Grain orientation effects on dynamic strength of FCC multicrystals at low shock pressures: a hydrodynamic instability study

DOE PAGES

Peralta, P.; Loomis, E.; Chen, Y.; ...

2015-04-09

Variability in local dynamic plasticity due to material anisotropy in polycrystalline metals is likely to be important on damage nucleation and growth at low pressures. Hydrodynamic instabilities could be used to study these plasticity effects by correlating measured changes in perturbation amplitudes at free surfaces to local plastic behaviour and grain orientation, but amplitude changes are typically too small to be measured reliably at low pressures using conventional diagnostics. Correlations between strength at low shock pressures and grain orientation were studied in copper (grain size ≈ 800 μm) using the Richtmyer–Meshkov instability with a square-wave surface perturbation (wavelength = 150 μm, amplitude = 5 μm), shocked at 2.7 GPa using symmetric plate impacts. A Plexiglas window was pressed against the peaks of the perturbation, keeping valleys as free surfaces. This produced perturbation amplitude changes much larger than those predicted without the window. Amplitude reductions from 64 to 88% were measured in recovered samples and grains oriented close tomore » $$\\langle$$0 0 1$$\\rangle$$ parallel to the shock had the largest final amplitude, whereas grains with shocks directions close to $$\\langle$$1 0 1$$\\rangle$$ had the lowest. Finite element simulations were performed with elastic-perfectly plastic models to estimate yield strengths leading lead to those final amplitudes. Anisotropic elasticity and these yield strengths were used to calculate the resolved shear stresses at yielding for the two orientations. In conclusion, results are compared with reports on orientation dependence of dynamic yielding in Cu single crystals and the higher values obtained suggest that strength estimations via hydrodynamic instabilities are sensitive to strain hardening and strain rate effects.« less

Analysis of Plastic Flow Instability During Superplastic Deformation of the Zn-Al Eutectoid Alloy Modified with 2 wt.% Cu

NASA Astrophysics Data System (ADS)

Ramos-Azpeitia, Mitsuo; Elizabeth Martínez-Flores, E.; Hernandez-Rivera, Jose Luis; Torres-Villaseñor, Gabriel

2017-11-01

The aim of this work is to analyze the plastic flow instability in Zn-21Al-2Cu alloy deformed under 10-3 s-1 and 513 K, which are optimum conditions for inducing superplastic behavior in this alloy. An evaluation using the Hart and Wilkinson-Caceres criteria showed that the limited stability of plastic flow observed in this alloy is related to low values of the strain-rate sensitivity index ( m) and the strain-hardening coefficient ( γ), combined with the tendency of these parameters to decrease depending on true strain ( ɛ). The reduction in m and γ values could be associated with the early onset of plastic instability and with microstructural changes observed as function of the strain. Grain growth induced by deformation seems to be important during the first stage of deformation of this alloy. However, when ɛ > 0.4 this growth is accompanied by other microstructural rearrangements. These results suggest that in this alloy, a grain boundary sliding mechanism acts to allow a steady superplastic flow only for ɛ < 0.4. For ɛ values between 0.4 and 0.7, observed occurrences of microstructural changes and severe neck formation lead to the supposition that there is a transition in the deformation mechanism. These changes are more evident when ɛ > 0.7 as another mechanism is thought to take over.

Ratcheting fatigue behavior of Zircaloy-2 at room temperature

NASA Astrophysics Data System (ADS)

Rajpurohit, R. S.; Sudhakar Rao, G.; Chattopadhyay, K.; Santhi Srinivas, N. C.; Singh, Vakil

2016-08-01

Nuclear core components of zirconium alloys experience asymmetric stress or strain cycling during service which leads to plastic strain accumulation and drastic reduction in fatigue life as well as dimensional instability of the component. Variables like loading rate, mean stress, and stress amplitude affect the influence of asymmetric loading. In the present investigation asymmetric stress controlled fatigue tests were conducted with mean stress from 80 to 150 MPa, stress amplitude from 270 to 340 MPa and stress rate from 30 to 750 MPa/s to study the process of plastic strain accumulation and its effect on fatigue life of Zircaloy-2 at room temperature. It was observed that with increase in mean stress and stress amplitude accumulation of ratcheting strain was increased and fatigue life was reduced. However, increase in stress rate led to improvement in fatigue life due to less accumulation of ratcheting strain.

Experimental demonstration of laser imprint reduction using underdense foams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Delorme, B.; Casner, A.; CELIA, University of Bordeaux-CNRS-CEA, F-33400 Talence

2016-04-15

Reducing the detrimental effect of the Rayleigh-Taylor (RT) instability on the target performance is a critical challenge. In this purpose, the use of targets coated with low density foams is a promising approach to reduce the laser imprint. This article presents results of ablative RT instability growth measurements, performed on the OMEGA laser facility in direct-drive for plastic foils coated with underdense foams. The laser beam smoothing is explained by the parametric instabilities developing in the foam and reducing the laser imprint on the plastic (CH) foil. The initial perturbation pre-imposed by the means of a specific phase plate wasmore » shown to be smoothed using different foam characteristics. Numerical simulations of the laser beam smoothing in the foam and of the RT growth are performed with a suite of paraxial electromagnetic and radiation hydrodynamic codes. They confirmed the foam smoothing effect in the experimental conditions.« less

Slip-activated surface creep with room-temperature super-elongation in metallic nanocrystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, Li; Sansoz, Frederic; He, Yang

2016-11-28

Atom diffusion assisted by surfaces or interfaces (e.g. Coble creep) has been known to be the origin of large creep rates and superplastic softening in nanosized crystals at low temperature. By contrast, source-limited crystal slip in defect-free nanostructures engenders important strengths, but also premature plastic instability and low ductility. Here, using in-situ transmission electron microscopy, we report a slip-activated surface creep mechanism that suppresses the tendency towards plastic instability without compromising the strength, resulting in ultra-large room-temperature plasticity in face-centered-cubic silver nanocrystals. This phenomenon is shown experimentally and theoretically to prevail over a material-dependent range of diameters where surface dislocationmore » nucleation becomes a stimulus to diffusional creep. This work provides new fundamental insight into coupled diffusive-displacive deformation mechanisms maximizing ductility and strength simultaneously in nanoscale materials.« less

Mixing with applications to inertial-confinement-fusion implosions

NASA Astrophysics Data System (ADS)

Rana, V.; Lim, H.; Melvin, J.; Glimm, J.; Cheng, B.; Sharp, D. H.

2017-01-01

Approximate one-dimensional (1D) as well as 2D and 3D simulations are playing an important supporting role in the design and analysis of future experiments at National Ignition Facility. This paper is mainly concerned with 1D simulations, used extensively in design and optimization. We couple a 1D buoyancy-drag mix model for the mixing zone edges with a 1D inertial confinement fusion simulation code. This analysis predicts that National Ignition Campaign (NIC) designs are located close to a performance cliff, so modeling errors, design features (fill tube and tent) and additional, unmodeled instabilities could lead to significant levels of mix. The performance cliff we identify is associated with multimode plastic ablator (CH) mix into the hot-spot deuterium and tritium (DT). The buoyancy-drag mix model is mode number independent and selects implicitly a range of maximum growth modes. Our main conclusion is that single effect instabilities are predicted not to lead to hot-spot mix, while combined mode mixing effects are predicted to affect hot-spot thermodynamics and possibly hot-spot mix. Combined with the stagnation Rayleigh-Taylor instability, we find the potential for mix effects in combination with the ice-to-gas DT boundary, numerical effects of Eulerian species CH concentration diffusion, and ablation-driven instabilities. With the help of a convenient package of plasma transport parameters developed here, we give an approximate determination of these quantities in the regime relevant to the NIC experiments, while ruling out a variety of mix possibilities. Plasma transport parameters affect the 1D buoyancy-drag mix model primarily through its phenomenological drag coefficient as well as the 1D hydro model to which the buoyancy-drag equation is coupled.

Mixing with applications to inertial-confinement-fusion implosions.

PubMed

Rana, V; Lim, H; Melvin, J; Glimm, J; Cheng, B; Sharp, D H

2017-01-01

Approximate one-dimensional (1D) as well as 2D and 3D simulations are playing an important supporting role in the design and analysis of future experiments at National Ignition Facility. This paper is mainly concerned with 1D simulations, used extensively in design and optimization. We couple a 1D buoyancy-drag mix model for the mixing zone edges with a 1D inertial confinement fusion simulation code. This analysis predicts that National Ignition Campaign (NIC) designs are located close to a performance cliff, so modeling errors, design features (fill tube and tent) and additional, unmodeled instabilities could lead to significant levels of mix. The performance cliff we identify is associated with multimode plastic ablator (CH) mix into the hot-spot deuterium and tritium (DT). The buoyancy-drag mix model is mode number independent and selects implicitly a range of maximum growth modes. Our main conclusion is that single effect instabilities are predicted not to lead to hot-spot mix, while combined mode mixing effects are predicted to affect hot-spot thermodynamics and possibly hot-spot mix. Combined with the stagnation Rayleigh-Taylor instability, we find the potential for mix effects in combination with the ice-to-gas DT boundary, numerical effects of Eulerian species CH concentration diffusion, and ablation-driven instabilities. With the help of a convenient package of plasma transport parameters developed here, we give an approximate determination of these quantities in the regime relevant to the NIC experiments, while ruling out a variety of mix possibilities. Plasma transport parameters affect the 1D buoyancy-drag mix model primarily through its phenomenological drag coefficient as well as the 1D hydro model to which the buoyancy-drag equation is coupled.

Hot-spot mix in ignition-scale inertial confinement fusion targets.

PubMed

Regan, S P; Epstein, R; Hammel, B A; Suter, L J; Scott, H A; Barrios, M A; Bradley, D K; Callahan, D A; Cerjan, C; Collins, G W; Dixit, S N; Döppner, T; Edwards, M J; Farley, D R; Fournier, K B; Glenn, S; Glenzer, S H; Golovkin, I E; Haan, S W; Hamza, A; Hicks, D G; Izumi, N; Jones, O S; Kilkenny, J D; Kline, J L; Kyrala, G A; Landen, O L; Ma, T; MacFarlane, J J; MacKinnon, A J; Mancini, R C; McCrory, R L; Meezan, N B; Meyerhofer, D D; Nikroo, A; Park, H-S; Ralph, J; Remington, B A; Sangster, T C; Smalyuk, V A; Springer, P T; Town, R P J

2013-07-26

Mixing of plastic ablator material, doped with Cu and Ge dopants, deep into the hot spot of ignition-scale inertial confinement fusion implosions by hydrodynamic instabilities is diagnosed with x-ray spectroscopy on the National Ignition Facility. The amount of hot-spot mix mass is determined from the absolute brightness of the emergent Cu and Ge K-shell emission. The Cu and Ge dopants placed at different radial locations in the plastic ablator show the ablation-front hydrodynamic instability is primarily responsible for hot-spot mix. Low neutron yields and hot-spot mix mass between 34(-13,+50)  ng and 4000(-2970,+17 160)  ng are observed.

Hot-spot mix in ignition-scale inertial confinement fusion targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Regan, S. P.; Epstein, R.; Hammel, B. A.

Mixing of plastic ablator material, doped with Cu and Ge dopants, deep into the hot spot of ignition-scale inertial confinement fusion implosions by hydrodynamic instabilities is diagnosed with x-ray spectroscopy on the National Ignition Facility. The amount of hot-spot mix mass is determined from the absolute brightness of the emergent Cu and Ge K-shell emission. The Cu and Ge dopants placed at different radial locations in the plastic ablator show the ablation-front hydrodynamic instability is primarily responsible for hot-spot mix. As a result, low neutron yields and hot-spot mix mass between 34(–13,+50) ng and 4000(–2970,+17 160) ng are observed.

Hot-spot mix in ignition-scale inertial confinement fusion targets

DOE PAGES

Regan, S. P.; Epstein, R.; Hammel, B. A.; ...

2013-07-22

Mixing of plastic ablator material, doped with Cu and Ge dopants, deep into the hot spot of ignition-scale inertial confinement fusion implosions by hydrodynamic instabilities is diagnosed with x-ray spectroscopy on the National Ignition Facility. The amount of hot-spot mix mass is determined from the absolute brightness of the emergent Cu and Ge K-shell emission. The Cu and Ge dopants placed at different radial locations in the plastic ablator show the ablation-front hydrodynamic instability is primarily responsible for hot-spot mix. As a result, low neutron yields and hot-spot mix mass between 34(–13,+50) ng and 4000(–2970,+17 160) ng are observed.

A study on plastic wrinkling in thin-walled tube bending via an energy-based wrinkling prediction model

NASA Astrophysics Data System (ADS)

Li, H; Yang, H; Zhan, M

2009-04-01

Thin-walled tube bending is an advanced technology for producing precision bent tube parts in aerospace, aviation and automobiles, etc. With increasing demands of bending tubes with a larger tube diameter and a smaller bending radius, wrinkling instability is a critical issue to be solved urgently for improving the bending limit and forming quality in this process. In this study, by using the energy principle, combined with analytical and finite element (FE) numerical methods, an energy-based wrinkling prediction model for thin-walled tube bending is developed. A segment shell model is proposed to consider the critical wrinkling region, which captures the deformation features of the tube bending process. The dissipation energy created by the reaction forces at the tube-dies interface for restraining the compressive instability is also included in the prediction model, which can be numerically calculated via FE simulation. The validation of the model is performed and its physical significance is evaluated from various aspects. Then the plastic wrinkling behaviors in thin-walled tube bending are addressed. From the energy viewpoint, the effect of the basic parameters including the geometrical and material parameters on the onset of wrinkling is identified. In particular, the influence of multi-tools constraints such as clearance and friction at various interfaces on the wrinkling instability is obtained. The study provides instructive understanding of the plastic wrinkling instability and the model may be suitable for the wrinkling prediction of a doubly-curved shell in the complex forming process with contact conditions.

Finite plate thickness effects on the Rayleigh-Taylor instability in elastic-plastic materials

NASA Astrophysics Data System (ADS)

Polavarapu, Rinosh; Banerjee, Arindam

2017-11-01

The majority of theoretical studies have tackled the Rayleigh-Taylor instability (RTI) problem in solids using an infinitely thick plate. Recent theoretical studies by Piriz et al. (PRE 95, 053108, 2017) have explored finite thickness effects. We seek to validate this recent theoretical estimate experimentally using our rotating wheel RTI experiment in an accelerated elastic-plastic material. The test section consists of a container filled with air and mayonnaise (a non-Newtonian emulsion) with an initial perturbation between two materials. The plate thickness effects are studied by varying the depth of the soft-solid. A set of experiments is run by employing different initial conditions with different container dimensions. Additionally, the effect of acceleration rate (driving pressure rise time) on the instability threshold with reference to the finite thickness will also be inspected. Furthermore, the experimental results are compared to the analytical strength models related to finite thickness effects on RTI. Authors acknowledge financial support from DOE-SSAA Grant # DE-NA0003195 and LANL subcontract #370333.

Crack instability analysis methods for leak-before-break program in piping systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mattar Neto, M.; Maneschy, E.; Nobrega, P.G.B. da

1995-11-01

The instability evaluation of cracks in piping systems is a step that is considered when a high-energy line is investigated in a leak-before-break (LBB) program. Different approaches have been used to assess stability of cracks: (a) local flow stress (LFS); (b) limit load (LL); (c) elastic-plastic fracture mechanics (EPFM) as J-integral versus tearing modulus (J-T) analysis. The first two methods are used for high ductile materials, when it is assumed that remaining ligament of the cracked pipe section becomes fully plastic prior to crack extension. EPFM is considered for low ductile piping when the material reaches unstable ductile tearing priormore » to plastic collapse in the net section. In this paper the LFS, LL and EPFM J-T methodologies were applied to calculate failure loads in circumferential through-wall cracked pipes with different materials, geometries and loads. It presents a comparison among the results obtained from the above three formulations and also compares them with experimental data available in the literature.« less

Collisions of plastic and foam laser-driven foils studied by orthogonal x-ray imaging.

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Metzler, N.; Karasik, M.; Serlin, V.; Obenschain, S. P.; Schmitt, A. J.; Velikovich, A. L.; Zalesak, S. T.; Gardner, J. H.; Weaver, J.; Oh, J.; Harding, E. C.

2007-11-01

We report an experimental study of hydrodynamic Rayleigh-Taylor and Richtmyer-Meshkov-type instabilities developing at the material interface produced in double-foil collisions. Our double-foil targets consist of a plastic foil irradiated by the 4 ns Nike KrF laser pulse at ˜50 TW/cm^2 and accelerated toward a stationary plastic or foam foil. Either the rear side of the front foil or the front side of the rear foil is rippled. Orthogonal imaging, i. e., a simultaneous side-on and face-on x-ray radiography of the targets has been used in these experiments to observe the process of collision and the evolution of the areal mass amplitude modulation. Its observed evolution is similar to the case of the classical RM instability in finite thickness targets first studied by Y. Aglitsky et al., Phys. Plasmas 13, 80703 (2006). Our data are favorably compared with 1D and 2D simulation results.

Formulation and process considerations affecting the stability of solid dosage forms formulated with methacrylate copolymers.

PubMed

Petereit, H U; Weisbrod, W

1999-01-01

General considerations concerning the stability of coated dosage forms are discussed, in order to avoid predictable interactions which may cause long-term stability problems. As polymers themselves maintain a high chemical stability and a low reactivity, instability phenomena mainly have to be explained by interactions of low molecular weight substances or physical changes. Possible interactions of functional groups can be predicted easily and insulating subcoates are proper countermeasures. Impurities, remaining in the polymeric material from the manufacturing process, may accelerate the hydrolysis of sensitive drugs. Instabilities of coated dosage forms are mainly based on physical interactions, caused by improper formulations of coating suspensions (i.e. plasticizers or pigments) or the film coating process. Residual moisture or solvents, probably enclosed in the core and migrating over time, may increase the permeability of coatings, due to plasticizing effects. The functionality of coatings from aqueous dispersions is linked to coalescence of latex particles. Thus any incomplete film formation, caused by too high or too low coating temperatures, may result in high permeable coatings. During storage, preferably under stress conditions this process will continue and thus change the release profile. Therefore bed temperatures of 10-20 degrees C above MFT must ensure the formation of homogeneous polymer layers during the coating process. Stability test procedures and packaging materials also need to be adapted to the physicochemical properties of the dosage form, in order to get meaningful results in stability tests.

Numerical analysis of wellbore instability in gas hydrate formation during deep-water drilling

NASA Astrophysics Data System (ADS)

Zhang, Huaiwen; Cheng, Yuanfang; Li, Qingchao; Yan, Chuanliang; Han, Xiuting

2018-02-01

Gas hydrate formation may be encountered during deep-water drilling because of the large amount and wide distribution of gas hydrates under the shallow seabed of the South China Sea. Hydrates are extremely sensitive to temperature and pressure changes, and drilling through gas hydrate formation may cause dissociation of hydrates, accompanied by changes in wellbore temperatures, pore pressures, and stress states, thereby leading to wellbore plastic yield and wellbore instability. Considering the coupling effect of seepage of drilling fluid into gas hydrate formation, heat conduction between drilling fluid and formation, hydrate dissociation, and transformation of the formation framework, this study established a multi-field coupling mathematical model of the wellbore in the hydrate formation. Furthermore, the influences of drilling fluid temperatures, densities, and soaking time on the instability of hydrate formation were calculated and analyzed. Results show that the greater the temperature difference between the drilling fluid and hydrate formation is, the faster the hydrate dissociates, the wider the plastic dissociation range is, and the greater the failure width becomes. When the temperature difference is greater than 7°C, the maximum rate of plastic deformation around the wellbore is more than 10%, which is along the direction of the minimum horizontal in-situ stress and associated with instability and damage on the surrounding rock. The hydrate dissociation is insensitive to the variation of drilling fluid density, thereby implying that the change of the density of drilling fluids has a minimal effect on the hydrate dissociation. Drilling fluids that are absorbed into the hydrate formation result in fast dissociation at the initial stage. As time elapses, the hydrate dissociation slows down, but the risk of wellbore instability is aggravated due to the prolonged submersion in drilling fluids. For the sake of the stability of the wellbore in deep-water drilling through hydrate formation, the drilling fluid with low temperatures should be given priority. The drilling process should be kept under balanced pressures, and the drilling time should be shortened.

Prediction of plastic instabilities under thermo-mechanical loadings in tension and simple shear

NASA Astrophysics Data System (ADS)

Manach, P. Y.; Mansouri, L. F.; Thuillier, S.

2016-08-01

Plastic instabilities like Portevin-Le Châtelier were quite thoroughly investigated experimentally in tension, under a large range of strain rates and temperatures. Such instabilities are characterized both by a jerky flow and a localization of the strain in bands. Similar phenomena were also recorded for example in simple shear [1]. Modelling of this phenomenon is mainly performed at room temperature, taking into account the strain rate sensitivity, though an extension of the classical Estrin-Kubin-McCormick was proposed in the literature, by making some of the material parameters dependent on temperature. A similar approach is considered in this study, furthermore extended for anisotropic plasticity with Hill's 1948 yield criterion. Material parameters are identified at 4 different temperatures, ranging from room temperature up to 250°C. The identification procedure is split in 3 steps, related to the elasticity, the average stress level and the magnitude of the stress drops. The anisotropy is considered constant in this temperature range, as evidenced by experimental results [2]. The model is then used to investigate the temperature dependence of the critical strain, as well as its capability to represent the propagation of the bands. Numerical predictions of the instabilities in tension and simple shear at room temperature and up to 250°C are compared with experimental results [3]. In the case of simple shear, a monotonic loading followed by unloading and reloading in the reverse direction (“Bauschinger-type” test) is also considered, showing that (i) kinematic hardening should be taken into account to fully describe the transition at re-yielding (ii) the modelling of the critical strain has to be improved.

Modeling of coulpled deformation and permeability evolution during fault reactivation induced by deep underground injection of CO2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cappa, F.; Rutqvist, J.

2010-06-01

The interaction between mechanical deformation and fluid flow in fault zones gives rise to a host of coupled hydromechanical processes fundamental to fault instability, induced seismicity, and associated fluid migration. In this paper, we discuss these coupled processes in general and describe three modeling approaches that have been considered to analyze fluid flow and stress coupling in fault-instability processes. First, fault hydromechanical models were tested to investigate fault behavior using different mechanical modeling approaches, including slip interface and finite-thickness elements with isotropic or anisotropic elasto-plastic constitutive models. The results of this investigation showed that fault hydromechanical behavior can be appropriatelymore » represented with the least complex alternative, using a finite-thickness element and isotropic plasticity. We utilized this pragmatic approach coupled with a strain-permeability model to study hydromechanical effects on fault instability during deep underground injection of CO{sub 2}. We demonstrated how such a modeling approach can be applied to determine the likelihood of fault reactivation and to estimate the associated loss of CO{sub 2} from the injection zone. It is shown that shear-enhanced permeability initiated where the fault intersects the injection zone plays an important role in propagating fault instability and permeability enhancement through the overlying caprock.« less

Anisotropic Swelling and Fracture of Silicon Nanowires during Lithiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Xiao Hua; Zheng, He; Zhong, Li

2011-08-10

We report direct observation of an unexpected anisotropic swelling of Si nanowires during lithiation against either a solid electrolyte with a lithium counter-electrode or a liquid electrolyte with a LiCoO2 counter-electrode. Such anisotropic expansion is attributed to the interfacial processes of accommodating large volumetric strains at the lithiation reaction front that depend sensitively on the crystallographic orientation. This anisotropic swelling results in lithiated Si nanowires with a remarkable dumbbell-shaped cross section, which develops due to plastic flow and an ensuing necking instability that is induced by the tensile hoop stress buildup in the lithiated shell. The plasticity-driven morphological instabilities oftenmore » lead to fracture in lithiated nanowires, now captured in video. These results provide important insight into the battery degradation mechanisms.« less

Toward a definition of affective instability.

PubMed

Renaud, Suzane M; Zacchia, Camillo

2012-01-01

Affective instability is a psychophysiological symptom observed in some psychopathologies. It is a complex construct that encompasses (1) primary emotions, or affects, and secondary emotions, with each category having its own characteristics, amplitude, and duration, (2) rapid shifting from neutral or valenced affect to intense affect, and (3) dysfunctional modulation of emotions. Affective instability is often confused with mood lability, as in bipolar disorders, as well as with other terms. To clarify the concept, we searched databases for the term affective instability and read related articles on the topic. In this article we situate the term within the current affective nomenclature and human emotional experience, explore its psychophysiological features, and place it within the context of psychopathology. We explain why the term can potentially be confused with mood pathology and then define affective instability as an inherited temperamental trait modulated by developmental experience.

Thermomechanical coupling and dynamic strain ageing in ductile fracture

NASA Astrophysics Data System (ADS)

Delafosse, David

1995-01-01

This work is concerned with plastic deformation at the tip of a ductile tearing crack during propagation. Two kinds of effects are investigated: the thermomechanical coupling at the tip of a mobile ductile crack, and the influence of Dynamic Strain Aging (DSA) on ductile fracture. Three alloys are studied: a nickel based superalloy (N18), a soft carbon steel, and an Al-Li light alloy (2091). The experimental study of the thermo mechanical coupling effects by means of infrared thermography stresses the importance of plastic dissipation in the energy balance of ductile fracture. Numerical simulations involving plastic deformation as the only dissipation mechanism account for the main part of the measured heating. The effects of DSA on ductile tearing are investigated in the 2091 Al-Li alloy. Based on the strain rate/temperature dependence predicted by the standard model of DSA, an experimental procedure is set up for this purpose. Three main effects are evidenced. A maximum in tearing resistance is shown to be associated with the minimum of strain rate sensitivity. Through a simple model, this peak in tearing resistance is attributed to an increase in plastic dissipation as the strain rate sensitivity is decreased. Heterogenous plastic deformation is observed in the crack tip plastic zone. Comparison with uniaxial testing allows us to identify the observed strain heterogeneities as Portevin-Le Chatelier instabilities in the crack tip plastic zone. We perform a simplified numerical analysis of the effect of strain localization on crack tip screening. Finally, small crack propagation instabilities appear at temperatures slightly above that of the tearing resistance peak. These are interpreted as resulting from a positive feed-back between the local heating at the tip of a moving crack and the decrease in tearing resistance with increasing temperature.

Specificity of Affective Instability in Patients With Borderline Personality Disorder Compared to Posttraumatic Stress Disorder, Bulimia Nervosa, and Healthy Controls

PubMed Central

Santangelo, Philip; Mussgay, Lutz; Sawitzki, Günther; Trull, Timothy J.; Reinhard, Iris; Steil, Regina; Klein, Christoph; Bohus, Martin; Ebner-Priemer, Ulrich W.

2014-01-01

Affective instability is a core feature of borderline personality disorder (BPD). The use of advanced assessment methodologies and appropriate statistical analyses has led to consistent findings that indicate a heightened instability in patients with BPD compared with healthy controls. However, few studies have investigated the specificity of affective instability among patients with BPD with regard to relevant clinical control groups. In this study, 43 patients with BPD, 28 patients with posttraumatic stress disorder (PTSD), 20 patients with bulimia nervosa (BN), and 28 healthy controls carried e-diaries for 24 hours and were prompted to rate their momentary affective states approximately every 15 minutes while awake. To quantify instability, we used 3 state-of-the-art indices: multilevel models for squared successive differences (SSDs), multilevel models for probability of acute changes (PACs), and aggregated point-by-point changes (APPCs). Patients with BPD displayed heightened affective instability for emotional valence and distress compared with healthy controls, regardless of the specific instability indices. These results directly replicate earlier studies. However, affective instability did not seem to be specific to patients with BPD. With regard to SSDs, PACs, and APPCs, patients with PTSD or BN showed a similar heightened instability of affect (emotional valence and distress) to that of patients with BPD. Our results give raise to the discussion if affective instability is a transdiagnostic or a disorder-specific mechanism. Current evidence cannot answer this question, but investigating psychopathological mechanisms in everyday life across disorders is a promising approach to enhance validity and specificity of mental health diagnoses. PMID:24661176

Magneto-Rayleigh-Taylor instability in solid media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Y. B.; School of Physical Science and Technology, Lanzhou University, Lanzhou 73000; University of Chinese Academy of Sciences, Beijing 100049

2014-07-15

A linear analysis of the magneto-Rayleigh-Taylor instability at the interface between a Newtonian fluid and an elastic-plastic solid is performed by considering a uniform magnetic B{sup →}, parallel to the interface, which has diffused into the fluid but not into the solid. It is found that the magnetic field attributes elastic properties to the viscous fluid which enhance the stability region by stabilizing all the perturbation wavelengths shorter than λ{sub 0}∝B{sup 2} for any initial perturbation amplitude. Longer wavelengths are stabilized by the mechanical properties of the solid provided that the initial perturbation wavelength is smaller than a threshold valuemore » determined by the yield strength and the shear modulus of the solid. Beyond this threshold, the amplitude grows initially with a growth rate reduced by the solid strength properties. However, such properties do not affect the asymptotic growth rate which is only determined by the magnetic field and the fluid viscosity. The described physical situation intends to resemble some of the features present in recent experiments involving the magnetic shockless acceleration of flyers plates.« less

Hydrodynamic Instabilities in High-Energy-Density Settings

NASA Astrophysics Data System (ADS)

Smalyuk, Vladimir

2016-10-01

Our understanding of hydrodynamic instabilities, such as the Rayleigh-Taylor (RT), Richtmyer-Meshkov (RM), and Kelvin-Helmholtz (KH) instabilities, in high-energy-density (HED) settings over past two decades has progressed enormously. The range of conditions where hydrodynamic instabilities are experimentally observed now includes direct and indirect drive inertial confinement fusion (ICF) where surprises continue to emerge, linear and nonlinear regimes, classical interfaces vs. stabilized ablation fronts, tenuous ideal plasmas vs. high density Fermi degenerate plasmas, bulk fluid interpenetration vs. mixing down to the atomic level, in the presence of magnetic fields and/or intense radiation, and in solid state plastic flow at high pressures and strain rates. Regimes in ICF can involve extreme conditions of matter with temperatures up to kilovolts, densities of a thousand times solid densities, and time scales of nanoseconds. On the other hand, scaled conditions can be generated that map to exploding stars (supernovae) with length and time scales of millions of kilometers and hours to days or even years of instability evolution, planetary formation dynamics involving solid-state plastic flow which severely modifies the RT growth and continues to challenge reliable theoretical descriptions. This review will look broadly at progress in probing and understanding hydrodynamic instabilities in these very diverse HED settings, and then will examine a few cases in more depth to illustrate the detailed science involved. Experimental results on large-scale HED facilities such as the Omega, Nike, Gekko, and Shenguang lasers will be reviewed and the latest developments at the National Ignition Facility (NIF) and Z machine will be covered. Finally, current overarching questions and challenges will be summarized to motivate research directions for future. This work was performed under the auspices of the U.S. Department of Energy by LLNL under Contract DE-AC52-07NA27344.

Grain dynamics and plastic properties of highly refined materials

NASA Astrophysics Data System (ADS)

Lagos, Miguel; Retamal, César

2010-12-01

It has been shown that a grain boundary may undergo two competing classes of elastic instability when the in-plane shear stress exceeds the proper critical values. It may buckle acquiring a sinusoidal shape or may develop a periodic series of fissures, separating bands with a sigmoidal profile. The two instabilities lead to grain sliding, but the corresponding expressions relating the relative velocity between adjacent grains with stress do differ. The plastic properties for small strains were calculated for the two force laws, which we called force models A and B. A comparison of the theoretical results with published experimental data shows that model A, while giving predictions within the experimental uncertainties for a series of superplastic aluminium and titanium alloys, fails for Avesta 2304 steel. However, excellent results are obtained when model B is applied for this steel.

Crack Instability Predictions Using a Multi-Term Approach

NASA Technical Reports Server (NTRS)

Zanganeh, Mohammad; Forman, Royce G.

2015-01-01

Present crack instability analysis for fracture critical flight hardware is normally performed using a single parameter, K(sub C), fracture toughness value obtained from standard ASTM 2D geometry test specimens made from the appropriate material. These specimens do not sufficiently match the boundary conditions and the elastic-plastic constraint characteristics of the hardware component, and also, the crack instability of most commonly used aircraft and aerospace structural materials have some amount of stable crack growth before fracture which makes the normal use of a K(sub C) single parameter toughness value highly approximate. In the past, extensive studies have been conducted to improve the single parameter (K or J controlled) approaches by introducing parameters accounting for the geometry or in-plane constraint effects. Using 'J-integral' and 'A' parameter as a measure of constraint is one of the most accurate elastic-plastic crack solutions currently available. In this work the feasibility of the J-A approach for prediction of the crack instability was investigated first by ignoring the effects of stable crack growth i.e. using a critical J and A and second by considering the effects of stable crack growth using the corrected J-delta a using the 'A' parameter. A broad range of initial crack lengths and a wide range of specimen geometries including C(T), M(T), ESE(T), SE(T), Double Edge Crack (DEC), Three-Hole-Tension (THT) and NC (crack from a notch) manufactured from Al7075 were studied. Improvements in crack instability predictions were observed compared to the other methods available in the literature.

Strain Induced Elastomer Buckling Instability for Mechanical Measurements (SIEBIMM)

NASA Astrophysics Data System (ADS)

Harrison, Christopher; Stafford, Christopher M.; Amis, Eric J.; Karim, Alamgir

2003-03-01

We introduce a new technique (SIEBIMM) for high-throughput measurements of the mechanical properties of thin polymeric films. This technique relies upon a highly periodic strain-induced buckling instability that arises from a mismatch of the moduli of a relatively stiff polymer coating on a soft silicone sheet. The modulus-dependent buckling wavelength, typically 1-10 microns for 100 nm thick glassy films, is rapidly measured by conventional light scattering. The SIEBIMM-measured modulus is shown to agree with that measured by conventional Instron-like techniques. We directly show that the buckling instability is highly sinusoidal at low strain thereby insuring the suitability of simple mechanical analysis. Utilizing our expertise in preparing thickness gradients via flow coating, we demonstrate that the flexural rigidities of thin films having a wide range of thicknesses can be measured in minutes. By measuring the temporal decay of strain-induced diffraction peaks for plasticized coatings we show that this technique can evaluate viscoelastic properties, such as creep. We demonstrate SIEBIMM's capability with several academic and industrially-relevant polymeric systems, including polystyrene loaded with a wide range of plasticizer, a blend of block copolymers with polystyrene and polyisoprene blocks (Vector 4215 and 4411), and a thiolene-based ultraviolet curing adhesive.

Spreading of triboelectrically charged granular matter

NASA Astrophysics Data System (ADS)

Kumar, Deepak; Sane, A.; Gohil, Smita.; Bandaru, P. R.; Bhattacharya, S.; Ghosh, Shankar

2014-06-01

We report on the spreading of triboelectrically charged glass particles on an oppositely charged surface of a plastic cylindrical container in the presence of a constant mechanical agitation. The particles spread via sticking, as a monolayer on the cylinder's surface. Continued agitation initiates a sequence of instabilities of this monolayer, which first forms periodic wavy-stripe-shaped transverse density modulation in the monolayer and then ejects narrow and long particle-jets from the tips of these stripes. These jets finally coalesce laterally to form a homogeneous spreading front that is layered along the spreading direction. These remarkable growth patterns are related to a time evolving frictional drag between the moving charged glass particles and the countercharges on the plastic container. The results provide insight into the multiscale time-dependent tribolelectric processes and motivates further investigation into the microscopic causes of these macroscopic dynamical instabilities and spatial structures.

Mechanical instabilities in periodic porous elasto-plastic solids.

NASA Astrophysics Data System (ADS)

Singamaneni, Srikanth; Bertoldi, Katia; Chang, Sehoon; Jang, Ji-Hyun; Young, Seth; Thomas, Edwin; Boyce, Mary; Tsukruk, Vladimir

2009-03-01

We describe the transformation of the periodic microporous structures fabricated by interference lithography followed by their freezing below glass transition. Periodic porous microstructures subjected to internal compressive stresses can undergo sudden structural transformation at a critical strain. The pattern transformation of collapsed pores is caused by the stresses originated during the polymerization of acrylic acid (rubbery component) inside of cylindrical pores and the subsequent solvent evaporation in the organized microporous structure. The results of a non-linear numerical investigation confirm the critical role of the bifurcation of the periodic solid under compressive stresses. In striking contrast to the earlier observations of elastic instabilities in porous elastomeric solids, the elastic-plastic nature of the crosslinked periodic microstructure studied here provides for the ability to lock in the transformed pattern with complete relaxation of the internal stresses. By confining the polymerization of acrylic acid to localized porous areas complex microscopic periodic structures are obtained.

Filamentation due to the Weibel instability in two counterstreaming laser ablated plasmas

DOE PAGES

Dong, Quan -Li; Yuan, Dawei; Gao, Lan; ...

2016-05-01

Weibel-type filamentation instability was observed in the interaction of two counter streaming laser ablated plasma flows, which were supersonic, collisionless, and closely relevant to astrophysical conditions. The plasma flows were created by irradiating a pair of oppositely standing plastic (CH) foils with 1ns-pulsed laser beams of total energy of 1.7 kJ in two laser spots. Finally, with characteristics diagnosed in experiments, the calculated features of Weibel-type filaments are in good agreement with measurements.

A Multi-Parameter Approach for Calculating Crack Instability

NASA Technical Reports Server (NTRS)

Zanganeh, M.; Forman, R. G.

2014-01-01

An accurate fracture control analysis of spacecraft pressure systems, boosters, rocket hardware and other critical low-cycle fatigue cases where the fracture toughness highly impacts cycles to failure requires accurate knowledge of the material fracture toughness. However, applicability of the measured fracture toughness values using standard specimens and transferability of the values to crack instability analysis of the realistically complex structures is refutable. The commonly used single parameter Linear Elastic Fracture Mechanics (LEFM) approach which relies on the key assumption that the fracture toughness is a material property would result in inaccurate crack instability predictions. In the past years extensive studies have been conducted to improve the single parameter (K-controlled) LEFM by introducing parameters accounting for the geometry or in-plane constraint effects]. Despite the importance of the thickness (out-of-plane constraint) effects in fracture control problems, the literature is mainly limited to some empirical equations for scaling the fracture toughness data] and only few theoretically based developments can be found. In aerospace hardware where the structure might have only one life cycle and weight reduction is crucial, reducing the design margin of safety by decreasing the uncertainty involved in fracture toughness evaluations would result in lighter hardware. In such conditions LEFM would not suffice and an elastic-plastic analysis would be vital. Multi-parameter elastic plastic crack tip field quantifying developments combined with statistical methods] have been shown to have the potential to be used as a powerful tool for tackling such problems. However, these approaches have not been comprehensively scrutinized using experimental tests. Therefore, in this paper a multi-parameter elastic-plastic approach has been used to study the crack instability problem and the transferability issue by considering the effects of geometrical constraints as well as the thickness. The feasibility of the approach has been examined using a wide range of specimen geometries and thicknesses manufactured from 7075-T7351 aluminum alloy.

Further Experimental Investigations of the Richtmyer-Meshkov Instability

NASA Astrophysics Data System (ADS)

Miller, P. L.; Peyser, T. A.; Stry, P. E.; Logory, L. M.; Farley, D. R.

1996-11-01

We report on further experimental investigations of the Richtmyer-Meshkov instability from an initially nonlinear perturbation, conducted on the Nova laser. The experiments use a Nova hohlraum as a driver source for a strong shock in a miniature shock tube attached to the hohlraum. The shock tube contains brominated plastic and low-density carbon foam as the two working fluids, with a micro-machined sawtooth interface between them serving as the perturbation. The shock, upon crossing the interface, instigates the Richtmyer-Meshkov instability from the perturbation. The resulting growth of the mixing layer is diagnosed radiographically. We have previously reported upon a results from a single wavelength and amplitude of perturbation (T. A. Peyser et al., Phys. Rev. Lett.) 75, 2332 (1996).. A study of the effect of variations in amplitude and wavelength on the nonlinear growth of the instability will be discussed.

Ductile fracture of cylindrical vessels containing a large flaw

NASA Technical Reports Server (NTRS)

Erdogan, F.; Irwin, G. R.; Ratwani, M.

1976-01-01

The fracture process in pressurized cylindrical vessels containing a relatively large flaw is considered. The flaw is assumed to be a part-through or through meridional crack. The flaw geometry, the yield behavior of the material, and the internal pressure are assumed to be such that in the neighborhood of the flaw the cylinder wall undergoes large-scale plastic deformations. Thus, the problem falls outside the range of applicability of conventional brittle fracture theories. To study the problem, plasticity considerations are introduced into the shell theory through the assumptions of fully-yielded net ligaments using a plastic strip model. Then a ductile fracture criterion is developed which is based on the concept of net ligament plastic instability. A limited verification is attempted by comparing the theoretical predictions with some existing experimental results.

Ablative Rayleigh-Taylor and Richtmyer-Meshkov Instabilities in Laser-Accelerated Colliding Foils

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Metzler, N.; Karasik, M.; Serlin, V.; Weaver, J.; Obenschain, S. P.; Oh, J.; Schmitt, A. J.; Velikovich, A. L.; Zalesak, S. T.; Gardner, J. H.; Harding, E. C.

2008-11-01

In our experiments done on the Nike KrF laser, we study instability growth at shock-decelerated interfaces in planar colliding-foil experiments. We use streaked monochromatic (1.86 keV) x-ray face-on imaging diagnostics to measure the areal mass modulation growth caused by the instability. Higher x-ray energies up to 5.25 keV are used to follow the shock propagation as well as the 1D dynamics of the collision. While a laser-driven foil is accelerated towards the stationary low-density foam layer, an ablative RT instability develops. Having reached a high velocity, the foil hits the foam layer. The impact generates strong shocks in the plastic and in the foam. The reflected shock wave re-shocks the ablation front, its acceleration stops, and so does the observed RT growth. This is followed by areal mass oscillations due to the ablative RM instability and feedout mechanisms, of which the latter dominates.

Instability improvement of the subgrade soils by lime addition at Borg El-Arab, Alexandria, Egypt

NASA Astrophysics Data System (ADS)

El Shinawi, A.

2017-06-01

Subgrade soils can affect the stability of any construction elsewhere, instability problems were found at Borg El-Arab, Alexandria, Egypt. This paper investigates geoengineering properties of lime treated subgrade soils at Borg El-Arab. Basic laboratory tests, such as water content, wet and dry density, grain size, specific gravity and Atterberg limits, were performed for twenty-five samples. Moisture-density (compaction); California Bearing Ratio (CBR) and Unconfined Compression Strength (UCS) were conducted on treated and natural soils. The measured geotechnical parameters of the treated soil shows that 6% lime is good enough to stabilize the subgrade soils. It was found that by adding lime, samples shifted to coarser side, Atterberg limits values of the treated soil samples decreased and this will improve the soil to be more stable. On the other hand, Subgrade soils improved as a result of the bonding fine particles, cemented together to form larger size and reduce the plastiCity index which increase soils strength. The environmental scanning electron microscope (ESEM) is point to the presence of innovative aggregated cement materials which reduce the porosity and increase the strength as a long-term curing. Consequently, the mixture of soil with the lime has acceptable mechanical characteristics where, it composed of a high strength base or sub-base materials and this mixture considered as subgrade soil for stabilizations and mitigation the instability problems that found at Borg Al-Arab, Egypt.

Observed transition from Richtmyer-Meshkov jet formation through feedout oscillations to Rayleigh-Taylor instability in a laser target

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Karasik, M.; Velikovich, A. L.; Serlin, V.; Weaver, J. L.; Kessler, T. J.; Schmitt, A. J.; Obenschain, S. P.; Nikitin, S. P.; Metzler, N.; Oh, J.

2012-10-01

Experimental study of hydrodynamic perturbation evolution triggered by a laser-driven shock wave breakout at the free rippled rear surface of a plastic target is reported. We observed a transition between two qualitatively distinct types of perturbation evolution: jet formation at low shock pressure and areal mass oscillations at high shock pressure, which correspond respectively to high and low values of effective adiabatic index. The experiments were done on the KrF Nike laser facility with laser wavelength 248 nm and a 4 ns pulse. We varied the number of beams overlapped on the plastic target to change the ablative pressure driving the shock wave through the target: 36 beams produce pressure of ˜8 Mbar, whereas a single beam irradiation reduces the pressure to ˜0.7 Mbar. With the help of side-on monochromatic x-ray imaging, planar jets manifesting the development of the Richtmyer-Meshkov-type instability in a non-accelerated target are observed at sub-megabar shock pressure. As the shock pressure exceeds 1 Mbar, instead of jet formation an oscillatory rippled expansion wave is observed, followed by the ``feedout'' of the rear-surface perturbations to the ablation front and the development of the Rayleigh-Taylor instability, which breaks up the accelerated target.

Negative Affect Instability among Individuals with Comorbid Borderline Personality Disorder and Posttraumatic Stress Disorder

PubMed Central

Scheiderer, Emily M.; Wang, Ting; Tomko, Rachel L.; Wood, Phillip K.; Trull, Timothy J.

2015-01-01

Ecological momentary assessment (EMA; Stone & Shiffman, 1994) was utilized to examine affective instability (AI) in the daily lives of outpatients with borderline personality disorder (BPD; n=78) with and without posttraumatic stress disorder (PTSD). A psychiatric control group (n=50) composed of outpatients with major depressive disorder/dysthymia (MDD/DYS) was employed to compare across subgroups: BPD-only, BPD+PTSD, MDD/DYS-only, and MDD/DYS+PTSD. Compared to the BPD-only group, the BPD+PTSD group had significantly greater instability of fear and sadness, but did not significantly differ in instability of hostility or aggregate negative affect. This pattern of elevated instability of fear and sadness was not present—and, in fact, was reversed—in the MDD/DYS group. Results emphasize the importance of examining AI within the context of specific comorbidities and affect types. Treatment and research addressing AI in the context of BPD-PTSD comorbidity may benefit from a focus on fear and sadness as separate from hostility or general negative affect. PMID:26904388

Influence of deposited nanoparticles on the spall strength of metals under the action of picosecond pulses of shock compression

NASA Astrophysics Data System (ADS)

Ebel, A. A.; Mayer, A. E.

2018-01-01

Molecular dynamic simulations of the generation and propagation of shock pulses of picosecond duration initiated by nanoscale impactors, and their interaction with the rear surface is carried out for aluminum and copper. It is shown that the presence of deposited nanoparticles on the rear surface increases the threshold value of the impact intensity leading to the rear spallation. The interaction of a shock wave with nanoparticles leads to severe plastic deformation in the surface layer of the metal including nanoparticles. A part of the compression pulse energy is expended on the plastic deformation, which suppresses the spall fracture. Spallation threshold substantially increases at large diameters of deposited nanoparticles, but instability develops on the rear surface of the target, which is accompanied by ejection of droplets. The instability disrupts the integrity of the rear surface, though the loss of integrity occurs through the ejection of mass, rather than a spallation.

Experimental evidence of a bubble-merger regime for the Rayleigh-Taylor Instability at the ablation front

NASA Astrophysics Data System (ADS)

Casner, A.; Liberatore, S.; Masse, L.; Martinez, D.; Haan, S. W.; Kane, J.; Moore, A. S.; Seugling, R.; Farrell, M.; Giraldez, E.; Nikroo, A.; Smalyuk, V. A.; Remington, B. A.

2016-05-01

Under the Discovery Science program, the longer pulses and higher laser energies provided by the National Ignition Facility (NIF) have been harnessed to study, first time in indirect-drive, the highly nonlinear stage of the Rayleigh-Taylor Instability (RTI) at the ablation front. A planar plastic package with pre-imposed two-dimensional broadband modulations is accelerated for up to 12 ns by the x-ray drive of a gas-filled gold radiation cavity with a radiative temperature plateau at 175 eV. This extended tailored drive allows a distance traveled in excess of 1 mm for a 130 μm thick foil, a factor 3x larger than previously achieved on other laser facilities. As a consequence, we have measured the ablative RTI in transition from the weakly nonlinear stage up to the deep nonlinear stage for various initial conditions. A bubble merger regime has been observed and the ablative stabilization strength varied by changing the plastic dopant from iodine to germanium.

Instability-driven electromagnetic fields in coronal plasmas

DOE PAGES

Manuel, M. J.-E.; Li, C. K.; Seguin, F. H.; ...

2013-04-15

Filamentary electromagnetic fields previously observed in the coronae of laser-driven spherical targets [F. H. S eguin et al., Phys. Plasma. 19, 012701 (2012)] have been further investigated in laser irradiated plastic foils. Face-on proton-radiography provides an axial view of these filaments and shows coherent cellular structure regardless of initial foil-surface conditions. The observed cellular fields are shown to have an approximately constant scale size of 210 lm throughout the plasma evolution. A discussion of possible field-generation mechanisms is provided and it is demonstrated that the likely source of the cellular field structure is the magnetothermal instability. Using predicted temperature andmore » density profiles, the fastest growing modes of this instability were found to be slowly varying in time and consistent with the observed cellular size.« less

Observation of dual-mode, Kelvin-Helmholtz instability vortex merger in a compressible flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wan, W. C.; Malamud, Guy; Shimony, A.

Here, we report the first observations of Kelvin-Helmholtz vortices evolving from well-characterized, dual-mode initial conditions in a steady, supersonic flow. The results provide the first measurements of the instability's vortex merger rate and supplement data on the inhibition of the instability's growth rate in a compressible flow. These experimental data were obtained by sustaining a shockwave over a foam-plastic interface with a precision-machined seed perturbation. This technique produced a strong shear layer between two plasmas at high-energy-density conditions. The system was diagnosed using x-ray radiography and was well-reproduced using hydrodynamic simulations. Experimental measurements imply that we observed the anticipated vortexmore » merger rate and growth inhibition for supersonic shear flow.« less

Observation of dual-mode, Kelvin-Helmholtz instability vortex merger in a compressible flow

DOE PAGES

Wan, W. C.; Malamud, Guy; Shimony, A.; ...

2017-04-25

Here, we report the first observations of Kelvin-Helmholtz vortices evolving from well-characterized, dual-mode initial conditions in a steady, supersonic flow. The results provide the first measurements of the instability's vortex merger rate and supplement data on the inhibition of the instability's growth rate in a compressible flow. These experimental data were obtained by sustaining a shockwave over a foam-plastic interface with a precision-machined seed perturbation. This technique produced a strong shear layer between two plasmas at high-energy-density conditions. The system was diagnosed using x-ray radiography and was well-reproduced using hydrodynamic simulations. Experimental measurements imply that we observed the anticipated vortexmore » merger rate and growth inhibition for supersonic shear flow.« less

Progressive deformation of ultramafic rocks accompanied with deflection of layered structure and mylonitization culminating into a pseudotachylyte-bearing seismogenic fault - a field evidence of plastic instability

NASA Astrophysics Data System (ADS)

Ueda, T.; Obata, M.

2011-12-01

Plastic instability leading to rupture nucleation and propagetion (e.g. Hobbs et al.1986, Kelemen and Hirth, 2007) is an attractive hypothesis for deep earthquakes but lacked clear field evidences. 1D across-fault shear localization observed in some places (e.g. Jin et al.1998) is not clear if the deformation is directly related with seismicity. We present a clear field evidence of plastic instability as guided by pyroxenite/peridotite layering deflection structure (hereafter called LD structure, see figure) accompanied with mylonitization in spinel(Sp)-peridotite facies (P>~1GPa) in Balmuccia peridotite, Ivrea-Verbano Zone, Italy. The studied area contains abundant PST-bearing faults and N-S trending primary pyroxenite layers. Many faults in the area cut pyroxenite layers, but LD structure is found only in one place presented here. Many PSTs in the area have been (re)crystallized in Sp-peridotite facies, and have typically ultramylonitic texture (Ueda et al., 2008) with some injection veins. The fault with LD structure is situated in a fault system, which has two dominant attitudes with regional N-S extension. The shear strain of LD structure measured on outcrop surface is ~2.0. Near the fault, elongated Opx porphyroclasts (ellipses in figure) oblique to local layering are visible in peridotite. The dominant deformation textures are dynamic recrystallization in peridotite and kinking or undulatory extinction in pyroxenite. The mineral assemblages of the mylonite neoblast in the peridotite and the pyroxenite are Ol+Opx+Cpx+Sp+hornblende(Hbl), Cpx+Opx+Sp, respectively. Hbl typically occur only in neoblast. In the vicinity (several hundreds of micron) of the fault, dolomite(Dol) also occur in equilibrium with the assemblage above. The recrystallized grain sizes are 20-50 microns in peridotite and 10-30 microns in pyroxenite. The rarity of LD structure is consistent with general conception that deformation processes which lead to dynamic rupture initiation ought to be recorded in limited area on a resultant fault surface. The N-S extensional arrangement of the fault system including the fault of LD structure, the depth of PST (re)crystallization and mylonitization, all indicate that the rupture nucleation occurred in extensional tectonics (Souquiere and Fabbri , 2010). The occurrence of Dol in the vicinity of the PST fault suggests that this is the very place where plastic instability accompanied with fluid chemistry evolution (from H2O-rich to CO2-rich, caused by mylonitization and hydration) of Ueda et al. (2008.) had taken place.

Observation of parametric instabilities in the quarter critical density region driven by the Nike KrF laser

NASA Astrophysics Data System (ADS)

Weaver, J. L.; Oh, J.; Phillips, L.; Afeyan, B.; Seely, J.; Kehne, D.; Brown, C. M.; Obenschain, S. P.; Serlin, V.; Schmitt, A. J.; Feldman, U.; Lehmberg, R. H.; Mclean, E.; Manka, C.

2013-02-01

The krypton-fluoride (KrF) laser is an attractive choice for inertial confinement fusion due to its combination of short wavelength (λ =248 nm), large bandwidth (up to 3 THz), and superior beam smoothing by induced spatial incoherence. These qualities improve the overall hydrodynamics of directly driven pellet implosions and should allow use of increased laser intensity due to higher thresholds for laser plasma instabilities when compared to frequency tripled Nd:glass lasers (λ =351 nm). Here, we report the first observations of the two-plasmon decay instability using a KrF laser. The experiments utilized the Nike laser facility to irradiate solid plastic planar targets over a range of pulse lengths (0.35 ns≤τ≤1.25 ns) and intensities (up to 2×1015 W/cm2). Variation of the laser pulse created different combinations of electron temperature and electron density scale length. The observed onset of instability growth was consistent with the expected scaling that KrF lasers have a higher intensity threshold for instabilities in the quarter critical density region.

Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Lee, Y. -D.; Russell, D. A.; Orient, G. E.

1999-01-01

A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, delta J(sub eff) as the governing parameter. The methodology contains original and literature J and delta J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Lee, Y.-D.; Russell, D. A.; Orient, G. E.

1999-01-01

A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, (Delta)J(sub eff), as the governing parameter. The methodology contains original and literature J and (Delta)J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

The use of COD and plastic instability in crack propagation and arrest in shells

NASA Technical Reports Server (NTRS)

Erdogan, F.; Ratwani, M.

1974-01-01

The initiation, growth, and possible arrest of fracture in cylindrical shells containing initial defects are dealt with. For those defects which may be approximated by a part-through semi-elliptic surface crack which is sufficiently shallow so that part of the net ligament in the plane of the crack is still elastic, the existing flat plate solution is modified to take into account the shell curvature effect as well as the effect of the thickness and the small scale plastic deformations. The problem of large defects is then considered under the assumptions that the defect may be approximated by a relatively deep meridional part-through surface crack and the net ligament through the shell wall is fully yielded. The results given are based on an 8th order bending theory of shallow shells using a conventional plastic strip model to account for the plastic deformations around the crack border.

Intermittent hypoxia, respiratory plasticity and sleep apnea in humans: present knowledge and future investigations.

PubMed

Mateika, Jason H; Syed, Ziauddin

2013-09-15

This review examines the role that respiratory plasticity has in the maintenance of breathing stability during sleep in individuals with sleep apnea. The initial portion of the review considers the manner in which repetitive breathing events may be initiated in individuals with sleep apnea. Thereafter, the role that two forms of respiratory plasticity, progressive augmentation of the hypoxic ventilatory response and long-term facilitation of upper airway and respiratory muscle activity, might have in modifying breathing events in humans is examined. In this context, present knowledge regarding the initiation of respiratory plasticity in humans during wakefulness and sleep is addressed. Also, published findings which reveal that exposure to intermittent hypoxia promotes breathing instability, at least in part, because of progressive augmentation of the hypoxic ventilatory response and the absence of long-term facilitation, are considered. Next, future directions are presented and are focused on the manner in which forms of plasticity that stabilize breathing might be promoted while diminishing destabilizing forms, concurrently. These future directions will consider the potential role of circadian rhythms in the promotion of respiratory plasticity and the role of respiratory plasticity in enhancing established treatments for sleep apnea. Published by Elsevier B.V.

Identification and stabilization methods for problematic silt soils : a laboratory evaluation of modification and stabilization additives.

DOT National Transportation Integrated Search

2003-07-01

The instability and pumping response of non-plastic, high silt (and fine sand) soils was investigated. Common reagents, i.e., lime, lime-fly ash, Portland cement, and slag cement were included as admixtures with three high silt (and fine sand) soils....

Dynamic strain aging and plastic instabilities

NASA Astrophysics Data System (ADS)

Mesarovic, Sinisa Dj.

1995-05-01

A constitutive model proposed by McCormick [(1988) Theory of flow localization due to dynamic strain ageing. Acta. Metall.36, 3061-3067] based on dislocation-solute interaction and describing dynamic strain aging behavior, is analyzed for the simple loading case of uniaxial tension. The model is rate dependent and includes a time-varying state variable, representing the local concentration of the impurity atoms at dislocations. Stability of the system and its post-instability behavior are considered. The methods used include analytical and numerical stability and bifurcation analysis with a numerical continuation technique. Yield point behavior and serrated yielding are found to result for well defined intervals of temperature and strain rate. Serrated yielding emerges as a branch of periodic solutions of the relaxation oscillation type, similar to frictional stick-slip. The distinction between the temporal and spatial (loss of homogeneity of strain) instability is emphasized. It is found that a critical machine stiffness exists above which a purely temporal instability cannot occur. The results are compared to the available experimental data.

Plastic ingestion in aquatic-associated bird species in southern Portugal.

PubMed

Nicastro, Katy R; Lo Savio, Roberto; McQuaid, Christopher D; Madeira, Pedro; Valbusa, Ugo; Azevedo, Fábia; Casero, Maria; Lourenço, Carla; Zardi, Gerardo I

2018-01-01

Excessive use of plastics in daily life and the inappropriate disposal of plastic products are severely affecting wildlife species in both coastal and aquatic environments. Birds are top-predators, exposed to all threats affecting their environments, making them ideal sentinel organisms for monitoring ecosystems change. We set a baseline assessment of the prevalence of marine plastic litter affecting multi-species populations of aquatic birds in southern Portugal. By examining 160 stomach contents from 8 species of aquatic birds, we show that 22.5% were affected by plastic debris. Plastic was found in Ciconia ciconia, Larus fuscus and L. michahellis. Ciconia ciconia ingested the highest amount (number of items and total mass) of plastic debris. Polydimethylsiloxane (PDMS, silicones) was the most abundant polymer and was recorded only in C. ciconia. Plastic ingestion baseline data are of crucial importance to evaluate changes through time and among regions and to define management and conservation strategies. Copyright © 2017 Elsevier Ltd. All rights reserved.

Unstable plastic deformation of ultrafine-grained copper at 0.5 K

NASA Astrophysics Data System (ADS)

Isaev, N. V.; Grigorova, T. V.; Shumilin, S. E.; Polishchuk, S. S.; Davydenko, O. A.

2017-12-01

We investigate the relation between the strain-hardening rate and flow instability of polycrystalline Cu-OF deformed by tension at a constant rate in a liquid 3He atmosphere. The microstructure of the ultrafine-grained crystal, obtained by the equal-channel angular hydro-extrusion method, was varied by annealing at recovery and recrystallization temperatures and was monitored by x-ray diffraction. It is shown that that the flow instability, manifesting itself as macroscopic stress serrations on the tension curve, appears at a threshold tension sufficient for activation of a dynamic recovery that leads to a decrease of the strain-hardening coefficient. We discuss the effect of grain size and the initial dislocation density on the evolution of the dislocation structure that determines the scale and the statistical properties of the flow instability in the investigated crystals at low temperature.

Mitigation of hard x-ray background in backlit pinhole imagers

DOE PAGES

Fein, J. R.; Keiter, P. A.; Holloway, J. P.; ...

2016-09-16

Experiments were performed to mitigate the hard x-ray background commonly observed in backlit pinhole imagers. The material of the scaffold holding the primary backlighter foil was varied to reduce the laser-plasma instabilities responsible for hot electrons and resulting hard x-ray background. Radiographic measurements with image plates showed a factor of >25 decrease in x-rays between 30 and 67 keV when going from a plastic to Al or V scaffold. Here, a potential design using V scaffold offers a signal-to-background ratio of 6:1, a factor of 2 greater than using the bare plastic scaffold.

Colored plastic mulch microclimates affect strawberry fruit yield and quality

NASA Astrophysics Data System (ADS)

Shiukhy, Saeid; Raeini-Sarjaz, Mahmoud; Chalavi, Vida

2015-08-01

Significant reduction of strawberry ( Fragaria × ananassa, Duch.) fruit yield and quality, as a consequence of conventional cultivation method, is common in the Caspian Sea region, Iran. Recently, growers started using plastic mulches to overcome these shortcomings. Plastic mulches have different thermal and radiation properties and could affect strawberry fruit yield and quality. In the present study, the effect of different colored plastic mulches (black, red, and white) along with conventional practice was tested on yield and quality of strawberry Camarosa cultivar, in a completely randomized block design. Colored plastic mulches had highly significant effect on fruit weight, size, and phytochemical contents. In the most harvest times, mean fruit weight was significantly higher in red plastic relative to white and control treatments. Total fruit weight of plastic mulches was not significantly different, while all were statistically higher than that of control. Fruit size significantly increased over red plastic mulch. Total fruit numbers over plastic mulches were significantly higher than that of control treatment. The content of phenolic compounds was similar between treatments, while anthocyanin content, IC50 value, and flavonoid content significantly were affected by colored plastics. In conclusion, colored plastic mulches could affect strawberry fruit weight and quality through altering strawberry thermal and radiation environment.

Colored plastic mulch microclimates affect strawberry fruit yield and quality.

PubMed

Shiukhy, Saeid; Raeini-Sarjaz, Mahmoud; Chalavi, Vida

2015-08-01

Significant reduction of strawberry (Fragaria × ananassa, Duch.) fruit yield and quality, as a consequence of conventional cultivation method, is common in the Caspian Sea region, Iran. Recently, growers started using plastic mulches to overcome these shortcomings. Plastic mulches have different thermal and radiation properties and could affect strawberry fruit yield and quality. In the present study, the effect of different colored plastic mulches (black, red, and white) along with conventional practice was tested on yield and quality of strawberry Camarosa cultivar, in a completely randomized block design. Colored plastic mulches had highly significant effect on fruit weight, size, and phytochemical contents. In the most harvest times, mean fruit weight was significantly higher in red plastic relative to white and control treatments. Total fruit weight of plastic mulches was not significantly different, while all were statistically higher than that of control. Fruit size significantly increased over red plastic mulch. Total fruit numbers over plastic mulches were significantly higher than that of control treatment. The content of phenolic compounds was similar between treatments, while anthocyanin content, IC(50) value, and flavonoid content significantly were affected by colored plastics. In conclusion, colored plastic mulches could affect strawberry fruit weight and quality through altering strawberry thermal and radiation environment.

40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

Code of Federal Regulations, 2010 CFR

2010-07-01

... composites production facility is a new affected source or an existing affected source? 63.5795 Section 63... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source or...

Fillet Weld Stress Using Finite Element Methods

NASA Technical Reports Server (NTRS)

Lehnhoff, T. F.; Green, G. W.

1985-01-01

Average elastic Von Mises equivalent stresses were calculated along the throat of a single lap fillet weld. The average elastic stresses were compared to initial yield and to plastic instability conditions to modify conventional design formulas is presented. The factor is a linear function of the thicknesses of the parent plates attached by the fillet weld.

Dose dependence of true stress parameters in irradiated bcc, fcc, and hcp metals

NASA Astrophysics Data System (ADS)

Byun, T. S.

2007-04-01

The dose dependence of true stress parameters has been investigated for nuclear structural materials: A533B pressure vessel steels, modified 9Cr-1Mo and 9Cr-2WVTa ferritic martensitic steels, 316 and 316LN stainless steels, and Zircaloy-4. After irradiation to significant doses, these alloys show radiation-induced strengthening and often experience prompt necking at yield followed by large necking deformation. In the present work, the critical true stresses for deformation and fracture events, such as yield stress (YS), plastic instability stress (PIS), and true fracture stress (FS), were obtained from uniaxial tensile tests or calculated using a linear strain-hardening model for necking deformation. At low dose levels where no significant embrittlement was detected, the true fracture stress was nearly independent of dose. The plastic instability stress was also independent of dose before the critical dose-to-prompt-necking at yield was reached. A few bcc alloys such as ferritic martensitic steels experienced significant embrittlement at doses above ∼1 dpa; and the true fracture stress decreased with dose. The materials fractured before yield at or above 10 dpa.

Affective instability and the course of bipolar depression: results from the STEP-BD randomised controlled trial of psychosocial treatment

PubMed Central

Stange, Jonathan P.; Sylvia, Louisa G.; da Silva Magalhães, Pedro Vieira; Miklowitz, David J.; Otto, Michael W.; Frank, Ellen; Yim, Christine; Berk, Michael; Dougherty, Darin D.; Nierenberg, Andrew A.; Deckersbach, Thilo

2016-01-01

Background Little is known about predictors of recovery from bipolar depression. Aims We investigated affective instability (a pattern of frequent and large mood shifts over time) as a predictor of recovery from episodes of bipolar depression and as a moderator of response to psychosocial treatment for acute depression. Method A total of 252 out-patients with DSM-IV bipolar I or II disorder and who were depressed enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) and were randomised to one of three types of intensive psychotherapy for depression (n = 141) or a brief psychoeducational intervention (n = 111). All analyses were by intention-to-treat. Results Degree of instability of symptoms of depression and mania predicted a lower likelihood of recovery and longer time until recovery, independent of the concurrent effects of symptom severity. Affective instability did not moderate the effects of psychosocial treatment on recovery from depression. Conclusions Affective instability may be a clinically relevant characteristic that influences the course of bipolar depression. PMID:26795426

The roles of muscle stem cells in muscle injury, atrophy and hypertrophy.

PubMed

Fukada, So-Ichiro

2018-05-01

Skeletal muscle is composed of multinuclear cells called myofibers. Muscular dystrophy (a genetic muscle disorder) induces instability in the cell membrane of myofibers and eventually causes myofibre damage. Non-genetic muscle disorders, including sarcopenia, diabetes, bedridden immobility and cancer cachexia, lead to atrophy of myofibres. In contrast, resistance training induces myofibre hypertrophy. Thus, myofibres exhibit a plasticity that is strongly affected by both intrinsic and extrinsic factors. There is no doubt that muscle stem cells (MuSCs, also known as muscle satellite cells) are indispensable for muscle repair/regeneration, but their contributions to atrophy and hypertrophy are still controversial. The present review focuses on the relevance of MuSCs to (i) muscle diseases and (ii) hypertrophy. Further, this review addresses fundamental questions about MuSCs to clarify the onset or progression of these diseases and which might lead to development of a MuSC-based therapy.

Suppression of the Rayleigh Taylor instability and its implication for the impact ignition

NASA Astrophysics Data System (ADS)

Azechi, H.; Shiraga, H.; Nakai, M.; Shigemori, K.; Fujioka, S.; Sakaiya, T.; Tamari, Y.; Ohtani, K.; Murakami, M.; Sunahara, A.; Nagatomo, H.; Nishihara, K.; Miyanaga, N.; Izawa, Y.

2004-12-01

The Rayleigh Taylor (RT) instability with material ablation through an unstable interface is the key physics that determines the success or failure of inertial fusion energy (IFE) generation, as the RT instability potentially quenches ignition and burn by disintegrating the IFE target. We present two suppression schemes of the RT growth without significant degradation of the target density. The first scheme is to generate a double ablation structure in high-Z doped plastic targets. In addition to the electron ablation surface, a new ablation surface is created by x-ray radiation from the high-Z ions. Contrary to the previous thought, the electron ablation surface is almost completely stabilized by extremely high flow velocity. On the other hand, the RT instability on the radiative ablation surface is significantly moderated. The second is to enhance the nonlocal nature of the electron heat transport by illuminating the target with long wavelength laser light, whereas the high ablation pressure is generated by irradiating with short wavelength laser light. The significant suppression of the RT instability may increase the possibility of impact ignition which uses a high-velocity fuel colliding with a preformed main fuel.

Use of the Richtmyer-Meshkov Instability to Infer Yield Stress at High-Energy Densities

NASA Astrophysics Data System (ADS)

Dimonte, Guy; Terrones, G.; Cherne, F. J.; Germann, T. C.; Dupont, V.; Kadau, K.; Buttler, W. T.; Oro, D. M.; Morris, C.; Preston, D. L.

2011-12-01

We use the Richtmyer-Meshkov instability (RMI) at a metal-gas interface to infer the metal’s yield stress (Y) under shock loading and release. We first model how Y stabilizes the RMI using hydrodynamics simulations with a perfectly plastic constitutive relation for copper (Cu). The model is then tested with molecular dynamics (MD) of crystalline Cu by comparing the inferred Y from RMI simulations with direct stress-strain calculations, both with MD at the same conditions. Finally, new RMI experiments with solid Cu validate our simulation-based model and infer Y˜0.47GPa for a 36 GPa shock.

Phase behavior of colloidal dimers and hydrodynamic instabilities in binary mixtures

NASA Astrophysics Data System (ADS)

Milinkovic, K.

2013-05-01

We use computer simulations to study colloidal suspensions comprised of either bidisperse spherical particles or monodisperse dimer particles. The two main simulation techniques employed are a hybrid between molecular dynamics and stochastic rotation dynamics (MD-SRD), and a Monte Carlo (MC) algorithm. MD-SRD allows us to take Brownian motion and hydrodynamic interactions into account, while we use MC simulations to study equilibrium phase behavior. The first part of this thesis is dedicated to studying the Rayleigh-Taylor-like hydrodynamic instabilities which form in binary colloidal mixtures. Configurations with initially inhomogeneous distributions of colloidal species let to sediment in confinement will undergo the instability, and here we have studied the formation, evolution and the structural organization of the colloids within the instability as a function of the properties of the binary mixture. We found that the distribution of the colloids within the instability does not depend significantly on the composition of the mixtures, but does depend greatly on the relative magnitudes of the particle Peclet numbers. To follow the time evolution of the instability formation we calculated the spatial colloid velocity correlation functions, observing alternating regions in which the particle sedimentation velocities are correlated and anticorrelated. These observations are consistent with the network-like structures which are characteristic for Rayleigh-Taylor instabilities. We also calculated the growth rates of the unstable modes both from our simulation data and theoretically, finding good agreement between the obtained results. The second part of this thesis focuses on the phase behavior of monodisperse dimer systems. We first studied the phase behavior of hard snowman-shaped particles which consist of tangential hard spheres with different diameters. We used Monte Carlo simulations and free energy calculations to obtain the phase diagram as a function of the sphere diameter ratio, predicting stable isotropic fluid, plastic crystal and aperiodic crystalline phases. The crystalline phases found to be stable for a given diameter ratio at high densities correspond to the close packed structures of equimolar binary hard-sphere mixtures with the same diameter ratio. However, we also predict several crystal-crystal phase transitions, such that the best packed structures are stable at higher densities, while those with a higher degree of degeneracy are stable at lower densities. To explore the effects of degeneracy entropy on the phase behavior of dimer particles, we calculated the phase diagram of hard asymmetric dumbbells. These particles consist of two spheres with fixed diameters and varying center-to-center separation. We predicted stable isotropic fluid, plastic crystal, and periodic NaCl-based and both periodic and aperiodic CrB-based crystalline phases, and found that reducing the sphere separation results in the aperiodic crystalline phases of snowman-shaped particles becoming destabilized. Finally, we have also studied the phase behavior of dumbbell particles interacting with hard-core repulsive Yukawa potentials. We found that dumbbells with sufficiently long-ranged interactions crystallize spontaneously into plastic crystals in which the particle centers of mass are located on average on a BCC crystal lattice. The auto- and spatial orientational correlation functions reveal no significant hindrance of the particle rotations even for the shortest ranged interactions studied.

High Strain Rate and Shock-Induced Deformation in Metals

NASA Astrophysics Data System (ADS)

Ravelo, Ramon

2012-02-01

Large-scale non-equilibrium molecular Dynamics (MD) simulations are now commonly used to study material deformation at high strain rates (10^9-10^12 s-1). They can provide detailed information-- such as defect morphology, dislocation densities, and temperature and stress profiles, unavailable or hard to measure experimentally. Computational studies of shock-induced plasticity and melting in fcc and bcc single, mono-crystal metals, exhibit generic characteristics: high elastic limits, large directional anisotropies in the yield stress and pre-melting much below the equilibrium melt temperature for shock wave propagation along specific crystallographic directions. These generic features in the response of single crystals subjected to high strain rates of deformation can be explained from the changes in the energy landscape of the uniaxially compressed crystal lattice. For time scales relevant to dynamic shock loading, the directional-dependence of the yield strength in single crystals is shown to be due to the onset of instabilities in elastic-wave propagation velocities. The elastic-plastic transition threshold can accurately be predicted by a wave-propagation stability analysis. These strain-induced instabilities create incipient defect structures, which can be quite different from the ones, which characterize the long-time, asymptotic state of the compressed solid. With increase compression and strain rate, plastic deformation via extended defects gives way to amorphization associated with the loss in shear rigidity along specific deformation paths. The hot amorphous or (super-cooled liquid) metal re-crystallizes at rates, which depend on the temperature difference between the amorphous solid and the equilibrium melt line. This plastic-amorphous transition threshold can be computed from shear-waves stability analyses. Examples from selected fcc and bcc metals will be presented employing semi-empirical potentials of the embedded atom method (EAM) type as well as results from density functional theory calculations.

Mechanical conditions and modes of paraglacial deep-seated gravitational spreading in Valles Marineris, Mars

NASA Astrophysics Data System (ADS)

Makowska, Magdalena; Mège, Daniel; Gueydan, Frédéric; Chéry, Jean

2016-09-01

Deep-seated gravitational spreading (DSGS) affects the slopes of formerly glaciated mountain ridges. On Mars, DSGS has played a key role in shaping the landforms of the giant Valles Marineris troughs. Though less spectacular, DSGS is common in terrestrial orogens, where understanding its mechanics is critical in the light of the ongoing climate change because it is a potential source of catastrophic landslides in deglaciated valleys. We conducted parametric numerical studies in order to identify important factors responsible for DSGS initiation. DSGS models are computed using an elastoviscoplastic finite element code. Using ADELI's software, we reproduce topographic ridge spreading under the effect of valley unloading. Two types of spreading topographic ridges are investigated, homogeneous or with horizontal rheological layering. We find that gravitational instabilities are enhanced by high slopes, which increase gravitational stress, and low friction and cohesion, which decrease yield stress. In the unlayered ridge, instability is triggered by glacial unloading with plastic strain concentration inside the ridge and at the base of the high slopes. Vertical fractures develop in the upper part of the slope, potentially leading to fault scarps. Ridge homogeneity promotes a deformation mode controlled by uphill-facing normal faulting and basal bulging. In the second case, the ridge encompasses horizontal geological discontinuities that induce rock mass anisotropy. Discontinuity located at the base of the slope accumulates plastic strain, leading to the formation of a sliding plane evolving into a landslide. The presence of a weak layer at ridge base therefore promotes another slope deformation mode ending up with catastrophic failure. Mechanical conditions and slope height being equal, these conclusions can probably be extrapolated to Earth. Compared with Mars, DSGS on Earth is inhibited because terrestrial topographic gradients are lower than in Valles Marineris, an effect counterbalanced by increased gravitational stress, where the intensity of deformation is enhanced because of the Earth gravity potential.

Insights into the Streaming Instability in Protoplanetary Disks

NASA Astrophysics Data System (ADS)

Youdin, Andrew N.; Lin, Min-Kai; Li, Rixin

2017-10-01

The streaming instability is a leading mechanism to concentrate particles in protoplanetary disks, thereby triggering planetesimal formation. I will present recent analytical and numerical work on the origin of the streaming instability and its robustness. Our recent analytic work examines the origin of, and relationship between, a variety of drag-induced instabilities, including the streaming instability as well as secular gravitational instabilities, a drag instability driven by self-gravity. We show that drag instabilities are powered by a specific phase relationship between gas pressure and particle concentrations, which power the instability via pressure work. This mechanism is analogous to pulsating instabilities in stars. This mechanism differs qualitatively from other leading particle concentration mechanisms in pressure bumps and vortices. Our recent numerical work investigates the numerical robustness of non-linear particle clumping by the streaming instability, especially with regard to the location and boundary condition of vertical boundaries. We find that particle clumping is robust to these choices in boxes that are not too short. However, hydrodynamic activity away from the particle-dominated midplane is significantly affected by vertical boundary conditions. This activity affects the observationally significant lofting of small dust grains. We thus emphasize the need for larger scale simulations which connect disk surface layers, including outflowing winds, to the planet-forming midplane.

Evidence for a bubble-competition regime in indirectly driven ablative Rayleigh-Taylor instability experiments on the NIF.

PubMed

Martinez, D A; Smalyuk, V A; Kane, J O; Casner, A; Liberatore, S; Masse, L P

2015-05-29

We investigate on the National Ignition Facility the ablative Rayleigh-Taylor instability in the transition from weakly nonlinear to highly nonlinear regimes. A planar plastic package with preimposed two-dimensional broadband modulations is accelerated for up to 12 ns by the x-ray drive of a gas-filled Au radiation cavity with a radiative temperature plateau at 175 eV. This extended tailored drive allows a distance traveled in excess of 1 mm for a 130  μm thick foil. Measurements of the modulation optical density performed by x-ray radiography show that a bubble-merger regime for the Rayleigh-Taylor instability at an ablation front is achieved for the first time in indirect drive. The mutimode modulation amplitudes are in the nonlinear regime, grow beyond the Haan multimode saturation level, evolve toward the longer wavelengths, and show insensitivity to the initial conditions.

Effect of hydrogen on the mechanical properties of titanium and its alloys

NASA Technical Reports Server (NTRS)

Beck, F. H.

1975-01-01

Occluded hydrogen resulting from cathodic charging of commercially pure titanium and titanium alloys, Ti-8Al-1Mo-1V and Ti-6Al-4V, was shown to cause embrittlement of the alloys. Embrittlement was a function of the interstitial hydrogen content rather than the amount of precipitated titanium hydride. The effects of hydrogen concentration on the critical strain for plastic instability along pure shear directions was determined for alloys Ti-8Al-1Mo-1V and Ti-5Al-2.5Sn. Hydrogen, in concentrations below that necessary for spontaneous hydride precipitation, increased the strain necessary for instability formation or instability failure. The strain rate sensitivity also increased with increasing hydrogen concentration. The effect of hydrogen on slip and twinning was determined for titanium single crystals. The critical resolved shear stress for prism slip was increased and the critical resolved shear stress for twinning was decreased with increasing hydrogen concentration.

Evidence for a Bubble-Competition Regime in Indirectly Driven Ablative Rayleigh-Taylor Instability Experiments on the NIF

NASA Astrophysics Data System (ADS)

Martinez, D. A.; Smalyuk, V. A.; Kane, J. O.; Casner, A.; Liberatore, S.; Masse, L. P.

2015-05-01

We investigate on the National Ignition Facility the ablative Rayleigh-Taylor instability in the transition from weakly nonlinear to highly nonlinear regimes. A planar plastic package with preimposed two-dimensional broadband modulations is accelerated for up to 12 ns by the x-ray drive of a gas-filled Au radiation cavity with a radiative temperature plateau at 175 eV. This extended tailored drive allows a distance traveled in excess of 1 mm for a 130 μ m thick foil. Measurements of the modulation optical density performed by x-ray radiography show that a bubble-merger regime for the Rayleigh-Taylor instability at an ablation front is achieved for the first time in indirect drive. The mutimode modulation amplitudes are in the nonlinear regime, grow beyond the Haan multimode saturation level, evolve toward the longer wavelengths, and show insensitivity to the initial conditions.

[Built-in emergency brake in the balance system. Animal experiment research shows that a hierarchy of mechanisms compensate after acute peripheral vestibular decline].

PubMed

Magnusson, Anna K; Tham, Richard

A sudden unilateral loss of peripheral vestibular input results in the onset of acute dizziness and imbalance associated with spontaneous nystagmus, postural instability and nausea. Fortunately, these symptoms ameliorate rapidly, even without treatment, due to central nervous plastic changes which are collectively termed "vestibular compensation". This concept has become a widely accepted research model for studying lesion-induced plasticity. Recent research has dealt in particular with the plasticity of the medial vestibular nuclei that mediate the horizontal vestibulo-ocular reflex. Studies range from a cellular level in vitro to a functional level in vivo. Taken together, results from such studies have contributed greatly to what is known of vestibular compensation today. This article summarises evidence for several plasticity mechanisms that drive the recovery of spontaneous nystagmus, one of which is dependent on an endocrine stress-response. In the long run, such knowledge might influence the management and treatment of patients with balance disorders.

Effects of focal ankle joint cooling on unipedal static balance in individuals with and without chronic ankle instability.

PubMed

Kim, Kyung-Min; Hart, Joseph M; Saliba, Susan A; Hertel, Jay

2015-01-01

Application of cryotherapy over an injured joint has been shown to improve muscle function, yet it is unknown how ankle cryotherapy affects postural control. Our purpose was to determine the effects of a 20-min focal ankle joint cooling on unipedal static stance in individuals with and without chronic ankle instability (CAI). Fifteen young subjects with CAI (9 males, 6 females) and 15 healthy gender-matched controls participated. All subjects underwent two intervention sessions on different days in which they had a 1.5L plastic bag filled with either crushed ice (active treatment) or candy corn (sham) applied to the ankle. Unipedal stance with eyes closed for 10s were assessed with a forceplate before and after each intervention. Center of pressure (COP) data were used to compute 10 specific dependent measures including velocity, area, standard deviation (SD), and percent range of COP excursions, and mean and SD of time-to-boundary (TTB) minima in the anterior-posterior (AP) and mediolateral directions. For each measure a three-way (Group-Intervention-Time) repeated ANOVAs found no significant interactions and main effects involving intervention (all Ps > 0.05). There were group main effects found for mean velocity (F(1,28) = 6.46, P = .017), area (F(1,28) = 12.83, P = .001), and mean of TTB minima in the AP direction (F(1,28) = 5.19, P = .031) indicating that the CAI group demonstrated greater postural instability compared to the healthy group. Postural control of unipedal stance was not significantly altered following focal ankle joint cooling in groups both with and without CAI. Ankle joint cryotherapy was neither beneficial nor harmful to single leg balance. Copyright © 2014 Elsevier B.V. All rights reserved.

Small-Amplitude Richtmyer-Meshkov Instability at a Re-Shocked Material Interface

NASA Astrophysics Data System (ADS)

Velikovich, A. L.; Zalesak, S. T.; Metzler, N.; Aglitskiy, Y.

2008-11-01

We report an exact small-amplitude theory of the Richtmyer-Meshkov (RM) instability developing at a re-shocked material interface and favorably compare it to our simulations. The re-shock is seen to restart the classical RM instability growth from a larger initial amplitude, at a higher rate, and change its direction from heavy-to-light to light-to heavy and vice versa. Similarly, if a Rayleigh-Taylor (RT) unstable interface is strongly re-shocked from either the heavy or light fluid side, the fast RM growth is triggered. If a RT-unstable ablation front is re-shocked, it exhibits the ablative RM-instability, that is, low-frequency decaying oscillations [V. N. Goncharov, PRL 82, 2091 (1998); Y. Aglitskiy et al., PRL 87, 265001 (2001)]. This is predicted for colliding foil experiments on the Nike laser, where a RT-unstable ablation front is re-shocked by the strong shock wave produced in the collision of the laser-driven plastic foil with a stationary foam layer. The re-shock stops the acceleration and switches the perturbation evolution from the ablative RT to the ablative RM regime.

Longer reaction time of the fibularis longus muscle and reduced postural control in basketball players with functional ankle instability: A pilot study.

PubMed

Méndez-Rebolledo, Guillermo; Guzmán-Muñoz, Eduardo; Gatica-Rojas, Valeska; Zbinden-Foncea, Hermann

2015-08-01

Motor control evaluation in subjects with functional ankle instability is questionable when both ankles of the same subject are compared (affected vs non-affected). To compare the postural control and reaction time of ankle muscles among: basketball players with FAI (instability group), basketball players without FAI (non-instability group) and healthy non-basketball-playing participants (control group). Case-control study. Laboratory. Instability (n = 10), non-instability (n = 10), and control groups (n = 11). Centre of pressure variables (area, velocity and sway) were measured with a force platform. Reaction time of ankle muscles was measured via electromyography. A one-way ANOVA demonstrated that there were significant differences between the instability and non-instability groups in the fibularis longus (p < 0.001), fibularis brevis (p = 0.031) and tibialis anterior (p = 0.049) muscles. Repeated-measures ANOVA and post hoc analysis determined significant differences for the area between the instability and non-instability groups (p = 0.001). Basketball players with FAI have reduced postural control and longer reaction time of the fibularis and tibialis anterior muscles. Copyright © 2014 Elsevier Ltd. All rights reserved.

Hydrodynamic simulations of long-scale-length plasmas for two-plasmon-decay planar-target experiments on the NIF

NASA Astrophysics Data System (ADS)

Solodov, A. A.; Rosenberg, M. J.; Myatt, J. F.; Epstein, R.; Regan, S. P.; Seka, W.; Shaw, J.; Hohenberger, M.; Bates, J. W.; Moody, J. D.; Ralph, J. E.; Turnbull, D. P.; Barrios, M. A.

2016-05-01

The two-plasmon-decay (TPD) instability can be detrimental for direct-drive inertial confinement fusion because it generates high-energy electrons that can preheat the target, thereby reducing target performance. Hydrodynamic simulations to design a new experimental platform to investigate TPD and other laser-plasma instabilities relevant to direct-drive-ignition implosions at the National Ignition Facility are presented. The proposed experiments utilize planar plastic targets with an embedded Mo layer to characterize generation of hot electrons through Mo Kα fluorescence and hard x-ray emission. Different laser-irradiation geometries approximate conditions near both the equator and the pole of a polar-direct-drive implosion.

40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 12 2011-07-01 2009-07-01 true How do I know if my reinforced plastic... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source or...

40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 13 2013-07-01 2012-07-01 true How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 13 2014-07-01 2014-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 13 2012-07-01 2012-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

Self-Organization of Microcircuits in Networks of Spiking Neurons with Plastic Synapses.

PubMed

Ocker, Gabriel Koch; Litwin-Kumar, Ashok; Doiron, Brent

2015-08-01

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses connections between neurons depending on their joint spiking activity. Frequently, theoretical studies focus on how feedforward inputs drive plasticity to create this network structure. We study the complementary scenario of self-organized structure in a recurrent network, with spike timing-dependent plasticity driven by spontaneous dynamics. We develop a self-consistent theory for the evolution of network structure by combining fast spiking covariance with a slow evolution of synaptic weights. Through a finite-size expansion of network dynamics we obtain a low-dimensional set of nonlinear differential equations for the evolution of two-synapse connectivity motifs. With this theory in hand, we explore how the form of the plasticity rule drives the evolution of microcircuits in cortical networks. When potentiation and depression are in approximate balance, synaptic dynamics depend on weighted divergent, convergent, and chain motifs. For additive, Hebbian STDP these motif interactions create instabilities in synaptic dynamics that either promote or suppress the initial network structure. Our work provides a consistent theoretical framework for studying how spiking activity in recurrent networks interacts with synaptic plasticity to determine network structure.

Self-Organization of Microcircuits in Networks of Spiking Neurons with Plastic Synapses

PubMed Central

Ocker, Gabriel Koch; Litwin-Kumar, Ashok; Doiron, Brent

2015-01-01

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses connections between neurons depending on their joint spiking activity. Frequently, theoretical studies focus on how feedforward inputs drive plasticity to create this network structure. We study the complementary scenario of self-organized structure in a recurrent network, with spike timing-dependent plasticity driven by spontaneous dynamics. We develop a self-consistent theory for the evolution of network structure by combining fast spiking covariance with a slow evolution of synaptic weights. Through a finite-size expansion of network dynamics we obtain a low-dimensional set of nonlinear differential equations for the evolution of two-synapse connectivity motifs. With this theory in hand, we explore how the form of the plasticity rule drives the evolution of microcircuits in cortical networks. When potentiation and depression are in approximate balance, synaptic dynamics depend on weighted divergent, convergent, and chain motifs. For additive, Hebbian STDP these motif interactions create instabilities in synaptic dynamics that either promote or suppress the initial network structure. Our work provides a consistent theoretical framework for studying how spiking activity in recurrent networks interacts with synaptic plasticity to determine network structure. PMID:26291697

Plasticity of Nonneuronal Brain Tissue: Roles in Developmental Disorders

ERIC Educational Resources Information Center

Dong, Willie K.; Greenough, William T.

2004-01-01

Neuronal and nonneuronal plasticity are both affected by environmental and experiential factors. Remodeling of existing neurons induced by such factors has been observed throughout the brain, and includes alterations in dendritic field dimensions, synaptogenesis, and synaptic morphology. The brain loci affected by these plastic neuronal changes…

Using plastic instability to validate and test the strength law of a material under pressure

NASA Astrophysics Data System (ADS)

Bolis, Cyril; Counilh, Denis; Savale, Brice

2015-09-01

In dynamical experiments (pressures higher than 10 GPa, strain rate around 104-106 s-1), metals are classically described using an equation of state and a strength law which is usually set using data from compression or traction tests at low pressure (few MPa) and low strain rates (less than 103 s-1). In consequence, it needs to be extrapolated during dynamical experiments. Classical shock experiments do not allow a fine validation of the stress law due to the interaction with the equation of state. To achieve this aim, we propose to use a dedicated experiment. We started from the works of Barnes et al. (1974 and 1980) where plastic instabilities initiated by a sinusoidal perturbation at the surface of the metal develop with the pressure. We adapted this principle to a new shape of initial perturbation and realized several experiments. We will present the setup and its use on a simple material: gold. We will detail how the interpretation of the experiments, coupled with previous characterization experiments helps us to test the strength lax of this material at high pressure and high strain rate.

Equilibrium stability of a cylindrical body subject to the internal structure of the material and inelastic behaviour of the completely compressed matrix

NASA Astrophysics Data System (ADS)

Gotsev, D. V.; Perunov, N. S.; Sviridova, E. N.

2018-03-01

The mathematical model describing the stress-strain state of a cylindrical body under the uniform radial compression effect is constructed. The model of the material is the porous medium model. The compressed skeleton of the porous medium possesses hardening elastic-plastic properties. Deforming of the porous medium under the specified compressive loads is divided into two stages: elastic deforming of the porous medium and further elastic-plastic deforming of the material with completely compressed matrix. The analytical relations that define the fields of stress and displacement at each stage of the deforming are obtained. The influence of the porosity and other physical, mechanical and geometric parameters of the construction on the size of the plastic zone is evaluated. The question of the ground state equilibrium instability is investigated within the framework of the three-dimensional linearized relationships of the stability theory of deformed bodies.

A gradient enhanced plasticity-damage microplane model for concrete

NASA Astrophysics Data System (ADS)

Zreid, Imadeddin; Kaliske, Michael

2018-03-01

Computational modeling of concrete poses two main types of challenges. The first is the mathematical description of local response for such a heterogeneous material under all stress states, and the second is the stability and efficiency of the numerical implementation in finite element codes. The paper at hand presents a comprehensive approach addressing both issues. Adopting the microplane theory, a combined plasticity-damage model is formulated and regularized by an implicit gradient enhancement. The plasticity part introduces a new microplane smooth 3-surface cap yield function, which provides a stable numerical solution within an implicit finite element algorithm. The damage part utilizes a split, which can describe the transition of loading between tension and compression. Regularization of the model by the implicit gradient approach eliminates the mesh sensitivity and numerical instabilities. Identification methods for model parameters are proposed and several numerical examples of plain and reinforced concrete are carried out for illustration.

Effect of Surface Tension Anisotropy and Welding Parameters on Initial Instability Dynamics During Solidification: A Phase-Field Study

NASA Astrophysics Data System (ADS)

Yu, Fengyi; Wei, Yanhong

2018-05-01

The effects of surface tension anisotropy and welding parameters on initial instability dynamics during gas tungsten arc welding of an Al-alloy are investigated by a quantitative phase-field model. The results show that the surface tension anisotropy and welding parameters affect the initial instability dynamics in different ways during welding. The surface tension anisotropy does not influence the solute diffusion process but does affect the stability of the solid/liquid interface during solidification. The welding parameters affect the initial instability dynamics by varying the growth rate and thermal gradient. The incubation time decreases, and the initial wavelength remains stable as the welding speed increases. When welding power increases, the incubation time increases and the initial wavelength slightly increases. Experiments were performed for the same set of welding parameters used in modeling, and the results of the experiments and simulations were in good agreement.

Developmental instability of gynodioecious Teucrium lusitanicum

USGS Publications Warehouse

Alados, C.L.; Navarro, T.; Cabezudo, B.; Emlen, J.M.; Freeman, C.

1998-01-01

Developmental instability was assessed in two geographical races of Teucrium lusitanicum using morphometric measures of vegetative and reproductive structures. T. lusitanicum is a gynodioecious species. Male sterile (female) individuals showed greater developmental instability at all sites. Plants located inland had higher developmental instability of vegetative characters and lower developmental instability of reproductive characters than coastal plants. These results support the contentions that (1) developmental instability is affected more by the disruption of co-adapted gene complexes than by lower heterozygosity, and (2) different habitat characteristics result in the differential response of vegetative and reproductive structures.

Experimental research on the structural instability mechanism and the effect of multi-echelon support of deep roadways in a kilometre-deep well

PubMed Central

Peng, Rui; Zhao, Guangming; Li, Yingming; Zhu, Jianming

2018-01-01

We study the structural instability mechanism and effect of a multi-echelon support in very-deep roadways. We conduct a scale model test for analysing the structural failure mechanism and the effect of multi-echelon support of roadways under high horizontal stress. Mechanical bearing structures are classified according to their secondary stress distribution and the strength degradation of the surrounding rock after roadway excavation. A new method is proposed by partitioning the mechanical bearing structure of the surrounding rock into weak, key and main coupling bearing stratums. In the surrounding rock, the main bearing stratum is the plastic reshaping and flowing area. The weak bearing stratum is the peeling layer or the caving part. And the key bearing stratum is the shearing and yielding area. The structural fracture mechanism of roadways is considered in analysing the bearing structure instability of the surrounding rock, and multi-echelon support that considers the structural characteristics of roadway bearings is proposed. Results of the experimental study indicate that horizontal pressure seriously influences the stability of the surrounding rock, as indicated by extension of the weak bearing area and the transfer of the main and key bearing zones. The falling roof, rib spalling, and floor heave indicate the decline of the bearing capacity of surrounding rock, thereby causing roadway structural instability. Multi-echelon support is proposed according to the mechanical bearing structure of the surrounding rock without support. The redesigned support can reduce the scope of the weak bearing area and limit the transfer of the main and key bearing areas. Consequently, kilometre-deep roadway disasters, such as wedge roof caving, floor heave, and rib spalling, can be avoided to a certain degree, and plastic flow in the surrounding rock is relieved. The adverse effect of horizontal stress on the vault, spandrel and arch foot decreases. The stability of the soft rock surrounding the roadways is maintained. PMID:29447180

Generalization of the slip line field theory for temperature sensitive visco-plastic materials

NASA Astrophysics Data System (ADS)

Paesold, Martin; Peters, Max; Regenauer-Lieb, Klaus; Veveakis, Manolis; Bassom, Andrew

2015-04-01

Geological processes can be a combination of various effects such as heat production or consumption, chemical reactions or fluid flow. These individual effects are coupled to each other via feedbacks and the mathematical analysis becomes challenging due to these interdependencies. Here, we concentrate solely on thermo-mechanical coupling and a main result of this work is that the coupling can depend on material parameters and boundary conditions and the coupling is more or less pronounced depending on theses parameters. The transitions from weak to strong coupling can be studied in the context of a bifurcation analysis. classically, Material instabilities in solids are approached as material bifurcations of a rate-independent, isothermal, elasto-plastic solid. However, previous research has shown that temperature and deformation rate are important factors and are fully coupled with the mechanical deformation. Early experiments in steel revealed a distinct pattern of localized heat dissipation and plastic deformation known as heat lines. Further, earth materials, soils, rocks and ceramics are known to be greatly influenced by temperature with strain localization being strongly affected by thermal loading. In this work, we provide a theoretical framework for the evolution of plastic deformation for such coupled systems, with a two-pronged approach to the prediction of localized failure. First, slip line field theory is employed to predict the geometry of the failure patterns and second, failure criteria are derived from an energy bifurcation analysis. The bifurcation analysis is concerned with the local energy balance of a material and compares the effects of heat diffusion terms and heat production terms where the heat production is due to mechanical processes. Commonly, the heat is produced locally along the slip lines and if the heat production outweighs diffusion the material is locally weakened which eventually leads to failure. The effect of diffusion and heat production is captured by a dimensionless quantity, the Gruntfest number, and only if the Gruntfest number is larger than a critical value localized failure occurs. This critical Gruntfest number depends on boundary conditions such as temperature or pressure and hence this critical value gives rise to localization criteria. We find that the results of this approach agree with earlier contributions to the theory of plasticity but gives the advantage of a unified framework which might prove useful in numerical schemes for visco-plasticity.

The Everyday Emotional Experience of Adults with Major Depressive Disorder: Examining Emotional Instability, Inertia, and Reactivity

PubMed Central

Thompson, Renee J.; Mata, Jutta; Jaeggi, Susanne M.; Buschkuehl, Martin; Jonides, John; Gotlib, Ian H.

2013-01-01

Investigators have begun to examine the temporal dynamics of affect in individuals diagnosed with Major Depressive Disorder (MDD), focusing on instability, inertia, and reactivity of emotion. How these dynamics differ between individuals with MDD and healthy controls have not before been examined in a single study. In the present study, 53 adults with MDD and 53 healthy adults carried hand-held electronic devices for approximately seven days and were prompted randomly eight times per day to report their levels of current negative affect (NA), positive affect (PA), and the occurrence of significant events. In terms of NA, compared with healthy controls, depressed participants reported greater instability and greater reactivity to positive events, but comparable levels of inertia and reactivity to negative events. Neither average levels of NA nor NA reactivity to, frequency or intensity of, events accounted for the group difference in instability of NA. In terms of PA, the MDD and control groups did not differ significantly in their instability, inertia, or reactivity to positive or negative events. These findings highlight the importance of emotional instability in MDD, particularly with respect to NA, and contribute to a more nuanced understanding of the everyday emotional experiences of depressed individuals. PMID:22708886

Electron/ion whistler instabilities and magnetic noise bursts

NASA Technical Reports Server (NTRS)

Akimoto, K.; Gary, S. Peter; Omidi, N.

1987-01-01

Two whistler instabilities are investigated by means of the linear Vlasov dispersion equation. They are called the electron/ion parallel and oblique whistler instabilities, and are driven by electron/ion relative drifts along the magnetic field. It is demonstrated that the enhanced fluctuations from these instabilities can explain several properties of magnetic noise bursts in and near the plasma sheet in the presence of ion beams and/or field-aligned currents. At sufficiently high plasma beta, these instabilities may affect the current system in the magnetotail.

Contribution of Interpersonal Problems to Eating Disorder Psychopathology via Negative Affect in Treatment-seeking Men and Women: Testing the Validity of the Interpersonal Model in an Understudied Population.

PubMed

Ivanova, Iryna V; Tasca, Giorgio A; Proulx, Geneviève; Bissasda, Hany

2017-07-01

Research on the psychosocial correlates and theoretical frameworks of men presenting with eating disorders (ED) psychopathology is limited. This study compared treatment-seeking men and women in terms of their levels of interpersonal functioning (affiliation and dominance), regulation of negative emotions (negative affect and instability) and ED psychopathology. The study also investigated the validity of the interpersonal model of ED in men. Results from the cross-sectional data of 388 participants (137 men and 251 women) demonstrated that the structural models fit and that paths were invariant across men and women. There were significant indirect effects of interpersonal functioning on ED psychopathology, mediated through negative affect and instability, for both men and women. Negative affect and instability partially explain the relationship between interpersonal problems and ED psychopathology in treatment-seeking men and women. Current findings highlight the need to evaluate the validity of the model using longitudinal designs to test whether men and women are likely to benefit equally from interpersonal therapies for ED. Copyright © 2016 John Wiley & Sons, Ltd. Negative affect and instability mediated the relationship between interpersonal problems and eating disorder psychopathology for treatment-seeking men and women. There were no gender differences between levels of negative affect, emotional instability and interpersonal dysfunction, but women reported slightly higher eating concerns than men. Interpersonal model is a framework that is applicable to understanding and potentially treating men with eating disorders. Copyright © 2016 John Wiley & Sons, Ltd.

Analysis of Affective Instability in Ecological Momentary Assessment: Indices Using Successive Difference and Group Comparison via Multilevel Modeling

ERIC Educational Resources Information Center

Jahng, Seungmin; Wood, Phillip K.; Trull, Timothy J.

2008-01-01

Temporal instability of affect is a defining characteristic of psychological disorders such as borderline personality disorder (BPD) and mood cycling disorders. Ecological momentary assessment (EMA) enables researchers to directly assess such frequent and extreme fluctuations over time. The authors examined 4 operationalizations of such temporal…

Instability growth seeded by oxygen in CH shells on the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haan, S. W., E-mail: haan1@llnl.gov; Johnson, M. A.; Stadermann, M.

Fusion targets imploded on the National Ignition Facility are subject to hydrodynamic instabilities. These have generally been assumed to be seeded primarily by surface roughness, as existing work had suggested that internal inhomogeneity was small enough not to contribute significantly. New simulations presented here examine this in more detail, and consider modulations in internal oxygen content in CH plastic ablators. The oxygen is configured in a way motivated by measurement of oxygen in the shells. We find that plausible oxygen nonuniformity, motivated by target characterization experiments, seeds instability growth that is 3–5× bigger than expected from surface roughness. Pertinent existingmore » capsule characterization is discussed, which suggests the presence of internal modulations that could be oxygen at levels large enough to be the dominant seed for hydrodynamic instability growth. Oxygen-seeded growth is smaller for implosions driven by high-foot pulse shapes, consistent with the performance improvement seen with these pulse shapes. Growth is somewhat smaller for planned future pulse shapes that were optimized to minimize growth of surface ripples. A possible modified specification for oxygen modulations is discussed, which is about 1/5 of the current requirement.« less

Evidence for a Bubble-Competition Regime in Indirectly Driven Ablative Rayleigh-Taylor Instability Experiments on the NIF

DOE PAGES

Martinez, D. A.; Smalyuk, V. A.; Kane, J. O.; ...

2015-05-29

In this paper, we investigate on the National Ignition Facility the ablative Rayleigh-Taylor instability in the transition from weakly nonlinear to highly nonlinear regimes. A planar plastic package with preimposed two-dimensional broadband modulations is accelerated for up to 12 ns by the x-ray drive of a gas-filled Au radiation cavity with a radiative temperature plateau at 175 eV. This extended tailored drive allows a distance traveled in excess of 1 mm for a 130 μm thick foil. Measurements of the modulation optical density performed by x-ray radiography show that a bubble-merger regime for the Rayleigh-Taylor instability at an ablation frontmore » is achieved for the first time in indirect drive. Finally, the mutimode modulation amplitudes are in the nonlinear regime, grow beyond the Haan multimode saturation level, evolve toward the longer wavelengths, and show insensitivity to the initial conditions.« less

Drawing simulation by static implicit analysis with the artificial damping method

NASA Astrophysics Data System (ADS)

Oide, K.; Mihara, Y.; Kobayashi, T.; Takizawa, H.; Amaishi, T.; Umezu, Y.

2016-08-01

Wrinkling during draw is typically a local instability problem. When the structural instability is localized, there will be a local transfer of strain energy from one part of the structure to neighboring parts, and global solution methods, which is typically represented by the arc length method, may not work. So, this type of problems has to be solved either dynamically or with the artificial damping. On the other hand, the essential nature of the buckling behavior can be regarded as a static problem, even though it may be possible to raise some side issues due to the inertia effect. In this study, we traced the local buckling behavior of anisotropic elasto-plastic thin shells in Numisheet2014 BM4 using the artificial damping method.

Genetic stability and instability of the cis-acting control element of the 5' untranslated region of the poliovirus RNA.

PubMed

Agol, V I

1993-01-01

The poliovirus genome exhibits tremendous plasticity, which is particularly evident when mutations diminishing the growth potential are introduced into the genome. An amazing variability can be observed even among the genomes derived from a single plaque. Not less amazing is the stability of the viral RNA sequences, which could be revealed, for example, upon the analysis of populations of a given viral strain separated by many cycles of reproduction in different laboratories but under standard conditions. This stability is obviously due to very strong selection for the "fit" phenotype. Implications of both the stability and instability of the poliovirus genome for the design, production and use of live poliovirus vaccines are briefly discussed.

Cultural diversity, economic development and societal instability.

PubMed

Nettle, Daniel; Grace, James B; Choisy, Marc; Cornell, Howard V; Guégan, Jean-François; Hochberg, Michael E

2007-09-26

Social scientists have suggested that cultural diversity in a nation leads to societal instability. However, societal instability may be affected not only by within-nation or alpha diversity, but also diversity between a nation and its neighbours or beta diversity. It is also necessary to distinguish different domains of diversity, namely linguistic, ethnic and religious, and to distinguish between the direct effects of diversity on societal instability, and effects that are mediated by economic conditions. We assembled a large cross-national dataset with information on alpha and beta cultural diversity, economic conditions, and indices of societal instability. Structural equation modeling was used to evaluate the direct and indirect effects of cultural diversity on economics and societal stability. Results show that different types and domains of diversity have interacting effects. As previously documented, linguistic alpha diversity has a negative effect on economic performance, and we show that it is largely through this economic mechanism that it affects societal instability. For beta diversity, the higher the linguistic diversity among nations in a region, the less stable the nation. But, religious beta diversity has the opposite effect, reducing instability, particularly in the presence of high linguistic diversity. Within-nation linguistic diversity is associated with reduced economic performance, which, in turn, increases societal instability. Nations which differ linguistically from their neighbors are also less stable. However, religious diversity between neighboring nations has the opposite effect, decreasing societal instability.

Cultural diversity, economic development and societal instability

USGS Publications Warehouse

Nettle, D.; Grace, J.B.; Choisy, M.; Cornell, H.V.; Guegan, J.-F.; Hochberg, M.E.

2007-01-01

Background. Social scientists have suggested that cultural diversity in a nation leads to societal instability. However, societal instability may be affected not only by within-nation on ?? diversity, but also diversity between a nation and its neighbours or ?? diversity. It is also necessary to distinguish different domains of diversity, namely linguistic, ethnic and religious, and to distinguish between the direct effects of diversity on societal instability, and effects that are mediated by economic conditions. Methodology/Principal Findings. We assembled a large cross-national dataset with information on ?? and ?? cultural diversity, economic conditions, and indices of societal instability. Structural equation modeling was used to evaluate the direct and indirect effects of cultural diversity on economics and societal stability. Results show that different type and domains of diversity have interacting effects. As previously documented, linguistic ?? diversity has a negative effect on economic performance, and we show that it is largely through this economic mechanism that it affects societal instability. For ?? diversity, the higher the linguistic diversity among nations in a region, the less stable the nation. But, religious ?? diversity has the opposite effect, reducing instability, particularly in the presence of high linguistic diversity. Conclusions. Within-nation linguistic diversity is associated with reduced economic performance, which, in turn, increases societal instability. Nations which differ linguistically from their neighbors are also less stable. However, religious diversity between, neighboring nations has the opposite effect, decreasing societal instability.

Experimental Evidence for the Los Alamos Proton Storage Ring Beam Instability

NASA Astrophysics Data System (ADS)

Plum, M.; Fitzgerald, D. H.; Macek, R.; Sander, O.; Thiessen, H. A.; Wang, T. S.; Wilkinson, C.

1997-05-01

Although the exact instability mechanism at the Proton Storage Ring (PSR) has not yet been conclusively identified, the evidence gathered to date is consistent with an e-p instability. We have recently acquired new data which shows that clearing electrodes significantly affect the instability threshold. A set of comprehensive measurements is also planned for the first months of 1997. In this paper we will present our latest data.

Sources and sinks of plastic debris in estuaries: A conceptual model integrating biological, physical and chemical distribution mechanisms.

PubMed

Vermeiren, Peter; Muñoz, Cynthia C; Ikejima, Kou

2016-12-15

Micro- and macroplastic accumulation threatens estuaries worldwide because of the often dense human populations, diverse plastic inputs and high potential for plastic degradation and storage in these ecosystems. Nonetheless, our understanding of plastic sources and sinks remains limited. We designed conceptual models of the local and estuary-wide transport of plastics. We identify processes affecting the position of plastics in the water column; processes related to the mixing of fresh and salt water; and processes resulting from the influences of wind, topography, and organism-plastic interactions. The models identify gaps in the spatial context of plastic-organisms interactions, the chemical behavior of plastics in estuaries, effects of wind on plastic suspension-deposition cycles, and the relative importance of processes affecting the position in the water column. When interpreted in the context of current understanding, sinks with high management potential can be identified. However, source-sink patterns vary among estuary types and with local scale processes. Copyright © 2016 Elsevier Ltd. All rights reserved.

Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis

PubMed Central

Liu, Han-Hsuan

2016-01-01

Fragile X mental retardation protein (FMRP) is thought to regulate neuronal plasticity by limiting dendritic protein synthesis, but direct demonstration of a requirement for FMRP control of local protein synthesis during behavioral plasticity is lacking. Here we tested whether FMRP knockdown in Xenopus optic tectum affects local protein synthesis in vivo and whether FMRP knockdown affects protein synthesis-dependent visual avoidance behavioral plasticity. We tagged newly synthesized proteins by incorporation of the noncanonical amino acid azidohomoalanine and visualized them with fluorescent noncanonical amino acid tagging (FUNCAT). Visual conditioning and FMRP knockdown produce similar increases in FUNCAT in tectal neuropil. Induction of visual conditioning-dependent behavioral plasticity occurs normally in FMRP knockdown animals, but plasticity degrades over 24 h. These results indicate that FMRP affects visual conditioning-induced local protein synthesis and is required to maintain the visual conditioning-induced behavioral plasticity. SIGNIFICANCE STATEMENT Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. Exaggerated dendritic protein synthesis resulting from loss of fragile X mental retardation protein (FMRP) is thought to underlie cognitive deficits in FXS, but no direct evidence has demonstrated that FMRP-regulated dendritic protein synthesis affects behavioral plasticity in intact animals. Xenopus tadpoles exhibit a visual avoidance behavior that improves with visual conditioning in a protein synthesis-dependent manner. We showed that FMRP knockdown and visual conditioning dramatically increase protein synthesis in neuronal processes. Furthermore, induction of visual conditioning-dependent behavioral plasticity occurs normally after FMRP knockdown, but performance rapidly deteriorated in the absence of FMRP. These studies show that FMRP negatively regulates local protein synthesis and is required to maintain visual conditioning-induced behavioral plasticity in vivo. PMID:27383604

Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis.

PubMed

Liu, Han-Hsuan; Cline, Hollis T

2016-07-06

Fragile X mental retardation protein (FMRP) is thought to regulate neuronal plasticity by limiting dendritic protein synthesis, but direct demonstration of a requirement for FMRP control of local protein synthesis during behavioral plasticity is lacking. Here we tested whether FMRP knockdown in Xenopus optic tectum affects local protein synthesis in vivo and whether FMRP knockdown affects protein synthesis-dependent visual avoidance behavioral plasticity. We tagged newly synthesized proteins by incorporation of the noncanonical amino acid azidohomoalanine and visualized them with fluorescent noncanonical amino acid tagging (FUNCAT). Visual conditioning and FMRP knockdown produce similar increases in FUNCAT in tectal neuropil. Induction of visual conditioning-dependent behavioral plasticity occurs normally in FMRP knockdown animals, but plasticity degrades over 24 h. These results indicate that FMRP affects visual conditioning-induced local protein synthesis and is required to maintain the visual conditioning-induced behavioral plasticity. Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. Exaggerated dendritic protein synthesis resulting from loss of fragile X mental retardation protein (FMRP) is thought to underlie cognitive deficits in FXS, but no direct evidence has demonstrated that FMRP-regulated dendritic protein synthesis affects behavioral plasticity in intact animals. Xenopus tadpoles exhibit a visual avoidance behavior that improves with visual conditioning in a protein synthesis-dependent manner. We showed that FMRP knockdown and visual conditioning dramatically increase protein synthesis in neuronal processes. Furthermore, induction of visual conditioning-dependent behavioral plasticity occurs normally after FMRP knockdown, but performance rapidly deteriorated in the absence of FMRP. These studies show that FMRP negatively regulates local protein synthesis and is required to maintain visual conditioning-induced behavioral plasticity in vivo. Copyright © 2016 the authors 0270-6474/16/367325-15$15.00/0.

Semitendinosus Tendon Transfer Associated With Distal Alignment for Patella Alta in a Patient With Recurrent Dislocations.

PubMed

Calderazzi, Filippo; Pellegrini, Andrea; Coviello, Gianluca; Groppi, Giulia; Ceccarelli, Francesco

2015-10-01

Patellofemoral instability is characterized by pain during normal daily activities and frequent dislocation events. In the reported case, an adolescent girl, aged 15 years, affected by left patellofemoral instability, underwent surgery with a double technique comprising tibial tubercle distalization and medial patellofemoral ligament reconstruction. In case of patella alta associated with patellofemoral instability, surgical treatment should focus on medial patellofemoral ligament repair and on recurrent instability prevention.

Addendum to the User Manual for NASGRO Elastic-Plastic Fracture Mechanics Software Module

NASA Technical Reports Server (NTRS)

Gregg, M. Wayne (Technical Monitor); Chell, Graham; Gardner, Brian

2003-01-01

The elastic-plastic fracture mechanics modules in NASGRO have been enhanced by the addition of of the following: new J-integral solutions based on the reference stress method and finite element solutions; the extension of the critical crack and critical load modules for cracks with two degrees of freedom that tear and failure by ductile instability; the addition of a proof test analysis module that includes safe life analysis, calculates proof loads, and determines the flaw screening 1 capability for a given proof load; the addition of a tear-fatigue module for ductile materials that simultaneously tear and extend by fatigue; and a multiple cycle proof test module for estimating service reliability following a proof test.

Study of plastic strain localization mechanisms caused by nonequilibrium transitions in mesodefect ensembles under high-speed loading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sokovikov, Mikhail, E-mail: sokovikov@icmm.ru; Chudinov, Vasiliy; Bilalov, Dmitry

2015-10-27

The behavior of specimens dynamically loaded during split Hopkinson (Kolsky) bar tests in a regime close to simple shear conditions was studied. The lateral surface of the specimens was investigated in-situ using a high-speed infrared camera CEDIP Silver 450M. The temperature field distribution obtained at different time allowed one to trace the evolution of plastic strain localization. The process of target perforation involving plug formation and ejection was examined using a high-speed infrared camera and a VISAR velocity measurement system. The microstructure of tested specimens was analyzed using an optical interferometer-profiler and a scanning electron microscope. The development of plasticmore » shear instability regions has been simulated numerically.« less

[Plastic surgery of the thoracic wall as a method of thoracic wall reconstruction after complete surgical wound disintegration after sternotomy].

PubMed

Hájek, T; Jirásek, K; Urban, M; Straka, Z

1998-12-01

During the period between January 1996 and July 1998 in our department 1920 patients were operated on account of heart disease from median sternotomy. In 17 patients, i.e. in 0.9% during the early postoperative period the surgical wound disintegrated incl. dehiscence of the sternum and the development of postoperative mediastinitis. In 14 of these patients the authors reconstructed the defect of the thoracic wall by their own modification of Jurkiewicz plastic operation using the pectoral muscles. One patient from this group died, in the remaining 13 patients the wound healed without deformity of the chest and without signs of instability, without restriction of movement and function.

Plastic waste associated with disease on coral reefs.

PubMed

Lamb, Joleah B; Willis, Bette L; Fiorenza, Evan A; Couch, Courtney S; Howard, Robert; Rader, Douglas N; True, James D; Kelly, Lisa A; Ahmad, Awaludinnoer; Jompa, Jamaluddin; Harvell, C Drew

2018-01-26

Plastic waste can promote microbial colonization by pathogens implicated in outbreaks of disease in the ocean. We assessed the influence of plastic waste on disease risk in 124,000 reef-building corals from 159 reefs in the Asia-Pacific region. The likelihood of disease increases from 4% to 89% when corals are in contact with plastic. Structurally complex corals are eight times more likely to be affected by plastic, suggesting that microhabitats for reef-associated organisms and valuable fisheries will be disproportionately affected. Plastic levels on coral reefs correspond to estimates of terrestrial mismanaged plastic waste entering the ocean. We estimate that 11.1 billion plastic items are entangled on coral reefs across the Asia-Pacific and project this number to increase 40% by 2025. Plastic waste management is critical for reducing diseases that threaten ecosystem health and human livelihoods. Copyright © 2018, The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Settling-driven gravitational instabilities associated with volcanic clouds: new insights from experimental investigations

NASA Astrophysics Data System (ADS)

Scollo, Simona; Bonadonna, Costanza; Manzella, Irene

2017-06-01

Downward propagating instabilities are often observed at the bottom of volcanic plumes and clouds. These instabilities generate fingers that enhance the sedimentation of fine ash. Despite their potential influence on tephra dispersal and deposition, their dynamics is not entirely understood, undermining the accuracy of volcanic ash transport and dispersal models. Here, we present new laboratory experiments that investigate the effects of particle size, composition and concentration on finger generation and dynamics. The experimental set-up consists of a Plexiglas tank equipped with a removable plastic sheet that separates two different layers. The lower layer is a solution of water and sugar, initially denser than the upper layer, which consists of water and particles. Particles in the experiments include glass beads as well as andesitic, rhyolitic and basaltic volcanic ash. During the experiments, we removed the horizontal plastic sheet separating the two fluids. Particles were illuminated with a laser and filmed with a HD camera; particle image velocimetry (PIV) is used to analyse finger dynamics. Results show that both the number and the downward advance speed of fingers increase with particle concentration in the upper layer, while finger speed increases with particle size but is independent of particle composition. An increase in particle concentration and turbulence is estimated to take place inside the fingers, which could promote aggregation in subaerial fallout events. Finally, finger number, finger speed and particle concentration were observed to decrease with time after the formation of fingers. A similar pattern could occur in volcanic clouds when the mass supply from the eruptive vent is reduced. Observed evolution of the experiments through time also indicates that there must be a threshold of fine ash concentration and mass eruption rate below which fingers do not form; this is also confirmed by field observations.

Studies on Equatorial Shock Formation During Plasmaspheric Refilling

NASA Technical Reports Server (NTRS)

Singh, Nagendra

1995-01-01

During the grant period from August 1, 1994 to October 31, 1995 we have continued to investigate the effects of plasma wave instabilities on the early stage plasmaspheric refilling. Since ion beams are the primary feature of the interhemispheric plasma flows during the early stage refilling, ion-beam driven instabilities and associated waves are of primary interest. The major findings of this research are briefly summarized here. After a systematic examination of the relevant plasma instabilities, we realized that when the interhemispheric plasma flows begin to interpenetrate at the equator, the most relevant plasma instability is the electrostatic ion cyclotron wave instability. Only at later stages the ion-acoustic instability may be affecting the plasma flow. An interesting property of the electrostatic ion cyclotron wave is that it heats ions perpendicular to the magnetic field. When the ions in the field-aligned flows are transversely heated, they are trapped in the magnetic flux tube, thus affecting the refilling process. The eic wave instability is a microprocess with scale length of the order of ion Larmor radius and the corresponding time scale is the ion cyclotron period. We have attempted to tackle the problem for the plasmaspheric refilling by incorporating the effects of eic wave instability on the mesoscale plasma flow when the properties of the latter exceeds the critical conditions for the former. We have compared the results on refilling from the model with and without the eic instability effects.

Cultural Diversity, Economic Development and Societal Instability

PubMed Central

Nettle, Daniel; Grace, James B.; Choisy, Marc; Cornell, Howard V.; Guégan, Jean-François; Hochberg, Michael E.

2007-01-01

Background Social scientists have suggested that cultural diversity in a nation leads to societal instability. However, societal instability may be affected not only by within-nation or α diversity, but also diversity between a nation and its neighbours or β diversity. It is also necessary to distinguish different domains of diversity, namely linguistic, ethnic and religious, and to distinguish between the direct effects of diversity on societal instability, and effects that are mediated by economic conditions. Methodology/Principal Findings We assembled a large cross-national dataset with information on α and β cultural diversity, economic conditions, and indices of societal instability. Structural equation modeling was used to evaluate the direct and indirect effects of cultural diversity on economics and societal stability. Results show that different types and domains of diversity have interacting effects. As previously documented, linguistic α diversity has a negative effect on economic performance, and we show that it is largely through this economic mechanism that it affects societal instability. For β diversity, the higher the linguistic diversity among nations in a region, the less stable the nation. But, religious β diversity has the opposite effect, reducing instability, particularly in the presence of high linguistic diversity. Conclusions Within-nation linguistic diversity is associated with reduced economic performance, which, in turn, increases societal instability. Nations which differ linguistically from their neighbors are also less stable. However, religious diversity between neighboring nations has the opposite effect, decreasing societal instability. PMID:17895970

Supersonic, shockwave-driven hydrodynamic instability experiments at OMEGA-EP

NASA Astrophysics Data System (ADS)

Wan, Willow

2016-10-01

Hydrodynamic instabilities play a dominant role in the transport of mass, momentum, and energy in nearly every plasma environment, governing the dynamics of natural and engineering systems such as solar convective zones, magnetospheric boundaries, and fusion experiments. In past decades, limitations in our understanding of hydrodynamic instabilities have led to discrepancies between observations and predictions. Since then, significant improvements have been made to our available experimental techniques, diagnostics, and simulation capabilities. Here, we present a novel experimental platform that can sustain a steady, supersonic flow across a precision-machined, well-characterized material interface for unprecedented durations We applied this platform to a series of Kelvin-Helmholtz instability experiments. The Kelvin-Helmholtz instability generates vortical structures and turbulence at an interface with shear flow. In a supersonic flow, the growth rate is inhibited and the instability structure is altered. The data were obtained at the OMEGA-EP facility by firing three laser beams in sequence to produce a 12 kJ, 28 ns stitched laser pulse. The ablation pressure sustained a steady shockwave for 70 ns over a foam-plastic, single-mode or dual-mode interface. A spherical crystal imager was used to measure the evolution of these modulations with high-resolution x-ray radiography using Cu Kα radiation at 8.0 keV. The observed structure was reproduced with 2D hydrodynamic simulations. Supported by the U.S. DOE, through NNSA Grants DE-NA0002956 (SSAA) and DE-NA0002719 (NLUF), by the LLE under DE-NA0001944, and by the LLNL under subcontract B614207 to DE-AC52-07NA27344.

Experimental Observation of Nonlinear Mode Coupling In the Ablative Rayleigh-Taylor Instability on the NIF

NASA Astrophysics Data System (ADS)

Martinez, David

2015-11-01

We investigate on the National Ignition Facility (NIF) the ablative Rayleigh-Taylor (RT) instability in the transition from linear to highly nonlinear regimes. This work is part of the Discovery Science Program on NIF and of particular importance to indirect-drive inertial confinement fusion (ICF) where careful attention to the form of the rise to final peak drive is calculated to prevent the RT instability from shredding the ablator in-flight and leading to ablator mixing into the cold fuel. The growth of the ablative RT instability was investigated using a planar plastic foil with pre-imposed two-dimensional broadband modulations and diagnosed using x-ray radiography. The foil was accelerated for 12ns by the x-ray drive created in a gas-filled Au radiation cavity with a radiative temperature plateau at 175 eV. The dependence on initial conditions was investigated by systematically changing the modulation amplitude, ablator material and the modulation pattern. For each of these cases bubble mergers were observed and the nonlinear evolution of the RT instability showed insensitivity to the initial conditions. This experiment provides critical data needed to validate current theories on the ablative RT instability for indirect drive that relies on the ablative stabilization of short-scale modulations for ICF ignition. This paper will compare the experimental data to the current nonlinear theories. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344. Lawrence Livermore National Security, LLC.

Temporal associations between affective instability and dysregulated eating behavior in bulimia nervosa.

PubMed

Berner, Laura A; Crosby, Ross D; Cao, Li; Engel, Scott G; Lavender, Jason M; Mitchell, James E; Wonderlich, Stephen A

2017-09-01

Prior research suggests that the construct of emotional instability may be salient to bulimia nervosa (BN), but no study to date has used ecological momentary assessment (EMA) to examine its temporal association with binge eating and purging. In the current study, 133 women with DSM-IV BN used portable digital devices to provide multiple daily negative affect (NA) and positive affect (PA) ratings and record eating disorder behaviors over 2 weeks. Two state-of-the art indices quantified affective instability: probability of acute change (PAC), which represents the likelihood of extreme affective increases, and mean squared successive difference (MSSD), which represents average change over successive recordings. For extreme affective change, results revealed that on bulimic behavior days, extreme NA increases were less likely after bulimic behaviors than before them, and extreme increases in PA were more likely after bulimic behaviors than during the same time period on non-bulimic behavior days. However, average NA instability (i.e., MSSD) was (a) greater on bulimic behavior days than non-bulimic behavior days, (b) greater after bulimic behaviors than during the same time period on non-bulimic behavior days, and (c) greater after bulimic behaviors than before them. Results lend support to the notion that bulimic behaviors are negatively reinforcing (i.e., via post-behavior acute affective changes), but also indicate that these behaviors may exacerbate overall affective dysregulation. These findings may improve understanding of BN maintenance and inform the development of novel interventions or refinement of existing treatments. Copyright © 2017 Elsevier Ltd. All rights reserved.

Viscous instabilities in the q-vortex at large swirl numbers

NASA Astrophysics Data System (ADS)

Fabre, David; Jacquin, Laurent

2002-11-01

This comunication deals with the temporal stability of the q-vortex trailing line vortex model. We describe a family of viscous instabilities existing in a range of parameters which is usually assumed to be stable, namely large swirl parameters (q>1.5) and large Reynolds numbers. These instabilities affect negative azimuthal wavenumbers (m < 0) and take the form of centre-modes (i.e. with a structure concentrated along the vortex centerline). They are related to a family of viscous modes described by Stewartson, Ng & Brown (1988) in swirling Poiseuille flow, and are the temporal counterparts of weakly amplified spatial modes recently computed by Olendraru & Sellier (2002). These instabilities are studied numerically using an original and highly accurate Chebyshev collocation method, which allows a mapping of the unstable regions up to Rey 10^6 and q 7. Our results indicate that in the limit of very large Reynolds numbers, trailing vortices are affected by this kind of instabilities whatever the value of the swirl number.

A comparison of hydro-instabilities in CH, HDC, and beryllium ablators on NIF

NASA Astrophysics Data System (ADS)

Smalyuk, V. A.; Robey, H. F.; Ali, S.; Berzak Hopkins, L. F.; Casey, D. T.; Celliers, P. M.; Clark, D. S.; Felker, S. J.; Field, J. E.; Haan, S. W.; Hammel, B. A.; Hsing, W. W.; Kroll, J. J.; Landen, O. L.; Lepape, S.; Macphee, A. G.; Martinez, D.; Milovich, J.; Nikroo, A.; Pickworth, L.; Stadermann, M.; Weber, C. R.; Kline, J.; Loomis, E.; Yi, A.

2017-10-01

A comparison of the hydrodynamic growth in plastic, high-density carbon, and beryllium ablators will be presented in indirect-drive implosions on National Ignition Facility. This comparison is based on experimentally measured instabilities in all phases of implosions for the three ablators. The 2-D and 3-D perturbations were measured at the ablation-surface with the Hydrodynamic Growth Radiography platform. In the deceleration phase of implosions, innovative self-emission and ``self-backlight'' techniques were used. Results of the 3-D perturbation growth including engineering features will also be presented for convergence up to 20 and compared for the three ablators. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

Negative emotionality across diagnostic models: RDoC, DSM-5 Section III, and FFM.

PubMed

Gore, Whitney L; Widiger, Thomas A

2018-03-01

The research domain criteria (RDoC) were established in an effort to explore underlying dimensions that cut across many existing disorders and to provide an alternative to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). One purpose of the present study was to suggest a potential alignment of RDoC negative valence with 2 other dimensional models of negative emotionality: five-factor model (FFM) neuroticism and the DSM-5 Section III negative affectivity. A second purpose of the study, though, was to compare their coverage of negative emotionality, more specifically with respect to affective instability. Participants were adult community residents (N = 90) currently in mental health treatment. Participants received self-report measures of RDoC negative valence, FFM neuroticism, and DSM-5 Section III negative affectivity, along with measures of affective instability, borderline personality disorder, and impairment. Findings suggested that RDoC negative valence is commensurate with FFM neuroticism and DSM-5 Section III negative affectivity, and it would be beneficial if it was expanded to include affective instability. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Hidden instabilities in the Ti:sapphire Kerr lens mode-locked laser.

PubMed

Kovalsky, M G; Hnilo, A A; González Inchauspe, C M

1999-11-15

It is experimentally shown that pulse-to-pulse instabilities in the output of Kerr lens mode-locked Ti:sapphire lasers are usual and that they can affect some of the pulse variables (e.g., the spot size) and not others (e.g., pulse duration and energy). These instabilities are not detectable in the averaged signals (such as the autocorrelation of the pulse) that are customarily used for controlling the laser. But, if they are present but are disregarded, these instabilities have undesirable consequences in almost any application. A simple way to detect and eliminate the instabilities is described.

Leaf-trait plasticity and species vulnerability to climate change in a Mongolian steppe.

PubMed

Liancourt, Pierre; Boldgiv, Bazartseren; Song, Daniel S; Spence, Laura A; Helliker, Brent R; Petraitis, Peter S; Casper, Brenda B

2015-09-01

Climate change is expected to modify plant assemblages in ways that will have major consequences for ecosystem functions. How climate change will affect community composition will depend on how individual species respond, which is likely related to interspecific differences in functional traits. The extraordinary plasticity of some plant traits is typically neglected in assessing how climate change will affect different species. In the Mongolian steppe, we examined whether leaf functional traits under ambient conditions and whether plasticity in these traits under altered climate could explain climate-induced biomass responses in 12 co-occurring plant species. We experimentally created three probable climate change scenarios and used a model selection procedure to determine the set of baseline traits or plasticity values that best explained biomass response. Under all climate change scenarios, plasticity for at least one leaf trait correlated with change in species performance, while functional leaf-trait values in ambient conditions did not. We demonstrate that trait plasticity could play a critical role in vulnerability of species to a rapidly changing environment. Plasticity should be considered when examining how climate change will affect plant performance, species' niche spaces, and ecological processes that depend on plant community composition. © 2015 John Wiley & Sons Ltd.

Observations of shear flows in high-energy-density plasmas

NASA Astrophysics Data System (ADS)

Harding, Eric C.

The research discussed in this thesis represents work toward the demonstration of experimental designs for creating a Kelvin-Helmholtz (KH) unstable shear layer in a high-energy-density (HED) plasma. Such plasmas are formed by irradiating materials with several kilo-Joules of laser light over a few nanoseconds, and are defined as having an internal pressure greater than one-million atmospheres. Similar plasmas exist in laboratory fusion experiments and in the astrophysical environment. The KH instability is a fundamental fluid instability that arises when strong velocity gradients exist at the interface between two fluids. The KH instability is important because it drives the mixing of fluids and initiates the transition to turbulence in the flow. Until now, the evolution of the KH instability has remained relatively unexplored in the HED regime This thesis presents the observations and analysis of two novel experiments carried out using two separate laser facilities. The first experiment used 1.4 kJ from the Nike laser to generate a supersonic flow of Al plasma over a low-density, rippled foam surface. The Al flow interacted with the foam and created distinct features that resulted from compressible effects. In this experiment there is little evidence of the KH instability. Nevertheless, this experimental design has perhaps pioneered a new method for generating a supersonic shear flow that has the potential to produce the KH instability if more laser energy is applied. The second experiment was performed on the Omega laser. In this case 4.3 kJ of laser energy drove a blast wave along a rippled foam/plastic interface. In response to the vorticity deposited and the shear flow established by the blast wave, the interface rolls up into large vorticies characteristic of the KH instability. The Omega experiment was the first HED experiment to capture the evolution of the KH instability.

Pyrolysis of plastic waste for liquid fuel production as prospective energy resource

NASA Astrophysics Data System (ADS)

Sharuddin, S. D. A.; Abnisa, F.; Daud, W. M. A. W.; Aroua, M. K.

2018-03-01

The worldwide plastic generation expanded over years because of the variety applications of plastics in numerous sectors that caused the accumulation of plastic waste in the landfill. The growing of plastics demand definitely affected the petroleum resources availability as non-renewable fossil fuel since plastics were the petroleum-based material. A few options that have been considered for plastic waste management were recycling and energy recovery technique. Nevertheless, several obstacles of recycling technique such as the needs of sorting process that was labour intensive and water pollution that lessened the process sustainability. As a result, the plastic waste conversion into energy was developed through innovation advancement and extensive research. Since plastics were part of petroleum, the oil produced through the pyrolysis process was said to have high calorific value that could be used as an alternative fuel. This paper reviewed the thermal and catalytic degradation of plastics through pyrolysis process and the key factors that affected the final end product, for instance, oil, gaseous and char. Additionally, the liquid fuel properties and a discussion on several perspectives regarding the optimization of the liquid oil yield for every plastic were also included in this paper.

Potential media influence on the high incidence of medical disputes from the perspective of plastic surgeons.

PubMed

Chen, Chiehfeng; Lin, Ching-Feng; Chen, Cha-Chun; Chiu, Shih-Feng; Shih, Fuh-Yuan; Lyu, Shu-Yu; Lee, Ming-Been

2017-08-01

The main purpose of this study is to investigate the prevalence of medical disputes among plastic surgeons in Taiwan and to elucidate their perspectives regarding the influence of medical litigation media coverage on the physician-patient relationship. A self-administered questionnaire was distributed among plastic surgeons attending a series of continuing education training lectures organized by the Taiwan Society of Plastic Surgery in 2015. Of the 109 respondents, over a third (36.4%) had previously experienced a medical dispute. The vast majority of both physicians who had medical disputes (77.1%) and those who did not (72.1%) felt that the media tends to be supportive of patients in their reporting, and 37.1% of all plastic surgeons felt that the media always portrays the patient as a victim. Respondents who experienced medical disputes in this study felt that the top five leading causes of the high incidence of medical disputes were patient disappointment with procedure results (81.1%), insufficient patient psychological preparation or emotional instability (61.7%), inadequate risk communication on the part of the physician (64.9%), patient uneasiness with the procedure or perception of carelessness (60.6%), and insufficient physician training or incorrect medical evaluation (57.4%). Over a third of the respondents had previously experienced a medical dispute. This study highlights the perception among plastic surgeons that the media reporting of medical disputes and medical litigation is biased in favor of the patients, with 37.1% of the plastic surgeons surveyed opining that patients are always cast as victims. Copyright © 2017. Published by Elsevier B.V.

Plasticized chitosan/polyolefin films produced by extrusion.

PubMed

Matet, Marie; Heuzey, Marie-Claude; Ajji, Abdellah; Sarazin, Pierre

2015-03-06

Plasticized chitosan and polyethylene blends were produced through a single-pass extrusion process. Using a twin-screw extruder, chitosan plasticization was achieved in the presence of an acetic acid solution and glycerol, and directly mixed with metallocene polyethylene, mPE, to produce a masterbatch. Different dilutions of the masterbatch (2, 5 and 10 wt% of plasticized chitosan), in the presence of ethylene vinyl acetate, EVA, were subsequently achieved in single screw film extrusion. Very small plasticized chitosan domains (number average diameter <5 μm) were visible in the polymeric matrix. The resulting films presented a brown color and increasing haze with chitosan plasticized content. Mechanical properties of the mPE films were affected by the presence of plasticized chitosan, but improvement was observed as a result of some compatibility between mPE and chitosan in the presence of EVA. Finally the incorporation of plasticized chitosan affected mPE water vapor permeability while oxygen permeability remained constant. Copyright © 2014 Elsevier Ltd. All rights reserved.

Rotor internal friction instability

NASA Technical Reports Server (NTRS)

Bently, D. E.; Muszynska, A.

1985-01-01

Two aspects of internal friction affecting stability of rotating machines are discussed. The first role of internal friction consists of decreasing the level of effective damping during rotor subsynchronous and backward precessional vibrations caused by some other instability mechanisms. The second role of internal frication consists of creating rotor instability, i.e., causing self-excited subsynchronous vibrations. Experimental test results document both of these aspects.

Adaptive control reduces trip-induced forward gait instability among young adults.

PubMed

Wang, Ting-Yun; Bhatt, Tanvi; Yang, Feng; Pai, Yi-Chung

2012-04-30

A vital functional plasticity of humans is their ability to adapt to threats to posture stability. The purpose of this study was to investigate adaptation to repeated trips in walking. Sixteen young adults were recruited and exposed to the sudden (electronic-mechanical) release of an obstacle, 11-cm in height, in the path of over ground walking during the mid-to-late left swing phase. Although none of the subjects fell on the first of eight unannounced, consecutive trips, all of them had to rely on compensatory step with a step length significantly longer than their regular to reduce their instability. In the subsequent trials, they were able to rapidly make adaptive adjustments in the control of their center-of-mass (COM) stability both proactively and reactively (i.e., before and after hitting or crossing the obstacle), such that the need for taking compensatory step was substantially diminished. The proactive adaptations included a reduced forward COM velocity that lessened forward instability in mid-to-late stance and an elevated toe clearance that reduced the likelihood of obstacle contact. The reactive adjustments were characterized by improved trunk control (by reducing its forward rotation) and limb support (by increasing hip height), and reduced forward instability (by both the posterior COM shift and the reduction in its forward velocity). These findings suggest that young adults can adapt appropriately to repeated trip perturbations and to reduce trip-induced excessive instability in both proactive and reactive manners. Copyright © 2012 Elsevier Ltd. All rights reserved.

A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.

PubMed

McIntyre, Rebecca E; Nicod, Jérôme; Robles-Espinoza, Carla Daniela; Maciejowski, John; Cai, Na; Hill, Jennifer; Verstraten, Ruth; Iyer, Vivek; Rust, Alistair G; Balmus, Gabriel; Mott, Richard; Flint, Jonathan; Adams, David J

2016-08-09

In mammals the regulation of genomic instability plays a key role in tumor suppression and also controls genome plasticity, which is important for recombination during the processes of immunity and meiosis. Most studies to identify regulators of genomic instability have been performed in cells in culture or in systems that report on gross rearrangements of the genome, yet subtle differences in the level of genomic instability can contribute to whole organism phenotypes such as tumor predisposition. Here we performed a genome-wide association study in a population of 1379 outbred Crl:CFW(SW)-US_P08 mice to dissect the genetic landscape of micronucleus formation, a biomarker of chromosomal breaks, whole chromosome loss, and extranuclear DNA. Variation in micronucleus levels is a complex trait with a genome-wide heritability of 53.1%. We identify seven loci influencing micronucleus formation (false discovery rate <5%), and define candidate genes at each locus. Intriguingly at several loci we find evidence for sexual dimorphism in micronucleus formation, with a locus on chromosome 11 being specific to males. Copyright © 2016 McIntyre et al.

The effects of control field detuning on the modulation instability in a three-level quantum well system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borgohain, Nitu, E-mail: nituborgohain.ism@gmail.com; Konar, S.

The paper presents a theoretical study of the modulation instability of a continuous or quasi-continuous optical probe in a three level quantum well system under electromagnetically induced transparency. The modulation instability is affected by the control field detuning, as well as even-order dispersion and by the strength of Kerr (third-order) and quintic (fifth-order) nonlinearities. The fourth-order dispersion reduces the bandwidth over which modulation instability occurs, whereas the quintic nonlinearity saturates the growth of the modulation instability. Detuning the control field from resonance can significantly reduce the growth of the modulation instability at both low and high power levels. At lowmore » powers, the system becomes stable against modulation instability for small detuning of the control field and at high powers modulation instability disappears for larger detuning.« less

Modeling the hydro-mechanical responses of strip and circular punch loadings on water-saturated collapsible geomaterials

DOE PAGES

Sun, WaiChing; Chen, Qiushi; Ostien, Jakob T.

2013-11-22

A stabilized enhanced strain finite element procedure for poromechanics is fully integrated with an elasto-plastic cap model to simulate the hydro-mechanical interactions of fluid-infiltrating porous rocks with associative and non-associative plastic flow. We present a quantitative analysis on how macroscopic plastic volumetric response caused by pore collapse and grain rearrangement affects the seepage of pore fluid, and vice versa. Results of finite element simulations imply that the dissipation of excess pore pressure may significantly affect the stress path and thus alter the volumetric plastic responses.

Viscous shear heating instabilities in a 1-D viscoelastic shear zone

NASA Astrophysics Data System (ADS)

Homburg, J. M.; Coon, E. T.; Spiegelman, M.; Kelemen, P. B.; Hirth, G.

2010-12-01

Viscous shear instabilities may provide a possible mechanism for some intermediate depth earthquakes where high confining pressure makes it difficult to achieve frictional failure. While many studies have explored the feedback between temperature-dependent strain rate and strain-rate dependent shear heating (e.g. Braeck and Podladchikov, 2007), most have used thermal anomalies to initiate a shear instability or have imposed a low viscosity region in their model domain (John et al., 2009). By contrast, Kelemen and Hirth (2007) relied on an initial grain size contrast between a predetermined fine-grained shear zone and coarse grained host rock to initiate an instability. This choice is supported by observations of numerous fine grained ductile shear zones in shallow mantle massifs as well as the possibility that annealed fine grained fault gouge, formed at oceanic transforms, subduction related thrusts and ‘outer rise’ faults, could be carried below the brittle/ductile transition by subduction. Improving upon the work of Kelemen and Hirth (2007), we have developed a 1-D numerical model that describes the behavior of a Maxwell viscoelastic body with the rheology of dry olivine being driven at a constant velocity at its boundary. We include diffusion and dislocation creep, dislocation accommodated grain boundary sliding, and low-temperature plasticity (Peierls mechanism). Initial results suggest that including low-temperature plasticity inhibits the ability of the system to undergo an instability, similar to the results of Kameyama et al. (1999). This is due to increased deformation in the background allowing more shear heating to take place, and thus softening the system prior to reaching the peak stress. However if the applied strain rate is high enough (e.g. greater than 0.5 x 10-11 s-1 for a domain size of 2 km, an 8 m wide shear zone, a background grain size of 1 mm, a shear zone grain size of 150 μm, and an initial temperature of 650°C) dramatic instabilities can occur. The instability is enhanced by the development of a self-localizing thermal perturbation in the fine grained zone that is narrower than the original width of the fine-grained zone. To examine the effect of melting, we include a parameterization of partially molten rock viscosity as a function of temperature assuming a simple relationship between melt fraction and temperature. At T > ~1400°C, all other deformation mechanisms are deactivated but shear heating continues, allowing for continued temperature evolution. In addition a strain rate cap proportional to the shear wave velocity in olivine has been imposed, reflecting the maximum rate that changes in stress can be communicated through the system. While Kelemen and Hirth (2007) allowed for grain size evolution, this has not yet been implemented in our model. Adding grain size evolution as an additional strain softening mechanism would probably allow instabilities to develop at more geologically reasonable applied strain rates. In addition to discussing the stability of the olivine only system, we will explore grain size evolution during system evolution and evaluate the consequences that the grain size evolution and lithology have on the stability of the system.

The effect of spin induced magnetization on Jeans instability of viscous and resistive quantum plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Prerana, E-mail: preranaiitd@rediffmail.com; Chhajlani, R. K.

2014-03-15

The effect of spin induced magnetization and electrical resistivity incorporating the viscosity of the medium is examined on the Jeans instability of quantum magnetoplasma. Formulation of the system is done by using the quantum magnetohydrodynamic model. The analysis of the problem is carried out by normal mode analysis theory. The general dispersion relation is derived from set of perturbed equations to analyse the growth rate and condition of self-gravitational Jeans instability. To discuss the influence of resistivity, magnetization, and viscosity parameters on Jeans instability, the general dispersion relation is reduced for both transverse and longitudinal mode of propagations. In themore » case of transverse propagation, the gravitating mode is found to be affected by the viscosity, magnetization, resistivity, and magnetic field strength whereas Jeans criterion of instability is modified by the magnetization and quantum parameter. In the longitudinal mode of propagation, the gravitating mode is found to be modified due to the viscosity and quantum correction in which the Jeans condition of instability is influenced only by quantum parameter. The other non-gravitating Alfven mode in this direction is affected by finite electrical resistivity, spin induced magnetization, and viscosity. The numerical study for the growth rate of Jeans instability is carried out for both in the transverse and longitudinal direction of propagation to the magnetic field. The effect of various parameters on the growth rate of Jeans instability in quantum plasma is analysed.« less

Maternal Psychological Control, Maternal Borderline Personality Disorder, and Adolescent Borderline Features.

PubMed

Mahan, Rebecca M; Kors, Stephanie B; Simmons, Meredith L; Macfie, Jenny

2017-12-14

Linehan (1993) theorized that the experience of invalidating parenting interacts with emotional vulnerability in the development of borderline personality disorder (BPD). Parental psychological control is a type of invalidating parenting, defined as manipulation by parents of their offspring's psychological and emotional expression and experience (Barber, 1996). In a normative sample of adolescent females, adolescent-reported maternal psychological control was related to maternal borderline symptoms (Zalewski et al., 2014). The current study expanded on these findings to sample mothers with a diagnosis of BPD (n = 28) and normative comparisons (n = 28) with male and female adolescents aged 14-18. We assessed maternal and adolescent self-reported borderline features (affective instability, negative relationships, identity disturbance, and self-harm) and coded maternal psychological control from filmed problem-solving interactions. Controlling for current major depressive disorder and family income, mothers with BPD used more total psychological control with their adolescents in comparison with normative mothers. Further, maternal psychological control was positively associated with all mothers' borderline features and with adolescent affective instability. Finally, we found a significant indirect effect for maternal affective instability between maternal total psychological control and adolescent affective instability. We discuss adolescents' risk of developing BPD themselves and prevention and treatment implications. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Neuronal cytoskeleton in synaptic plasticity and regeneration.

PubMed

Gordon-Weeks, Phillip R; Fournier, Alyson E

2014-04-01

During development, dynamic changes in the axonal growth cone and dendrite are necessary for exploratory movements underlying initial axo-dendritic contact and ultimately the formation of a functional synapse. In the adult central nervous system, an impressive degree of plasticity is retained through morphological and molecular rearrangements in the pre- and post-synaptic compartments that underlie the strengthening or weakening of synaptic pathways. Plasticity is regulated by the interplay of permissive and inhibitory extracellular cues, which signal through receptors at the synapse to regulate the closure of critical periods of developmental plasticity as well as by acute changes in plasticity in response to experience and activity in the adult. The molecular underpinnings of synaptic plasticity are actively studied and it is clear that the cytoskeleton is a key substrate for many cues that affect plasticity. Many of the cues that restrict synaptic plasticity exhibit residual activity in the injured adult CNS and restrict regenerative growth by targeting the cytoskeleton. Here, we review some of the latest insights into how cytoskeletal remodeling affects neuronal plasticity and discuss how the cytoskeleton is being targeted in an effort to promote plasticity and repair following traumatic injury in the central nervous system. © 2013 International Society for Neurochemistry.

40 CFR 62.14102 - Affected facilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... plastics/rubber recycling unit (as defined in 40 CFR 60.51b) are not subject to this subpart if the owner or operator of the plastics/rubber recycling unit keeps records of the weight of plastics, rubber... chemical plants or petroleum refineries that use feestocks produced by plastics/rubber recycling units are...

40 CFR 62.14102 - Affected facilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... plastics/rubber recycling unit (as defined in 40 CFR 60.51b) are not subject to this subpart if the owner or operator of the plastics/rubber recycling unit keeps records of the weight of plastics, rubber... chemical plants or petroleum refineries that use feestocks produced by plastics/rubber recycling units are...

40 CFR 62.14102 - Affected facilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... plastics/rubber recycling unit (as defined in 40 CFR 60.51b) are not subject to this subpart if the owner or operator of the plastics/rubber recycling unit keeps records of the weight of plastics, rubber... chemical plants or petroleum refineries that use feestocks produced by plastics/rubber recycling units are...

40 CFR 62.14102 - Affected facilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... plastics/rubber recycling unit (as defined in 40 CFR 60.51b) are not subject to this subpart if the owner or operator of the plastics/rubber recycling unit keeps records of the weight of plastics, rubber... chemical plants or petroleum refineries that use feestocks produced by plastics/rubber recycling units are...

40 CFR 62.14102 - Affected facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... plastics/rubber recycling unit (as defined in 40 CFR 60.51b) are not subject to this subpart if the owner or operator of the plastics/rubber recycling unit keeps records of the weight of plastics, rubber... chemical plants or petroleum refineries that use feestocks produced by plastics/rubber recycling units are...

Embrittlement and Flow Localization in Reactor Structural Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xianglin Wu; Xiao Pan; James Stubbins

2006-10-06

Many reactor components and structural members are made from metal alloys due, in large part, to their strength and ability to resist brittle fracture by plastic deformation. However, brittle fracture can occur when structural material cannot undergo extensive, or even limited, plastic deformation due to irradiation exposure. Certain irradiation conditions lead to the development of a damage microstructure where plastic flow is limited to very small volumes or regions of material, as opposed to the general plastic flow in unexposed materials. This process is referred to as flow localization or plastic instability. The true stress at the onset of neckingmore » is a constant regardless of the irradiation level. It is called 'critical stress' and this critical stress has strong temperature dependence. Interrupted tensile testes of 316L SS have been performed to investigate the microstructure evolution and competing mechanism between mechanic twinning and planar slip which are believed to be the controlling mechanism for flow localization. Deformation twinning is the major contribution of strain hardening and good ductility for low temperatures, and the activation of twinning system is determined by the critical twinning stress. Phases transform and texture analyses are also discussed in this study. Finite element analysis is carried out to complement the microstructural analysis and for the prediction of materaials performance with and without stress concentration and irradiation.« less

Richtmyer-Meshkov jet formation from rear target ripples in plastic and plastic/aluminum laser targets

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Velikovich, A. L.; Karasik, M.; Serlin, V.; Weaver, J. L.; Schmitt, A. J.; Obenschain, S. P.

2015-11-01

We report experimental observations of jets produced from the rear surface of laser targets after a passage of the laser-driven shock wave. As in our previous work, Aglitskiy et al., Phys. Plasmas (2012), the jets are produced via the shaped-charge mechanism, a manifestation of a Richtmyer-Meshkov instability for a particular case of the Atwood number A =-1. The experiments done on the KrF Nike laser facility with laser wavelength 248 nm, a 4 ns pulse, and low-energy drive regime that used only 1 to 3 overlapping Nike beams and generated ablative pressure below 1 Mbar. Our 50 um thick planar targets were rippled on the rear side with wavelength 45 μm and peak-to-valley amplitude 15 μm. The targets were made either of solid plastic or of aluminum with a 10 μm thick plastic ablator attached to avoid the radiation preheat. The jets were extremely well collimated, which made possible our side-on observations with monochromatic x-ray imaging. We saw a regular set of jets, clearly separated along the 500 μm line of sight. Aluminum jets were found to be slightly better collimated than plastic jets. A quasi-spherical late-time expansion of Al jets starting from the tips has not been previously seen in experiments or simulations. Work supported by the US DOE/NNSA.

Increased plastic litter cover affects the foraging activity of the sandy intertidal gastropod Nassarius pullus.

PubMed

Aloy, Alexander B; Vallejo, Benjamin M; Juinio-Meñez, Marie Antonette

2011-08-01

This study analyzed the foraging behavior of the gastropod Nassarius pullus on garbage-impacted sandy shores of Talim Bay, Batangas, Philippines. The effect of different levels of plastic garbage cover on foraging efficiency was investigated. Controlled in situ baiting experiments were conducted to quantify aspects of foraging behavior as affected by the levels of plastic litter cover in the foraging area. The results of the study indicated that the gastropod's efficiency in locating and in moving towards a food item generally decreased as the level of plastic cover increased. Prolonged food searching time and increased self-burial in sand were highly correlated with increased plastic cover. The accuracy of orientation towards the actual position of the bait decreased significantly when the amount of plastic cover increased to 50%. These results are consistent with the significant decreases in the abundance of the gastropod observed during periods of deposition of large amounts of plastic and other debris on the shore. Copyright © 2011 Elsevier Ltd. All rights reserved.

The Analysis of Crack Growth Initiation, Propagation, and Arrest in Flawed Ship Structures Subjected to Dynamic Loading

DTIC Science & Technology

1984-08-10

most current efforts in EPFM are focused on the application of the J-resistance curve to predict crack initiation and fracture instability. However...element code FRACDYN, which has since been used to solve a variety of problems related to the Navy, NRC, and several industrial applications . Of...that this parameter remains constant during elastic-plastic stable crack growth--see Reference (9). This fact, together with its ease of application

Nonlinear Waves in Rods

DTIC Science & Technology

1981-05-01

0 and P > 0 everywhere. This also implies from (17) that Www 1Wuu - Wu w1 > 0 so that necking instabilities have been ruled out (see Antman [12], pp... Antman , "Qualitative Theory of the Ordinary Differential Equa- tions of Nonlinear Elasticity," in Mechanics Today, V. 1, ed. S. Nemat- Nasser...the Propagation of Plastic Strain in a Cylindrical Rod," J. Mech. Phys. Sol., 13, 1965, pp. 55-68. 7. S. S. Antman , The Theory of Rods, Handbuch der

Similarities in temperature-dependent gene expression plasticity across timescales in threespine stickleback (Gasterosteus aculeatus).

PubMed

Metzger, David C H; Schulte, Patricia M

2018-04-14

Phenotypic plasticity occurs at a variety of timescales, but little is known about the degree to which plastic responses at different timescales are associated with similar underlying molecular processes, which is critical for assessing the effects of plasticity on evolutionary trajectories. To address this issue, we identified differential gene expression in response to developmental temperature in the muscle transcriptome of adult threespine stickleback (Gasterosteus aculeatus) exposed to 12, 18 and 24°C until hatch and then held at 18°C for 9 months and compared these results to differential gene expression in response to adult thermal acclimation in stickleback developed at 18°C and then acclimated to 5 and 25°C as adults. Adult thermal acclimation affected the expression of 7,940 and 7,015 genes in response to cold and warm acclimation, respectively, and 4,851 of these genes responded in both treatments. In contrast, the expression of only 33 and 29 genes was affected by cold and warm development, respectively. The majority of the genes affected by developmental temperature were also affected by adult acclimation temperature. Many genes that were differentially expressed as a result of adult acclimation were associated with previously identified temperature-dependent effects on DNA methylation patterns, suggesting a role of epigenetic mechanisms in regulating gene expression plasticity during acclimation. Taken together, these results demonstrate similarities between the persistent effects of developmental plasticity on gene expression and the effects of adult thermal acclimation, emphasizing the potential for mechanistic links between plasticity acting at these different life stages. © 2018 John Wiley & Sons Ltd.

Seabirds and marine plastic debris in the northeastern Atlantic: A synthesis and recommendations for monitoring and research.

PubMed

O'Hanlon, Nina J; James, Neil A; Masden, Elizabeth A; Bond, Alexander L

2017-12-01

Marine plastic pollution is an increasing, and global, environmental issue. Numerous marine species are affected by plastic debris through entanglement, nest incorporation, and ingestion, which can lead to lethal and sub-lethal impacts. However, in the northeastern Atlantic Ocean, an area of international importance for seabirds, there has been little effort to date to assess information from studies of wildlife and plastic to better understand the spatiotemporal variation of how marine plastic affects different seabird species. To improve our understanding of seabirds and marine plastic in this region, we completed a synthesis of the published and grey literature to obtain information on all known documented cases of plastic ingestion and nest incorporation by this group. We found that of 69 seabird species that commonly occur in the northeastern Atlantic, 25 had evidence of ingesting plastic. However, data on plastic ingestion was available for only 49% of all species, with 74% of investigated species recorded ingesting plastic. We found only three published studies on nest incorporation, for the Northern Gannet (Morus bassanus) and Black-legged Kittiwake (Rissa tridactyla). For many species, sample sizes were small or not reported, and only 39% of studies were from the 21st century, whilst information from multiple countries and years was only available for 11 species. This indicates that we actually know very little about the current prevalence of plastic ingestion and nest incorporation for many species, several of them globally threatened. Furthermore, in the majority of studies, the metrics reported were inadequate to carry out robust comparisons among locations and species or perform meta-analyses. We recommend multi-jurisdictional collaboration to obtain a more comprehensive and current understanding of how marine plastic is affecting seabirds in the northeastern Atlantic Ocean. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Potential for the Vishniac instability in ionizing shock waves propagating into cold gases

NASA Astrophysics Data System (ADS)

Robinson, A. P. L.; Pasley, J.

2018-05-01

The Vishniac instability was posited as an instability that could affect supernova remnants in their late stage of evolution when subject to strong radiative cooling, which can drive the effective ratio of specific heats below 1.3. The potential importance of this instability to these astrophysical objects has motivated a number of laser-driven laboratory studies. However, the Vishniac instability is essentially a dynamical instability that should operate independently of whatever physical processes happen to reduce the ratio of specific heats. In this paper, we examine the possibility that ionization and molecular dissociation processes can achieve this, and we show that this is possible for a certain range of shock wave Mach numbers for ionizing/dissociating shock waves propagating into cold atomic and molecular gases.

Compaction-Based Deformable Terrain Model as an Interface for Real-Time Vehicle Dynamics Simulations

DTIC Science & Technology

2013-04-16

to vehicular loads, and the resulting visco-elastic-plastic stress/strain on the affected soil volume. Pedo transfer functions allow for the...resulting visco-elastic-plastic stress/strain on the affected soil volume. Pedo transfer functions allow for the calculation of the soil mechanics model

Athermal brittle-to-ductile transition in amorphous solids.

PubMed

Dauchot, Olivier; Karmakar, Smarajit; Procaccia, Itamar; Zylberg, Jacques

2011-10-01

Brittle materials exhibit sharp dynamical fractures when meeting Griffith's criterion, whereas ductile materials blunt a sharp crack by plastic responses. Upon continuous pulling, ductile materials exhibit a necking instability that is dominated by a plastic flow. Usually one discusses the brittle to ductile transition as a function of increasing temperature. We introduce an athermal brittle to ductile transition as a function of the cutoff length of the interparticle potential. On the basis of extensive numerical simulations of the response to pulling the material boundaries at a constant speed we offer an explanation of the onset of ductility via the increase in the density of plastic modes as a function of the potential cutoff length. Finally we can resolve an old riddle: In experiments brittle materials can be strained under grip boundary conditions and exhibit a dynamic crack when cut with a sufficiently long initial slot. Mysteriously, in molecular dynamics simulations it appeared that cracks refused to propagate dynamically under grip boundary conditions, and continuous pulling was necessary to achieve fracture. We argue that this mystery is removed when one understands the distinction between brittle and ductile athermal amorphous materials.

Deformation behaviour of Rheocast A356 Al alloy at microlevel considering approximated RVEs

NASA Astrophysics Data System (ADS)

Islam, Sk. Tanbir; Das, Prosenjit; Das, Santanu

2015-03-01

A micromechanical approach is considered here to predict the deformation behaviour of Rheocast A356 (Al-Si-Mg) alloy. Two representative volume elements (RVEs) are modelled in the finite element (FE) framework. Two dimensional approximated microstructures are generated assuming elliptic grains, based on the grain size, shape factor and area fraction of the primary Al phase of the said alloy at different processing condition. Plastic instability is shown using stress and strain distribution between the Al rich primary and Si rich eutectic phases under different boundary conditions. Boundary conditions are applied on the approximated RVEs in such a manner, so that they represent the real life situation depending on their position on a cylindrical tensile test sample. FE analysis is carried out using commercial finite element code ABAQUS without specifying any damage or failure criteria. Micro-level in-homogeneity leads to incompatible deformation between the constituent phases of the rheocast alloy and steers plastic strain localisation. Plastic stain localised regions within the RVEs are predicted as the favourable sites for void nucleation. Subsequent growth of nucleated voids leads to final failure of the materials under investigation.

Shock-induced perturbation evolution in planar laser targets

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Karasik, M.; Velikovich, A. L.; Serlin, V.; Weaver, J. L.; Kessler, T. J.; Schmitt, A. J.; Obenschain, S. P.; Metzler, N.; Oh, J.

2013-10-01

Experimental studies of hydrodynamic perturbation evolution triggered by a laser-driven shock wave in a planar target done on the KrF Nike laser facility are reported. The targets were made of solid plastic and/or plastic foam with single mode sinusoidal perturbation on the front or back surface or plastic/foam interface. Two specific cases are discussed. When a planar solid plastic target rippled at the front side is irradiated with a 350 ps long laser pulse, ablative Richtmyer-Meshkov (RM) oscillation of its areal mass modulation amplitude is detected while the laser is on, followed by observed strong oscillations of the areal mass in the unsupported shock flow after the laser pulse ends. When the target is rippled at the rear side, the nature of the perturbation evolution after the shock breakout is determined by the strength of the laser-driven shock wave. At pressure below 1 Mbar shock interaction with rear-surface ripples produces planar collimated jets manifesting the development of a classical RM instability in a weakly compressible shocked fluid. At shock pressure ~ 8 Mbar sufficient for vaporizing the shocked target material we observed instead the strong areal mass oscillations characteristic of a rippled centered rarefaction wave. Work supported by US DOE, Defense Programs.

Reproducing Kernel Particle Method in Plasticity of Pressure-Sensitive Material with Reference to Powder Forming Process

NASA Astrophysics Data System (ADS)

Khoei, A. R.; Samimi, M.; Azami, A. R.

2007-02-01

In this paper, an application of the reproducing kernel particle method (RKPM) is presented in plasticity behavior of pressure-sensitive material. The RKPM technique is implemented in large deformation analysis of powder compaction process. The RKPM shape function and its derivatives are constructed by imposing the consistency conditions. The essential boundary conditions are enforced by the use of the penalty approach. The support of the RKPM shape function covers the same set of particles during powder compaction, hence no instability is encountered in the large deformation computation. A double-surface plasticity model is developed in numerical simulation of pressure-sensitive material. The plasticity model includes a failure surface and an elliptical cap, which closes the open space between the failure surface and hydrostatic axis. The moving cap expands in the stress space according to a specified hardening rule. The cap model is presented within the framework of large deformation RKPM analysis in order to predict the non-uniform relative density distribution during powder die pressing. Numerical computations are performed to demonstrate the applicability of the algorithm in modeling of powder forming processes and the results are compared to those obtained from finite element simulation to demonstrate the accuracy of the proposed model.

Suppression of stimulated Brillouin instability of a beat-wave of two lasers in multiple-ion-species plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yadav, Pinki; Gupta, D. N., E-mail: dngupta@physics.du.ac.in; Avinash, K.

2016-01-15

Stimulated Brillouin instability of a beat-wave of two lasers in plasmas with multiple-ion-species (negative-ions) was studied. The inclusion of negative-ions affects the growth of ion-acoustic wave in Brillouin scattering. Thus, the growth rate of instability is suppressed significantly by the density of negative-ions. To obey the phase-matching condition, the growth rate of the instability attains a maxima for an appropriate scattering angle (angle between the pump and scattered sideband waves). This study would be technologically important to have diagnostics in low-temperature plasmas.

Effects of energetic particle phase space modifications by instabilities on integrated modeling

NASA Astrophysics Data System (ADS)

Podestà, M.; Gorelenkova, M.; Fredrickson, E. D.; Gorelenkov, N. N.; White, R. B.

2016-11-01

Tokamak plasmas can feature a large population of energetic particles (EP) from neutral beam injection or fusion reactions. In turn, energetic particles can drive instabilities, which affect the driving EP population leading to a distortion of the original EP distribution function and of quantities that depend on it. The latter include, for example, neutral beam (NB) current drive and plasma heating through EP thermalization. Those effects must be taken into account to enable reliable and quantitative simulations of discharges for present devices as well as predictions for future burning plasmas. Reduced models for EP transport are emerging as an effective tool for long time-scale integrated simulations of tokamak plasmas, possibly including the effects of instabilities on EP dynamics. Available models differ in how EP distribution properties are modified by instabilities, e.g. in terms of gradients in real or phase space. It is therefore crucial to assess to what extent different assumptions in the transport models affect predicted quantities such as EP profile, energy distribution, NB driven current and energy/momentum transfer to the thermal populations. A newly developed kick model, which includes modifications of the EP distribution by instabilities in both real and velocity space, is used in this work to investigate these issues. Coupled to TRANSP simulations, the kick model is used to analyze NB-heated NSTX and DIII-D discharges featuring unstable Alfvén eigenmodes (AEs). Results show that instabilities can strongly affect the EP distribution function, and modifications propagate to macroscopic quantities such as NB-driven current profile and NB power transferred to the thermal plasma species. Those important aspects are only qualitatively captured by simpler fast ion transport models that are based on radial diffusion of energetic ions only.

Effects of energetic particle phase space modifications by instabilities on integrated modeling

DOE PAGES

Podesta, M.; Gorelenkova, M.; Fredrickson, E. D.; ...

2016-07-22

Tokamak plasmas can feature a large population of energetic particles (EP) from neutral beam injection or fusion reactions. In turn, energetic particles can drive instabilities, which affect the driving EP population leading to a distortion of the original EP distribution function and of quantities that depend on it. The latter include, for example, neutral beam (NB) current drive and plasma heating through EP thermalization. Those effects must be taken into account to enable reliable and quantitative simulations of discharges for present devices as well as predictions for future burning plasmas. Reduced models for EP transport are emerging as an effectivemore » tool for long time-scale integrated simulations of tokamak plasmas, possibly including the effects of instabilities on EP dynamics. Available models differ in how EP distribution properties are modified by instabilities, e.g. in terms of gradients in real or phase space. It is therefore crucial to assess to what extent different assumptions in the transport models affect predicted quantities such as EP profile, energy distribution, NB driven current and energy/momentum transfer to the thermal populations. A newly developed kick model, which includes modifications of the EP distribution by instabilities in both real and velocity space, is used in this work to investigate these issues. Coupled to TRANSP simulations, the kick model is used to analyze NB-heated NSTX and DIII-D discharges featuring unstable Alfvén eigenmodes (AEs). Results show that instabilities can strongly affect the EP distribution function, and modifications propagate to macroscopic quantities such as NB-driven current profile and NB power transferred to the thermal plasma species. Furthermore, those important aspects are only qualitatively captured by simpler fast ion transport models that are based on radial diffusion of energetic ions only.« less

The Zombie Instability: Using Numerical Simulation to Design a Laboratory Experiment

NASA Astrophysics Data System (ADS)

Wang, Meng; Pei, Suyang; Jiang, Chung-Hsiang; Hassanzadeh, Pedram; Marcus, Philip

2014-11-01

A new type of finite amplitude-instability has been found in numerical simulations of stratified, rotating, shear flows. The instability occurs via baroclinic critical layers that create linearly unstable vortex layers, which roll-up into vortices. Under the right conditions, those vortices can form a new generation of vortices, resulting in ``vortex self-replication'' that fills the fluid with vortices. Creating this instability in a laboratory would provide further evidence for the existence of the instability, which we first found in numerical simulations of protoplanetary disks. To design a laboratory experiment we need to know how the flow parameters-- shear, rotation and stratification, etc. affect the instability. To build an experiment economically, we also need to know how the finite-amplitude trigger of the instability scales with viscosity and the size of the domain. In this talk, we summarize our findings. We present a map, in terms of the experimentally controllable parameters, that shows where the instability occurs and whether the instability creates a few isolated transient vortices, a few long-lived vortices, or long-lived, self-replicating vortices that fill the entire flow.

Beauty and the beast: management of breast cancer after plastic surgery.

PubMed

Bleicher, Richard J; Topham, Neal S; Morrow, Monica

2008-04-01

Cosmetic surgery procedures increase in incidence annually, with 11 million performed in 2006. Because breast cancer is the most frequently occurring malignancy in women, a personal history of cosmetic surgery in those undergoing treatment for breast cancer is becoming more common. This review identified key studies from the PubMed database, to consolidate existing data related to treatment of breast cancer after plastic surgery. Data were reviewed for factors affecting breast cancer treatment after breast augmentation, breast reduction, abdominoplasty, and suction lipectomy. There are little comprehensive data on the management of breast cancer after plastic surgical procedures. Plastic surgery may affect diagnostic imaging, surgical options, and radiotherapy management. Breast augmentation and reduction are two of the most common cosmetic procedures performed and knowledge of their influence on the incidence, diagnosis, and treatment of breast cancer is important for proper management. Plastic surgery does not significantly affect breast cancer outcomes but does present management challenges that must be anticipated when deciding various treatment options. Knowledge of the existing literature may be helpful in discussing those options with patients and planning the multidisciplinary approach to this malignancy.

Mood instability is a common feature of mental health disorders and is associated with poor clinical outcomes

PubMed Central

Lloyd, Theodore; Jackson, Richard; Ball, Michael; Shetty, Hitesh; Broadbent, Matthew; Geddes, John R; Stewart, Robert; McGuire, Philip; Taylor, Matthew

2015-01-01

Objectives Mood instability is a clinically important phenomenon but has received relatively little research attention. The objective of this study was to assess the impact of mood instability on clinical outcomes in a large sample of people receiving secondary mental healthcare. Design Observational study using an anonymised electronic health record case register. Setting South London and Maudsley NHS Trust (SLaM), a large provider of inpatient and community mental healthcare in the UK. Participants 27 704 adults presenting to SLaM between April 2006 and March 2013 with a psychotic, affective or personality disorder. Exposure The presence of mood instability within 1 month of presentation, identified using natural language processing (NLP). Main outcome measures The number of days spent in hospital, frequency of hospital admission, compulsory hospital admission and prescription of antipsychotics or non-antipsychotic mood stabilisers over a 5-year follow-up period. Results Mood instability was documented in 12.1% of people presenting to mental healthcare services. It was most frequently documented in people with bipolar disorder (22.6%), but was common in people with personality disorder (17.8%) and schizophrenia (15.5%). It was associated with a greater number of days spent in hospital (β coefficient 18.5, 95% CI 12.1 to 24.8), greater frequency of hospitalisation (incidence rate ratio 1.95, 1.75 to 2.17), greater likelihood of compulsory admission (OR 2.73, 2.34 to 3.19) and an increased likelihood of prescription of antipsychotics (2.03, 1.75 to 2.35) or non-antipsychotic mood stabilisers (2.07, 1.77 to 2.41). Conclusions Mood instability occurs in a wide range of mental disorders and is not limited to affective disorders. It is generally associated with relatively poor clinical outcomes. These findings suggest that clinicians should screen for mood instability across all common mental health disorders. The data also suggest that targeted interventions for mood instability may be useful in patients who do not have a formal affective disorder. PMID:25998036

40 CFR 63.5790 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2010 CFR

2010-07-01

... CATEGORIES National Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites... subpart applies to each new or existing affected source at reinforced plastic composites production...) manufacturing, mixing, cleaning of equipment used in reinforced plastic composites manufacture, HAP-containing...

A 2-DOF microstructure-dependent model for the coupled torsion/bending instability of rotational nanoscanner

NASA Astrophysics Data System (ADS)

Keivani, M.; Abadian, N.; Koochi, A.; Mokhtari, J.; Abadyan, M.

2016-10-01

It has been well established that the physical performance of nanodevices might be affected by the microstructure. Herein, a two-degree-of-freedom model base on the modified couple stress theory is developed to incorporate the impact of microstructure in the torsion/bending coupled instability of rotational nanoscanner. Effect of microstructure dependency on the instability parameters is determined as a function of the microstructure parameter, bending/torsion coupling ratio, van der Waals force parameter and geometrical dimensions. It is found that the bending/torsion coupling substantially affects the stable behavior of the scanners especially those with long rotational beam elements. Impact of microstructure on instability voltage of the nanoscanner depends on coupling ratio and the conquering bending mode over torsion mode. This effect is more highlighted for higher values of coupling ratio. Depending on the geometry and material characteristics, the presented model is able to simulate both hardening behavior (due to microstructure) and softening behavior (due to torsion/bending coupling) of the nanoscanners.

A Comparison of the Fatigue Performance of Woven and Non-Woven CFRP (carbon Fibre Reinforced Plastics)

DTIC Science & Technology

1985-06-01

certain polymer fibres may defibrillate through exposure to fatigae loading and 20severe environments and subsequently also fail by fibre...fibre by weight than two non-woven plies.- The laminates were stored in a controlled environment at 230C and 652 relative humidity for at least 3 months...instability triggered by the defibrillation . tn fatisue the resin and the fibre/matrix interface become damaged ind are len able to support the fibres, thus

Young Plastic Surgeons Forum member survey: Part II. Advocacy in plastic surgery: opinions toward the ASPS and PlastyPAC.

PubMed

Ver Halen, Jon P; Chen, Andrew; Jeffers, Lynn; Basu, C Bob

2014-08-01

Given the continued evolution of the American health system, the authors explored young plastic surgeons' attitudes on challenges affecting the specialty and the future role of organized plastic surgery and its advocacy mission. A 21-question online survey was distributed to all members of the Young Plastic Surgeons Forum. Questions were related to demographics, attitudes toward policy issues, participation in the American Society of Plastic Surgeons, and its advocacy efforts. The survey was e-mailed to 2155 Forum members, of which 397 responded (19% response rate). Young plastic surgeons appear to be interested in American Society of Plastic Surgeons and PlastyPAC, as evidenced by a higher than normal response rate to this survey and rate of contribution. However, a lack of awareness about the details of the organizations and mechanisms for involvement remains. Scope-of-practice issues and encroachment on the specialty by noncore providers remain the top concern of young plastic surgeons. Other top concerns were financial barriers to participation in advocacy efforts and concerns with return on investment on PlastyPAC contributions. A majority received minimal or no public policy education on issues affecting plastic surgery during training. A minority currently participate in American Society of Plastic Surgeons advocacy efforts. These data represent the first such collection of opinions from Young Plastic Surgeons members regarding goals and directions of the American Society of Plastic Surgeons and PlastyPAC. These organizations are in a uniquely strong position to enlist participation from and provide for the future success of the profession's younger members.

Individual variation in behavioural plasticity: direct and indirect effects of boldness, exploration and sociability on habituation to predators in lizards.

PubMed

Rodríguez-Prieto, Iñaki; Martín, José; Fernández-Juricic, Esteban

2011-01-22

Little is known about the factors causing variation in behavioural plasticity and the interplay between personality and plasticity. Habituation to predators is a special case of behavioural plasticity. We investigated the direct and indirect effects of boldness, exploration and sociability traits on the habituation ability of Iberian wall lizards, considering exposure and sex effects. Individual boldness was consistent across several non-habituation contexts, but it did not significantly affect habituation. Exploration had a strong direct effect on habituation, with more exploratory individuals being able to habituate faster than less exploratory ones, probably because of their ability to assess risk better. Individual variation in habituation was also affected by sociability, but this was an indirect effect mediated by exposure to the predator. Less social individuals avoided refuges with conspecific cues, increasing exposure to the predator and eventually habituation. Finally, the direct effects of sex (females habituated faster than males) were opposite to its indirect effects through exposure. We conclude that risk assessment, instead of the proactivity-reactivity gradient usually considered in the literature, can affect behavioural plasticity through complex interactions between direct and indirect effects, including exploratory behaviour, degree of exposure to the predator and sex, which represent novel mechanisms generating inter-individual variation in plasticity.

Numerical modelling of hydrologically-driven slope instability by means of porous media mechanics

NASA Astrophysics Data System (ADS)

Kakogiannou, Evanthia; Sanavia, Lorenzo; Lora, Marco; Schrefler, Bernhard

2015-04-01

Heavy rainfall can trigger slope failure which generally involves shallow soil deposit of different grading and origin usually in a state of partial saturation. In this case of slope instability, the behaviour of the soil slope is closely related not only to the distribution of pore-water pressure but also to the stress state during rainfall infiltration involving both mechanical and hydrological processes. In order to understand better these physical key processes, in this research work, the modelling of rainfall induced slope failure is considered as a coupled variably saturated hydro-mechanical problem. Therefore, the geometrically linear finite element code Comes-Geo for non-isothermal elasto-plastic multiphase solid porous materials is used, as developed by B.A. Schrefler and his co-workers. In this context, a detailed numerical analysis of an experimental slope stability test due to rainfall infiltration is presented. The main goals of this work are to understand the triggering mechanisms during the progressive failure, the effect of using different constitutive models of the mechanical soil behavior on the numerical results and the use of the second order work criterion on the detection of slope instability.

Impact of porosity on Jeans instability in viscous quantum magnetoplasma

NASA Astrophysics Data System (ADS)

Prajapat, V.; Sutar, D. L.; Pensia, R. K.

2018-05-01

This paper treats the Jeans instability improved at the theoretical investigation of the presence of viscosity and resistivity in the porous medium. Following the normal mode analysis using the QMHD model, the dispersion relation is discussed for wave propagation in longitudinal and transverse direction. The Jeans criteria of instability are affected by the presence of porosity. The graphical presentation shows that porosity has a stabilizing effect while resistivity has destabilizing effect in the system.

Causes of genome instability: the effect of low dose chemical exposures in modern society

PubMed Central

Langie, Sabine A.S.; Koppen, Gudrun; Desaulniers, Daniel; Al-Mulla, Fahd; Al-Temaimi, Rabeah; Amedei, Amedeo; Azqueta, Amaya; Bisson, William H.; Brown, Dustin; Brunborg, Gunnar; Charles, Amelia K.; Chen, Tao; Colacci, Annamaria; Darroudi, Firouz; Forte, Stefano; Gonzalez, Laetitia; Hamid, Roslida A.; Knudsen, Lisbeth E.; Leyns, Luc; Lopez de Cerain Salsamendi, Adela; Memeo, Lorenzo; Mondello, Chiara; Mothersill, Carmel; Olsen, Ann-Karin; Pavanello, Sofia; Raju, Jayadev; Rojas, Emilio; Roy, Rabindra; Ryan, Elizabeth; Ostrosky-Wegman, Patricia; Salem, Hosni K.; Scovassi, Ivana; Singh, Neetu; Vaccari, Monica; Van Schooten, Frederik J.; Valverde, Mahara; Woodrick, Jordan; Zhang, Luoping; van Larebeke, Nik; Kirsch-Volders, Micheline; Collins, Andrew R.

2015-01-01

Genome instability is a prerequisite for the development of cancer. It occurs when genome maintenance systems fail to safeguard the genome’s integrity, whether as a consequence of inherited defects or induced via exposure to environmental agents (chemicals, biological agents and radiation). Thus, genome instability can be defined as an enhanced tendency for the genome to acquire mutations; ranging from changes to the nucleotide sequence to chromosomal gain, rearrangements or loss. This review raises the hypothesis that in addition to known human carcinogens, exposure to low dose of other chemicals present in our modern society could contribute to carcinogenesis by indirectly affecting genome stability. The selected chemicals with their mechanisms of action proposed to indirectly contribute to genome instability are: heavy metals (DNA repair, epigenetic modification, DNA damage signaling, telomere length), acrylamide (DNA repair, chromosome segregation), bisphenol A (epigenetic modification, DNA damage signaling, mitochondrial function, chromosome segregation), benomyl (chromosome segregation), quinones (epigenetic modification) and nano-sized particles (epigenetic pathways, mitochondrial function, chromosome segregation, telomere length). The purpose of this review is to describe the crucial aspects of genome instability, to outline the ways in which environmental chemicals can affect this cancer hallmark and to identify candidate chemicals for further study. The overall aim is to make scientists aware of the increasing need to unravel the underlying mechanisms via which chemicals at low doses can induce genome instability and thus promote carcinogenesis. PMID:26106144

Studying plastic shear localization in aluminum alloys under dynamic loading

NASA Astrophysics Data System (ADS)

Bilalov, D. A.; Sokovikov, M. A.; Chudinov, V. V.; Oborin, V. A.; Bayandin, Yu. V.; Terekhina, A. I.; Naimark, O. B.

2016-12-01

An experimental and theoretical study of plastic shear localization mechanisms observed under dynamic deformation using the shear-compression scheme on a Hopkinson-Kolsky bar has been carried out using specimens of AMg6 alloy. The mechanisms of plastic shear instability are associated with collective effects in the microshear ensemble in spatially localized areas. The lateral surface of the specimens was photographed in the real-time mode using a CEDIP Silver 450M high-speed infrared camera. The temperature distribution obtained at different times allowed us to trace the evolution of the localization of the plastic strain. Based on the equations that describe the effect of nonequilibrium transitions on the mechanisms of structural relaxation and plastic flow, numerical simulation of plastic shear localization has been performed. A numerical experiment relevant to the specimen-loading scheme was carried out using a system of constitutive equations that reflect the part of the structural relaxation mechanisms caused by the collective behavior of microshears with the autowave modes of the evolution of the localized plastic flow. Upon completion of the experiment, the specimens were subjected to microstructure analysis using a New View-5010 optical microscope-interferometer. After the dynamic deformation, the constancy of the Hurst exponent, which reflects the relationship between the behavior of defects and roughness induced by the defects on the surfaces of the specimens is observed in a wider range of spatial scales. These investigations revealed the distinctive features in the localization of the deformation followed by destruction to the script of the adiabatic shear. These features may be caused by the collective multiscale behavior of defects, which leads to a sharp decrease in the stress-relaxation time and, consequently, a localized plastic flow and generation of fracture nuclei in the form of adiabatic shear. Infrared scanning of the localization zone of the plastic strain in situ and the subsequent study of the defect structure corroborated the hypothesis about the decisive role of non-equilibrium transitions in defect ensembles during the evolution of a localized plastic flow.

Deep mechanisms of social affect - Plastic parental brain mechanisms for sensitivity versus contempt.

PubMed

Swain, James E; Ho, S Shaun

2017-01-01

Insensitive parental thoughts and affect, similar to contempt, may be mapped onto a network of basic emotions moderated by attitudinal representations of social-relational value. Brain mechanisms that reflect emotional valence of baby signals among parents vary according to individual differences and show plasticity over time. Furthermore, mental health problems and treatments for parents may affect these brain systems toward or away from contempt, respectively.

Lithosperic rheology controls on oceanic spreading patterns

NASA Astrophysics Data System (ADS)

Gerya, T.

2012-04-01

Mid-ocean ridges sectioned by transform faults represent one of the most prominent surface expressions of terrestrial plate tectonics. A fundamental long standing problem of plate tectonics is how and why ridge-transform spreading patterns are formed and maintained. On the one hand, geometrical correspondence between mid-ocean ridges and respective rifted margins apparently suggests that many oceanic transform faults are inherited structures that persisted throughout the entire history of oceanic spreading. On the other hand, data from incipient oceanic spreading regions show that transform faults are not directly inherited from transverse rift structures and start to develop as or after oceanic spreading nucleate. Based on self-consistent 3D thermomechanical numerical model of oceanic spreading we demonstrate that only limited range of oceanic lithosphere rheologies can reproduce natural spreading patterns. In particular, spontaneous formation and long-term stability of orthogonal ridge-transform spreading pattern requires visco-brittle/plastic rheology of plates with strong dynamic weakening of spontaneously forming faults. Our, numerical models of incipient oceanic spreading demonstrate that one or several oceanic transform faults can form gradually within broad non-transform accommodation zones connecting initially offset spreading centers. Orientation of transform faults and spreading centers changes exponentially with time as the result of new oceanic crust growth. The resulting orthogonal ridge-transform system is established within few millions of years after the beginning of oceanic spreading. By its fundamental physical origin, this system is a crustal growth pattern governed by space accommodation and not a plate breakup pattern governed by stress distribution. It is demonstrated that the characteristic extension-parallel orientation of oceanic transform faults can be obtained from space accommodation criteria as a steady state orientation of a strike-slip fault sustaining in between simultaneously growing offset crustal segments. Numerical models also suggest that transform faults can develop at single straight ridge as the result of dynamical instability of constructive plate boundaries caused by weakening of forming brittle/plastic fractures. Boundary instability from asymmetric plate growth can spontaneously start in alternate directions along successive ridge sections; the resultant curved ridges become transform faults within a few million years. Offsets along the transform faults change continuously with time by asymmetric plate growth and discontinuously by ridge jumps. Degree of asymmetric plate accretion increases with increasing degree of brittle/plastic weakening. It is also strongly dependent on the brittle/plastic yielding criterion and is notably reduced in models with pressure-dependent brittle/plastic plate strength compared to models with pressure-independent strength.

Electron Debye scale Kelvin-Helmholtz instability: Electrostatic particle-in-cell simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Sang-Yun; Lee, Ensang, E-mail: eslee@khu.ac.kr; Kim, Khan-Hyuk

2015-12-15

In this paper, we investigated the electron Debye scale Kelvin-Helmholtz (KH) instability using two-dimensional electrostatic particle-in-cell simulations. We introduced a velocity shear layer with a thickness comparable to the electron Debye length and examined the generation of the KH instability. The KH instability occurs in a similar manner as observed in the KH instabilities in fluid or ion scales producing surface waves and rolled-up vortices. The strength and growth rate of the electron Debye scale KH instability is affected by the structure of the velocity shear layer. The strength depends on the magnitude of the velocity and the growth ratemore » on the velocity gradient of the shear layer. However, the development of the electron Debye scale KH instability is mainly determined by the electric field generated by charge separation. Significant mixing of electrons occurs across the shear layer, and a fraction of electrons can penetrate deeply into the opposite side fairly far from the vortices across the shear layer.« less

Early Life Stress Differentially Modulates Distinct Forms of Brain Plasticity in Young and Adult Mice

PubMed Central

Reichardt, Wilfried; Clark, Kristin; Geiger, Julia; Gross, Claus M.; Heyer, Andrea; Neagu, Valentin; Bhatia, Harsharan; Atas, Hasan C.; Fiebich, Bernd L.; Bischofberger, Josef; Haas, Carola A.; Normann, Claus

2012-01-01

Background Early life trauma is an important risk factor for many psychiatric and somatic disorders in adulthood. As a growing body of evidence suggests that brain plasticity is disturbed in affective disorders, we examined the short-term and remote effects of early life stress on different forms of brain plasticity. Methodology/Principal Findings Mice were subjected to early deprivation by individually separating pups from their dam in the first two weeks after birth. Distinct forms of brain plasticity were assessed in the hippocampus by longitudinal MR volumetry, immunohistochemistry of neurogenesis, and whole-cell patch-clamp measurements of synaptic plasticity. Depression-related behavior was assessed by the forced swimming test in adult animals. Neuropeptides and their receptors were determined by real-time PCR and immunoassay. Early maternal deprivation caused a loss of hippocampal volume, which returned to normal in adulthood. Adult neurogenesis was unaffected by early life stress. Long-term synaptic potentiation, however, was normal immediately after the end of the stress protocol but was impaired in adult animals. In the forced swimming test, adult animals that had been subjected to early life stress showed increased immobility time. Levels of substance P were increased both in young and adult animals after early deprivation. Conclusion Hippocampal volume was affected by early life stress but recovered in adulthood which corresponded to normal adult neurogenesis. Synaptic plasticity, however, exhibited a delayed impairment. The modulation of synaptic plasticity by early life stress might contribute to affective dysfunction in adulthood. PMID:23071534

DOE Office of Scientific and Technical Information (OSTI.GOV)

Niknam, A. R., E-mail: a-niknam@sbu.ac.ir; Rastbood, E.; Khorashadizadeh, S. M.

The dielectric permittivity tensor of a magnetoactive current-driven plasma is obtained by employing the kinetic theory based on the Vlasov equation and Lorentz transformation formulas with an emphasize on the q-nonextensive statistics. By deriving the q-generalized dispersion relation of the low frequency modes in this plasma system, the possibility and properties of filamentation and ion acoustic instabilities are then studied. It is shown that the occurrence and the growth rate of these instabilities depend strongly on the nonextensive parameters, external magnetic field strength, and drift velocity. It is observed that the growth rate of ion acoustic instability is affected bymore » the magnetic field strength much more than that of the filamentation instability in the low frequency range. The external magnetic field facilitates the development of the ion-acoustic instability. It is also shown that the filamentation is the dominant instability only for the high value of drift velocity.« less

Low and high frequency instabilities in an explosion-generated-plasma and possibility of wave triplet

NASA Astrophysics Data System (ADS)

Malik, O. P.; Singh, Sukhmander; Malik, Hitendra K.; Kumar, A.

2015-01-01

An explosion-generated-plasma is explored for low and high frequency instabilities by taking into account the drift of all the plasma species together with the dust particles which are charged. The possibility of wave triplet is also discussed based on the solution of dispersion equation and synchronism conditions. High frequency instability (HFI) and low frequency instability (LFI) are found to occur in this system. LFI grows faster with the higher concentration of dust particles, whereas its growth rate goes down if the mass of the dust is higher. The ion and electron temperatures affect its growth in opposite manner and the electron temperature causes this instability to grow. In addition to the instabilities, a simple wave is also observed to propagate, whose velocity is larger for larger wave number, smaller mass of the dust and higher ion temperature.

Are pulsars spun up or down by SASI spiral modes?

NASA Astrophysics Data System (ADS)

Kazeroni, Rémi; Guilet, Jérôme; Foglizzo, Thierry

2017-10-01

Pulsars may either be spun up or down by hydrodynamic instabilities during the supernova explosion of massive stars. Besides rapidly rotating cases related to bipolar explosions, stellar rotation may affect the explosion of massive stars in the more common situations where the centrifugal force is minor. Using 2D simulations of a simplified set-up in cylindrical geometry, we examine the impact of rotation on the standing accretion shock instability (SASI) and the corotation instability, also known as low-T/|W|. The influence of rotation on the saturation amplitude of these instabilities depends on the specific angular momentum in the accretion flow and the ratio of the shock to the neutron star radii. The spiral mode of SASI becomes more vigorous with faster rotation only if this ratio is large enough. A corotation instability develops at large rotation rates and impacts the dynamics more dramatically, leading to a strong one-armed spiral wave. Non-axisymmetric instabilities are able to redistribute angular momentum radially and affect the pulsar spin at birth. A systematic study of the relationship between the core rotation period of the progenitor and the initial pulsar spin is performed. Stellar rotation rates for which pulsars are spun up or down by SASI are estimated. Rapidly spinning progenitors are modestly spun down by spiral modes, less than ˜30 per cent, when a corotation instability develops. Given the observational constraints on pulsar spin periods at birth, this suggests that rapid rotation might not play a significant hydrodynamic role in most core-collapse supernovae.

Effects of BOSU ball(s) during sit-ups with body weight and added resistance on core muscle activation.

PubMed

Saeterbakken, Atle H; Andersen, Vidar; Jansson, June; Kvellestad, Ann C; Fimland, Marius S

2014-12-01

The objective of this study was to assess the electromyographic activity of the rectus abdominis (upper and lower part) and external oblique during sit-ups performed on BOSU ball(s). Twenty-four men participated in a familiarization session, and in the next session, they performed the experimental tests in randomized order. The sit-ups were performed with 10 repetitions with body weight and with 10 repetition maximum (10RM) using elastic bands as external resistance under 4 different conditions: (a) on a stable surface, (b) with the BOSU ball under their feet (dome side down, lower-body instability), (c) BOSU ball under the low back (dome side up, upper-body instability), and (d) with BOSU balls under both feet and the low back (dual instability). The feet were not attached to the surface. We observed that with body weight, external oblique activation was decreased by upper-body instability and dual instability by 22-24% (p = 0.002-0.006), whereas the rectus abdominis was not affected by the surface. Using 10RM loads, the upper and lower rectus abdominis activities were increased by upper body and dual instability by 21-24% compared with that for a stable surface (P ≤ 0.001-0.036). Further, lower-body instability did not affect muscle activities significantly with either load for any condition. Hence, BOSU balls under the low back can increase and decrease abdominal muscle activation depending on the load, whereas placing a BOSU ball under the feet with the dome side down had little impact.

Solar neutrinos and the influences of opacity, thermal instability, additional neutrino sources, and a central black hole on solar models

NASA Technical Reports Server (NTRS)

Stothers, R. B.; Ezer, D.

1972-01-01

Significant quantities that affect the internal structure of the sun are examined for factors that reduce the temperature near the sun's center. The four factors discussed are: opacity, central black hole, thermal instability, and additional neutrino sources.

New Modelling of Localized Necking in Sheet Metal Stretching

NASA Astrophysics Data System (ADS)

Bressan, José Divo

2011-01-01

Present work examines a new mathematical model to predict the onset of localized necking in the industrial processes of sheet metal forming such as biaxial stretching. Sheet metal formability is usually assessed experimentally by testing such as the Nakajima test to obtain the Forming Limit Curve, FLC, which is an essential material parameter necessary to numerical simulations by FEM. The Forming Limit Diagram or "Forming Principal Strain Map" shows the experimental FLC which is the plot of principal true strains in the sheet metal surface, ɛ1 and ɛ2, occurring at critical points obtained in laboratory formability tests or in the fabrication process. Two types of undesirable rupture mechanisms can occur in sheet metal forming products: localized necking and shear induced fracture. Therefore, two kinds of limit strain curves can be plotted: the local necking limit curve FLC-N and the shear fracture limit curve FLC-S. Localized necking is theoretically anticipated to initiate at a thickness defect ƒin = hib/hia inside the grooved sheet thickness hia, but only at the instability point of maximum load. The inception of grooving on the sheet surface evolves from instability point to localized necking and final rupture, during further sheet metal straining. Work hardening law is defined for a strain and strain rate material by the effective stress σ¯ = σo(1+βɛ¯)n???ɛM. The average experimental hardening law curve for tensile tests at 0°, 45° and 90°, assuming isotropic plasticity, was used to analyze the plasticity behavior during the biaxial stretching of sheet metals. Theoretical predicted curves of local necking limits are plotted in the positive quadrant of FPSM for different defect values ƒin and plasticity parameters. Limit strains are obtained from a software developed by the author. Some experimental results of forming limit curve obtained from experiments for IF steel sheets are compared with the theoretical predicted curves: the correlation is good.

Parsing affective dynamics to identify risk for mood and anxiety disorders.

PubMed

Heller, Aaron S; Fox, Andrew S; Davidson, Richard J

2018-06-04

Emotional dysregulation is thought to underlie risk for both anxiety and depressive disorders. However, despite high rates of comorbidity, anxiety and depression are phenotypically different. Apart from nosological differences (e.g., worry for anxiety, low mood for depression), it remains unclear how the emotional dysregulation inherent in individual differences in trait anxiety and depression severity present on a day-to-day basis. One approach that may facilitate addressing these questions is to utilize Ecological Momentary Assessment (EMA) using mobile phones to parse the temporal dynamics of affective experiences into specific parameters. An emerging literature in affective science suggests that risk for anxiety and depressive disorders may be associated with variation in the mean and instability/variability of emotion. Here we examine the extent to which distinct temporal dynamic parameters uniquely predict risk for anxiety versus depression. Over 10 days, 105 individuals rated their current positive and negative affective state several times each day. Using two distinct approaches to statistically assess mean and instability of positive and negative affect, we found that individual differences in trait anxiety was generally associated with increased instability of positive and negative affect whereas mean levels of positive and negative affect were generally associated with individual differences in depression. These data provide evidence that the emotional dysregulation underlying risk for mood versus anxiety disorders unfolds in distinct ways and highlights the utility in examining affective dynamics to understand psychopathology. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

The Great Wood vs. Plastic Pegboard Controversy: A Definitive Answer

ERIC Educational Resources Information Center

Droege, Robert C.; Hawk, John

1976-01-01

This study was performed to resolve the question of comparability of manual dexterity scores obtained on wooden and plastic versions of the USES pegboard. Currently authorized equipment, either plastic or wooden, may be used with the confidence that scores are not affected by the type of equipment used. (Author)

78 FR 20630 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... Activities; Submission to OMB for Review and Approval; Comment Request; NESHAP for Plastic Parts and Products... www.regulations.gov . Title: NESHAP for Plastic Parts and Products Surface Coating (Renewal). ICR... information; and transmit or otherwise disclose the information. Respondents/Affected Entities: Plastic parts...

Characterization and Prediction of Flow Behavior in High-Manganese Twinning Induced Plasticity Steels: Part II. Jerky Flow and Instantaneous Strain Rate

NASA Astrophysics Data System (ADS)

Saeed-Akbari, A.; Mishra, A. K.; Mayer, J.; Bleck, W.

2012-05-01

The jerky and smooth flow curves in high-manganese twinning induced plasticity (TWIP) steels were investigated by comparing Fe-Mn-C and Fe-Mn-Al-C systems. The pronounced serrations on the flow curves of Fe-Mn-C TWIP steel, produced during tensile testing at 300 K (27 °C) and 373 K (100 °C), were shown to be the result of localized high-temperature Portevin Le-Chatelier (PLC) bands moving across the gage length throughout the deformation. The speed of the PLC bands and their temperature effects were found to be strongly dependent on the applied strain rate, which was controlled by adjusting the cross-head speed of the tensile testing machine. The localized temperature-dependent stacking fault energy (SFE) variations resulting from the PLC effect and adiabatic heating were analyzed and compared for both slow and fast deformation rates. The instabilities in the measured logarithmic strain values caused by jerky flow could cause the local strain rate to deviate systematically from the targeted (applied) strain rate. These instabilities are better observed by calculating the instantaneous strain rate (ISR) values for each instant of deformation along the entire gage length. Finally, a new type of diagram was developed by plotting the true stress against the ISR values. From the diagram, the onset of different mechanisms, such as deformation twinning, nonpronounced, and pronounced serrations, could be marked precisely.

Damage of Elastomeric Matrix Composites (EMC-rubbers) Under Static Loading Conditions: Experimental and Numerical Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ayari, F.; Supmeca/LISMMA-Paris, School of Mechanical and Manufacturing Engineering; Bayraktar, E.

2011-01-17

Elastomeric matrix composites (EMC-rubbers) are considered as isotropic hyper elastic incompressible materials under static loading conditions. As a rubber material element cannot be extended to an infinite stretch ratio, a damage mechanism at large strain is considered. The phenomenon of cavitation plays an important role in the damage of EMCs and influences the toughening mechanism of rubber-modified plastics. Indeed, cavitation in elastomers is thought to be initiated from flaws, which grow primarily due to a hydrostatic tensile stress and ahead of the crack; there will not only be a high stress perpendicular to the plane of the crack but alsomore » significant stress components in the other direction. However, there exists historically much discussion on the evolution of the cavitation in elastomers under monotonic and/or static solicitation. Mainly, cavitation instability occurs when the stress levels are sufficiently high so that the void expansion rate becomes infinitely large. Many research works have been performed to understand the effects of rubber cavitation on toughening of plastics. In fact, the cavitation phenomenon is not well known in detail. The most popular idea states that the cavitation is related to the existence of the gas bubbles trapped in the material during the production stage and the growing of the cavities would then be the result of the growing gas bubbles. Further, instable failure mechanism at the end of the cavitation is not well known too.« less

Interstitial atoms enable joint twinning and transformation induced plasticity in strong and ductile high-entropy alloys.

PubMed

Li, Zhiming; Tasan, Cemal Cem; Springer, Hauke; Gault, Baptiste; Raabe, Dierk

2017-01-12

High-entropy alloys (HEAs) consisting of multiple principle elements provide an avenue for realizing exceptional mechanical, physical and chemical properties. We report a novel strategy for designing a new class of HEAs incorporating the additional interstitial element carbon. This results in joint activation of twinning- and transformation-induced plasticity (TWIP and TRIP) by tuning the matrix phase's instability in a metastable TRIP-assisted dual-phase HEA. Besides TWIP and TRIP, such alloys benefit from massive substitutional and interstitial solid solution strengthening as well as from the composite effect associated with its dual-phase structure. Nanosize particle formation and grain size reduction are also utilized. The new interstitial TWIP-TRIP-HEA thus unifies all metallic strengthening mechanisms in one material, leading to twice the tensile strength compared to a single-phase HEA with similar composition, yet, at identical ductility.

Ductile fracture theories for pressurised pipes and containers

NASA Technical Reports Server (NTRS)

Erdogan, F.

1976-01-01

Two mechanisms of fracture are distinguished. Plane strain fractures occur in materials which do not undergo large-scale plastic deformations prior to and during a possible fracture deformation. Plane stress or high energy fractures are generally accompanied by large inelastic deformations. Theories for analyzing plane stress are based on the concepts of critical crack opening stretch, K(R) characterization, J-integral, and plastic instability. This last is considered in some detail. The ductile fracture process involves fracture initiation followed by a stable crack growth and the onset of unstable fracture propagation. The ductile fracture propagation process may be characterized by either a multiparameter (discrete) model, or some type of a resistance curve which may be considered as a continuous model expressed graphically. These models are studied and an alternative model is also proposed for ductile fractures which cannot be modeled as progressive crack growth phenomena.

Prediction Of Formability In Sheet Metal Forming Processes Using A Local Damage Model

NASA Astrophysics Data System (ADS)

Teixeira, P.; Santos, Abel; César Sá, J.; Andrade Pires, F.; Barata da Rocha, A.

2007-05-01

The formability in sheet metal forming processes is mainly conditioned by ductile fracture resulting from geometric instabilities due to necking and strain localization. The macroscopic collapse associated with ductile failure is a result of internal degradation described throughout metallographic observations by the nucleation, growth and coalescence of voids and micro-cracks. Damage influences and is influenced by plastic deformation and therefore these two dissipative phenomena should be coupled at the constitutive level. In this contribution, Lemaitre's ductile damage model is coupled with Hill's orthotropic plasticity criterion. The coupling between damaging and material behavior is accounted for within the framework of Continuum Damage Mechanics (CDM). The resulting constitutive equations are implemented in the Abaqus/Explicit code, for the prediction of fracture onset in sheet metal forming processes. The damage evolution law takes into account the important effect of micro-crack closure, which dramatically decreases the rate of damage growth under compressive paths.

Rapid prototyping to design a customized locking plate for pancarpal arthrodesis in a giant breed dog.

PubMed

Petazzoni, M; Nicetto, T

2014-01-01

This report describes the treatment of traumatic carpal hyperextension in a giant breed dog by pancarpal arthrodesis using a custom-made Fixin locking plate, created with the aid of a three-dimensional plastic model of the bones of the antebrachium produced by rapid prototyping technology. A three-year-old 104 kg male Mastiff dog was admitted for treatment of carpal hyperextension injury. After diagnosis of carpal instability, surgery was recommended. Computed tomography images were used to create a life-size three-dimensional plastic model of the forelimb. The model was used as the basis for constructing a customized 12-hole Fixin locking plate. The plate was used to attain successful pancarpal arthrodesis in the animal. Radiographic examination after 74 and 140 days revealed signs of osseous union of the arthrodesis. Further clinical and radiographic follow-up examination three years later did not reveal any changes in implant position or complications.

Interstitial atoms enable joint twinning and transformation induced plasticity in strong and ductile high-entropy alloys

NASA Astrophysics Data System (ADS)

Li, Zhiming; Tasan, Cemal Cem; Springer, Hauke; Gault, Baptiste; Raabe, Dierk

2017-01-01

High-entropy alloys (HEAs) consisting of multiple principle elements provide an avenue for realizing exceptional mechanical, physical and chemical properties. We report a novel strategy for designing a new class of HEAs incorporating the additional interstitial element carbon. This results in joint activation of twinning- and transformation-induced plasticity (TWIP and TRIP) by tuning the matrix phase’s instability in a metastable TRIP-assisted dual-phase HEA. Besides TWIP and TRIP, such alloys benefit from massive substitutional and interstitial solid solution strengthening as well as from the composite effect associated with its dual-phase structure. Nanosize particle formation and grain size reduction are also utilized. The new interstitial TWIP-TRIP-HEA thus unifies all metallic strengthening mechanisms in one material, leading to twice the tensile strength compared to a single-phase HEA with similar composition, yet, at identical ductility.

Biodegradability of plastics.

PubMed

Tokiwa, Yutaka; Calabia, Buenaventurada P; Ugwu, Charles U; Aiba, Seiichi

2009-08-26

Plastic is a broad name given to different polymers with high molecular weight, which can be degraded by various processes. However, considering their abundance in the environment and their specificity in attacking plastics, biodegradation of plastics by microorganisms and enzymes seems to be the most effective process. When plastics are used as substrates for microorganisms, evaluation of their biodegradability should not only be based on their chemical structure, but also on their physical properties (melting point, glass transition temperature, crystallinity, storage modulus etc.). In this review, microbial and enzymatic biodegradation of plastics and some factors that affect their biodegradability are discussed.

Biodegradability of Plastics

PubMed Central

Tokiwa, Yutaka; Calabia, Buenaventurada P.; Ugwu, Charles U.; Aiba, Seiichi

2009-01-01

Plastic is a broad name given to different polymers with high molecular weight, which can be degraded by various processes. However, considering their abundance in the environment and their specificity in attacking plastics, biodegradation of plastics by microorganisms and enzymes seems to be the most effective process. When plastics are used as substrates for microorganisms, evaluation of their biodegradability should not only be based on their chemical structure, but also on their physical properties (melting point, glass transition temperature, crystallinity, storage modulus etc.). In this review, microbial and enzymatic biodegradation of plastics and some factors that affect their biodegradability are discussed. PMID:19865515

Microplastics and Nanoplastics in Aquatic Environments: Aggregation, Deposition, and Enhanced Contaminant Transport.

PubMed

Alimi, Olubukola S; Farner Budarz, Jeffrey; Hernandez, Laura M; Tufenkji, Nathalie

2018-02-20

Plastic litter is widely acknowledged as a global environmental threat, and poor management and disposal lead to increasing levels in the environment. Of recent concern is the degradation of plastics from macro- to micro- and even to nanosized particles smaller than 100 nm in size. At the nanoscale, plastics are difficult to detect and can be transported in air, soil, and water compartments. While the impact of plastic debris on marine and fresh waters and organisms has been studied, the loads, transformations, transport, and fate of plastics in terrestrial and subsurface environments are largely overlooked. In this Critical Review, we first present estimated loads of plastics in different environmental compartments. We also provide a critical review of the current knowledge vis-à-vis nanoplastic (NP) and microplastic (MP) aggregation, deposition, and contaminant cotransport in the environment. Important factors that affect aggregation and deposition in natural subsurface environments are identified and critically analyzed. Factors affecting contaminant sorption onto plastic debris are discussed, and we show how polyethylene generally exhibits a greater sorption capacity than other plastic types. Finally, we highlight key knowledge gaps that need to be addressed to improve our ability to predict the risks associated with these ubiquitous contaminants in the environment by understanding their mobility, aggregation behavior and their potential to enhance the transport of other pollutants.

Factors Affecting the Discharge of Micro-Plastic Fibers from Household Laundry

NASA Astrophysics Data System (ADS)

Lange, N.

2017-12-01

Every day millions of loads of laundry are done in in the United States alone. Many, if not most, include synthetic fibers. During washing, micro-plastic fibers are released from the fabric, and discharged into the wastewater. These fibers have been detected in fresh water throughout the world and all of the oceans. These micro-plastic fibers are an emerging environmental contaminant that can adversely affect wildlife and are highly bio-accumulated in aquatic food-chains. Additionally, like other plastics, micro-fibers are not readily biodegraded and persist in the environment for a long time. In this research, I explored the effect of the way we wash clothes on the amount of micro-plastic fibers that are shed by common clothing materials containing man-made fibers. I collected discharge samples from wash and rinse cycles of a washing machine. I collected samples from a control wash using no detergent and then repeated five times. Next, I repeated the experiment five times using four different types of detergent. Large amounts of micro-plastic fibers were released during all wash cycles. However, the numbers decreased during the later rinse cycles. The use of laundry detergent increased the number of micro-plastic fibers released into the wash-water. Deep cleaning detergents produced over ten times more fibers than the no-detergent control. The gentlest detergent only released two times more fibers than the control. Therefore, it would be possible to affect the number of fibers released into the wastewater simply by selection of detergent. The ultimate goal of my research is to develop an optimized detergent that minimizes the number of micro-plastic fibers generated by washing and still effectively clean clothes.

Plasticity as Phenotype: G x E Interaction in a Freshwater Snail

NASA Astrophysics Data System (ADS)

Brunkow, P. E.; Calloway, S. A.

2005-05-01

Plasticity in morphological development allows species to accommodate environmental variation experienced during growth; however, genetic variation for phenotypic plasticity per se has been relatively under-studied. We utilized the well-documented plastic response of shell development to predator cues in a freshwater snail to quantify genetic variation for plasticity in growth rate and shell shape. Field-caught pairs of snails reproduced in the laboratory to create families of full siblings, which were then divided and allowed to grow in control and predator cue treatments. Predator (crayfish) cues had significant effects on both size-corrected growth rate and shell shape; family identity also significantly affected both final shell shape and growth rate. The interaction between predator treatment and family identity significantly affected snail growth rate but not final shell shape, suggesting genetic variation in the plastic response to predator cues for a physiological variable (growth rate) but not for a variable known to mechanically reduce the risk of predation (shell shape), at least in this population of snails. The possibility that risk of multiple modes of predation (i.e., both fish and crayfish) in some populations might maintain genetic variation in morphological plasticity is discussed.

Affect dynamics in relation to depressive symptoms: variable, unstable or inert?

PubMed

Koval, Peter; Pe, Madeline L; Meers, Kristof; Kuppens, Peter

2013-12-01

Depression not only involves disturbances in prevailing affect, but also in how affect fluctuates over time. Yet, precisely which patterns of affect dynamics are associated with depressive symptoms remains unclear; depression has been linked with increased affective variability and instability, but also with greater resistance to affective change (inertia). In this paper, we argue that these paradoxical findings stem from a number of neglected methodological/analytical factors, which we address using a novel paradigm and analytic approach. Participants (N = 99), preselected to represent a wide range of depressive symptoms, watched a series of emotional film clips and rated their affect at baseline and following each film clip. We also assessed participants' affect in daily life over 1 week using experience sampling. When controlling for overlap between different measures of affect dynamics, depressive symptoms were independently associated with higher inertia of negative affect in the lab, and with greater negative affect variability both in the lab and in daily life. In contrast, depressive symptoms were not independently related to higher affective instability either in daily life or in the lab.

Review of Inertial Confinement Fusion

NASA Astrophysics Data System (ADS)

Haines, M. G.

The physics of inertial confinement fusion is reviewed. The trend to short-wavelength lasers is argued, and the distinction between direct and indirect (soft X-ray) drive is made. Key present issues include the non-linear growth of Rayleigh-Taylor (R-T) instabilities, the seeding of this instability by the initial laser imprint, the relevance of self-generated magnetic fields, and the importance of parametric instabilities (stimulated Brillouin and Raman scattering) in gas-filled hohlraums. Experiments are reviewed which explore the R-T instability in both planar and converging geometry. The employment of various optical smoothing techniques is contrasted with the overcoating of the capsule by gold coated plastic foams to reduce considerably the imprint problem. The role of spontaneously generated magnetic fields in non-symmetric plasmas is discussed. Recent hohlraum compression results are presented together with gas bag targets which replicate the long-scale-length low density plasmas expected in NIF gas filled hohlraums. The onset of first Brillouin and then Raman scattering is observed. The fast ignitor scheme is a proposal to use an intense short pulse laser to drill a hole through the coronal plasma and then, with laser excited fast electrons, create a propagating thermonuclear spark in a dense, relatively cold laser-compressed target. Some preliminary results of laser hole drilling and 2-D and 3-D PIC simulations of this and the > 10^8 Gauss self-generated magnetic fields are presented. The proposed National Ignition Facility (NIF) is described.

Effects of differentiation on the geodynamics of the early Earth

NASA Astrophysics Data System (ADS)

Piccolo, Andrea; Kaus, Boris; White, Richard; Johnson, Tim

2016-04-01

Archean geodynamic processes are not well understood, but there is general agreement that the mantle potential temperature was higher than present, and that as a consequence significant amounts of melt were produced both in the mantle and any overlying crust. This has likely resulted in crustal differentiation. An early attempt to model the geodynamic effects of differentiation was made by Johnson et al. (2014), who used numerical modeling to investigate the crust production and recycling in conjunction with representative phase diagrams (based on the inferred chemical composition of the primary melt in accordance with the Archean temperature field). The results of the simulations show that the base of the over-thickened primary basaltic crust becomes gravitational unstable due to the mineral assemblage changes. This instability leads to the dripping of dense material into the mantle, which causes an asthenospheric return flow, local partial melting and new primary crust generation that is rapidly recycled in to mantle. Whereas they gave important insights, the previous simulations were simplified in a number of aspects: 1) the rheology employed was viscous, and both elasticity and pressure-dependent plasticity were not considered; 2) extracted mantle melts were 100% transformed into volcanic rocks, whereas on the present day Earth only about 20-30% are volcanic and the remainder is plutonic; 3) the effect of a free surface was not studied in a systematic manner. In order to better understand how these simplifications affect the geodynamic models, we here present additional simulations to study the effects of each of these parameters. Johnson, T.E., Brown, M., Kaus, B., and VanTongeren, J.A., 2014, Delamination and recycling of Archaean crust caused by gravitational instabilities: Nature Geoscience, v. 7, no. 1, p. 47-52, doi: 10.1038/NGEO2019.

Methods and compositions for protection of cells and tissues from computed tomography radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grdina, David J.

Described are methods for preventing or inhibiting genomic instability and in cells affected by diagnostic radiology procedures employing ionizing radiation. Embodiments include methods of preventing or inhibiting genomic instability and in cells affected by computed tomography (CT) radiation. Subjects receiving ionizing radiation may be those persons suspected of having cancer, or cancer patients having received or currently receiving cancer therapy, and or those patients having received previous ionizing radiation, including those who are approaching or have exceeded the recommended total radiation dose for a person.

A Comparison of Single-Cycle Versus Multiple-Cycle Proof Testing Strategies

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Millwater, H. R.; Russell, D. A.; Millwater, H. R.

1999-01-01

Single-cycle and multiple-cycle proof testing (SCPT and MCPT) strategies for reusable aerospace propulsion system components are critically evaluated and compared from a rigorous elastic-plastic fracture mechanics perspective. Earlier MCPT studies are briefly reviewed. New J-integral estimation methods for semielliptical surface cracks and cracks at notches are derived and validated. Engineering methods are developed to characterize crack growth rates during elastic-plastic fatigue crack growth (FCG) and the tear-fatigue interaction near instability. Surface crack growth experiments are conducted with Inconel 718 to characterize tearing resistance, FCG under small-scale yielding and elastic-plastic conditions, and crack growth during simulated MCPT. Fractography and acoustic emission studies provide additional insight. The relative merits of SCPT and MCPT are directly compared using a probabilistic analysis linked with an elastic-plastic crack growth computer code. The conditional probability of failure in service is computed for a population of components that have survived a previous proof test, based on an assumed distribution of initial crack depths. Parameter studies investigate the influence of proof factor, tearing resistance, crack shape, initial crack depth distribution, and notches on the MCPT versus SCPT comparison. The parameter studies provide a rational basis to formulate conclusions about the relative advantages and disadvantages of SCPT and MCPT. Practical engineering guidelines are proposed to help select the optimum proof test protocol in a given application.

A Comparison of Single-Cycle Versus Multiple-Cycle Proof Testing Strategies

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Millwater, H. R.; Russell, D. A.; Orient, G. E.

1996-01-01

Single-cycle and multiple-cycle proof testing (SCPT and MCPT) strategies for reusable aerospace propulsion system components are critically evaluated and compared from a rigorous elastic-plastic fracture mechanics perspective. Earlier MCPT studies are briefly reviewed. New J-integral estimation methods for semi-elliptical surface cracks and cracks at notches are derived and validated. Engineering methods are developed to characterize crack growth rates during elastic-plastic fatigue crack growth (FCG) and the tear-fatigue interaction near instability. Surface crack growth experiments are conducted with Inconel 718 to characterize tearing resistance, FCG under small-scale yielding and elastic-plastic conditions, and crack growth during simulated MCPT. Fractography and acoustic emission studies provide additional insight. The relative merits of SCPT and MCPT are directly compared using a probabilistic analysis linked with an elastic-plastic crack growth computer code. The conditional probability of failure in service is computed for a population of components that have survived a previous proof test, based on an assumed distribution of initial crack depths. Parameter studies investigate the influence of proof factor, tearing resistance, crack shape, initial crack depth distribution, and notches on the MCPT vs. SCPT comparison. The parameter studies provide a rational basis to formulate conclusions about the relative advantages and disadvantages of SCPT and MCPT. Practical engineering guidelines are proposed to help select the optimum proof test protocol in a given application.

Fabric and connectivity as field descriptors for deformations in granular media

NASA Astrophysics Data System (ADS)

Wan, Richard; Pouragha, Mehdi

2015-01-01

Granular materials involve microphysics across the various scales giving rise to distinct behaviours of geomaterials, such as steady states, plastic limit states, non-associativity of plastic and yield flow, as well as instability of homogeneous deformations through strain localization. Incorporating such micro-scale characteristics is one of the biggest challenges in the constitutive modelling of granular materials, especially when micro-variables may be interdependent. With this motivation, we use two micro-variables such as coordination number and fabric anisotropy computed from tessellation of the granular material to describe its state at the macroscopic level. In order to capture functional dependencies between micro-variables, the correlation between coordination number and fabric anisotropy limits is herein formulated at the particle level rather than on an average sense. This is the essence of the proposed work which investigates the evolutions of coordination number distribution (connectivity) and anisotropy (contact normal) distribution curves with deformation history and their inter-dependencies through discrete element modelling in two dimensions. These results enter as probability distribution functions into homogenization expressions during upscaling to a continuum constitutive model using tessellation as an abstract representation of the granular system. The end product is a micro-mechanically inspired continuum model with both coordination number and fabric anisotropy as underlying micro-variables incorporated into a plasticity flow rule. The derived plastic potential bears striking resemblance to cam-clay or stress-dilatancy-type yield surfaces used in soil mechanics.

Insights into the genomic plasticity of Pseudomonas putida KF715, a strain with unique biphenyl-utilizing activity and genome instability properties.

PubMed

Suenaga, Hikaru; Fujihara, Hidehiko; Kimura, Nobutada; Hirose, Jun; Watanabe, Takahito; Futagami, Taiki; Goto, Masatoshi; Shimodaira, Jun; Furukawa, Kensuke

2017-10-01

Pseudomonas putida KF715 exhibits unique properties in both catabolic activity and genome plasticity. Our previous studies revealed that the DNA region containing biphenyl and salycilate metabolism gene clusters (termed the bph-sal element) was frequently deleted and transferred by conjugation to closely related P. putida strains. In this study, we first determined the complete nucleotide sequence of the KF715 genome. Next, to determine the underlying cause of genome plasticity in KF715, we compared the KF715 genome with the genomes of one KF715 defective mutant, two transconjugants, and several P. putida strains available from public databases. The gapless KF715 genome sequence revealed five replicons: one circular chromosome, and four plasmids. Southern blot analysis indicated that most of the KF715 cell population carries the bph-sal element on the chromosome whereas a small number carry it on a huge plasmid, pKF715A. Moreover, the bph-sal element is present stably on the plasmid and did not integrate into the chromosome of its transconjugants. Comparative genome analysis and experiments showed that a number of diverse putative genetic elements are present in KF715 and are likely involved in genome rearrangement. These data provide insights into the genetic plasticity and adaptability of microorganisms for survival in various ecological niches. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

Physical nature of strain rate sensitivity of metals and alloys at high strain rates

NASA Astrophysics Data System (ADS)

Borodin, E. N.; Gruzdkov, A. A.; Mayer, A. E.; Selyutina, N. S.

2018-04-01

The role of instabilities of plastic flow at plastic deformation of various materials is one of the important cross-disciplinary problems which is equally important in physics, mechanics and material science. The strain rate sensitivities under slow and high strain rate conditions of loading have different physical nature. In the case of low strain rate, the sensitivity arising from the inertness of the defect structures evolution can be expressed by a single parameter characterizing the plasticity mechanism. In our approach, this is the value of the characteristic relaxation time. In the dynamic case, there are additional effects of “high-speed sensitivity” associated with the micro-localization of the plastic flow near the stress concentrators. In the frames of mechanical description, this requires to introduce additional strain rate sensitivity parameters, which is realized in numerous modifications of Johnson–Cook and Zerilli–Armstrong models. The consideration of both these factors is fundamental for an adequate description of the problems of dynamic deformation of highly inhomogeneous metallic materials such as steels and alloys. The measurement of the dispersion of particle velocities on the free surface of a shock-loaded material can be regarded as an experimental expression of the effect of micro-localization. This is also confirmed by our results of numerical simulation of the propagation of shock waves in a two-dimensional formulation and analytical estimations.

[External stability of the elbow after surgical treatment of epicondylitis. Presentation of a case].

PubMed

Llop-Corbacho, A; Romero-Ruiz, J; Denia-Alarcón, N

2014-01-01

Elbow instability is a difficult to diagnose condition in certain cases, and could lead to some problems that limit daily functioning, such as joint blocks, bumps, projections, muscle weakness, and persistent pain. A case is presented of a patient with a clinical picture of epicondylitis, with a previous history of a fall on the affected arm. As there was no improvement after performing conventional non-aggressive treatment, surgery was performed on the affected tendon. The outcome of this was persistent pain and clinical instability of the elbow that ended up requiring surgery to reconstruct the ligament over the external complex. In follow-up 6 months after the operation, the clinical instability had disappeared, but there was still external discomfort and a 30° extension deficit. When faced with a picture of epicondylitis with a previous injury that does not respond to conventional therapies, it is important to take into account the possibility of an underlying elbow instability, ruling this out with a correct physical examination and, where necessary, with the appropriate complementary tests. Copyright © 2013 SECOT. Published by Elsevier Espana. All rights reserved.

Will phenotypic plasticity affecting flowering phenology keep pace with climate change?

Treesearch

Bryce A. Richardson; Linsay Chaney; Nancy L. Shaw; Shannon M. Still

2016-01-01

Rising temperatures have begun to shift flowering time, but it is unclear whether phenotypic plasticity can accommodate projected temperature change for this century. Evaluating clines in phenological traits and the extent and variation in plasticity can provide key information on assessing risk of maladaptation and developing strategies to mitigate climate change. In...

Diet and cognition: interplay between cell metabolism and neuronal plasticity.

PubMed

Gomez-Pinilla, Fernando; Tyagi, Ethika

2013-11-01

To discuss studies in humans and animals revealing the ability of foods to benefit the brain: new information with regards to mechanisms of action and the treatment of neurological and psychiatric disorders. Dietary factors exert their effects on the brain by affecting molecular events related to the management of energy metabolism and synaptic plasticity. Energy metabolism influences neuronal function, neuronal signaling, and synaptic plasticity, ultimately affecting mental health. Epigenetic regulation of neuronal plasticity appears as an important mechanism by which foods can prolong their effects on long-term neuronal plasticity. The prime focus of the discussion is to emphasize the role of cell metabolism as a mediator for the action of foods on the brain. Oxidative stress promotes damage to phospholipids present in the plasma membrane such as the omega-3 fatty acid docosahexenoic acid, disrupting neuronal signaling. Thus, dietary docosahexenoic acid seems crucial for supporting plasma membrane function, interneuronal signaling, and cognition. The dual action of brain-derived neurotrophic factor in neuronal metabolism and synaptic plasticity is crucial for activating signaling cascades under the action of diet and other environmental factors, using mechanisms of epigenetic regulation.

Advances in Discrete Dislocation Dynamics Modeling of Size-Affected Plasticity

NASA Astrophysics Data System (ADS)

El-Awady, Jaafar A.; Fan, Haidong; Hussein, Ahmed M.

In dislocation-mediated plasticity of crystalline materials, discrete dislocation dynamics (DDD) methods have been widely used to predict the plastic deformation in a number of technologically important problems. These simulations have led to significant improvement in the understanding of the different mechanism that controls the mechanical properties of crystalline materials, which can greatly accelerate the future development of materials with superior properties. This chapter provides an overview of different practical applications of both two-dimensional and three-dimensional DDD simulations in the field of size-affected dislocation-mediated plasticity. The chapter is divided into two major tracks. First, DDD simulations focusing on aspects of modeling size-dependent plasticity in single crystals in uniaxial micro-compression/tension, microtorsion, microbending, and nanoindentation are discussed. Special attention is directed towards the role of cross-slip and dislocation nucleation on the overall response. Second, DDD simulations focusing on the role of interfaces, including grain and twin boundaries, on dislocation-mediated plasticity are discussed. Finally, a number of challenges that are withholding DDD simulations from reaching their full potential are discussed.

An analytical hierarchy process-based study on the factors affecting legislation on plastic bags in the USA.

PubMed

Li, Zhongguo; Zhao, Fu

2017-08-01

Annually, a large number of used plastic shopping bags are released into the environment, posing significant threats to public health and wildlife. Owing to these concerns, many local, regional, and national governments around the world have passed legislation to ban or restrict the use of plastic shopping bags. However, in the USA there are only 18 states that have approved plastic bag bans/fees, and even within these states these regulations do not cover all cities or counties. There are many factors that could affect the development and implementation of these regulations. This article employs an analytical hierarchy process to analyse the factors that could impact the enactment of plastic bag regulations. Five impact factors are identified based on statistical data, that is, geographical location, interest of industry achievable, cost of living, level of economic development, and educational level of population. The weights of the five impact factors are determined and it is found that the possibility of banning or restricting plastic bags in general follows a certain pattern among all states.

Numerical analysis of the effect of surface roughness on mechanical fields in polycrystalline aggregates

NASA Astrophysics Data System (ADS)

Guilhem, Yoann; Basseville, Stéphanie; Curtit, François; Stéphan, Jean-Michel; Cailletaud, Georges

2018-06-01

This paper is dedicated to the study of the influence of surface roughness on local stress and strain fields in polycrystalline aggregates. Finite element computations are performed with a crystal plasticity model on a 316L stainless steel polycrystalline material element with different roughness states on its free surface. The subsequent analysis of the plastic strain localization patterns shows that surface roughness strongly affects the plastic strain localization induced by crystallography. Nevertheless, this effect mainly takes place at the surface and vanishes under the first layer of grains, which implies the existence of a critical perturbed depth. A statistical analysis based on the plastic strain distribution obtained for different roughness levels provides a simple rule to define the size of the affected zone depending on the rough surface parameters.

Elimination of a Photovoltaic Induced Fast Instability in Photorefractive Iron-doped Lithium Niobate Crystals

NASA Astrophysics Data System (ADS)

Evans, D. R.; Saleh, M. A.; Allen, A. S.; Pottenger, T. P.; Bunning, T. J.; Guha, S.; Basun, S. A.; Cook, G.

2002-03-01

An instability on the order of 10 ns is observed while writing volume gratings in bulk crystals of iron-doped lithium niobate using contra-directional two-beam coupling along the c-axis. This instability is attributed to the quasi-breakdown of the uniform component of the photovoltaic field [1], which affects the uniform electric field formed inside the crystal causing a change in the refractive index through the electro-optic effect. A method to eliminate this instability by coating the z-surfaces of the crystal with a transparent conductive coating will be presented. [1] A. Krumins, Z. Chen, and T. Shiosaki, Opt. Comm. 117 (1995) 147-150.

Health coverage instability for mothers in working families.

PubMed

Anderson, Steven G; Eamon, Mary Keegan

2004-07-01

Using data from the National Longitudinal Survey of Youth, the authors examined the health insurance coverage stability of 1,667 women in working families over a three-year period (1995-1997). Findings revealed that coverage instability is common. Nearly one-half of low-income women experienced health coverage instability over the three-year study period, and low-income women with poor education, single marital status, low work hours, and frequent job changes were at even greater risk of coverage instability. The findings also imply that women affected by recent welfare reforms are likely to experience widespread health coverage problems. The implications for health care policy development, social work administration, and social work practice are discussed.

A patient with polymerase E1 deficiency (POLE1): clinical features and overlap with DNA breakage/instability syndromes.

PubMed

Thiffault, Isabelle; Saunders, Carol; Jenkins, Janda; Raje, Nikita; Canty, Kristi; Sharma, Mukta; Grote, Lauren; Welsh, Holly I; Farrow, Emily; Twist, Greyson; Miller, Neil; Zwick, David; Zellmer, Lee; Kingsmore, Stephen F; Safina, Nicole P

2015-05-07

Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage, often leading to immunodeficiency, growth retardation and increased risk of malignancy. We performed exome sequencing on a girl with a suspected chromosome instability syndrome that manifested as growth retardation, microcephaly, developmental delay, dysmorphic features, poikiloderma, immune deficiency with pancytopenia, and myelodysplasia. She was homozygous for a previously reported splice variant, c.4444 + 3A > G in the POLE1 gene, which encodes the catalytic subunit of DNA polymerase E. This is the second family with POLE1-deficency, with the affected individual demonstrating a more severe phenotype than previously described.

Systematic review of postural control and lateral ankle instability, part I: can deficits be detected with instrumented testing.

PubMed

McKeon, Patrick O; Hertel, Jay

2008-01-01

To answer the following clinical questions: (1) Is poor postural control associated with increased risk of a lateral ankle sprain? (2) Is postural control adversely affected after acute lateral ankle sprain? (3) Is postural control adversely affected in those with chronic ankle instability? PubMed and CINAHL entries from 1966 through October 2006 were searched using the terms ankle sprain, ankle instability, balance, chronic ankle instability, functional ankle instability, postural control, and postural sway. Only studies assessing postural control measures in participants on a stable force plate performing the modified Romberg test were included. To be included, a study had to address at least 1 of the 3 clinical questions stated above and provide adequate results for calculation of effect sizes or odds ratios where applicable. We calculated odds ratios with 95% confidence intervals for studies assessing postural control as a risk factor for lateral ankle sprains. Effect sizes were estimated with the Cohen d and associated 95% confidence intervals for comparisons of postural control performance between healthy and injured groups, or healthy and injured limbs, respectively. Poor postural control is most likely associated with an increased risk of sustaining an acute ankle sprain. Postural control is impaired after acute lateral ankle sprain, with deficits identified in both the injured and uninjured sides compared with controls. Although chronic ankle instability has been purported to be associated with altered postural control, these impairments have not been detected consistently with the use of traditional instrumented measures. Instrumented postural control testing on stable force plates is better at identifying deficits that are associated with an increased risk of ankle sprain and that occur after acute ankle sprains than at detecting deficits related to chronic ankle instability.

Pms2 Suppresses Large Expansions of the (GAA·TTC)n Sequence in Neuronal Tissues

PubMed Central

Bourn, Rebecka L.; De Biase, Irene; Pinto, Ricardo Mouro; Sandi, Chiranjeevi; Al-Mahdawi, Sahar; Pook, Mark A.; Bidichandani, Sanjay I.

2012-01-01

Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in postmitotic tissues is consistent with DNA repair being a major determinant of somatic instability. Indeed, proteins in the mismatch repair (MMR) pathway are required for instability of the expanded (CAG·CTG)n sequence, likely via recognition of intrastrand hairpins by MutSβ. It is not clear if or how MMR would affect instability of disease-causing expanded trinucleotide repeat sequences that adopt secondary structures other than hairpins, such as the triplex/R-loop forming (GAA·TTC)n sequence that causes Friedreich ataxia. We analyzed somatic instability in transgenic mice that carry an expanded (GAA·TTC)n sequence in the context of the human FXN locus and lack the individual MMR proteins Msh2, Msh6 or Pms2. The absence of Msh2 or Msh6 resulted in a dramatic reduction in somatic mutations, indicating that mammalian MMR promotes instability of the (GAA·TTC)n sequence via MutSα. The absence of Pms2 resulted in increased accumulation of large expansions in the nervous system (cerebellum, cerebrum, and dorsal root ganglia) but not in non-neuronal tissues (heart and kidney), without affecting the prevalence of contractions. Pms2 suppressed large expansions specifically in tissues showing MutSα-dependent somatic instability, suggesting that they may act on the same lesion or structure associated with the expanded (GAA·TTC)n sequence. We conclude that Pms2 specifically suppresses large expansions of a pathogenic trinucleotide repeat sequence in neuronal tissues, possibly acting independently of the canonical MMR pathway. PMID:23071719

Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues.

PubMed

Bourn, Rebecka L; De Biase, Irene; Pinto, Ricardo Mouro; Sandi, Chiranjeevi; Al-Mahdawi, Sahar; Pook, Mark A; Bidichandani, Sanjay I

2012-01-01

Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in postmitotic tissues is consistent with DNA repair being a major determinant of somatic instability. Indeed, proteins in the mismatch repair (MMR) pathway are required for instability of the expanded (CAG·CTG)(n) sequence, likely via recognition of intrastrand hairpins by MutSβ. It is not clear if or how MMR would affect instability of disease-causing expanded trinucleotide repeat sequences that adopt secondary structures other than hairpins, such as the triplex/R-loop forming (GAA·TTC)(n) sequence that causes Friedreich ataxia. We analyzed somatic instability in transgenic mice that carry an expanded (GAA·TTC)(n) sequence in the context of the human FXN locus and lack the individual MMR proteins Msh2, Msh6 or Pms2. The absence of Msh2 or Msh6 resulted in a dramatic reduction in somatic mutations, indicating that mammalian MMR promotes instability of the (GAA·TTC)(n) sequence via MutSα. The absence of Pms2 resulted in increased accumulation of large expansions in the nervous system (cerebellum, cerebrum, and dorsal root ganglia) but not in non-neuronal tissues (heart and kidney), without affecting the prevalence of contractions. Pms2 suppressed large expansions specifically in tissues showing MutSα-dependent somatic instability, suggesting that they may act on the same lesion or structure associated with the expanded (GAA·TTC)(n) sequence. We conclude that Pms2 specifically suppresses large expansions of a pathogenic trinucleotide repeat sequence in neuronal tissues, possibly acting independently of the canonical MMR pathway.

Stability of surface plastic flow in large strain deformation of metals

NASA Astrophysics Data System (ADS)

Viswanathan, Koushik; Udapa, Anirduh; Sagapuram, Dinakar; Mann, James; Chandrasekar, Srinivasan

We examine large-strain unconstrained simple shear deformation in metals using a model two-dimensional cutting system and high-speed in situ imaging. The nature of the deformation mode is shown to be a function of the initial microstructure state of the metal and the deformation geometry. For annealed metals, which exhibit large ductility and strain hardening capacity, the commonly assumed laminar flow mode is inherently unstable. Instead, the imposed shear is accommodated by a highly rotational flow-sinuous flow-with vortex-like components and large-amplitude folding on the mesoscale. Sinuous flow is triggered by a plastic instability on the material surface ahead of the primary region of shear. On the other hand, when the material is extensively strain-hardened prior to shear, laminar flow again becomes unstable giving way to shear banding. The existence of these flow modes is established by stability analysis of laminar flow. The role of the initial microstructure state in determining the change in stability from laminar to sinuous / shear-banded flows in metals is elucidated. The implications for cutting, forming and wear processes for metals, and to surface plasticity phenomena such as mechanochemical Rehbinder effects are discussed.

The Critical Criterion on Runaway Shear Banding in Metallic Glasses

PubMed Central

Sun, B. A.; Yang, Y.; Wang, W. H.; Liu, C. T.

2016-01-01

The plastic flow of metallic glasses (MGs) in bulk is mediated by nanoscale shear bands, which is known to proceed in a stick-slip manner until reaching a transition state causing catastrophic failures. Such a slip-to-failure transition controls the plasticity of MGs and resembles many important phenomena in natural science and engineering, such as friction, lubrication and earthquake, therefore has attracted tremendous research interest over past decades. However, despite the fundamental and practical importance, the physical origin of this slip-to-failure transition is still poorly understood. By tracking the behavior of a single shear band, here we discover that the final fracture of various MGs during compression is triggered as the velocity of the dominant shear band rises to a critical value, the magnitude of which is independent of alloy composition, sample size, strain rate and testing frame stiffness. The critical shear band velocity is rationalized with the continuum theory of liquid instability, physically originating from a shear-induced cavitation process inside the shear band. Our current finding sheds a quantitative insight into deformation and fracture in disordered solids and, more importantly, is useful to the design of plastic/tough MG-based materials and structures. PMID:26893196

Stochastic dislocation kinetics and fractal structures in deforming metals probed by acoustic emission and surface topography measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vinogradov, A.; Laboratory of Hybrid Nanostructured Materials, NITU MISiS, Moscow 119490; Yasnikov, I. S.

2014-06-21

We demonstrate that the fractal dimension (FD) of the dislocation population in a deforming material is an important quantitative characteristic of the evolution of the dislocation structure. Thus, we show that peaking of FD signifies a nearing loss of uniformity of plastic flow and the onset of strain localization. Two techniques were employed to determine FD: (i) inspection of surface morphology of the deforming crystal by white light interferometry and (ii) monitoring of acoustic emission (AE) during uniaxial tensile deformation. A connection between the AE characteristics and the fractal dimension determined from surface topography measurements was established. As a commonmore » platform for the two methods, the dislocation density evolution in the bulk was used. The relations found made it possible to identify the occurrence of a peak in the median frequency of AE as a harbinger of plastic instability leading to necking. It is suggested that access to the fractal dimension provided by AE measurements and by surface topography analysis makes these techniques important tools for monitoring the evolution of the dislocation structure during plastic deformation—both as stand-alone methods and especially when used in tandem.« less

Investigation of crystalline structure of plasticized poly (lactic acid)/Banana nanofibers composites

NASA Astrophysics Data System (ADS)

Farid, T.; Herrera, V. N.; Kristiina, O.

2018-05-01

Polylactic acid (PLA) is a promising biodegradable candidate to replace synthetic commodity plastics in many applications. However, this polymer shows high brittleness, slow rate and lower degree of crystallization. The addition of plasticizing agents can enhance the toughness, but its effects on the crystallization behavior remain inconclusive. Therefore, this research is aiming to cast light on this area. Using differential scanning calorimetry (DSC) at a 2°C/min cooling rate, extruded neat PLA samples showed lower degree of crystallinity and thermal stability. This material shows cold crystallization upon heating and does recrystallize prior melting. These results indicate a clear instability in the crystalline state are confirmed by the crystallographic results by the X-ray diffractions (XRD) pattern and atomic force microscopic imagery. The addition of around 20 wt% of glycerol triacetate (GTA) with 1wt% of banana nanofibers (BNF) almost doubled the crystallinity. This modification is believed to occur through a dilution mechanism in order to increase crystallization rate yielding a more stable crystalline structure as shown by the XRD. However, the dynamic mechanical thermal analysis (DMTA) showed a 30 to 50% reduction in the room temperature storage modulus (stiffness) is in plasticized samples when compared to neat 100% PLA. Although these results shows the possibility to enhance the crystallization through a combination of plasticizing and nanoreinforcing effects, further studies is still needed to optimize the material formulation in order to find the best ratios to secure both a good crystallization and mechanical properties. This will definitively result in a new material that can be used for current and futuristic applications.

Finite-temperature mechanical instability in disordered lattices.

PubMed

Zhang, Leyou; Mao, Xiaoming

2016-02-01

Mechanical instability takes different forms in various ordered and disordered systems and little is known about how thermal fluctuations affect different classes of mechanical instabilities. We develop an analytic theory involving renormalization of rigidity and coherent potential approximation that can be used to understand finite-temperature mechanical stabilities in various disordered systems. We use this theory to study two disordered lattices: a randomly diluted triangular lattice and a randomly braced square lattice. These two lattices belong to two different universality classes as they approach mechanical instability at T=0. We show that thermal fluctuations stabilize both lattices. In particular, the triangular lattice displays a critical regime in which the shear modulus scales as G∼T(1/2), whereas the square lattice shows G∼T(2/3). We discuss generic scaling laws for finite-T mechanical instabilities and relate them to experimental systems.

Tibial Tubercle Osteotomies: a Review of a Treatment for Recurrent Patellar Instability.

PubMed

Grimm, Nathan L; Lazarides, Alexander L; Amendola, Annunziato

2018-06-01

The goal of this review is to provide an overview of current surgical treatment options for tibial tubercle osteotomies as a treatment for recurrent patellofemoral instability. As such we sought to provide the reader with the most current answers to why treatment practices have changed and how this has affected the outcome of surgical treatment for patellar instability. As our understanding of patellofemoral biomechanics have grown, appropriate surgical and non-surgical treatment options have followed suit to address these findings. A clear understanding of the pathomechanics causing the patient's patellar instability is germane to choosing the most appropriate surgical intervention to address this instability. Likewise, understanding the goal of the intervention chosen-e.g., unloading, realignment-is paramount. These surgical techniques may be technically challenging and surgical specialists with experience in these techniques are recommended for optimal outcomes.

Kelvin-Helmholtz instability of the Dirac fluid of charge carriers on graphene

NASA Astrophysics Data System (ADS)

Coelho, Rodrigo C. V.; Mendoza, Miller; Doria, Mauro M.; Herrmann, Hans J.

2017-11-01

We provide numerical evidence that a Kelvin-Helmholtz instability occurs in the Dirac fluid of electrons in graphene and can be detected in current experiments. This instability appears for electrons in the viscous regime passing though a micrometer-scale obstacle and affects measurements on the time scale of nanoseconds. A possible realization with a needle-shaped obstacle is proposed to produce and detect this instability by measuring the electric potential difference between contact points located before and after the obstacle. We also show that, for our setup, the Kelvin-Helmholtz instability leads to the formation of whirlpools similar to the ones reported in Bandurin et al. [Science 351, 1055 (2016), 10.1126/science.aad0201]. To perform the simulations, we develop a lattice Boltzmann method able to recover the full dissipation in a fluid of massless particles.

The Spinal Instability Neoplastic Score: Impact on Oncologic Decision-Making.

PubMed

Versteeg, Anne L; Verlaan, Jorrit-Jan; Sahgal, Arjun; Mendel, Ehud; Quraishi, Nasir A; Fourney, Daryl R; Fisher, Charles G

2016-10-15

Systematic literature review. To address the following questions in a systematic literature review: 1. How is spinal neoplastic instability defined or classified in the literature before and after the introduction of the Spinal Instability Neoplastic Score (SINS)? 2. How has SINS affected daily clinical practice? 3. Can SINS be used as a prognostic tool? Spinal neoplastic-related instability was defined in 2010 and simultaneously SINS was introduced as a novel tool with criteria agreed upon by expert consensus to assess the degree of spinal stability. PubMed, Embase, and clinical trial databases were searched with the key words "spinal neoplasm," "spinal instability," "spinal instability neoplastic score," and synonyms. Studies describing spinal neoplastic-related instability were eligible for inclusion. Primary outcomes included studies describing and/or defining neoplastic-related instability, SINS, and studies using SINS as a prognostic factor. The search identified 1414 articles, of which 51 met the inclusion criteria. No precise definition or validated assessment tool was used specific to spinal neoplastic-related instability prior to the introduction of SINS. Since the publication of SINS in 2010, the vast majority of the literature regarding spinal instability has used SINS to assess or describe instability. Twelve studies specifically investigated the prognostic value of SINS in patients who underwent radiotherapy or surgery. No consensus could be determined regarding the definition, assessment, or reporting of neoplastic-related instability before introduction of SINS. Defining spinal neoplastic-related instability and the introduction of SINS have led to improved uniform reporting within the spinal neoplastic literature. Currently, the prognostic value of SINS is controversial. N/A.

Magnetostructural Transition Kinetics in Shocked Iron

DOE PAGES

Surh, Michael P.; Benedict, Lorin X.; Sadigh, Babak

2016-08-15

Here, a generalized Heisenberg model is implemented to study the effect of thermal magnetic disorder on kinetics of the Fe α–ε transition. The barrier to bulk martensitic displacement remains large in α-Fe shocked well past the phase line but is much reduced in the [001] α–ε boundary. The first result is consistent with observed overdriving to metastable α, while the second suggests structural instability, as implied by observation of a [001] shock transformation front without plastic relaxation. Reconciling both behaviors may require concurrent treatment of magnetic and structural order.

Hippocampal Spike-Timing Correlations Lead to Hexagonal Grid Fields

NASA Astrophysics Data System (ADS)

Monsalve-Mercado, Mauro M.; Leibold, Christian

2017-07-01

Space is represented in the mammalian brain by the activity of hippocampal place cells, as well as in their spike-timing correlations. Here, we propose a theory for how this temporal code is transformed to spatial firing rate patterns via spike-timing-dependent synaptic plasticity. The resulting dynamics of synaptic weights resembles well-known pattern formation models in which a lateral inhibition mechanism gives rise to a Turing instability. We identify parameter regimes in which hexagonal firing patterns develop as they have been found in medial entorhinal cortex.

Reconnection and Associated Flares in Global Relativistic Jets Containing Helical Magnetic Fields with PIC Simulations

NASA Astrophysics Data System (ADS)

Nishikawa, Ken-Ichi; Hartmann, Dieter; Mizuno, Yosuke; Niemiec, Jacek; Dutan, Ioana; Kobzar, Oleh; Gomez, Jose; Meli, Athina; POHL, Martin

2018-01-01

In the study of relativistic jets one of the key open questions is their interaction with theenvironment on the microscopic level. Here, we study the initial evolution of both electron–proton and electron–positron relativistic jets containing helical magnetic fields, focusing on their interaction with an ambient plasma. We have performed simulations of “global” jets containing helical magnetic fields in order to examine how helical magnetic fields affect kinetic instabilities such as the Weibel instability, the kinetic Kelvin-Helmholtz instability (kKHI) and the Mushroom instability (MI) using a larger jet radius. In our initial simulation study these kinetic instabilities are suppressed and new types of instabilities can grow. In the electron-proton jet simulation a recollimation-like instability occurs near the center of jet. In the electron-positron jet simulation mixed kinetic instabilities grow and the jet electrons are accelerated. The evolution of electron-ion jets will be investigated with different mass ratios. Simulations using much larger systems are required in order to thoroughly follow the evolution of global jets containing helical magnetic fields. We will investigate mechanisms of flares possibly due to reconnection.

Polychlorinated biphenyls and organochlorine pesticides in plastics ingested by seabirds.

PubMed

Colabuono, Fernanda Imperatrice; Taniguchi, Satie; Montone, Rosalinda Carmela

2010-04-01

The occurrence of plastic objects in the digestive tract was assessed in eight species of Procellariiformes collected in southern Brazil and the occurrence of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) in the ingested plastics pellets and plastic fragments was evaluated. PCBs were detected in plastic pellets (491 ng g(-1)) and plastic fragments (243-418 ng g(-1)). Among the OCPs, p,p'-DDE had the highest concentrations, ranging from 68.0 to 99.0 ng g(-1). The occurrence of organic pollutants in post-consumer plastics supports the fact that plastics are an important source carrying persistent organic pollutants in the marine environment. Although transfer through the food chain may be the main source of exposure to POPs to seabirds, plastics could be an additional source for the organisms which ingest them, like Procellariiformes which are the seabirds most affected by plastic pollution. (c) 2010 Elsevier Ltd. All rights reserved.

Conservation laws in baroclinic inertial-symmetric instabilities

NASA Astrophysics Data System (ADS)

Grisouard, Nicolas; Fox, Morgan B.; Nijjer, Japinder

2017-04-01

Submesoscale oceanic density fronts are structures in geostrophic and hydrostatic balance, but are more prone to instabilities than mesoscale flows. As a consequence, they are believed to play a large role in air-sea exchanges, near-surface turbulence and dissipation of kinetic energy of geostrophically and hydrostatically balanced flows. We will present two-dimensional (x, z) Boussinesq numerical experiments of submesoscale baroclinic fronts on the f-plane. Instabilities of the mixed inertial and symmetric types (the actual name varies across the literature) develop, with the absence of along-front variations prohibiting geostrophic baroclinic instabilities. Two new salient facts emerge. First, contrary to pure inertial and/or pure symmetric instability, the potential energy budget is affected, the mixed instability extracting significant available potential energy from the front and dissipating it locally. Second, in the submesoscale regime, the growth rate of this mixed instability is sufficiently large that significant radiation of near-inertial internal waves occurs. Although energetically small compared to e.g. local dissipation within the front, this process might be a significant source of near-inertial energy in the ocean.

Lizards fail to plastically adjust nesting behavior or thermal tolerance as needed to buffer populations from climate warming.

PubMed

Telemeco, Rory S; Fletcher, Brooke; Levy, Ofir; Riley, Angela; Rodriguez-Sanchez, Yesenia; Smith, Colton; Teague, Collin; Waters, Amanda; Angilletta, Michael J; Buckley, Lauren B

2017-03-01

Although observations suggest the potential for phenotypic plasticity to allow adaptive responses to climate change, few experiments have assessed that potential. Modeling suggests that Sceloporus tristichus lizards will need increased nest depth, shade cover, or embryonic thermal tolerance to avoid reproductive failure resulting from climate change. To test for such plasticity, we experimentally examined how maternal temperatures affect nesting behavior and embryonic thermal sensitivity. The temperature regime that females experienced while gravid did not affect nesting behavior, but warmer temperatures at the time of nesting reduced nest depth. Additionally, embryos from heat-stressed mothers displayed increased sensitivity to high-temperature exposure. Simulations suggest that critically low temperatures, rather than high temperatures, historically limit development of our study population. Thus, the plasticity needed to buffer this population has not been under selection. Plasticity will likely fail to compensate for ongoing climate change when such change results in novel stressors. © 2016 John Wiley & Sons Ltd.

Thermonuclear instabilities and plasma edge transport in tokamaks

NASA Astrophysics Data System (ADS)

Fulop, Tunde Maria

High-energy ions generated by fusion reactions in a burning fusion plasma may give rise to different types of wave instabilities. The present thesis investigates two types of such instabilities which recently have been observed in fusion experiments: the Toroidal Alfvén Eigenmode (TAE) instability and the magnetoacoustic cyclotron instability (MCI) which is predicted to give rise to ion cyclotron emission (ICE). The TAE instability may degrade the confinement of fusion-produced high energy alpha particles and adversely affect the possibilities of reaching ignition. The present work derives it generalized expression for the linear growth rate of the instability, by including the effects of finite orbit width and finite Larmor radius of energetic particles, as well as the effects of mode localization and the possible mode excitation by both passing and trapped energetic ions. ICE does not threaten the plasma performance, but it might be useful as a fast ion diagnostic. The ICE originates from the MCI involving fast magnetoacoustic waves driven unstable by toroidicity-affected cyclotron resonance with fast ions. In the present thesis a detailed numerical and analytical investigation of this instability is presented, that explains most of the experimental ICE features observed in JET and TFTR. Moreover, the radial and poloidal localization of the fast magnetoacoustic eigenmodes is investigated, including the effects of toroidicity, ellipticity, the presence of a subpopulation of high energy ions and various profiles of the bulk ion density. In a fusion reactor, the transport of the particles near the edge have a strong influence on the global confinement of the plasma. In the edge region, where neutral atoms and impurity ions are abundant and the temperature and density gradients are large, the assumptions of the standard neoclassical theory break down. In this thesis, we explore the effect of neutral particles on the ion flow shear in the edge region. Furthermore, the neoclassical transport theory in an impure, toroidally rotating plasma is extended to allow for steeper pressure and temperature gradients than are usually considered.

Research and Development of a New Waste Collection Bin to Facilitate Education in Plastic Recycling

ERIC Educational Resources Information Center

Chow, Cheuk-fai; So, Wing-Mui Winnie; Cheung, Tsz-Yan

2016-01-01

Plastic recycling has been an alternative method for solid waste management apart from landfill and incineration. However, recycling quality is affected when all plastics are discarded into a single recycling bin that increases cross contaminations and operation cost to the recycling industry. Following the engineering design process, a new…

Elliptical Instability of Rotating Von Karman Street

NASA Astrophysics Data System (ADS)

Stegner, A.; Pichon, T.; Beunier, M.

Clouds often reveal a meso-scale vortex shedding in the wake of mountainous islands. Unlike the classical bi-dimensional Von-Karman street, these observed vortex street are affected by the earth rot ation and vertical stratification. Theses effects could induce a selective destabilization of anticyclonic vortices. It is well known that inertial instability (also called centrifugal instability) induce a three- dimensional destabilization of anticyclonic structures when the absolute vorticity is larger than the local Coriolis parameter. However, we have shown, by the mean of laboratory experiments, that it is a different type of instability which is mainly responsible for asymmetric rotating Von-Karman street. A serie of experiments were performed to study the wake of a cylinder in a rotating fluid, at medium Reynolds number and order one Rossby number. We have shown that the vertical structure of unstable anticyclonic vortices is characteristic of an elliptical instability. Besides, unlike the inertial instability, the vertical unstable wavelength depends on the Rossby number.

[Shoulder instability].

PubMed

Sailer, J; Imhof, H

2004-06-01

Shoulder instability is a common clinical feature leading to recurrent pain and limited range of motion within the glenohumeral joint. Instability can be due a single traumatic event, general joint laxity or repeated episodes of microtrauma. Differentiation between traumatic and atraumatic forms of shoulder instability requires careful history and a systemic clinical examination. Shoulder laxity has to be differentiated from true instability followed by the clinical assessment of direction and degree of glenohumeral translation. Conventional radiography and CT are used for the diagnosis of bony lesions. MR imaging and MR arthrography help in the detection of soft tissue affection, especially of the glenoid labrum and the capsuloligamentous complex. The most common lesion involving the labrum is the anterior labral tear, associated with capsuloperiostal stripping (Bankart lesion). A number of variants of the Bankart lesion have been described, such as ALPSA, SLAP or HAGL lesions. The purpose of this review is to highlight different forms of shoulder instability and its associated radiological findings with a focus on MR imaging.

Fast Transverse Instability and Electron Cloud Measurements in Fermilab Recycler

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eldred, Jeffery; Adamson, Philip; Capista, David

2015-03-01

A new transverse instability is observed that may limit the proton intensity in the Fermilab Recycler. The instability is fast, leading to a beam-abort loss within two hundred turns. The instability primarily affects the first high-intensity batch from the Fermilab Booster in each Recycler cycle. This paper analyzes the dynamical features of the destabilized beam. The instability excites a horizontal betatron oscillation which couples into the vertical motion and also causes transverse emittance growth. This paper describes the feasibility of electron cloud as the mechanism for this instability and presents the first measurements of the electron cloud in the Fermilabmore » Recycler. Direct measurements of the electron cloud are made using a retarding field analyzer (RFA) newly installed in the Fermilab Recycler. Indirect measurements of the electron cloud are made by propagating a microwave carrier signal through the beampipe and analyzing the phase modulation of the signal. The maximum betatron amplitude growth and the maximum electron cloud signal occur during minimums of the bunch length oscillation.« less

Tumor-Specific Chromosome Mis-Segregation Controls Cancer Plasticity by Maintaining Tumor Heterogeneity

PubMed Central

Hu, Yuanjie; Ru, Ning; Xiao, Huasheng; Chaturbedi, Abhishek; Hoa, Neil T.; Tian, Xiao-Jun; Zhang, Hang; Ke, Chao; Yan, Fengrong; Nelson, Jodi; Li, Zhenzhi; Gramer, Robert; Yu, Liping; Siegel, Eric; Zhang, Xiaona; Jia, Zhenyu; Jadus, Martin R.; Limoli, Charles L.; Linskey, Mark E.; Xing, Jianhua; Zhou, Yi-Hong

2013-01-01

Aneuploidy with chromosome instability is a cancer hallmark. We studied chromosome 7 (Chr7) copy number variation (CNV) in gliomas and in primary cultures derived from them. We found tumor heterogeneity with cells having Chr7-CNV commonly occurs in gliomas, with a higher percentage of cells in high-grade gliomas carrying more than 2 copies of Chr7, as compared to low-grade gliomas. Interestingly, all Chr7-aneuploid cell types in the parental culture of established glioma cell lines reappeared in single-cell-derived subcultures. We then characterized the biology of three syngeneic glioma cultures dominated by different Chr7-aneuploid cell types. We found phenotypic divergence for cells following Chr7 mis-segregation, which benefited overall tumor growth in vitro and in vivo. Mathematical modeling suggested the involvement of chromosome instability and interactions among cell subpopulations in restoring the optimal equilibrium of tumor cell types. Both our experimental data and mathematical modeling demonstrated that the complexity of tumor heterogeneity could be enhanced by the existence of chromosomes with structural abnormality, in addition to their mis-segregations. Overall, our findings show, for the first time, the involvement of chromosome instability in maintaining tumor heterogeneity, which underlies the enhanced growth, persistence and treatment resistance of cancers. PMID:24282558

Propagation mode of Portevin-Le Chatelier plastic instabilities in an aluminium-magnesium alloy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeghloul, A.; Mliha-Touati, M.; Bakir, S.

1996-11-01

The Portevin-Le Chatelier (PLC) effect is characterized by the appearance of serrations in load (hard tensile machine for constant strain rate tests) or by steps (soft tensile machine for constant stress rate tests) or by steps (soft tensile machine for constant stress rate tests) on the stress-strain curves. It is now widely accepted that the PLC propagative instability stems from the dynamic interaction between diffusing solute atoms and mobile dislocations in the temperature and strain rate ranges where dynamic strain ageing (DSA) takes place. This competition results in a negative strain-rate sensitivity. However, in some alloys, like concentrated solid solutions,more » shearing of precipitates accompanied by their dissolution and subsequent reprecipitation during tensile test may also lead to a negative strain rate sensitivity. In view of the renewed theoretical interest in propagative instabilities, it is important that the experimental features of band propagation be well characterized. In this work the authors present experimental results that are obtained from the investigation of the PLC bands associated with discontinuous yielding. These results show that the band strain, the band velocity and the propagation mode of the bands depend on the stress rate when the test is carried out on a soft tensile machine.« less

Education and Instability: Avoiding the Policy-Practice Gap in an Emerging Field

ERIC Educational Resources Information Center

Karpinska, Z. E.; Yarrow, Rachel; Gough, L. M. A.

2007-01-01

The imperative to provide education for communities affected by man-made or natural disaster has been strongly articulated. Since the mid 1990s, a growing body of literature and research has emerged in the fledgling field of "education and instability"; however, there is still a pressing need for high-quality, applicable research. The…

The role of sleep in regulating structural plasticity and synaptic strength: Implications for memory and cognitive function.

PubMed

Raven, Frank; Van der Zee, Eddy A; Meerlo, Peter; Havekes, Robbert

2018-06-01

Dendritic spines are the major sites of synaptic transmission in the central nervous system. Alterations in the strength of synaptic connections directly affect the neuronal communication, which is crucial for brain function as well as the processing and storage of information. Sleep and sleep loss bidirectionally alter structural plasticity, by affecting spine numbers and morphology, which ultimately can affect the functional output of the brain in terms of alertness, cognition, and mood. Experimental data from studies in rodents suggest that sleep deprivation may impact structural plasticity in different ways. One of the current views, referred to as the synaptic homeostasis hypothesis, suggests that wake promotes synaptic potentiation whereas sleep facilitates synaptic downscaling. On the other hand, several studies have now shown that sleep deprivation can reduce spine density and attenuate synaptic efficacy in the hippocampus. These data are the basis for the view that sleep promotes hippocampal structural plasticity critical for memory formation. Altogether, the impact of sleep and sleep loss may vary between regions of the brain. A better understanding of the role that sleep plays in regulating structural plasticity may ultimately lead to novel therapeutic approaches for brain disorders that are accompanied by sleep disturbances and sleep loss. Copyright © 2017 Elsevier Ltd. All rights reserved.

Tensile elastic properties of 18:8 chromium-nickel steel as affected by plastic deformation

NASA Technical Reports Server (NTRS)

Mcadam, D J; Mebs, R W

1939-01-01

The relationship between stress and strain, and between stress and permanent set, for 18:8 alloy as affected by prior plastic deformation is discussed. Hysteresis and creep and their effects on the stress-strain and stress-set curves are also considered, as well as the influence of duration of the rest interval after cold work and the influence of plastic deformation on proof stresses, on the modulus of elasticity at zero stress, and on the curvature of the stress-strain line. A constant (c sub 1) is suggested to represent the variation of the modulus of elasticity with stress.

Experiment Evaluation of Bifurcation in Sands

NASA Technical Reports Server (NTRS)

Alshibi, Khalid A.; Sture, Stein

2000-01-01

The basic principles of bifurcation analysis have been established by several investigators, however several issues remain unresolved, specifically how do stress level, grain size distribution, and boundary conditions affect general bifurcation phenomena in pressure sensitive and dilatant materials. General geometrical and kinematics conditions for moving surfaces of discontinuity was derived and applied to problems of instability of solids. In 1962, the theoretical framework of bifurcation by studying the acceleration waves in elasto-plastic (J2) solids were presented. Bifurcation analysis for more specific forms of constitutive behavior was examined by studying localization in pressure-sensitive, dilatant materials, however, analyses were restricted to plane deformation states only. Bifurcation analyses were presented and applied to predict shear band formations in sand under plane strain condition. The properties of discontinuous bifurcation solutions for elastic-plastic solids under axisymmetric and plane strain loading conditions were studied. The study focused on theory, but also references and comparisons to experiments were made. The current paper includes a presentation of a summary of bifurcation analyses for biaxial and triaxial (axisymmetric) loading conditions. The Coulomb model is implemented using incremental piecewise scheme to predict the constitutive relations and shear band inclination angles. Then, a comprehensive evaluation of bifurcation phenomena is presented based on data from triaxial experiments performed under microgravity conditions aboard the Space Shuttle under very low effective confining pressure (0.05 to 1.30 kPa), in which very high peak friction angles (47 to 75 degrees) and dilatancy angles (30 to 31 degrees) were measured. The evaluation will be extended to include biaxial experiments performed on the same material under low (10 kPa) and moderate (100 kPa) confining pressures. A comparison between the behavior under biaxial and triaxial loading conditions will be presented, and related issues concerning influence of confining pressure will be discussed.

[Progress on metaplasticity and its role in learning and memory].

PubMed

Wang, Shao-Li; Lu, Wei

2016-08-25

Long-term potentiation (LTP) and long-term depression (LTD) are two major forms of synaptic plasticity that are widely considered as important cellular models of learning and memory. Metaplasticity is defined as the plasticity of synaptic plasticity and thus is an advanced form of plasticity. The history of synaptic activity can affect the subsequent synaptic plasticity induction. Therefore, it is important to study metaplasticity to explore new mechanisms underlying various brain functions including learning and memory. Since the concept of metaplasticity was proposed, it has aroused widespread concerns and attracted numerous researchers to dig more details on this topic. These new-found experimental phenomena and cellular mechanisms have established the basis of theoretical studies on metaplasticity. In recent years, researchers have found that metaplasticity can not only affect the synaptic plasticity, but also regulate the neural network to encode specific content and enhance the learning and memory. These findings have greatly enriched our knowledge on plasticity and opened a new route to study the mechanism of learning and memory. In this review, we discuss the recent progress on metaplasticity on following three aspects: (1) the molecular mechanisms of metaplasticity; (2) the role of metaplasticity in learning and memory; and (3) the outlook of future study on metaplasticity.

The simulation of shock- and impact-driven flows with Mie-Gruneisen equations of state

NASA Astrophysics Data System (ADS)

Ward, Geoffrey M.

An investigation of shock- and impact-driven flows with Mie-Gruneisen equation of state derived from a linear shock-particle speed Hugoniot relationship is presented. Cartesian mesh methods using structured adaptive refinement are applied to simulate several flows of interest in an Eulerian frame of reference. The flows central to the investigation include planar Richtmyer-Meshkov instability, the impact of a sphere with a plate, and an impact-driven Mach stem. First, for multicomponent shock-driven flows, a dimensionally unsplit, spatially high-order, hybrid, center-difference, limiter methodology is developed. Effective switching between center-difference and upwinding schemes is achieved by a set of robust tolerance and Lax-entropy-based criteria [49]. Oscillations that result from such a mixed stencil scheme are minimized by requiring that the upwinding method approaches the center-difference method in smooth regions. The solver is then applied to investigate planar Richtmyer-Meshkov instability in the context of an equation of state comparison. Comparisons of simulations with materials modeled by isotropic stress Mie-Gruneisen equations of state derived from a linear shock-particle speed Hugoniot relationship [36,52] to those of perfect gases are made with the intention of exposing the role of the equation of state. First, results for single- and triple-mode planar Richtmyer-Meshkov instability between mid-ocean ridge basalt (MORB) and molybdenum modeled by Mie-Gruneisen equations of state are presented for the case of a reflected shock. The single-mode case is explored for incident shock Mach numbers of 1.5 and 2.5. Additionally, examined is single-mode Richtmyer-Meshkov instability when a reflected expansion wave is present for incident Mach numbers of 1.5 and 2.5. Comparison to perfect gas solutions in such cases yields a higher degree of similarity in start-up time and growth rate oscillations. Vorticity distribution and corrugation centerline shortly after shock interaction is also examined. The formation of incipient weak shock waves in the heavy fluid driven by waves emanating from the perturbed transmitted shock is observed when an expansion wave is reflected. Next, the ghost fluid method [83] is explored for application to impact-driven flows with Mie-Gruneisen equations of state in a vacuum. Free surfaces are defined utilizing a level-set approach. The level-set is reinitialized to the signed distance function periodically by solution to a Hamilton-Jacobi differential equation in artificial time. Flux reconstruction along each Cartesian direction of the domain is performed by subdividing in a way that allows for robust treatment of grid-scale sized voids. Ghost cells in voided regions near the material-vacuum interface are determined from surface-normal Riemann problem solution. The method is then applied to several impact problems of interest. First, a one-dimensional impact problem is examined in Mie-Gruneisen aluminum with simple point erosion used to model separation by spallation under high tension. A similar three-dimensional axisymmetric simulation of two rods impacting is then performed without a model for spallation. Further results for three-dimensional axisymmetric simulation of a sphere hitting a plate are then presented. Finally, a brief investigation of the assumptions utilized in modeling solids as isotropic fluids is undertaken. An Eulerian solver approach to handling elastic and elastic-plastic solids is utilized for comparison to the simple fluid model assumption. First, in one dimension an impact problem is examined for elastic, elastic-plastic, and fluid equations of state for aluminum. The results demonstrate that in one dimension the fluid models the plastic shock structure of the flow well. Further investigation is made using a three-dimensional axisymmetric simulation of an impact problem involving a copper cylinder surrounded by aluminum. An aluminum slab impact drives a faster shock in the outer aluminum region yielding a Mach reflection in the copper. The results demonstrate similar plastic shock structures. Several differences are also notable that include a lack of roll-up instability at the material interface and slip-line emanating from the Mach stem's triple point. (Abstract shortened by UMI.)

Geometric flow control of shear bands by suppression of viscous sliding

PubMed Central

Viswanathan, Koushik; Mahato, Anirban; Sundaram, Narayan K.; M'Saoubi, Rachid; Trumble, Kevin P.; Chandrasekar, Srinivasan

2016-01-01

Shear banding is a plastic flow instability with highly undesirable consequences for metals processing. While band characteristics have been well studied, general methods to control shear bands are presently lacking. Here, we use high-speed imaging and micro-marker analysis of flow in cutting to reveal the common fundamental mechanism underlying shear banding in metals. The flow unfolds in two distinct phases: an initiation phase followed by a viscous sliding phase in which most of the straining occurs. We show that the second sliding phase is well described by a simple model of two identical fluids being sheared across their interface. The equivalent shear band viscosity computed by fitting the model to experimental displacement profiles is very close in value to typical liquid metal viscosities. The observation of similar displacement profiles across different metals shows that specific microstructure details do not affect the second phase. This also suggests that the principal role of the initiation phase is to generate a weak interface that is susceptible to localized deformation. Importantly, by constraining the sliding phase, we demonstrate a material-agnostic method—passive geometric flow control—that effects complete band suppression in systems which otherwise fail via shear banding. PMID:27616920

Geometric flow control of shear bands by suppression of viscous sliding

NASA Astrophysics Data System (ADS)

Sagapuram, Dinakar; Viswanathan, Koushik; Mahato, Anirban; Sundaram, Narayan K.; M'Saoubi, Rachid; Trumble, Kevin P.; Chandrasekar, Srinivasan

2016-08-01

Shear banding is a plastic flow instability with highly undesirable consequences for metals processing. While band characteristics have been well studied, general methods to control shear bands are presently lacking. Here, we use high-speed imaging and micro-marker analysis of flow in cutting to reveal the common fundamental mechanism underlying shear banding in metals. The flow unfolds in two distinct phases: an initiation phase followed by a viscous sliding phase in which most of the straining occurs. We show that the second sliding phase is well described by a simple model of two identical fluids being sheared across their interface. The equivalent shear band viscosity computed by fitting the model to experimental displacement profiles is very close in value to typical liquid metal viscosities. The observation of similar displacement profiles across different metals shows that specific microstructure details do not affect the second phase. This also suggests that the principal role of the initiation phase is to generate a weak interface that is susceptible to localized deformation. Importantly, by constraining the sliding phase, we demonstrate a material-agnostic method-passive geometric flow control-that effects complete band suppression in systems which otherwise fail via shear banding.

Chronic, long-term social stress can cause decreased microtubule protein network activity and dynamics in cerebral cortex of male Wistar rats.

PubMed

Eskandari Sedighi, Ghazaleh; Riazi, Gholam Hossein; Vaez Mahdavi, Mohammad Reza; Cheraghi, Tayebe; Atarod, Deyhim; Rafiei, Shahrbanoo

2015-03-01

Social stress is viewed as a factor in the etiology of a variety of psychopathologies such as depression and anxiety. Animal models of social stress are well developed and widely used in studying clinical and physiological effects of stress. Stress is known to significantly affect learning and memory, and this effect strongly depends on the type of stress, its intensity, and duration. It has been demonstrated that chronic and acute stress conditions can change neuronal plasticity, characterized by retraction of apical dendrites, reduction in axonogenesis, and decreased neurogenesis. Various behavioral studies have also confirmed a decrease in learning and memory upon exposure of animals to long-term chronic stress. On the other hand, the close relationship between microtubule (MT) protein network and neuroplasticity controlling system suggests the possibility of MT protein alterations in high stressful conditions. In this work, we have studied the kinetics, activity, and dynamicity changes of MT proteins in the cerebral cortex of male Wistar rats that were subjected to social instability for 35 and 100 days. Our results indicate that MT protein network dynamicity and polymerization ability is decreased under long-term (100 days) social stress conditions.

Simulating Thermal Cycling and Isothermal Deformation Response of Polycrystalline NiTi

NASA Technical Reports Server (NTRS)

Manchiraju, Sivom; Gaydosh, Darrell J.; Noebe, Ronald D.; Anderson, Peter M.

2011-01-01

A microstructure-based FEM model that couples crystal plasticity, crystallographic descriptions of the B2-B19' martensitic phase transformation, and anisotropic elasticity is used to simulate thermal cycling and isothermal deformation in polycrystalline NiTi (49.9at% Ni). The model inputs include anisotropic elastic properties, polycrystalline texture, DSC data, and a subset of isothermal deformation and load-biased thermal cycling data. A key experimental trend is captured.namely, the transformation strain during thermal cycling is predicted to reach a peak with increasing bias stress, due to the onset of plasticity at larger bias stress. Plasticity induces internal stress that affects both thermal cycling and isothermal deformation responses. Affected thermal cycling features include hysteretic width, two-way shape memory effect, and evolution of texture with increasing bias stress. Affected isothermal deformation features include increased hardening during loading and retained martensite after unloading. These trends are not captured by microstructural models that lack plasticity, nor are they all captured in a robust manner by phenomenological approaches. Despite this advance in microstructural modeling, quantitative differences exist, such as underprediction of open loop strain during thermal cycling.

Arc Deflection Length Affected by Transverse Rotating Magnetic Field with Lateral Gas

NASA Astrophysics Data System (ADS)

Shiino, Toru; Ishii, Yoko; Yamamoto, Shinji; Iwao, Toru; High Current Energy Laboratory (HiCEL) Team

2016-10-01

Gas metal arc welding using shielding gas is often used in the welding industry. However, the arc deflection affected by lateral gas is problem because of inappropriate heat transfer. Shielding gas is used in order to prevent the instability affected by the arc deflection. However, the shielding gas causes turbulence, then blowhole of weld defect occurs because the arc affected by the instability is contaminated by the air. Thus, the magnetic field is applied to the arc in order to stabilize the arc using low amount of shielding gas. The method of applying the transverse rotating magnetic field (RMF) to the arc is one of the methods to prevent the arc instability. The RMF drives the arc because of electromagnetic force. The driven arc is considered to be prevented to arc deflection of lateral gas because the arc is restrained by the magnetic field because of the driven arc. In addition, it is assume the RMF prevented to the arc deflection of lateral gas from the multiple directions. In this paper, the arc deflection length affected by the RMF with lateral gas was elucidated in order to know the effect of the RMF for arc stabilization. Specifically, the arc deflection length affected by the magnetic frequency and the magnetic flux density is measured by high speed video camera. As a result, the arc deflection length decreases with increasing magnetic frequency, and the arc deflection length increases with increasing the magnetic flux density.

Microstructure Instability of Candidate Fuel Cladding Alloys: Corrosion and Stress Corrosion Cracking Implications

NASA Astrophysics Data System (ADS)

Jiao, Yinan; Zheng, Wenyue; Guzonas, David; Kish, Joseph

2016-02-01

This paper addresses some of the overarching aspects of microstructure instability expected from both high temperature and radiation exposure that could affect the corrosion and stress corrosion cracking (SCC) resistance of the candidate austenitic Fe-Cr-Ni alloys being considered for the fuel cladding of the Canadian supercritical water-cooled reactor (SCWR) concept. An overview of the microstructure instability expected by both exposures is presented prior to turning the focus onto the implications of such instability on the corrosion and SCC resistance. Results from testing conducted using pre-treated (thermally-aged) Type 310S stainless steel to shed some light on this important issue are included to help identify the outstanding corrosion resistance assessment needs.

Genome instabilities arising from ribonucleotides in DNA.

PubMed

Klein, Hannah L

2017-08-01

Genomic DNA is transiently contaminated with ribonucleotide residues during the process of DNA replication through misincorporation by the replicative DNA polymerases α, δ and ε, and by the normal replication process on the lagging strand, which uses RNA primers. These ribonucleotides are efficiently removed during replication by RNase H enzymes and the lagging strand synthesis machinery. However, when ribonucleotides remain in DNA they can distort the DNA helix, affect machineries for DNA replication, transcription and repair, and can stimulate genomic instabilities which are manifest as increased mutation, recombination and chromosome alterations. The genomic instabilities associated with embedded ribonucleotides are considered here, along with a discussion of the origin of the lesions that stimulate particular classes of instabilities. Copyright © 2017 Elsevier B.V. All rights reserved.

Causes of genome instability: the effect of low dose chemical exposures in modern society.

PubMed

Langie, Sabine A S; Koppen, Gudrun; Desaulniers, Daniel; Al-Mulla, Fahd; Al-Temaimi, Rabeah; Amedei, Amedeo; Azqueta, Amaya; Bisson, William H; Brown, Dustin G; Brunborg, Gunnar; Charles, Amelia K; Chen, Tao; Colacci, Annamaria; Darroudi, Firouz; Forte, Stefano; Gonzalez, Laetitia; Hamid, Roslida A; Knudsen, Lisbeth E; Leyns, Luc; Lopez de Cerain Salsamendi, Adela; Memeo, Lorenzo; Mondello, Chiara; Mothersill, Carmel; Olsen, Ann-Karin; Pavanello, Sofia; Raju, Jayadev; Rojas, Emilio; Roy, Rabindra; Ryan, Elizabeth P; Ostrosky-Wegman, Patricia; Salem, Hosni K; Scovassi, A Ivana; Singh, Neetu; Vaccari, Monica; Van Schooten, Frederik J; Valverde, Mahara; Woodrick, Jordan; Zhang, Luoping; van Larebeke, Nik; Kirsch-Volders, Micheline; Collins, Andrew R

2015-06-01

Genome instability is a prerequisite for the development of cancer. It occurs when genome maintenance systems fail to safeguard the genome's integrity, whether as a consequence of inherited defects or induced via exposure to environmental agents (chemicals, biological agents and radiation). Thus, genome instability can be defined as an enhanced tendency for the genome to acquire mutations; ranging from changes to the nucleotide sequence to chromosomal gain, rearrangements or loss. This review raises the hypothesis that in addition to known human carcinogens, exposure to low dose of other chemicals present in our modern society could contribute to carcinogenesis by indirectly affecting genome stability. The selected chemicals with their mechanisms of action proposed to indirectly contribute to genome instability are: heavy metals (DNA repair, epigenetic modification, DNA damage signaling, telomere length), acrylamide (DNA repair, chromosome segregation), bisphenol A (epigenetic modification, DNA damage signaling, mitochondrial function, chromosome segregation), benomyl (chromosome segregation), quinones (epigenetic modification) and nano-sized particles (epigenetic pathways, mitochondrial function, chromosome segregation, telomere length). The purpose of this review is to describe the crucial aspects of genome instability, to outline the ways in which environmental chemicals can affect this cancer hallmark and to identify candidate chemicals for further study. The overall aim is to make scientists aware of the increasing need to unravel the underlying mechanisms via which chemicals at low doses can induce genome instability and thus promote carcinogenesis. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Opposite Roles for p38MAPK-Driven Responses and Reactive Oxygen Species in the Persistence and Resolution of Radiation-Induced Genomic Instability

PubMed Central

Werner, Erica; Wang, Huichen; Doetsch, Paul W.

2014-01-01

We report the functional and temporal relationship between cellular phenotypes such as oxidative stress, p38MAPK-dependent responses and genomic instability persisting in the progeny of cells exposed to sparsely ionizing low-Linear Energy Transfer (LET) radiation such as X-rays or high-charge and high-energy (HZE) particle high-LET radiation such as 56Fe ions. We found that exposure to low and high-LET radiation increased reactive oxygen species (ROS) levels as a threshold-like response induced independently of radiation quality and dose. This response was sustained for two weeks, which is the period of time when genomic instability is evidenced by increased micronucleus formation frequency and DNA damage associated foci. Indicators for another persisting response sharing phenotypes with stress-induced senescence, including beta galactosidase induction, increased nuclear size, p38MAPK activation and IL-8 production, were induced in the absence of cell proliferation arrest during the first, but not the second week following exposure to high-LET radiation. This response was driven by a p38MAPK-dependent mechanism and was affected by radiation quality and dose. This stress response and elevation of ROS affected genomic instability by distinct pathways. Through interference with p38MAPK activity, we show that radiation-induced stress phenotypes promote genomic instability. In contrast, exposure to physiologically relevant doses of hydrogen peroxide or increasing endogenous ROS levels with a catalase inhibitor reduced the level of genomic instability. Our results implicate persistently elevated ROS following exposure to radiation as a factor contributing to genome stabilization. PMID:25271419

Domains of pulsational instability of low-frequency modes in rotating upper main sequence stars

NASA Astrophysics Data System (ADS)

Szewczuk, Wojciech; Daszyńska-Daszkiewicz, Jadwiga

2017-07-01

We determine instability domains on the Hertzsprung-Russell diagram for rotating main sequence stars with masses of 2-20 M⊙. The effects of the Coriolis force are treated wihin the traditional approximation. High-order g modes with harmonic degrees ℓ up to 4 and mixed gravity-Rossby modes with |m| up to 4 are considered. We include the effects of rotation in wider instability strips for a given ℓ compared to the non-rotating case and in an extension of the pulsational instability to hotter and more massive models. We present results for a fixed value of the initial rotation velocity as well as for a fixed ratio of the angular rotation frequency to its critical value. Moreover, we check how the initial hydrogen abundance, metallicity, overshooting from the convective core and opacity affect the pulsational instability domains. The effect of rotation on the period spacing is also discussed.

Social instability and immunity in rhesus monkeys: the role of the sympathetic nervous system.

PubMed

Capitanio, John P; Cole, Steven W

2015-05-26

Social instability can adversely affect endocrine, immune and health outcomes, and recent evidence suggests that the sympathetic nervous system (SNS) might mediate these effects. We conducted two studies with adult male rhesus monkeys (Macaca mulatta) to understand how social conditions affect measures of SNS activity and immune function. In Experiment 1, animals were socialized in stable social conditions, then were switched to unstable (stressful) social conditions, then were returned to stable conditions. Analysis revealed quadratic effects for measures of behaviour, urinary metabolites of epinephrine and norepinephrine, and expression of immune response genes: as expected, social instability adversely impacted most measures, and the effects remediated upon re-imposition of stable conditions. Cortisol levels were unaffected. In Experiment 2, we used the sympathomimetic drug methamphetamine to challenge the SNS; animals also underwent socialization in stable or unstable groups. Surprisingly, while methamphetamine elevated plasma catecholamines, responses in lymph nodes tracked the social, and not the drug, condition: social instability upregulated the density of SNS fibres in lymph nodes and downregulated Type I interferon gene expression. Together, these results indicate that the SNS is extremely sensitive to social conditions; full understanding of the adverse effects of social instability on health should therefore incorporate measures of this health-relevant system. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Plastic Surgeons’ Perceptions of the Affordable Care Act: Results of a National Survey

PubMed Central

Israel, Jacqueline S.; Chen, Jenny T.; Rao, Venkat K.

2015-01-01

Background: The Affordable Care Act (ACA) aims to expand coverage to the uninsured, improve quality, and contain costs. The goal of this study was to ascertain how plastic surgeons perceive the ACA. Methods: An electronic questionnaire was e-mailed to members of the American Society of Plastic Surgeons between May and June 2014. The survey was anonymous and voluntary and included questions to assess understanding and opinions of the ACA. Results: The survey was sent to 3070 members of the American Society of Plastic Surgeons, and the response rate was 17%. Sixty-eight percent agree or strongly agree that they understand the basic concepts of the ACA. The majority of respondents disagree (38% strongly disagree, 31% disagree) with the notion that the ACA will positively affect their practice, and 51% agree with the statement, “I do not support the ACA, and I believe it did too much.” Two thirds (66%) believe that the ACA deserves a grade of D or F. When answers were analyzed across demographics, 42% of respondents with “Academic” practice background identify with the statement, “I support the ACA but I think it needs more work,” compared to 15% of those who selected “Solo Practice” (p <0.001). Conclusions: The ACA will affect all specialties, including plastic surgery. The results of this survey suggest that many plastic surgeons believe that they have a baseline understanding of current health-care reform. The majority of surveyed surgeons do not support the Act. It is imperative that plastic surgeons possess the knowledge of the ACA; its changes, both current and impending, will likely affect patient mix, coverage of procedures, and reimbursement. PMID:25674374

Shear localization in three-dimensional amorphous solids.

PubMed

Dasgupta, Ratul; Gendelman, Oleg; Mishra, Pankaj; Procaccia, Itamar; Shor, Carmel A B Z

2013-09-01

In this paper we extend the recent theory of shear localization in two-dimensional (2D) amorphous solids to three dimensions. In two dimensions the fundamental instability of shear localization is related to the appearance of a line of displacement quadrupoles that makes an angle of 45^{∘} with the principal stress axis. In three dimensions the fundamental plastic instability is also explained by the formation of a lattice of anisotropic elastic inclusions. In the case of pure external shear stress, we demonstrate that this is a 2D triangular lattice of similar elementary events. It is shown that this lattice is arranged on a plane that, similarly to the 2D case, makes an angle of 45^{∘} with the principal stress axis. This solution is energetically favorable only if the external strain exceeds a yield-strain value that is determined by the strain parameters of the elementary events and the Poisson ratio. The predictions of the theory are compared to numerical simulations and very good agreement is observed.

Material instabilities and their role for the initiation of boudinage and folding structures

NASA Astrophysics Data System (ADS)

Veveakis, Manolis; Peters, Max; Poulet, Thomas; Karrech, Ali; Herwegh, Marco; Regenauer-Lieb, Klaus

2015-04-01

Localized phenomena, such as pinch-and-swell boudinage or localized folds, are usually interpreted to arise from viscosity contrasts. These are caused by structural heterogeneities, such as geometric or material imperfections. An alternative possibility for strain localization exists in material science, where dynamic localization emerges out of a steady state for a given critical set of material parameters and loading rates (Montési and Zuber, 2002). In our contribution, we will investigate the conditions under which this type of instabilities triggers localized deformation. Moreover, we discuss whether geological materials necessarily require structural heterogeneities, such as weak seeds, in order to generate aforementioned localized structures. We set up a random distribution of grain sizes in a layer embedded in a matrix with a diffusion creep rheology. Deformation within the layer is accommodated by dislocation and diffusion creep as end member deformation mechanism. The grain size evolution follows the paleowattmeter scaling relationship for calcite creep (Austin and Evans, 2007), which is controlled by thermo-mechanical feedbacks (Herwegh et al., 2014). During the first strain increments in the numerical simulation, the layer establishes a viscous steady state, which is the systems' response to optimize energy following the paleowattmeter (Herwegh et al., 2014). With further loading, localization interestingly arises out of a homogeneous state. We will demonstrate the robustness of this numerical solution by identifying the natural mode shapes and frequencies of the simulated structure and material parameters, including geometric imperfections (Rudnicki and Rice, 1975). This technique aims at the determination of the spatial manifestation of the instability pattern (Peters et al., in review). The eigenvalues are thought to represent the nodal points, where the onset of (visco)-elasto-plastic localization can initiate in the structure (Rudnicki and Rice, 1975). The eigenmodes appear as sinusoidal vibrations with geometry- and material parameter-specific natural modal frequencies and shapes. In a next step, the eigenmodes are perturbed and superposed to the initial conditions. We observe that this pattern of perturbations guides the ultimate material bifurcation. Boudinage and folding can therefore be seen as either a pure geometric problem or a fundamental material bifurcation, which evolves out of homogeneous state. The latter class offers the great possibility to extract fundamental material parameters out of localized structures directly from field observations. REFERENCES Herwegh, M., Poulet, T., Karrech, A. and Regenauer-Lieb, K. (2014). From transient to steady state deformation and grain size: A thermodynamic approach using elasto-visco-plastic numerical modeling. Journal of Geophysical Research, 119. Montési, L.G.J. and Zuber, M.T. (2002). A unified description of localization for application to large-scale tectonics. Journal of Geophysical Research, 107. Peters, M., Veveakis, M., Poulet, T., Karrech, A., Herwegh, M. and Regenauer-Lieb Klaus (in review). Boudinage as a material instability of elasto-visco-plastic rocks. Submitted to Journal of Structural Geology. Rudnicki, J. W., Rice, J. R. (1975). Conditions for the localization of deformation in pressure-sensitive dilatant materials. Journal of Mechanics and Physics of Solids, 23.

Shoulder instability in professional football players.

PubMed

Leclere, Lance E; Asnis, Peter D; Griffith, Matthew H; Granito, David; Berkson, Eric M; Gill, Thomas J

2013-09-01

Shoulder instability is a common problem in American football players entering the National Football League (NFL). Treatment options include nonoperative and surgical stabilization. This study evaluated how the method of treatment of pre-NFL shoulder instability affects the rate of recurrence and the time elapsed until recurrence in players on 1 NFL team. Retrospective cohort. Medical records from 1980 to 2008 for 1 NFL team were reviewed. There were 328 players included in the study who started their career on the team and remained on the team for at least 2 years (mean, 3.9 years; range, 2-14 years). The history of instability prior to entering the NFL and the method of treatment were collected. Data on the occurrence of instability while in the NFL were recorded to determine the rate and timing of recurrence. Thirty-one players (9.5%) had a history of instability prior to entering the NFL. Of the 297 players with no history of instability, 39 (13.1%) had a primary event at a mean of 18.4 ± 22.2 months (range, 0-102 months) after joining the team. In the group of players with prior instability treated with surgical stabilization, there was no statistical difference in the rate of recurrence (10.5%) or the timing to the instability episode (mean, 26 months) compared with players with no history of instability. Twelve players had shoulder instability treated nonoperatively prior to the NFL. Five of these players (41.7%) had recurrent instability at a mean of 4.4 ± 7.0 months (range, 0-16 months). The patients treated nonoperatively had a significantly higher rate of recurrence (P = 0.02) and an earlier time of recurrence (P = 0.04). The rate of contralateral instability was 25.8%, occurring at a mean of 8.6 months. Recurrent shoulder instability is more common in NFL players with a history of nonoperative treatment. Surgical stabilization appears to restore the rate and timing of instability to that of players with no prior history of instability.

40 CFR 60.720 - Applicability and designation of affected facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... in which plastic parts for use in the manufacture of business machines receive prime coats, color... Performance for Industrial Surface Coating: Surface Coating of Plastic Parts for Business Machines § 60.720...

Apparent plasticity in functional traits determining competitive ability and spatial distribution: a case from desert.

PubMed

Xie, Jiang-Bo; Xu, Gui-Qing; Jenerette, G Darrel; Bai, Yong-fei; Wang, Zhong-Yuan; Li, Yan

2015-07-20

Species competitive abilities and their distributions are closely related to functional traits such as biomass allocation patterns. When we consider how nutrient supply affects competitive abilities, quantifying the apparent and true plasticity in functional traits is important because the allometric relationships among traits are universal in plants. We propose to integrate the notion of allometry and the classical reaction norm into a composite theoretical framework that quantifies the apparent and true plasticity. Combining the framework with a meta-analysis, a series of field surveys and a competition experiment, we aimed to determine the causes of the dune/interdune distribution patterns of two Haloxylon species in the Gurbantonggut Desert. We found that (1) the biomass allocation patterns of both Haloxylon species in responses to environmental conditions were apparent rather than true plasticity and (2) the allometric allocation patterns affected the plants' competition for soil nutrient supply. A key implication of our results is that the apparent plasticity in functional traits of plants determines their response to environmental change. Without identifying the apparent and true plasticity, we would substantially overestimate the magnitude, duration and even the direction of plant responses in functional traits to climate change.

Apparent plasticity in functional traits determining competitive ability and spatial distribution: a case from desert

PubMed Central

Xie, Jiang-Bo; Xu, Gui-Qing; Jenerette, G. Darrel; Bai, Yong-fei; Wang, Zhong-Yuan; Li, Yan

2015-01-01

Species competitive abilities and their distributions are closely related to functional traits such as biomass allocation patterns. When we consider how nutrient supply affects competitive abilities, quantifying the apparent and true plasticity in functional traits is important because the allometric relationships among traits are universal in plants. We propose to integrate the notion of allometry and the classical reaction norm into a composite theoretical framework that quantifies the apparent and true plasticity. Combining the framework with a meta-analysis, a series of field surveys and a competition experiment, we aimed to determine the causes of the dune/interdune distribution patterns of two Haloxylon species in the Gurbantonggut Desert. We found that (1) the biomass allocation patterns of both Haloxylon species in responses to environmental conditions were apparent rather than true plasticity and (2) the allometric allocation patterns affected the plants’ competition for soil nutrient supply. A key implication of our results is that the apparent plasticity in functional traits of plants determines their response to environmental change. Without identifying the apparent and true plasticity, we would substantially overestimate the magnitude, duration and even the direction of plant responses in functional traits to climate change. PMID:26190745

Diet and cognition: interplay between cell metabolism and neuronal plasticity

PubMed Central

Gomez-Pinilla, Fernando; Tyagi, Ethika

2014-01-01

Purpose of Study To discuss studies in humans and animals revealing the ability of foods to benefit the brain: new information with regards to mechanisms of action and the treatment of neurological and psychiatric disorders. Recent Findings Dietary factors exert their effects on the brain by affecting molecular events related to the management of energy metabolism and synaptic plasticity. Energy metabolism influences neuronal function, neuronal signaling, and synaptic plasticity, ultimately affecting mental health. Epigenetic regulation of neuronal plasticity appears as an important mechanism by which foods can prolong their effects on long term neuronal plasticity. Summary The prime focus of the discussion is to emphasize the role of cell metabolism as a mediator for the action of foods on the brain. Oxidative stress promotes damage to phospholipids present in the plasma membrane such as the omega-3 fatty acid DHA, disrupting neuronal signaling. Thus, dietary DHA seems crucial for supporting plasma membrane function, interneuronal signaling, and cognition. The dual action of brain-derived neurotrophic factor (BDNF) in neuronal metabolism and synaptic plasticity is crucial for activating signaling cascades under the action of diet and other environmental factors, using mechanisms of epigenetic regulation. PMID:24071781

Ingestion of Plastic Microfibers by the Crab Carcinus maenas and Its Effect on Food Consumption and Energy Balance.

PubMed

Watts, Andrew J R; Urbina, Mauricio A; Corr, Shauna; Lewis, Ceri; Galloway, Tamara S

2015-12-15

Microscopic plastic fragments (<5 mm) are a worldwide conservation issue, polluting both coastal and marine environments. Fibers are the most prominent plastic type reported in the guts of marine organisms, but their effects once ingested are unknown. This study investigated the fate of polypropylene rope microfibers (1-5 mm in length) ingested by the crab Carcinus maenas and the consequences for the crab's energy budget. In chronic 4 week feeding studies, crabs that ingested food containing microfibers (0.3-1.0% plastic by weight) showed reduced food consumption (from 0.33 to 0.03 g d(-1)) and a significant reduction in energy available for growth (scope for growth) from 0.59 to -0.31 kJ crab d(-1) in crabs fed with 1% plastic. The polypropylene microfibers were physically altered by their passage through the foregut and were excreted with a smaller overall size and length and amalgamated into distinctive balls. These results support of the emerging paradigm that a key biological impact of microplastic ingestion is a reduction in energy budgets for the affected marine biota. We also provide novel evidence of the biotransformations that can affect the plastics themselves following ingestion and excretion.

Cognitive and affective trait and state factors influencing the long-term symptom course in remitted depressed patients.

PubMed

Timm, Christina; Ubl, Bettina; Zamoscik, Vera; Ebner-Priemer, Ulrich; Reinhard, Iris; Huffziger, Silke; Kirsch, Peter; Kuehner, Christine

2017-01-01

Major depressive disorder (MDD) is characterized by a high risk for relapses and chronic developments. Clinical characteristics such as residual symptoms have been shown to negatively affect the long-term course of MDD. However, it is unclear so far how trait repetitive negative thinking (RNT) as well as cognitive and affective momentary states, the latter experienced during daily-life, affect the long-term course of MDD. We followed up 57 remitted depressed (rMDD) individuals six (T2) and 36 (T3) months after baseline. Clinical outcomes were time to relapse, time spent with significant symptoms as a marker of chronicity, and levels of depressive symptoms at T2 and T3. Predictors assessed at baseline included residual symptoms and trait RNT. Furthermore, momentary daily life affect and momentary rumination, and their variation over the day were assessed at baseline using ambulatory assessment (AA). In multiple models, residual symptoms and instability of daily-life affect at baseline independently predicted a faster time to relapse, while chronicity was significantly predicted by trait RNT. Multilevel models revealed that depressive symptom levels during follow-up were predicted by baseline residual symptom levels and by instability of daily-life rumination. Both instability features were linked to a higher number of anamnestic MDD episodes. Our findings indicate that trait RNT, but also affective and cognitive processes during daily life impact the longer-term course of MDD. Future longitudinal research on the role of respective AA-phenotypes as potential transdiagnostic course-modifiers is warranted.

Early alcohol exposure impairs ocular dominance plasticity throughout the critical period.

PubMed

Medina, Alexandre E; Ramoa, Ary S

2005-06-09

Animal models of fetal alcohol syndrome (FAS) have revealed an impairment of sensory neocortex plasticity. Here, we examine whether early alcohol exposure leads to a permanent impairment of ocular dominance plasticity (OD) or to an alteration in the timing of the critical period. Ferrets were exposed to alcohol during a brief period of development prior to eye opening and effects of monocular deprivation examined during early, mid and late critical period. Single-unit electrophysiology revealed markedly reduced OD plasticity at every age examined. This finding provides evidence that early alcohol exposure does not affect the timing or duration of the critical period of OD plasticity and suggests an enduring impairment of neural plasticity in FAS.

The pollution of the marine environment by plastic debris: a review.

PubMed

Derraik, José G B

2002-09-01

The deleterious effects of plastic debris on the marine environment were reviewed by bringing together most of the literature published so far on the topic. A large number of marine species is known to be harmed and/or killed by plastic debris, which could jeopardize their survival, especially since many are already endangered by other forms of anthropogenic activities. Marine animals are mostly affected through entanglement in and ingestion of plastic litter. Other less known threats include the use of plastic debris by "invader" species and the absorption of polychlorinated biphenyls from ingested plastics. Less conspicuous forms, such as plastic pellets and "scrubbers" are also hazardous. To address the problem of plastic debris in the oceans is a difficult task, and a variety of approaches are urgently required. Some of the ways to mitigate the problem are discussed.

A comprehensive constitutive law for waxy crude oil: a thixotropic yield stress fluid.

PubMed

Dimitriou, Christopher J; McKinley, Gareth H

2014-09-21

Guided by a series of discriminating rheometric tests, we develop a new constitutive model that can quantitatively predict the key rheological features of waxy crude oils. We first develop a series of model crude oils, which are characterized by a complex thixotropic and yielding behavior that strongly depends on the shear history of the sample. We then outline the development of an appropriate preparation protocol for carrying out rheological measurements, to ensure consistent and reproducible initial conditions. We use RheoPIV measurements of the local kinematics within the fluid under imposed deformations in order to validate the selection of a particular protocol. Velocimetric measurements are also used to document the presence of material instabilities within the model crude oil under conditions of imposed steady shearing. These instabilities are a result of the underlying non-monotonic steady flow curve of the material. Three distinct deformation histories are then used to probe the material's constitutive response. These deformations are steady shear, transient response to startup of steady shear with different aging times, and large amplitude oscillatory shear (LAOS). The material response to these three different flows is used to motivate the development of an appropriate constitutive model. This model (termed the IKH model) is based on a framework adopted from plasticity theory and implements an additive strain decomposition into characteristic reversible (elastic) and irreversible (plastic) contributions, coupled with the physical processes of isotropic and kinematic hardening. Comparisons of experimental to simulated response for all three flows show good quantitative agreement, validating the chosen approach for developing constitutive models for this class of materials.

Self-reported knee joint instability is related to passive mechanical stiffness in medial knee osteoarthritis.

PubMed

Creaby, Mark W; Wrigley, Tim V; Lim, Boon-Whatt; Hinman, Rana S; Bryant, Adam L; Bennell, Kim L

2013-11-20

Self-reported knee joint instability compromises function in individuals with medial knee osteoarthritis and may be related to impaired joint mechanics. The purpose of this study was to evaluate the relationship between self-reported instability and the passive varus-valgus mechanical behaviour of the medial osteoarthritis knee. Passive varus-valgus angular laxity and stiffness were assessed using a modified isokinetic dynamometer in 73 participants with medial tibiofemoral osteoarthritis. All participants self-reported the absence or presence of knee instability symptoms and the degree to which instability affected daily activity on a 6-point likert scale. Forward linear regression modelling identified a significant inverse relationship between passive mid-range knee stiffness and symptoms of knee instability (r = 0.27; P < 0.05): reduced stiffness was indicative of more severe instability symptoms. Angular laxity and end-range stiffness were not related to instability symptoms (P > 0.05). Conceivably, a stiffer passive system may contribute toward greater joint stability during functional activities. Importantly however, net joint stiffness is influenced by both active and passive stiffness, and thus the active neuromuscular system may compensate for reduced passive stiffness in order to maintain joint stability. Future work is merited to examine the role of active stiffness in symptomatic joint stability.

Self-reported knee joint instability is related to passive mechanical stiffness in medial knee osteoarthritis

PubMed Central

2013-01-01

Background Self-reported knee joint instability compromises function in individuals with medial knee osteoarthritis and may be related to impaired joint mechanics. The purpose of this study was to evaluate the relationship between self-reported instability and the passive varus-valgus mechanical behaviour of the medial osteoarthritis knee. Methods Passive varus-valgus angular laxity and stiffness were assessed using a modified isokinetic dynamometer in 73 participants with medial tibiofemoral osteoarthritis. All participants self-reported the absence or presence of knee instability symptoms and the degree to which instability affected daily activity on a 6-point likert scale. Results Forward linear regression modelling identified a significant inverse relationship between passive mid-range knee stiffness and symptoms of knee instability (r = 0.27; P < 0.05): reduced stiffness was indicative of more severe instability symptoms. Angular laxity and end-range stiffness were not related to instability symptoms (P > 0.05). Conclusions Conceivably, a stiffer passive system may contribute toward greater joint stability during functional activities. Importantly however, net joint stiffness is influenced by both active and passive stiffness, and thus the active neuromuscular system may compensate for reduced passive stiffness in order to maintain joint stability. Future work is merited to examine the role of active stiffness in symptomatic joint stability. PMID:24252592

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

PubMed Central

Ferguson, Lynnette R.; Chen, Helen; Collins, Andrew R.; Connell, Marisa; Damia, Giovanna; Dasgupta, Santanu; Malhotra, Meenakshi; Meeker, Alan K.; Amedei, Amedeo; Amin, Amr; Ashraf, S. Salman; Aquilano, Katia; Azmi, Asfar S.; Bhakta, Dipita; Bilsland, Alan; Boosani, Chandra S.; Chen, Sophie; Ciriolo, Maria Rosa; Fujii, Hiromasa; Guha, Gunjan; Halicka, Dorota; Helferich, William G.; Keith, W. Nicol; Mohammed, Sulma I.; Niccolai, Elena; Yang, Xujuan; Honoki, Kanya; Parslow, Virginia R.; Prakash, Satya; Rezazadeh, Sarallah; Shackelford, Rodney E.; Sidransky, David; Tran, Phuoc T.; Yang, Eddy S.; Maxwell, Christopher A.

2015-01-01

Genomic instability can initiate cancer, augment progression, and influence the overall prognosis of the affected patient. Genomic instability arises from many different pathways, such as telomere damage, centrosome amplification, epigenetic modifications, and DNA damage from endogenous and exogenous sources, and can be perpetuating, or limiting, through the induction of mutations or aneuploidy, both enabling and catastrophic. Many cancer treatments induce DNA damage to impair cell division on a global scale but it is accepted that personalized treatments, those that are tailored to the particular patient and type of cancer, must also be developed. In this review, we detail the mechanisms from which genomic instability arises and can lead to cancer, as well as treatments and measures that prevent genomic instability or take advantage of the cellular defects caused by genomic instability. In particular, we identify and discuss five priority targets against genomic instability: (1) prevention of DNA damage; (2) enhancement of DNA repair; (3) targeting deficient DNA repair; (4) impairing centrosome clustering; and, (5) inhibition of telomerase activity. Moreover, we highlight vitamin D and B, selenium, carotenoids, PARP inhibitors, resveratrol, and isothiocyanates as priority approaches against genomic instability. The prioritized target sites and approaches were cross validated to identify potential synergistic effects on a number of important areas of cancer biology. PMID:25869442

External factors affecting data acquisition during corneal topography examination.

PubMed

González-Méijome, José Manuel; Queirós, Antonio; Jorge, Jorge; Fernandes, Paulo; Cerviño, Alejandro; de Almeida, José Borges

2007-03-01

To analyze the factors affecting data acquisition during corneal topography examination with the Medmont E-300 videokeratoscope and to provide strategies to minimize their effects. Sixty eyes from thirty young adults were examined. A second observer registered incidences with the potential to affect data acquisition. Those factors were correlated with the difficulty of measurements as judged subjectively by the practitioner who performed the examination. Measurements of axial curvature were analyzed to evaluate the variability expressed as intrasession and intersession coefficient of variation and the standard error of the mean (SEM). The level of difficulty rated by the practitioner was in general low, with 70% of the eyes being easy or very easy to measure. For the remaining 30% of the eyes, corneal topography measurements were considered to be difficult (27%) or very difficult (3%). Of the external parameters investigated, only fixation instability (P<0.001, chi2) and the need for head repositioning (P=0.024, chi2) were associated significantly with a higher level of difficulty, as rated subjectively by the practitioner. Further analysis showed that some external factors, including those previously mentioned and others related to tear instability, affect the variability of measurements at certain corneal locations, particularly in the vertical meridian when related to tear instability and in the horizontal meridian when related to the need for head repositioning on the chin rest owing to physiognomy interferences with the keratoscope cone. Intersession SEM improved when three readings from each session were considered. The level of subjective difficulty found during videokeratoscopy examination is correlated strongly with fixation instability and the need for head reorientation in the chin rest, whereas tear-related events seem to be less relevant in the practitioner perception of test ease or difficulty. Those factors have relevance in measurement variability.

[Distribution and origin of plastic resin pellets as environmental pollutants at the East China Sea area].

PubMed

Kaminuma, T; Ohtake, C; Kabuyama, N

2000-01-01

Plastic debris are important marine pollutants. Plastic debris consist of resin pellets and waste plastics. We are particularly interested in resin pellets. We made field survey of resin pellets at nearly 400 sites in 200 beaches in Japan and neighboring countries. The pellets were found at all most all Japan coasts we surveyed and at some beaches of Macao, Hong Kong, Xiamen, the north of Taipei, and Cheju Island in Korea. The number of pellets was more than 1000 pieces per m2 on the most abundant beach in Japan. Through further analysis using GC/ECD, endocrine disrupting chemicals, PCBs, DDTs, HCHs and Nonylphenol were detected in selected samples. Biota such as Bryozoa were observed on the surface of pellets washed up on the beaches in subtropical areas. Pellets has been suspected to affect wildlife and human health, but we have no report on affection to human.

Thermally induced secondary atomization of droplet in an acoustic field

NASA Astrophysics Data System (ADS)

Basu, Saptarshi; Saha, Abhishek; Kumar, Ranganathan

2012-01-01

We study the thermal effects that lead to instability and break up in acoustically levitated vaporizing fuel droplets. For selective liquids, atomization occurs at the droplet equator under external heating. Short wavelength [Kelvin-Helmholtz (KH)] instability for diesel and bio-diesel droplets triggers this secondary atomization. Vapor pressure, latent heat, and specific heat govern the vaporization rate and temperature history, which affect the surface tension gradient and gas phase density, ultimately dictating the onset of KH instability. We develop a criterion based on Weber number to define a condition for the inception of secondary atomization.

Parametric Instability Rates in Periodically Driven Band Systems

NASA Astrophysics Data System (ADS)

Lellouch, S.; Bukov, M.; Demler, E.; Goldman, N.

2017-04-01

In this work, we analyze the dynamical properties of periodically driven band models. Focusing on the case of Bose-Einstein condensates, and using a mean-field approach to treat interparticle collisions, we identify the origin of dynamical instabilities arising from the interplay between the external drive and interactions. We present a widely applicable generic numerical method to extract instability rates and link parametric instabilities to uncontrolled energy absorption at short times. Based on the existence of parametric resonances, we then develop an analytical approach within Bogoliubov theory, which quantitatively captures the instability rates of the system and provides an intuitive picture of the relevant physical processes, including an understanding of how transverse modes affect the formation of parametric instabilities. Importantly, our calculations demonstrate an agreement between the instability rates determined from numerical simulations and those predicted by theory. To determine the validity regime of the mean-field analysis, we compare the latter to the weakly coupled conserving approximation. The tools developed and the results obtained in this work are directly relevant to present-day ultracold-atom experiments based on shaken optical lattices and are expected to provide an insightful guidance in the quest for Floquet engineering.

Statistical Properties of Real-Time Amplitude Estimate of Harmonics Affected by Frequency Instability

NASA Astrophysics Data System (ADS)

Bellan, Diego; Pignari, Sergio A.

2016-07-01

This work deals with the statistical characterization of real-time digital measurement of the amplitude of harmonics affected by frequency instability. In fact, in modern power systems both the presence of harmonics and frequency instability are well-known and widespread phenomena mainly due to nonlinear loads and distributed generation, respectively. As a result, real-time monitoring of voltage/current frequency spectra is of paramount importance as far as power quality issues are addressed. Within this framework, a key point is that in many cases real-time continuous monitoring prevents the application of sophisticated algorithms to extract all the information from the digitized waveforms because of the required computational burden. In those cases only simple evaluations such as peak search of discrete Fourier transform are implemented. It is well known, however, that a slight change in waveform frequency results in lack of sampling synchronism and uncertainty in amplitude estimate. Of course the impact of this phenomenon increases with the order of the harmonic to be measured. In this paper an approximate analytical approach is proposed in order to describe the statistical properties of the measured magnitude of harmonics affected by frequency instability. By providing a simplified description of the frequency behavior of the windows used against spectral leakage, analytical expressions for mean value, variance, cumulative distribution function, and probability density function of the measured harmonics magnitude are derived in closed form as functions of waveform frequency treated as a random variable.

Plastic Faulting in Ice: Shear Localization under Elevated Pressure

NASA Astrophysics Data System (ADS)

Golding, N.; Durham, W. B.

2013-12-01

Ice exhibits, at least, two distinct kinds of shear faults when loaded triaxially under compression. Under moderate levels of confinement, brittle failure follows crack growth, crack coalescence and the development of a fault oriented about 30 degrees from the direction of maximum compression. The mechanism governing this mode of failure, termed frictional or Coulombic faulting, has previously been discussed for ice and rocks in connection with the comb-crack model. Under higher levels of confinement, where frictional sliding is suppressed by confining pressure, failure is characterized by sudden brittle-like loss in load bearing capacity and the development of a narrow shear band, comprised of recrystallized grains, oriented about 45 degrees from the direction of maximum compression, i.e. along the direction of maximum shear. This mode of failure, referred to here as plastic faulting, has previously been discussed for warm ice, T = 233 - 263 K, in connection with adiabatic shear heating and has been discussed for cold ice, T = 77 - 163 K, in connection with phase transformation. Here, new results are presented that examine the mechanical behavior and microstructural properties of plastic faulting in polycrystalline ice loaded at temperatures from T = 175 - 210 K and confining pressures up to P = 200 MPa. The results are reviewed in context of previous work and possible mechanisms to account for shear localization in ice under high pressure, including 1) adiabatic shear heating, 2) grain refinement and 3) phase transformation, are discussed. The present observations highlight the similarities in the behavior of plastic faulting under both warm and cold conditions and suggest adiabatic shear heating as a possible mechanism to account for shear instability and plastic faulting at temperatures ranging from T = 77 - 263 K.

Recurrent Shoulder Instability in a Young, Active, Military Population and Its Professional Implications.

PubMed

Flint, James H; Pickett, Adam; Owens, Brett D; Svoboda, Steven J; Peck, Karen Y; Cameron, Kenneth L; Biery, John; Giuliani, Jeffrey; Rue, John-Paul

Shoulder instability is a topic of significant interest within the sports medicine literature, particularly regarding recurrence rates and the ideal treatment indications and techniques. Little has been published specifically addressing the occupational implications of symptomatic recurrent shoulder instability. Previous arthroscopic repair will continue to be a significant predisposing factor for recurrent instability in a young, active population, and that recurrent instability may have a negative effect on college graduation and postgraduate occupational selection. Case series. Level 4. We conducted a retrospective review of approved medical waivers for surgical treatment of anterior shoulder dislocation or instability prior to matriculation at the US Military Academy or the US Naval Academy for the graduating classes of 2010 to 2013. Statistical analysis was performed to determine the incidence and risk factors for recurrence and to determine the impact on graduation rate and occupation selection. Fifty-nine patients were evaluated; 34% developed recurrent anterior instability. Patients with previous arthroscopic repair had a significantly higher incidence of recurrence (38%, P = 0.044). Recurrent shoulder instability did not significantly affect graduation rates or self-selected occupation ( P ≥ 0.05). There is a significant rate of recurrent shoulder instability after primary surgical repair, particularly among young, active individuals. In addition, arthroscopic repair resulted in a significantly higher recurrence rate compared with open repair in our population. Surgical repair for shoulder instability should not necessarily preclude young individuals from pursuing (or being considered for) occupations that may place them at greater risk of recurrence. The risk of recurrent instability is greater than the rate typically described, which may suggest that some subpopulations are at greater risk than others. A unique data point regarding instability is the effect on occupation selection.

Relativistic electromagnetic ion cyclotron instabilities

NASA Astrophysics Data System (ADS)

Chen, K. R.; Huang, R. D.; Wang, J. C.; Chen, Y. Y.

2005-03-01

The relativistic instabilities of electromagnetic ion cyclotron waves driven by MeV ions are analytically and numerically studied. As caused by wave magnetic field and in sharp contrast to the electrostatic case, interesting characteristics such as Alfvénic behavior and instability transition are discovered and illuminated in detail. The instabilities are reactive and are raised from the coupling of slow ions’ first-order resonance and fast ions’ second-order resonance, that is an essential extra mechanism due to relativistic effect. Because of the wave magnetic field, the nonresonant plasma dielectric is usually negative and large, that affects the instability conditions and scaling laws. A negative harmonic cyclotron frequency mismatch between the fast and slow ions is required for driving a cubic (and a coupled quadratic) instability; the cubic (square) root scaling of the peak growth rate makes the relativistic effect more important than classical mechanism, especially for low fast ion density and Lorentz factor being close to unity. For the cubic instability, there is a threshold (ceiling) on the slow ion temperature and density (the external magnetic field and the fast ion energy); the Alfvén velocity is required to be low. This Alfvénic behavior is interesting in physics and important for its applications. The case of fast protons in thermal deuterons is numerically studied and compared with the analytical results. When the slow ion temperature or density (the external magnetic field or the fast ion energy) is increased (reduced) to about twice (half) the threshold (ceiling), the same growth rate peak transits from the cubic instability to the coupled quadratic instability and a different cubic instability branch appears. The instability transition is an interesting new phenomenon for instability.

Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain.

PubMed

Mattsson, Karin; Johnson, Elyse V; Malmendal, Anders; Linse, Sara; Hansson, Lars-Anders; Cedervall, Tommy

2017-09-13

The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour and metabolism of organisms remains elusive. Here we demonstrate that plastic nanoparticles reduce survival of aquatic zooplankton and penetrate the blood-to-brain barrier in fish and cause behavioural disorders. Hence, for the first time, we uncover direct interactions between plastic nanoparticles and brain tissue, which is the likely mechanism behind the observed behavioural disorders in the top consumer. In a broader perspective, our findings demonstrate that plastic nanoparticles are transferred up through a food chain, enter the brain of the top consumer and affect its behaviour, thereby severely disrupting the function of natural ecosystems.

A Home-Made Trap Baited With Sex Pheromone for Monitoring Spodoptera Frugiperda Males (Lepidoptera: Noctuidae) in Corn crops in Mexico.

PubMed

Malo, Edi A; Cruz-Esteban, Samuel; González, Francisco J; Rojas, Julio C

2018-05-15

Fall armyworm (FAW), Spodoptera frugiperda (J. E. Smith), populations are monitored with a variety of commercial sex pheromone-baited traps. However, a number of trap-related variables may affect the number of FAW males captured. In this study, we tested the effect of trap design, trap size, and trap color for monitoring FAW males in corn crops in Mexico. We found that plastic jug trap (a home-made trap), captured significantly more FAW males than a commercial trap (Scentry Heliothis) and water bottle trap (another home-made trap). We also found that size of plastic jug traps (3.78, 10, or 20 liters) did not affect the captures of FAW males. Our results indicated that plastic yellow jug traps captured significantly more males than blue and black traps. Plastic jug white, red, and green traps captured a similar number of FAW males than plastic jug yellow, blue, and black traps. Plastic jug blue, white, and yellow traps captured more nontarget insects compared to black traps. The number of nontarget insects captured by green and red traps was similar and not significantly different to that caught by blue, white, yellow, and black traps. Traps captured more individuals from Diptera than Coleoptera and Hymenoptera. Overall, the results suggest that yellow plastic jug may be used for monitoring FAW males in corn and sorghum crops in Mexico.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Yunliang; International Centre for Advanced Studies in Physical Sciences and Institute for Theoretical Physics, Faculty of Physics and Astronomy, Ruhr University Bochum, D-44780 Bochum; Lü, Xiaoxia

A theoretical and numerical study of the modulational instability of large amplitude quantum magnetosonic waves (QMWs) in a relativistically degenerate plasma is presented. A modified nonlinear Schrödinger equation is derived by using the reductive perturbation method. The modulational instability regions of the QMWs and the corresponding growth rates are significantly affected by the relativistic degeneracy parameter, the Pauli spin magnetization effects, and the equilibrium magnetic field. The dynamics and nonlinear saturation of the modulational instability of QMWs are investigated numerically. It is found that the increase of the relativistic degeneracy parameter can increase the growth rate of the instability, andmore » the system is saturated nonlinearly by the formation of envelope solitary waves. The current investigation may have relevance to astrophysical magnetized compact objects, such as white dwarfs and pulsar magnetospheres.« less

Modulational instability and discrete breathers in a nonlinear helicoidal lattice model

NASA Astrophysics Data System (ADS)

Ding, Jinmin; Wu, Tianle; Chang, Xia; Tang, Bing

2018-06-01

We investigate the problem on the discrete modulation instability of plane waves and discrete breather modes in a nonlinear helicoidal lattice model, which is described by a discrete nonlinear Schrödinger equation with the first-, second-, and third-neighbor coupling. By means of the linear stability analysis, we present an analytical expression of the instability growth rate and identify the regions of modulational instability of plane waves. It is shown that the introduction of the third-neighbor coupling will affect the shape of the areas of modulational instability significantly. Based on the results obtained by the modulational instability analysis, we predict the existence conditions for the stationary breather modes. Otherwise, by making use of the semidiscrete multiple-scale method, we obtain analytical solutions of discrete breather modes and analyze their properties for different types of nonlinearities. Our results show that the discrete breathers obtained are stable for a long time only when the system exhibits the repulsive nonlinearity. In addition, it is found that the existence of the stable bright discrete breather closely relates to the presence of the third-neighbor coupling.

On the nonlinear stability of a high-speed, axisymmetric boundary layer

NASA Technical Reports Server (NTRS)

Pruett, C. David; Ng, Lian L.; Erlebacher, Gordon

1991-01-01

The stability of a high-speed, axisymmetric boundary layer is investigated using secondary instability theory and direct numerical simulation. Parametric studies based on the temporal secondary instability theory identify subharmonic secondary instability as a likely path to transition on a cylinder at Mach 4.5. The theoretical predictions are validated by direct numerical simulation at temporally-evolving primary and secondary disturbances in an axisymmetric boundary-layer flow. At small amplitudes of the secondary disturbance, predicted growth rates agree to several significant digits with values obtained from the spectrally-accurate solution of the compressible Navier-Stokes equations. Qualitative agreement persists to large amplitudes of the secondary disturbance. Moderate transverse curvature is shown to significantly affect the growth rate of axisymmetric second mode disturbances, the likely candidates of primary instability. The influence of curvature on secondary instability is largely indirect but most probably significant, through modulation of the primary disturbance amplitude. Subharmonic secondary instability is shown to be predominantly inviscid in nature, and to account for spikes in the Reynolds stress components at or near the critical layer.

Non-thermal electron distribution functions through 3D magnetic reconnection instabilities in the solar wind

NASA Astrophysics Data System (ADS)

Alejandro Munoz Sepulveda, Patricio; Buechner, Joerg

2017-04-01

The effects of kinetic instabilities on the solar wind electron velocity distribution functions (eVDFs) are mostly well understood under local homogeneous and stationary conditions. But the solar wind also contains current sheets, which affect the local properties of instabilities, turbulence and thus the observed non-maxwellian features in the eVDFs. Those processes are vastly unexplored. Therefore, we aim to investigate the influence of self-consistently generated turbulence via electron-scale instabilities in reconnecting current sheets on the formation of suprathermal features in the eVDFs. For this sake, we carry out 3D fully-kinetic Particle-in-Cell code numerical simulations of force free current sheets with a guide magnetic field. We find extended tails, anisotropic plateaus and non-gyrotropic features in the eVDFs, correlated with the locations and time where micro-turbulence is enhanced in the current sheet due to current-aligned streaming instabilities. We also discuss the influence of the plasma parameters, such as the ion to electron temperature ratio, on the excitation of current sheet instabilities and their effect on the properties of the eVDFs.

Real-Time Wavelength Discrimination for Improved Neutron Discrimination in CLYC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hornback, Donald Eric; Hu, Michael Z.; Bell, Zane W.

We investigated the effects of optical filters on the pulse shape discrimination properties of Cs 2LiYCl 6:Ce (CLYC) scintillator crystals. By viewing the scintillation light through various optical filters, we attempted to better distinguish between neutron and gamma ray events in the crystal. We applied commercial interference and colored glass filters in addition to fabricating quantum dot (QD) filters by suspending QDs in plastic films and glass. QD filters ultimately failed because of instability of the QDs with respect to oxidation when exposed to ambient air, and the tendency of the QDs to aggregate in the plastic. Of the commercialmore » filters, the best results were obtained with a bandpass interference filter covering the spectral region containing core-valence luminescence (CVL) light. However, the PSD response of filtered CLYC light was always poorer than the response exhibited by unfiltered light because filters always reduced the amount of light available for signal processing.« less

How Plastics Work

NASA Astrophysics Data System (ADS)

Bloomfield, Louis

2013-03-01

We encounter plastics every day, but despite their widespread use, amazing range of properties, and basic scientific underpinnings, most physicists--like most people--know relatively little about plastics. In contrast to hard crystalline and amorphous solids (e.g., metals, salts, ceramics, and glasses), we take plastics for granted, select them carelessly, and examine them more closely only on a need-to-know basis. By ignoring plastics until we need them, however, we risk not knowing what we don't know and using the wrong ones. To repurpose a familiar advertisement, ``there's a plastic for that.'' This talk will review some of the basic physics and science of plastics. It will examine the roles of temperature, order, intermolecular forces, entanglements, and linkages in plastics, and how those issues affect the properties of a given plastic. We'll stop along the way to recognize a few of the more familiar plastics, natural and synthetic, and explain some of their mechanical, chemical, and optical properties. The talk will conclude by explaining the remarkable properties of a plastic that has been largely misunderstood since its discovery 70 years ago: Silly Putty.

How high energy fluxes may affect Rayleigh-Taylor instability growth in young supernova remnants

NASA Astrophysics Data System (ADS)

Kuranz, C. C.; Park, H.-S.; Huntington, C. M.; Miles, A. R.; Remington, B. A.; Drake, R. P.; Tranthan, M. A.; Handy, T. A.; Shvarts, D.; Malamud, G.; Shimony, A.; Shvarts, D.; Kline, J.; Flippo, K. A.; Doss, F. W.; Plewa, T.

2017-10-01

Energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Simulations predict that RT produces structures at this interface, having a range of spatial scales. When the CSM is dense enough, as in the case of SN 1993J, the hot shocked matter can produce significant radiative fluxes that affect the emission from the SNR. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae such as SN 1993J, might affect this structure. We present data and simulations from Rayleigh-Taylor instability experiments in high- and low- energy flux experiments performed at the National Ignition Facility. We also will discuss the apparent, larger role of heat conduction when we closely examined the comparison between the experimental results, and the SNR observations and models. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0002956.

Electromiography comparison of distal and proximal lower limb muscle activity patterns during external perturbation in subjects with and without functional ankle instability.

PubMed

Kazemi, Khadijeh; Arab, Amir Massoud; Abdollahi, Iraj; López-López, Daniel; Calvo-Lobo, César

2017-10-01

Ankle sprain is one of the most common injuries among athletes and the general population. Most ankle injuries commonly affect the lateral ligament complex. Changes in postural sway and hip abductor muscle strength may be generated after inversion ankle sprain. Therefore, the consequences of ankle injury may affect proximal structures of the lower limb. The aim is to describe and compare the activity patterns of distal and proximal lower limb muscles following external perturbation in individuals with and without functional ankle instability. The sample consisted of 16 women with functional ankle instability and 18 healthy women were recruited to participate in this research. The external perturbation via body jacket using surface electromyography, amplitude and onset of muscle activity of gluteus maximums, gluteus medius, tibialis anterior, and peroneus longus was recorded and analyzed during external perturbation. There were differences between the onset of muscles activity due to perturbation direction in the two groups (healthy and functional ankle instability). In the healthy group, there were statistically significant differences in amplitude of proximal muscle activity with distal muscle activity during front perturbation with eyes open and closed. In the functional ankle instability group; there were statistically significant differences in amplitude of proximal muscle activity with distal muscle activity during perturbation of the front and back with eyes open. There were statistically significant differences in the onset of muscle activity and amplitude of muscle activity, with-in and between groups (P<0.05). Therefore, in the presence of functional ankle instability, activation patterns of the lower limb proximal muscles may be altered. Copyright © 2017 Elsevier B.V. All rights reserved.

The study of high-speed surface dynamics using a pulsed proton beam

NASA Astrophysics Data System (ADS)

Buttler, William T.; Oro, David M.; Preston, Dean; Mikaelian, Karnig O.; Cherne, Frank J.; Hixson, Robert S.; Mariam, Fesseha G.; Morris, Christopher L.; Stone, Joseph B.; Terrones, Guillermo; Tupa, Dale

2012-03-01

We present experimental results supporting physics based ejecta model development, where we assume ejecta form as a special limiting case of a Richtmyer-Meshkov (RM) instability with Atwood number A = -1. We present and use data to test established RM spike and bubble growth rate theory through application of modern laser Doppler velocimetry techniques applied in a novel manner to coincidentally measure bubble and spike velocities from shocked metals. We also explore the link of ejecta formation from a solid material to its plastic flow stress at high-strain rates (107/s) and high strains (700%).

Effect of an aggressive medium on discontinuous deformation of aluminum-magnesium alloy AlMg6

NASA Astrophysics Data System (ADS)

Shibkov, A. A.; Denisov, A. A.; Zolotov, A. E.; Kochegarov, S. S.

2017-01-01

It is experimentally shown that the molecular (chemical) process of surface etching of deformed aluminum-magnesium alloy AlMg6 causes the development of a macroscopic plastic strain step with an amplitude of a few percent. Using numerical simulation of the polycrystalline solid etching process, it is shown that the corrosion front morphology varies during etching from Euclid (flat) to fractal (rough). The results obtained show the key role of the surface state on the development of macroscopic mechanical instability of a material exhibiting the Portevin-Le Chatelier effect.

Stress corrosion cracking of titanium alloys

NASA Technical Reports Server (NTRS)

Statler, G. R.; Spretnak, J. W.; Beck, F. H.; Fontana, M. G.

1974-01-01

The effect of hydrogen on the properties of metals, including titanium and its alloys, was investigated. The basic theories of stress corrosion of titanium alloys are reviewed along with the literature concerned with the effect of absorbed hydrogen on the mechanical properties of metals. Finally, the basic modes of metal fracture and their importance to this study is considered. The experimental work was designed to determine the effects of hydrogen concentration on the critical strain at which plastic instability along pure shear directions occurs. The materials used were titanium alloys Ti-8Al-lMo-lV and Ti-5Al-2.5Sn.

Affective and Self-Esteem Instability in the Daily Lives of People with Generalized Social Anxiety Disorder

PubMed Central

Farmer, Antonina S.; Kashdan, Todd B.

2014-01-01

Research on affect and self-esteem in social anxiety disorder (SAD) has focused on trait or average levels, but we know little about the dynamic patterns of these experiences in the daily lives of people with SAD. We asked 40 adults with SAD and 39 matched healthy controls to provide end-of-day reports on their affect and self-esteem over two weeks. Compared to healthy adults, participants with SAD exhibited greater instability of negative affect and self-esteem, though the self-esteem effect was driven by mean level differences. The SAD group also demonstrated a higher probability of acute changes in negative affect and self-esteem (i.e., from one assessment period to the next), as well as difficulty maintaining positive states and improving negative states (i.e., dysfunctional self-regulation). Our findings provide insights on the phenomenology of SAD, with particular attention to the temporal dependency, magnitude of change, and directional patterns of psychological experiences in everyday life. PMID:25821659

How noise affects the synchronization properties of recurrent networks of inhibitory neurons.

PubMed

Brunel, Nicolas; Hansel, David

2006-05-01

GABAergic interneurons play a major role in the emergence of various types of synchronous oscillatory patterns of activity in the central nervous system. Motivated by these experimental facts, modeling studies have investigated mechanisms for the emergence of coherent activity in networks of inhibitory neurons. However, most of these studies have focused either when the noise in the network is absent or weak or in the opposite situation when it is strong. Hence, a full picture of how noise affects the dynamics of such systems is still lacking. The aim of this letter is to provide a more comprehensive understanding of the mechanisms by which the asynchronous states in large, fully connected networks of inhibitory neurons are destabilized as a function of the noise level. Three types of single neuron models are considered: the leaky integrate-and-fire (LIF) model, the exponential integrate-and-fire (EIF), model and conductance-based models involving sodium and potassium Hodgkin-Huxley (HH) currents. We show that in all models, the instabilities of the asynchronous state can be classified in two classes. The first one consists of clustering instabilities, which exist in a restricted range of noise. These instabilities lead to synchronous patterns in which the population of neurons is broken into clusters of synchronously firing neurons. The irregularity of the firing patterns of the neurons is weak. The second class of instabilities, termed oscillatory firing rate instabilities, exists at any value of noise. They lead to cluster state at low noise. As the noise is increased, the instability occurs at larger coupling, and the pattern of firing that emerges becomes more irregular. In the regime of high noise and strong coupling, these instabilities lead to stochastic oscillations in which neurons fire in an approximately Poisson way with a common instantaneous probability of firing that oscillates in time.

Systematic Review of Postural Control and Lateral Ankle Instability, Part I: Can Deficits Be Detected With Instrumented Testing

PubMed Central

McKeon, Patrick O; Hertel, Jay

2008-01-01

Objective: To answer the following clinical questions: (1) Is poor postural control associated with increased risk of a lateral ankle sprain? (2) Is postural control adversely affected after acute lateral ankle sprain? (3) Is postural control adversely affected in those with chronic ankle instability? Data Sources: PubMed and CINAHL entries from 1966 through October 2006 were searched using the terms ankle sprain, ankle instability, balance, chronic ankle instability, functional ankle instability, postural control, and postural sway. Study Selection: Only studies assessing postural control measures in participants on a stable force plate performing the modified Romberg test were included. To be included, a study had to address at least 1 of the 3 clinical questions stated above and provide adequate results for calculation of effect sizes or odds ratios where applicable. Data Extraction: We calculated odds ratios with 95% confidence intervals for studies assessing postural control as a risk factor for lateral ankle sprains. Effect sizes were estimated with the Cohen d and associated 95% confidence intervals for comparisons of postural control performance between healthy and injured groups, or healthy and injured limbs, respectively. Data Synthesis: Poor postural control is most likely associated with an increased risk of sustaining an acute ankle sprain. Postural control is impaired after acute lateral ankle sprain, with deficits identified in both the injured and uninjured sides compared with controls. Although chronic ankle instability has been purported to be associated with altered postural control, these impairments have not been detected consistently with the use of traditional instrumented measures. Conclusions: Instrumented postural control testing on stable force plates is better at identifying deficits that are associated with an increased risk of ankle sprain and that occur after acute ankle sprains than at detecting deficits related to chronic ankle instability. PMID:18523566

Stand-alone lumbar cage subsidence: A biomechanical sensitivity study of cage design and placement.

PubMed

Calvo-Echenique, Andrea; Cegoñino, José; Chueca, Raúl; Pérez-Del Palomar, Amaya

2018-08-01

Spinal degeneration and instability are commonly treated with interbody fusion cages either alone or supplemented with posterior instrumentation with the aim to immobilise the segment and restore intervertebral height. The purpose of this work is to establish a tool which may help to understand the effects of intervertebral cage design and placement on the biomechanical response of a patient-specific model to help reducing post-surgical complications such as subsidence and segment instability. A 3D lumbar functional spinal unit (FSU) finite element model was created and a parametric model of an interbody cage was designed and introduced in the FSU. A Drucker-Prager Cap plasticity formulation was used to predict plastic strains and bone failure in the vertebrae. The effect of varying cage size, cross-sectional area, apparent stiffness and positioning was evaluated under 500 N preload followed by 7.5 Nm multidirectional rotation and the results were compared with the intact model. The most influential cage parameters on the FSU were size, curvature congruence with the endplates and cage placement. Segmental stiffness was higher when increasing the cross-sectional cage area in all loading directions and when the cage was anteriorly placed in all directions but extension. In general, the facet joint forces were reduced by increasing segmental stiffness. However, these forces were higher than in the intact model in most of the cases due to the displacement of the instantaneous centre of rotation. The highest plastic deformations took place at the caudal vertebra under flexion and increased for cages with greater stiffness. Thus, wider cages and a more anteriorly placement would increase the volume of failed bone and, therefore, the risk of subsidence. Cage geometry plays a crucial role in the success of lumbar surgery. General considerations such as larger cages may be applied as a guideline, but parameters such as curvature or cage placement should be determined for each specific patient. This model provides a proof-of-concept of a tool for the preoperative evaluation of lumbar surgical outcomes. Copyright © 2018 Elsevier B.V. All rights reserved.

Strain Rate Effect on Tensile Flow Behavior and Anisotropy of a Medium-Manganese TRIP Steel

NASA Astrophysics Data System (ADS)

Alturk, Rakan; Hector, Louis G.; Matthew Enloe, C.; Abu-Farha, Fadi; Brown, Tyson W.

2018-06-01

The dependence of the plastic anisotropy on the nominal strain rate for a medium-manganese (10 wt.% Mn) transformation-induced plasticity (TRIP) steel with initial austenite volume fraction of 66% (balance ferrite) has been investigated. The material exhibited yield point elongation, propagative instabilities during hardening, and austenite transformation to α'-martensite either directly or through ɛ-martensite. Uniaxial strain rates within the range of 0.005-500 s-1 along the 0°, 45°, and 90° orientations were selected based upon their relevance to automotive applications. The plastic anisotropy ( r) and normal anisotropy ( r n) indices corresponding to each direction and strain rate were determined using strain fields obtained from stereo digital image correlation systems that enabled both quasistatic and dynamic measurements. The results provide evidence of significant, orientation-dependent strain rate effects on both the flow stress and the evolution of r and r n with strain. This has implications not only for material performance during forming but also for the development of future strain-rate-dependent anisotropic yield criteria. Since tensile data alone for the subject medium-manganese TRIP steel do not satisfactorily determine the microstructural mechanisms responsible for the macroscopic-scale behavior observed on tensile testing, additional tests that must supplement the mechanical test results presented herein are discussed.

Strain Rate Effect on Tensile Flow Behavior and Anisotropy of a Medium-Manganese TRIP Steel

NASA Astrophysics Data System (ADS)

Alturk, Rakan; Hector, Louis G.; Matthew Enloe, C.; Abu-Farha, Fadi; Brown, Tyson W.

2018-04-01

The dependence of the plastic anisotropy on the nominal strain rate for a medium-manganese (10 wt.% Mn) transformation-induced plasticity (TRIP) steel with initial austenite volume fraction of 66% (balance ferrite) has been investigated. The material exhibited yield point elongation, propagative instabilities during hardening, and austenite transformation to α'-martensite either directly or through ɛ-martensite. Uniaxial strain rates within the range of 0.005-500 s-1 along the 0°, 45°, and 90° orientations were selected based upon their relevance to automotive applications. The plastic anisotropy (r) and normal anisotropy (r n) indices corresponding to each direction and strain rate were determined using strain fields obtained from stereo digital image correlation systems that enabled both quasistatic and dynamic measurements. The results provide evidence of significant, orientation-dependent strain rate effects on both the flow stress and the evolution of r and r n with strain. This has implications not only for material performance during forming but also for the development of future strain-rate-dependent anisotropic yield criteria. Since tensile data alone for the subject medium-manganese TRIP steel do not satisfactorily determine the microstructural mechanisms responsible for the macroscopic-scale behavior observed on tensile testing, additional tests that must supplement the mechanical test results presented herein are discussed.

On the Plasticity of Amorphous Solids

NASA Astrophysics Data System (ADS)

Lin, Jie

Mechanical behaviors of amorphous materials under external stress are central to various phenomena including earthquakes and landslides. Most amorphous materials possess a well defined yield stress when thermal fluctuations are negligible. Only when the shear stress is above the yield stress, the material can flow as a fluid, otherwise it deforms as a solid. There are accumulating evidences that the yielding transition between the flowing and solid phase is a critical phenomenon, and one evidence is the long ranged correlations of plastic strain during adiabatic shear. In spite of this, we still have not fully understood the associated critical exponents and their scaling relations. In the last decade, it has been widely accepted that the elementary rearrangements in amorphous solids are not well-defined topological defects as crystals, instead they are local irreversible rearrangements of a few particles, denoted as shear transformations. Because a single shear transformation changes the local arrangement of particles, it therefore generates an elastic stress field propagating over the whole system. The resulting changes in the local stresses in other regions of the system may in turn trigger more shear transformations. A central feature that complicates the yielding transition is the long range and anisotropic stress field generated by shear transformations. This peculiar interaction between shear transformations leads to two important characteristics: 1.the mechanical noises generated by plastic deformation are broadly distributed 2.those regions that are undergoing plastic deformation has equal probability to make other parts of the material to be more stable or more unstable, depending on the direction between them. In this thesis, we show that these two important factors leads to a singular density of shear transformations, P( x) xtheta at small x, where x is a local measure of stability, namely, the extra stress one needs to add locally to reach the elastic instabilities. We denote such a singular distribution as a pseudo gap, and the theta exponent as the pseudo gap exponent. The fact that the plastic avalanche rates, i.e., number of avalanches per unit strain, during quasi-static shear is not proportional to system size implies the existence of a finite pseudo gap exponent. Arguments based on stability against local perturbations lead to a lower bound of the pseudo gap exponents. In the flowing phase, we construct the scaling description of the yielding transition of soft amorphous solids at zero temperature. The yielding transition shares similarities with another well studied dynamic phase transition, the depinning transition where an elastic interface is driven in a disordered medium, however, there are also striking differences between them. Avalanches are fractal in the yielding transition, characterized by a fractal dimension smaller than the spatial dimension, while avalanches are compact with a fractal dimension, not smaller than the spatial dimension in the depinning transition. We make connections between the Herschel-Bulkley exponent characterizing the singularity of the flow curve near the yield stress, the extension and duration of the avalanches of plasticity, and the pseudo gap exponent. On the other hand, in the solid phase, the pseudo gap also plays a significant role as one increases the shear stress adiabatically. We point out the connection between the local slope of stress-strain curve in the transient state and mean avalanche sizes as the system approaches failure. We argue that the entire solid phase below the yield stress is critical as long as there is finite amount of plastic strain, and plasticity always involves system-spanning events because of the finite pseudo gap exponent. We use the elasto-plastic model, a mesoscopic approach, to verify our theoretical predictions and obtain satisfying results. Finally, a mean field description of plastic flow in amorphous solids are proposed and solved analytically. The mean field models captures the broad distribution of mechanical noise generated by plasticity, leading to a biased Levy flight behavior of local stresses, with the elastic instabilities as the absorbing boundary. The mean field model implies an upper critical dimension as dc = 4.

Effects of fatiguing treadmill running on sensorimotor control in athletes with and without functional ankle instability.

PubMed

Steib, Simon; Hentschke, Christian; Welsch, Goetz; Pfeifer, Klaus; Zech, Astrid

2013-08-01

Sensorimotor control is permanently impaired following functional ankle instability and temporarily decreased following fatigue. Little is known on potential interactions between both conditions. The purpose was to investigate the effect of fatiguing exercise on sensorimotor control in athletes with and without (coper, controls) functional ankle instability. 19 individuals with functional ankle instability, 19 ankle sprain copers, and 19 non-injured controls participated in this cohort study. Maximum reach distance in the star excursion balance test, unilateral jump landing stabilization time, center of pressure sway velocity in single-leg-stance, and passive ankle joint position sense were assessed before and immediately after fatiguing treadmill running. A three factorial linear mixed model was specified for each outcome to evaluate the effects of group, exhausting exercise (fatigue) and their interactions (group by fatigue). Effect sizes were calculated as Cohen's d. Maximum reach distance in the star excursion balance test, jump stabilization time and sway velocity, but not joint position sense, were negatively affected by fatigue in all groups. Effect sizes were moderate, ranging from 0.27 to 0.68. No significant group by fatigue interactions were found except for one measure. Copers showed significantly larger prefatigue to postfatigue reductions in anterior reach direction (P≤0.001; d=-0.55) compared to the ankle instability (P=0.007) and control group (P=0.052). Fatiguing exercise negatively affected postural control but not proprioception. Ankle status did not appear to have an effect on fatigue-induced sensorimotor control impairments. © 2013.

All-inside arthroscopic lateral collateral ligament repair for ankle instability with a knotless suture anchor technique.

PubMed

Vega, Jordi; Golanó, Pau; Pellegrino, Alexandro; Rabat, Eduard; Peña, Fernando

2013-12-01

Recently, arthroscopic-assisted techniques have been described to treat lateral ankle instability with excellent results. However, complications including neuritis of the superficial peroneal or sural nerve, and pain or discomfort due to a prominent anchor or suture knot have been reported. The aim of this study was to describe a novel technique, the "all-inside arthroscopic lateral collateral ankle ligament repair," and its results for treating patients with ankle instability. Sixteen patients (10 men and 6 women, mean age 29.3 years, 17-46) with lateral ankle instability were treated with an arthroscopic procedure. Using a suture passer and a knotless anchor, the ligaments were repaired with an all-inside technique. The right ankle was affected in 10 cases. Mean follow-up was 22.3 (12-35) months. On arthroscopic examination, 13 patients had an isolated anterior talofibular ligament (ATFL) injury, and in 3 patients, both the ATFL and calcaneofibular ligament (CFL) were affected. All-inside arthroscopic anatomic repair of the lateral collateral ligament complex was performed in all cases. All patients reported subjective improvement of their ankle instability. The mean AOFAS score increased from 67 preoperatively to 97 at final follow-up. No major complications were reported. The all-inside arthroscopic ligament repair was a safe, reliable, and reproducible technique that both provided an anatomic repair of the lateral collateral ligament complex and restored ankle stability while preserving all the advantages of an arthroscopic technique. Level IV, retrospective case series.

Ingestion of plastic marine debris by longnose lancetfish (Alepisaurus ferox) in the North Pacific Ocean.

PubMed

Jantz, Lesley A; Morishige, Carey L; Bruland, Gregory L; Lepczyk, Christopher A

2013-04-15

Plastic marine debris affects species on most trophic levels, including pelagic fish. While plastic debris ingestion has been investigated in planktivorous fish in the North Pacific Ocean, little knowledge exists on piscivorous fish. The objectives of this study were to determine the frequency of occurrence and the composition of ingested plastic marine debris in longnose lancetfish (Alepisaurus ferox), a piscivorous fish species captured in the Hawaii-based pelagic longline fishery. Nearly a quarter (47 of 192) of A. ferox sampled contained plastic marine debris, primarily in the form of plastic fragments (51.9%). No relationship existed between size (silhouette area) or amount of plastic marine debris ingested and morphometrics of A. ferox. Although A. ferox are not consumed by humans, they are common prey for fish commercially harvested for human consumption. Further research is needed to determine residence time of ingested plastic marine debris and behavior of toxins associated with plastic debris. Published by Elsevier Ltd.

Plastic accumulation in the Mediterranean sea.

PubMed

Cózar, Andrés; Sanz-Martín, Marina; Martí, Elisa; González-Gordillo, J Ignacio; Ubeda, Bárbara; Gálvez, José Á; Irigoien, Xabier; Duarte, Carlos M

2015-01-01

Concentrations of floating plastic were measured throughout the Mediterranean Sea to assess whether this basin can be regarded as a great accumulation region of plastic debris. We found that the average density of plastic (1 item per 4 m2), as well as its frequency of occurrence (100% of the sites sampled), are comparable to the accumulation zones described for the five subtropical ocean gyres. Plastic debris in the Mediterranean surface waters was dominated by millimeter-sized fragments, but showed a higher proportion of large plastic objects than that present in oceanic gyres, reflecting the closer connection with pollution sources. The accumulation of floating plastic in the Mediterranean Sea (between 1,000 and 3,000 tons) is likely related to the high human pressure together with the hydrodynamics of this semi-enclosed basin, with outflow mainly occurring through a deep water layer. Given the biological richness and concentration of economic activities in the Mediterranean Sea, the affects of plastic pollution on marine and human life are expected to be particularly frequent in this plastic accumulation region.

The effects of perturbations on the strain distribution in numerical simulations - elasto-viscoplastic modeling of boudinage as a case study

NASA Astrophysics Data System (ADS)

Peters, Max; Karrech, Ali; Poulet, Thomas; Herwegh, Marco; Regenauer-Lieb, Klaus

2014-05-01

During necking of a mechanically stiffer layer embedded in a weaker matrix, relatively large amounts of strain localize in small areas. As this deformation style appears under distinct geological conditions, necking phenomena, e.g. boudinaged veins, are associated with a variety of deformation modes. So far, there exists rather limited knowledge about the origin of instabilities and their role as precursory structures, i.e. strong localization of elastic energy affecting further plastic deformation (e.g. Regenauer-Lieb & Yuen, 1998; 2004; Karrech et al., 2011a). We applied the finite element solver ABAQUS in order to investigate the 2-D strain distribution in layers including different mechanical material properties during plane strain co-axial deformation. First, linear perturbation analyses were performed in order to evaluate the imperfection sensitivity in the elastic and viscous regimes. We perform a classical modal analysis to determine the natural mode shapes and frequencies of our geological structure during arbitrary vibrations. This analysis aims at detecting the eigenmodes of the geological structure, which are sinusoidal vibrations with geometry specific natural modal shapes and frequencies. The eigenvalues represent the nodal points where the onset of (visco)-elasto-plastic localization can initiate in the structure (Rice, 1977). The eigenmodes, eigenvalues and eigenvectors are highly sensitive to the layer-box' aspect ratio and differences in Young's moduli, or effective viscosity, respectively. Boundary effect-free strain propagation occurs for layer-box aspect ratios smaller than 1:10. Second, these preloading structures were used as seeds for imperfections in elasto-viscoplastic numerical modeling of continuous necking of a coarse-grained mineral layer embedded in a finer-grained matrix (pinch-and-swell type of boudinage), following the thermo-mechanical coupling of grain size evolutions by Herwegh et al. (in press). The evolution of symmetric necks seems to coincide with the transition from dislocation to diffusion creep dominated viscous flow with dramatic grain size reduction and grain growth from swell to neck, respectively, at relatively high extensional strains. Strain propagates from initial stress concentrations in the layer (necks) at an angle of 45° into the matrix, in form of conjugate shear band sets. Preliminary results show that pre-calculated eigenmodes (and corresponding imperfection sizes) amplify these concentrations and lead to a significant reduction of computational time for individual simulations. Moreover, the strain imperfections seeded around the pre-calculated distribution severely change the geometry of necking structures and amount of accommodated plastic strain. We reveal that elastic stress concentrations control localized visco-plastic deformation, which is expressed in the plastic strain energy increase in necking structures. These findings underline the importance of the transient (elasticity and strain hardening) deformation regimes as triggers for plastic deformation and the need for thermodynamics-based (total) energy considerations. REFERENCES Herwegh, M., Poulet, T., Karrech, A. and Regenauer-Lieb, K. (in press). From transient to steady state deformation and grain size: A thermodynamic approach using elasto-visco-plastic numerical modeling. Journal of Geophysical Research. Karrech, A., Regenauer-Lieb, K. and Poulet, T. (2011a). A Damaged visco-plasticity model for pressure and temperature sensitive geomaterials. Journal of Engineering Science 49. Regenauer-Lieb, K., Yuen, D., 1998: Rapid conversion of elastic energy into plastic shear heating during incipient necking of the lithosphere. Geophysical Research Letters, 25. Regenauer-Lieb, K., Yuen, D., 2004. Positive feedback of interacting ductile faults from coupling of equation of state, rheology and thermal-mechanics. Physics of the Earth and Planetary Interiors, 142. Rice, J. R. (1977). The localization of plastic deformation. Theoretical and Applied Mechanics. W. T. Koiter. Amsterdam, North-Holland: 207-220.

Will phenotypic plasticity affecting flowering phenology keep pace with climate change?

PubMed

Richardson, Bryce A; Chaney, Lindsay; Shaw, Nancy L; Still, Shannon M

2017-06-01

Rising temperatures have begun to shift flowering time, but it is unclear whether phenotypic plasticity can accommodate projected temperature change for this century. Evaluating clines in phenological traits and the extent and variation in plasticity can provide key information on assessing risk of maladaptation and developing strategies to mitigate climate change. In this study, flower phenology was examined in 52 populations of big sagebrush (Artemisia tridentata) growing in three common gardens. Flowering date (anthesis) varied 91 days from late July to late November among gardens. Mixed-effects modeling explained 79% of variation in flowering date, of which 46% could be assigned to plasticity and genetic variation in plasticity and 33% to genetics (conditional R 2  = 0.79, marginal R 2  = 0.33). Two environmental variables that explained the genetic variation were photoperiod and the onset of spring, the Julian date of accumulating degree-days >5 °C reaching 100. The genetic variation was mapped for contemporary and future climates (decades 2060 and 2090), showing flower date change varies considerably across the landscape. Plasticity was estimated to accommodate, on average, a ±13-day change in flowering date. However, the examination of genetic variation in plasticity suggests that the magnitude of plasticity could be affected by variation in the sensitivity to photoperiod and temperature. In a warmer common garden, lower-latitude populations have greater plasticity (+16 days) compared to higher-latitude populations (+10 days). Mapped climatypes of flowering date for contemporary and future climates illustrate the wide breadth of plasticity and large geographic overlap. Our research highlights the importance of integrating information on genetic variation, phenotypic plasticity and climatic niche modeling to evaluate plant responses and elucidate vulnerabilities to climate change. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice.

PubMed

Tomé, Stéphanie; Manley, Kevin; Simard, Jodie P; Clark, Greg W; Slean, Meghan M; Swami, Meera; Shelbourne, Peggy F; Tillier, Elisabeth R M; Monckton, Darren G; Messer, Anne; Pearson, Christopher E

2013-01-01

Expansions of trinucleotide CAG/CTG repeats in somatic tissues are thought to contribute to ongoing disease progression through an affected individual's life with Huntington's disease or myotonic dystrophy. Broad ranges of repeat instability arise between individuals with expanded repeats, suggesting the existence of modifiers of repeat instability. Mice with expanded CAG/CTG repeats show variable levels of instability depending upon mouse strain. However, to date the genetic modifiers underlying these differences have not been identified. We show that in liver and striatum the R6/1 Huntington's disease (HD) (CAG)∼100 transgene, when present in a congenic C57BL/6J (B6) background, incurred expansion-biased repeat mutations, whereas the repeat was stable in a congenic BALB/cByJ (CBy) background. Reciprocal congenic mice revealed the Msh3 gene as the determinant for the differences in repeat instability. Expansion bias was observed in congenic mice homozygous for the B6 Msh3 gene on a CBy background, while the CAG tract was stabilized in congenics homozygous for the CBy Msh3 gene on a B6 background. The CAG stabilization was as dramatic as genetic deficiency of Msh2. The B6 and CBy Msh3 genes had identical promoters but differed in coding regions and showed strikingly different protein levels. B6 MSH3 variant protein is highly expressed and associated with CAG expansions, while the CBy MSH3 variant protein is expressed at barely detectable levels, associating with CAG stability. The DHFR protein, which is divergently transcribed from a promoter shared by the Msh3 gene, did not show varied levels between mouse strains. Thus, naturally occurring MSH3 protein polymorphisms are modifiers of CAG repeat instability, likely through variable MSH3 protein stability. Since evidence supports that somatic CAG instability is a modifier and predictor of disease, our data are consistent with the hypothesis that variable levels of CAG instability associated with polymorphisms of DNA repair genes may have prognostic implications for various repeat-associated diseases.

MSH3 Polymorphisms and Protein Levels Affect CAG Repeat Instability in Huntington's Disease Mice

PubMed Central

Simard, Jodie P.; Clark, Greg W.; Slean, Meghan M.; Swami, Meera; Shelbourne, Peggy F.; Tillier, Elisabeth R. M.; Monckton, Darren G.; Messer, Anne; Pearson, Christopher E.

2013-01-01

Expansions of trinucleotide CAG/CTG repeats in somatic tissues are thought to contribute to ongoing disease progression through an affected individual's life with Huntington's disease or myotonic dystrophy. Broad ranges of repeat instability arise between individuals with expanded repeats, suggesting the existence of modifiers of repeat instability. Mice with expanded CAG/CTG repeats show variable levels of instability depending upon mouse strain. However, to date the genetic modifiers underlying these differences have not been identified. We show that in liver and striatum the R6/1 Huntington's disease (HD) (CAG)∼100 transgene, when present in a congenic C57BL/6J (B6) background, incurred expansion-biased repeat mutations, whereas the repeat was stable in a congenic BALB/cByJ (CBy) background. Reciprocal congenic mice revealed the Msh3 gene as the determinant for the differences in repeat instability. Expansion bias was observed in congenic mice homozygous for the B6 Msh3 gene on a CBy background, while the CAG tract was stabilized in congenics homozygous for the CBy Msh3 gene on a B6 background. The CAG stabilization was as dramatic as genetic deficiency of Msh2. The B6 and CBy Msh3 genes had identical promoters but differed in coding regions and showed strikingly different protein levels. B6 MSH3 variant protein is highly expressed and associated with CAG expansions, while the CBy MSH3 variant protein is expressed at barely detectable levels, associating with CAG stability. The DHFR protein, which is divergently transcribed from a promoter shared by the Msh3 gene, did not show varied levels between mouse strains. Thus, naturally occurring MSH3 protein polymorphisms are modifiers of CAG repeat instability, likely through variable MSH3 protein stability. Since evidence supports that somatic CAG instability is a modifier and predictor of disease, our data are consistent with the hypothesis that variable levels of CAG instability associated with polymorphisms of DNA repair genes may have prognostic implications for various repeat-associated diseases. PMID:23468640

Optical absorption in recycled waste plastic polyethylene

NASA Astrophysics Data System (ADS)

Aji, M. P.; Rahmawati, I.; Priyanto, A.; Karunawan, J.; Wati, A. L.; Aryani, N. P.; Susanto; Wibowo, E.; Sulhadi

2018-03-01

We investigated the optical properties of UV spectrum absorption in recycled waste plastic from polyethylene polymer type. Waste plastic polyethylene showed an optical spectrum absorption after it’s recycling process. Spectrum absorption is determined using spectrophotometer UV-Nir Ocean Optics type USB 4000. Recycling method has been processed using heating treatment around the melting point temperature of the polyethylene polymer that are 200°C, 220°C, 240°C, 260°C, and 280°C. In addition, the recycling process was carried out with time variations as well, which are 1h, 1.5h, 2h, and 2.5h. The result of this experiment shows that recycled waste plastic polyethylene has a spectrum absorption in the ∼ 340-550 nm wavelength range. The absorbance spectrum obtained from UV light which is absorbed in the orbital n → π* and the orbital π → π*. This process indicates the existence of electron transition phenomena. This mechanism is affected by the temperature and the heating time where the intensity of absorption increases and widens with the increase of temperature and heating time. Furthermore this study resulted that the higher temperature affected the enhancement of the band gap energy of waste plastic polyethylene. These results show that recycled waste plastic polyethylene has a huge potential to be absorber materials for solar cell.

Influence of Passive Joint Stiffness on Proprioceptive Acuity in Individuals With Functional Instability of the Ankle.

PubMed

Marinho, Hellen Veloso Rocha; Amaral, Giovanna Mendes; de Souza Moreira, Bruno; Araújo, Vanessa Lara; Souza, Thales Rezende; Ocarino, Juliana Melo; da Fonseca, Sérgio Teixeira

2017-12-01

Study Design Controlled laboratory study, cross-sectional. Background Deficits in ankle proprioceptive acuity have been reported in persons with functional instability of the ankle. Passive stiffness has been proposed as a possible mechanism underlying proprioceptive acuity. Objective To compare proprioceptive acuity and passive ankle stiffness in persons with and without functional ankle instability, and to assess the influence of passive joint stiffness on proprioceptive acuity in persons with functional ankle instability. Methods A sample of 18 subjects with and 18 without complaints of functional ankle instability following lateral ankle sprain participated. An isokinetic dynamometer was used to compare motion perception threshold, passive position sense, and passive ankle stiffness between groups. To evaluate the influence of passive stiffness on proprioceptive acuity, individuals in the lateral functional ankle instability group were divided into 2 subgroups: "high" and "low" passive ankle stiffness. Results The functional ankle instability group exhibited increased motion perception threshold when compared with the corresponding limb of the control group. Between-group differences were not found for passive position sense and passive ankle stiffness. Those in the functional ankle instability group with higher passive ankle stiffness had smaller motion perception thresholds than those with lower passive ankle stiffness. Conclusion Unlike motion perception threshold, passive position sense is not affected by the presence of functional ankle instability. Passive ankle stiffness appears to influence proprioceptive acuity in persons with functional ankle instability. J Orthop Sports Phys Ther 2017;47(12):899-905. Epub 7 Oct 2017. doi:10.2519/jospt.2017.7030.

Instabilities in rapid directional solidification under weak flow

NASA Astrophysics Data System (ADS)

Kowal, Katarzyna N.; Davis, Stephen H.; Voorhees, Peter W.

2017-12-01

We examine a rapidly solidifying binary alloy under directional solidification with nonequilibrium interfacial thermodynamics viz. the segregation coefficient and the liquidus slope are speed dependent and attachment-kinetic effects are present. Both of these effects alone give rise to (steady) cellular instabilities, mode S , and a pulsatile instability, mode P . We examine how weak imposed boundary-layer flow of magnitude |V | affects these instabilities. For small |V | , mode S becomes a traveling and the flow stabilizes (destabilizes) the interface for small (large) surface energies. For small |V | , mode P has a critical wave number that shifts from zero to nonzero giving spatial structure. The flow promotes this instability and the frequencies of the complex conjugate pairs each increase (decrease) with flow for large (small) wave numbers. These results are obtained by regular perturbation theory in powers of V far from the point where the neutral curves cross, but requires a modified expansion in powers of V1 /3 near the crossing. A uniform composite expansion is then obtained valid for all small |V | .

Genome instability: Linking ageing and brain degeneration.

PubMed

Barzilai, Ari; Schumacher, Björn; Shiloh, Yosef

2017-01-01

Ageing is a multifactorial process affected by cumulative physiological changes resulting from stochastic processes combined with genetic factors, which together alter metabolic homeostasis. Genetic variation in maintenance of genome stability is emerging as an important determinant of ageing pace. Genome instability is also closely associated with a broad spectrum of conditions involving brain degeneration. Similarities and differences can be found between ageing-associated decline of brain functionality and the detrimental effect of genome instability on brain functionality and development. This review discusses these similarities and differences and highlights cell classes whose role in these processes might have been underestimated-glia and microglia. Copyright © 2016. Published by Elsevier B.V.

Competing Turing and Faraday Instabilities in Longitudinally Modulated Passive Resonators.

PubMed

Copie, François; Conforti, Matteo; Kudlinski, Alexandre; Mussot, Arnaud; Trillo, Stefano

2016-04-08

We experimentally investigate the interplay of Turing (modulational) and Faraday (parametric) instabilities in a bistable passive nonlinear resonator. The Faraday branch is induced via parametric resonance owing to a periodic modulation of the resonator dispersion. We show that the bistable switching dynamics is dramatically affected by the competition between the two instability mechanisms, which dictates two completely novel scenarios. At low detunings from resonance, switching occurs between the stable stationary lower branch and the Faraday-unstable upper branch, whereas at high detunings we observe the crossover between the Turing and Faraday periodic structures. The results are well explained in terms of the universal Lugiato-Lefever model.

Production of Methane and Water from Crew Plastic Waste

NASA Technical Reports Server (NTRS)

Captain, Janine; Santiago, Eddie; Parrish, Clyde; Strayer, Richard F.; Garland, Jay L.

2008-01-01

Recycling is a technology that will be key to creating a self sustaining lunar outpost. The plastics used for food packaging provide a source of material that could be recycled to produce water and methane. The recycling of these plastics will require some additional resources that will affect the initial estimate of starting materials that will have to be transported from earth, mainly oxygen, energy and mass. These requirements will vary depending on the recycling conditions. The degredation products of these plastics will vary under different atmospheric conditions. An estimate of the the production rate of methane and water using typical ISRU processes along with the plastic recycling will be presented.

The crack effect on instability in a machine tool spindle with gas bearings

NASA Astrophysics Data System (ADS)

Huang, Bo-Wun

2005-09-01

Gas-bearing spindles are required for increased spindle speed in precise machining. Due to manufacturing flaws or cyclic loading, cracks frequently appear in a rotating spindle systems. Cracks markedly affect the dynamic characteristics of rotating machinery. Hence, in this study, high-speed spindles with gas bearings and the crack effect on the instability dynamics are considered. Most investigations on dynamic characteristics of the spindle system were confined to ball-bearing-type spindles. This work examines the dynamic instability in a cracked rotating spindle system with gas bearings. A round Euler-Bernoulli beam is used to approximate the spindle. The Hamilton principle is applied to derive the equation of motion for the spindle system. The effects of crack depth, rotation speed and provided air pressure on the dynamic instability of a rotating spindle system are studied

A transverse separate-spin-evolution streaming instability

NASA Astrophysics Data System (ADS)

Iqbal, Z.; Andreev, Pavel A.; Murtaza, G.

2018-05-01

By using the separate spin evolution quantum hydrodynamical model, the instability of transverse mode due to electron streaming in a partially spin polarized magnetized degenerate plasma is studied. The electron spin polarization gives birth to a new spin-dependent wave (i.e., separate spin evolution streaming driven ordinary wave) in the real wave spectrum. It is shown that the spin polarization and streaming speed significantly affect the frequency of this new mode. Analyzing growth rate, it is found that the electron spin effects reduce the growth rate and shift the threshold of instability as well as its termination point towards higher values. Additionally, how the other parameters like electron streaming and Fermi pressure influence the growth rate is also investigated. Current study can help towards better understanding of the existence of new waves and streaming instability in the astrophysical plasmas.

Transient High-Pressure Fuel Injection Processes

DTIC Science & Technology

2012-11-21

ADDRESSES U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 15. SUBJECT TERMS Fuel injection, hydrodynamic instability...nonlinear waves resulting from hydrodynamic instability form vortex structures that affect the shear layer near the interface. Pro- trusions (which are...to increase the length of the orifice channel; the orifice channel for case (a) is twice that of (b). The effects of cavitation and flow recirculation

How does variation in the environment and individual cognition explain the existence of consistent behavioral differences?

PubMed Central

Niemelä, Petri T; Vainikka, Anssi; Forsman, Jukka T; Loukola, Olli J; Kortet, Raine

2013-01-01

According to recent studies on animal personalities, the level of behavioral plasticity, which can be viewed as the slope of the behavioral reaction norm, varies among individuals, populations, and species. Still, it is conceptually unclear how the interaction between environmental variation and variation in animal cognition affect the evolution of behavioral plasticity and expression of animal personalities. Here, we (1) use literature to review how environmental variation and individual variation in cognition explain population and individual level expression of behavioral plasticity and (2) draw together empirically yet nontested, conceptual framework to clarify how these factors affect the evolution and expression of individually consistent behavior in nature. The framework is based on simple principles: first, information acquisition requires cognition that is inherently costly to build and maintain. Second, individual differences in animal cognition affect the differences in behavioral flexibility, i.e. the variance around the mean of the behavioral reaction norm, which defines plasticity. Third, along the lines of the evolution of cognition, we predict that environments with moderate variation favor behavioral flexibility. This occurs since in those environments costs of cognition are covered by being able to recognize and use information effectively. Similarly, nonflexible, stereotypic behaviors may be favored in environments that are either invariable or highly variable, since in those environments cognition does not give any benefits to cover the costs or cognition is not able to keep up with environmental change, respectively. If behavioral plasticity develops in response to increasing environmental variability, plasticity should dominate in environments that are moderately variable, and expression of animal personalities and behavioral syndromes may differ between environments. We give suggestions how to test our hypothesis and propose improvements to current behavioral testing protocols in the field of animal personality. PMID:23467316

The effects of a semi-rigid ankle brace on a simulated isolated subtalar joint instability.

PubMed

Choisne, Julie; Hoch, Matthew C; Bawab, Sebastian; Alexander, Ian; Ringleb, Stacie I

2013-12-01

Subtalar joint instability is hypothesized to occur after injuries to the calcaneofibular ligament (CFL) in isolation or in combination with the cervical and the talocalcaneal interosseous ligaments. A common treatment for hindfoot instability is the application of an ankle brace. However, the ability of an ankle brace to promote subtalar joint stability is not well established. We assessed the kinematics of the subtalar joint, ankle, and hindfoot in the presence of isolated subtalar instability, investigated the effect of bracing in a CFL deficient foot and with a total rupture of the intrinsic ligaments, and evaluated how maximum inversion range of motion is affected by the position of the ankle in the sagittal plane. Kinematics from nine cadaveric feet were collected with the foot placed in neutral, dorsiflexion, and plantar flexion. Motion was applied with and without a brace on an intact foot and after sequentially sectioning the CFL and the intrinsic ligaments. Isolated CFL sectioning increased ankle joint inversion, while sectioning the CFL and intrinsic ligaments affected subtalar joint stability. The brace limited inversion at the subtalar and ankle joints. Additionally, examining the foot in dorsiflexion reduced ankle and subtalar joint motion. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

Evaluation of functional outcomes and complications following modified Latarjet reconstruction in athletes with anterior shoulder instability

PubMed Central

van der Watt, Christelle; de Beer, Joe F

2015-01-01

Background The optimal management of anterior shoulder instability in athletes continues to be a challenge. The present study aimed to evaluate the functional outcomes of athletes with anterior shoulder instability following modified Latarjet reconstruction through assessing the timing of return to sport and complications. Methods Retrospective assessment was performed of athletes (n = 56) who presented with recurrent anterior shoulder instability and were treated with modified congruent arc Latarjet reconstruction over a 1-year period. Rugby union was the predominant sport performed. Pre-operative instability severity index scores were assessed. Postoperative complications were recorded as was the time taken for the athlete to return to sport. Results Arthroscopic evaluation revealed that 86% of patients had associated bony lesions affecting the glenohumeral joint. The overall complication rate relating to the Latarjet reconstruction was 7%. No episodes of recurrent shoulder instability were noted. Of the patients, 89% returned to competitive sport at the same level as that prior to surgery. The mean time post surgery to returning to full training was 3.2 months. Conclusions The modified congruent arc Latarjet procedure facilitates early rehabilitation and return to sport. These results support our systematic management protocol of performing modified Latarjet surgery in contact sport athletes with recurrent anterior instability. PMID:27582973

Superradiant instabilities of rotating black branes and strings

NASA Astrophysics Data System (ADS)

Cardoso, Vitor; Yoshida, Shijun

2005-07-01

Black branes and strings are generally unstable against a certain sector of gravitational perturbations. This is known as the Gregory-Laflamme instability. It has been recently argued [1], [2] that there exists another general instability affecting many rotating extended black objects. This instability is in a sense universal, in that it is triggered by any massless field, and not just gravitational perturbations. Here we investigate this novel mechanism in detail. For this instability to work, two ingredients are necessary: (i) an ergo-region, which gives rise to superradiant amplification of waves, and (ii) ``bound'' states in the effective potential governing the evolution of the particular mode under study. We show that the black brane Kerr4×Rp is unstable against this mechanism, and we present numerical results for instability timescales for this case. On the other hand, and quite surprisingly, black branes of the form Kerrd×Rp are all stable against this mechanism for d > 4. This is quite an unexpected result, and it stems from the fact that there are no stable circular orbits in higher dimensional black hole spacetimes, or in a wave picture, that there are no bound states in the effective potential. We also show that it is quite easy to simulate this instability in the laboratory with acoustic black branes.

Neuronal plasticity and thalamocortical sleep and waking oscillations

PubMed Central

Timofeev, Igor

2011-01-01

Throughout life, thalamocortical (TC) network alternates between activated states (wake or rapid eye movement sleep) and slow oscillatory state dominating slow-wave sleep. The patterns of neuronal firing are different during these distinct states. I propose that due to relatively regular firing, the activated states preset some steady state synaptic plasticity and that the silent periods of slow-wave sleep contribute to a release from this steady state synaptic plasticity. In this respect, I discuss how states of vigilance affect short-, mid-, and long-term synaptic plasticity, intrinsic neuronal plasticity, as well as homeostatic plasticity. Finally, I suggest that slow oscillation is intrinsic property of cortical network and brain homeostatic mechanisms are tuned to use all forms of plasticity to bring cortical network to the state of slow oscillation. However, prolonged and profound shift from this homeostatic balance could lead to development of paroxysmal hyperexcitability and seizures as in the case of brain trauma. PMID:21854960

Durable antistatic coating for polymethylmethacrylate

NASA Technical Reports Server (NTRS)

Hadek, V.; Somoano, R. B.; Rembaum, A. (Inventor)

1977-01-01

A durable antistatic coating is achieved on polymethylmethacrylate plastic without affecting its optical clarity by applying to the surface of the plastic a low molecular weight solvent having a high electron affinity and a high dipole moment, such as acentonitrile or nitromethane alone or in the presence of photopolymerizable monomer. The treated polymethylmethacrylate plastic dissipates most of the induced electrostatic charge and retains its optical clarity. The antistatic behavior persists after washing, rubbing and vacuum treatment.

Functional outcomes following lesions in visual cortex: Implications for plasticity of high-level vision.

PubMed

Liu, Tina T; Behrmann, Marlene

2017-10-01

Understanding the nature and extent of neural plasticity in humans remains a key challenge for neuroscience. Importantly, however, a precise characterization of plasticity and its underlying mechanism has the potential to enable new approaches for enhancing reorganization of cortical function. Investigations of the impairment and subsequent recovery of cognitive and perceptual functions following early-onset cortical lesions in humans provide a unique opportunity to elucidate how the brain changes, adapts, and reorganizes. Specifically, here, we focus on restitution of visual function, and we review the findings on plasticity and re-organization of the ventral occipital temporal cortex (VOTC) in published reports of 46 patients with a lesion to or resection of the visual cortex early in life. Findings reveal that a lesion to the VOTC results in a deficit that affects the visual recognition of more than one category of stimuli (faces, objects and words). In addition, the majority of pediatric patients show limited recovery over time, especially those in whom deficits in low-level vision also persist. Last, given that neither the equipotentiality nor the modularity view on plasticity was clearly supported, we suggest some intermediate possibilities in which some plasticity may be evident but that this might depend on the area that was affected, its maturational trajectory as well as its structural and functional connectivity constraints. Finally, we offer suggestions for future research that can elucidate plasticity further. Copyright © 2017 Elsevier Ltd. All rights reserved.

Morphological plasticity reduces the effect of poor developmental conditions on fledging age in mourning doves

PubMed Central

Miller, David A.

2010-01-01

Developmental plasticity can be integral in adapting organisms to the environment experienced during growth. Adaptive plastic responses may be especially important in prioritizing development in response to stress during ontogeny. To evaluate this, I examined how developmental conditions for mourning doves related to early growth and how this affected fledging age, an important life-history transition for birds. The life history of mourning doves is consistent with strong selective pressure to minimize fledging age. Therefore, I predicted that in the face of nutritional stress associated with experimental brood-size increases, young would prioritize growth to structures that promote early fledging to reduce the effect of slowed overall growth on fledging age. Increasing brood size slowed overall structural growth of nestlings and affected the relative allocation of growth among different body parts. Total wing area was the best predictor of fledging age and individuals from larger broods had larger wings relative to overall body size. Although nestlings from larger broods fledged at later ages owing to slower overall growth, prioritization of wing growth reduced this effect by an estimated 1.6 days relative to the delay if plasticity among body parts had not occurred. This was an 11 per cent reduction in the predicted developmental time it took to reach this important life-history transition. Results demonstrate that preferential allocation to wing growth can affect the timing of this life-history transition and that morphological plasticity during development can have adaptive near-term effects during avian development. PMID:20129984

Frictional behaviour and evolution of rough faults in limestone

NASA Astrophysics Data System (ADS)

Harbord, C. W. A.; Nielsen, S. B.; De Paola, N.; Holdsworth, R.

2017-12-01

Fault roughness is an important parameter which influences the frictional behaviour of seismically active faults, in particular the nucleation stage of earthquakes. Here we investigate frictional sliding and stability of roughened micritic limestone surfaces from the seismogenic layer in Northern-Central Apennines of Italy. Samples are roughened using #60, #220 and #400 grit and deformed in a direct shear configuration at conditions typical of the shallow upper crust (15-60 MPa normal stress). We perform velocity steps between 0.01-1 μm s-1 to obtain rate-and-state friction parameters a, b and L. At low normal stress conditions (30 MPa) and at displacements of <3-4mm there is a clear 2 state evolution of friction with two state parameters, b1 and b2, and accompanying critical slip distances L1 and L2 for all roughnesses. In some cases, on smooth faults (#400 grit), the short term evolution leads to silent slow instability which is modulated by the second state evolution. With increasing slip displacement (>2-4 mm) friction can be modelled with a single state parameter, b, as the short frictional evolution disappears. The longer term state evolution, b2, gives negative values of b, reminiscent of plastic creep experiments at high temperature, reaching a steady state at 3-4 mm displacement. Microstructural observations reveal shiny surfaces decorated by nanometric gouge particles with variable porosity. When normal stress is increased, rough faults (#60 grit) revert to a single state evolution with positive values of b, whilst smoother faults (#220 & #400 grit) retain a two state evolution with negative b2 values. These observations suggest that on carbonate hosted faults sliding may be controlled by plastic processes which can lead to slow stick-slip instability, which may be supressed by frictional wear and accompanying gouge build-up.

Hot-spot mix in ignition-scale implosions on the NIF [Hot-spot mix in ignition-scale implosions on the National Ignition Facility (NIF)

DOE PAGES

Regan, S. P.; Epstein, R.; Hammel, B. A.; ...

2012-03-30

Ignition of an inertial confinement fusion (ICF) target depends on the formation of a central hot spot with sufficient temperature and areal density. Radiative and conductive losses from the hot spot can be enhanced by hydrodynamic instabilities. The concentric spherical layers of current National Ignition Facility (NIF) ignition targets consist of a plastic ablator surrounding 2 a thin shell of cryogenic thermonuclear fuel (i.e., hydrogen isotopes), with fuel vapor filling the interior volume. The Rev. 5 ablator is doped with Ge to minimize preheat of the ablator closest to the DT ice caused by Au M-band emission from the hohlraummore » x-ray drive. Richtmyer–Meshkov and Rayleigh–Taylor hydrodynamic instabilities seeded by high-mode (50 < t < 200) ablator-surface perturbations can cause Ge-doped ablator to mix into the interior of the shell at the end of the acceleration phase. As the shell decelerates, it compresses the fuel vapor, forming a hot spot. K-shell line emission from the ionized Ge that has penetrated into the hot spot provides an experimental signature of hot-spot mix. The Ge emission from tritium–hydrogen–deuterium (THD) and DT cryogenic targets and gas-filled plastic shell capsules, which replace the THD layer with a massequivalent CH layer, was examined. The inferred amount of hot-spot mix mass, estimated from the Ge K-shell line brightness using a detailed atomic physics code, is typically below the 75 ng allowance for hot-spot mix. Furthermore, predictions of a simple mix model, based on linear growth of the measured surface-mass modulations, are consistent with the experimental results.« less

Hot-spot mix in ignition-scale implosions on the NIF [Hot-spot mix in ignition-scale implosions on the National Ignition Facility (NIF)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Regan, S. P.; Epstein, R.; Hammel, B. A.

Ignition of an inertial confinement fusion (ICF) target depends on the formation of a central hot spot with sufficient temperature and areal density. Radiative and conductive losses from the hot spot can be enhanced by hydrodynamic instabilities. The concentric spherical layers of current National Ignition Facility (NIF) ignition targets consist of a plastic ablator surrounding 2 a thin shell of cryogenic thermonuclear fuel (i.e., hydrogen isotopes), with fuel vapor filling the interior volume. The Rev. 5 ablator is doped with Ge to minimize preheat of the ablator closest to the DT ice caused by Au M-band emission from the hohlraummore » x-ray drive. Richtmyer–Meshkov and Rayleigh–Taylor hydrodynamic instabilities seeded by high-mode (50 < t < 200) ablator-surface perturbations can cause Ge-doped ablator to mix into the interior of the shell at the end of the acceleration phase. As the shell decelerates, it compresses the fuel vapor, forming a hot spot. K-shell line emission from the ionized Ge that has penetrated into the hot spot provides an experimental signature of hot-spot mix. The Ge emission from tritium–hydrogen–deuterium (THD) and DT cryogenic targets and gas-filled plastic shell capsules, which replace the THD layer with a massequivalent CH layer, was examined. The inferred amount of hot-spot mix mass, estimated from the Ge K-shell line brightness using a detailed atomic physics code, is typically below the 75 ng allowance for hot-spot mix. Furthermore, predictions of a simple mix model, based on linear growth of the measured surface-mass modulations, are consistent with the experimental results.« less

Prevalence of Suicidal Ideation and Its Association with Positive Affect in Working Women: A Day Reconstruction Study

PubMed Central

Tian, Lili; Yang, Ying; Yang, Huijing; Huebner, E. Scott

2017-01-01

The suicide rate for females in China is the second highest worldwide, and China is the only country in the world in which the rate of suicides is higher for women than men. Affective instability has been shown to be a strong predictor of suicidal ideation, particularly among women. However, prior research has mainly focused on the impact of women's negative affect on suicidal ideation, ignoring the influence of positive affect on suicidal ideation. Studies have revealed that hopelessness, which is 1.3 times more important than depression for explaining suicidal ideation, is driven more by low levels of positive affect than by high levels of negative affect. Although positive affect has also been found to be related to suicidal ideation, and it demonstrates independent, beneficial effects on mental health, much remains to be learned about the association between positive affective instability and suicidal ideation. Therefore, we investigated the prevalence of suicidal ideation among Chinese working women and explored the differences between working women with and without suicidal ideation in the intensity and daily variability of positive affect. A total of 222 young working women of ages 22–36 years (M = 27.64, SD = 3.73) were recruited from a free weekend psychology lecture. The women subsequently completed a daily diary Day Reconstruction Method (DRM) as well as a suicidal ideation questionnaire. We used hierarchical linear modeling (HLM) to analyze the data, and the results showed that: (1) 10.81% of participates reported suicidal ideation, the intensity of positive affect (happiness, warmth/friendliness, interest and relaxation/calmness) was significantly lower for women with suicidal ideation compared to women without suicidal ideation; (2) differing diurnal patterns of positive emotions were observed between women with and without suicidal ideation; women with suicidal ideation demonstrated a significantly lower trend of growth and a higher volatility in happiness, warmth/friendliness, relaxation/calmness. Given that lower intensity of positive affect and greater affective instability significantly predicted suicidal ideation in Chinese women, researchers should pay more attention to the role of positive affect in female suicide prevention research and intervention efforts in the future. PMID:28377731

Prevalence of Suicidal Ideation and Its Association with Positive Affect in Working Women: A Day Reconstruction Study.

PubMed

Tian, Lili; Yang, Ying; Yang, Huijing; Huebner, E Scott

2017-01-01

The suicide rate for females in China is the second highest worldwide, and China is the only country in the world in which the rate of suicides is higher for women than men. Affective instability has been shown to be a strong predictor of suicidal ideation, particularly among women. However, prior research has mainly focused on the impact of women's negative affect on suicidal ideation, ignoring the influence of positive affect on suicidal ideation. Studies have revealed that hopelessness, which is 1.3 times more important than depression for explaining suicidal ideation, is driven more by low levels of positive affect than by high levels of negative affect. Although positive affect has also been found to be related to suicidal ideation, and it demonstrates independent, beneficial effects on mental health, much remains to be learned about the association between positive affective instability and suicidal ideation. Therefore, we investigated the prevalence of suicidal ideation among Chinese working women and explored the differences between working women with and without suicidal ideation in the intensity and daily variability of positive affect. A total of 222 young working women of ages 22-36 years ( M = 27.64, SD = 3.73) were recruited from a free weekend psychology lecture. The women subsequently completed a daily diary Day Reconstruction Method (DRM) as well as a suicidal ideation questionnaire. We used hierarchical linear modeling (HLM) to analyze the data, and the results showed that: (1) 10.81% of participates reported suicidal ideation, the intensity of positive affect (happiness, warmth/friendliness, interest and relaxation/calmness) was significantly lower for women with suicidal ideation compared to women without suicidal ideation; (2) differing diurnal patterns of positive emotions were observed between women with and without suicidal ideation; women with suicidal ideation demonstrated a significantly lower trend of growth and a higher volatility in happiness, warmth/friendliness, relaxation/calmness. Given that lower intensity of positive affect and greater affective instability significantly predicted suicidal ideation in Chinese women, researchers should pay more attention to the role of positive affect in female suicide prevention research and intervention efforts in the future.

Structural and Functional Plasticity in the Maternal Brain Circuitry

ERIC Educational Resources Information Center

Pereira, Mariana

2016-01-01

Parenting recruits a distributed network of brain structures (and neuromodulators) that coordinates caregiving responses attuned to the young's affect, needs, and developmental stage. Many of these structures and connections undergo significant structural and functional plasticity, mediated by the interplay between maternal hormones and social…

Genetics, the facial plastic and reconstructive surgeon, and the future.

PubMed

Seidman, M D

2001-01-01

Predicting the future is a daunting task that is typically reserved for visionaries or tarot card readers. Nonetheless, the challenge is set, and this brief essay will predict how genetics and molecular biology may affect diseases in facial plastic and reconstructive surgery.

Using Expert Elicitation to Estimate the Impacts of Plastic Pollution on Marine Wildlife

NASA Astrophysics Data System (ADS)

Mallos, N. J.; Wilcox, C.; Leonard, G. H.; Rodriquez, A. G.; Hardesty, B. D.

2016-02-01

With the rapid increase in global plastics production and the resulting large volume of litter that enters the marine environment, determining the consequences of this debris on marine fauna and ocean health has now become a critical environmental priority, particularly for threatened and endangered species. However, there are limited data about the impacts on debris on marine species from which to draw conclusions about the population consequences of anthropogenic debris. To address this knowledge gap, information was elicited from experts on the ecological threat of entanglement, ingestion and chemical contamination for three major marine taxa: seabirds, sea turtles and marine mammals. The threat assessment focused on the most common types of litter that are found along the world's coastlines, based on data gathered during three decades of international coastal clean-up efforts. Fishing related gear, balloons and plastic bags were estimated to pose the greatest entanglement risk to marine fauna. In contrast, experts identified a broader suite of items of concern for ingestion, with plastic bags and plastic utensils ranked as the greatest threats. Entanglement and ingestion affected a similar range of taxa, although entanglement was slightly worse as it is more likely to be lethal. Contamination was scored the lowest in terms of its impact, affecting a smaller portion of the taxa and being rated as having solely non-lethal impacts. Research designed to better understand and quantify the impacts of chemical contamination on marine fauna at individual, population and species levels should be a priority for conservation biologists. This work points towards a number of opportunities for both policy-based and consumer-driven changes in plastics use that could have demonstrable affects for a range of taxa that are ecologically important and serve as indicators of marine ecosystem health. Based on threat rankings, entanglement and ingestion should be a similar priority for management action, as experts ranked them nearly identically in terms of expected population impacts. Fishing gear, plastic bags, and plastic utensils were all ranked as having substantial impacts on more than half of all three marine taxa, and should be priorities for management action.

Plastic debris in Mediterranean seabirds.

PubMed

Codina-García, Marina; Militão, Teresa; Moreno, Javier; González-Solís, Jacob

2013-12-15

Plastic debris is often ingested by marine predators and can cause health disorders and even death. We present the first assessment of plastic ingestion in Mediterranean seabirds. We quantified and measured plastics accumulated in the stomach of 171 birds from 9 species accidentally caught by longliners in the western Mediterranean from 2003 to 2010. Cory's shearwaters (Calonectris diomedea) showed the highest occurrence (94%) and large numbers of small plastic particles per affected bird (on average N = 15.3 ± 24.4 plastics and mass = 23.4 ± 49.6 mg), followed by Yelkouan shearwaters (Puffinus yelkouan, 70%, N = 7.0 ± 7.9, 42.1 ± 100.0 mg), Balearic shearwaters (Puffinus mauretanicus, 70%, N = 3.6 ± 2.9, 5.5 ± 9.7 mg) and the rest of species (below 33%, N = 2.7, 113.6 ± 128.4 mg). Plastic characteristics did not differ between sexes and were not related to the physical condition of the birds. Our results point out the three endemic and threatened shearwater species as being particularly exposed to plastic accumulation.

Faraday instability on patterned surfaces

NASA Astrophysics Data System (ADS)

Feng, Jie; Rubinstein, Gregory; Jacobi, Ian; Stone, Howard

2013-11-01

We show how micro-scale surface patterning can be used to control the onset of the Faraday instability in thin liquid films. It is well known that when a liquid film on a planar substrate is subject to sufficient vibrational accelerations, the free surface destabilizes, exhibiting a family of non-linear standing waves. This instability remains a canonical problem in the study of spontaneous pattern formation, but also has practical uses. For example, the surface waves induced by the Faraday instability have been studied as a means of enhanced damping for mechanical vibrations (Genevaux et al. 2009). Also the streaming within the unstable layer has been used as a method for distributing heterogeneous cell cultures on growth medium (Takagi et al. 2002). In each of these applications, the roughness of the substrate significantly affects the unstable flow field. We consider the effect of patterned substrates on the onset and behavior of the Faraday instability over a range of pattern geometries and feature heights where the liquid layer is thicker than the pattern height. Also, we describe a physical model for the influence of patterned roughness on the destabilization of a liquid layer in order to improve the design of practical systems which exploit the Faraday instability.

On numerical instabilities of Godunov-type schemes for strong shocks

NASA Astrophysics Data System (ADS)

Xie, Wenjia; Li, Wei; Li, Hua; Tian, Zhengyu; Pan, Sha

2017-12-01

It is well known that low diffusion Riemann solvers with minimal smearing on contact and shear waves are vulnerable to shock instability problems, including the carbuncle phenomenon. In the present study, we concentrate on exploring where the instability grows out and how the dissipation inherent in Riemann solvers affects the unstable behaviors. With the help of numerical experiments and a linearized analysis method, it has been found that the shock instability is strongly related to the unstable modes of intermediate states inside the shock structure. The consistency of mass flux across the normal shock is needed for a Riemann solver to capture strong shocks stably. The famous carbuncle phenomenon is interpreted as the consequence of the inconsistency of mass flux across the normal shock for a low diffusion Riemann solver. Based on the results of numerical experiments and the linearized analysis, a robust Godunov-type scheme with a simple cure for the shock instability is suggested. With only the dissipation corresponding to shear waves introduced in the vicinity of strong shocks, the instability problem is circumvented. Numerical results of several carefully chosen strong shock wave problems are investigated to demonstrate the robustness of the proposed scheme.

Modeling collective behavior of dislocations in crystalline materials

NASA Astrophysics Data System (ADS)

Varadhan, Satya N.

Elastic interaction of dislocations leads to collective behavior and determines plastic response at the mesoscale. Notable characteristics of mesoscale plasticity include the formation of dislocation patterns, propagative instability phenomena due to strain aging such as the Luders and Portevin-Le Chatelier effects, and size-dependence of low stress. This work presents a unified approach to modeling collective behavior based on mesoscale field dislocation mechanics and crystal plasticity, using constitutive models with physical basis. Successful application is made to: compression of a bicrystal, where "smaller is stronger"---the flow stress increases as the specimen size is reduced; torsional creep of ice single crystals, where the plastic strain rate increases with time under constant applied torque; strain aging in a single crystal alloy, where the transition from homogeneous deformation to intermittent bands to continuous band is captured as the applied deformation rate is increased. A part of this work deals with the kinematics of dislocation density evolution. An explicit Galerkin/least-squares formulation is introduced for the quasilinear evolution equation, which leads to a symmetric and well-conditioned system of equations with constant coefficients, making it attractive for large-scale problems. It is shown that the evolution equation simplifies to the Hamilton-Jacobi equations governing geometric optics and level set methods in the following physical contexts: annihilation of dislocations, expansion of a polygonal dislocation loop and operation of a Frank-Read source. The weak solutions to these equations are not unique, and the numerical method is able to capture solutions corresponding to shock as well as expansion fans.

Does handwriting on a tablet screen affect students' graphomotor execution? A comparison between Grades Two and Nine.

PubMed

Alamargot, Denis; Morin, Marie-France

2015-12-01

We sought to ascertain how handwriting with a plastic-tipped pen on the screen of a digital tablet affects graphomotor execution in students, compared with handwriting on paper with a ballpoint pen. We predicted that the modification to propriokinesthetic feedback induced by the screen/plastic tip combination would differently disturb younger and older students, who rely on perceptual feedback either to form letters (former) or to adjust movement execution (latter). Twenty-eight students from Grades Two and Nine were asked to handwrite the alphabet and their names and surnames under the two conditions. Kinematics were recorded using the tablet, controlled by Eye and Pen software. Results showed that handwriting on the tablet surface with a plastic-tipped pen primarily affected pen pauses in the second graders and pen movements in the ninth graders, suggesting a disturbance in segment trajectory calculation in the younger participants and reduced control of muscular adjustment in the older children. Copyright © 2015 Elsevier B.V. All rights reserved.

Worldwide Emerging Environmental Issues Affecting the U.S. Military. December 2007 Report

DTIC Science & Technology

2007-12-01

was developed by researchers of Cornell University. The plastic is a modified form of polyhydroxybutyrate ( PHB ), a promising biodegradable plastic...produced from bacteria. The use of PHB has been limited because of its brittleness and unpredictable biodegradation rates. The new material, which is

40 CFR 60.720 - Applicability and designation of affected facility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Industrial Surface Coating: Surface Coating of Plastic Parts for Business Machines § 60.720... in which plastic parts for use in the manufacture of business machines receive prime coats, color...

49 CFR 178.609 - Test requirements for packagings for infectious substances.

Code of Federal Regulations, 2010 CFR

2010-10-01

... paragraph (c), which, for test purposes, categorizes packagings according to their material characteristics... performance may be rapidly affected by moisture; plastics that may embrittle at low temperature; and other... the appropriate test. Table I—Tests Required Material of Outer packaging Fiberboard Plastics Other...

Plastic Accumulation in the Mediterranean Sea

PubMed Central

Cózar, Andrés; Sanz-Martín, Marina; Martí, Elisa; González-Gordillo, J. Ignacio; Ubeda, Bárbara; Gálvez, José Á.; Irigoien, Xabier; Duarte, Carlos M.

2015-01-01

Concentrations of floating plastic were measured throughout the Mediterranean Sea to assess whether this basin can be regarded as a great accumulation region of plastic debris. We found that the average density of plastic (1 item per 4 m2), as well as its frequency of occurrence (100% of the sites sampled), are comparable to the accumulation zones described for the five subtropical ocean gyres. Plastic debris in the Mediterranean surface waters was dominated by millimeter-sized fragments, but showed a higher proportion of large plastic objects than that present in oceanic gyres, reflecting the closer connection with pollution sources. The accumulation of floating plastic in the Mediterranean Sea (between 1,000 and 3,000 tons) is likely related to the high human pressure together with the hydrodynamics of this semi-enclosed basin, with outflow mainly occurring through a deep water layer. Given the biological richness and concentration of economic activities in the Mediterranean Sea, the affects of plastic pollution on marine and human life are expected to be particularly frequent in this plastic accumulation region. PMID:25831129

Endocannabinoid signaling is required for development and critical period plasticity of the whisker map in somatosensory cortex

PubMed Central

Li, Lu; Bender, Kevin J.; Drew, Patrick J.; Jadhav, Shantanu P.; Sylwestrak, Emily; Feldman, Daniel E.

2009-01-01

Summary Type 1 cannabinoid (CB1) receptors mediate widespread synaptic plasticity, but how this contributes to systems-level plasticity and development in vivo is unclear. We tested whether CB1 signaling is required for development and plasticity of the whisker map in rat somatosensory cortex. Treatment with the CB1 antagonist AM251 during an early critical period for layer (L) 2/3 development (beginning postnatal day [P] 12–16) disrupted whisker map development, leading to inappropriate whisker tuning in L2/3 column edges and a blurred map. Early AM251 treatment also prevented experience-dependent plasticity in L2/3, including deprivation-induced synapse weakening and weakening of deprived whisker responses. CB1 blockade after P25 did not disrupt map development or plasticity. AM251 had no acute effect on sensory-evoked spiking, and only modestly affected field potentials, suggesting that plasticity effects were not secondary to gross activity changes. These findings implicate CB1-dependent plasticity in systems-level development and early postnatal plasticity of the whisker map. PMID:19945395

Instability analysis and free volume simulations of shear band directions and arrangements in notched metallic glasses

DOE PAGES

Li, Weidong; Gao, Yanfei; Bei, Hongbin

2016-10-10

As a commonly used method to enhance the ductility in bulk metallic glasses (BMGs), the introduction of geometric constraints blocks and confines the propagation of the shear bands, reduces the degree of plastic strain on each shear band so that the catastrophic failure is prevented or delayed, and promotes the formation of multiple shear bands. The clustering of multiple shear bands near notches is often interpreted as the reason for improved ductility. Experimental works on the shear band arrangements in notched metallic glasses have been extensively carried out, but a systematic theoretical study is lacking. Using instability theory that predictsmore » the onset of strain localization and the free-volume- based nite element simulations that predict the evolution of shear bands, this work reveals various categories of shear band arrangements in double edge notched BMGs with respect to the mode mixity of the applied stress fields. In conclusion, a mechanistic explanation is thus provided to a number of related experiments and especially the correlation between various types of shear bands and the stress state.« less

Elastic energy distribution in bi-material lithosphere: implications for shear zone formation

NASA Astrophysics Data System (ADS)

So, B.; Yuen, D. A.

2013-12-01

Shear instability in the lithosphere can cause mechanical rupturing such as slab detachment and deep focus earthquake. Recent studies reported that bi-material interface, which refers to sharp elastic modulus contrast, plays an important role in triggering the instability [So and Yuen et al., 2012, GJI]. In present study, we performed two-dimensional numerical simulations to investigate the distribution of thermal-mechanical energy within the bi-material lithosphere. Under the far-field constant compression exerted on the domain, a larger elastic energy is accumulated into the compliant part than stiff medium. For instance, the compliant part has two times greater elastic energy density than surrounding stiff part, when the elastic modulus contrast between two different parts is five. Although these elastic energies in both parts are conversed into thermal energies after plastic yielding, denser elastic energy in the compliant is released more efficiently. This leads to efficient strength weakening and the subsequent ductile shear zone in the compliant part. We propose that strong shear heating occurs in lithosphere with the bi-material interface due to locally non-uniform distribution of the energy around the interface.

On the role of particle cracking in flow and fracture of metal matrix composites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brockenbrough, J.R.; Zok, F.W.

1995-01-01

The flow response of particle-reinforced metal matrix composites is studied using finite element methods. Unit cells containing either intact or cracked particles in a power law hardening matrix are used to determine the corresponding asymptotic flow strengths. The effects of the hardening exponent and the elastic mismatch between the particles and the matrix on the flow response are examined. For comparison, the flow response of power law hardening solids containing penny-shaped cracks is also evaluated. The latter results are found to be in reasonable agreement with those corresponding to composites that contain low volume fractions of cracked particles. The asymptoticmore » results are used to develop a one-dimensional constitutive law for composites which undergo progressive damage during tensile straining. This law is used to evaluate the strain at the onset of plastic instability. It is proposed that the instability strain be used as a measure of tensile ductility when the particle content is low and the particles are uniformly distributed through the matrix.« less

Characterization of long-scale-length plasmas produced from plastic foam targets for laser plasma instability (LPI) research

NASA Astrophysics Data System (ADS)

Oh, Jaechul; Weaver, J. L.; Serlin, V.; Obenschain, S. P.

2017-10-01

We report on an experimental effort to produce plasmas with long scale lengths for the study of parametric instabilities, such as two plasmon decay (TPD) and stimulated Raman scattering (SRS), under conditions relevant to fusion plasma. In the current experiment, plasmas are formed from low density (10-100 mg/cc) CH foam targets irradiated by Nike krypton fluoride laser pulses (λ = 248 nm, 1 nsec FWHM) with energies up to 1 kJ. This experiment is conducted with two primary diagnostics: the grid image refractometer (Nike-GIR) to measure electron density and temperature profiles of the coronas, and time-resolved spectrometers with absolute intensity calibration to examine scattered light features of TPD or SRS. Nike-GIR was recently upgraded with a 5th harmonic probe laser (λ = 213 nm) to access plasma regions near quarter critical density of 248 nm light (4.5 ×1021 cm-3). The results will be discussed with data obtained from 120 μm scale-length plasmas created on solid CH targets in previous LPI experiments at Nike. Work supported by DoE/NNSA.

Topographic-driven instabilities in terrestrial bodies

NASA Astrophysics Data System (ADS)

Vantieghem, S.; Cebron, D.; Herreman, W.; Lacaze, L.

2013-12-01

Models of internal planetary fluid layers (core flows, subsurface oceans) commonly assume that these fluid envelopes have a spherical shape. This approximation however entails a serious restriction from the fluid dynamics point of view. Indeed, in the presence of mechanical forcings (precession, libration, nutation or tides) due to gravitational interaction with orbiting partners, boundary topography (e.g. of the core-mantle boundary) may excite flow instabilities and space-filling turbulence. These phenomena may affect heat transport and dissipation at the main order. Here, we focus on instabilities driven by longitudinal libration. Using a suite of theoretical tools and numerical simulations, we are able to discern a parameter range for which instability may be excited. We thereby consider deformations of different azimuthal order. This study gives the first numerical evidence of the tripolar instability. Furthermore, we explore the non-linear regime and investigate the amplitude as well as the dissipation of the saturated instability. Indeed, these two quantities control the torques on the solid layers and the thermal transport. Furthermore, based on this results, we address the issue of magnetic field generation associated with these flows (by induction or by dynamo process). This instability mechanism applies to both synchronized as non-synchronized bodies. As such, our results show that a tripolar instability might be present in various terrestrial bodies (Early Moon, Gallilean moons, asteroids, etc.), where it could participate in dynamo action. Simulation of a libration-driven tripolar instability in a deformed spherical fluid layer: snapshot of the velocity magnitude, where a complex 3D flow pattern is established.

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning.

PubMed

de Hoz, Livia; Gierej, Dorota; Lioudyno, Victoria; Jaworski, Jacek; Blazejczyk, Magda; Cruces-Solís, Hugo; Beroun, Anna; Lebitko, Tomasz; Nikolaev, Tomasz; Knapska, Ewelina; Nelken, Israel; Kaczmarek, Leszek

2018-05-01

The behavioral changes that comprise operant learning are associated with plasticity in early sensory cortices as well as with modulation of gene expression, but the connection between the behavioral, electrophysiological, and molecular changes is only partially understood. We specifically manipulated c-Fos expression, a hallmark of learning-induced synaptic plasticity, in auditory cortex of adult mice using a novel approach based on RNA interference. Locally blocking c-Fos expression caused a specific behavioral deficit in a sound discrimination task, in parallel with decreased cortical experience-dependent plasticity, without affecting baseline excitability or basic auditory processing. Thus, c-Fos-dependent experience-dependent cortical plasticity is necessary for frequency discrimination in an operant behavioral task. Our results connect behavioral, molecular and physiological changes and demonstrate a role of c-Fos in experience-dependent plasticity and learning.

Cryogenic High-Pressure Shear-Coaxial Jets Exposed to Transverse Acoustic Forcing

DTIC Science & Technology

2011-12-13

formation. Detailed studies on the development and growth of natural instabilities in a single circular jet6 or a single circular jet with coflow7...reveal two of the most significant natural modes of instability: the axisymmetric and the first azimuthal or helical modes. These modes have comparable... natural as well as externally imposed flow conditions such as pressure or velocity perturbations, affecting their development, may be used to assess

Spontaneous mutation rate is a plastic trait associated with population density across domains of life.

PubMed

Krašovec, Rok; Richards, Huw; Gifford, Danna R; Hatcher, Charlie; Faulkner, Katy J; Belavkin, Roman V; Channon, Alastair; Aston, Elizabeth; McBain, Andrew J; Knight, Christopher G

2017-08-01

Rates of random, spontaneous mutation can vary plastically, dependent upon the environment. Such plasticity affects evolutionary trajectories and may be adaptive. We recently identified an inverse plastic association between mutation rate and population density at 1 locus in 1 species of bacterium. It is unknown how widespread this association is, whether it varies among organisms, and what molecular mechanisms of mutagenesis or repair are required for this mutation-rate plasticity. Here, we address all 3 questions. We identify a strong negative association between mutation rate and population density across 70 years of published literature, comprising hundreds of mutation rates estimated using phenotypic markers of mutation (fluctuation tests) from all domains of life and viruses. We test this relationship experimentally, determining that there is indeed density-associated mutation-rate plasticity (DAMP) at multiple loci in both eukaryotes and bacteria, with up to 23-fold lower mutation rates at higher population densities. We find that the degree of plasticity varies, even among closely related organisms. Nonetheless, in each domain tested, DAMP requires proteins scavenging the mutagenic oxidised nucleotide 8-oxo-dGTP. This implies that phenotypic markers give a more precise view of mutation rate than previously believed: having accounted for other known factors affecting mutation rate, controlling for population density can reduce variation in mutation-rate estimates by 93%. Widespread DAMP, which we manipulate genetically in disparate organisms, also provides a novel trait to use in the fight against the evolution of antimicrobial resistance. Such a prevalent environmental association and conserved mechanism suggest that mutation has varied plastically with population density since the early origins of life.

Spontaneous mutation rate is a plastic trait associated with population density across domains of life

PubMed Central

Gifford, Danna R.; Hatcher, Charlie; Faulkner, Katy J.; Belavkin, Roman V.; Channon, Alastair; Aston, Elizabeth; McBain, Andrew J.

2017-01-01

Rates of random, spontaneous mutation can vary plastically, dependent upon the environment. Such plasticity affects evolutionary trajectories and may be adaptive. We recently identified an inverse plastic association between mutation rate and population density at 1 locus in 1 species of bacterium. It is unknown how widespread this association is, whether it varies among organisms, and what molecular mechanisms of mutagenesis or repair are required for this mutation-rate plasticity. Here, we address all 3 questions. We identify a strong negative association between mutation rate and population density across 70 years of published literature, comprising hundreds of mutation rates estimated using phenotypic markers of mutation (fluctuation tests) from all domains of life and viruses. We test this relationship experimentally, determining that there is indeed density-associated mutation-rate plasticity (DAMP) at multiple loci in both eukaryotes and bacteria, with up to 23-fold lower mutation rates at higher population densities. We find that the degree of plasticity varies, even among closely related organisms. Nonetheless, in each domain tested, DAMP requires proteins scavenging the mutagenic oxidised nucleotide 8-oxo-dGTP. This implies that phenotypic markers give a more precise view of mutation rate than previously believed: having accounted for other known factors affecting mutation rate, controlling for population density can reduce variation in mutation-rate estimates by 93%. Widespread DAMP, which we manipulate genetically in disparate organisms, also provides a novel trait to use in the fight against the evolution of antimicrobial resistance. Such a prevalent environmental association and conserved mechanism suggest that mutation has varied plastically with population density since the early origins of life. PMID:28837573

Fetal Alcohol Spectrum Disorders and Abnormal Neuronal Plasticity

PubMed Central

Medina, Alexandre E.

2012-01-01

The ingestion of alcohol during pregnancy can result in a group of neurobehavioral abnormalities collectively known as fetal alcohol spectrum disorders (FASD). During the past decade, studies using animal models indicated that early alcohol exposure can dramatically affect neuronal plasticity, an essential property of the central nervous system responsible for the normal wiring of the brain and involved in processes such as learning and memory. The abnormalities in neuronal plasticity caused by alcohol can explain many of the neurobehavioral deficits observed in FASD. Conversely, improving neuronal plasticity may have important therapeutic benefits. In this review, the author discuss the mechanisms that lead to these abnormalities and comment on recent pharmacological approaches that have been showing promising results in improving neuronal plasticity in FASD. PMID:21383101

Investigation of the plastic fracture of high-strength aluminum alloys

NASA Technical Reports Server (NTRS)

Van Stone, R. H.; Merchant, R. H.; Low, J. R., Jr.

1974-01-01

In a study of plastic fracture in five high-strength aluminum alloys (2014, 2024, 2124, 7075, and 7079), it has been shown that fracture toughness is affected primarily by the size and volume fraction of the larger (2 to 10 microms) second-phase particles. Certain of these particles crack at small plastic strains, nucleating voids which, with further plastic strain, coalesce to cause fracture. Not all second-phase particles crack at small plastic strains, and qualitative analysis of those which are primarily responsible for void nucleation shows that they contain iron or silicon or both. This result suggests that a reduction in the iron and silicon impurity content of the alloys should improve fracture toughness without loss of strength.

Rheology of the lithosphere and the folding caused by horizontal compression

NASA Astrophysics Data System (ADS)

Birger, B. I.

2015-05-01

The laboratory tests of rock specimens show that transient creep, at which deformations increase with time whereas strain rate decreases occurs when creep strains are sufficiently small. Since plate tectonics only permits small deformations in the lithospheric plates, the creep of the lithosphere is transient (non-steady-state). In this work, we study how the rheology of the lithosphere that possesses elasticity, brittleness (pseudo-plasticity), and creep affects the folding in the Earth's crust. Folding is caused by horizontal compression that results from the collision between the lithospheric plates. The effective viscosity characterizing the transient creep is lower than in the case of a steady-state creep and depends on the characteristic time of the considered process. The allowance for transient creep gives the distribution of the rheological properties of the horizontally compressed lithosphere in which the upper crust is brittle, whereas the lower crust and mantle lithosphere are dominated by transient creep. It is shown that the flows that arise in the lithosphere due to the instability under horizontal compression and cause folding are small-scale. These flows are concentrated in the upper brittle crust, they determine the short-wave Earth's surface topography, penetrate into the lower, creep-dominated crust to a shallow depth, and do not penetrate into the mantle. Therefore, these flows do not deform the Moho.

Modeling of the competition of stimulated Raman and Brillouin scatter in multiple beam experiments

NASA Astrophysics Data System (ADS)

Cohen, Bruce I.; Baldis, Hector A.; Berger, Richard L.; Estabrook, Kent G.; Williams, Edward A.; Labaune, Christine

2001-02-01

Multiple laser beam experiments with plastic target foils at the Laboratoire pour L'Utilisation des Lasers Intenses (LULI) facility [Baldis et al., Phys. Rev. Lett. 77, 2957 (1996)] demonstrated anticorrelation of stimulated Brillouin and Raman backscatter (SBS and SRS). Detailed Thomson scattering diagnostics showed that SBS always precedes SRS, that secondary electron plasma waves sometimes accompanied SRS appropriate to the Langmuir Decay Instability (LDI), and that, with multiple interaction laser beams, the SBS direct backscatter signal in the primary laser beam was reduced while the SRS backscatter signal was enhanced and occurred earlier in time. Analysis and numerical calculations are presented here that evaluate the influences on the competition of SBS and SRS, of local pump depletion in laser hot spots due to SBS, of mode coupling of SBS and LDI ion waves, and of optical mixing of secondary and primary laser beams. These influences can be significant. The calculations take into account simple models of the laser beam hot-spot intensity probability distributions and assess whether ponderomotive and thermal self-focusing are significant. Within the limits of the model, which omits several other potentially important nonlinearities, the calculations suggest the effectiveness of local pump depletion, ion wave mode coupling, and optical mixing in affecting the LULI observations.

Plastic deformation and instability in thin-walled tubes under combined loading : a general theory. Part II

NASA Astrophysics Data System (ADS)

Hill, Rodney

1999-02-01

This analysis concerns closed-ended tubes of circular section which are loaded by internal fluid pressure together with an external axial force. These may be applied in proportions that can be varied at will by servo-control during a single experiment. More generally it is envisaged that the servo-control can respond to changes in tube radius when these are monitored by a diametral extensometer. A main objective is to determine how the choice of control affects the regime of homogeneous deformation. Another is to consolidate an understanding of the transition to inhomogeneous deformation mediated by eigenmodes. The general approach is along similar lines to part I and takes the analysis appreciably farther in important respects. The constitutive basis is broadly classical, but yield functions spanning the whole of stress space are not called upon, primarily because of the extreme scarcity of good experimental data. There are counter-balancing benefits from this abstention : (i) the governing equations can be handled far more readily ; (ii) the structure of the mathematics as a whole is more transparent ; (iii) the final conclusions are valid for materials whose path-dependent behaviour is much more complex than can be accommodated by the simple theories reviewed in Part I.

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies.

PubMed

Bakker, Bjorn; Taudt, Aaron; Belderbos, Mirjam E; Porubsky, David; Spierings, Diana C J; de Jong, Tristan V; Halsema, Nancy; Kazemier, Hinke G; Hoekstra-Wakker, Karina; Bradley, Allan; de Bont, Eveline S J M; van den Berg, Anke; Guryev, Victor; Lansdorp, Peter M; Colomé-Tatché, Maria; Foijer, Floris

2016-05-31

Chromosome instability leads to aneuploidy, a state in which cells have abnormal numbers of chromosomes, and is found in two out of three cancers. In a chromosomal instable p53 deficient mouse model with accelerated lymphomagenesis, we previously observed whole chromosome copy number changes affecting all lymphoma cells. This suggests that chromosome instability is somehow suppressed in the aneuploid lymphomas or that selection for frequently lost/gained chromosomes out-competes the CIN-imposed mis-segregation. To distinguish between these explanations and to examine karyotype dynamics in chromosome instable lymphoma, we use a newly developed single-cell whole genome sequencing (scWGS) platform that provides a complete and unbiased overview of copy number variations (CNV) in individual cells. To analyse these scWGS data, we develop AneuFinder, which allows annotation of copy number changes in a fully automated fashion and quantification of CNV heterogeneity between cells. Single-cell sequencing and AneuFinder analysis reveals high levels of copy number heterogeneity in chromosome instability-driven murine T-cell lymphoma samples, indicating ongoing chromosome instability. Application of this technology to human B cell leukaemias reveals different levels of karyotype heterogeneity in these cancers. Our data show that even though aneuploid tumours select for particular and recurring chromosome combinations, single-cell analysis using AneuFinder reveals copy number heterogeneity. This suggests ongoing chromosome instability that other platforms fail to detect. As chromosome instability might drive tumour evolution, karyotype analysis using single-cell sequencing technology could become an essential tool for cancer treatment stratification.

Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus.

PubMed

Cleary, John D; Tomé, Stéphanie; López Castel, Arturo; Panigrahi, Gagan B; Foiry, Laurent; Hagerman, Katharine A; Sroka, Hana; Chitayat, David; Gourdon, Geneviève; Pearson, Christopher E

2010-09-01

Myotonic dystrophy, caused by DM1 CTG/CAG repeat expansions, shows varying instability levels between tissues and across ages within patients. We determined DNA replication profiles at the DM1 locus in patient fibroblasts and tissues from DM1 transgenic mice of various ages showing different instability. In patient cells, the repeat is flanked by two replication origins demarcated by CTCF sites, with replication diminished at the expansion. In mice, the expansion replicated from only the downstream origin (CAG as lagging template). In testes from mice of three different ages, replication toward the repeat paused at the earliest age and was relieved at later ages-coinciding with increased instability. Brain, pancreas and thymus replication varied with CpG methylation at DM1 CTCF sites. CTCF sites between progressing forks and repeats reduced replication depending on chromatin. Thus, varying replication progression may affect tissue- and age-specific repeat instability.

Pathways towards instability in financial networks

NASA Astrophysics Data System (ADS)

Bardoscia, Marco; Battiston, Stefano; Caccioli, Fabio; Caldarelli, Guido

2017-02-01

Following the financial crisis of 2007-2008, a deep analogy between the origins of instability in financial systems and complex ecosystems has been pointed out: in both cases, topological features of network structures influence how easily distress can spread within the system. However, in financial network models, the details of how financial institutions interact typically play a decisive role, and a general understanding of precisely how network topology creates instability remains lacking. Here we show how processes that are widely believed to stabilize the financial system, that is, market integration and diversification, can actually drive it towards instability, as they contribute to create cyclical structures which tend to amplify financial distress, thereby undermining systemic stability and making large crises more likely. This result holds irrespective of the details of how institutions interact, showing that policy-relevant analysis of the factors affecting financial stability can be carried out while abstracting away from such details.

Pathways towards instability in financial networks

PubMed Central

Bardoscia, Marco; Battiston, Stefano; Caccioli, Fabio; Caldarelli, Guido

2017-01-01

Following the financial crisis of 2007–2008, a deep analogy between the origins of instability in financial systems and complex ecosystems has been pointed out: in both cases, topological features of network structures influence how easily distress can spread within the system. However, in financial network models, the details of how financial institutions interact typically play a decisive role, and a general understanding of precisely how network topology creates instability remains lacking. Here we show how processes that are widely believed to stabilize the financial system, that is, market integration and diversification, can actually drive it towards instability, as they contribute to create cyclical structures which tend to amplify financial distress, thereby undermining systemic stability and making large crises more likely. This result holds irrespective of the details of how institutions interact, showing that policy-relevant analysis of the factors affecting financial stability can be carried out while abstracting away from such details. PMID:28221338

Electromechanical instability in soft materials: Theory, experiments and applications

NASA Astrophysics Data System (ADS)

Suo, Zhigang

2013-03-01

Subject to a voltage, a membrane of a dielectric elastomer reduces thickness and expands area, possibly straining over 100%. The phenomenon is being developed as transducers for broad applications, including soft robots, adaptive optics, Braille displays, and electric generators. The behavior of dielectric elastomers is closely tied to electromechanical instability. This instability may limit the performance of devices, and may also be used to achieve giant actuation strains. This talk reviews the theory of dielectric elastomers, coupling large deformation and electric potential. The theory is developed within the framework of continuum mechanics and thermodynamics. The theory attempts to answer commonly asked questions. How do mechanics and electrostatics work together to generate large deformation? How efficiently can a material convert energy from one form to another? How do molecular processes affect macroscopic behavior? The theory is used to describe electromechanical instability, and is related to recent experiments.

Rb1 haploinsufficiency promotes telomere attrition and radiation-induced genomic instability.

PubMed

Gonzalez-Vasconcellos, Iria; Anastasov, Natasa; Sanli-Bonazzi, Bahar; Klymenko, Olena; Atkinson, Michael J; Rosemann, Michael

2013-07-15

Germline mutations of the retinoblastoma gene (RB1) predispose to both sporadic and radiation-induced osteosarcoma, tumors characterized by high levels of genomic instability, and activation of alternative lengthening of telomeres. Mice with haploinsufficiency of the Rb1 gene in the osteoblastic lineage reiterate the radiation susceptibility to osteosarcoma seen in patients with germline RB1 mutations. We show that the susceptibility is accompanied by an increase in genomic instability, resulting from Rb1-dependent telomere erosion. Radiation exposure did not accelerate the rate of telomere loss but amplified the genomic instability resulting from the dysfunctional telomeres. These findings suggest that telomere maintenance is a noncanonical caretaker function of the retinoblastoma protein, such that its deficiency in cancer may potentiate DNA damage-induced carcinogenesis by promoting formation of chromosomal aberrations, rather than simply by affecting cell-cycle control. ©2013 AACR.

Pathways towards instability in financial networks.

PubMed

Bardoscia, Marco; Battiston, Stefano; Caccioli, Fabio; Caldarelli, Guido

2017-02-21

Following the financial crisis of 2007-2008, a deep analogy between the origins of instability in financial systems and complex ecosystems has been pointed out: in both cases, topological features of network structures influence how easily distress can spread within the system. However, in financial network models, the details of how financial institutions interact typically play a decisive role, and a general understanding of precisely how network topology creates instability remains lacking. Here we show how processes that are widely believed to stabilize the financial system, that is, market integration and diversification, can actually drive it towards instability, as they contribute to create cyclical structures which tend to amplify financial distress, thereby undermining systemic stability and making large crises more likely. This result holds irrespective of the details of how institutions interact, showing that policy-relevant analysis of the factors affecting financial stability can be carried out while abstracting away from such details.

Instability, finite amplitude pulsation and mass-loss in models of massive OB-type stars

NASA Astrophysics Data System (ADS)

Yadav, Abhay Pratap; Glatzel, Wolfgang

2017-11-01

Variability and mass-loss are common phenomena in massive OB-type stars. It is argued that they are caused by violent strange mode instabilities identified in corresponding stellar models. We present a systematic linear stability analysis with respect to radial perturbations of massive OB-type stars with solar chemical composition and masses between 23 and 100 M⊙. For selected unstable stellar models, we perform non-linear simulations of the evolution of the instabilities into the non-linear regime. Finite amplitude pulsations with periods in the range between hours and 100 d are found to be the final result of the instabilities. The pulsations are associated with a mean acoustic luminosity which can be the origin of a pulsationally driven wind. Corresponding mass-loss rates lie in the range between 10-9 and 10-4 M⊙ yr-1 and may thus affect the evolution of massive stars.

Interaction between emotional state and learning underlies mood instability.

PubMed

Eldar, Eran; Niv, Yael

2015-01-21

Intuitively, good and bad outcomes affect our emotional state, but whether the emotional state feeds back onto the perception of outcomes remains unknown. Here, we use behaviour and functional neuroimaging of human participants to investigate this bidirectional interaction, by comparing the evaluation of slot machines played before and after an emotion-impacting wheel-of-fortune draw. Results indicate that self-reported mood instability is associated with a positive-feedback effect of emotional state on the perception of outcomes. We then use theoretical simulations to demonstrate that such positive feedback would result in mood destabilization. Taken together, our results suggest that the interaction between emotional state and learning may play a significant role in the emergence of mood instability.

Plasticizer endocrine disruption: Highlighting developmental and reproductive effects in mammals and non-mammalian aquatic species.

PubMed

Mathieu-Denoncourt, Justine; Wallace, Sarah J; de Solla, Shane R; Langlois, Valerie S

2015-08-01

Due to their versatility, robustness, and low production costs, plastics are used in a wide variety of applications. Plasticizers are mixed with polymers to increase flexibility of plastics. However, plasticizers are not covalently bound to plastics, and thus leach from products into the environment. Several studies have reported that two common plasticizers, bisphenol A (BPA) and phthalates, induce adverse health effects in vertebrates; however few studies have addressed their toxicity to non-mammalian species. The aim of this review is to compare the effects of plasticizers in animals, with a focus on aquatic species. In summary, we identified three main chains of events that occur in animals exposed to BPA and phthalates. Firstly, plasticizers affect development by altering both the thyroid hormone and growth hormone axes. Secondly, these chemicals interfere with reproduction by decreasing cholesterol transport through the mitochondrial membrane, leading to reduced steroidogenesis. Lastly, exposure to plasticizers leads to the activation of peroxisome proliferator-activated receptors, the increase of fatty acid oxidation, and the reduction in the ability to cope with the augmented oxidative stress leading to reproductive organ malformations, reproductive defects, and decreased fertility. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

7 CFR 42.114 - Procedures for evaluating interior container defects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... affecting usability 201 Black spots in metal container 202 Enamel missing (when required) in metal container..., plastic, paper, rigid, etc.) e.g., interior damage, tear, delamination, missing layer, off-odor, interior..., plastic, paper, rigid, etc.) e.g., interior damage, tear, delamination, missing layer, off-odor, interior...

40 CFR 60.390 - Applicability and designation of affected facility.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Performance for Automobile and Light Duty Truck Surface Coating Operations § 60.390 Applicability and... facilities in an automobile or light-duty truck assembly plant: each prime coat operation, each guide coat... to coat plastic body components or all-plastic automobile or light-duty truck bodies on separate...

40 CFR 60.390 - Applicability and designation of affected facility.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Performance for Automobile and Light Duty Truck Surface Coating Operations § 60.390 Applicability and... facilities in an automobile or light-duty truck assembly plant: each prime coat operation, each guide coat... to coat plastic body components or all-plastic automobile or light-duty truck bodies on separate...

40 CFR 60.390 - Applicability and designation of affected facility.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Performance for Automobile and Light Duty Truck Surface Coating Operations § 60.390 Applicability and... facilities in an automobile or light-duty truck assembly plant: each prime coat operation, each guide coat... to coat plastic body components or all-plastic automobile or light-duty truck bodies on separate...

Forming limit curves of DP600 determined in high-speed Nakajima tests and predicted by two different strain-rate-sensitive models

NASA Astrophysics Data System (ADS)

Weiß-Borkowski, Nathalie; Lian, Junhe; Camberg, Alan; Tröster, Thomas; Münstermann, Sebastian; Bleck, Wolfgang; Gese, Helmut; Richter, Helmut

2018-05-01

Determination of forming limit curves (FLC) to describe the multi-axial forming behaviour is possible via either experimental measurements or theoretical calculations. In case of theoretical determination, different models are available and some of them consider the influence of strain rate in the quasi-static and dynamic strain rate regime. Consideration of the strain rate effect is necessary as many material characteristics such as yield strength and failure strain are affected by loading speed. In addition, the start of instability and necking depends not only on the strain hardening coefficient but also on the strain rate sensitivity parameter. Therefore, the strain rate dependency of materials for both plasticity and the failure behaviour is taken into account in crash simulations for strain rates up to 1000 s-1 and FLC can be used for the description of the material's instability behaviour at multi-axial loading. In this context, due to the strain rate dependency of the material behaviour, an extrapolation of the quasi-static FLC to dynamic loading condition is not reliable. Therefore, experimental high-speed Nakajima tests or theoretical models shall be used to determine the FLC at high strain rates. In this study, two theoretical models for determination of FLC at high strain rates and results of experimental high-speed Nakajima tests for a DP600 are presented. One of the theoretical models is the numerical algorithm CRACH as part of the modular material and failure model MF GenYld+CrachFEM 4.2, which is based on an initial imperfection. Furthermore, the extended modified maximum force criterion considering the strain rate effect is also used to predict the FLC. These two models are calibrated by the quasi-static and dynamic uniaxial tensile tests and bulge tests. The predictions for the quasi-static and dynamic FLC by both models are presented and compared with the experimental results.

Resistance of a directionally solidified gamma/gamma prime-delta eutectic alloy to recrystallization. [Ni-base alloy

NASA Technical Reports Server (NTRS)

Tewari, S. N.; Scheuermann, C. M.; Andrews, C. W.

1976-01-01

A lamellar nickel-base directionally-solidified eutectic gamma/gamma prime-delta alloy has potential as an advanced gas turbine blade material. The microstructural stability of this alloy was investigated. Specimens were plastically deformed by uniform compression or Brinell indentation, then annealed between 750 and 1120 C. Microstructural changes observed after annealing included gamma prime coarsening, pinch-off and spheroidization of delta lamellae, and appearance of an unidentified blocky phase in surface layers. All but the first of these was localized in severely deformed regions, suggesting that microstructural instability may not be a serious problem in the use of this alloy.

Resistance of a gamma/gamma prime - delta directionally solidified eutectic alloy to recrystallization

NASA Technical Reports Server (NTRS)

Tewari, S. N.; Scheuermann, C. M.; Andrews, C. W.

1975-01-01

The lamellar directionally solidified nickel-base eutectic alloy gamma/gamma prime-delta has potential as an advanced turbine blade material. The microstructural stability of this alloy was investigated. Specimens were plastically deformed by uniform compression or Brinell indentation, then annealed between 705 and 1120 C. Microstructural changes observed after annealing included gamma prime coarsening, pinch-off and spheroidization of delta lamellae, and the appearance of an unidentified blocky phase in surface layers. All but the first of these was localized in severely deformed regions, suggesting that microstructural instability is not a serious problem in the use of this alloy.

Investigation of the effect of electric current on serrated deformation and acoustic emission in the aluminum-magnesium alloy 5056

NASA Astrophysics Data System (ADS)

Shibkov, A. A.; Denisov, A. A.; Zheltov, M. A.; Zolotov, A. E.; Gasanov, M. F.; Ivolgin, V. I.

2015-06-01

The effect of direct electric current on the serrated deformation of the aluminum-magnesium alloy 5056 has been studied using the acoustic emission method and high-speed video filming of propagating deformation bands. The phenomenon of the electric current-induced suppression of low-frequency acoustic emission signals has been revealed in the range of 1 Hz-2 kHz, which is connected with the development of Portevin-Le Chatelier deformation bands. The characteristic times of damping and growth of plastic instabilities and acoustic signals caused by them after current turn-on and turn-off, respectively, have been estimated.

The role of hot electrons in the dynamics of a laser-driven strong converging shock

DOE PAGES

Llor Aisa, E.; Ribeyre, X.; Duchateau, G.; ...

2017-11-30

Experiments on strong shock excitation in spherical plastic targets conducted at the Omega Laser Facility are interpreted with the radiation–hydrodynamics code CHIC to account for parametric instabilities excitation and hot-electron generation. The effects of hot electrons on the shock-pressure amplification and upstream preheat are analyzed. In this study, it is demonstrated that both effects contribute to an increase in shock velocity. Comparison of the measured laser reflectivity and shock flash time with numerical simulations make it possible to reconstitute the time history of the ablation and shock pressures. Finally, consequences of this analysis for the shock-ignition target design are discussed.

Investigation of Multiscale and Multiphase Flow, Transport and Reaction in Heavy Oil Recovery Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yortsos, Yanis C.

In this report, the thrust areas include the following: Internal drives, vapor-liquid flows, combustion and reaction processes, fluid displacements and the effect of instabilities and heterogeneities and the flow of fluids with yield stress. These find respective applications in foamy oils, the evolution of dissolved gas, internal steam drives, the mechanics of concurrent and countercurrent vapor-liquid flows, associated with thermal methods and steam injection, such as SAGD, the in-situ combustion, the upscaling of displacements in heterogeneous media and the flow of foams, Bingham plastics and heavy oils in porous media and the development of wormholes during cold production.

The role of hot electrons in the dynamics of a laser-driven strong converging shock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Llor Aisa, E.; Ribeyre, X.; Duchateau, G.

Experiments on strong shock excitation in spherical plastic targets conducted at the Omega Laser Facility are interpreted with the radiation–hydrodynamics code CHIC to account for parametric instabilities excitation and hot-electron generation. The effects of hot electrons on the shock-pressure amplification and upstream preheat are analyzed. In this study, it is demonstrated that both effects contribute to an increase in shock velocity. Comparison of the measured laser reflectivity and shock flash time with numerical simulations make it possible to reconstitute the time history of the ablation and shock pressures. Finally, consequences of this analysis for the shock-ignition target design are discussed.

The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex

PubMed Central

Pattwell, Siobhan S.; Bath, Kevin G.; Perez-Castro, Rosalia; Lee, Francis S.; Chao, Moses V.; Ninan, Ipe

2012-01-01

The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is a common human single nucleotide polymorphism (SNP) that affects the regulated release of BDNF, and has been implicated in affective disorders and cognitive dysfunction. A decreased activation of the infralimbic medial prefrontal cortex (IL-mPFC), a brain region critical for the regulation of affective behaviors, has been described in BDNFMet carriers. However, it is unclear whether and how the Val66Met polymorphism affects the IL-mPFC synapses. Here we report that spike timing-dependent plasticity (STDP) was absent in the IL-mPFC pyramidal neurons from BDNFMet/Met mice, a mouse that recapitulates the specific phenotypic properties of the human BDNF Val66Met polymorphism. Also, we observed a decrease in N-methyl-D-aspartic acid (NMDA) and γ-aminobutyric acid (GABA) receptor-mediated synaptic transmission in the pyramidal neurons of BDNFMet/Met mice. While BDNF enhanced non-NMDA receptor transmission and depressed GABA receptor transmission in the wild-type mice, both effects were absent in BDNFMet/Met mice after BDNF treatment. Indeed, exogenous BDNF reversed the deficits in STDP and NMDA receptor transmission in BDNFMet/Met neurons. BDNF-mediated selective reversal of the deficit in plasticity and NMDA receptor transmission, but its lack of effect on GABA and non-NMDA receptor transmission in BDNFMet/Met mice, suggests separate mechanisms of Val66Met polymorphism upon synaptic transmission. The effect of the Val66Met polymorphism on synaptic transmission and plasticity in the IL-mPFC represents a mechanism to account for this SNP's impact on affective disorders and cognitive dysfunction. PMID:22396415

Loss of heterozygosity and microsatellite instability are rare in sporadic dedifferentiated liposarcoma: a study of 43 well-characterized cases.

PubMed

Davis, Jessica L; Grenert, James P; Horvai, Andrew E

2014-06-01

Defects in mismatch repair proteins have been identified in Lynch syndrome-associated liposarcomas, as well as in rare sporadic sarcomas. However, it is unclear if mismatch repair defects have a role in sarcoma tumorigenesis. Microsatellite instability is a surrogate marker of mismatch repair defects. To determine whether sporadic dedifferentiated liposarcomas display microsatellite instability and, if so, to evaluate whether such instability differs between the lipogenic and nonlipogenic components of these tumors. The diagnoses of conventional dedifferentiated liposarcoma were confirmed by a combination of morphologic, immunophenotypic, and molecular studies. Standard fluorescence-based polymerase chain reaction, including 5 mononucleotide microsatellite markers (BAT25, BAT26, NR21, NR24, and MONO27), as well as 2 pentanucleotide repeat markers (Penta C and Penta D), was used to test for instability and loss of heterozygosity. We demonstrated only a single case (1 of 43) with microsatellite instability at one mononucleotide marker. No sarcomas showed high-level microsatellite instability. However, loss of heterozygosity at the pentanucleotide markers was observed in 8 of 43 cases. The presence of loss of heterozygosity was overrepresented in the nonlipogenic (dedifferentiated) components compared with the paired lipogenic (well differentiated) components. Mismatch repair defects do not contribute to sporadic dedifferentiated liposarcoma tumorigenesis. Whether the observed loss of heterozygosity drives tumorigenesis in liposarcoma, for example by affecting tumor suppressor or cell cycle regulator genes, remains to be determined.

Temperature and food mediate long-term thermotactic behavioral plasticity by association-independent mechanisms in C. elegans.

PubMed

Chi, Cynthia A; Clark, Damon A; Lee, Stella; Biron, David; Luo, Linjiao; Gabel, Christopher V; Brown, Jeffrey; Sengupta, Piali; Samuel, Aravinthan D T

2007-11-01

Thermotactic behavior in the nematode Caenorhabditis elegans exhibits long-term plasticity. On a spatial thermal gradient, C. elegans tracks isotherms near a remembered set-point (T(S)) corresponding to its previous cultivation temperature. When navigating at temperatures above its set-point (T>T(S)), C. elegans crawls down spatial thermal gradients towards the T(S) in what is called cryophilic movement. The T(S) retains plasticity in the adult stage and is reset by approximately 4 h of sustained exposure to a new temperature. Long-term plasticity in C. elegans thermotactic behavior has been proposed to represent an associative learning of specific temperatures conditioned in the presence or absence of bacterial food. Here, we use quantitative behavioral assays to define the temperature and food-dependent determinants of long-term plasticity in the different modes of thermotactic behavior. Under our experimental conditions, we find that starvation at a specific temperature neither disrupts T(S) resetting toward the starvation temperature nor induces learned avoidance of the starvation temperature. We find that prolonged starvation suppresses the cryophilic mode of thermotactic behavior. The hen-1 and tax-6 genes have been reported to affect associative learning between temperature and food-dependent cues. Under our experimental conditions, mutation in the hen-1 gene, which encodes a secreted protein with an LDL receptor motif, does not significantly affect thermotactic behavior or long-term plasticity. Mutation in the tax-6 calcineurin gene abolishes thermotactic behavior altogether. In summary, we do not find evidence that long-term plasticity requires association between temperature and the presence or absence of bacterial food.

Curvature-Induced Instabilities of Shells

NASA Astrophysics Data System (ADS)

Pezzulla, Matteo; Stoop, Norbert; Steranka, Mark P.; Bade, Abdikhalaq J.; Holmes, Douglas P.

2018-01-01

Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of spontaneous curvature and geometric frustration in curved shells remains poorly understood. Via a combination of precision experiments on elastomeric spherical shells, simulations, and theory, we show how a spontaneous curvature induces a rotational symmetry-breaking buckling as well as a snapping instability reminiscent of the Venus fly trap closure mechanism. The instabilities, and their dependence on geometry, are rationalized by reducing the spontaneous curvature to an effective mechanical load. This formulation reveals a combined pressurelike term in the bulk and a torquelike term in the boundary, allowing scaling predictions for the instabilities that are in excellent agreement with experiments and simulations. Moreover, the effective pressure analogy suggests a curvature-induced subcritical buckling in closed shells. We determine the critical buckling curvature via a linear stability analysis that accounts for the combination of residual membrane and bending stresses. The prominent role of geometry in our findings suggests the applicability of the results over a wide range of scales.

Shear-Flow Instability Saturation by Stable Modes: Hydrodynamics and Gyrokinetics

NASA Astrophysics Data System (ADS)

Fraser, Adrian; Pueschel, M. J.; Terry, P. W.; Zweibel, E. G.

2017-10-01

We present simulations of shear-driven instabilities, focusing on the impact of nonlinearly excited, large-scale, linearly stable modes on the nonlinear cascade, momentum transport, and secondary instabilities. Stable modes, which have previously been shown to significantly affect instability saturation [Fraser et al. PoP 2017], are investigated in a collisionless, gyrokinetic, periodic zonal flow using the Gene code by projecting the results of nonlinear simulations onto a basis of linear eigenmodes that includes both stable and unstable modes. Benchmarking growth rates against previous gyrokinetic studies and an equivalent fluid system demonstrates comparable linear dynamics in the fluid and gyrokinetic systems. Cases of driven and decaying shear-flow turbulence are compared in Gene by using a Krook operator as an effective forcing. For comparison with existing hydrodynamic and MHD shear-flow instability studies, we present results for the shear layer obtained by similar means with the code Dedalus. Supported by U.S. DOE Grant No. DE-FG02-89ER53291, the NSF, and UW-Madison.

Spatial features of synaptic adaptation affecting learning performance.

PubMed

Berger, Damian L; de Arcangelis, Lucilla; Herrmann, Hans J

2017-09-08

Recent studies have proposed that the diffusion of messenger molecules, such as monoamines, can mediate the plastic adaptation of synapses in supervised learning of neural networks. Based on these findings we developed a model for neural learning, where the signal for plastic adaptation is assumed to propagate through the extracellular space. We investigate the conditions allowing learning of Boolean rules in a neural network. Even fully excitatory networks show very good learning performances. Moreover, the investigation of the plastic adaptation features optimizing the performance suggests that learning is very sensitive to the extent of the plastic adaptation and the spatial range of synaptic connections.

Hub vortex instability within wind turbine wakes: Effects of wind turbulence, loading conditions, and blade aerodynamics

NASA Astrophysics Data System (ADS)

Ashton, Ryan; Viola, Francesco; Camarri, Simone; Gallaire, Francois; Iungo, Giacomo Valerio

2016-11-01

The near wake of wind turbines is characterized by the presence of the hub vortex, which is a coherent vorticity structure generated from the interaction between the root vortices and the boundary layer evolving over the turbine nacelle. By moving downstream, the hub vortex undergoes an instability with growth rate, azimuthal and axial wavenumbers determined by the characteristics of the incoming wind and turbine aerodynamics. Thus, a large variability of the hub vortex instability is expected for wind energy applications with consequent effects on wake downstream evolution, wake interactions within a wind farm, power production, and fatigue loads on turbines invested by wakes generated upstream. In order to predict characteristics of the hub vortex instability for different operating conditions, linear stability analysis is carried out by considering different statistics of the incoming wind turbulence, thrust coefficient, tip speed ratio, and blade lift distribution of a wind turbine. Axial and azimuthal wake velocity fields are modeled through Carton-McWilliams velocity profiles by mimicking the presence of the hub vortex, helicoidal tip vortices, and matching the wind turbine thrust coefficient predicted through the actuator disk model. The linear stability analysis shows that hub vortex instability is strongly affected by the wind turbine loading conditions, and specifically it is promoted by a larger thrust coefficient. A higher load of the wind turbines produces an enhanced axial velocity deficit and, in turn, higher shear in the radial direction of the streamwise velocity. The axial velocity shear within the turbine wake is also the main physical mechanism promoting the hub vortex instability when varying the lift distribution over the blade span for a specific loading condition. Cases with a larger velocity deficit in proximity of the wake center and less aerodynamic load towards the blade tip result to be more unstable. Moreover, wake swirl promotes hub vortex instability, and it can also affect the azimuthal wave number of the most unstable mode. Finally, higher Reynolds stresses and turbulent eddy viscosity decrease both growth rate and azimuthal wave number of the most unstable mode.

Disease-associated repeat instability and mismatch repair.

PubMed

Schmidt, Monika H M; Pearson, Christopher E

2016-02-01

Expanded tandem repeat sequences in DNA are associated with at least 40 human genetic neurological, neurodegenerative, and neuromuscular diseases. Repeat expansion can occur during parent-to-offspring transmission, and arise at variable rates in specific tissues throughout the life of an affected individual. Since the ongoing somatic repeat expansions can affect disease age-of-onset, severity, and progression, targeting somatic expansion holds potential as a therapeutic target. Thus, understanding the factors that regulate this mutation is crucial. DNA repair, in particular mismatch repair (MMR), is the major driving force of disease-associated repeat expansions. In contrast to its anti-mutagenic roles, mammalian MMR curiously drives the expansion mutations of disease-associated (CAG)·(CTG) repeats. Recent advances have broadened our knowledge of both the MMR proteins involved in disease repeat expansions, including: MSH2, MSH3, MSH6, MLH1, PMS2, and MLH3, as well as the types of repeats affected by MMR, now including: (CAG)·(CTG), (CGG)·(CCG), and (GAA)·(TTC) repeats. Mutagenic slipped-DNA structures have been detected in patient tissues, and the size of the slip-out and their junction conformation can determine the involvement of MMR. Furthermore, the formation of other unusual DNA and R-loop structures is proposed to play a key role in MMR-mediated instability. A complex correlation is emerging between tissues showing varying amounts of repeat instability and MMR expression levels. Notably, naturally occurring polymorphic variants of DNA repair genes can have dramatic effects upon the levels of repeat instability, which may explain the variation in disease age-of-onset, progression and severity. An increasing grasp of these factors holds prognostic and therapeutic potential. Copyright © 2015 Elsevier B.V. All rights reserved.

Seasonal plasticity in telencephalon mass of a benthic fish.

PubMed

McCallum, E S; Capelle, P M; Balshine, S

2014-11-01

To gain a deeper understanding of how environmental conditions affect brain plasticity, brain size was explored across different seasons using the invasive round goby Neogobius melanostomus. The results show that N. melanostomus had heavier telencephalon in the spring compared to the autumn across the two years of study. Furthermore, fish in reproductive condition had heavier telencephala, indicating that tissue investment and brain plasticity may be related to reproductive needs in N. melanostomus. © 2014 The Fisheries Society of the British Isles.

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

PubMed Central

Mellios, Nikolaos; Sugihara, Hiroki; Castro, Jorge; Banerjee, Abhishek; Le, Chuong; Kumar, Arooshi; Crawford, Benjamin; Strathmann, Julia; Tropea, Daniela; Levine, Stuart S.; Edbauer, Dieter; Sur, Mriganka

2011-01-01

Using multiple quantitative analyses, we discovered microRNAs (miRNAs) abundantly expressed in visual cortex that respond to dark-rearing (DR) and/or monocular deprivation (MD). The most significantly altered miRNA, miR-132, was rapidly upregulated after eye-opening and delayed by DR. In vivo inhibition of miR-132 prevented ocular dominance plasticity in identified neurons following MD, and affected maturation of dendritic spines, demonstrating its critical role in the plasticity of visual cortex circuits. PMID:21892155

A Unified Theory of Penetration

DTIC Science & Technology

1986-12-01

occur for jets penetrating plastics as will be mentioned later. For very high impact speeds, (1.13) melting and vaporization may also become important... plastic flow in a target is P - 3Y (1.2) we can calculate the resistive force of the target due to its hardness as a - pA - 3YtA - 3C (BHN) A (1.3) t...projectile can affect its penetration, especially as it enters the target, or if the target is thin, and projectile plastic (1.22) deformation and/or erosion

Sleep Instabilities Assessed by Cardiopulmonary Coupling Analysis Increase During Childhood and Adolescence.

PubMed

Cysarz, Dirk; Linhard, Maijana; Seifert, Georg; Edelhäuser, Friedrich

2018-01-01

The electrocardiogram-based cardiopulmonary coupling (CPC) technique may be used to track sleep instabilities. With progressing age, maturational changes during childhood and adolescence affect sleep. The objective was to assess developmental changes in sleep instabilities in a natural setting. ECGs during nighttime sleep on regular school days were recorded from 363 subjects aged 4 to 22 years (204 females). The estimated total sleep time (ETST) decreased from 598 to 445 min during childhood and adolescence. Stable sleep linearly decreased with progressing age (high frequency coupling (HFC): 70-48% ETST). Unstable sleep [low frequency coupling (LFC): 9-19% ETST], sleep fragmentation or disordered breathing (elevated LFC: 4-12% ETST), and wake/REM states [very low frequency coupling (VLFC): 20-32% ETST] linearly increased with age. Hence, with progressing age the sleep of children and adolescents shortens, becomes more unstable and is more often affected by fragmentation or sleep disordered breathing, especially in the age group >13 years. It remains to be clarified whether some of the changes are caused by a social jetlag, i.e., the misalignment of body clock and social time especially in adolescents.

Polymer blends used for the aqueous coating of solid dosage forms: importance of the type of plasticizer.

PubMed

Lecomte, F; Siepmann, J; Walther, M; MacRae, R J; Bodmeier, R

2004-09-14

The aim of this study was to investigate the importance of the type of plasticizer in polymer blends used for the coating of solid dosage forms, comparing a lipophilic and a hydrophilic plasticizer (dibutyl sebacate (DBS) and triethyl citrate (TEC)). In vitro drug release from propranolol hydrochloride (propranolol HCl)-loaded pellets coated with blends of ethyl cellulose (EC) and Eudragit L (100:0, 75:25, 50:50, 25:75 and 0:100 w/w) was investigated at low as well as at high pH. To better understand the underlying mass transport mechanisms, the physicochemical properties of the film coatings (e.g. mechanical resistance, water uptake and dry weight loss behavior) were determined. Interestingly, drug release strongly depended on the type of plasticizer. Importantly, not only the slope but also the shape of the release curves was affected, indicating that the chemical nature of the plasticizer plays a major role for the underlying drug release mechanisms. Diffusion through the intact polymer coatings and/or through water-filled cracks was found to be dominating for the control of drug release. The relative importance of these pathways strongly depended on the polymer blend ratio and type of plasticizer. In contrast to DBS, TEC rapidly leached out of the coatings, resulting in decreasing mechanical resistances of the films and, thus, facilitated crack formation. In addition, the hydrophilicity of the plasticizer significantly affected the water uptake behavior of the film coatings and, hence, changes in the coatings' toughness and drug permeability. Also the relative affinity of the plasticizer to the different polymers was found to be of significance. In contrast to TEC, DBS has a higher affinity to EC than to Eudragit L, resulting in potential redistributions of this plasticizer within the polymeric systems and changes in the release profiles during storage. Importantly, these effects could be avoided with appropriate curing conditions and preparation techniques for the coating dispersions.

Core Characteristics Deterioration due to Plastic Deformation

NASA Astrophysics Data System (ADS)

Kaido, Chikara; Arai, Satoshi

This paper discusses the effect of plastic deformation at core manufacturing on the characteristics of cores where non-oriented electrical steel sheets are used as core material. Exciting field and iron loss increase proportionally to plastic deformation in the case of rP<10, where rP is a ratio of plastic deformation to that at yield point. In this region, anomalous eddy currents increase because plastic deformations of crystalline grains are distributed and then the flux distribution is induced. In the case of rP>20, the deterioration tend to saturate, and the increases in magnetic field and iron loss are 1000 to 1500A/m and 2 to 4W/kg. They are related to grain size, and high grade with larger grain may have lager field increase and smaller iron loss increase. Anomalous eddy current losses scarcely increase in this region. In actual motors, the plastic deformation affects iron loss increase although exciting current increases a little.

Micro-plastic ingestion by waterbirds from contaminated wetlands in South Africa.

PubMed

Reynolds, Chevonne; Ryan, Peter G

2018-01-01

Despite a large literature on the impacts of micro-plastic pollution in marine ecosystems, very little research has focused on these pollutants in freshwater ecosystems. Recently, however, a few studies have demonstrated that micro-plastic pollutants are ingested by freshwater taxa, including birds. To explore this potential environmental threat in African freshwater systems we quantified micro-plastic pollutants in the faeces and feather brushings of seven southern African duck species. We analysed 283 faecal samples and 408 feather brushings, and found that 5% of faecal samples and 10% of feather samples contained micro-plastic fibres. The presence and abundance of micro-fibres differed between sampling sites, with significantly higher amounts recorded for the site that received effluent from a sewage treatment facility. Additionally, micro-fibre presence differed across duck species, indicating that foraging behaviour affects plastic ingestion. Our study confirms that African freshwater ecosystems and the biodiversity they support are under threat from micro-plastic contamination. Copyright © 2017 Elsevier Ltd. All rights reserved.

The effects of hormones and physical exercise on hippocampal structural plasticity.

PubMed

Triviño-Paredes, Juan; Patten, Anna R; Gil-Mohapel, Joana; Christie, Brian R

2016-04-01

The hippocampus plays an integral role in certain aspects of cognition. Hippocampal structural plasticity and in particular adult hippocampal neurogenesis can be influenced by several intrinsic and extrinsic factors. Here we review how hormones (i.e., intrinsic modulators) and physical exercise (i.e., an extrinsic modulator) can differentially modulate hippocampal plasticity in general and adult hippocampal neurogenesis in particular. Specifically, we provide an overview of the effects of sex hormones, stress hormones, and metabolic hormones on hippocampal structural plasticity and adult hippocampal neurogenesis. In addition, we also discuss how physical exercise modulates these forms of hippocampal plasticity, giving particular emphasis on how this modulation can be affected by variables such as exercise regime, duration, and intensity. Understanding the neurobiological mechanisms underlying the modulation of hippocampal structural plasticity by intrinsic and extrinsic factors will impact the design of new therapeutic approaches aimed at restoring hippocampal plasticity following brain injury or neurodegeneration. Copyright © 2016 Elsevier Inc. All rights reserved.

The plastic-associated microorganisms of the North Pacific Gyre.

PubMed

Carson, Henry S; Nerheim, Magnus S; Carroll, Katherine A; Eriksen, Marcus

2013-10-15

Microorganisms likely mediate processes affecting the fate and impacts of marine plastic pollution, including degradation, chemical adsorption, and colonization or ingestion by macroorganisms. We investigated the relationship between plastic-associated microorganism communities and factors such as location, temperature, salinity, plankton abundance, plastic concentration, item size, surface roughness, and polymer type. Small plastic items from the surface of the North Pacific Gyre in 2011 were examined using scanning electron microscopy. Bacillus bacteria (mean 1664 ± 247 individuals mm(-2)) and pennate diatoms (1097 ± 154 mm(-2)) were most abundant, with coccoid bacteria, centric diatoms, dinoflagellates, coccolithophores, and radiolarians present. Bacterial abundance was patchy, but increased on foamed polystyrene. Diatom abundance increased on items with rough surfaces and at sites with high plastic concentrations. Morphotype richness increased slightly on larger fragments, and a biogeographic transition occurred between pennate diatom groups. Better characterizing this community will aid in understanding how it interacts with plastic pollution. Copyright © 2013 Elsevier Ltd. All rights reserved.

High prevalence of parental delivery of plastic debris in Cory's shearwaters (Calonectris diomedea).

PubMed

Rodríguez, Airam; Rodríguez, Beneharo; Nazaret Carrasco, María

2012-10-01

Plastic ingestion by adult Procellariiformes has been widely recorded, but few studies have evaluated intergenerational transfer. We assessed the prevalence of plastic particles, as well as their basic characteristics, in the gut content of dead Cory's shearwater fledglings stranded by light pollution on Canary Islands. Eighty-three percent of birds were affected, containing on average 8.0 plastic pieces per bird. The average plastic weight per bird was low (2.97±3.97mg) compared with other petrel species. We found no relationships between plastic loads and body condition or body size, but negative effects may be hidden or delayed. We propose to use the fledglings stranded by light pollution to carry out more precise studies to understand the potential hidden costs of plastic ingestion; and to monitor in a long-term the marine debris to develop management actions for the control of pollution at the marine environment. Copyright © 2012 Elsevier Ltd. All rights reserved.

Atlantooccipital overlapping and its effect on outcomes after ventral fixation in dogs with atlantoaxial instability

PubMed Central

TAKAHASHI, Fumitaka; HAKOZAKI, Takaharu; KOUNO, Shigenori; SUZUKI, Shuji; SATO, Asaka; KANNO, Nobuo; HARADA, Yasuji; YAMAGUCHI, Shinya; HARA, Yasushi

2018-01-01

We compared clinical outcomes after ventral fixation in dogs with atlantoaxial instability (AAI) on the basis of the presence or absence of atlantooccipital overlapping (AOO). Of 41 dogs diagnosed with AAI and treated ventral fixation, 12 exhibited AOO (AOO group), whereas 29 did not (non-AOO group). The AOO group had significantly higher neurological scores before (P=0.024) and 1 month after (P=0.033) surgery compared with the non-AOO group; however, no significant differences were observed between the groups 2 months after surgery. The presence of complicating AOO affected the clinical signs for dogs with AAI, but did not directly affect the outcome of surgical stabilization of AAI. PMID:29398673

Phenotypic plasticity in sex pheromone production in Bicyclus anynana butterflies.

PubMed

Dion, Emilie; Monteiro, Antónia; Yew, Joanne Y

2016-12-14

Phenotypic plasticity refers to the environmental control of phenotypes. Cues experienced during development (developmental plasticity) or during adulthood (acclimatization) can both affect adult phenotypes. Phenotypic plasticity has been described in many traits but examples of developmental plasticity in physiological traits, in particular, remain scarce. We examined developmental plasticity and acclimatization in pheromone production in the butterfly Bicyclus anynana in response to rearing temperature. B. anynana lives in the African tropics where warm rearing temperatures of the wet season produce active males that court and females that choose, whereas cooler temperatures of the dry season lead to choosy less active males and courting females. We hypothesized that if male pheromone production is costly, it should be reduced in the dry season form. After describing the ultrastructure of pheromone producing cells, we showed that dry season males produced significantly less sex pheromones than wet season males, partly due to acclimatization and partly due to developmental plasticity. Variation in levels of one of the compounds is associated with differential regulation of a pheromone biosynthetic enzyme gene. This plasticity might be an adaptation to minimize pheromone production costs during the stressful dry season.

Fouling assemblage of benthic plastic debris collected from Mersin Bay, NE Levantine coast of Turkey.

PubMed

Gündoğdu, Sedat; Çevik, Cem; Karaca, Serkan

2017-11-15

The Mediterranean is an ecosystem that faces more and more microplastic pollution every day. This causes the whole of the Mediterranean to face the negative effects of plastic pollution. This study examines the state of plastic debris and fouling organisms found on it in one of the areas most affected by plastic pollution, Mersin Bay. As a result, a total of 3.88kg plastic (mean=0,97kg; n=120; 2670item/km 2 ; 86,3kg/km 2 ) was collected and based on the ATR-FTIR analysis, it was determined that this total contained 9 types of plastics. 17 different fouling species belonging to 6 phylum (Annelida, Arthropoda, Bryozoa, Chordata, Cnidaria, Mollusca) 7 class and 11 order were discovered on plastics. Spirobranchus triqueter, Hydroides sp. and Neopycnodonte cochlear were the most abundant species. In the end, the example of Mersin Bay shows that plastic debris as a substrate can contain a very high diversity of life just like natural substrates. Copyright © 2017 Elsevier Ltd. All rights reserved.

Modeling somatic and dendritic spike mediated plasticity at the single neuron and network level.

PubMed

Bono, Jacopo; Clopath, Claudia

2017-09-26

Synaptic plasticity is thought to be the principal neuronal mechanism underlying learning. Models of plastic networks typically combine point neurons with spike-timing-dependent plasticity (STDP) as the learning rule. However, a point neuron does not capture the local non-linear processing of synaptic inputs allowed for by dendrites. Furthermore, experimental evidence suggests that STDP is not the only learning rule available to neurons. By implementing biophysically realistic neuron models, we study how dendrites enable multiple synaptic plasticity mechanisms to coexist in a single cell. In these models, we compare the conditions for STDP and for synaptic strengthening by local dendritic spikes. We also explore how the connectivity between two cells is affected by these plasticity rules and by different synaptic distributions. Finally, we show that how memory retention during associative learning can be prolonged in networks of neurons by including dendrites.Synaptic plasticity is the neuronal mechanism underlying learning. Here the authors construct biophysical models of pyramidal neurons that reproduce observed plasticity gradients along the dendrite and show that dendritic spike dependent LTP which is predominant in distal sections can prolong memory retention.

Evidence of selection on phenotypic plasticity and cost of plasticity in response to host-feeding sources in the major Chagas disease vector Triatoma infestans.

PubMed

Nattero, Julieta; Leonhard, Gustavo; Gürtler, Ricardo E; Crocco, Liliana B

2015-12-01

Phenotypic plasticity is the ability of a genotype to display alternative phenotypes in different environments. Understanding how plasticity evolves and the factors that favor and constrain its evolution have attracted great interest. We investigated whether selection on phenotypic plasticity and costs of plasticity affect head and wing morphology in response to host-feeding sources in the major Chagas disease vector Triatoma infestans. Full-sib families were assigned to blood-feeding on either live pigeons or guinea pigs throughout their lives. We measured diet-induced phenotypic plasticity on wing and head size and shape; characterized selection on phenotypic plasticity for female and male fecundity rates, and evaluated costs of plasticity. Wing size and shape variables exhibited significant differences in phenotypic plasticity associated with host-feeding source in female and male bugs. Evidence of selection on phenotypic plasticity was detected in head size and shape for guinea pig-fed females. A lower female fecundity rate was detected in more plastic families for traits that showed selection on plasticity. These results provide insights into the morphological phenotypic plasticity of T. infestans, documenting fitness advantages of head size and shape for females fed on guinea pigs. This vector species showed measurable benefits of responding plastically to environmental variation rather than adopting a fixed development plan. The presence of cost of plasticity suggests constraints on the evolution of plasticity. Our study indicates that females fed on guinea pigs (and perhaps on other suitable mammalian hosts) have greater chances of evolving under selection on phenotypic plasticity subject to some constraints. Copyright © 2015 Elsevier B.V. All rights reserved.

Plastics in the marine environment: the dark side of a modern gift.

PubMed

Hammer, Jort; Kraak, Michiel H S; Parsons, John R

2012-01-01

Plastics are cheap, strong, and durable and offer considerable benefits to humanity. They potentially can enhance the benefits that both medical and scientific technology will bestow to humankind. However, it has now been several decades since the use of plastics exploded, and we have evidence that our current approach to production, use, transport and disposal of plastic materials has caused, and is still causing serious effects on wildlife, and is not sustainable. Because of frequent inappropriate waste management practices, or irresponsible human behavior, large masses of plastic items have been released into the environment, and thereby have entered the world's oceans. Moreover, this process continues, and in some places is even increasing. Most plastic debris that now exists in the marine environment originated from ocean-based sources such as the fishing industry. Plastics accumulate in coastal areas, at the ocean surface and on the seabed. Because 70% of all plastics are known to eventually sink, it is suspected that ever increasing amounts of plastic items are accumulating in seabed sediments. Plastics do not biodegrade, although, under the influence of solar UV radiations, plastics do degrade and fragment into small particles, termed microplastics. Our oceans eventually serve as a sink for these small plastic particles and in one estimate, it is thought that 200,000 microplastics per km(2) of the ocean's surface commonly exist. The impact of plastic debris has been studied since the beginning of the 1960's. To date, more than 267 species in the marine environment are known to have been affected by plastic entanglement or ingestion. Marine mammals are among those species that are most affected by entanglement in plastic debris. By contrast, marine birds suffer the most from ingestion of plastics. Organisms can also be seriously absorbed by floating plastic debris, or the contaminants may derive from plastic additives that are leached to the environment. Recent studies emphasize the important role of microplastics as they are easily ingestible by small organisms, such as plankton species, and form a pathway for contaminants to enter the food web. Contaminants leached from plastics tend to bioaccumulate in those organisms that absorb them, and chemical concentrations are often higher at higher trophic levels. This causes a threat to the basis of every food web and can have serious and far-reaching effects, even on nonmarine species such as polar bears and humans, who consume marine-grown food. Therefore, resolving the plastic debris problem is important to human kind for two reasons: we are both creator, and victim of the plastic pollution problem. Solutions to the plastic debris problem can only be achieved through a combination of actions. Such actions include the following: Legislation against marine pollution by plastics must be enforced, recycling must be accentuated, alternatives (biodegradable) to current plastic products must be found, and clean-up of debris must proceed, if the marine plastic pollution problem is to eventually be resolved. Governments cannot accomplish this task on their own, and will need help and initiative from the public. Moreover, resolving this long-standing problem will require time, money, and energy from many individuals now living and those of future generations, if a safer and cleaner marine environment is to be achieved.

Modelling of Local Necking and Fracture in Aluminium Alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Achani, D.; Eriksson, M.; Hopperstad, O. S.

2007-05-17

Non-linear Finite Element simulations are extensively used in forming and crashworthiness studies of automotive components and structures in which fracture need to be controlled. For thin-walled ductile materials, the fracture-related phenomena that must be properly represented are thinning instability, ductile fracture and through-thickness shear instability. Proper representation of the fracture process relies on the accuracy of constitutive and fracture models and their parameters that need to be calibrated through well defined experiments. The present study focuses on local necking and fracture which is of high industrial importance, and uses a phenomenological criterion for modelling fracture in aluminium alloys. As anmore » accurate description of plastic anisotropy is important, advanced phenomenological constitutive equations based on the yield criterion YLD2000/YLD2003 are used. Uniaxial tensile tests and disc compression tests are performed for identification of the constitutive model parameters. Ductile fracture is described by the Cockcroft-Latham fracture criterion and an in-plane shear tests is performed to identify the fracture parameter. The reason is that in a well designed in-plane shear test no thinning instability should occur and it thus gives more direct information about the phenomenon of ductile fracture. Numerical simulations have been performed using a user-defined material model implemented in the general-purpose non-linear FE code LS-DYNA. The applicability of the model is demonstrated by correlating the predicted and experimental response in the in-plane shear tests and additional plane strain tension tests.« less

Cooler butterflies lay larger eggs: developmental plasticity versus acclimation.

PubMed Central

Fischer, Klaus; Eenhoorn, Evelien; Bot, Adriane N M; Brakefield, Paul M; Zwaan, Bas J

2003-01-01

We use a full factorial design to investigate the effects of maternal and paternal developmental temperature, as well as female oviposition temperature, on egg size in the butterfly Bicyclus anynana. Butterflies were raised at two different temperatures and mated in four possible sex-by-parental-temperature crosses. The mated females were randomly divided between high and low oviposition temperatures. On the first day after assigning the females to different temperatures, only female developmental temperature affected egg size. Females reared at the lower temperature laid larger eggs than those reared at a higher temperature. When eggs were measured again after an acclimation period of 10 days, egg size was principally determined by the prevailing temperature during oviposition, with females ovipositing at a lower temperature laying larger eggs. In contrast to widely used assumptions, the effects of developmental temperature were largely reversible. Male developmental temperature did not affect egg size in either of the measurements. Overall, developmental plasticity and acclimation in the adult stage resulted in very similar patterns of egg size plasticity. Consequently, we argue that the most important question when testing the significance of acclamatory changes is not at which stage a given plasticity is induced, but rather whether plastic responses to environmental change are adaptive or merely physiological constraints. PMID:14561294

Atomistic potentials based energy flux integral criterion for dynamic adiabatic shear banding

NASA Astrophysics Data System (ADS)

Xu, Yun; Chen, Jun

2015-02-01

The energy flux integral criterion based on atomistic potentials within the framework of hyperelasticity-plasticity is proposed for dynamic adiabatic shear banding (ASB). System Helmholtz energy decomposition reveals that the dynamic influence on the integral path dependence is originated from the volumetric strain energy and partial deviatoric strain energy, and the plastic influence only from the rest part of deviatoric strain energy. The concept of critical shear banding energy is suggested for describing the initiation of ASB, which consists of the dynamic recrystallization (DRX) threshold energy and the thermal softening energy. The criterion directly relates energy flux to the basic physical processes that induce shear instability such as dislocation nucleations and multiplications, without introducing ad-hoc parameters in empirical constitutive models. It reduces to the classical path independent J-integral for quasi-static loading and elastic solids. The atomistic-to-continuum multiscale coupling method is used to simulate the initiation of ASB. Atomic configurations indicate that DRX induced microstructural softening may be essential to the dynamic shear localization and hence the initiation of ASB.

Soft sediment deformation structures in the Maastrichtian Ajali Formation Western Flank of Anambra Basin, Southern Nigeria

NASA Astrophysics Data System (ADS)

Olabode, Solomon Ojo

2014-01-01

Soft sediment deformation structures were recognized in the Maastrichtian shallow marine wave to tide influenced regressive sediments of Ajali Formation in the western flank of Anambra basin, southern Nigerian. The soft sediment deformation structures were in association with cross bedded sands, clay and silt and show different morphological types. Two main types recognised are plastic deformations represented by different types of recumbent folds and injection structure represented by clastic dykes. Other structures in association with the plastic deformation structures include distorted convolute lamination, subsidence lobes, pillars, cusps and sand balls. These structures are interpreted to have been formed by liquefaction and fluidization mechanisms. The driving forces inferred include gravitational instabilities and hydraulic processes. Facies analysis, detailed morphologic study of the soft sediment deformation structures and previous tectonic history of the basin indicate that the main trigger agent for deformation is earthquake shock. The soft sediment deformation structures recognised in the western part of Anambra basin provide a continuous record of the tectonic processes that acted on the regressive Ajali Formation during the Maastrichtian.

Modelling of reactive fluid transport in deformable porous rocks

NASA Astrophysics Data System (ADS)

Yarushina, V. M.; Podladchikov, Y. Y.

2009-04-01

One outstanding challenge in geology today is the formulation of an understanding of the interaction between rocks and fluids. Advances in such knowledge are important for a broad range of geologic settings including partial melting and subsequent migration and emplacement of a melt into upper levels of the crust, or fluid flow during regional metamorphism and metasomatism. Rock-fluid interaction involves heat and mass transfer, deformation, hydrodynamic flow, and chemical reactions, thereby necessitating its consideration as a complex process coupling several simultaneous mechanisms. Deformation, chemical reactions, and fluid flow are coupled processes. Each affects the others. Special effort is required for accurate modelling of the porosity field through time. Mechanical compaction of porous rocks is usually treated under isothermal or isoentropic simplifying assumptions. However, joint consideration of both mechanical compaction and reactive porosity alteration requires somewhat greater than usual care about thermodynamic consistency. Here we consider the modelling of multi-component, multi-phase systems, which is fundamental to the study of fluid-rock interaction. Based on the conservation laws for mass, momentum, and energy in the form adopted in the theory of mixtures, we derive a thermodynamically admissible closed system of equations describing the coupling of heat and mass transfer, chemical reactions, and fluid flow in a deformable solid matrix. Geological environments where reactive transport is important are located at different depths and accordingly have different rheologies. In the near surface, elastic or elastoplastic properties would dominate, whereas viscoplasticity would have a profound effect deeper in the lithosphere. Poorly understood rheologies of heterogeneous porous rocks are derived from well understood processes (i.e., elasticity, viscosity, plastic flow, fracturing, and their combinations) on the microscale by considering a representative volume element and subsequent averaging of microscopic constitutive laws. Micromechanical and thermodynamic modelling is performed in such a way that the consistency of the obtained rheology and thermodynamically admissible closed system of equations with the exact Gassman's relationship and Terzaghi effective stress law in the simplified case of poroelasticity is guaranteed. In such environments as subduction zones or mid-ocean ridge, metamorphic rocks exhibit a lack of chemical homogenisation. Geochemistry suggests that in order to produce chemical heterogeneity, the fluids generated during high-pressure metamorphism must have been strongly channelled. The following three major mechanisms of fluid flow focusing have been proposed: fluid flow in open fractures and two different types of flow instabilities that do not require the pre-existing fracture network. Of the latter, the first represents a purely mechanical instability of Darcian flow through the deformable porous rock while the second is reactive infiltration instability. Both mechanical and reactive instabilities are expected to occur in the mantle and should probably reinforce each other. However, little research has been done in this direction. In order to investigate how the focusing of a fluid flow occurs, how mechanical and reactive infiltration instabilities influence each other, and what their relative importance in rocks with different rheologies is, linear and non-linear stability analysis is applied to derived governing equations.

Biologic and plastic effects of experimental traumatic brain injury treatment paradigms and their relevance to clinical rehabilitation

PubMed Central

Garcia, Alexandra N.; Shah, Mansi A.; Dixon, C. Edward; Wagner, Amy K.; Kline, Anthony E.

2011-01-01

Neuroplastic changes, whether induced by traumatic brain injury (TBI) or therapeutic interventions, alter neurobehavioral outcome. Here we present several treatment strategies that have been evaluated using experimental TBI models and discuss potential mechanisms of action (i.e., plasticity) and how such changes affect function. PMID:21703575

Repetitive Visual Stimulation Enhances Recovery from Severe Amblyopia

ERIC Educational Resources Information Center

Montey, Karen L.; Eaton, Nicolette C.; Quinlan, Elizabeth M.

2013-01-01

Severe amblyopia, characterized by a significant reduction in visual acuity through the affected eye, is highly resistant to reversal in adulthood. We have previously shown that synaptic plasticity can be reactivated in the adult rat visual cortex by dark exposure, and the reactivated plasticity can be harnessed to promote the recovery from severe…

Management of Bacterial Blight of Lilac Caused by Pseudomonas syringae by Growing Plants under Plastic Shelters

USDA-ARS?s Scientific Manuscript database

Pseudomonas syringae pv. syringae causes some of the most economically-important bacterial diseases affecting woody perennials grown by the nursery industry in the Pacific Northwest of the United States. In this study, we evaluated a cultural control practice, placement of plants in plastic shelter...

Scotblood 2007: Tackling local and global issues in transfusion medicine - donor recruitment, effective use of blood, stem cell plasticity, and vCJD.

PubMed

Bessos, Hagop; Fraser, Robin; Seghatchian, Jerard

2008-02-01

This commentary briefly highlights some of the local and the global contemporary issues affecting transfusion medicine worldwide. The main areas of focus addressed this year were: donor recruitment, stem cell plasticity, the effective use of blood, and vCJD.

Outcome after failed traumatic anterior shoulder instability repair with and without surgical revision.

PubMed

Marquardt, Björn; Garmann, Stefan; Schulte, Tobias; Witt, Kai-Axel; Steinbeck, Jörn; Pötzl, Wolfgang

2007-01-01

The purpose of this study was to evaluate the incidence and reasons of recurrent instability in patients with traumatic anterior shoulder instability and to document the clinical results with regard to the number of stabilizing procedures. Twenty-four patients with failed primary open or arthroscopic anterior shoulder stabilization were followed for a mean of 68 (36-114) months. Following recurrence of shoulder instability, eight patients chose not to be operated on again, whereas 16 underwent repeat stabilization. A persistent or recurrent Bankart lesion was found in all 16 patients and concomitant capsular redundancy in 4. After the first revision surgery, further instability occurred in 8 patients, and 6 of them were stabilized a third time. Only 7 patients (29%) achieved a good or excellent result according to the Rowe score. All shoulder scores improved after revision stabilization. However, the number of stabilizing procedures adversely affected the outcome scores, as well as postoperative range of motion and patient satisfaction. Recurrent instability after a primary stabilization procedure represents a difficult diagnostic and surgical challenge, and careful attention should be paid to address persistent or recurrent Bankart lesions and concomitant capsular reduncancy. A satisfying functional outcome can be expected mainly in patients with one revision surgery. Further stabilization attempts are associated with poorer objective and subjective results.

Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campioli, Enrico; Department of Medicine, McGill University, Montréal, Québec; Duong, Tam B.

Plastics are generally mixed with additives like plasticizers to enhance their flexibility, pliability, and elasticity proprieties. Plasticizers are easily released into the environment and are absorbed mainly through ingestion, dermal contact, and inhalation. One of the main classes of plasticizers, phthalates, has been associated with endocrine and reproductive diseases. In 2002, 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH) was introduced in the market for use in plastic materials and articles intended to come into contact with food, and it received final approval from the European Food Safety Authority in 2006. At present, there is limited knowledge about the safety and potentialmore » metabolic and endocrine-disrupting properties of DINCH and its metabolites. The purpose of this study was to evaluate the biological effects of DINCH and its active metabolites, cyclohexane-1,2-dicarboxylic acid (CHDA) and cyclohexane-1,2-dicarboxylic acid mono isononyl ester (MINCH), on rat primary stromal vascular fraction (SVF) of adipose tissue. DINCH and its metabolite, CHDA, were not able to directly affect SVF differentiation. However, exposure of SVF to 50 μM and 100 μM concentrations of MINCH affected the expression of Cebpa and Fabp4, thus inducing SVF preadipocytes to accumulate lipids and fully differentiate into mature adipocytes. The effect of MINCH was blocked by the specific peroxisome proliferator-activated receptor (PPAR)-α antagonist, GW6471. Taken together, these results suggest that MINCH is a potent PPAR-α agonist and a metabolic disruptor, capable of inducing SVF preadipocyte differentiation, that may interfere with the endocrine system in mammals. - Highlights: • DINCH and CHDA did not affect the adipogenesis of the SVF. • MINCH affected the adipogenesis of the SVF. • MINCH effect was blocked by the specific PPAR-α antagonist GW6471. • MINCH exerted a similar effect as MEHP on SVF adipogenesis. • DINCH/MINCH are potential metabolic disruptors.« less

Analysis of the influencing factors of PAEs volatilization from typical plastic products.

PubMed

Chen, Weidong; Chi, Chenchen; Zhou, Chen; Xia, Meng; Ronda, Cees; Shen, Xueyou

2018-04-01

The primary emphasis of this research was to investigate the foundations of phthalate (PAEs) pollutant source researches and then firstly confirmed the concept of the coefficient of volatile strength, namely phthalate total content in per unit mass and unit surface area of pollutant sources. Through surveying and evaluating the coefficient of volatile strength of PAEs from typical plastic products, this research carried out reasonable classification of PAEs pollutant sources into three categories and then investigated the relationship amongst the coefficient of volatile strength as well as other environmental factors and the concentration level of total PAEs in indoor air measured in environment chambers. Research obtained phthalate concentration results under different temperature, humidity, the coefficient of volatile strength and the closed time through the chamber experiment. In addition, this study further explored the correlation and ratio of influencing factors that affect the concentration level of total PAEs in environment chambers, including environmental factors, the coefficient of volatile strengths of PAEs and contents of total PAEs in plastic products. The research created an improved database system of phthalate the coefficient of volatile strengths of each type of plastic goods, and tentatively revealed that the volatile patterns of PAEs from different typical plastic goods, finally confirmed that the coefficient of volatile strengths of PAEs is a major factor that affects the indoor air total PAEs concentration, which laid a solid foundation for further establishing the volatile equation of PAEs from plastic products. Copyright © 2017. Published by Elsevier B.V.

Numerical studies of the Kelvin-Hemholtz instability in a coronal jet

NASA Astrophysics Data System (ADS)

Zhao, Tian-Le; Ni, Lei; Lin, Jun; Ziegler, Udo

2018-04-01

Kelvin-Hemholtz (K-H) instability in a coronal EUV jet is studied via 2.5D MHD numerical simulations. The jet results from magnetic reconnection due to the interaction of the newly emerging magnetic field and the pre-existing magnetic field in the corona. Our results show that the Alfvén Mach number along the jet is about 5–14 just before the instability occurs, and it is even higher than 14 at some local areas. During the K-H instability process, several vortex-like plasma blobs with high temperature and high density appear along the jet, and magnetic fields have also been rolled up and the magnetic configuration including anti-parallel magnetic fields forms, which leads to magnetic reconnection at many X-points and current sheet fragments inside the vortex-like blob. After magnetic islands appear inside the main current sheet, the total kinetic energy of the reconnection outflows decreases, and cannot support the formation of the vortex-like blob along the jet any longer, then the K-H instability eventually disappears. We also present the results about how the guide field and flux emerging speed affect the K-H instability. We find that a strong guide field inhibits shock formation in the reconnecting upward outflow regions but helps secondary magnetic islands appear earlier in the main current sheet, and then apparently suppresses the K-H instability. As the speed of the emerging magnetic field decreases, the K-H instability appears later, the highest temperature inside the vortex blob gets lower and the vortex structure gets smaller.

Near-Source Shaking and Dynamic Rupture in Plastic Media

NASA Astrophysics Data System (ADS)

Gabriel, A.; Mai, P. M.; Dalguer, L. A.; Ampuero, J. P.

2012-12-01

Recent well recorded earthquakes show a high degree of complexity at the source level that severely affects the resulting ground motion in near and far-field seismic data. In our study, we focus on investigating source-dominated near-field ground motion features from numerical dynamic rupture simulations in an elasto-visco-plastic bulk. Our aim is to contribute to a more direct connection from theoretical and computational results to field and seismological observations. Previous work showed that a diversity of rupture styles emerges from simulations on faults governed by velocity-and-state-dependent friction with rapid velocity-weakening at high slip rate. For instance, growing pulses lead to re-activation of slip due to gradual stress build-up near the hypocenter, as inferred in some source studies of the 2011 Tohoku-Oki earthquake. Moreover, off-fault energy dissipation implied physical limits on extreme ground motion by limiting peak slip rate and rupture velocity. We investigate characteristic features in near-field strong ground motion generated by dynamic in-plane rupture simulations. We present effects of plasticity on source process signatures, off-fault damage patterns and ground shaking. Independent of rupture style, asymmetric damage patterns across the fault are produced that contribute to the total seismic moment, and even dominantly at high angles between the fault and the maximum principal background stress. The off-fault plastic strain fields induced by transitions between rupture styles reveal characteristic signatures of the mechanical source processes during the transition. Comparing different rupture styles in elastic and elasto-visco-plastic media to identify signatures of off-fault plasticity, we find varying degrees of alteration of near-field radiation due to plastic energy dissipation. Subshear pulses suffer more peak particle velocity reduction due to plasticity than cracks. Supershear ruptures are affected even more. The occurrence of multiple rupture fronts affect seismic potency release rate, amplitude spectra, peak particle velocity distributions and near-field seismograms. Our simulations enable us to trace features of source processes in synthetic seismograms, for example exhibiting a re-activation of slip. Such physical models may provide starting points for future investigations of field properties of earthquake source mechanisms and natural fault conditions. In the long-term, our findings may be helpful for seismic hazard analysis and the improvement of seismic source models.

Lateral Patellar Instability in the Skeletally Mature Patient: Evaluation and Surgical Management.

PubMed

Diduch, David R; Kandil, Abdurrahman; Burrus, M Tyrrell

2018-05-18

Lateral patellar instability is a common disease process that affects all types of patients. Depending on the patient's anatomy and the results of preoperative imaging, surgical management options include medial patellofemoral ligament reconstruction, tibial tubercle osteotomy, and sulcus-deepening trochleoplasty. Medial patellofemoral ligament reconstruction or repair is useful for almost all patients, whereas tibial tubercle osteotomy is helpful to correct a lateralized tibial tubercle and the associated elevated lateral pull of the extensor mechanism. For a select subset of patients with severe trochlear dysplasia, a sulcus-deepening trochleoplasty can be a useful option to prevent future patellar instability. Many technical considerations exist for each procedure, and in most situations, no consensus exists to direct surgeons on the superior technique.

Interaction between emotional state and learning underlies mood instability

PubMed Central

Eldar, Eran; Niv, Yael

2015-01-01

Intuitively, good and bad outcomes affect our emotional state, but whether the emotional state feeds back onto the perception of outcomes remains unknown. Here, we use behaviour and functional neuroimaging of human participants to investigate this bidirectional interaction, by comparing the evaluation of slot machines played before and after an emotion-impacting wheel-of-fortune draw. Results indicate that self-reported mood instability is associated with a positive-feedback effect of emotional state on the perception of outcomes. We then use theoretical simulations to demonstrate that such positive feedback would result in mood destabilization. Taken together, our results suggest that the interaction between emotional state and learning may play a significant role in the emergence of mood instability. PMID:25608088

Thermal Recovery of Plastic Deformation in Dissimilar Metal Weld

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qiao, Dongxiao; Yu, Xinghua; Zhang, Wei

Stainless steel has been widely used in challenging environments typical to nuclear power plant structures, due its excellent corrosion resistance. Nickel filler metals containing high chromium concentration, including Alloy 82/182, are used for joining stainless steel to carbon steel components to achieve similar high resistance to stress corrosion cracking. However, the joint usually experience weld metal stress corrosion cracking (SCC), which affects the safety and structural integrity of light water nuclear reactor systems. A primary driving force for SCC is the high tensile residual stress in these welds. Due to large dimension of pressure vessel and limitations in the field,more » non-destructive residual stress measurement is difficult. As a result, finite element modeling has been the de facto method to evaluate the weld residual stresses. Recent studies on this subject from researchers worldwide report different residual stress value in the weldments [5]. The discrepancy is due to the fact that most of investigations ignore or underestimate the thermal recovery in the heat-affect zone or reheated region in the weld. In this paper, the effect of heat treatment on thermal recovery and microhardness is investigated for materials used in dissimilar metal joint. It is found that high equivalent plastic strains are predominately accumulated in the buttering layer, the root pass, and the heat affected zone, which experience multiple welding thermal cycles. The final cap passes, experiencing only one or two welding thermal cycles, exhibit less plastic strain accumulation. Moreover, the experimental residual plastic strains are compared with those predicted using an existing weld thermo-mechanical model with two different strain hardening rules. The importance of considering the dynamic strain hardening recovery due to high temperature exposure in welding is discussed for the accurate simulation of weld residual stresses and plastic strains. In conclsuion, the experimental result reveals that the typical post-buttering heat treatment for residual stress relief may not be adequate to completely eliminate the residual plastic strains in the buttering layer.« less

Plastic and Non-plastic Debris Ingestion in Three Gull Species Feeding in an Urban Landfill Environment.

PubMed

Seif, S; Provencher, J F; Avery-Gomm, S; Daoust, P-Y; Mallory, M L; Smith, P A

2018-04-01

Plastic debris is recognized as a widespread, common and problematic environmental pollutant. An important consequence of this pollution is the ingestion of plastic debris by wildlife. Assessing the degree to which different species ingest plastics, and the potential effects of these plastics on their health are important research needs for understanding the impacts of plastic pollution. We examined debris (plastic and other types) ingestion in three sympatric overwintering gull species (Herring gulls Larus smithsonianus, Great Black-backed Gulls Larus marinus, and Iceland Gulls Larus glaucoides) to understand how debris ingestion differs among species, age classes and sexes in gulls. We also assessed how plastic burdens were associated with body condition to investigate how gulls may be affected by debris ingestion. There were no differences among the species, age classes or sexes in the incidence of debris ingestion (plastic or otherwise), the mass or number of debris pieces ingested. We found no correlation between ingested plastics burdens and individual condition. Gulls ingested plastic debris, but also showed high levels of other debris types as well, including metal, glass and building materials, including a metal piece of debris found within an abscess in the stomach. Thus, when the health effects of debris ingestion on gulls, and other species that ingest debris, is of interest, either from a physical or chemical perspective, it may be necessary to consider all debris types and not just plastic burdens as is often currently done for seabirds.

Richtmyer-Meshkov instability for elastic-plastic solids in converging geometries

NASA Astrophysics Data System (ADS)

López Ortega, A.; Lombardini, M.; Barton, P. T.; Pullin, D. I.; Meiron, D. I.

2015-03-01

We present a detailed study of the interface instability that develops at the boundary between a shell of elastic-plastic material and a cylindrical core of confined gas during the inbound implosive motion generated by a shock-wave. The main instability in this configuration is the so-called Richtmyer-Meshkov instability that arises when the shock wave crosses the material interface. Secondary instabilities, such as Rayleigh-Taylor, due to the acceleration of the interface, and Kelvin-Helmholtz, due to slip between solid and fluid, arise as the motion progresses. The reflection of the shock wave at the axis and its second interaction with the material interface as the shock moves outbound, commonly known as re-shock, results in a second Richtmyer-Meshkov instability that potentially increases the growth rate of interface perturbations, resulting in the formation of a mixing zone typical of fluid-fluid configurations and the loss of the initial perturbation length scales. The study of this problem is of interest for achieving stable inertial confinement fusion reactions but its complexity and the material conditions produced by the implosion close to the axis prove to be challenging for both experimental and numerical approaches. In this paper, we attempt to circumvent some of the difficulties associated with a classical numerical treatment of this problem, such as element inversion in Lagrangian methods or failure to maintain the relationship between the determinant of the deformation tensor and the density in Eulerian approaches, and to provide a description of the different events that occur during the motion of the interface. For this purpose, a multi-material numerical solver for evolving in time the equations of motion for solid and fluid media in an Eulerian formalism has been implemented in a Cartesian grid. Equations of state are derived using thermodynamically consistent hyperelastic relations between internal energy and stresses. The resolution required for capturing the state of solid and fluid materials close to the origin is achieved by making use of adaptive mesh refinement techniques. Rigid-body rotations contained in the deformation tensor have been shown to have a negative effect on the accuracy of the method in extreme compression conditions and are removed by transforming the deformation tensor into a stretch tensor at each time step. With this methodology, the evolution of the interface can be tracked up to a point at which numerical convergence cannot be achieved due to the inception of numerical Kelvin-Helmholtz instabilities caused by slip between materials. From that point, only qualitative conclusions can be extracted from this analysis. The influence of different geometrical parameters, initial conditions, and material properties on the motion of the interface are investigated. Some major differences are found with respect to the better understood fluid-fluid case. For example, increasing the wave number of the interface perturbations leads to a second phase reversal of the interface (i.e., the first phase reversal of the interface naturally occurs due to the initial negative growth-rate of the instability as the shock wave transitions from the high-density material to the low-density one). This phenomenon is caused by the compressive effect of the converging geometry and the low density of the gas with respect to the solid, which allows for the formation of an incipient spike in the center of an already existing bubble. Multiple solid-gas density ratios are also considered. Results show that the motion of the interface asymptotically converges to the solid-vacuum case. When a higher initial density for the gas is considered, the growth rate of interface perturbations decreases and, in some situations, its sign may reverse, as the fluid becomes more dense than the solid due to having higher compressibility. Finally, the influence of the Mach number of the driving shock and the yield stress on the mixing-zone is examined. We find that the width of the mixing zone produced after the re-shock increases in proportion to the strength of the incident shock. An increased yield stress in the solid material makes the interface less unstable due to vorticity being carried away from the interface by shear waves and limits the generation of smaller length scales after the re-shock.

Modeling of dislocation channel width evolution in irradiated metals

DOE PAGES

Doyle, Peter J.; Benensky, Kelsa M.; Zinkle, Steven J.

2017-11-08

Defect-free dislocation channel formation has been reported to promote plastic instability during tensile testing via localized plastic flow, leading to a distinct loss of ductility and strain hardening in many low-temperature irradiated materials. In order to study the underlying mechanisms governing dislocation channel width and formation, the channel formation process is modeled via a simple stochastic dislocation-jog process dependent upon grain size, defect cluster density, and defect size. Dislocations traverse a field of defect clusters and jog stochastically upon defect interaction, forming channels of low defect-density. And based upon prior molecular dynamics (MD) simulations and in-situ experimental transmission electron microscopymore » (TEM) observations, each dislocation encounter with a dislocation loop or stacking fault tetrahedron (SFT) is assumed to cause complete absorption of the defect cluster, prompting the dislocation to jog up or down by a distance equal to half the defect cluster diameter. Channels are predicted to form rapidly and are comparable to reported TEM measurements for many materials. Predicted channel widths are found to be most strongly dependent on mean defect size and correlated well with a power law dependence on defect diameter and density, and distance from the dislocation source. Due to the dependence of modeled channel width on defect diameter and density, maximum channel width is predicted to slowly increase as accumulated dose increases. The relatively weak predicted dependence of channel formation width with distance, in accordance with a diffusion analogy, implies that after only a few microns from the source, most channels observed via TEM analyses may not appear to vary with distance because of limitations in the field-of-view to a few microns. Furthermore, examinations of the effect of the so-called “source-broadening” mechanism of channel formation showed that its effect is simply to add a minimum thickness to the channel without affecting channel dependence on the given parameters.« less

Dynamic Hebbian Cross-Correlation Learning Resolves the Spike Timing Dependent Plasticity Conundrum.

PubMed

Olde Scheper, Tjeerd V; Meredith, Rhiannon M; Mansvelder, Huibert D; van Pelt, Jaap; van Ooyen, Arjen

2017-01-01

Spike Timing-Dependent Plasticity has been found to assume many different forms. The classic STDP curve, with one potentiating and one depressing window, is only one of many possible curves that describe synaptic learning using the STDP mechanism. It has been shown experimentally that STDP curves may contain multiple LTP and LTD windows of variable width, and even inverted windows. The underlying STDP mechanism that is capable of producing such an extensive, and apparently incompatible, range of learning curves is still under investigation. In this paper, it is shown that STDP originates from a combination of two dynamic Hebbian cross-correlations of local activity at the synapse. The correlation of the presynaptic activity with the local postsynaptic activity is a robust and reliable indicator of the discrepancy between the presynaptic neuron and the postsynaptic neuron's activity. The second correlation is between the local postsynaptic activity with dendritic activity which is a good indicator of matching local synaptic and dendritic activity. We show that this simple time-independent learning rule can give rise to many forms of the STDP learning curve. The rule regulates synaptic strength without the need for spike matching or other supervisory learning mechanisms. Local differences in dendritic activity at the synapse greatly affect the cross-correlation difference which determines the relative contributions of different neural activity sources. Dendritic activity due to nearby synapses, action potentials, both forward and back-propagating, as well as inhibitory synapses will dynamically modify the local activity at the synapse, and the resulting STDP learning rule. The dynamic Hebbian learning rule ensures furthermore, that the resulting synaptic strength is dynamically stable, and that interactions between synapses do not result in local instabilities. The rule clearly demonstrates that synapses function as independent localized computational entities, each contributing to the global activity, not in a simply linear fashion, but in a manner that is appropriate to achieve local and global stability of the neuron and the entire dendritic structure.

Modeling of dislocation channel width evolution in irradiated metals

NASA Astrophysics Data System (ADS)

Doyle, Peter J.; Benensky, Kelsa M.; Zinkle, Steven J.

2018-02-01

Defect-free dislocation channel formation has been reported to promote plastic instability during tensile testing via localized plastic flow, leading to a distinct loss of ductility and strain hardening in many low-temperature irradiated materials. In order to study the underlying mechanisms governing dislocation channel width and formation, the channel formation process is modeled via a simple stochastic dislocation-jog process dependent upon grain size, defect cluster density, and defect size. Dislocations traverse a field of defect clusters and jog stochastically upon defect interaction, forming channels of low defect-density. Based upon prior molecular dynamics (MD) simulations and in-situ experimental transmission electron microscopy (TEM) observations, each dislocation encounter with a dislocation loop or stacking fault tetrahedron (SFT) is assumed to cause complete absorption of the defect cluster, prompting the dislocation to jog up or down by a distance equal to half the defect cluster diameter. Channels are predicted to form rapidly and are comparable to reported TEM measurements for many materials. Predicted channel widths are found to be most strongly dependent on mean defect size and correlated well with a power law dependence on defect diameter and density, and distance from the dislocation source. Due to the dependence of modeled channel width on defect diameter and density, maximum channel width is predicted to slowly increase as accumulated dose increases. The relatively weak predicted dependence of channel formation width with distance, in accordance with a diffusion analogy, implies that after only a few microns from the source, most channels observed via TEM analyses may not appear to vary with distance because of limitations in the field-of-view to a few microns. Further, examinations of the effect of the so-called "source-broadening" mechanism of channel formation showed that its effect is simply to add a minimum thickness to the channel without affecting channel dependence on the given parameters.

Modeling of dislocation channel width evolution in irradiated metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doyle, Peter J.; Benensky, Kelsa M.; Zinkle, Steven J.

Defect-free dislocation channel formation has been reported to promote plastic instability during tensile testing via localized plastic flow, leading to a distinct loss of ductility and strain hardening in many low-temperature irradiated materials. In order to study the underlying mechanisms governing dislocation channel width and formation, the channel formation process is modeled via a simple stochastic dislocation-jog process dependent upon grain size, defect cluster density, and defect size. Dislocations traverse a field of defect clusters and jog stochastically upon defect interaction, forming channels of low defect-density. And based upon prior molecular dynamics (MD) simulations and in-situ experimental transmission electron microscopymore » (TEM) observations, each dislocation encounter with a dislocation loop or stacking fault tetrahedron (SFT) is assumed to cause complete absorption of the defect cluster, prompting the dislocation to jog up or down by a distance equal to half the defect cluster diameter. Channels are predicted to form rapidly and are comparable to reported TEM measurements for many materials. Predicted channel widths are found to be most strongly dependent on mean defect size and correlated well with a power law dependence on defect diameter and density, and distance from the dislocation source. Due to the dependence of modeled channel width on defect diameter and density, maximum channel width is predicted to slowly increase as accumulated dose increases. The relatively weak predicted dependence of channel formation width with distance, in accordance with a diffusion analogy, implies that after only a few microns from the source, most channels observed via TEM analyses may not appear to vary with distance because of limitations in the field-of-view to a few microns. Furthermore, examinations of the effect of the so-called “source-broadening” mechanism of channel formation showed that its effect is simply to add a minimum thickness to the channel without affecting channel dependence on the given parameters.« less

The Thermal and Microstructural Effect of Plasticizing HMX-Nitrocellulose Composites

DOE PAGES

Yeager, John David; Watkins, Erik Benjamin; Duque, Amanda Lynn; ...

2017-03-15

Thermal ignition via self-heating (cook-off) of cyclotetramethylene-tetranitramine (HMX)-containing plastic-bonded explosives (PBXs) is driven by the β → δ phase transition in the HMX, which is affected if not dominated by microstructure. Here, we studied the HMX-binder interface and phase transition for several variations of PBX 9404 (HMX with plasticized nitrocellulose [NC] binder). Neutron reflectometry was used to examine the interface under several conditions—pristine, after aging, and after thermal treatment. The initial interfacial structure depended on the plasticizer, but the interface homogenized over time. Thermal and optical analyses showed that all formulated materials had higher transition temperatures than neat HMX. Thismore » effect increased with NC content.« less

Phenotypic plasticity and longevity in plants and animals: cause and effect?

PubMed

Borges, Renee M

2009-10-01

Immobile plants and immobile modular animals outlive unitary animals. This paper discusses competing but not necessarily mutually exclusive theories to explain this extreme longevity, especially from the perspective of phenotypic plasticity. Stem cell immortality, vascular autonomy, and epicormic branching are some important features of the phenotypic plasticity of plants that contribute to their longevity. Monocarpy versus polycarpy can also influence the kind of senescent processes experienced by plants. How density-dependent phenomena affecting the establishment of juveniles in these immobile organisms can influence the evolution of senescence, and consequently longevity, is reviewed and discussed. Whether climate change scenarios will favour long-lived or short-lived organisms, with their attendant levels of plasticity, is also presented.

A physicochemical study of sugar palm (Arenga Pinnata) starch films plasticized by glycerol and sorbitol

NASA Astrophysics Data System (ADS)

Poeloengasih, Crescentiana D.; Pranoto, Yudi; Hayati, Septi Nur; Hernawan, Rosyida, Vita T.; Prasetyo, Dwi J.; Jatmiko, Tri H.; Apriyana, Wuri; Suwanto, Andri

2016-02-01

The present work explores the physicochemical characteristics of sugar palm starch film for a potential hard capsule purpose. Sugar palm (Arenga pinnata) starch films were plasticized with glycerol or sorbitol in various concentrations (30% up to 50% w/w starch). Their effects on physicochemical properties of the films were investigated. The results showed that sugar palm starch was successfully developed as the main material of film using casting method. Incorporation of both glycerol or sorbitol affected the properties of films in different ways. It was found that thickness and solubility increased as plasticizer concentration increased, whereas retraction ratio, swelling degree and swelling thickness decreased with the increased plasticizer concentration.

The Thermal and Microstructural Effect of Plasticizing HMX-Nitrocellulose Composites

NASA Astrophysics Data System (ADS)

Yeager, John D.; Watkins, Erik B.; Higginbotham Duque, Amanda L.; Majewski, Jaroslaw

2018-01-01

Thermal ignition via self-heating (cook-off) of cyclotetramethylene-tetranitramine (HMX)-containing plastic-bonded explosives (PBXs) is driven by the β → δ phase transition in the HMX, which is affected if not dominated by microstructure. Here, the HMX-binder interface and phase transition were studied for several variations of PBX 9404 (HMX with plasticized nitrocellulose [NC] binder). Neutron reflectometry was used to examine the interface under several conditions-pristine, after aging, and after thermal treatment. The initial interfacial structure depended on the plasticizer, but the interface homogenized over time. Thermal and optical analyses showed that all formulated materials had higher transition temperatures than neat HMX. This effect increased with NC content.

Folding and Boudinage As the Same Fundamental Energy Bifurcation in Elasto-Visco-Plastic Rocks

NASA Astrophysics Data System (ADS)

Peters, M.; Paesold, M.; Veveakis, M.; Poulet, T.; Herwegh, M.; Regenauer-Lieb, K.

2014-12-01

Folding or boudinage are commonly thought to develop due to viscosity contrasts induced by either geometric interactions or material imperfections. However, there exists an additional localization phenomenon, i.e. strain localization out of steady state in homogeneous materials at a critical material parameter (set) or deformation rate. This study focuses on imperfections in terms of grain size variations, using the paleowattmeter relationship [Austin and Evans, 2007; 2009, Herwegh et al., 2014]. We identify the parameters for bifurcation, which is the critical amount of dissipation, expressed by the Gruntfest number [Gruntfest, 1963], incorporating flow stress, the Arrhenius number (Q/RT) and the layer dimensions. We verify the robustness of the solution through a method, developed to analyze such material instabilities [Rudnicki and Rice, 1975]. The second step is to identify the natural mode shapes and frequencies of the geometric structure and material parameters, including geometric imperfections. In a third step, the eigenmodes are perturbed and superposed to the initial conditions. We then subject the composite structure to natural deformation conditions. Grain sizes within the layer relatively quickly equilibrate to a homogeneous state, which is in response to energy optimization following the paleowattmeterrelationship. Upon continued loading, localization in terms of a necking or folding instability consequently arises out of this steady state. We obtain the criteria for the onset of localization from theory and numerical simulation, i.e. the critical Gruntfest number. Boudinage and folding instabilities occur when heat produced by dissipative work overcomes the diffusive capacity of the system. Both instabilities develop for the exact same Arrhenius and Gruntfestnumbers. Consequently, folding and boudinage instabilities can be seen as the same energy bifurcation triggered by dissipative work out of homogeneous state. Austin, N.J. and Evans, B. (2007) Geology, 35Austin, N.J. and Evans, B. (2009) Journal of Geophysical Research, 114Gruntfest, I.J. (1963) Transactions of the Society of Rheology, 7Herwegh, M., Poulet, T., Karrech, A. and Regenauer-Lieb, K. (2014) Journal of Geophysical Research, 119Rudnicki, J.W. and Rice, J.R. (1975) Journal of Mechanics and Physics of Solids, 23

Synthetic polymers in the marine environment: a rapidly increasing, long-term threat.

PubMed

Moore, Charles James

2008-10-01

Synthetic polymers, commonly known as plastics, have been entering the marine environment in quantities paralleling their level of production over the last half century. However, in the last two decades of the 20th Century, the deposition rate accelerated past the rate of production, and plastics are now one of the most common and persistent pollutants in ocean waters and beaches worldwide. Thirty years ago the prevailing attitude of the plastic industry was that "plastic litter is a very small proportion of all litter and causes no harm to the environment except as an eyesore" [Derraik, J.G.B., 2002. The pollution of the marine environment by plastic debris: a review. Mar. Pollut. Bull. 44(9), 842-852]. Between 1960 and 2000, the world production of plastic resins increased 25-fold, while recovery of the material remained below 5%. Between 1970 and 2003, plastics became the fastest growing segment of the US municipal waste stream, increasing nine-fold, and marine litter is now 60-80% plastic, reaching 90-95% in some areas. While undoubtedly still an eyesore, plastic debris today is having significant harmful effects on marine biota. Albatross, fulmars, shearwaters and petrels mistake floating plastics for food, and many individuals of these species are affected; in fact, 44% of all seabird species are known to ingest plastic. Sea turtles ingest plastic bags, fishing line and other plastics, as do 26 species of cetaceans. In all, 267 species of marine organisms worldwide are known to have been affected by plastic debris, a number that will increase as smaller organisms are assessed. The number of fish, birds, and mammals that succumb each year to derelict fishing nets and lines in which they become entangled cannot be reliably known; but estimates are in the millions. We divide marine plastic debris into two categories: macro, >5 mm and micro, <5 mm. While macro-debris may sometimes be traced to its origin by object identification or markings, micro-debris, consisting of particles of two main varieties, (1) fragments broken from larger objects, and (2) resin pellets and powders, the basic thermoplastic industry feedstocks, are difficult to trace. Ingestion of plastic micro-debris by filter feeders at the base of the food web is known to occur, but has not been quantified. Ingestion of degraded plastic pellets and fragments raises toxicity concerns, since plastics are known to adsorb hydrophobic pollutants. The potential bioavailability of compounds added to plastics at the time of manufacture, as well as those adsorbed from the environment are complex issues that merit more widespread investigation. The physiological effects of any bioavailable compounds desorbed from plastics by marine biota are being directly investigated, since it was found 20 years ago that the mass of ingested plastic in Great Shearwaters was positively correlated with PCBs in their fat and eggs. Colonization of plastic marine debris by sessile organisms provides a vector for transport of alien species in the ocean environment and may threaten marine biodiversity. There is also potential danger to marine ecosystems from the accumulation of plastic debris on the sea floor. The accumulation of such debris can inhibit gas exchange between the overlying waters and the pore waters of the sediments, and disrupt or smother inhabitants of the benthos. The extent of this problem and its effects have recently begun to be investigated. A little more than half of all thermoplastics will sink in seawater.

Processing and characterization of solid and microcellular biobased and biodegradable PHBV-based polymer blends and composites

NASA Astrophysics Data System (ADS)

Javadi, Alireza

Petroleum-based polymers have made a significant contribution to human society due to their extraordinary adaptability and processability. However, due to the wide-spread application of plastics over the past few decades, there are growing concerns over depleting fossil resources and the undesirable environmental impact of plastics. Most of the petroleum-based plastics are non-biodegradable and thus will be disposed in landfills. Inappropriate disposal of plastics may also become a potential threat to the environment. Many approaches, such as efficient plastics waste management and replacing petroleum-based plastics with biodegradable materials obtained from renewable resources, have been put forth to overcome these problems. Plastics waste management is at its beginning stages of development which is also more expensive than expected. Thus, there is a growing interest in developing sustainable biobased and biodegradable materials produced from renewable resources such as plants and crops, which can offer comparable performance with additional advantages, such as biodegradability, biocompatibility, and reducing the carbon footprint. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is one of the most promising biobased and biodegradable polymers, In fact many petroleum based polymers such as poly(propylene) (PP) can be potentially replaced by PHBV because of the similarity in their properties. Despite PHBV's attractive properties, there are many drawbacks such as high cost, brittleness, and thermal instability, which hamper the widespread usage of this specific polymer. The goals of this study are to investigate various strategies to address these drawbacks, including blending with other biodegradable polymers such as poly (butylene adipate-coterephthalate) (PBAT) or fillers (e.g., coir fiber, recycled wood fiber, and nanofillers) and use of novel processing technologies such as microcellular injection molding technique. Microcellular injection molding technique will not only reduce cost but also improve processability due to the use of supercritical fluid. Various material properties of the solid (without the foaming agent) and microcellular components (with foaming agent) made of PHBV-based polymer blends or composites were investigated including static mechanical properties (tensile testing), dynamic mechanical properties (dynamic mechanical analysis), thermal properties (differential scanning calorimetry and thermo gravimetric analysis), crystallinity(wide angle X-ray scattering analysis), and morphology (scanning electron microscopy and transmission electron microscopy). The composition-processing-structure-property relationship of these solid and microcellular components were established.

A connection between mix and adiabat in ICF capsules

NASA Astrophysics Data System (ADS)

Cheng, Baolian; Kwan, Thomas; Wang, Yi-Ming; Yi, Sunghuan (Austin); Batha, Steven

2016-10-01

We study the relationship between instability induced mix, preheat and the adiabat of the deuterium-tritium (DT) fuel in fusion capsule experiments. Our studies show that hydrodynamic instability not only directly affects the implosion, hot spot shape and mix, but also affects the thermodynamics of the capsule, such as, the adiabat of the DT fuel, and, in turn, affects the energy partition between the pusher shell (cold DT) and the hot spot. It was found that the adiabat of the DT fuel is sensitive to the amount of mix caused by Richtmyer-Meshkov (RM) and Rayleigh-Taylor (RT) instabilities at the material interfaces due to its exponential dependence on the fuel entropy. An upper limit of mix allowed maintaining a low adiabat of DT fuel is derived. Additionally we demonstrated that the use of a high adiabat for the DT fuel in theoretical analysis and with the aid of 1D code simulations could explain some aspects of the 3D effects and mix in the capsule experiments. Furthermore, from the observed neutron images and our physics model, we could infer the adiabat of the DT fuel in the capsule and determine the possible amount of mix in the hot spot (LA-UR-16-24880). This work was conducted under the auspices of the U.S. Department of Energy by the Los Alamos National Laboratory under Contract No. W-7405-ENG-36.

BDNF and LTP-/LTD-like plasticity of the primary motor cortex in Gilles de la Tourette syndrome.

PubMed

Marsili, L; Suppa, A; Di Stasio, F; Belvisi, D; Upadhyay, N; Berardelli, I; Pasquini, M; Petrucci, S; Ginevrino, M; Fabbrini, G; Cardona, F; Defazio, G; Berardelli, A

2017-03-01

Gilles de la Tourette syndrome (GTS) is characterized by motor and vocal tics and often associated with obsessive-compulsive disorder (OCD). Responses to intermittent/continuous theta-burst stimulation (iTBS/cTBS), which probe long-term potentiation (LTP)-/depression (LTD)-like plasticity in the primary motor cortex (M1), are reduced in GTS. ITBS-/cTBS-induced M1 plasticity can be affected by brain-derived neurotrophic factor (BDNF) polymorphism. We investigated whether the BDNF polymorphism influences iTBS-/cTBS-induced LTP-/LTD-like M1 plasticity in 50 GTS patients and in 50 age- and sex-matched healthy subjects. In GTS patients, motor and psychiatric (OCD) symptom severity was rated using the Yale Global Tic Severity Scale (YGTSS) and the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). We compared M1 iTBS-/cTBS-induced plasticity in healthy subjects and in patients with GTS. We also compared responses to TBS according to BDNF polymorphism (Val/Val vs Met carriers) in patients and controls. Fourteen healthy subjects and 13 GTS patients were Met carriers. When considering the whole group of controls, as expected, iTBS increased whereas cTBS decreased MEPs. Differently, iTBS/cTBS failed to induce LTP-/LTD-like plasticity in patients with GTS. When comparing responses to TBS according to BDNF polymorphism, in healthy subjects, Met carriers showed reduced MEP changes compared with Val/Val individuals. Conversely, in patients with GTS, responses to iTBS/cTBS were comparable in Val/Val individuals and Met carriers. YGTSS and Y-BOCS scores were comparable in Met carriers and in Val/Val subjects. We conclude that iTBS and cTBS failed to induce LTP-/LTD-like plasticity in patients with GTS, and this was not affected by BDNF genotype.

Foraging modality and plasticity in foraging traits determine the strength of competitive interactions among carnivorous plants, spiders and toads.

PubMed

Jennings, David E; Krupa, James J; Rohr, Jason R

2016-07-01

Foraging modalities (e.g. passive, sit-and-wait, active) and traits are plastic in some species, but the extent to which this plasticity affects interspecific competition remains unclear. Using a long-term laboratory mesocosm experiment, we quantified competition strength and the plasticity of foraging traits in a guild of generalist predators of arthropods with a range of foraging modalities. Each mesocosm contained eight passively foraging pink sundews, and we employed an experimental design where treatments were the presence or absence of a sit-and-wait foraging spider and actively foraging toad crossed with five levels of prey abundance. We hypothesized that actively foraging toads would outcompete the other species at low prey abundance, but that spiders and sundews would exhibit plasticity in foraging traits to compensate for strong competition when prey were limited. Results generally supported our hypotheses. Toads had a greater effect on sundews at low prey abundances, and toad presence caused spiders to locate webs higher above the ground. Additionally, the closer large spider webs were to the ground, the greater the trichome densities produced by sundews. Also, spider webs were larger with than without toads and as sundew numbers increased, and these effects were more prominent as resources became limited. Finally, spiders negatively affected toad growth only at low prey abundance. These findings highlight the long-term importance of foraging modality and plasticity of foraging traits in determining the strength of competition within and across taxonomic kingdoms. Future research should assess whether plasticity in foraging traits helps to maintain coexistence within this guild and whether foraging modality can be used as a trait to reliably predict the strength of competitive interactions. © 2016 The Authors. Journal of Animal Ecology © 2016 British Ecological Society.

Waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water near Elkhart, Indiana, 2000-2002.

PubMed

Buszka, P M; Yeskis, D J; Kolpin, D W; Furlong, E T; Zaugg, S D; Meyer, M T

2009-06-01

Four wells downgradient from a landfill near Elkhart, Indiana were sampled during 2000-2002 to evaluate the presence of waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water. Compounds detected in leachate-affected ground water included detergent metabolites (p-nonylphenol, nonylphenol monoethoxylate, nonylphenol diethoxylate, and octylphenol monoethoxylate), plasticizers (ethanol-2-butoxy-phosphate and diethylphthalate), a plastic monomer (bisphenol A), disinfectants (1,4-dichlorobenzene and triclosan), an antioxidant (5-methyl-1H-benzotriazole), three fire-retardant compounds (tributylphosphate and tri(2-chloroethyl)phosphate, and tri(dichlorisopropyl)phosphate), and several pharmaceuticals and metabolites (acetaminophen, caffeine, cotinine, 1,7-dimethylxanthine, fluoxetine, and ibuprofen). Acetaminophen, caffeine, and cotinine detections confirm prior indications of pharmaceutical and nicotinate disposal in the landfill.

Performance comparison of plastic shopping bags in modern and traditional retail

NASA Astrophysics Data System (ADS)

Radini, F. A.; Wulandari, R.; Nasiri, S. J. A.; Winarto, D. A.

2017-07-01

Followed by implementation of paid plastic bag policy in Indonesia’s modern and traditional retail, community question related to plastic shopping bag performance arise. But, there is limited information about it. Therefore, the assessment of the performance to compare between plastic shopping bags in modern retail and traditional retail should be interesting. The observation performance of plastic shopping bag were weight holding capacity, tear resistant and elongation. This performance were tested using Universal Testing Machine. Physical and physico-chemical properties also identified to determine factor affecting the performance of plastic shopping bag. The physical properties were analysed using visual and thickness gauge to see the colour and measure the thickness. The analysis of physico-chemical properties were carried out using DSC (Differential Scanning Calorimetry), TGA (Thermal Gravimetry Analysis), Furnace and FTIR (Fourier Transform Infra Red Spectroscopy) to identify the materials, also its melting and decomposition temperature. The result showed that the performance difference between modern retail plastic bag with traditional retail plastic bag appears only in the performance of elongation. The elongation of modern retail plastic bag is 121 - 413%, while traditional has 170 - 609%. According to physico-chemical test result, modern retail and traditional retail plastic bag contain polyethylene as main material and has melting temperature in the range of High Density Polyethylene (HDPE) melting temperature. However, modern retail plastic bag has 18.31 - 33.87% of inorganic filler percentage, whereas the traditional retail plastic bag has 0.35 - 9.85%. This inorganic filler percentage probably a contributing factor in the elongation performance difference between modern retail plastic bag with traditional retail plastic bag.

Continuous microcellular foaming of polylactic acid/natural fiber composites

NASA Astrophysics Data System (ADS)

Diaz-Acosta, Carlos A.

Poly(lactic acid) (PLA), a biodegradable thermoplastic derived from renewable resources, stands out as a substitute to petroleum-based plastics. In spite of its excellent properties, commercial applications are limited because PLA is more expensive and more brittle than traditional petroleum-based resins. PLA can be blended with cellulosic fibers to reduce material cost. However, the lowered cost comes at the expense of flexibility and impact strength, which can be enhanced through the production of microcellular structures in the composite. Microcellular foaming uses inert gases (e.g., carbon dioxide) as physical blowing agents to make cellular structures with bubble sizes of less than 10 microm and cell-population densities (number of bubbles per unit volume) greater than 109 cells/cm³. These unique characteristics result in a significant increase in toughness and elongation at break (ductility) compared with unfoamed parts because the presence of small bubbles can blunt the crack-tips increasing the energy needed to propagate the crack. Microcellular foams have been produced through a two step batch process. First, large amounts of gas are dissolved in the solid plastic under high pressure (sorption process) to form a single-phase solution. Second, a thermodynamic instability (sudden drop in solubility) triggers cell nucleation and growth as the gas diffuses out of the plastic. Batch production of microcellular PLA has addressed some of the drawbacks of PLA. Unfortunately, the batch foaming process is not likely to be implemented in the industrial production of foams because it is not cost-effective. This study investigated the continuous microcellular foaming process of PLA and PLA/wood-fiber composites. The effects of the processing temperature and material compositions on the melt viscosity, pressure drop rate, and cell-population density were examined in order to understand the nucleation mechanisms in neat and filled PLA foams. The results indicated that the processing temperature had a strong effect of the rheology of the melt and cell morphology. Processing at a lower temperature significantly increased the cell nucleation rate of neat PLA (amorphous and semi-crystalline) because of the fact that a high melt viscosity induced a high pressure drop rate in the polymer/gas solution. The presence of nanoclay did not affect the homogeneous nucleation but increased the heterogeneous nucleation, allowing both nucleation mechanisms to occur during the foaming process. The effect of wood-flour (0-30 wt.%) and rheology modifier contents on the melt viscosity and cell morphology of microcellular foamed composites was investigated. The viscosity of the melt increased with wood-flour content and decreased with rheology modifier content, affecting the processing conditions (i.e., pressure drop and pressure drop rate) and foamability of the composites. Matching the viscosity of the composites with that of neat PLA resulted in the best cell morphologies. Physico-mechanical characterization of microcellular foamed PLA as a function of cell morphology was performed to establish process-morphology-property relationships. The processing variables, i.e., amount of gas injected, flow rate, and processing temperature affected the development of the cellular structure and mechanical properties of the foams.

Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats

PubMed Central

Barmashenko, Gleb; Buttgereit, Jens; Herring, Neil; Bader, Michael; Özcelik, Cemil; Manahan-Vaughan, Denise; Braunewell, Karl H.

2014-01-01

The second messenger cyclic GMP affects synaptic transmission and modulates synaptic plasticity and certain types of learning and memory processes. The impact of the natriuretic peptide receptor B (NPR-B) and its ligand C-type natriuretic peptide (CNP), one of several cGMP producing signaling systems, on hippocampal synaptic plasticity and learning is, however, less well understood. We have previously shown that the NPR-B ligand CNP increases the magnitude of long-term depression (LTD) in hippocampal area CA1, while reducing the induction of long-term potentiation (LTP). We have extended this line of research to show that bidirectional plasticity is affected in the opposite way in rats expressing a dominant-negative mutant of NPR-B (NSE-NPR-BΔKC) lacking the intracellular guanylyl cyclase domain under control of a promoter for neuron-specific enolase. The brain cells of these transgenic rats express functional dimers of the NPR-B receptor containing the dominant-negative NPR-BΔKC mutant, and therefore show decreased CNP-stimulated cGMP-production in brain membranes. The NPR-B transgenic rats display enhanced LTP but reduced LTD in hippocampal slices. When the frequency-dependence of synaptic modification to afferent stimulation in the range of 1–100 Hz was assessed in transgenic rats, the threshold for both, LTP and LTD induction, was shifted to lower frequencies. In parallel, NPR-BΔKC rats exhibited an enhancement in exploratory and learning behavior. These results indicate that bidirectional plasticity and learning and memory mechanism are affected in transgenic rats expressing a dominant-negative mutant of NPR-B. Our data substantiate the hypothesis that NPR-B-dependent cGMP signaling has a modulatory role for synaptic information storage and learning. PMID:25520616

Development, fabrication and testing of a magnetically connected plastic vacuum probe surface sampler

NASA Technical Reports Server (NTRS)

Phillips, G. B.; Pace, V. A., Jr.

1972-01-01

The sampler utilizes permanent magnets and soft metal pole pieces to connect the cone/filter assembly to the sampling head and vacuum supply. The cone/filter assembly is packaged in a plastic container and presterilized so that the need for any human contact during the sampling procedure is completely eliminated. Microbiological tests have demonstrated that the sampling efficiency is not affected by the magnetic coupling apparatus and that the probe appears to function as efficiently as the conventional plastic and Sandia vacuum probes.

Modeling of surface effects in crystalline materials within the framework of gradient crystal plasticity

NASA Astrophysics Data System (ADS)

Peng, Xiang-Long; Husser, Edgar; Huang, Gan-Yun; Bargmann, Swantje

2018-03-01

A finite-deformation gradient crystal plasticity theory is developed, which takes into account the interaction between dislocations and surfaces. The model captures both energetic and dissipative effects for surfaces penetrable by dislocations. By taking advantage of the principle of virtual power, the surface microscopic boundary equations are obtained naturally. Surface equations govern surface yielding and hardening. A thin film under shear deformation serves as a benchmark problem for validation of the proposed model. It is found that both energetic and dissipative surface effects significantly affect the plastic behavior.

Induced sensorimotor brain plasticity controls pain in phantom limb patients

PubMed Central

Yanagisawa, Takufumi; Fukuma, Ryohei; Seymour, Ben; Hosomi, Koichi; Kishima, Haruhiko; Shimizu, Takeshi; Yokoi, Hiroshi; Hirata, Masayuki; Yoshimine, Toshiki; Kamitani, Yukiyasu; Saitoh, Youichi

2016-01-01

The cause of pain in a phantom limb after partial or complete deafferentation is an important problem. A popular but increasingly controversial theory is that it results from maladaptive reorganization of the sensorimotor cortex, suggesting that experimental induction of further reorganization should affect the pain, especially if it results in functional restoration. Here we use a brain–machine interface (BMI) based on real-time magnetoencephalography signals to reconstruct affected hand movements with a robotic hand. BMI training induces significant plasticity in the sensorimotor cortex, manifested as improved discriminability of movement information and enhanced prosthetic control. Contrary to our expectation that functional restoration would reduce pain, the BMI training with the phantom hand intensifies the pain. In contrast, BMI training designed to dissociate the prosthetic and phantom hands actually reduces pain. These results reveal a functional relevance between sensorimotor cortical plasticity and pain, and may provide a novel treatment with BMI neurofeedback. PMID:27807349

Mediterranean marine biodiversity under threat: Reviewing influence of marine litter on species.

PubMed

Deudero, Salud; Alomar, Carme

2015-09-15

The Mediterranean Sea is one of the most polluted seas worldwide, especially with regard to plastics. The presence of this emerging man made contaminant in marine environments precludes large effects and interactions with species exposed to massive litter quantities. In this review, available data of floating and seafloor litter around Mediterranean sub-basins are reported. A review of scientific literature on the interaction of plastic with marine biota resulted in the identification of 134 species, several taxa and feeding strategies affected from 1986 to 2014. Data from 17,334 individuals showed different levels of ingestion and effects on catalogued IUCN species (marine mammals and sea turtles) in addition to several pelagic fish and elasmobranchs. Biodiversity is certainly under threat, and knowledge of the extent of taxa affected is of concern considering the increasing plastic loads in the Mediterranean Sea and worldwide. Copyright © 2015 Elsevier Ltd. All rights reserved.

The use of dextran post free tissue transfer.

PubMed

Ridha, H; Jallali, N; Butler, P E

2006-01-01

Dextran has been used in microsurgery to reduce the risk of free tissue transfer loss. A number of regimens which vary considerably in dosage and timing have been published in the literature. Using a postal questionnaire, a survey was conducted to delineate the current practise of UK plastic surgeons. Data were received from 161 plastic surgeons in 51 units (response rate of 61%). Forty-five percent of microsurgeons routinely use dextran post-operatively whilst 29% use alternative thromboprophylaxis. The indications, post-operative regimes and duration of administration of dextran vary significantly amongst surgeons and units. The reported success rates of free tissue transfer and digital replants were 97 and 85.1%, respectively, and was not significantly affected by the use of dextran. We conclude that there is considerable variation amongst UK plastic surgeons regarding thromboprophylaxis post microsurgery. Our data suggest that the use of dextrans does not affect free tissue transfer success rates.

[Physical activity: positive impact on brain plasticity].

PubMed

Achiron, Anat; Kalron, Alon

2008-03-01

The central nervous system has a unique capability of plasticity that enables a single neuron or a group of neurons to undergo functional and constructional changes that are important to learning processes and for compensation of brain damage. The current review aims to summarize recent data related to the effects of physical activity on brain plasticity. In the last decade it was reported that physical activity can affect and manipulate neuronal connections, synaptic activity and adaptation to new neuronal environment following brain injury. One of the most significant neurotrophic factors that is critical for synaptic re-organization and is influenced by physical activity is brain-derived neurotrophic factor (BDNF). The frequency of physical activity and the intensity of exercises are of importance to brain remodeling, support neuronal survival and positively affect rehabilitation therapy. Physical activity should be employed as a tool to improve neural function in healthy subjects and in patients suffering from neurological damage.

Learning to Perceive Structure from Motion and Neural Plasticity in Patients with Alzheimer's Disease

ERIC Educational Resources Information Center

Kim, Nam-Gyoon; Park, Jong-Hee

2010-01-01

Recent research has demonstrated that Alzheimer's disease (AD) affects the visual sensory pathways, producing a variety of visual deficits, including the capacity to perceive structure-from-motion (SFM). Because the sensory areas of the adult brain are known to retain a large degree of plasticity, the present study was conducted to explore whether…

Moisture Sorption in Artificially aged wood-plastic composites

Treesearch

B. Kristoffer Segerholm; Rebecca E. Ibach; Magnus E.P. Wålinder

2012-01-01

Moisture sorption in wood-plastic composites (WPCs) affects their durability and dimensional stability. In certain outdoor exposures, the moisture properties of WPCs are altered due to e.g. cracks induced by swelling and shrinkage of the components, as well as UV degradation or biological attack. The aim of this work was to study the effect of different artificial...

Energy dynamics in stressed magnetic fields - The filamentation and flare instabilities

NASA Technical Reports Server (NTRS)

Van Hoven, G.; Steinolfson, R. S.; Tachi, T.

1983-01-01

The thermal and tearing instabilities are believed to be the two primary temperature modification mechanisms in sheared astrophysical magnetic fields. The former gives rise to the formation of cool filaments and the latter to the release of magnetic energy. It has long been known that these processes are interrelated, most conspicuously in the case of the solar corona where prominences often precede flares within the same magnetic structure. It is also clear, from first principles, that the energy transport underlying the thermal instability should have a strong effect on the resistivity which facilitates magnetic tearing, and that the energy release of the latter should affect the temperature drop of the former. This paper describes some results of the first calculations which attempt to unify the dynamic treatment of these two coexisting instabilities. Growth rates as a function of resistivity, and examples of the primary mode structures are provided, along with a discussion of some critical aspects of the interaction of these two astrophysical energy flux mechanisms.

Coherent Beam-Beam Instability in Collisions with a Large Crossing Angle

NASA Astrophysics Data System (ADS)

Ohmi, K.; Kuroo, N.; Oide, K.; Zhou, D.; Zimmermann, F.

2017-09-01

In recent years the "crab-waist collision" scheme [P. Raimondi, Proceedings of 2nd SuperB Workshop, Frascati, 2006.; M. Zobov et al., Phys. Rev. Lett. 104, 174801 (2010), 10.1103/PhysRevLett.104.174801] has become popular for circular e+ e- colliders. The designs of several future colliders are based on this scheme. So far the beam-beam effects for collisions under a large crossing angle with or without crab waist were mostly studied using weak-strong simulations. We present here strong-strong simulations showing a novel strong coherent head-tail instability, which can limit the performance of proposed future colliders. We explain the underlying instability mechanism starting from the "cross-wake force" induced by the beam-beam interaction. Using this beam-beam wake, the beam-beam head tail modes are studied by an eigenmode analysis. The instability may affect all collider designs based on the crab-waist scheme. We suggest an experimental verification at SuperKEKB during its commissioning phase II.

Analytical studies on the instabilities of heterogeneous intelligent traffic flow

NASA Astrophysics Data System (ADS)

Ngoduy, D.

2013-10-01

It has been widely reported in literature that a small perturbation in traffic flow such as a sudden deceleration of a vehicle could lead to the formation of traffic jams without a clear bottleneck. These traffic jams are usually related to instabilities in traffic flow. The applications of intelligent traffic systems are a potential solution to reduce the amplitude or to eliminate the formation of such traffic instabilities. A lot of research has been conducted to theoretically study the effect of intelligent vehicles, for example adaptive cruise control vehicles, using either computer simulation or analytical method. However, most current analytical research has only applied to single class traffic flow. To this end, the main topic of this paper is to perform a linear stability analysis to find the stability threshold of heterogeneous traffic flow using microscopic models, particularly the effect of intelligent vehicles on heterogeneous (or multi-class) traffic flow instabilities. The analytical results will show how intelligent vehicle percentages affect the stability of multi-class traffic flow.

The association between housing instability, food insecurity, and diabetes self-efficacy in low-income adults.

PubMed

Vijayaraghavan, Maya; Jacobs, Elizabeth A; Seligman, Hilary; Fernandez, Alicia

2011-11-01

Limited data exist on whether structural factors associated with poverty such as inadequate housing and food insecurity affect diabetes care. In a sample of low-income participants with diabetes (N=711), we sought to determine if housing instability was associated with lower diabetes self-efficacy, and whether this relationship was mediated by food insecurity. We ordered housing from most to least stable. We observed a linear decrease in diabetes self-efficacy as housing instability increased (p<.01). After adjusting for age, sex, race/ethnicity, and alcohol or substance use, adults lacking a usual place to stay had lower self-efficacy than those who owned their own home (ß-coefficient -0.94, 95% CI -1.88, -0.01). Food insecurity mediated the association between housing instability and diabetes self-efficacy (ß-coefficient -0.64, 95% CI -1.57, 0.31). Our findings suggest that inadequate access to food lowers self-efficacy among adults with diabetes, and supports provision of food to unstably housed adults as part of diabetes care.

A dielectric elastomer actuator coupled with water: snap-through instability and giant deformation

NASA Astrophysics Data System (ADS)

Godaba, Hareesh; Foo, Choon Chiang; Zhang, Zhi Qian; Khoo, Boo Cheong; Zhu, Jian

2015-04-01

A dielectric elastomer actuator is one class of soft actuators which can deform in response to voltage. Dielectric elastomer actuators coupled with liquid have recently been developed as soft pumps, soft lenses, Braille displays, etc. In this paper, we conduct experiments to investigate the performance of a dielectric elastomer actuator which is coupled with water. The membrane is subject to a constant water pressure, which is found to significantly affect the electromechanical behaviour of the membrane. When the pressure is small, the membrane suffers electrical breakdown before snap-through instability, and achieves a small voltage-induced deformation. When the pressure is higher to make the membrane near the verge of the instability, the membrane can achieve a giant voltage-induced deformation, with an area strain of 1165%. When the pressure is large, the membrane suffers pressure-induced snap-through instability and may collapse due to a large amount of liquid enclosed by the membrane. Theoretical analyses are conducted to interpret these experimental observations.

Rural plastic emissions into the largest mountain lake of the Eastern Carpathians.

PubMed

Mihai, Florin-Constantin

2018-05-01

The lack of proper waste collection systems leads to plastic pollution in rivers in proximity to rural communities. This environmental threat is more widespread among mountain communities which are prone to frequent flash floods during the warm season. This paper estimates the amounts of plastic bottles dumped into the Izvoru Muntelui lake by upstream rural communities. The plastic pollution dimension between seasonal floods which affected the Bistrita catchment area during 2005-2012 is examined. The floods dumped over 290 tonnes of plastic bottles into the lake. Various scenarios are tested in order to explain each amount of plastic waste collected by local authorities during sanitation activities. The results show that rural municipalities are responsible for 85.51% of total plastic bottles collected during 2005-2010. The source of plastic pollution is mainly local. The major floods of July 2008 and June 2010 collected most of the plastic bottles scattered across the Bistrita river catchment (56 villages) and dumped them into the lake. These comparisons validate the proposed method as a reliable tool in the assessment process of river plastic pollution, which may also be applied in other geographical areas. Tourism and leisure activities are also found to be responsible for plastic pollution in the study area. A new regional integrated waste management system should improve the waste collection services across rural municipalities at the county level when it is fully operational. This paper demonstrates that rural communities are significant contributors of plastics into water bodies.

Rural plastic emissions into the largest mountain lake of the Eastern Carpathians

PubMed Central

2018-01-01

The lack of proper waste collection systems leads to plastic pollution in rivers in proximity to rural communities. This environmental threat is more widespread among mountain communities which are prone to frequent flash floods during the warm season. This paper estimates the amounts of plastic bottles dumped into the Izvoru Muntelui lake by upstream rural communities. The plastic pollution dimension between seasonal floods which affected the Bistrita catchment area during 2005–2012 is examined. The floods dumped over 290 tonnes of plastic bottles into the lake. Various scenarios are tested in order to explain each amount of plastic waste collected by local authorities during sanitation activities. The results show that rural municipalities are responsible for 85.51% of total plastic bottles collected during 2005–2010. The source of plastic pollution is mainly local. The major floods of July 2008 and June 2010 collected most of the plastic bottles scattered across the Bistrita river catchment (56 villages) and dumped them into the lake. These comparisons validate the proposed method as a reliable tool in the assessment process of river plastic pollution, which may also be applied in other geographical areas. Tourism and leisure activities are also found to be responsible for plastic pollution in the study area. A new regional integrated waste management system should improve the waste collection services across rural municipalities at the county level when it is fully operational. This paper demonstrates that rural communities are significant contributors of plastics into water bodies. PMID:29892426

Positional stability of field-reversed-configurations in the presence of resistive walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rath, N., E-mail: nrath@trialphanenergy.com; Onofri, M.; Barnes, D. C.

2016-06-15

We show that in a field-reversed-configuration, the plasma is unstable to either transverse or axial rigid displacement, but never to both. Driving forces are found to be parallel to the direction of displacement with no orthogonal components. Furthermore, we demonstrate that the properties of a resistive wall (geometry and resistivity) in the vicinity of the plasma do not affect whether the plasma is stable or unstable, but in the case of an unstable system determine the instability growth rate. Depending on the properties of the wall, the instability growth is dominated by plasma inertia (and not affected by wall resistivity)more » or dominated by ohmic dissipation of wall eddy currents (and thus proportional to the wall resistivity).« less

Effects of planar shear on the three-dimensional instability in flow past a circular cylinder

NASA Astrophysics Data System (ADS)

Park, Doohyun; Yang, Kyung-Soo

2018-03-01

A Floquet stability analysis has been carried out in order to investigate how a planar shear in wake flow affects the three-dimensional (3D) instability in the near-wake region. We consider a circular cylinder immersed in a freestream with planar shear. The cylinder was implemented in a Cartesian grid system by means of an immersed boundary method. Planar shear tends to promote the primary instability, known as Hopf bifurcation where steady flow bifurcates into time-periodic flow, in the sense that its critical Reynolds number decreases with increasing planar shear. The effects of planar shear on the 3D instability are different depending on the type of 3D instability. The flow asymmetry caused by the planar shear suppresses a QP-type mode but generates a C-type mode. The conventional A and B modes are stabilized by the planar shear, whereas mode C is intensified with increasing shear. The criticality of each 3D mode is discussed, and the neutral stability curves for each 3D mode are presented. The current Floquet results have been validated by using direct numerical simulation for some selected cases of flow parameters.

From waste plastics to industrial raw materials: A life cycle assessment of mechanical plastic recycling practice based on a real-world case study.

PubMed

Gu, Fu; Guo, Jianfeng; Zhang, Wujie; Summers, Peter A; Hall, Philip

2017-12-01

Mechanical recycling of waste plastics is an environmental solution to the problem of waste plastic disposal, and has already become a common practice in industry. However, limited information can be found on either the industralised plastic recycling or the recycled materials, despite the use of recycled plastics has already extended to automobile production. This study investigates the life cycle environmental impacts of mechanical plastic recycling practice of a plastic recycling company in China. Waste plastics from various sources, such as agricultural wastes, plastic product manufacturers, collected solid plastic wastes and parts dismantled from waste electric and electronic equipments, are processed in three routes with products end up in different markets. The results of life cycle assessments show that the extrusion process has the largest environmental impacts, followed by the use of fillers and additives. Compared to production of virgin plastics and composites, the mechanical recycling is proved to be a superior alternative in most environmental aspects. Substituting virgin plastic composites with recycled plastic composites has achieved the highest environmental benefits, as virgin composite production has an impact almost 4 times higher that of the recycled composite production in each ReCiPe endpoint damage factor. Sensitivity analysis shows that the coverage of collecting network contribute affect little to overall environmental impact, and centralisation plays an important role in reducing overall environmental impacts. Among the fillers and additives, impact modifiers account for the most significant contributions to the environmental impacts of recycled composites. This study provides necessary information about the existing industrialised plastic recycling practice, and recommendations are given. Research implications are presented with the purpose to achieve higher substitution rate and lower environmental impact. Copyright © 2017 Elsevier B.V. All rights reserved.

Impacts of macro - and microplastic on macrozoobenthos abundance in intertidal zone

NASA Astrophysics Data System (ADS)

Bangun, A. P.; Wahyuningsih, H.; Muhtadi, A.

2018-02-01

Plastics pollution in coastal areas is one of the topics that have received more attention over the past few years. The intertidal zone is a waters area that is directly affected by contamination of plastic waste from land and sea. The purpose of this study was to analyze the types and abundance of plastic waste in the intertidal zone and its impact on macrozoobenthos abundance. This research was conducted at Pesisir Desa Jaring Halus in February-April 2017. Macrozoobenthos and macro - micro plastic were collected by using quadratic transect. Sediments were collected with a core, to a depth of 30 cm. Microplastic and macroplastic abundances were analyzed using separation of sediment density and hand sorting. The dominant micro plastic types were film (52.30%), fiber (24.88%), fragments (22.74%), followed by pellets (0.1%). The total number of microplastics were 326,33 items and macro plastic were 308 items. Macroplastic abundance is positively correlated with microplastic (0.765). The abundance of macrozoobenthos is negatively correlated with microplastic abundance (-0.368) and with macro plastic abundance (-0.633). The management strategies were suggested clean up marine debris, decrease plastic using and built up the station of debris processing.

Disparities in Aesthetic Procedures Performed by Plastic Surgery Residents.

PubMed

Silvestre, Jason; Serletti, Joseph M; Chang, Benjamin

2017-05-01

Operative experience in aesthetic surgery is an important issue affecting plastic surgery residents. This study addresses the variability of aesthetic surgery experience during plastic surgery residency. National operative case logs of chief residents in independent/combined and integrated plastic surgery residency programs were analyzed (2011-2015). Fold differences between the bottom and top 10th percentiles of residents were calculated for each aesthetic procedure category and training model. The number of residents not achieving case minimums was also calculated. Case logs of 818 plastic surgery residents were analyzed. There was marked variability in craniofacial (range, 6.0-15.0), breast (range, 2.4-5.9), trunk/extremity (range, 3.0-16.0), and miscellaneous (range, 2.7-22.0) procedure categories. In 2015, the bottom 10th percentile of integrated and independent/combined residents did not achieve case minimums for botulinum toxin and dermal fillers. Case minimums were achieved for the other aesthetic procedure categories for all graduating years. Significant variability persists for many aesthetic procedure categories during plastic surgery residency training. Greater efforts may be needed to improve the aesthetic surgery experience of plastic surgery residents. © 2016 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com

Phenotypic plasticity in sex pheromone production in Bicyclus anynana butterflies

PubMed Central

Dion, Emilie; Monteiro, Antónia; Yew, Joanne Y.

2016-01-01

Phenotypic plasticity refers to the environmental control of phenotypes. Cues experienced during development (developmental plasticity) or during adulthood (acclimatization) can both affect adult phenotypes. Phenotypic plasticity has been described in many traits but examples of developmental plasticity in physiological traits, in particular, remain scarce. We examined developmental plasticity and acclimatization in pheromone production in the butterfly Bicyclus anynana in response to rearing temperature. B. anynana lives in the African tropics where warm rearing temperatures of the wet season produce active males that court and females that choose, whereas cooler temperatures of the dry season lead to choosy less active males and courting females. We hypothesized that if male pheromone production is costly, it should be reduced in the dry season form. After describing the ultrastructure of pheromone producing cells, we showed that dry season males produced significantly less sex pheromones than wet season males, partly due to acclimatization and partly due to developmental plasticity. Variation in levels of one of the compounds is associated with differential regulation of a pheromone biosynthetic enzyme gene. This plasticity might be an adaptation to minimize pheromone production costs during the stressful dry season. PMID:27966579

Performance of High-Convergence, Layered DT Implosions on Power-Scaling Experiments at National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smalyuk, V. A.; Atherton, L. J.; Benedetti, L. R.

The radiation-driven, low-adiabat, cryogenic DT layered plastic capsule implosions were carried out on the National Ignition Facility (NIF) to study the sensitivity of performance to peak power and drive duration. An implosion with extended drive and at reduced peak power of 350 TW achieved the highest compression with fuel areal density of ~1.3±0.1 g/cm 2, representing a significant step from previously measured ~1.0 g/cm 2 toward a goal of 1.5 g/cm 2. Moreover, for future experiments will focus on understanding and mitigating hydrodynamic instabilities and mix, and improving symmetry required to reach the threshold for thermonuclear ignition on NIF.

Performance of High-Convergence, Layered DT Implosions on Power-Scaling Experiments at National Ignition Facility

DOE PAGES

Smalyuk, V. A.; Atherton, L. J.; Benedetti, L. R.; ...

2013-10-19

The radiation-driven, low-adiabat, cryogenic DT layered plastic capsule implosions were carried out on the National Ignition Facility (NIF) to study the sensitivity of performance to peak power and drive duration. An implosion with extended drive and at reduced peak power of 350 TW achieved the highest compression with fuel areal density of ~1.3±0.1 g/cm 2, representing a significant step from previously measured ~1.0 g/cm 2 toward a goal of 1.5 g/cm 2. Moreover, for future experiments will focus on understanding and mitigating hydrodynamic instabilities and mix, and improving symmetry required to reach the threshold for thermonuclear ignition on NIF.

Feeding ecology and ingestion of plastic fragments by Priacanthus arenatus: What's the fisheries contribution to the problem?

PubMed

Cardozo, Ana L P; Farias, Eduardo G G; Rodrigues-Filho, Jorge L; Moteiro, Isabel B; Scandolo, Tatianny M; Dantas, David V

2018-05-01

Atlantic Bigeye (Priacanthus arenatus) is a demersal species from the Priacanthidae family with little literature relating to its biology and catch aspects. Due to this lack of research, the focus of this effort was to describe the feeding preferences of Atlantic Bigeye and to evaluate the influence of plastic debris derived from the local fisheries activities on its diet. The most important items were Corophiidae, Penaeidae, Actinopterygii, Isopoda, Cephalopoda, Policheta and plastic. Plastic was present in 49.17% of the stomachs analyzed. A total of 210 plastic fragments were found, and 63% were derived from fishing. Of those, 55% were derived from paint fragments from vessels and 8% from synthetic fibers (PA). The results suggest that plastic fragments found in stomachs are related to the species' natural diet and that this debris is locally deposited in the coastal environment. Fishing resources appear to have been affected by this local marine pollution. Copyright © 2018 Elsevier Ltd. All rights reserved.

The use of potassium hydroxide (KOH) solution as a suitable approach to isolate plastics ingested by marine organisms.

PubMed

Kühn, Susanne; van Werven, Bernike; van Oyen, Albert; Meijboom, André; Bravo Rebolledo, Elisa L; van Franeker, Jan A

2017-02-15

In studies of plastic ingestion by marine wildlife, visual separation of plastic particles from gastrointestinal tracts or their dietary content can be challenging. Earlier studies have used solutions to dissolve organic materials leaving synthetic particles unaffected. However, insufficient tests have been conducted to ensure that different categories of consumer products partly degraded in the environment and/or in gastrointestinal tracts were not affected. In this study 63 synthetic materials and 11 other dietary items and non-plastic marine debris were tested. Irrespective of shape or preceding environmental history, most polymers resisted potassium hydroxide (KOH) solution, with the exceptions of cellulose acetate from cigarette filters, some biodegradable plastics and a single polyethylene sheet. Exposure of hard diet components and other marine debris showed variable results. In conclusion, the results confirm that usage of KOH solutions can be a useful approach in general quantitative studies of plastic ingestion by marine wildlife. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

A review on thermal and catalytic pyrolysis of plastic solid waste (PSW).

PubMed

Al-Salem, S M; Antelava, A; Constantinou, A; Manos, G; Dutta, A

2017-07-15

Plastic plays an important role in our daily lives due to its versatility, light weight and low production cost. Plastics became essential in many sectors such as construction, medical, engineering applications, automotive, aerospace, etc. In addition, economic growth and development also increased our demand and dependency on plastics which leads to its accumulation in landfills imposing risk on human health, animals and cause environmental pollution problems such as ground water contamination, sanitary related issues, etc. Hence, a sustainable and an efficient plastic waste treatment is essential to avoid such issues. Pyrolysis is a thermo-chemical plastic waste treatment technique which can solve such pollution problems, as well as, recover valuable energy and products such as oil and gas. Pyrolysis of plastic solid waste (PSW) has gained importance due to having better advantages towards environmental pollution and reduction of carbon footprint of plastic products by minimizing the emissions of carbon monoxide and carbon dioxide compared to combustion and gasification. This paper presents the existing techniques of pyrolysis, the parameters which affect the products yield and selectivity and identify major research gaps in this technology. The influence of different catalysts on the process as well as review and comparative assessment of pyrolysis with other thermal and catalytic plastic treatment methods, is also presented. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dosage-dependent non-linear effect of L-dopa on human motor cortex plasticity.

PubMed

Monte-Silva, Katia; Liebetanz, David; Grundey, Jessica; Paulus, Walter; Nitsche, Michael A

2010-09-15

The neuromodulator dopamine affects learning and memory formation and their likely physiological correlates, long-term depression and potentiation, in animals and humans. It is known from animal experiments that dopamine exerts a dosage-dependent, inverted U-shaped effect on these functions. However, this has not been explored in humans so far. In order to reveal a non-linear dose-dependent effect of dopamine on cortical plasticity in humans, we explored the impact of 25, 100 and 200 mg of L-dopa on transcranial direct current (tDCS)-induced plasticity in twelve healthy human subjects. The primary motor cortex served as a model system, and plasticity was monitored by motor evoked potential amplitudes elicited by transcranial magnetic stimulation. As compared to placebo medication, low and high dosages of L-dopa abolished facilitatory as well as inhibitory plasticity, whereas the medium dosage prolonged inhibitory plasticity, and turned facilitatory plasticity into inhibition. Thus the results show clear non-linear, dosage-dependent effects of dopamine on both facilitatory and inhibitory plasticity, and support the assumption of the importance of a specific dosage of dopamine optimally suited to improve plasticity. This might be important for the therapeutic application of dopaminergic agents, especially for rehabilitative purposes, and explain some opposing results in former studies.

Fast Transverse Beam Instability Caused by Electron Cloud Trapped in Combined Function Magnets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antipov, Sergey

Electron cloud instabilities affect the performance of many circular high-intensity particle accelerators. They usually have a fast growth rate and might lead to an increase of the transverse emittance and beam loss. A peculiar example of such an instability is observed in the Fermilab Recycler proton storage ring. Although this instability might pose a challenge for future intensity upgrades, its nature had not been completely understood. The phenomena has been studied experimentally by comparing the dynamics of stable and unstable beam, numerically by simulating the build-up of the electron cloud and its interaction with the beam, and analytically by constructing a model of an electron cloud driven instability with the electrons trapped in combined function dipoles. Stabilization of the beam by a clearing bunch reveals that the instability is caused by the electron cloud, trapped in beam optics magnets. Measurements of microwave propagation confirm the presence of the cloud in the combined function dipoles. Numerical simulations show that up to 10more » $$^{-2}$$ of the particles can be trapped by their magnetic field. Since the process of electron cloud build-up is exponential, once trapped this amount of electrons significantly increases the density of the cloud on the next revolution. In a combined function dipole this multi-turn accumulation allows the electron cloud reaching final intensities orders of magnitude greater than in a pure dipole. The estimated fast instability growth rate of about 30 revolutions and low mode frequency of 0.4 MHz are consistent with experimental observations and agree with the simulations. The created instability model allows investigating the beam stability for the future intensity upgrades.« less

Conditions for l =1 Pomeranchuk instability in a Fermi liquid

NASA Astrophysics Data System (ADS)

Wu, Yi-Ming; Klein, Avraham; Chubukov, Andrey V.

2018-04-01

We perform a microscopic analysis of how the constraints imposed by conservation laws affect q =0 Pomeranchuk instabilities in a Fermi liquid. The conventional view is that these instabilities are determined by the static interaction between low-energy quasiparticles near the Fermi surface, in the limit of vanishing momentum transfer q . The condition for a Pomeranchuk instability is set by Flc (s )=-1 , where Flc (s ) (a Landau parameter) is a properly normalized partial component of the antisymmetrized static interaction F (k ,k +q ;p ,p -q ) in a charge (c) or spin (s) subchannel with angular momentum l . However, it is known that conservation laws for total spin and charge prevent Pomeranchuk instabilities for l =1 spin- and charge-current order parameters. Our study aims to understand whether this holds only for these special forms of l =1 order parameters or is a more generic result. To this end we perform a diagrammatic analysis of spin and charge susceptibilities for charge and spin density order parameters, as well as perturbative calculations to second order in the Hubbard U . We argue that for l =1 spin-current and charge-current order parameters, certain vertex functions, which are determined by high-energy fermions, vanish at Fl=1 c (s )=-1 , preventing a Pomeranchuk instability from taking place. For an order parameter with a generic l =1 form factor, the vertex function is not expressed in terms of Fl=1 c (s ), and a Pomeranchuk instability may occur when F1c (s )=-1 . We argue that for other values of l , a Pomeranchuk instability may occur at Flc (s )=-1 for an order parameter with any form factor.

Using sieving and pretreatment to separate plastics during end-of-life vehicle recycling.

PubMed

Stagner, Jacqueline A; Sagan, Barsha; Tam, Edwin Kl

2013-09-01

Plastics continue to be a challenge for recovering materials at the end-of-life for vehicles. However, it may be possible to improve the recovery of plastics by exploiting material characteristics, such as shape, or by altering their behavior, such as through temperature changes, in relation to recovery processes and handling. Samples of a 2009 Dodge Challenger front fascia were shredded in a laboratory-scale hammer mill shredder. A 2 × 2 factorial design study was performed to determine the effect of sample shape (flat versus curved) and sample temperature (room temperature versus cryogenic temperature) on the size of the particles exiting from the shredder. It was determined that sample shape does not affect the particle size; however, sample temperature does affect the particle size. At cryogenic temperatures, the distribution of particle sizes is much narrower than at room temperature. Having a more uniform particle size could make recovery of plastic particles, such as these more efficient during the recycling of end-of-life vehicles. Samples of Chrysler minivan headlights were also shredded at room temperature and at cryogenic temperatures. The size of the particles of the two different plastics in the headlights is statistically different both at room temperature and at cryogenic temperature, and the particles are distributed narrowly. The research suggests that incremental changes in end-of-life vehicle processing could be effective in aiding materials recovery.

The intra-day dynamics of affect, self-esteem, tiredness, and suicidality in Major Depression.

PubMed

Crowe, Eimear; Daly, Michael; Delaney, Liam; Carroll, Susan; Malone, Kevin M

2018-02-21

Despite growing interest in the temporal dynamics of Major Depressive Disorder (MDD), we know little about the intra-day fluctuations of key symptom constructs. In a study of momentary experience, the Experience Sampling Method captured the within-day dynamics of negative affect, positive affect, self-esteem, passive suicidality, and tiredness across clinical MDD (N= 31) and healthy control groups (N= 33). Ten symptom measures were taken per day over 6 days (N= 2231 observations). Daily dynamics were modeled via intra-day time-trends, variability, and instability in symptoms. MDD participants showed significantly increased variability and instability in negative affect, positive affect, self-esteem, and suicidality. Significantly different time-trends were found in positive affect (increased diurnal variation and an inverted U-shaped pattern in MDD, compared to a positive linear trend in controls) and tiredness (decreased diurnal variation in MDD). In the MDD group only, passive suicidality displayed a negative linear trend and self-esteem displayed a quadratic inverted U trend. MDD and control participants thus showed distinct dynamic profiles in all symptoms measured. As well as the overall severity of symptoms, intra-day dynamics appear to define the experience of MDD symptoms. Copyright © 2018 Elsevier B.V. All rights reserved.

Experimental investigation of sound generation by a protuberance in a laminar boundary layer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kobayashi, M.; Asai, M.; Inasawa, A.

2014-08-15

Sound radiation from a two-dimensional protuberance glued on the wall in a laminar boundary layer was investigated experimentally at low Mach numbers. When the protuberance was as high as the boundary-layer thickness, a feedback-loop mechanism set in between protuberance-generated sound and Tollmien-Schlichting (T-S) waves generated by the leading-edge receptivity to the upstream-propagating sound. Although occurrence of a separation bubble immediately upstream of the protuberance played important roles in the evolution of instability waves into vortices interacting with the protuberance, the frequency of tonal vortex sound was determined by the selective amplification of T-S waves in the linear instability stage upstreammore » of the separation bubble and was not affected by the instability of the separation bubble.« less

Patterns, Instabilities, Colors, and Flows in Vertical Foam Films

NASA Astrophysics Data System (ADS)

Yilixiati, Subinuer; Wojcik, Ewelina; Zhang, Yiran; Pearsall, Collin; Sharma, Vivek

2015-03-01

Foams find use in many applications in daily life, industry and biology. Examples include beverages, firefighting foam, cosmetics, foams for oil recovery and foams formed by pollutants. Foams are collection of bubbles separated by thin liquid films that are stabilized against drainage by the presence of surfactant molecules. Drainage kinetics and stability of the foam are strongly influenced by surfactant type, addition of particles, proteins and polymers. In this study, we utilize the thin film interference colors as markers for identifying patterns, instabilities and flows within vertical foam films. We experimentally study the emergence of thickness fluctuations near the borders and within thinning films, and study how buoyancy, capillarity and gravity driven instabilities and flows, are affected by variation in bulk and interfacial physicochemical properties dependent on the choice of constituents.

Metastable and unstable cellular solidification of colloidal suspensions

NASA Astrophysics Data System (ADS)

Deville, Sylvain; Maire, Eric; Bernard-Granger, Guillaume; Lasalle, Audrey; Bogner, Agnès; Gauthier, Catherine; Leloup, Jérôme; Guizard, Christian

2009-12-01

Colloidal particles are often seen as big atoms that can be directly observed in real space. They are therefore becoming increasingly important as model systems to study processes of interest in condensed-matter physics such as melting, freezing and glass transitions. The solidification of colloidal suspensions has long been a puzzling phenomenon with many unexplained features. Here, we demonstrate and rationalize the existence of instability and metastability domains in cellular solidification of colloidal suspensions, by direct in situ high-resolution X-ray radiography and tomography observations. We explain such interface instabilities by a partial Brownian diffusion of the particles leading to constitutional supercooling situations. Processing under unstable conditions leads to localized and global kinetic instabilities of the solid/liquid interface, affecting the crystal morphology and particle redistribution behaviour.

Development of interface-dominant bulk Cu/V nanolamellar composites by cross accumulative roll bonding

PubMed Central

Zeng, L. F.; Gao, R.; Xie, Z. M.; Miao, S.; Fang, Q. F.; Wang, X. P.; Zhang, T.; Liu, C. S.

2017-01-01

Traditional nanostructured metals are inherently comprised of a high density of high-energy interfaces that make this class of materials not stable in extreme conditions. Therefore, high performance bulk nanostructured metals containing stable interfaces are highly desirable for extreme environments applications. Here, we reported an attractive bulk Cu/V nanolamellar composite that was successfully developed by integrating interface engineering and severe plastic deformation techniques. The layered morphology and ordered Cu/V interfaces remained stable with respect to continued rolling (total strain exceeding 12). Most importantly, for layer thickness of 25 nm, this bulk Cu/V nanocomposite simultaneously achieves high strength (hardness of 3.68 GPa) and outstanding thermal stability (up to 700 °C), which are quite difficult to realize simultaneously in traditional nanostructured materials. Such extraordinary property in our Cu/V nanocomposite is achieved via an extreme rolling process that creates extremely high density of stable Cu/V heterophase interfaces and low density of unstable grain boundaries. In addition, high temperature annealing result illustrates that Rayleigh instability is the dominant mechanism driving the onset of thermal instability after exposure to 800 °C. PMID:28094346

Benefits of Moderate-Z Ablators for Direct-Drive Inertial Confinement Fusion

NASA Astrophysics Data System (ADS)

Lafon, M.; Betti, R.; Anderson, K. S.; Collins, T. J. B.; Skupsky, S.; McKenty, P. W.

2014-10-01

Control of hydrodynamic instabilities and DT-fuel preheating by hot electrons produced by laser-plasma interaction is crucial in inertial confinement fusion. Moderate- Z ablators have been shown to reduce the laser imprinting on target and suppress the generation of hot electrons from the two-plasmon-decay instability. These results have motivated the use of ablators of higher- Z than pure plastic in direct-drive-ignition target designs for the National Ignition Facility (NIF). Two-dimensional radiation-hydrodynamic simulations assess the robustness of these ignition designs to laser imprint and capsule nonuniformities. The complex behavior of the hydrodynamic stability of mid- Z ablators is investigated through single and multimode simulations. A polar-drive configuration is developed within the NIF Laser System specifications for each ablator material. The use of multilayer ablators is also investigated to enhance the hydrodynamic stability. Results indicate that ignition target designs using mid- Z ablators exhibit good hydrodynamic properties, leading to high target gain for direct-drive implosions on the NIF. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944 and the Office of Fusion Energy Sciences Number DE-FG02-04ER54786.

Effects of temperature, loading rate and nanowire length on torsional deformation and mechanical properties of aluminium nanowires investigated using molecular dynamics simulation

NASA Astrophysics Data System (ADS)

Sung, Po-Hsien; Wu, Cheng-Da; Fang, Te-Hua

2012-05-01

Single-crystal aluminium nanowires under torsion are studied using molecular dynamics simulations based on the many-body tight-binding potential. The effects of temperature, loading rate and nanowire length are evaluated in terms of atomic trajectories, potential energy, von Mises stress, a centrosymmetry parameter, torque, shear modulus and radial distribution function. Simulation results clearly show that torsional deformation begins at the surface, extends close to the two ends and finally diffuses to the middle part. The critical torsional angle which represents the beginning of plastic deformation varies with different conditions. Before the critical torsional angle is reached, the potential energy and the torque required for the deformation of a nanowire significantly increase with the torsional angle. The critical torsional angle increases with increasing nanowire length and loading rate and decreasing temperature. The torque required for the deformation decreases and the shear modulus increases with increasing nanowire length. For higher temperatures and higher loading rates, torsional buckling more easily occurs at the two ends of a nanowire, whereas it occurs towards the middle part at or below room temperature with lower loading rates. Geometry instability occurs before material instability (buckling) for a long nanowire.

Finite Atwood Number Effects on Deceleration-Phase Instability in Room-Temperature Direct-Drive Implosions

NASA Astrophysics Data System (ADS)

Miller, S.; Knauer, J. P.; Radha, P. B.; Goncharov, V. N.

2017-10-01

Performance degradation in direct-drive inertial confinement fusion implosions can be caused by several effects, one of which is Rayleigh-Taylor (RT) instability growth during the deceleration phase. In room-temperature plastic target implosions, this deceleration-phase RT growth is enhanced by the density discontinuity and finite Atwood numbers at the fuel-pusher interface. For the first time, an experimental campaign at the Omega Laser Facility systematically varied the ratio of deuterium-to-tritium (D-to-T) within the DT gas fill to change the Atwood number. The goal of the experiment was to understand the effects of Atwood number variation on observables like apparent ion temperature, yield, and variations in areal density and bulk fluid motion, which lead to broadening of neutron spectra along different lines of sight. Simulations by the hydrodynamic codes LILAC and DRACO were used to study growth rates for different D-to-T ratios and identify observable quantities effected by Atwood number variation. Results from simulations and the experiment are presented. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

The importance of Thermo-Hydro-Mechanical couplings and microstructure to strain localization in 3D continua with application to seismic faults. Part I: Theory and linear stability analysis

NASA Astrophysics Data System (ADS)

Rattez, Hadrien; Stefanou, Ioannis; Sulem, Jean

2018-06-01

A Thermo-Hydro-Mechanical (THM) model for Cosserat continua is developed to explore the influence of frictional heating and thermal pore fluid pressurization on the strain localization phenomenon. A general framework is presented to conduct a bifurcation analysis for elasto-plastic Cosserat continua with THM couplings and predict the onset of instability. The presence of internal lengths in Cosserat continua enables to estimate the thickness of the localization zone. This is done by performing a linear stability analysis of the system and looking for the selected wavelength corresponding to the instability mode with fastest finite growth coefficient. These concepts are applied to the study of fault zones under fast shearing. For doing so, we consider a model of a sheared saturated infinite granular layer. The influence of THM couplings on the bifurcation state and the shear band width is investigated. Taking representative parameters for a centroidal fault gouge, the evolution of the thickness of the localized zone under continuous shear is studied. Furthermore, the effect of grain crushing inside the shear band is explored by varying the internal length of the constitutive law.

Inertioelastic Flow Instability at a Stagnation Point

NASA Astrophysics Data System (ADS)

Burshtein, Noa; Zografos, Konstantinos; Shen, Amy Q.; Poole, Robert J.; Haward, Simon J.

2017-10-01

A number of important industrial applications exploit the ability of small quantities of high molecular weight polymer to suppress instabilities that arise in the equivalent flow of Newtonian fluids, a particular example being turbulent drag reduction. However, it can be extremely difficult to probe exactly how the polymer acts to, e.g., modify the streamwise near-wall eddies in a fully turbulent flow. Using a novel cross-slot flow configuration, we exploit a flow instability in order to create and study a single steady-state streamwise vortex. By quantitative experiment, we show how the addition of small quantities (parts per million) of a flexible polymer to a Newtonian solvent dramatically affects both the onset conditions for this instability and the subsequent growth of the axial vorticity. Complementary numerical simulations with a finitely extensible nonlinear elastic dumbbell model show that these modifications are due to the growth of polymeric stress within specific regions of the flow domain. Our data fill a significant gap in the literature between the previously reported purely inertial and purely elastic flow regimes and provide a link between the two by showing how the instability mode is transformed as the fluid elasticity is varied. Our results and novel methods are relevant to understanding the mechanisms underlying industrial uses of weakly elastic fluids and also to understanding inertioelastic instabilities in more confined flows through channels with intersections and stagnation points.

Structural plasticity of the social brain: Differential change after socio-affective and cognitive mental training.

PubMed

Valk, Sofie L; Bernhardt, Boris C; Trautwein, Fynn-Mathis; Böckler, Anne; Kanske, Philipp; Guizard, Nicolas; Collins, D Louis; Singer, Tania

2017-10-01

Although neuroscientific research has revealed experience-dependent brain changes across the life span in sensory, motor, and cognitive domains, plasticity relating to social capacities remains largely unknown. To investigate whether the targeted mental training of different cognitive and social skills can induce specific changes in brain morphology, we collected longitudinal magnetic resonance imaging (MRI) data throughout a 9-month mental training intervention from a large sample of adults between 20 and 55 years of age. By means of various daily mental exercises and weekly instructed group sessions, training protocols specifically addressed three functional domains: (i) mindfulness-based attention and interoception, (ii) socio-affective skills (compassion, dealing with difficult emotions, and prosocial motivation), and (iii) socio-cognitive skills (cognitive perspective-taking on self and others and metacognition). MRI-based cortical thickness analyses, contrasting the different training modules against each other, indicated spatially diverging changes in cortical morphology. Training of present-moment focused attention mostly led to increases in cortical thickness in prefrontal regions, socio-affective training induced plasticity in frontoinsular regions, and socio-cognitive training included change in inferior frontal and lateral temporal cortices. Module-specific structural brain changes correlated with training-induced behavioral improvements in the same individuals in domain-specific measures of attention, compassion, and cognitive perspective-taking, respectively, and overlapped with task-relevant functional networks. Our longitudinal findings indicate structural plasticity in well-known socio-affective and socio-cognitive brain networks in healthy adults based on targeted short daily mental practices. These findings could promote the development of evidence-based mental training interventions in clinical, educational, and corporate settings aimed at cultivating social intelligence, prosocial motivation, and cooperation.

Structural plasticity of the social brain: Differential change after socio-affective and cognitive mental training

PubMed Central

Valk, Sofie L.; Bernhardt, Boris C.; Trautwein, Fynn-Mathis; Böckler, Anne; Kanske, Philipp; Guizard, Nicolas; Collins, D. Louis; Singer, Tania

2017-01-01

Although neuroscientific research has revealed experience-dependent brain changes across the life span in sensory, motor, and cognitive domains, plasticity relating to social capacities remains largely unknown. To investigate whether the targeted mental training of different cognitive and social skills can induce specific changes in brain morphology, we collected longitudinal magnetic resonance imaging (MRI) data throughout a 9-month mental training intervention from a large sample of adults between 20 and 55 years of age. By means of various daily mental exercises and weekly instructed group sessions, training protocols specifically addressed three functional domains: (i) mindfulness-based attention and interoception, (ii) socio-affective skills (compassion, dealing with difficult emotions, and prosocial motivation), and (iii) socio-cognitive skills (cognitive perspective-taking on self and others and metacognition). MRI-based cortical thickness analyses, contrasting the different training modules against each other, indicated spatially diverging changes in cortical morphology. Training of present-moment focused attention mostly led to increases in cortical thickness in prefrontal regions, socio-affective training induced plasticity in frontoinsular regions, and socio-cognitive training included change in inferior frontal and lateral temporal cortices. Module-specific structural brain changes correlated with training-induced behavioral improvements in the same individuals in domain-specific measures of attention, compassion, and cognitive perspective-taking, respectively, and overlapped with task-relevant functional networks. Our longitudinal findings indicate structural plasticity in well-known socio-affective and socio-cognitive brain networks in healthy adults based on targeted short daily mental practices. These findings could promote the development of evidence-based mental training interventions in clinical, educational, and corporate settings aimed at cultivating social intelligence, prosocial motivation, and cooperation. PMID:28983507

The effects of ingested plastic on growth and survival of albatross chicks

USGS Publications Warehouse

Sievert, Paul R.; Sileo, Louis

1993-01-01

We studied the effects of ingested plastic on the growth and survival of chicks of Laysan Albatrosses Diomedea immutabilis and Black-footed albatrosses D. nigripes on Midway Atoll during the nesting seasons of 1986 and 1987. Weights and proventricular contents of the chicks were determined periodically through the nesting cycle. Large (>22 cm1)volumes of plastic were present in the proventriculi of 27% of the Laysan and 16% of the Black-footed albatross chicks examined by endoscopy. Prior to fledging, albatross chicks regurgitated pellets composed of plastic and other indigestible material from their proventriculi. Laysan Albatross chicks with large volumes of proventricular plastic had asymptotic fledging weights significantly lower (122 g) than did chicks with low amounts of plastic. The effect of depresses fledging weights on postfledging survival was not determined. Plastic had no detectable effect on the growth of Black-footed Albatross chicks. All chicks that died were examined by necropsy. Mechanical lesions from ingested plastic were the cause of death of one of 45 Laysan Albatross chicks examined in 1986, but were not the cause of death of 93 individuals examined in 1987. Dehydration was the most common cause of death. In general, ingested plastic was not a significant direct cause of death in nestlings, but there was some evidence that it may have affected survival in 1986, when the volume of plastic ingested was highest.

The Role of Neuromodulators in Cortical Plasticity. A Computational Perspective

PubMed Central

Pedrosa, Victor; Clopath, Claudia

2017-01-01

Neuromodulators play a ubiquitous role across the brain in regulating plasticity. With recent advances in experimental techniques, it is possible to study the effects of diverse neuromodulatory states in specific brain regions. Neuromodulators are thought to impact plasticity predominantly through two mechanisms: the gating of plasticity and the upregulation of neuronal activity. However, the consequences of these mechanisms are poorly understood and there is a need for both experimental and theoretical exploration. Here we illustrate how neuromodulatory state affects cortical plasticity through these two mechanisms. First, we explore the ability of neuromodulators to gate plasticity by reshaping the learning window for spike-timing-dependent plasticity. Using a simple computational model, we implement four different learning rules and demonstrate their effects on receptive field plasticity. We then compare the neuromodulatory effects of upregulating learning rate versus the effects of upregulating neuronal activity. We find that these seemingly similar mechanisms do not yield the same outcome: upregulating neuronal activity can lead to either a broadening or a sharpening of receptive field tuning, whereas upregulating learning rate only intensifies the sharpening of receptive field tuning. This simple model demonstrates the need for further exploration of the rich landscape of neuromodulator-mediated plasticity. Future experiments, coupled with biologically detailed computational models, will elucidate the diversity of mechanisms by which neuromodulatory state regulates cortical plasticity. PMID:28119596

Medical Student Perception of Plastic Surgery and the Impact of Mainstream Media

PubMed Central

Fraser, S. J.; Al Youha, S.; Rasmussen, P. J.

2017-01-01

Background: Plastic surgery as a discipline is poorly understood by many, including primary care physicians, nurses, medical students, and the public. These misconceptions affect the specialty in a number of ways, including referral patterns and recruitment of medical students into residency programs. The reason for these commonly held misconceptions has not yet been addressed in the plastic surgery literature. As such, we assessed medical students’ knowledge and perceptions of plastic surgery as a discipline and explored factors influencing these opinions. Methods: To assess medical students’ knowledge and perceptions of plastic surgery, we conducted an online survey. A total of 231 medical students responded. Interviews were then conducted with 2 focus groups, in which we explored the survey results and reasons behind these misconceptions. Results: As with previous studies, medical students showed a gap in knowledge with respect to plastic surgery. Although they were generally aware that plastic surgeons perform cosmetic procedures and treat burns, they were largely unaware that plastic surgeons perform hand and craniofacial surgeries. Focus groups revealed that television plays a large role in shaping their ideas of plastic surgery. Conclusion: Medical students have a skewed perception of the discipline of plastic surgery, and this is largely influenced by television. Interventions aimed at educating medical students on the matter are recommended, including a greater presence in the preclerkship medical school curriculum. PMID:29026812

Acoustic far-field of shroud-lip-scattered instability modes of supersonic co-flowing jets

NASA Astrophysics Data System (ADS)

Samanta, Arnab; Freund, Jonathan B.

2013-11-01

We consider the acoustic radiation of instability modes in dual-stream jets, with the inner nozzle buried within the outer shroud, particularly the upstream scattering into acoustic modes that occurs at the shroud lip. For supersonic core jets, several families of instability waves are possible, beyond the regular Kelvin-Helmholtz (K-H) mode, with very different modal shapes and propagation characteristics, which are candidates for changing the sound character of very high-speed jets. The co-axial shear layers are modeled as vortex sheets, with the Wiener-Hopf method used to compute these modes coupled with an asymptotic solution for the far-field radiation. A broadband mode spectra as well as single propagating modes are considered as incident and scattered waves. The resulting far-field directivity patterns are quantified, to show the efficiency of some of these radiation mechanisms, particularly in the upstream direction, which is not directly affected by the Mach-wave-like sound that is radiated from these modes irrespective of any scattering surface. A full Kutta condition, which provides the usual boundary condition at the shroud lip, is altered to examine how vortex shedding, perhaps controllable at the lip, affects the radiated sound.

Mature vs. Active Deep-Seated Landslides: A Comparison Through Two Case Histories in the Alps

NASA Astrophysics Data System (ADS)

Delle Piane, Luca; Perello, Paolo; Baietto, Alessandro; Giorza, Alessandra; Musso, Alessia; Gabriele, Piercarlo; Baster, Ira

2016-06-01

Two case histories are presented, concerning the still poorly known alpine deep-seated gravitational slope deformations (DSD) located nearby Lanzada (central Italian Alps), and Sarre (north-western Italian Alps). The Lanzada DSD is a constantly monitored, juvenile, and active phenomenon, partly affecting an existing hydropower plant. Its well-developed landforms allow a precise field characterization of the instability-affected area. The Sarre DSD is a mature, strongly remodeled phenomenon, where the only hazard factor is represented by secondary instability processes at the base of the slope. In this case, the remodeling imposed the adoption of complementary analytical techniques to support the field work. The two presented studies had to be adapted to external factors, namely (a) available information, (b) geological and geomorphological setting, and (c) final scope of the work. The Lanzada case essentially relied upon accurate field work; the Sarre case was mostly based on digital image and DTM processing. In both cases a sound field structural analysis formed the necessary background to understand the mechanisms leading to instability. A back-analysis of the differences between the study methods adopted in the two cases is finally presented, leading to suggestions for further investigations and design.

Jeans self gravitational instability of strongly coupled quantum plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Prerana, E-mail: preranaiitd@rediffmail.com; Chhajlani, R. K.

2014-07-15

The Jeans self-gravitational instability is studied for quantum plasma composed of weakly coupled degenerate electron fluid and non-degenerate strongly coupled ion fluid. The formulation for such system is done on the basis of two fluid theory. The dynamics of weakly coupled degenerate electron fluid is governed by inertialess momentum equation. The quantum forces associated with the quantum diffraction effects and the quantum statistical effects act on the degenerate electron fluid. The strong correlation effects of ion are embedded in generalized viscoelastic momentum equation including the viscoelasticity and shear viscosities of ion fluid. The general dispersion relation is obtained using themore » normal mode analysis technique for the two regimes of propagation, i.e., hydrodynamic and kinetic regimes. The Jeans condition of self-gravitational instability is also obtained for both regimes, in the hydrodynamic regime it is observed to be affected by the ion plasma oscillations and quantum parameter while in the kinetic regime in addition to ion plasma oscillations and quantum parameter, it is also affected by the ion velocity which is modified by the viscosity generated compressional effects. The Jeans critical wave number and corresponding critical mass are also obtained for strongly coupled quantum plasma for both regimes.« less

Density variations of plastic carriers in metallic glasses during aging

NASA Astrophysics Data System (ADS)

Fan, Yue; Iwashita, Takuya; Egami, Takeshi

Thermally induced deformation in metallic glasses was investigated by sampling the potential energy landscape (PEL) and probing the changes in the atomic properties (e.g. energy, displacement, stress). We demonstrate that there exists a universal plastic carrier in amorphous materials, which corresponds to the hopping between local minima on PEL. However very interestingly, the density of plastic carrier is largely affected by the aging history of the glasses. The higher fictive temperature (i . e . fast cooling rate), the larger density of plastic carrier is contained in the system. In particular, we observe a scaling of ρ~exp(- α/Tfic) , which is consistent with the prediction of shear transformation zone theory. The work is supported by U.S. Department of Energy.