....501 Governments. If more than one State or local government seeks to nominate an area under this part, any reference to or requirement of this part shall apply to all such governments....

  16. 7 CFR 25.501 - Governments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Governments. 25.501 Section 25.501 Agriculture Office....501 Governments. If more than one State or local government seeks to nominate an area under this part, any reference to or requirement of this part shall apply to all such governments....

  17. 24 CFR 598.505 - Governments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Governments. 598.505 Section 598....505 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part applies to all such governments....

  18. 25 CFR 700.531 - Government property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and...

  19. 24 CFR 597.501 - Governments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Governments. 597.501 Section 597... Special Rules § 597.501 Governments. If more than one State or local government seeks to nominate an urban area under this part, any reference to or requirement of this part shall apply to all such governments....

  20. 22 CFR 62.29 - Government visitors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Government visitors. 62.29 Section 62.29... Program Provisions § 62.29 Government visitors. (a) Purpose. The government visitor category is for the exclusive use of the U.S. federal, state, or local government agencies. Programs under this section are...